Farmers’ Markets: Positive Feelings of Instagram Posts

Directory of Open Access Journals (Sweden)

Ladislav Pilař

2016-01-01

Full Text Available With increasing consumer requirements, farmers and vendors see the importance of social media as a marketing tool to engage with consumers. In particular, on a more personal level for reasons of brand management. Instagram is becoming increasingly popular as a marketing communication tool. The aim of this paper is to identify areas that users evaluate in terms of positive feelings in connection with farmers’ markets. The results are based on the analysis of the worldwide, and Czech, instagram social network. Instagram posts were identified on the basis of keywords, such as #farmarsketrhy and #farmersmarkets. The results of the study are based on 100,000 contributions on Instagram made by 55,632 users. The analysis contains 1,357,812 ‘unique’ words. The results identified six major areas (1 Healthy (2 Good (3 Great (4 Happy (5 Nice (6 Perfect. An appropriately posted hashtag indicated the positive feelings that were evoked and then assigned to a matching category. The research results are used to identify group characteristics that exert these positive feelings while visiting farmers’ markets. These results can be used to build communications campaigns for farmers’ markets. They can also be used as a basis for further research in defining the behaviour of farmers’ markets visitors, based on cultural differences arising from geographic location.

Design for Global Markets

DEFF Research Database (Denmark)

Boztepe, Suzan

2009-01-01

In a global economy, no company can safely assume that their products will be accepted in foreign markets. One key issue is to understand and meet the latent needs of culturally diverse target markets. This book examines from a user perspective the issue of developing new products for global...... markets. Given that main goal of any design is to create value for users, Boztepe argues that the concept of user value could be a driving force in design decision-making regarding product development for global markets. Through interviews with women about their kitchen practices and observations...... framework to assists marketers, product designers and managers to deal with the complex issue of designing and tailoring products for local needs....

Optimal Market Design

NARCIS (Netherlands)

Boone, J.; Goeree, J.K.

2010-01-01

This paper introduces three methodological advances to study the optimal design of static and dynamic markets. First, we apply a mechanism design approach to characterize all incentive-compatible market equilibria. Second, we conduct a normative analysis, i.e. we evaluate alternative competition and

Marketing in Game Design

OpenAIRE

Nurminen, Emilia

2013-01-01

In my thesis, Marketing in Game Design, I wanted to inspect how developing a game from a purely commercial perspective affects on the game design. The purpose of this thesis is to define the valid aspects of product marketing for games, how they are perceived in game industry and how those aspects affect to the game design. The question I am asking is how to make marketing a fluent part of indie game development process. Through my thesis project, Puzzleplatform, I study how the marketing asp...

[Post-marketing clinical study of traditional Chinese medicine--lessons learned from comprehensive evaluation of Fufang Zaoren capsule].

Science.gov (United States)

Qing, Shan; Gao, Lin; Zhang, Li; Jia, Jian-Ping; Liu, Xin-Min; Ji, Shao-Liang; Yang, Xiao-Hui

2013-11-01

By comprehensive review and analysis of post-marketing clinical research on the efficacy and safety,we concluded that Fufang Zaoren capsule has certain therapeutic effects for insomnia, although current clinical research design needs improving. The post-marketing clinical studies also showed that it causes several adverse reactions at the recommended doses, such as chills, fever, dizziness, nausea, shortness of breath, chest tightness and palpitations, whereas high doses of Fufang Zaoren capsule can cause delayed extrapyramidal symptoms. Health Canada government website also prompted the L-tetrahydropalmatine in Fufang Zaoren capsule caused liver damage in pregnant women. The authors summarized the risk points, factors and risk control in the clinical use of Fufang Zaoren capsule and also present their perspective on the research status, existing problems and corresponding countermeasures in the post-marketing clinical re-evaluation of traditional Chinese medicine.

Preferred supplier contracts in post-patent prescription drug markets.

Science.gov (United States)

Blankart, Carl Rudolf; Stargardt, Tom

2016-02-22

In recent years, the expiration of patents for large drug classes has increased the importance of post-patent drug markets. However, previous research has focused solely on patent drug markets. In this study, the authors evaluate the influence of preferred supplier contracts, the German approach to tendering, in post-patent drug markets using a hierarchical market share attraction model. The authors find that preferred supplier contracts are a powerful strategic instrument for generic manufacturers in a highly competitive environment. They quantify the effects of signing a preferred supplier contract and show that brand-name manufacturers are vulnerable to tendering. Therefore, brand-name manufacturers should readjust their strategies and consider including preferred supplier contracts in their marketing mix. In addition, the authors employ a simulation to demonstrate that a first-mover advantage might be gained from signing a preferred supplier contract. Furthermore, their results can be used as a blueprint for decision makers in the pharmaceutical industry to assess the market share effects of different contracting strategies regarding preferred supplier contracts.

[Thought on several problems of clinical revaluation of post-marketing herb research].

Science.gov (United States)

He, Wei; Xie, Yanming; Wang, Yongyan

2010-06-01

The revaluation of post-marketing herb is a complex research work, which concerns widely content and difficult to put it into practice. The starting of our country's revaluation post-marketing herb was comparatively late. It should profect it both in laws and regulations mechanism as well as technological specification. This article is try to focus on some attention problems in revaluation of postmarketing herb process. Such as the laws and regulations demand, the basement and the subject of revaluation of post-marketing herb.

Market Design and Supply Security in Imperfect Power Markets

DEFF Research Database (Denmark)

Schwenen, Sebastian

2014-01-01

Supply security in imperfect power markets is modelled under different market designs. In a uniform price auction for electricity with two firms, strategic behaviour may leave firms offering too few capacities and unable to supply all realized demand. Market design that relies oncapacity markets...... increases available generation capacities for sufficiently high capacity prices and consequently decreases energy prices. However, equilibrium capacity prices are non-competitive. Capacity markets can increase security of supply, but cannot mitigate market power, which is exercised in the capacity market...

7 CFR 29.37 - Designated market.

Science.gov (United States)

2010-01-01

... 7 Agriculture 2 2010-01-01 2010-01-01 false Designated market. 29.37 Section 29.37 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... INSPECTION Regulations Definitions § 29.37 Designated market. An auction market designated by the Secretary...

Directory of Post-Secondary Retailing and Marketing Vocational Programs.

Science.gov (United States)

American Vocational Association, Inc., Washington, DC.

This directory lists 357 general and 135 special retailing and marketing vocational programs at the post secondary level. Institutions vary somewhat in the identification of general programs; for example, they may be called retailing, merchandising, marketing, mid-management, or distributive education programs. Specialized programs offered by…

Social Media Listening for Routine Post-Marketing Safety Surveillance.

Science.gov (United States)

Powell, Gregory E; Seifert, Harry A; Reblin, Tjark; Burstein, Phil J; Blowers, James; Menius, J Alan; Painter, Jeffery L; Thomas, Michele; Pierce, Carrie E; Rodriguez, Harold W; Brownstein, John S; Freifeld, Clark C; Bell, Heidi G; Dasgupta, Nabarun

2016-05-01

Post-marketing safety surveillance primarily relies on data from spontaneous adverse event reports, medical literature, and observational databases. Limitations of these data sources include potential under-reporting, lack of geographic diversity, and time lag between event occurrence and discovery. There is growing interest in exploring the use of social media ('social listening') to supplement established approaches for pharmacovigilance. Although social listening is commonly used for commercial purposes, there are only anecdotal reports of its use in pharmacovigilance. Health information posted online by patients is often publicly available, representing an untapped source of post-marketing safety data that could supplement data from existing sources. The objective of this paper is to describe one methodology that could help unlock the potential of social media for safety surveillance. A third-party vendor acquired 24 months of publicly available Facebook and Twitter data, then processed the data by standardizing drug names and vernacular symptoms, removing duplicates and noise, masking personally identifiable information, and adding supplemental data to facilitate the review process. The resulting dataset was analyzed for safety and benefit information. In Twitter, a total of 6,441,679 Medical Dictionary for Regulatory Activities (MedDRA(®)) Preferred Terms (PTs) representing 702 individual PTs were discussed in the same post as a drug compared with 15,650,108 total PTs representing 946 individual PTs in Facebook. Further analysis revealed that 26 % of posts also contained benefit information. Social media listening is an important tool to augment post-marketing safety surveillance. Much work remains to determine best practices for using this rapidly evolving data source.

Fatal adverse drug reactions of anticancer drugs detected by all-case post-marketing surveillance in Japan.

Science.gov (United States)

Mori, Jinichi; Tanimoto, Tetsuya; Miura, Yuji; Kami, Masahiro

2015-06-01

All-case post-marketing surveillance of newly approved anticancer drugs is usually conducted on all patients in Japan. The present study investigates whether all-case post-marketing surveillance identifies fatal adverse drug reactions undetected before market entry. We examined fatal adverse drug reactions identified via all-case post-marketing surveillance by reviewing the disclosed post-marketing surveillance results, and determined the time points in which the fatal adverse drug reactions were initially reported by reviewing drug labels. We additionally scanned emergency alerts on the Japanese regulatory authority website to assess the relationship between all-case post-marketing surveillance and regulatory action. Twenty-five all-case post-marketing surveillances were performed between January 1999 and December 2009. Eight all-case post-marketing surveillances with final results included information on all fatal cases. Of these, the median number of patients was 1287 (range: 106-4998), the median number of fatal adverse drug reactions was 14.5 (range: 4-23). Of the 111 fatal adverse drug reactions detected in the eight post-marketing surveillances, only 28 (25.0%) and 22 (19.6%) were described on the initial global and the initial Japanese drug label, respectively, and 58 (52.3%) fatal adverse drug reactions were first described in the all-case post-marketing surveillance reports. Despite this, the regulatory authority issued only four warning letters, and two of these were prompted by case reports from the all-case post-marketing surveillance. All-case post-marketing surveillance of newly approved anticancer drugs in Japan was useful for the rigorous compilation of non-specific adverse drug reactions, but it rarely detected clinically significant fatal adverse drug reactions. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

[Exploration of how to formulate guidelines on post-marketing traditional Chinese medicine surveillance].

Science.gov (United States)

Zhang, Wen; Xie, Yan-Ming; Yu, Wen-Ya

2013-09-01

Combining the world health organization's (WHO), the United States and the European union's relevant laws and guidelines on post-marketing drug surveillance to judge the status of post-marketing surveillance of traditional Chinese medicine(TCM) in China. We found that due to the late start of post-marketing surveillance of traditional Chinese medicine, the appropriate guidelines are yet to be developed. Hence, hospitals, enterprises and research institutions do not have a shared foundation from which to compare their research results. Therefore there is an urgent need to formulate such post-marketing surveillance guidelines. This paper has used as guidance various technical documents such as, "procedures to formulate national standards" and "testing methods of management in formulating traditional Chinese medicine standards" and has combined these to produce a version of post-marketing surveillance particular to Chinese medicine in China. How to formulate these guidelines is discussed and procedures and methods to formulate technical specifications are introduced. These provide a reference for future technical specifications and will assist in the development of TCM.

A theory of planning horizons (1: market design in a post-neoclassical world

Directory of Open Access Journals (Sweden)

Frederic B. Jennings, Jr.

2012-05-01

Full Text Available The neoclassical case supporting competitive frames and market solutions has failed to promote stable world-wide economic development. Other approaches in economics incorporate social culture, increasing returns, market power, ecological limits and complementarity, yielding broader applications for development theory. In this paper a theory of planning horizons is introduced to raise some meaningful questions about the traditional view with respect to its substitution, decreasing returns and independence assumptions. Suppositions of complementarity, increasing returns and interdependence suggest that competition is inefficient by upholding a myopic culture resistant to learning. Growth – though long believed to rise from markets and competitive values – may not derive from these sources. Instead, as civilizations advance, shifting from material wants to higher-order intangible output, they evolve from market tradeoffs (substitution and scarcity into realms of common need (complementarity and abundance. The policy implications of horizonal theory are explored, with respect to regulatory aims and economic concerns. Such an approach emphasizes strict constraints against entry barriers, ecological harm, market power abuse and ethical lapses. Social cohesion – not competition – is sought as a means to extend horizons and thereby increase efficiency, equity and ecological health. The overriding importance of horizon effects for regulatory assessment dominates other orthodox standards in economics and law. Reframing economics along horizonal lines suggests some meaningful insight on the proper design of economic systems.

Designing carbon markets, Part II: Carbon markets in space

International Nuclear Information System (INIS)

Fankhauser, Samuel; Hepburn, Cameron

2010-01-01

This paper analyses the design of carbon markets in space (i.e., geographically). It is part of a twin set of papers that, starting from first principles, ask what an optimal global carbon market would look like by around 2030. Our focus is on firm-level cap-and-trade systems, although much of what we say would also apply to government-level trading and carbon offset schemes. We examine the 'first principles' of spatial design to maximise flexibility and to minimise costs, including key design issues in linking national and regional carbon markets together to create a global carbon market.

The art of designing markets.

Science.gov (United States)

Roth, Alvin E

2007-10-01

Traditionally, markets have been viewed as simply the confluence of supply and demand. But to function properly, they must be able to attract a sufficient number of buyers and sellers, induce participants to make their preferences clear, and overcome congestion by providing both enough time to make choices and a speedy means of registering them. Solutions to these challenges are the province of market design--a blend of game theory and experimental economics. Roth, a professor of both business and economics at Harvard, is a leading market designer. He and his colleagues have rescued failing markets by, for example, designing labor clearinghouses through which U.S. doctors get their first jobs and auctions through which the Federal Communications Commission sells licenses for parts of the radio broadcast spectrum. They have also created marketlike allocation procedures that involve neither prices nor an exchange of money; these include systems for assigning children to schools in Boston and New York and for facilitating exchanges of kidneys. Computers enable the design of "smart markets" that combine the inputs of users in complex ways: In kidney exchange, they run through every possible match of donors and recipients to arrange the greatest possible number of transplants. In the future, computers may make it possible to auction bundled goods, such as airport takeoff and landing slots. As online markets--like those for jobs and dating--proliferate, a growing understanding of markets in general will provide virtually limitless opportunities for market design.

Market design and supply security in imperfect power markets

International Nuclear Information System (INIS)

Schwenen, Sebastian

2014-01-01

Supply security in imperfect power markets is modelled under different market designs. In a uniform price auction for electricity with two firms, strategic behaviour may leave firms offering too few capacities and unable to supply all realized demand. Market design that relies on capacity markets increases available generation capacities for sufficiently high capacity prices and consequently decreases energy prices. However, equilibrium capacity prices are non-competitive. Capacity markets can increase security of supply, but cannot mitigate market power, which is exercised in the capacity market instead of the energy market. - Highlights: • I model two power generating firms who compete to serve stochastic demand in a multiunit uniform price auction. • In equilibrium, blackout probabilities can arise through capacity withholding. • Capacity mechanisms decrease capacity withholding and the expected energy price. • With dominant firms, capacity mechanisms are only effective if capacity prices are non-competitive and include a mark-up for leaving the energy-only market optimum

Progressing towards post-2012 carbon markets

Energy Technology Data Exchange (ETDEWEB)

Soeren Luetken, S.; Holm Olsen, K.

2011-11-15

Confronting the end of the first Kyoto Commitment period in 2012 with no agreed outcome for global cooperation on future emission reductions, there is an urgent need to look for new opportunities for public and private cooperation to drive broad-based progress in living standards and keep projected future warming below the politically agreed 2 degrees Celsius. Responding jointly to these global challenges the United Nations environmental Program (UNEP) and its UNEP Risoe Centre (URC) have in cooperation with the Global Green Growth Institute (GGGI) prepared the Perspectives 2011. The publication focuses on the role of carbon markets in contributing to low carbon development and new mechanisms for green growth, as one core area of action to address the challenges noted above. The publication explores in ten articles, how carbon markets at national, regional and global levels can be developed and up-scaled to sustain the involvement of the private sector in leveraging finance and innovative solutions to reduce greenhouse gas emissions. The titles of the ten articles are: 1) Fragmentation of international climate policy - doom or boom for carbon markets?; 2) Perspectives on the EU carbon market; 3) China carbon market; 4) The national context of U.S. state policies for a global commons problem; 5) Mind the gap - the state-of-play of Canadian greenhouse gas mitigation; 6) Role of the UN and multilateral policies in integrating an increasingly fragmented global carbon market; 7) Making CDM work for poor and rich Africa beyond 2012 - a series of dos and don'ts; 8) Voluntary market - future perspectives; 9) Sectoral approaches as a way forward for the carbon market?; 10) The Durban outcome - a post 2012 framework approach for green house gas markets. (LN)

Progressing towards post-2012 carbon markets

Energy Technology Data Exchange (ETDEWEB)

Soeren Luetken, S; Holm Olsen, K

2011-11-15

Confronting the end of the first Kyoto Commitment period in 2012 with no agreed outcome for global cooperation on future emission reductions, there is an urgent need to look for new opportunities for public and private cooperation to drive broad-based progress in living standards and keep projected future warming below the politically agreed 2 degrees Celsius. Responding jointly to these global challenges the United Nations environmental Program (UNEP) and its UNEP Risoe Centre (URC) have in cooperation with the Global Green Growth Institute (GGGI) prepared the Perspectives 2011. The publication focuses on the role of carbon markets in contributing to low carbon development and new mechanisms for green growth, as one core area of action to address the challenges noted above. The publication explores in ten articles, how carbon markets at national, regional and global levels can be developed and up-scaled to sustain the involvement of the private sector in leveraging finance and innovative solutions to reduce greenhouse gas emissions. The titles of the ten articles are: 1) Fragmentation of international climate policy - doom or boom for carbon markets?; 2) Perspectives on the EU carbon market; 3) China carbon market; 4) The national context of U.S. state policies for a global commons problem; 5) Mind the gap - the state-of-play of Canadian greenhouse gas mitigation; 6) Role of the UN and multilateral policies in integrating an increasingly fragmented global carbon market; 7) Making CDM work for poor and rich Africa beyond 2012 - a series of dos and don'ts; 8) Voluntary market - future perspectives; 9) Sectoral approaches as a way forward for the carbon market?; 10) The Durban outcome - a post 2012 framework approach for green house gas markets. (LN)

Drug- and herb-induced liver injury: Progress, current challenges and emerging signals of post-marketing risk.

Science.gov (United States)

Raschi, Emanuel; De Ponti, Fabrizio

2015-07-08

Drug-induced liver injury (DILI) and herb-induced liver injury is a hot topic for clinicians, academia, drug companies and regulators, as shown by the steadily increasing number of publications in the past 15 years. This review will first provide clues for clinicians to suspect idiosyncratic (unpredictable) DILI and succeed in diagnosis. Causality assessment remains challenging and requires careful medical history as well as awareness of multifaceted aspects, especially for herbs. Drug discontinuation and therapy reconciliation remain the mainstay in patent's management to minimize occurrence of acute liver failure. The second section will address novel agents associated with liver injury in 2014 (referred to as "signals"), especially in terms of clinical, research and drug development implications. Insights will be provided into recent trends by highlighting the contribution of different post-marketing data, especially registries and spontaneous reporting systems. This literature scrutiny suggests: (1) the importance of post-marketing databases as tools of clinical evidence to detect signals of DILI risk; and (2) the need for joining efforts in improving predictivity of pre-clinical assays, continuing post-marketing surveillance and design ad hoc post-authorization safety studies. In this context, ongoing European/United States research consortia and novel pharmaco-epidemiological tools (e.g., specialist prescription event monitoring) will support innovation in this field. Direct oral anticoagulants and herbal/dietary supplements appear as key research priorities.

New Brunswick Market Design Committee : market design issues paper : choice of market model

International Nuclear Information System (INIS)

2001-01-01

A model for the competitive electricity market in New Brunswick was not specified by the White Paper: New Brunswick Energy Policy, published in March 2001. One of the tasks of the Market Design Committee (MDC) is to select a market model for the province. This report was prepared with this objective in mind. It begins by providing a description of the basic functions that must be performed by any electricity system. Different market models will function differently, and a descriptions of how the functions would be performed under each model is presented. Considering the specific size and geographic location of New Brunswick, a number of actual markets that could be of interest are presented. The various electricity markets normally use one of four market models: vertically integrated monopoly utility, a competitive pool market, a bilateral contract market, and a single-buyer market. The first model was not explained as it represents the existing, non-competitive model whereby the government owns and/or regulates price and investment decision. The case where a market operator receives bids and offers from buyers and sellers and matches them to derive a price and schedule for the spot market is what is called the competitive pool market. When electricity trade takes place through a series of contracts between individual buyers and sellers, it is referred to as a bilateral contract market. Finally, the single-buyer market is defined as a monopoly where the buyer purchases from multiple sellers based on competition amongst them. Different examples are provided of applications of the three markets described in the paper. Both New England and New Zealand were chosen to better illustrate the concepts of a fully competitive pool-based market, as they either have close ties to New Brunswick, or share physical similarities. The single-buyer model is illustrated by the case of Northern Ireland where size is similar. The choices made in Quebec were described in the final

[Application of Markov model in post-marketing pharmacoeconomic evaluation of traditional Chinese medicine].

Science.gov (United States)

Wang, Xin; Su, Xia; Sun, Wentao; Xie, Yanming; Wang, Yongyan

2011-10-01

In post-marketing study of traditional Chinese medicine (TCM), pharmacoeconomic evaluation has an important applied significance. However, the economic literatures of TCM have been unable to fully and accurately reflect the unique overall outcomes of treatment with TCM. For the special nature of TCM itself, we recommend that Markov model could be introduced into post-marketing pharmacoeconomic evaluation of TCM, and also explore the feasibility of model application. Markov model can extrapolate the study time horizon, suit with effectiveness indicators of TCM, and provide measurable comprehensive outcome. In addition, Markov model can promote the development of TCM quality of life scale and the methodology of post-marketing pharmacoeconomic evaluation.

Design choices for electricity markets

Energy Technology Data Exchange (ETDEWEB)

De Vries, Laurens

2007-07-01

Ten years after the first European Electricity Directive, the goal of creating a single European electricity market has not been reached, despite concerted efforts by the EU and certain member states to continue with the reforms. The policy of subsidiarity for many aspects of market design has as a consequence that member countries are implementing a variety of different market designs and are implementing the reforms at varying speeds. The Florence regulatory process, which was intended to provide a bottom-up approach for coordination and harmonization, has effectively stalled and been replaced by a series of 'mini fora' in which smaller groups of countries work on integrating their markets. At the same time, the European electricity supply industry is facing some significant challenges. This paper investigates the different choices that can be made in the design of electricity markets, how they relate to each other and how they relate to the policy goals. (auth)

Contribution of industry funded post-marketing studies to drug safety: survey of notifications submitted to regulatory agencies

Science.gov (United States)

Prugger, Christof; Doshi, Peter; Ostrowski, Kerstin; Witte, Thomas; Hüsgen, Dieter; Keil, Ulrich

2017-01-01

Objectives To investigate the practice of post-marketing studies in Germany during a three year period and to evaluate whether these trials meet the aims specified in the German Medicinal Products Act. Design Survey of notifications submitted to German regulatory agencies before post-marketing studies were carried out, 2008-10. Setting Notifications obtained through freedom of information requests to the three authorities responsible for registering post-marketing studies in Germany. Main outcome measures Descriptive statistics of post-marketing studies, including the products under study, intended number of patients, intended number of participating physicians, proposed remunerations, study plan and protocol, and availability of associated scientific publications and reports on adverse drug reactions. Results Information was obtained from 558 studies, with a median of 600 (mean 2331, range 2-75 000) patients and 63 (270, 0-7000) participating physicians per study. The median remuneration to physicians per patient was €200 (€441, €0-€7280) (£170, £0-£6200; $215, $0-$7820), with a total remuneration cost of more than €217m for 558 studies registered over the three year period. The median remuneration per participating physician per study was €2000 (mean €19 424), ranging from €0 to €2 080 000. There was a broad range of drugs and non-drug products, of which only a third represented recently approved drugs. In many notifications, data, information, and results were, by contract, strictly confidential and the sole property of the respective sponsor. No single adverse drug reaction report could be identified from any of the 558 post-marketing studies. Less than 1% of studies could be verified as published in scientific journals. Conclusions Post-marketing studies are not improving drug safety surveillance. Sample sizes are generally too small to allow the detection of rare adverse drug reactions, and many participating physicians are

Post-neoliberal electricity market 're-reforms' in Argentina. Diverging from market prescriptions?

International Nuclear Information System (INIS)

Haselip, James; Potter, Clive

2010-01-01

This paper focuses upon the policy and institutional change that has taken place within the Argentine electricity market since the country's economic and social crisis of 2001/2. As one of the first less developed countries (LDCs) to liberalise and privatise its electricity industry, Argentina has since moved away from the orthodox market model after consumer prices were frozen by the Government in early 2002 when the national currency was devalued by 70%. Although its reforms were widely praised during the 1990s, the electricity market has undergone a number of interventions, ostensibly to keep consumer prices low and to avert the much-discussed energy 'crisis' caused by a dearth of new investment combined with rising demand levels. This paper explores how the economic crisis and its consequences have both enabled and legitimised these policy and institutional amendments, while drawing upon the specifics of the post-neoliberal market 're-reforms' to consider the extent to which the Government appears to be moving away from market-based prescriptions. In addition, this paper contributes to sector-specific understandings of how, despite these changes, neoliberal ideas and assumptions continue to dominate Argentine public policy well beyond the postcrisis era. (author)

[The importance of defining methodology for post-marketing observational studies on cardiovascular therapies].

Science.gov (United States)

Pelliccia, Francesco; Barillà, Francesco; Tanzilli, Gaetano; Viceconte, Nicola; Paravati, Vincenzo; Mangieri, Enrico; Gaudio, Carlo

2017-01-01

In recent years, a growing number of observational studies in cardiology have been carried out following the criticism that rigid design of randomized clinical trials produces information that is not applicable to the general patient. This approach is very common in several branches of medicine, first of all oncology, but has often been considered marginal in cardiology. The recent introduction of new oral anticoagulants (NOACs) on the market, however, has seen a proliferation of "real-life" studies, drawing the attention of cardiologists to the advantages and limitations of post-marketing studies. NOACs have been approved for use on the basis of large randomized clinical trials that have clearly documented their efficacy and safety. Since they have become available, the analysis of phase IV data has been considered crucial and therefore a great amount of information on the use of NOACs in daily practice has become available. It should be considered, however, that the possibility exists that results obtained from "real-world" studies, which do not apply rigid scientific criteria, may lead to incorrect conclusions. Accordingly, it is mandatory to fully define the operational standards of observational studies. All the protagonists of post-marketing analysis (physicians, epidemiologists, pharmacologists, statisticians) should handle the data strictly in order to ensure their reliability and comparability with other studies. To this end, it is crucial that researchers follow rigorous operational protocols for phase IV studies. Briefly, any "real-life" study should be prospective and adhere to what is prespecified by the research protocol - which must illustrate the background and rationale of the study, define its primary endpoint, and detail the methods, i.e. study design, population and variables.

The economic analysis of power market architectures: application to real-time market design

International Nuclear Information System (INIS)

Saguan, M.

2007-04-01

This work contributes to the economic analysis of power market architectures. A modular framework is used to separate problems of market design in different modules. The work's goal is to study real-time market design. A two-stage market equilibrium model is used to analyse the two main real-time designs: the 'market' and the 'mechanism' (with penalty). Numerical simulations show that design applied in real-time is not neutral vis-a-vis of energy markets sequence and the competition dynamic. Designs using penalty (mechanisms) cause distortions, inefficiencies and can create barriers to entry. The size of distortions is given by the temporal position of the gate that closure the forward markets. This model has also allowed us to show the key role of real-time integration between zones and the importance of good harmonization between real-time designs of each zone. (author)

Electricity market design for the future

OpenAIRE

robinson, david; Keay, Malcolm

2017-01-01

This paper explains why current electricity markets are not fit for purpose and propose a new market design. Electricity markets operating today were designed for the technical and economic conditions of the 1990's. These conditions have changed substantially, especially with increased penetration of intermittent renewables and the growing potential for distributed energy resources and consumer involvement. Today's markets are incompatible with these trends. They do not provide h...

Post-Project Market Review as a Tool for Stimulating Commercialisation of Knowledge Creation Projects

NARCIS (Netherlands)

Bout, Y.; Lombaers, Jaap H.M.; Constantinides, Efthymios; Fisscher, O.A.M.; de Weerd-Nederhof, Petronella C.; Oakey, R.; Groen, A.; Cook, G.; van der Sijde, P.

2009-01-01

Post-Project Reviews are mainly used as a tool to improve organisational learning (Busby, 1999; von Zedtwitz, 2002). However, post-project reviews can also be used as a tool to identify new market potential and to hand over technical knowledge from technical to marketing personnel (von Zedtwitz,

Post market surveillance in the german medical device sector - current state and future perspectives.

Science.gov (United States)

Zippel, Claus; Bohnet-Joschko, Sabine

2017-08-01

Medical devices play a central role in the diagnosis and treatment of diseases but also bring the potential for adverse events, hazards or malfunction with serious consequences for patients and users. Medical device manufacturers are therefore required by law to monitor the performance of medical devices that have been approved by the competent authorities (post market surveillance). Conducting a nationwide online-survey in the German medical device sector in Q2/2014 in order to explore the current status of the use of post market instruments we obtained a total of 118 complete data sets, for a return rate of 36%. The survey included manufacturers of different sizes, producing medical devices of all risk classes. The post market instruments most frequently reported covered the fields of production monitoring and quality management as well as literature observation, regulatory vigilance systems, customer knowledge management and market observation while Post Market Clinical Follow-up and health services research were being used less for product monitoring. We found significant differences between the different risk classes of medical devices produced and the intensity of use of post market instruments. Differences between company size and the intensity of instruments used were hardly detected. Results may well contribute to the development of device monitoring which is a crucial element of the policy and regulatory system to identify device-related safety issues. Copyright © 2017 Elsevier B.V. All rights reserved.

Essays on Market Design

DEFF Research Database (Denmark)

Liu, Yun

market mechanisms; in addition, how to design alternative mechanisms that can more effectively allocate scarce resources with diverse economic and social goals. Chapter 1 studies the impact of affirmative action policies in the context of school choice. It addresses the following two questions: what...... that bidders’ strategic behavior essentially comes from their diverse market positions (i.e., the winning probability and the probability of deciding the market-clearing price). That is, if a bidder has a relatively strong market position, she has less incentive to shade her bid for the second unit in a UPA...

Post-project market review as a tool for stimulating commercialisation of knowledge creation projects

NARCIS (Netherlands)

Bout, L.Y.; Lombaers, J.H.M.; Constantinides, E.; Weerd-Nederhof, P.C. de

2009-01-01

Post-Project Reviews are mainly used as a tool to improve organisational learning (Busby, 1999; von Zedtwitz, 2002). However, the concept of post-project review can also be used as a tool to identify new market potential and to hand over technical knowledge from technical to marketing personnel (von

Design of energy markets and environment

International Nuclear Information System (INIS)

Birk Mortensen, J.; Olsen, O.J.; Skytte, K.

1999-01-01

The introduction of competition in electricity and gas markets has necessitated the creation of new markets, power pools and financial markets. Such markets are well known from other industries (e.g. oil) but have not been applied for the gas and electricity industries during the monopoly era. To which extent can market design applied elsewhere be transferred to gas and electricity and to which extent must they be modified? The interest in new market designs has recently been extended to environmentally goals, but existing policies to encourage them are considered inefficient and a burden for the state budget. This conference brings some of these subjects into focus. (au)

[Clinical orientation and thought on several problems in post-marketed reassessment of traditional Chinese medicine].

Science.gov (United States)

Wang, Xin; Su, Xia; Yu, Jie; Xie, Yanming; Wang, Yongyan

2011-10-01

The post-marketed reassessment is an important link to ensure the safety and effectiveness of traditional chinese medicine. It is also the expansion and stretch of new drug evaluation. Through the systematic, standard, rigorous post-marketed reassessment, the enterprise can full access to drugs after listing the efficacy and safety information, evaluate the interests and risk of the drug and provide the scientific basis for the drug use. It can also provide timely, scientific technology basis for government health decisions, the enterprise marketing decision and public health security. This paper mainly discussed the thought on clinical orientation of traditional chinese medicine in the post-marketed reassessment and how to reach the goal through systematic consideration and overall plan.

Considering the post-1995 enrichment market

International Nuclear Information System (INIS)

Gunter, L.

1994-01-01

World demand for uranium enrichment services is likely to grow only a little over the next decade, from the current 28 million separative work units (SWU) per year to 33 MSWU per year. Much of the growth will come from Asia where nuclear generating capacity is still increasing. The current situation of the primary enrichment companies is summarized. The primary Western suppliers, Cogema, United States Enrichment Corporation and Urenco, are competing for increased market share in the USA, Europe and Asia as utilities purchase their post-1995 requirements. Entry of the Russian enrichment company, Tenex, into Western markets has been limited by trade restrictions. As a consequence of disarmament, blended weapons material has resulted in a surplus of low-enriched uranium. Together with over-capacity amongst the primary enrichers this has led to an expectation that reduced prices will be negotiable in the medium term. (3 figures). (UK)

[Designs and thoughts of real world integrated data warehouse from HIS on re-evaluation of post-maketing traditional Chinese medicine].

Science.gov (United States)

Zhuang, Yan; Xie, Bangtie; Weng, Shengxin; Xie, Yanming

2011-10-01

To discuss the feasibility and necessity of using HIS data integration to build large data warehouse system which is extensively used on re-evaluation of post-marketing traditional Chinese medicine, and to provide the thought and method of the overall design for it. With domestic and overseas' analysis and comparison on clinical experiments' design based on real world using electronic information system, and with characteristics of HIS in China, a general framework was designed and discussed which refers to design thought, design characteristics, existing problems and solutions and so on. A design scheme of HIS data warehouse on re-evaluation of post-marketing traditional Chinese medicine was presented. The design scheme was proved to be high coherence and low coupling, safe, Universal, efficient and easy to maintain, which can effectively solve the problems many hospitals have faced during the process of HIS data integration.

Evaluation of Market Design Programme - Phase IV; Utvaerdering av Market Designprogrammet - etapp IV

Energy Technology Data Exchange (ETDEWEB)

Wall, Tomas

2013-08-15

The Market Design program was established in year 2000 to study issues related to markets, regulations and policy instruments related to the deregulation of the Swedish electricity market. Through the years, the focus has widened to include not only Sweden but also international cooperation on these issues. The fourth phase of the program is now underway between the years 2010 and 2013. The overall project objective of this fourth phase is to increase knowledge about the Nordic and North European electricity market. Specific objective is to create new knowledge that affects market design of the single market area (Nordic, EU) and to contribute to constructive meetings between researchers, energy companies and government agencies on Market Design Issues. The purpose of the evaluation of the Market Design Program phase IV has been to investigate the results and benefits of the program in relation to the program's original objectives and to examine the need for and areas of further research and possible ways for the research in Market Design. The evaluation has been carried through in four phases during spring and summer 2013. The work has included reading, interviews with program stakeholders, analysis and reporting.

Condom social marketing program to prevent HIV/AIDS in post-conflict Liberia.

Science.gov (United States)

Harris, A O; Jubwe, S; Kennedy, S B; Taylor, C H; Martin, R B; Bee, E M; Perry, O S; Massaquoi, M T; Woods, D V; Barbu, E M

2011-08-01

Youths in sub-Saharan Africa (SSA) account for a large burden of the global HIV/STI crises. As such, strategies directed at promoting behavioral modifications would be critical to reducing the prevalence of risky sexual behaviors among high risk adolescents in post-conflict environments. This study describes a condom promotion strategy to prevent HIV/STIs among highly vulnerable urban youth in a post-conflict, resource-constrained environment via the provision of both male and female condoms to nontraditional venues like music and photo shops, ice cream parlors, money exchange centers and beauty salons. Community members in the designated catchment areas volunteered their services and the use of their small businesses to support this endeavor. In this paper, we describe the condom promotion strategy and its implications within the context of a community-based participatory social marketing program to prevent risky sexual behaviors among highly vulnerable urban youth in a post-conflict country. We postulate that this approach may likely increase condom use among urban youth in Monrovia, the capital city of Liberia.

[Post-marketing drug safety-risk management plan(RMP)].

Science.gov (United States)

Ezaki, Asami; Hori, Akiko

2013-03-01

The Guidance for Risk Management Plan(RMP)was released by the Ministry of Health, Labour and Welfare in April 2012. The RMP consists of safety specifications, pharmacovigilance plans and risk minimization action plans. In this paper, we outline post-marketing drug safety operations in PMDA and the RMP, with examples of some anticancer drugs.

Capacity Market Design: Motivation and Challenges in Alberta’s Electricity Market

Directory of Open Access Journals (Sweden)

David Brown

2018-03-01

Full Text Available Alberta’s electricity market is currently undergoing a period of substantial transition. The province should proceed with caution as it switches from an energy-only electricity market to a capacity market by 2021. Many other jurisdictions have already made the changeover and Alberta can learn from their experiences in order to avoid common mistakes and pitfalls that can arise with the deployment of a capacity market.There were growing concerns that the existing electricity market structure would not attract sufficient investment from conventional generation (e.g., natural gas due to the increased penetration of zero marginal cost renewable generation. As a result, the Alberta government has chosen to transition to a capacity market. For consumers, a capacity market aims to ensure there is sufficient investment in new generation capacity to “keep the lights on” and reduce price swings in the wholesale market. The capacity market will also help the province meet its goals for attracting investors and transitioning away from its dependence on coal-fired electricity generation.However, a switchover is not as simple as it sounds. In an energy-only market, firms are paid solely based on the provision of electricity in hourly wholesale markets. In capacity markets, electricity-generating firms are also paid for providing generation capacity, reflecting the potential to provide electricity at some point in the future. While capacity markets can help ensure there is a reliable supply of electricity, there are several challenges in the implementation of capacity markets. This paper discusses the motivation for the adoption of capacity markets, highlights challenges regulators face when implementing this market design in the context of Alberta, and summarizes the key trade-offs associated with energy-only versus capacity market designs.Relative to an energy-only market, a capacity market is more complex and requires that regulators specify numerous

Subcontracting, Posted Migrants and Labour Market Segmentation in Finland

NARCIS (Netherlands)

Lillie, Nathan

Using evidence from the shipbuilding and construction industries in Finland, this article shows how trade union responses to the introduction of migrant workers can be conditioned by product markets. Growing numbers of posted workers, or intra-European Union work migrants employed via transnational

Enforcing Margin Squeeze Ex Post Across Converging Telecommunications Markets

DEFF Research Database (Denmark)

Bergqvist, Christian; Townsend, John

, delay profitability or limit their ability to remain or expand on markets. However, traditional market definitions are being challenged by (1) the technological convergence of services and (2) innovative product offerings taking advantage of this convergence. Consumers now routinely purchase a bundle...... and innovation present both theoretical and practical difficulties for assessing “muddled margins” on telecoms markets. New and different enforcement approaches to exclusion will have to be formulated within the Article 102 framework and tested in the Courts. This may even require abstaining from applying...... Article 102 TFEU during material periods of convergence, and confining ex post enforcement activity to sector regulation, even when this is inferior for safeguarding effective competition....

Evaluation of Market Design Agents: The Mertacor Perspective

Science.gov (United States)

Stavrogiannis, Lampros C.; Mitkas, Pericles A.

The annual Trading Agent Competition for Market Design, CAT, provides a testbed to study the mechanisms that modern stock exchanges use in their effort to attract potential traders while maximizing their profit. This paper presents an evaluation of the agents that participated in the 2008 competition. The evaluation is based on the analysis of the CAT finals as well as on the results obtained from post-tournament experiments. We present Mertacor, our entrant for 2008, and compare it with the other available agents. In addition, we introduce a simple yet effective way of computing the global competitive equilibrium that Mertacor utilizes and discuss its importance for the game.

INDUSTRIAL DESIGN ELEMENTS IN MARKETING

Directory of Open Access Journals (Sweden)

TOCARIU Liliana

2015-06-01

Full Text Available Industrial design represents an important 20th century phenomenon, which contributed to the spectacular development of human society. There are a lot of domains in which the insertion of the industrial design methods and theories is extremely necessary, becoming common practice. Marketing uses industrial design elements in order to draw up advertisements for products, to develop logos or packaging with all its attached factors, to organise promotional sales with the view of penetrating a certain market or of appealing to a large number of consumers.

Estimating post-marketing exposure to pharmaceutical products using ex-factory distribution data.

Science.gov (United States)

Telfair, Tamara; Mohan, Aparna K; Shahani, Shalini; Klincewicz, Stephen; Atsma, Willem Jan; Thomas, Adrian; Fife, Daniel

2006-10-01

The pharmaceutical industry has an obligation to identify adverse reactions to drug products during all phases of drug development, including the post-marketing period. Estimates of population exposure to pharmaceutical products are important to the post-marketing surveillance of drugs, and provide a context for assessing the various risks and benefits, including drug safety, associated with drug treatment. This paper describes a systematic approach to estimating post-marketing drug exposure using ex-factory shipment data to estimate the quantity of medication available, and dosage information (stratified by indication or other factors as appropriate) to convert the quantity of medication to person time of exposure. Unlike the non-standardized methods often used to estimate exposure, this approach provides estimates whose calculations are explicit, documented, and consistent across products and over time. The methods can readily be carried out by an individual or small group specializing in this function, and lend themselves to automation. The present estimation approach is practical and relatively uncomplicated to implement. We believe it is a useful innovation. Copyright 2006 John Wiley & Sons, Ltd.

Market designs for a completely renewable power sector

Energy Technology Data Exchange (ETDEWEB)

Winkler, Jenny [Fraunhofer-Institut fuer System- und Innovationsforschung (ISI), Karlsruhe (Germany); Altmann, Matthias [Ludwig-Boelkow-Systemtechnik GmbH, Ottobrunn (Germany)

2012-06-15

The article discusses whether the current German electricity market design is suitable for an electricity system completely based on renewable sources, and analyzes alternatives. Such a system becomes ever more likely due to the phase-out of nuclear power and the carbon reduction targets. Various existing scenarios for a completely renewable electricity system are analyzed and compared with respect to the contribution of different renewable technologies. Challenges for the market design arising from the differences between the current and a completely renewable system are identified - notably problems with cost recovery and investment incentives, an increased need for balancing and/or intraday adjustments, an increased diversity of actors, grid congestion and the continuing occurrence of market power. The current market design's ability to solve these issues is assessed with the result that all but the critical problem of investment incentives and cost recovery can be solved by adapting certain rules. A comparison with other suggested market designs reveals that some designs could ensure cost recovery and investment incentives. However, these market designs have other drawbacks. Therefore, the identification of the optimal market design for a completely renewable electricity system requires further research regarding the qualitative and quantitative effects of different changes to the current market design. The article concludes by developing concrete policy recommendations. (orig.)

Electricity Market Manipulation: How Behavioral Modeling Can Help Market Design

Energy Technology Data Exchange (ETDEWEB)

Gallo, Giulia [National Renewable Energy Lab. (NREL), Golden, CO (United States)

2015-12-18

The question of how to best design electricity markets to integrate variable and uncertain renewable energy resources is becoming increasingly important as more renewable energy is added to electric power systems. Current markets were designed based on a set of assumptions that are not always valid in scenarios of high penetrations of renewables. In a future where renewables might have a larger impact on market mechanisms as well as financial outcomes, there is a need for modeling tools and power system modeling software that can provide policy makers and industry actors with more realistic representations of wholesale markets. One option includes using agent-based modeling frameworks. This paper discusses how key elements of current and future wholesale power markets can be modeled using an agent-based approach and how this approach may become a useful paradigm that researchers can employ when studying and planning for power systems of the future.

[Opportunity and challenge of post-marketing evaluation of traditional Chinese medicine].

Science.gov (United States)

Du, Xiao-Xi; Song, Hai-Bo; Ren, Jing-Tian; Yang, Le; Guo, Xiao-Xin; Pang, Yu

2014-09-01

Post-marketing evaluation is a process which evaluate the risks and benefits of drug clinical application comprehensively and systematically, scientific and systematic results of post-marketing evaluation not only can provide data support for clinical application of traditional Chinese medicine, but also can be a reliable basis for the supervision department to develop risk control measures. With the increasing demands for treatment and prevention of disease, traditional Chinese medicine has been widely used, and security issues are also exposed. How to find risk signal of traditional Chinese medicine in the early stages, carry out targeted evaluation work and control risk timely have become challenges in the development of traditional Chinese medicine industry.

New Brunswick Market Design Committee : First interim report

International Nuclear Information System (INIS)

2001-10-01

In June 2001, a Market Design Committee was appointed by the Government of New Brunswick tp provide some advice on the best ways to implement the electricity restructuring initiatives detailed in a White Paper on energy policy in New Brunswick. The Market Design Committee is a very technical committee that was set up with a number of goals in mind: make recommendations concerning all codes and operating protocols, make recommendations on market surveillance and the establishment of a workable competitive market, take into account the reliability of supply for New Brunswick, address ways by which to avoid rate shock to existing self-generators, make recommendations for mitigation of market power in the wholesale and large retail markets, evaluate methods of stranded cost recovery, make recommendations on the requirement for reciprocity in New Brunswick electricity market design, and review the role and treatment of small-scale, on-site electricity generation and make recommendations. The final recommendations are set to be presented in April 2002. This document details the progress realized to date and outlines the plans made for the subsequent phases of the work. The different topics discussed in this document each form the basis for one section of the report. They are: market design committee constitution and process, basic market model, market power issues, transmission issues, environment and renewables, and next steps for the market design committee

On the Design of Artificial Stock Markets

NARCIS (Netherlands)

K. Boer-Sorban (Katalin); A. de Bruin (Arie); U. Kaymak (Uzay)

2005-01-01

textabstractArtificial stock markets are designed with the aim to study and understand market dynamics by representing (part of) real stock markets. Since there is a large variety of real stock markets with several partially observable elements and hidden processes, artificial markets differ

Maintenance of vascular endothelial cell-specific properties after immortalization with an amphotrophic replication-deficient retrovirus containing human papilloma virus 16 E6/E7 DNA

NARCIS (Netherlands)

Fontijn, R.; Hop, C.; Brinkman, H. J.; Slater, R.; Westerveld, A.; van Mourik, J. A.; Pannekoek, H.

1995-01-01

Primary human vascular endothelial cells were immortalized by the integration of a single DNA copy of an amphotrophic, replication-deficient retrovirus containing the E6/E7 genes of human papilloma virus. To date, the resulting cell lines, designated EC-RF7 and EC-RF24, have been cultured for more

The economic analysis of power market architectures: application to real-time market design; L' analyse economique des architectures de marche electrique: application au market design du temps reel

Energy Technology Data Exchange (ETDEWEB)

Saguan, M

2007-04-15

This work contributes to the economic analysis of power market architectures. A modular framework is used to separate problems of market design in different modules. The work's goal is to study real-time market design. A two-stage market equilibrium model is used to analyse the two main real-time designs: the 'market' and the 'mechanism' (with penalty). Numerical simulations show that design applied in real-time is not neutral vis-a-vis of energy markets sequence and the competition dynamic. Designs using penalty (mechanisms) cause distortions, inefficiencies and can create barriers to entry. The size of distortions is given by the temporal position of the gate that closure the forward markets. This model has also allowed us to show the key role of real-time integration between zones and the importance of good harmonization between real-time designs of each zone. (author)

Post-crisis asymmetries of the world market development of banking services

Directory of Open Access Journals (Sweden)

Vladyslav Тіpanov

2011-09-01

Full Text Available In the article there were analyzed theoretical backgrounds for defining the concept «banking service» by scientists from different countries: considered its main characteristics and classification, determined the key peculiarities of the world market functioning of banking services and its structure, found out the present-day developments of the world market of banking services under conditions of post-crisis period.

