WorldWideScience

Sample records for depot operable unit

  1. Depot Maintenance: Executed Workload and Maintenance Operations at DOD Depots

    Science.gov (United States)

    2017-02-03

    capital investments, process improvements, and public-private partnerships in enclosure I. To perform our work, we reviewed 10 U.S.C. § 2464 and DOD... capital investments.7 This non-generalizable sample was selected to ensure a mix of military services (at least one per type of site—Army depot, Navy...analyzed data on workload, personnel, and capital investment for each military depot for fiscal years 2012 through 2015. We chose this time frame

  2. Computer-aided acquisition and logistics support (CALS): Concept of Operations for Depot Maintenance

    Energy Technology Data Exchange (ETDEWEB)

    Bourgeois, N.C.; Greer, D.K.

    1993-04-01

    This CALS Concept of Operations for Depot Maintenance provides the foundation strategy and the near term tactical plan for CALS implementation in the depot maintenance environment. The user requirements enumerated and the overarching architecture outlined serve as the primary framework for implementation planning. The seamless integration of depot maintenance business processes and supporting information systems with the emerging global CALS environment will be critical to the efficient realization of depot user's information requirements, and as, such will be a fundamental theme in depot implementations.

  3. Operable Units

    Data.gov (United States)

    U.S. Environmental Protection Agency — This dataset consists of operable unit data from multiple Superfund sites in U.S. EPA Region 8. These data were acquired from multiple sources at different times and...

  4. Defense Inventory: Further Analysis and Enhanced Metrics Could Improve Service Supply and Depot Operations

    Science.gov (United States)

    2016-06-01

    to be used up beyond recovery or repair—and provides these items to the services when requisitioned in support of approximately 2,400 weapon...distribution functions for depot maintenance operations varies across the services . For example, the Air Force and DLA have agreed to a local recovery ...DEFENSE INVENTORY Further Analysis and Enhanced Metrics Could Improve Service Supply and Depot Operations Report

  5. Extending Depot Length and Intervals for DDG 51 Class Ships: Examining the 72 Month Operational Cycle

    Science.gov (United States)

    2016-01-01

    model that was used in examining the effect of a 72-month cycle on the Arleigh Burke– class destroyer fleet. Chap- ter Seven presents our findings...in improving ship class maintenance management through work package documentation development. They also recognized SURFMEPP’s role in tracking work...Extending Depot Length and Intervals for DDG-51- Class Ships Examining the 72-Month Operational Cycle Roland J. Yardley, Daniel Tremblay, Brian

  6. Optimizing the Shunting Schedule of Electric Multiple Units Depot Using an Enhanced Particle Swarm Optimization Algorithm

    Science.gov (United States)

    Jin, Junchen

    2016-01-01

    The shunting schedule of electric multiple units depot (SSED) is one of the essential plans for high-speed train maintenance activities. This paper presents a 0-1 programming model to address the problem of determining an optimal SSED through automatic computing. The objective of the model is to minimize the number of shunting movements and the constraints include track occupation conflicts, shunting routes conflicts, time durations of maintenance processes, and shunting running time. An enhanced particle swarm optimization (EPSO) algorithm is proposed to solve the optimization problem. Finally, an empirical study from Shanghai South EMU Depot is carried out to illustrate the model and EPSO algorithm. The optimization results indicate that the proposed method is valid for the SSED problem and that the EPSO algorithm outperforms the traditional PSO algorithm on the aspect of optimality. PMID:27436998

  7. Interest in self-administration of subcutaneous depot medroxyprogesterone acetate in the United States.

    Science.gov (United States)

    Upadhyay, Ushma D; Zlidar, Vera M; Foster, Diana Greene

    2016-10-01

    Subcutaneous depot medroxyprogesterone acetate (DMPA-SC) is a low-dose formulation of depot medroxyprogesterone acetate (DMPA) that nonmedical personnel can administer safely and effectively. We sought to determine United States women's interest in self-administration of DMPA-SC to understand whether such use can overcome barriers to contraceptive access. We analyzed survey data on contraceptive attitudes collected in March-July 2011 from 1592 women at 13 family planning and six abortion clinics throughout the US. A mixed-effects logistic regression model with random site effects examined the determinants of interest in self-administering DMPA-SC. Overall, 21% [95% confidence interval (CI): 19%-23%] of women reported interest in self-administration. A multivariable model found that women currently using DMPA (Adjusted Odds Ratio [AOR]=3.93, 95% CI: 2.37-6.53, p<.001) and women who previously used DMPA (AOR=1.71, 95% CI: 1.26-2.32, p<.001) were more likely to have an interest in DMPA-SC than those who never used it. Women reporting difficulty obtaining or refilling a prescription were almost twice as likely to have interest in DMPA-SC as women who reported no difficulty (AOR=1.99, 95% CI: 1.43-2.77, p<.001). Women surveyed at abortion sites were more likely to report interest in self-administration than women surveyed at family planning sites (AOR=1.55, 95% CI: 1.05-2.30, p<.05). Interest in DMPA-SC was primarily driven by a desire to eliminate unnecessary return visits to a facility for repeat injections. Offering women the option to self-administer DMPA-SC at home can expand access and tailor contraceptive provision to the needs of clients, thus supporting client-centered care. To the extent that self-administration may improve contraceptive continuation, DMPA-SC can prevent unintended pregnancies among women who discontinue DMPA use because of difficulty returning for repeat injections. There is substantial interest in self-administration of DMPA-SC among current

  8. Operable Unit Boundaries

    Data.gov (United States)

    U.S. Environmental Protection Agency — This dataset consists of operable unit data from multiple Superfund sites in U.S. EPA Region 8. These data were acquired from multiple sources at different times and...

  9. CHAWS user`s guide: System description and standard operating procedures, Lexington-Blue Grass Army Depot

    Energy Technology Data Exchange (ETDEWEB)

    Martins, S.A.; Shinn, J.H. [eds.

    1993-05-01

    The Chemical Hazard Warning System (CHAWS) is designed to collect meteorological data and to display, in real time, the dispersion of hazardous chemicals that may result from an accidental release. Meteorological sensors have been placed strategically around the Lexington-Blue Grass Army Depot and are used to calculate direction and hazard distance for the release. Based on these data, arrows depicting the release direction and distance traveled are graphically displayed on a computer screen showing a site map of the facility. The objectives of CHAWS are as follows: To determine the trajectory of the center of mass of released material from the measured wind field; to calculate the dispersion of the released material based on the measured lateral turbulence intensity (sigma theta); to determine the height of the mixing zone by measurement of the inversion height and wind profiles up to an altitude of about 1 km at sites that have SODAR units installed; to archive meteorological data for potential use in climatological descriptions for emergency planning; to archive air-quality data for preparation of compliance reports; and to provide access to the data for near real time hazard analysis purposes. CHAWS sites are located at the Pine Bluff Arsenal, Arkansas, Edgewood area of Aberdeen Proving Ground, Maryland, Tooele Depot, Utah, Lexington-Blue Grass Depot, Kentucky, and Johnston Island in the Pacific. The systems vary between sites with different features and various types of hardware. The basic system, however, is the same. Nonetheless, we have tailored the manuals to the equipment found at each site.

  10. Using Genetic Algorithm For Winter Maintenance Operations: Multi Depot K-Chinese Postman Problem

    Directory of Open Access Journals (Sweden)

    İbrahim Zeki Akyurt

    2015-02-01

    Full Text Available In this study, the assignment and routing problem of one of Istanbul’s winter maintenance activities, salt pouring, was scrutinized. The starting point of the study considers the high cost of winter maintenance work, a shrinking assigned budget, high numbers of vehicles and streets to service that the increase in difficulty to solve the problem due to their high numbers. In this respect, the problem was modeled as multi depot k-Chinese postman problem, a type of arc routing problem. This mathematical model was solved by genetic algorithm. For comparison, the current solution, Clarke and Wright Algorithm and Sweep Algorithm were used.

  11. NASA Shuttle Logistics Depot (NSLD) - The application of ATE

    Science.gov (United States)

    Simpkins, Lorenz G.; Jenkins, Henry C.; Mauceri, A. Jack

    1990-01-01

    The concept of the NASA Shuttle Logistics Depot (NSLD) developed for the Space Shuttle Orbiter Program is described. The function of the NSLD at Cape Canaveral is to perform the acceptance and diagnostic testing of the Shuttle's space-rated line-replaceable units and shop-replaceable units (SRUs). The NSLD includes a comprehensive electronic automatic test station, program development stations, and assorted manufacturing support equipment (including thermal and vibration test equipment, special test equipment, and a card SRU test system). The depot activities also include the establishment of the functions for manufacturing of mechanical parts, soldering, welding, painting, clean room operation, procurement, and subcontract management.

  12. Small Unit Operations

    Science.gov (United States)

    2007-11-02

    best demonstrated value for small (< AA size) lithium - thionyl - chloride batteries (Halpert 1993). Equation (2-3) shows that the solar power...However, this energy den- sity this is only ~ 3 times larger than the demonstrated performance of the best lithium batteries , and the fuel cells are...Units 13 2.2.2 ASIC Capability 15 2.2.3 Power and Size 17 2.2.4 Cost 19 2.3 Power Sources 20 2.3.1 Batteries 21 2.3.2 Solar Augmentation

  13. Vehicle-Scheduling Model for Operation Based on Single-Depot

    Directory of Open Access Journals (Sweden)

    Jing Teng

    2015-01-01

    Full Text Available Centralized assigning of bus running between multiple lines can save operation cost of transit agency. As more big transit terminals can serve for multiple bus lines being established, coordinating the operation of these lines’ vehicles becomes more economical and perspective. This paper proposed a vehicle-scheduling model for multiple lines which share vehicle resource together and service based on the same terminal. The optimization goal is to minimize the number of vehicles while considering reducing the invalid operation time under the constraint of timetable schemes and matching time for vehicle crossing two lines. A case in Ningbo city, China, was conducted to compare the performance of the cross-line schedules with the original schedules assigning vehicles within respective lines. The optimized schedules can reduce 7.14% vehicles in need while meeting the timetable schemes of all bus lines, which indicated that the proposed model is suitable for operation practice.

  14. Makahiki+WattDepot

    DEFF Research Database (Denmark)

    Johnson, Philip M.; Xu, Yongwen; Brewer, Robert S.;

    2013-01-01

    Satisfying the radically different requirements and operating assumptions of the next generation smart grid requires new kinds of software that enable research and experimentation into the ways that electrical energy production and consumption can be collected, analyzed, visualized, and provided...... to consumers. Since 2009, we have been designing, implementing, and evaluating an open source software "stack" to facilitate this research. This software stack consists of two custom systems called WattDepot and Makahiki, along with the open source components they rely upon (Java, Restlet, Postgres, Python...

  15. The Operation Exergy Analysis for Crude Oil Depot Energy System%原油库能量系统的运行(火用)分析

    Institute of Scientific and Technical Information of China (English)

    成庆林; 王洋; 余涛; 孙晓丽

    2012-01-01

    With the increase of our country's crude oil reserves capacity, energy consumption in oil depot production will further increase. For this kind of complex and dynamic energy consumption system composed of oil storage tank, transfer pump, heating furnace and the other energy consumption unit according to certain topological relationships, the thermodynamics exergy analysis which can be used to reflect the true value and utilization degree of enengy is applied to perform a comprehensive analysis from the view of energy quality. Firstly, the sequential modular approach was used to determine the node parameters of oil depot unit module. Then according to the technological process, the gray box exergy model of oil depot system was established. Furthermore, the positive equilibrium exergy efficiency, exergy loss coefficient and anti-balance efficiency formula were given out. The case study of exergy analysis application in a certain oil depot shows that the exergy loss coefficient of furnace is 73. 99% , which is the maximum loss in oil depot. Among its various exergy losses, exergy loss of heat exchange is up to 47%. Therefore, it is important to improve energy level match in heat exchange process of furnace for increasing the exergy efficiency of oil depot.%随着我国原油储备能力的增加,原油库的生产能耗将进一步增大.对于油库这种由储油罐、输油泵、加热炉等用能单元按照一定拓扑关系连接组成的总能系统,热力学(火用)分析方法可从能质角度对其进行全面分析,反映能的真正价值和利用程度.首先采用序贯模块法确定油库系统各单元模块的节点参数,然后根据工艺流程的特点,建立了系统(火用)分析的灰箱模型,给出了正平衡(火用)效率、(火用)损系数及反平衡(火用)效率的计算式.对某油库进行(火用)分析的应用实例研究,结果表明加热炉的(炯)损系数为73.99%,是油库(火用)损最大的设备;在其各项(火用)

  16. Defense Depot Tracy Total Quality Management Plan

    Science.gov (United States)

    1989-07-01

    PAGES TQM ( Total Quality Management ), Depot Operations, Continuous Process Improvement 16. PRICE CODE 17. SECURITY CLASSIFICATION 18. SECURITY...make up our pcrceptions of Total Quality Management . Our goal is to improve those proven management processes that have brought us success while being...MANIAGEMENT F. QUALITY AUDITS OF PRODUCTS AND OPERATIONS ASSETS MANAGEMENT 00 i .......... / ~899 29 03 1 EFENSE DEPOT TACY TOTAL QUALITY MANAGEMENT PLAN

  17. 车辆段/停车场增设全自动运行功能的分析%Analysis of Automatic Train Operation Function of Depot and Parking Yard

    Institute of Scientific and Technical Information of China (English)

    黄志红

    2015-01-01

    基于目前车辆段/停车场的联锁控制方案,对车辆段/停车场作业的需求分析,通过在车辆段/停车场配置全自动运行区域,列车在该区域具备CBTC级别下的ATP/ATO功能以及ATS监控功能,并能够以ATO自动完成进出段/场的运行功能。%Based on the current interlocking control scheme for depot and parking yard, the paper makes analysis of the train operation requirements in depot and parking yard. With the arrangement of automatic train operation area in depot and parking yard, and trains acquire ATP/ATO function of CBTC level and ATS function, the trains with ATO can automatically running in and out depot and parking yard.

  18. Unit Operations for the Food Industry: Equilibrium Processes & Mechanical Operations

    OpenAIRE

    Guiné, Raquel

    2013-01-01

    Unit operations are an area of engineering that is at the same time very fascinating and most essential for the industry in general and the food industry in particular. This book was prepared in a way to achieve simultaneously the academic and practical perspectives. It is organized into two parts: the unit operations based on equilibrium processes and the mechanical operations. Each topic starts with a presentation of the fundamental concepts and principles, followed by a discussion of ...

  19. A multicenter, observational study of lanreotide depot/autogel (LAN) in patients with acromegaly in the United States: 2-year experience from the SODA registry.

    Science.gov (United States)

    Salvatori, Roberto; Gordon, Murray B; Woodmansee, Whitney W; Ioachimescu, Adriana G; Carver, Don W; Mirakhur, Beloo; Cox, David; Molitch, Mark E

    2017-07-24

    This analysis evaluates the 2-year effectiveness and safety of lanreotide depot/autogel (LAN), as well as treatment convenience and acromegaly symptom relief, from the Somatuline(®) Depot for Acromegaly (SODA) registry, a post-marketing, open-label, observational, multicenter, United States registry study. Patients with acromegaly treated with LAN were eligible for enrollment. Demographics, LAN dose, extended dosing interval (EDI) (interval of injections ≥42 days), insulin-like growth factor 1 (IGF-1), growth hormone (GH), glycated hemoglobin, adverse events (AEs), injection convenience, and symptom data were collected. As of September 29, 2014, 241 patients were enrolled in SODA. IGF-1 levels below age- and gender-adjusted upper normal limit (ULN) were achieved in 71.2% at month (M) 12 and 74.4% at M24; GH ≤2.5 µg/L in 83.3% at M12 and 80.0% at M24; GH <1.0 µg/L in 61.7% at M12 and 61.4% at M24. Both IGF-1 < ULN and GH ≤2.5 µg/L were achieved in 65.0% at M12 and 54.8% at M24; both IGF-1 < ULN and GH < 1.0 µg/L were achieved in 51.7 and 42.9% at M12 and M24, respectively. EDI regimen was 5.0% at baseline and 12.0% at M24. At M24, acromegaly symptoms appeared stable or improved. The most common AE was arthralgia (25.7%). Among 106 serious AEs reported by 42 patients, 10 were deemed related to therapy in 9 patients. At M24, 73.1% of patients rated LAN as convenient. SODA indicates 2-year biochemical control with majority of patients achieving both IGF-1 < ULN and GH ≤2.5 µg/L. LAN was generally well tolerated with no new or unexpected safety signals reported during the observation period. clinicaltrials.gov Clinical Trial Identifier: NCT00686348.

  20. Mineral operations outside the United States

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Mineral facilities and operations outside the United States compiled by the National Minerals Information Center of the USGS. This representation combines source...

  1. Unpacking Referent Units in Fraction Operations

    Science.gov (United States)

    Philipp, Randolph A.; Hawthorne, Casey

    2015-01-01

    Although fraction operations are procedurally straightforward, they are complex, because they require learners to conceptualize different units and view quantities in multiple ways. Prospective secondary school teachers sometimes provide an algebraic explanation for inverting and multiplying when dividing fractions. That authors of this article…

  2. Technology requirements for an orbiting fuel depot: A necessary element of a space infrastructure

    Science.gov (United States)

    Stubbs, R. M.; Corban, R. R.; Willoughby, A. J.

    1988-01-01

    Advanced planning within NASA has identified several bold space exploration initiatives. The successful implementation of these missions will require a supporting space infrastructure which would include a fuel depot, an orbiting facility to store, transfer and process large quantities of cryogenic fluids. In order to adequately plan the technology development programs required to enable the construction and operation of a fuel depot, a multidisciplinary workshop was convened to assess critical technologies and their state of maturity. Since technology requirements depend strongly on the depot design assumptions, several depot concepts are presented with their effect on criticality ratings. Over 70 depot-related technology areas are addressed.

  3. Technology requirements for an orbiting fuel depot - A necessary element of a space infrastructure

    Science.gov (United States)

    Stubbs, R. M.; Corban, R. R.; Willoughby, A. J.

    1988-01-01

    Advanced planning within NASA has identified several bold space exploration initiatives. The successful implementation of these missions will require a supporting space infrastructure which would include a fuel depot, an orbiting facility to store, transfer and process large quantities of cryogenic fluids. In order to adequately plan the technology development programs required to enable the construction and operation of a fuel depot, a multidisciplinary workshop was convened to assess critical technologies and their state of maturity. Since technology requirements depend strongly on the depot design assumptions, several depot concepts are presented with their effect of criticality ratings. Over 70 depot-related technology areas are addressed.

  4. The United States Military and Humanitarian Operations

    Science.gov (United States)

    1995-01-01

    stated that, "The wave of the future will be putting together task forces that will be able to respond to crisis management or humanitarian...examine three options for the military’s role in humanitaria operations at home and abroad. Option 1: Virtually Eliminate Anv Military Role This is the...humanitarian aid in almost any crisis .36 The military resists the creation of specially designated units because such specialization reduces the

  5. NIC atomic operation unit with caching and bandwidth mitigation

    Science.gov (United States)

    Hemmert, Karl Scott; Underwood, Keith D.; Levenhagen, Michael J.

    2016-03-01

    A network interface controller atomic operation unit and a network interface control method comprising, in an atomic operation unit of a network interface controller, using a write-through cache and employing a rate-limiting functional unit.

  6. Total Quality Management Implementation Plan: Defense Depot, Ogden

    Science.gov (United States)

    1989-07-01

    NUMBERS Total Quality Management Implementation Plan Defense Depot Ogden 6. AUTHOR(S) 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) 8. PERFORMING...PAGES TQM ( Total Quality Management ), Continuous Process Improvement, Depot Operations, Process Action Teams 16. PRICE CODE 17. SECURITY...034 A Message From The Commander On Total Quality Management i fully support the DLA aoproacii to Total Quality Management . As stated by General

  7. Depot Maintenance: Improvements to DODs Biennial Core Report Could Better Inform Oversight and Funding Decisions

    Science.gov (United States)

    2016-11-01

    many complex weapon systems and equipment. Recognizing the key role of the depots and the risk of overreliance on contractors, Section 2464 of...Office of the Secretary of Defense This is a work of the U.S. government and is not subject to copyright protection in the United States. The published...military depots2—public-sector facilities that are government-owned and government-operated—and private-sector contractors. Depots have a key role

  8. 21 CFR 872.6640 - Dental operative unit and accessories.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Dental operative unit and accessories. 872.6640... (CONTINUED) MEDICAL DEVICES DENTAL DEVICES Miscellaneous Devices § 872.6640 Dental operative unit and accessories. (a) Identification. A dental operative unit and accessories is an AC-powered device that is...

  9. 200-BP-5 operable unit treatability test report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-04-01

    The 200-BP-5 Operable Unit was established in response to recommendations presented in the 200 East Groundwater Aggregate Area Management Study Report (AAMSR) (DOE-RL 1993a). Recognizing different approaches to remediation, the groundwater AAMSR recommended separating groundwater from source and vadose zone operable units and subdividing 200 East Area groundwater into two operable units. The division between the 200-BP-5 and 200-PO-1 Operable Units was based principally on source operable unit boundaries and distribution of groundwater plumes derived from either B Plant or Plutonium/Uranium Extraction (PUREX) Plant liquid waste disposal sites.

  10. FPA Depot - Web Application

    Science.gov (United States)

    Avila, Edwin M. Martinez; Muniz, Ricardo; Szafran, Jamie; Dalton, Adam

    2011-01-01

    Lines of code (LOC) analysis is one of the methods used to measure programmer productivity and estimate schedules of programming projects. The Launch Control System (LCS) had previously used this method to estimate the amount of work and to plan development efforts. The disadvantage of using LOC as a measure of effort is that one can only measure 30% to 35% of the total effort of software projects involves coding [8]. In the application, instead of using the LOC we are using function point for a better estimation of hours in each software to develop. Because of these disadvantages, Jamie Szafran of the System Software Branch of Control And Data Systems (NE-C3) at Kennedy Space Canter developed a web application called Function Point Analysis (FPA) Depot. The objective of this web application is that the LCS software architecture team can use the data to more accurately estimate the effort required to implement customer requirements. This paper describes the evolution of the domain model used for function point analysis as project managers continually strive to generate more accurate estimates.

  11. Accelerating the Fourier split operator method via graphics processing units

    CERN Document Server

    Bauke, Heiko

    2010-01-01

    Current generations of graphics processing units have turned into highly parallel devices with general computing capabilities. Thus, graphics processing units may be utilized, for example, to solve time dependent partial differential equations by the Fourier split operator method. In this contribution, we demonstrate that graphics processing units are capable to calculate fast Fourier transforms much more efficiently than traditional central processing units. Thus, graphics processing units render efficient implementations of the Fourier split operator method possible. Performance gains of more than an order of magnitude as compared to implementations for traditional central processing units are reached in the solution of the time dependent Schr\\"odinger equation and the time dependent Dirac equation.

  12. UNITED STATES SPECIAL OPERATIONS FORCES IN AFRICA

    Science.gov (United States)

    2016-02-16

    and Nathan Rickard ,”Operation Serval: French Intervention in Mali,” Air Operations Division, Defence Science & Technology Organisation, http...www.cfr.org/nigeria/boko-haram/p25739. 56 James J. F. Forest, Confronting the Terrorism of Boko Haram in Nigeria, Joint Special Operations University...Best Practices.” Joint Forces Quarterly, Issue 50, 3d Quarter 2008. 30 Forest, James J. F. Confronting the Terrorism of Boko Haram in

  13. Analysis on Operation Reliability of Generating Units in 2009

    Institute of Scientific and Technical Information of China (English)

    Zhou

    2010-01-01

    This paper presents the data on operation reliability indices and relevant analyses toward China's conventional power generating units in 2009. The units brought into the statistical analysis include 100-MW or above thermal generating units, 40-MW or above hydro generating units, and all nuclear generating units. The reliability indices embodied include utilization hours, times and hours of scheduled outages, times and hours of unscheduled outages, equivalent forced outage rate and equivalent availability factor.

  14. Integrated Ground Operations Demonstration Units Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The overall goal of the project is to demonstrate cost efficient cryogenic operations on a relevant scale that can be projected onto future Spaceport architectures...

  15. Analysis of Serbian Military Riverine Units Capability for Participation in the United Nations Peacekeeping Operations

    Directory of Open Access Journals (Sweden)

    Slobodan Radojevic

    2017-06-01

    Full Text Available This paper analyses required personnel, training capacities and equipment for participation in the United Nations peacekeeping operations with the riverine elements. In order to meet necessary capabilities for engagement in United Nations peacekeeping operations, Serbian military riverine units have to be compatible with the issued UN requirements. Serbian Armed Forces have the potential to reach such requirements with the River Flotilla as a pivot for the participation in UN missions. Serbian Military Academy adopted and developed educational and training program in accordance with the provisions and recommendations of the IMO conventions and IMO model courses. Serbian Military Academy has opportunities for education and training military riverine units for participation in the United Nations peacekeeping operations. Moreover, Serbia has Multinational Operations Training Center and Peacekeeping Operations Center certified to provide selection, training, equipping and preparations of individuals and units to the United Nations multinational operations.

  16. Military Implications of United Nations Peacekeeping Operations

    Science.gov (United States)

    1993-06-01

    maintenance of law and order, protecting the delivery of humanitarian assistance, the denial of an air space and the guarantee of rights of passage . In...involve the coordinated presence of warships and combat aircraft in the disputed region. Operations to guarantee rights of passage may be mounted to ensure

  17. Study on safety operation for large hydroelectric generator unit

    Science.gov (United States)

    Yan, Z. G.; Cui, T.; Zhou, L. J.; Zhi, F. L.; Wang, Z. W.

    2012-11-01

    Hydroelectric generator unit is a complex mechanical system which is composed of hydraulic turbine and electric generator. Rotary system is supported by the bearing bracket and the reinforced concrete structures, and vibration problem can't be avoided in the process of operating. Many large-scale hydroelectric units have been damaged because of the vibration problem in recent years. As the increase of the hydraulic turbine unit capacity and water head, the safe operation of hydraulic turbine has become a focus research in many countries. The operating characteristics of the hydraulic turbine have obvious differences at different working conditions. Based on the combination of field measurement and theoretical calculation, this paper shows a deep research on the safe operation of a large-scale Francis turbine unit. Firstly, the measurements of vibration, swing, pressure fluctuation and noise were carried out at 4 different heads. And also the relationships between vibrations and pressure fluctuations at different heads and working conditions were analysed deeply. Then the scientific prediction of safe operation for the unit at high head were done based on the CFD numerical calculation. Finally, this paper shows the division of the operating zone for the hydroelectric unit. According to the experimental results (vibrations, swings, pressure fluctuations and noise) as well as the theoretical results, the operating zone of the unit has been divided into three sections: prohibited operating zone, transition operating zone and safe operating zone. After this research was applied in the hydropower station, the security and economic efficiency of unit increased greatly, and enormous economic benefits and social benefits have been obtained.

  18. Security-constrained unit commitment with flexible operating modes

    Science.gov (United States)

    Lu, Bo

    The electricity industry throughout the world, which has long been dominated by vertically integrated utilities, is facing enormous challenges. To enhance the competition in electricity industry, vertically integrated utilities are evolving into a distributed and competitive industry in which market forces drive the price of electricity and possibly reduce the net cost of supplying electrical loads through increased competition. To excel in the competition, generation companies (GENCOs) will acquire additional generating units with flexible operating capability which allows a timely response to the continuous changes in power system conditions. This dissertation considers the short-term scheduling of generating units with flexible modes of operation in security-constrained unit commitment (SCUC). Among the units considered in this study are combined cycle units, fuel switching/blending units, photovoltaic/battery system, pumped-storage units, and cascaded hydro units. The proposed security-constrained unit commitment solution will include a detailed model of transmission system which could impact the short-term scheduling of units with flexible operation modes.

  19. Sand and Gravel Operations in the United States - Direct Download

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This map layer includes sand and gravel operations in the United States. These data were obtained from information reported voluntarily to the USGS by the aggregate...

  20. Crushed Stone Operations in the United States - Direct Download

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This map layer includes crushed stone operations in the United States. These data were obtained from information reported voluntarily to the USGS by the aggregate...

  1. Impact evaluation of an orbital depot on on-orbit servicing infrastructures dedicated to modularized earth-orbiting platforms

    Science.gov (United States)

    Sarton du Jonchay, Tristan; Ho, Koki

    2017-03-01

    This paper aims to quantify the responsiveness of two on-orbit servicing infrastructures providing services to multiple serviceable platforms in coplanar medium Earth orbit (MEO) and geostationary orbit (GEO). The platforms to be serviced are assumed to be made of elementary units (EUs). EUs are small standardized structural units capable of aggregating with each other and gathering the key functions of a typical satellite within the size of a 6U cubesat. The first servicing infrastructure considered in this paper, called "Without Depot" (WoD), includes a launch vehicle and a robotic servicer. The second servicing infrastructure, called "With Depot" (WD) includes a launch vehicle, a robotic servicer and an orbital depot of EUs. The responsiveness of these infrastructures is quantified using a queueing theory-based stochastic simulation on Simulink taking into account the launch and platform random failures. The metrics used to quantify the responsiveness are the service completion rate and the average waiting time before an EU is replaced over a 10-year period of operation. With respect to those metrics, it is demonstrated that WD is more responsive than WoD. However, WD is also shown to be likely to cost more than WoD. Finally, the sensitivity of the responsiveness of WD to the capacity of the orbital depot is analyzed to find the minimum storage capacity for which WD is the most responsive. This last result could be of interest for space designers dealing with the sizing of on-orbit servicing infrastructures. We believe that the concept introduced in this paper will be a critical milestone in the design of a responsive integrated space infrastructure dedicated to the development and prosperity of a new MEO/GEO economy.

  2. Eielson Air Force Base Operable Unit 2 baseline risk assessment

    Energy Technology Data Exchange (ETDEWEB)

    Lewis, R.E.; Jarvis, T.T.; Jarvis, M.R.; Whelan, G.

    1994-10-01

    Operable Unit 2 at Eielson Air Force Base (AFB) near Fairbanks, is one of several operable units characterized by petroleum, oil, and lubricant contamination, and by the presence of organic products floating at the water table, as a result of Air Force operations since the 1940s. The base is approximately 19,270 acres in size, and comprises the areas for military operations and a residential neighborhood for military dependents. Within Operable Unit 2, there are seven source areas. These source areas were grouped together primarily because of the contaminants released and hence are not necessarily in geographical proximity. Source area ST10 includes a surface water body (Hardfill Lake) next to a fuel spill area. The primary constituents of concern for human health include benzene, toluene, ethylbenzene, and xylenes (BTEX). Monitored data showed these volatile constituents to be present in groundwater wells. The data also showed an elevated level of trace metals in groundwater.

  3. Feasibility study report for the 200-BP-1 operable unit

    Energy Technology Data Exchange (ETDEWEB)

    1993-06-01

    This feasibility study examines a range of alternatives and provides recommendations for selecting a preferred alternative for remediating contamination at the 200-BP-1 operable unit. The 200-BP-1 operable unit is located in the center of the Hanford Site along the northern boundary of the 200 East Area. The 241-BY Tank Farm is located immediately to the south of the operable unit. 200-BP-1 is a source operable unit with contaminated soils associated primarily with nine inactive cribs (known as the 216-B cribs). These cribs were used for disposal of low-level radioactive liquid waste from U Plant uranium recovery operations, and waste storage tank condensate from the adjacent 241-BY Tank Farm. The cribs used for disposal of U Plant waste were in operation from 1955--1965, and the cribs used for disposal of tank condensate were in operation from 1965--1975. In addition to the cribs, four unplanned releases of radioactive materials have occurred within the operable unit. Contaminated surface soils associated with the unplanned releases have been consolidated over the cribs and covered with clean soil to reduce contaminant migration and exposure. Discharge of wastes to the cribs has resulted in soil and groundwater contamination. The groundwater is being addressed as part of the 200 East Aggregate Area, groundwater operable unit. Contaminated soils at the site can be categorized by the types of contaminants, their distribution in the soil column, and the risk posed by the various potential exposure pathways. Below the clean soil cover, the near surface soils contain low-levels of contamination with cesium-137, radium-226, strontium-90, thorium-228, and uranium. The lifetime incremental cancer risk associated with these soils if they were exposed at the surface is 9{times}10{sup {minus}5}.

  4. Examining a Paradigm Shift in Organic Depot-Level Software Maintenance for Army Communications and Electronics Equipment

    Science.gov (United States)

    2015-05-30

    Examining a Paradigm Shift in Organic Depot-Level Software Maintenance for Army Communications and Electronics Equipment Randolph L...functional realignment of maintenance responsibilities. The results indicate that this paradigm shift in software maintenance responsibilities is...of communications and electronics equipment, can CECOM continue to operate under a paradigm of two distinct depots for software and hardware

  5. An Assessment of External Organizational Marketing at Naval Aviation Depot (NADEP) North Island

    Science.gov (United States)

    2005-12-01

    Logistics Command (ALC) at McClellan Air Force Base ( AFB ) in Sacramento , California. The second facility identified was the San Antonio ALC at Kelly...appointed BRAC Commission recommended the closure of 2 out of 5 of the United States Air Force’s aviation depots. The first was the Sacramento Aviation... AFB in San Antonio, Texas. To the commission, these two depots represented redundant production capacity that was already available at the

  6. Orbiting Depot and Reusable Lander for Lunar Transportation

    Science.gov (United States)

    Petro, Andrew

    2009-01-01

    A document describes a conceptual transportation system that would support exploratory visits by humans to locations dispersed across the surface of the Moon and provide transport of humans and cargo to sustain one or more permanent Lunar outpost. The system architecture reflects requirements to (1) minimize the amount of vehicle hardware that must be expended while maintaining high performance margins and (2) take advantage of emerging capabilities to produce propellants on the Moon while also enabling efficient operation using propellants transported from Earth. The system would include reusable single- stage lander spacecraft and a depot in a low orbit around the Moon. Each lander would have descent, landing, and ascent capabilities. A crew-taxi version of the lander would carry a pressurized crew module; a cargo version could carry a variety of cargo containers. The depot would serve as a facility for storage and for refueling with propellants delivered from Earth or propellants produced on the Moon. The depot could receive propellants and cargo sent from Earth on a variety of spacecraft. The depot could provide power and orbit maintenance for crew vehicles from Earth and could serve as a safe haven for lunar crews pending transport back to Earth.

  7. Influence of sulfur physical properties in Claus unit operation

    Energy Technology Data Exchange (ETDEWEB)

    Larraz Mora, R.; Arvelo Alvarez, R. [Chemical Engineering Dept., Univ. of la Laguna, Tenerife (Spain)

    2002-09-01

    The Claus process is an efficient way of removing H{sub 2}S from acid gas streams and it has been widely practiced in industries such as natural gas processing, oil refining and metal smelting. Increasingly strict pollution control regulations require maximum sulfur recovery and high stream factor from the Claus units in order to minimize sulfur-containing effluents. As has been widely reported Claus unit's damages mainly occur during start up and shutdown. These operations involve scheduled warm-up and cool-down of the unit, usually burning refinery fuel-gas, which if not properly made can produce severe pipe and equipment plugging as well as catalyst deactivation. Sulfur products remaining in the unit during a shutdown period can produce dramatic unit corrosion episodes diminishing sulfur recovery unit stream factor. In the present paper some guidelines are given based on sulfur physical properties singularities which help to improve start-up/shut-down procedures. (orig.)

  8. Analysis on Isolation Condenser Operation by Fukushima Daiichi Unit 1 Operators

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Man Cheol [Chungang University, Seoul (Korea, Republic of)

    2014-08-15

    Fukushima Daiichi nuclear accident resulted in the core damage in three reactors and the release of considerable amount of radioactive material to the environment, not to mention significant social impact and anti-nuclear atmosphere all around the world. This paper provides a review of the findings related to shift operators' operation of the isolation condenser in Unit 1 to examine shift operators' response to the situation. Based on the review of the findings, a situation assessment model was developed to analyze shift operators' understanding on whether core cooling was successfully performed in Unit 1 through the operation of isolation condenser. It was found that lack of information could be one of the main causes for the failure in core cooling by the IC in Unit 1. It is also recommended that the differences in the mathematical model for the situation assessment and that of the real operator need to be further investigated.

  9. Analysis on Operation Reliability of Generating Units in 2005

    Institute of Scientific and Technical Information of China (English)

    Zuo Xiaowen; Chu Xue

    2007-01-01

    @@ The weighted average equivalent availability factor of thermal power units in 2005 was 92.34%, an increase of 0.64 percentage points as compared to that in 2004. The average equivalent availability factor in 2005 was 92.22%, a decrease of 0.95 percentage points as compared to that in 2004. The nationwide operation reliability of generating units in 2005 was analyzed completely in this paper.

  10. Eurodish-Continuous Operation, System Improvement and Reference Units

    Energy Technology Data Exchange (ETDEWEB)

    Keck, T.; Schiel, W.; Heller, P.; Reinalter, W.; Gineste, J. M.; Ferriere, A.; Flamant, G.

    2006-07-01

    The 10 kWel Dish/Stirling system EuroDish was enhanced. Newly developed and improved components like the ceramic cavity insulation and the control system are described as well as a novel assembly method for the concentrator and a number of improvements and new features of the control software. Country Reference Units were built in Spain, France and Germany and are continuously operated. Operation experiences and performance data are presented. (Author)

  11. 77 FR 62247 - Dynamic Positioning Operations Guidance for Vessels Other Than Mobile Offshore Drilling Units...

    Science.gov (United States)

    2012-10-12

    ...] Dynamic Positioning Operations Guidance for Vessels Other Than Mobile Offshore Drilling Units Operating on... voluntary guidance titled ``Mobile Offshore Drilling Unit Dynamic Positioning Guidance''. The notice recommended owners and operators of Mobile Offshore Drilling Units (MODUs) follow Marine Technology...

  12. Network technology for depot modernization

    Energy Technology Data Exchange (ETDEWEB)

    Hostick, C.J.

    1990-12-01

    This report was prepared by the Pacific Northwest Laboratory to summarize existing and emerging information system technology and standards applicable to Depot System Command (DESCOM) modernization efforts. The intent of this summarization is to provide the Revitalization of Army Depots for the Year 2000 (READY 2000) team a clear understanding of the enabling information system technologies required to support effective modernization activities. Much of the information contained in this report was acquired during the last year in support of the US Army Armament, Munitions, and Chemical Command (AMCCOM) Facility Integrated Manufacturing Management System (FIMMS) project at PNL, which is targeting the modernization of plant-wide information systems at Army Ammunition Plants. The objective of information system modernization is to improve the effectiveness of an organization in performing its mission. Information system modernization strives to meet this objective by creating an environment where data is electronically captured near the source and readily available to all areas of the organization. Advanced networks, together with related information system technology, are the enabling mechanisms that make modern information system infrastructures possible. The intent of this paper is to present an overview of advanced information system network technology to support depot modernization planners in making technology management decisions. Existing and emerging Open System Interconnection (OSI) and Government Open System Interconnection Profile (GOSIP) standards are explained, as well as a brief assessment of existing products compliant with these standards. Finally, recommendations for achieving plant-wide integration using existing products are presented, and migration strategies for full OSI compliance are introduced. 5 refs., 16 figs. (JF)

  13. The watershed-scale optimized and rearranged landscape design (WORLD) model and local biomass processing depots for sustainable biofuel production: Integrated life cycle assessments

    Energy Technology Data Exchange (ETDEWEB)

    Eranki, Pragnya L.; Manowitz, David H.; Bals, Bryan D.; Izaurralde, Roberto C.; Kim, Seungdo; Dale, Bruce E.

    2013-07-23

    An array of feedstock is being evaluated as potential raw material for cellulosic biofuel production. Thorough assessments are required in regional landscape settings before these feedstocks can be cultivated and sustainable management practices can be implemented. On the processing side, a potential solution to the logistical challenges of large biorefi neries is provided by a network of distributed processing facilities called local biomass processing depots. A large-scale cellulosic ethanol industry is likely to emerge soon in the United States. We have the opportunity to influence the sustainability of this emerging industry. The watershed-scale optimized and rearranged landscape design (WORLD) model estimates land allocations for different cellulosic feedstocks at biorefinery scale without displacing current animal nutrition requirements. This model also incorporates a network of the aforementioned depots. An integrated life cycle assessment is then conducted over the unified system of optimized feedstock production, processing, and associated transport operations to evaluate net energy yields (NEYs) and environmental impacts.

  14. Refining United States Policy on Offensive Cyber Operations

    Science.gov (United States)

    2014-11-01

    address state- sponsored cyber threats with a very different set of tools ranging from diplomacy to kinetic strikes. Categorizing attacks by actor will...AIR COMMAND AND STAFF COLLEGE AIR UNIVERSITY REFINING UNITED STATES POLICY ON OFFENSIVE CYBER OPERATIONS by Max...to offensive cyber warfare, specifically cyber exploitation and cyber attack. Current domestic and international policies lack mechanisms to

  15. Semiconductor Chemical Reactor Engineering and Photovoltaic Unit Operations.

    Science.gov (United States)

    Russell, T. W. F.

    1985-01-01

    Discusses the nature of semiconductor chemical reactor engineering, illustrating the application of this engineering with research in physical vapor deposition of cadmium sulfide at both the laboratory and unit operations scale and chemical vapor deposition of amorphous silicon at the laboratory scale. (JN)

  16. Unit Operation Experiment Linking Classroom with Industrial Processing

    Science.gov (United States)

    Benson, Tracy J.; Richmond, Peyton C.; LeBlanc, Weldon

    2013-01-01

    An industrial-type distillation column, including appropriate pumps, heat exchangers, and automation, was used as a unit operations experiment to provide a link between classroom teaching and real-world applications. Students were presented with an open-ended experiment where they defined the testing parameters to solve a generalized problem. The…

  17. Biomass publications of the forest operations research unit: A synthesis

    Science.gov (United States)

    Dana Mitchell; Renee Ayala; [Compilers

    2005-01-01

    The Forest Operations Unit of the Southern Research Station has been studying biomass-related topics since 1977. This CD aids the reader by organizing these publications in one easy-to-use CD. This CD is comprised of an executive summary, two bibliographies, individual publications (in PDF format), and a keyword listing. The types of publications included on this CD...

  18. Adaptation of Professional Skills in the Unit Operations Laboratory

    Science.gov (United States)

    Rende, Deniz; Rende, Sevinc; Baysal, Nihat

    2012-01-01

    We introduce the design of three consecutive unit operations laboratory (UOL) courses that retain the academic rigor of the course while incorporating skills essential for professional careers, such as ability to propose ideas, develop practical solutions, participate in teamwork, meet deadlines, establish communication between technical support…

  19. The Numerical Investigation of Temperature and Velocity Distribution in the High-Bay Depot

    Directory of Open Access Journals (Sweden)

    Xuehong Wu

    2014-07-01

    Full Text Available High-bay depot plays an important role in the storage industry. Due to large and high space of high-bay depot, it is difficult to make temperature distribution uniform, which will influence the storage time of raw materials. In this paper, the aim is to find the reasonable air supply and energy-saving method; a supply-air method of high-bay depot is investigated as an example. The results show the radius and spacing of the supply-air inlet have great influence on temperature distribution. The temperature nonuniformity coefficient of summer is smaller than that of winter. The investigated results can provide a theoretical reference for the high-bay depot design and economic operation.

  20. Centrifugal microfluidic platforms: advanced unit operations and applications.

    Science.gov (United States)

    Strohmeier, O; Keller, M; Schwemmer, F; Zehnle, S; Mark, D; von Stetten, F; Zengerle, R; Paust, N

    2015-10-01

    Centrifugal microfluidics has evolved into a mature technology. Several major diagnostic companies either have products on the market or are currently evaluating centrifugal microfluidics for product development. The fields of application are widespread and include clinical chemistry, immunodiagnostics and protein analysis, cell handling, molecular diagnostics, as well as food, water, and soil analysis. Nevertheless, new fluidic functions and applications that expand the possibilities of centrifugal microfluidics are being introduced at a high pace. In this review, we first present an up-to-date comprehensive overview of centrifugal microfluidic unit operations. Then, we introduce the term "process chain" to review how these unit operations can be combined for the automation of laboratory workflows. Such aggregation of basic functionalities enables efficient fluidic design at a higher level of integration. Furthermore, we analyze how novel, ground-breaking unit operations may foster the integration of more complex applications. Among these are the storage of pneumatic energy to realize complex switching sequences or to pump liquids radially inward, as well as the complete pre-storage and release of reagents. In this context, centrifugal microfluidics provides major advantages over other microfluidic actuation principles: the pulse-free inertial liquid propulsion provided by centrifugal microfluidics allows for closed fluidic systems that are free of any interfaces to external pumps. Processed volumes are easily scalable from nanoliters to milliliters. Volume forces can be adjusted by rotation and thus, even for very small volumes, surface forces may easily be overcome in the centrifugal gravity field which enables the efficient separation of nanoliter volumes from channels, chambers or sensor matrixes as well as the removal of any disturbing bubbles. In summary, centrifugal microfluidics takes advantage of a comprehensive set of fluidic unit operations such as

  1. Space Transportation Infrastructure Supported By Propellant Depots

    Science.gov (United States)

    Smitherman, David; Woodcock, Gordon

    2012-01-01

    A space transportation infrastructure is described that utilizes propellant depot servicing platforms to support all foreseeable missions in the Earth-Moon vicinity and deep space out to Mars. The infrastructure utilizes current expendable launch vehicle (ELV) systems such as the Delta IV Heavy, Atlas V, and Falcon 9, for all crew, cargo, and propellant launches to orbit. Propellant launches are made to Low-Earth-Orbit (LEO) Depot and an Earth-Moon Lagrange Point 1 (L1) Depot to support a new reusable in-space transportation vehicles. The LEO Depot supports missions to Geosynchronous Earth Orbit (GEO) for satellite servicing and to L1 for L1 Depot missions. The L1 Depot supports Lunar, Earth-Sun L2 (ESL2), Asteroid and Mars Missions. New vehicle design concepts are presented that can be launched on current 5 meter diameter ELV systems. These new reusable vehicle concepts include a Crew Transfer Vehicle (CTV) for crew transportation between the LEO Depot, L1 Depot and missions beyond L1; a new reusable lunar lander for crew transportation between the L1 Depot and the lunar surface; and Mars orbital Depot are based on International Space Station (ISS) heritage hardware. Data provided includes the number of launches required for each mission utilizing current ELV systems (Delta IV Heavy or equivalent) and the approximate vehicle masses and propellant requirements. Also included is a discussion on affordability with ideas on technologies that could reduce the number of launches required and thoughts on how this infrastructure include competitive bidding for ELV flights and propellant services, developments of new reusable in-space vehicles and development of a multiuse infrastructure that can support many government and commercial missions simultaneously.

  2. Occupational Exposure of Petroleum Depot Workers to BTEX Compounds

    Directory of Open Access Journals (Sweden)

    M Rezazadeh Azari

    2011-12-01

    Full Text Available Background: Benzene, toluene, ethylbenzene and xylene (BTEX are the most important toxic volatile compounds in the air and could be easily absorbed through the respiratory tract. In recent years, the risk of exposure to BTEX compounds, especially benzene as a carcinogen, has been considered in petroleum depot stations. Objective: To assess the occupational exposure of petroleum depot workers in Iran to BTEX compounds. Methods: After completing a questionnaire and assessing occupational exposure to BTEX compounds, 78 (46 exposed and 32 non-exposed depot workers were randomly selected to participate in this study. Air sampling and analysis of BTEX was conducted according to the NIOSH method No. 1501. Analysis of urinary hippuric acid, as an indicator of toluene exposure, was carried out according to NIOSH method No. 8300. Personal monitoring of the high exposure group to BTEX compounds was repeated to verify the results obtained in the first phase of the monitoring. Results: Among the 9 operating groups studied, occupational exposure to benzene and toluene was higher in quality control and gasoline loading operators—the median exposure ranged from 0.16 to 1.63 ppm for benzene and 0.2 to 2.72 ppm for toluene. Median exposure of other group members to BTEX compounds was below the detection limit of analytical method (0.07, 0.06, 0.05, and 0.05 ppm, respectively. The level of toluene exposure measured showed correlation with neither post-shift urinary hippuric acid (Spearman's rho=0.128, p=0.982 nor with the difference between post- and pre-shift urinary hippuric acid (Spearman's rho=0.089, p=0.847 in depot operational workers. Conclusion: Gasoline loading operators are exposed to a relatively high level of benzene.

  3. Measures of coherence-generating power for quantum unital operations

    Science.gov (United States)

    Zanardi, Paolo; Styliaris, Georgios; Campos Venuti, Lorenzo

    2017-05-01

    Given an orthonormal basis B in a d -dimensional Hilbert space and a unital quantum operation E acting on it, one can define a nonlinear mapping that associates with E a d ×d real-valued matrix that we call the coherence matrix of E with respect to B . This is the Gram matrix of the coherent part of the basis projections of B under E . We show that one can use this coherence matrix to define vast families of measures of the coherence-generating power (CGP) of the operation. These measures have a natural geometrical interpretation as separation of E from the set of incoherent unital operations. The probabilistic approach to CGP discussed in P. Zanardi et al. [Phys. Rev. A 95, 052306 (2017)., 10.1103/PhysRevA.95.052306] can be reformulated and generalized, introducing, alongside the coherence matrix, another d ×d real-valued matrix, the simplex correlation matrix. This matrix describes the relevant statistical correlations in the input ensemble of incoherent states. Contracting these two matrices, one finds CGP measures associated with the process of preparing the given incoherent ensemble and processing it with the chosen unital operation. Finally, in the unitary case, we discuss how these concepts can be made compatible with an underlying tensor product structure by defining families of CGP measures that are additive.

  4. Advanced Transport Operating System (ATOPS) control display unit software description

    Science.gov (United States)

    Slominski, Christopher J.; Parks, Mark A.; Debure, Kelly R.; Heaphy, William J.

    1992-01-01

    The software created for the Control Display Units (CDUs), used for the Advanced Transport Operating Systems (ATOPS) project, on the Transport Systems Research Vehicle (TSRV) is described. Module descriptions are presented in a standardized format which contains module purpose, calling sequence, a detailed description, and global references. The global reference section includes subroutines, functions, and common variables referenced by a particular module. The CDUs, one for the pilot and one for the copilot, are used for flight management purposes. Operations performed with the CDU affects the aircraft's guidance, navigation, and display software.

  5. Stability Analysis for Operation of DG Units in Smart Grids

    DEFF Research Database (Denmark)

    Pouresmaeil, Edris; Shaker, Hamid Reza; Mehrasa, Majid

    2015-01-01

    This paper presents a multifunction control strategy for the stable operation of Distributed Generation (DG) units during grid integration. The proposed control model is based on Direct Lyapunov Control (DLC) theory and provides a stable region for the appropriate operation of DG units during grid...... integration. Using DLC technique in DG technology can provide the continuous injection of maximum active power in fundamental frequency from the DG source to the grid, compensating all reactive power and harmonic current components of grid-connected loads through the integration of DG link into the grid....... Application of this concept can guarantee to reduce the stress on the grid during the energy demand peak. Simulation results are presented to demonstrate the proficiency and performance of the proposed DLC technique in DG technology....

  6. Development and operation of 1 MW wind power unit

    Energy Technology Data Exchange (ETDEWEB)

    Seleznev, I.; Lavrov, V. [Machine-building Design Bureau, (Russian Federation)

    1996-12-31

    Development of wind power units (WPUs), which operate on renewable wind power, as well as combined power sources including WPUs, have an important national economic significance in the Russian Federation, particularly in the areas of construction and operation of nuclear power plants, hydro-electric stations and other traditional power plants. Development of WPUs of high power level is a complicated task, and the solution requires investigations in the areas of experimental design, technology, and the organization of industrial production. Initially, the problem of the development of large diameter propellers, power electric equipment, reducers and drive mechanisms, automatic control devices, and control and diagnostic system need to be solved. This report covers the basic results and directions of the work of the Machine-building Design Bureau `Raduga` in the field of wind power engineering as well as the basic performance of the units. (author). 7 figs.

  7. [Operational units for health risk management (patient safety)].

    Science.gov (United States)

    Pardo Hernández, A; Claveria Fontán, A; García Urbaneja, M; López Barba, J

    2008-12-01

    In 1995 INSALUD began to develop performance measures in the field of risk management, and following transfer of powers to the regions, these led to the development of operational units in individual healthcare centres. These units, which consist of a group of health professionals, including managers, aim to identify, evaluate, analyse and deal with health risks, to enhance patient safety. Their organisational structure can vary in accordance with the needs, resources and philosophy of each individual organisation. This paper presents the experience of the risk management units developed in four Spanish regions: Madrid, the Basque Country, Galicia and INGESA (Ceuta and Melilla). It also includes reflections on assessment of their impact and on their future role in improving safety in healthcare services.

  8. Analysis of viral clearance unit operations for monoclonal antibodies.

    Science.gov (United States)

    Miesegaes, George; Lute, Scott; Brorson, Kurt

    2010-06-01

    Demonstration of viral clearance is a critical step in assuring the safety of biotechnology products. We generated a viral clearance database that contains product information, unit operation process parameters, and viral clearance data from monoclonal antibody and antibody-related regulatory submissions to FDA. Here we present a broad overview of the database and resulting analyses. We report that the diversity of model viruses tested expands as products transition to late-phase. We also present averages and ranges of viral clearance results by Protein A and ion exchange chromatography steps, low pH chemical inactivation, and virus filtration, focusing on retro- and parvoviruses. For most unit operations, an average log reduction value (LRV, a measure of clearance power) for retrovirus of >4 log(10) were measured. Cases where clearance data fell outside of the anticipated range (i.e., outliers) were rationally explained. Lastly, a historical analysis did not find evidence of any improvement trend in viral clearance over time. The data collectively suggest that many unit operations in general can reliably clear viruses.

  9. Depot Maintenance: Improved Strategic Planning Needed to Ensure That Army and Marine Corps Depots Can Meet Future Maintenance Requirements

    Science.gov (United States)

    2009-09-01

    of Representatives DEPOT MAINTENANCE Improved Strategic Planning Needed to Ensure That Army and Marine Corps Depots Can Meet Future...Depot Maintenance. Improved Strategic Planning Needed to Ensure That Army and Marine Corps Depots Can Meet Future Maintenance Requirements 5a... Strategic Planning Needed to Ensure That Army and Marine Corps Depots Can Meet Future Maintenance Requirements Highlights of GAO-09-865, a report to

  10. WTP Waste Feed Qualification: Glass Fabrication Unit Operation Testing Report

    Energy Technology Data Exchange (ETDEWEB)

    Stone, M. E. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL). Hanford Missions Programs; Newell, J. D. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL). Process Technology Programs; Johnson, F. C. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL). Engineering Process Development; Edwards, T. B. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL). Engineering Process Development

    2016-07-14

    The waste feed qualification program is being developed to protect the Hanford Tank Waste Treatment and Immobilization Plant (WTP) design, safety basis, and technical basis by assuring waste acceptance requirements are met for each staged waste feed campaign prior to transfer from the Tank Operations Contractor to the feed receipt vessels inside the Pretreatment Facility. The Waste Feed Qualification Program Plan describes the three components of waste feed qualification: 1. Demonstrate compliance with the waste acceptance criteria 2. Determine waste processability 3. Test unit operations at laboratory scale. The glass fabrication unit operation is the final step in the process demonstration portion of the waste feed qualification process. This unit operation generally consists of combining each of the waste feed streams (high-level waste (HLW) and low-activity waste (LAW)) with Glass Forming Chemicals (GFCs), fabricating glass coupons, performing chemical composition analysis before and after glass fabrication, measuring hydrogen generation rate either before or after glass former addition, measuring rheological properties before and after glass former addition, and visual observation of the resulting glass coupons. Critical aspects of this unit operation are mixing and sampling of the waste and melter feeds to ensure representative samples are obtained as well as ensuring the fabrication process for the glass coupon is adequate. Testing was performed using a range of simulants (LAW and HLW simulants), and these simulants were mixed with high and low bounding amounts of GFCs to evaluate the mixing, sampling, and glass preparation steps in shielded cells using laboratory techniques. The tests were performed with off-the-shelf equipment at the Savannah River National Laboratory (SRNL) that is similar to equipment used in the SRNL work during qualification of waste feed for the Defense Waste Processing Facility (DWPF) and other waste treatment facilities at the

  11. Forecasting Wartime Depot-Level Component Workloads.

    Science.gov (United States)

    1985-01-01

    Baseline Study the NALC assumed that all failures sent to the depot must be repaired, despite the fact that ASO plans to buy war reserve stock to...be bought to fill these demands. Note, however, that the stock buy for the 0 exponential pipeline case is somewhat less than that required for the...daily demands on depot supply to BCN rates Minimum workload 200 - Baseline- 23 month scenario -Low BCM 175 - .. . High BCM7i. -- Hgh BCM half sortie 150

  12. Method and apparatus for operating an improved thermocline storage unit

    Science.gov (United States)

    Copeland, Robert J.

    1985-01-01

    A method and apparatus for operating a thermocline storage unit in which an insulated barrier member is provided substantially at the interface region between the hot and cold liquids in the storage tank. The barrier member physically and thermally separates the hot and cold liquids substantially preventing any diffusing or mixing between them and substantially preventing any heat transfer therebetween. The barrier member follows the rise and fall of the interface region between the liquids as the tank is charged and discharged. Two methods of maintaining it in the interface region are disclosed. With the structure and operation of the present invention and in particular the significant reduction in diffusing or mixing between the hot and cold liquids as well as the significant reduction in the thermal heat transfer between them, the performance of the storage tank is improved. More specifically, the stability of the interface region or thermocline is enhanced and the thickness of the thermocline is reduced producing a corresponding increase in the steepness of the temperature gradient across the thermocline and a more efficiently operating thermocline storage unit.

  13. The United States national volcanic ash operations plan for aviation

    Science.gov (United States)

    Albersheim, Steven; Guffanti, Marianne

    2009-01-01

    Volcanic-ash clouds are a known hazard to aviation, requiring that aircraft be warned away from ash-contaminated airspace. The exposure of aviation to potential hazards from volcanoes in the United States is significant. In support of existing interagency operations to detect and track volcanic-ash clouds, the United States has prepared a National Volcanic Ash Operations Plan for Aviation to strengthen the warning process in its airspace. The US National Plan documents the responsibilities, communication protocols, and prescribed hazard messages of the Federal Aviation Administration, National Oceanic and Atmospheric Administration, US Geological Survey, and Air Force Weather Agency. The plan introduces a new message format, a Volcano Observatory Notice for Aviation, to provide clear, concise information about volcanic activity, including precursory unrest, to air-traffic controllers (for use in Notices to Airmen) and other aviation users. The plan is online at http://www.ofcm.gov/p35-nvaopa/pdf/FCM-P35-2007-NVAOPA.pdf. While the plan provides general operational practices, it remains the responsibility of the federal agencies involved to implement the described procedures through orders, directives, etc. Since the plan mirrors global guidelines of the International Civil Aviation Organization, it also provides an example that could be adapted by other countries.

  14. Article separation apparatus and method for unit operations

    Science.gov (United States)

    Pardini, Allan F.; Gervais, Kevin L.; Mathews, Royce A.; Hockey, Ronald L.

    2010-06-22

    An apparatus and method are disclosed for separating articles from a group of articles. The apparatus includes a container for containing one or more articles coupled to a suitable fluidizer for suspending articles within the container and transporting articles to an induction tube. A portal in the induction tube introduces articles singly into the induction tube. A vacuum pulls articles through the induction tube separating the articles from the group of articles in the container. The apparatus and method can be combined with one or more unit operations or modules, e.g., for inspecting articles, assessing quality of articles, or ascertaining material properties and/or parameters of articles, including layers thereof.

  15. Feasibility Study for Operable Unit 7-13/14

    Energy Technology Data Exchange (ETDEWEB)

    K. Jean Holdren

    2007-05-29

    The Subsurface Disposal Area is a radioactive waste landfill located within the Radioactive Waste Management Complex at the Idaho National Laboratory Site in southeastern Idaho. This Feasibility Study for Operable Unit 7-13/14 analyzes options for mitigating risks to human health and the environment associated with the landfill. Analysis is conducted in accordance with the Comprehensive Environmental Response, Compensation, and Liability Act, using nine evaluation criteria to develop detailed and comparative analysis of five assembled alternatives. Assembled alternatives are composed of discrete modules. Ultimately, decision-makers will select, recombine, and sum various modules into an optimized preferred alternative and final remedial decision.

  16. CTS (Hermes): United States experiments and operations summary

    Science.gov (United States)

    Donoughe, P. L.; Hunczak, H. R.

    1977-01-01

    The Communications Technology Satellite, launched in January 1976 and embodying the highest power transmitter in a communications satellite, was considered. As a joint program between the U.S. and Canada, close coordination of the two countries was necessitated since the management and control of experiments were done in real time. Criteria used by NASA for acceptance of the United States experiments are noted and acceptance procedures are discussed. The category for each accepted experiment is given. The modus operandi employed for the U.S. experiments in the areas of management, coordination, liaison, and real time operation are described. Some of the highlights associated with satellite utilization are given.

  17. Toward a warfighter's associate: eliminating the operator control unit

    Science.gov (United States)

    Everett, Hobart R.; Pacis, Estrellina B.; Kogut, Greg; Farrington, Nathan M.; Khurana, S.

    2004-12-01

    In addition to the challenges of equipping a mobile robot with the appropriate sensors, actuators, and processing electronics necessary to perform some useful function, there coexists the equally important challenge of effectively controlling the system"s desired actions. This need is particularly critical if the intent is to operate in conjunction with human forces in a military application, as any low-level distractions can seriously reduce a warfighter"s chances of survival in hostile environments. Historically there can be seen a definitive trend towards making the robot smarter in order to reduce the control burden on the operator, and while much progress has been made in laboratory prototypes, all equipment deployed in theatre to date has been strictly teleoperated. There exists a definite tradeoff between the value added by the robot, in terms of how it contributes to the performance of the mission, and the loss of effectiveness associated with the operator control unit. From a command-and-control perspective, the ultimate goal would be to eliminate the need for a separate robot controller altogether, since it represents an unwanted burden and potential liability from the operator"s perspective. This paper introduces the long-term concept of a supervised autonomous Warfighter"s Associate, which employs a natural-language interface for communication with (and oversight by) its human counterpart. More realistic near-term solutions to achieve intermediate success are then presented, along with actual results to date. The primary application discussed is military, but the concept also applies to law enforcement, space exploration, and search-and-rescue scenarios.

  18. Ensuring Operational Readiness: Private Military Contractor Support for the United States Air Force

    Science.gov (United States)

    2017-03-15

    Ensuring Operational Readiness: Private Military Contractor Support for the United States Air Force A Monograph by Maj Stephen P. Joca United...States Air Force School of Advanced Military Studies United States Army Command and General Staff College Fort Leavenworth, Kansas 2017 Approved...Operational Readiness: Private Military Contractor Support for the United States Air Force Approved by: __________________________________, Monograph

  19. Particle Emissions from District Heating Units Operating on Solid Biofuels

    Energy Technology Data Exchange (ETDEWEB)

    Wierzbicka, Aneta [Lund Inst. of Technology (Sweden). Div. of Ergonomics and Aerosol Technology

    2005-06-01

    With the increasing interest in the use of biofuels for heat and energy generation there is a growing concern about emissions from their combustion. It has been shown that biofuel furnaces emit relatively high quantities of particulate matter in comparison to natural gas and light fuel oil furnaces. Majority of the emitted particulates are smaller than 10 {mu}m with high contribution of fine (<2.5 {mu}m) and submicron (<1 {mu}m) particles. These fine particles tend to be the most troublesome: in ambient air they have been associated with adverse health effects. Submicron particles are difficult to capture in the available particle removal technologies. The aim of this study was to characterise particle emissions from district heating units operating on three commonly used biofuels, namely sawdust. pellets and forest residues. Boilers were of moving grate type. with the maximum thermal output between 1 and 1.5 MW. The measurements were done after multi cyclones, the only particle removal devices installed, therefore the direct emissions to ambient air were characterised. Influence of type of the fuel and operation load on particle emissions was investigated. Furthermore, collection efficiencies of electrostatic precipitator (ESP) and flue gas condenser, used particle separation devices in 6 MW unit, were investigated. It has been shown that in all cases large amounts of fuel particles containing heavy metals are being emitted to the atmosphere, even though the studied district heating units meet the current mass concentration emission limit requirements. Total number concentration of emitted particles with aerodynamic diameter smaller than 5 {mu}m ranged from 3 to 8x10{sup 7} particles/cm{sub n}{sup 3} with the slightly higher values from combustion of forest residues. Both mass and total number concentrations were dominated by submicron particles contribution. Elements determined by Particle Induced X-rays Emission (PIXE) analysis (Z>12) contributed to 21-34 % of

  20. Fatality trends in United Nations Peacekeeping Operations, 1948-1998.

    Science.gov (United States)

    Seet, B; Burnham, G M

    2000-08-02

    The rising number of deaths among United Nations (UN) peacekeeping forces after the Cold War has made some troop-contributing countries hesitant to participate in peacekeeping operations. While the number and scale of missions have increased, no data have demonstrated a parallel increase in risks to peacekeepers. To determine the association of characteristics of UN peacekeeping operations with risks and mortality rates among UN peacekeeping forces in both the Cold War and post-Cold War periods. Descriptive analysis of 1559 personnel deaths during 49 UN peacekeeping missions from 1948-1998 based on the casualty database maintained by Department of Peacekeeping Operations, UN Headquarters. Number and percentage of deaths by circumstance, total crude death rate, and crude death rate and relative risk of death by circumstance (hostile acts, unintentional violence, and illness or other causes) and time period (Cold War vs post-Cold War), geographic region, and nature of peacekeeping response; and regression analysis of mission variables (strength, duration, and humanitarian mandate) associated with total number of deaths. More deaths have occurred among UN peacekeeping forces in the past decade alone than in the previous 40 years of UN peacekeeping (807 vs 752), but crude death rates did not differ significantly by time period (Cold War vs post-Cold War, 21.8 vs 21. 2 deaths per 10,000 person-years; P =.58), level of peacekeeping response, or for geographic regions other than East Europe and Central America, where rates were lower (PCold War (relative risk [RR] 1. 51; 95% confidence interval [CI], 1.22-1.88), while rates for deaths caused by unintentional violence decreased (RR, 0.79; 95% CI, 0.67-0. 94) but remain high, particularly in the Middle East and Asia (RR, 1. 39; 95% CI, 1.15-1.69). Regression analysis showed a significant association between number of deaths and the strength (PCold War rather than increased RR of death. Post-Cold War peacekeeping personnel

  1. Operations research in intensive care unit management: a literature review.

    Science.gov (United States)

    Bai, Jie; Fügener, Andreas; Schoenfelder, Jan; Brunner, Jens O

    2016-08-12

    The intensive care unit (ICU) is a crucial and expensive resource largely affected by uncertainty and variability. Insufficient ICU capacity causes many negative effects not only in the ICU itself, but also in other connected departments along the patient care path. Operations research/management science (OR/MS) plays an important role in identifying ways to manage ICU capacities efficiently and in ensuring desired levels of service quality. As a consequence, numerous papers on the topic exist. The goal of this paper is to provide the first structured literature review on how OR/MS may support ICU management. We start our review by illustrating the important role the ICU plays in the hospital patient flow. Then we focus on the ICU management problem (single department management problem) and classify the literature from multiple angles, including decision horizons, problem settings, and modeling and solution techniques. Based on the classification logic, research gaps and opportunities are highlighted, e.g., combining bed capacity planning and personnel scheduling, modeling uncertainty with non-homogenous distribution functions, and exploring more efficient solution approaches.

  2. Techno-economic analysis of decentralized biomass processing depots.

    Science.gov (United States)

    Lamers, Patrick; Roni, Mohammad S; Tumuluru, Jaya S; Jacobson, Jacob J; Cafferty, Kara G; Hansen, Jason K; Kenney, Kevin; Teymouri, Farzaneh; Bals, Bryan

    2015-10-01

    Decentralized biomass processing facilities, known as biomass depots, may be necessary to achieve feedstock cost, quantity, and quality required to grow the future U.S. bioeconomy. In this paper, we assess three distinct depot configurations for technical difference and economic performance. The depot designs were chosen to compare and contrast a suite of capabilities that a depot could perform ranging from conventional pelleting to sophisticated pretreatment technologies. Our economic analyses indicate that depot processing costs are likely to range from ∼US$30 to US$63 per dry metric tonne (Mg), depending upon the specific technology implemented and the energy consumption for processing equipment such as grinders and dryers. We conclude that the benefits of integrating depots into the overall biomass feedstock supply chain will outweigh depot processing costs and that incorporation of this technology should be aggressively pursued.

  3. FOCU:S--future operator control unit: soldier

    Science.gov (United States)

    O'Brien, Barry J.; Karan, Cem; Young, Stuart H.

    2009-05-01

    The U.S. Army Research Laboratory's (ARL) Computational and Information Sciences Directorate (CISD) has long been involved in autonomous asset control, specifically as it relates to small robots. Over the past year, CISD has been making strides in the implementation of three areas of small robot autonomy, namely platform autonomy, Soldier-robot interface, and tactical behaviors. It is CISD's belief that these three areas must be considered as a whole in order to provide Soldiers with useful capabilities. In addressing the Soldier-robot interface aspect, CISD has begun development on a unique dismounted controller called the Future Operator Control Unit: Soldier (FOCU:S) that is based on an Apple iPod Touch. The iPod Touch's small form factor, unique touch-screen input device, and the presence of general purpose computing applications such as a web browser combine to give this device the potential to be a disruptive technology. Setting CISD's implementation apart from other similar iPod or iPhone-based devices is the ARL software that allows multiple robotic platforms to be controlled from a single OCU. The FOCU:S uses the same Agile Computing Infrastructure (ACI) that all other assets in the ARL robotic control system use, enabling automated asset discovery on any type of network. Further, a custom ad hoc routing implementation allows the FOCU:S to communicate with the ARL ad hoc communications system and enables it to extend the range of the network. This paper will briefly describe the current robotic control architecture employed by ARL and provide short descriptions of existing capabilities. Further, the paper will discuss FOCU:S specific software developed for the iPod Touch, including unique capabilities enabled by the device's unique hardware.

  4. Is fumigation enough for air conditioning units in operation theatres and Intensive care units?

    Directory of Open Access Journals (Sweden)

    Anasua Deb

    2016-05-01

    Full Text Available Background: Strict asepsis is necessary in operating theatres (OT and intensive care units (ICU as the patients undergo invasive procedures. The filters of contaminated air conditioning (AC units provide a niche for proliferation of fungi and production of fungal spores. Methods: The routine procedure for maintenance of sterile atmosphere in our hospital, i.e. fumigation and mopping walls with disinfectants often fail to address these fungal spores of the AC filters. We therefore carried out a surveillance of the ACs in ICUs and OTs to find the level of contamination with fungal spores and also to improvise on intervention strategies to tackle the problem. Over 3 months period, 34 ACs from 7 OTs and 2 ICUs were screened by taking 2 swabs from each AC which were then tested for the presence of fungal spores as per standard methods. Results: The contamination rate was 88.2% before fumigation and 76.9% after fumigation. The fungal spore contamination rate was reduced to 20% (1 out of 5 ACs after servicing of the ACs was done. Aspergillus spp. was the most common fungal isolate. Conclusion: Based on the observations, we recommend regular servicing of the ACs as well as wet mopping of the ducts with sporicidal solution at regular intervals. [Int J Res Med Sci 2016; 4(5.000: 1583-1589

  5. The Future of Information Operations in the United States Army

    Science.gov (United States)

    2007-01-01

    as Marketing Marketing tools and concepts could generate support for coalition military operations just as an advertiser promoting a commercial...military, the advanced application of marketing tools to leverage humanitarian assistance and public affairs within an Information Operations plan

  6. Influencing Tomorrow: A Study of Emerging Influence Techniques and Their Relevance to United States Information Operations

    Science.gov (United States)

    2015-06-12

    groups and governmental institutions; the possibility of economic loss directed at entrepreneurs; or the prospect of United States undue influence or... INFLUENCING TOMORROW: A STUDY OF EMERGING INFLUENCE TECHNIQUES AND THEIR RELEVANCE TO UNITED STATES INFORMATION OPERATIONS A...

  7. United States Military in Central Asia: Beyond Operation Enduring Freedom

    Science.gov (United States)

    2009-10-23

    Malinowski , advocacy director for Human Rights Watch, stated, “the United States is most effective in promoting liberty around the world when people...26 U.S. President, The National Security Strategy of the United States of America, page? 27 Thomas Malinowski , “Testimony

  8. Operational air quality forecast guidance for the United States

    Science.gov (United States)

    Stajner, Ivanka; Lee, Pius; Tong, Daniel; Pan, Li; McQueen, Jeff; Huang, Jinaping; Djalalova, Irina; Wilczak, James; Huang, Ho-Chun; Wang, Jun; Stein, Ariel; Upadhayay, Sikchya

    2016-04-01

    NOAA provides operational air quality predictions for ozone and wildfire smoke over the United States (U.S.) and predictions of airborne dust over the contiguous 48 states at http://airquality.weather.gov. These predictions are produced using U.S. Environmental Protection Agency (EPA) Community Model for Air Quality (CMAQ) and NOAA's HYSPLIT model (Stein et al., 2015) with meteorological inputs from the North American Mesoscale Forecast System (NAM). The current efforts focus on improving test predictions of fine particulate matter (PM2.5) from CMAQ. Emission inputs for ozone and PM2.5 predictions include inventory information from the U.S. EPA and recently added contributions of particulate matter from intermittent wildfires and windblown dust that rely on near real-time information. Current testing includes refinement of the vertical grid structure in CMAQ and inclusion of contributions of dust transport from global sources into the U.S. domain using the NEMS Global Aerosol Capability (NGAC). The addition of wildfire smoke and dust contributions in CMAQ reduced model underestimation of PM2.5 in summertime. Wintertime overestimation of PM2.5 was reduced by suppressing emissions of soil particles when the terrain is covered by snow or ice. Nevertheless, seasonal biases and biases in the diurnal cycle of PM2.5 are still substantial. Therefore, a new bias correction procedure based on an analog ensemble approach was introduced (Djalalova et al., 2015). It virtually eliminates biases in monthly means or in the diurnal cycle, but it also reduces day-to-day variability in PM2.5 predictions. Refinements to the bias correction procedure are being developed. Upgrades for the representation of wildfire smoke emissions within the domain and from global sources are in testing. Another area of active development includes approaches to scale emission inventories for nitrogen oxides in order to reproduce recent changes observed by the AirNow surface monitoring network and by

  9. Toeplitz Operators on Dirichlet-Type Space of Unit Ball

    Directory of Open Access Journals (Sweden)

    Jin Xia

    2014-01-01

    Full Text Available We construct a function u in L2Bn, dV which is unbounded on any neighborhood of each boundary point of Bn such that Toeplitz operator Tu is a Schatten p-class 0operator on Dirichlet-type space DBn, dV. Then, we discuss some algebraic properties of Toeplitz operators with radial symbols on the Dirichlet-type space DBn, dV. We determine when the product of two Toeplitz operators with radial symbols is a Toeplitz operator. We investigate the zero-product problem for several Toeplitz operators with radial symbols. Furthermore, the corresponding commuting problem of Toeplitz operators whose symbols are of the form ξku is studied, where k ∈ Zn, ξ ∈ ∂Bn, and u is a radial function.

  10. Toeplitz Operators with Quasihomogeneous Symbols on the Bergman Space of the Unit Ball

    Directory of Open Access Journals (Sweden)

    Bo Zhang

    2012-01-01

    symbols on the Bergman space of the unit ball equals a Toeplitz operator with quasihomogeneous symbols. We also characterize finite-rank semicommutators or commutators of two Toeplitz operators with quasihomogeneous symbols.

  11. Phase I remedial investigation report for the 300-FF-5 operable unit, Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-01-01

    The focus of this remedial investigation (RI) is the 300-FF-5 operable unit, one of five operable units associated with the 300 Area aggregate of the U.S. Department of Energy`s (DOE`s) Hanford Site. The 300-FF-5 operable unit is a groundwater operable unit beneath the 300-FF-1, 300-FF-2, and 300-FF-3 source operable units. This operable unit was designated to include all contamination detected in the groundwater and sediments below the water table that emanates from the 300-FF-1, 300-FF-2, and 300-FF-3 operable units (DOE-RL 1990a). In November 1989, the U.S. Environmental Protection Agency (EPA) placed the 300 Area on the National Priorities List (NPL) contained within Appendix B of the National Oil and Hazardous Substance Pollution Contingency Plan (NCP, 53 FR 51391 et seq.). The EPA took this action pursuant to their authority under the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA, 42 USC 9601 et seq.). The DOE Richland Operations Office (DOE-RL), the EPA and Washington Department of Ecology (Ecology) issued the Hanford Federal Facility Agreement and Consent Order (Tri-Party Agreement), in May 1989 (Ecology et al. 1992, Rev. 2). This agreement, among other matters, governs all CERCLA efforts at the Hanford Site. In June 1990, a remedial investigation/feasibility study (RI/FS) workplan for the 300-FF-5 operable unit was issued pursuant to the Tri-Party Agreement.

  12. 77 FR 29701 - Impact of Construction (Under a Combined License) of New Nuclear Power Plant Units on Operating...

    Science.gov (United States)

    2012-05-18

    ... a Combined License) of New Nuclear Power Plant Units on Operating Units at Multi-Unit Sites AGENCY... a COL intending to construct and operate new nuclear power plants (NPPs) on multi-unit sites to... Impacts of Construction (under a Combined License) of New Nuclear Power Plants on Operating Units at...

  13. 78 FR 16302 - Crystal River Unit 3 Nuclear Generating Plant, Application for Amendment to Facility Operating...

    Science.gov (United States)

    2013-03-14

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Crystal River Unit 3 Nuclear Generating Plant, Application for Amendment to Facility Operating... Operating License No. DPR-72 for the Crystal River Unit 3 Nuclear Generating Plant (CR-3), located in...

  14. Analysis Methods and Models for Small Unit Operations

    Science.gov (United States)

    2006-07-01

    methods are called for. TNO report I TNO-DV 2006 A228 9 /22 Efect Figure I Effect Based Operations framework. In practice, Figure 1 is useful when trying to...11, 111, IV, V Re-establishing communications Transport support (drivers, vehicles) Support to crowd and Riot Control (CRC) operations Support to... communicate opponent opponent intel gewonnen Verkennings- Reconnaissance Waarnemen terrein Observe terrain Inlichtingen over Gathered intel on patrouille

  15. MODELING OF HIGH STORAGE SHEET DEPOT WITH PLANT SIMULATION

    Directory of Open Access Journals (Sweden)

    Andrzej Jardzioch

    2013-03-01

    Full Text Available Manufacturing processes are becoming increasingly automated. Introduction of innovative solutions often necessitate processing very large number of signals from various devices. Correctness tests of the components configuration becomes a compiled operation requiring vast expenditure of time and knowledge. The models may be a mathematical reflection of the actual object. Many actions can be computer-assisted to varying degree. One example is construction of simulation models. These can also be simulation models developed in advanced software. The stages of creating a model may be purely random. This paper aims at a closer analysis of the simulation model based on the high storage sheet depot modeling using Plant Simulation software. The results of analysis can be used for optimization, but this stage is a separate issue.

  16. The case for a centralized repair depot for Space Shuttle

    Science.gov (United States)

    Enlow, R. D.

    1985-01-01

    The first priority of the NSTS program is to make the Space Shuttle system fully operational and cost effective in providing routine access to space. In support of this priority an integrated logistics support system was planned, structured and is being implemented to support a launch-on-time goal of 95 percent. In achieving a 95 percent spares 'fill rate' in an environment of small fleet size, highly unique and high cost assets, significant spares cost can be incurred. A major portion of these costs are for the additional spares required when repair or acquisition times are lengthy. This paper provides a fundamental analysis of the costs and other factors involved in the spare and repair process and provides an optimized cost and process solution for the Space Shuttle program - a centralized repair depot located at KSC.

  17. An Innovative Method for Dynamic Characterization of Fan FilterUnit Operation.

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Tengfang

    2006-12-21

    Fan filter units (FFU) are widely used to deliver re-circulated air while providing filtration control of particle concentration in controlled environments such as cleanrooms, minienvironments, and operating rooms in hospitals. The objective of this paper is to document an innovative method for characterizing operation and control of an individual fan filter unit within its operable conditions. Built upon the draft laboratory method previously published [1] , this paper presents an updated method including a testing procedure to characterize dynamic operation of fan filter units, i.e., steady-state operation conditions determined by varied control schemes, airflow rates, and pressure differential across the units. The parameters for dynamic characterization include total electric power demand, total pressure efficiency, airflow rate, pressure differential across fan filter units, and airflow uniformity.

  18. Microchannel apparatus comprising plural microchannels and methods of conducting unit operations

    Science.gov (United States)

    Wegeng, Robert S [Richland, WA; TeGrotenhuis, Ward E [Kennewick, WA; Whyatt, Greg A [West Richland, WA

    2009-03-10

    Microchannel apparatus comprising a header and plural flow microchannels is described in which orifices connect the header and the flow microchannels. The orifices constrict flow. The ratio of the cross-sectional area of each of the orifices to the cross-sectional area of the flow microchannels connected to the orifices is between 0.0005 and 0.1. Also described is microchannel apparatus for conducting unit operations in which a device comprises two arrays of microchannels, and a unit operation is conducted on a fluid as it passes through the first set of microchannels and into a header where a second unit operation is performed, and then the fluid stream passes into the second array of microchannels where the first unit operation is again performed. Methods of conducting unit operations in the apparatuses are also described.

  19. DoD Depot-Level Reparable Supply Chain Management: Process Effectiveness and Opportunities for Improvement

    Science.gov (United States)

    2014-01-01

    and reducing the time horizons of firm orders passed to the depots. It could start by shifting all production planning to six-month intervals. After...degree on repair process flow time, and, in some services, retrograde time. This reduces the amount of inventory the closed-loop system needs to meet...We should also note that a disruption in the retrograde pipeline from Iraq to Kuwait and then back to the United States also hampered Figure 4.5

  20. Proposed Continental Operations Range. United States Air Force.

    Science.gov (United States)

    1974-06-01

    Fallon, Battle Motutain, Francis Peak, and Cedar City. Other COR non-participating ertities to be linked to COR Central to promote cooperation in...qualities worth retain’ng: friendliness, and toleration of privacy. "So it is a valid fear that some of thebe valued traditions will be lost with the...by sheep during the winter months from November 1 to April 30. (;razing units In the Battle Mountain Grazing district of the BL, in the northern part

  1. United States Air Force Role in Mass Atrocity Response Operations

    Science.gov (United States)

    2012-05-17

    through the lens of their own perspective. They cannot view the world objectively because of their own preconceptions : history, prejudices, ideology...initial stages of the genocide. Similarly, the RC-135’s ability to detect and locate those stations would provide the perfect target for strikes having...all levels. Air Force unit exercises would integrate air power, focusing on those specific tasks required in a MARO. These training exercises , in

  2. On Point: The United States Army in Operation Iraqi Freedom

    Science.gov (United States)

    2004-01-01

    Captain Matthew Paul and Sergeant Jose Adorno , Task Force 2-7 IN mortar platoon, walked down the road the unit had used earlier to enter the airport...than 10 seconds later, the ground rumbled with the sound of approaching armor once again, and Captain Paul and Sergeant Adorno turned to move out of...road; Sergeant Adorno sprinted off to the right. Winding through the trees and bushes screening Four Corners, he was back with the mortar platoon in

  3. Parallel Operation Characteristics Analysis of Sewage Source Heat Pump Units in Winter

    Institute of Scientific and Technical Information of China (English)

    庄兆意; 张承虎; 王海燕; 孙德兴

    2010-01-01

    Sewage source heat pump unit operates under partial load most of the time, and study on the law of coefficient of performance (COP) of the unit varying with load ratio can provide basis for the heat pump units running in high efficiency. A mathematical model determining COP, evaporation temperature and condensation temperature of a single unit was proposed. Under the condition of uniform load distribution, the model was established according to different ways of bearing partial load with the same type multi...

  4. United Nations Operations: Who Should be in Charge?

    Science.gov (United States)

    1994-04-01

    Cold War; Panama, Iraq, and the New World Order, in RIGHT V. MIGHT, supra note 16, at 109, 128; and HANS KELSON, THE LAW OF THE UNITED NATIONS 928...interpretation would also appear to resolve Kelsen’s dilemma (see KELSEN , supra note 35, at 935) with respect to the Korean conflict. Kelsen argues the Security...and Scheffer, supra note 35, at 131. 45. See D. J. HARRIS, CASES AND MATERIAL ON INTERNATIONAL LAW 681 (4th ed. 1991); KELSEN , supra note 35, at 756

  5. Selecting Foreign Languages for United States Army Special Operations Forces

    Science.gov (United States)

    2006-06-16

    Portugal 170,000,000 7 RUSSIAN [RUS] Russia 170,000,000 8 JAPANESE [JPN] Japan 125,000,000 9 GERMAN, STANDARD [GER] Germany 98,000,000 10 CHINESE, WU...took place (Birtle 2004, Ch 2). Operations in Mexico, Cuba, Russia , and the Philippines are examples of US expeditionary forces deployed to areas...Department of the Army civilians, and retirees. The programs available are free of charge and are for either beginners or people seeking to increase or

  6. Operational Encirclements: Can the United States Military Decisively Follow Through?

    Science.gov (United States)

    2009-05-21

    friction that trickles down onto the battlefield. The European theatre during World War II was no different. The failure of American, and British...American and their Allied partners would continue to experience the ill-effects of it right up until the end of the war in the European theatre ...on Friday 27 March 2009 about Operation Anaconda. I used some information from our conversation. The following is verbatim from my monograph, "A

  7. The United States Army Operating Concept, 2016-2028

    Science.gov (United States)

    2010-08-19

    retrograde operations. f. Theater armies may also include a medical command for deployment support that provides health services to Army and other...tenets of jus in bello ,120 discrimination (between combatants and noncombatants), and proportionality in the use of force,121 measured against the...Barracks, PA, 19. (Used with permission.) 119 Biddle, 9. 120 Jus in bello , translated as justice in war, are agreements defining limits on acceptable

  8. Tactical Unit Data and Decision Requirements for Urban Operations

    Science.gov (United States)

    2008-10-01

    decision requirements useful in urban operations. DISCLAIMER: The contents of this report are not to be used for advertising , publication, or...Building Function Verify mosque and identify possi- ble schools or meeting places Identify types of cinema (stage/theatre) or other similar nearby...Determine mosque and residen- tial floor plans Interior layout of cinema and high-rises Layout of power control facilities Improved Dismounted & Mounted

  9. Biota of the 300-FF-1 operable unit. [Westinghouse Hanford Company

    Energy Technology Data Exchange (ETDEWEB)

    Rickard, W.H. Jr.; Fitzner, R.E.; Brandt, C.A.

    1990-10-01

    This report summarizes Task 5a-2 of the Phase I Remedial Investigation -- Operable Unit Characterization of the 300-FF-1 Operable Unit on the Hanford Site, near Richland, Washington. The ultimate goal of Phase I is to determine the nature and extent of the threat to public health and the environment from releases of hazardous substances from the operable unit. The purpose of Task 5a-2 was to determine what species inhabit the 300-FF-1 Operable Unit and how they use the unit. The focus is on those species listed as endangered or threatened, those that are economically important, or those that constitute significant components of the human food chain. 39 refs., 5 figs., 5 tabs.

  10. Fatty acid composition of fat depots in wintering Canada geese

    Science.gov (United States)

    Austin, J.E.

    1993-01-01

    I determined the fatty acid composition of subcutaneous, abdominal, visceral, and leg saddle depots in adult female Canada Geese (Branta canadensis) wintering in north-central Missouri during October 1984-March 1985. Mean levels of C14:0, C16:0, C16:1, C18:0, C18:1, C18:2, and C18:3 generally were highest in the subcutaneous and abdominal depots. The ratio of saturated to unsaturated fats was highest in the leg saddle depot and lowest in the abdominal depot. I also assessed the differences among sexes, seasons, and years in fatty acid composition of abdominal fat depots in adult geese collected during October-March, 1985-1987. Adult females had consistently higher levels of C14:0 in abdominal depots than males. Fatty acid composition of the abdominal depot differed among years but not by season. In the abdominal depot, C14:0, C16:0, C16:1, and C18:1 were higher in 1986-1987 compared with the previous two years, whereas C18:3 was highest in 1984-1985. Differences among years reflected changes in winter diet. Fatty acids of wintering geese were similar to those previously found in breeding Canada Geese.

  11. Operational Optimization of Large-Scale Parallel-Unit SWRO Desalination Plant Using Differential Evolution Algorithm

    Directory of Open Access Journals (Sweden)

    Jian Wang

    2014-01-01

    Full Text Available A large-scale parallel-unit seawater reverse osmosis desalination plant contains many reverse osmosis (RO units. If the operating conditions change, these RO units will not work at the optimal design points which are computed before the plant is built. The operational optimization problem (OOP of the plant is to find out a scheduling of operation to minimize the total running cost when the change happens. In this paper, the OOP is modelled as a mixed-integer nonlinear programming problem. A two-stage differential evolution algorithm is proposed to solve this OOP. Experimental results show that the proposed method is satisfactory in solution quality.

  12. Dot Enumeration Perceptual Organization Task (DEPOT): evidence for a short-term visual memory deficit in schizophrenia.

    Science.gov (United States)

    Rabinowicz, E F; Opler, L A; Owen, D R; Knight, R A

    1996-08-01

    The Dot Enumeration Perceptual Organization Task (DEPOT) evaluates the validity of 2 specific competing cognitive models of early input dysfunction in schizophrenic individuals: a primary Stage 1, sensory store, perceptual organization deficit vs. a Stage 2, short-term visual memory (STVM) deficit. DEPOT was also designed to assess the hypothesis that schizophrenic individuals tend to perform poorly on all cognitive tasks. In DEPOT both number and form judgments are made about the same dot patterns. A response delay manipulation assesses the persistence and operation of STVM. The study included 41 psychotic inpatients (8 with acute and 16 with chronic schizophrenia and 7 with bipolar and 10 with nonbipolar affective disorder) and 38 controls (22 college students and 16 hospital personnel). Although the pattern of results was consistent with neither the Stage 1 deficit nor the general deficit hypotheses, a Stage 2, STVM deficit hypothesis could account parsimoniously for the data.

  13. Hospital markup and operation outcomes in the United States.

    Science.gov (United States)

    Gani, Faiz; Ejaz, Aslam; Makary, Martin A; Pawlik, Timothy M

    2016-07-01

    Although the price hospitals charge for operations has broad financial implications, hospital pricing is not subject to regulation. We sought to characterize national variation in hospital price markup for major cardiothoracic and gastrointestinal operations and to evaluate perioperative outcomes of hospitals relative to hospital price markup. All hospitals in which a patient underwent a cardiothoracic or gastrointestinal procedure were identified using the Nationwide Inpatient Sample for 2012. Markup ratios (ratio of charges to costs) for the total cost of hospitalization were compared across hospitals. Risk-adjusted morbidity, failure-to-rescue, and mortality were calculated using multivariable, hierarchical logistic regression. Among the 3,498 hospitals identified, markup ratios ranged from 0.5-12.2, with a median markup ratio of 2.8 (interquartile range 2.7-3.9). For the 888 hospitals with extreme markup (greatest markup ratio quartile: markup ratio >3.9), the median markup ratio was 4.9 (interquartile range 4.3-6.0), with 10% of these hospitals billing more than 7 times the Medicare-allowable costs (markup ratio ≥7.25). Extreme markup hospitals were more often large (46.3% vs 33.8%, P markup ratio compared with 19.3% (n = 452) and 6.8% (n = 35) of nonprofit and government hospitals, respectively. Perioperative morbidity (32.7% vs 26.4%, P markup hospitals. There is wide variation in hospital markup for cardiothoracic and gastrointestinal procedures, with approximately a quarter of hospital charges being 4 times greater than the actual cost of hospitalization. Hospitals with an extreme markup had greater perioperative morbidity. Copyright © 2016 Elsevier Inc. All rights reserved.

  14. Analysis of Fukushima unit 2 accident considering the operating conditions of RCIC system

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Sung Il, E-mail: sikim@kaeri.re.kr; Park, Jong Hwa; Ha, Kwang Soon; Cho, Song-Won; Song, JinHo

    2016-03-15

    Highlights: • Fukushima unit 2 accident was analyzed using MELCOR 1.8.6. • RCIC operating conditions were assumed and best case was selected. • Effect of RCIC operating condition on accident scenario was found. - Abstract: A severe accident in Fukushima occurred on March 11, 2011 and units 1, 2 and 3 were damaged severely. A tsunami following an earthquake made the supply of electricity power stop, and the safety systems, which use AC or DC power in plants could not operate properly. It is supposed that the degree of core degradation of unit 2 is less serious than in the other plants, and it was estimated that the operation of reactor core isolation cooling (RCIC) system at the initial stage of the accident minimized the core damage through decay heat removal. Although the operating conditions of the RCIC system are not known clearly, it can be important to analyze the accident scenario of unit 2. In this study, best case of the Fukushima unit 2 accident was presented considering the operating conditions of the RCIC system. The effects of operating condition on core degradation and fission product release rate to environment were also examined. In addition, importance of torus room flooding level in the accident analysis was discussed. MELCOR 1.8.6 was used in this research, and the geometries of plant and operating conditions of safety system were obtained from TEPCO through OECD/NEA BSAF Project.

  15. Multi-unit Operations in Non-Nuclear Systems: Lessons Learned for Small Modular Reactors

    Energy Technology Data Exchange (ETDEWEB)

    OHara J. M.; Higgins, J.; DAgostino, A.

    2012-01-17

    The nuclear-power community has reached the stage of proposing advanced reactor designs to support power generation for decades to come. Small modular reactors (SMRs) are one approach to meet these energy needs. While the power output of individual reactor modules is relatively small, they can be grouped to produce reactor sites with different outputs. Also, they can be designed to generate hydrogen, or to process heat. Many characteristics of SMRs are quite different from those of current plants and may be operated quite differently. One difference is that multiple units may be operated by a single crew (or a single operator) from one control room. The U.S. Nuclear Regulatory Commission (NRC) is examining the human factors engineering (HFE) aspects of SMRs to support licensing reviews. While we reviewed information on SMR designs to obtain information, the designs are not completed and all of the design and operational information is not yet available. Nor is there information on multi-unit operations as envisioned for SMRs available in operating experience. Thus, to gain a better understanding of multi-unit operations we sought the lesson learned from non-nuclear systems that have experience in multi-unit operations, specifically refineries, unmanned aerial vehicles and tele-intensive care units. In this paper we report the lessons learned from these systems and the implications for SMRs.

  16. Routine Operation of the Envirodish Unit at the Engineering School of the University of Seville

    Energy Technology Data Exchange (ETDEWEB)

    Silva Perez, M. A.; Ruiz Hernandez, V.; Garcia Granados, F. J.; Lillo Bravo, I.

    2006-07-01

    A 10 kWe Parabolic Dish Stirling engine system was installed at the Seville Engineering School in early 2004. This system is one of the Country Reference Units of the EnviroDish project, consisting in the installation and operation of several such units, based on the EuroDish system, in different countries aimed to gathering reliable O and M data that help to improve and fine-tune the technology. The Seville Country Reference Unit is connected to the grid under the Special Regime for power generation, which establishes credits to power generation based on renewable energy sources. The Seville Country Reference Unit has been in operation since March 2004, accumulating 1671 operation hours and 7.8 MWh of electricity production until August 2005. This paper summarizes the results of 18 months operation, with emphasis on O and M aspects and lessons learned during this period. (Author)

  17. Technology used to operate the 300-MW power unit topped with a GTE-110 gas turbine

    Science.gov (United States)

    Berezinets, P. A.; Doverman, G. I.

    2010-09-01

    Results obtained from mathematical simulation of operations for starting the 300-MW power unit topped with a GTE-110 gas turbine installed at the GRES-24 district power station of OAO OGK-6 wholesale power-generating company are described. It is shown that operations on speeding up the steam turbine from a cold state to its idle running mode can be carried out solely by using the heat of exhaust gases from the gas turbine unit without supplying fuel to the boiler.

  18. Modification of Elementary Operational Linear Chains in Compositional Control Unit with Code Sharing

    OpenAIRE

    Aleksander, A.; Larysa, A.; Aleksander, N.

    2009-01-01

    The new design method for compositional microprogram control units with code sharing and elementarization of operational linear chains is proposed. The method targets on reduction in the number of LUT-elements in the combinational part of control unit. Some additional control microinstructions containing codes of the classes of pseudoequivalent chains are used for operational linear chains modification. Proposed method is illustrated by an example. Most desirable GSA characteristics for using...

  19. 2005 Annual Operations Report for INTEC Operable Unit 3-13, Group 1, Tank Farm Interim Action

    Energy Technology Data Exchange (ETDEWEB)

    D. Shanklin

    2006-07-19

    This annual operations report describes the requirements followed and activities conducted to inspect, monitor, and maintain the items installed during performance of the Waste Area Group 3, Operable Unit 3-13, Group 1, Tank Farm Interim Action, at the Idaho Nuclear Technology and Engineering Center. This report describes inspection and monitoring activities fro the surface-sealed areas within the tank farm, concrete-lined ditches and culverts in and around the tank farm, the lift station, and the lined evaporation pond. These activities are intended to assure that the interim action is functioning adequately to meet the objectives stated in the Operable Unit 3-13, Record of Decision for the Group 1, Tank Farm Interim Action, (DOE/ID-10660) and as amended by the agreement to resolve dispute, which was effective in February 2003.