Market Aspects of an Interior Design Program.

Science.gov (United States)

Gold, Judy E.

A project was conducted to evaluate a proposed interior design program in order to determine the marketability (job availability in the field of interior design and home furnishings merchandising) and the feasibility (educational requirements for entrance into the interior design and home furnishings merchandising job market) of the program. To…

Electricity market design of the future

International Nuclear Information System (INIS)

Peek, Markus; Diels, Robert

2016-01-01

The transformation of the power generation system, to one in which renewable energies will form a cornerstone, will change the requirements for all market actors. To achieve the goals of the German Energiewende ('energy transition'), greater flexibility in production and consumption is of particular importance. Flexibility enables the cost-effective integration of the fluctuating actual feed-in of renewable energies. On the one hand, the technical options for reducing existing technical inflexibilities are given to a considerable extent. On the other hand, analyses of the transnational compensation effects of load and renewable energy supply (RES) feed-in show that flexibility requirements can be reduced significantly in a common electricity market. Electricity markets in which there is open technological competition are an appropriate instrument for the flexibilization of the power supply system. In the short term, the mechanisms of competitive electricity markets ensure an efficient synchronization of supply and demand. Over the medium and long term, the market creates efficient incentives to adapt the generation system and the behavior of consumers to future needs, resulting from the changes in the residual load structure. But at the same time, in recent years the occurrence of negative electricity prices in situations with significantly positive residual loads show that flexibility restraints exist. The causes of these restraints are at least partly due to the market design or the regulatory framework. On the one hand, there are barriers to market entry and, on the other hand, price signals from the electricity markets do not reach all market actors or reach them distortedly. To enable the cost effective development of the different flexibility options in an open technology competition, restraints resulting from market design and the regulatory framework (e. g. in the framework of grid charges, the market and product design of control power markets

Essays on market design and strategic behaviour in energy markets

International Nuclear Information System (INIS)

Lorenczik, Stefan

2017-01-01

The thesis at hand consists of four essays which are divided into two parts. In the first part, consisting of the first two essays, market design issues in electricity markets are discussed. More precisely, it deals with concerns regarding security of supply: First, the concerns regarding the availability of sufficient flexibility to cope with intermittent renewable energy electricity generation. And second, the consequences of insufficient investments signals in energy only markets in interconnected electricity markets. Part two deals with strategic behaviour in spatial natural resource markets. Strategic behaviour and the exertion of market power have always been a matter of concern in energy markets, especially in natural resource markets. The exertion of market power can result in deadweight losses - regulatory bodies try to address this by market regulations aiming for a welfare maximising market outcome. The first problem is to detect collusive behaviour as available data is frequently limited. The second question is how regulatory decisions may influence the market outcome. Both topics are investigated by using the example of the international metallurgical coal market.

Essays on market design and strategic behaviour in energy markets

Energy Technology Data Exchange (ETDEWEB)

Lorenczik, Stefan

2017-11-13

The thesis at hand consists of four essays which are divided into two parts. In the first part, consisting of the first two essays, market design issues in electricity markets are discussed. More precisely, it deals with concerns regarding security of supply: First, the concerns regarding the availability of sufficient flexibility to cope with intermittent renewable energy electricity generation. And second, the consequences of insufficient investments signals in energy only markets in interconnected electricity markets. Part two deals with strategic behaviour in spatial natural resource markets. Strategic behaviour and the exertion of market power have always been a matter of concern in energy markets, especially in natural resource markets. The exertion of market power can result in deadweight losses - regulatory bodies try to address this by market regulations aiming for a welfare maximising market outcome. The first problem is to detect collusive behaviour as available data is frequently limited. The second question is how regulatory decisions may influence the market outcome. Both topics are investigated by using the example of the international metallurgical coal market.

Electricity market design and risk management

International Nuclear Information System (INIS)

Boschi, Federico; Cervigni, Guido

2005-01-01

We show that each wholesale electricity market design trades-off between efficiency and liquidity. Efficiency requires that the product traded in the wholesale market closely reflect the physical features of electricity. Liquidity requires standardization of the products that ore traded on the wholesale market. We stress that Iiquidity comes at a cost since an excessive degree of standardization may lead to significant inefficiencies and forge wealth transfers among market participants [it

Designing carbon markets. Part I: Carbon markets in time

International Nuclear Information System (INIS)

Fankhauser, Samuel; Hepburn, Cameron

2010-01-01

This paper analyses the design of carbon markets in time (i.e., intertemporally). It is part of a twin set of papers that ask, starting from first principles, what an optimal global carbon market would look like by around 2030. Our focus is on firm-level cap-and-trade systems, although much of what we say would also apply to government-level trading and carbon offset schemes. We examine the 'first principles' of temporal design that would help to maximise flexibility and to minimise costs, including banking and borrowing and other mechanisms to provide greater carbon price predictability and credibility over time.

Decoupling the Oil and Gas Prices. Natural Gas Pricing in the Post-Financial Crisis Market

International Nuclear Information System (INIS)

Kanai, Miharu

2011-01-01

This paper looks into natural gas pricing in the post-financial crisis market and, in particular, examines the question whether the oil-linked gas pricing system has outlived its utility as global gas markets mature and converge more rapidly than expected and as large new resources of unconventional gas shift the gas terms-of-trade. Two opposing natural gas pricing systems have coexisted for the last two decades. On the one hand, there is traditional oil-linked pricing, used in pipeline gas imports by Continental European countries and in LNG imports by the countries in Far East. The other is the system led by futures exchanges in deregulated, competitive markets largely in the UK and the US. World gas markets are changing and the basis and mechanisms of price formation are changing with them. There is no reason to expect a revolution in gas pricing, but formulas designed to address the challenges of the 1970's will need to adjust to the realities of the present and expectations for the 21. century. Because such changes will imply a redistribution of costs and benefits, vested shareholders will defend the status quo. But hopefully and ultimately, appropriately regulated markets will assert themselves and shareholders along the entire value chain will have their interests served

A data-capture system for post-marketing surveillance of drugs that integrates with hospital electronic health records

Directory of Open Access Journals (Sweden)

Yamamoto K

2011-04-01

Full Text Available Keiichi Yamamoto1, Shigemi Matsumoto2, Kazuhiro Yanagihara2, Satoshi Teramukai1, Masanori Fukushima1,2,31Department of Clinical Trial Design and Management, Translational Research Center, Kyoto University Hospital, Kyoto, Japan; 2Outpatient Oncology Unit, Kyoto University Hospital, Kyoto, Japan; 3Translational Research Informatics Center, Foundation for Biomedical Research and Innovation, Kobe, JapanPurpose: In conventional clinical studies, the cost of data management for the purposes of quality control tend to be high and collecting paper-based case report forms (CRFs can be burdensome, because paper-based CRFs must be developed and filled out for each clinical study protocol. Use of electronic health records (EHRs for this purpose could reduce costs and improve data quality in clinical studies. Kyoto University Hospital launched an EHR system in January 2005. At the same time, a replicate of that database was established for other purposes. At the Outpatient Oncology Unit of Kyoto University Hospital we developed a data-capture system that includes a cancer clinical database system and a data warehouse for outcomes studies. This system allows us to accumulate data at low cost and apply it to various uses in clinical or outcomes studies. Here we report on the application of this system to the post-marketing surveillance of drugs.Methods: We evaluated the availability of this system and identified problems for future development. With this system investigators can register cases for post-marketing surveillance, and the registered cases are listed on a screen. When CRFs for a particular case are required, data can be extracted from the list and CRFs are produced in PDF format.Results and conclusion: In this study we confirmed the applicability of our new system to post-marketing surveillance in providing prompt and efficient data exchange. We expect it to reduce the cost of data management and analysis and to improve the quality of data in post-marketing

Market Design. Evaluation of the third phase 2006-2009; Market Design. Utvaerdering av den tredje etappen 2006-2009

Energy Technology Data Exchange (ETDEWEB)

Mattsson, Carl (Global to Local Sweden AB, Raaaa (Sweden))

2009-10-15

Market Design started 2001 and has since then supported more than 50 projects. During phase III, i.e. 2006 - 2009, 18 project were supported with a total programme budget of 18 MSEK. Market Design has focused on issues related to the deregulated electricity market primarily in Sweden. The aims have been to improve the performance of the market, to develop knowledge and support research groups. The analysis in this report is limited to phase III of the programme. It is based on almost 40 interviews with stakeholders close to the programme such as the board, contractors and programme officers as well as others with thorough insight into issues of importance to the electricity market. Furthermore, a number of relevant documents related to Market Design have been analyzed. The focus of the evaluation has been to address the following issues; relevance, benefits of the programme and the projects, dissemination of results, programme administration and the achievement of programme goals. The interviews reveal that some additional issues need to be addressed further. The evaluation shows that the programme has a clearly identified role in relation to other RandD programmes. No duplicate work has been identified. The board of the programme provides a sufficient guarantee. The results of the analyses are as fellows: The interviews show that all relevant research areas have been dealt with. Nothing of significance (research areas or projects) has been omitted. The time gap between program definition and execution might require a larger budget reserve to deal with unforeseen circumstances especially in view of rapidly changing market conditions. Market Design has provided a common basis for decision making amongst governmental bodies and utilities regarding the development of the Nordic electricity market. A network of key officials working in the area, not the least the board, has been established to the benefit of regulatory aspects of market development. The value of this

Conceptual design study of fusion experimental reactor (FY86 FER)

International Nuclear Information System (INIS)

Nakashima, Kunihiko; Okano, Kunihiko; Miyamoto, Kazuhiro.

1987-09-01

This report describes the results of a conceptual study on the RF system in the typical candidates for the Fusion Experimental Reactor (FER), which were picked out through the '86FER scoping studies. According to the FER operation scenario, three RF systems, that is, ICRF (heating), LHRF (current drive and heating), ECRF (auxiliary heating) were studied. Main concern in these RF systems is the launcher, which may be so designed that required power match the geometrical constraints of the reactor. Then studies were concentrated on the launcher configuration. A prug-in concept of the launcher was adopted in each system and vacancies except transmission space were filled with water. The ICRF launcher had the 2 x 2 loop arrays antenna and the faraday shield area of 1.5 m x 1 m to provide a power of 20 MW. The LHRF launcher had the grillantenna with 28 x 8 open waveguides, and included multi junction-type power splitters which were connected to 56 transmission wave guides. The grild was designed to have two functions of current drive and heating, and provide a power of 20 MW each. The ECRF launcher had a boundle of open wave guides which a reflection mirror each, and three plain mirrors. Assuming a oscillator unit size of 200 kW, it had 40 oversized wave guides to provide a power of 3 MW. (author)

How to benefit from a common European electricity market design

International Nuclear Information System (INIS)

Ringler, Philipp; Keles, Dogan; Fichtner, Wolf

2017-01-01

The realization of an Internal Electricity Market in Europe is currently, on the one hand, progressing, in particular thanks to the wide-spread implementation of market coupling solutions for cross-border congestion management. On the other hand, diverging national market designs pose a threat to the continuation of this process. Given the challenges to electricity market design in a multi-regional context, we analyze how different design aspects, namely cross-border congestion management and capacity mechanisms, affect welfare and generation adequacy in Europe. In doing so, we rely on an agent-based simulation model for electricity wholesale markets which we apply within several numerical, computational case studies for the region of Central Western Europe (2012–2030). Our results confirm the benefits of market coupling in terms of welfare as well as generation adequacy. Furthermore, we find indications that coordinating market designs across regions supports these targets. Therefore, we recommend that European energy policy forms a stable, transparent regulatory framework with cross-border market coupling as an integral component. In this context, energy policy targets should be clearly defined and operationalized, which also needs to consider potential conflicts between them. Finally, electricity market designs need to be coordinated among states to benefit most from a common European market. - Highlights: • European electricity markets at crossroads given diverging market designs • Simulation of CWE Market Coupling using an agent-based model. • Welfare and adequacy gains from European market coupling and new interconnections. • Conflicts between energy policy targets to be considered in market design. • Coordination key to further strengthen integration of electricity markets in Europe.

The applicability of animal health surveillance systems for post-market monitoring of potential adverse effects of genetically modified (GM) feed.

Science.gov (United States)

Vince, L; Kleter, G A; Kostov, K; Pfeiffer, D U; Guitian, J

2018-04-20

A facultative post market monitoring of potential health impacts of genetically modified (GM) feedstuffs on livestock consuming these feeds after pre-market risk assessment is under ongoing consideration. Within the IPAFEED database, scientific studies on health effects beyond performance in livestock and the results of a systematic search for evidence of outcome effects due to GM feed are consolidated. These outcomes were reviewed and checked for consistency in order to identify plausible syndromes suitable for conducting surveillance. The 24 selected studies showed no consistent changes in any health parameter. There were no repeated studies in any species by GM crop type and animal species. As such, there is insufficient evidence to inform the design of surveillance systems for detecting known adverse effects. Animal health surveillance systems have been proposed for the post market monitoring of potential adverse effects in animals. Such systems were evaluated for their applicability to the detection of hypothetical adverse effects and their strengths and weaknesses to detect syndromes of concern are presented. For known adverse effects, applied controlled post-market studies may yield conclusive and high-quality evidence. For detecting unknown adverse effects, the use of existing surveillance systems may still be of interest. A simulation tool developed within the project can be adapted and applied to existing surveillance systems to explore their applicability to the detection of potential adverse effects of GM feed. Copyright © 2018. Published by Elsevier Ltd.

Market Evolution: Wholesale Electricity Market Design for 21st Century Power Systems

Energy Technology Data Exchange (ETDEWEB)

Cochran, Jaquelin [National Renewable Energy Lab. (NREL), Golden, CO (United States); Miller, Mackay [National Renewable Energy Lab. (NREL), Golden, CO (United States); Milligan, Michael [National Renewable Energy Lab. (NREL), Golden, CO (United States); Ela, Erik [National Renewable Energy Lab. (NREL), Golden, CO (United States); Arent, Douglas [National Renewable Energy Lab. (NREL), Golden, CO (United States); Bloom, Aaron [National Renewable Energy Lab. (NREL), Golden, CO (United States); Futch, Matthew [IBM, Northcastle, NY (United States); Kiviluoma, Juha [VTT Technical Research Centre of Finland, Espo (Finland); Holtinnen, Hannele [VTT Technical Research Centre of Finland, Espo (Finland); Orths, Antje [Energinet.dk (Denmark); Gomez-Lazaro, Emilio [University of Castilla-La Mancha, Real (Spain); Martin-Martinez, Sergio [University of Castilla-La Mancha, Real (Spain); Kukoda, S. [International Copper Association, New York, NY (United States); Garcia, Glycon [International Copper Association, New York, NY (United States); Mikkelsen, Kim M. [Global Green Growth Inst., Seoul (Korea); Yongqiang, Zhao [China National Renewable Energy Center, Beijing (China); Sandholt, Kaare [China National Renewable Energy Center, Beijing (China)

2013-10-01

Demand for affordable, reliable, domestically sourced, and low-carbon electricity is on the rise. This growing demand is driven in part by evolving public policy priorities, especially reducing the health and environmental impacts of electricity service and expanding energy access to under-served customers. Consequently, variable renewable energy resources comprise an increasing share ofelectricity generation globally. At the same time, new opportunities for addressing the variability of renewables are being strengthened through advances in smart grids, communications, and technologies that enable dispatchable demand response and distributed generation to extend to the mass market. A key challenge of merging these opportunities is market design -- determining how to createincentives and compensate providers justly for attributes and performance that ensure a reliable and secure grid -- in a context that fully realizes the potential of a broad array of sources of flexibility in both the wholesale power and retail markets. This report reviews the suite of wholesale power market designs in use and under consideration to ensure adequacy, security, and flexibilityin a landscape of significant variable renewable energy. It also examines considerations needed to ensure that wholesale market designs are inclusive of emerging technologies, such as demand response, distributed generation, and storage.

Design and analysis of electricity markets

Science.gov (United States)

Sioshansi, Ramteen Mehr

Restructured competitive electricity markets rely on designing market-based mechanisms which can efficiently coordinate the power system and minimize the exercise of market power. This dissertation is a series of essays which develop and analyze models of restructured electricity markets. Chapter 2 studies the incentive properties of a co-optimized market for energy and reserves that pays reserved generators their implied opportunity cost---which is the difference between their stated energy cost and the market-clearing price for energy. By analyzing the market as a competitive direct revelation mechanism we examine the properties of efficient equilibria and demonstrate that generators have incentives to shade their stated costs below actual costs. We further demonstrate that the expected energy payments of our mechanism is less than that in a disjoint market for energy only. Chapter 3 is an empirical validation of a supply function equilibrium (SFE) model. By comparing theoretically optimal supply functions and actual generation offers into the Texas spot balancing market, we show the SFE to fit the actual behavior of the largest generators in market. This not only serves to validate the model, but also demonstrates the extent to which firms exercise market power. Chapters 4 and 5 examine equity, incentive, and efficiency issues in the design of non-convex commitment auctions. We demonstrate that different near-optimal solutions to a central unit commitment problem which have similar-sized optimality gaps will generally yield vastly different energy prices and payoffs to individual generators. Although solving the mixed integer program to optimality will overcome such issues, we show that this relies on achieving optimality of the commitment---which may not be tractable for large-scale problems within the allotted timeframe. We then simulate and compare a competitive benchmark for a market with centralized and self commitment in order to bound the efficiency

[Strategy of constructing post-market integral evaluation system of traditional Chinese medicine injection].

Science.gov (United States)

Zhang, Xiao-Yu; Wang, Yan-Ping; Lin, Li-Kai; Shang, Hong-Cai; Wang, Yong-Yan

2017-08-01

As an important representative of modern Chinese medicine, traditional Chinese medicine (TCM) injzection has become an indispensable part of the Chinese medicine industry. However, its development is now restricted by the bottleneck of insufficient core competitiveness, low-level research and production, even injection quality and the safe use are not guaranteed. Thus, it is urgent to reevaluate post-marketing TCM injection generally and to make secondary development. Under current circumstances, taking major brands which have good clinical and market foundation, as well as research value, as the main subject of cultivation and evaluation is an important approach to innovative development of TCM injection industry. Unlike oral proprietary Chinese medicine, the cultivatation of major brands of TCM injection needs higher technical support, quality standards and more timely feedback. Therefore, a post-market integral evaluation system adaptive to TCM injection is required. This article discussed some key points on the construction of a post-market integral evaluation system of TCM injection in three levels： optimizing evaluation methods, building synergistic innovation platforms which combine the medical research institutions and pharmaceutical enterprises, and finally constructing the integral evaluation system. A "five to one" structure has been proposed to enhance TCM injection effectiveness, safety and adaptability on the whole, which are from the following aspects： mechanism research, clinical evidence validation, literature information mining, sustainable development of resources and industrialization operation. Copyright© by the Chinese Pharmaceutical Association.

Worldwide, 3-Year, Post-Marketing Surveillance Experience with Tofacitinib in Rheumatoid Arthritis.

Science.gov (United States)

Cohen, Stanley; Curtis, Jeffrey R; DeMasi, Ryan; Chen, Yan; Fan, Haiyun; Soonasra, Arif; Fleischmann, Roy

2018-06-01

Post-marketing surveillance (PMS) is an integral part of monitoring adverse events (AEs) following approval of new drugs. Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA). An analysis of PMS reports was conducted to evaluate the safety of tofacitinib in a post-marketing setting. Worldwide tofacitinib PMS data received in the Pfizer safety database from November 6, 2012 (first marketing authorization of tofacitinib) to November 5, 2015 were analyzed. Serious AEs (SAEs) of interest were reviewed and reporting rates (RRs) were calculated by dividing the number of SAEs by the estimated 100 patient-years of exposure. Patient exposure was calculated based on estimated worldwide sales and an estimated daily regimen of tofacitinib 5 mg twice daily. During the 3-year reporting period, worldwide post-marketing exposure to tofacitinib since approval was estimated to be 34,223 patient-years. In total, 9291 case reports (82.9% non-serious) were received and 25,417 AEs, 102 fatal cases, and 4352 SAEs were reported. The RRs (per 100 patient-years) for SAEs of interest by Medical Dictionary for Regulatory Activities System Organ Class were 2.57 for infections, 0.91 for gastrointestinal disorders, 0.60 for respiratory disorders, 0.45 for neoplasms, 0.43 for cardiac disorders, and 0.12 for hepatobiliary disorders. Although there are limitations to these data, no new safety risks were revealed in this real-world setting compared with the safety profile identified in the tofacitinib RA clinical development program. Any risks identified through the tofacitinib development program and PMS will continue to be monitored through pharmacovigilance surveillance. Pfizer Inc.

Marketing and Product Design: A Rocky Love Affair

Directory of Open Access Journals (Sweden)

Landwehr Jan R.

2015-11-01

Full Text Available The success stories of design-oriented companies like Apple, Audi or Nike have put design on the agenda in many marketing departments. Consumers cannot elude the effect of aesthetics and therefore design is a major factor for business success. Typically consumers choose the product with the best design, all other aspects being equal. Only when the interplay of product characteristics, brand and design is carefully coordinated can successful products be created. This requires an integrated approach to design, one which is applied right at the beginning of the value chain. Product development, marketing and design need to work in close cooperation, communicate well and frequently, and collect feedback from the market. Superior aesthetics are always important but should be a top priority in cases where efficiency-oriented Asian competitors are able to offer functionally similar products at much lower prices.

[Necessity of applying pharmacovigilance in post-marketing safety monitoring of traditional Chinese medicine injections].

Science.gov (United States)

Wang, Hai-Nan; Chen, Wen; Fu, Zheng; Du, Wen-min; He, Jia

2008-03-01

Traditional Chinese medicine (TCM) injection has become one of the hotspots in the new TCM research and development. The serious adverse drug reactions happened in clinical have arosed attention widely in the whole society. It's very urgent to monitor the post-marketing safety of TCM injections. This paper elucidated the pharmacovigilance's necessity in the post-marketing safety monitoring of TCM injections, basing on the reason of safety problem of TCM injections and the future developing trend of adverse drug reaction monitoring. Also, this paper introduced the rapid signal detection method of spontaneous reporting system database by data mining technology.

The Impact of Active Labour Market Policy on Post-Unemployment Outcomes

DEFF Research Database (Denmark)

Blasco, Sylvie; Rosholm, Michael

While job search theory predicts that active labour market policies (ALMPs) can affect post-unemployment outcomes, empirical evaluations investigating transition rates have mostly focused on the impact of ALMPs on exit rates from the current unemployment spell. We use a social experiment, which w......, the positive impact of the treatment becomes smaller but remains significant. 80% of the global impact of intensification acts through the direct channel for men.......While job search theory predicts that active labour market policies (ALMPs) can affect post-unemployment outcomes, empirical evaluations investigating transition rates have mostly focused on the impact of ALMPs on exit rates from the current unemployment spell. We use a social experiment, which...... was conducted in Denmark in 2005-6, to investigate the effects of a dramatic intensification of ALMPs on reemployment stability. We investigate the nature of this impact. We estimate a duration model with lagged duration dependence to separately identify "indirect" (via shorter unemployment duration...

Capacity subscription and its market design impact

International Nuclear Information System (INIS)

Doorman, Gerard; Solem, Gerd

2005-04-01

Capacity Subscription (CS) implies that consumers buy (subscribe to) a certain amount of capacity. Their demand is limited to this capacity when the total power system is short of capacity and the System Operator activates controllable Load Limiting Devices (LLDs). The objective is to maintain system security by avoiding involuntary load shedding. The report describes a market design with CS. As a case study, an analysis is made of the changes in the market design of the Nordic system that would be necessary to implement CS. First the present Nordic market design is described. Focus is on the various market participants, their roles within various time horizons and their interactions. So it is described how CS works, why it works and what is necessary to make it work. Subsequently the necessary changes in the Nordic market structure are described. The major changes are the installation of the LLDs, the establishment of the necessary infrastructure to control the LLDs and the rules governing their control and the establishment of a capacity market. The major rule is that the System Operator announces LLD activation when a shortage situation is expected. In the capacity market generators offer available capacity during system peak conditions, while consumers bid their need for capacity. Market participants are the same as on the spot market, while small consumers buy through retailer. Generators are obliged to offer the capacity sold on the capacity market on the spot market during LLD activation. Failure to do so results in a penalty payment. The report further discusses issues like the need for verification procedures, import and export, generation pooling, the handling of small consumers, reserves and a possible implementation path of CS. With respect to transmission constraints it is argued that market splitting can be a viable option. It is concluded that CS can be a possible solution to maintain generation adequacy, but there are some serious challenges. The

[Systematic review on methodology of randomized controlled trials of post-marketing Chinese patent drugs for treatment of type 2 diabetes].

Science.gov (United States)

Ma, Li-xin; Wang, Yu-yi; Li, Xin-xue; Liu, Jian-ping

2012-03-01

concealment of random numbers, 5% used placebo, 10% reported outcome attrition bias and no study employed the analysis of intention-to-treat and 98% reported the diagnostic criteria for type 2 diabetes. The participants mainly consisted of outpatients without complications (76%). The minimum and maximum sample size was 40 and 300 (106 ± 60), respectively. The inclusion and exclusion criteria and outcome measures did not match the purposes and contents of post-marketing research in the included studies. They also failed to reflect the basic principles of traditional Chinese medicine in the process of diagnosis and treatment. The demographic characteristics of the patients, the indications for medicine and the syndrome differentiation process were not reported sufficiently and transparently. In order to improve the post-marketing research and promote the rational use of Chinese patent drugs, it is recommended that phase IV clinical trials should establish clear research purpose as well as hypothesis first, and choose scientific and evidence-based study design and outcome measures. In addition, guidelines for implementation of post-marketing research should be developed.

Economics and Design of Capacity Markets for the Power Sector

OpenAIRE

Peter Cramton; Axel Ockenfels

2012-01-01

Capacity markets are a means to assure resource adequacy. The need for a capacity market stems from several market failures the most prominent of which is the absence of a robust demand-side. Limited demand response makes market clearing problematic in times of scarcity. We present the economic motivation for a capacity market, present one specific market design that utilizes the best design features from various resource adequacy approaches analyzed in the literature, and we discuss other in...

The role of power exchanges for the creation of a single European electricity market: market design and market regulation

International Nuclear Information System (INIS)

Boisseleau, F.

2004-01-01

The electricity sector worldwide is undergoing a fundamental transformation of its institutional structure as a consequence of the complex interactions of political, economic and technological forces. The way the industry is organized is changing from vertically integrated monopolies to unbundled structures that favor market mechanisms. This process in Europe, known as the liberalization process, has had a wide impact on the European electricity industry. The focus of this dissertation is an analysis of the role of electricity power exchanges in the recently liberalized electricity markets of Europe. In the context of creating a competitive electricity market at a European level, the key questions considered are the functioning of these power exchanges with respect to electricity characteristics, market design and regulatory framework. In Europe, very little attention has been paid to the role of these new marketplaces and to the issue of market design in general. Hence the main purpose of this work was to analyze how these marketplaces facilitate the trading of electricity and the role they can play in the construction of a pan-European competitive electricity market. An analysis of power exchange requires taking into account the 'double-duality' of such institutions. One, power exchanges are both a market and an institution. As a market they facilitate the trading of electricity and determine an equilibrium price. As an institution power exchanges have their own objectives and constraints, and play a role in the market design of the overall electricity market. Two, the relationship between electricity power exchanges and liberalization is neither linear nor one way: liberalization encourages the birth of such marketplaces yet marketplaces are more than the results of such process, they are also a driving force of the liberalization process. This thesis is divided into three parts. The current situation in Europe and different existing theoretical approaches in

Moving toward New Horizons for Marketing Education: Designing a Marketing Training for the Poor in Developing and Emerging Markets

Science.gov (United States)

Teklehaimanot, Mebrahtu L.; Ingenbleek, Paul T. M.; Tessema, Workneh K.; van Trijp, Hans C. M.

2017-01-01

In recent years, marketing education has broadened to poor people in developing and emerging countries. In this article, the authors use four empirical studies that apply well-established training design procedures to design a marketing training program for Ethiopian pastoralists. Because pastoralists operate in extremely remote, traditional, and…

Core designs for the de-regulated market

International Nuclear Information System (INIS)

Almberger, J.; Bernro, R.; Pettersson, H.

1999-01-01

Complete text of publication follows: The electricity market deregulation in the Nordic countries encourages innovations and cost reductions for power production in the Vattenfall reactors. The competition on the electricity market is strong, electricity price reductions dramatic and uncertainties about the future power demand is large. In the fuel area this situation has given increased attention to traditional areas like flexibility in power production, improved core designs, need for margins (improved fuel designs), improved surveillance, decreased lead times. At Vattenfall new fuel designs are already being implemented following the last fuel purchase, for which flexibility and margins, were given high values in the evaluations with the multipurpose task of eliminating fuel related problems and meeting the future market situation. This strategy has given Vattenfall a flying start to meeting the demands of the de-regulated market. What has been added are broad studies undertaken to investigate the various route into the future with respect to finding the most effective strategies for fuel and core design and optimization. In the present paper the Vattenfall priorities for fuel designs and margins are presented in a schematic manner summarizing the results of the last fuel purchase and also presenting the current program for LFAs. Technical limitations, licensing and R and D aspects, with respect to improving the fuel utilization will be mentioned. The main focus in the paper is on the broad study carried out in the PWR core design area. Driven by the relatively low power demand various possibilities for higher production flexibility have been investigated specifically extended coast-down, coast-up and yearly load follow. Further to reduce the costs for fuel consumption improvements in core designs have been studied: improved low leakage loading patterns, low enriched end zones, improved Gd designs etc. Main results and conclusions of the core design studies will

Herpes zoster vaccine live: A 10 year review of post-marketing safety experience.

Science.gov (United States)

Willis, English D; Woodward, Meredith; Brown, Elizabeth; Popmihajlov, Zoran; Saddier, Patricia; Annunziato, Paula W; Halsey, Neal A; Gershon, Anne A

2017-12-19

Zoster vaccine is a single dose live, attenuated vaccine (ZVL) indicated for individuals ≥50 years-old for the prevention of herpes zoster (HZ). Safety data from clinical trials and post-licensure studies provided reassurance that ZVL is generally safe and well tolerated. The objective of this review was to provide worldwide post-marketing safety information following 10 years of use and >34 million doses distributed. All post-marketing adverse experience (AE) reports received worldwide between 02-May-2006 and 01-May-2016 from healthcare professionals following vaccination with ZVL and submitted to the MSD AE global safety database, were analyzed. A total of 23,556 AE reports, 93% non-serious, were reported. Local injection site reactions (ISRs), with a median time-to-onset of 2 days, were the most frequently reported AEs followed by HZ. The majority of HZ reports were reported within 2 weeks of vaccination and considered, based on time-to-onset, pathogenesis of HZ, and data from clinical trials, to be caused by wild-type varicella-zoster virus (VZV). HZ confirmed by PCR analysis to be VZV Oka/Merck vaccine-strain was identified in an immunocompetent individual 8 months postvaccination and in 4 immunocompromised individuals. Disseminated HZ was reported very rarely (marketing use, was favorable and consistent with that observed in clinical trials and post-licensure studies. Copyright © 2017 Elsevier Ltd. All rights reserved.

Do societal values influence financial development? : New evidence on the effects of post materialism and institutions on stock markets

NARCIS (Netherlands)

Jordaan, J.A.; Dima, Dogdan; Goleț, Ionuț

2016-01-01

In this paper we present new evidence on the effects of social values on stock market development. Using panel data for a heterogeneous set of 43 countries, we use the Inglehart post materialism index to identify the relation between the degree of post materialism and the size of stock markets.

Economics and design of capacity markets for the power sector

Energy Technology Data Exchange (ETDEWEB)

Cramton, Peter [Maryland Univ., College Park, MD (United States). Dept. of Economics; Ockenfels, Axel [Koeln Univ. (Germany). Dept. of Economics

2012-06-15

Capacity markets are a means to assure resource adequacy. The need for a capacity market stems from several market failures the most prominent of which is the absence of a robust demand-side. Limited demand response makes market clearing problematic in times of scarcity. We present the economic motivation for a capacity market, present one specific market design that utilizes the best design features from various resource adequacy approaches analyzed in the literature, and we discuss other instruments to deal with the problems. We then discuss the suitability of the market for Europe and Germany in particular. (orig.)

Setting priorities for the evolution of the market design

International Nuclear Information System (INIS)

2001-01-01

This report, which examines the forces that will influence the evolution of the Ontario electric power market over the next 4 or 5 years, is intended for market participants and other stakeholders. It sets priorities for the next phase of market development. Some of the market rules that need more work were identified and participants and stakeholders were invited to present their comments on whether the list accurately reflects the critical market development issues that need to be addressed after market opening. The report also discusses criteria that can be used to evaluate market design changes and their relative priorities. The list of potential high priority issues include: the energy forward market; the capacity reserve market; locational marginal pricing; a capability for full assignment of physical bilateral contracts; the export of operating reserve; moving to real time bidding; encouraging dispatchability and demand side responsiveness; transmission expansion; and, introducing markets in ancillary services. This list includes the main market design issues that need to be addressed over the next several years. 1 fig., 2 tabs

Spanish generation market: structure, design and results

International Nuclear Information System (INIS)

Agosti, L.; Padilla, A. J.; Requejo, A.

2007-01-01

This paper provides an overview of the structure, design and outcome of the Spanish generation market from 1998, when the market was liberalised, to date. More precisely, this paper reviews the history of the liberalisation process; describes the structure of the generation market and its evolution over time; analyses the existence of market power; and evaluates the outcome of the liberalisation process from the viewpoint of its impact on al locative efficiency, productive efficiency and dynamic efficiency. The paper concludes with a brief summary of recent regulatory reforms. (Author)

Design and Operation of Distribution Markets

Science.gov (United States)

Parhizi, Sina

in the electricity markets, and an analytical model is presented for design and operation of such markets.

Identifying and Managing Engineering Design Requirements for Emerging Markets

DEFF Research Database (Denmark)

Li, Xuemeng

, especially for those companies originally from developed markets, to acquire an in-depth understanding of particular design requirements in emerging markets in order to adapt both company products and approaches in such contexts. Prior studies on the identification and management of design requirements have...... predominantly been conducted in the context of developed countries and relatively affluent markets. Emerging markets are distinct from developed markets in terms of numerous contextual factors, e.g., regulatory environments and competitive landscapes. These factors influence the requirement identification...... attention. There is a need for an overview of different perspectives in requirement identification for manufacturing companies and their corresponding assessments in the context of emerging markets. Therefore, this research project is motivated to 1) investigate the process of identifying and managing...

Revisiting Stock Market Integration Pre-Post Subprime Mortgage Crisis: Insight From BRIC Countries

Directory of Open Access Journals (Sweden)

Chin-Hong Puah

2015-07-01

Full Text Available This study revisits the long-run relationships and short-run dynamic causal linkages among BRIC stock market, with the particular attention to the 2008 subprime mortgage crisis. Extending related empirical studies, comparative analyses of pre-crisis, and post-crisis periods were conducted to comprehensively evaluate how stock market integration was affected by financial crises. In general, after employing cointegration test and VAR test, the results reveal the increase of stock market integration in BRICs after the subprime crisis. The evidence also found that China stock market is the most influential among the BRICs, in which China stock market has the ability to Granger cause the other three BRICs member countries. An important implication of our findings is that the degree of integration among countries tends to change over time, especially around periods marked by financial crises.

Arthritis, Rheumatism and Aging Medical Information System Post-Marketing Surveillance Program.

Science.gov (United States)

Singh, G

2001-05-01

The Arthritis, Rheumatism, and Aging Post-Marketing Surveillance Program (ARAMIS-PMS) is a collection of multicenter, prospective, noninterventional, observational longitudinal studies of patients with rheumatic diseases. The ARAMIS-PMS program aims to study patients in normal clinical setting to evaluate the real-life effectiveness, toxicity, and cost effectiveness of various medications used to treat rheumatic diseases.

An Ethical Justification for Expanding the Notion of Effectiveness in Vaccine Post-Market Monitoring: Insights from the HPV Vaccine in Canada.

Science.gov (United States)

Komparic, Ana; Smith, Maxwell J; Thompson, Alison

2016-04-01

Health regulators must carefully monitor the real-world safety and effectiveness of marketed vaccines through post-market monitoring in order to protect the public's health and promote those vaccines that best achieve public health goals. Yet, despite the fact that vaccines used in collective immunization programmes should be assessed in the context of a public health response, post-market effectiveness monitoring is often limited to assessing immunogenicity or limited programmatic features, rather than assessing effectiveness across populations. We argue that post-market monitoring ought to be expanded in two ways to reflect a 'public health notion of post-market effectiveness', which incorporates normative public health considerations: (i) effectiveness monitoring should yield higher quality data and grant special attention to underrepresented and vulnerable populations; and (ii) the scope of effectiveness should be expanded to include a consideration of the various social factors that maximize (and minimize) a vaccine's effectiveness at the population level, paying particular attention to how immunization programmes impact related health gradients. We use the case of the human papillomavirus vaccine in Canada to elucidate how expanding post-market effectiveness monitoring is necessary to close the gap between clinical practice and public health, and to ensure that vaccines are effective in a morally relevant sense.

The Visible Hand: Markets, Politics, and Regulation in Post-Katrina New Orleans

Science.gov (United States)

Jabbar, Huriya

2016-01-01

In this article Huriya Jabbar examines how the regulatory environment in post-Hurricane Katrina New Orleans has influenced choice, incentives, and competition among schools. While previous research has highlighted the mechanisms of competition and individual choice--the "invisible hand"--and the creation of markets in education, Jabbar…

Post-Cam Design and Contact Stress on Tibial Posts in Posterior-Stabilized Total Knee Prostheses: Comparison Between a Rounded and a Squared Design.

Science.gov (United States)

Watanabe, Toshifumi; Koga, Hideyuki; Horie, Masafumi; Katagiri, Hiroki; Sekiya, Ichiro; Muneta, Takeshi

2017-12-01

The post-cam mechanism in posterior stabilized (PS) prostheses plays an important role in total knee arthroplasty (TKA). The purpose of this study is to clarify the difference of the contact stress on the tibial post between a rounded post-cam design and a squared design during deep knee flexion and at hyperextension using the three-dimensional (3D) finite element models. We created 2 types of 3D, finite element models of PS prostheses (types A and B), whose surfaces were identical except for the post-cam geometries: type A has a rounded post-cam design, while type B has a squared design. Both types have a similar curved-shape intercondylar notch of the femoral component. Stress distributions, peak contact stresses, and contact areas on the tibial posts at 90°, 120°, and 150° flexion with/without 10° tibial internal rotation and at 10° hyperextension were compared between the 2 models. Type B demonstrated more concentrated stress distribution compared to type A. The peak contact stresses were similar in both groups during neutral flexion; however, the stresses were much higher in type B during flexion with 10° rotation and at hyperextension. The higher peak contact stresses corresponded to the smaller contact areas in the tibial post. A rounded post-cam design demonstrated less stress concentration during flexion with rotation and at hyperextension compared with a squared design. The results would be useful for development of implant designs and prediction of the contact stress on the tibial post in PS total knee arthroplasty. Copyright © 2017 Elsevier Inc. All rights reserved.

Serious adverse events after HPV vaccination: a critical review of randomized trials and post-marketing case series.

Science.gov (United States)

Martínez-Lavín, Manuel; Amezcua-Guerra, Luis

2017-10-01

This article critically reviews HPV vaccine serious adverse events described in pre-licensure randomized trials and in post-marketing case series. HPV vaccine randomized trials were identified in PubMed. Safety data were extracted. Post-marketing case series describing HPV immunization adverse events were reviewed. Most HPV vaccine randomized trials did not use inert placebo in the control group. Two of the largest randomized trials found significantly more severe adverse events in the tested HPV vaccine arm of the study. Compared to 2871 women receiving aluminum placebo, the group of 2881 women injected with the bivalent HPV vaccine had more deaths on follow-up (14 vs. 3, p = 0.012). Compared to 7078 girls injected with the 4-valent HPV vaccine, 7071 girls receiving the 9-valent dose had more serious systemic adverse events (3.3 vs. 2.6%, p = 0.01). For the 9-valent dose, our calculated number needed to seriously harm is 140 (95% CI, 79–653) [DOSAGE ERROR CORRECTED] . The number needed to vaccinate is 1757 (95% CI, 131 to infinity). Practically, none of the serious adverse events occurring in any arm of both studies were judged to be vaccine-related. Pre-clinical trials, post-marketing case series, and the global drug adverse reaction database (VigiBase) describe similar post-HPV immunization symptom clusters. Two of the largest randomized HPV vaccine trials unveiled more severe adverse events in the tested HPV vaccine arm of the study. Nine-valent HPV vaccine has a worrisome number needed to vaccinate/number needed to harm quotient. Pre-clinical trials and post-marketing case series describe similar post-HPV immunization symptoms.

[Establishment of model of traditional Chinese medicine injections post-marketing safety monitoring].

Science.gov (United States)

Guo, Xin-E; Zhao, Yu-Bin; Xie, Yan-Ming; Zhao, Li-Cai; Li, Yan-Feng; Hao, Zhe

2013-09-01

To establish a nurse based post-marketing safety surveillance model for traditional Chinese medicine injections (TCMIs). A TCMIs safety monitoring team and a research hospital team engaged in the research, monitoring processes, and quality control processes were established, in order to achieve comprehensive, timely, accurate and real-time access to research data, to eliminate errors in data collection. A triage system involving a study nurse, as the first point of contact, clinicians and clinical pharmacists was set up in a TCM hospital. Following the specified workflow involving labeling of TCM injections and using improved monitoring forms it was found that there were no missing reports at the ratio of error was zero. A research nurse as the first and main point of contact in post-marketing safety monitoring of TCM as part of a triage model, ensures that research data collected has the characteristics of authenticity, accuracy, timeliness, integrity, and eliminate errors during the process of data collection. Hospital based monitoring is a robust and operable process.

Sustainable design options for the German electricity market. A comparison of the energy-only market with capacity markets

International Nuclear Information System (INIS)

Keles, Dogan; Renz, Lea; Bublitz, Andreas; Zimmermann, Florian; Genoese, Massimo; Fichtner, Wolf

2016-01-01

This study intensively discusses the further developments of the electricity market design in Germany based on substantial scientific insights. For this purpose, an agent-based simulation model is applied to evaluate the operability of the energy only market extended with a strategic reserve. Furthermore, the effects of the implementation of a centralized or decentralized capacity market are analyzed.

Demand Response Within Current Electricity Wholesale Market Design

OpenAIRE

Ramos Gutierrez, Ariana Isabel; De Jonghe, Cedric; Six, Daan; Belmans, Ronnie

2013-01-01

The introduction of intermittent energy resources calls for the ability to modulate consumption patterns according to electricity availability. This paper provides a brief overview of the main electricity market design characteristics and places demand response within the framework of the existing timeline of market operation. The main differences between electricity markets lie in the price formation mechanisms where some markets pay-as- cleared and some pay- as- bid for the electricity tran...

Post-marketing research and its outcome for novel anticancer agents approved by both the FDA and EMA between 2005 and 2010: A cross-sectional study.

Science.gov (United States)

Zeitoun, Jean-David; Baron, Gabriel; Vivot, Alexandre; Atal, Ignacio; Downing, Nicholas S; Ross, Joseph S; Ravaud, Philippe

2018-01-15

Post-marketing research in oncology has rarely been described. We aimed to characterize post-marketing trials for a consistent set of anticancer agents over a long period. We performed a cross-sectional analysis of post-marketing trials registered at ClinicalTrials.gov through September 2014 for novel anticancer agents approved by both the US Food and Drug Administration and the European Medicines Agency between 2005 and 2010. All relevant post-marketing trials were classified according to indication, primary outcome, starting date, sponsors, and planned enrollment. Supplemental indications were retrieved from regulatory documents and publication rate was assessed by two different methods. Ten novel anticancer agents were eligible: five were indicated for hematologic malignancies and the remaining five for solid cancers (three for kidney cancer). We identified 2,345 post-marketing trials; 1,362 (58.1%) targeted an indication other than the originally approved one. We observed extreme variations among drugs in both number of post-marketing trials (range 8-530) and overall population to be enrolled per trial (1-8,381). Post-marketing trials assessed almost all types of cancers, the three most frequently studied cancers being leukemia, kidney cancer and myeloma. In all, 6.6% of post-marketing trials had a clinical endpoint as a primary outcome, and 35.9% and 54.1% had a safety or surrogate endpoint, respectively, as a primary outcome. Nine drugs obtained approval for supplemental indications. The publication rate at 10 years was 12.3 to 26.1% depending on the analysis method. In conclusion, we found that post-marketing research in oncology is highly heterogeneous and the publication rate of launched trials is low. © 2017 UICC.

[Expert consensus post-marketing evaluation scheme to detect immunotoxicity of Chinese medicine in clinical populations (draft version for comments)].

Science.gov (United States)

Xie, Yan-Ming; Zhao, Yu-Bin; Jiang, Jun-Jie; Chang, Yan-Peng; Zhang, Wen; Shen, Hao; Lu, Peng-Fei

2013-09-01

Through consensus, establish a post-marketing scheme and the technical processes to evaluate Chinese medicine's immunotoxicity on a population, as well as its beneficial influences on the immune system. Provide regulations on the collection, storage and transportation of serum samples. This article applies to the post-marketing scientific evaluation of the immunotoxicity of parenterally administered, and for other ways of taking Chinese medicine.

Design Alternative Evaluation No. 3: Post-Closure Ventilation

International Nuclear Information System (INIS)

Logan, R.C.

1999-01-01

The objective of this study is to provide input to the Enhanced Design Alternatives (EDA) for License Application Design Selection (LADS). Its purpose is to develop and evaluate conceptual designs for post-closure ventilation alternatives that enhance repository performance. Post-closure ventilation is expected to enhance repository performance by limiting the amount of water contacting the waste packages. Limiting the amount of water contacting the waste packages will reduce corrosion

Market design for rapid demand response

DEFF Research Database (Denmark)

Nielsen, Kurt; Tamirat, Tseganesh Wubale

We suggest a market design for rapid demand response in electricity markets. The solution consists of remotely controlled switches, meters, forecasting models as well as a flexible auction market to set prices and select endusers job by job. The auction market motivates truth-telling and makes...... it simple to involve the endusers in advance and to activate demand response immediately. The collective solution is analyzed and economic simulations are conducted for the case of Kenya. Kenya has been su ering from unreliable electricity supply for many years and companies and households have learned...... to adjust by investments in backup generators. We focus on turning the many private backup generators into a demand response system. The economic simulation focuses on possible distortion introduced by various ways of splitting the generated surplus from the demand response system. An auction run instantly...