  20. 2005 Annual Operations Report for INTEC Operable Unit 3-13, Group 1, Tank Farm Interim Action

    Energy Technology Data Exchange (ETDEWEB)

    D. Shanklin

    2006-07-19

    This annual operations report describes the requirements followed and activities conducted to inspect, monitor, and maintain the items installed during performance of the Waste Area Group 3, Operable Unit 3-13, Group 1, Tank Farm Interim Action, at the Idaho Nuclear Technology and Engineering Center. This report describes inspection and monitoring activities fro the surface-sealed areas within the tank farm, concrete-lined ditches and culverts in and around the tank farm, the lift station, and the lined evaporation pond. These activities are intended to assure that the interim action is functioning adequately to meet the objectives stated in the Operable Unit 3-13, Record of Decision for the Group 1, Tank Farm Interim Action, (DOE/ID-10660) and as amended by the agreement to resolve dispute, which was effective in February 2003.

  1. 76 FR 66051 - Availability of the Fiscal Year 2010 United States Special Operations Command (USSOCOM) Inventory...

    Science.gov (United States)

    2011-10-25

    ... of the Secretary Availability of the Fiscal Year 2010 United States Special Operations Command... 2330a of Title 10 United States Code as amended by the National Defense Authorization Act for Fiscal..., Defense Procurement and Acquisition Policy, Office of Strategic Sourcing (DPAP/SS) will make available to...

  2. 77 FR 38274 - Availability of the Fiscal Year 2011 United States Special Operations Command (USSOCOM) Inventory...

    Science.gov (United States)

    2012-06-27

    ... of the Secretary Availability of the Fiscal Year 2011 United States Special Operations Command... 2330a of Title 10, United States Code as amended by the National Defense Authorization Act for Fiscal... Acquisition Policy, Office of Strategic Sourcing (DPAP/SS) will make available to the public the first...

  3. United States Special Operations Command Strategic Issues for the Long War

    Science.gov (United States)

    2006-03-15

    for USSOCOM’s campaign plan. UNITED STATES SPECIAL OPERATIONS COMMAND STRATEGIC ISSUES FOR THE LONG WAR World order is more fundamental and primordial ... Soup to Nuts: Understanding the Elements of the Strategy The United States is a big, lumbering, pluralistic, affluent, liberal, democratic

  4. Understanding of empty container movement: A study on a bottleneck at an off-dock depot

    Science.gov (United States)

    Zain, Rosmaizura Mohd; Rahman, Mohd Nizam Ab; Nopiah, Zulkifli Mohd; Saibani, Nizaroyani

    2014-09-01

    Port not only function as connections between marine and land transportation but also as core business areas. In a port terminal, available space is limited, but the influx of container is growing. The off-dock depot is one of the key supply chain players that hold empty containers in the inventory. Therefore, this paper aims to identify the main factors of bottlenecks or congestion that hinder the rapid movement of empty containers from the off-dock depot to the customers. Thirty interviews were conducted with individuals who are key players in the container supply chain. The data were analyzed using Atlas.ti software and the analytic hierarchy process to rank the priority factors of bottlenecks. Findings show that several pertinent factors act as barriers to the key players in the container movement in the day-to-day operations. In future studies, strategies to overcome fragmentation in the container supply chain and logistics must be determined.

  5. Effect of RCIC Operating Conditions on the Accident Scenario in Fukushima Unit 2

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Sung Il; Park, Jong Hwa; Ha, Kwang Soon [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-10-15

    This study was conducted by using MELCOR 1.8.6. Fukushima unit 2 accident was analyzed using MELCOR in this study, and best estimate scenario with considering RCIC operating conditions was presented. Researches on the boiling water reactor (BWR) plant with reactor core isolation cooling (RCIC) system have been conducted. Research on the RCIC operation in Fukushima unit 2 was also conducted by Sandia National Laboratory. MELCOR analysis of the Fukushima unit 2 accident was conducted in the report and energy balance in wetwell was described by considering RCIC operation. However, the effect of RCIC operation condition on the accident scenario has not been studied. The operating conditions of RCIC system affect the pressures in wetwell and drywell, and the high pressure can make leakage path of fission product from PCV to reactor building. Thus it can be directly related with the amount of fission product which released to environment. In this study, severe accident on Fukushima unit 2 was analyzed considering the operating condition of RCIC system, and best estimated scenario was presented. In addition, the effect of RCIC turbine efficiency on the accident progression was examined. Energy balance in suppression chamber was also considered with discussion on the effect of torus room flooding level. It was found that the operating condition of RCIC turbine not only affects the variation of drywell pressure but also the amount of released fission products to environment. It was also confirmed that the RCIC turbine efficiency in the accident would be less than normal operating condition.

  6. Feasibility study report for the 200-BP-1 operable unit. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    1994-01-01

    This feasibility study (FS) examines a range of alternatives and provides recommendations for selecting a preferred altemative for remediating contamination at the 200-BP-1 operable unit. The 200-BP-1 operable unit is located in the center of the Hanford Site along the northern boundary of the 200 East Area. The 241-BY Tank Farm is located immediately to the south of the operable unit. 200-BP-1 is a source operable unit with contaminated soils associated primarily with nine inactive cribs (known as the 216-B cribs). These cribs were used for disposal of low-level radioactive liquid waste from U Plant uranium recovery operations, and waste storage tank condensate from the adjacent 241-BY Tank Farm. The cribs used for disposal of U Plant waste were in operation from 1955--1965, and the cribs used for disposal of tank condensate were in operation from 1965-1975. In addition to the cribs, four unplanned releases of radioactive materials have occurred within the operable unit. Contaminated surface soils associated with the unplanned releases have been consolidated over the cribs and covered with clean soil to reduce contaminant migration and exposure. Discharge of wastes to the cribs has resulted in soil and groundwater contamination. The groundwater is being addressed as part of the 200 East Aggregate Area groundwater operable unit. Contaminated soils at the site can be categorized by the types of contaminants, their distribution in the soil column, and the risk posed by the various potential exposure pathways. Below the clean soil cover, the near surface soils contain low-:levels of contamination with cesium-137, radium-226, strontium-90, thorium-228 and uranium. The lifetime incremental cancer risk associated with these soils if they were exposed at the surface is 9 {times} 10{sup 5}.

  7. DEPOT database: Reference manual and user's guide

    Energy Technology Data Exchange (ETDEWEB)

    Clancey, P.; Logg, C.

    1991-03-01

    DEPOT has been developed to provide tracking for the Stanford Linear Collider (SLC) control system equipment. For each piece of equipment entered into the database, complete location, service, maintenance, modification, certification, and radiation exposure histories can be maintained. To facilitate data entry accuracy, efficiency, and consistency, barcoding technology has been used extensively. DEPOT has been an important tool in improving the reliability of the microsystems controlling SLC. This document describes the components of the DEPOT database, the elements in the database records, and the use of the supporting programs for entering data, searching the database, and producing reports from the information.

  8. Development and Use of a Web Site with Multimedia Contents as a Complement to Traditional Unit Operations Courses

    Science.gov (United States)

    Tapia, Cristian; Muller, Mauricio; Sapag-Hagar, Jaime; Valenzuela, Fernando; Basualto, Carlos; Abugoch, Lilian

    2005-01-01

    The Unit Operations Laboratory offers 2 courses in unit operations. One is a 2-semester course for chemistry and food engineering students that is more demanding because it considers more unit operations and places more emphasis on solving exercises. The other is a 1-semester course for chemistry and pharmacy students that considers fewer unit…

  9. Results of toxicity tests and chemical analyses conducted on sediments collected from the TNX Outfall Delta Operable Unit, July 1999

    Energy Technology Data Exchange (ETDEWEB)

    Specht, W.L.

    2000-02-11

    In order to provide unit specific toxicity data that will be used to address critical uncertainty in the ecological risk assessment (ERA) for the TNX Outfall Delta Operable Unit (TNXOD OU), sediments were collected from eight locations in the Inner Swamp portion of the operable unit and two unit specific background locations. These samples were analyzed for total mercury, total uranium, and sediment toxicity.

  10. Locating Depots for Capacitated Vehicle Routing

    DEFF Research Database (Denmark)

    Gørtz, Inge Li; Nagarajan, Viswanath

    2016-01-01

    We study a location-routing problem in the context of capacitated vehicle routing. The input to the k-location capacitated vehicle routing problem (k-LocVRP) consists of a set of demand locations in a metric space and a fleet of k identical vehicles, each of capacity Q. The objective is to locate k...... depots, one for each vehicle, and compute routes for the vehicles so that all demands are satisfied and the total cost is minimized. Our main result is a constant-factor approximation algorithm for k-LocVRP. In obtaining this result, we introduce a common generalization of the k-median and minimum...... spanning tree problems (called k median forest), which might be of independent interest. We give a local-search based (3+ε)-approximation algorithm for k median forest, which leads to a (12+ε)-approximation algorithm for k-LocVRP, for any constant ε>0....

  11. United States Department of Energy, Nevada Operations Office, completion report Operation KLAXON, Fiscal Year 1993

    Energy Technology Data Exchange (ETDEWEB)

    1994-06-01

    The U.S. Department of Energy, Nevada Operations Office (DOE/NV), Completion Report provides a summary of activities conducted at the Nevada Test Site (NTS) between October 1, 1992, and September 30, 1993, associated with Operation KLAXON. (In the past, each annual Completion Report dealt with a series of underground nuclear detonations; however, because no nuclear tests were conducted during FY 1993, this Report summarizes continuing nonnuclear and nuclear test readiness activities at the NTS sponsored by DOE/NV.) The report serves as a reference for those involved with the planning and execution of Operation KLAXON and also serves as a planning guide for future operations. Information in the report covers the logistics and management of activities. Scientific information and data associated with NTS activities are presented in technical documents published by participating agencies. In September 1992, Congress legislated a nine-month moratorium on the testing of nuclear weapons. The bill also provided for a resumption of testing (with no more than five tests per year, or a total of 15 during the next three years) in July 1993, and mandated an end to nuclear testing, entirely, by 1996. President Bush signed the bill into law in October 1992.

  12. Abarelix: abarelix-depot-F, abarelix-depot-M, abarelix-L, PPI 149, R 3827.

    Science.gov (United States)

    2003-01-01

    Abarelix [Abarelix-Depot-F, Abarelix-Depot-M, Abarelix-L, PPI 149, R 3827, Plenaxis] is a peptide consisting of natural and artificial amino acids. In females, abarelix is an estrogen production antagonist with potential for the treatment of breast cancer, endometriosis and other reproductive hormone diseases. In males it is a testosterone production antagonist and has potential as hormonal therapy of prostate cancer. Depot formulations of abarelix (abarelix-depot-M and abarelix-depot-F) are being developed for hormonally responsive prostate cancer and endometriosis, respectively. Clinical development of the depot formulations is currently being conducted by Praecis Pharmaceuticals, the originators of the agent. A non-depot formulation, abarelix-L, was also being conducted for prostate gland volume reduction. Praecis Pharmaceuticals has entered into a number of licensing agreements covering abarelix. However, all agreements have since been terminated leaving Praecis to develop and commercialise the agent on its own. The terminated agreements include an agreement between Praecis and Roche for the commercialisation of abarelix in the US. This agreement was terminated in November 1998. Praecis Pharmaceuticals also entered into a collaborative agreement with Amgen in March 1999, whereby the companies would develop abarelix and Amgen would commercialise the drug in the US, Canada, Australia, Asia and several secondary markets. However, in September 2001, Praecis and Amgen announced that they were terminating the agreement for all indications. Praecis stated at the time that it remained committed to developing abarelix for both prostate cancer and endometriosis. Amgen had submitted 'Lotestrol' to the US Patent and Trademarks Office as a possible tradename for abarelix-depot-M. Lotestrol may also have been under consideration as a tradename for abarelix-depot-F. Praecis had also sold European, African, Latin American and Middle Eastern rights to abarelix to Sanofi

  13. Performance Gains of Propellant Management Devices for Liquid Hydrogen Depots

    Science.gov (United States)

    Hartwig, Jason W.; McQuillen, John B.; Chato, David J.

    2013-01-01

    This paper presents background, experimental design, and preliminary experimental results for the liquid hydrogen bubble point tests conducted at the Cryogenic Components Cell 7 facility at the NASA Glenn Research Center in Cleveland, Ohio. The purpose of the test series was to investigate the parameters that affect liquid acquisition device (LAD) performance in a liquid hydrogen (LH2) propellant tank, to mitigate risk in the final design of the LAD for the Cryogenic Propellant Storage and Transfer Technology Demonstration Mission, and to provide insight into optimal LAD operation for future LH2 depots. Preliminary test results show an increase in performance and screen retention over the low reference LH2 bubble point value for a 325 2300 screen in three separate ways, thus improving fundamental LH2 LAD performance. By using a finer mesh screen, operating at a colder liquid temperature, and pressurizing with a noncondensible pressurant gas, a significant increase in margin is achieved in bubble point pressure for LH2 screen channel LADs.

  14. The Applied Meteorology Unit: Nineteen Years Successfully Transitioning Research Into Operations for America's Space Program

    Science.gov (United States)

    Madura, John T.; Bauman, William H., III; Merceret, Francis J.; Roeder, William P.; Brody, Frank C.; Hagemeyer, Bartlett C.

    2011-01-01

    The Applied Meteorology Unit (AMU) provides technology development and transition services to improve operational weather support to America's space program . The AMU was founded in 1991 and operates under a triagency Memorandum of Understanding (MOU) between the National Aeronautics and Space Administration (NASA), the United States Air Force (USAF) and the National Weather Service (NWS) (Ernst and Merceret, 1995). It is colocated with the 45th Weather Squadron (45WS) at Cape Canaveral Air Force Station (CCAFS) and funded by the Space Shuttle Program . Its primary customers are the 45WS, the Spaceflight Meteorology Group (SMG) operated for NASA by the NWS at the Johnson Space Center (JSC) in Houston, TX, and the NWS forecast office in Melbourne, FL (MLB). The gap between research and operations is well known. All too frequently, the process of transitioning research to operations fails for various reasons. The mission of the AMU is in essence to bridge this gap for America's space program.

  15. Expandable Cryogenic Tankage for On Orbit Depot Storage Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The proposed expandable depot storage tanks would make it possible to have an on-orbit tank larger in volume than any existing or planned launch vehicles. The size...

  16. Radiological Final Status Survey of the Hammond Depot, Hammond, Indiana

    Energy Technology Data Exchange (ETDEWEB)

    T.J. Vitkus

    2008-04-07

    ORISE conducted extensive scoping, characterization, and final status surveys of land areas and structures at the DNSC’s Hammond Depot located in Hammond, Indiana in multiple phases during 2005, 2006 and 2007.

  17. SERDP-ESTCP Depot Cd/Chromate Replacement Initiative

    Science.gov (United States)

    2014-11-18

    ESTCP SERDP Environmental Technology Development Process Office of the Deputy Under Secretary of Defense - Installations and Environment 4...SERDP-ESTCP Depot Cd/ Chromate Replacement Initiative Robin Nissan Weapons Systems and Platforms Program Manager ASETSDefense 18 November 2014...NOV 2014 2. REPORT TYPE 3. DATES COVERED 00-00-2014 to 00-00-2014 4. TITLE AND SUBTITLE SERDP-ESTCP Depot Cd/ Chromate Replacement Initiative 5a

  18. Man-hour Estimation Model based on Standard Operation Unit for Flexible Manufacturing System

    Directory of Open Access Journals (Sweden)

    Ye Zhenggeng

    2017-01-01

    Full Text Available In flexible manufacturing system, the estimation of man-hour is a difficult problem because of its production-diversity. To explore a more effective method, this paper tried to estimate man-hour from the perspective of operation`s character by establishing standard operation unit (SOU in this paper. A method of parameterizing the SOU is proposed, and a new man-hour estimation model is established on the basis of SOU. At last, this paper verified the effectiveness of this method by the operation of large-scale welding parts.

  19. Development of in-situ product removal strategies in biocatalysis applying scaled-down unit operations

    DEFF Research Database (Denmark)

    Heintz, Søren; Börner, Tim; Ringborg, Rolf Hoffmeyer

    2017-01-01

    An experimental platform based on scaled-down unit operations combined in a plug-and-play manner enables easy and highly flexible testing of advanced biocatalytic process options such as in-situ product removal (ISPR) process strategies. In such a platform it is possible to compartmentalize...... different process steps while operating it as a combined system, giving the possibility to test and characterize the performance of novel process concepts and biocatalysts with minimal influence of inhibitory products. Here the capabilities of performing process development by applying scaled-down unit......-automatically characterize ω-transaminases in a scaled-down packed-bed reactor (PBR) module, showing MPPA as a strong inhibitor. To overcome the inhibition, a two-step liquid-liquid extraction (LLE) ISPR concept was tested using scaled-down unit operations combined in a plug-and-play manner. Through the tested ISPR concept...

  20. Operable Unit 3-13, Group 3, Other Surface Soils (Phase I) Remedial Action Report

    Energy Technology Data Exchange (ETDEWEB)

    L. Davison

    2007-07-31

    This Remedial Action Report summarizes activities undertaken to remediate the Operable Unit 3-13, Group 3, Other Surface Soils, Phase I sites at the Idaho Nuclear Technology and Engineering Center at the Idaho National Laboratory Site. The 10 sites addressed in this report were defined in the Operable Unit 3-13 Record of Decision and subsequent implementing documents. This report concludes that remediation requirements and cleanup goals established for these 10 sites have been accomplished and are hereafter considered No Action or No Further Action sites.

  1. Qualitative risk assessment for the 100-KR-4 groundwater operable unit

    Energy Technology Data Exchange (ETDEWEB)

    Biggerstaff, R.L.

    1994-06-30

    This report provides the qualitative risk assessment (QRA) for the 100-KR-4 groundwater operable unit at the US Department of Energy`s (DOE) Hanford Site in southeastern Washington State. The extent of the groundwater beneath the 100 K Area is defined in the Remedial Investigation/Feasibility Study Work Plan for the 100-KR-4 Operable Unit (DOE-RL 1992a). The QRA is an evaluation or risk using a limited amount of data and a predefined set of human and environmental exposure scenarios and is not intended to replace or be a substitute for a baseline risk assessment.

  2. Operable Unit 3-13, Group 7, SFE-20 Hot Waste Tank System Remedial Action Request

    Energy Technology Data Exchange (ETDEWEB)

    L. Davison

    2009-06-30

    This Remedial Action Report summarizes activities undertaken to remediate the Operable Unit 3-13, Group 7, SFE-20 Hot Waste Tank System at the Idaho Nuclear Technology and Engineering Center at the Idaho National Laboratory Site. The site addressed in this report was defined in the Operable Unit 3-13 Record of Decision and subsequent implementing documents. This report concludes that remediation requirements and cleanup goals established for the site have been accomplished and is hereafter considered a No Further Action site.

  3. Operable Unit 3-13, Group 7, SFE-20 Hot Waste Tank System Remedial Action Report

    Energy Technology Data Exchange (ETDEWEB)

    Lee Davison

    2009-06-30

    This Remedial Action Report summarizes activities undertaken to remediate the Operable Unit 3-13, Group 7, SFE-20 Hot Waste Tank System at the Idaho Nuclear Technology and Engineering Center at the Idaho National Laboratory Site. The site addressed in this report was defined in the Operable Unit 3-13 Record of Decision and subsequent implementing documents. This report concludes that remediation requirements and cleanup goals established for the site have been accomplished and is hereafter considered a No Further Action site.

  4. Phase 1 remedial investigation report for 200-BP-1 operable unit. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    1993-09-01

    The US Department of Energy (DOE) Hanford Site, in Washington State is organized into numerically designated operational areas including the 100, 200, 300, 400, 600, and 1100 Areas. The US Environmental Protection Agency (EPA), in November 1989 included the 200 Areas of the Hanford Site on the National Priority List (NPL) under the Comprehensive Environmental Response, Compensation and Liability Act of 1980 (CERCLA). Inclusion on the NPL initiated the remedial investigation (RD process for the 200-BP-1 operable unit. These efforts are being addressed through the Hanford Federal Facility Agreement and Consent Order (Ecology et al. 1989) which was negotiated and approved by the DOE, the EPA, and the State of Washington Department of Ecology (Ecology) in May 1989. This agreement, known as the Tri-Party Agreement, governs all CERCLA efforts at Hanford. In March of 1990, the Department of Energy, Richland Operations (DOE-RL) issued a Remedial Investigation/Feasibility Study (RI/FS) work plan (DOE-RL 1990a) for the 200-BP-1 operable unit. The work plan initiated the first phase of site characterization activities associated with the 200-BP-1 operable unit. The purpose of the 200-BP-1 operable unit RI is to gather and develop the necessary information to adequately understand the risks to human health and the environment posed by the site and to support the development and analysis of remedial alternatives during the FS. The RI analysis will, in turn, be used by Tri-Party Agreement signatories to make a risk-management-based selection of remedies for the releases of hazardous substances that have occurred from the 200-BP-1 operable unit.

  5. Structural characterization and condition for measurement statistics preservation of a unital quantum operation

    Science.gov (United States)

    Lee, Kai-Yan; Fung, Chi-Hang Fred; Chau, H. F.

    2013-05-01

    We investigate the necessary and sufficient condition for a convex cone of positive semidefinite operators to be fixed by a unital quantum operation ϕ acting on finite-dimensional quantum states. By reducing this problem to the problem of simultaneous diagonalization of the Kraus operators associated with ϕ, we can completely characterize the kinds of quantum states that are fixed by ϕ. Our work has several applications. It gives a simple proof of the structural characterization of a unital quantum operation that acts on finite-dimensional quantum states—a result not explicitly mentioned in earlier studies. It also provides a necessary and sufficient condition for determining what kind of measurement statistics is preserved by a unital quantum operation. Finally, our result clarifies and extends the work of Størmer by giving a proof of a reduction theorem on the unassisted and entanglement-assisted classical capacities, coherent information, and minimal output Renyi entropy of a unital channel acting on a finite-dimensional quantum state.

  6. NUMATH: a nuclear-material-holdup estimator for unit operations and chemical processes

    Energy Technology Data Exchange (ETDEWEB)

    Krichinsky, A.M.

    1983-02-01

    A computer program, NUMATH (Nuclear Material Holdup Estimator), has been developed to estimate compositions of materials in vessels involved in unit operations and chemical processes. This program has been implemented in a remotely operated nuclear fuel processing plant. NUMATH provides estimates of the steady-state composition of materials residing in process vessels until representative samples can be obtained and chemical analyses can be performed. Since these compositions are used for inventory estimations, the results are determined for the cataloged in container-oriented files. The estimated compositions represent materials collected in applicable vessels - including consideration for materials previously acknowledged in these vessels. The program utilizes process measurements and simple performance models to estimate material holdup and distribution within unit operations. In simulated run-testing, NUMATH typically produced estimates within 5% of the measured inventories for uranium and within 8% of the measured inventories for thorium during steady-state process operation.

  7. Liquid phase methanol LaPorte process development unit: Modification, operation, and support studies

    Energy Technology Data Exchange (ETDEWEB)

    1991-02-02

    The primary focus of this Process Development Unit operating program was to prepare for a confident move to the next scale of operation with a simplified and optimized process. The main purpose of these runs was the evaluation of the alternate commercial catalyst (F21/0E75-43) that had been identified in the laboratory under a different subtask of the program. If the catalyst proved superior to the previous catalyst, then the evaluation run would be continued into a 120-day life run. Also, minor changes were made to the Process Development Unit system to improve operations and reliability. The damaged reactor demister from a previous run was replaced, and a new demister was installed in the intermediate V/L separator. The internal heat exchanger was equipped with an expansion loop to relieve thermal stresses so operation at higher catalyst loadings and gas velocities would be possible. These aggressive conditions are important for improving process economics. (VC)

  8. Toeplitz Operators on the Weighted Bergman Space over the Two-Dimensional Unit Ball

    Directory of Open Access Journals (Sweden)

    Alma García

    2015-01-01

    Full Text Available We extend the known results on commutative Banach algebras generated by Toeplitz operators with radial quasi-homogeneous symbols on the two-dimensional unit ball. Spherical coordinates previously used hid a possibility to detect an essentially wider class of symbols that can generate commutative Banach Toeplitz operator algebras. We characterize these new algebras describing their properties and, under a certain extra condition, construct the corresponding Gelfand theory.

  9. Analysis of United States Marine Corps Operations in Support of Humanitarian Assistance and Disaster Relief

    Science.gov (United States)

    2013-12-01

    unit (MEU), Bangladesh Cyclone Sidr, Operation Sea Angel II, Haiti earthquake 2010, Operation Unified Response, Great East Japan earthquake and...with respect to the conduct of HA/DR missions. We have collected data for the 2007 cyclone on the southwest coast of Bangladesh, the 2010 Haiti ...responded to the 2007 cyclone in Bangladesh, the 2010 Haiti earthquake, and the 2011 Japanese earthquake and subsequent tsunami, respectively. These

  10. Mortality on grower/finisher-only swine operations in the United States

    Directory of Open Access Journals (Sweden)

    Losinger W.C.

    1999-01-01

    Full Text Available For 53 grower/finisher-only swine operations that participated in the United States National Animal Health Monitoring System 1995 National Swine Study, mortality among finisher pigs ranged from 0 to 12.0% over a 6-month period. Twenty-six (49.1% had 2% mortality. Nine (17.0% operations experienced >4% mortality. Fisher's exact test revealed that operations with all-in all-out management were significantly more likely to have 1 grower/finisher pig came from another source. Larger operations (where >900 pigs entered the grower/finisher phase practiced all-in, all-out management more frequently than smaller operations, and had a lower mean percent mortality than smaller operations. Diagnosis of Salmonella in finisher pigs performed at a laboratory or by a veterinarian in the 12 months prior to interview was associated with both increased percent mortality and increased percent mortality per day.

  11. Design of optimal operating conditions of simulated moving bed adsorptive separation units

    Energy Technology Data Exchange (ETDEWEB)

    Storti, G. (Univ. degli Studi di Padova (Italy)); Baciocchi, R.; Mazzotti, M.; Morbidelli, M. (Politecnico di Milano (Italy). Dipt. di Chimica Fisica Applicata)

    1995-01-01

    The design of the optimal operating conditions for simulated moving bed (SMB) adsorptive separation units is considered. A procedure for the a priori selection of the operating conditions to achieve an assigned separation requirement is developed in the frame of equilibrium theory for the equivalent four section countercurrent unit, using a model where the adsorption equilibria are described through the constant selectivity stoichiometric model, while both mass transfer resistance and axial dispersion are neglected. The space of the operating parameters, i.e. the mass flow rate ratios m[sub j], is divided in regions with different separation regimes. Curves at constant outlets purity and recovery are drawn in the (m[sub 2],m[sub 3]) plane. The introduction of three performance parameters, desorbent requirement, adsorbent requirement, and productivity, allows the development of a procedure for the design of optimal operating conditions. This procedure is completed, accounting for the effect of the switching time on the separation performances, with a detailed model of the SMB unit, considering both axial dispersion and mass transfer resistance. This result constitutes a useful tool for determining the range of operating conditions to achieve an assigned separation requirement and then for selecting the optimal operating condition within this range.

  12. 40 CFR 62.15145 - What are the operating practice requirements for my municipal waste combustion unit?

    Science.gov (United States)

    2010-07-01

    ... requirements for my municipal waste combustion unit? 62.15145 Section 62.15145 Protection of Environment... Combustion Units Constructed on or Before August 30, 1999 Good Combustion Practices: Operating Requirements § 62.15145 What are the operating practice requirements for my municipal waste combustion unit? (a) You...

  13. Locating Depots for Capacitated Vehicle Routing

    CERN Document Server

    Goertz, Inge Li

    2011-01-01

    We study a location-routing problem in the context of capacitated vehicle routing. The input is a set of demand locations in a metric space and a fleet of k vehicles each of capacity Q. The objective is to locate k depots, one for each vehicle, and compute routes for the vehicles so that all demands are satisfied and the total cost is minimized. Our main result is a constant-factor approximation algorithm for this problem. To achieve this result, we reduce to the k-median-forest problem, which generalizes both k-median and minimum spanning tree, and which might be of independent interest. We give a (3+c)-approximation algorithm for k-median-forest, which leads to a (12+c)-approximation algorithm for the above location-routing problem, for any constant c>0. The algorithm for k-median-forest is just t-swap local search, and we prove that it has locality gap 3+2/t; this generalizes the corresponding result known for k-median. Finally we consider the "non-uniform" k-median-forest problem which has different cost ...

  14. Locating Depots for Capacitated Vehicle Routing

    DEFF Research Database (Denmark)

    Gørtz, Inge Li; Nagarajan, Viswanath

    2011-01-01

    We study a location-routing problem in the context of capacitated vehicle routing. The input to k-LocVRP is a set of demand locations in a metric space and a fleet of k vehicles each of capacity Q. The objective is to locate k depots, one for each vehicle, and compute routes for the vehicles so...... that all demands are satisfied and the total cost is minimized. Our main result is a constant-factor approximation algorithm for k-LocVRP. To achieve this result, we reduce k-LocVRP to the following generalization of k median, which might be of independent interest. Given a metric (V, d), bound k...... median forest, which leads to a (12+E)-approximation algorithm for k-LocVRP, for any constant E > 0. The algorithm for k median forest is t-swap local search, and we prove that it has locality gap 3 + 2 t ; this generalizes the corresponding result for k median [3]. Finally we consider the k median...

  15. Orchard Business Management. Unit II. Management and Analysis of the Orchard Operation.

    Science.gov (United States)

    Mullinix, Shauna K.

    This guide is intended for use in providing in-depth formal classroom and on-site instruction in the principles of business and financial management as they apply to operating and managing orchards. Designed to be used with an accompanying Orchard Business Management Record Book, this unit is devoted to management and analysis of an orchard…

  16. Hydrologic resources management program and underground test area operable unit fy 1997

    Energy Technology Data Exchange (ETDEWEB)

    Smith, D. F., LLNL

    1998-05-01

    This report present the results of FY 1997 technical studies conducted by the Lawrence Livermore National Laboratory (LLNL) as part of the Hydrology and Radionuclide Migration Program (HRMP) and Underground Test Area Operable Unit (UGTA). The HRMP is sponsored by the US Department of Energy to assess the environmental (radiochemical and hydrologic) consequences of underground nuclear weapons testing at the Nevada Test Site.

  17. China's first large-scale MA production unit operational in Shanxi

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    @@ Abrainchild of researchers of the CAS Institute of Coal Chemistry, a production unit capable of turning out 20,000 tons of maleic anhydride (MA) per year, the largest of its kind in China, has come into operation recently at the Shanxi Regent Taiming Chemical Co Ltd in Taiyuan, capital of north China's Shanxi Province.

  18. Predicting performance and situation awareness of robot operators in complex situations by unit task tests

    NARCIS (Netherlands)

    Mioch, T.; Smets, N.J.J.M.; Neerincx, M.A.

    2012-01-01

    Human-in-the-loop field tests of human-robot operations in high-demand situations provide serious constraints with respect to costs and control. A set of relatively simple unit tasks might be used to do part of the testing and to establish a benchmark for human-robot performance and situation awaren

  19. Liquid phase methanol LaPorte process development unit: Modification, operation, and support studies

    Energy Technology Data Exchange (ETDEWEB)

    1991-02-02

    This report consists of Detailed Data Acquisition Sheets for Runs E-6 and E-7 for Task 2.2 of the Modification, Operation, and Support Studies of the Liquid Phase Methanol Laporte Process Development Unit. (Task 2.2: Alternate Catalyst Run E-6 and Catalyst Activity Maintenance Run E-7).

  20. Ambiguity in Units and the Referents: Two Cases in Rational Number Operations

    Science.gov (United States)

    Rathouz, Margaret

    2010-01-01

    I explore the impact of ambiguous referral to the unit on understanding of decimal and fraction operations during episodes in two different mathematics courses for pre-service teachers (PSTs). In one classroom, the instructor introduces a rectangular area diagram to help the PSTs visualize decimal multiplication. A transcript from this classroom…

  1. Orchard Business Management. Unit II. Management and Analysis of the Orchard Operation.

    Science.gov (United States)

    Mullinix, Shauna K.

    This guide is intended for use in providing in-depth formal classroom and on-site instruction in the principles of business and financial management as they apply to operating and managing orchards. Designed to be used with an accompanying Orchard Business Management Record Book, this unit is devoted to management and analysis of an orchard…

  2. Predicting performance and situation awareness of robot operators in complex situations by unit task tests

    NARCIS (Netherlands)

    Mioch, T.; Smets, N.J.J.M.; Neerincx, M.A.

    2012-01-01

    Human-in-the-loop field tests of human-robot operations in high-demand situations provide serious constraints with respect to costs and control. A set of relatively simple unit tasks might be used to do part of the testing and to establish a benchmark for human-robot performance and situation awaren

  3. Use of the LITEE Lorn Manufacturing Case Study in a Senior Chemical Engineering Unit Operations Laboratory

    Science.gov (United States)

    Abraham, Nithin Susan; Abulencia, James Patrick

    2011-01-01

    This study focuses on the effectiveness of incorporating the Laboratory for Innovative Technology and Engineering Education (LITEE) Lorn Manufacturing case into a senior level chemical engineering unit operations course at Manhattan College. The purpose of using the case study is to demonstrate the relevance of ethics to chemical engineering…

  4. Lanreotide Depot: An Antineoplastic Treatment of Carcinoid or Neuroendocrine Tumors.

    Science.gov (United States)

    Wolin, Edward M; Manon, Amandine; Chassaing, Christophe; Lewis, Andy; Bertocchi, Laurent; Richard, Joel; Phan, Alexandria T

    2016-12-01

    Peptide drugs for antineoplastic therapies usually have low oral bioavailability and short in vivo half-lives, requiring less preferred delivery methods. Lanreotide depot is a sustained-release somatostatin analog (SSA) formulation produced via an innovative peptide self-assembly method. Lanreotide is approved in the USA and Europe to improve progression-free survival (PFS) in patients with unresectable gastroenteropancreatic neuroendocrine tumors (GEP-NETs) and also approved in Europe for symptom control in carcinoid syndrome associated with GEP-NETs. This review discusses how the distinct molecule and formulation of lanreotide depot provide advantages to patients and health care providers, as well as the most recent clinical evidence demonstrating the safety and efficacy of lanreotide depot in inhibiting tumor growth and controlling hormonal symptoms in GEP-NETs. The lanreotide depot formulation confers a remarkable pharmacokinetic profile with no excipients, comprised only of lanreotide acetate and water. Of note, lanreotide depot constitutes an example for peptide self-assembly based formulations, providing insights that could help future development of sustained-release formulations of other antineoplastic peptides. Most patients with GEP-NETs will present with inoperable or incurable disease; thus, medical management for symptoms and tumor control plays a crucial role. Recent long-term clinical studies have demonstrated that lanreotide depot is well tolerated, prolongs PFS in GEP-NET patients, and significantly reduces symptoms related to carcinoid syndrome. The unique depot formulation and delivery method of lanreotide confer advantages in the treatment of metastatic GEP-NETs, contributing to improvements in NET-related symptoms and PFS without reducing quality of life in this patient population.

  5. Qualitative risk assessment for the 100-HR-3 groundwater operable unit

    Energy Technology Data Exchange (ETDEWEB)

    Vukelich, S.E. [Golder Associates, Inc., Richland, WA (United States)

    1994-09-22

    This report provides the qualitative risk assessment for the 100-HR-3 operable unit on the Hanford Reservation. 100-HR-3 is a ground water unit. The purpose of the QRA at the 100-HR-3 operable unit is to focus on a predefined set of human and environmental exposure scenarios in order to provides sufficient information that will assist the Tri-Party signatories (Washington State Department of Ecology, EPA and US DOE) in making defensible decisions on the necessity of Interim Remedial Measures. Frequent- and occasional-use exposure scenarios are evaluated in the human health risk assessment to provide bounding estimates of risk. The ecological risk assessment consists of an evaluation of the risks to riparian and aquatic receptors which live in or near the Columbia River.

  6. Annual Summary Report Calendar Year 2000 for the 100-HR-3, 100-KR-4, and 100-NR-2 Operable Units and Pump-and-Treat Operations

    Energy Technology Data Exchange (ETDEWEB)

    G. B. Mitchem

    2001-08-22

    This annual progress and performance evaluation report discusses the groundwater remedial actions in the 100 Area, including the interim actions at the 100-HR-3 and 100-KR-4 Operable Units, and also discusses the expedited response action in the 100-NR-2 operable unit.

  7. Limited field investigation report for the 100-HR-3 operable unit

    Energy Technology Data Exchange (ETDEWEB)

    1994-09-01

    This limited field investigation (LFI) was conducted to assess the applicability of interim remedial measures (IRM) for reducing human health and environmental risks within the 100-HR-3 Groundwater Operable Unit. The 100-HR-3 Operable Unit is comprised of three subareas; the 100 D Area, the 100 H Area and those portions of the 600 Area between the two reactor areas. The operable unit is one of seven operable units associated with the 100 D and H Areas. Operable units 100-DR-1, 100-DR-2, 100-DR-3, 100-HR-1, 100-HR-2 and 100-IU-4 address contaminant sources while 100-HR-3 addresses contamination present in the underlying groundwater. The primary method of field investigation used during this LFI was the installation and sampling of monitoring wells. Samples were collected from the groundwater and soils, and submitted for laboratory analysis. Boreholes were surveyed for radiological contamination using downhole geophysical techniques to further delineate the locations and levels of contaminants. All samples were screened to ascertain the presence of volatile organic compounds and radionuclides. Analytical data were subjected to validation; all round one, two and three and a minimum of 10% of round four data associated with the LFI were validated. A screening method was used to identify contaminants of potential concern (COPC). This screening method eliminated from further consideration, constituents that were below background. Constituents which are considered non-toxic to humans were eliminated from the human health evaluation. Data consistency and blank contamination were also evaluated in the screening process. These COPC were then evaluated further in the qualitative risk assessment (QRA). A human health QRA was performed using conservative (maximum equilibrated contaminant levels from the LFI) analyses.

  8. Soil washing physical separations test procedure - 300-FF-1 operable unit

    Energy Technology Data Exchange (ETDEWEB)

    Belden, R.D.

    1993-10-08

    This procedure provides the operations approach, a field sampling plan, and laboratory procedures for a soil washing test to be conducted by Alternative Remedial Technologies, Inc. (ART) in the 300-FF-1 area at the Hanford site. The {open_quotes}Quality Assurance Project Plan for the Soil Washing Physical Separations Test, 300-FF-1 Operable Unit,{close_quotes} Hanford, Washington, Alternative Remedial Technologies, Inc., February 1994 (QAPP) is provided in a separate document that presents the procedural and organizational guidelines for this test. This document describes specifications, responsibilities, and general procedures to be followed to conduct physical separation soil treatability tests in the North Process Pond of the 300-FF-1 Operable Unit (OU) at the Hanford Site. These procedures are based on the {open_quotes}300-FF-1 Physical Separations CERCLA Treatability Test Plan, DOE/RL 92-2l,{close_quotes} (DOE-RL 1993).

  9. Remedial investigation/feasibility study work plan for the 100-KR-4 operable unit, Hanford Site, Richland, Washington

    Energy Technology Data Exchange (ETDEWEB)

    1992-09-01

    Four areas of the Hanford Site (the 100, 200, 300, and 1100 Areas) have been included on the US Environmental Protection Agency`s (EPA`s) National Priorities List (NPL) under the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). This work plan and the attached supporting project plans establish the operable unit setting and the objectives, procedures, tasks, and schedule for conducting the CERCLA remedial investigation/feasibility study (RI/FS) for the 100-KR-4 operable unit. The 100-K Area consists of the 100-KR-4 groundwater operable unit and three source operable units. The 100-KR-4 operable unit includes all contamination found in the aquifer soils and water beneath the 100-K Area. Source operable units include facilities and unplanned release sites that are potential sources of contamination.

  10. Performance study of a heat recovery tower with synthetic (polyurethane) flow channels to operate in a solar desalination unit

    OpenAIRE

    Frederico Pinheiro Rodrigues

    2010-01-01

    Because of the lack of drinkable water in various semi-arid regions and the necessary use of renewable energies, the present work presents a performance study of a heat recovery tower to operate in a solar desalination unit for decentralized water production. The solar desalination unit has two parts: a heating unit and a desalination unit.This work presents the field results with a desalination tower with synthetic (polyurethane) flow channels. The tower operation consists of the heating ...

  11. Architecture Study for a Fuel Depot Supplied from Lunar Assets

    Science.gov (United States)

    Perrin, Thomas M.; Casler, James G.

    2016-01-01

    This architecture study sought to determine the optimum architecture for a fuel depot supplied from lunar assets. Four factors - the location of propellant processing (on the Moon or on the depot), the depot location (on the Moon, L1, GEO, or LEO), the propellant transfer location (L1, GEO, or LEO), and the propellant transfer method (bulk fuel or canister exchange) were combined to identify 18 candidate architectures. Two design reference missions (DRMs) - a commercial satellite servicing mission and a Government cargo mission to Mars - created demand for propellants, while a propellant delivery DRM examined supply issues. The study concluded Earth-Moon L1 is the best location for an orbiting depot. For all architectures, propellant boiloff was less than anticipated, and was far overshadowed by delta-v requirements and resulting fuel consumption. Bulk transfer is the most flexible for both the supplier and customer. However, since canister exchange bypasses the transfer of bulk cryogens and necessary chilldown losses, canister exchange shows promise and merits further investigation. Overall, this work indicates propellant consumption and loss is an essential factor in assessing fuel depot architectures.

  12. EPA and Home Depot Offer Tips to Conserve Water, Save Money

    Science.gov (United States)

    (PHILADELPHIA - March 16, 2015) Officials from the U.S. Environmental Protection Agency and The Home Depot kicked off Fix a Leak Week today at The Home Depot store in South Philadelphia by demonstrating several simple, inexpensive improvement

  13. An Automatic Uav Mapping System for Supporting un (united Nations) Field Operations

    Science.gov (United States)

    Choi, K.; Cheon, J. W.; Kim, H. Y.; Lee, I.

    2016-06-01

    The United Nations (UN) has performed field operations worldwide such as peacekeeping or rescue missions. When such an operation is needed, the UN dispatches an operation team usually with a GIS (Geographic Information System) customized to a specific operation. The base maps for the GIS are generated mostly with satellite images which may not retain a high resolution and the current situation. To build an up-to-date high resolution map, we propose a UAV (unmanned aerial vehicle) based automatic mapping system, which can operate in a fully automatic way from the data acquisition of sensory data to the data processing for the generation of the geospatial products such as a mosaicked orthoimage of a target area. In this study, we analyse the requirements for UN field operations, suggest a UAV mapping system with an operation scenario, and investigate the applicability of the system. With the proposed system, we can construct a tailored GIS with up-to-date and high resolution base maps for a specific operation efficiently.

  14. An analysis of post-traumatic stress symptoms in United States Air Force drone operators.

    Science.gov (United States)

    Chappelle, Wayne; Goodman, Tanya; Reardon, Laura; Thompson, William

    2014-06-01

    Remotely piloted aircraft (RPA), commonly referred to as "drones," have emerged over the past decade as an innovative warfighting tool. Given there is a paucity of empirical research assessing drone operators, the purpose of this study was to assess for the prevalence of PTSD symptoms among this cohort. Of the 1084 United States Air Force (USAF) drone operators that participated, a total of 4.3% endorsed a pattern of symptoms of moderate to extreme level of severity meeting criteria outlined in the Diagnostic and Statistical Manual of Mental Disorders-4th edition. The incidence of PTSD among USAF drone operators in this study was lower than rates of PTSD (10-18%) among military personnel returning from deployment but higher than incidence rates (less than 1%) of USAF drone operators reported in electronic medical records. Although low PTSD rates may be promising, limitations to this study are discussed.

  15. Automated processing of whole blood units: operational value and in vitro quality of final blood components

    Science.gov (United States)

    Jurado, Marisa; Algora, Manuel; Garcia-Sanchez, Félix; Vico, Santiago; Rodriguez, Eva; Perez, Sonia; Barbolla, Luz

    2012-01-01

    Background The Community Transfusion Centre in Madrid currently processes whole blood using a conventional procedure (Compomat, Fresenius) followed by automated processing of buffy coats with the OrbiSac system (CaridianBCT). The Atreus 3C system (CaridianBCT) automates the production of red blood cells, plasma and an interim platelet unit from a whole blood unit. Interim platelet unit are pooled to produce a transfusable platelet unit. In this study the Atreus 3C system was evaluated and compared to the routine method with regards to product quality and operational value. Materials and methods Over a 5-week period 810 whole blood units were processed using the Atreus 3C system. The attributes of the automated process were compared to those of the routine method by assessing productivity, space, equipment and staffing requirements. The data obtained were evaluated in order to estimate the impact of implementing the Atreus 3C system in the routine setting of the blood centre. Yield and in vitro quality of the final blood components processed with the two systems were evaluated and compared. Results The Atreus 3C system enabled higher throughput while requiring less space and employee time by decreasing the amount of equipment and processing time per unit of whole blood processed. Whole blood units processed on the Atreus 3C system gave a higher platelet yield, a similar amount of red blood cells and a smaller volume of plasma. Discussion These results support the conclusion that the Atreus 3C system produces blood components meeting quality requirements while providing a high operational efficiency. Implementation of the Atreus 3C system could result in a large organisational improvement. PMID:22044958

  16. DEPOT: A Database of Environmental Parameters, Organizations and Tools

    Energy Technology Data Exchange (ETDEWEB)

    CARSON,SUSAN D.; HUNTER,REGINA LEE; MALCZYNSKI,LEONARD A.; POHL,PHILLIP I.; QUINTANA,ENRICO; SOUZA,CAROLINE A.; HIGLEY,KATHRYN; MURPHIE,WILLIAM

    2000-12-19

    The Database of Environmental Parameters, Organizations, and Tools (DEPOT) has been developed by the Department of Energy (DOE) as a central warehouse for access to data essential for environmental risk assessment analyses. Initial efforts have concentrated on groundwater and vadose zone transport data and bioaccumulation factors. DEPOT seeks to provide a source of referenced data that, wherever possible, includes the level of uncertainty associated with these parameters. Based on the amount of data available for a particular parameter, uncertainty is expressed as a standard deviation or a distribution function. DEPOT also provides DOE site-specific performance assessment data, pathway-specific transport data, and links to environmental regulations, disposal site waste acceptance criteria, other environmental parameter databases, and environmental risk assessment models.

  17. Postinjection Delirium/Sedation Syndrome with Olanzapine Depot Injection

    Science.gov (United States)

    Sarangula, Sadhvi Mythili; Mythri, Starlin Vijay; Sanjay, Y.; Reddy, M. S.

    2016-01-01

    After 1 year of introduction of olanzapine long-acting injectable (LAI) in India, many psychiatrists believe that it is a very affordable, well-tolerated, and effective second generation long-acting antipsychotic depot compared to not well tolerated but cheap first generation antipsychotic depots and to other second generation depots which are costly. However, reports of its possible adverse events in clinical settings are not yet published. We report what probably might be the first case of postinjection delirium/sedation syndrome (PDSS) in India. Although the occurrence is uncommon, incorrect understanding of this event may hinder the future use of the potentially useful olanzapine LAI. We review the available literature on the proposed diagnostic guidelines, mechanism of this event, precautions, and management of PDSS. PMID:27570354

  18. Causal ACTH-Depot Therapy during Pregnancies following Infertility Treatment

    Directory of Open Access Journals (Sweden)

    Rudolf Klimek

    2012-01-01

    Full Text Available The aim of this paper was to confirm the efficacy of adrenocorticotropin depot (ACTH-depot therapy in pregnancies with threatened miscarriage and preterm delivery through the desired stimulation of the adrenal glands controlled by the rest of organism. The activity of hypothalamic-pituitary-adrenal axis plays a key role in pregnancy. Such naturally stimulated endogenous corticosteroid hormones are free from unwanted side effects of their synthetics analogs. Low level of maternal blood ACTH and insufficient increase of induced by hypothalamic hormones oxytocinases (cystine-β-aminopeptidases were indication to ACTH-depot therapy (0.5 mg/week in our consecutive prospective studies. Contrary to antenatal use of synthetic corticosteroids, there are no temporal limits of this therapy, which has to be more often recommended into clinical prevention of fetal morbidity, treatment of premature delivery, and finally elimination of the newborn's mortality caused by the neuroendocrinological gestoses.

  19. A tabu-search heuristic for solving the multi-depot vehicle scheduling problem

    Directory of Open Access Journals (Sweden)

    Gilmar D'Agostini Oliveira Casalinho

    2014-08-01

    Full Text Available Currently the logistical problems are relying quite significantly on Operational Research in order to achieve greater efficiency in their operations. Among the problems related to the vehicles scheduling in a logistics system, the Multiple Depot Vehicle Scheduling Problem (MDVSP has been addressed in several studies. The MDVSP presupposes the existence of depots that affect the planning of sequences to which travel must be performed. Often, exact methods cannot solve large instances encountered in practice and in order to take them into account, several heuristic approaches are being developed. The aim of this study was thus to solve the MDVSP using a meta-heuristic based on tabu-search method. The main motivation for this work came from the indication that only recently the use of meta-heuristics is being applied to MDVSP context (Pepin et al. 2008 and, also, the limitations listed by Rohde (2008 in his study, which used the branch-and-bound in one of the steps of the heuristic presented to solve the problem, which has increased the time resolution. The research method for solving this problem was based on adaptations of traditional techniques of Operational Research, and provided resolutions presenting very competitive results for the MDVSP such as the cost of the objective function, number of vehicles used and computational time.