Hybrid Electricity Markets with Long-Term Risk-Sharing Arrangements: Adapting Market Design to Security of Supply and decarbonization Objectives

International Nuclear Information System (INIS)

ROQUES, Fabien; FINON, Dominique

2017-01-01

The re-emergence of policy interventionism in electricity markets raises questions as to how market design can best be adapted to meeting the investment challenge associated with security of supply (SoS) and decarbonization objectives. This paper takes an institutionalist approach in terms of modularity of the market design, and reviews the standard historical approach towards competitive markets, in order to analyse the roles and interactions of the initial and additional market 'modules'. We argue that a number of additional modules is required to achieve long-term policy objectives, such as decarbonization and security of supply (SoS). But, in turn, they destabilise the initial modules of the market design, in particular by the entries of renewables. We review the international experience with hybrid market design and draw a number of policy recommendations at to best practices, as well as suggesting ways in which the initial market modules can be improved to prevent inconsistencies with the new modules. The move towards a hybrid market regime, which relies on a combination of planning, long-term risk sharing arrangements and improved markets entrenched in a function of short-term coordination, appears to be unavoidable where decarbonization policies are adopted. (authors)

Linking Design, Marketing, and Innovation: Managing the Connection for Competitive Advantage

OpenAIRE

Dr. Yen Hsu

2012-01-01

Marketing should closely coordinate with product innovation. Not only will an effective connection of the marketing activity and design trigger product innovation in enterprises, it is a key factor to the product success in the market place. In practice, how to process product design so as to reach the goal of marketing during the innovation procedure? In the past, enterprises did have some concrete actions but empirical studies regarding the correlation model between marketing strategy and d...

Customer Relationship within the Furniture Design Market : A qualitative study of how companies within the furniture design market relate to the challenges connected to customer loyalty

OpenAIRE

Wahlström, Marie-Louise; Bergström, Jenny

2010-01-01

Background: The customer relationship is becoming more important for companies within the Swedish furniture design industry due to competition for market shares. The market is getting more crammed while the interest for furniture design amongst people is increasing, therefore furniture design companies need to find effective ways to attract loyal customers. Research has been made to show the importance of collaboration between companies and this is something that can increase the market share...

76 FR 41238 - Post Rock Wind Power Project, LLC; Supplemental Notice That Initial Market-Based Rate Filing...

Science.gov (United States)

2011-07-13

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. ER11-3959-000] Post Rock Wind Power Project, LLC; Supplemental Notice That Initial Market-Based Rate Filing Includes Request for... Rock Wind Power Project, LLC's application for market-based rate authority, with an accompanying rate...

Resilient design in the conservation of Johar market heritage building

Science.gov (United States)

Roesmanto, Totok

2017-12-01

Johar Market building based on Law of Repubic of Indonesia No.11 of 2010 is a heritage building. It was built in 1936 located near traditional square of Pasebaan and Aloon- Aloon was built by Dutch merchants union in 1678. Semarang based on decentralized policy by the Dutch Government in 1906 became a trading city. Rapid development of trading activities has caused the city planning policy by Semarang Government since 1970 made Aloon-Aloon become market buildings. Johar Market and market buildings in surrounding were on fire in 2015. Basing on Law No.11 of 2010 Semarang Government plans to conserve Johar Market heritage building and reconstruct Aloon-Aloon based on proposal of Roesmanto in 2016. The architect bureau assigned by the Semarang Government designed a new building in the middle of South-Johar Market to accommodate Johar merchants. This study aims to evaluate the design of new building by the architect bureau considering that since 2012 the city of Semarang including earthquake prone areas. The revitalization of Johar Market should use resilient design in order to prevent future damages to heritage buildings located nearby and new building must be spaced sufficiently against surrounding heritage buildings. This research uses descriptive qualitative method base on the field data after Johar Market burned and design planned bureau architect. The results of this study found that the distance between new building and heritage building is less wide.

The evolving design of RTO ancillary service markets

International Nuclear Information System (INIS)

Isemonger, Alan G.

2009-01-01

Although the markets for ancillary services at the North American Independent System Operators are often structured in quite different ways there is an emerging set of core design elements that represent a rough consensus as to what the optimal design configuration for ancillary services should be, albeit with some regional variation. This paper looks back at how the design of ancillary services markets has recently evolved to put this development in context. Thereafter it examines the methods by which ancillary services are procured by highlighting the procurement practices at a number of different Independent System Operators, principally those in California, New York, New England, Texas and the PJM Interconnection, in an attempt to tease out the remaining reasons why the ancillary service markets are still so different. This is important as there are many innovations that are not rooted in regional differences but reflect genuine technical advances and economic efficiency gains and can be replicated across other ISOs to produce more efficient designs, greater reliability and lower costs. (author)

Eco-marketing and eco-design of products

Directory of Open Access Journals (Sweden)

Filipović Jovan

2007-01-01

Full Text Available Environmental marketing (Eco-marketing, as a relatively new movement, emerged at the beginning of the 20th century, is in the growing phase of its development. Eco-labeling and other ways/types of eco-marketing are attracting more attention of consumers, since they are aware of the necessity of nature conservation and environmental protection. There has been a lot of misunderstanding and miss leadings in interpretation and substantiation of ecomarketing claims in previous period of time. One of the most concrete improvements in eco-marketing was appearance and establishment of ISO 14020 guidelines. ISO 14020 guidelines are integral part of ISO 14000 series of standards, which could be implemented in eco-marketing. At the same time, development of "green" products and marketing of "green" products, are direct positive contributions to resources reduction, environmental protection and sustainable economic development. Companies designing this kind of products can expect better position on the market, improvement of competitiveness, reduction of expenses (less raw materials, less waste, less harmful effects on the environment, raising corporate social responsibility, higher export.

Electricity market design of the future; Strommarktdesign der Zukunft

Energy Technology Data Exchange (ETDEWEB)

Peek, Markus; Diels, Robert [r2b energy consulting GmbH, Koeln (Germany)

2016-02-15

The transformation of the power generation system, to one in which renewable energies will form a cornerstone, will change the requirements for all market actors. To achieve the goals of the German Energiewende ('energy transition'), greater flexibility in production and consumption is of particular importance. Flexibility enables the cost-effective integration of the fluctuating actual feed-in of renewable energies. On the one hand, the technical options for reducing existing technical inflexibilities are given to a considerable extent. On the other hand, analyses of the transnational compensation effects of load and renewable energy supply (RES) feed-in show that flexibility requirements can be reduced significantly in a common electricity market. Electricity markets in which there is open technological competition are an appropriate instrument for the flexibilization of the power supply system. In the short term, the mechanisms of competitive electricity markets ensure an efficient synchronization of supply and demand. Over the medium and long term, the market creates efficient incentives to adapt the generation system and the behavior of consumers to future needs, resulting from the changes in the residual load structure. But at the same time, in recent years the occurrence of negative electricity prices in situations with significantly positive residual loads show that flexibility restraints exist. The causes of these restraints are at least partly due to the market design or the regulatory framework. On the one hand, there are barriers to market entry and, on the other hand, price signals from the electricity markets do not reach all market actors or reach them distortedly. To enable the cost effective development of the different flexibility options in an open technology competition, restraints resulting from market design and the regulatory framework (e. g. in the framework of grid charges, the market and product design of control power markets

Game design as marketing: How game mechanics create demand for virtual goods

Directory of Open Access Journals (Sweden)

Lehdonvirta, V.

2010-01-01

Full Text Available Selling virtual goods for real money is an increasingly popular revenue model for massively-multiplayer online games (MMOs, social networking sites (SNSs and other online hangouts. In this paper, we argue that the marketing of virtual goods currently falls short of what it could be. Game developers have long created compelling game designs, but having to market virtual goods to players is a relatively new situation to them. Professional marketers, on the other hand, tend to overlook the internal design of games and hangouts and focus on marketing the services as a whole. To begin bridging the gap, we propose that the design patterns and game mechanics commonly used in games and online hangouts should be viewed as a set of marketing techniques designed to sell virtual goods. Based on a review of a number of MMOs, we describe some of the most common patterns and game mechanics and show how their effects can be explained in terms of analogous techniques from marketing science. The results provide a new perspective to game design with interesting implications to developers. Moreover, they also suggest a radically new perspective to marketers of ordinary goods and services: viewing marketing as a form of game design.

Combined cycle design flexibility in today's market

International Nuclear Information System (INIS)

DeRidder, W.N.; Knott, S.J.

1995-01-01

In the power generation industry, non utility generators (NUG's) comprise a significant portion of new generation growth as electricity demands exceed existing utility capacities. These NUG's are developed by customers with widely varying experiences; bankers, lawyers, architect engineers, original equipment manufacturers, and other organizations involved in such diverse industries as petrochemical, pulp and paper, and steel making. The demands of these customers can be significantly varied in terms of features such as capacity factor, operability, maintainability, equipment redundancy, acceptable design practices, and many others. In addition, both the utility and NUG industries demand flexibility due to external influences such as regulatory policies, environmental conditions new design technologies, and emerging global markets. All of these factors are subject to wide variation across different market regions and even within a given region. This paper discusses the development of a reference plant design approach which focuses on customer flexibility while maximizing the use of proven designs. This approach allows basic system designs to be modified in a modular fashion to meet the differing demands of utility and NUG customers

Mobile electronic versus paper case report forms in clinical trials: a randomized controlled trial.

Science.gov (United States)

Fleischmann, Robert; Decker, Anne-Marie; Kraft, Antje; Mai, Knut; Schmidt, Sein

2017-12-01

Regulations, study design complexity and amounts of collected and shared data in clinical trials render efficient data handling procedures inevitable. Recent research suggests that electronic data capture can be key in this context but evidence is insufficient. This randomized controlled parallel group study tested the hypothesis that time efficiency is superior when electronic (eCRF) instead of paper case report forms (pCRF) are used for data collection. We additionally investigated predictors of time saving effects and data integrity. This study was conducted on top of a clinical weight loss trial performed at a clinical research facility over six months. All study nurses and patients participating in the clinical trial were eligible to participate and randomly allocated to enter cross-sectional data obtained during routine visits either through pCRF or eCRF. A balanced randomization list was generated before enrolment commenced. 90 and 30 records were gathered for the time that 27 patients and 2 study nurses required to report 2025 and 2037 field values, respectively. The primary hypothesis, that eCRF use is faster than pCRF use, was tested by a two-tailed t-test. Analysis of variance and covariance were used to evaluate predictors of entry performance. Data integrity was evaluated by descriptive statistics. All randomized patients were included in the study (eCRF group n = 13, pCRF group n = 14). eCRF, as compared to pCRF, data collection was associated with significant time savings  across all conditions (8.29 ± 5.15 min vs. 10.54 ± 6.98 min, p = .047). This effect was not defined by participant type, i.e. patients or study nurses (F (1,112)  = .15, p = .699), CRF length (F (2,112)  = .49, p = .609) or patient age (Beta = .09, p = .534). Additional 5.16 ± 2.83 min per CRF were saved with eCRFs due to data transcription redundancy when patients answered questionnaires directly in eCRFs. Data integrity was

Reliability and standard market design : a square plug and a round socket, the fundamental flaw of the market design

International Nuclear Information System (INIS)

Bekman, K.

2003-01-01

A electricity power system is designed and built to deliver reliable power supplies. A failure of a single component should not lead to the failure of the entire system. Oversupply results in prices at marginal cost of production, inadequate return on capital investment and economic failure of supplies. Uneconomic sources of supply would pull out in cases of oversupply. Competitive markets need flexible supply and demand and scarcity pricing in order to promote new investment. The problem with such a scenario is that scarcity reduces the level of reliability. An oversupply, while ensuring reliability, offers an inadequate return on capital. This presentation included several graphs depicting results of market failure with reference to NYMEX analysis of credit quality, NEPOOL summer capacity 2001, NYS summer capacity 2001, and PJM summer capacity 2001. A graph illustrating a New England 2002 load duration curve and its analysis was also included. According to the author, the market design is flawed because it does not pay for reliability. It fails to compensate generation for capital at risk, and it fails to address the fact that nearly half of the capacity supplies less than 10 per cent energy. He notes that the liquidity crisis will continue and grow unless changes are made and new entrants come into the market. 8 figs

The Nature and Design of Post-Industrial Organizations

OpenAIRE

George P. Huber

1984-01-01

This paper describes the nature and design of post-industrial organizations. It begins with an assessment of the popular literature on post-industrial society, and finds that this literature is an inappropriate basis for inferring the nature of post-industrial organizations. Partly as a consequence of this finding, the paper turns to systems theory as a basis for determining both the nature of post-industrial society and the nature of the increased demands that this environment would impose o...

Comparison of Group-Buying Online Auction and Posted Pricing Mechanism in an Uncertain Market

Institute of Scientific and Technical Information of China (English)

CHEN Jian; LIU Yunhui; SONG Xiping

2004-01-01

Demand uncertainty is a key factor for the seller's decision making, especially in the e-business environment, for the website to sell products through the online auction. In this paper, two kinds of demand uncertainties are considered: the consumer regime uncertainty and the inherent randomness of the market environment. Then, how to use a novel business model and group-buying auction (GBA) is analyzed in such a market environment. Based on the comparison of the GBA and the posted price mechanism, some conditions that favor the GBA are provided.

Market Segmentation and Conjoint Analysis for Apple Family Design

OpenAIRE

Abbas Al-Refaie; Nour Bata

2016-01-01

A distributor of Apple products' experiences numerous difficulties in developing marketing strategies for new and existing mobile product entries that maximize customer satisfaction and the firm's profitability. This research, therefore, integrates market segmentation in platform-based product family design and conjoint analysis to identify iSystem combinations that increase customer satisfaction and business profits. First, the enhanced market segmentation grid is created. Then, the estimate...

[Process and key points of clinical literature evaluation of post-marketing traditional Chinese medicine].

Science.gov (United States)

Liu, Huan; Xie, Yanming

2011-10-01

The clinical literature evaluation of the post-marketing traditional Chinese medicine is a comprehensive evaluation by the comprehensive gain, analysis of the drug, literature of drug efficacy, safety, economy, based on the literature evidence and is part of the evaluation of evidence-based medicine. The literature evaluation in the post-marketing Chinese medicine clinical evaluation is in the foundation and the key position. Through the literature evaluation, it can fully grasp the information, grasp listed drug variety of traditional Chinese medicines second development orientation, make clear further clinical indications, perfect the medicines, etc. This paper discusses the main steps and emphasis of the clinical literature evaluation. Emphasizing security literature evaluation should attach importance to the security of a comprehensive collection drug information. Safety assessment should notice traditional Chinese medicine validity evaluation in improving syndrome, improveing the living quality of patients with special advantage. The economics literature evaluation should pay attention to reliability, sensitivity and practicability of the conclusion.

The Consumer’s Experience of Design Influences How Markets Work

DEFF Research Database (Denmark)

Gabrielsen, Gorm; Kristensen, Tore

2016-01-01

Most studies in marketing operate at a market level, which also becomes frequently the condition for design work. This means that the aggregate or weighted average consumer is the focus. Having already made this aggregation as the “top-down approach” indicates, it is not feasible to take...... the consequences at a market level. We explore a procedure that enables the marketer to estimate the effect of a marketing message like a mission statement in a logo at the level of a single individual. This is a prior to market test, with its own realism. The procedure can easily be extended to products, where...... the trace of the individual. In the bottom up approach we measure how much the influence of a treatment like that of facing a particular design influences each human being. Successively, one may see if other behavioural characteristics also unite for instance those who are heavily affected or those who...

[Importance of Post-Marketing Studies in Gathering of Clinical Evidences for Proper Usage of Anti-Cancer Drugs, and the StudyRequirements for Their Credibility].

Science.gov (United States)

Inagaki, Osamu

2016-04-01

Pharmaceutical companies recognize the importance of post-marketing studies because they are crucial in the generation of clinical evidences for the usage of new medicines. To generate clinical evidences, quality of post-marketing studies should be well controlled from view point of "ethical conduction" and "reliability of results". In addition, control of conflict of interest (COI) between researchers and industries is also indispensable and is requested for the transparency of the studies. Japan Pharmaceutical Manufacturers Association(JPMA)stresses its commitment to the progressof transparency in post-marketing studies.

New Brunswick Market Design Committee : final report

International Nuclear Information System (INIS)

2002-04-01

This report presents a plan for implementing New Brunswick's electricity restructuring. It includes two resolutions and 95 recommendations to help achieve the main policy objectives of the White Paper, the New Brunswick Energy Policy. The most significant policy goal outlined in the White Paper is the restructuring of the electricity sector, with initial competition being only at the wholesale and large industrial retail level. The Board of Commissioners of Public Utilities will regulate many aspects of the new electricity market. In addition, green pricing options will be made available. The Market Design Committee recommends that the government set up a bilateral contract market for wholesale and large industrial customers to contract with alternate providers for electrical power. Power generators would have the freedom to sell by contract to customers both within and outside the province. The report describes the requirements for establishing a bilateral contract market and how it functions. The Committee also recommends designating a Heritage Pool of electricity available from the existing generation assets in the province. Other recommendations include the creation of programs that will help meet environmental protection goals. The programs include net metering, support of embedded generation, renewable portfolio standards, energy efficiency programs, green pricing, broad-based carbon dioxide emissions trading, emission performance standards, and the promotion of cogeneration. 37 refs., 2 figs

Using forward markets to improve electricity market design

International Nuclear Information System (INIS)

Ausubel, Lawrence M.; Cramton, Peter

2010-01-01

Forward markets, both medium term and long term, complement the spot market for wholesale electricity. The forward markets reduce risk, mitigate market power, and coordinate new investment. In the medium term, a forward energy market lets suppliers and demanders lock in energy prices and quantities for one to three years. In the long term, a forward reliability market assures adequate resources are available when they are needed most. The forward markets reduce risk for both sides of the market, since they reduce the quantity of energy that trades at the more volatile spot price. Spot market power is mitigated by putting suppliers and demanders in a more balanced position at the time of the spot market. The markets also reduce transaction costs and improve liquidity and transparency. Recent innovations to the Colombia market illustrate the basic elements of the forward markets and their beneficial role. (author)

Using forward markets to improve electricity market design

Energy Technology Data Exchange (ETDEWEB)

Ausubel, Lawrence M.; Cramton, Peter [University of Maryland, College Park, MD 20742 (United States)

2010-12-15

Forward markets, both medium term and long term, complement the spot market for wholesale electricity. The forward markets reduce risk, mitigate market power, and coordinate new investment. In the medium term, a forward energy market lets suppliers and demanders lock in energy prices and quantities for one to three years. In the long term, a forward reliability market assures adequate resources are available when they are needed most. The forward markets reduce risk for both sides of the market, since they reduce the quantity of energy that trades at the more volatile spot price. Spot market power is mitigated by putting suppliers and demanders in a more balanced position at the time of the spot market. The markets also reduce transaction costs and improve liquidity and transparency. Recent innovations to the Colombia market illustrate the basic elements of the forward markets and their beneficial role. (author)

The German electricity market. Does the present market design provide security of supply?

International Nuclear Information System (INIS)

Janssen, Matthias; Peichert, Patrick; Perner, Jens; Riechmann, Christoph; Niedrig, Thomas

2014-01-01

A heated discussion is being waged in Germany and large parts of Europe over the introduction of what are referred to as capacity mechanisms, whose purpose is to provide security of supply in the electricity sector. In this context two consulting firms have undertaken a both qualitative and quantitative study of the fitness of the present market design, which is based on the ''Energy-Only Market'' (EOM), to provide security of supply in the German electricity market. The authors come to the conclusion that, if suitably framed, the EOM can continue to provide a secure electricity supply in accordance with consumer preferences and at the lowest possible cost.

New Brunswick Market Design Committee : Congestion management issues

International Nuclear Information System (INIS)

2001-01-01

The restructuring of the New Brunswick wholesale power market comprises a number of issues that need to be resolved concerning transmission system related policy decisions and detailed design issues. The wholesale market structure, ownership structure, and means of preventing market power abuses all have an impact on the resolution of many of those issues. Some transmission related decisions regarding congestion management must be made, and they are examined in this document. The report includes a discussion of the issues related to congestion on the transmission system, a review of the decisions that remain to be made while proposing a number of alternatives, reviews decisions that other jurisdictions have made in somewhat similar circumstances. Finally, the advantages and disadvantages of each alternative are identified. Several high level transmission tariff design issues requiring to be addressed later in greater detail are listed in this document. 1 tab

Review of Post-Marketing Safety Data on Tapentadol, a Centrally Acting Analgesic.

Science.gov (United States)

Stollenwerk, Ariane; Sohns, Melanie; Heisig, Fabian; Elling, Christian; von Zabern, Detlef

2018-01-01

Tapentadol is a centrally acting analgesic that has been available for the management of acute and chronic pain in routine clinical practice since 2009. This is the first integrated descriptive analysis of post-marketing safety data following the use of tapentadol in a broad range of pain conditions relating to the topics overall safety, dose administration above approved dosages, administration during pregnancy, serotonin syndrome, respiratory depression, and convulsion. The data analyzed pertain to spontaneous reports from healthcare and non-healthcare professionals and were put in the context of safety information known from interventional and non-interventional trials. The first years of routine clinical practice experience with tapentadol have confirmed the tolerability profile that emerged from the clinical trials. Moreover, the reporting of expected side effects such as respiratory depression and convulsion was low and no major risks were identified. The evaluation of available post-marketing data did not confirm the theoretical risk of serotonin syndrome nor did it reveal unexpected side effects with administration of higher than recommended doses. More than 8 years after its first introduction, the favorable overall safety profile of tapentadol in the treatment of various pain conditions is maintained in the general population. Grünenthal GmbH.

Teaching User-Centered Design in New Product Marketing

Science.gov (United States)

Love, Edwin; Stone, Donn E.; Wilton, Taine

2011-01-01

Thanks in part to groundbreaking work by companies such as Apple and IDEO, there has been growing interest in design as a way to improve the odds of new product success. This paper describes a user-centered design workshop developed for a new product marketing course. The workshop included exercises designed to explain and illustrate the…

Romanticizing the Market

DEFF Research Database (Denmark)

Johnsen, Christian Garmann

2016-01-01

is echoed in post-bureaucratic management literature. Comparing Rousseau's romanticization of nature with what I call the romanticization of markets, I show how the post-bureaucratic management literature employs the logic of market rationalism to generate a managerial pedagogy that installs the market...

Information seeking-pattern of Nigerian textile market women and ...

African Journals Online (AJOL)

The study investigated the information seeking-pattern of Nigerian textile market women and strategies for improvement of which the study was an ex-post-facto type and adopted survey research design. Disproportional stratified random technique was used to select markets for the study while questionnaire was used to ...

Report on IPPSO Market Design Workshops, May 26, 1998

International Nuclear Information System (INIS)

1998-01-01

Reports of each of the five break-out group sessions each one dealing with one of the following issues of (1) transitional issues, (2) reserve, peak and new load capacity, (3) congestion management, (4) renewables and environmental issues, and (5) stranded debt and vesting, were summarized. The reports summarized the discussions, and consensus decisions reached during the sessions. Common themes that emerged during each of the group's deliberation included recognition of the complexity of issues before the Market Design Committee (MDC), the need for flexibility, the need for a level playing field, the critical nature of the transparency of information for investment decision making, the necessity of managing and regulating Ontario Hydro's market power to ensure the viability of a competitive market and to minimize abuses of the corporation's existing monopoly position, broad support for a vibrant renewable energy industry and for enshrining the protection of the environment in the design of the new market

A post-marketing safety and efficacy assessment of a monoclonal antibody purified high-purity factor VIII concentrate.

Science.gov (United States)

Hay, C R; Lee, C A; Savidge, G

1996-01-01

The identification of infrequent side-effects of clotting factor concentrates, undetected by clinical trials, is facilitated by post-marketing surveillance. We present a post-marketing surveillance study in which 97 patients with haemophilia A, attending three haemophilia centres, were treated over a median follow-up period of 284 days (range 1-1074), and a total follow-up period of 30,080 days, with a pasteurized immunoaffinity purified factor VIII concentrate (Monoclate-P, Armour, Collegeville, USA). 5216 infusions, using 10,527,000 units of Monoclate-P, were carried out, mostly for routine haemarthroses or prophylaxis. No new inhibitors were observed during the study. At the start of the study 60/97 were HIV seropositive, 67/97 HBs antibody positive, 12 HbsAb negative and the remainder HBsAb positive before the study period. 13/14 tested were HAV seropositive at the beginning of the study. One patient became HAV seropositive during the study period, an infection thought to be community acquired. No other seroconversions were observed. Only one mild transfusion reaction was observed. This study confirms the safety and efficacy of Monoclate-P. Post-marketing surveillance or nationally organized pharmaco-vigilance should be practiced more widely to enable identification of low-frequency side-effects of treatment.

Two-Sided Matching Agents for Electronic Employment Market Design: Social Welfare Implications

National Research Council Canada - National Science Library

Gates, William

2002-01-01

... employment market designs. Using a quasi-price measure for comparison and examining social welfare as a basis for assessing market-design alternatives, we provide novel insight into the balance required between technologically...

How to Shape Markets Through Design Elements Such as Logos?

DEFF Research Database (Denmark)

Kristensen, Tore; Gabrielsen, Gorm

In this paper, we use logo design as means of showing how variation it the consumer’s perceptions can influence the effectiveness of a market. It is often assumed that consumers perceive the same message when they explore options in a market. If they actually see different things in a logo, like ...... the effectiveness of communication through the market....

[Establish research model of post-marketing clinical safety evaluation for Chinese patent medicine].

Science.gov (United States)

Zheng, Wen-ke; Liu, Zhi; Lei, Xiang; Tian, Ran; Zheng, Rui; Li, Nan; Ren, Jing-tian; Du, Xiao-xi; Shang, Hong-cai

2015-09-01

The safety of Chinese patent medicine has become a focus of social. It is necessary to carry out work on post-marketing clinical safety evaluation for Chinese patent medicine. However, there have no criterions to guide the related research, it is urgent to set up a model and method to guide the practice for related research. According to a series of clinical research, we put forward some views, which contained clear and definite the objective and content of clinical safety evaluation, the work flow should be determined, make a list of items for safety evaluation project, and put forward the three level classification of risk control. We set up a model of post-marketing clinical safety evaluation for Chinese patent medicine. Based this model, the list of items can be used for ranking medicine risks, and then take steps for different risks, aims to lower the app:ds:risksrisk level. At last, the medicine can be managed by five steps in sequence. The five steps are, collect risk signal, risk recognition, risk assessment, risk management, and aftereffect assessment. We hope to provide new ideas for the future research.

Post processing of Design Load Cases using Pdap

DEFF Research Database (Denmark)

Pedersen, Mads Mølgaard

Pdap provides functions for post-processing and documentation of a set of hawc2 result files, e.g. a full design load case. This report describes the input and its syntax, the mathematical foundation and the output in terms of statistic files and standard reports.......Pdap provides functions for post-processing and documentation of a set of hawc2 result files, e.g. a full design load case. This report describes the input and its syntax, the mathematical foundation and the output in terms of statistic files and standard reports....

On the Market Aspect of Product Program Design: Towards a Definition of an Architecture of the Market

DEFF Research Database (Denmark)

Hansen, Christian Lindschou; Mortensen, Niels Henrik; Hvam, Lars

2012-01-01

an architecture of the market. This is to be interpreted as the ‘market perspective’ of the product family referring to the design of the product family from the market’s point of view. The main result of this paper is the suggestion of a definition of a market architecture with an articulation of its elements...

[Three-dimensional computer aided design for individualized post-and-core restoration].

Science.gov (United States)

Gu, Xiao-yu; Wang, Ya-ping; Wang, Yong; Lü, Pei-jun

2009-10-01

To develop a method of three-dimensional computer aided design (CAD) of post-and-core restoration. Two plaster casts with extracted natural teeth were used in this study. The extracted teeth were prepared and scanned using tomography method to obtain three-dimensional digitalized models. According to the basic rules of post-and-core design, posts, cores and cavity surfaces of the teeth were designed using the tools for processing point clouds, curves and surfaces on the forward engineering software of Tanglong prosthodontic system. Then three-dimensional figures of the final restorations were corrected according to the configurations of anterior teeth, premolars and molars respectively. Computer aided design of 14 post-and-core restorations were finished, and good fitness between the restoration and the three-dimensional digital models were obtained. Appropriate retention forms and enough spaces for the full crown restorations can be obtained through this method. The CAD of three-dimensional figures of the post-and-core restorations can fulfill clinical requirements. Therefore they can be used in computer-aided manufacture (CAM) of post-and-core restorations.

Marketing and product design: a rocky love affair

OpenAIRE

Landwehr, Jan Rüdiger; Herrmann, Andreas

2015-01-01

The success stories of design-oriented companies like Apple, Audi or Nike have put design on the agenda in many marketing departments. Consumers cannot elude the effect of aesthetics and therefore design is a major factor for business success. Typically consumers choose the product with the best design, all other aspects being equal. Only when the interplay of product characteristics, brand and design is carefully coordinated can successful products be created. This requires an integrated app...

A distributed research network model for post-marketing safety studies: the Meningococcal Vaccine Study.

Science.gov (United States)

Velentgas, Priscilla; Bohn, Rhonda L; Brown, Jeffrey S; Chan, K Arnold; Gladowski, Patricia; Holick, Crystal N; Kramer, Judith M; Nakasato, Cynthia; Spettell, Claire M; Walker, Alexander M; Zhang, Fang; Platt, Richard

2008-12-01

We describe a multi-center post-marketing safety study that uses distributed data methods to minimize the need for covered entities to share protected health information (PHI). Implementation has addressed several issues relevant to creation of a large scale post-marketing drug safety surveillance system envisioned by the FDA's Sentinel Initiative. This retrospective cohort study of Guillain-Barré syndrome (GBS) following meningococcal conjugate vaccination incorporates the data and analytic expertise of five research organizations closely affiliated with US health insurers. The study uses administrative claims data, plus review of full text medical records to adjudicate the status of individuals with a diagnosis code for GBS (ICD9 357.0). A distributed network approach is used to create the analysis files and to perform most aspects of the analysis, allowing nearly all of the data to remain behind institutional firewalls. Pooled analysis files transferred to a central site will contain one record per person for approximately 0.2% of the study population, and contain PHI limited to the month and year of GBS onset for cases or the index date for matched controls. The first planned data extraction identified over 9 million eligible adolescents in the target age range of 11-21 years. They contributed an average of 14 months of eligible time on study over 27 months of calendar time. MCV4 vaccination coverage levels exceeded 20% among 17-18-year olds and 16% among 11-13 and 14-16-year-old age groups by the second quarter of 2007. This study demonstrates the feasibility of using a distributed data network approach to perform large scale post-marketing safety analyses and is scalable to include additional organizations and data sources. We believe these results can inform the development of a large national surveillance system. Copyright (c) 2008 John Wiley & Sons, Ltd.

Designing Online Marketplace To Resolve Marketing Problem For Small and Medium Enterprises (SMEs

Directory of Open Access Journals (Sweden)

Aditya Hermawan

2017-03-01

Full Text Available The study aims to design an online marketplace to provide solutions to problems faced by Small and Medium Enterprises (SMEs, the difficulty to market their products online. One of the problems faced by SMEs is difficult to market their products online. One of the solutions that we provide is by designing an online marketplace to solve marketing problems effectively. We found that SMEs have attempted to market their products through social media such as facebook, twitter and others. In addition, some SMEs also have a website and advertise their products through online advertising. However, many of those who did not know how to market products online in order to increase sales. We designed an online marketplace for SMEs based on the concept of e-commerce to resolve the problems faced by SMEs, the effective marketing. The online market design is made taking into account the needs of SMEs as well as customer needs. Therefore, this study was conducted to SMEs in Malang, East Java, Indonesia  and the people who often make purchases online.With the existence of the online market, SMEs can increase sales lead to increased profits for SMEs. Keyword: Online market, E-Commerce, Maketing

Market Design for Rapid Demand Response - The Case of Kenya

OpenAIRE

Kurt Nielsen; Tseganesh Wubale Tamirat

2014-01-01

We suggest a market design for rapid demand response in electricity markets. The solution consists of remotely controlled switches, meters, forecasting models as well as a flexible auction market to set prices and select endusers job by job. The auction market motivates truth-telling and makes it simple to involve the endusers in advance and to activate demand response immediately. The collective solution is analyzed and economic simulations are conducted for the case of Kenya. Kenya has been...

Agora Energiewende (2016). The power market pentagon. A pragmatic power market design for Europe's energy transition

Energy Technology Data Exchange (ETDEWEB)

Buck, Matthias; Redl, Christian; Steigenberger, Markus; Graichen, Patrick

2016-04-15

As consequence of Europe's climate and energy agenda, the European Union will generate some 50 percent of its electricity from renewables by 2030. By 2050, the EU's power system will have to be completely carbon-free. Solar photovoltaics and wind power - driven by significant cost reductions - will almost certainly contribute the biggest share of the zero-carbon technologies. Given the specific characteristics of wind power and photovoltaics (intermittent generation, high capital costs, very low variable costs), they will fundamentally change both market operations and the market design framework. Decarbonisation rests on continuous investments in these technologies. Usually it is expected that the energy market will deliver these investments, in combination with the emissions trading system. But is this view, based on simple textbook economics, enough to enable the required investments under real world conditions? In this paper, we argue that this rather theoretical view to power market design is not the way forward. Instead, a more pragmatic approach is needed, that takes into account the complex practical, political, and economic challenges of the transition towards a carbon-free power system. Thus, we propose to think of the future European market design as a Power Market Pentagon.

Agora Energiewende (2016). The power market pentagon. A pragmatic power market design for Europe's energy transition

International Nuclear Information System (INIS)

Buck, Matthias; Redl, Christian; Steigenberger, Markus; Graichen, Patrick

2016-01-01

As consequence of Europe's climate and energy agenda, the European Union will generate some 50 percent of its electricity from renewables by 2030. By 2050, the EU's power system will have to be completely carbon-free. Solar photovoltaics and wind power - driven by significant cost reductions - will almost certainly contribute the biggest share of the zero-carbon technologies. Given the specific characteristics of wind power and photovoltaics (intermittent generation, high capital costs, very low variable costs), they will fundamentally change both market operations and the market design framework. Decarbonisation rests on continuous investments in these technologies. Usually it is expected that the energy market will deliver these investments, in combination with the emissions trading system. But is this view, based on simple textbook economics, enough to enable the required investments under real world conditions? In this paper, we argue that this rather theoretical view to power market design is not the way forward. Instead, a more pragmatic approach is needed, that takes into account the complex practical, political, and economic challenges of the transition towards a carbon-free power system. Thus, we propose to think of the future European market design as a Power Market Pentagon.

A modelling breakthrough for market design analysis to test massive intermittent generation integration in markets results of selected OPTIMATE studies

DEFF Research Database (Denmark)

Beaude, Francois; Atayi, A.; Bourmaud, J.-Y.

2013-01-01

The OPTIMATE1 platform focuses on electricity system and market designs modelling in order to assess current and innovative designs in Europe. The current paper describes the results of the first validation studies' conducted with the tool. These studies deal with day-ahead market rules, load...... flexibility, cross-border management and intermittent renewable support schemes with a view to better integrating large amounts of renewable energy in Europe. Market and system designs were assessed based on economic efficiency, security of supply2 and environmental impact3 indicators. These results give...

A sustainable energy market design for Germany. A capacity market with decentralized demand structure; Der Leistungsmarkt mit dezentraler Nachfrage. Ein zukunftsfaehiges Energiemarktdesign fuer Deutschland

Energy Technology Data Exchange (ETDEWEB)

Ecke, Julius; Herrmann, Nicolai [enervis energy advisors GmbH, Berlin (Germany)

2013-09-01

The German energy policy debate is currently focusing on different design options for a capacity mechanism. With VKU and BDEW, two leading associations in which almost all German energy market actors are represented, have positioned themselves in favor of a decidedly market-based capacity mechanism. The position of the VKU is based on the study ''A sustainable energy market design for Germany'', which was presented in March 2013. The following article describes the state of the energy market design debate in Germany and summarizes the proposed market design resulting from the VKU study. (orig.)

Analysis of the impact of imbalance settlement design on market behaviour in electricity balancing markets

NARCIS (Netherlands)

Van der Veen, R.A.C.; Abbasy, A.; Hakvoort, R.A.

2010-01-01

The imbalance settlement design is the part of an electricity balancing market design that stimulates so-called Balance Responsible Parties (BRPs) to balance their electricity production and consumption portfolio and to stick to their energy schedules by penalizing any deviations from these

Principia designae pre-design, design, and post-design : social motive for the highly advanced technological society

CERN Document Server

2015-01-01

This book presents a broad design purview within the framework of “pre-design, design, and post-design” by focusing on the “motive of design,” which implies an underlying reason for the design of a product. The chapters are comprised of papers based on discussions at the “Design Research Leading Workshop” held in Nara, Japan, in 2013. This book encourages readers to enhance and expand their thinking within a widened design perspective.

Japanese contributions to IAEA INTOR workshop, phase two A, part 2, chapter IV: RF heating and current drive

International Nuclear Information System (INIS)

Sugihara, Masayoshi; Kimura, Haruyuki; Okazaki, Takashi

1985-07-01

This report corresponds to Chapter IV of Japanese contribution report to IAEA INTOR Workshop, phase Two A, Part 2. Data base assessments of plasma heating and launcher system design for Ion Cyclotron Range of Frequency (ICRF) wave, for Lower Hybrid Range of Frequency (LHRF) wave, and for Electron Cyclotron Range of Frequency (ECRF) wave are made. Assessments of current drive by LHRF, and of start-up assist and profile control by ECRF are also made. R and D programmes both physics and technology for each of the waves are specified. Applications of these waves to INTOR are examined. (author)

Market Designs for High Levels of Variable Generation: Preprint

Energy Technology Data Exchange (ETDEWEB)

Milligan, M.; Holttinen, H.; Kiviluoma, J.; Orths, A.; Lynch, M.; Soder, L.

2014-10-01

Variable renewable generation is increasing in penetration in modern power systems, leading to higher variability in the supply and price of electricity as well as lower average spot prices. This raises new challenges, particularly in ensuring sufficient capacity and flexibility from conventional technologies. Because the fixed costs and lifetimes of electricity generation investments are significant, designing markets and regulations that ensure the efficient integration of renewable generation is a significant challenge. This papers reviews the state of play of market designs for high levels of variable generation in the United States and Europe and considers new developments in both regions.

Safety and efficacy of gadoteric acid in pediatric magnetic resonance imaging: overview of clinical trials and post-marketing studies

Energy Technology Data Exchange (ETDEWEB)

Balassy, Csilla [Medical University of Vienna, Vienna General Hospital, Department of Radiology, Division of General and Pediatric Radiology, Vienna (Austria); Roberts, Donna [Medical University of South Carolina, Department of Radiology, Charleston, SC (United States); Miller, Stephen F. [LeBonheur Children' s Hospital, Department of Radiology, Memphis, TN (United States)

2015-11-15

Gadoteric acid is a paramagnetic gadolinium macrocyclic contrast agent approved for use in MRI of cerebral and spinal lesions and for body imaging. To investigate the safety and efficacy of gadoteric acid in children by extensively reviewing clinical and post-marketing observational studies. Data were collected from 3,810 children (ages 3 days to 17 years) investigated in seven clinical trials of central nervous system (CNS) imaging (n = 141) and six post-marketing observational studies of CNS, musculoskeletal and whole-body MR imaging (n = 3,669). Of these, 3,569 children were 2-17 years of age and 241 were younger than 2 years. Gadoteric acid was generally administered at a dose of 0.1 mmol/kg. We evaluated image quality, lesion detection and border delineation, and the safety of gadoteric acid. We also reviewed post-marketing pharmacovigilance experience. Consistent with findings in adults, gadoteric acid was effective in children for improving image quality compared with T1-W unenhanced sequences, providing diagnostic improvement, and often influencing the therapeutic approach, resulting in treatment modifications. In studies assessing neurological tumors, gadoteric acid improved border delineation, internal morphology and contrast enhancement compared to unenhanced MR imaging. Gadoteric acid has a well-established safety profile. Among all studies, a total of 10 children experienced 20 adverse events, 7 of which were thought to be related to gadoteric acid. No serious adverse events were reported in any study. Post-marketing pharmacovigilance experience did not find any specific safety concern. Gadoteric acid was associated with improved lesion detection and delineation and is an effective and well-tolerated contrast agent for use in children. (orig.)

Safety and efficacy of gadoteric acid in pediatric magnetic resonance imaging: overview of clinical trials and post-marketing studies.

Science.gov (United States)

Balassy, Csilla; Roberts, Donna; Miller, Stephen F

2015-11-01

Gadoteric acid is a paramagnetic gadolinium macrocyclic contrast agent approved for use in MRI of cerebral and spinal lesions and for body imaging. To investigate the safety and efficacy of gadoteric acid in children by extensively reviewing clinical and post-marketing observational studies. Data were collected from 3,810 children (ages 3 days to 17 years) investigated in seven clinical trials of central nervous system (CNS) imaging (n = 141) and six post-marketing observational studies of CNS, musculoskeletal and whole-body MR imaging (n = 3,669). Of these, 3,569 children were 2-17 years of age and 241 were younger than 2 years. Gadoteric acid was generally administered at a dose of 0.1 mmol/kg. We evaluated image quality, lesion detection and border delineation, and the safety of gadoteric acid. We also reviewed post-marketing pharmacovigilance experience. Consistent with findings in adults, gadoteric acid was effective in children for improving image quality compared with T1-W unenhanced sequences, providing diagnostic improvement, and often influencing the therapeutic approach, resulting in treatment modifications. In studies assessing neurological tumors, gadoteric acid improved border delineation, internal morphology and contrast enhancement compared to unenhanced MR imaging. Gadoteric acid has a well-established safety profile. Among all studies, a total of 10 children experienced 20 adverse events, 7 of which were thought to be related to gadoteric acid. No serious adverse events were reported in any study. Post-marketing pharmacovigilance experience did not find any specific safety concern. Gadoteric acid was associated with improved lesion detection and delineation and is an effective and well-tolerated contrast agent for use in children.

Safety and efficacy of gadoteric acid in pediatric magnetic resonance imaging: overview of clinical trials and post-marketing studies

International Nuclear Information System (INIS)

Balassy, Csilla; Roberts, Donna; Miller, Stephen F.

2015-01-01

Gadoteric acid is a paramagnetic gadolinium macrocyclic contrast agent approved for use in MRI of cerebral and spinal lesions and for body imaging. To investigate the safety and efficacy of gadoteric acid in children by extensively reviewing clinical and post-marketing observational studies. Data were collected from 3,810 children (ages 3 days to 17 years) investigated in seven clinical trials of central nervous system (CNS) imaging (n = 141) and six post-marketing observational studies of CNS, musculoskeletal and whole-body MR imaging (n = 3,669). Of these, 3,569 children were 2-17 years of age and 241 were younger than 2 years. Gadoteric acid was generally administered at a dose of 0.1 mmol/kg. We evaluated image quality, lesion detection and border delineation, and the safety of gadoteric acid. We also reviewed post-marketing pharmacovigilance experience. Consistent with findings in adults, gadoteric acid was effective in children for improving image quality compared with T1-W unenhanced sequences, providing diagnostic improvement, and often influencing the therapeutic approach, resulting in treatment modifications. In studies assessing neurological tumors, gadoteric acid improved border delineation, internal morphology and contrast enhancement compared to unenhanced MR imaging. Gadoteric acid has a well-established safety profile. Among all studies, a total of 10 children experienced 20 adverse events, 7 of which were thought to be related to gadoteric acid. No serious adverse events were reported in any study. Post-marketing pharmacovigilance experience did not find any specific safety concern. Gadoteric acid was associated with improved lesion detection and delineation and is an effective and well-tolerated contrast agent for use in children. (orig.)

Evolution of Wholesale Electricity Market Design with Increasing Levels of Renewable Generation

Energy Technology Data Exchange (ETDEWEB)

Ela, E.; Milligan, M.; Bloom, A.; Botterud, A.; Townsend, A.; Levin, T.

2014-09-01

Variable generation such as wind and photovoltaic solar power has increased substantially in recent years. Variable generation has unique characteristics compared to the traditional technologies that supply energy in the wholesale electricity markets. These characteristics create unique challenges in planning and operating the power system, and they can also influence the performance and outcomes from electricity markets. This report focuses on two particular issues related to market design: revenue sufficiency for long-term reliability and incentivizing flexibility in short-term operations. The report provides an overview of current design and some designs that have been proposed by industry or researchers.

Designing competitive electricity markets

International Nuclear Information System (INIS)

Chao, H.P.; Huntington, H.

1998-01-01

This volume of papers, originally presented at Stanford in March 1997 in a conference sponsored by the Electric Power Research Institute, examines several questions about the restructuring and deregulation of electricity markets. Its stated goal is to present guiding principles for evaluating proposals to restructure the US electric power industry. While a collection of essays is perhaps not the best place to lay out guiding principles, the volume does contain a great deal of learning about restructuring. The first essay is a reprint of Paul Joskow's excellent article in the ''Journal of Economic Perspectives''. An essay by William Hogan on the debate between zonal and locational pricing is next. Paul Kleindorfer lists the various governance schemes which other countries that have restructured have used to govern system operation, access to the market for power, and transmission ownership and pricing. One difficulty with the book, as well as the debate in the US, is that it fails to draw adequately upon the international experience. Shmuel Oren lays out the potential areas over which an ISO could have authority. The chapter by Stephen Rassenti and Vernon Smith that bilateral trading should never be allowed, implying that a mandatory pool should be established. A reduction in regulation may increase the incentives for technological innovation. Martin Baughman suggests a number of ways by which costs of transmitting and storing electricity may be reduced. Robert Wilson returns to the volume with a chapter on institutional design. To end the volume, Hung-Po Chao and Stephen Peck present an extension of their earlier work in the ''Journal of Regulatory Economics'' showing how markets for transmission rights would work in a transmission grid of three points

A Post-Modern Portfolio Management Approach on CEE Markets

Directory of Open Access Journals (Sweden)

Marcela-Daniela Todoni

2015-01-01

Full Text Available In this paper we apply two methods based on the Post-Modern Portfolio Management approach to study the risk-adjusted return of 5 major indices from emerging markets in Central and Eastern Europe during the period 2008-2013 on daily data. First, we involve the Sortino ratio. Secondly we propose an alternative method to the Sortino ratio for calculating the risk-adjusted return using a “multipliers method” to determine a global measure of risk. The Sortino ratio is used to score a portfolio's risk-adjusted returns relative to an investment target using downside risk and it measures the risk-adjusted return of an investment asset, portfolio or strategy. Our proposed alternative method is using the same logic and frame structure as Sortino ratio. However instead of downside risk we use the global risk calculated using multipliers. This is due to the fact that Sortino ratio does not distinguish between sub-cases possible – unrealized return area and loss area (negative return. Because of these we believe that it would be necessary a new method which to refine the results and take and into account the three areas. Our dataset includes 5 emerging markets: Romania (BET, Hungary (BUX, Czech Republic (PX, Bulgaria (SOFIX and Poland (WIG. For each of them we estimate the Sortino ratio of length windows 7, 14, 42 and 10, 21, 60. We used two variants for each target return, namely 2% and 5%. We consider Germany as a benchmark. After estimating the Sortino ratio and global risk calculated using “multipliers method”, we conducted a parallel analysis between Sortino ratio and the proposed alternative method. We split the analysis time span in two sub-periods, 2008-2010 and 2011-2013. As known, the higher the Sortino ratio, the better the risk-adjusted performance. The risk-adjusted return is influenced by the used target return and the used window. Analyzed data reveals that in case of Sortino ratio, Hungary has the best results and on the other side

Alternate design concept for the SSC dipole magnet cryogenic support post

International Nuclear Information System (INIS)

Lipski, A.; Nicol, T.H.; Richardson, R.

1991-03-01

New materials and developments in the field of advanced composites have created the opportunity to take a fresh look into the design of the cryogenic supports for SSC collider dipole cryostats. Although the present reentrant post design meets the structural and thermal requirements, its assembly requires precision and proficiency. The objective of the proposed alternate concept is to reduce the overall cost of the support post by means of simplifying and optimizing its component design and assembly process. The present shrink fitted tube assembly may potentially be replaced by injection molded parts. New resin systems with lower thermal conductivity and high strength properties enable the utilization of automated production techniques such as injection molding and filament winding. This paper will provide analysis and design information for the alternate support post concept and compare its test performance and cost to the present support post. 3 refs., 12 figs., 4 tabs

Post-market drug evaluation research training capacity in Canada: an environmental scan of Canadian educational institutions.

Science.gov (United States)

Wiens, Matthew O; Soon, Judith A; MacLeod, Stuart M; Sharma, Sunaina; Patel, Anik

2014-01-01

Ongoing efforts by Health Canada intended to modernize the legislation and regulation of pharmaceuticals will help improve the safety and effectiveness of drug products. It will be imperative to ensure that comprehensive and specialized training sites are available to train researchers to support the regulation of therapeutic products. The objective of this educational institution inventory was to conduct an environmental scan of educational institutions in Canada able to train students in areas of post-market drug evaluation research. A systematic web-based environmental scan of Canadian institutions was conducted. The website of each university was examined for potential academic programs. Six core programmatic areas were determined a priori as necessary to train competent post-market drug evaluation researchers. These included biostatistics, epidemiology, pharmacoepidemiology, health economics or pharmacoeconomics, pharmacogenetics or pharmacogenomics and patient safety/pharmacovigilance. Twenty-three academic institutions were identified that had the potential to train students in post-market drug evaluation research. Overall, 23 institutions taught courses in epidemiology, 22 in biostatistics, 17 in health economics/pharmacoeconomics, 5 in pharmacoepidemiology, 5 in pharmacogenetics/pharmacogenomics, and 3 in patient safety/pharmacovigilance. Of the 23 institutions, only the University of Ottawa offered six core courses. Two institutions offered five, seven offered four and the remaining 14 offered three or fewer. It is clear that some institutions may offer programs not entirely reflected in the nomenclature used for this review. As Heath Canada moves towards a more progressive licensing framework, augmented training to increase research capacity and expertise in drug safety and effectiveness is timely and necessary.

The Importance of Course Design on Classroom Performance of Marketing Students

Science.gov (United States)

Black, Gregory S.; Daughtrey, Clayton L.; Lewis, Jeffrey S.

2014-01-01

The main objective of this study was to investigate the impact of course design on marketing student outcomes by examining data gathered over several semesters from 563 undergraduate students enrolled in marketing classes at a major university. During this period of time, respondents were enrolled in one of four marketing courses, each of which…

Economics and business administration post-graduates in transition from university to work: Labor market success factors

NARCIS (Netherlands)

Bijker, Monique; Van der Klink, Marcel; Boshuizen, Els

2012-01-01

Bijker, M. M., Van der Klink, M. R., & Boshuizen, H. P. A. (2012, 13-17 April). Economics and business administration post-graduates in transition from university to work: Labor market success factors. Paper presented at the Annual Meeting of the American Education Research Association (AERA),

Designing Online Marketplace To Resolve Marketing Problem For Small and Medium Enterprises (SMEs)

OpenAIRE

Aditya Hermawan; Aniek Murniati

2017-01-01

The study aims to design an online marketplace to provide solutions to problems faced by Small and Medium Enterprises (SMEs), the difficulty to market their products online. One of the problems faced by SMEs is difficult to market their products online. One of the solutions that we provide is by designing an online marketplace to solve marketing problems effectively. We found that SMEs have attempted to market their products through social media such as facebook, twitter and others. In additi...

Design element analysis on juice market Case study: Prigat

Directory of Open Access Journals (Sweden)

Nicoleta Andreea NEACŞU

2015-06-01

Full Text Available : If at the beginning package was considered simply a package that contained a product, now due to the development and modernization of the trade, it is a very valuable component of the marketing policy, being a carrier of messages to the consumer. Classic design elements that are included in any packaging refer to shape, color and graphics. The Romanian Juices Market was marked by originality and innovation in terms of packaging design elements. Thus, from 1998 until now the following have appeared: the first wide mouth square bottle, the first sport opening head PET bottle for Prigat Active, the first opening gable top box produced in our country.

The role of graphic design in marketing communications

OpenAIRE

Praznik, Daša

2014-01-01

Well designed visual image is the first step of advertising that has an impact on our business partners and consumers. According to Slovenian proverb that "clothes make the man" we could say the same for graphic design and marketing. Well executed graphic design and visual communications enable the communication of our product with a customer. This could be also a communication with artistic approach and a special connection. In order to obtain good results, advertisers use techniques to get...

RIP Input Tables From WAPDEG for LA Design Selection: Continuous Post-Closure Ventilation Design- Open Loop

International Nuclear Information System (INIS)

K.G. Mon; P.K. Mast; R. Howard; J.H. Lee

1999-01-01

The purpose of this calculation is to document (1) the Waste Package Degradation (WAPDEG) version 3.09 (CRWMS M and O 1998b). Software Routine Report for WAPDEG (Version 3.09) simulations used to analyze waste package degradation and failure under the repository exposure conditions characterized by the open loop option of the post-closure ventilation design and, (2) post-processing of these results into tables of waste package degradation time histories suitable for use as input into the Integrated Probabilistic Simulator for Environmental Systems version 5.19.0 1 (RIP) computer program (Golder Associates 1998). Specifically, the WAPDEG simulations discussed in this calculation correspond to waste package emplacement conditions (repository environment and design) defined in the Total System Performance Assessment-Viability Assessment (TSPA-VA), with the exception that the open loop option of the post-closure ventilation License Application Design Selection (LADS) Design Alternative (Design Alternative 3b) was analyzed. The open loop post-closure ventilation design alternative, under which airways to the surface remain open after repository closure, could result in substantial cooling and drying of the potential repository. In open loop post-closure ventilation, expanded air heated by waste decay would move up an exhaust shaft, pulling denser, cooler air into the repository through intake shafts. The exchange of air with the atmosphere could remove more heat and moisture. As a result of the enhanced ventilation relative to the TSPA-VA base-case design, different temperature and relative humidity time histories at the waste package surface are calculated (input to the WAPDEG simulations), and consequently different waste package failure histories (as calculated by WAPDEG) result

Marketing Communications in the Post-Advertising Era.

Science.gov (United States)

Dilenschneider, Robert L.

1991-01-01

Challenges four commonly held myths about advertising and marketing effectiveness. Establishes the framework for a more comprehensive program of marketing communication involving traditional public relations, advertising, sales promotion, special events, along with new uses for public affairs work in marketing. (MG)

Allocation Problems and Market Design

DEFF Research Database (Denmark)

Smilgins, Aleksandrs

The thesis contains six independent papers with a common theme: Allocation problems and market design. The first paper is concerned with fair allocation of risk capital where independent autonomous subunits have risky activities and together constitute the entity's total risk, whose associated risk...... at a certain point in time involves countries that have excess demand and countries that have surplus of green energy. The problem addressed here is how the gains from trade ought to influence the way that members of the grid share common costs. The fifth paper extends the classical two-sided one...

What marketing strategy for destinations with a negative image?

OpenAIRE

Seraphin, Hugues; Gowreesunkar, Vanessa; Hugues Seraphin

2017-01-01

Purpose\\ud This concluding article filters out meaningful marketing strategies that aim at re-positioning and re-establishing struggling tourism destinations with negative image. Drawing from a collection of case studies around the world, the article provides evidences from post-colonial, post-conflict and post-disaster destinations to finally anchor the overall conclusion of the theme issue.\\ud \\ud Design\\ud The article summarizes key issues faced by destinations plagued with a negative imag...

Design and market considerations for axial flux superconducting electric machine design

Science.gov (United States)

Ainslie, M. D.; George, A.; Shaw, R.; Dawson, L.; Winfield, A.; Steketee, M.; Stockley, S.

2014-05-01

In this paper, the authors investigate a number of design and market considerations for an axial flux superconducting electric machine design that uses high temperature superconductors. The axial flux machine design is assumed to utilise high temperature superconductors in both wire (stator winding) and bulk (rotor field) forms, to operate over a temperature range of 65-77 K, and to have a power output in the range from 10s of kW up to 1 MW (typical for axial flux machines), with approximately 2-3 T as the peak trapped field in the bulk superconductors. The authors firstly investigate the applicability of this type of machine as a generator in small- and medium-sized wind turbines, including the current and forecasted market and pricing for conventional turbines. Next, a study is also carried out on the machine's applicability as an in-wheel hub motor for electric vehicles. Some recommendations for future applications are made based on the outcome of these two studies. Finally, the cost of YBCO-based superconducting (2G HTS) wire is analysed with respect to competing wire technologies and compared with current conventional material costs and current wire costs for both 1G and 2G HTS are still too great to be economically feasible for such superconducting devices.

Policy design and performance of emissions trading markets: an adaptive agent-based analysis.

Science.gov (United States)

Bing, Zhang; Qinqin, Yu; Jun, Bi

2010-08-01

Emissions trading is considered to be a cost-effective environmental economic instrument for pollution control. However, the pilot emissions trading programs in China have failed to bring remarkable success in the campaign for pollution control. The policy design of an emissions trading program is found to have a decisive impact on its performance. In this study, an artificial market for sulfur dioxide (SO2) emissions trading applying the agent-based model was constructed. The performance of the Jiangsu SO2 emissions trading market under different policy design scenario was also examined. Results show that the market efficiency of emissions trading is significantly affected by policy design and existing policies. China's coal-electricity price system is the principal factor influencing the performance of the SO2 emissions trading market. Transaction costs would also reduce market efficiency. In addition, current-level emissions discharge fee/tax and banking mechanisms do not distinctly affect policy performance. Thus, applying emissions trading in emission control in China should consider policy design and interaction with other existing policies.

European electricity markets - policy deficiencies, design deficiencies, and opportunities for policy-makers

International Nuclear Information System (INIS)

Bettzuge, Marc Oliver

2013-11-01

Paraphrasing a well-known dictum, one can say that 'design follows policies'. Therefore, before discussing questions of market design, one has to clarify the policies which the desired market design is supposed to implement. Hence, this paper starts by briefly reviewing the status of current policies for the electricity sector. Specifically, it will discuss political objectives, the choice of the basic regulatory paradigm, and the issue of subsidiarity between the EU and the member states

Impact of Insurance Market on Economic Growth in Post-Transition Countries

Directory of Open Access Journals (Sweden)

Phutkaradze Jaba

2014-12-01

Full Text Available The purpose of this work is to identify whether the development of an insurance market is linked to economic growth in former transition countries. A multiple regression analysis is employed to estimate the insurance-growth relationship, using a cross-country panel dataset analysis tracking annual total insurance penetration in 10 countries over the 2000-2012 period, and applying a fixed effect model to test the hypothesis that this linkage is demonstrably positive. The results show a negative and statistically non-significant correlation between insurance and GDP growth, suggesting a lack of evidence that insurance promotes economic growth in post-transition economies.

The Internationalization and Market Competition of Tsai Yueh-Hsun’s Post-Confucian TV Drama and Films in East Asia

Directory of Open Access Journals (Sweden)

Jocelyn Yi-Hsuan Lai

2018-04-01

Full Text Available This essay investigates the East Asia-oriented TV and film productions of Taiwanese producer-director Tsai Yueh-hsun. His productions have made wide use of the transnational bankability of Taiwanese TV stars. Set in nationally non-specific urban societies, they are categorized as post-Confucian TV dramas, adopting liberal Western values and presenting problems in the authoritative patriarchal culture of the modern yet Confucian East Asia. They have competed in this market with neo-Confucian Korean and mainland Chinese TV dramas that follow Confucian patriarchal values. His productions in the 2000s entered many East Asian markets, including Southeast Asian countries, Japan, and mainland China, with the latter airing censored versions. In the 2010s, his productions have prioritized the rapidly increasing mainland Chinese market among all East Asian markets and adopted Taiwanese-mainland Chinese cooperation. The productions maintain the post-Confucian style of presentation, but remove the political viewpoint commonly perceived in Taiwan. Confronted with Taiwanese skepticism toward the Taiwanese-mainland Chinese cooperation, Tsai argues that this strategy will contribute to the development of Taiwan’s film and TV industry. The presentation of Taiwan’s modern places in the productions will help promote its tourism.

Designing an Energy Drink: High School Students Learn Design and Marketing Skills in This Activity

Science.gov (United States)

Martin, Doug

2008-01-01

A decade ago, energy drinks were almost nonexistent in the United States, but in the past five years they've become wildly popular. In fact, the $3.4 billion energy-drink market is expected to double this year alone, and the younger generation is the market targeted by manufacturers. This article presents an energy-drink designing activity. This…

Design Extension in Post Fukushima Scenario

International Nuclear Information System (INIS)

Kumar, Prabhat

2013-01-01

Post Fukushima Flooding Review and Design Extension: • Increased tsunami height; • Increased tsunami wall;• Increased size of storm water drains; • Non return gates in storm water drains; • Wall around fore bay and sea water pump house; • Sealing of NIB penetrations for a higher tsunami; • Alternative approach road; • NICB elevation; • Perpendicular to coast line

Pediatric post-marketing safety systems in North America: assessment of the current status.

Science.gov (United States)

McMahon, Ann W; Wharton, Gerold T; Bonnel, Renan; DeCelle, Mary; Swank, Kimberley; Testoni, Daniela; Cope, Judith U; Smith, Phillip Brian; Wu, Eileen; Murphy, Mary Dianne

2015-08-01

It is critical to have pediatric post-marketing safety systems that contain enough clinical and epidemiological detail to draw regulatory, public health, and clinical conclusions. The pediatric safety surveillance workshop (PSSW), coordinated by the Food and Drug Administration (FDA), identified these pediatric systems as of 2010. This manuscript aims to update the information from the PSSW and look critically at the systems currently in use. We reviewed North American pediatric post-marketing safety systems such as databases, networks, and research consortiums found in peer-reviewed journals and other online sources. We detail clinical examples from three systems that FDA used to assess pediatric medical product safety. Of the 59 systems reviewed for pediatric content, only nine were pediatric-focused and met the inclusion criteria. Brief descriptions are provided for these nine. The strengths and weaknesses of three systems (two of the nine pediatric-focused and one including both children and adults) are illustrated with clinical examples. Systems reviewed in this manuscript have strengths such as clinical detail, a large enough sample size to capture rare adverse events, and/or a patient denominator internal to the database. Few systems include all of these attributes. Pediatric drug safety would be better informed by utilizing multiple systems to take advantage of their individual characteristics. Copyright © 2015 John Wiley & Sons, Ltd.

Global or local construction materials for post-disaster reconstruction? Sustainability assessment of 20 post-disaster shelter designs

OpenAIRE

Zea Escamilla, E.; Habert, G.

2015-01-01

This data article presents the life cycle inventories of 20 transitional shelter solutions. The data was gathered from the reports 8 shelter designs [1]; 10 post-disaster shelter designs [2]; the environmental impact of brick production outside of Europe [3]; and the optimization of bamboo-based post-disaster housing units for tropical and subtropical regions using LCA methodologies [4]. These reports include bill of quantities, plans, performance analysis, and lifespan of the studied shelter...

Integration of a clinical trial database with a PACS

International Nuclear Information System (INIS)

Van Herk, M

2014-01-01

Many clinical trials use Electronic Case Report Forms (ECRF), e.g., from OpenClinica. Trial data is augmented if DICOM scans, dose cubes, etc. from the Picture Archiving and Communication System (PACS) are included for data mining. Unfortunately, there is as yet no structured way to collect DICOM objects in trial databases. In this paper, we obtain a tight integration of ECRF and PACS using open source software. Methods: DICOM identifiers for selected images/series/studies are stored in associated ECRF events (e.g., baseline) as follows: 1) JavaScript added to OpenClinica communicates using HTML with a gateway server inside the hospitals firewall; 2) On this gateway, an open source DICOM server runs scripts to query and select the data, returning anonymized identifiers; 3) The scripts then collects, anonymizes, zips and transmits selected data to a central trial server; 4) Here data is stored in a DICOM archive which allows authorized ECRF users to view and download the anonymous images associated with each event. Results: All integration scripts are open source. The PACS administrator configures the anonymization script and decides to use the gateway in passive (receiving) mode or in an active mode going out to the PACS to gather data. Our ECRF centric approach supports automatic data mining by iterating over the cases in the ECRF database, providing the identifiers to load images and the clinical data to correlate with image analysis results. Conclusions: Using open source software and web technology, a tight integration has been achieved between PACS and ECRF.

Construction and analysis of a human hepatotoxicity database suitable for QSAR modeling using post-market safety data

International Nuclear Information System (INIS)

Zhu, Xiao; Kruhlak, Naomi L.

2014-01-01

Graphical abstract: - Abstract: Drug-induced liver injury (DILI) is one of the most common drug-induced adverse events (AEs) leading to life-threatening conditions such as acute liver failure. It has also been recognized as the single most common cause of safety-related post-market withdrawals or warnings. Efforts to develop new predictive methods to assess the likelihood of a drug being a hepatotoxicant have been challenging due to the complexity and idiosyncrasy of clinical manifestations of DILI. The FDA adverse event reporting system (AERS) contains post-market data that depict the morbidity of AEs. Here, we developed a scalable approach to construct a hepatotoxicity database using post-market data for the purpose of quantitative structure–activity relationship (QSAR) modeling. A set of 2029 unique and modelable drug entities with 13,555 drug-AE combinations was extracted from the AERS database using 37 hepatotoxicity-related query preferred terms (PTs). In order to determine the optimal classification scheme to partition positive from negative drugs, a manually-curated DILI calibration set composed of 105 negatives and 177 positives was developed based on the published literature. The final classification scheme combines hepatotoxicity-related PT data with supporting information that optimize the predictive performance across the calibration set. Data for other toxicological endpoints related to liver injury such as liver enzyme abnormalities, cholestasis, and bile duct disorders, were also extracted and classified. Collectively, these datasets can be used to generate a battery of QSAR models that assess a drug's potential to cause DILI

Uranium and nuclear market, the horizon post-Fukushima

International Nuclear Information System (INIS)

Lelièvre, F.

2014-01-01

Post-Fukushima, most countries have confirmed the importance of nuclear in their energy mix. We are seeing a level of new reactor construction unparalleled in decades with 61 nuclear power plants under construction and 5 plants under completion around the world. Global nuclear capacity is expected to increase by 50% over the next two decades. And more reactors mean more demand for uranium. However, uranium industry is currently grappling with near-term challenges, particularly in the form of depressed uranium prices. Recently several uranium producers announced production delays or cancellations in response to low prices, including major suppliers. As the current price levels, including long-term prices, are not sufficient to stimulate new production, future supplies are in question due to the long-lead nature of uranium mine development. Despite the near- to medium-term issues of our industry, the fundamentals of the uranium market remain strong over the long term - and these are the drivers of the Areva’s mining growth strategy over the coming years. (author)

78 FR 32988 - Core Principles and Other Requirements for Designated Contract Markets; Correction

Science.gov (United States)

2013-06-03

... COMMODITY FUTURES TRADING COMMISSION 17 CFR Part 38 RIN 3038-AD09 Core Principles and Other... regarding Core Principles and Other Requirements for Designated Contract Markets by inserting a missing... regarding Core Principles and Other Requirements for Designated Contract Markets (77 FR 36612, June 19, 2012...

[Nationwide Survey on Informed Consent and Ethical Review at Hospitals Conducting Post-marketing Studies Sponsored by Pharmaceutical Companies].

Science.gov (United States)

Urushihara, Hisashi; Murakami, Yuka; Matsui, Kenji; Tashiro, Shimon

2018-01-01

 Under the Japanese drug regulatory system, post-marketing studies (PMS) must be in compliance with Good Post-marketing Study Practice (GPSP). The GPSP Ordinance lacks standards for the ethical conduct of PMSs; although only post-marketing clinical trials are subject to Good Clinical Practice. We conducted a web-based questionnaire survey on the ethical conduct of PMSs in collaboration with the Japanese Society of Hospital Pharmacists and pharmacists belonging to the Society. 1819 hospitals around Japan answered the questionnaire, of which 503 hospitals had conducted company-sponsored PMSs in 2015. 40.2% of the hospitals had obtained informed consent from participating patients in at least one PMS conducted in 2015, the majority of which was in written form. The first and second most frequent reasons for seeking informed consent in PMSs were to meet protocol requirements, followed by the requirement to meet institutional standard operational procedures and the request of the ethical review board of the hospital. Ethical review of PMSs was conducted in 251 hospitals. Despite a lack of standards for informed consent and ethical review in PMSs, a considerable number of study sites employed informed consent and ethical review for PMSs. While company policies and protocols are likely to be major determinants of the ethical conduct of PMSs, the governmental regulatory agency should also play a significant role in implementing a standardized ethical code for the conduct of PMSs.

Global or local construction materials for post-disaster reconstruction? Sustainability assessment of 20 post-disaster shelter designs.

Science.gov (United States)

Zea Escamilla, E; Habert, G

2015-09-01

This data article presents the life cycle inventories of 20 transitional shelter solutions. The data was gathered from the reports 8 shelter designs [1]; 10 post-disaster shelter designs [2]; the environmental impact of brick production outside of Europe [3]; and the optimization of bamboo-based post-disaster housing units for tropical and subtropical regions using LCA methodologies [4]. These reports include bill of quantities, plans, performance analysis, and lifespan of the studied shelters. The data from these reports was used to develop the Life Cycle Inventories (LCI). All the amounts were converted from their original units (length, volume and amount) into mass (kg) units and the transport distance into ton×km. These LCIs represent the production phases of each shelter and the transportation distances for the construction materials. Two types of distances were included, local (road) and international (freight ship), which were estimated based on the area of the country of study. Furthermore, the digital visualization of the shelters is presented for each of the 20 designs. Moreover, this data article presents a summary of the results for the categories Environment, Cost and Risk and the contribution to the environmental impact from the different building components of each shelter. These results are related to the article "Global or local construction materials for post-disaster reconstruction? Sustainability assessment of 20 post-disaster shelter designs"[5].

Volume Shocks around Announcements in the Chinese Stock Market: An Ex-Post Earnings-Information-Based Study of Speculative Behavior

Directory of Open Access Journals (Sweden)

Xiangdong Chen

2017-09-01

Full Text Available The Second Board Market is typical stock market for high tech companies in China. This paper discusses the relationship between trading volume and price changes in the case of high-tech listed companies in the Chinese Second-Board Stock Market. By using the basic concepts proposed by Kim and Verrecchia, and Kandel and Pearson, and contrasting them with ex-post information from earnings releases, the paper provides findings on the speculative behavior of informed traders with a volume shock premium. The paper suggests that these methods may be further applied to investigating investors’ behavior in speculation, especially for the high-tech-company-based Second-Board Stock Market during announcement periods.

[Comparative study on four kinds of assessment methods of post-marketing safety of Danhong injection].

Science.gov (United States)

Li, Xuelin; Tang, Jinfa; Meng, Fei; Li, Chunxiao; Xie, Yanming

2011-10-01

To study the adverse reaction of Danhong injection with four kinds of methods, central monitoring method, chart review method, literature study method and spontaneous reporting method, and to compare the differences between them, explore an appropriate method to carry out post-marketing safety evaluation of traditional Chinese medicine injection. Set down the adverse reactions' questionnaire of four kinds of methods, central monitoring method, chart review method, literature study method and collect the information on adverse reactions in a certain period. Danhong injection adverse reaction information from Henan Province spontaneous reporting system was collected with spontaneous reporting method. Carry on data summary and descriptive analysis. Study the adverse reaction of Danhong injection with four methods of central monitoring method, chart review method, literature study method and spontaneous reporting method, the rates of adverse events were 0.993%, 0.336%, 0.515%, 0.067%, respectively. Cyanosis, arrhythmia, hypotension, sweating, erythema, hemorrhage dermatitis, rash, irritability, bleeding gums, toothache, tinnitus, asthma, elevated aminotransferases, constipation, pain are new discovered adverse reactions. The central monitoring method is the appropriate method to carry out post-marketing safety evaluation of traditional Chinese medicine injection, which could objectively reflect the real world of clinical usage.

Monopolies, liberalization, energy turnaround. (Dis)continuities in the electricity market design

International Nuclear Information System (INIS)

Grashof, Katherina; Zipp, Alexander; Jachmann, Henning; Wille-Haussmann, Bernhard; Lechtenboehmer, Stefan

2015-01-01

After a long period of stability, the electricity industry is in the past 15 years, in a major state of flux. First, the switching of state-monitored and regulated regional monopolies to liberalized producer and consumer markets. At the moment we are in a similar change from conventional to renewable energy production. Below the main question will be addressed whether the paradigms of the individual phases are compatible, which still have their place and which should be modified. Moreover, it is shown that the current market design of the future cannot be designed on a blank sheet, but existing structures have to be considered. Given the stage of monopolies, the liberalization and the started energy turnaround respectively in terms of their sector structure, dominant generation technologies, the interaction between production and load and characteristic elements of market design and regulation are presented. Subsequently, a preliminary answer is given to the question raised. [de

Systematic review of reporting rates of adverse events following immunization: an international comparison of post-marketing surveillance programs with reference to China.

Science.gov (United States)

Guo, Biao; Page, Andrew; Wang, Huaqing; Taylor, Richard; McIntyre, Peter

2013-01-11

China is the most populous country in the world, with an annual birth cohort of approximately 16 million, requiring an average of 500 million vaccine doses administered annually. In China, over 30 domestic and less than 10 overseas vaccine manufacturers supply over 60 licensed vaccine products, representing a growing vaccine market mainly due to recent additions to the national immunization schedule, but data on post-marketing surveillance for adverse events following immunization (AEFI) are sparse. To compare reporting rates for various categories of AEFI from China with other routine post-marketing surveillance programs internationally. Systematic review of published studies reporting rates of AEFI by vaccine, category of reaction and age from post-marketing surveillance systems in English and Chinese languages. Overall AEFI reporting rates (all vaccines, all ages) in Chinese studies were consistent with those from similar international studies elsewhere, but there was substantial heterogeneity in regional reporting rates in China (range 2.3-37.8/100,000 doses). The highest AEFI reporting rates were for diphtheria-tetanus-pertussis whole-cell (DTwP) and acellular (DTaP) vaccines (range 3.3-181.1/100,000 doses for DTwP; range 3.5-92.6/100,000 doses for DTaP), with higher median rates for DTwP than DTaP, and higher than expected rates for DTaP vaccine. Similar higher rates for DTwP and DTaP containing vaccines, and relatively lower rates for vaccines against hepatitis B virus, poliovirus, and Japanese encephalitis virus were found in China and elsewhere in the world. Overall AEFI reporting rates in China were consistent with similar post-marketing surveillance systems in other countries. Sources of regional heterogeneity in AEFI reporting rates, and their relationships to differing vaccine manufacturers versus differing surveillance practices, require further exploration. Copyright © 2012 Elsevier Ltd. All rights reserved.

CliniProteus: A flexible clinical trials information management system

Science.gov (United States)

Mathura, Venkatarajan S; Rangareddy, Mahendiranath; Gupta, Pankaj; Mullan, Michael

2007-01-01

Clinical trials involve multi-site heterogeneous data generation with complex data input-formats and forms. The data should be captured and queried in an integrated fashion to facilitate further analysis. Electronic case-report forms (eCRF) are gaining popularity since it allows capture of clinical information in a rapid manner. We have designed and developed an XML based flexible clinical trials data management framework in .NET environment that can be used for efficient design and deployment of eCRFs to efficiently collate data and analyze information from multi-site clinical trials. The main components of our system include an XML form designer, a Patient registration eForm, reusable eForms, multiple-visit data capture and consolidated reports. A unique id is used for tracking the trial, site of occurrence, the patient and the year of recruitment. Availability http://www.rfdn.org/bioinfo/CTMS/ctms.html. PMID:21670796

Design Strategy for a Pipelined ADC Employing Digital Post-correction

NARCIS (Netherlands)

Harpe, P.J.A.; Zanikopoulos, A.; Hegt, J.A.; Roermund, van A.H.M.

2004-01-01

This paper describes how the usage of digital post-correction techniques in pipelined analog-to-digital converters (ADC's) can be exploited optimally during the design-phase of the converter. It is known that post-correction algorithms reduce the influence of several cir- cuit impairments on the

Ecological Design : a new post-modern design paradigm, One of holistic philosophy and evalutionary ethic

NARCIS (Netherlands)

Koh, J.

2005-01-01

This papaer will present ecological design as a new paradigm in design, explain its significance, and argue for ecological design as a better paradigmatic alternative to the modern movement led by the Bauhaus, and as a sounder and more socially relevant approach than the post-modernism

Emerging Markets: Theory & Practice / Turkey’s Reforms Post 2001 Crisis

Directory of Open Access Journals (Sweden)

Duygu Uckun

2010-01-01

Full Text Available The global financial downturn of 2001 affected broad swaths of the increasingly interconnected global economy. The global effects of the economic downturn in the U.S. in 2008 showed that decoupling had not occurred to the extent many thought, and showed that indeed emerging market countries, including Turkey, were not immune from economic trouble in America. This paper addresses the question, whether the fiscal, financial, and regulatory reforms in Turkey after the 2001 economic crisis cushion the global financial crisis world is facing toward the end of the decade. In doing so we analyze the policies implemented by Turkey before and after the 2001 global economic crisis and identify the successes as well as failures of those reforms. The results of our research show that despite significant reforms in key economic and regulatory areas in the post-2001 crisis period, vulnerabilities remained; especially concerning the large current account deficit, volatility of exchange rates, increased private sector indebtedness, and persistent unemployment. These vulnerabilities will be visible in the deteriorating liquidity conditions in the global financial markets. We conclude by recommending infrastructure, education and health spending as well as restructuring of the economy to further attract FDI and avoid reliance on speculative foreign capital in order to achieve a more balanced and sustained growth in the long run.

An affective e-commerce design for SMEs product marketing based on kansei engineering

Science.gov (United States)

Habyba, A. N.; Djatna, T.; Anggraeni, E.

2018-04-01

One of the SMEs problems in Indonesia in this information technology era is the inability to control the market. SMEs can use the e-commerce website to improve their competitiveness. It can be used as a marketing tool for SMEs to promote their products and expands the SMEs markets especially for the agroindustry SMEs where located in district area that still rely on local markets to sell their product. Some SMEs e-commerce websites have been developed in Indonesia but can not significantly increased the sales of SMEs product. Furthemore, the design of it is only able to meet the consumer need in function and usability. The development of e-commerce design should pay attention in high affective quality. This is because the affective responses effect the user’s perception of cognitive quality, usability and ease of use of e-commerce. This study is aimed to make e-commerce that can meet the affective needs of users. The result of Kansei words selection and extraction using TF-IDF are four design concepts of e-commerce website. The formulation of new SMEs e-commerce website design is resulted from the integration of four design concepts and four design elements. The “Natural-Formal” concept has the greatest value than other concepts after QTT-1 analysis. This concept can implemented as the new SMEs e-commerce website design.

Vocations: The Link between Post-Compulsory Education and the Labour Market. What the Research Says For... Industry

Science.gov (United States)

Wheelahan, Leesa; Buchanan, John; Yu, Serena

2015-01-01

This summary brings together the relevant key findings for industry from the research program "Vocations: The Link between Post-Compulsory Education and the Labour Market." The program was comprised of three different strands: (1) pathways from VET in Schools, (2) pathways within and between vocational education and training (VET) and…

Results of a customer-based, post-market surveillance survey of the HeRO access device.

Science.gov (United States)

Fusselman, Maureen

2010-08-01

In order to supplement post-market surveillance data on the HeRO vascular access device, a non-scientific customer survey was conducted to obtain quantitative data from dialysis providers caring for patients implanted with the device. Dialysis nurses involved in the care of HeRO patients were contacted in order to obtain post-implant device performance information for 10% of patients implanted with the device at the time of the survey. Thirty-eight dialysis units with a total of 65 HeRO patients participated in the survey. The total duration of HeRO device use was 348.4 months with an average use of 5.4 months. Thirty-eight of the 65 HeRO patients (58.5%) were reported to not have experienced any performance issues. There were 28 device performance incidents reported for the remaining 27 patients included in the survey. Occlusion was the single most commonly reported device-related performance issue with 18 patients (27.7%) experiencing 25 occlusive episodes. The majority of the patients who had an occlusion (66.7%) only experienced one occlusive event. Infections occurred in 4 patients (6.2%) with an overall infection rate of 0.38 per 1,000 patient days. Post-market clinical experience during the first 18 months of commercialization of the HeRO device were in line with expectations based on the results from initial clinical studies with the device. Device occlusion remains the most commonly reported performance issue with the reported rate in this survey less than that which was reported in earlier published studies with the device.

Utilizing national and international registries to enhance pre-market medical device regulatory evaluation.

Science.gov (United States)

Yue, Lilly Q; Campbell, Gregory; Lu, Nelson; Xu, Yunling; Zuckerman, Bram

2016-01-01

Regulatory decisions are made based on the assessment of risk and benefit of medical devices at the time of pre-market approval and subsequently, when post-market risk-benefit balance needs reevaluation. Such assessments depend on scientific evidence obtained from pre-market studies, post-approval studies, post-market surveillance studies, patient perspective information, as well as other real world data such as national and international registries. Such registries provide real world evidence and are playing a more and more important role in enhancing the safety and effectiveness evaluation of medical devices. While these registries provide large quantities of data reflecting real world practice and can potentially reduce the cost of clinical trials, challenges arise concerning (1) data quality adequate for regulatory decision-making, (2) bias introduced at every stage and aspect of study, (3) scientific validity of study designs, and (4) reliability and interpretability of study results. This article will discuss related statistical and regulatory challenges and opportunities with examples encountered in medical device regulatory reviews.

Intercultural design of man-machine systems: Machine design for the Chinese market; Interkulturelles Design fuer Mensch-Maschine-Systeme: Maschinendesign fuer den chinesischen Markt

Energy Technology Data Exchange (ETDEWEB)

Roese, K.; Zuehlke, D.; Liu, L. [Kaiserslautern Univ. (Germany)

2002-07-01

The ongoing globalization trend has imposed great needs on culture-specific machine design. For the expected business success on the foreign market the target user's special requirements should be well addressed. This paper proposes an effective approach to elicit user's culture-specific requirements on different machine design issues, which bases on the analysis of cultural environment and mentality. The approach was practically implemented in one project to elicit the user's requirements on machine design for the Chinese market. The investigation methods are briefly described and some most important culture specific design features for Mainland China are summarized. (orig.)

Urban design for post-earthquake reconstruction: A case study of Wenchuan County, China

NARCIS (Netherlands)

Liu, L.X.; Lin, Y.L.; Wang, S.F.

2014-01-01

Urban design for post-earthquake reconstruction emphasizes strategies, safety, memorials and institutional arrangements. It is closely related to earthquake recovery plans. This article reviews general studies on urban design for post-earthquake reconstruction, before focussing on the case of

Some design lessons from market-based greenhouse gas regulation in the restructured Australian electricity industry

International Nuclear Information System (INIS)

MacGill, Iain; Outhred, Hugh; Nolles, Karel

2006-01-01

There is growing worldwide interest in the use of market-based policy instruments for climate change regulation in the electricity sector. These mechanisms would seem to offer some efficiency and flexibility advantages over more traditional regulatory approaches, while being highly compatible with competitive market-based electricity industries. Australia has been an early and enthusiastic adopter of both electricity industry restructuring and market-based environmental instruments. This paper first outlines some of these recent policy developments. In particular, we describe the objectives, design and outcomes to date of electricity industry restructuring, the Mandatory Renewable Energy Target, the NSW Greenhouse Benchmarks, the Queensland 13% Gas scheme and Government accredited Green Power. From this, we draw some key design lessons for such market-based instruments. These include the perils of abstraction in scheme design, the vital importance of setting appropriate baselines in 'baseline and credit' schemes, the possibility that such measures may interact in ways that reduce their environmental effectiveness, 'market for lemon' risks with tradable instruments that have measurement, verification or 'additionality' difficulties, and the challenges of creating transparent liquid markets for these mechanisms. The mixed performance of these Australian schemes to date illustrates the need for great care in designing such market-based approaches

Some design lessons from market-based greenhouse gas regulation in the restructured Australian electricity industry

Energy Technology Data Exchange (ETDEWEB)

MacGill, Iain [School of Electrical Engineering and Telecommunications, University of New South Wales, Sydney NSW 2052 (Australia)] e-mail: i.macgill@unsw.edu.au; Outhred, Hugh [School of Electrical Engineering and Telecommunications, University of New South Wales, Sydney NSW 2052 (Australia); Nolles, Karel [School of Electrical Engineering and Telecommunications, University of New South Wales, Sydney NSW 2052 (Australia)

2006-01-01

There is growing worldwide interest in the use of market-based policy instruments for climate change regulation in the electricity sector. These mechanisms would seem to offer some efficiency and flexibility advantages over more traditional regulatory approaches, while being highly compatible with competitive market-based electricity industries. Australia has been an early and enthusiastic adopter of both electricity industry restructuring and market-based environmental instruments. This paper first outlines some of these recent policy developments. In particular, we describe the objectives, design and outcomes to date of electricity industry restructuring, the Mandatory Renewable Energy Target, the NSW Greenhouse Benchmarks, the Queensland 13% Gas scheme and Government accredited Green Power. From this, we draw some key design lessons for such market-based instruments. These include the perils of abstraction in scheme design, the vital importance of setting appropriate baselines in 'baseline and credit' schemes, the possibility that such measures may interact in ways that reduce their environmental effectiveness, 'market for lemon' risks with tradable instruments that have measurement, verification or 'additionality' difficulties, and the challenges of creating transparent liquid markets for these mechanisms. The mixed performance of these Australian schemes to date illustrates the need for great care in designing such market-based approaches.

Some design lessons from market-based greenhouse gas regulation in the restructured Australian electricity industry

Energy Technology Data Exchange (ETDEWEB)

Iain MacGill; Hugh Outhred; Karel Nolles [University of New South Wales, Sydney, NSW (Australia). School of Electrical Engineering & Telecommunications

2006-01-01

There is growing worldwide interest in the use of market-based policy instruments for climate change regulation in the electricity sector. These mechanisms would seem to offer some efficiency and flexibility advantages over more traditional regulatory approaches, while being highly compatible with competitive market-based electricity industries. Australia has been an early and enthusiastic adopter of both electricity industry restructuring and market-based environmental instruments. This paper first outlines some of these recent policy developments. It then describes the objectives, design and outcomes to date of electricity industry restructuring, the Mandatory Renewable Energy Target, the NSW Greenhouse Benchmarks, the Queensland 13% Gas scheme and Government accredited Green Power. From this, some key design lessons are drawn for such market-based instruments. These include the perils of abstraction in scheme design, the vital importance of setting appropriate baselines in 'baseline and credit' schemes, the possibility that such measures may interact in ways that reduce their environmental effectiveness, 'market for lemon' risks with tradable instruments that have measurement, verification or 'additionality' difficulties, and the challenges of creating transparent liquid markets for these mechanisms. The mixed performance of these Australian schemes to date illustrates the need for great care in designing such market-based approaches. 36 refs., 2 figs.

POWER for reproductive health: results from a social marketing campaign promoting female and male condoms.

Science.gov (United States)

Bull, Sheana S; Posner, Samuel F; Ortiz, Charlene; Beaty, Brenda; Benton, Kathryn; Lin, Lillian; Pals, Sherri L; Evans, Tom

2008-07-01

To evaluate effects of a 6-month social marketing campaign on awareness of, attitudes toward and use of female as well as male condoms for 15-25 year-old-women. Using a time-space sampling methodology, we conducted a cross-sectional survey of 3407 women at pre-campaign in 12 western U.S. neighborhoods on female and male condom awareness, attitudes, and use. Six of the 12 study neighborhoods were randomly selected to receive the POWER social marketing campaign designed to impact condom knowledge, attitudes, and use. The campaign was followed with another cross-sectional survey of 3,003 women in all 12 study neighborhoods on condom knowledge, attitudes, use and awareness of POWER materials. We compared pre-and post-campaign surveys to determine the efficacy of POWER and conducted post hoc analyses on post-campaign data to determine if exposure to POWER was related to higher levels of positive condom attitudes and norms and condom use. We found no differences between neighborhoods with and without the POWER campaign with regard to our primary outcomes. To diagnose reasons for this null effect, we examined outcomes post hoc examining the influence of POWER exposure. Post hoc analyses show some evidence that exposure to POWER was associated with condom use. In the context of the nested trial, this raises concerns that post test only evaluations are limited. Establishing the efficacy of a social marketing campaign is challenging. This group randomized trial showed a null effect. Social marketing campaigns may need to have more media channels and saturation before they can show behavioral effects. Using a nested design with randomization at the community level and probability sampling introduces rigor not commonly seen in evaluations of social marketing campaigns.

Emerging role of bioinformatics tools and software in evolution of clinical research

Directory of Open Access Journals (Sweden)

Supreet Kaur Gill

2016-01-01

Full Text Available Clinical research is making toiling efforts for promotion and wellbeing of the health status of the people. There is a rapid increase in number and severity of diseases like cancer, hepatitis, HIV etc, resulting in high morbidity and mortality. Clinical research involves drug discovery and development whereas clinical trials are performed to establish safety and efficacy of drugs. Drug discovery is a long process starting with the target identification, validation and lead optimization. This is followed by the preclinical trials, intensive clinical trials and eventually post marketing vigilance for drug safety. Softwares and the bioinformatics tools play a great role not only in the drug discovery but also in drug development. It involves the use of informatics in the development of new knowledge pertaining to health and disease, data management during clinical trials and to use clinical data for secondary research. In addition, new technology likes molecular docking, molecular dynamics simulation, proteomics and quantitative structure activity relationship in clinical research results in faster and easier drug discovery process. During the preclinical trials, the software is used for randomization to remove bias and to plan study design. In clinical trials software like electronic data capture, Remote data capture and electronic case report form (eCRF is used to store the data. eClinical, Oracle clinical are software used for clinical data management and for statistical analysis of the data. After the drug is marketed the safety of a drug could be monitored by drug safety software like Oracle Argus or ARISg. Therefore, softwares are used from the very early stages of drug designing, to drug development, clinical trials and during pharmacovigilance. This review describes different aspects related to application of computers and bioinformatics in drug designing, discovery and development, formulation designing and clinical research.

Global or local construction materials for post-disaster reconstruction? Sustainability assessment of 20 post-disaster shelter designs

Directory of Open Access Journals (Sweden)

E. Zea Escamilla

2015-09-01

Full Text Available This data article presents the life cycle inventories of 20 transitional shelter solutions. The data was gathered from the reports 8 shelter designs [1]; 10 post-disaster shelter designs [2]; the environmental impact of brick production outside of Europe [3]; and the optimization of bamboo-based post-disaster housing units for tropical and subtropical regions using LCA methodologies [4]. These reports include bill of quantities, plans, performance analysis, and lifespan of the studied shelters. The data from these reports was used to develop the Life Cycle Inventories (LCI. All the amounts were converted from their original units (length, volume and amount into mass (kg units and the transport distance into ton×km. These LCIs represent the production phases of each shelter and the transportation distances for the construction materials. Two types of distances were included, local (road and international (freight ship, which were estimated based on the area of the country of study. Furthermore, the digital visualization of the shelters is presented for each of the 20 designs. Moreover, this data article presents a summary of the results for the categories Environment, Cost and Risk and the contribution to the environmental impact from the different building components of each shelter. These results are related to the article “Global or local construction materials for post-disaster reconstruction? Sustainability assessment of 20 post-disaster shelter designs”[5

The Spanish Gas Market: Demand Trends Post Recession and Consequences for the Industry

OpenAIRE

2011-01-01

In parallel with a flourishing economy, the natural gas industry in Spain was characterised by rapid consumption growth in the late 1990s and 2000s. Infrastructure and supplies were designed to meet the needs of a gas market growing at double digit rates each year. This high growth rate – for a European gas market – was expected to continue until at least the mid-2010s. By 2011, this outlook was replaced by a more pessimistic one. Firstly, the country’s economy was hit hard by the global rece...

Linking Entrepreneurial Orientation to Firm Performance in a Post-Socialist Market Context: the Case of Hungary

Directory of Open Access Journals (Sweden)

David KOVACS

2016-12-01

Full Text Available Entrepreneurial orientation provoked the interest of numerous scholars as well as political and administrative decision-makers. Both start-ups and already established corporate entities are increasingly persecuting new opportunities, products, and business models in order to establish superiority above their competitive environment. The tendencies evince an optimist impact of entrepreneurial orientation on business performance, namely on financial performance. Beyond the aforementioned relationship, there are impulses such as environmental and organizational factors, which are affecting the businesses. The results of this study provide evidence of the effect of entrepreneurial orientation on business performance in a post-socialist context. We test the impact of three moderators on this bivariate relationship. In contrast to the substantial body of literature for Western markets, we contribute to minimizing the considerable gap of research in post-socialist economies. Entrepreneurial orientation as an organizational behavior may affect the financial performance of businesses differently in distinct market contexts. Both, internal and external factors are crucial to identifying, analyze and monitor, to achieve superior performance and to overcome competitors. This study builds upon a stratified sampling survey of Hungarian company owners and managers from the Amadeus database. The study uses a deductive approach. For the analysis, we rely on structural equation modeling using the PLS algorithm. Our study contributes to the existing literature by means of confirming the entrepreneurial orientation to firm performance relationship for Hungary. In this context, we test the moderating effects of environmental dynamism, environmental hostility as environmental factors and firm age as an organizational factor. Environmental hostility is closely related to an unfavorable environment, deriving from rapid and radical changes in the industry, which are

Integration of Financial Markets in Post Global Financial Crises and Implications for British Financial Sector: Analysis Based on A Panel VAR Model

OpenAIRE

Nasir, M; Du, M

2017-01-01

This study analyses the dynamics of integration among global financial markets in the context of Global Financial Crisis (2008) by employing a Panel Vector Autoregressive (VAR) model on the monthly data of nine countries and three markets from Jan 2003 to Oct 2015. It was found that there has been a shift in the association among the global financial markets since Global Financial Crisis (GFC).Moreover, the British financial sectors in Post-GFC world clearly showed a change in the association...