  20. Groundwater Monitoring Plan for the Reactor Technology Complex Operable Unit 2-13

    Energy Technology Data Exchange (ETDEWEB)

    Richard P. Wells

    2007-03-23

    This Groundwater Monitoring Plan describes the objectives, activities, and assessments that will be performed to support the on-going groundwater monitoring requirements at the Reactor Technology Complex, formerly the Test Reactor Area (TRA). The requirements for groundwater monitoring were stipulated in the Final Record of Decision for Test Reactor Area, Operable Unit 2-13, signed in December 1997. The monitoring requirements were modified by the First Five-Year Review Report for the Test Reactor Area, Operable Unit 2-13, at the Idaho National Engineering and Environmental Laboratory to focus on those contaminants of concern that warrant continued surveillance, including chromium, tritium, strontium-90, and cobalt-60. Based upon recommendations provided in the Annual Groundwater Monitoring Status Report for 2006, the groundwater monitoring frequency was reduced to annually from twice a year.

  1. Guidelines for establishing a donor human milk depot.

    Science.gov (United States)

    Geraghty, Sheela R; List, Betsy A; Morrow, Georgia B

    2010-02-01

    Human milk is the preferred choice for infant feeding. When a sick or premature infant's own mother's milk is unavailable, donor human milk is becoming more widely used. Many potential milk donors do not live within close proximity to the 10 North American not-for-profit milk banks. Transporting milk via commercial carriers can be inconvenient and costly for recipient banks. A network of donor human milk depots is one practical way to increase the quantity of available donor human milk. This article provides guidelines and practical suggestions for establishing a donor human milk depot.

  2. The reliability analysis of a separated, dual fail operational redundant strapdown IMU. [inertial measurement unit

    Science.gov (United States)

    Motyka, P.

    1983-01-01

    A methodology for quantitatively analyzing the reliability of redundant avionics systems, in general, and the dual, separated Redundant Strapdown Inertial Measurement Unit (RSDIMU), in particular, is presented. The RSDIMU is described and a candidate failure detection and isolation system presented. A Markov reliability model is employed. The operational states of the system are defined and the single-step state transition diagrams discussed. Graphical results, showing the impact of major system parameters on the reliability of the RSDIMU system, are presented and discussed.

  3. Aquatic studies at the 100-HR-3 and 100-NR-1 operable units

    Energy Technology Data Exchange (ETDEWEB)

    Cushing, C.E.

    1993-04-01

    Pacific Northwest Laboratory initiated a program to characterize selected aquatic biological populations to determine (1) existing levels of inorganic chemical and radionuclide contamination, and (2) the populations` suitability as indicators of chemical releases during cleanup activities at the US Department of Energy`s Hanford Site. Following work plans for the ground-water operable units, lower trophic levels in the aquatic habitat (periphyton and caddisfly larvae) were evaluated for contaminants at the 100-HR-3 Operable Unit and 100-NR-1 Operable Unit. The results were evaluated to determine the need for further sampling. If the results showed no significant contamination compared to upriver levels, sampling would be discontinued. The periphyton community appears to be suitable for determining contamination levels. Baseline concentrations for stable chromium were established and will be useful for comparing samples collected when contaminant release is expected. Concentrations of {sup 60}Co, {sup 90}Sr, and {sup 137}Cs in periphyton were essentially below detectable limits, which will also make this community useful in detecting potential releases of radionuclides during cleanup activities. Levels for both stable chromium and radionuclides were essentially below detection limits for caddisfly larvae. Thus, these organisms may be used to monitor suspected contaminant releases from cleanup activities; if concentrations exceed detection limits, they may be related to these activities. Two candidate threatened and endangered species of molluscs occur in the Hanford Reach of the Columbia River. These are the shortface lanx (Fisherola nuttalli), which is a Washington State candidate species, and the Columbia pebblesnail (Fluminicola columbiana), which is both a state and federal candidate species. Specimens of the shortface lanx were observed in the vicinity of N Springs (100-NR-1 Operable Unit); they likely occur throughout this area.

  4. Aquatic studies at the 100-HR-3 and 100-NR-1 operable units

    Energy Technology Data Exchange (ETDEWEB)

    Cushing, C.E.

    1993-04-01

    Pacific Northwest Laboratory initiated a program to characterize selected aquatic biological populations to determine (1) existing levels of inorganic chemical and radionuclide contamination, and (2) the populations' suitability as indicators of chemical releases during cleanup activities at the US Department of Energy's Hanford Site. Following work plans for the ground-water operable units, lower trophic levels in the aquatic habitat (periphyton and caddisfly larvae) were evaluated for contaminants at the 100-HR-3 Operable Unit and 100-NR-1 Operable Unit. The results were evaluated to determine the need for further sampling. If the results showed no significant contamination compared to upriver levels, sampling would be discontinued. The periphyton community appears to be suitable for determining contamination levels. Baseline concentrations for stable chromium were established and will be useful for comparing samples collected when contaminant release is expected. Concentrations of [sup 60]Co, [sup 90]Sr, and [sup 137]Cs in periphyton were essentially below detectable limits, which will also make this community useful in detecting potential releases of radionuclides during cleanup activities. Levels for both stable chromium and radionuclides were essentially below detection limits for caddisfly larvae. Thus, these organisms may be used to monitor suspected contaminant releases from cleanup activities; if concentrations exceed detection limits, they may be related to these activities. Two candidate threatened and endangered species of molluscs occur in the Hanford Reach of the Columbia River. These are the shortface lanx (Fisherola nuttalli), which is a Washington State candidate species, and the Columbia pebblesnail (Fluminicola columbiana), which is both a state and federal candidate species. Specimens of the shortface lanx were observed in the vicinity of N Springs (100-NR-1 Operable Unit); they likely occur throughout this area.

  5. EXTENDED CES(A)RO OPERATORS ON THE BLOCH SPACE IN THE UNIT BALL OF Cn

    Institute of Scientific and Technical Information of China (English)

    胡璋剑

    2003-01-01

    The paper defines an extended Cesàro operator Tg with holomorphic symbolg in the unit ball B of Cn asWhere g(z)= ∑j=1∑n zj g/ zj is the radial derivative of g. In this paper, the author characterizes g for which Tg is bounded (or compact) on the Bloch spaceB and the little Blochspace B0.

  6. Contaminant Attenuation and Transport Characterization of 200-DV-1 Operable Unit Sediment Samples

    Energy Technology Data Exchange (ETDEWEB)

    Truex, Michael J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Szecsody, James E. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Qafoku, Nikolla [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Strickland, Christopher E. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Moran, James J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Lee, Brady D. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Snyder, Michelle M.V. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Lawter, Amanda R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Resch, Charles T. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Gartman, Brandy N. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Zhong, Lirong [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Nims, Megan K. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Saunders, Danielle L. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Williams, Benjamin D. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Horner, Jacob A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Leavy, Ian I. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Baum, Steven R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Christiansen, Beren B. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Clayton, Ray E. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); McElroy, Erin M. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Appriou, Delphine [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Tyrrell, Kimberly J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Striluk, Miranda L. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2017-05-15

    A laboratory study was conducted to quantify contaminant attenuation processes and associated contaminant transport parameters that are needed to evaluate transport of contaminants through the vadose zone to the groundwater. The laboratory study information, in conjunction with transport analyses, can be used as input to evaluate the feasibility of Monitored Natural Attenuation and other remedies for the 200-DV-1 Operable Unit at the Hanford Site.

  7. Discrete Sampling Test Plan for the 200-BP-5 Operable Unit

    Energy Technology Data Exchange (ETDEWEB)

    Sweeney, Mark D.

    2010-02-04

    The Discrete Groundwater Sampling Project is conducted by the Pacific Northwest National Laboratory (PNNL) on behalf of CH2M HILL Plateau Remediation Company. The project is focused on delivering groundwater samples from proscribed horizons within select groundwater wells residing in the 200-BP-5 Operable Unit (200-BP-5 OU) on the Hanford Site. This document provides the scope, schedule, methodology, and other details of the PNNL discrete sampling effort.

  8. Data validation report for the 100-HR-3 Operable Unit, fifth round groundwater samples

    Energy Technology Data Exchange (ETDEWEB)

    Vukelich, S.E. [Kearney (A.T.), Inc., Chicago, IL (United States)

    1994-01-20

    The data from the chemical analysis of 68 samples from the 100-HR-3 Operable Unit Third Quarter 1993 Groundwater Sampling Investigation and their related quality assurance samples were reviewed and validated to verify that reported sample results were of sufficient quality to support decisions regarding remedial actions performed at the site. Sample analysis included inorganics and general chemical parameters. Fifty three samples were validated for radiochemical parameters.

  9. Baseline groundwater model update for p-area groundwater operable unit, NBN

    Energy Technology Data Exchange (ETDEWEB)

    Ross, J. [Savannah River Site (SRS), Aiken, SC (United States); Amidon, M. [Savannah River Site (SRS), Aiken, SC (United States)

    2015-09-01

    This report documents the development of a numerical groundwater flow and transport model of the hydrogeologic system of the P-Area Reactor Groundwater Operable Unit at the Savannah River Site (SRS) (Figure 1-1). The P-Area model provides a tool to aid in understanding the hydrologic and geochemical processes that control the development and migration of the current tritium, tetrachloroethene (PCE), and trichloroethene (TCE) plumes in this region.

  10. Initial closed operation of the CELSS Test Facility Engineering Development Unit

    Science.gov (United States)

    Kliss, M.; Blackwell, C.; Zografos, A.; Drews, M.; MacElroy, R.; McKenna, R.; Heyenga, A. G.

    2003-01-01

    As part of the NASA Advanced Life Support Flight Program, a Controlled Ecological Life Support System (CELSS) Test Facility Engineering Development Unit has been constructed and is undergoing initial operational testing at NASA Ames Research Center. The Engineering Development Unit (EDU) is a tightly closed, stringently controlled, ground-based testbed which provides a broad range of environmental conditions under which a variety of CELSS higher plant crops can be grown. Although the EDU was developed primarily to provide near-term engineering data and a realistic determination of the subsystem and system requirements necessary for the fabrication of a comparable flight unit, the EDU has also provided a means to evaluate plant crop productivity and physiology under controlled conditions. This paper describes the initial closed operational testing of the EDU, with emphasis on the hardware performance capabilities. Measured performance data during a 28-day closed operation period are compared with the specified functional requirements, and an example of inferring crop growth parameters from the test data is presented. Plans for future science and technology testing are also discussed. Published by Elsevier Science Ltd on behalf of COSPAR.

  11. Enhanced teaching and student learning through a simulator-based course in chemical unit operations design

    Science.gov (United States)

    Ghasem, Nayef

    2016-07-01

    This paper illustrates a teaching technique used in computer applications in chemical engineering employed for designing various unit operation processes, where the students learn about unit operations by designing them. The aim of the course is not to teach design, but rather to teach the fundamentals and the function of unit operation processes through simulators. A case study presenting the teaching method was evaluated using student surveys and faculty assessments, which were designed to measure the quality and effectiveness of the teaching method. The results of the questionnaire conclusively demonstrate that this method is an extremely efficient way of teaching a simulator-based course. In addition to that, this teaching method can easily be generalised and used in other courses. A student's final mark is determined by a combination of in-class assessments conducted based on cooperative and peer learning, progress tests and a final exam. Results revealed that peer learning can improve the overall quality of student learning and enhance student understanding.

  12. [Air conditioning units and warm air blankets in the operating room].

    Science.gov (United States)

    Kerwat, Klaus; Piechowiak, Karolin; Wulf, Hinnerk

    2013-01-01

    Nowadays almost all operating rooms are equipped with air conditioning (AC units). Their main purpose is climatization, like ventilation, moisturizing, cooling and also the warming of the room in large buildings. In operating rooms they have an additional function in the prevention of infections, especially the avoidance of postoperative wound infections. This is achieved by special filtration systems and by the creation of specific air currents. Since hypothermia is known to be an unambiguous factor for the development of postoperative wound infections, patients are often actively warmed intraoperatively using warm air blankets (forced-air warming units). In such cases it is frequently discussed whether such warm air blankets affect the performance of AC units by changing the air currents or whether, in contrast, have exactly the opposite effect. However, it has been demonstrated in numerous studies that warm air blankets do not have any relevant effect on the functioning of AC units. Also there are no indications that their use increases the rate of postoperative wound infections. By preventing the patient from experiencing hypothermia, the rate of postoperative wound infections can even be decreased thereby. © Georg Thieme Verlag Stuttgart · New York.

  13. Operation and results of the prototype KM3NeT detection unit

    Science.gov (United States)

    Biagi, Simone

    2016-07-01

    KM3NeT will be a km3-scale neutrino telescope in the Mediterranean Sea. The detector will consist of blocks of about one hundred detection units. Each detection unit will host 18 digital optical modules, connected along a 700 m-long vertical structure. Electro-optical cables allow for data transmission and power supply to the optical modules. The optical module comprises 31 photomultiplier tubes of 3'', instruments to monitor environmental variables and electronic boards to communicate onshore and operate the photomultipliers. A prototype detection unit has been deployed in May 2014 at the KM3NeT-It installation site 80 km SE offshore of Capo Passero, Sicily. This prototype allowed to test the deployment procedures, the mechanics and the electronic of the apparatus, the data taking and analysis procedures. A general description of the detector and some results of the prototype are presented. The first detection unit of the KM3NeT neutrino telescope will be deployed and become operative by the end of 2015.

  14. Operation and results of the prototype KM3NeT detection unit

    Directory of Open Access Journals (Sweden)

    Biagi Simone

    2016-01-01

    Full Text Available KM3NeT will be a km3-scale neutrino telescope in the Mediterranean Sea. The detector will consist of blocks of about one hundred detection units. Each detection unit will host 18 digital optical modules, connected along a 700 m-long vertical structure. Electro-optical cables allow for data transmission and power supply to the optical modules. The optical module comprises 31 photomultiplier tubes of 3′′, instruments to monitor environmental variables and electronic boards to communicate onshore and operate the photomultipliers. A prototype detection unit has been deployed in May 2014 at the KM3NeT-It installation site 80 km SE offshore of Capo Passero, Sicily. This prototype allowed to test the deployment procedures, the mechanics and the electronic of the apparatus, the data taking and analysis procedures. A general description of the detector and some results of the prototype are presented. The first detection unit of the KM3NeT neutrino telescope will be deployed and become operative by the end of 2015.

  15. 40 CFR 60.1200 - What are the operating practice requirements for my municipal waste combustion unit?

    Science.gov (United States)

    2010-07-01

    ... requirements for my municipal waste combustion unit? 60.1200 Section 60.1200 Protection of Environment... SOURCES Standards of Performance for Small Municipal Waste Combustion Units for Which Construction is... Good Combustion Practices: Operating Requirements § 60.1200 What are the operating practice...

  16. Operational Evaluation of VEGGIE Food Production System in the Habitat Demonstration Unit

    Science.gov (United States)

    Stutte, Gary W.; Newsham, Gerard; Morrow, Robert M.; Wheeler, Raymond M.

    2011-01-01

    The 2010 Desert Research and Technology Studies (DRATS) of the VEGGIE Food Production System in the Habitat Demonstration Unit (HDU) Pressurized Excursion Module (PEM) was the first operational evaluation of salad crop production technology in a NASA analog test. A systematic evaluation of rooting media and nutrient delivery systems were evaluated for three lettuce cultivars that have shown promise as candidates for a surface based food production system. The VEGGIE nutrient delivery system worked well, was able to be maintained by multiple operators with a minimum of training, and supported excellent lettuce growth for the duration of the test. A Hazard Analysis and Critical Control Point (HACCP) evaluation was performed using ProSan(tm) as sanitation agent prior to consumption was approved, and the crew was allowed to consume the lettuce grown using the VEGGIE light cap and gravity based nutrient delivery system at the completion of the 14-day DRAT field test. The DRAT field test validated the crew operations; Growth of all lettuce cultivars was excellent. The operational DRAT field testing in the HDU identified light quality issues related to morphology and pigment development that will need to be addressed through additional testing. Feedback from the crew, ground support personnel, and human factors leads was uniformly positive on the psychological value of having the crop production system in the excursion module. A number of areas have been identified for future work, to minimize the "footprint" of the Food Production system through creative use of unused wall and floor space in the unit.

  17. Operation Evaluation of the VEGGIE Food Production System in the Habitat Demonstration Unit

    Science.gov (United States)

    Stutte, Gary W.; Newsham, Gerard; Morrow, Robert M.; Wheeler, Raymond M.

    2011-01-01

    The 2010 Desert Research and Technology Studies (DRATS) of the VEGGIE Food Production System in the Habitat Demonstration Unit (HDU) Pressurized Excursion Module (PEM) was the first operational evaluation of salad crop production technology in a NASA analog test. A systematic evaluation of rooting media and nutrient delivery systems were evaluated for three lettuce cultivars that have shown promise as candidates for a surface based food production system. The VEGGIE nutrient delivery system worked well, was able to be maintained by multiple operators with a minimum of training, and supported excellent lettuce growth for the duration of the test. A Hazard Analysis and Critical Control Point (HACCP) evaluation was performed using ProSantm as sanitation agent prior to consumption was approved, and the crew was allowed to consume the lettuce grown using the VEGGIE light cap and gravity based nutrient delivery system at the completion of the 14-day DRAT field test. The DRAT field test validated the crew operations; Growth of all lettuce cultivars was excellent. The operational DRAT field testing in the HDU identified light quality issues related to morphology and pigment development that will need to be addressed through additional testing. Feedback from the crew, ground support personnel, and human factors leads was uniformly positive on the psychological value of having the crop production system in the excursion module. A number of areas have been identified for future work, to minimize the "footprint" of the Food Production system through creative use of unused wall and floor space in the unit.

  18. Pilot-scale treatability test plan for the 200-BP-5 operable unit

    Energy Technology Data Exchange (ETDEWEB)

    1994-08-01

    This document presents the treatability test plan for pilot-scale pump and treat testing at the 200-BP-5 Operable Unit. This treatability test plan has been prepared in response to an agreement between the U.S. Department of Energy (DOE), the U.S. Environmental Protection Agency (EPA), and the State of Washington Department of Ecology (Ecology), as documented in Hanford Federal Facility Agreement and Consent Order (Tri-Party Agreement, Ecology et al. 1989a) Change Control Form M-13-93-03 (Ecology et al. 1994) and a recent 200 NPL Agreement Change Control Form (Appendix A). The agreement also requires that, following completion of the activities described in this test plan, a 200-BP-5 Operable Unit Interim Remedial Measure (IRM) Proposed Plan be developed for use in preparing an Interim Action Record of Decision (ROD). The IRM Proposed Plan will be supported by the results of this treatability test plan, as well as by other 200-BP-5 Operable Unit activities (e.g., development of a qualitative risk assessment). Once issued, the Interim Action ROD will specify the interim action(s) for groundwater contamination at the 200-BP-5 Operable Unit. The treatability test approach is to conduct a pilot-scale pump and treat test for each of the two contaminant plumes associated with the 200-BP-5 Operable Unit. Primary contaminants of concern are {sup 99}Tc and {sup 60}Co for underwater affected by past discharges to the 216-BY Cribs, and {sup 90}Sr, {sup 239/240}Pu, and Cs for groundwater affected by past discharges to the 216-B-5 Reverse Well. The purpose of the pilot-scale treatability testing presented in this testplan is to provide the data basis for preparing an IRM Proposed Plan. To achieve this objective, treatability testing must: Assess the performance of groundwater pumping with respect to the ability to extract a significant amount of the primary contaminant mass present in the two contaminant plumes.

  19. International Space Station United States Orbital Segment Oxygen Generation System On-Orbit Operational Experience

    Science.gov (United States)

    Erickson, Robert J.; Howe, John, Jr.; Kulp, Galen W.; VanKeuren, Steven P.

    2008-01-01

    The International Space Station (ISS) United States Orbital Segment (USOS) Oxygen Generation System (OGS) was originally intended to be installed in ISS Node 3. The OGS rack delivery was accelerated, and it was launched to ISS in July of 2006 and installed in the US Laboratory Module. Various modification kits were installed to provide its interfaces, and the OGS was first activated in July of 2007 for 15 hours, In October of 2007 it was again activated for 76 hours with varied production rates and day/night cycling. Operational time in each instance was limited by the quantity of feedwater in a Payload Water Reservoir (PWR) bag. Feedwater will be provided by PWR bag until the USOS Water Recovery System (WRS) is delivered to SS in fall of 2008. This paper will discuss operating experience and characteristics of the OGS, as well as operational issues and their resolution.

  20. Locoregional cancer therapy using polymer-based drug depots

    NARCIS (Netherlands)

    Ramazani, Farshad; van Nostrum, Cornelis F.; Storm, G; Kiessling, Fabian; Lammers, Twan; Hennink, Wim E.; Kok, Robbert J.

    2016-01-01

    Locoregional delivery of anticancer drugs is an attractive approach to minimize adverse effects associated with intravenous chemotherapy. Polymer-based drug depots injected or implanted intratumorally or adjacent to the tumor can provide long-term local drug exposure. This review highlights studies

  1. Radiological Scoping Survey of the Scotia Depot Scotia, New York

    Energy Technology Data Exchange (ETDEWEB)

    E. N. Bailey

    2005-02-05

    At the request of the Defense Logistics Agency, the Oak Ridge Institute for Science and Education conducted radiological scoping surveys of the Scotia Depot during the period of September 24 through 27, 2007. The scoping survey included visual inspections and limited radiological surveys performed in accordance with area classification that included surface scans, total and removable activity measurements, and soil sampling.

  2. Total Quality Management Implementation Plan Defense Depot Memphis

    Science.gov (United States)

    1989-07-01

    Total Quality Management Implementation...improvement goals, implementation strategy and milestones. 6’ SEP 291989 /; ELECTE i= E 14. SUBJECT TERMS 15. NUMBER OF PAGES TQM ( Total Quality Management ), Depot...changing work environment where change is the norm. We are talking about changes in attitudes and habits. Total Quality Management is not a

  3. Locoregional cancer therapy using polymer-based drug depots

    NARCIS (Netherlands)

    Ramazani, Farshad; van Nostrum, Cornelis F.; Storm, G; Kiessling, Fabian; Lammers, Twan; Hennink, Wim E.; Kok, Robbert J.

    2016-01-01

    Locoregional delivery of anticancer drugs is an attractive approach to minimize adverse effects associated with intravenous chemotherapy. Polymer-based drug depots injected or implanted intratumorally or adjacent to the tumor can provide long-term local drug exposure. This review highlights studies

  4. Fatty acid composition of subcutaneous and kidney fat depots of ...

    African Journals Online (AJOL)

    which had been kept for 90 days on one of five different diets. The diets were ..... A comparison of the fatty acid content of fat depots in the Boer goat as reported ... owing to the influencethat nutrition, notably the carbohydrate source, has on the ...

  5. Redistributing Stock in Library Systems with a Depot

    NARCIS (Netherlands)

    van der Heide, Gerlach; Roodbergen, Kees Jan; van Foreest, Nicky

    Public library organizations often utilize depots for carrying out shipments to libraries in case of stock-outs and for storing low demand rental items at low cost. Similar systems may be employed by rental companies for other rental products such as tools, DVDs, and jewelry. Since shipments deplete

  6. Discrete phase model representation of particulate matter (PM) for simulating PM separation by hydrodynamic unit operations.

    Science.gov (United States)

    Dickenson, Joshua A; Sansalone, John J

    2009-11-01

    Modeling the separation of dilute particulate matter (PM) has been a topic of interest since the introduction of unit operations for clarification of rainfall-runoff. One consistent yet controversial issue is the representation of PM and PM separation mechanisms for treatment. While Newton's Law and surface overflow rate were utilized, many historical models represented PM as a lumped gravimetric index largely out of economy and lack of particle analysis methods. As a result such models did not provide information about particle fate in or through a unit operation. In this study, PM discrete phase modeling (DPM) and computational fluid dynamics (CFD) are applied to model PM fate as a function of particle size and flow rate in two common types of hydrodynamic separator (HS) units. The study examines the discretization requirements (as a discretization number, DN) and errors for particle size distributions (PSDs) that range from the common heterodisperse to a monodisperse PSD. PSDs are categorized based on granulometric indices. Results focus on ensuring modeling accuracy while examining the role of size dispersivity and overall PM fineness on DN requirements. The fate of common heterodisperse PSDs is accurately predicted for a DN of 16, whereas a single particle size index, commonly the d(50m), is limited to monodisperse PSDs in order to achieve similar accuracy.

  7. The Applied Meteorology Unit: Nineteen Years Successfully Transitioning Research into Operations for America's Space Program

    Science.gov (United States)

    Madura, John T.; Bauman, William H.; Merceret, Francis J.; Roeder, William P.; Brody, Frank C.; Hagemeyer, Bartlett C.

    2010-01-01

    The Applied Meteorology Unit (AMU) provides technology transition and technique development to improve operational weather support to the Space Shuttle and the entire American space program. The AMU is funded and managed by NASA and operated by a contractor that provides five meteorologists with a diverse mix of advanced degrees, operational experience, and associated skills including data processing, statistics, and the development of graphical user interfaces. The AMU's primary customers are the U.S. Air Force 45th Weather Squadron at Patrick Air Force Base, the National Weather Service Spaceflight Meteorology Group at NASA Johnson Space Center, and the National Weather Service Melbourne FL Forecast Office. The AMU has transitioned research into operations for nineteen years and worked on a wide range of topics, including new forecasting techniques for lightning probability, synoptic peak winds,.convective winds, and summer severe weather; satellite tools to predict anvil cloud trajectories and evaluate camera line of sight for Space Shuttle launch; optimized radar scan strategies; evaluated and implemented local numerical models; evaluated weather sensors; and many more. The AMU has completed 113 projects with 5 more scheduled to be completed by the end of 2010. During this rich history, the AMU and its customers have learned many lessons on how to effectively transition research into operations. Some of these lessons learned include collocating with the operational customer and periodically visiting geographically separated customers, operator submitted projects, consensus tasking process, use of operator primary advocates for each project, customer AMU liaisons with experience in both operations and research, flexibility in adapting the project plan based on lessons learned during the project, and incorporating training and other transition assistance into the project plans. Operator involvement has been critical to the AMU's remarkable success and many awards

  8. Effect of Depot Medroxyprogesterone Acetate on Glucose Tolerance in Generalized Lipodystrophy

    Science.gov (United States)

    Yauger, Belinda J.; Gorden, Phillip; Park, Jean; Cochran, Elaine; Stratton, Pamela

    2012-01-01

    BACKGROUND Lipodystrophy is a rare condition causing severe insulin resistance and frank diabetes. Depot medroxyprogesterone acetate (DMPA), a commonly used contraceptive, may worsen glucose tolerance in diabetics and those with lipodystrophy. CASE A young woman with generalized lipodystrophy, who previously required greater than 1,000 units of insulin daily, had a normal hemoglobin A1c on leptin and metformin only. After an injection of DMPA, she developed severe hyperglycemia. Her levels returned to near normal only with extremely high doses of insulin (up to 1,700 units/d) and increased doses of leptin and metformin. CONCLUSION Progestin-only contraceptives may detrimentally affect glucose tolerance, particularly in patients with lipodystrophy, a cause of severe insulin resistance and leptin deficiency. One DMPA injection appeared to profoundly alter glucose metabolism in this patient with frank diabetes resulting from lipodystrophy. The effect of progestin-only contraceptives on glucose tolerance should be monitored closely in any diabetic patient. PMID:18669758

  9. Multiobjective Optimization of a Counterrotating Type Pump-Turbine Unit Operated at Turbine Mode

    Directory of Open Access Journals (Sweden)

    Jin-Hyuk Kim

    2014-05-01

    Full Text Available A multiobjective optimization for improving the turbine output and efficiency of a counterrotating type pump-turbine unit operated at turbine mode was carried out in this work. The blade geometry of both the runners was optimized using a hybrid multiobjective evolutionary algorithm coupled with a surrogate model. Three-dimensional Reynolds-averaged Navier-Stokes equations with the shear stress transport turbulence model were discretized by finite volume approximations and solved on hexahedral grids to analyze the flow in the pump-turbine unit. As major hydrodynamic performance parameters, the turbine output and efficiency were selected as objective functions with two design variables related to the hub profiles of both the runner blades. These objectives were numerically assessed at twelve design points selected by Latin hypercube sampling in the design space. Response surface approximation models for the objectives were constructed based on the objective function values at the design points. A fast nondominated sorting genetic algorithm for the local search coupled with the response surface approximation models was applied to determine the global Pareto-optimal solutions. The trade-off between the two objectives was determined and described with respect to the Pareto-optimal solutions. The results of this work showed that the turbine outputs and efficiencies of optimized pump-turbine units were simultaneously improved in comparison to the reference unit.

  10. 78 FR 5167 - BE-9: Quarterly Survey of Foreign Airline Operators' Revenues and Expenses in the United States

    Science.gov (United States)

    2013-01-24

    ... Bureau of Economic Analysis XRIN 0691-XC003 BE-9: Quarterly Survey of Foreign Airline Operators' Revenues... Foreign Airline Operators' Revenues and Expenses in the United States (BE-9). This mandatory survey is..., agents, or other representatives of foreign airline operators that transport passengers or freight and...

  11. A two-stage approach to the depot shunting driver assignment problem with workload balance considerations

    Science.gov (United States)

    Gronalt, Manfred; Sun, Yan

    2017-01-01

    Due to its environmentally sustainable and energy-saving characteristics, railway transportation nowadays plays a fundamental role in delivering passengers and goods. Emerged in the area of transportation planning, the crew (workforce) sizing problem and the crew scheduling problem have been attached great importance by the railway industry and the scientific community. In this paper, we aim to solve the two problems by proposing a novel two-stage optimization approach in the context of the electric multiple units (EMU) depot shunting driver assignment problem. Given a predefined depot shunting schedule, the first stage of the approach focuses on determining an optimal size of shunting drivers. While the second stage is formulated as a bi-objective optimization model, in which we comprehensively consider the objectives of minimizing the total walking distance and maximizing the workload balance. Then we combine the normalized normal constraint method with a modified Pareto filter algorithm to obtain Pareto solutions for the bi-objective optimization problem. Furthermore, we conduct a series of numerical experiments to demonstrate the proposed approach. Based on the computational results, the regression analysis yield a driver size predictor and the sensitivity analysis give some interesting insights that are useful for decision makers. PMID:28704489

  12. Selection of Forklift Unit for Warehouse Operation by Applying Multi-Criteria Analysis

    Directory of Open Access Journals (Sweden)

    Predrag Atanasković

    2013-07-01

    Full Text Available This paper presents research related to the choice of the criteria that can be used to perform an optimal selection of the forklift unit for warehouse operation. The analysis has been done with the aim of exploring the requirements and defining relevant criteria that are important when investment decision is made for forklift procurement, and based on the conducted research by applying multi-criteria analysis, to determine the appropriate parameters and their relative weights that form the input data and database for selection of the optimal handling unit. This paper presents an example of choosing the optimal forklift based on the selected criteria for the purpose of making the relevant investment decision.

  13. Cooling unit for a superconducting power cable. Two years successful operation

    Energy Technology Data Exchange (ETDEWEB)

    Herzog, Friedhelm [Messer Group GmbH, Krefeld (Germany); Kutz, Thomas [Messer Industriegase GmbH, Bad Soden (Germany); Stemmle, Mark [Nexans Deutschland GmbH, Hannover (Germany); Kugel, Torsten [Westnetz GmbH, Essen (Germany)

    2016-07-01

    High temperature super conductors (HTS) can efficiently be cooled with liquid nitrogen down to a temperature of 64 K (-209 C). Lower temperatures are not practical, because nitrogen becomes solid at 63 K (-210 C). To achieve this temperature level the coolant has to be vaporized below atmospheric pressure. Messer has developed a cooling unit with an adequate vacuum subcooler, a liquid nitrogen circulation system, and a storage vessel for cooling an HTS power cable. The cooling unit was delivered in 2013 for the German AmpaCity project of RWE Deutschland AG, Nexans and Karlsruhe Institute of Technology. Within this project RWE and Nexans installed the worldwide longest superconducting power cable in the city of Essen, Germany. The cable is in operation since March 10th, 2014.

  14. Cooling unit for the AmpaCity project - One year successful operation

    Science.gov (United States)

    Herzog, Friedhelm; Kutz, Thomas; Stemmle, Mark; Kugel, Torsten

    2016-12-01

    High temperature super conductors (HTS) can efficiently be cooled with liquid nitrogen down to a temperature of 64 K (-209 °C). Lower temperatures are not practical, because at 63 K (-210 °C) nitrogen becomes solid. To achieve this temperature level the coolant has to be vaporized below atmospheric pressure. Messer has developed a cooling unit with an adequate vacuum subcooler, a liquid nitrogen circulation system, and a storage vessel for cooling an HTS-power cable. Liquid nitrogen is circulated through the superconducting cable to take out the heat, and afterward it is pumped through the subcooler to be recooled. In the circulation system liquid nitrogen is used as a dielectric fluid and as a heat transfer medium. It stays always liquid (subcooled) and does not vaporize. On the secondary side of the subcooler liquid nitrogen from the storage vessel is used as refrigerant. It is vaporized under a pressure of 150 mbar to achieve the desired low temperatures. The cooling unit was delivered in 2013 for the German AmpaCity project of RWE Deutschland AG, Nexans and Karlsruhe Institute of Technology. Within this project RWE and Nexans installed the worldwide longest superconducting power cable in the city of Essen, Germany. The cooling unit cools a 10 kV concentric HTS cable (40 MV A) with a length of 1000 m. The cable is in operation since March 10th, 2014. After more than one year of practical operation many important figures from cable and cooling unit are available. These figures are discussed and a total energy balance is shown to compare liquid nitrogen cooling with alternative mechanical cooling systems.

  15. Operable Unit 3: Proposed Plan/Environmental Assessment for interim remedial action

    Energy Technology Data Exchange (ETDEWEB)

    1993-12-01

    This document presents a Proposed Plan and an Environmental Assessment for an interim remedial action to be undertaken by the US Department of Energy (DOE) within Operable Unit 3 (OU3) at the Fernald Environmental Management Project (FEMP). This proposed plan provides site background information, describes the remedial alternatives being considered, presents a comparative evaluation of the alternatives and a rationnale for the identification of DOE`s preferred alternative, evaluates the potential environmental and public health effects associated with the alternatives, and outlines the public`s role in helping DOE and the EPA to make the final decision on a remedy.

  16. Quality and productivity drive innovation and improvement at United Technologies Aerospace Operations, Inc.

    Science.gov (United States)

    Jamar, L. G.

    1986-01-01

    Quality and innovation are the hallmarks of the national space program. In programs that preceded the Shuttle Program the emphasis was on meeting the risks and technical challenges of space with safety, quality, reliability, and success. At United Technologies Aerospace Operations, Inc. (UTAO), the battle has developed along four primary fronts. These fronts include programs to motivate and reward people, development and construction of optimized processes and facilities, implementation of specifically tailored management systems, and the application of appropriate measurement and control systems. Each of these initiatives is described. However, to put this quality and productivity program in perspective, UTAO and its role in the Shuttle Program are described first.

  17. Best management practices plan for the Lower East Fork Poplar Creek Operable Unit, Oak Ridge, Tennessee

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-04-01

    This plan was prepared in support of the Phase II Remedial Design Report (DOE/OR/01-1449&D1) and in accordance with requirements under CERCLA to present the plan for best management practices to be followed during the remediation. This document provides the Environmental Restoration Program with information about spill prevention and control, water quality monitoring, good housekeeping practices, sediment and erosion control measures, and inspections and environmental compliance practices to be used during Phase II of the remediation project for the Lower East Fork Poplar Creek Operable Unit.

  18. Remedial investigation/feasibility study work plan for the 100-BC-2 operable unit, Hanford Site, Richland, Washington

    Energy Technology Data Exchange (ETDEWEB)

    1993-05-01

    This work plan and attached supporting project plans establish the operable unit setting and the objectives, procedures, tasks, and schedule for conducting the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA) remedial investigation/feasibility study (RI/FS) for the 100-BC-2 operable unit in the 100 Area of the Hanford Site. The 100 Area is one of four areas at the Hanford Site that are on the US Environmental Protection Agency`s (EPA) National Priorities List under CERCLA. The 100-BC-2 operable unit is one of two source operable units in the 100-B/C Area (Figure ES-1). Source operable units are those that contain facilities and unplanned release sites that are potential sources of hazardous substance contamination. The 100-BC-2 source operable unit contains waste sites that were formerly in the 100-BC-2, 100-BC-3, and 100-BC-4 operable units. Because of their size and geographic location, the waste sites from these two operable units were added to 100-BC-2. This allows for a more efficient and effective investigation of the remaining 100-B/C Reactor area waste sites. The investigative approach to waste sites associated with the 100-BC-2 operable unit are listed in Table ES-1. The waste sites fall into three general categories: high priority liquid waste disposal sites, low priority liquid waste disposal sites, and solid waste burial grounds. Several sites have been identified as candidates for conducting an IRM. Two sites have been identified as warranting additional limited field sampling. The two sites are the 116-C-2A pluto crib, and the 116-C-2C sand filter.

  19. Logistics measurement and performance for United States-Mexican operations under NAFTA

    Energy Technology Data Exchange (ETDEWEB)

    Fawcett, S.E. [Michigan State Univ., East Lansing, MI (United States); Smith, S.R. [Brigham Young Univ., Laie, HI (United States)

    1995-12-01

    An empirical study utilizing a survey methodology was undertaken to explore the issues surrounding logistics performance under the recently enacted North American Free Trade Agreement (NAFTA). The study surveyed 524 senior level managers directly responsible for their strategic business units` operations involving Mexican production sharing. The study focused on what role Mexican production facilities take in the production process, relative technology level, planning activities, final destination of products, and what level of logistics performance was required to successfully operate. Some of the findings suggest a need to reevaluate current strategies to incorporate logistics support systems. Many benefits of true integration may have been overlooked since logistics was given a secondary position when strategies were formulated. Excessive tranportation and distribution costs may be lowered if logistics is given a higher emphasis in corporate decision making.

  20. Maintenance and operation of a hydroelectric unit of energy in a power system using virtual reality

    Energy Technology Data Exchange (ETDEWEB)

    de Sousa, Marcos Paulo Alves [Federal University of Para, Faculty of Engineering Computing, Augusto Correa Street, No. 1, Belem, Para (Brazil); Emilio Goeldi Museum, Service Data Processing Department, Perimetral Avenue No. 1901, Belem, Para (Brazil); Filho, Manoel Ribeiro; Nunes, Marcus Vinicius Alves; Lopes, Andrey da Costa [Federal University of Para, Faculty of Engineering Computing, Augusto Correa Street, No. 1, Belem, Para (Brazil)

    2010-07-15

    This paper presents a new approach to training for hydroelectric unit of energy (HUE) by using virtual reality Non-immersive techniques. The software offers two modules of training: maintenance and operation. The first module, maintenance, uses the learning approach based on practice and offers different training levels, divided into three modes: automatic, guided, and exploratory, in which these modes are accessed according to the acquired degree of knowledge by the trainee in relation to maintenance procedures. The second module, allows the trainee to visualize the operation of HUE during a certain event as the electromechanical dynamics of the turbine-generator assemblage in the virtual world by the visualization of several requisite conditions before the startup-shutdown procedure of HUE. (author)

  1. Overview of the Habitat Demonstration Unit Power System Integration and Operation at Desert RATS 2010

    Science.gov (United States)

    Colozza, Anthony J.; George, Pat; Gambrell, Ronnie; Chapman, Chris

    2013-01-01

    A habitat demonstration unit (HDU) was constructed at NASA Johnson Space Center (JSC) and designed by a multicenter NASA team led out of NASA Kennedy Space Center (KSC). The HDU was subsequently utilized at the 2010 Desert Research and Technology Studies (RATS) program held at the Black Point Lava Flow in Arizona. This report describes the power system design, installation and operation for the HDU. The requirements for the power system were to provide 120 VAC, 28 VDC, and 120 VDC power to the various loads within the HDU. It also needed to be capable of providing power control and real-time operational data on the load's power consumption. The power system had to be capable of operating off of a 3 phase 480 VAC generator as well as 2 solar photovoltaic (PV) power systems. The system operated well during the 2 week Desert RATS campaign and met all of the main goals of the system. The power system is being further developed to meet the future needs of the HDU and options for this further development are discussed.

  2. Light weight portable operator control unit using an Android-enabled mobile phone

    Science.gov (United States)

    Fung, Nicholas

    2011-05-01

    There have been large gains in the field of robotics, both in hardware sophistication and technical capabilities. However, as more capable robots have been developed and introduced to battlefield environments, the problem of interfacing with human controllers has proven to be challenging. Particularly in the field of military applications, controller requirements can be stringent and can range from size and power consumption, to durability and cost. Traditional operator control units (OCUs) tend to resemble laptop personal computers (PCs), as these devices are mobile and have ample computing power. However, laptop PCs are bulky and have greater power requirements. To approach this problem, a light weight, inexpensive controller was created based on a mobile phone running the Android operating system. It was designed to control an iRobot Packbot through the Army Research Laboratory (ARL) in-house Agile Computing Infrastructure (ACI). The hardware capabilities of the mobile phone, such as Wi- Fi communications, touch screen interface, and the flexibility of the Android operating system, made it a compelling platform. The Android based OCU offers a more portable package and can be easily carried by a soldier along with normal gear requirements. In addition, the one hand operation of the Android OCU allows for the Soldier to keep an unoccupied hand for greater flexibility. To validate the Android OCU as a capable controller, experimental data was collected evaluating use of the controller and a traditional, tablet PC based OCU. Initial analysis suggests that the Android OCU performed positively in qualitative data collected from participants.

  3. Tracheotomy in Pediatric Patients: In Operating Room or Intensive Care Unit?

    Directory of Open Access Journals (Sweden)

    Umut Kaygusuz

    2014-08-01

    Full Text Available Introduction: The morbidity and mortality rates of tracheotomy are higher in the pediatric population because the incision is small and the trachea is more prone to surgical trauma. Tracheotomy procedure is mostly performed in operating room in most institutions. The aim of the study is to compare the outcomes of tracheotomy procedures between intensive care unit (ICU and operating room (OR in terms of pitfalls, complications and family preferences. Materials and Methods: In between June 2012 and July 2013, at a single institution, 39 patients were prospectively analyzed for age, gender, primary pathology, tracheotomy indications, location of operation, the duration of family consent, perioperative complications and presence of decanulation. Results: Male/female ratio was 20/19. Mean age was 49.9±52.5 (4-204 months. Tracheotomy procedure was performed in OR in 19 patients (45% and in ICU in 20 (54.5% patients. There was no statistically significant difference between groups in terms of complications (OR-48.7%, ICU-51.3%. The time of informed consent was significantly shorter in ICU patients. Conclusions: There is no significant difference in terms of safety for tracheotomy procedure in ICU or OR. Parents give approval to a bedside invasive procedure faster. The words ‘Surgery’ and ‘Operating room’ can easily confuse the parents, extend the duration for endolaryngeal intubation, and increase the cost and labour loss.

  4. Steering quantum-memory-assisted entropic uncertainty under unital and nonunital noises via filtering operations

    Science.gov (United States)

    Huang, Ai-Jun; Shi, Jia-Dong; Wang, Dong; Ye, Liu

    2017-02-01

    In this work, we investigate the dynamic features of the entropic uncertainty for two incompatible measurements under local unital and nonunital channels. Herein, we choose Pauli operators σ _x and σ _z as a pair of observables of interest measuring on particle A, and the uncertainty can be predicted when particle A is entangled with quantum memory B. We explore the dynamics of the uncertainty for the measurement under local unitary (phase-damping) and nonunitary (amplitude-damping) channels, respectively. Remarkably, we derive the entropic uncertainty relation under three different kinds of measurements of Pauli-observable pair under various realistic noisy environments; it has been found that the entropic uncertainty has the same tendency of its evolution during the AD and PD channel when we choose σ _x and σ _y measurement. Besides, we find out that the entropic uncertainty will have an optimal value if one chooses σ _x and σ _z as the measurement incompatibility, comparing with others. Furthermore, in order to reduce the entropic uncertainty in noisy environment, we propose an effective strategy to steer the amount by means of implementing a filtering operation on the particle under the two types of channels, respectively. It turns out that this operation can greatly reduce the entropic uncertainty by modulation of the operation strength. Thus, our investigations might offer an insight into the dynamics and steering of the entropic uncertainty in an open system.

  5. Do different populations of Aphanius dispar in Southern Iran form Operational Taxonomic Units (OUTs?

    Directory of Open Access Journals (Sweden)

    Azad Teimori

    2015-10-01

    Full Text Available Deciphering the exact fundamental relations of morphological differentiation among isolated populations of animal species is generally difficult. Usually changes in morphology are resulted from adaptation to different environmental conditions (ecoplasticity or represent an expression of genetic differences and/or gene pool pauperization, and in most instances, however, changes in morphology are the result of the interplay between environmental factors and genetic plasticity. In this study, the morphology and molecular phylogenies of common tooth-carp populations (Aphanius dispar were studied in three basins in Southern part of Iran to discuss an important aspect relate to the question whether morphologically differentiated populations of a single species function as Operational Taxonomic Units. All morphological analyses were revealed significant and strong morphological differentiation between the populations that corresponds well with their zoogeography and their molecular phylogeny in geographically isolated basins. Therefore, it can be concluded that when the interaction between gene flow among populations and natural selection is resulted owing to a long evolutionary history, then the observed morphological differences can be functioned as different Operational Taxonomic Units (OTUs in subspecies or even species levels. In addition, biological characteristics of the A. dispar, its high tolerance, geological and ecological conditions in Southern Iran are the main factors that increase chance of reproductive isolation and genetic diversity in this region.

  6. Explicit isospectral flows associated to the AKNS operator on the unit interval. II

    Science.gov (United States)

    Amour, Laurent

    2012-10-01

    Explicit flows associated to any tangent vector fields on any isospectral manifold for the AKNS operator acting in L2 × L2 on the unit interval are written down. The manifolds are of infinite dimension (and infinite codimension). The flows are called isospectral and also are Hamiltonian flows. It is proven that they may be explicitly expressed in terms of regularized determinants of infinite matrix-valued functions with entries depending only on the spectral data at the starting point of the flow. The tangent vector fields are decomposed as ∑ξkTk where ξ ∈ ℓ2 and the Tk ∈ L2 × L2 form a particular basis of the tangent vector spaces of the infinite dimensional manifold. The paper here is a continuation of Amour ["Explicit isospectral flows for the AKNS operator on the unit interval," Inverse Probl. 25, 095008 (2009)], 10.1088/0266-5611/25/9/095008 where, except for a finite number, all the components of the sequence ξ are zero in order to obtain an explicit expression for the isospectral flows. The regularized determinants induce counter-terms allowing for the consideration of finite quantities when the sequences ξ run all over ℓ2.

  7. Current Conditions Risk Assessment for the 300-FF-5 Groundwater Operable Unit

    Energy Technology Data Exchange (ETDEWEB)

    Miley, Terri B.; Bunn, Amoret L.; Napier, Bruce A.; Peterson, Robert E.; Becker, James M.

    2007-11-01

    This report updates a baseline risk assessment for the 300 Area prepared in 1994. The update includes consideration of changes in contaminants of interest and in the environment that have occurred during the period of interim remedial action, i.e., 1996 to the present, as well as the sub-regions, for which no initial risk assessments have been conducted. In 1996, a record of decision (ROD) stipulated interim remedial action for groundwater affected by releases from 300 Area sources, as follows: (a) continued monitoring of groundwater that is contaminated above health-based levels to ensure that concentrations continue to decrease, and (b) institutional controls to ensure that groundwater use is restricted to prevent unacceptable exposure to groundwater contamination. In 2000, the groundwater beneath the two outlying sub-regions was added to the operable unit. In 2001, the first 5-year review of the ROD found that the interim remedy and remedial action objectives were still appropriate, although the review called for additional characterization activities. This report includes a current conditions baseline ecological and human health risk assessment using maximum concentrations in the environmental media of the 300-FF-5 Operable Unit and downstream conditions at the City of Richland, Washington. The scope for this assessment includes only current measured environmental concentrations and current use scenarios. Future environmental concentrations and future land uses are not considered in this assessment.

  8. Phase I and II feasibility study report for the 300-FF-5 operable unit

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1993-12-31

    The purpose of this Phase I/II feasibility study is to assemble and screen a list of alternatives for remediation of the 300-FF-5 operable site on the Hanford Reservation. This screening is based on information gathered in the Phase I Remedial Investigation (RI) and on currently available information on remediation technologies. The alternatives remaining after screening provide a range of response actions for remediation. In addition, key data needs are identified for collection during a Phase II RI (if necessary). This Phase I/II FS represents a primary document as defined by the Tri-Party Agreement, but will be followed by a Phase III FS that will further develop the alternatives and provide a detailed evaluation of them. The following remedial action objectives were identified for the 300-FF-5 operable unit: Limit current human exposure to contaminated groundwater in the unit; Limit discharge of contaminated groundwater to the Columbia River; Reduce contaminant concentrations in groundwater below acceptable levels by the year 2018.