Grouping Notes Through NodesThe Functions of Post-It™ Notes in Design Team Cognition

DEFF Research Database (Denmark)

Dove, Graham; Abildgaard, Sille Julie; Biskjaer, Michael Mose

The Post-It™ note is a frequently used, and yet seldom studied, design material. We investigate the functions Post-It™ notes serve when providing cognitive support for creative design team practice. Our investigation considers the ways in which Post-It™ notes function as design externalisations......, both individually and when grouped, and their role in categorisation in semantic long-term memory. To do this, we adopt a multimodal analytical approach focusing on interaction between humans, and between humans and artefacts, alongside language. We discuss in detail examples of four different...... externalisation functions served by Post-It™ notes, and show how these functions are present in complex overlapping combinations rather than being discrete. We then show how the temporal development of Post-It™ note interactions supports categorisation qualities of semantic long-term memory....

[Guidance of FDA risk evaluation and mitigation strategy and enlightenment to drug risk management of post-marketing Chinese medicine].

Science.gov (United States)

Li, Yuanyuan; Xie, Yanming

2011-10-01

The FDA risk evaluation and mitigation strategy (REMS) aims to drugs or biological products known or potential serious risk management. Analysis with the example of the content of the Onsolis REMS named FOCOS. Our country can be reference for the analysis of relevant experience and establish a scientific evaluation mechanism, strengthen the drug risk consciousness, promote the rational drug use, organic combined with the before-marketing and post-marketing evaluation of traditional Chinese medicine, and promote the evaluation of risk management of the drug development and improvement.

Adopting a Design-Thinking Multidisciplinary Learning Approach: Integrating Mobile Applications into a Marketing Research Course

Science.gov (United States)

Zarzosa, Jennifer

2018-01-01

This article seeks to address the gap between marketing education and marketing practice by integrating a design-thinking (DT) methodology to the marketing research (MR) framework to achieve learning objectives that will enhance cross-functional, collaborative, conceptual, and technical skills. The mobile application marketing research project…

Clinical data miner: an electronic case report form system with integrated data preprocessing and machine-learning libraries supporting clinical diagnostic model research.

Science.gov (United States)

Installé, Arnaud Jf; Van den Bosch, Thierry; De Moor, Bart; Timmerman, Dirk

2014-10-20

Using machine-learning techniques, clinical diagnostic model research extracts diagnostic models from patient data. Traditionally, patient data are often collected using electronic Case Report Form (eCRF) systems, while mathematical software is used for analyzing these data using machine-learning techniques. Due to the lack of integration between eCRF systems and mathematical software, extracting diagnostic models is a complex, error-prone process. Moreover, due to the complexity of this process, it is usually only performed once, after a predetermined number of data points have been collected, without insight into the predictive performance of the resulting models. The objective of the study of Clinical Data Miner (CDM) software framework is to offer an eCRF system with integrated data preprocessing and machine-learning libraries, improving efficiency of the clinical diagnostic model research workflow, and to enable optimization of patient inclusion numbers through study performance monitoring. The CDM software framework was developed using a test-driven development (TDD) approach, to ensure high software quality. Architecturally, CDM's design is split over a number of modules, to ensure future extendability. The TDD approach has enabled us to deliver high software quality. CDM's eCRF Web interface is in active use by the studies of the International Endometrial Tumor Analysis consortium, with over 4000 enrolled patients, and more studies planned. Additionally, a derived user interface has been used in six separate interrater agreement studies. CDM's integrated data preprocessing and machine-learning libraries simplify some otherwise manual and error-prone steps in the clinical diagnostic model research workflow. Furthermore, CDM's libraries provide study coordinators with a method to monitor a study's predictive performance as patient inclusions increase. To our knowledge, CDM is the only eCRF system integrating data preprocessing and machine-learning libraries

Marketing information system online design for craftsmen small medium enterprises (case study: craftsmen ac)

Science.gov (United States)

Fitriana, Rina; Kurniawan, Wawan; Barlianto, Anung; Adriansyah Putra, Rizki

2016-02-01

AC is small and medium enterprises which is engaged in the field of crafts. This SME (Small Medium Enterprise) didn't have an integrated information system for managing sales. This research aims to design a marketing Information system online as applications that built as web base. The integrated system is made to manage sales and expand its market share. This study uses a structured analysis and design in its approach to build systems and also implemented a marketing framework of STP (Segmentation, Targeting, Positioning) and 4P (Price, Product, Place, Promotion) to obtain market analysis. The main market target customer craftsmen AC is women aged 13 years to 35 years. The products produced by AC are shoes, brooch, that are typical of the archipelago. The prices is range from Rp. 2000 until Rp. 400.000. Marketing information system online can be used as a sales transaction document, promoting the goods, and for customer booking products.

The role of product design in consumers' choices in the individual insurance market.

Science.gov (United States)

Marquis, M Susan; Buntin, Melinda Beeuwkes; Escarce, José J; Kapur, Kanika

2007-12-01

To evaluate the role of health plan benefit design and price on consumers' decisions to purchase health insurance in the nongroup market and their choice of plan. Administrative data from the three largest nongroup insurers in California and survey data about those insured in the nongroup market and the uninsured in California. We fit a nested logit model to examine the effects of plan characteristics on consumer choice while accounting for substitutability among certain groups of products. Product choice is quite sensitive to price. A 10 percent decrease in the price of a product would increase its market share by about 20 percent. However, a 10 percent decrease in prices of all products would only increase overall market participation by about 4 percent. Changes in the generosity of coverage will also affect product choice, but have only small effects on overall participation. A 20 percent decrease in the deductible or maximum out-of-pocket payment of all plans would increase participation by about 0.3-0.5 percent. Perceived information search costs and other nonprice barriers have substantial effects on purchase of nongroup coverage. Modest subsidies will have small effects on purchase in the nongroup market. New product designs with higher deductibles are likely to be more attractive to healthy purchasers, but the new benefit designs are likely to have only small effects on market participation. In contrast, consumer education efforts have a role to play in helping to expand coverage.

Global electricity transformation: The critical need for integrated market design and risk management research

International Nuclear Information System (INIS)

Hung-po Chao

2006-01-01

The past three decades transformed the electricity industry. The essential goals of liberalization have been to lower costs, improve reliability, and stimulate investment and innovations through establishment of competitive electricity markets, while also relying on market mechanisms to provide creative solutions to environmental and security problems. In many instances, these goals have been achieved, but the occurrence of some spectacular market failures have brought into question the whole restructuring effort. This paper reviews recent experiences with market reform and concludes that a significant cause of failure has been the rush to unbundle vertically integrated utilities without sufficient consideration of alternative ways to manage the risk of electricity market restructuring. In particular, there is a critical need for integrated market design and risk management research to improve the process of market transformation by taking a more evolutionary approach to discover a 'Third Way' above vertical integration and full unbundling. Such research can offer a crucial feedback link to the restructuring process by identifying important lessons to be learned from past experience and developing new analytical tools to help introduce more successful market designs for the future. (author)

Marketing Strategy and Implementation

Energy Technology Data Exchange (ETDEWEB)

None

2010-05-31

This report documents the marketing campaign that has been designed for middle and high school students in New Mexico to increase interest in participation in national security careers at the National Nuclear Security Administration. This marketing campaign builds on the research that was previously conducted, as well as the focus groups that were conducted. This work is a part of the National Nuclear Security Preparedness Project (NSPP) being performed under a Department of Energy (DOE) / National Nuclear Security Administration (NNSA) grant. Outcome analysis was performed to determine appropriate marketing strategies. The analysis was based upon focus groups with middle school and high school students, student interactions, and surveys completed by students to understand and gauge student interest in Science, Technology, Engineering, and Math (STEM) subjects, interest in careers at NNSA, future job considerations, and student desire to pursue post-secondary education. Further, through the focus groups, students were asked to attend a presentation on NNSA job opportunities and employee requirements. The feedback received from the students was utilized to develop the focus and components of the marketing campaign.

The design paradox: the contribution of in-house and external design activities on product market performance

OpenAIRE

Czarnitzki, Dirk; Thorwarth, Susanne

2009-01-01

This paper explores the contribution of design activities on product market performance of Belgian companies. While there is mounting evidence that design can be seen as a strategic tool to successfully spur sales of new product developments at the firm level, the topic of design innovation has not been linked to the open innovation concept yet. In this paper we empirically test whether design activities conducted in-house differ in their contribution to new product sales from externally acqu...

[Study on building index system of risk assessment of post-marketing Chinese patent medicine based on AHP-fuzzy neural network].

Science.gov (United States)

Li, Yuanyuan; Xie, Yanming; Fu, Yingkun

2011-10-01

Currently massive researches have been launched about the safety, efficiency and economy of post-marketing Chinese patent medicine (CPM) proprietary Chinese medicine, but it was lack of a comprehensive interpretation. Establishing the risk evaluation index system and risk assessment model of CPM is the key to solve drug safety problems and protect people's health. The clinical risk factors of CPM exist similarities with the Western medicine, can draw lessons from foreign experience, but also have itself multi-factor multivariate multi-level complex features. Drug safety risk assessment for the uncertainty and complexity, using analytic hierarchy process (AHP) to empower the index weights, AHP-based fuzzy neural network to build post-marketing CPM risk evaluation index system and risk assessment model and constantly improving the application of traditional Chinese medicine characteristic is accord with the road and feasible beneficial exploration.

Using Research Case Studies in eCommerce Marketing Courses: Customer Satisfaction at Point-of-Purchase and Post-Purchase

Science.gov (United States)

Nawi, Noorshella Che; Fong, Michelle; Tatnall, Arthur

2014-01-01

This paper describes a research case study of Internet apparel marketing by small businesses in Malaysia which can beneficially be included in postgraduate business courses for understanding the importance of measuring customer satisfaction at point-of-purchase and post-purchase in online purchases. The sample size in this research is 154…

[Post-marketing surveillance on Guizhi Fuling Jiaonang based on literature review].

Science.gov (United States)

Wang, Gui-Qian; Gao, Yang; Liu, Fu-Mei; Wei, Rui-Li; Xie, Yan-Ming

2018-02-01

To systemically evaluate the post-marketing safety of Guizhi Fuling Jiaonang. Computer retrieval was conducted in Medline, EMbase, the Web of Science, Clinical Trials. Gov, the Cochrane Library, CNKI, VIP, WanFang Data and CBM to collect relevant information. The papers were then screened according to inclusion and exclusion criteria. A total of 234 papers were included in this study, including 164 randomized controlled trials, 7 quasi-randomized controlled trials, 8 non-randomized controls, 56 case series, and 1 cohort study. The patients were only treated with Guizhi Fuling Jiaonang in 56 studies, and Guizhi Fuling Jiaonang was combined with other drugs in 178 studies. The total ADRs/AEs incidence was 1.99% in single use of Guizhi Fuling Jiaonang, and 8.21% in combined use, but showing no severe adverse reactions. Gastrointestinal system damage was most common in mild ADRs. In this study, it was found that the overall safety of Guizhi Fuling Jiaonang was acceptable. The direct evidences of the drug's safety case reports were systematically analyzed in this study, but the mechanism study on the safety of the drug after marketing or the prospective long-term clinical observation study was not sufficient, so the further studies on the safety of drug use should be conducted in order to provide better guidance for clinical medication. Copyright© by the Chinese Pharmaceutical Association.

Transitioning from first- to second-generation biosimilars: An appraisal of regulatory and post-marketing challenges.

Science.gov (United States)

Blandizzi, Corrado; Galeazzi, Mauro; Valesini, Guido

2018-02-01

Second-generation biosimilars (i.e. monoclonal antibodies or proteins generated by fusion of antibody and receptor moieties) differ in several respects as compared to first-generation ones (e.g. epoetins, bone marrow stimulating factors, somatotropins). In this respect, as second-generation biosimilars are endowed with much greater structural and molecular complexity, which might translate into a number of pharmacological and therapeutic issues, they raise new challenges for manufacturers and regulatory authorities as well as new concerns for clinicians. Based on these arguments, the present article was intended to review information on the main differences between first- and second-generation biosimilars for treatment of immune-mediated inflammatory diseases, as well as their impact on immunogenicity, the design of clinical trials and the critical issue of extrapolation of therapeutic indications. The positions taken by relevant medical associations and the crucial role of pharmacovigilance are also reviewed. According to current knowledge, the initial post-marketing clinical experience with second-generation biosimilars is providing encouraging results, though their long-term safety and efficacy as well as the scientific basis underlying the extrapolation of therapeutic indications are still matter of discussion. There is some consensus that marketing applications should rely on studies supporting the clinical use of biosimilars in their different target diseases and patient populations. In parallel, clinical safety must be ensured by a strict control of the manufacturing processes and a solid pharmacovigilance program. It remains then a responsibility of the physician to drive a proper use of second-generation biosimilars into clinical practice, in accordance with guidelines issued by scientific societies. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

Auction design for the wireless spectrum market

CERN Document Server

Lin, Peng; Zhang, Qian

2014-01-01

This Brief introduces the wireless spectrum market and discusses the current research for spectrum auctions. It covers the unique properties of spectrum auction, such as interference relationship, reusability, divisibility, composite effect and marginal effect, while also proposing how to build economic incentives into the network architecture and protocols in order to optimize the efficiency of wireless systems.Three scenarios for designing new auctions are demonstrated. First, a truthful double auction scheme for spectrum trading considering both the heterogeneous propagation properties of c

Use of carabids for the post-market environmental monitoring of genetically modified crops

Czech Academy of Sciences Publication Activity Database

Skoková Habuštová, Oxana; Svobodová, Zdeňka; Cagáň, Ľ.; Sehnal, František

2017-01-01

Roč. 9, č. 4 (2017), č. článku 121. E-ISSN 2072-6651 R&D Projects: GA MŠk(CZ) 7AMB14SK096 Grant - others:projekt VEGA(SK) 1/0732/14; GA ČR(CZ) L200961652 Institutional support: RVO:60077344 Keywords : Carabidae * surrogate * post-market environmental monitoring Subject RIV: GF - Plant Pathology, Vermin, Weed, Plant Protection OBOR OECD: GM technology (crops and livestock), livestock cloning, marker assisted selection, diagnostics (DNA chips and biosensing devices for the early/accurate detection of diseases) biomass feedstock production technologies, biopharming Impact factor: 3.030, year: 2016 http://www.mdpi.com/2072-6651/9/4/121

Competitive Supply Chain Network Design Considering Marketing Strategies: A Hybrid Metaheuristic Algorithm

Directory of Open Access Journals (Sweden)

Ali Akbar Hasani

2016-11-01

Full Text Available In this paper, a comprehensive model is proposed to design a network for multi-period, multi-echelon, and multi-product inventory controlled the supply chain. Various marketing strategies and guerrilla marketing approaches are considered in the design process under the static competition condition. The goal of the proposed model is to efficiently respond to the customers’ demands in the presence of the pre-existing competitors and the price inelasticity of demands. The proposed optimization model considers multiple objectives that incorporate both market share and total profit of the considered supply chain network, simultaneously. To tackle the proposed multi-objective mixed-integer nonlinear programming model, an efficient hybrid meta-heuristic algorithm is developed that incorporates a Taguchi-based non-dominated sorting genetic algorithm-II and a particle swarm optimization. A variable neighborhood decomposition search is applied to enhance a local search process of the proposed hybrid solution algorithm. Computational results illustrate that the proposed model and solution algorithm are notably efficient in dealing with the competitive pressure by adopting the proper marketing strategies.

Designing realized kernels to measure the ex post variation of equity prices in the presence of noise

DEFF Research Database (Denmark)

Barndorff-Nielsen, Ole Eiler; Hansen, P.R.; Lunde, Asger

2008-01-01

This paper shows how to use realized kernels to carry out efficient feasible inference on the ex post variation of underlying equity prices in the presence of simple models of market frictions. The weights can be chosen to achieve the best possible rate of convergence and to have an asymptotic va......) allow for temporally dependent noise. The finite sample performance of our estimators is studied using simulation, while empirical work illustrates their use in practice.......This paper shows how to use realized kernels to carry out efficient feasible inference on the ex post variation of underlying equity prices in the presence of simple models of market frictions. The weights can be chosen to achieve the best possible rate of convergence and to have an asymptotic...... variance which equals that of the maximum likelihood estimator in the parametric version of this problem. Realized kernels can also be selected to (i) be analyzed using endogenously spaced data such as that in data bases on transactions, (ii) allow for market frictions which are endogenous, and (iii...

Elements of design and aesthetics on the beer market in Romania. Case Study: Tuborg

Directory of Open Access Journals (Sweden)

Anca MADAR

2015-12-01

Full Text Available Due to the development and modernization of trade, the packaging is a very valuable component of marketing policy, being a carrier of messages to the consumer. Classic elements of design that include any packaging refer to the shape, colour and graphics. The beer market in Romania was marked by originality and innovation in terms of packaging design elements. Tuborg is the leading brand in the portfolio of URBB and the first Tuborg beer bottle was produced in Romania in 1997. The Tubog beer is identified on the market by a special package that was always improved.

Vocations: The Link between Post-Compulsory Education and the Labour Market. What the Research Says For... Qualification & Approval Bodies

Science.gov (United States)

Wheelahan, Leesa; Buchanan, John; Yu, Serena

2015-01-01

This summary pulls together the relevant key findings for qualification and approval bodies from the research program "Vocations: The Link between Post-Compulsory Education and the Labour Market." The program was comprised of three different strands: (1) pathways from VET in Schools, (2) pathways within and between vocational education…

Performance of the ITER ECRF launchers

International Nuclear Information System (INIS)

Lloyd, Brian; Warrick, Chris; O'Brien, Martin

2003-01-01

The Fokker-Planck code BANDIT-3D has been used to explore the heating and current drive capabilities of electron cyclotron waves in ITER. Calculations have been carried out for both the upper launcher and the mid-plane launcher designs. BANDIT-3D is a relativistic and self-consistent ray tracing and Fokker-Planck code incorporating 2D velocity space (generalized speed and pitch angle) and 1D real space effects. Electron radial diffusion, trapping, toroidal dc electric fields and realistic magnetic geometry (e.g. up-down asymmetric single null divertor configuration) can all be included and synergy with other schemes can be studied. It has been found that the effective poloidal steering range for the upper launcher is limited by loss of current localisation at large poloidal angle α (most severe for the upper rows of the launcher) and by electron trapping effects at low α where deposition is at large r/a. Electron trapping eventually leads to a reversal of the driven current at large minor radius due to the Ohkawa effect. The effectiveness of the upper launcher for NTM suppression will strongly depend on the rational surface location and local temperature. The extreme geometry and limited steering range mean that performance will be fairly intolerant to variations in magnetic configuration. Calculations for the mid-plane launcher show that absorption is restricted to r/a < 0.5 for the reference equilibrium employed and current drive efficiencies are comparable to those previously calculated for RTO/RCITER. (authors)

Computer Security: posting and mis-posting

CERN Multimedia

Stefan Lueders, Computer Security Team

2015-01-01

This is what can happen at CERN if you don't lock your computer screen...   “Hi, I am looking for a partner either male or female to attend salsa lessons. I have a great body and enjoy rubbing it against other people on the dance floor. I would consider dinner after with the right person. If you think you can keep up with me and enjoy getting sweaty send me a reply. Stay sexy…” This is the original text of a recent posting on the CERN Market webpage. Some people might find this appealing, some people think this is funny. Personally, I couldn’t care less. But professionally, we had to follow up as this text can be perceived as inappropriate and, thus, in violation of the Terms of Usage of the CERN Market as well as the CERN Computing Rules and its annex on private usage of the CERN computing facilities. We remind you that the CERN Market is a public website that can be used by people within but also outside CERN. All posts are visible world...

Post-Purchase Evaluation in the Smartphone Market: An Investigation into Cognitive Dissonance among iPhone and Other Smartphone Brand Owners

OpenAIRE

Kraappa, Anna

2011-01-01

Purpose The main objective was to investigate whether iPhone owners experienced less cognitive post-purchase dissonance than other brand owners and was this due to the marketing communications efforts of Apple Inc., from hereon called Apple. Finally, the influence of Web 2.0 in the process of post-purchase evaluation was examined. Web 2.0 is a version of the Internet and it encourages towards user engagement on websites such as Facebook. Methodology A critical review of the litera...

Capacity Market Design: Motivation and Challenges in Alberta’s Electricity Market

OpenAIRE

David Brown

2018-01-01

Alberta’s electricity market is currently undergoing a period of substantial transition. The province should proceed with caution as it switches from an energy-only electricity market to a capacity market by 2021. Many other jurisdictions have already made the changeover and Alberta can learn from their experiences in order to avoid common mistakes and pitfalls that can arise with the deployment of a capacity market.There were growing concerns that the existing electricity market structure wo...

New content, design, and marketing trends in commercial publishing

Directory of Open Access Journals (Sweden)

Leonardo Blažević

2009-07-01

Full Text Available The aim of the paper is to analyse the actual status of book publishing in Croatia, envisage the trends of its future development and, by analyzing the current state of affairs and new book marketing trends, draw conclusions as to which directions the publishing companies should take in order to survive on the market. The aims stated as such result from the author’s research and review of the business operations of the ‘Naklada Ljevak’ publishing company, and from the monitoring of relevant home and foreign literature in the field of marketing in general as well as specialized book marketing literature. In the introductory part the author defines publishing and its amphibious nature that lies in the fact that publishing is at the same time the process of creation and distribution of knowledge and culture, as well as a business resulting in education, as well as in entertainment. The following chapter offers an explanation of the most important facts required to understand the current publishing marketing (globalization, huge sales chains, fierce competition, ever lower standard of living in Croatia… and lists the marketing programme elements applicable to publishing. Further on, the focus shifts on the book as a product and a part of publishing marketing. It mentions the economic and business trends that have affected the development of publishing as an industry over the past sixty years, and the book as a product. New book content trends have been elaborated as well: novels on exotic countries, current affairs issues, autobiographies and biographies, self-help manuals and titles offering ‘instant-knowledge’. There is a definition and explanation of trends that relate to the book as a material product such as cover design, format, binding, types of print paper and technical features such as layout, margins, font size and spacing. 

Design and Promotion Strategy of Marketing Platform of Aquatic Auction based on Internet

Science.gov (United States)

Peng, Jianliang

For the online trade and promotion of aquatic products and related materials through the network between supply and demand, the design content and effective promotional strategies of aquatic auctions online marketing platform is proposed in this paper. Design elements involve the location of customer service, the basic function of the platform including the purchase of general orders, online auctions, information dissemination, and recommendation of fine products, human services, and payment preferences. Based on network and mobile e-commerce transaction support, the auction platform makes the transaction of aquatic products well in advance. The results are important practical value for the design and application of online marketing platform of aquatic auction.

Vocations: The Link between Post-Compulsory Education and the Labour Market. What the Research Says For... Government & Policy-Makers

Science.gov (United States)

Wheelahan, Leesa; Buchanan, John; Yu, Serena

2015-01-01

This summary brings together the relevant key findings for government and policy-makers from the research program "Vocations: The Link between Post-Compulsory Education and the Labour Market." The program was comprised of three different strands: (1) pathways from VET in Schools, (2) pathways within and between vocational education and…

Post Millennium Urban Space Design in Denmark

DEFF Research Database (Denmark)

Kiib, Hans

Hans Kiib Post Millennium Urban Space Design in Denmark - a survey on 100 Danish projects from 2002 – 2010. This article is based on an evaluation of 100 Danish open space projects form 2000 – 2010. The projects was initially proposals from Danish municipalities for the Campaign on Better Open...... Spaces (Bedre Byrums Kampagne) run by Realdania stating in 2002. These projects are all proposed just after 2002. Based on the quality of the projects including the goals for the proposal, the quality of the proposed design, and finally to what extent the projects contributed to new concepts...... and perspectives in open space design, 24 proposals were selected for further development. These projects were developed in the period from 2003 – 2007 with support from consultants. The evaluation has been carried out in 2011. It categorizes the initial 100 projects in relation to location, goals, concepts, scale...

Capacity market design and renewable energy: Performance incentives, qualifying capacity, and demand curves

Energy Technology Data Exchange (ETDEWEB)

Botterud, Audun; Levin, Todd; Byers, Conleigh

2018-01-01

A review of capacity markets in the United States in the context of increasing levels of variable renewable energy finds substantial differences with respect to incentives for operational performance, methods to calculate qualifying capacity for variable renewable energy and energy storage, and demand curves for capacity. The review also reveals large differences in historical capacity market clearing prices. The authors conclude that electricity market design must continue to evolve to achieve cost-effective policies for resource adequacy.

Philippines' experience in marketing irradiated foods

International Nuclear Information System (INIS)

Lustre, A. O.; Ang, L.; Dianco, A.

1985-01-01

The Food Terminal Inc. in Manila, in cooperation with the Philippine Atomic Energy Agency and with funding support from the International Atomic Energy Agency in Vienna has been conducting storage and marketing studies on onions, garlic and mangoes. The objective is to gather loss reduction data and consumer reaction information that can serve as a basis for evaluating the risks and benefits involved in the establishment of a commercial food irradiator in the country. These studies show that irradiation reduces low-temperature storage losses in onions and garlic by 10-40% and post-storage marketing losses at ambient conditions by 16-50% in onions. Post-storage marketing trials not only indicate a significant reduction in losses during shipping and retail sale but a large increase in the marketability of irradiated commodities as measured by the rate of sale of the commodity and the price which it commands during the selling period. No adverse consumer reaction occurred during the sale of irradiated foods labelled as such except for a few comments indicating fear, ignorance and/or curiosity. The importance of irradiation as a substitute quarantine treatment for mangoes and for eliminating Salmonella in frozen foods for export is discussed in relation to the growing importance of these commodities to the Philippines' non-traditional export markets. Other applications of irradiation that could result in a perceptible improvement in the marketability of food commodities in the Philippines are discussed. Marketing studies are invaluable in evaluating the potential benefits of a new technology as food irradiation. In view of this, there is great interest in the completion of a pilot plant for food irradiation by the Philippine Atomic Energy Commission. The design and capacity of this plant are discussed

Clinical outcomes with daptomycin: a post-marketing, real-world evaluation.

Science.gov (United States)

Sakoulas, G

2009-12-01

The Cubicin Outcomes Registry and Experience (CORE) is an ongoing, retrospective, post-marketing database of daptomycin use in the USA. Although non-comparative, CORE offers insight into real-life clinical experience with daptomycin in various Gram-positive infections and specific patient types. Analyses of daptomycin treatment outcomes using the CORE database revealed that treatment with daptomycin has resulted in high rates of clinical success for a variety of Gram-positive infections, including indicated infections such as complicated skin and soft tissue infections, Staphylococcus aureus bacteraemia and right-sided infective endocarditis, and non-indicated infections such as osteomyelitis. Treatment outcomes did not differ significantly according to the causative pathogen for any of the analyses performed and were not influenced by the vancomycin MIC. Patients frequently received therapy with alternative antibiotics prior to treatment with daptomycin, particularly those patients with more serious infections. However, similar treatment outcomes were observed when daptomycin was used as first-line therapy or as salvage therapy, demonstrating the effectiveness of daptomycin in the treatment of these patients.

Displacement in new economy labor markets: Post-displacement wage loss in high tech versus low tech cities.

Science.gov (United States)

Davis, Daniel J; Rubin, Beth A

2016-11-01

While scholars and politicians tout education as the salve to employment disruptions, we argue that the geography of the new economy, and the social closure mechanisms that geography creates, may be just as important as individuals' characteristics for predicting post-displacement wage loss (or gain). We use data from the 2012 Displaced Workers ement of the Current Population Survey and from the 2010 United States Census to test hypotheses linking local labor markets in different industrial contexts to post-displacement wage loss. Our results point to age as a closure mechanism, and to the partially protective effect of education in high-tech versus low-tech economic sectors. This study is the first to use national level data to examine how employment in high-tech cities influences post-displacement wages. These findings are relevant both for theorizing about the new economy and for public policy. Copyright © 2016 Elsevier Inc. All rights reserved.

Government intervention and market integration in Indonesian rice markets

OpenAIRE

Ismet, Mohammad; Barkley, Andrew P.; Llewelyn, Richard V.

1998-01-01

Long-run spatial price relationships in Indonesian rice markets and factors affecting the degree of market integration are evaluated using multivariate cointegration tests with weekly price data for the 1982-1993 period. The analysis includes evaluation of pre-self-sufficiency and post-self-sufficiency periods as well as for the entire period. The cointegration tests for entire Indonesian rice market, represented by the nine most relevant price series, indicate that relative to the pre-selfsu...

Environmental change challenges decision-making during post-market environmental monitoring of transgenic crops.

Science.gov (United States)

Sanvido, Olivier; Romeis, Jörg; Bigler, Franz

2011-12-01

The ability to decide what kind of environmental changes observed during post-market environmental monitoring of genetically modified (GM) crops represent environmental harm is an essential part of most legal frameworks regulating the commercial release of GM crops into the environment. Among others, such decisions are necessary to initiate remedial measures or to sustain claims of redress linked to environmental liability. Given that consensus on criteria to evaluate 'environmental harm' has not yet been found, there are a number of challenges for risk managers when interpreting GM crop monitoring data for environmental decision-making. In the present paper, we argue that the challenges in decision-making have four main causes. The first three causes relate to scientific data collection and analysis, which have methodological limits. The forth cause concerns scientific data evaluation, which is controversial among the different stakeholders involved in the debate on potential impacts of GM crops on the environment. This results in controversy how the effects of GM crops should be valued and what constitutes environmental harm. This controversy may influence decision-making about triggering corrective actions by regulators. We analyse all four challenges and propose potential strategies for addressing them. We conclude that environmental monitoring has its limits in reducing uncertainties remaining from the environmental risk assessment prior to market approval. We argue that remaining uncertainties related to adverse environmental effects of GM crops would probably be assessed in a more efficient and rigorous way during pre-market risk assessment. Risk managers should acknowledge the limits of environmental monitoring programmes as a tool for decision-making.

The marketing implications of affective product design.

Science.gov (United States)

Seva, Rosemary R; Duh, Henry Been-Lirn; Helander, Martin G

2007-11-01

Emotions are compelling human experiences and product designers can take advantage of this by conceptualizing emotion-engendering products that sell well in the market. This study hypothesized that product attributes influence users' emotions and that the relationship is moderated by the adherence of these product attributes to purchase criteria. It was further hypothesized that the emotional experience of the user influences purchase intention. A laboratory study was conducted to validate the hypotheses using mobile phones as test products. Sixty-two participants were asked to assess eight phones from a display of 10 phones and indicate their emotional experiences after assessment. Results suggest that some product attributes can cause intense emotional experience. The attributes relate to the phone's dimensions and the relationship between these dimensions. The study validated the notion of integrating affect in designing products that convey users' personalities.

CRE answer to the European Commission public consultation on the new electricity market design

International Nuclear Information System (INIS)

Ladoucette, Philippe de

2015-01-01

On July 15, 2015, the European Commission launched a public consultation on the new Electricity Market Design. All National Regulatory Authorities (NRAs), and CRE in particular, contributed to the joint ACER-CEER response to the consultation. CRE supports this joint response, and further develops some topics in this document, building on its particular experience in the implementation of the internal energy market: implementation of the network codes, in particular those regarding the markets, development of demand-side flexibility, development of interconnections, and alignment of fragmented balancing markets

Design and Measurement of Metallic Post-Wall Waveguide Components

NARCIS (Netherlands)

Coenen, T.J.; Bekers, D.J.; Tauritz, J.L.; Vliet, F.E. van

2009-01-01

Abstract—In this paper we discuss the design and measurement of a set of metallic post-wall waveguide components for antenna feed structures. The components are manufactured on a single layer printed circuit board and excited by a grounded coplanar waveguide. For a straight transmission line, a 90°

Designing the marketing-sales interface in B2B firms

NARCIS (Netherlands)

Biemans, W.G.; Makovec Brencic, M.

2007-01-01

Purpose - This paper explores the marketing-sales interface in Dutch and Slovenian B2B firms. Design/methodology/approach - The study included 11 Dutch firms and ten Slovenian firms, with both samples as closely matched as possible. The firms were all manufacturers of physical products that operate

Reevaluation of the post-marketing safety of Shuxuening injection based on real-world and evidence-based evaluations

Directory of Open Access Journals (Sweden)

Wang C

2018-04-01

Full Text Available Can Wang,1,2 Qing-ping Shi,1,2 Feng Ding,2 Xiao-dong Jiang,1,2 Wei Tang,3 Mei-Ling Yu,1,2 Jian-Hua Zhu2 1Department of Pharmacy, The First Affiliated Hospital of Bengbu Medical College, Bengbu, People’s Republic of China; 2Faculty of Pharmacy, Bengbu Medical College, Bengbu, People’s Republic of China; 3Department of Pharmacy, Huaiyuan County Hospital of TCM in Anhui, Bengbu, People’s Republic of China Aim: To evaluate the factors influencing suspected hypersensitivity and adverse systemic reactions after Shuxuening injection and to provide innovative ideas and methods for the reevaluation of post-marketing safety of Shuxuening.Methods: This study used a prospective, nested case–control study design, combined with a prescription sequence analysis design method. It classified patients who exhibited trigger signals after administration of Shuxuening injection as suspected allergic patients and made comparisons with patients who did not report adverse effects to calculate the correlation between relevant risk factors and suspected allergic reactions. Randomized controlled studies and cohort studies of the adverse drug reaction (ADR of Shuxuening were performed using a computer database. Data retrieval was carried out by the foundation governing the individual database. Meta-analysis was performed by using R3.2.3 software to evaluate the ADRs of Shuxuening.Results: The results of real-world study showed that administration of Shuxuening in combination with potassium aspartate and magnesium, atorvastatin calcium, Shengmai injection, pantoprazole sodium, or high-dose medication was a risk factor for suspected allergic reactions. Meta-analysis showed that the incidence of adverse events was 5.84% (95% CI 0.0499; 0.0674, and serious adverse reaction rate was 4.36% (95% CI 0.0188; 0.0760 when Shuxuening was used in combination with these drugs. The incidence of allergic reaction was also influenced by the vehicle, duration of treatment, single

Auction Design for the Allocation of Emission Permits in the Presence of Market Power

International Nuclear Information System (INIS)

Sunnevaag, K.J.

2003-01-01

To the extent that emission permits have been allocated using market mechanisms, this has been done using a sealed-bid auction design, typically with discriminatory prices. However, several authors have recommended the ascending auction format. Basically, two 'competing' ascending auction designs have been suggested, the standard ascending auction (with clock or demand schedules), or an alternative ascending-clock implementation of Vickrey-pricing. The latter design was introduced as a response to problems of bid shading under the sealed-bid and the standard ascending auction format. The purpose of this paper is to investigate the allocation of permits under these two alternative mechanisms. The auction process and the resulting market outcome in the presence of oligopolistic competition are simulated. In this setting, it is not obvious that bid shading is the optimal strategy under the standard design, nor is it obvious that sincere bidding is the optimal strategy under the alternative ascending auction design. The alternative auction format makes it less costly to pursue a strategy to increase market shares through the acquisition of emission permits, thus increasing the competitor's costs, leading to overbidding as the optimal strategy

Korea's emission trading scheme and policy design issues to achieve market-efficiency and abatement targets

International Nuclear Information System (INIS)

Park, Hojeong; Hong, Won Kyung

2014-01-01

In 2008, the government of Republic of Korea (Korea) announced the national abatement target aiming at 30% reductions from the Business-as-Usual projections by 2020. Accordingly, the Emission Trading Scheme (ETS) will be implemented from 2015 onwards. As ETS performance substantially depends on the structural design, it is critically important to examine the details of Korean ETS for the achievement of cost effectiveness and concurrent development of an active emission trading market. This paper addresses several policy design issues for this purpose. After providing an overview on the current framework of Korean ETS, we propose ways to achieve flexibility, consistency and market efficiency of the program in consideration of the preexisting policies. Issues in policy design are discussed by focusing on allowance allocation, market stabilization measures and price mechanism in the emission and energy markets in Korea. This paper will serve as a practical guideline for establishing sustainable and market-efficient Korean ETS that can be compatible with the international standards as in the EU ETS. - Highlights: • Emission Trading Scheme (ETS) will be implemented from 2015 in Korea to reduce CO 2 . • ETS performance substantially depends on structural design. • We provide policy overview on the current framework of Korean ETS. • Several policy design issues are discussed for developing policy consistency. • We focus on allowance allocation, allowance reserve and market stabilization measures

Sustainable design options for the German electricity market. A comparison of the energy-only market with capacity markets; Zukunftsfaehige Designoptionen fuer den deutschen Strommarkt. Ein Vergleich des Energy-only-Marktes mit Kapazitaetsmaerkten

Energy Technology Data Exchange (ETDEWEB)

Keles, Dogan; Renz, Lea; Bublitz, Andreas; Zimmermann, Florian; Genoese, Massimo; Fichtner, Wolf [Karlsruher Institut fuer Technologie, Karlsruhe (Germany). Lehrstuhl fuer Energiewirtschaft; Hoefling, Holger; Sensfuss, Frank; Winkler, Jenny [Fraunhofer-Institut fuer System- und Innovationsforschung (ISI), Karlsruhe (Germany)

2016-04-01

This study intensively discusses the further developments of the electricity market design in Germany based on substantial scientific insights. For this purpose, an agent-based simulation model is applied to evaluate the operability of the energy only market extended with a strategic reserve. Furthermore, the effects of the implementation of a centralized or decentralized capacity market are analyzed.

A new approach to measure speculation in the oil futures market and some policy implications

International Nuclear Information System (INIS)

Chan, Leo H.; Nguyen, Chi M.; Chan, Kam C.

2015-01-01

We propose using a new relative measure, the speculative ratio, defined as trading volume divided by open interest, to gauge speculative activity in the oil futures market. We apply the speculative ratio to examine the relation between basis and speculative activity in the oil futures market before and after the financialization of the oil market in 2003. Our finding suggests that the oil futures market is dominated by uninformed speculators in the post-financialization period. Our finding carries several practical policy implications, as follows: (1) both the commodity exchange and the regulator should design regulations and trading policies that improve basis risk; (2) on the commodity exchange side, new policies on margin requirements and position limits for speculators should be implemented; (3) margin requirements should be based on the level of basis risk; (4) regulators should speed up implementation of the position limit rule in the Dodd–Frank Act; and (5) stronger and more meaningful enforcement actions by regulators are required to punish and deter market manipulators. - Highlights: • Use a new speculative ratio to gauge speculative activities in oil futures market. • Examine the relation between basis and speculative activities. • The new speculative ratio also works well in the post-2008 oil bubble period. • Oil futures market is dominated by uninformed speculators in post-financialization in 2003.

Political and Economic Geomorphology: The Effect of Market Forces on Stream Restoration Designs

Science.gov (United States)

Singh, J.; Doyle, M. W.; Lave, R.; Robertson, M.

2013-12-01

Stream restoration in the U.S. is increasingly driven by compensatory mitigation; impacts to streams associated with typical land development activities must be offset via restoration of streams elsewhere. This policy application creates conditions in which restored stream ';credits' are traded under market-like conditions, comparable to wetland mitigation, carbon offsets, or endangered species habitat banking. The effect of this relatively new mechanism to finance stream restoration on design and construction is unknown. This research explores whether the introduction of a credit-based mitigation apparatus results in streams designed to maximize credit yields (i.e., ';credit-chasing') rather than focusing on restoring natural systems or functions. In other words, are market-based restored streams different from those designed for non-market purposes? We quantified geomorphic characteristics (e.g. hydraulic geometry, sinuosity, profile, bed sediment, LWD) of three types of streams: (1) a random sample of non-restored reaches, (2) streams restored for compensatory mitigation, and (3) streams restored under alternative funding sources (e.g., government grant programs, non-profit activities). We also compared the location of the types of stream reaches to determine whether there is a spatiality of restored streams. Physical data were complemented with a series of semi-structured interviews with key personnel in the stream restoration industry to solicit information on the influence of policy interpretation and market-driven factors on the design process. Preliminary analysis suggests that restoration is driving a directional shift in stream morphology in North Carolina. As a simple example, in the Piedmont, non-restored and restored channels had mean sinuosity of 1.17 and 1.23, respectively (p sale of restored stream credits, was seen as critically important rather than the marginal gains to be made by manipulating particular stream designs to glean more credits

A New Higher Education Marketing Mix: The 7Ps for MBA Marketing

Science.gov (United States)

Ivy, Jonathan

2008-01-01

Purpose: The purpose of this paper is to present a new marketing mix based on MBA students' attitudes and opinions towards the marketing initiatives of business schools in South Africa. The post-graduate business education market is, and increasingly, getting more aggressive in their efforts to attract students on to their flagship degree, the…

Generic market design issues highlighted: prices soar in Alberta as capacity tightens

International Nuclear Information System (INIS)

Anon.

1999-01-01

Many Alberta consumers, alarmed by enormous price increases, are asking questions about whether electric sector restructuring in the province has progressed far enough. The average cost of power in Alberta's spot market in October were $70.46 per MWH above the $20-$30 that consumers had paid in recent years. It is widely admitted that the high prices reflect an increasingly tight supply situation in which construction of new capacity has not kept pace with growth in demand. It is a standard case of what happens when the market design focuses on promoting short-term price competition to the detriment of creating compeition in the forward markets. A debate has been produced in Alberta with major power consumers calling for a breakup of the three major generators, and the government suggesting that such intervention would be like returning to the days before competition when government tried to control everything. Competition may not work unless divestiture is revisited. There is a hard time seeing the light at the end of the restructuring tunnel for industrial consumers. Ontario's Market Design Committee struggled with the same issue, believing that an industry composed of many smaller independent generating companies was the only way to achieve lasting and meaningful price competition. The best price protection for consumers is an active and competitive investment market for new capacity, and Alberta should not repeat Ontario's mistake and leave the work until price problems develop

[Use of social marketing to increase water consumption among school-age children in Mexico City].

Science.gov (United States)

Carriedo, Ángela; Bonvecchio, Anabelle; López, Nancy; Morales, Maricruz; Mena, Carmen; Théodore, Florence L; Irizarry, Laura

2013-01-01

To increase water consumption in school children in Mexico City through a social marketing intervention. Cluster quasi-experimental design. Intervention of three months in schools, including water provision and designed based on social marketing. Reported changes in attitude, knowledge and behavior were compared pre and post intervention. Children of the intervention group (n=116) increased in 38% (171 ml) water consumption during school time, control group (n=167) decreased its consumption in 21% (140 ml) (pwater consumption among children, strategy that might contribute to mitigate childhood obesity.

Decision support methods for the detection of adverse events in post-marketing data.

Science.gov (United States)

Hauben, M; Bate, A

2009-04-01

Spontaneous reporting is a crucial component of post-marketing drug safety surveillance despite its significant limitations. The size and complexity of some spontaneous reporting system databases represent a challenge for drug safety professionals who traditionally have relied heavily on the scientific and clinical acumen of the prepared mind. Computer algorithms that calculate statistical measures of reporting frequency for huge numbers of drug-event combinations are increasingly used to support pharamcovigilance analysts screening large spontaneous reporting system databases. After an overview of pharmacovigilance and spontaneous reporting systems, we discuss the theory and application of contemporary computer algorithms in regular use, those under development, and the practical considerations involved in the implementation of computer algorithms within a comprehensive and holistic drug safety signal detection program.

University of Colorado at Boulder: Energy and Climate Revolving Fund. Green Revolving Funds in Action: Case Study Series

Science.gov (United States)

Caine, Rebecca

2012-01-01

The University of Colorado at Boulder's student run Environmental Center leads the campus' sustainability efforts. The Center created the Energy and Climate Revolving Fund (ECRF) in 2007 to finance energy-efficiency upgrades. The ECRF functions as a source of funding for project loans and provides a method of financing projects that seeks to save…

Post retention and post/core shear bond strength of four post systems.

Science.gov (United States)

Stockton, L W; Williams, P T; Clarke, C T

2000-01-01

As clinicians we continue to search for a post system which will give us maximum retention while maximizing resistance to root fracture. The introduction of several new post systems, with claims of high retentive and resistance to root fracture values, require that independent studies be performed to evaluate these claims. This study tested the tensile and shear dislodgment forces of four post designs that were luted into roots 10 mm apical of the CEJ. The Para Post Plus (P1) is a parallel-sided, passive design; the Para Post XT (P2) is a combination active/passive design; the Flexi-Post (F1) and the Flexi-Flange (F2) are active post designs. All systems tested were stainless steel. This study compared the test results of the four post designs for tensile and shear dislodgment. All mounted samples were loaded in tension until failure occurred. The tensile load was applied parallel to the long axis of the root, while the shear load was applied at 450 to the long axis of the root. The Flexi-Post (F1) was significantly different from the other three in the tensile test, however, the Para Post XT (P2) was significantly different to the other three in the shear test and had a better probability for survival in the Kaplan-Meier survival function test. Based on the results of this study, our recommendation is for the Para Post XT (P2).

Market Designs : A Survey and Analysis of Methods to Ensure Peak Capacity

OpenAIRE

Gullberg, Erik

2008-01-01

The production and consumption of electricity must be in balance in order to maintain the frequency in an electrical grid. During peak loads this may be troublesome to achieve due to lack of adequate production capabilities. Competitive electricity markets with price caps have a problem - insufficient revenues for peak production units which lead to mothballing or decommissioning of power plants. Inadequate production capability is solved through design of the electricity markets which render...

A Marketing Perspective on Mergers and Acquisitions : How Marketing Integration Affects Postmerger Performance

OpenAIRE

Homburg, Christian; Bucerius, Matthias

2004-01-01

Previous research on mergers and acquisitions (M&A) has neglected marketing issues by and large. This paper examines the effects of post merger integration (PMI) in marketing (ex tent and speed of marketing integration) on M&A performance mediated by integration outcomes (magnitude of cost savings and market-related performance). Results from a survey of 232 horizontal mergers and acquisitions show that market-related performance after the merger or acquisition has a much stronger impac...

75 FR 80571 - Core Principles and Other Requirements for Designated Contract Markets

Science.gov (United States)

2010-12-22

... Part II Commodity Futures Trading Commission 17 CFR Parts 1, 16, and 38 Core Principles and Other... CFR Parts 1, 16, and 38 RIN 3038-AD09 Core Principles and Other Requirements for Designated Contract... Principles 1. Subpart B--Designation as Contract Market 2. Subpart C--Compliance With Rules i. Proposed Sec...

Students' Preferences and Opinions on Design of a Mobile Marketing Education Application

Science.gov (United States)

Ozata, Zeynep; Ozdama Keskin, Nilgun

2014-01-01

The purpose of this study was to define and better understand business school students' opinions and preferences on the design of a mobile marketing education application. To accomplish this purpose an explanatory mixed methods study design was used and the data was collected sequentially. First, a questionnaire was conducted with 168 business…

New wholesale power market design using linked forward markets :

Energy Technology Data Exchange (ETDEWEB)

Silva Monroy, Cesar Augusto; Loose, Verne William; Ellison, James F.; Elliott, Ryan Thomas; Byrne, Raymond Harry; Guttromson, Ross; Tesfatsion, Leigh S.

2013-04-01

This report proposes a reformulation of U.S. ISO/RTO-managed wholesale electric power mar- kets for improved reliability and e ciency of system operations. Current markets do not specify or compensate primary frequency response. They also unnecessarily limit the participation of new technologies in reserve markets and o er insu cient economic inducements for new capacity invest- ment. In the proposed market reformulation, energy products are represented as physically-covered rm contracts and reserve products as physically-covered call option contracts. Trading of these products is supported by a backbone of linked ISO/RTO-managed forward markets with planning horizons ranging from multiple years to minutes ahead. A principal advantage of this reformulation is that reserve needs can be speci ed in detail, and resources can o er the services for which they are best suited, without being forced to conform to rigid reserve product de nitions. This should improve the business case for electric energy storage and other emerging technologies to provide reserve. In addition, the facilitation of price discovery should help to ensure e cient energy/reserve procurement and adequate levels of new capacity investment.

Designing a water leasing market for the Mimbres River, New Mexico.

Energy Technology Data Exchange (ETDEWEB)

Reno-Trujillo, Marissa Devan; Tidwell, Vincent Carroll; Broadbent, Craig; Brookshire, David; Coursey, Don; Jackson, Charles.; Polley, Adam; Stevenson, Bryan

2013-04-01

The objective of this study is to develop a conceptual framework for establishing water leasing markets in New Mexico using the Mimbres River as a test case. Given the past and growing stress over water in New Mexico and the Mimbres River in particular, this work will develop a mechanism for the short term, efficient, temporary transfer of water from one user to another while avoiding adverse effects on any user not directly involved in the transaction (i.e., third party effects). Toward establishing a water leasing market, five basic tasks were performed, (1) a series of stakeholder meetings were conducted to identify and address concerns and interests of basin residents, (2) several gauges were installed on irrigation ditches to aid in the monitoring and management of water resources in the basin, (3) the hydrologic/market model and decision support interface was extended to include the Middle and Lower reaches of the Mimbres River, (4) experiments were conducted to aid in design of the water leasing market, and (5) a set of rules governing a water leasing market was drafted for future adoption by basin residents and the New Mexico Office of the State Engineer.

The Analysis and the Design of E-marketing Strategy at Sme's (a Case Study: the Dare to Dream Indonesia Community)

OpenAIRE

Ongowarsito, Henkie; Nurcahyani, Kartika; Djoyo, Brata Wibawa

2011-01-01

The purposes of the research are to analyze the e-marketing strategy and to design e-marketing application which is a website that is appropriate for SME’S of Dare to Dream Indonesia (D2DI) community. The methodology of analysis used consists of 4 stages from 7 stages of e-marketing and the design method consists of three last stages of e-marketing. The result achieved is a website as an e-marketing application that can support marketing and promoting activities, expanding the target market, ...

MARKETING CHARACTERISTICS OF INSURANCE MARKET IN UKRAINE

Directory of Open Access Journals (Sweden)

А. Sabirova

2014-03-01

Full Text Available The current state of the insurance market of Ukraine in the post-crisis period, by comparison with the pre-crisis was investigated in the paper. The insurance market in the pre-crisis period grew rapidly, but was unable to withstand the economic crisis and suffered a crushing blow. The economic crisis of 2008-2009 led to a decrease of the demand for financial services in general and insurance services in particular. The lack of development of the insurance market created high barriers for responding and adapting to changes that occurred during the crisis.

Safety Profile of Eslicarbazepine Acetate as Add-On Therapy in Adults with Refractory Focal-Onset Seizures: From Clinical Studies to 6 Years of Post-Marketing Experience.

Science.gov (United States)

Gama, Helena; Vieira, Mariana; Costa, Raquel; Graça, Joana; Magalhães, Luís M; Soares-da-Silva, Patrício

2017-12-01

Eslicarbazepine acetate was first approved in the European Union in 2009 as adjunctive therapy in adults with partial-onset seizures with or without secondary generalization. The objective of this study was to review the safety profile of eslicarbazepine acetate analyzing the data from several clinical studies to 6 years of post-marketing surveillance. We used a post-hoc pooled safety analysis of four phase III, double-blind, randomized, placebo-controlled studies (BIA-2093-301, -302, -303, -304) of eslicarbazepine acetate as add-on therapy in adults. Safety data of eslicarbazepine acetate in special populations of patients aged ≥65 years with partial-onset seizures (BIA-2093-401) and subjects with moderate hepatic impairment (BIA-2093-111) and renal impairment (BIA-2093-112) are also considered. The incidences of treatment-emergent adverse events, treatment-emergent adverse events leading to discontinuation, and serious adverse events were analyzed. The global safety database of eslicarbazepine acetate was analyzed for all cases from post-marketing surveillance from 1 October, 2009 to 21 October, 2015. From a pooled analysis of four phase III studies, it was concluded that the incidence of treatment-emergent adverse events, treatment-emergent adverse events leading to discontinuation, and adverse drug reactions were dose dependent. Dizziness, somnolence, headache, and nausea were the most common treatment-emergent adverse events (≥10% of patients) and the majority were of mild-to-moderate intensity. No dose-dependent trend was observed for serious adverse events and individual serious adverse events were reported in less than 1% of patients. Hyponatremia was classified as a possibly related treatment-emergent adverse event in phase III studies (1.2%); however, after 6 years of post-marketing surveillance it represents the most frequently (10.2%) reported adverse drug reaction, with more than half of these cases occurring with eslicarbazepine acetate at

Transforming the market for residential windows: design considerations for DOE's Efficient Window Collaborative

Energy Technology Data Exchange (ETDEWEB)

Eto, J.; Arasteh, D.; Selkowitz, S.

1998-08-01

Market adoption of recent, commercially available technological advances that improve the energy performance of windows will lead to immediate economic and energy savings benefits to the nation. This paper is a scoping study intended to inform the design of a major DOE initiative to accelerate market adoption of these windows in the residential sector. We describe the structure of the US residential window market and the interests of the various market players. We then briefly review five recent market transformation initiatives. Finally, we summarize our findings in a list of considerations we believe will be important for the DOE's initiative to transform the US residential window market.

Innovations in Post-Marketing Safety Research

NARCIS (Netherlands)

Stefánsdóttir, G.

2012-01-01

Safety surveillance is important during the entire life cycle of a drug. Pre-marketing trials have been shown to be ineffective in establishing the full safety profile of the drug, mainly due to their relatively small sample size and characteristics of the patients, which are usually younger and

National post-market surveillance assessment of veterinary medicines in Korea during the past decade.

Science.gov (United States)

Kang, JeongWoo; Park, Hae-Chul; Jang, Yang Ho; Hossain, Md Akil; Jeong, Kyunghun; Jeong, Mi Young; Yun, Seon-Jong; Park, Sung-Won; Kim, Dae Gyun; Lee, Kwang-Jick

2017-05-22

Veterinary medicines have been widely used for the prevention and treatment of diseases, growth promotion, and to promote feeding efficacy in livestock. As the veterinary medicine industry has steadily grown, it is crucial to set up a baseline for the quality of medicine as well as the insufficiency or excessiveness of the active ingredients in drug products to ensure the compliance, safety and efficacy of these medicines. Thus, the 10 years data of post-marketing quality control study was summarized to determine the rate and extent of non-compliance of these medicines and to establish baseline data for future quality control measures of veterinary medicine. In this study, 1650 drugs for veterinary use were collected per year from each city and province in Korea and analysed for the quantity of active ingredients according to the "national post-market surveillance (NPMS) system" over the past decade. The NPMS assessment was performed using liquid and gas chromatography, titration, UV/Vis spectrophotometry, and bioassays. A total of 358 cases were deemed noncompliant, with the average noncompliance rate for all medicine types being 2.0%. The average noncompliance rates for antibiotics, biologics and other chemical drugs except antibiotics (OCD) were 1.1%, 1.2%, and 3.0%, respectively. The first leading cause for noncompliant products was insufficient quantity of major ingredients (283 cases), and the second leading cause was the existence of excess amount of active ingredients (60 cases). Tylosin, spiramycin, ampicillin, tetracyclines and penicillins were most frequently found to be noncompliant among antibiotics. Among the OCD, the noncompliance was found commonly in vitamin A. The overall trend presented gradually decreasing violation rates, suggesting that the quality of veterinary medicines has improved. Consistent application of the NPMS assessment and the establishment of the Korea Veterinary Good Manufacturing Practice (KVGMP) will help to maintain the good

Beyond Design: The Importance of Construction and Post-Construction Phases in Green Developments

Directory of Open Access Journals (Sweden)

Mark Hostetler

2010-04-01

Full Text Available Green developments are becoming a popular land use planning concept that attempts to accommodate growth while minimizing impacts on natural resources. Various policies encourage conservation designs that usually translate into the clustering of homes and the conservation of some percentage of open space. However, the success of a design is determined by what happens during the construction and post-construction phases of a subdivision project. These two phases are often ignored in land use planning and given only minimal attention by built environment professionals. As a result, green developments may not be functioning as originally intended. This essay discusses the importance of construction and post-construction and a way forward to create functional, sustainable communities. Construction activities and decisions, such as impacts from earthwork machines, improper protection of conserved open spaces and trees, the choice of plants used for yards and common areas, and the storage of construction material all can lead to severe impacts on natural areas both within and surrounding a development site. During post-construction, a variety of improper management practices by homeowners can compromise the sustainability of a development. Developers and associated environmental consultant teams could implement approaches that would engage contractors and residents, such as environmental construction covenants and the installment of a neighborhood, environmental education program. To increase the adoption of relevant construction and post-construction practices, appropriate policies need to be created. However, the shift will only occur once the planning and built environment community acknowledges that design is only the first step towards sustainability. Academic design studios and continuing education courses can help with this culture shift by including construction and post-construction considerations within their curriculum.

The development of market power in the Spanish power generation sector: Perspectives after market liberalization

International Nuclear Information System (INIS)

Ciarreta, Aitor; Nasirov, Shahriyar; Silva, Carlos

2016-01-01

This paper provides a comprehensive analysis of the market power problem in the Spanish power generation sector and examines how and to which extent the market has developed in terms of market power concerns after the market liberalization reforms. The methodology applied in this study includes typical ex-post structural and behavioral measures employed to estimate potential for market power, namely: concentration ratios (CR) (for the largest and the three largest suppliers), the Herfindahl–Hirschman Index (HHI), Entropy, Pivotal Supply Index, the Residual Supply Index and Residual Demand Elasticity (RDE). The results are presented for the two largest Spanish generating companies (Endesa and Iberdrola) acting in the Iberian Electricity Market (MIBEL), and in the Spanish Day-ahead electricity market. The results show evidence that these companies have behaved much more competitively in recent periods than in the beginning of the market liberalization. In addition, the paper discusses important structural and regulatory changes through market liberalization processes in the Spanish Day-ahead electricity market. - Highlights: •Competition and regulation in the Spanish electricity market. •The methodology applied in this study: ex-post structural and behavioral measures. •Key dominant companies behaved more competitively in recent periods. •Important structural and regulatory changes in the Spanish electricity market.

Vocations: The Link between Post-Compulsory Education and the Labour Market. What the Research Says For... Tertiary Education Providers & School Educators

Science.gov (United States)

Wheelahan, Leesa; Buchanan, John; Yu, Serena

2015-01-01

This summary brings together the relevant key findings for tertiary education providers and school educators from the research program "Vocations: The Link between Post-Compulsory Education and the Labour Market." The program was comprised of three different strands: (1) pathways from VET in Schools, (2) pathways within and between…

Progress on mobility and instability of research personnel in Japan: scientometrics on a job-posting database for monitoring the academic job market

Energy Technology Data Exchange (ETDEWEB)

Kawashima, H.; Yamashita, Y.

2016-07-01

This study has two purposes. The first purpose is to extract statistics from a database of jobposting cards, previously little-used as a data source, to assess the academic job market. The second purpose is to connect statistics on the academic job market with monitoring of indicators of policy progress related to the mobility and instability of research personnel. The data source used in this study is a job-posting database named JREC-IN Portal, which is the de facto standard for academic job seeking in Japan. The present results show a growing proportion of fixed-term researchers in the Japanese academic job market and that job information is increasingly diverse. (Author)

Safety and Effectiveness of Mirabegron in Patients with Overactive Bladder Aged ≥75 Years: Analysis of a Japanese Post-Marketing Study.

Science.gov (United States)

Yoshida, Masaki; Nozawa, Yumiko; Kato, Daisuke; Tabuchi, Hiromi; Kuroishi, Kentarou

2017-09-12

A 12-week post-marketing study was conducted to provide real-world data on Japanese patients with overactive bladder (OAB) initiating treatment with mirabegron. This post-hoc analysis focused on safety and effectiveness of mirabegron in patients aged ≥75 versus Similar changes were observed for I-PSS QoL in both groups. In a real-world clinical setting, mirabegron was well-tolerated and effective in patients aged ≥75 and <75 years. © 2017 John Wiley & Sons Australia, Ltd.

Using tobacco-industry marketing research to design more effective tobacco-control campaigns.

Science.gov (United States)

Ling, Pamela M; Glantz, Stanton A

2002-06-12

To improve tobacco-control efforts by applying tobacco-industry marketing research and strategies to clinical and public health smoking interventions, we analyzed previously secret tobacco-industry marketing documents. In contrast to public health, the tobacco industry divides markets and defines targets according to consumer attitudes, aspirations, activities, and lifestyles. Tobacco marketing targets smokers of all ages; young adults are particularly important. During the 1980s, cost affected increasing numbers of young and older smokers. During the 1990s, eroding social acceptability of smoking emerged as a major threat, largely from increasing awareness of the dangers of secondhand smoke among nonsmokers and smokers. Physicians and public health professionals should use tobacco-industry psychographic approaches to design more relevant tobacco-control interventions. Efforts to counter tobacco marketing campaigns should include people of all ages, particularly young adults, rather than concentrating on teens and young children. Many young smokers are cost sensitive. Tobacco-control messages emphasizing the dangers of secondhand smoke to smokers and nonsmokers undermine the social acceptability of smoking.

Contemporary Welfare Regimes in Baltic States: Adapting Post-Communist Conditions to Post-Modern Challenges

Directory of Open Access Journals (Sweden)

Anu Toots

2010-11-01

Full Text Available This article revises the conventional approach to welfare state development in the post-communist world, according to which the main challenge for the Eastern European states is to catch up with Western European welfare regimes. The article argues that adjustment to the new social risks and volatile markets is more important today than the catching-up scenario. Based on social and labour market statistics for Estonia, Latvia and Lithuania, the article analyses how the Baltic States are coping with this adjustment challenge. Adaptation to the post-modern conditions can be regarded as successful if the stability of welfare spending is accompanied by the expanding and flexible employment and by the stable or decreasing level of poverty. The findings suggest that the opportunities to increase the flexibility and equality of the labour market provided by the breakdown of the communist regime were not used. Instead, the Baltic welfare states continue to focus on protecting against the old social risks by combining neoliberal and post-communist principles. Poor performance in meeting new social risks poses a greater challenge for the post-communist welfare states than their lag in terms of gross welfare expenditure.

Bubbles, Post-Crash Dynamics, and the Housing Market

OpenAIRE

Crocker H. Liu; Adam Nowak; Stuart Rosenthal

2014-01-01

This paper documents and explains previously unrecognized post-crash dynamics following the collapse of a housing bubble. A simple model predicts that speculative developers ensure stable pre-crash relative prices between small and large homes while their post-crash exit allows small-home relative values to fall. Evidence from Phoenix supports the model. Although home prices doubled 2004-2006, relative prices of small-to-large homes remained nearly constant but then plummeted post-crash. As s...

Sustainable packaging design for consumer electronics products: Balancing marketing, logistics and environmental requirements

OpenAIRE

Wever, R.; Boks, C.B.; Pratama, I.; Stevels, A.L.N.

2007-01-01

Packaging design for consumer electronic products is a challenge because contradictory demands from a distribution perspective and a marketing perspective have to be balanced. With several company departments involved and powerful external stakeholders this is a complicated matter. As the level of sophistication of data concerning a packagings marketing performance is limited, decisions are often strongly based on beliefs. This is reflected in inconsistencies in packaging that is currently in...

Fashion designers on the Czech market

OpenAIRE

Hinková, Barbora

2014-01-01

This Master's Thesis deals with the Czech fashion scene. Development of fashion is outlined in the introduction. It should help to understand the whole market. The work deals with marketing of fashion brands and focuses primarily on marketing Czech fashion brands offering fashions for women. Czech fashion scene is analyzed in detail and pointed out the weaknesses that need to be improved. In connection with the findings outlined here is a solution that should help Czech fashion scene.

Plagiarism issues in post-1998 Indonesian film posters

Directory of Open Access Journals (Sweden)

Ekky Imanjaya

2012-04-01

Full Text Available There are online articles, with visual materials, stating that some post-1998 Indonesian film posters were accused as plagiarism by common people. However, academically speaking, it needs deeper skills and knowledge to prove acts of plagiarism. This paper will discuss the issues around Indonesian film posters and plagiarism, including the possibility of citing in graphic design. The research will treat film posters not only as marketing tools to promote the movies, as many people consider, but also as graphic design materials. Some terms such as appropriation, homage, and pastiche will be discussed to analyze the phenomenon.

What is the optimum social marketing mix to market energy conservation behaviour: an empirical study.

Science.gov (United States)

Sheau-Ting, Low; Mohammed, Abdul Hakim; Weng-Wai, Choong

2013-12-15

This study attempts to identify the optimum social marketing mix for marketing energy conservation behaviour to students in Malaysian universities. A total of 2000 students from 5 major Malaysian universities were invited to provide their preferred social marketing mix. A choice-based conjoint analysis identified a mix of five social marketing attributes to promote energy conservation behaviour; the mix is comprised of the attributes of Product, Price, Place, Promotion, and Post-purchase Maintenance. Each attribute of the mix is associated with a list of strategies. The Product and Post-purchase Maintenance attributes were identified by students as the highest priority attributes in the social marketing mix for energy conservation behaviour marketing, with shares of 27.12% and 27.02%, respectively. The least preferred attribute in the mix is Promotion, with a share of 11.59%. This study proposes an optimal social marketing mix to university management when making decisions about marketing energy conservation behaviour to students, who are the primary energy consumers in the campus. Additionally, this study will assist university management to efficiently allocate scarce resources in fulfilling its social responsibility and to overcome marketing shortcomings by selecting the right marketing mix. Copyright © 2013 Elsevier Ltd. All rights reserved.

The next generation of CANDU: reactor design to meet future energy markets

International Nuclear Information System (INIS)

Hopwood, J.M.; Love, J.W.; Wren, D.J.

2001-01-01

Nuclear power plant designs for the future must respond to increasingly demanding market requirements. This means that value can be gained from substantial product development directed at these requirements. For the CANDU system, AECL has adopted the revolutionary approach, accommodating significant changes to design while retaining traditional CANDU strengths. The focus of the new design is to achieve a 40% reduction in capital cost, quicken construction time and higher efficiency. Key aspects of the new design include: light water coolant, smaller core, slightly enriched fuel, higher temperature and pressure coolant. Work is well advanced on the preliminary design

Are All Marketers Liars ?

OpenAIRE

Sunanto, Sandra

2006-01-01

Today, consumers demand higher levels of quality, reliability, and durability of product A marketer must understand consumer's expectations and try to satisfy those and retain the consumer's loyalty.The shift from golden age of marketing to post age creates new challenge for marketer because consumers do not trust television commercials anymore. In this age consumers love being told a storyTo tell a story marketer must understand what is a great story. A great story must true, authentic, trus...

Post-cam mechanics and tibiofemoral kinematics: a dynamic in vitro analysis of eight posterior-stabilized total knee designs.

Science.gov (United States)

Arnout, N; Vanlommel, L; Vanlommel, J; Luyckx, J P; Labey, L; Innocenti, B; Victor, J; Bellemans, J

2015-11-01

Posterior cruciate ligament (PCL)-substituting total knee arthroplasty (TKA) designs were introduced to avoid paradoxical roll forward of the femur and to optimize knee kinematics. The aim of this in vitro study was to investigate post-cam function and contact mechanics and relate it to knee kinematics during squatting in eight contemporary posterior-stabilized TKA designs. All prostheses were fixed on custom-designed metal fixtures and mounted in a knee rig and five sequential-loaded squats were performed between 30° and 130° of flexion. Contact pressure and contact area were measured using pressure-sensitive Tekscan sensors on the posterior face of the post. Kinematics was recorded with reflective markers and infrared light-capturing cameras. The post-cam mechanisms analyzed in this study are very variable in terms of design features. This leads to large variations in terms of the flexion angle at which the post and cam engage maximal contact force, contact pressure and contact area. We found that more functional post-cam mechanisms, which engage at lower flexion angle and have a similar behavior as normal PCL function, generally show more normal rollback and tibial rotation at the expense of higher contact forces and pressures. All designs show high contact forces. A positive correlation was found between contact force and initial contact angle. Post-cam contact mechanics and kinematics were documented in a standardized setting. Post-cam contact mechanics are correlated with post-cam function. Outcomes of this study can help to develop more functional designs in future. Nevertheless, a compromise will always be made between functional requirements and risk of failure. We assume that more normal knee kinematics leads to more patient satisfaction because of better mobility. Understanding of the post-cam mechanism, and knowing how this system really works, is maybe the clue in further development of new total knee designs.

Design of a decontamination section of the post-irradiation examination laboratory

International Nuclear Information System (INIS)

Homberger, Victor; Coronel, Ruben R.; Laumann, Victor; Perez, Jorge O.; Quinteros, Andrea N.; Ratner, Marcos

1999-01-01

The Post-Irradiation Examination Laboratory activities include the decontamination of expensive equipment of different sizes and weight, involving the complexity and extension of the necessary decontamination. A decontamination section has been designed for that purpose. (author)

Bottom-up design of a gas futures market in East Asia: Lessons from the Dojima rice exchange

Directory of Open Access Journals (Sweden)

Xunpeng Shi

2016-10-01

Full Text Available The natural gas market in East Asia remains fragmented without a functioning benchmark price to duly reflect the dynamics of demand and supply forces in the region. A functional regional gas futures market, which is highly dependent on the presence of well-developed physical spot trading, is yet to be established. Since the intra-regional pipeline connection is largely non-existent in East Asia, it is the LNG spot cargo trading that is likely to become the basis for the regional gas futures market. This paper offers a novel approach to understanding the development of such a market by analyzing the experience of a different commodity market – the Dojima Rice Exchange (DRE – and identifying potentially transferrable lessons in the market design and the role of government regulations. Based on the case study analysis, implications for the development of natural gas trading hubs in East Asia are offered and an LNG futures exchange design is put forward.

Evaluating direct energy savings and market transformation effects: A decade of technical design assistance in the northwestern USA

International Nuclear Information System (INIS)

Van Den Wymelenberg, Kevin; Brown, G.Z.; Burpee, Heather; Djunaedy, Ery; Gladics, Gunnar; Kline, Jeff; Loveland, Joel; Meek, Christopher; Thimmanna, Harshana

2013-01-01

This paper documents the direct energy savings and energy efficiency market transformation impacts of a multi-state design assistance program in the northwestern US. The paper addresses four specific aims. (1) It provides a conservative and justified estimate of the direct energy savings associated with design assistance activities of a market transformation program from 2001 to 2010. (2) It provides a rigorous methodology to evaluate direct energy savings associated with design assistance market transformation programs. (3) It provides a low-cost replicable method to predict energy savings in new buildings by evaluating the integrated design process. (4) It provides quantitative indicators useful for estimating indirect energy savings from market transformation. Applying the recommended analysis method and assuming a 12-year measure life, the direct energy savings of the population (626 buildings; 51,262,000 ft 2 ) is estimated as 45.3 aMW (average megawatts) (electric), and 265,738.089 therms (non-electric). If the entire program budget were divided into the electric savings only, the Lab Network cost per kWh saved ranged from $0.0016 to $0.003 using the recommended method and $0.0092/kWh using the most conservative method. These figures do not isolate contextual influences or represent total resource cost. Statistically significant correlations (r 2 =0.1−0.3) between integrated design scores and energy savings are reported. - Highlights: ► Estimated direct energy savings of a market transformation program are presented. ► A methodology to evaluate energy savings from multiple baselines is documented. ► Level of integrated design can be used to estimate energy savings in new buildings. ► Quantitative evaluation indicators of efficiency market transformation are provided. ► Electric energy saved from design assistance costs between $0.0016 and $0.0092/kWh.

Exposure to digital marketing enhances young adults? interest in energy drinks: An exploratory investigation

OpenAIRE

Buchanan, Limin; Kelly, Bridget; Yeatman, Heather

2017-01-01

Young adults experience faster weight gain and consume more unhealthy food than any other age groups. The impact of online food marketing on "digital native" young adults is unclear. This study examined the effects of online marketing on young adults' consumption behaviours, using energy drinks as a case example. The elaboration likelihood model of persuasion was used as the theoretical basis. A pre-test post-test experimental research design was adopted using mixed-methods. Participants (age...

The German electricity market. Does the present market design provide security of supply?; Strommarkt in Deutschland. Gewaehrleistet das derzeitige Marktdesign Versorgungssicherheit?

Energy Technology Data Exchange (ETDEWEB)

Janssen, Matthias; Peichert, Patrick; Perner, Jens; Riechmann, Christoph [Frontier Economics, Koeln (Germany); Niedrig, Thomas [Formaet Services GmbH, Rheinbach (Germany)

2014-09-15

A heated discussion is being waged in Germany and large parts of Europe over the introduction of what are referred to as capacity mechanisms, whose purpose is to provide security of supply in the electricity sector. In this context two consulting firms have undertaken a both qualitative and quantitative study of the fitness of the present market design, which is based on the ''Energy-Only Market'' (EOM), to provide security of supply in the German electricity market. The authors come to the conclusion that, if suitably framed, the EOM can continue to provide a secure electricity supply in accordance with consumer preferences and at the lowest possible cost.

The specific features of marketing channel design

OpenAIRE

Gudonavičienė, Rasa; Alijošienė, Rasa

2008-01-01

[…] Distribution as one of four elements of marketing complex is inseparable part of marketing decisions, which involves all the decisions about distribution of products to the end user. […] Every enterprise that acts at the conditions of market economy pays a big attention to organization and optimisation of the process of product distribution to the end user. The production performance, success of sales programme and position of the enterprise in the target market depends on product realiza...

Applying intercultural markers obtained from cooking in the design process

NARCIS (Netherlands)

Bruns, M.; Tomico Plasencia, O.; Kint, J.M.L.; Zampollo, F.; Smith, C.

2012-01-01

In post-modern society industrial design has lost many of its cultural values as products are directed to a global market and everybody can understand and use them in the same way. In contrast to the globalization of design, cooking is an activity that is very much embedded in culture. Cooking

LICENCE, DESIGN AND MARKETING EXPERIENCE RELATING TO A PRODUCT OR PROCESS

Directory of Open Access Journals (Sweden)

LIVIU NEAMŢU

2013-08-01

Full Text Available Contracting a licence is buying or selling contract of technology, design and marketing experiencerelating to a product or process, and involves the contracting of knowledge and know-how. The granting of aninternational licence takes place when a company provides, in return for a fee or royalties, technology needed byanother firm to run business operations on a foreign market. When in this form, the granting of the licencerequires at least one of the following items: a brand name; operating experience; manufacturing technology;access to patents and trade secrets/industrial. Company that grants the licence get access on a foreign marketwith very low investment and, in many cases, the benefits of investment and market knowledge of a competentlocal firms. The company that received the licence get access to foreign technology, with a very smallinvestment. There are several very obvious advantages of activity under the license on international markets.The granting of a licence can improve cash flow situation for the company that attaches. Because the license ontechnology allows companies to bring products to market faster, the company enjoys early advantage of apositive balance of cash flow. In addition, obtaining a license means lower development costs. The licensedactivity may mean fewer profits in the long run. Immediate benefits of easy access to new technology, lower costsand the development of an early cash flow are attractive advantages of contracting a licence.

Capacity Markets and Market Stability

International Nuclear Information System (INIS)

Stauffer, Hoff

2006-01-01

The good news is that market stability can be achieved through a combination of longer-term contracts, auctions for far enough in the future to permit new entry, a capacity management system, and a demand curve. The bad news is that if and when stable capacity markets are designed, the markets may seem to be relatively close to where we started - with integrated resource planning. Market ideologues will find this anathema. (author)

Integrating Quality Matters into Hybrid Course Design: A Principles of Marketing Case Study

Science.gov (United States)

Young, Mark R.

2014-01-01

Previous research supports the idea that the success of hybrid or online delivery modes is more a function of course design than delivery media. This article describes a case study of a hybrid Principles of Marketing course that implemented a comprehensive redesign based on design principles espoused by the Quality Matters Program, a center for…

[The role of drug registries in the post-marketing surveillance].

Science.gov (United States)

Traversa, Giuseppe; Sagliocca, Luciano; Magrini, Nicola; Venegoni, Mauro

2013-06-01

The aim of this article is to provide an introduction to issue of Recenti Progressi in Medicina, devoted to the role of drug registries in the post-marketing surveillance. We first motivate the need to implement registries as a tool in promoting the appropriateness of drug use and acquiring additional information on the risk-benefit profile of drugs. Then, the different role that can be played by registries in comparison with prescription monitoring systems and observational studies is clarified. The presentation of some of the most relevant registries established in Italy since the end of the '90s, with the analysis of their strengths and weaknesses, helps to understand some of the crucial issues that should be taken into account before a new registry is adopted. Specifically, we deal with the relationship between objectives - of appropriateness, effectiveness and safety - and methods; the overlapping between drug-based registries and disease-based ones; the duration and extension of data collection, which may be either exhaustive or based on a sampling frame; the importance of ensuring the quality of the data and to minimize the number of subjects who are lost to follow-up; the importance of infrastructures, and of ad hoc funding, for the functioning of a registry; the independence in data analysis and publication of findings.

The market for green building in developed Asian cities. The perspectives of building designers

International Nuclear Information System (INIS)

Chan, Edwin H.W.; Qian, Queena K.; Lam, Patrick T.I.

2009-01-01

Green building (GB) is part of the concept of promoting sustainability. Although GB and the concept of sustainability are well studied for environmental concerns, their business rationale and related social concerns have not been fully explored or widely accepted by the parties involved in the building sector. In this study, the situation of GB market in relation to the general building market is reviewed and the business rationales of stakeholders to invest in the GB market have been investigated from the perspective of building designers. In addition, the factors that enhance the popularity of GB have been explored and the obstacles that hinder its market have been examined. The data are collected by a questionnaire survey covering building designers in Hong Kong and Singapore, the cities that are categorized as economically developed cities in Asia. After data analysis of the survey, this paper presents the findings of the business reasons for stakeholders to be involved in GB, the most favorable conditions required to promote GB business and the important obstacles that hinder its popularity. Based on the findings, recommendations and policy implications are tendered. (author)

Junk Food Marketing on Instagram: Content Analysis.

Science.gov (United States)

Vassallo, Amy Jo; Kelly, Bridget; Zhang, Lelin; Wang, Zhiyong; Young, Sarah; Freeman, Becky

2018-06-05

Omnipresent marketing of processed foods is a key driver of dietary choices and brand loyalty. Market data indicate a shift in food marketing expenditures to digital media, including social media. These platforms have greater potential to influence young people, given their unique peer-to-peer transmission and youths' susceptibility to social pressures. The aim of this study was to investigate the frequency of images and videos posted by the most popular, energy-dense, nutrient-poor food and beverage brands on Instagram and the marketing strategies used in these images, including any healthy choice claims. A content analysis of 15 accounts was conducted, using 12 months of Instagram posts from March 15, 2015, to March 15, 2016. A pre-established hierarchical coding guide was used to identify the primary marketing strategy of each post. Each brand used 6 to 11 different marketing strategies in their Instagram accounts; however, they often adhered to an overall theme such as athleticism or relatable consumers. There was a high level of branding, although not necessarily product information on all accounts, and there were very few health claims. Brands are using social media platforms such as Instagram to market their products to a growing number of consumers, using a high frequency of targeted and curated posts that manipulate consumer emotions rather than present information about their products. Policy action is needed that better reflects the current media environment. Public health bodies also need to engage with emerging media platforms and develop compelling social counter-marketing campaigns. ©Amy Jo Vassallo, Bridget Kelly, Lelin Zhang, Zhiyong Wang, Sarah Young, Becky Freeman. Originally published in JMIR Public Health and Surveillance (http://publichealth.jmir.org), 05.06.2018.

Evaluation of Electronic Healthcare Databases for Post-Marketing Drug Safety Surveillance and Pharmacoepidemiology in China.

Science.gov (United States)

Yang, Yu; Zhou, Xiaofeng; Gao, Shuangqing; Lin, Hongbo; Xie, Yanming; Feng, Yuji; Huang, Kui; Zhan, Siyan

2018-01-01

Electronic healthcare databases (EHDs) are used increasingly for post-marketing drug safety surveillance and pharmacoepidemiology in Europe and North America. However, few studies have examined the potential of these data sources in China. Three major types of EHDs in China (i.e., a regional community-based database, a national claims database, and an electronic medical records [EMR] database) were selected for evaluation. Forty core variables were derived based on the US Mini-Sentinel (MS) Common Data Model (CDM) as well as the data features in China that would be desirable to support drug safety surveillance. An email survey of these core variables and eight general questions as well as follow-up inquiries on additional variables was conducted. These 40 core variables across the three EHDs and all variables in each EHD along with those in the US MS CDM and Observational Medical Outcomes Partnership (OMOP) CDM were compared for availability and labeled based on specific standards. All of the EHDs' custodians confirmed their willingness to share their databases with academic institutions after appropriate approval was obtained. The regional community-based database contained 1.19 million people in 2015 with 85% of core variables. Resampled annually nationwide, the national claims database included 5.4 million people in 2014 with 55% of core variables, and the EMR database included 3 million inpatients from 60 hospitals in 2015 with 80% of core variables. Compared with MS CDM or OMOP CDM, the proportion of variables across the three EHDs available or able to be transformed/derived from the original sources are 24-83% or 45-73%, respectively. These EHDs provide potential value to post-marketing drug safety surveillance and pharmacoepidemiology in China. Future research is warranted to assess the quality and completeness of these EHDs or additional data sources in China.

Designing incentive market mechanisms for improving restructured power system reliabilities

DEFF Research Database (Denmark)

Ding, Yi; Østergaard, Jacob; Wu, Qiuwei

2011-01-01

state. The reliability management of producers usually cannot be directly controlled by the system operators in a restructured power system. Producers may have no motivation to improve their reliabilities, which can result in serious system unreliability issues in the new environment. Incentive market...... mechanisms for improving the restructured power system reliabilities have been designed in this paper. In the proposed incentive mechanisms, penalty will be implemented on a producer if the failures of its generator(s) result in the variation of electricity prices. Incentive market mechanisms can motivate......In a restructured power system, the monopoly generation utility is replaced by different electricity producers. There exists extreme price volatility caused by random failures by generation or/and transmission systems. In these cases, producers' profits can be much higher than those in the normal...

Electric market models, competitive model and alternative design

International Nuclear Information System (INIS)

Arnedillo, O.

2007-01-01

Almost ten years after the liberalization of the Spanish electric system, its market design has remained basically unchanged. Therefore, it is reasonable to consider whether the current model continues to be adequate or whether it should be changed. However, although the current model is far from the absolute optimum, it is suited to the current state of the Spanish system. Only some improvements, such as the reform of the capacity guarantee payment can be undertaken immediately. It will only be possible to undertake other improvements as distribution companies cover all of their electricity needs in forward contracts acquired through a competitive process. (Author)

European Medicines Agency Perspective on Oncology Study Design for Marketing Authorization and Beyond.

Science.gov (United States)

Jonsson, B; Martinalbo, J; Pignatti, F

2017-05-01

In the development of highly active anticancer drugs, the European situation may be viewed as paradoxical. Limited data may support marketing authorization, but may be insufficient for the health economic appraisal needed for reimbursement and market uptake. To achieve this, conventional confirmatory studies may be needed. For products of special interest, studies aimed at optimizing cost-effectiveness may be warranted. Efficient designs of studies to meet these objectives constitute challenges to all stakeholders. © 2017 ASCPT.

Economic market design and planning for electric power systems

CERN Document Server

Mili, Lamine

2010-01-01

Discover cutting-edge developments in electric power systems. Stemming from cutting-edge research and education activities in the field of electric power systems, this book brings together the knowledge of a panel of experts in economics, the social sciences, and electric power systems. In ten concise and comprehensible chapters, the book provides unprecedented coverage of the operation, control, planning, and design of electric power systems. It also discusses:. A framework for interdisciplinary research and education;. Modeling electricity markets;. Alternative economic criteria and proactiv.

Differences in regulation and efficiency on the electricity market. A preliminary study in the Market Design program

International Nuclear Information System (INIS)

Bergendahl, Goeran; Lindblom, Ted; Olsson, Sven-Olof; Sandoff, Anders

2001-05-01

This paper reports the outcome of a pilot study focusing on corporate governance and mechanism design issues concerning the electricity industry. With respect to the on-going deregulation, enlargement and internationalisation of electricity markets, especial emphasis is put on exploring the importance of the regulatory environment for accomplishing overall market efficiency. Throughout this preliminary study a central assumption has been that the actors on electricity markets are trying to maximise profits under conditions of uncertainty and asymmetric information. This means that transaction costs should be taken into consideration when studying and analysing the efficiency of electricity markets. Accordingly, the theoretical framework of this paper is resting largely on information theories, like 'Transaction Cost Economics', 'Agency Theory', 'Public Choice and Regulation' and 'Information Economics'. The pilot study consists of three parts. The first part is focusing on the development of a relevant theoretical framework. This part is demonstrating important pricing principles and regulatory incentives for accomplishing an efficient electricity market and, thus, a fair competition between electricity actors, i.e. power companies and other traders of electricity. In such a market design we have distinguished three cornerstones: 1. Marginal cost based electricity pricing, both for energy and capacity. 2. Long-range planning of production and transmission expansions. 3. Transparent transmission pricing and open access to all regional and local transmission grids. The following areas are examples of theoretical research issues that are of a particular interest in practice: The production and transmission of electricity is characterised by considerable economies of scale. The financing of new production and transmission capacity is, however, hard to manage with internal funding when electricity prices are based on marginal costs. What methods or (pricing) strategies

Papers of a Canadian Institute conference : Western electricity markets forum : Are you prepared for regulatory restructuring and standard market design?

International Nuclear Information System (INIS)

2003-01-01

This forum on western electricity markets presented the latest information concerning several challenges facing the electricity markets of both Western Canada and the United States. Corporate leaders and industry regulators addressed a number of issues. Among them, the California Independent System Operator presented its views on the Standard Market Design initiative which has the potential to alter the dynamics of power markets in Canada and the United States. The creation of a new International Organization for Standardization (ISO) structure for Alberta's deregulated power markets was discussed by both the Power Pool of Alberta and the Alberta Department of Energy. The outlook for electricity price volatility in the west was examined in a presentation by BP Energy Canada. The prospect for transmission links between Alberta and other western states and provinces was the topic of presentations made by ATCO Electric and AltaLink. The future of the power generation in Alberta was discussed by TransAlta, EPCOR, and ENMAX. In addition, there were two case studies presented from the California Energy Commission and the Independent Electricity Market Operator (IMO) of Ontario concerning the progress made to date on electricity deregulation. A look at lessons to be learned from other jurisdictions was also included. A total of sixteen presentations were made at this forum, of which five have been indexed separately for inclusion in this database. refs., tabs., figs

Adequate intraday market design to enable the integration of wind energy into the European power systems

Energy Technology Data Exchange (ETDEWEB)

Weber, Christoph [University Duisburg-Essen, Chair for Energy Economics and Management Sciences, Universitaetsstrasse 12, 45 117 Essen (Germany)

2010-07-15

This contribution analyses the European electricity markets with respect to their aptitude to absorb large amounts of wind energy. Thereby in a first step the market designs of the major European power markets in France, Germany, Scandinavia, Spain and UK are reviewed, with a particular focus on liquidity in the spot and intraday markets. Then some key features of the short-term adjustments required by wind energy are discussed and the necessity of sufficient liquidity in intraday markets is highlighted. For the example of the German market subsequently the discrepancy between the physical short-term adjustment needs and the traded volumes on the intraday market is analyzed. This leads to an evaluation of proposals for improving the liquidity on the short-term market, including the use of continuous spot trading like in UK or the use of intraday auctions like in Spain. (author)

76 FR 17047 - Authority To Designate Financial Market Utilities as Systemically Important

Science.gov (United States)

2011-03-28

... functioning is integral to the soundness of the financial system and the overall economy. The importance of... Council to apply a transparent and clear communication strategy surrounding all designation decisions. The..., Better Markets, The Clearing House, Debevoise & Plimpton, The Depository Trust & Clearing Corporation...

Post-marketing surveillance of OraQuick whole blood and oral fluid rapid HIV testing.

Science.gov (United States)

Wesolowski, Laura G; MacKellar, Duncan A; Facente, Shelley N; Dowling, Teri; Ethridge, Steven F; Zhu, Julia H; Sullivan, Patrick S

2006-08-01

Post-marketing surveillance was conducted to monitor the performance of the OraQuick Advance rapid HIV-1/2 antibody test (OraQuick) on whole blood and oral fluid. Surveillance of routinely collected data on clients tested with OraQuick in 368 testing sites affiliated with 17 state and city health departments between 11 August 2004 and 30 June 2005. For whole blood and oral fluid, we report the median (range) health department OraQuick specificity and positive predictive value (PPV), and the number of clients with discordant results (e.g. who had a reactive rapid test not confirmed positive by Western blot or indirect immunofluorescence). At one site with lower than expected oral-fluid specificity, we evaluated whether device expiration, manufacturing lot, operator practices, or device-storage or testing-area temperatures were associated with false-positive tests. During the surveillance period, 135 724 whole blood and 26 066 oral fluid rapid tests were conducted. The median health department whole blood OraQuick specificity was 99.98% (range: 99.73-100%) and PPV was 99.24% (range: 66.67-100%); the median oral fluid specificity was 99.89% (range: 99.44-100%) and PPV was 90.00% (range: 50.00-100%). A total of 124 discordant results were reported from 68 (0.05%) whole blood and 56 (0.22%) oral fluid rapid tests. The oral fluid specificity at the site with excess oral fluid false-positive tests was 98.7% (95% confidence interval: 98.18-99.11%). The increase in false-positive tests at that site was not associated with any specific device characteristic, operator procedure or temperature condition. The specificity of OraQuick performed on whole blood and oral fluid during post-marketing surveillance was compatible with the manufacturer's claim within the package insert. However, one site experienced lower than expected oral fluid specificity. Sites that observe that the specificity of OraQuick is lower than the range indicated in the package insert should notify the

Mining association patterns of drug-interactions using post marketing FDA's spontaneous reporting data.

Science.gov (United States)

Ibrahim, Heba; Saad, Amr; Abdo, Amany; Sharaf Eldin, A

2016-04-01

Pharmacovigilance (PhV) is an important clinical activity with strong implications for population health and clinical research. The main goal of PhV is the timely detection of adverse drug events (ADEs) that are novel in their clinical nature, severity and/or frequency. Drug interactions (DI) pose an important problem in the development of new drugs and post marketing PhV that contribute to 6-30% of all unexpected ADEs. Therefore, the early detection of DI is vital. Spontaneous reporting systems (SRS) have served as the core data collection system for post marketing PhV since the 1960s. The main objective of our study was to particularly identify signals of DI from SRS. In addition, we are presenting an optimized tailored mining algorithm called "hybrid Apriori". The proposed algorithm is based on an optimized and modified association rule mining (ARM) approach. A hybrid Apriori algorithm has been applied to the SRS of the United States Food and Drug Administration's (U.S. FDA) adverse events reporting system (FAERS) in order to extract significant association patterns of drug interaction-adverse event (DIAE). We have assessed the resulting DIAEs qualitatively and quantitatively using two different triage features: a three-element taxonomy and three performance metrics. These features were applied on two random samples of 100 interacting and 100 non-interacting DIAE patterns. Additionally, we have employed logistic regression (LR) statistic method to quantify the magnitude and direction of interactions in order to test for confounding by co-medication in unknown interacting DIAE patterns. Hybrid Apriori extracted 2933 interacting DIAE patterns (including 1256 serious ones) and 530 non-interacting DIAE patterns. Referring to the current knowledge using four different reliable resources of DI, the results showed that the proposed method can extract signals of serious interacting DIAEs. Various association patterns could be identified based on the relationships among

The POST trial: initial post-market experience of the Penumbra system: revascularization of large vessel occlusion in acute ischemic stroke in the United States and Europe.

Science.gov (United States)

Tarr, Robert; Hsu, Dan; Kulcsar, Zsolt; Bonvin, Christophe; Rufenacht, Daniel; Alfke, Karsten; Stingele, Robert; Jansen, Olav; Frei, Donald; Bellon, Richard; Madison, Michael; Struffert, Tobias; Dorfler, Arnd; Grunwald, Iris Q; Reith, Wolfgang; Haass, Anton

2010-12-01

The purpose of this study was to assess the initial post-market experience of the device and how it is compared with the Penumbra Pivotal trial used to support the 510k application. A retrospective case review of 157 consecutive patients treated with the Penumbra system at seven international centers was performed. Primary endpoints were revascularization of the target vessel (TIMI score of 2 or 3), good functional outcome as defined by a modified Rankin scale (mRS) score of ≤2 and incidence of procedural serious adverse events. Results were compared with those of the Penumbra pivotal trial. A total of 157 vessels were treated. Mean baseline values at enrollment were: age 65 years, NIHSS score 16. After use of the Penumbra system, 87% of the treated vessels were revascularized to TIMI 2 (54%) or 3 (33%) as compared with 82% reported in the Pivotal trial. Nine procedural serious adverse events were reported in 157 patients (5.7%). All-cause mortality was 20% (32/157), and 41% had a mRS of ≤2 at 90-day follow-up as compared with only 25% in the Pivotal trial. Patients who were successfully revascularized by the Penumbra system had significantly better outcomes than those who were not. Initial post-market experience of the Penumbra system revealed that the revascularization rate and safety profile of the device are comparable to those reported in the Pivotal trial. However, the proportion of patients who had good functional outcome was higher than expected.

Project To Design a Marketing Plan for Promoting Educators' Awareness of and Access to ERIC Products. Proposed Marketing Plan.

Science.gov (United States)

Contemporary Associates, Inc., Washington, DC.

The proposed strategy, which is designed to maximize the effectiveness and minimize the costs of marketing the Information Analysis Products (IAPs) produced by the 16 ERIC Clearinghouses, is based on a study of the concept of centralized versus decentralized ordering of selected ERIC products. The experiment measured four variables--postage,…

Crowdsourcing New Product Design on the Web: An Analysis of Online Designer Platform Service

Directory of Open Access Journals (Sweden)

Xin Dai

2013-01-01

Full Text Available A designer is a core resource in the fashion industry. Successful designers need to be creative and quick to understand the business and wider environment in which they are operating. The Designer Platform Service (DPS, which combines the mechanism of crowdsourcing and group buying on the web, provides a platform for entrant designers to try their abilities in the real market practice. Freelance designers post design samples or sketches of products on the website of DPS, and consumers may preorder the products (each at a fixed price online based on the design information. Once the number of ordering reaches or passes a certain threshold, that is, the minimum production quantity (MPQ, DPS will arrange for production and delivery according to the orders received. This novel service boosts the growth of entrant designers and links designing works with real markets directly. We are interested in how the price and MPQ decisions are made in DPS, with consideration of the entrant designer's objective, decision sequences, and customer demand structures. We develop Stackelberg games to model and derive the equilibrium solutions under individual scenarios. Our findings suggest feasibility of the DPS business model.