  9. Interprofessional rhetoric and operational realities: an ethnographic study of rounds in four intensive care units.

    Science.gov (United States)

    Paradis, Elise; Leslie, Myles; Gropper, Michael A

    2016-10-01

    Morning interprofessional rounds (MIRs) are used in critical care medicine to improve team-based care and patient outcomes. Given existing evidence of conflict between and dissatisfaction among rounds participants, this study sought to better understand how the operational realities of care delivery in the intensive care unit (ICU) impact the success of MIRs. We conducted a year-long comparative ethnographic study of interprofessional collaboration and patient and family involvement in four ICUs in tertiary academic hospitals in two American cities. The study included 576 h of observation of team interactions, 47 shadowing sessions and 40 clinician interviews. In line with best practices in ethnographic research, data collection and analysis were done iteratively using the constant comparative method. Member check was conducted regularly throughout the project. MIRs were implemented on all units with the explicit goals of improving team-based and patient-centered care. Operational conditions on the units, despite interprofessional commitment and engagement, appeared to thwart ICU teams from achieving these goals. Specifically, time constraints, struggles over space, and conflicts between MIRs' educational and care-plan-development functions all prevented teams from achieving collaboration and patient-involvement. Moreover, physicians' de facto control of rounds often meant that they resembled medical rounds (their historical predecessors), and sidelined other providers' contributions. This study suggests that the MIRs model, as presently practiced, might not be well suited to the provision of team-based, patient-centered care. In the interest of interprofessional collaboration, of the optimization of clinicians' time, of high-quality medical education and of patient-centered care, further research on interprofessional rounds models is needed.

  10. Inflammatory characteristics of distinct abdominal adipose tissue depots relate differently to metabolic risk factors for cardiovascular disease Distinct fat depots and vascular risk factors

    NARCIS (Netherlands)

    Kranendonk, Mariette E. G.; van Herwaarden, Joost A.; Stupkova, Tereza; de Jager, Wilco; Vink, Aryan; Moll, Frans L.; Kalkhoven, Eric; Visseren, Frank L. J.

    2015-01-01

    Objective: Abdominal obesity is associated with insulin resistance and metabolic syndrome. However, specific contributions of distinct adipose tissue (AT) depots to metabolic complications of obesity are still unclear. In this study, the inflammatory profile of four distinct abdominal AT-depots and

  11. Record of Decision for the Rocky Mountain Arsenal On-Post Operable Unit in southern Adams County, Commerce City, Colorado.

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This Record of Decision (ROD) presents the selected remedial action for the Rocky Mountain Arsenal (RMA) On-Post Operable Unit in southern Adams County (east of...

  12. A descriptive survey of management and operations at selected sports medicine centers in the United States.

    Science.gov (United States)

    Olsen, D

    1996-11-01

    No uniform guidelines for operations or accreditation standards for sports medicine center were available and, at the time of this study, little information on the management and operation of sports medicine centers was available in the literature. The purpose of the study was to determine the management structure and function of selected sports medicine centers in the United States. Questionnaires were mailed to 200 randomly selected centers throughout the United State from a directory of sports medicine centers published in Physician and Sportsmedicine (1992) to gather descriptive information on eight areas, including 1) general background, 2) staffing, 3) services, facilities, and equipment, 4) billing, collections, and revenue, 5) clientele, caseloads, and referrals, 6) ownership and financing, 7) school and club outreach contracts, and 8) marketing strategies and future trends. A total of 71 surveys (35.5%) were returned in the allotted time frame. Data were analyzed using ranges, means, medians, modes, and percentages. Results yielded several conclusions about sports medicine centers. Nearly all (93%) of the centers employed physical therapists; physical therapists were clinical directors at 70.2% of centers; orthopaedists were most often medical directors; rehabilitation was the most frequently offered service (93%); physical therapy produced the highest revenue; sports injuries accounted for a mean 34.5% of patients, who were mostly recreational or high school athletes between 13-60 years of age; primary shareholders were most often physical therapists or physicians; most were involved in outreach services for schools; marketing strategies primarily involved communication with referral sources; and managed care was identified most frequently as a trend affecting the future of sports medicine centers. Findings identified common aspects of sports medicine centers and may assist in establishing guidelines for operations or accreditation of sports medicine

  13. Operational Ensemble River Forecasting in the United States and Australia: Practices and Challenges

    Science.gov (United States)

    Pagano, T. C.

    2012-04-01

    Operational river forecasts have been long produced to support water resources management in the United States and Australia. These forecasts cover a range of timescales from flash flooding (e.g. minutes to hours ahead) to seasonal (e.g. months ahead) and are generated by a range of statistical (e.g. regression-based) and dynamical (e.g. rainfall-runoff) model based techniques. Forecast uncertainty is commonly estimated operationally by using an ensemble of future precipitation scenarios and/or a measure of historical model error. Retrospective ensemble forecasting and the use of reforecasts for bias-adjustment and post-processing have become popular research topics and a few successful demonstration projects exist in both countries. Practical methods of post-processing, such as ensemble dressing, have been used to improve the probabilistic reliability of forecasts. The translation of predictions of probability distributions of streamflow into temporally and spatially consistent ensemble hydrographs remains an area for further development. However, probabilistic forecast communication and use remains a stumbling block for many. Furthermore, ensemble generation and post-processing typically require completely automated systems, making it difficult for humans to contribute their expertise to the forecasting process. This talk draws on ten years of experience as an operational forecaster with the US Department of Agriculture and as a developer of short-term flood forecasting systems to support the Australian Bureau of Meteorology.

  14. Master Environmental Plan: Fort Wingate Depot Activity, Gallup, New Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Biang, C.A.; Yuen, C.R.; Biang, R.P.; Antonopoulos, A.A.; Ditmars, J.D.

    1990-12-01

    The master environmental plan is based on an environmental assessment of the areas requiring environmental evaluation (AREEs) at Fort Wingate Depot Activity near Gallup, New Mexico. The Fort Wingate Depot Activity is slated for closure under the Base Closure and Realignment Act, Public Law 100--526. The MEP assesses the current status, describes additional data requirements, recommends actions for the sites, and establishes a priority order for actions. The plan was developed so that actions comply with hazardous waste and water quality regulations of the State of New Mexico and applicable federal regulations. It contains a brief history of the site, relevant geological and hydrological information, and a description of the current status for each AREE along with a discussion of the available site-specific data that pertain to existing or potential contamination and the impact on the environment. 35 refs., 27 figs., 23 tabs.

  15. A Formula for the Units to Satisfy an Operation's Desired Rate of Return in CVP Analysis--A Conceptual Approach

    Science.gov (United States)

    Anderson, Johann A.; Leese, Wallace R.

    2016-01-01

    A common formula presented in many managerial- and cost-accounting textbooks makes possible the determination of the quantity of units which must be produced and sold to generate a desired dollar-amount of operating income. This article addresses the question "What formula can be used to determine the quantity of units needed to yield a…

  16. 40 CFR Table 6 to Subpart Ppp of... - Process Vents From Continuous Unit Operations-Monitoring, Recordkeeping, and Reporting Requirements

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 11 2010-07-01 2010-07-01 true Process Vents From Continuous Unit Operations-Monitoring, Recordkeeping, and Reporting Requirements 6 Table 6 to Subpart PPP of Part 63... Subpart PPP of Part 63—Process Vents From Continuous Unit Operations—Monitoring, Recordkeeping, and...

  17. 40 CFR 60.1690 - What are the operating practice requirements for my municipal waste combustion unit?

    Science.gov (United States)

    2010-07-01

    ... requirements for my municipal waste combustion unit? 60.1690 Section 60.1690 Protection of Environment... SOURCES Emission Guidelines and Compliance Times for Small Municipal Waste Combustion Units Constructed on or Before August 30, 1999 Model Rule-Good Combustion Practices: Operating Requirements § 60.1690 What...

  18. [Treatment of Adult Schizophrenic Patients With Depot Antipsychotics].

    Science.gov (United States)

    Jaramillo González, Luis Eduardo; Gómez Restrepo, Carlos; García Valencia, Jenny; de la Hoz Bradford, Ana María; Ávila-Guerra, Mauricio; Bohórquez Peñaranda, Adriana

    2014-01-01

    To determine the indications of long-acting antipsychotic injection and what its effectiveness and safety in adult patients with schizophrenia during the treatment maintenance phase. A clinical practice guideline was elaborated under the parameters of the Methodological Guide of the Ministerio de Salud y Protección Social to identify, synthesize and evaluate the evidence and make recommendations about the treatment and follow-up of adult patients with schizophrenia. The evidence of NICE guide 82 was adopted and updated. The evidence was presented to the Guideline Developing Group and recommendations, employing the GRADE system, were produced. The literature review shows that the evidence has moderate to low quality. 8 articles were used. The risk of relapse was lower with depot risperidone and paliperidone palmitate when compared with placebo. For the risk of hospitalizations comparing depot antipsychotics (APD) versus oral AP, the result is inconclusive. Globally the second-generation APD had a lower risk of discontinuation when compared with placebo. The second generation AP had higher risk of extrapyramidal syndromes than placebo, as in the use of antiparkinsonian. The comparison of second-generation AP injections versus placebo showed an increased risk of early weight gain. The use of depot antipsychotics in the maintenance phase of adult patients diagnosed with schizophrenia is recommended if there is no adherence to oral antipsychotics as the patient's preference. It is not recommended depot antipsychotics in the acute phase of schizophrenia in adults. Copyright © 2014 Asociación Colombiana de Psiquiatría. Publicado por Elsevier España. All rights reserved.

  19. Buserelin-depot in the treatment of prostate cancer

    Directory of Open Access Journals (Sweden)

    G. P. Kolesnikov

    2015-01-01

    Full Text Available The high incidence of prostate cancer (PC and the considerably wide use of hormone therapy for its treatment as an individual modalityfor its advanced forms (Т3–Т4, N1, M1, recurrences, and progression after local treatments (radical prostatectomy, radiation therapy and for combined treatment as neoadjuvant and adjuvant therapies determine the importance of a sufficient range of hormonal drugs at an urologic oncologist’s disposal. Among the luteinizing hormone-releasing hormone (LHRH agonists, there is rather long-known Buserelin made in Russia, the clinical efficacy of which is highly competitive with foreign analogs. The paper presents the results of a 3-month trial of the efficiency and safety of Buserelin depot treatment in 20 patients aged 53 to 87 years with morphologically verified PC. The patients with PC showed a gradual decrease in the mean values of prostate-specific antigen (PCA from81.2 to 27.8 and 23.0 ng / ml at 2 and 3 months of Buserelin depot therapy, respectively. The performed therapy could achieve reductions in testosterone levels from 168 ng / dl at baseline to 21 and 19.8 ng / dl postcastration at 1 and 3 months of the therapy.All the patients tolerated Buserelin depot therapy without having clinically significant adverse reactions. The most common complaints were hyperhidrosis and hot flushes, which are typical of all LHRH agonists and which are not marked in the treatment with other drugs of this group.Conclusion. Buserelin depot 3.75 mg is a highly effective Russian drug to treat hormone-dependent PC. Its administration causes a reduction in PSA levels and ensures a steady decline in serum testosterone concentrations to the postcastration level without causing serious side effects. The findings do not differ from those when foreign LHRH analogues are used.

  20. An Organizational Analysis of Marine Corps Recruit Depot, San Diego

    Science.gov (United States)

    2003-03-01

    generations, e.g., Gen-X and millennials . e. Process/Subsystems This design factor addresses: 1. Financial Management, Measurement and Controls...As the RTR CO says, “the beauty of this place is just basic Marine Corps leadership. MOS regardless.”70 More specifically, it’s “leadership...The fact that we can question what we are doing is beautiful .”74 He has begun a planning culture within Depot staff offices. Such thinking in

  1. The Home Depot Upgrades its Corporate Building Prototype

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2013-03-01

    The Home Depot partnered with the Department of Energy (DOE) to develop and implement solutions to build new, low-energy buildings that are at least 50% below Standard 90.1-2007 of the American Society of Heating, Refrigerating, and Air-Conditioning Engineers (ASHRAE), the American National Standards Institute (ANSI), and the Illuminating Engineering Society of North America (IESNA) as part of DOE’s Commercial Building Partnerships (CBP) Program.

  2. Lanreotide Depot: An Antineoplastic Treatment of Carcinoid or Neuroendocrine Tumors

    OpenAIRE

    Wolin, Edward M.; Manon, Amandine; Chassaing, Christophe; Lewis, Andy; Bertocchi, Laurent; Richard,Joel; Phan,Alexandria T

    2016-01-01

    Purpose Peptide drugs for antineoplastic therapies usually have low oral bioavailability and short in vivo half-lives, requiring less preferred delivery methods. Lanreotide depot is a sustained-release somatostatin analog (SSA) formulation produced via an innovative peptide self-assembly method. Lanreotide is approved in the USA and Europe to improve progression-free survival (PFS) in patients with unresectable gastroenteropancreatic neuroendocrine tumors (GEP-NETs) and also approved in Europ...

  3. The United Nations Standing Force a Qualitative Analysis of Strategic and Operational Options for the United States

    Science.gov (United States)

    1993-06-01

    Council, has done .ch community...But, as much as the United Nations has done, it can do much more." Chaiaiing Times As the Bob Dylan song goes, "The...to our nation’s defense well into the twenty-first century. When Bob Dylan’s song was popular, it was also relevant. At that time, the United States

  4. AUTOMATED GUIDED VEHICLE (AGV SYSTEMS AND ROUTING PROBLEM IN DEPOT MAINTENANCE

    Directory of Open Access Journals (Sweden)

    Fatih YİĞİT

    2003-02-01

    Full Text Available When full automation is realized in factory automation, material handing systems (MHS have a fairly important role. The most technological development among MHS's has been concentrated on Automated Guided Vehicle (AGV systems. An AGV is an unmanned vehicle capable of following an external guidance signal to deliver a unit load from destination to destination. Nowadays, there are a lot of applications lie along service sector to industrial sector because of flexibilities of AGVs. In this study, these subjects have been applied on the Army Aviation Depot Maintenance where aircraft's and aircraft parts can be maintained and overhauled is an application fields of AGV, requiring AGV numbers and AGV routing. The AGV routing problem and traveling sales person (TSP problems are identical problems; where the AGV routing problem is formulated as a zero one integer programming. Examples are presented to demonstrate the approach and LINGO has been used to solve the example.

  5. Medical Cosmopolitanism in Global Dubai: A Twenty-first-century Transnational Intracytoplasmic Sperm Injection (ICSI) Depot.

    Science.gov (United States)

    Inhorn, Marcia C

    2017-03-01

    Dubai-one of the seven United Arab Emirates and the Middle East's only "global city"-is gaining a reputation as a transnational medical tourism hub. Characterized by its "medical cosmopolitanism," Dubai is now attracting medical travelers from around the world, some of whom are seeking assisted conception. Dubai is fast becoming known as a new transnational "reprohub" for intracytoplasmic sperm injection (ICSI), the variant of in vitro fertilization designed to overcome male infertility. Based on ethnographic research conducted in one of the country's most cosmopolitan clinics, this article explores the ICSI treatment quests of infertile men coming to Dubai from scores of other nations. The case of an infertile British-Moroccan man is highlighted to demonstrate why ICSI is a particularly compelling "masculine hope technology" for infertile Muslim men. Thus, Muslim men who face barriers to ICSI access in their home countries may become "reprotravelers" to Dubai, an emergent ICSI depot.

  6. Evaluation of the operational efficiency of pacifying police units in the state of Rio de Janeiro

    Directory of Open Access Journals (Sweden)

    Igor Rosa Dias de Jesus

    2014-05-01

    Full Text Available The Pacification Police Unit (UPP is a new model for public security and policing, aimed at ensuring local security and, above all, reduce, or even, extinguish violent crime linked to drug trafficking, and approach people and police. The purpose of this article is measuring the operational efficiency of all UPPs installed in the state of Rio de Janeiro by the beginning of 2011 by Data Envelopment Analysis (DEA. For this, it was used the CCR model – input-oriented – developed by Charnes, Cooper and Rhodes, which allows an objective assessment of the overall efficiency, identifying the sources of inefficiencies and the needed targets to achieve the efficiency in each UPP. The results converge to a reduction of the amount of policemen in all communities out of the efficiency frontier.

  7. Technical work plan for Surface Impoundments Operable Unit engineering support studies

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-11-01

    This document provides a comprehensive work plan which, when utilized as a data collection guide for field activities, will provide the necessary information required to complete a report on geotechnical properties of the sediments contained in the Surface Impoundments Operable Unit at Oak Ridge National Laboratory in Oak Ridge, Tennessee. Detailed guidance is provided for the following activities: collection of samples from the impoundments; compressive strength testing of the raw sediments; compressive strength testing of the structurally modified (lime and cement additives) sediments; testing for sediment physical properties and settling rates; testing for sediment dewatering characteristics; testing for radiation activity during the field work; testing for polymer additions that may enhance settling. The work plan additionally provides guidance and examples for the preparation of documents necessary to establish readiness for safe and satisfactory performance of the field activities. An outline for the format requested for a report of these data is also provided.

  8. 100-OL-1 Operable Unit Field Portable X-Ray Fluorescence (XRF) Analyzer Pilot Study Plans

    Energy Technology Data Exchange (ETDEWEB)

    Bunn, Amoret L. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Fritz, Brad G. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Wellman, Dawn M. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2014-07-01

    A pilot study is being conducted to support the approval of the Remedial Investigation/Feasibility Study (RI/FS) Work Plan to evaluate the 100-OL-1 Operable Unit (OU) pre-Hanford orchard lands. Based on comments received by the U.S. Environmental Protection Agency (EPA) and Washington State Department of Ecology, the pilot study will evaluate the use of field portable X-ray fluorescence (XRF) spectrometry measurements for evaluating lead and arsenic concentrations on the soil surface as an indicator of past use of lead arsenate pesticide residue in the OU. The work will be performed in the field during the summer of 2014, and assist in the planning for the characterization activities in the RI/FS.

  9. Eielson Air Force Base operable unit 2 and other areas record of decision

    Energy Technology Data Exchange (ETDEWEB)

    Lewis, R.E.; Smith, R.M.

    1994-10-01

    This decision document presents the selected remedial actions and no action decisions for Operable Unit 2 (OU2) at Eielson Air Force Base (AFB), Alaska, chosen in accordance with state and federal regulations. This document also presents the decision that no further action is required for 21 other source areas at Eielson AFB. This decision is based on the administrative record file for this site. OU2 addresses sites contaminated by leaks and spills of fuels. Soils contaminated with petroleum products occur at or near the source of contamination. Contaminated subsurface soil and groundwater occur in plumes on the top of a shallow groundwater table that fluctuates seasonally. These sites pose a risk to human health and the environment because of ingestion, inhalation, and dermal contact with contaminated groundwater. The purpose of this response is to prevent current or future exposure to the contaminated groundwater, to reduce further contaminant migration into the groundwater, and to remediate groundwater.

  10. Designing User Interfaces for Smart-Applications for Operating Rooms and Intensive Care Units

    Science.gov (United States)

    Kindsmüller, Martin Christof; Haar, Maral; Schulz, Hannes; Herczeg, Michael

    Today’s physicians and nurses working in operating rooms and intensive care units have to deal with an ever increasing amount of data. More and more medical devices are delivering information, which has to be perceived and interpreted in regard to patient status and the necessity to adjust therapy. The combination of high information load and insufficient usability creates a severe challenge for the health personnel with respect to proper monitoring of these devices respective to acknowledging alarms and timely reaction to critical incidents. Smart Applications are a new kind of decision support systems that incorporate medical expertise in order to help health personnel in regard to diagnosis and therapy. By means of a User Centered Design process of two Smart Applications (anaesthesia monitor display, diagnosis display), we illustrate which approach should be followed and which processes and methods have been successfully applied in fostering the design of usable medical devices.

  11. Performance of ESPs operating downstream from spray-drying desulphurisation units

    Energy Technology Data Exchange (ETDEWEB)

    Ollero, P.; Canadas, L.; Salvador, L. [Escuela Superior de Ingenieros Industrials, Sevilla (Spain)] [and others

    1995-06-01

    This paper summarizes data from a Spray Dryer/ESP pilot plant located at the Los Barrios Coal Power Plant (Cadiz, Spain). A series of tests has been conducted to evaluate the performance of an existing ESP operating downstream from a spray dryer in a retrofit application. A factorial design of experiments with two SO{sub 2} levels, two flyash load levels, three Ca/S ratios and three sulfur removal efficiencies, was run during a six-month experimental programme. A global and a field-by-field analysis of the performance of the pilot ESP has shown that the desulphurisation unit enhances ESP efficiency and reduces the emission level. No evidence of electrical dust reentrainment has been found.

  12. Analysis of hot spots in boilers of organic Rankine cycle units during transient operation

    DEFF Research Database (Denmark)

    Benato, A.; Kærn, Martin Ryhl; Pierobon, Leonardo

    2015-01-01

    This paper is devoted to the investigation of critical dynamic events causing thermochemical decompositionof the working fluid in organic Rankine cycle power systems. The case study is the plant of an oiland gas platform where one of the three gas turbines is combined with an organic Rankine cycle...... unit toincrease the overall energy conversion efficiency.The dynamic model of the plant is coupled with a one-dimensional model of the once-through boilerfed by the exhaust thermal power of the gas turbine. The heat exchanger model uses a distributedcross-flow physical topology and local correlations...... and fluid decomposition. It is demonstrated thatthe use of a spray attemperator can mitigate the problems of local overheating of the organic compound.As a practical consequence, this paper provides guidelines for safe and reliable operation of organicRankine cycle power modules on offshore installations....

  13. Development and Evaluation of the Habitat Demonstration Unit Medical Operations Workstation and Opportunities for Future Research

    Science.gov (United States)

    Howard, Robert L., Jr.

    2012-01-01

    As NASA develops missions to leave Earth orbit and explore distant destinations (Mars, Moon, Asteroids) it is necessary to rethink human spaceflight paradigms in the life sciences. Standards developed for low earth orbit human spaceflight may not be fully applicable and in-space research may be required to develop new standards. Preventative and emergency medical care may require new capabilities never before used in space. Due to spacecraft volume limitations, this work area may also be shared with various animal and plant life science research. This paper explores the prototype Medical Operations Workstation within the NASA Habitat Demonstration Unit and discusses some of the lessons learned from field analogue missions involving the workstation. Keywords: Exploration, medical, health, crew, injury emergency, biology, animal, plant, science, preventative, emergency.

  14. Thermo-physical performance prediction of the KSC Ground Operation Demonstration Unit for liquid hydrogen

    Science.gov (United States)

    Baik, J. H.; Notardonato, W. U.; Karng, S. W.; Oh, I.

    2015-12-01

    NASA Kennedy Space Center (KSC) researchers have been working on enhanced and modernized cryogenic liquid propellant handling techniques to reduce life cycle costs of propellant management system for the unique KSC application. The KSC Ground Operation Demonstration Unit (GODU) for liquid hydrogen (LH2) plans to demonstrate integrated refrigeration, zero-loss flexible term storage of LH2, and densified hydrogen handling techniques. The Florida Solar Energy Center (FSEC) has partnered with the KSC researchers to develop thermal performance prediction model of the GODU for LH2. The model includes integrated refrigeration cooling performance, thermal losses in the tank and distribution lines, transient system characteristics during chilling and loading, and long term steady-state propellant storage. This paper will discuss recent experimental data of the GODU for LH2 system and modeling results.

  15. Experience of operation of the gas turbine units in Russky Island

    Directory of Open Access Journals (Sweden)

    Bibikov Dmitry

    2017-01-01

    Full Text Available In the present article, the heat and power supply system based on the distributed cogeneration and created as part of the APEC Summit and development of the southern Far East is considered. A brief review of the experience of operating the gas turbine units of the Co-generation plant in the Russky Island is given. The output of the heat energy over 2015 reached 142.228 thousands Gcal which is larger than that in 2014 by 18.8 %. The specific reference fuel consumption for electric supply was 272.4 g/(kW*h while for heat supply – 195.8 kg/Gcal. In spite of partial load of the stations with regard to electric and heat energy (volumes of consumptions by the connected consumers is less than designed loads, the indices of reference fuel consumption suggest the efficiency of the generation equipment of co-generation plant.

  16. 77 FR 50541 - STP Nuclear Operating Company, South Texas Project, Units 1 and 2; Application for Amendment to...

    Science.gov (United States)

    2012-08-21

    ... COMMISSION STP Nuclear Operating Company, South Texas Project, Units 1 and 2; Application for Amendment to... of STP Nuclear Operating Company (the licensee) to withdraw its application dated June 2, 2011 (ADAMS... ``Begin Web- based ADAMS Search.'' For problems with ADAMS, please contact the NRC's Public Document...

  17. 78 FR 45987 - Vogtle Electric Generating Station, Units 3 and 4; Southern Nuclear Operating Company; Change to...

    Science.gov (United States)

    2013-07-30

    ... COMMISSION Vogtle Electric Generating Station, Units 3 and 4; Southern Nuclear Operating Company; Change to... COLs were issued to Southern Nuclear Operating Company, Inc., and Georgia Power Company, Oglethorpe... Search.'' For problems with ADAMS, please contact the NRC's Public Document Room (PDR) reference staff...

  18. 78 FR 45989 - Vogtle Electric Generating Station, Units 3 and 4; Southern Nuclear Operating Company; Change to...

    Science.gov (United States)

    2013-07-30

    ... COMMISSION Vogtle Electric Generating Station, Units 3 and 4; Southern Nuclear Operating Company; Change to... COLs were issued to Southern Nuclear Operating Company, Inc., and Georgia Power Company, Oglethorpe..., select ``ADAMS Public Documents'' and then select ``Begin Web-based ADAMS Search.'' For problems...

  19. Operation planning studies for the integration of the 60 Hz Itaipu units in the Brazilian interconnected system

    Energy Technology Data Exchange (ETDEWEB)

    Chipp, H.J.; Oliveira, J.C.C. [ELETROBRAS, Rio de Janeiro, RJ (Brazil); Correa, L.R.A. [FURNAS, Rio de Janeiro, RJ (Brazil); Mendonca, W.C.; Marchi, R.D. [Itaipu Binacional, Foz do Iguacu, PR (Brazil); Botelho, M.J. [ELETROSUL, Curitiba, PR (Brazil)

    1987-12-31

    This paper describes the operation planning studies necessary to interconnect the first two 60 Hz generator units of the Itaipu power plant to the Brazilian interconnected system. The criteria, main problems identified and operative solutions encountered are presented in this paper. 10 refs., 4 figs., 5 tabs.

  20. 78 FR 37584 - U.S. Steel Tubular Products, Inc., Mckeesport Tubular Operations Division, Subsidiary of United...

    Science.gov (United States)

    2013-06-21

    ... Employment and Training Administration U.S. Steel Tubular Products, Inc., Mckeesport Tubular Operations Division, Subsidiary of United States Steel Corporation, Mckeesport, Pennsylvania; Notice of Amended... workers of U.S. Steel Tubular Products, McKeesport Tubular Operations Division, a subsidiary of...

  1. Population pharmacokinetic modeling of a subcutaneous depot for GnRH antagonist degarelix

    DEFF Research Database (Denmark)

    Tornøe, Christoffer Wenzel; Agersø, Henrik; Nielsen, Henrik Aalborg;

    Purpose. The objective of this study is to develop a population pharmacokinetic (PK) model that describes the subcutaneous (SC) depot formation of gonadotropin-releasing hormone (GnRH) antagonist degarelix, which is being developed for treatment of prostate cancer, exhibiting dose-volume and dose...... depot model describes the PK profile of GnRH antagonist degarelix. This modeling approach might also be applicable for other depot-formulated drugs exhibiting complex PK profiles....

  2. Population Pharmacokinetic Modeling of a Subcutaneous Depot for GnRH Antagonist Degarelix

    DEFF Research Database (Denmark)

    Tornøe, Christoffer Wenzel; Agersø, Henrik; Nielsen, Henrik Aalborg;

    2004-01-01

    Purpose. The objective of this study is to develop a population pharmacokinetic (PK) model that describes the subcutaneous (SC) depot formation of gonadotropin-releasing hormone ( GnRH) antagonist degarelix, which is being developed for treatment of prostate cancer, exhibiting dose-volume and dose...... depot model describes the PK profile of GnRH antagonist degarelix. This modeling approach might also be applicable for other depot-formulated drugs exhibiting complex PK profiles....

  3. Population Pharmacokinetic Modeling of a Subcutaneous Depot for GnRH Antagonist Degarelix

    DEFF Research Database (Denmark)

    Tornøe, Christoffer Wenzel; Agersø, Henrik; Nielsen, Henrik Aalborg

    2004-01-01

    Purpose. The objective of this study is to develop a population pharmacokinetic (PK) model that describes the subcutaneous (SC) depot formation of gonadotropin-releasing hormone ( GnRH) antagonist degarelix, which is being developed for treatment of prostate cancer, exhibiting dose-volume and dose...... depot model describes the PK profile of GnRH antagonist degarelix. This modeling approach might also be applicable for other depot-formulated drugs exhibiting complex PK profiles....

  4. Ecological consistency of SSU rRNA-based operational taxonomic units at a global scale.

    Directory of Open Access Journals (Sweden)

    Thomas S B Schmidt

    2014-04-01

    Full Text Available Operational Taxonomic Units (OTUs, usually defined as clusters of similar 16S/18S rRNA sequences, are the most widely used basic diversity units in large-scale characterizations of microbial communities. However, it remains unclear how well the various proposed OTU clustering algorithms approximate 'true' microbial taxa. Here, we explore the ecological consistency of OTUs--based on the assumption that, like true microbial taxa, they should show measurable habitat preferences (niche conservatism. In a global and comprehensive survey of available microbial sequence data, we systematically parse sequence annotations to obtain broad ecological descriptions of sampling sites. Based on these, we observe that sequence-based microbial OTUs generally show high levels of ecological consistency. However, different OTU clustering methods result in marked differences in the strength of this signal. Assuming that ecological consistency can serve as an objective external benchmark for cluster quality, we conclude that hierarchical complete linkage clustering, which provided the most ecologically consistent partitions, should be the default choice for OTU clustering. To our knowledge, this is the first approach to assess cluster quality using an external, biologically meaningful parameter as a benchmark, on a global scale.

  5. Simulation of operational processes in hospital emergency units as lean healthcare tool

    Directory of Open Access Journals (Sweden)

    Andreia Macedo Gomes

    2017-07-01

    Full Text Available Recently, the Lean philosophy is gaining importance due to a competitive environment, which increases the need to reduce costs. Lean practices and tools have been applied to manufacturing, services, supply chain, startups and, the next frontier is healthcare. Most lean techniques can be easily adapted to health organizations. Therefore, this paper intends to summarize Lean practices and tools that are already being applied in health organizations. Among the numerous techniques and lean tools used, this research highlights the Simulation. Therefore, in order to understand the use of Simulation as a Lean Healthcare tool, this research aims to analyze, through the simulation technique, the operational dynamics of the service process of a fictitious hospital emergency unit. Initially a systematic review of the literature on the practices and tools of Lean Healthcare was carried out, in order to identify the main techniques practiced. The research highlighted Simulation as the sixth most cited tool in the literature. Subsequently, a simulation of a service model of an emergency unit was performed through the Arena software. As a main result, it can be highlighted that the attendants of the built model presented a degree of idleness, thus, they are able to atend a greater demand. As a last conclusion, it was verified that the emergency room is the process with longer service time and greater overload.

  6. Emergy Evaluation of Dwelling Operation in Five Housing Units of Montreal Island, Canada

    Directory of Open Access Journals (Sweden)

    Ricardo Enrique Vega-Azamar

    2017-04-01

    Full Text Available Sustainability of cities and the environmental implications of high resource utilization by the domestic sector are growing concerns related to urban regions. Well-informed urban planning decision-making is an essential tool to help in the task and, for that, an important point to consider is the influence of parameters like residential density and housing typology on the intensity of resource utilization. Emergy synthesis, a life-cycle energy analysis methodological approach that considers the interaction of natural and human-made flows, was used to evaluate the environmental support for dwelling operational stage in five typical present-day housing units on the island of Montreal. As expected, resource utilization, measured as total emergy used, was positively correlated to housing unit size both with respect to number of occupants and dwelling size. Results suggest that variables affecting notably the intensity of resource utilization are per household income and per dweller habitable space and, while a higher income increased per capita emergy in all cases, increasing space availability per resident did not result in a decrease of empower density after 50 m2/person. Future work should consider lower and higher densities and analyses at the scale of blocks, neighborhoods and urban planning zones.

  7. Limited field investigation report for the 100-HR-1 Operable Unit

    Energy Technology Data Exchange (ETDEWEB)

    1994-08-01

    This limited field investigation (LFI) report summarizes the data collection and analysis activities conducted during the 100-HR-1 Source Operable Unit LFI and the associated qualitative risk assessment (QRA) (WHC 1993a), and makes recommendations on the continued candidacy of high-priority sites for interim remedial measures (IRM). The results and recommendations presented in this report are generally independent of future land use scenarios. A LFI Report is required, in accordance with the HPPS, when waste sites are to be considered for IRMs. The LFI is an integral part of the remedial investigation/feasibility study (RI/FS) or Resource Conservation and Recovery Act (RCRA) facility investigation/corrective measures study (RFI/CMS) and process and functions as a focused RI or RFI for selection of IRMs. The purpose of the report is to identify those sites that are recommended to remain as candidates for IRMs, provide a preliminary summary of site characterization studies, refine the conceptual model as needed, identify contaminant- and location-specific applicable or relevant and appropriate requirements (ARA), and provide a qualitative assessment of the risks associated with the sites. This assessment includes consideration of whether contaminant concentrations pose an unacceptable risk that warrants action through IRMs. The 100-HR-1 unit encompasses approximately 100 acres adjacent to the Columbia River shoreline. It contains waste units associated with the original plant facilities constructed to support the H Reactor. The area also contains evaporation basins which received liquid process wastes and nonroutine deposits of chemical wastes from the 300 Area, where fuel elements for the N Reactor were produced.

  8. Can a stepwise steady flow computational fluid dynamics model reproduce unsteady particulate matter separation for common unit operations?

    Science.gov (United States)

    Pathapati, Subbu-Srikanth; Sansalone, John J

    2011-07-01

    Computational fluid dynamics (CFD) is emerging as a model for resolving the fate of particulate matter (PM) by unit operations subject to rainfall-runoff loadings. However, compared to steady flow CFD models, there are greater computational requirements for unsteady hydrodynamics and PM loading models. Therefore this study examines if integrating a stepwise steady flow CFD model can reproduce PM separation by common unit operations loaded by unsteady flow and PM loadings, thereby reducing computational effort. Utilizing monitored unit operation data from unsteady events as a metric, this study compares the two CFD modeling approaches for a hydrodynamic separator (HS), a primary clarifier (PC) tank, and a volumetric clarifying filtration system (VCF). Results indicate that while unsteady CFD models reproduce PM separation of each unit operation, stepwise steady CFD models result in significant deviation for HS and PC models as compared to monitored data; overestimating the physical size requirements of each unit required to reproduce monitored PM separation results. In contrast, the stepwise steady flow approach reproduces PM separation by the VCF, a combined gravitational sedimentation and media filtration unit operation that provides attenuation of turbulent energy and flow velocity.

  9. China's first home-made large ethylene unit put into operation in Daqing%China's first home-made large ethylene unit put into operation in Daqing

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    On October 5, the newly built 600kt/a ethylene unit at Daqing Petrochemical, a key part of the company's 1.2Mt/a ethylene expansion/upgrading project, turned out qualified products, indicating the successful industrialization of the packaged technology for China's first home-made large ethylene unit. This enables China to be independent from importing technologies for ethylene production which lasted for halfa century.

  10. Remedial investigation/feasibility study report for Lower Watts Bar Reservoir Operable Unit

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-03-01

    This document is the combined Remedial Investigation and Feasibility Study Report for the lower Watts Bar Reservoir (LWBR) Operable Unit (OU). The LWBR is located in Roane, Rhea, and Meigs counties, Tennessee, and consists of Watts Bar Reservoir downstream of the Clinch river. This area has received hazardous substances released over a period of 50 years from the US Department of Energy`s Oak Ridge Reservation (ORR), a National Priority List site established under the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA). As required by this law, the ORR and all off-site areas that have received contaminants, including LWBR, must be investigated to determine the risk to human health and the environment resulting from these releases, the need for any remedial action to reduce these risks, and the remedial actions that are most feasible for implementation in this OU. Contaminants from the ORR are primarily transported to the LWBR via the Clinch River. There is little data regarding the quantities of most contaminants potentially released from the ORR to the Clinch River, particularly for the early years of ORR operations. Estimates of the quantities released during this period are available for most radionuclides and some inorganic contaminants, indicating that releases 30 to 50 years ago were much higher than today. Since the early 1970s, the release of potential contaminants has been monitored for compliance with environmental law and reported in the annual environmental monitoring reports for the ORR.

  11. Some assembly required: constructing the elementary units of store-operated Ca2+ entry.

    Science.gov (United States)

    Wu, Minnie M; Luik, Riina M; Lewis, Richard S

    2007-08-01

    The means by which Ca(2+) store depletion evokes the opening of store-operated Ca(2+) channels (SOCs) in the plasma membrane of excitable and non-excitable cells has been a longstanding mystery. Indirect evidence has supported local interactions between the ER and SOCs as well as long-range interactions mediated through a diffusible activator. The recent molecular identification of the ER Ca(2+) sensor (STIM1) and a subunit of the CRAC channel (Orai1), a prototypic SOC, has now made it possible to visualize directly the sequence of events that links store depletion to CRAC channel opening. Following store depletion, STIM1 moves from locations throughout the ER to accumulate in ER subregions positioned within 10-25nm of the plasma membrane. Simultaneously, Orai1 gathers at discrete sites in the plasma membrane directly opposite STIM1, resulting in local CRAC channel activation. These new studies define the elementary units of store-operated Ca(2+) entry, and reveal an unprecedented mechanism for channel activation in which the stimulus brings a channel and its activator/sensor together for interaction across apposed membrane compartments. We discuss the implications of this choreographic mechanism with regard to Ca(2+) dynamics, specificity of Ca(2+) signaling, and the existence of a specialized ER subset dedicated to the control of the CRAC channel.

  12. Remedial design work plan for Lower East Fork Poplar Creek Operable Unit, Oak Ridge, Tennessee

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-10-01

    The Remedial Design Work Plan (RDWP) for Lower East Fork Poplar Creek (EFPC) Operable Unit (OU) in Oak Ridge, Tennessee. This remedial action fits into the overall Oak Ridge Reservation (ORR) cleanup strategy by addressing contaminated floodplain soil. The objective of this remedial action is to minimize the risk to human health and the environment from contaminated soil in the Lower EFPC floodplain pursuant to the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) and the Federal Facility Agreement (FFA) (1992). In accordance with the FFA, a remedial investigation (RI) (DOE 1994a) and a feasibility study (DOE 1994b) were conducted to assess contamination of the Lower EFPC and propose remediation alternatives. The remedial investigation determined that the principal contaminant is mercury, which originated from releases during Y-12 Plant operations, primarily between 1953 and 1963. The recommended alternative by the feasibility study was to excavate and dispose of floodplain soils contaminated with mercury above the remedial goal option. Following the remedial investigation/feasibility study, and also in accordance with the FFA, a proposed plan was prepared to more fully describe the proposed remedy.

  13. Operable Unit 1 remedial investigation report, Eielson Air Force Base, Alaska

    Energy Technology Data Exchange (ETDEWEB)

    Gilmore, T.J.; Fruland, R.M.; Liikala, T.L. [and others

    1994-06-01

    This remedial investigation report for operable Unit 1 (OU-1) at Eielson Air Force Base presents data, calculations, and conclusions as to the nature and extent of surface and subsurface contamination at the eight source areas that make up OU-1. The information is based on the 1993 field investigation result and previous investigations. This report is the first in a set of three for OU-1. The other reports are the baseline risk assessment and feasibility study. The information in these reports will lead to a Record of Decision that will guide and conclude the environmental restoration effort for OU-1 at Eielson Air Force Base. The primary contaminants of concern include fuels and fuel-related contaminants (diesel; benzene, toluene, ethylbenzene, and xylene; total petroleum hydrocarbon; polycyclic aromatic hydrocarbons), maintenance-related solvents and cleaners (volatile chlorinated hydrocarbons such as trichloroothylene), polychlorinated biphenyls, and dichlorodiphenyltrichloroethane (DDT). The origins of contaminants of concern include leaks from storage tanks, drums and piping, and spills. Ongoing operations and past sitewide practices also contribute to contaminants of concern at OU-1 source areas. These include spraying mixed oil and solvent wastes on unpaved roads and aerial spraying of DDT.

  14. Two-Dimensional Simulation of Mass Transfer in Unitized Regenerative Fuel Cells under Operation Mode Switching

    Directory of Open Access Journals (Sweden)

    Lulu Wang

    2016-01-01

    Full Text Available A two-dimensional, single-phase, isothermal, multicomponent, transient model is built to investigate the transport phenomena in unitized regenerative fuel cells (URFCs under the condition of switching from the fuel cell (FC mode to the water electrolysis (WE mode. The model is coupled with an electrochemical reaction. The proton exchange membrane (PEM is selected as the solid electrolyte of the URFC. The work is motivated by the need to elucidate the complex mass transfer and electrochemical process under operation mode switching in order to improve the performance of PEM URFC. A set of governing equations, including conservation of mass, momentum, species, and charge, are considered. These equations are solved by the finite element method. The simulation results indicate the distributions of hydrogen, oxygen, water mass fraction, and electrolyte potential response to the transient phenomena via saltation under operation mode switching. The hydrogen mass fraction gradients are smaller than the oxygen mass fraction gradients. The average mass fractions of the reactants (oxygen and hydrogen and product (water exhibit evident differences between each layer in the steady state of the FC mode. By contrast, the average mass fractions of the reactant (water and products (oxygen and hydrogen exhibit only slight differences between each layer in the steady state of the WE mode. Under either the FC mode or the WE mode, the duration of the transient state is only approximately 0.2 s.

  15. Large-Scale Pumping Test Recommendations for the 200-ZP-1 Operable Unit

    Energy Technology Data Exchange (ETDEWEB)

    Spane, Frank A.

    2010-09-08

    CH2M Hill Plateau Remediation Company (CHPRC) is currently assessing aquifer characterization needs to optimize pump-and-treat remedial strategies (e.g., extraction well pumping rates, pumping schedule/design) in the 200-ZP-1 operable unit (OU), and in particular for the immediate area of the 241 TX-TY Tank Farm. Specifically, CHPRC is focusing on hydrologic characterization opportunities that may be available for newly constructed and planned ZP-1 extraction wells. These new extraction wells will be used to further refine the 3-dimensional subsurface contaminant distribution within this area and will be used in concert with other existing pump-and-treat wells to remediate the existing carbon tetrachloride contaminant plume. Currently, 14 extraction wells are actively used in the Interim Record of Decision ZP-1 pump-and-treat system for the purpose of remediating the existing carbon tetrachloride contamination in groundwater within this general area. As many as 20 new extraction wells and 17 injection wells may be installed to support final pump-and-treat operations within the OU area. It should be noted that although the report specifically refers to the 200-ZP-1 OU, the large-scale test recommendations are also applicable to the adjacent 200-UP-1 OU area. This is because of the similar hydrogeologic conditions exhibited within these two adjoining OU locations.

  16. 100-OL-1 Operable Unit Pilot Study: XRF Evaluation of Select Pre-Hanford Orchards

    Energy Technology Data Exchange (ETDEWEB)

    Bunn, Amoret L.; Fritz, Brad G.; Pulsipher, Brent A.; Gorton, Alicia M.; Bisping, Lynn E.; Brandenberger, Jill M.; Pino, Christian; Martinez, Dominique M.; Rana, Komal; Wellman, Dawn M.

    2014-11-20

    Prior to the acquisition of land by the U.S. Department of War in February 1943 and the creation of the Hanford Site, the land along the Columbia River was home to over 1000 people. Farming and orchard operations by both homesteaders and commercial organizations were prevalent. Orchard activities and the associated application of lead arsenate pesticide ceased in 1943, when residents were moved from the Hanford Site at the beginning of the Manhattan Project. Today, the residues from historical application of lead arsenate pesticide persist in some locations on the Hanford Site. In 2012, the U.S. Department of Energy, U.S. Environmental Protection Agency, and Washington State Department of Ecology established the 100-OL-1 Operable Unit (OU) through the Hanford Federal Facility Agreement and Consent Order, known as the Tri-Party Agreement. The pre-Hanford orchard lands identified as the 100-OL-1 OU are located south of the Columbia River and east of the present-day Vernita Bridge, and extend southeast to the former Hanford townsite. The discontinuous orchard lands within 100-OL-1 OU are approximately 20 km2 (5000 ac). A pilot study was conducted to support the approval of the remedial investigation/feasibility study work plan to evaluate the 100-OL-1 OU. This pilot study evaluated the use of a field portable X-ray fluorescence (XRF) analyzer for evaluating lead and arsenic concentrations on the soil surface as an indicator of lead arsenate pesticide residues in the OU. The objectives of the pilot study included evaluating a field portable XRF analyzer as the analytical method for decision making, estimating the nature and extent of lead and arsenic in surface soils in four decision units, evaluating the results for the purpose of optimizing the sampling approach implemented in the remedial investigation, and collecting information to improve the cost estimate and planning the cultural resources review for sampling activities in the remedial investigation. Based on

  17. Impact of selection of cord blood units from the United States and swiss registries on the cost of banking operations.

    Science.gov (United States)

    Bart, Thomas; Boo, Michael; Balabanova, Snejana; Fischer, Yvonne; Nicoloso, Grazia; Foeken, Lydia; Oudshoorn, Machteld; Passweg, Jakob; Tichelli, Andre; Kindler, Vincent; Kurtzberg, Joanne; Price, Thomas; Regan, Donna; Shpall, Elizabeth J; Schwabe, Rudolf

    2013-02-01

    Over the last 2 decades, cord blood (CB) has become an important source of blood stem cells. Clinical experience has shown that CB is a viable source for blood stem cells in the field of unrelated hematopoietic blood stem cell transplantation. Studies of CB units (CBUs) stored and ordered from the US (National Marrow Donor Program (NMDP) and Swiss (Swiss Blood Stem Cells (SBSQ)) CB registries were conducted to assess whether these CBUs met the needs of transplantation patients, as evidenced by units being selected for transplantation. These data were compared to international banking and selection data (Bone Marrow Donors Worldwide (BMDW), World Marrow Donor Association (WMDA)). Further analysis was conducted on whether current CB banking practices were economically viable given the units being selected from the registries for transplant. It should be mentioned that our analysis focused on usage, deliberately omitting any information about clinical outcomes of CB transplantation. A disproportionate number of units with high total nucleated cell (TNC) counts are selected, compared to the distribution of units by TNC available. Therefore, the decision to use a low threshold for banking purposes cannot be supported by economic analysis and may limit the economic viability of future public CB banking. We suggest significantly raising the TNC level used to determine a bankable unit. A level of 125 × 10(7) TNCs, maybe even 150 × 10(7) TNCs, might be a viable banking threshold. This would improve the return on inventory investments while meeting transplantation needs based on current selection criteria.