The Design of E-Commerce System in the Shrimp Paste Industry using the Method of Structured Analysis and Design Technique (SADT to Increase Marketing

Directory of Open Access Journals (Sweden)

Nurdiansyah Yanuar

2018-01-01

Full Text Available The E-Commerce system in the shrimp paste industry is designed to increase the marketing and branding of Payangan shrimp paste. The shrimp paste produced by KUB (Kelompok Usaha Bersama—Business Group and Poklahsar (Kelompok Pengolah Pemasaran—Marketing Processing Group consisting of a number of joint household industries is yet to meet the sales number set. Shrimp paste has several variants, such as the processed one, the raw one and one in the form of powder which constitute the result of the development of maritime research group of Universitas Jember. The target market of the product is both national and international, especially for the powder shrimp paste which is the recent innovation of the maritime research group. It is considered to be a possibility to increase the sales figures and to decrease the marketing costs by optimizing the use of the internet. In order to do so, a system should be design using Structured Analysis and Design Technique (SADT to build an e-commerce application. It is expected that the E-Commerce application can increase the sales of the shrimp paste and reach a wider number of consumers.

Support schemes and market design in international offshore grids

DEFF Research Database (Denmark)

Schröder, Sascha Thorsten

2013-01-01

International offshore grids can combine the grid connection of offshore wind parks with the possibility for international power trading in the future. This paper investigates the choice of support scheme and power market design in international offshore grids and derives resulting incentives...... support. For a stable investment framework in the near future, a tendering/feed-in tariff may be the best choice. It avoids exposing wind farms to balancing with multiple countries. In the long run, also other support scheme options may be of interest....

Market Mechanism Design for Renewable Energy based on Risk Theory

Science.gov (United States)

Yang, Wu; Bo, Wang; Jichun, Liu; Wenjiao, Zai; Pingliang, Zeng; Haobo, Shi

2018-02-01

Generation trading between renewable energy and thermal power is an efficient market means for transforming supply structure of electric power into sustainable development pattern. But the trading is hampered by the output fluctuations of renewable energy and the cost differences between renewable energy and thermal power at present. In this paper, the external environmental cost (EEC) is defined and the EEC is introduced into the generation cost. At same time, the incentive functions of renewable energy and low-emission thermal power are designed, which are decreasing functions of EEC. On these bases, for the market risks caused by the random variability of EEC, the decision-making model of generation trading between renewable energy and thermal power is constructed according to the risk theory. The feasibility and effectiveness of the proposed model are verified by simulation results.

The Internationalization and Market Competition of Tsai Yueh-Hsun’s Post-Confucian TV Drama and Films in East Asia

OpenAIRE

Jocelyn Yi-Hsuan Lai

2018-01-01

This essay investigates the East Asia-oriented TV and film productions of Taiwanese producer-director Tsai Yueh-hsun. His productions have made wide use of the transnational bankability of Taiwanese TV stars. Set in nationally non-specific urban societies, they are categorized as post-Confucian TV dramas, adopting liberal Western values and presenting problems in the authoritative patriarchal culture of the modern yet Confucian East Asia. They have competed in this market with neo-Confucian K...

Market Power in Power Markets: Evidence from Forward Prices of Electricity

DEFF Research Database (Denmark)

Christensen, Bent Jesper; Jensen, Thomas Elgaard; Mølgaard, Rune

We examine the forward market for electricity for indications of misuse of market power, using a unique data set on OTC price indications posted by Elsam A/S, the dominant producer in Western Denmark, which is one of the price areas under the Nordic power exchange Nord Pool. The Danish Competition...... Council (the regulatory government agency) has ruled that Elsam has used its dominant position to obtain excessive spot prices over a period from July 2003 through December 2006. We show that significant forward premia exist, and that they are related both to spot market volatility and misuse of market...... are consistent across forward premium regressions and structural forward pricing models....

Who Moves the Malaysian Stock Market— the U.S. or Japan?: Empirical Evidence from the Pre-, During, and Post-1997 Asian Financial Crisis

Directory of Open Access Journals (Sweden)

Rosylin Mohd. Yusof

2006-09-01

Full Text Available This paper examines long run co-movements between Malaysian stock market and the two largest stock markets in the world: the U.S. and Japan. By employing time-series analysis, i.e., cointegration, variance decompositions, and impulse response functions, the paper seeks to investigate which market actually leads the Malaysian stock market before, during, and after the 1997 Asian financial crisis periods. The results indicate that there is a co-movement of these markets only in the post crisis period. The Japanese stock market is found to significantly move the Malaysian stock market compared to U.S. stock market for the post-crisis period. At the same time, there seems to be a growing proportion of bilateral trade between Malaysia and Japan during the mentioned period. This finding seems to be consistent with the view that the stronger the bilateral trade ties between two countries, the higher the degree of co-movements (Masih and Masih 1999; Bracker et al. 1999; Pretorius 2002; Ibrahim 2003; Kearney and Lucey 2004. Our finding implies that the opportunities of gaining abnormal profits through investment diversification during the post-crisis period in the Malaysian and Japanese stock markets are diminishing as the markets move towards a greater integration. This further implies that any development in the Japanese economy has to be taken into consideration by the Malaysian government in designing policies pertaining to Malaysian stock market.

Enhanced wood fuel handling: market and design studies

Energy Technology Data Exchange (ETDEWEB)

Landen, R.; Rippengal, R.; Redman, A.N.

1997-09-01

This report examines the potential for the manufacture and sale of novel wood fuel handling systems as a means of addressing users' concerns regarding current capital costs and potential high labour costs of non-automated systems. The report considers fuel handling technology that is basically appropriate for wood-fired heating systems of between c.100kW and c.1MW maximum continuous rating. This report details work done by the project collaborators in order to: (1) assess the current status of wood fuel handling technology; (2) evaluate the market appetite for improved wood fuel handling technology; (3) derive capital costs which are acceptable to customers; (4) review design options; and (5) select one or more design options worthy of further development. The current status of wood fuel handling technology is determined, and some basic modelling to give guidance on acceptable capital costs of 100-1000kW wood fuel handling systems is undertaken. (author)

76 FR 2732 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Designation of Longer...

Science.gov (United States)

2011-01-14

...-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Designation of Longer Period for Commission.... Introduction On June 18, 2010, The NASDAQ Stock Market LLC (``Nasdaq'' or the ``Exchange'') filed with the... change. The Commission may extend the period for issuing an order approving or disapproving the proposed...

The development of Facebook marketing utilizing Content marketing. Case: Pirjon Pakari Oy.

OpenAIRE

Lehtikangas, Pauliina

2015-01-01

The purpose of this thesis was to learn how to improve Pirjon Pakari Oy’s brand visibility and overall visibility on Facebook. This was done by trying to add value to the end customer by producing interesting and engaging posts to Pirjon Pakari Oy’s Facebook page. This case study utilized theory from content marketing in attempts to improve the marketing of “Pirjon” Facebook page and therefore a Facebook content marketing strategy was created for Pirjon Pakari Oy. This strategy was implemente...

Basics of case report form designing in clinical research.

Science.gov (United States)

Bellary, Shantala; Krishnankutty, Binny; Latha, M S

2014-10-01

Case report form (CRF) is a specialized document in clinical research. It should be study protocol driven, robust in content and have material to collect the study specific data. Though paper CRFs are still used largely, use of electronic CRFs (eCRFS) are gaining popularity due to the advantages they offer such as improved data quality, online discrepancy management and faster database lock etc. Main objectives behind CRF development are preserving and maintaining quality and integrity of data. CRF design should be standardized to address the needs of all users such as investigator, site coordinator, study monitor, data entry personnel, medical coder and statistician. Data should be organized in a format that facilitates and simplifies data analysis. Collection of large amount of data will result in wasted resources in collecting and processing it and in many circumstances, will not be utilized for analysis. Apart from that, standard guidelines should be followed while designing the CRF. CRF completion manual should be provided to the site personnel to promote accurate data entry by them. These measures will result in reduced query generations and improved data integrity. It is recommended to establish and maintain a library of templates of standard CRF modules as they are time saving and cost-effective. This article is an attempt to describe the methods of CRF designing in clinical research and discusses the challenges encountered in this process.

Design of the AM600 Turbine-Generator for NPPs in Emerging Markets

Energy Technology Data Exchange (ETDEWEB)

Alexandru, Bogdan; Abdoelatef, M. Gomaa; Field, Robert [KEPCO International Nuclear Graduate School, Ulsan (Korea, Republic of)

2015-10-15

In this paper, preliminary analysis related to: (i) the T/G steam flow path, and (ii) the turbine cycle heat balance is examined. Analysis of global electric markets indicates that the current and near term capacity of electrical grids for many developing countries (e.g., Bangladesh, Kenya, Vietnam, Malaysia) is insufficient to reliably incorporate Nuclear Power Plants (NPPs) with large unit sizes (e.g., >1000 MWe). Thus a modern NPP design with a smaller output (-600 MWe) is of interest. To address conditions for such markets, the 'AM600' Turbine-Generator (T/G) design proposed here represents a 600 MWe design which is robust and supports a simplified steam cycle. The proposed shaftline starts with a determination of the number of flows, followed by a determination of the number of high and low pressure stages, followed by heat balance analysis. The conceptual design for the AM600 T/G offers the following: • a stiff shaftline which can offer robust performance in smaller grids lacking optimal stability relative to grid disturbances and frequency variation, • a simplified approach to T/G fabrication, installation, operation, testing, inspections, and maintenance due to design with a single LPT cylinder while maintaining high thermal efficiency, and • a reduced component count for MSRs, FWHs, and power train pumps and drivers (and associated support system components) resulting in lower capital outlays, simplified operations, and further reducing the maintenance, testing, and inspection burden.

Design of the AM600 Turbine-Generator for NPPs in Emerging Markets

International Nuclear Information System (INIS)

Alexandru, Bogdan; Abdoelatef, M. Gomaa; Field, Robert

2015-01-01

In this paper, preliminary analysis related to: (i) the T/G steam flow path, and (ii) the turbine cycle heat balance is examined. Analysis of global electric markets indicates that the current and near term capacity of electrical grids for many developing countries (e.g., Bangladesh, Kenya, Vietnam, Malaysia) is insufficient to reliably incorporate Nuclear Power Plants (NPPs) with large unit sizes (e.g., >1000 MWe). Thus a modern NPP design with a smaller output (-600 MWe) is of interest. To address conditions for such markets, the 'AM600' Turbine-Generator (T/G) design proposed here represents a 600 MWe design which is robust and supports a simplified steam cycle. The proposed shaftline starts with a determination of the number of flows, followed by a determination of the number of high and low pressure stages, followed by heat balance analysis. The conceptual design for the AM600 T/G offers the following: • a stiff shaftline which can offer robust performance in smaller grids lacking optimal stability relative to grid disturbances and frequency variation, • a simplified approach to T/G fabrication, installation, operation, testing, inspections, and maintenance due to design with a single LPT cylinder while maintaining high thermal efficiency, and • a reduced component count for MSRs, FWHs, and power train pumps and drivers (and associated support system components) resulting in lower capital outlays, simplified operations, and further reducing the maintenance, testing, and inspection burden

Electronic Markets Ontology: ideal architecture for global capital market

Directory of Open Access Journals (Sweden)

Davide Khalil

1998-11-01

Full Text Available When approaching electronic capital market design and microstructure with the focus of analysing and improving existing markets with end-state analysis, it is necessary to name an ideal objective. This serves the purposes of technology evaluation and the development of a standard framework for structural measurement in modeling and language paradigm design. An ideal capital market architecture is presented in this paper that is feasible with current technology based on the end-to-end functionality of existing capital markets including internal requirements of participants. Various architectural and ethical issues are introduced and discussed sketching a framework for further work in quantifying electronic markets.

Game Design Jomblo Keren As a Startup Marketing Product

Directory of Open Access Journals (Sweden)

Celvin Laviano

2018-01-01

ability to be able to take advantage of opportunities with the best. Bill Gates once quoted a word from Don Corleone that we must keep our friend close but our enemies even closer. Because of these competitors we will see various types of opportunities and opportunities that exist. The creation of "Jomblo Keren" game design will look at different types of aspects that can be used to get the right predictions to make the games acceptable by the market. These aspects include themes, games platform, visuals, gameplay, and stories.

Design, construction, and performance of superconducting magnet support posts for the Large Hadron Collider

International Nuclear Information System (INIS)

Blin, M.; Danielsson, H.; Evans, B.; Mathieu, M.

1994-01-01

Different support posts for the Large Hadron Collider (LHC) prototype superconducting magnets have been designed and manufactured. They have been evaluated both mechanically and thermally. The posts are made of a tubular section in composite materials, i.e. glass- or carbon-fibre and epoxy resin, with glued metallic heat intercepts and connections. Mechanical tests have been carried out with both radial and axial loads, before and after cooldown to working temperature. The design considerations and future developments concerning dimensions and other materials are also discussed in this paper. Thermal performance has been evaluated at 1.8 K, 5 K and 80 K in a precision heat leak measuring bench. The measurements have been carried out using calibrated thermal conductances (open-quotes heatmetersclose quotes) and boil-off methods. The measured performances of the posts have been compared with analytical predictions

77 FR 68873 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Designation of Longer...

Science.gov (United States)

2012-11-16

... ``Benchmark Orders'' Under NASDAQ Rule 4751(f) November 9, 2012. On May 1, 2012, The NASDAQ Stock Market LLC...-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Designation of Longer Period for Commission... proposed rule change to establish various ``Benchmark Orders'' under NASDAQ Rule 4751(f). The proposed rule...

Jumpin’ Jacks: Social Marketing Campaign Aimed to Increase Awareness of Healthful Behavior in South Dakota Fourth Grade Students

Directory of Open Access Journals (Sweden)

Megan N. Olesen

2016-06-01

Full Text Available This study investigated the influence of utilizing a collegiate mascot as a marketing tool for the promotion of fruit and vegetable intake and physical activity among 4th grade students. The program utilized service learning and formative research for the development of a social marketing campaign comprised of nutrition education and brand marketing. A pre-test/post-test design was used to measure fruit and vegetable intake and physical activity in participants in intervention and control schools. Awareness and understanding of the campaign was assessed post-intervention. There were no changes in fruit and vegetable intake or physical activity. However, 91% of the intervention students were able to correctly report understanding of the campaign messages, and approximately one-third of the participants were able to recall the campaign without any prompts. Results demonstrated how a social marketing campaign can utilize branding techniques to bring about awareness, which is an essential step in initiating behavior change.

Labour Market Structure in Malaysia: Pre- and Post-Market Gender Comparison

OpenAIRE

Chung-Khain Wye; Rahmah Ismail

2012-01-01

Gender inequality in Malaysian labour market can be observed through labour force participation, unemployment, occupational distribution, top management employment involving decision making, and average monthly salary. Such an inequality generally works to the disadvantage of females, notwithstanding their outperformance of educational attainment over their males’ counterparts. Case study in the ICT services subsector points to the importance of imparting employability skills among females to...

Risk management and post-marketing surveillance of CNS drugs.

Science.gov (United States)

Henningfield, Jack E; Schuster, Charles R

2009-12-01

Drugs affecting the central nervous system span a broad range of chemical entities, dosage forms, indications, and risks. Unintended consequences include potential abuse and overdose in non-patient drug abusers, deliberate tampering of drug dosage forms, and criminal behavior associated with diversion. Regulators must consider diverse factors to find the appropriate conditions of approval to minimize unintended consequences while enabling a level of access desired by health care providers and patients. This commentary appears as part of a special issue of Drug and Alcohol Dependence that focuses on risk management and post-marketing surveillance and addresses key issues that pose real-world challenges to pharmaceutical sponsors and regulators in particular. For example, in the U.S., Controlled Substances Act drug scheduling can be considered a risk management strategy but its legal authorities and administrative processes are independent from those of risk management (including Risk Evaluation and Mitigation Strategies or REMS); better harmonization of these approaches is vital from drug development and regulatory perspectives. Risk management would ideally be implemented on a strong science foundation demonstrating that the tools employed to mitigate risks and ensure safe use are effective. In reality, research and evaluation of tools in this area is in its infancy and will necessarily be an evolutionary process; furthermore, there is little precedent for linking interventions and program evolution to unintended consequences such as regional outbreaks of abuse and diversion. How such issues are resolved has the potential to stimulate or stifle innovations in drug development and advance or imperil health care.

Revisiting support policies for RES-E adulthood: Towards market compatible schemes

International Nuclear Information System (INIS)

Huntington, Samuel C.; Rodilla, Pablo; Herrero, Ignacio; Batlle, Carlos

2017-01-01

The past two decades of growth in renewable energy sources of electricity (RES-E) have been largely driven by out-of-market support policies. These schemes were designed to drive deployment on the basis of specific subsidies sustained in time to allow for the larger costs as well as to limit investor risk. While these policies have proven to be effective, the way they have been designed to date has led to costly market distortions that are becoming more difficult to ignore as penetrations reach unpreceded levels. In the context of this growing concern, we provide a critical analysis of the design elements of RES-E support schemes, focusing on how they affect this trade-off between promoting and efficiently integrating RES-E. The emphasis is on the structure of the incentive payment, which in the end turns to be the cornerstone for an efficient integration. We conclude that, while needed, a well-designed and further developed capacity-based support mechanism complemented with ex-post compensations defined for reference benchmark plants, such as the mechanism currently implemented in Spain, is an alternative with good properties if the major goal is truly market integration. The approach is robust to future developments in technology cost, performance and market penetration of RES-E. - Highlights: • Market distortions due to RES support mechanisms are becoming difficult to ignore. • This paper provides a critical analysis of the design elements of RES support schemes. • The emphasis is on the structure of the incentive, key for an efficient integration. • We argue in favor of a further developed capacity-based support mechanism. • The incentive should be combined with the design of a set of reference plants.

DESIGN FOCUSED ORIENTATION PROCESSES FOR MANAGING INVESTMENT COMPANIES IN THE FOREIGN EXCHANGE MARKET

Directory of Open Access Journals (Sweden)

Анатолий Аркадьевич АНАТОЛЬЕВ

2015-05-01

Full Text Available This report examines the investment companies operating in the market Forex. Business process analysis showed the design direction of their activities. Dedicated two groups of projects of investment companies can position them as project-oriented organization.

Market design : Common Nordic end-user market

Energy Technology Data Exchange (ETDEWEB)

2009-07-01

No later than 2015, suppliers in the Nordic countries should be able to offer electricity to consumers in any Nordic country on equal terms. In this report NordREG has analyzed the present situation in the Nordic countries and identified the issues that should be harmonised in order to establish a common Nordic end-user market. In this report NordREG also suggests an indicative road map for the implementation process. (Author)

Marketing the Library.

Science.gov (United States)

Dragon, Andrea C.

1979-01-01

Describes the positive action using marketing strategies that libraries must take to capture their share of the post-Proposition 13 tax dollar. Strategies discussed relate to price, product, promotion, and place. (JD)

Carbon auctions, energy markets and market power: An experimental analysis

International Nuclear Information System (INIS)

Dormady, Noah C.

2014-01-01

This paper provides an experimental analysis of a simultaneous energy-emissions market under conditions of market power. The experimental design employs real-world institutional features; including stochastic demand, permit banking, inter-temporal (multi-round) dynamics, a tightening cap, and resale. The results suggest that dominant firms can utilize energy-emissions market linkages to simultaneously inflate the price of energy and suppress the price of emissions allowances. Whereas under prior market designs, regulators were concerned with dominant firms exercising their market power over the emissions market to exclude rivals and manipulate the permit market by hoarding permits; the results of this paper suggest that this strategy is less profitable to dominant firms in contemporary auction-based markets than strategic capacity withholding in the energy market and associated demand reduction in the emissions market. - Highlights: • Laboratory simulation of joint energy-emissions market. • Evaluates market power under collusion and real-world institutional features. • Dominant firms can exercise market power to inflate energy prices. • Dominant firms can exercise market power to suppress emissions prices. • Supply withholding is an implicit demand reduction in the emissions market

Misuse of social media marketing by alcohol companies

Directory of Open Access Journals (Sweden)

Zakirhusain A Shaikh

2015-01-01

Full Text Available Background and Aims: Epidemiological transition in the form of noncommunicable diseases (NCDs now becoming the main cause of mortality and morbidity is very much evident even in developing countries like India. Alcohol is an important risk factor for NCD. The use of alcohol is increasing especially in young people and women. This increased use can be attributed to aggressive and innovative marketing by alcohol, in spite of and due to restrictions on its marketing. Social media, in recent times, has been misused by alcohol companies for marketing their products legally, due to legal loophole. The present study examined the reach of alcohol companies on social media and the marketing strategies used by them. Design, Settings, Participants: Facebook, Twitter and YouTube were explored for accounts and content by alcohol companies for marketing their product. Policies of social media sites pertaining to alcohol marketing were also studied. Measurements: Alcohol marketing was measured in terms of content posted by alcohol companies, use of direct or surrogate advertisement and engagement with users. Findings: Alcohol companies have been conveniently using social media to target young urban population with direct and surrogate advertisements of their products. Current social media policies and laws are ineffective in controlling it. Conclusions: Amendment of laws pertaining to alcohol marketing to include social media also in its ambit is necessary. Social media sites should revise their policies to prevent alcohol marketing and promotion especially to underaged users.

Financial Investment Management: Testing the Market Model on the Romanian Capital Market during the Post Financial Crisis

Directory of Open Access Journals (Sweden)

Radu CIOBANU

2011-06-01

Full Text Available This article presents an analysis of the decision of investing in the capital market in Romania during 2009-2010, in the context of overcoming the global financial crisis. In the first part of the paper, we have made a brief presentation of the simplified model of market analysis introduced in the specialized literature by William Sharpe, the respective model representing the starting point in our study. The purpose of the present study is to emphasize how the evolutions of the financial securities rates listed on the Bucharest Stock Exchange could be explained based on the evolution of BET Romanian capital market index. Although the study over this phenomenon has begun in the middle of the last century, every day new studies appear that are either coming in addition to the already existing ones or are bringing a new approach regarding the financial theory. The novelty of the present study conducted by us resides in the highlighting of the evolutions of the financial securities rates during July 2009 – December 2010 periods. The second part of the paper presents the results of a study conducted on the Romanian capital market, emphasizing the correlations between the most important securities on the Romanian capital market, as parts of BET index and market index. The aim is to check whether during this period the evolution of the financial securities’ return can be explained more or less by the return of the capital market.

Tendances Carbone no. 92. Carbon markets and the post-2020 Agreement

International Nuclear Information System (INIS)

Marcu, Andrei

2014-06-01

Among the publications of CDC Climat Research, 'Tendances Carbone' bulletin specifically studies the developments of the European market for CO 2 allowances. Beside some statistical figures about energy production/consumption and carbon markets, this issue specifically addresses the following points: - EU ETS reforms: on 25 June, the EU Commission will host a panel of experts to discuss technical aspects of the proposal of the Market Stability Reserve. - Market Stability Reserve of the EU ETS: Germany supports the Commission proposal of a market stability reserve and calls for a launch of the mechanism significantly before 2020, i.e. already in 2017. - 2030 energy and climate package: on 26 and 27 June, the EU Council will discuss the target of CO 2 emissions reduction of 40% by 2030 to take a final decision as soon as possible and later in October 2014

Fuel cells niche market applications and design studies

Energy Technology Data Exchange (ETDEWEB)

NONE

2000-07-01

Mainstream fuel cell markets such as stationary power and transport propulsion have already received considerable attention. However, the niche areas considered in this report also offer considerable markets that are considered potentially ready for exploitation. This report examines those markets and considers the broad issues for exploitation. This programme of work has been funded under the DTI's Advanced Fuel Cell Programme. The overall aim of this project was to identify and evaluate niche market applications that have the potential to provide early commercially competitive market opportunities for fuel cell systems. Battery replacement, portable, mobile auxiliary power and stationary applications for non-standard generation are covered. (author)

The Marketing Plan: An Integrative Device for Teaching Marketing Management.

Science.gov (United States)

Berdine, W. R.; Petersen, James C.

1980-01-01

The importance of the marketing plan is stressed as an integrative device for teaching marketing management, and a structure is presented to assist students in designing a marketing plan. Components of this plan include marketing objectives, targeting market and buying motives, external environment and competition, product, price, and promotion.…

Sustainable packaging design for consumer electronics products : Balancing marketing, logistics and environmental requirements

NARCIS (Netherlands)

Wever, R.; Boks, C.B.; Pratama, I.; Stevels, A.L.N.

2007-01-01

Packaging design for consumer electronic products is a challenge because contradictory demands from a distribution perspective and a marketing perspective have to be balanced. With several company departments involved and powerful external stakeholders this is a complicated matter. As the level of

Conducting wine marketing research with impact in China: Guidelines for design, execution and dissemination

OpenAIRE

Justin Cohen; Larry Lockshin

2017-01-01

China is the fastest growing wine market, but conducting research there is fraught with a variety of issues. This article explores some of the issues the authors have dealt with in conducting wine marketing research in China over the last five years. We discuss issues with the design of research to focus on important issues for both academics and the industry. We relate the key problems in gaining proper translation and useful sampling procedures. Finally, we provide some guidelines for commu...

Students’ Preferences And Opinions On Design 
Of A Mobile Marketing Education Application

Directory of Open Access Journals (Sweden)

F. Zeynep OZATA

2014-01-01

Full Text Available The purpose of this study was to define and better understand business school students’ opinions and preferences on the design of a mobile marketing education application. To accomplish this purpose an explanatory mixed methods study design was used and the data was collected sequentially. First, a questionnaire was conducted with 168 business school students from Anadolu University to define their learning styles. The learning orientation questionnaire produced five factors: visual, auditory, dependent, collaborative, and reading & writing learning styles. In the second phase of the study, semi-structured in depth interviews were conducted with nine graduate students at Anadolu University to better understand their preferences and explore their opinions on the mobile application. After the coding process three themes emerged: learning styles, content, and tools. Added to these themes, eight motives for the use of a mobile marketing education application were also identified.

THE ANALYSIS AND THE DESIGN OF E-MARKETING STRATEGY AT SME’S (A CASE STUDY: THE DARE TO DREAM INDONESIA COMMUNITY

Directory of Open Access Journals (Sweden)

Henkie Ongowarsito

2011-10-01

Full Text Available The purposes of the research are to analyze the e-marketing strategy and to design e-marketing application which is a website that is appropriate for SME’S of Dare to Dream Indonesia (D2DI community. The methodology of analysis used consists of 4 stages from 7 stages of e-marketing and the design method consists of three last stages of e-marketing. The result achieved is a website as an e-marketing application that can support marketing and promoting activities, expanding the target market, giving complete information and facilitating the customers to access product information, and supporting the communication between D2DI community, SME’S, and the customers. The conclusions obtained are that e-marketing can be a solution to solve customer needs of the availability of complete and current information and communication.Keywords: Information System, content management system, academic development

Liquidity and Impact in Fair Markets

OpenAIRE

Jaisson, Thibault

2015-01-01

We develop a theory which applies to any market dynamics that satisfy a fair market assumption on the nullity of the average profit of simple market making strategies. We show that for any such fair market, there exists a martingale fair price which corresponds to the average liquidation value (at the ask or the bid) of an infinitesimal quantity of stock. We show that this fair price is a natural reference price to compute the ex post gain of limit orders. Using only the fair market assumptio...

An Integrated Design approach to Power Systems: from Power Flows to Electricity Markets

Science.gov (United States)

Bose, Subhonmesh

Power system is at the brink of change. Engineering needs, economic forces and environmental factors are the main drivers of this change. The vision is to build a smart electrical grid and a smarter market mechanism around it to fulfill mandates on clean energy. Looking at engineering and economic issues in isolation is no longer an option today; it needs an integrated design approach. In this thesis, I shall revisit some of the classical questions on the engineering operation of power systems that deals with the nonconvexity of power flow equations. Then I shall explore some issues of the interaction of these power flow equations on the electricity markets to address the fundamental issue of market power in a deregulated market environment. Finally, motivated by the emergence of new storage technologies, I present an interesting result on the investment decision problem of placing storage over a power network. The goal of this study is to demonstrate that modern optimization and game theory can provide unique insights into this complex system. Some of the ideas carry over to applications beyond power systems.

Toward the Target Model 2.0. Policy Recommendations for a Sustainable EU Power Market Design. Executive summary

International Nuclear Information System (INIS)

Roques, Fabien; Perekhodtsev, Dmitri; Verhaeghe, Charles

2015-06-01

One of the 10 key priorities of the new European Commission President Jean-Claude Juncker consists of 'reform(ing) and reorganis(ing) Europe's energy policy into a new European Energy Union'. The Energy Union work programme released on 25 February 2015 suggests that a new electricity market design is needed in order to tackle Europe's chosen policy objectives of de-carbonisation whilst maintaining security of supply. The current regulatory and market framework does not provide a sound basis for the investments needed to maintain security of supply and de-carbonise the power sector at an affordable cost. As policy priorities in favour of de-carbonisation and maintaining security of supply have taken centre stage on the policy agenda in the past decade, the design of liberalised electricity markets has failed to evolve and be reconciled with these new priorities. In addition, the issues of competitiveness and affordability of electricity in Europe remain central in the discussions about the market framework. The objective of this study is to assess the deficiencies and gaps in the current European Target Model and the wider regulatory framework for power generation and to propose a number of policy recommendations for improvement. Recognising the need for 'fresh thinking' on the issue, this study looks outside Europe to learn the lessons from experiences with a range of alternative market designs that exist around the globe. The study provides a comprehensive assessment of the issues with current European electricity markets. The study investigates the lessons from market reforms in North America and in Latin America in the past decade to identify 'out of the box' thinking to fill the gaps in the current European Target model. This report presents some of the research findings and concludes with a set of alternative potential directions for reform of European power markets models in the long term, as well as a number of

Design Capitalism: Design, Economics and Innovation in the Auto-Industrial Age

Directory of Open Access Journals (Sweden)

Peter Murphy

Full Text Available Automation is replacing white-collar office work and non-dexterous manual work, causing major structural change in the job market. As advanced economies shift from a post-industrial to an auto-industrial model, all kinds of routine work is being replaced by machines. Mid-range job opportunities are shrinking, and labor markets are polarizing. Demand for dexterous service work nevertheless remains strong, as does demand for abstract labor working with patterns rather than with rules or procedures. Design is a mid-tier occupation that is growing rather than declining. “Design” is also a metaphor for abstract labor of all kinds; it exemplifies work that is creative, innovative, problem-solving, and reliant on judgment rather than rules. Heightened demand for abstract labor reflects the evolving nature of capitalist economies. The contribution of invention, ingenuity and imagination to the creation of economic value continues to expand. The auto-industrial era is coeval with design capitalism; together they represent a key dimension of future economics.

77 FR 39314 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Designation of a Longer...

Science.gov (United States)

2012-07-02

...-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Designation of a Longer Period for Commission Action on Proposed Rule Change To Establish ``Benchmark Orders'' Under NASDAQ Rule 4751(f) June 26, 2012. On May 1, 2012, The NASDAQ Stock Market LLC (``NASDAQ'' or ``Exchange'') filed with the...

Content Analysis of Assessment Data in Marketing Education

Science.gov (United States)

Vowles, Nicole; Hutto, Alexandra; Miller, Peter Max M.

2017-01-01

This study analyzes a sample of students' writing to assess their understanding of marketing concepts in the context of a Principles of Marketing course. Content analysis of pre- and post-essays was used to assess student knowledge of marketing concepts. The data was collected in Principles of Marketing classes. and highlight that many students…

Relation Between Estimated Cardiorespiratory Fitness and Atrial Fibrillation (from the Reasons for Geographic and Racial Differences in Stroke Study).

Science.gov (United States)

Bose, Abhishek; O'Neal, Wesley T; Bennett, Aleena; Judd, Suzanne E; Qureshi, Waqas T; Sui, Xuemei; Howard, Virginia J; Howard, George; Soliman, Elsayed Z

2017-06-01

Estimated cardiorespiratory fitness (e-CRF) based on readily available clinical and self-reported data is a promising alternative to the costly traditional assessment of CRF using exercise equipment, but its role as a predictor for incident atrial fibrillation (AF) is unclear. This study included 10,126 participants (54.5% women, 35% African-American, mean age 63.2 years) from the Reasons for Geographic and Racial Differences in Stroke study who were free of AF at baseline. Baseline (2003 to 2007) e-CRF was determined using a previously validated nonexercise algorithm. Incident AF cases were identified at a follow-up examination by electrocardiogram and self-reported medical history of previous physician diagnosis. After a median follow-up of 9.4 years, 906 participants (8.9%) developed AF. In a multivariable logistic regression model adjusted for sociodemographics and baseline cardiovascular disease risk factors as well as incident coronary heart disease, heart failure, and stroke, each 1-metabolic equivalent of task increase in e-CRF was associated with a 5% lower risk of AF development (odds ratio [95% CI] 0.95 [0.92 to 0.99]; p = 0.0129). This association was stronger in women (OR [95% CI] 0.85 (0.79, 0.92) than in men (OR (95% CI) 0.88 (0.84, 0.93), interaction p value = 0.05. No significant interactions by age, race, history of cardiovascular disease, or physical limitations were observed. In conclusion, e-CRF using a nonexercise algorithm is a useful predictor of incident AF, which is consistent with previous reports using traditional CRF. This suggests that e-CRF using nonexercise algorithms may serve as a useful alternative to CRF measured by costly and time-consuming exercise testing. Copyright © 2017 Elsevier Inc. All rights reserved.

Supply assurance in the electricity market. Is the investment dilemma the result of inefficient market design?; Versorgungssicherheit auf Elektrizitaetsmaerkten. Investitionsdilemma durch ineffizientes Marktdesign?

Energy Technology Data Exchange (ETDEWEB)

Buedenbender, Martin [Muenster Univ. (Germany). Inst. fuer Genossenschaftswesen; Janssen, Matthias; Wobben, Magnus [Muenster Univ. (Germany). Lehrstuhl Volkswirtschaftstheorie

2009-03-15

This article addresses the investment dilemma in the area of power generation, which in insufficiently designed, liberalized power markets leads macroeconomically to undesirably low levels of energy supply security. The prime causes for this dilemma in the German power market are rooted first in damages for suppliers which are limited in cases of generation capacity-induced power failures and second in the time delay between the final trading opportunity and the actual power delivery. The latter inhibits the ability to individually balance unexpected changes in rates of power generation and discharge at any time. Furthermore, the following factors contribute to an intensification of the dilemma: insufficient end user participation in the wholesale market, a lack of single end user cut-off options, as well as time lags in the construction of generation capacities combined with various market uncertainties. Potential approaches to a sustainable improvement of supply security include on the one hand an increase in liquidity of intraday trading to align market clearing and power delivery as closely as possible. The promotion of direct marketing for renewable energy along with other strategies will lead to such an improvement. On the other hand, end users' utilization of smart meters should be enhanced. Thus, peak load could be moderated and allows for the inclusion of end users' willingness to pay into the wholesale market. (orig.)

State and market in post-reform Brazilian air transportation

Directory of Open Access Journals (Sweden)

Cristiano Fonseca Monteiro

2009-10-01

Full Text Available The changes that have taken place in Brazilian air transportation following the cycle of “market reforms” have turned this sector into an object of growing interest. This interest, in turn, has led to the emergence of a broad literature on the subject, characterized by the emphasis on an agenda of liberalization and the critique of State activism. The goal of the present article is to promote a confrontation between the different interpretations that have been made, incorporating the contributions of approaches inspired in Economic Sociology and in institutionalist analyses in order to draw attention to the importance that political variables, and the State in particular, have for economic performance. The post-reform context is characterized by an initial moment of greater State activism regarding air transportation, through re-initiation of stricter regulatory mechanisms and the re-opening of channels of dialog between state actors and firms. This is followed by a second moment in which state activism is abandoned, at the same time that the sector demonstrates expressive rates of growth, pushing it beyond its existing capacity and flight support infrastructure. This culminated in the episode known as the “apagão aéreo” (aerial black out Analysis of testimonies of state and private sector actors regarding the “blackout” enables us to identify the flaws in the responsible state apparatus as one of the factors that led to the “blackout”. Our conclusions draw attention to the importance of taking political factors into consideration, and particularly the role of the State, in the development of air transportation in Brazil. Keywords: commercial aviation, politics and economics, regulation, Economic Sociology, Historical Institutionalism.

Limits and opportunities of marketeering tertiary education in post-colonial Zimbabwe

OpenAIRE

Patrick Sibanda

2016-01-01

This paper intended to assess the impact of marketeering tertiary education in Zimbabwe. The paper revealed that marketeering of tertiary education in Zimbabwe has drastically impacted on access to higher education and training. Poor and vulnerable students have found it difficult to access tertiary education due to escalating commercialized fees. Literature indicates that, even in developed countries like UK, marketeering tertiary education has led to decreased enrolments, diminishing prospe...

Design considerations for post accident monitoring system of a research reactor

International Nuclear Information System (INIS)

Jang, Gwi Sook; Park, Je Yun; Kim, Young Ki

2012-01-01

The Post Accident Monitoring System (PAMS) provides primary information for operators to assess the plant conditions and perform their role in bringing the plant to a safe condition during an accident. The PAMS of NPP (Nuclear Power Plant) in KOREA provides the continuous display of the PAM category 1 parameters specified in R.G 1.97, Rev. 03. Recently the PAMS of NPP has been designed according to R.G 1.97, Rev. 04. There is no PAMS at the HANARO in KOREA, but recently RRs (Research Reactors) around the world are going to have PAMS for various multi purposes. We should determine the design considerations for PAMS in a Korean RR based on the design state analysis. Thus, this paper proposes strategies on the design considerations for the PAMS of a Korean RR

The microwave market

International Nuclear Information System (INIS)

Bybokas, J.

1989-01-01

As superconductors move from the laboratory to the marketplace, it becomes more important for researchers and manufacturers to understand the markets for this technology. The large market for microwave systems represents a major opportunity for high-T c superconductors. Conductor losses are a primary design limitation in conventional microwave systems. The low losses of superconductors at microwave frequencies will allow component designers and system designers to improve their products in many ways. The most important market segments for microwave systems are outlined in this discussion

Post accident training program design at Three Mile Island

International Nuclear Information System (INIS)

Lawyer, L.L.

1981-01-01

The TMI preaccident training staff typically consisted of 9 professional and 3 administrative support persons. Procedures were prepared and facilities designated for operator training. The thrust of the post accident effort was directed to expanding the training function to include all other personnel while modifying the operator training to address lessons learned. Significant experiences were encountered in part task simulation, job and task analysis, decision analysis and with various external committees. These experiences led to specific opinions on industry needs in the areas of staffing, regulation, importance of training and contractor assistance

"E-tivities from the Front Line”: A Community of Inquiry Case Study Analysis of Educators’ Blog Posts on the Topic of Designing and Delivering Online Learning

Directory of Open Access Journals (Sweden)

Phemie Wright

2014-04-01

Full Text Available Designing and implementing successful online learning has been at the forefront of institutional agendas since digital learning increased in market demand over the last decade. However there is still ongoing debate as to the “how” of this arduous task. The Community of Inquiry (CoI is one learning design method that has seen potential in the field, but practical implementation of designing for the important components of Social, Cognitive and Teaching Presence have yet to be fully realised. This paper researches an e-learning design strategy called E-tivities as a suggested possible method for designing for CoI components. The research explored recent online blog posts of experienced learning designers’ and educators’ experience in designing successful online learning using E-tivities. Results suggest the E-tivities do have the potential to cater for all Presences of CoI. Specifically when using E-tivities to design online learning Affective Expression was the highest reported Social Presence design factor. All four components of Cognitive Presence appeared to be present in E-tivities design. The most important component for adequate Teaching Presence factors was the initial Design and Organisation of the course. E-tivities and the 5-Stage Model provides a solid framework for this to occur.

A post-marketing study of gadodiamide hydrate in patients with cerebral infarction

International Nuclear Information System (INIS)

Ono, Yuko; Aoki, Shigeki

2003-01-01

We evaluated the efficacy and safety of gadodiamide hydrate (GH: Omuniscan) in patients with cerebral infarction in a multicenter post-marketing study. A total of 122 patients enrolled in this study at 16 institutions in throughout Japan. We administrated GH to patients intravenously at 0.2 mL/kg, an approved usage and dosage for head MRI. Efficacy was evaluated by comparing contrast intensity and diagnostic improvement on T1WI before and after the administration of GH and diagnostic significance was investigated. Moreover, clinical data thus obtained were compared with those of phase III studies of GH and other contrast agents with respect to general evaluation of diagnostic improvement. The effects of contrast enhancement on the detection and extent of lesions as well as image quality were judged in terms of improving general evaluation and diagnosis, which was observed in 93.3% of the patients. No serious adverse event were associated with GH administration. The efficacy of GH in this clinical trial was higher, than historical data, with respect to general evaluation and diagnostic improvement. Contrast enhanced MRI with GH in cerebral infarction was confirmed to be of diagnostic value. (author)

From Academic to Post-Academic Science

Directory of Open Access Journals (Sweden)

Mohammad Amin Ghaneirad

2014-03-01

Full Text Available This paper studies the cultural change in science from academic science to post-academic science by the use of documentary studying and analytical reasoning. The aim of this study is determining the direction of cultural change in science and comparing it with cultural change in society.The knowledge production which surrounds academy has little relationship with the values of society and epistemological norms regulate scientists' behavior from within the scientific system. But in post-academic science the relationship between science and society operates in the same line with market and government and science produce within the social context and scientists' behavior controlled by the norms out of the scientific system. So the culture of science has changed because science applied to meet the requirements of market and industry. The result is that contrary to cultural change in society that goes from materialism to post-materialism, cultural change in science moves from post-materialism to materialism.

Incorporating Spirituality and Market: Islamic Sharia Business and Religious Life in Post-New Order Indonesia

Directory of Open Access Journals (Sweden)

Wildan Sena Utama

2016-06-01

Full Text Available 0 0 1 154 880 wildan 7 2 1032 14.0 Normal 0 false false false EN-US JA X-NONE Artikel ini membahas tentang transformasi religious kelas menengah Indonesia danhubungannya dengan pertumbuhan pasar syariah pada pasca-Orde Baru di Indonesia.Artikel ini berpendapat bahwa dalam era neoliberal Indonesia, kebangkitan spiritualini sangat memengaruhi ranah ekonomi. Transformasi kesalehan kelas menengahIndonesia menandai munculnya potensi pasar ekonomi baru. Hal itu direspon secaraantusias oleh pasar dengan memproduksi produk yang selektif berisi konten spiritual.Dalam prosesnya, peran para agen gaya hidup spiritual memainkan peranan pentingdalam membantu dan membentuk kelas menengah urban baru ini dalam mengonsumsiIslam untuk menandakan identitas keislaman mereka. Kemudian muncullah perpaduanaktif antara kesalehan Islam dan kapitalisme dalam situasi Indonesia kontemporer.Konsumsi simbolis Islam menjadi sumber baru dari spiritualisme maupun sumber dariidentifikasi religius. Akan tetapi, artikel ini berpendapat bahwa proses ini cenderungmenyederhanakan Islam sebagai ‘prosesi material’ daripada ‘prosesi spiritual’. This article examines the religious transformation of the Muslim middle class and itsrelationship with the growing sharia market in post-New Order Indonesia. It arguesthat in the Indonesian neo-liberal era, this spiritual revival considerably influenced theeconomic realm. The transformation of piety of the Indonesian middle class markedthe emergence of new potential economic markets. It was responded to enthusiasticallyby markets producing selective products with a spiritual content. In its process, therole of spiritual lifestyle agents played a pivotal role in helping and shaping the newurban middle class who consume Islam to mark their Islamic identity. It was then thatthe energetic blending between Islamic piety and capitalism occurred in contemporaryIndonesia. Islamic symbolic consumption becomes a new source of spiritualism as wellas

Photovoltaics for professionals solar electric systems marketing, design and installation

CERN Document Server

Falk, Antony; Remmers, Karl-Heinz

2007-01-01

For the building industry, the installation of photovoltaic systems has become a new field of activity. Interest in solar energy is growing and future business prospects are excellent. Photovoltaics for Professionals describes the practicalities of marketing, designing and installing photovoltaic systems, both grid-tied and stand-alone. It has been written for electricians, technicians, builders, architects and building engineers who want to get involved in this expanding industry. It answers all the beginner's questions as well as serving as a textbook and work of reference

Is it all worth it? The experiences of new PhDs on the job market, 2007–10

Science.gov (United States)

McFall, Brooke Helppie; Murray-Close, Marta; Willis, Robert J; Chen, Uniko

2016-01-01

This paper describes the job market experiences of new PhD economists, 2007-10. Using information from PhD programs' job candidate websites and original surveys, the authors present information about job candidates' characteristics, preferences and expectations; how job candidates fared at each stage of the market; and predictors of outcomes at each stage. Some information presented in this paper updates findings of prior studies. However, design features of the data used in this paper may result in more generalizable findings. This paper is unique in comparing pre-market expectations and preferences with post-market outcomes on the new PhD job market. It shows that outcomes tend to align with pre-market preferences, and candidates' expectations are somewhat predictive of their outcomes. Several analyses also shed light on sub-group differences. PMID:27616783

Conducting wine marketing research with impact in China: Guidelines for design, execution and dissemination

Directory of Open Access Journals (Sweden)

Justin Cohen

2017-12-01

Full Text Available China is the fastest growing wine market, but conducting research there is fraught with a variety of issues. This article explores some of the issues the authors have dealt with in conducting wine marketing research in China over the last five years. We discuss issues with the design of research to focus on important issues for both academics and the industry. We relate the key problems in gaining proper translation and useful sampling procedures. Finally, we provide some guidelines for communicating results effectively to different members of the wine trade.

fMRI paradigm designing and post-processing tools

International Nuclear Information System (INIS)

James, Jija S; Rajesh, PG; Chandran, Anuvitha VS; Kesavadas, Chandrasekharan

2014-01-01

In this article, we first review some aspects of functional magnetic resonance imaging (fMRI) paradigm designing for major cognitive functions by using stimulus delivery systems like Cogent, E-Prime, Presentation, etc., along with their technical aspects. We also review the stimulus presentation possibilities (block, event-related) for visual or auditory paradigms and their advantage in both clinical and research setting. The second part mainly focus on various fMRI data post-processing tools such as Statistical Parametric Mapping (SPM) and Brain Voyager, and discuss the particulars of various preprocessing steps involved (realignment, co-registration, normalization, smoothing) in these software and also the statistical analysis principles of General Linear Modeling for final interpretation of a functional activation result

Support for ITER ECRF design. Substask 3. Design and optimzation of the window unit. Final Report

International Nuclear Information System (INIS)

Thumm, M.; Braz, O.; Iatrou, C.T.; Heidinger, S.; Henry, S.; Makowski, M.; Spoerl, R.; Szczesny, J.

1999-02-01

The proposed ITER ECH window unit employs a single, edge-cooled (water, e.g. 20 C) CVD-diamond disk in a corrugated HE 11 waveguide with 52 mm inner diameter, with an outer disk diameter of 77 mm and a thickness of 1.482 mm (4 λ/2). Thermal computations show that for larger outer disk diameters the peak temperature is unaffected. Thus due to the high thermal conductivity of the diamond, the exposed window edge area does not have to be large to obtain significant heat transfer. This implies that the window diameter can be minimized which has the added benefit of reducing the cost. For a power of 1 MW at 170 GHz, a loss tangent of 1.10 -5 , a thermal conductivity of 1800 W/mK (at room temperature) and a heat transfer coefficient of 12 kW/m 2 K (water flow: 13.5 1/min, water velocity: 2 m/s, room temperature) to the cooling water the central window temperature will not be higher than approx. 45 C and the edge temperature is about 30 C. The absorbed power is 176 W. Simulations also show that steady state conditions are generally achieved in under 3 s and that a 2 MW window should be feasible. Owing to the negligible temperature dependence of the CVD-diamond loss tangent, also the approximately 100 C hot torus cooling water could be used to cool the window. Simulations of an ''encased'' window, a window in which the edge of the disk has been covered with a 0.4 mm thick layer of electrodeposited copper (tritium barrier in case of broken window disk), show that this is feasible without a significant decrease in heat transfer rate. Neutron irradiation tests were extended to fluences of 10 21 n/m 2 (E > 0.1 MeV)

A temporal interestingness measure for drug interaction signal detection in post-marketing surveillance.

Science.gov (United States)

Ji, Yanqing; Ying, Hao; Tran, John; Dews, Peter; Mansour, Ayman; Massanari, R Michael

2014-01-01

Drug-drug interactions (DDIs) can result in serious consequences, including death. Existing methods for identifying potential DDIs in post-marketing surveillance primarily rely on the FDA's (Food and Drug Administration) spontaneous reporting system. However, this system suffers from severe underreporting, which makes it difficult to timely collect enough valid cases for statistical analysis. In this paper, we study how to signal potential DDIs using patient electronic health data. Specifically, we focus on discovery of potential DDIs by analyzing the temporal relationships between the concurrent use of two drugs of interest and the occurrences of various symptoms using novel temporal association mining techniques we developed. A new interestingness measure called functional temporal interest was proposed to assess the degrees of temporal association between two drugs of interest and each symptom. The measure was employed to screen potential DDIs from 21,405 electronic patient cases retrieved from the Veterans Affairs Medical Center in Detroit, Michigan. The preliminary results indicate the usefulness of our method in finding potential DDIs for further analysis (e.g., epidemiology study) and investigation (e.g., case review) by drug safety professionals.

Spanish generation market: structure, design and results; El Mercado de Generacion Electrica en Espana: Estructura, Funcionamiento y Resultados

Energy Technology Data Exchange (ETDEWEB)

Agosti, L.; Padilla, A. J.; Requejo, A.

2007-07-01

This paper provides an overview of the structure, design and outcome of the Spanish generation market from 1998, when the market was liberalised, to date. More precisely, this paper reviews the history of the liberalisation process; describes the structure of the generation market and its evolution over time; analyses the existence of market power; and evaluates the outcome of the liberalisation process from the viewpoint of its impact on al locative efficiency, productive efficiency and dynamic efficiency. The paper concludes with a brief summary of recent regulatory reforms. (Author)

Reevaluation of the post-marketing safety of Shuxuening injection based on real-world and evidence-based evaluations.

Science.gov (United States)

Wang, Can; Shi, Qing-Ping; Ding, Feng; Jiang, Xiao-Dong; Tang, Wei; Yu, Mei-Ling; Zhu, Jian-Hua

2018-01-01

To evaluate the factors influencing suspected hypersensitivity and adverse systemic reactions after Shuxuening injection and to provide innovative ideas and methods for the reevaluation of post-marketing safety of Shuxuening. This study used a prospective, nested case-control study design, combined with a prescription sequence analysis design method. It classified patients who exhibited trigger signals after administration of Shuxuening injection as suspected allergic patients and made comparisons with patients who did not report adverse effects to calculate the correlation between relevant risk factors and suspected allergic reactions. Randomized controlled studies and cohort studies of the adverse drug reaction (ADR) of Shuxuening were performed using a computer database. Data retrieval was carried out by the foundation governing the individual database. Meta-analysis was performed by using R3.2.3 software to evaluate the ADRs of Shuxuening. The results of real-world study showed that administration of Shuxuening in combination with potassium aspartate and magnesium, atorvastatin calcium, Shengmai injection, pantoprazole sodium, or high-dose medication was a risk factor for suspected allergic reactions. Meta-analysis showed that the incidence of adverse events was 5.84% (95% CI 0.0499; 0.0674), and serious adverse reaction rate was 4.36% (95% CI 0.0188; 0.0760) when Shuxuening was used in combination with these drugs. The incidence of allergic reaction was also influenced by the vehicle, duration of treatment, single dose, and indicated vs off-label use. Risk factors for adverse reaction following the use of Shuxuening injection in patients are associated with a single dose, vehicle, type of disease, and combination with potassium aspartate, atorvastatin calcium, Shengmai injection, injection with pantoprazole sodium, and other drugs. Physicians should be careful to follow guidelines when administering this drug. We further propose that the unique methodology

Design of a real time market for regulating power. FlexPower WP1 - Report 3

Energy Technology Data Exchange (ETDEWEB)

Bang, C.; Fock, F.; Togeby, M.

2011-12-15

The FlexPower project investigates the possibility of using broadcasted dynamic electricity prices as a simple and low cost means to activating a large number of flexible small-scale power units. The aim is to provide regulating power via an aggregated response from the numerous units on a volunteer basis. The power units could for example be electrical heating and cooling units, electrical vehicles, industrial demand and micro generation. Each power unit can have its own local controller and individual business model and objective function. The optimisation of the local controls may require forecasts of the services requested by the customer (such as heat for a house or charging power for an electrical vehicle) - in terms of quantity, timing and flexibility - and forecasts of the electricity prices. Based on international 'real-time' power market experiences, new dynamic FlexPower market mechanisms to perform regulating power are designed and tested via simulations, under laboratory conditions and in the field. A dedicated simulation tool is developed for this purpose. The FlexPower regulation can never be perfect, but is expected to be able to meet some of the present and future growing demand for regulating power. As a starting point, a 5-minute power price signal, based on the actual regulation power prices, is tested. WP1 addresses the following question: 1) How could a system with a one-way price be designed? How can the FlexPower mechanism be integrated into the present electricity market, including the market for regulating power? This report describes the FlexPower concept, and gives one suggestion as to how this new market could work. How this will affect the different stakeholders is discussed, and risks and opportunities in the new market are presented. (LN)

COM1/348: Design and Implementation of a Portal for the Market of the Medical Equipment (MEDICOM)

Science.gov (United States)

Palamas, S; Vlachos, I; Panou-Diamandi, O; Marinos, G; Kalivas, D; Zeelenberg, C; Nimwegen, C; Koutsouris, D

1999-01-01

Introduction The MEDICOM system provides the electronic means for medical equipment manufacturers to communicate online with their customers supporting the Purchasing Process and the Post Market Surveillance. The MEDICOM service will be provided over the Internet by the MEDICOM Portal, and by a set of distributed subsystems dedicated to handle structured information related to medical devices. There are three kinds of these subsystems, the Hypermedia Medical Catalogue (HMC), Virtual Medical Exhibition (VME), which contains information in a form of Virtual Models, and the Post Market Surveillance system (PMS). The Universal Medical Devices Nomenclature System (UMDNS) is used to register all products. This work was partially funded by the ESPRIT Project 25289 (MEDICOM). Methods The Portal provides the end user interface operating as the MEDICOM Portal, acts as the yellow pages for finding both products and providers, providing links to the providers servers, implements the system management and supports the subsystem database compatibility. The Portal hosts a database system composed of two parts: (a) the Common Database, which describes a set of encoded parameters (like Supported Languages, Geographic Regions, UMDNS Codes, etc) common to all subsystems and (b) the Short Description Database, which contains summarised descriptions of medical devices, including a text description, the codes of the manufacturer, UMDNS code, attribute values and links to the corresponding HTML pages of the HMC, VME and PMS servers. The Portal provides the MEDICOM user interface including services like end user profiling and registration, end user query forms, creation and hosting of newsgroups, links to online libraries, end user subscription to manufacturers' mailing lists, online information for the MEDICOM system and special messages or advertisements from manufacturers. Results Platform independence and interoperability characterise the system design. A general purpose RDBMS is used

One size (never) fits all: segment differences observed following a school-based alcohol social marketing program.

Science.gov (United States)

Dietrich, Timo; Rundle-Thiele, Sharyn; Leo, Cheryl; Connor, Jason

2015-04-01

According to commercial marketing theory, a market orientation leads to improved performance. Drawing on the social marketing principles of segmentation and audience research, the current study seeks to identify segments to examine responses to a school-based alcohol social marketing program. A sample of 371 year 10 students (aged: 14-16 years; 51.4% boys) participated in a prospective (pre-post) multisite alcohol social marketing program. Game On: Know Alcohol (GO:KA) program included 6, student-centered, and interactive lessons to teach adolescents about alcohol and strategies to abstain or moderate drinking. A repeated measures design was used. Baseline demographics, drinking attitudes, drinking intentions, and alcohol knowledge were cluster analyzed to identify segments. Change on key program outcome measures and satisfaction with program components were assessed by segment. Three segments were identified; (1) Skeptics, (2) Risky Males, (3) Good Females. Segments 2 and 3 showed greatest change in drinking attitudes and intentions. Good Females reported highest satisfaction with all program components and Skeptics lowest program satisfaction with all program components. Three segments, each differing on psychographic and demographic variables, exhibited different change patterns following participation in GO:KA. Post hoc analysis identified that satisfaction with program components differed by segment offering opportunities for further research. © 2015, American School Health Association.

SSC 50 MM collider dipole cryostat single tube support post conceptual design and analysis

International Nuclear Information System (INIS)

Nicol, T.H.

1992-01-01

Superconducting Super Collider (SSC) dipole magnet cold masses are connected to the cryostat vacuum vessel at five places equally spaced along their length. Five supports limit sag of the cold assembly due to its own weight to a level consistent with the final magnet alignment specifications. The design essentially consists of two composite tubes nested within each other as a means of maximizing the thermal path length. In addition it provides an ideal way to utilize materials best suited for the temperature range over which they must operate. Filament wound S-glass is used between 300K and 80K. Filament wound graphite fiber is used between 80K and 20K and between 20K and 4.5K. S-glass is a better thermal performer above approximately 40K. Graphite composites are ideally suited for operation below 40K. The designs for the 50 mm reentrant supports are well documented in the literature. The current design of the reentrant support has two major drawbacks. First, it requires very tight dimensional control on all components; composite tubes and metal attachment parts. Second, it is expensive, with cost being driven by both the tolerance constraints and by a complex assembly procedure. It seems clear that production magnets will require a support structure which is considerably less expensive than that which is currently used. It seems clear that a design alternate for reentrant support posts will be required for production dipoles primarily due to their cost. It seems less clear that injection molded composite materials are the ideal choice. This report describes the conceptual design for a support post whose function is identical to that of the current reentrant design, which requires very few modifications to surrounding cryostat components, is thermally equivalent to the current 50 mm support post, and is nearly equivalent structurally

Natural gas market assessment: Price convergence in North American natural gas markets

International Nuclear Information System (INIS)

1995-12-01

The extent to which Canadian and U.S. natural gas markets have become integrated in the post-deregulation era was assessed. This assessment was accomplished through a statistical analysis of the price movements in Canadian and U.S. gas markets. The analysis pointed to three broad conclusions: (1) on the whole, there has been an increasing degree of integration among North American natural gas markets since price deregulation and the introduction of open access, (2) there is somewhat of a split between eastern and western markets, (3) Alberta's links are stronger with the western U.S. natural gas market than with the market in the eastern U.S. Several factors were cited as contributing to the general increase in market integration, including: (1) increased pipeline capacity and additional pipeline interconnections, coupled with the development of market hubs, (2) improved flexibility of access to pipeline transportation services, (3) improved access to market information and greater trading flexibility which has been facilitated by growing use of electronic bulletin boards and electronic trading systems. The increased market integration was claimed to have benefited both consumers and producers, and to have increased competition in both countries.. 28 refs., 14 figs

Social media marketing : Acquiring customer loyalty and relationship management using social media as a marketing channel

OpenAIRE

Saqib, Muhammad

2016-01-01

Abstract Social media is a marketing phenomenon that is growing very fast. Social media helps creating value for customers in broadcasting the advertising among social networks. Blog posts, videos, pictures, reviews and ratings all have a significant impact on marketing. The purpose of the thesis is to investigate how companies can achieve customer loyalty and customer relationship management using social media marketing and if companies can target new customers by social media. An inductive ...

Basics of case report form designing in clinical research

Directory of Open Access Journals (Sweden)

Shantala Bellary

2014-01-01

Full Text Available Case report form (CRF is a specialized document in clinical research. It should be study protocol driven, robust in content and have material to collect the study specific data. Though paper CRFs are still used largely, use of electronic CRFs (eCRFS are gaining popularity due to the advantages they offer such as improved data quality, online discrepancy management and faster database lock etc. Main objectives behind CRF development are preserving and maintaining quality and integrity of data. CRF design should be standardized to address the needs of all users such as investigator, site coordinator, study monitor, data entry personnel, medical coder and statistician. Data should be organized in a format that facilitates and simplifies data analysis. Collection of large amount of data will result in wasted resources in collecting and processing it and in many circumstances, will not be utilized for analysis. Apart from that, standard guidelines should be followed while designing the CRF. CRF completion manual should be provided to the site personnel to promote accurate data entry by them. These measures will result in reduced query generations and improved data integrity. It is recommended to establish and maintain a library of templates of standard CRF modules as they are time saving and cost-effective. This article is an attempt to describe the methods of CRF designing in clinical research and discusses the challenges encountered in this process.

Small Business Conformity with Quality Website Design Criteria in a Marketing Communication Context

Directory of Open Access Journals (Sweden)

Martine Robinson Beachboard

2017-10-01

Full Text Available Aim/Purpose: Professional companies selling persuasive-communication services via the World Wide Web need to be exemplars of effective informing practices. Their credibility is at risk if their websites do not excel in marketing message and use of medium. Their unique brands need to be expressed through website technology and content, or they cannot compete successfully. Background: Compares marketing communication consultants’ websites with expert criteria. Methodology: Content analysis of 40 advertising agency websites. Contribution: Links an evaluation of advertising agency compliance with expert website criteria to established branding constructs. Findings: Most small advertising agencies could improve their brand reputations through better compliance with experts’ recommended website design and content criteria. Recommendations for Practitioners: A hierarchy of recommendations for practitioners is offered, addressing ease and importance. Impact on Society: Clarity and credibility of message and medium improve our ability to practice effective informing. Future Research: Explore online communications of specialized populations such as digital marketing experts.

Portfolio optimization using Mixture Design of Experiments. Scheduling trades within electricity markets

International Nuclear Information System (INIS)

Oliveira, Francisco Alexandre de; Paiva, Anderson Paulo de; Lima, Jose Wanderley Marangon; Balestrassi, Pedro Paulo; Mendes, Rona Rinston Amaury

2011-01-01

Deregulation of the electricity sector has given rise to several approaches to defining optimal portfolios of energy contracts. Financial tools - requiring substantial adjustments - are usually used to determine risk and return. This article presents a novel approach to adjusting the conditional value at risk (CVaR) metric to the mix of contracts on the energy markets; the approach uses Mixture Design of Experiments (MDE). In this kind of experimental strategy, the design factors are treated as proportions in a mixture system considered quite adequate for treating portfolios in general. Instead of using traditional linear programming, the concept of desirability function is here used to combine the multi-response, nonlinear objective functions for mean with the variance of a specific portfolio obtained through MDE. The maximization of the desirability function is implied in the portfolio optimization, generating an efficient recruitment frontier. This approach offers three main contributions: it includes risk aversion in the optimization routine, it assesses interaction between contracts, and it lessens the computational effort required to solve the constrained nonlinear optimization problem. A case study based on the Brazilian energy market is used to illustrate the proposal. The numerical results verify the proposal's adequacy. (author)

Portfolio optimization using Mixture Design of Experiments. Scheduling trades within electricity markets

Energy Technology Data Exchange (ETDEWEB)

Oliveira, Francisco Alexandre de; Paiva, Anderson Paulo de; Lima, Jose Wanderley Marangon; Balestrassi, Pedro Paulo; Mendes, Rona Rinston Amaury [Federal Univ. of Itajuba, Minas Gerais (Brazil)

2011-01-15

Deregulation of the electricity sector has given rise to several approaches to defining optimal portfolios of energy contracts. Financial tools - requiring substantial adjustments - are usually used to determine risk and return. This article presents a novel approach to adjusting the conditional value at risk (CVaR) metric to the mix of contracts on the energy markets; the approach uses Mixture Design of Experiments (MDE). In this kind of experimental strategy, the design factors are treated as proportions in a mixture system considered quite adequate for treating portfolios in general. Instead of using traditional linear programming, the concept of desirability function is here used to combine the multi-response, nonlinear objective functions for mean with the variance of a specific portfolio obtained through MDE. The maximization of the desirability function is implied in the portfolio optimization, generating an efficient recruitment frontier. This approach offers three main contributions: it includes risk aversion in the optimization routine, it assesses interaction between contracts, and it lessens the computational effort required to solve the constrained nonlinear optimization problem. A case study based on the Brazilian energy market is used to illustrate the proposal. The numerical results verify the proposal's adequacy. (author)

[Taking evaluation of post-marketing as point of cut-in to promote systematic research of traditional Chinese medicine].

Science.gov (United States)

Wang, Yong-yan; Wang, Zhi-fei; Xie, Yan-ming

2014-09-01

Research on post-marketing Chinese medicine should be the systematic study from application to mechanism. Clinical evaluation is the basis of mechanism study, we can find the clue from clinical evaluation, then make a mechanism study to find the reason, then apply the results to clinic. So it is a virtuous circle. In order to achieve it, we cannot be limited to traditional Chinese medicine, we should form multi-disciplinary team under the direction of grand science thinking, try hard to put industry-university-research institute collaboration association to use, and if necessary, explore the new model of the whole nation system. An appropriate operation mechanism is very important.

Clinical Safety and Tolerability of Vildagliptin - Insights from Randomised Trials, Observational Studies and Post-marketing Surveillance.

Science.gov (United States)

Mathieu, Chantal; Kozlovski, Plamen; Paldánius, Päivi M; Foley, James E; Modgill, Vikas; Evans, Marc; Serban, Carmen

2017-08-01

Vildagliptin is one of the most extensively studied dipeptidyl peptidase-4 (DPP-4) inhibitors in terms of its clinical utility. Over the last decade, a vast panorama of evidence on the benefit-risk profile of vildagliptin has been generated in patients with type 2 diabetes mellitus (T2DM). In this article, we review the cumulative evidence on the safety of vildagliptin from the clinical development programme, as well as reports of rare adverse drug reactions detected during the post-marketing surveillance of the drug. Across clinical studies, the overall safety and tolerability profile of vildagliptin was similar to placebo, and it was supported by real-world data in a broad population of patients with T2DM, making DPP-4 inhibitors, like vildagliptin, a safe option for managing patients with T2DM.

Marketing: Managing the Marketing Mix. Courseware Evaluation for Vocational and Technical Education.

Science.gov (United States)

Fleming, Lian; And Others

This courseware evaluation rates the Marketing: Managing the Marketing Mix program developed by Control Data Limited. (This program--not contained in this document--is designed to introduce decisions made by marketing managers during the implementation phase of marketing.) Part A describes the program in terms of subject area (marketing, decision…

Security of supply in competitive electricity markets: The Nordic power market

International Nuclear Information System (INIS)

Singh, Balbir

2004-01-01

It is well known that in the absence of a complete set of markets or under conditions of monopoly and imperfect competition, optimal provision of quality can not be taken for granted. Market set in the restructured electricity markets is not complete, physical networks per definition are natural monopolies, market-power issues are yet to be resolved, not all the services supplied through the restructured frameworks are private goods and risk of government intervention is high during the times when market prices signal shortages. Sole reliance on the energy-only markets for optimal provision of security of supply under such conditions is mistaken. On the other hand, centralization of decisions for provision of reserve capacity, such as the gas-reserve capacity proposal in the Norwegian system is not an efficient substitute for missing or imperfect markets. The solution lies in the design of permanent market-mechanisms that enhance the ability of energy-only markets to handle the medium and long-term security of supply. A carefully designed reserve energy certificates mechanism is a viable alternative in this context. (Author)

78 FR 79436 - Boulder Canyon Project-Post-2017 Resource Pool

Science.gov (United States)

2013-12-30

... customers of electric utilities. The marketing criteria should include municipal corporations and political... Pool AGENCY: Western Area Power Administration, DOE. ACTION: Notice of final marketing criteria and... marketing agency of the Department of Energy (DOE), announces the Boulder Canyon Project (BCP) post-2017...

Designing realised kernels to measure the ex-post variation of equity prices in the presence of noise

DEFF Research Database (Denmark)

Barndorff-Nielsen, Ole Eiler; Hansen, Peter Reinhard; Lunde, Asger

This paper shows how to use realised kernels to carry out efficient feasible inference on the ex-post variation of underlying equity prices in the presence of simple models of market frictions. The issue is subtle with only estimators which have symmetric weights delivering consistent estimators...... with mixed Gaussian limit theorems. The weights can be chosen to achieve the best possible rate of convergence and to have an asymptotic variance which is close to that of the maximum likelihood estimator in the parametric version of this problem. Realised kernels can also be selected to (i) be analysed...... using endogenously spaced data such as that in databases on transactions, (ii) allow for market frictions which are endogenous, (iii) allow for temporally dependent noise. The finite sample performance of our estimators is studied using simulation, while empirical work illustrates their use in practice....

Open source marketing: Camel cigarette brand marketing in the "Web 2.0" world.

Science.gov (United States)

Freeman, B; Chapman, S

2009-06-01

The international trend towards comprehensive bans on tobacco advertising has seen the tobacco industry become increasingly innovative in its approach to marketing. Further fuelling this innovation is the rapid evolution and accessibility of web-based technology. The internet, as a relatively unregulated marketing environment, provides many opportunities for tobacco companies to pursue their promotional ambitions. In this paper, "open source marketing" is considered as a vehicle that has been appropriated by the tobacco industry, through a case study of efforts to design the packaging for the Camel Signature Blends range of cigarettes. Four sources are used to explore this case study including a marketing literature search, a web-based content search via the Google search engine, interviews with advertising trade informants and an analysis of the Camel brand website. RJ Reynolds (RJR) has proven to be particularly innovative in designing cigarette packaging. RJR engaged with thousands of consumers through their Camel brand website to design four new cigarette flavours and packages. While the Camel Signature Blends packaging designs were subsequently modified for the retail market due to problems arising with their cartoon-like imagery, important lessons arise on how the internet blurs the line between marketing and market research. Open source marketing has the potential to exploit advertising ban loopholes and stretch legal definitions in order to generate positive word of mouth about tobacco products. There are also lessons in the open source marketing movement for more effective tobacco control measures including interactive social marketing campaigns and requiring plain packaging of tobacco products.

An over painted oriental arts: Evaluation of the development of the Chinese renewable energy market using the wind power market as a model

International Nuclear Information System (INIS)

Yu, James; Ji, Fuxing; Zhang Ling; Chen Yushou

2009-01-01

China is now the largest CO 2 polluter in the world. However, the renewable energy policies in China are controversial and one can easily draw the wrong conclusions that Chinese renewable energy development has taken off from a surface assessment of the policies. By investigating and summarizing the first-hand experiences of participation in the Chinese renewable market (mainly wind farm development) in the past five years, this paper provides another dimension of policy analysis and independent review of the current issues facing the market. An investigation of policy changes and consequences clearly demonstrates the transformation of the Chinese renewable market. The domestic manufacturing quality and unprofessional design of wind farms made most developers' financial returns unrealistic in the wind market. Despite the difficulties and inconsistency in the system, China is tackling environmental issues seriously and heading in the right direction. With centrally controlled management, the Chinese strategies do not have to be justified financially. It is envisioned by the authors that re-organizing over 70 existing Chinese wind turbine manufacturers is unavoidable. Establishment of an internal renewable market, such as Renewable Obligation Certificate (ROC) system in the UK whose effectiveness is another subject of debate, would be an effective means by which the Chinese government in their post-2012 strategy could make the wind market more financially viable.

76 FR 81487 - Application of the Energy Planning and Management Program Power Marketing Initiative to the...

Science.gov (United States)

2011-12-28

... Management Program Power Marketing Initiative to the Boulder Canyon Project Post-2017 Remarketing AGENCY... . Information regarding Western's BCP Post-2017 marketing efforts, the Energy Management and Planning Program... Proposals. SUMMARY: The Western Area Power Administration (Western), a Federal power marketing agency of the...

Differential Fecundity, Markets and Gender Roles

OpenAIRE

Aloysius Siow

1996-01-01

Women are fecund for a shorter period of their lives than men. This paper investigates how differential fecundity interacts with marriage, labor and financial markets to affect gender roles. The main findings of the paper are: (i) Differential fecundity does not have any market invariant gender effect. (ii) Gender roles depend on competition for mates in the marriage market and the way in which ex-post differences in earnings affect that competition. (iii) Gender differences in the labor mark...

From Reciprocal Social Networks to Action Groups for Market Exchange: “Spontaneous Privatization” in Post-Communist Hungary

Directory of Open Access Journals (Sweden)

Larissa Lomnitz

2011-12-01

Full Text Available Following previous research on the significance that social networks have had for the economic and social survival of Latin American and Soviet state-employed middle classes, this paper explores the role of social networks (connections on the process of privatization and market liberalization of Post-Communist Hungary. Based on former academic studies and on field research conducted for several months in Budapest, we will try to show that social networks are central intermediary structures on which individuals and groups construct solutions that allow them to cope with the deficiencies resulting from the formal system. From this perspective we will explore the importance of manager’s connections in the first period of the Hungarian privatization process known as “spontaneous privatization”.

Market engineering - towards an interdisciplinary approach [online

OpenAIRE

Holtmann, Carsten; Neumann, Dirk; Weinhardt, Christoph

2002-01-01

The success of electronic markets does not only hinge upon scalable IT platforms combined with extensive marketing campaigns. Scientists and practitioners tend to agree that electronic markets have to be carefully designed, since even small failures in design decide on the overall success or failure of a marketplace. Unfortunately, traditional market design literature is often limited to the design of the trading rules. To solve p...

The Impact of the 2008 Global Financial Crisis on the Structure of the Transmission of Price Innovations Across Financial Markets: The Case of Southwest Asian Equity Markets

Directory of Open Access Journals (Sweden)

Liao Qunfeng

2016-06-01

Full Text Available This study examines the reaction of Southeast Asian equity markets to the transmission of price innovations from major equity markets during the pre and post periods of the 2008 global financial crisis. In particular, we examine the reaction of returns indices in Malaysia, the Philippines, South Korea, Taiwan, and Thailand as endogenous variables, and compare them to the returns indices of the U.S., the Eurozone, Japan, and China as exogenous variables. The results of VAR models indicate the combined and individual impact of the price innovations from the major equity markets on the volatility of returns of selected countries is relatively trivial during either the pre- or post-financial crisis periods. However, the individual impact of the U.S. innovations is generally higher during the post-financial crisis. The ARCH and GARCH models indicate the stock markets of Southeast Asian countries are more responsive to their own price innovations during both the pre- and the post-crisis periods, although some response to U.S. and Eurozone shocks is also observed.

Reciprocity in Online Markets: Empirical Studies of Auction and Barter Markets

Science.gov (United States)

Ye, Shun

2013-01-01

My dissertation seeks to understand how reciprocity affects transaction outcomes and mechanism design in online markets. The first essay examines negative reciprocity illustrated as feedback-revoking behavior in the eBay auction market, focusing on its impact and implications for reputation system design. I utilize the biggest policy change of…

Paying for Market Quality

DEFF Research Database (Denmark)

Anand, Amber; Tanggaard, Carsten; Weaver, Daniel G.

2009-01-01

Many financial markets, including electronic limit order markets, assign designated liquidity providers (LPs). We study the experience of the Stockholm Stock Exchange, where listed firms contract directly with LPs. Our analysis offers insights regarding situations where designated liquidity...

Marketing faculty of Bucharest Economic Studies University: historic landmarks, present and future developments

Directory of Open Access Journals (Sweden)

Călin Petrică Vegheş

2013-06-01

Full Text Available This paper aims to present the main events that left their mark on the history and evolution of the Marketing Faculty of Bucharest Economic Studies University, an academic body that this will mark its 10th anniversary this fall. As the only school dedicated exclusively to the study of marketing in Romania, as well as one of the few exclusively marketing schools in Europe, the history of the Marketing Department and, subsequently, of the Marketing Faculty overlaps in the last four decades with that of Romanian marketing higher education, as well as with the graduate transformation of Romania’s economy to a post-industrial, information-based and customer centric economy. Part of Economic Sciences domain, marketing contains a set of concepts, tools, methods and techniques through which the organization, irrespective of its profile, analyzes the environment where it lives (marketing research, sets goals and strategies to be achieved (strategic marketing planning, design and execute operational activities (marketing programs in order to maximize profits and to satisfy customer’s and society’s needs at the required level. Marketing as a strategic and operational area, captures the interest of Romanian managers and specialists of international organizations, being a source of competitive advantage and positioning of the company and its portfolio brands, in the mind and soul of current and potential customers

Strategic and Tactical Design of Competing Decentralized Supply Chain Networks with Risk-Averse Participants for Markets with Uncertain Demand

OpenAIRE

Hafezalkotob, Ashkan; Makui, Ahmad; Sadjadi, Seyed Jafar

2011-01-01

An integrated equilibrium model for tactical decisions in network design is developed. We consider a decentralized supply chain network operating in markets under uncertain demands when there is a rival decentralized chain. The primary assumption is that two chains provide partial substitutable products to the markets, and markets' demands are affected by tactical decisions such as price, service level, and advertising expenditure. Each chain consists of one risk-averse manufacturer and a set...

Changing market values? Tensions of contradicting public management discourses

DEFF Research Database (Denmark)

Plotnikof, Mie

2016-01-01

that the discursive tensions between such value-laden practices indicate a changing marketization associated with collaboration and trust, yet also competition. Research limitations/implications To research it becomes critical to advance theoretical and empirical knowledge on the constitutive effects of such complex......The purpose of this paper is to address studies of New Public Governance (NPG) as a post-New Public Management (NPM) tendency. Although NPG is considered a contrast to NPM and its market incentives, it argues that the practices emerging in tensions of NPM and NPG discourses indicate not a clear......-cut shift away from NPM, but rather changes that combine competition with collaboration and trust. Design/methodology/approach It offers a discourse approach to advance the theorizing and empirical unfolding of the tensions of contradicting, yet co-existing discourses of NPM and NPG and their effects...

Required Market Risk Premium among countries in 2012

Directory of Open Access Journals (Sweden)

Pablo Fernandez

2015-12-01

This survey also links with the Equity Premium Puzzle. It may be explained by the fact that many market participants use historical data and advice from textbooks and finance professors. Consequently, ex-ante equity premia have been high, most market prices have been consistently undervalued, and the ex-post risk premia has been also high. Many investors use historical data and textbook prescriptions to estimate the required and the expected equity premium, the undervaluation and the high ex-post risk premium are self fulfilling prophecies.

Packaging Design and Marketing Strategy of Cookie%饼干包装设计与营销策略

Institute of Scientific and Technical Information of China (English)

潘依华

2015-01-01

"The best selling product is the impression of the goods". Packaging is not only the outside protec-tion of the product, but also is a kind of marketing strategy. The quality of packaging design always impresses the effect of the advertising of the goods, and become one of the important factor in developing market. The packaging design strategy of cookie is a very logical creation progress in selling. So the research of packaging design and mar-keting strategy is meaningful to promoting market competitiveness of the cookie product.%"商品畅销的诀窍在于商品的印象."包装既是对产品的外在保护,更是一种营销策略,包装设计的好坏往往会影响到该产品的广告宣传效应,成为产品开拓市场的重要影响因素之一.饼干产品的包装设计策略是一个非常逻辑化的促销创意过程.因此,研究包装的设计及营销,对于提升饼干产品的市场竞争力具有重要的意义.

Optimal designs of small CHP plants in a market with fluctuating electricity prices

International Nuclear Information System (INIS)

Lund, H.; Andersen, A.N.

2005-01-01

Combined Heat and Power production (CHP) are essential for implementation of the climate change response objectives in many countries. In an introduction period, small CHP plants have typically been offered fixed electricity prices, but in many countries, such pricing conditions are now being replaced by spot market prices. Consequently, new methodologies and tools for the optimisation of small CHP plant designs are needed. The small CHP plants in Denmark are already experienced in optimising their electricity production against the triple tariff, which has existed for almost 10 years. Consequently, the CHP plants have long term experience in organising when to switch on and off the CHP units in order to optimise their profit. Also, the CHP owners have long term experience in designing their plants. For instance, small CHP plants in Denmark have usually invested in excess capacity on the CHP units in combination with heat storage capacity. Thereby, the plants have increased their performance in order to optimise revenues. This paper presents the Danish experience with methodologies and software tools, which have been used to design investment and operation strategies for almost all small CHP plants in Denmark during the decade of the triple tariff. Moreover, the changes in such methodologies and tools in order to optimise performance in a market with fluctuating electricity prices are presented and discussed

Hospital cost and quality performance in relation to market forces: an examination of U.S. community hospitals in the "post-managed care era".

Science.gov (United States)

Jiang, H Joanna; Friedman, Bernard; Jiang, Shenyi

2013-03-01

Managed care substantially transformed the U.S. healthcare sector in the last two decades of the twentieth century, injecting price competition among hospitals for the first time in history. However, total HMO enrollment has declined since 2000. This study addresses whether managed care and hospital competition continued to show positive effects on hospital cost and quality performance in the "post-managed care era." Using data for 1,521 urban hospitals drawn from the Healthcare Cost and Utilization Project, we examined hospital cost per stay and mortality rate in relation to HMO penetration and hospital competition between 2001 and 2005, controlling for patient, hospital, and other market characteristics. Regression analyses were employed to examine both cross-sectional and longitudinal variation in hospital performance. We found that in markets with high HMO penetration, increase in hospital competition over time was associated with decrease in mortality but no change in cost. In markets without high HMO penetration, increase in hospital competition was associated with increase in cost but no change in mortality. Overall, hospitals in high HMO penetration markets consistently showed lower average costs, and hospitals in markets with high hospital competition consistently showed lower mortality rates. Hospitals in markets with high HMO penetration also showed lower mortality rates in 2005 with no such difference found in 2001. Our findings suggest that while managed care may have lost its strength in slowing hospital cost growth, differences in average hospital cost associated with different levels of HMO penetration across markets still persist. Furthermore, these health plans appear to put quality of care on a higher priority than before.

Generation capacity adequacy in interdependent electricity markets

International Nuclear Information System (INIS)

Cepeda, Mauricio; Finon, Dominique

2011-01-01

This paper deals with the practical problems related to long-term security of supply in regional electricity markets with transmission constraints. Differences between regulatory policies and market designs in terms of generation adequacy policies may distort the normal functioning of the neighboring markets, as well as the reliability of supply. We test the effect of heterogeneous regulatory design between two interdependent markets: energy-only market, price-capped market without capacity mechanisms and price-capped markets with forward capacity contracts obligation. We rely on a long-term market simulation model in system dynamics that characterizes expansion decision in a competitive regime. The results show that differences in market designs affect both price and reliability of supply in the two markets. We examine both the short and long terms effect, and how free-riding may occur where capacity adequacy policies are adopted in one market but not the other. The main finding is that the lack of harmonization between local markets in policies to ensure capacity adequacy may lead to undesirable side effects. - Research highlights: → We model the long-term dynamic of two interdependent markets. → We examine both the short and long terms effect of heterogeneous regulatory design: energy-only market, price-capped market without capacity mechanisms and price-capped markets with forward capacity contracts obligation. → Differences in market designs affect both price and reliability of supply in the two markets. → Lack of harmonization between local markets in policies to ensure capacity adequacy may lead to undesirable side effects. → Free-riding may occur where capacity adequacy policies are adopted in one market but not the other.

Design Charrette as Methodology for Post-Disaster Participatory Reconstruction: Observations from a Case Study in Fukushima, Japan

Directory of Open Access Journals (Sweden)

Hui Zhang

2015-05-01

Full Text Available Although there has been a growing body of literature on post-disaster participatory reconstruction, a shared understanding on a participatory approach is insufficient. A design charrette is a participatory planning that is particularly suitable for situations in which multidisciplinary professionals and non-professional stakeholders collaborate to accomplish target tasks in a short period of time. The purpose of this paper is to explore the role of design charrette as a methodology in the context of post-disaster reconstruction in Japan. This will be achieved through a participatory observation on a design charrette in Minamisoma City, Japan, after the Fukushima accident. The charrette includes the participation of multiple stakeholders in intercultural, intergenerational and interdisciplinary exchanges. The contributions and constraints of the charrette are analyzed on the basis of the authors’ observation, and a strategy to improve post-disaster reconstruction charrette is thereby proposed. This study shows that the charrette is a useful method for communication and collaboration in the post-disaster context. Furthermore, it also demonstrates that assuring the participation of all key stakeholders, improving the training of participants and introducing resource analysis during the charrette’s preparatory stage are the essential conditions for the legitimacy and policy compliance of the final result.

Marketing Human Resource Development.

Science.gov (United States)

Frank, Eric, Ed.

1994-01-01

Describes three human resource development activities: training, education, and development. Explains marketing from the practitioners's viewpoint in terms of customer orientation; external and internal marketing; and market analysis, research, strategy, and mix. Shows how to design, develop, and implement strategic marketing plans and identify…

Promoting Hong Kong's Higher Education to Asian Markets: Market Segmentations and Strategies

Science.gov (United States)

Cheung, Alan C. K.; Yuen, Timothy W. W.; Yuen, Celeste Y. M.; Cheng, Yin Cheong

2010-01-01

Purpose: The main purpose of this study is threefold: to analyze the current conditions of higher education services offered in the three target markets; to conduct market segmentation analysis of these markets; and to recommend the most appropriate market entry strategies for Hong Kong's education service providers. Design/methodology/approach:…

Strategic market approach for entering the Indian solar water pump market : plan the marketing strategy for solar off-grid applications

OpenAIRE

Almanasreh, Khalil

2011-01-01

This study examines the strategic market approach for investing in solar water pumps market (SWP) in India, and Punjab state as a business case. The main research question is: What is an appropriate strategic market approach to invest in solar water pump market in India? The study focuses on the marketing strategy and strategic planning to enter the Indian market. The thesis follows the qualitative study design where the data was collected by observing the market and interviewing main sta...

Electric power market regulations in UK

International Nuclear Information System (INIS)

Federico, G.; Napolano, L.

2000-01-01

The wholesale electricity market in UK is being radically reformed, with the abolition of a centralised market (the Pool) and the introduction of a system based around bilateral trading and real-time balancing (NETA), with the aim of increasing competition in the sector. This article analyses the English experience to draw some implications on the relationship between market design, market structure and market power, and to provide some insights for the design of the future Italian market [it

Grouping notes through nodes: The functions of Post-It notes in design team cognition

DEFF Research Database (Denmark)

Dove, Graham; Abildgaard, Sille Julie Jøhnk; Biskjaer, Michael Mose

2018-01-01

We investigate the way Post-It notes support creative design team practice, focusing on how they function as cognitive externalisations that, through grouping activities, support categorisation qualities associated with semantic long-term memory. We use a multimodal approach, drawing...

Proposal for a market design featuring privatised capacity coverage; Vorschlag fuer ein Marktdesign der privatisierten Leistungsversorgung

Energy Technology Data Exchange (ETDEWEB)

Cremer, Clemens [EnBW Trading GmbH, Karlsruhe (Germany)

2013-01-15

An intensive discussion is currently waging in Germany about the necessity and possible designs of capacity mechanisms. Price-inelastic demand increases the risk of market failure, as does the policy of managing capacity coverage as if it were a public good. By privatising capacity management it becomes possible to solve problems of security of supply by market means. This involves charging the supplier with the ultimate responsibility of providing its customers with just the capacity they need at any given moment in time.

AN EMPIRICAL STUDY OF MARKETING COMMUNICATIONS EFFECTIVENESS IN SLOVENIAN MARKET

Directory of Open Access Journals (Sweden)

Damjana Jerman

2014-01-01

Full Text Available This paper deals with the value or more specifically, the contribution of marketing communications strategy to effectiveness of marketing communications and hypothesizes that marketing communications strategy correlate with the effectiveness of marketing communications. The paper consists of two parts: the theoretical framework for the role of marketing communications strategy for the effectiveness of the marketing communications and the empirical analysis, based on the primary data collected. The concept of the marketing communication effectiveness assumes that there are variables that can have a positive influence on the effectiveness of marketing communications, which incorporates facets of the marketing communication strategy and bidirectional communications. The results suggest that Slovenian organisations which design and implement marketing communication strategy, also have more effective marketing communications. The development of marketing communications strategy was correlated with increased effectiveness of marketing communications in their organisation. Managerial implications are discussed along with directions for further research.

Federal Market Information Technology in the Post Flash Crash Era: Roles for Supercomputing

Energy Technology Data Exchange (ETDEWEB)

Bethel, E. Wes; Leinweber, David; Ruebel, Oliver; Wu, Kesheng

2011-09-16

This paper describes collaborative work between active traders, regulators, economists, and supercomputing researchers to replicate and extend investigations of the Flash Crash and other market anomalies in a National Laboratory HPC environment. Our work suggests that supercomputing tools and methods will be valuable to market regulators in achieving the goal of market safety, stability, and security. Research results using high frequency data and analytics are described, and directions for future development are discussed. Currently the key mechanism for preventing catastrophic market action are “circuit breakers.” We believe a more graduated approach, similar to the “yellow light” approach in motorsports to slow down traffic, might be a better way to achieve the same goal. To enable this objective, we study a number of indicators that could foresee hazards in market conditions and explore options to confirm such predictions. Our tests confirm that Volume Synchronized Probability of Informed Trading (VPIN) and a version of volume Herfindahl-Hirschman Index (HHI) for measuring market fragmentation can indeed give strong signals ahead of the Flash Crash event on May 6 2010. This is a preliminary step toward a full-fledged early-warning system for unusual market conditions.

Designing an Incentive Contract Menu for Sustaining the Electricity Market

Directory of Open Access Journals (Sweden)

Ying Yu

2015-12-01

Full Text Available This paper designs an incentive contract menu to achieve long-term stability for electricity prices in a day-ahead electricity market. A bi-level Stackelberg game model is proposed to search for the optimal incentive mechanism under a one-leader and multi-followers gaming framework. A multi-agent simulation platform was developed to investigate the effectiveness of the incentive mechanism using an independent system operator (ISO and multiple power generating companies (GenCos. Further, a Q-learning approach was implemented to analyze and assess the response of GenCos to the incentive menu. Numerical examples are provided to demonstrate the effectiveness of the incentive contract.

Toward meso-level product-market network indices for strategic product selection and (re)design guidelines over the product life-cycle

NARCIS (Netherlands)

Vermeulen, B.; Kok, de A.G.

2010-01-01

Many methods to arrive at a product-market choice through selection and (re)design assume stationary demand and a stable range of products to pick and maximize profit trading off operational performance in manufacturing versus (under)servicing certain market segments. The determination and

Firm-Specific Marketing Capital and Job Satisfaction of Marketers: Evidence from Vietnam

Science.gov (United States)

Nguyen, Tho D.; Nguyen, Trang T. M.

2011-01-01

Purpose: Based on the resource-based view of the firm, this study aims to examine antecedents and outcomes of firm-specific marketing capital pool invested by marketers in a transition market, Vietnam. Design/methodology/approach: A sample of 528 marketers in Ho Chi Minh City was surveyed to test the theoretical model. Structural equation…

Post-Keynesianism: Evolution of Keynesian Macroeconomics in the 20 Century

Directory of Open Access Journals (Sweden)

Lyubov N. Artamonova

2016-01-01

Full Text Available The article analyzes the development of J.M. Keynes's theory in the second half of the twentieth century due to the works within the new direction of economical science - Post-Keynesianism. It is shown that in free-market economy Keynesian school based of the original Keynesian methodology requires additional studies of state regulation principles and take into account the qualitative changes in the market mechanisms. It is shown that post-Keynesianism has had a significant impact on the subject of research and has taken into account the principles of free enterprise, market pricing, level of price dynamics. All this principles allow realizing the principle of self-regulation of the market mechanism. New approaches to the post-Keynesians role of the state and state regulation combined with the freedom of entrepreneurship are analyzed. Taking into account real changes and economic crises it is necessary to analyze the main directions of development of the Keynesian model of economic regulation with a view to their effective use in shaping economic policy. There are considered the basic directions of development of post-Keynesianism such as Neo-Ricardian theory of value and prices of goods based on direct costs of production in the framework of macroeconomic model by P. Sraffa, information theory of "fundamental" uncertainty of the future by R. Klauder and the theory of financial instability hypothesis by H. Minsky. Their differences within the framework of post-Keynesianism under the subject specialization are considered. It is noted that the development of PostKeynesianism allows to present the latest research in modern Keynesian school within an interdisciplinary approach to economical problems.

Effectiveness and tolerability of parenteral testosterone undecanoate: a post-marketing surveillance study.

Science.gov (United States)

Wolf, Jan; Keipert, Dieter; Motazedi, Heiko; Ernst, Michael; Nettleship, Joanne; Gooren, Louis

2017-12-01

This observational post-marketing study of parenteral testosterone undecanoate (TU) in a non-selected population aimed to: examine the effectiveness of TU as treatment of hypogonadism; record adverse drug reactions (ADR) quantitatively particularly regarding polycythemia, prostate safety and cardiovascular-related metabolic risk factors; and verify whether recommended injection intervals apply to routine clinical practice. Eight hundred and seventy subjects from 259 outpatient units scheduled to visit the clinic six times were included. Effectiveness and tolerability of TU administration were assessed on a 4-point scale. Body weight, waist girth, blood pressure, hemoglobin levels, hematocrit, prostate-specific antigen (PSA), and digital rectal prostate examination were assessed. Over 90% of subjects completed the observational duration of 52.8 ± 9.7 weeks (mean ± SD) and 56% judged effectiveness as very good, 30.8% as good. 63.1% judged tolerability as very good, and 24.4% as good. No adverse effects on indicators of cardiovascular risk were observed. Polycythemia occurred in one subject and a supranormal hematocrit in one subject. Four subjects developed supranormal PSA levels. Prostate carcinoma was found in one subject, one subject had recurrence of a previously surgically treated prostate carcinoma, and the other two showed no indication of malignancy. Parenteral TU is safe, effective, and well-tolerated in clinical practice proving a good therapeutic option for hypogonadism.

Marketing and Distributive Education. Food Marketing Curriculum Guide

Science.gov (United States)

Northern Illinois Univ., DeKalb. Dept. of Business Education and Administration Services.

This document is one of four curriculum guides designed to provide the curriculum coordinator with a basis for planning a comprehensive program in the field of marketing as well as to provide marketing and distributive education teachers with maximum flexibility. Introductory information provides directions for using the guide and information on…