  18. Monticello Mill Tailings Site, Operable Unit lll, Annual Groundwater Report, May 2015 Through April 2016

    Energy Technology Data Exchange (ETDEWEB)

    Nguyen, Jason [USDOE Office of Legacy Management (LM), Washington, DC (United States); Smith, Fred [Navarro Research and Engineering, Oak Ridge, TN (United States)

    2016-10-01

    This report provides the annual analysis of water quality restoration progress, cumulative through April 2016, for Operable Unit (OU) III, surface water and groundwater, of the U.S. Department of Energy (DOE) Office of Legacy Management (LM) Monticello Mill Tailings Site (MMTS). The MMTS is a Comprehensive Environmental Response, Compensation, and Liability Act National Priorities List site located in and near the city of Monticello, San Juan County, Utah. MMTS comprises the 110-acre site of a former uranium- and vanadium-ore-processing mill (mill site) and 1700 acres of surrounding private and municipal property. Milling operations generated 2.5 million cubic yards of waste (tailings) from 1942 to 1960. The tailings were impounded at four locations on the mill site. Inorganic constituents in the tailings drained from the impoundments to contaminate local surface water (Montezuma Creek) and groundwater in the underlying alluvial aquifer. Mill tailings dispersed by wind and water also contaminated properties surrounding and downstream of the mill site. Remedial actions to remove and isolate radiologically contaminated soil, sediment, and debris from the former mill site, Operable Unit I (OU I), and surrounding properties (OU II) were completed in 1999 with the encapsulation of the wastes in an engineered repository located on DOE property 1 mile south of the former mill site. This effectively removed the primary source of groundwater contamination; however, contamination of groundwater and surface water remains within OU III at levels that exceed water quality protection standards. Uranium is the primary contaminant of concern (COC). LM implemented monitored natural attenuation with institutional controls as the OU III remedy in 2004. Because groundwater restoration proceeded more slowly than expected and did not meet performance criteria established in the OU III Record of Decision (June 2004), LM implemented a contingency action in 2009 by an Explanation of

  19. Typhoid perforation: Post-operative Intensive Care Unit care and outcome

    Directory of Open Access Journals (Sweden)

    Mukaila Oyegbade Akinwale

    2016-01-01

    Full Text Available Background: Typhoid perforation ileitis is a serious complication of typhoid fever, a common and unfortunate health problem in a resource-poor country like Nigeria. Following bowel perforation, treatment is usually by simple closure or bowel resection and anastomosis after adequate aggressive fluid resuscitation and electrolyte correction. Postoperatively, some of these patients do require management in Intensive Care Unit (ICU on account of sepsis or septic shock and to improve survival. Patients and Methods: This is a prospective observational study in which 67 consecutive patients who had exploratory laparotomy for typhoid perforation between August 2009 and October 2012 in the main operating theatre of the University College Hospital, Ibadan, were studied. The attending anaesthetists had the freedom of choosing the appropriate anaesthetic drugs depending on the patients' clinical condition. The reason for admission into the ICU, the types of organ support required and outcomes were recorded. Results: Twenty-five patients (37.3% out of 67 required critical care. Reasons for admission among others included poor respiratory effort, hypotension, septic shock and delayed recovery from anaesthesia. Twenty-one patients (84% required mechanical ventilation with a mean duration of 2.14 days (range 1–5 days. Fourteen patients required ionotropic support and the length of ICU stay ranged from 1 to 15 days (mean 4.32 days. Nineteen patients (76% were successfully managed and discharged to the ward while 24% (6 patients mortality rate was recorded. Conclusion: This study showed high rate of post-operative ICU admission in patients with typhoid perforation with a high demand for critical care involving mechanical ventilation and ionotropic support. In centres that manage patients presenting with typhoid ileitis and perforation, post-operative critical care should be available.

  20. Typhoid perforation: Post-operative Intensive Care Unit care and outcome.

    Science.gov (United States)

    Akinwale, Mukaila Oyegbade; Sanusi, Arinola A; Adebayo, Oluwaseun K

    2016-01-01

    Typhoid perforation ileitis is a serious complication of typhoid fever, a common and unfortunate health problem in a resource-poor country like Nigeria. Following bowel perforation, treatment is usually by simple closure or bowel resection and anastomosis after adequate aggressive fluid resuscitation and electrolyte correction. Postoperatively, some of these patients do require management in Intensive Care Unit (ICU) on account of sepsis or septic shock and to improve survival. This is a prospective observational study in which 67 consecutive patients who had exploratory laparotomy for typhoid perforation between August 2009 and October 2012 in the main operating theatre of the University College Hospital, Ibadan, were studied. The attending anaesthetists had the freedom of choosing the appropriate anaesthetic drugs depending on the patients' clinical condition. The reason for admission into the ICU, the types of organ support required and outcomes were recorded. Twenty-five patients (37.3%) out of 67 required critical care. Reasons for admission among others included poor respiratory effort, hypotension, septic shock and delayed recovery from anaesthesia. Twenty-one patients (84%) required mechanical ventilation with a mean duration of 2.14 days (range 1-5 days). Fourteen patients required ionotropic support and the length of ICU stay ranged from 1 to 15 days (mean 4.32 days). Nineteen patients (76%) were successfully managed and discharged to the ward while 24% (6 patients) mortality rate was recorded. This study showed high rate of post-operative ICU admission in patients with typhoid perforation with a high demand for critical care involving mechanical ventilation and ionotropic support. In centres that manage patients presenting with typhoid ileitis and perforation, post-operative critical care should be available.

  1. Molten salt coal gasification process development unit. Phase 1. Volume 1. PDU operations. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Kohl, A.L.

    1980-05-01

    This report summarizes the results of a test program conducted on the Molten Salt Coal Gasification Process, which included the design, construction, and operation of a Process Development Unit. In this process, coal is gasified by contacting it with air in a turbulent pool of molten sodium carbonate. Sulfur and ash are retained in the melt, and a small stream is continuously removed from the gasifier for regeneration of sodium carbonate, removal of sulfur, and disposal of the ash. The process can handle a wide variety of feed materials, including highly caking coals, and produces a gas relatively free from tars and other impurities. The gasification step is carried out at approximately 1800/sup 0/F. The PDU was designed to process 1 ton per hour of coal at pressures up to 20 atm. It is a completely integrated facility including systems for feeding solids to the gasifier, regenerating sodium carbonate for reuse, and removing sulfur and ash in forms suitable for disposal. Five extended test runs were made. The observed product gas composition was quite close to that predicted on the basis of earlier small-scale tests and thermodynamic considerations. All plant systems were operated in an integrated manner during one of the runs. The principal problem encountered during the five test runs was maintaining a continuous flow of melt from the gasifier to the quench tank. Test data and discussions regarding plant equipment and process performance are presented. The program also included a commercial plant study which showed the process to be attractive for use in a combined-cycle, electric power plant. The report is presented in two volumes, Volume 1, PDU Operations, and Volume 2, Commercial Plant Study.

  2. Improving Inventory Management and Supply Chain of Diesel Fuel in Pertamina 5 Main Depots

    Directory of Open Access Journals (Sweden)

    Togar M Simatupang

    2012-01-01

    Full Text Available Planning Operation subdivision at PT Pertamina has to generate supply decisions includingmain depot to supply, supply point and transportation mode. However, the variability inplanning a supply schedule renders the process of determining a supply decision asineffective. The last assessment on uncertainties was done at 2006 and has not beenconsidered during decision making process. On the other hand, the result of this researchindicates that the uncertainty level is too high to be ignored and the poor informationexchange between the regional offices and the head office decreases the Planning Operation’sability to create plans that covers the company condition. This paper proposes an appropriatesafety stock to withstand the uncertainties and a supply scheduling process that also considersuncertainties by using Monte-Carlo Simulation with random numbers to simulate the events inthe upcoming period.Key words: inventory management, distribution planning, managing uncertainties, montecarlosimulation

  3. ERTS-1 DCS technical support provided by Wallops Station. [ground truth stations and DCP repair depot

    Science.gov (United States)

    Smith, R.

    1975-01-01

    Wallops Station accepted the tasks of providing ground truth to several ERTS investigators, operating a DCP repair depot, designing and building an airborne DCP Data Acquisition System, and providing aircraft underflight support for several other investigators. Additionally, the data bank is generally available for use by ERTS and other investigators that have a scientific interest in data pertaining to the Chesapeake Bay area. Working with DCS has provided a means of evaluating the system as a data collection device possibly applicable to ongoing Earth Resources Program activities in the Chesapeake Bay area as well as providing useful data and services to other ERTS investigators. The two areas of technical support provided by Wallops, ground truth stations and repair for DCPs, are briefly discussed.

  4. FEASIBILITY STUDY REPORT FOR THE 200-ZP-1 GROUNDWATER OPERABLE UNIT

    Energy Technology Data Exchange (ETDEWEB)

    BYRNES ME

    2008-07-18

    The Hanford Site, managed by the U.S. Department of Energy (DOE), encompasses approximately 1,517 km{sup 2} (586 mi{sup 2}) in the Columbia Basin of south-central Washington State. In 1989, the U.S. Environmental Protection Agency (EPA) placed the 100, 200, 300, and 1100 Areas of the Hanford Site on the 40 Code of Federal Regulations (CFR) 300, 'National Oil and Hazardous Substances Pollution Contingency Plan' National Contingency Plan [NCPD], Appendix B, 'National Priorities List' (NPL), pursuant to the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). The 200 Areas NPL sites consist of the 200 West and 200 East Areas (Figure 1-1). The 200 Areas contain waste management facilities, inactive irradiated fuel reprocessing facilities, and the 200 North Area (formerly used for interim storage and staging of irradiated fuel). Several waste sites in the 600 Area, located near the 200 Areas, also are included in the 200 Areas NPL site. The 200 Areas NPL site is in a region referred to as the 'Central Plateau' and consists of approximately 700 waste sites, excluding sites assigned to the tank farm waste management areas (WMAs). The 200-ZP-1 Groundwater Operable Unit (OU) consists of the groundwater located under the northern portion of the 200 West Area. Waste sources that contributed to the 200-ZP-1 OU included cribs and trenches that received liquid and/or solid waste in the past from the Z Plant and T Plant aggregate areas, WMA-T, WMA-TX/TY, and the State-Approved Land Disposal Site (SALDS). This feasibility study (FS) for the 200-ZP-1 Groundwater OU was prepared in accordance with the requirements of CERCLA decision documents. These decision documents are part of the Administrative Record for the selection of remedial actions for each waste site and present the selected remedial actions that are chosen in accordance with CERCLA, as amended by the Superfund Amendments and Reauthorization Act of 1986

  5. FEASIBILITY STUDY REPORT FOR THE 200-ZP-1 GROUNDWATER OPERABLE UNIT

    Energy Technology Data Exchange (ETDEWEB)

    BYRNES ME

    2008-07-18

    The Hanford Site, managed by the U.S. Department of Energy (DOE), encompasses approximately 1,517 km{sup 2} (586 mi{sup 2}) in the Columbia Basin of south-central Washington State. In 1989, the U.S. Environmental Protection Agency (EPA) placed the 100, 200, 300, and 1100 Areas of the Hanford Site on the 40 Code of Federal Regulations (CFR) 300, 'National Oil and Hazardous Substances Pollution Contingency Plan' National Contingency Plan [NCPD], Appendix B, 'National Priorities List' (NPL), pursuant to the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). The 200 Areas NPL sites consist of the 200 West and 200 East Areas (Figure 1-1). The 200 Areas contain waste management facilities, inactive irradiated fuel reprocessing facilities, and the 200 North Area (formerly used for interim storage and staging of irradiated fuel). Several waste sites in the 600 Area, located near the 200 Areas, also are included in the 200 Areas NPL site. The 200 Areas NPL site is in a region referred to as the 'Central Plateau' and consists of approximately 700 waste sites, excluding sites assigned to the tank farm waste management areas (WMAs). The 200-ZP-1 Groundwater Operable Unit (OU) consists of the groundwater located under the northern portion of the 200 West Area. Waste sources that contributed to the 200-ZP-1 OU included cribs and trenches that received liquid and/or solid waste in the past from the Z Plant and T Plant aggregate areas, WMA-T, WMA-TX/TY, and the State-Approved Land Disposal Site (SALDS). This feasibility study (FS) for the 200-ZP-1 Groundwater OU was prepared in accordance with the requirements of CERCLA decision documents. These decision documents are part of the Administrative Record for the selection of remedial actions for each waste site and present the selected remedial actions that are chosen in accordance with CERCLA, as amended by the Superfund Amendments and Reauthorization Act of 1986

  6. Day-Ahead Coordination of Vehicle-to-Grid Operation and Wind Power in Security Constraints Unit Commitment (SCUC

    Directory of Open Access Journals (Sweden)

    Mohammad Javad Abdollahi

    2015-08-01

    Full Text Available In this paper security constraints unit commitment (SCUC in the presence of wind power resources and electrical vehicles to grid is presented. SCUC operation prepare an optimal time table for generation unit commitment in order to maximize security, minimize operation cost and satisfy the constraints of networks and units in a period of time, as one of the most important research interest in power systems. Today, the relationship between power network and energy storage systems is interested for many researchers and network operators. Using Electrical Vehicles (PEVs and wind power for energy production is one of the newest proposed methods for replacing fossil fuels.One of the effective strategies for analyzing of the effects of Vehicle 2 Grid (V2G and wind power in optimal operation of generation is running of SCUC for power systems that are equipped with V2G and wind power resources. In this paper, game theory method is employed for deterministic solution of day-ahead unit commitment with considering security constraints in the simultaneous presence of V2G and wind power units. This problem for two scenarios of grid-controlled mode and consumer-controlled mode in three different days with light, medium and heavy load profiles is analyzed. Simulation results show the effectiveness of the presence of V2G and wind power for decreasing of generation cost and improving operation indices of power systems.

  7. Commissioning and quality assurances of the Intrabeam Intra-Operative radiotherapy unit

    Directory of Open Access Journals (Sweden)

    KR Muralidhar

    2014-12-01

    Full Text Available Purpose: The authors report comprehensive commissioning and quality assurance (QA procedures for Intrabeam, Intra-Operative radiotherapy (IORT unit. The Intrabeam system miniature X-ray source is a 50 kV and 40 µA unit. Methods: The authors’ tests include measurements of output, beam deflection, isotropy, kVp and mAs measurements, quality index, isodose, reproducibility, linearity, depth dose verification, and 3D dose distribution. IC ionization chamber and the UNIDOSE dosimeter were used for the output commissioning. Probe adjuster/ionization chamber holder (PAICH was used to check the mechanical straightness of the probe. For radiation tests, NACP parallel plate chamber, Standard Imaging electrometer, 30 × 30 × 30 cm3 IAEA water phantom, solid water slabs, EDR-2 Films with RIT software, and ionization based survey meters were used. Unfors Xi platinum edition kVp meter was used to measure the kVp and mAs. Results: In mechanical QA test, X-Beam position (-0.09 mm, Y-Beam position (0.01 mm, and radial position (0.11 mm errors were within the tolerance level. Isotropy test with PDA, survey meter, ion chamber, and film measurements also produced results within the specifications. Output measurements with PAICH and external chamber measurements were matched. Beam quality, linearity, and reproducibility values were ascertained at 50KV and 40 µA and found to be within limits. Isodose, 3D dose distribution, transverse, and horizontal profiles showed the good isotropy of the source. Conclusion: The authors’ methodology provides comprehensive commissioning and calibration procedures for the Intrabeam system.

  8. Very prolonged stay in the intensive care unit after cardiac operations: early results and late survival.

    Science.gov (United States)

    Silberman, Shuli; Bitran, Daniel; Fink, Daniel; Tauber, Rachel; Merin, Ofer

    2013-07-01

    Prolonged intensive care unit (ICU) stay is a surrogate for advanced morbidity or perioperative complications, and resource utilization may become an issue. It is our policy to continue full life support in the ICU, even for patients with a seemingly grim outlook. We examined the effect of duration of ICU stay on early outcomes and late survival. Between 1993 and 2011, 6,385 patients were admitted to the ICU after cardiac surgery. Patients were grouped according to length of stay in the ICU: group 1, 2 days or less (n = 4,631; 73%); group 2, 3 to 14 days (n = 1,423; 22%); group 3, more than 14 days (n = 331; 5%). Length of stay in ICU for group 3 patients was 38 ± 24 days (range, 15 to 160; median 31). Clinical profile and outcomes were compared between groups. Patients requiring prolonged ICU stay were older, underwent more complex surgery, had greater comorbidity, and a higher predicted operative mortality (p < 0.0001). They had a higher incidence of adverse events and increased mortality (p < 0.0001). Of the 331 group 3 patients, 60% were discharged: survival of these patients at 1, 3, and 5 years was 78%, 65%, and 52%, respectively. Operative mortality as well as late survival of discharged patients was proportional to duration of ICU stay. Current technology enables keeping sick patients alive for extended periods of time. Nearly two thirds of patients requiring prolonged ICU leave hospital, and of these, 50% attain 5-year survival. These data support offering full and continued support even for patients requiring very prolonged ICU stay. Copyright © 2013 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

  9. GROUDWATER REMEDIATION AT THE 100-HR-3 OPERABLE UNIT HANFORD SITE WASHINGTON USA - 11507

    Energy Technology Data Exchange (ETDEWEB)

    SMOOT JL; BIEBESHEIMER FH; ELUSKIE JA; SPILIOTOPOULOS A; TONKIN MJ; SIMPKIN T

    2011-01-12

    The 100-HR-3 Groundwater Operable Unit (OU) at the Hanford Site underlies three former plutonium production reactors and the associated infrastructure at the 100-D and 100-H Areas. The primary contaminant of concern at the site is hexavalent chromium; the secondary contaminants are strontium-90, technetium-99, tritium, uranium, and nitrate. The hexavalent chromium plume is the largest plume of its type in the state of Washington, covering an area of approximately 7 km{sup 2} (2.7 mi{sup 2}) with concentrations greater than 20 {micro}g/L. Concentrations range from 60,000 {micro}g/L near the former dichromate transfer station in the 100-D Area to large areas of 20 to 100 {micro}g/L across much of the plume area. Pump-and-treat operations began in 1997 and continued into 2010 at a limited scale of approximately 200 gal/min. Remediation of groundwater has been fairly successful in reaching remedial action objectives (RAOs) of 20 {micro}g/L over a limited region at the 100-H, but less effective at 100-D. In 2000, an in situ, permeable reactive barrier was installed downgradient of the hotspot in 100-D as a second remedy. The RAOs are still being exceeded over a large portion of the area. The CH2M HILL Plateau Remediation Company was awarded the remediation contract for groundwater in 2008 and initiated a remedial process optimization study consisting of modeling and technical studies intended to enhance the remediation. As a result of the study, 1,400 gal/min of expanded treatment capacity are being implemented. These new systems are designed to meet 2012 and 2020 target milestones for protection of the Columbia River and cleanup of the groundwater plumes.

  10. Operating room fire prevention: creating an electrosurgical unit fire safety device.

    Science.gov (United States)

    Culp, William C; Kimbrough, Bradly A; Luna, Sarah; Maguddayao, Aris J

    2014-08-01

    To reduce the incidence of surgical fires. Operating room fires represent a potentially life-threatening hazard and are triggered by the electrosurgical unit (ESU) pencil. Carbon dioxide is a fire suppressant and is a routinely used medical gas. We hypothesize that a shroud of protective carbon dioxide covering the tip of the ESU pencil displaces oxygen, thereby preventing fire ignition. Using 3-dimensional modeling techniques, a polymer sleeve was created and attached to an ESU pencil. This sleeve was connected to a carbon dioxide source and directed the gas through multiple precisely angled ports, generating a cone of fire-suppressive carbon dioxide surrounding the active pencil tip. This device was evaluated in a flammability test chamber containing 21%, 50%, and 100% oxygen with sustained ESU activation. The sleeve was tested with and without carbon dioxide (control) until a fuel was ignited or 30 seconds elapsed. Time to ignition was measured by high-speed videography. Fires were ignited with each control trial (15/15 trials). The control group median ± SD ignition time in 21% oxygen was 3.0 ± 2.4 seconds, in 50% oxygen was 0.1 ± 1.8 seconds, and in 100% oxygen was 0.03 ± 0.1 seconds. No fire was observed when the fire safety device was used in all concentrations of oxygen (0/15 trials; P fire ignition was 76% to 100%. A sleeve creating a cone of protective carbon dioxide gas enshrouding the sparks from an ESU pencil effectively prevents fire in a high-flammability model. Clinical application of this device may reduce the incidence of operating room fires.

  11. 5-year operation experience with the 1.8 K refrigeration units of the LHC cryogenic system

    CERN Document Server

    Ferlin, G; Claudet, S; Pezzetti, M

    2015-01-01

    Since 2009, the Large Hadron Collider (LHC) is in operation at CERN. The LHC superconducting magnets distributed over eight sectors of 3.3-km long are cooled at 1.9 K in pressurized superfluid helium. The nominal operating temperature of 1.9 K is produced by eight 1.8-K refrigeration units based on centrifugal cold compressors (3 or 4 stages depending to the vendor) combined with warm volumetric screw compressors with sub-atmospheric suction. After about 5 years of continuous operation, we will present the results concerning the availability for the final user of these refrigeration units and the impact of the design choice on the recovery time after a system trip. We will also present the individual results for each rotating machinery in terms of failure origin and of Mean Time between Failure (MTBF), as well as the consolidations and upgrades applied to these refrigeration units.

  12. Operation of the counter-rotating type pump-turbine unit installed in the power stabilizing system

    Science.gov (United States)

    Kanemoto, T.; Honda, H.; Kasahara, R.; Miyaji, T.

    2014-03-01

    This serial research intends to put a unique power stabilization system with a pumped storage into practical use. The pumped storage is equipped with a counter-rotating type pump-turbine unit whose operating mode can be shifted instantaneously in response to the fluctuation of power from renewable resources. This paper verifies that the system is reasonably effective to stabilize the fluctuating power. It is necessary to quickly increase the rotational speed when the operation is shifted from the turbine to the pumping modes, because the unit cannot pump-up water from a lower reservoir at a slow rotational speed while keeping gross/geodetic head constant. The maximum hydraulic efficiency at the turbine mode is close to the efficiency of the counter-rotating type hydroelectric unit designed exclusively for the turbine mode. The system is also provided for a pilot plant to be operated in the field.

  13. Disposal of chemical agents and munitions stored at Umatilla Depot Activity, Hermiston, Oregon

    Energy Technology Data Exchange (ETDEWEB)

    Zimmerman, G.P.; Hillsman, E.L.; Johnson, R.O.; Miller, R.L.; Patton, T.G.; Schoepfle, G.M.; Tolbert, V.R.; Feldman, D.L.; Hunsaker, D.B. Jr.; Kroodsma, R.L.; Morrissey, J.; Rickert, L.W.; Staub, W.P.; West, D.C.

    1993-02-01

    The Umatilla Depot Activity (UMDA) near Hermiston, Oregon, is one of eight US Army installations in the continental United States where lethal unitary chemical agents and munitions are stored, and where destruction of agents and munitions is proposed under the Chemical Stockpile Disposal Program (CSDP). The chemical agent inventory at UMDA consists of 11.6%, by weight, of the total US stockpile. The destruction of the stockpile is necessary to eliminate the risk to the public from continued storage and to dispose of obsolete and leaking munitions. In 1988 the US Army issued a Final Programmatic Environmental Impact Statement (FPEIS) for the CSDP that identified on-site disposal of agents and munitions as the environmentally preferred alternative (i.e., the alternative with the least potential to cause significant adverse impacts), using a method based on five measures of risk for potential human health and ecosystem/environmental effects; the effectiveness and adequacy of emergency preparedness capabilities also played a key role in the FPEIS selection methodology. In some instances, the FPEIS included generic data and assumptions that were developed to allow a consistent comparison of potential impacts among programmatic alternatives and did not include detailed conditions at each of the eight installations. The purpose of this Phase 1 report is to examine the proposed implementation of on-site disposal at UMDA in light of more recent and more detailed data than those included in the FPEIS. Specifically, this Phase 1 report is intended to either confirm or reject the validity of on-site disposal for the UMDA stockpile. Using the same computation methods as in the FPEIS, new population data were used to compute potential fatalities from hypothetical disposal accidents. Results indicate that onsite disposal is clearly preferable to either continued storage at UMDA or transportation of the UMDA stockpile to another depot for disposal.

  14. Gas production and transport in artificial sludge depots.

    Science.gov (United States)

    van Kessel, T; van Kesteren, W G M

    2002-01-01

    This paper presents a study to determine the impact of gas production in dredging sludge on the storage capacity of artificial sludge depots. Gas is produced as a result of the decomposition of organic material present in dredging spoil. This process, in which methane and carbon dioxide are formed, may lead to expansion of sludge layers, partly or even completely counterbalancing consolidation. The study shows that, even with a very conservative estimation of the rate of gas production, accumulation of gas occurs as convective and diffusive transport proceed very slowly. Nucleation of gas bubbles occurs already at a limited oversaturation of pore water. During their growth, bubbles push aside the surrounding grain matrix. Resulting stresses may initiate cracks around bubbles. If these cracks join, they may form channels stretching out to the depot surface and along which gas may escape. However, channels are only stable to a limited depth below which bubble accumulation may continue. The gas content at which sufficient cracks and channels are formed to balance the rate of gas production with the rate of outflow strongly depends on the constitutive properties of the dredging sludge considered. In sludge with a high shear strength (> 10 kPa), stable channels are created already at low deformations. However, a large expansion may occur in sludge with a low strength. The present study shows that accumulation of gas may continue until a bulk density less than that of water is attained. This is equivalent to a gas fraction of about 25-37%, depending on the initial water content of the sludge. Only then can gas escape as a result of instabilities in the sediment matrix. This should be well taken into account during the design and management of artificial depots.

  15. Data validation report for the 100-FR-3 Operable Unit, third round groundwater samples

    Energy Technology Data Exchange (ETDEWEB)

    Ayres, J.M.

    1994-03-31

    Westinghouse-Hanford has requested that a minimum of 20% of the total number of Sample Delivery Groups be validated for the 100-FR-3 operable Unit Third Round Groundwater sampling investigation. Therefore, the data from the chemical analysis of 51 samples from this sampling event and their related quality assurance samples were reviewed and validated to verify that reported sample results were of sufficient quality to support decisions regarding remedial actions performed at this site. The report is broken down into sections for each chemical analysis and radiochemical analysis type. Each section addresses the data package completeness, holding time adherence, instrument calibration and tuning acceptability, blank results, accuracy, precision, system performance, as well as the compound identification and quantitation. In addition, each section has an overall assessment and summary for the data packages reviewed for the particular chemical/radiochemical analyses. Detailed backup information is provided to the reader by SDG No. and sample number. For each data package, a matrix of chemical analyses per sample number is presented, as well as data qualification summaries.

  16. jMOTU and Taxonerator: turning DNA Barcode sequences into annotated operational taxonomic units.

    Directory of Open Access Journals (Sweden)

    Martin Jones

    Full Text Available BACKGROUND: DNA barcoding and other DNA sequence-based techniques for investigating and estimating biodiversity require explicit methods for associating individual sequences with taxa, as it is at the taxon level that biodiversity is assessed. For many projects, the bioinformatic analyses required pose problems for laboratories whose prime expertise is not in bioinformatics. User-friendly tools are required for both clustering sequences into molecular operational taxonomic units (MOTU and for associating these MOTU with known organismal taxonomies. RESULTS: Here we present jMOTU, a Java program for the analysis of DNA barcode datasets that uses an explicit, determinate algorithm to define MOTU. We demonstrate its usefulness for both individual specimen-based Sanger sequencing surveys and bulk-environment metagenetic surveys using long-read next-generation sequencing data. jMOTU is driven through a graphical user interface, and can analyse tens of thousands of sequences in a short time on a desktop computer. A companion program, Taxonerator, that adds traditional taxonomic annotation to MOTU, is also presented. Clustering and taxonomic annotation data are stored in a relational database, and are thus amenable to subsequent data mining and web presentation. CONCLUSIONS: jMOTU efficiently and robustly identifies the molecular taxa present in survey datasets, and Taxonerator decorates the MOTU with putative identifications. jMOTU and Taxonerator are freely available from http://www.nematodes.org/.

  17. An operational evaluation of the Community Oral Rehydration Units in Peru.

    Science.gov (United States)

    Benavides, B M; Jacoby, E R

    1994-12-01

    Since 1984, in Latin America donor agencies and national governments have extensively supported the implementation of the Community Oral Rehydration Units (CORUs) in an attempt to increase the access to oral rehydration therapy and improve the case management of diarrhoea at the community level. This study surveyed 40 CORUs in two regions of Peru to assess their operation, the number of patients with diarrhoea attended, and the knowledge of volunteers in charge. The results show that CORUs were mainly implemented close to existing health centres; the median of case load was 2.0 patients in the preceding month; and the volunteers' knowledge of case management was principally deficient in the diagnosis of hydration status, dietary management and in preventive measures. This lack of knowledge was replicated by professionals at the supervising health centres. Despite the fact that CORUs have been functioning for around four years, they exhibit numerous deficiencies which prevent them from fulfilling their objectives. A global review of the whole CORU strategy is called for.

  18. Qualitative research within trials: developing a standard operating procedure for a clinical trials unit

    Science.gov (United States)

    2013-01-01

    Background Qualitative research methods are increasingly used within clinical trials to address broader research questions than can be addressed by quantitative methods alone. These methods enable health professionals, service users, and other stakeholders to contribute their views and experiences to evaluation of healthcare treatments, interventions, or policies, and influence the design of trials. Qualitative data often contribute information that is better able to reform policy or influence design. Methods Health services researchers, including trialists, clinicians, and qualitative researchers, worked collaboratively to develop a comprehensive portfolio of standard operating procedures (SOPs) for the West Wales Organisation for Rigorous Trials in Health (WWORTH), a clinical trials unit (CTU) at Swansea University, which has recently achieved registration with the UK Clinical Research Collaboration (UKCRC). Although the UKCRC requires a total of 25 SOPs from registered CTUs, WWORTH chose to add an additional qualitative-methods SOP (QM-SOP). Results The qualitative methods SOP (QM-SOP) defines good practice in designing and implementing qualitative components of trials, while allowing flexibility of approach and method. Its basic principles are that: qualitative researchers should be contributors from the start of trials with qualitative potential; the qualitative component should have clear aims; and the main study publication should report on the qualitative component. Conclusions We recommend that CTUs consider developing a QM-SOP to enhance the conduct of quantitative trials by adding qualitative data and analysis. We judge that this improves the value of quantitative trials, and contributes to the future development of multi-method trials. PMID:23433341

  19. ALTERNATIVE REMEDIATION TECHNOLOGY STUDY FOR GROUNDWATER TREATMENT AT 200-PO-1 OPERABLE UNIT AT HANFORD SITE

    Energy Technology Data Exchange (ETDEWEB)

    DADO MA

    2008-07-31

    This study focuses on the remediation methods and technologies applicable for use at 200-PO-I Groundwater Operable Unit (OU) at the Hanford Site. The 200-PO-I Groundwater au requires groundwater remediation because of the existence of contaminants of potential concern (COPC). A screening was conducted on alternative technologies and methods of remediation to determine which show the most potential for remediation of groundwater contaminants. The possible technologies were screened to determine which would be suggested for further study and which were not applicable for groundwater remediation. COPCs determined by the Hanford Site groundwater monitoring were grouped into categories based on properties linking them by remediation methods applicable to each COPC group. The screening considered the following criteria. (1) Determine if the suggested method or technology can be used for the specific contaminants found in groundwater and if the technology can be applied at the 200-PO-I Groundwater au, based on physical characteristics such as geology and depth to groundwater. (2) Evaluate screened technologies based on testing and development stages, effectiveness, implementability, cost, and time. This report documents the results of an intern research project conducted by Mathew Dado for Central Plateau Remediation in the Soil and Groundwater Remediation Project. The study was conducted under the technical supervision of Gloria Cummins and management supervision of Theresa Bergman and Becky Austin.

  20. First Operational Experience with the LHC Beam Dump Trigger Synchronisation Unit

    CERN Document Server

    Antoine, A; Magnin, N; Juteau, P; Voumard, N

    2011-01-01

    Two LHC Beam Dumping Systems (LBDS) remove the counter-rotating beams safely from the collider during setting up of the accelerator, at the end of a physics run and in case of emergencies. Dump requests can come from 3 different sources: the machine protection system in emergency cases, the machine timing system for scheduled dumps or the LBDS itself in case of internal failures. These dump requests are synchronized with the 3 μs beam abort gap in a fail-safe redundant Trigger Synchronization Unit (TSU) based on a Digital Phase Locked Loop (DPLL), locked onto the LHC beam revolution frequency with a maximum phase error of 40 ns. The synchronized trigger pulses coming out of the TSU are then distributed to the high voltage generators of the beam dump kickers through a redundant fault-tolerant trigger distribution system. This paper describes the operational experience gained with the TSU since its commissioning with beam in 2009, and highlights the improvements, which have been implemented f...

  1. Depot effect of bioactive components in experimental membrane filtrations

    Science.gov (United States)

    Mitev, D.; Peshev, D.; Peev, G.; Peeva, L.

    2017-01-01

    Depot effects were found to be accompanying phenomena of membrane separation processes. Accumulation of target species in the membrane matrix during feasibility tests can hamper proper conclusions or compromise the filtration results. Therefore, we investigated the effects of delayed membrane release of chlorogenic acid and caffeine, considered as key compounds of interest in spent coffee products’ recovery treatment. Permeate fluxes and key components release were studied in course of 24 hours via nanofiltration of pure solvent, both immediately after the mock solution filtration and after idle stay. Conclusions are drawn and recommendations advised for proper analysis of experimental data on membrane screening.

  2. Invasive cervical cancer and depot-medroxyprogesterone acetate

    OpenAIRE

    1985-01-01

    Preliminary results of a study of the possible relationship of depot-medroxy-progesterone acetate (DMPA) to invasive cervical cancer are presented. The findings are based on data from three participating centres in Thailand and one in Mexico. A relative risk for cervical cancer of 1.2 was observed in women who had ever used DMPA; this was not statistically significant. No consistent increase in risk with duration of use was observed, although a relative risk of 2 was found in women who had us...

  3. Comparison of heuristic approaches for the multiple depot vehicle scheduling problem

    NARCIS (Netherlands)

    A.S. Pepin; G. Desaulniers (Guy); A. Hertz (Alain); D. Huisman (Dennis)

    2006-01-01

    textabstractGiven a set of timetabled tasks, the multi-depot vehicle scheduling problem is a well-known problem that consists of determining least-cost schedules for vehicles assigned to several depots such that each task is accomplished exactly once by a vehicle. In this paper, we propose to compar

  4. Treating allergic rhinitis with depot-steroid injections increase risk of osteoporosis and diabetes

    DEFF Research Database (Denmark)

    Aasbjerg, Kristian; Torp-Pedersen, Christian; Vaag, Allan

    2013-01-01

    In Denmark, 23% of the adult population have allergic rhinitis. We have previously demonstrated that a majority of hay fever patients are treated with depot-steroid injections in violation of the guidelines. It has been hypothesised that 1-2 annual depot-steroid injections are not harmful...

  5. Pharmacokinetics in Elderly Women of Benzyl Alcohol From an Oil Depot

    NARCIS (Netherlands)

    Kalicharan, Raween; El Amrani, Mohsin; Schot, Peter; Vromans, Herman|info:eu-repo/dai/nl/073088803

    2016-01-01

    Pharmaceutical oil depots are meant to release active substances at a sustained rate. Most of these depots contain benzyl alcohol (BOH) to facilitate the production and administration. Because BOH changes the solubility of components in both the body fluid and the oil formulation, it is relevant to

  6. Micro-cogeneration units based on Stirling engine for heating and their real operation

    Science.gov (United States)

    Čierny, Jaroslav; Patsch, Marek

    2014-08-01

    This article was deal with micro-cogeneration units based on Stirling engine. We watched problematic of real working Stirling engine. The article also contain hookup of unit constructed at University of Zilina.

  7. Disposal of chemical agents and munitions stored at Anniston Army Depot, Anniston, Alabama

    Energy Technology Data Exchange (ETDEWEB)

    Hunsaker, D.B. Jr.; Zimmerman, G.P.; Hillsman, E.L.; Miller, R.L.; Schoepfle, G.M.; Johnson, R.O.; Tolbert, V.R.; Kroodsma, R.L.; Rickert, L.W.; Rogers, G.O.; Staub, W.P.

    1990-09-01

    The purpose of this Phase I report is to examined the proposed implementation of on-site disposal at Anniston Army Depot (ANAD) in light of more detailed and more recent data than those included in the Final Programmatic Environmental Impact Statement (EPEIS). Two principal issues are addressed: (1) whether or not the new data would result in identification of on-site disposal at ANAD as the environmentally preferred alternative (using the same selection method and data analysis tools as in the FPEIS), and (2) whether or not the new data indicate the presence of significant environmental resources that could be affected by on-site disposal at ANAD. In addition, a status report is presented on the maturity of the disposal technology (and now it could affect on-site disposal at ANAD). Inclusion of these more recent data into the FPEIS decision method resulted in confirmation of on-site disposal for ANAD. No unique resources with the potential to prevent or delay implementation of on-site disposal at ANAD have been identified. A review of the technology status identified four principal technology developments that have occurred since publication of the FPEIS and should be of value in the implementation of on-site disposal at ANAD: the disposal of nonlethal agent at Pine Bluff Arsenal, located near Pine Bluff, Arkansas; construction and testing of facilities for disposal of stored lethal agent at Johnston Atoll, located about 1300 km (800 miles) southwest of Hawaii in the Pacific Ocean; lethal agent disposal tests at the chemical agent pilot plant operations at Tooele Army Depot, located near Salt Lake City, Utah; and equipment advances. 18 references, 13 figs., 10 tabs.

  8. Policies for Positioning Empty Containers in an Inland Multi-depot System

    DEFF Research Database (Denmark)

    Dang, Vinh Quang; Nielsen, Izabela Ewa; Yun, Won-Young

    2011-01-01

    This research focuses on the problem of positioning empty containers in a port area with multiple depots. Three options are considered to prepare the required extent of positioning: positioning from other overseas ports, inland positioning between depots, and leasing. The policies for empty......-container management are as follows: a coordinated (s, S) inventory policy for overseas positioning, (ri, Ri) policy at each depot for inland positioning; and a simple leasing policy with zero lead-time. For inland positioning policy, four different methods are proposed to reposition empty containers between depots....... Customer demands and returning containers in depots and lead-time for positioning from overseas are considered as uncertain factors. The objective is to obtain the optimal policy in order to minimize the expected total cost including inventory holding, overseas positioning, inland positioning and leasing...

  9. From neutrophils to macrophages: differences in regional adipose tissue depots.

    Science.gov (United States)

    Dam, V; Sikder, T; Santosa, S

    2016-01-01

    Currently, we do not fully understand the underlying mechanisms of how regional adiposity promotes metabolic dysregulation. As adipose tissue expands, there is an increase in chronic systemic low-grade inflammation due to greater infiltration of immune cells and production of cytokines. This chronic inflammation is thought to play a major role in the development of metabolic complications and disease such as insulin resistance and diabetes. We know that different adipose tissue depots contribute differently to the risk of metabolic disease. People who have an upper body fat distribution around the abdomen are at greater risk of disease than those who tend to store fat in their lower body around the hips and thighs. Thus, it is conceivable that adipose tissue depots contribute differently to the inflammatory milieu as a result of varied infiltration of immune cell types. In this review, we describe the role and function of major resident immune cells in the development of adipose tissue inflammation and discuss their regional differences in the context of metabolic disease risk. We find that although initial studies have found regional differences, a more comprehensive understanding of how immune cells interrupt adipose tissue homeostasis is needed.

  10. Artificial immune algorithm for multi-depot vehicle scheduling problems

    Science.gov (United States)

    Wu, Zhongyi; Wang, Donggen; Xia, Linyuan; Chen, Xiaoling

    2008-10-01

    In the fast-developing logistics and supply chain management fields, one of the key problems in the decision support system is that how to arrange, for a lot of customers and suppliers, the supplier-to-customer assignment and produce a detailed supply schedule under a set of constraints. Solutions to the multi-depot vehicle scheduling problems (MDVRP) help in solving this problem in case of transportation applications. The objective of the MDVSP is to minimize the total distance covered by all vehicles, which can be considered as delivery costs or time consumption. The MDVSP is one of nondeterministic polynomial-time hard (NP-hard) problem which cannot be solved to optimality within polynomial bounded computational time. Many different approaches have been developed to tackle MDVSP, such as exact algorithm (EA), one-stage approach (OSA), two-phase heuristic method (TPHM), tabu search algorithm (TSA), genetic algorithm (GA) and hierarchical multiplex structure (HIMS). Most of the methods mentioned above are time consuming and have high risk to result in local optimum. In this paper, a new search algorithm is proposed to solve MDVSP based on Artificial Immune Systems (AIS), which are inspirited by vertebrate immune systems. The proposed AIS algorithm is tested with 30 customers and 6 vehicles located in 3 depots. Experimental results show that the artificial immune system algorithm is an effective and efficient method for solving MDVSP problems.

  11. 300-FF-1 Operable Unit physical separation of soils pilot plant study

    Energy Technology Data Exchange (ETDEWEB)

    Freeman-Pollard, J.R.

    1994-01-15

    Alternative Remedial Technologies, Inc. (ART) was selected in a competitive selection process to conduct a pilot study for the physical separation of soils in the North Process Pond of the 300 Area at the Hanford Site. In January 1994, ART mobilized its 15 tons-per-hour pilot plant to the site. The plant was initially staged in a commercial area to allow for pretest inspections and minor modifications. The plant was specifically designed for use as a physical separations unit and consisted of a feed hopper, wet screens, hydrocyclones, as well as settling and dewatering equipment. The plant was supported in the field with prescreening equipment, mobile generators, air compressors, and water storage tanks. The plant was moved into the surface contamination area on March 24, 1994. The testing was conducted during the period March 23, 1994 through April 13, 1994. Two soil types were treated during the testing: a natural soil contaminated with low levels of uranium, cesium, cobalt, and heavy metals, and a natural soil contaminated with a uranium carbonate material that was visually recognizable by the presence of a green sludge material in the soil matrix. The ``green`` material contained significantly higher levels of the same contaminants. Both source materials were treated by the plant in a manner that fed the material, produced clean gravel and sand fractions, and concentrated the contaminants in a sludge cake. Process water was recycled during the operations. The testing was extremely successful in that for both source waste streams, it was demonstrated that volume reductions of greater than 90% could be achieved while also meeting the test performance criteria. The volume reduction for the natural soils averaged a 93.8%, while the ``green`` soils showed a 91.4% volume reduction.

  12. Methods to model particulate matter clarification of unit operations subject to unsteady loadings.

    Science.gov (United States)

    Spelman, David; Sansalone, John J

    2017-05-15

    Stormwater, and also wastewater unit operations (UOs) to a much lower extent, are subject to unsteady hydrodynamic and particulate matter (PM) fluxes. Simulating fully transient clarification of hetero-disperse PM requires much greater computational expense compared to steady simulations. An alternative to fully unsteady methods are stepwise steady (SS) methods which use stepwise steady flow transport and fate to approximate unsteady PM clarification of a UO during transient hydraulic loadings such as rainfall-runoff. The rationale is reduced computational effort for computational fluid dynamics (CFD) compared to simulating continuous unsteadiness of such events. An implicit solution stepwise steady (IS(3)) method is one approach which builds upon previous SS methods. The IS(3) method computes steady flows that are representative of unsteady PM transport throughout an unsteady loading. This method departs from some previous SS methods that assume PM fate can be simulated with an instantaneous clarifier (basin) influent flowrate coupled with a PM input. In this study, various SS methods were tested for basins of varying size and residence time to examine PM fate. Differences between SS methods were a function of turnover fraction indicating the role of unsteady flowrates on PM transport for larger basins of longer residence times. The breakpoint turnover fraction was between two and three. The IS(3) method best approximated unsteady behavior of larger basins. These methods identified limitations when utilizing standard event-based loading analysis for larger basins. For basins with a turnover fraction less than two, the majority of effluent PM did not originate from the event-based flow; originating from previous event loadings or existing storage. Inter- and multiple event processes and interactions, that are dependent on this inflow turnover fraction, are not accounted for by single event-based inflow models. Results suggest the use of long-term continuous

  13. Phase 1 and 2 feasibility study report for the 300-FF-1 Operable Unit

    Energy Technology Data Exchange (ETDEWEB)

    1993-11-01

    The 300-FF-1 Operable Unit (OU) feasibility study (FS) presented in this document completes the FS process only through the first two study phases: Phase I, Remedial Alternatives Development, and Phase II, Remedial Alternatives Screening in accordance with CERCIA guidance for performing Remedial Investigations and Feasibility Studies (RI/FS) (EPA 1988a). This Phase I/II study provides a generalized view of workable remedial technologies as applied to the site contamination problems as a whole. Phase III, Detailed Analysis of Alternatives, will be performed at a later date to further evaluate screened alternatives based on the nine criteria in the CERCLA RI/FS guidance. The purpose of this Phase I/II FS is to develop and screen a range of alternatives for remediation of contamination present in the vadose zone of the 300-FF-1 OU. The scope of work for this Phase I/II FS includes five primary tasks: 1. Review existing documents and their associated data from relevant investigations and studies; 2. Establish remedial action objectives (RAO) and general response actions (GRA); 3. Identify applicable or relevant and appropriate requirements (ARARS) pertinent to all general response actions (including waste disposal); 4. Develop remedial alternatives (Phase I) applicable to the 300-FF-1 OU including identification and screening of technologies and process options, and assembly of remedial alternatives from representative technology types; 5. Screen alternatives (Phase II) developed in Phase I for implementability, effectiveness, and cost to identify those alternatives which warrant advancement to the detailed analysis phase (Phase III) of the FS.

  14. Fiscal Year 2009 Annual Report for Operable Unit 3-14, Tank Farm Soil and INTEC Groundwater

    Energy Technology Data Exchange (ETDEWEB)

    Forsythe, Howard S.

    2010-04-10

    This annual report summarizes maintenance, monitoring, and inspection activities performed to implement the selected remedy for Waste Area Group 3, Operable Unit 3-14, Tank Farm soil and groundwater at the Idaho Nuclear Technology and Engineering Center located within the Idaho National Laboratory Site. Results from monitoring perched water and groundwater at the Idaho Nuclear Technology and Engineering Center are also presented.

  15. Teaching Mass Transfer and Filtration Using Crossflow Reverse Osmosis and Nanofiltration: An Experiment for the Undergraduate Unit Operations Lab

    Science.gov (United States)

    Anastasio, Daniel; McCutcheon, Jeffrey

    2012-01-01

    A crossflow reverse osmosis (RO) system was built for a senior-level chemical engineering unit operations laboratory course. Intended to teach students mass transfer fundamentals related to membrane separations, students tested several commercial desalination membranes, measuring water flux and salt rejections at various pressures, flow rates, and…

  16. Teaching Mass Transfer and Filtration Using Crossflow Reverse Osmosis and Nanofiltration: An Experiment for the Undergraduate Unit Operations Lab

    Science.gov (United States)

    Anastasio, Daniel; McCutcheon, Jeffrey

    2012-01-01

    A crossflow reverse osmosis (RO) system was built for a senior-level chemical engineering unit operations laboratory course. Intended to teach students mass transfer fundamentals related to membrane separations, students tested several commercial desalination membranes, measuring water flux and salt rejections at various pressures, flow rates, and…

  17. Groundwater geochemical and selected volatile organic compound data, Operable Unit 1, Naval Undersea Warfare Center, Division Keyport, Washington, July 2015

    Science.gov (United States)

    Huffman, Raegan L.

    2016-05-18

    Previous investigations indicate that concentrations of chlorinated volatile organic compounds (CVOCs) are substantial in groundwater beneath the 9-acre former landfill at Operable Unit 1, Naval Undersea Warfare Center, Division Keyport, Washington. The U.S. Geological Survey has continued to monitor groundwater geochemistry to ensure that conditions remain favorable for contaminant biodegradation as specified in the Record of Decision for the site.

  18. Prevalence of Giardia duodenalis assemblages in weaned cattle on cow-calf operations in the United States

    Science.gov (United States)

    To determine the prevalence of Giardia duodenalis in weaned beef calves in cow-calf operations in the United States, fecal specimens were collected from 819 calves (6 to18 months of age) in 20 states from 49 locations. After cleaning and concentration procedures to maximize the potential recovery of...

  19. Pyrosequencing as a tool for the detection of Phytophthora species: error rate and risk of false Molecular Operational Taxonomic Units

    NARCIS (Netherlands)

    Vettraino, A.M.; Bonants, P.J.M.; Tomassini, A.; Bruni, N.; Vannini, A.

    2012-01-01

    Aims: To evaluate the accuracy of pyrosequencing for the description of Phytophthora communities in terms of taxa identification and risk of assignment for false Molecular Operational Taxonomic Units (MOTUs). Methods and Results: Pyrosequencing of Internal Transcribed Spacer 1 (ITS1) amplicons was u

  20. 78 FR 14361 - U.S. Steel Tubular Products, Inc., Mckeesport Tubular Operations Division, Subsidiary of United...

    Science.gov (United States)

    2013-03-05

    ... Employment and Training Administration U.S. Steel Tubular Products, Inc., Mckeesport Tubular Operations Division, Subsidiary of United States Steel Corporation, Mckeesport, PA; Notice of Initiation of...) filed on December 20, 2012 on behalf of workers of U.S. Steel Tubular Products, McKeesport...

  1. Remedial Design/Remedial Action Work Plan for Operable Units 6-05 and 10-04, Phase III

    Energy Technology Data Exchange (ETDEWEB)

    R. P. Wells

    2006-09-19

    The remedial design/remedial action for Operable Unit 6-05 (Waste Area Group 6) and Operable Unit 10-04 (Waste Area Group 10) - collectively called Operable Unit 10-04 has been divided into four phases. Phase I consists of developing and implementing institutional controls at Operable Unit 10-04 sites and developing and implementing Idaho National Laboratory-wide plans for both institutional controls and ecological monitoring. Phase II will remediate sites contaminated with trinitrotoluene and Royal Demolition Explosive. Phase III will remediate lead contamination at a gun range, and Phase IV will remediate hazards from unexploded ordnance. This Phase III remedial Design/Remedial Action Work Plan addresses the remediation of lead-contaminated soils found at the Security Training Facility (STF)-02 Gun Range located at the Idaho National Laboratory. Remediation of the STF-02 Gun Range will include excavating contaminated soils; physically separating copper and lead for recycling; returning separated soils below the remediation goal to the site; stabilizing contaminated soils, as required, and disposing of the separated soils that exceed the remediation goal; encapsulating and disposing of creosote-contaminated railroad ties and power poles; removing and disposing of the wooden building and asphalt pads found at the STF-02 Gun Range; sampling and analyzing soil to determine the excavation requirements; and when the remediation goals have been met, backfilling and contouring excavated areas and revegetating the affected area.

  2. Prevalence of roll-over protective structure (ROPS)-equipped tractors on Hispanic-operated farms in the United States.

    Science.gov (United States)

    Myers, John R

    2010-04-01

    Roll-over protective structures (ROPS) are known to prevent tractor overturn deaths, but not enough tractors are equipped with them in the United States to reduce the rate of these deaths to levels seen in several European countries. Recent literature has defined the use of ROPS on US farms in general, but little is known about ROPS use on Hispanic farm operations. Data from a national survey for the calendar year 2003 were used to assess the prevalence of ROPS use on Hispanic-operated farms. Farm characteristics previously identified to be associated with low ROPS prevalence rates on other farming operations were examined for these Hispanic farming operations. The overall ROPS prevalence rate on Hispanic farms was 52.2%. Adjusted odds ratios of potential risk factors found that the region where the farm was located and the acreage of the farm appeared to be the most significant indicators of the prevalence of ROPS on Hispanic farms. In addition, the age of the farm operator, the farm status as a full- or part-time operation, and the type of farm operation were also important factors. These findings were similar to those seen for racial minority farms and the general farming population. These results can be used to target ROPS promotion programs for Hispanic farmers across the United States.

  3. Operative and technological management of super-large united power grids: lessons of major world's blackouts

    Science.gov (United States)

    Brinkis, K.; Kreslins, V.; Mutule, A.

    2014-02-01

    Power system (PS) blackouts still persist worldwide, evidencing that the existing protective structures need to be improved. The discussed requirements and criteria to be met for joint synchronous operation of large and super-large united PSs should be based on close co-ordination of operative and technological management of all PSs involved in order to ensure secure and stable electricity supply and minimise or avoid the threat of a total PS blackout. The authors analyse the July 2012 India blackout - the largest power outage in history, which affected over 620 million people, i.e. half of India's population and spread across its 22 states. The analysis is of a general character, being applicable also to similar blackouts that have occurred in Europe and worldwide since 2003. The authors summarise and develop the main principles and methods of operative and technological management aimed at preventing total blackouts in large and super-large PSs. Neskatoties uz sasniegumiem elektroenerģētikas jomā un energosistēmu nepārtrauktu modernizāciju, pasaulē regulāri notiek sabrukumu avārijas. Rakstā apskatīti lielu un superlielu energosistēmu apvienību savstarpējas sinhronas darbības nodrošinājuma prasības un kritēriji, kas pamatojas uz operatīvās un tehnoloģiskās vadības ciešu koordināciju starp energosistēmām. Savstarpējas sinhronas darbības nodrošinājuma prasībām un kritērijiem ir izšķiroša nozīme, lai panāktu elektroapgādes drošumu un stabilitāti katrā energosistēmā, kas darbojas apvienotas energosistēmas sastāvā. Šo prasību un kritēriju ievērošana sekmē totālo avāriju izcelšanās iespēju samazināšanu un to novēršanu. Indijas 2012.gada totālo avāriju un citu analogo avāriju Eiropā un Amerikā analīze un izvērtējums laika posmā no 2003.gada, deva iespēju apkopot un izstrādāt lielu un superlielu energosistēmu operatīvās un tehnoloģiskās vadības principus un metodoloģiju, lai novērstu vai

  4. Global Strategy Implementation at the Business Unit Level: Operational Capabilities and Administrative Mechanisms

    OpenAIRE

    Kendall Roth; David M Schweiger; Allen J Morrison

    1991-01-01

    The study examines the impact of internationally strategy on organizational design and the influence of the organizational design on effectiveness at the business unit level. The empirical findings are based on survey responses from eighty-two business units competing in global industries. The findings are supportive of the contingency notion which suggests that business unit effectiveness is a function of the fit between the international strategy and the organizational design.© 1991 JIBS. J...

  5. Global Strategy Implementation at the Business Unit Level: Operational Capabilities and Administrative Mechanisms

    OpenAIRE

    Kendall Roth; David M Schweiger; Allen J Morrison

    1991-01-01

    The study examines the impact of internationally strategy on organizational design and the influence of the organizational design on effectiveness at the business unit level. The empirical findings are based on survey responses from eighty-two business units competing in global industries. The findings are supportive of the contingency notion which suggests that business unit effectiveness is a function of the fit between the international strategy and the organizational design.© 1991 JIBS. J...

  6. Assessment of the feasibility of an improvement programme enabling operation of units 3 and 4 of Kozloduy nuclear power plant

    Energy Technology Data Exchange (ETDEWEB)

    Amri, A.; Aronov, J.; Bonino, F.; Cortes, P.; Gorbatchev, A.; Kanev, K.; Mattei, J.M.; Milhem, J.L.; Rollinger, F.; Sabotinov, L.; Samier, L. [Commissariat a l' Energie Atomique, 92 - Fontenay-aux-Roses (FR). Inst. de Protection et de Securete Nucleaire (IPSN)

    2001-07-01

    Since ten years, different western assessments have been made of the safety of VVER 440/230 units, including those of the KOZLODUY Nuclear Power Plant located in Bulgaria. Concerning the latter, reference can be made to the work of an European Consortium (GRS/Germany, IPSN/France, AEA/England, AVN/ Belgium), in 1992 and 1993, during examination of restart conditions for Units 1 and 2. The objective of these assessments was the improvement of the overall level of safety with a view to maintain these units in service with satisfactory safety level for a limited period. The work identified their main deficiencies. At the present time, all the modifications decided upon for Units 1 and 2 of the KOZLODUY Nuclear Power Plant in 1992 and 1993 have been adopted and implemented for Units 3 and 4. In 1999, considering that these units would probably not be definitively shutdown before about ten years, IPSN decided to perform an internal assessment of the feasibility of an improvement programme enabling continued operation of units 3 and 4 of KOZLODUY Nuclear Power Plant during this delay. (orig.)

  7. Record of Decision for Tank Farm Soil and INTEC Groundwater, Operable Unit 3-14

    Energy Technology Data Exchange (ETDEWEB)

    L. S. Cahn

    2007-05-16

    This decision document presents the selected remedy for Operable Unit (OU) 3-14 tank farm soil and groundwater at the Idaho Nuclear Technology and Engineering Center (INTEC), which is located on the Idaho National Laboratory (INL) Site. The tank farm was initially evaluated in the OU 3-13 Record of Decision (ROD), and it was determined that additional information was needed to make a final decision. Additional information has been obtained on the nature and extent of contamination in the tank farm and on the impact to groundwater. The selected remedy was chosen in accordance with the Comprehensive Environmental Response, Liability and Compensation Act of 1980 (CERCLA) (42 USC 9601 et seq.), as amended by the Superfund Amendments and Reauthorization Act of 1986 (Public Law 99-499) and the National Oil and Hazardous Substances Pollution Contingency Plan (40 CFR 300). The selected remedy is intended to be the final action for tank farm soil and groundwater at INTEC. The response action selected in this ROD is necessary to protect the public health, welfare, or the environment from actual or threatened releases of hazardous substances into the environment. Such a release or threat of release may present an imminent and substantial endangerment to public health, welfare, or the environment. The remedial actions selected in this ROD are designed to reduce the potential threats to human health and the environment to acceptable levels. In addition, DOE-ID, EPA, and DEQ (the Agencies) have determined that no action is necessary under CERCLA to protect public health, welfare, or the environment at 16 sites located outside the tank farm boundary. The purposes of the selected remedy are to (1) contain contaminated soil as the radionuclides decay in place, (2) isolate current and future workers and biological receptors from contact with contaminated soil, and (3) restore the portion of Snake River Plain Aquifer contaminated by INTEC releases to Idaho Ground Water Quality

  8. BIOTIC INTEGRITY OF STREAMS IN THE SAVANNAH RIVER SITE INTEGRATOR OPERABLE UNITS, 1996 TO 2003

    Energy Technology Data Exchange (ETDEWEB)

    Paller, M; Susan Dyer, S

    2004-11-08

    The Savannah River Site (SRS) has been divided into six Integrator Operable Units (IOUs) that correspond to the watersheds of the five major streams on the SRS (Upper Three Runs, Fourmile Branch, Pen Branch, Steel Creek, and Lower Three Runs) and the portions of the Savannah River and Savannah River Swamp associated with the SRS. The streams are the primary integrators within each IOU because they potentially receive, through surface or subsurface drainage, soluble contaminants from all waste sites within their watersheds. If these contaminants reach biologically significant levels, they would be expected to effect the numbers, types, and health of stream organisms. In this study, biological sampling was conducted within each IOU as a measure of the cumulative ecological effects of the waste sites within the IOUs. The use of information from biological sampling to assess environmental quality is often termed bioassessment. The IOU bioassessment program included 38 sites in SRS streams and nine sites in the Savannah River. Sampling was conducted in 1996 to 1998, 2000, and 2003. Four bioassessment methods were used to evaluate ecological conditions in the IOU streams: the Index of Biotic Integrity, the Fish Health Assessment Index, measurement of fish tissue contaminant levels, and two benthic macroinvertebrate indices. The Index of Biotic Integrity (IBI) is an EPA supported method based on comparison of ecologically important and sensitive fish assemblage variables between potentially disturbed and reference (i.e., undisturbed) sites. It is designed to assess the ability of a stream to support a self-sustaining biological community and ecological processes typical of undisturbed, natural conditions. Since many types of contaminants can bioaccumulate, fish tissue contaminant data were used to determine the types of chemicals fish were exposed to and their relative magnitudes among IOUs. The Fish Health Assessment Index (HAI) is an EPA supported method for assessing

  9. 活性炭油气回收装置运行分析%Analysis of Oil Gas Recovery Unit Operation

    Institute of Scientific and Technical Information of China (English)

    韩栋樑; 丁波

    2015-01-01

    油品在储存和运输过程中,经常会有一部分液态轻烃组分汽化而进入大气中,不仅会造成一定的油品数量的损失和质量的下降,还会带来安全隐患和环境污染,因此对产生的油气进行回收显得十分重要,通过对浙江地区多座油库现役油气回收装置的分析,给出了影响其回收效果的主要因素,提出了一些措施,以提高装置的回收效率和安全性。%There is usually a part of the light hydrocarbon liquid components vaporize into the atmosphere in the process of oil storage and transportation, which will not only cause some loss of oil quantity and quality decline, but also cause a security risk and environmental pollution. Therefore, recycling oil vapor is very important. Through the analysis of the oil gas recovery unit in the depot showed the main factors affecting the recovery effect, and some measures to improve the recovery efficiency and safety of the device were put forward.

  10. Performance-Based Technology Selection Filter application report for Teledyne Wah Chang Albany Operable Unit Number One

    Energy Technology Data Exchange (ETDEWEB)

    Richardson, J.G.; Morrison, J.L.; Morneau, R.A.; O' Brien, M.C.; Rudin, M.J.

    1992-05-01

    This report summarizes the application of the Performance-Based Technology Selection Filter (PBTSF) developed for the Idaho National Laboratory's Buried Waste Integrated Demonstration Program as applied to remediation activities conducted at the Teledyne Wah Chang Albany (TWCA) Superfund Site, Operable Unit One. The remedial action at the TWCA Operable Unit One consisted of solidification, excavation, transportation, and monocell disposal of the contents of two sludge ponds contaminated with various inorganic and organic compounds. Inorganic compounds included low levels of uranium and radium isotopes, as well zirconium, hafnium, chromium, mercury, and nickel. Organic compounds included methylene chloride, 1,1,1-trichloroethane, 1,1-dichloroethane, tetrachloroethane, and hexachlorobenzene. Remediation began in June 1991, and was completed in November 1991. The TWCA Operable Unit One configuration option consisted of 15 functional subelements. Data were gathered on these subelements and end-to-end system operation to calculate numerical values for 28 system performance measures. These were then used to calculate a system performance score. An assessment was made of the availability and definitional clarity of these performance measures, applicability of PBTSF utility functions, and rollup methodology. The PBTSF scoring function worked well, with few problems noted in data gathering, utility function normalization, and scoring calculation. The application of this process to an actual in situ treatment and excavation technical process option clarified the specific terms and bounds of the performance score functions, and identified one problem associated with the definition of system boundary.

  11. Intrinsic differences in adipocyte precursor cells from different white fat depots

    DEFF Research Database (Denmark)

    Macotela, Yazmín; Emanuelli, Brice; Mori, Marcelo A;

    2012-01-01

    Obesity and body fat distribution are important risk factors for the development of type 2 diabetes and metabolic syndrome. Evidence has accumulated that this risk is related to intrinsic differences in behavior of adipocytes in different fat depots. In the current study, we demonstrate...... is higher in obesity-prone C57BL/6 mice than obesity-resistant 129 mice, and the number in both depots is increased by up to 270% by exposure of mice to high-fat diet. Thus, APCs from visceral and subcutaneous depots are dynamic populations, which have intrinsic differences in gene expression...

  12. The Linehaul-Feeder Vehicle Routing Problem with Virtual Depots and Time Windows

    Directory of Open Access Journals (Sweden)

    Huey-Kuo Chen

    2011-01-01

    Full Text Available This paper addresses the linehaul-feeder vehicle routing problem with virtual depots and time windows (LFVRPTW. Small and large vehicles deliver services to customers within time constraints; small vehicles en route may reload commodities from either the physical depot or from the larger vehicle at a virtual depot before continuing onward. A two-stage solution heuristic involving Tabu search is proposed to solve this problem. The test results show that the LFVRPTW performs better than the vehicle routing problem with time windows in terms of both objective value and the number of small vehicles dispatched.

  13. United States Department of Energy Nevada Operations Office Environmental Compliance Handbook. Third edition

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    The Environment, Safety & Health Division (ESHD) of the Nevada Operations Office has prepared this Environmental Compliance Handbook for all users of the Nevada Test Site (NTS) and other US Department of Energy, Nevada Operations Office (DOE/NV) facilities. The Handbook gives an overview of the important environmental laws and regulations that apply to the activities conducted by the Nevada Operations Office and other users of DOE/NV facilities in Nevada.

  14. Liquid phase methanol LaPorte Process Development Unit: Modification, operation, and support studies

    Energy Technology Data Exchange (ETDEWEB)

    1991-02-28

    The LPMEOH process was conceived and patented by Chem Systems Inc. in 1975. Initial research and studies on the process focused on two distinct modes of operation. The first was a liquid fluidized mode with relatively large catalyst pellets suspended in a fluidizing liquid, and the second was an entrained (slurry) mode with fine catalyst particles slurried in an inert liquid. The development of both operating modes progressed in parallel from bench scale reactors, through an intermediate scale lab PDU, and then to the LaPorte PDU in 1984. The slurry mode of operation was ultimately chosen as the operating mode of choice due to its superior performance.

  15. Invasive cervical cancer and depot-medroxyprogesterone acetate

    Science.gov (United States)

    1985-01-01

    Preliminary results of a study of the possible relationship of depot-medroxy-progesterone acetate (DMPA) to invasive cervical cancer are presented. The findings are based on data from three participating centres in Thailand and one in Mexico. A relative risk for cervical cancer of 1.2 was observed in women who had ever used DMPA; this was not statistically significant. No consistent increase in risk with duration of use was observed, although a relative risk of 2 was found in women who had used DMPA for more than 5 years. This observed increase in risk was confined to women who were aged under 46 years or who had first been exposed to DMPA before 30 years of age. These findings are based on small numbers of subjects, and may not represent a causal relationship. PMID:2931205

  16. Sex dimorphism and depot differences in adipose tissue function.

    Science.gov (United States)

    White, Ursula A; Tchoukalova, Yourka D

    2014-03-01

    Obesity, characterized by excessive adiposity, is a risk factor for many metabolic pathologies, such as type 2 diabetes mellitus (T2DM). Numerous studies have shown that adipose tissue distribution may be a greater predictor of metabolic health. Upper-body fat (visceral and subcutaneous abdominal) is commonly associated with the unfavorable complications of obesity, while lower-body fat (gluteal-femoral) may be protective. Current research investigations are focused on analyzing the metabolic properties of adipose tissue, in order to better understand the mechanisms that regulate fat distribution in both men and women. This review will highlight the adipose tissue depot- and sex-dependent differences in white adipose tissue function, including adipogenesis, adipose tissue developmental patterning, the storage and release of fatty acids, and secretory function. This article is part of a Special Issue entitled: Modulation of Adipose Tissue in Health and Disease.

  17. Analysis of United States Marine Corps operations in support of humanitarian assistance and disaster relief

    OpenAIRE

    Gastrock, Jared R.; Iturriaga, Juan J.

    2013-01-01

    Approved for public release; distribution is unlimited. In order to improve the effectiveness of the United States Marine Corps (USMC) response to future international humanitarian assistance/disaster relief (HA/DR) missions, an analysis of the demands created by such disasters as well as the capabilities of the USMC is necessary. This research focuses on the primary response organization within the USMC, the Marine expeditionary unit (MEU),and those resources available to the MEU to condu...

  18. Modern technologies for rendering information support to cogeneration steam turbine units in their design and operation stages

    Science.gov (United States)

    Brezgin, V. I.; Brodov, Yu. M.; Chubarov, A. A.; Brezgin, D. V.

    2013-08-01

    Application of modern information technologies in different stages of the lifecycle of cogeneration turbines is considered as one of possible ways for improving their competitiveness. Specific features relating to rendering information support for steam turbine units during the periods of their design and operation, which are the main stages of their life cycle, are presented. Three-dimension modeling, adaptive, and parametric design technologies are applied in the equipment design stages. Information support technologies developed by the authors are applied during the operation stage. Information is integrated by using a product lifecycle management (PLM) system.

  19. Construction and operation of the flue gas desulphurization plant at Altbach/Deizisau power station, unit no. 5. Experience from commissioning and initial operating period

    Energy Technology Data Exchange (ETDEWEB)

    Maier, R.; Necker, P.; Strauss, J.; Hemming, H.; Landgraf, E.

    1987-04-01

    Since take-over the flue gas desulphurization plant has easily maintained the required level of desulphurisation. Caking-on and incrustation are substantially avoided. By redesigning the gypsum drying process an easily storable gypsum which can be used both in the gypsum and cement industry is produced. According to experience gained to date it is expected that the flue gas desulphurisation plant will not impair the availability of the power plant unit taking into account statutory regulations. In overall terms the plant has satisfactorily fulfilled the expectations of the operator.

  20. Inverse spectral results for Schrödinger operators on the unit interval with partial information given on the potentials

    Science.gov (United States)

    Amour, L.; Faupin, J.; Raoux, T.

    2009-03-01

    We pursue the analysis of the Schrödinger operator on the unit interval in inverse spectral theory initiated in the work of Amour and Raoux ["Inverse spectral results for Schrödinger operators on the unit interval with potentials in Lp spaces," Inverse Probl. 23, 2367 (2007)]. While the potentials in the work of Amour and Raoux belong to L1 with their difference in Lp (1≤p<∞), we consider here potentials in Wk,1 spaces having their difference in Wk,p, where 1≤p≤+∞, k ɛ{0,1,2}. It is proved that two potentials in Wk,1([0,1]) being equal on [a,1] are also equal on [0,1] if their difference belongs to Wk,p([0,a]) and if the number of their common eigenvalues is sufficiently high. Naturally, this number decreases as the parameter a decreases and as the parameters k and p increase.

  1. Baseline risk assessment for the quarry residuals operable unit of the Weldon Spring Site, Weldon Spring, Missouri

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-02-01

    The U.S. Department of Energy (DOE) is conducting cleanup activities at the Weldon Spring site, located in St. Charles County, Missouri, about 48 km (30 mi) west of St. Louis. Cleanup of the site consists of several integrated components. The quarry residuals operable unit (QROU), consisting of the Weldon Spring quarry and its surrounding area, is one of four operable units being evaluated. In accordance with requirements of the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), as amended, DOE is conducting a remedial investigation/feasibility study (RI/FS) to determine the proper response to address various contaminated media that constitute the QROU. Specifically, the operable unit consists of the following areas and media: the residual material remaining at the Weldon Spring quarry after removal of the pond water and the bulk waste; groundwater underlying the quarry and surrounding area; and other media located in the surrounding vicinity of the quarry, including surface water and sediment at Femme Osage Slough, Little Femme Osage Creek, and Femme Osage Creek. An initial evaluation of conditions at the quarry area identified remaining data requirements needed to support the conceptual site exposure and hydrogeological models. These data requirements are discussed in the RI/FS work plan issued in January 1994. Soil contamination located at a property adjacent to the quarry, referred to as Vicinity Property 9 (VP9), was originally part of the scope of the QROU, as discussed in the work plan. However, a decision was subsequently made to remediate this vicinity property as part of cleanup activities for the chemical plant operable unit, as provided for in the Record of Decision (ROD). Remediation of VP9 was completed in early 1996. Hence, this baseline risk assessment (BRA) does not address VP9.

  2. KC-46A Formal Training Unit (FTU) and First Main Operating Base (MOB 1) Beddown EIS. Volume 1

    Science.gov (United States)

    2014-03-01

    support a1rcraft operations and pHot and personnel training • ht UMI O~f’t EIS, the USAF ldet~titJ.s AltUS AF8 as the PTI~ fened A#etnAtfv• for liH! FTV...Frequency, commonly perceived as pitch, is the number of times per second the sound causes air molecules to oscillate . Frequency is measured in units of

  3. Mass and number size distributions of emitted particulates at five important operation units in a hazardous industrial waste incineration plant.

    Science.gov (United States)

    Lin, Chi-Chi; Huang, Hsiao-Lin; Hsiao, Wen-Yuan

    2016-01-01

    Past studies indicated particulates generated by waste incineration contain various hazardous compounds. The aerosol characteristics are very important for particulate hazard control and workers' protection. This study explores the detailed characteristics of emitted particulates from each important operation unit in a rotary kiln-based hazardous industrial waste incineration plant. A dust size analyzer (Grimm 1.109) and a scanning mobility particle sizer (SMPS) were used to measure the aerosol mass concentration, mass size distribution, and number size distribution at five operation units (S1-S5) during periods of normal operation, furnace shutdown, and annual maintenance. The place with the highest measured PM10 concentration was located at the area of fly ash discharge from air pollution control equipment (S5) during the period of normal operation. Fine particles (PM2.5) constituted the majority of the emitted particles from the incineration plant. The mass size distributions (elucidated) made it clear that the size of aerosols caused by the increased particulate mass, resulting from work activities, were mostly greater than 1.5 μm. Whereas the number size distributions showed that the major diameters of particulates that caused the increase of particulate number concentrations, from work activities, were distributed in the sub micrometer range. The process of discharging fly ash from air pollution control equipment can significantly increase the emission of nanoparticles. The mass concentrations and size distributions of emitted particulates were different at each operation unit. This information is valuable for managers to take appropriate strategy to reduce the particulate emission and associated worker exposure.

  4. Cost-Optimal Operation of Energy Storage Units: Benefits of a Problem-Specific Approach

    CERN Document Server

    Siemer, Lars; Kleinhans, David

    2015-01-01

    The integration of large shares of electricity produced by non-dispatchable Renewable Energy Sources (RES) leads to an increasingly volatile energy generation side, with temporary local overproduction. The application of energy storage units has the potential to use this excess electricity from RES efficiently and to prevent curtailment. The objective of this work is to calculate cost-optimal charging strategies for energy storage units used as buffers. For this purpose, a new mathematical optimization method is presented that is applicable to general storage-related problems. Due to a tremendous gain in efficiency of this method compared with standard solvers and proven optimality, calculations of complex problems as well as a high-resolution sensitivity analysis of multiple system combinations are feasible within a very short time. As an example technology, Power-to-Heat converters used in combination with thermal storage units are investigated in detail and optimal system configurations, including storage ...

  5. Replenishment policies for Empty Containers in an Inland Multi-depot System

    DEFF Research Database (Denmark)

    Dang, Quang-Vinh; Nielsen, Izabela Ewa; Yun, W. Y.

    2013-01-01

    This research focuses on the problem of positioning empty containers in a port area with multiple depots. Three options are considered: positioning from other overseas ports, inland positioning between depots and leasing. The policies for empty-container management are as follows: a coordinated (s......, S) inventory policy for overseas positioning, a (ri, Ri) policy at each depot for inland positioning, and a simple leasing policy with zero lead-time and infinite capacity. For the inland positioning policy, four different methods are proposed to reposition empty containers between depots....... The objective is to obtain the optimal policy in order to minimize the expected total cost consisting of: inventory holding, overseas positioning, inland positioning and leasing costs. A simulation-based genetic algorithm is developed to find near-optimal policies. Numerical examples are given to demonstrate...

  6. 75 FR 3943 - Southern Nuclear Operating Company, Inc.; Vogtle Electric Generating Plant, Units 1 and 2...

    Science.gov (United States)

    2010-01-25

    .... NPF-68 and NPF-81, issued to Southern Nuclear Operating Company, Inc. (SNC, the licensee), for... contained in 10 CFR 73.55 by the March 31, 2010, implementation deadline. SNC has proposed an alternate...

  7. Superfund record of decision (EPA Region 5): Feed Materials Production Center, (USDOE), Operable Unit 1, Fernald, Hamilton and Butler Counties, OH, March 1, 1995. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-02-01

    The decision document presents the selected remedial action for Operable Unit 1 of the FEMP site in Hamilton and Butler Counties, Ohio. Operable Unit 1 consists of Waste Pits 1 through 6, the Burn Pit, the Clearwell, and associated environmental media (excluding groundwater).

  8. COMPACT DIFFERENCES OF COMPOSITION OPERATORS ON HOLOMORPHIC FUNCTION SPACES IN THE UNIT BALL

    Institute of Scientific and Technical Information of China (English)

    Jiang Liangying; Ouyang Caiheng

    2011-01-01

    We find a lower bound for the essential norm of the difference of two composition operators acting on H2(BN) or A28(BN) (s > -1).This result plays an important role in proving a necessary and sufficient condition for the difference of linear fractional composition operators to be compact,which answers a question posed by MacCluer and Weir in 2005.

  9. A Variable Neighborhood Search-Based Heuristic for the Multi-Depot Vehicle Routing Problem

    Directory of Open Access Journals (Sweden)

    Arif Imran

    2013-01-01

    Full Text Available The multi-depot vehicle routing problem (MDVRP is addressed using an adaptation of the variable neighborhood search (VNS. The proposed VNS algorithm besides using several neighborhoods and a number of local searches has a number of additional features. These include a scheme for identifying borderline customers, a diversivication procedure and a mechanism that aggregates and disaggregates routes between depots. The proposed algorithm is tested on the data instances from the literature and produces competitive results.

  10. Differential screening identifies transcripts with depot-dependent expression in white adipose tissues

    Directory of Open Access Journals (Sweden)

    Zhou Shengli

    2008-08-01

    Full Text Available Abstract Background The co-morbidities of obesity are tied to location of excess fat in the intra-abdominal as compared to subcutaneous white adipose tissue (WAT depot. Genes distinctly expressed in WAT depots may impart depot-dependent physiological functions. To identify such genes, we prepared subtractive cDNA libraries from murine subcutaneous (SC or intra-abdominal epididymal (EP white adipocytes. Results Differential screening and qPCR validation identified 7 transcripts with 2.5-fold or greater enrichment in EP vs. SC adipocytes. Boc, a component of the hedgehog signaling pathway demonstrated highest enrichment (~12-fold in EP adipocytes. We also identified a dramatic enrichment in SC adipocytes vs. EP adipocytes and in SC WAT vs. EP WAT for transcript(s for the major urinary proteins (Mups, small secreted proteins with pheromone functions that are members of the lipocalin family. Expression of Boc and Mup transcript was further assessed in murine tissues, adipogenesis models, and obesity. qPCR analysis reveals that EP WAT is a major site of expression of Boc transcript. Furthermore, Boc transcript expression decreased in obese EP WAT with a concomitant upregulation of Boc transcript in the obese SC WAT depot. Assessment of the Boc binding partner Cdon in adipose tissue and cell fractions thereof, revealed transcript expression similar to Boc; suggestive of a role for the Boc-Cdon axis in WAT depot function. Mup transcripts were predominantly expressed in liver and in the SC and RP WAT depots and increased several thousand-fold during differentiation of primary murine preadipocytes to adipocytes. Mup transcripts were also markedly reduced in SC WAT and liver of ob/ob genetically obese mice compared to wild type. Conclusion Further assessment of WAT depot-enriched transcripts may uncover distinctions in WAT depot gene expression that illuminate the physiological impact of regional adiposity.

  11. Use of Special Operations Forces in United Nations Missions: a Method to Resolve Complexity

    Science.gov (United States)

    2015-05-21

    mission. The aggressive approach the unit adopted for clearing the city of Goma and the surrounding areas from rebels required accurate intelligence...the city of Goma . The ability of soldiers from the Special Forces Company to access remote areas, coordinate aviation attacks, and conduct surgical

  12. Closing the Door Behind You: How the United States Army Conducts Logistical Withdrawals after Lengthy Operations

    Science.gov (United States)

    2013-05-23

    complicating this process was a similar use of identified excess to ship to other countries units, such as Thailand. The Keystone architecture was...2006, Sunni extremists attacked a mosque in Samarra, one of the holiest sites in Shiite Islam. This action initiated a spiraling level of violence

  13. A Delphi Study of Additive Manufacturing Applicability for United States Air Force Civil Engineer Contingency Operations

    Science.gov (United States)

    2015-03-26

    research examines the possibilities for the integration of additive manufacturing (AM) machines in United States Air Force civil engineer (CE...popularity in many applications. One of these developing applications is the use of additive manufacturing machines for the production of supplies in...capability is the inclusion of additive manufacturing (AM) machines in certain CE UTCs. Additive manufacturing is the process of constructing

  14. Catalyzed steam gasification of biomass. Phase 3: Biomass Process Development Unit (PDU) construction and initial operation

    Science.gov (United States)

    Healey, J. J.; Hooverman, R. H.

    1981-12-01

    The design and construction of the process development unit (PDU) are described in detail, examining each system and component in order. Siting, the chip handling system, the reactor feed system, the reactor, the screw conveyor, the ash dump system, the PDU support equipment, control and information management, and shakedown runs are described.

  15. An Investigation Into the Feasibility of Merging Three Technical Processing Operations Into One Central Unit.

    Science.gov (United States)

    Burns, Robert W., Jr.

    Three contiguous schools in the upper midwest--a teacher's training college and a private four-year college in one state, and a land-grant university in another--were studied to see if their libraries could merge one of their major divisions--technical services--into a single administrative unit. Potential benefits from such a merger were felt to…

  16. The Implications of Network-Centric Warfare for United States and Multinational Military Operations

    Science.gov (United States)

    2007-11-02

    31. Rear Admiral D. Mayo, Bandwidth Baseline Assesment Memo, <http://copernicus.hq.navy.mil/crwg98/briefs/brownbag_bam.pdf>, p. 22. 14... smoke signals or drums, or carefully selected commercial technology? The United States experience in Somalia and the Russian experience in

  17. Factors That Influence Human Behavior And Negatively Affect Energy Consumption In USMC Ground Units During Operations

    Science.gov (United States)

    2016-09-01

    Boston: Prentice Hall Bulanow, Peter, Paul Tabler, and Shawn Charchan. 2011. Expeditionary Energy Assessment: Environmental Control Unit Alternatives...U.S. ARMY Rapid Equipping Force. Kotter, John P., and Leonard Schlesinger. 2008. “Choosing Strategies for Change.” Harvard Business Review 86.7

  18. Economic Viability of Pumped-Storage Power Plants Equipped with Ternary Units and Considering Hydraulic Short-Circuit Operation

    Science.gov (United States)

    Chazarra, Manuel; Pérez-Díaz, Juan I.; García-González, Javier

    2017-04-01

    This paper analyses the economic viability of pumped-storage hydropower plants equipped with ternary units and considering hydraulic short-circuit operation. The analysed plant is assumed to participate in the day-ahead energy market and in the secondary regulation service of the Spanish power system. A deterministic day-ahead energy and reserve scheduling model is used to estimate the maximum theoretical income of the plant assuming perfect information of the next day prices and the residual demand curves of the secondary regulation reserve market. Results show that the pay-back periods with and without the hydraulic short-circuit operation are significantly lower than their expected lifetime and that the pay-back periods can be reduced with the inclusion of the hydraulic short-circuit operation.

  19. LeanERP® Mobile Platform Solution for Planning, Visualization and Execution of Business Operations in MSME Unit

    Directory of Open Access Journals (Sweden)

    Dr . Jayakumar Karuppusamy

    2013-02-01

    Full Text Available The paper presents the design and development of a solution framework for a LeanERP® interactive application for use with mobile handheld devices, which enables profile based activity logging, planning and execution of tasks, information sharing, collaboration and decision support aligned with the enterprise operations. The design leverages intelligence with the use of cognitive approaches, classifier systems and a data driven approach for adaptive profiling and configuration of software behavior. The solution is well suited for MSME units as the architecture is designed on the basis of a SOA for rapid adaptation and deployment for a given cluster and presents an engaging role centric GUI with multiple widgets and tabs for dynamic visualization of information relating to enterprise operations with trails and traceability of process flows, events, activities, analysis and cost estimates. The solution integrates mechanisms, data structures, algorithms and associated computational models that enable presentation of performance characteristics, predictions and appropriate options for decisions relating to various operations

  20. A study on scattered dose in operation room by C-arm unit

    Energy Technology Data Exchange (ETDEWEB)

    An, Sung Min; Oh, Jung Hwan; Kim, Sung Chul [Gachon Gil College, Incheon (Korea, Republic of)

    2000-04-15

    This paper studied a C-arm's exposure condition and measured scatter rays by thickness and distance. This study reached the following conclusion. Approximately exposure dose for a patient using fluoroscopy is as follows: Mostly, an operating room was not shielding by lead and operator put on only apron without thyroid and facial part protection. 0.5 mmPb equivalent's apron shielded about 99% of scattered rays at 60 cm from x-ray tube. Scattered rays are depended on distance and thickness so operators are should be careful when using fluoroscopy by C-arm and if possible use high frequency equipment that has a large output.

  1. Operational characteristics of tractors driven by children on farms in the United States and Canada.

    Science.gov (United States)

    Marlenga, B; Pickett, W; Berg, R L; Murphy, D

    2004-01-01

    Farm tractors are an important source of traumatic injury for children on farms. There is, however, no documentation about the age and size of tractors that children are operating and little information about the frequency with which rollover protective structures (ROPS) are used. This study described tractors that children on farms in the U.S. and Canada were operating by age, horsepower, and the presence of ROPS, according to the age and gender of the farm children involved. As a sub-analysis of data compiled during a randomized controlled trial, a descriptive analysis was completed on work exposure data collected by telephone interview. Of the 1,113 children involved in the trial, 522 (47%) were reported to perform at least one job that involved the operation of a farm tractor, and 408 (36.7%) were operating tractors of at least 20 horsepower. The majority of these children were male. There was a wide range of ages and sizes of tractors operated. However, the majority of tractors were between 20 and 70 horsepower and manufactured after 1970. Nearly one-half of the tractors were equipped with ROPS, and these tended to be newer and larger tractors. This analysis provides new data about the broad range of tractors driven by farm children in the U.S. and Canada. The findings point to a need to re-examine the reliance on a single voluntary standard to mitigate the hazard of tractor rollovers and the need for an enhanced safety policy requiring all tractors operated by children be equipped with ROPS.

  2. Oxy-fired boiler unit and method of operating the same

    Energy Technology Data Exchange (ETDEWEB)

    Lou, Xinsheng; Zhang, Jundong; Joshi, Abhinaya; McCombe, James A.; Levasseur, Armand A.

    2016-12-06

    An oxy-combustion boiler unit is disclosed which includes a furnace for combusting fuel and for emitting flue gas resulting from combustion. The furnace has first, second and third combustion zones, and an air separation unit for separating oxygen gas from air and providing a first portion of the separated oxygen to a first oxidant flow, a second portion to a second oxidant flow, and a third portion of the separated oxygen gas to the first, second, and third zones of the furnace. A controller can cause the separated oxygen gas to be distributed so that the first and second oxygen flows have a desired oxygen content, and so that the first, second, and third zones of the furnace receive a desired amount of oxygen based on a combustion zone stoichiometry control.

  3. Preparing General Purpose Forces in the United States and British Armies for Counterinsurgent Operations

    Science.gov (United States)

    2010-12-10

    commander whose book Learning to Eat Soup with a Knife, was widely read by military leaders serving in Afghanistan and Iraq. Dr. Nagl also...sustainment training for units while deployed to Malaya.23 Arthur Campbell , a company commander in the Suffolk Regiment who served in Malaya in the early 1950s...Learning to Eat Soup with a Knife: Counterinsurgency Lessons from Malaya and Vietnam, comparing the Malayan Emergency and Vietnam War is akin to

  4. Domestic Contingency Operations: A New Role for the United States Army

    Science.gov (United States)

    1993-06-04

    The addition of operations other than war to military lexicology greatly assists to define the role of the Army in support of domestic missions but...transportation, linguists , and health services directly translate to the domestic environment. This critical skills are essential for disaster

  5. Accomplishing Shipyard Work for the United States Navy: Institutions, Systems and Operations. Volume 3. Annotated Bibliography

    Science.gov (United States)

    1975-08-01

    operations research, advanced energy sources and propulsion technologies, nuclear physics, marine biology , maritime law, and ship financing. The...ductivity and reducing its production costs. 17 ()Determine whether -the industry c~ i achieve by FY 17 alevel of productivity that will allow reduction

  6. 40 CFR 63.1104 - Process vents from continuous unit operations: applicability assessment procedures and methods.

    Science.gov (United States)

    2010-07-01

    ... vent. (iv) Design analysis based on accepted chemical engineering principles, measurable process... be monitored to ensure the process vent is operated in conformance with its design or process and... 40 Protection of Environment 10 2010-07-01 2010-07-01 false Process vents from continuous...

  7. 75 FR 39707 - STP Nuclear Operating Company, South Texas Project, Units 1 and 2; Exemption

    Science.gov (United States)

    2010-07-12

    ... health physics or chemistry duties required as a member of the onsite emergency response organization's...). Other references include: NUREG-0654, ``Criteria for Preparation of and Evaluation of Radiological..., maintenance, health physics, chemistry and security to maintain the safe and secure operation of the facility...

  8. Giardia duodenalis assemblages in weaned cattle on cow-calf operations in the United States

    Science.gov (United States)

    To determine the prevalence of Giardia duodenalis in weaned beef calves in cow-calf operations, fecal specimens were collected from 819 6- to18-month-old calves in 20 states. After cleaning and concentrating cysts from feces, DNA was extracted from each specimen. The presence of G. duodenalis was de...

  9. Success in an Introductory Operations Research Course: A Case Study at the United Arab Emirates University

    Science.gov (United States)

    Yousef, Darwish Abdulrahman

    2009-01-01

    Purpose: The purpose of this paper is to examine the influence of a number of factors such as high school major, high school score, gender, Stat105, Maths I, Maths II grades, and grade point average (GPA) on students' academic performance in an introductory operations research (OR) course at the department of Business Administration--College of…

  10. 14 CFR 11.83 - How can I operate under an exemption outside the United States?

    Science.gov (United States)

    2010-01-01

    ... Organization (ICAO). If it would not, but we still believe it would be in the public interest to allow you to do so, we will file a difference with ICAO. However, a foreign country still may not allow you to operate in that country without meeting the ICAO standard....

  11. Virus removal retention challenge tests performed at lab scale and pilot scale during operation of membrane units.

    Science.gov (United States)

    Humbert, H; Machinal, C; Labaye, Ivan; Schrotter, J C

    2011-01-01

    The determination of the virus retention capabilities of UF units during operation is essential for the operators of drinking water treatment facilities in order to guarantee an efficient and stable removal of viruses through time. In previous studies, an effective method (MS2-phage challenge tests) was developed by the Water Research Center of Veolia Environnement for the measurement of the virus retention rates (Log Removal Rate, LRV) of commercially available hollow fiber membranes at lab scale. In the present work, the protocol for monitoring membrane performance was transferred from lab scale to pilot scale. Membrane performances were evaluated during pilot trial and compared to the results obtained at lab scale with fibers taken from the pilot plant modules. PFU culture method was compared to RT-PCR method for the calculation of LRV in both cases. Preliminary tests at lab scale showed that both methods can be used interchangeably. For tests conducted on virgin membrane, a good consistency was observed between lab and pilot scale results with the two analytical methods used. This work intends to show that a reliable determination of the membranes performances based on RT-PCR analytical method can be achieved during the operation of the UF units.

  12. Symptoms of psychological distress and post-traumatic stress disorder in United States Air Force "drone" operators.

    Science.gov (United States)

    Chappelle, Wayne L; McDonald, Kent D; Prince, Lillian; Goodman, Tanya; Ray-Sannerud, Bobbie N; Thompson, William

    2014-08-01

    The goal of this study is to repeat a survey administered in 2010 to assess for changes in mental health among United States Air Force aircrew operating Predator/Reaper remotely piloted aircraft, also commonly referred to as "drones." Participants were assessed for self-reported sources of occupational stress, levels of clinical distress using the Outcome Questionnaire-45.2, and symptoms of post-traumatic stress disorder (PTSD) using the PTSD Checklist-Military Version. A total of 1,094 aircrew responded to the web-based survey composed of the commercially available standardized instruments mentioned above. The survey also contained nonstandardized items asking participants to report the main sources of their occupational stress, as well as questions addressing demographics and work-related characteristics. The estimated response rate to the survey was 49%. Study results reveal the most problematic self-reported stressors are operational: low manning, extra duties/administrative tasks, rotating shift work, and long hours. The results also reveal 10.72% of operators self-reported experiencing high levels of distress and 1.57% reported high levels of PTSD symptomology. The results are lower than findings from the 2010 survey and from soldiers returning from Iraq and Afghanistan. Implications of the study and recommendations for United States Air Force line leadership and mental health providers are discussed.

  13. Integration of Snow Data from Remote Sensing into Operational Streamflow Forecasting in the Western United States

    Science.gov (United States)

    Bender, S.; Painter, T. H.; Miller, W. P.; Andreadis, K.

    2014-12-01

    The small watershed ecosystem as a unit of experimental manipulation and analysis has been a hallmark of the Hubbard Brook Experimental Forest for 60 years. Water and nutrient budgets of headwater catchments have been instrumental in advancing our understanding of the response of forested ecosystems to disturbances such as air pollution and land management. A limitation in the practice of this approach is that point-scale measurements are compiled to create catchment scale estimates of fluxes and stores, thus losing process information that could be gained from spatial patterns that depend on position along hydrologic or biogeochemical pathways. Beginning in 2007, high frequency measurements of water table fluctuation, made possible by inexpensive sensor technology, highlighted the previously underappreciated role of groundwater in these steep headwater catchments. Hydropedologic units (HPUs), identified by morphological differences in soil profiles, and reflecting distinct groundwater regimes, were defined and arranged along a generalized toposequence to describe a conceptual model which partitions spatial variation into predictable, repeatable landscape units. Stratification of point scale measurements of soil and water quality elucidates spatial patterns of variation and allows identification of hot spots, or zones of the catchment where certain processes prevail. Specific HPUs are associated with high rates of dissolved organic matter production, nitrification, denitrification and delivery of mineral weathering products to the surface. Moving beyond the small watershed, contrasting spatial patterns in surface water chemistry at the basin scale suggest differing prevalence of various HPUs among headwater catchments. Comparison of water quality patterns with HPU distribution allows identification of catchment properties responsible for regulation of water quality at the point to the catchment to the basin scales.

  14. [Vaccination against hepatitis B: 3 years' experience at the Latium Operative Unit].

    Science.gov (United States)

    Perroni, L; Mattioli, R; Ensoli, G; Albertoni, F; Duchini, B; Ungaro, P; Corsi, T

    1989-01-01

    A campaign against hepatitis B was launched in 1985 in Latium Region, Italy, aimed at hospital workers, newborns of HBsAg positive mothers, hemodialysis patients, thalassemics and hemophiliacs. Subsequently, since the beginning of 1987 other at risk categories were included, namely households of HBsAg positive carriers, subjects with accidental exposure to Hepatitis B virus (HBV) (i.e exposure to street syringes), health care personnel working outside the hospital setting such as dentists, private clinics and laboratory workers, etc. A protocol was defined by the Regional Epidemiologic Unit (Osservatorio Epidemiologico Regionale) in order to evaluate the immunogenicity and safety af the two plasma-derived (pd) vaccines registered in Italy, MSD and Pasteur, in field conditions. Subjects belonging to these at risk categories were distributed among 21 hospital based vaccination units, to which the two vaccines were randomly allocated. Subjects were considered eligible for vaccination if they were HBsAg negative and Anti-HBs negative or Anti-HBs positive at low titer i.e. less than 20 milli-International units per milliliter. Subjects with insulin dependent diabetes, chronic liver disease or known hypersensitivity to vaccine components were also excluded. Antibody response was checked at six months since the beginning of the vaccination, i.e. after two doses of the MSD and three doses of Pasteur vaccine and expressed in miU/ml by use of Hollinger formula. Pre-vaccination screening, vaccination and post-vaccination anti-HBs testing were offered free of charge.(ABSTRACT TRUNCATED AT 250 WORDS)

  15. Remedial Action Report for Operable Units 6-05 and 10-04, Phase III

    Energy Technology Data Exchange (ETDEWEB)

    R. P. Wells

    2007-08-15

    This Phase III remedial action report addresses the remediation of lead-contaminated soils found at the Security Training Facility STF-02 Gun Range at the Idaho National Laboratory Site. Phase I, consisting of developing and implementing institutional controls at Operble Unit 10-04 sites and developing and implementing Idaho National Laboratory Site-wide plans for both institutional controls and ecological monitoring, was addressed in a previous report. Phase II will remediate sites contaminated with trinitrotoluene and Royal Demolition Explosive. Phase IV will remediate hazards from unexploded ordnance.

  16. [Utilization of technological resources within the framework of operation of a Mobile Mental Health Unit].

    Science.gov (United States)

    Garoni, D; Sarantidis, D; Katsadoros, K

    2016-01-01

    Telepsychiatry was introduced in the early 1950's for the provision of mental health services from a distance. In 1990 the progress made in telecommunications technologies caused a significant expansion in telepsychiatry services. It can refer to store and forward technologies, interactive technologies, remote monitoring technologies and it is applied to contribute to the lift of restrictions placed on providing mental health services. Restrictions may exist due to geographic isolation, lack of specialized services, high cost of moving patients etc. The positive cost-benefit analysis and the reliability of diagnosis and efficacy of interventions through telepsychiatry have been documented in various research papers referring to a wide range of contexts such as prisons, remote areas, general and psychiatric hospitals. Since 2003 the Mobile Mental Health Unit of South- Eastern (SE) Cyclades has been using videoconferencing in order to provide mental health services in thirteen islands. This area shares many of the characteristics of remote areas such as residential dispersion, lack of mental health services and frequent lack of access to services in urban centers. Telepsychiatry in conjunction with physical presence of professionals was launched by the Mobile Mental Health Unit in order to provide assistance to the evaluation of patients, to therapeutic interventions, to medicine prescription, to crisis intervention, to psychoeducation of patients and their families and to the implementation of educational and administrative activities . The use of existing technology in combination with the development of human resources has enabled continuity of care, crisis intervention and avoidance of involuntary hospitalization for a significant number of persons. Moreover, it has improved cooperation and coordination between the interdisciplinary team and local authorities and agencies. When professionals located in different parts are collaborating via telepsychiatry it is

  17. 20 GHz Operation of an Asynchronous Wave-Pipelined RSFQ Arithmetic-Logic Unit

    Science.gov (United States)

    Filippov, Timur V.; Sahu, Anubhav; Kirichenko, Alex F.; Vernik, Igor V.; Dorojevets, Mikhail; Ayala, Christopher L.; Mukhanov, Oleg A.

    We have designed and tested at high frequency an RSFQ-based Arithmetic-Logic Unit (ALU), the critical component of an 8-bit RSFQ processor datapath. The ALU design is based on a Kogge-Stone adder and employs an asynchronous wave-pipelined approach scalable for wide datapath processors. The 8-bit ALU circuit was fabricated with HYPRES' standard 4.5 kA/cm2 process and consists of 7,950 Josephson junctions, including input and output interfaces. In this paper, we present chip design and high-speed test results for the 8-bit ALU circuit.

  18. Modeling and Control of Low Voltage Flexible Units for Enhanced Operation of Distribution Feeders

    DEFF Research Database (Denmark)

    Raboni, Pietro; Hu, Weihao; Chaudhary, Sanjay

    2013-01-01

    Battery (EVB) is proposed for providing primary regulation in grid connected mode and for hierarchically manage an islanded LV distribution feeder. The unit models are described and a novel EVB model directly based on manufacturer’s data is proposed and evaluated comparing its performances with Sim......PowerSystems library block. Moreover a voltage dependant power term is applied to the Voltage-Source Converter (VSC) control scheme of the EVB for improving the performances of the islanded feeder. The control is tested in case of under frequency and consequent load shedding occurring at the residential feeder...

  19. Shielding considerations for an operating room based intraoperative electron radiotherapy unit.

    Science.gov (United States)

    Mills, M D; Almond, P R; Boyer, A L; Ochran, T G; Madigan, W; Rich, T A; Dally, E B

    1990-05-01

    The leakage radiation characteristics of a dedicated intraoperative radiotherapy linear accelerator have been measured on a machine designed to minimize the shielding required to allow it to be placed in an operating room suite. The scattering foil design was optimized to produce a flat beam for the field sizes employed while generating minimal bremsstrahlung contamination over the available energy range. More lead shielding was used in the treatment head than is used in conventional accelerators. A small amount of borated polyethylene shielding was also employed since neutron production was present at measurable levels. The room shielding installed in the operating room was demonstrated to be adequate to treat at least 20 patients each month to an average dose of 20 Gy. The worst case exposure was found to be 73% maximum permissible exposure. Administrative control was required for adjoining areas when calibrations and maintenance were performed.

  20. Environmental Monitoring Plan United States Department of Energy Richland Operations Office. Revision 2

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-11-10

    This Environmental Monitoring Plan was prepared for the US Department of Energy`s (DOE`s) Richland Operations Office (RL) to implement the requirements of DOE Order 5400.1. According to the Order, each DOE site, facility, or activity that uses, generates, releases, or manages significant pollutants or hazardous materials shall prepare a written environmental monitoring plan covering two major activities: (1) effluent monitoring and (2) environmental surveillance. The plan is to contain information discussing the rationale and design criteria for the monitoring programs, sampling locations and schedules, quality assurance requirements, program implementation procedures, analytical procedures, and reporting requirements. The plan`s purpose is to assist DOE in the management of environmental activities at the Hanford Site and to help ensure that operations on the site are conducted in an environmentally safe and sound manner.

  1. Unit operations for gas-liquid mass transfer in reduced gravity environments

    Science.gov (United States)

    Pettit, Donald R.; Allen, David T.

    1992-01-01

    Basic scaling rules are derived for converting Earth-based designs of mass transfer equipment into designs for a reduced gravity environment. Three types of gas-liquid mass transfer operations are considered: bubble columns, spray towers, and packed columns. Application of the scaling rules reveals that the height of a bubble column in lunar- and Mars-based operations would be lower than terrestrial designs by factors of 0.64 and 0.79 respectively. The reduced gravity columns would have greater cross-sectional areas, however, by factors of 2.4 and 1.6 for lunar and Martian settings. Similar results were obtained for spray towers. In contract, packed column height was found to be nearly independent of gravity.

  2. Final Environmental Review United States Air Force Operational Capability Enhancement in Australia

    Science.gov (United States)

    2013-05-15

    structures such as defensive 9 positions and the railway used to service the base in WWII remain scattered throughout the 10 installation. While...practices, and leveraged the DoD NOISEMAP suite of computer-based modeling tools. The 24 suite primarily includes BaseOps, NMAP, the Advanced Acoustic ...because there are no acoustic reference data for the RQ-31 4 in the models. The T-45 was selected as the surrogate for RQ-4 run-up operations because

  3. United States Air Force F-35A Operational Basing Environmental Impact Statement. Volume 1

    Science.gov (United States)

    2013-09-01

    15 nm offshore. Hill AFB, Utah – Situated near the Great Salt Lake and the UTTR, Hill AFB supports two operational squadrons of F-16s (48 aircraft...except over the Duck Valley Indian Reservation) and also allow flare use with seasonal and altitude restrictions. Supersonic flight is also authorized...possession, import, export, transport, selling, purchase, barter, or offering for sale purchase or barter, any migratory bird, their eggs , parts, and

  4. Scalable Mobile Ad Hoc Network (MANET) to Enhance Situational Awareness in Distributed Small Unit Operations

    Science.gov (United States)

    2015-06-01

    on board holds only one program, and it is overwritten during the next upload. There are many different versions of boards that the company sells ...computing the algorithm is written in Python, a simple terminal programming language. At the top of that script was the integration to ROS and the rest of...pi-2-on- sale /. Accessed June 1, 2015. [25] Robotic Operating System (ROS) website (n.d.). ROS. [Online]. Available: http://www.ros.org/. Accessed

  5. Apollo’s Warriors: United States Air Force Special Operations during the Cold War

    Science.gov (United States)

    1997-01-01

    in South Vietnam, three at were made to Honduras, the Dominican Republic, Hurlburt Field, and one each in Panama and West Guatemala, Peru ...MCAO program. Force Military Civic Action Officer (MCAO) To the casual social observer, the ingredients for program conducted in Thailand received...Agent Orange issue. described Agent Orange as so powerful that The 12th Special Operations Squadron ( redes - "within two days [it] could topple a

  6. The Optimized Operation of Gas Turbine Combined Heat and Power Units Oriented for the Grid-Connected Control

    Science.gov (United States)

    Xia, Shu; Ge, Xiaolin

    2016-04-01

    In this study, according to various grid-connected demands, the optimization scheduling models of Combined Heat and Power (CHP) units are established with three scheduling modes, which are tracking the total generation scheduling mode, tracking steady output scheduling mode and tracking peaking curve scheduling mode. In order to reduce the solution difficulty, based on the principles of modern algebraic integers, linearizing techniques are developed to handle complex nonlinear constrains of the variable conditions, and the optimized operation problem of CHP units is converted into a mixed-integer linear programming problem. Finally, with specific examples, the 96 points day ahead, heat and power supply plans of the systems are optimized. The results show that, the proposed models and methods can develop appropriate coordination heat and power optimization programs according to different grid-connected control.

  7. Borehole Data Package for Nine CY 2006 Polyphosphate Treatability Testing Wells, 300-FF-5 Operable Unit, Hanford Site, Washington

    Energy Technology Data Exchange (ETDEWEB)

    Williams, Bruce A.

    2007-04-12

    Nine new CERCLA groundwater monitoring wells were installed in the 300-FF-5 Operable Unit in calendar year 2006 to fulfill commitments for the EM-20 funded polyphosphate treatability test. Nine new performance monitoring wells were drilled into the uppermost unconfined aquifer, to the Hanford formation - Ringold Formation contact boundary, and completed within the permeable Hanford fm. unit 1 gravel-dominated sequence. The overall objective of the polyphosphate treatability test is to evaluate the efficacy of using polyphosphate injections to treat 300 Area uranium contaminated groundwater in situ. The objective of this work was to install the performance monitoring network surrounding the existing treatability injection well C5000 (399-1-23) in support of the implementation of a field scale demonstration of the polyphosphate technology.

  8. Geological Factors Affecting Flow Spatial Continuity in Water Injection of Units Operating in the LGITJ–0102 Ore Body

    Directory of Open Access Journals (Sweden)

    Ilver M. Soto-Loaiza

    2016-05-01

    Full Text Available The objective of the investigation was to identify the geological factors affecting the spatial continuity of the flow during the process of flank water injection in the units operating in the Lower Lagunilla Hydrocarbon Ore Body. This included the evaluation of the recovery factor, the petro-physic properties such as porosity, permeability, water saturation and rock type and quality in each flow unit. it was observed that the rock type of the geologic structure in the ore body is variable. The lowest values for the petro-physic properties were found in the southern area while a high variability of these parameters was observed in the northern and central areas. It was concluded that the northern area has a great potential for the development of new injection projects for petroleum recovery.

  9. THE FINANCING OF THE ADMINISTRATIVE TERRITORIAL UNITS IN THE WEST DEVELOPMENT REGION THROUGH THE REGIONAL OPERATIONAL PROGRAMME 2007 - 2013

    Directory of Open Access Journals (Sweden)

    Munteanu Nicolae-Eugen

    2011-07-01

    Full Text Available It is very important to be found methods to increase the competitiveness between the Romanian administrative-territorial units, under the current conditions of the economic crisis, by means of the existing economic levers successfully used within the European Union regions. The development regions of Romania do not have the statute of administrative units, but they represent territorial units large enough to constitute a good basis for the elaboration and implementation of regional development strategies, allowing an efficient use of the financial and human resources. The scope for which these development regions were created had in view the support granted for the larger communities in their action to settle the problems which go beyond the administrative borders and which surpass the financial possibilities of one county. In Romania, the communes, towns, municipalities and counties are defined as administrative-territorial units within which the local autonomy is exercised and the authorities of the local public administration are organized and operate. The local, communal, town, municipality and county councils, as deliberative authorities, and also the mayors and the presidents of county councils as executive authorities have the duties to solve the public matters of the community, acting as authorities of the Romanian public administration. In Romania, the local autonomy is only administrative and financial, having as objective the organization, operation, competencies and tasks, and also the management of the inland resources. The principle of the local financial autonomy implies the fact that the administrative-territorial units have the right to financial resources, which can be used by the authorities of the local public administration when exercising their tasks. According to the Law of the local public finances, the local budget incomes could be made also of the non-reimbursable funds granted by the European Union. Based on the

  10. Isolation and quarantine during pandemic (H1N1) 2009 influenza in NSW: the operational experience of public health units.

    Science.gov (United States)

    Binns, Philippa L; Sheppeard, Vicky; Staff, Michael P

    2010-01-01

    During the DELAY and CONTAIN phases of pandemic (H1N1) 2009 influenza in NSW, public health units needed to rapidly surge operations to manage the 3070 potential cases and 1894 contacts notified to them. The Incident Control System, NetEpi (the web-based multi-user access database), training to up-skill surge staff, and electronic communication were all integral to the outbreak response. Ongoing identification and training of surge staff would assist a timely and effective response to future large scale outbreaks. Investing and incorporating information technology tools into routine public health unit business to assist with communication, outbreak management and reporting will improve familiarity and capability within the network to respond to public health emergencies.

  11. Evaluation of incidence and severity of postoperative hypoxemia in neurosurgical patients during transportation from operation theater to surgical intensive care unit in a tertiary care unit, Kashmir, India

    Directory of Open Access Journals (Sweden)

    Abdul Waheed Mir

    2012-07-01

    Full Text Available Background:Postoperative hypoxemia during transportation from operation theater to intensive care unit is common among neurosurgical patients. Methadology: Arterial oxygen saturation (Spo2 and arterial blood gas analysis was performed postoperatively before and after shifting a group of sixty patients with ASA I and ASA II status undergoing various elective neurosurgical procedures under general anesthesia at Sheri-Kashmir Institute of Medical Sciences Srinagar , Kashmir. Statistical analysis: The data was analyzed using SPSS version 13. The chi-square test was used for categorical variables and student’s t test was used for continuous variables with normal distribution. The data was collected, compiled and statistically analyzed using analysis of variance (ANOVA. The values were expressed as mean±SD and a p value <0.05 was taken as statistically significant. Results: SpO2 before and after transporting the patients to SICU in group I was 98.90±0.45 and 86.70±3.85 respectively, whereas in group II, the SpO2 values were 98.80±0.52 and 93.95±3.99 respectively. In group III the mean SpO2 before and after transportation was 97.60±1.96 and 83.95±8.64 respectively. The difference in SpO2 in all the three groups before and after transportation was statistically significant (p<0.05. Conclusion: We recommend supplemental oxygen administration in all neurosurgical patients during transportation from operation theater to intensive care unit.

  12. Depot medroxyprogesterone (Depo-Provera) and risk of breast cancer.

    Science.gov (United States)

    Paul, C.; Skegg, D. C.; Spears, G. F.

    1989-01-01

    OBJECTIVE--To determine whether use of the injectable contraceptive depot medroxyprogesterone acetate (Depo-Provera) affects the risk of breast cancer in women. DESIGN--A population based case-control study. SETTING--Nationwide community study. SUBJECTS--891 Women aged 25-54 with newly diagnosed breast cancer were compared with 1864 women selected at random from the electoral rolls. INTERVENTION--Women were interviewed by telephone about past use of contraceptives and about possible risk factors for breast cancer. MAIN OUTCOME MEASURE--Relative risk of breast cancer in women who had used medroxyprogesterone. RESULTS--Medroxyprogesterone had been used by 110 patients and 252 controls. Overall, the relative risk of breast cancer associated with any duration of use was 1.0 (95% confidence interval 0.80 to 1.3). In women aged 25-34 the relative risk was 2.0 (1.0 to 3.8). The relative risk was highest in women aged 25-34 who had used the drug for six years or longer, although there were few women in this category. Women who had used it for two years or longer before age 25 had an increased risk of breast cancer (relative risk 4.6; 1.4 to 15.1). CONCLUSION--Despite the lack of an overall association these findings suggest that medroxyprogesterone may increase the risk of breast cancer in young women. PMID:2529939

  13. Depot-specific Regulation of the Conversion of Cortisone to Cortisol in Human Adipose Tissue

    Science.gov (United States)

    Lee, Mi-Jeong; Fried, Susan K.; Mundt, Steven S.; Wang, Yanxin; Sullivan, Sean; Stefanni, Alice; Daugherty, Bruce L.; Hermanowski-Vosatka, Anne

    2015-01-01

    Objective Our main objective was to compare the regulation of cortisol production within omental (Om) and abdominal subcutaneous (Abd sc) human adipose tissue. Methods and Procedures Om and Abd sc adipose tissue were obtained at surgery from subjects with a wide range of BMI. Hydroxysteroid dehydrogenase (HSD) activity (3H-cortisone and 3H-cortisol interconversion) and expression were measured before and after organ culture with insulin and/or dexamethasone. Results Type 1 HSD (HSD1) mRNA and reductase activity were mainly expressed within adipocytes and tightly correlated with adipocyte size within both depots. There was no depot difference in HSD1 expression or reductase activity, while cortisol inactivation and HSD2 mRNA expression (expressed in stromal cells) were higher in Om suggesting higher cortisol turnover in this depot. Culture with insulin decreased HSD reductase activity in both depots. Culture with dexamethasone plus insulin compared to insulin alone increased HSD reductase activity only in the Om depot. This depot-specific increase in reductase activity could not be explained by an alteration in HSD1 mRNA or protein, which was paradoxically decreased. However, in Om only, hexose-6-phosphate dehydrogenase (H6PDH) mRNA levels were increased by culture with dexamethasone plus insulin compared to insulin alone, suggesting that higher nicotinamide adenine dinucleotide phosphate-oxidase (NADPH) production within the endoplasmic reticulum (ER) contributed to the higher HSD reductase activity. Discussion We conclude that in the presence of insulin, glucocorticoids cause a depot-specific increase in the activation of cortisone within Om adipose tissue, and that this mechanism may contribute to adipocyte hypertrophy and visceral obesity. PMID:18388900

  14. Measurement of ground and nearby building vibration and noise induced by trains in a metro depot.

    Science.gov (United States)

    Zou, Chao; Wang, Yimin; Wang, Peng; Guo, Jixing

    2015-12-01

    Metro depots are where subway trains are parked and where maintenance is carried out. They usually occupy the largest ground areas in metro projects. Due to land utilization problems, Chinese cities have begun to develop over-track buildings above metro depots for people's life and work. The frequently moving trains, when going into and out of metro depots, can cause excessive vibration and noise to over-track buildings and adversely affect the living quality of the building occupants. Considering the current need of reliable experimental data for the construction of metro depots, field measurements of vibration and noise on the ground and inside a nearby 3-story building subjected to moving subway trains were conducted in a metro depot at Guangzhou, China. The amplitudes and frequency contents of velocity levels were quantified and compared. The composite A-weighted equivalent sound levels and maximum sound levels were captured. The predicted models for vibration and noise of metro depot were proposed based on existing models and verified. It was found that the vertical vibrations were significantly greater than the horizontal vibrations on the ground and inside the building near the testing line. While at the throat area, the horizontal vibrations near the curved track were remarkably greater than the vertical vibrations. The attenuation of the vibrations with frequencies above 50 Hz was larger than the ones below 50 Hz, and the frequencies of vibration transmitting to adjacent buildings were mainly within 10-50 Hz. The largest equivalent sound level generated in the throat area was smaller than the testing line one, but the instantaneous maximum sound level induced by wheels squeal, contact between wheels and rail joints as well as turnout was close to or even greater than the testing line one. The predicted models gave a first estimation for design and assessment of newly built metro depots.

  15. Evaluation of potential severe accidents during low power and shutdown operations at Surry: Unit 1, Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    Chu, T.L.; Pratt, W.T. [eds.; Musicki, Z. [Brookhaven National Lab., Upton, NY (United States)

    1995-10-01

    This document contains a summarization of the results and insights from the Level 1 accident sequence analyses of internally initiated events, internally initiated fire and flood events, seismically initiated events, and the Level 2/3 risk analysis of internally initiated events (excluding fire and flood) for Surry, Unit 1. The analysis was confined to mid-loop operation, which can occur during three plant operational states (identified as POSs R6 and R10 during a refueling outage, and POS D6 during drained maintenance). The report summarizes the Level 1 information contained in Volumes 2--5 and the Level 2/3 information contained in Volume 6 of NUREG/CR-6144.

  16. Remedial investigation/feasibility study of the Clinch River/Poplar Creek operable unit. Volume 5

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-01

    This volume is in support of the findings of an investigation into contamination of the Clinch River and Poplar Creek near the Oak Ridge Reservation (for more than 50 years, various hazardous and radioactive substances have been released to the environment as a result of operations and waste management activities there). It addresses the quality assurance objectives for measuring the data, presents selected historical data, contains data from several discrete water characterization studies, provides data supporting the sediment characterization, and contains data related to several biota characterization studies.

  17. Analysis of hot spots in boilers of organic Rankine cycle units during transient operation

    DEFF Research Database (Denmark)

    Benato, A.; Kærn, Martin Ryhl; Pierobon, Leonardo

    2015-01-01

    This paper is devoted to the investigation of critical dynamic events causing thermochemical decompositionof the working fluid in organic Rankine cycle power systems. The case study is the plant of an oiland gas platform where one of the three gas turbines is combined with an organic Rankine cycle...... and fluid decomposition. It is demonstrated thatthe use of a spray attemperator can mitigate the problems of local overheating of the organic compound.As a practical consequence, this paper provides guidelines for safe and reliable operation of organicRankine cycle power modules on offshore installations....

  18. An Analysis of Post-Traumatic Stress Symptoms in United States Air Force Drone Operators

    Science.gov (United States)

    2014-05-17

    the assessment, and variability of combat exposure. Otto and Webber (2013) noted that the incidence of mental health problems among USAF drone operators...to complete a demographics and occupational questionnaire composed of several items that assessed gender, age range, rank range, marital status...18–25 222 20.48 26–30 363 33.49 31–34 182 16.79 35–39 150 13.84 40+ 165 15.22 Missing 2 ə MAJCOM AFSOC 140 12.92 ANG 217 20.02 ACC 727 67.07 Rank

  19. Organizational structure and operation of defense/aerospace information centers in the United States of America

    Science.gov (United States)

    Sauter, H. E.; Lushina, L. N.

    1983-01-01

    U.S. Government aerospace and defense information centers are addressed. DTIC and NASA are described in terms of their history, operational authority, information services provided, user community, sources of information collected, efforts under way to improve services, and external agreements regarding the exchange of documents and/or data bases. Contents show how DTIC and NASA provide aerospace/defense information services in support of U.S. research and development efforts. In a general introduction, the importance of scientific and technical information and the need for information centers to acquire, handle, and disseminate it are stressed.

  20. Waste Area Group 10, Operable Unit 10-08, Remedial Investigation/Feasibility Study Annual Status Report for Fiscal Year 2006

    Energy Technology Data Exchange (ETDEWEB)

    R. P. Wells

    2007-05-09

    This report provides a status of the progress made in Fiscal Year 2006 on tasks identified in the Waste Area Group 10, Operable Unit 10-08, Remedial Investigation/Feasibility Study Work Plan. Major accomplishments include: (1) groundwater sampling and review of the groundwater monitoring data, (2) installation of a Sitewide groundwater-level monitoring network, (3) update of the Groundwater Monitoring and Field Sampling Plan of Operable Unit 10-08, (4) re-evaluation of the risk at Site TSF-08, (5) progress on the Operable Unit 10-08 Sitewide Groundwater Model.

  1. ANNUAL REPORT FOR THE FINAL GROUNDWATER REMEDIATION, TEST AREA NORTH, OPERABLE UNIT 1-07B, FISCAL YEAR 2009

    Energy Technology Data Exchange (ETDEWEB)

    FORSYTHE, HOWARD S

    2010-04-14

    This Annual Report presents the data and evaluates the progress of the three-component remedy implemented for remediation of groundwater contamination at Test Area North, Operable Unit 1-07B, at the Idaho National Laboratory Site. Overall, each component is achieving progress toward the goal of total plume remediation. In situ bioremediation operations in the hot spot continue to operate as planned. Progress toward the remedy objectives is being made, as evidenced by continued reduction in the amount of accessible residual source and decreases in downgradient contaminant flux, with the exception of TAN-28. The injection strategy is maintaining effective anaerobic reductive dechlorination conditions, as evidenced by complete degradation of trichloroethene and ethene production in the biologically active wells. In the medial zone, the New Pump and Treat Facility operated in standby mode. Trichloroethene concentrations in the medial zone wells are significantly lower than the historically defined concentration range of 1,000 to 20,000 μg/L. The trichloroethene concentrations in TAN-33, TAN-36, and TAN-44 continue to be below 200 μg/L. Monitoring in the distal zone wells outside and downgradient of the plume boundary demonstrate that some plume expansion has occurred, but less than the amount allowed in the Record of Decision Amendment. Additional data need to be collected for wells in the monitored natural attenuation part of the plume to confirm that the monitored natural attenuation part of the remedy is proceeding as predicted in the modeling.

  2. Traumatic Brain Injury in United States Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) Hispanic Veterans-A Review Using the PRISMA Method.

    Science.gov (United States)

    Arriola, Vanessa D; Rozelle, Jeffrey W

    2016-01-12

    Traumatic brain injury (TBI) is commonly defined by Menon et al. as an "alteration of the brain function, or other evidence of brain pathology, caused by an external force." TBI can be caused by penetrating trauma to the head in which the magnitude of the injury is dependent on the magnitude of the forces that are applied to the head. The consequences of TBI can range from minimal to severe disability and even death. The major objectives of this systematic review are to survey the current literature on Operation Enduring Freedom (OEF) and Operation Iraqi Freedom (OIF) Hispanic veterans with TBI. To complete this analysis, the Preferred Reporting Items for Systematic Reviews and MetaAnalysis (PRISMA) identified 875 articles in common and retrieved a total of 34 articles that met the inclusion criteria, consisted of OEF/OIF Hispanic veterans, reported quantitative data, and were conducted with adult U.S. veterans living in the United States. Since TBI diagnosis was unclear in most articles, only five articles that used the VATBIST instrument were analyzed. The results suggested that there is a lack of research on OEF/OIF Hispanic veterans and Hispanic subgroups. Future studies need to be conducted to consider minority groups while analyzing data involving TBI.

  3. Traumatic Brain Injury in United States Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF Hispanic Veterans—A Review Using the PRISMA Method

    Directory of Open Access Journals (Sweden)

    Vanessa D. Arriola

    2016-01-01

    Full Text Available Traumatic brain injury (TBI is commonly defined by Menon et al. as an “alteration of the brain function, or other evidence of brain pathology, caused by an external force.” TBI can be caused by penetrating trauma to the head in which the magnitude of the injury is dependent on the magnitude of the forces that are applied to the head. The consequences of TBI can range from minimal to severe disability and even death. The major objectives of this systematic review are to survey the current literature on Operation Enduring Freedom (OEF and Operation Iraqi Freedom (OIF Hispanic veterans with TBI. To complete this analysis, the Preferred Reporting Items for Systematic Reviews and MetaAnalysis (PRISMA identified 875 articles in common and retrieved a total of 34 articles that met the inclusion criteria, consisted of OEF/OIF Hispanic veterans, reported quantitative data, and were conducted with adult U.S. veterans living in the United States. Since TBI diagnosis was unclear in most articles, only five articles that used the VATBIST instrument were analyzed. The results suggested that there is a lack of research on OEF/OIF Hispanic veterans and Hispanic subgroups. Future studies need to be conducted to consider minority groups while analyzing data involving TBI.

  4. Analysis of hot spots in boilers of organic Rankine cycle units during transient operation

    DEFF Research Database (Denmark)

    Benato, A.; Kærn, Martin Ryhl; Pierobon, Leonardo;

    2015-01-01

    for single- and two-phase heat transfer coefficients.The results indicate that severe load changes (0.4–1.0 MWs-1) can lead to exceedance of thetemperature limit of fluid decomposition for a period of 10 min. Ramp rates lower than 0.3MWs-1 areacceptable considering the stability of the electric grid......This paper is devoted to the investigation of critical dynamic events causing thermochemical decompositionof the working fluid in organic Rankine cycle power systems. The case study is the plant of an oiland gas platform where one of the three gas turbines is combined with an organic Rankine cycle...... and fluid decomposition. It is demonstrated thatthe use of a spray attemperator can mitigate the problems of local overheating of the organic compound.As a practical consequence, this paper provides guidelines for safe and reliable operation of organicRankine cycle power modules on offshore installations....

  5. Impact of computerized information systems on workload in operating room and intensive care unit.

    Science.gov (United States)

    Bosman, R J

    2009-03-01

    The number of operating rooms and intensive care departments equipped with a clinical information system (CIS) is rapidly expanding. Amongst the putative advantages of such an installation, reduction in workload for the clinician is one of the most appealing. The scarce studies looking at workload variations associated with the implementation of a CIS, only focus on direct workload discarding indirect changes in workload. Descriptions of the various methods to quantify workload are provided. The hypothesis that a third generation CIS can reduce documentation time for ICU nurses and increase time they spend on patient care, is supported by recent literature. Though it seems obvious to extrapolate these advantages of a CIS to the anesthesiology department or physicians in the intensive care, studies examining this assumption are scarce.

  6. The US Air Force Aerial Spray Unit: a history of large area disease vector control operations, WWII through Katrina.

    Science.gov (United States)

    Breidenbaugh, Mark; Haagsma, Karl

    2008-01-01

    The US Air Force has had a long history of aerial applications of pesticides to fulfill a variety of missions, the most important being the protection of troops through the minimization of arthropod vectors capable of disease transmission. Beginning in World War II, aerial application of pesticides by the military has effectively controlled vector and nuisance pest populations in a variety of environments. Currently, the military aerial spray capability resides in the US Air Force Reserve (USAFR), which operates and maintains C-130 airplanes capable of a variety of missions, including ultra low volume applications for vector and nuisance pests, as well as higher volume aerial applications of herbicides and oil-spill dispersants. The USAFR aerial spray assets are the only such fixed-wing aerial spray assets within the Department of Defense. In addition to troop protection, the USAFR Aerial Spray Unit has participated in a number of humanitarian/relief missions, most recently in the response to the 2005 Hurricanes Katrina and Rita, which heavily damaged the Gulf Coasts of Louisiana, Mississippi, and Texas. This article provides historical background on the Air Force Aerial Spray Unit and describes the operations in Louisiana in the aftermath of Hurricane Katrina.

  7. Trends in operative experience of pediatric surgical residents in the United States and Canada.

    Science.gov (United States)

    Fingeret, Abbey L; Stolar, Charles J H; Cowles, Robert A

    2013-01-01

    Expansion of the number of training programs in pediatric surgery occurred from 2003 through 2010. We sought to determine the effect of program expansion on case volume and distribution of operative experience. Public domain data on pediatric surgery resident summary statistics available from the Accreditation Council for Graduate Medical Education (ACGME) from July 2003 through June 2010 were analyzed. Total case volume as primary surgeon or teaching assistant, mean case volume per resident, standard deviation, mode, minimum, and maximum number of cases per resident were evaluated. Mean total cases per resident, minimally invasive laparoscopic and thoracoscopic cases, and requisite cases as defined by the ACGME categories of: tumor, important pediatric surgical, and neonatal cases were analyzed by a Cuzick Wilcoxon-type nonparametric trend statistic using a significance level of 0.05. Skew was assessed by Pearson coefficient with levels of -0.5 to 0.5 defining a parametric distribution. The number of pediatric surgical training residents increased by 42% during the years reported, from 24 to 34. No statistically significant difference was found in the mean number of total cases or requisite cases per resident. The mean volume of minimally invasive procedures increased significantly. Case volume per resident was non-parametrically distributed with increasing positive skew over time. The increase in number of pediatric surgical resident training positions has not adversely affected overall operative experience or exposure to highly specialized requisite cases, on average. The increasing positive skew of total and index cases, however, suggests that variability between programs in case exposure is increasing over time. Copyright © 2013 Elsevier Inc. All rights reserved.

  8. The Vertebrate Brain, Evidence of Its Modular Organization and Operating System: Insights into the Brain's Basic Units of Structure, Function, and Operation and How They Influence Neuronal Signaling and Behavior.

    Science.gov (United States)

    Baslow, Morris H

    2011-01-01

    The human brain is a complex organ made up of neurons and several other cell types, and whose role is processing information for use in eliciting behaviors. However, the composition of its repeating cellular units for both structure and function are unresolved. Based on recent descriptions of the brain's physiological "operating system", a function of the tri-cellular metabolism of N-acetylaspartate (NAA) and N-acetylaspartylglutamate (NAAG) for supply of energy, and on the nature of "neuronal words and languages" for intercellular communication, insights into the brain's modular structural and functional units have been gained. In this article, it is proposed that the basic structural unit in brain is defined by its physiological operating system, and that it consists of a single neuron, and one or more astrocytes, oligodendrocytes, and vascular system endothelial cells. It is also proposed that the basic functional unit in the brain is defined by how neurons communicate, and consists of two neurons and their interconnecting dendritic-synaptic-dendritic field. Since a functional unit is composed of two neurons, it requires two structural units to form a functional unit. Thus, the brain can be envisioned as being made up of the three-dimensional stacking and intertwining of myriad structural units which results not only in its gross structure, but also in producing a uniform distribution of binary functional units. Since the physiological NAA-NAAG operating system for supply of energy is repeated in every structural unit, it is positioned to control global brain function.

  9. 蒙华铁路货车段修能力探讨%Discussion on Freight Train Maintenance Capacity in Depot for Western Inner Mongolia-to-Central China Railway

    Institute of Scientific and Technical Information of China (English)

    骆礼伦; 缪东

    2014-01-01

    阐述客货分线后铁路货运能力增强、货车保有量增长的特征,以及铁路货物高效率高质量的运输需求,必然会对货车段修能力提出新的要求。采用调研货车保有量、货车段修台位方法,结合货车保有量预测,分析全路及蒙西至华中煤运通道铁路(简称“蒙华铁路”)沿线区域内货车保有量增长与货车段修能力的矛盾,提出新建(或扩建)车辆段、加强检修工艺装备、优化组织管理、修程修制改革等货车段修能力增强措施,提出蒙华铁路货车车辆段(检修车间)设施布局方案,分析沿线区域货车段修能力增强措施。%This paper pointed out that after separated operation between railway passenger and freight transportations, the railway freight transportation capacity would be improved and the reserves of freight trains would be increased; and then the need of high efficiency and high quality of railway freight transportation would be bound to make demand on the freight train maintenance capacity in depot. In this paper, by means of investigation on the reserves of freight trains and depot repair bays, and in combination with the prediction on the reserves of freight trains, the conflicts between the freight train's growth and the freight train maintenance capacity in depot was analyzed for the whole railways and for the Western Inner Mongolia-to-Central China Railway which would be used for coal transportation. Furthermore, this paper proposed the measures to improve the freight train maintenance capacity in depot, such as building new ( or expanding ) freight train depots, enhancing repairing technical equipment, optimizing organization management, reforming repair schedule and repair regulations, and so on. Finally, this paper proposed a scheme of facility layout in the freight train depots ( or repairing workshops) for Western Inner Mongolia-to-Central China Railway, and analyzed the measures for improving the

  10. Predictability of Operant Behavior of Rats by Prefrontal Multiple Unit Activities

    Science.gov (United States)

    Fujiwara, Sei-Etsu; Akema, Tatsuo; Izaki, Yoshinori

    To investigate the possibility of a brain computer interface (BCI) constructed using activities of the prefrontal cortex (PFC), we analyzed PFC multiple unit activities (MUAs) during a delayed reinforcement (DRF) lever press task in rats. In the DRF task, each trial consisted of two lever press responses (R1, R2): R1 as the trial initiation, R2 as a pre-conditioned response to a stimulus (buzzer) for a reward. Between R1 and the buzzer, rats were required to inhibit the lever press (waiting phase). The trial was evaluated as incorrect if rats pressed the lever during the waiting phase. Results show that the mean firing rate (MFR) was significantly lower around the time of R1 compared with the pre-trial time in correct trials, although no significant changes were found in incorrect trials. From a neuroengineering perspective, the MFR of each single trial was calculated. Most correct trials showed decreasing MFR around the time of R1. The PFC MUA might be useful for BCI.

  11. Major Problems Related with Operation of Catalytic Reforming Units and Countermeasures

    Institute of Scientific and Technical Information of China (English)

    Zhou Jianhua

    2006-01-01

    @@ Currently the catalytic reforming units are playing an increasingly important role for gasoline quality upgrading, increased production of high add-value aromatic compounds and supply of cheap hydrogen resources. The high proportion of FCC gasoline in China' s automotive gasoline pool has led to a quite significant gap in gasoline quality as compared to the demand of World Fuel Charter and even to the new Chinese standards for unleaded automotive gasoline. According to the statistical data, the ratio of FCC naphtha in the gasoline pool is 35% in the US and 27% in EU, whereas that number is 75% in China's gasoline pool. The share of reformate and other high-quality gasoline components in the gasoline pool is 65% in the US and 73% in EU, whereas that number is merely 14% in China's gasoline pool along with a definite share of low-octane (straight-run) gasoline. Therefore, devoting major efforts to the development of catalytic reforming technology to increase the output of high-octane, lowolefin and low-sulfur reformer gasoline component is an effective avenue for gasoline quality upgrading along with increased production of high add-value aromatics and cheap hydrogen.

  12. [Ethics consultation unit in nephrology (UCEN): review of 10 years of operation in the Grenoble area].

    Science.gov (United States)

    Maurizi Balzan, Jocelyne; Moreaud, Olivier; Palacin, Pedro; Truche, Anne-Sophie; Zaoui, Philippe

    2013-07-01

    The existence of an ethics consultation unit in nephrology (UCEN) gives to the nephrologist the collegiality required to meet the difficulties of therapeutic choice on a legislative level, particularly in indications of stop dialysis. The discussion conducted, outside the emergency, is guided by a tool for reflexion that details successive steps necessary to the identification of elements required for decision-making. Thanks to complementary skills provided by the participants and training acquired, the UCEN can approach other ethic issues encountered during practice such as contrindication for a kidney transplantation or maintenance of conservative treatment, or performing invasive procedures on patients refusing transfusion. Propositions are not always relevant due to opposition or ambivalence of some patients, their relatives, an external or disagreements between teams or a mismatch between the technical and the patient's condition. These non-conformities decrypted always have an explanation, sometimes they are understood and accepted by the teams, and sometimes they became source of regrets when they extend life in very poor conditions. The UCEN, if it does not solve every single point, remains a place and a time of sharing that face difficult situations, help the nephrologist positioning himself on maintaining treatments that were first to avoid and prevent the realization of unreasonable acts and accept their limits.

  13. Space Resource Requirements for Future In-Space Propellant Production Depots

    Science.gov (United States)

    Smitherman, David; Fikes, John; Roy, Stephanie; Henley, Mark W.; Potter, Seth D.; Howell, Joe T. (Technical Monitor)

    2001-01-01

    In 2000 and 2001 studies were conducted at the NASA Marshall Space Flight Center on the technical requirements and commercial potential for propellant production depots in low Earth orbit (LEO) to support future commercial, NASA, and other Agency missions. Results indicate that propellant production depots appear to be technically feasible given continued technology development, and there is a substantial growing market that depots could support. Systems studies showed that the most expensive part of transferring payloads to geosynchronous orbit (GEO) is the fuel. A cryogenic propellant production and storage depot stationed in LEO could lower the cost of missions to GEO and beyond. Propellant production separates water into hydrogen and oxygen through electrolysis. This process utilizes large amounts of power, therefore a depot derived from advanced space solar power technology was defined. Results indicate that in the coming decades there could be a significant demand for water-based propellants from Earth, moon, or asteroid resources if in-space transfer vehicles (upper stages) transitioned to reusable systems using water based propellants. This type of strategic planning move could create a substantial commercial market for space resources development, and ultimately lead toward significant commercial infrastructure development within the Earth-Moon system.

  14. Neuroendocrine Tumors and Lanreotide Depot: Clinical Considerations and Nurse and Patient Preferences.

    Science.gov (United States)

    Ryan, Pamela; Phan, Alexandria T; Adelman, Daphne T; Iwasaki, Michiko

    2016-12-01

    Somatostatin analogs (SSAs) are a mainstay therapy for the treatment of carcinoid syndrome associated with neuroendocrine tumors (NETs). They are effective for a range of gastroenteropancreatic NETs (GEP-NETs). Lanreotide depot (Somatuline®) is an SSA that is approved for the treatment of GEP-NETs to improve progression-free survival (PFS). The article reviews the efficacy, safety, and administration of lanreotide depot and relates those attributes to considerations and preferences of oncology nurses and their patients. A review of the literature on the use of lanreotide for the treatment of NETs and carcinoid syndrome was conducted. In addition, the literature on drug delivery and routes of administration was surveyed to provide context for comparative studies related to clinical and patient preferences. Lanreotide depot prolongs PFS and is well tolerated by patients who expressed satisfaction in the ability to control symptoms related to carcinoid syndrome. Nurses cited several benefits to using lanreotide depot in the clinical setting, including more time saved to address other patient care issues. Attributes of lanreotide depot-including its efficacy, safety and tolerability, dosing and administration, and cost-may contribute to healthcare decisions regarding the treatment and management of NETs.

  15. Depot specific differences during adipogenesis of porcine stromal-vascular cells.

    Science.gov (United States)

    Samulin, Johanna; Lien, Sigbjørn; Grindflek, Eli; Berget, Ingunn; Ruyter, Bente; Sundvold, Hilde

    2008-05-01

    Recently a role of adipose tissue as an endocrine organ secreting factors involved in the regulation of whole-body energy homeostasis has emerged. Preadipocytes in different fat depots have distinct adipogenic potential and the metabolic activity differs between mature adipocytes of different depot origins. Here we describe the proliferation and differentiation of stromal-vascular cells derived from subcutaneous and visceral fat depots of adult pigs. We demonstrate that subcutaneous porcine preadipocytes proliferate more actively and that individual subcutaneous adipocytes have a more rapid accumulation of triacylglycerols than visceral cells. During differentiation, subcutaneous and visceral preadipocytes showed similar gene expression patterns with increased expression of adiponectin (APM1), adipocyte-specific fatty acid binding protein (FABP4), catalase (CAT), and peroxisome proliferator-activated receptor gamma 2 (PPARG2). Furthermore, initial data showing depot-originated effects on the expression of CAT, carnitine palmitoyl transferase 1B (CPT1B) and FABP4 suggest possible depot specific differences in the function and metabolism of mature porcine adipocytes.

  16. The price of surgery: markup of operative procedures in the United States.

    Science.gov (United States)

    Gani, Faiz; Makary, Martin A; Pawlik, Timothy M

    2017-02-01

    Despite cost containment efforts, the price for surgery is not subject to any regulations. We sought to characterize and compare variability in pricing for commonly performed major surgical procedures across the United States. Medicare claims corresponding to eight major surgical procedures (aortic aneurysm repair, aortic valvuloplasty, carotid endartectomy, coronary artery bypass grafting, esophagectomy, pancreatectomy, liver resection, and colectomy) were identified using the Medicare Provider Utilization and Payment Data Physician and Other Supplier Public Use File for 2013. For each procedure, total charges, Medicare-allowable costs, and total payments were recorded. A procedure-specific markup ratio (MR; ratio of total charges to Medicare-allowable costs) was calculated and compared between procedures and across states. Variation in MR was compared using a coefficient of variation (CoV). Among all providers, the median MR was 3.5 (interquartile range: 3.1-4.0). MR was noted to vary by procedure; ranging from 3.0 following colectomy to 6.0 following carotid endartectomy (P < 0.001). MR also varied for the same procedure; varying the least after liver resection (CoV = 0.24), while coronary artery bypass grafting pricing demonstrated the greatest variation in MR (CoV = 0.53). Compared with the national average, MR varied by 36% between states ranging from 1.8 to 13.0. Variation in MR was also noted within the same state varying by 15% within the state of Arkansas (CoV = 0.15) compared with 51% within the state of Wisconsin (CoV = 0.51). Significant variation was noted for the price of surgery by procedure as well as between and within different geographical regions. Greater scrutiny and transparency in the price of surgery is required to promote cost containment. Copyright © 2016 Elsevier Inc. All rights reserved.

  17. Mapping the solid-state properties of crystalline lysozyme during pharmaceutical unit-operations.

    Science.gov (United States)

    Mohammad, Mohammad Amin; Grimsey, Ian M; Forbes, Robert T

    2015-10-10

    Bulk crystallisation of protein therapeutic molecules towards their controlled drug delivery is of interest to the biopharmaceutical industry. The complexity of biotherapeutic molecules is likely to lead to complex material properties of crystals in the solid state and to complex transitions. This complexity is explored using batch crystallised lysozyme as a model. The effects of drying and milling on the solid-state transformations of lysozyme crystals were monitored using differential scanning calorimetry (DSC), X-ray powder diffraction (XRPD), FT-Raman, and enzymatic assay. XRPD was used to characterise crystallinity and these data supported those of crystalline lysozyme which gave a distinctive DSC thermogram. The apparent denaturation temperature (Tm) of the amorphous lysozyme was ∼201 °C, while the Tm of the crystalline form was ∼187 °C. Raman spectra supported a more α-helix rich structure of crystalline lysozyme. This structure is consistent with reduced cooperative unit sizes compared to the amorphous lysozyme and is consistent with a reduction in the Tm of the crystalline form. Evidence was obtained that milling also induced denaturation in the solid-state, with the denatured lysozyme showing no thermal transition. The denaturation of the crystalline lysozyme occurred mainly through its amorphous form. Interestingly, the mechanical denaturation of lysozyme did not affect its biological activity on dissolution. Lysozyme crystals on drying did not become amorphous, while milling-time played a crucial role in the crystalline-amorphous-denatured transformations of lysozyme crystals. DSC is shown to be a key tool to monitor quantitatively these transformations.

  18. Microorganisms in Confined Habitats: Microbial Monitoring and Control of Intensive Care Units, Operating Rooms, Cleanrooms and the International Space Station.

    Science.gov (United States)

    Mora, Maximilian; Mahnert, Alexander; Koskinen, Kaisa; Pausan, Manuela R; Oberauner-Wappis, Lisa; Krause, Robert; Perras, Alexandra K; Gorkiewicz, Gregor; Berg, Gabriele; Moissl-Eichinger, Christine

    2016-01-01

    Indoor environments, where people spend most of their time, are characterized by a specific microbial community, the indoor microbiome. Most indoor environments are connected to the natural environment by high ventilation, but some habitats are more confined: intensive care units, operating rooms, cleanrooms and the international space station (ISS) are extraordinary living and working areas for humans, with a limited exchange with the environment. The purposes for confinement are different: a patient has to be protected from infections (intensive care unit, operating room), product quality has to be assured (cleanrooms), or confinement is necessary due to extreme, health-threatening outer conditions, as on the ISS. The ISS represents the most secluded man-made habitat, constantly inhabited by humans since November 2000 - and, inevitably, also by microorganisms. All of these man-made confined habitats need to be microbiologically monitored and controlled, by e.g., microbial cleaning and disinfection. However, these measures apply constant selective pressures, which support microbes with resistance capacities against antibiotics or chemical and physical stresses and thus facilitate the rise of survival specialists and multi-resistant strains. In this article, we summarize the available data on the microbiome of aforementioned confined habitats. By comparing the different operating, maintenance and monitoring procedures as well as microbial communities therein, we emphasize the importance to properly understand the effects of confinement on the microbial diversity, the possible risks represented by some of these microorganisms and by the evolution of (antibiotic) resistances in such environments - and the need to reassess the current hygiene standards.

  19. Microorganisms in confined habitats: Microbial monitoring and control of intensive care units, operating rooms, cleanrooms and the International Space Station

    Directory of Open Access Journals (Sweden)

    Maximilian Mora

    2016-10-01

    Full Text Available Indoor environments, where people spend most of their time, are characterized by a specific microbial community, the indoor microbiome. Most indoor environments are connected to the natural environment by high ventilation, but some habitats are more confined: intensive care units, operating rooms, cleanrooms and the international space station (ISS are extraordinary living and working areas for humans, with a limited exchange with the environment. The purposes for confinement are different: a patient has to be protected from infections (intensive care unit, operating room, product quality has to be assured (cleanrooms, or confinement is necessary due to extreme, health-threatening outer conditions, as on the ISS. The ISS represents the most secluded man-made habitat, constantly inhabited by humans since November 2000 – and, inevitably, also by microorganisms. All of these man-made confined habitats need to be microbiologically monitored and controlled, by e.g. microbial cleaning and disinfection. However, these measures apply constant selective pressures, which support microbes with resistance capacities against antibiotics or chemical and physical stresses and thus facilitate the rise of survival specialists and multi-resistant strains. In this article, we summarize the available data on the microbiome of aforementioned confined habitats. By comparing the different operating, maintenance and monitoring procedures as well as microbial communities therein, we emphasize the importance to properly understand the effects of confinement on the microbial diversity, the possible risks represented by some of these microorganisms and by the evolution of (antibiotic resistances in such environments - and the need to reassess the current hygiene standards.

  20. Effects of chemical protective equipment on team process performance in small unit rescue operations.

    Science.gov (United States)

    Grugle, Nancy L; Kleiner, Brian M

    2007-09-01

    In the event of a nuclear, biological, or chemical terrorist attack against civilians, both military and civilian emergency response teams must be able to respond and operate efficiently while wearing protective equipment. Chemical protective equipment protects the user by providing a barrier between the individual and hazardous environment. Unfortunately, the same equipment that is designed to support the user can potentially cause heat stress, reduced task efficiency, and reduced range-of-motion. Targeted Acceptable Responses to Generated Events of Tasks (TARGETS), an event-based team performance measurement methodology was used to investigate the effects of Mission Oriented Protective Posture (MOPP) on the behavioral processes underlying team performance during simulated rescue tasks. In addition, this study determined which team processes were related to team performance outcomes. Results of six primary analyses indicated that team process performance was not degraded by MOPP 4 on any rescue task and that the team processes critical for successful task performance are task-dependent. This article discusses the implications of these results with respect to the study design and the limitations of using an event-based team performance measurement methodology.

  1. Depot medroxyprogesterone in the management of benign prostatic hyperplasia.

    Science.gov (United States)

    Onu, P E

    1995-01-01

    The effects of depot medroxyprogesterone (DMPA), a 5 alpha-reductase, luteinizing-hormone release and human androgen receptor adhesion inhibitor, were assessed in 80 patients with benign prostatic hyperplasia (BPH) in a double-blind, placebo-controlled study. Patients were randomized to DMPA 150 mg single-dose intramuscular injection or placebo in a similar fashion. The following changes were seen with DMPA after 3 months (duration of DMPA effect): (1) serum testosterone reached castration levels within 3 days as compared to no changes in the placebo group; (2) the prostate volume was reduced by 25% compared to a 3% decrease with placebo (p < 0.001); (3) maximum urinary-flow rates increased by 3.7 ml/s compared to placebo (p < 0.001); (4) total urinary symptom scores decreased by 4.9 points compared to a nonsignificant decrease with placebo (p < 0.005). There was a 2.5-point decrease in irritative symptoms (urinary frequency, nocturia and urgency) as compared to a nonsignificant decrease with placebo (p < 0.005). After 3 months, the urinary symptoms and urodynamic changes were reversed but significantly greater than the baseline values (p < 0.001). The prostates showed regrowth to the initial sizes within 18-36 weeks. DMPA was better tolerated, except for a higher incidence of impotence, decreased libido and ejaculatory disorders, than in the placebo group. The quality of life is improved with DMPA since it did not produce hot flashes. It was concluded that single-dose DMPA 150 mg is a safe and effective treatment for prostatic obstruction where potency is a secondary consideration.

  2. Bone density in women receiving depot medroxyprogesterone acetate for contraception.

    Science.gov (United States)

    Cundy, T; Evans, M; Roberts, H; Wattie, D; Ames, R; Reid, I R

    1991-01-01

    OBJECTIVE--To determine if the use of the injectable contraceptive depot medroxyprogesterone (DMPA), which reduces ovarian oestrogen production, is associated with changes in bone density. DESIGN--Population study. DMPA users were compared with two control groups selected from larger population studies and individually matched for several putative determinants of bone density (age, race, body mass index, and years of oestrogen deficiency). Controls and DMPA users were matched without prior knowledge of their bone density measurements. SETTING--Teaching hospital and community family planning clinics. SUBJECTS--30 current users of DMPA with a minimum five years' previous use, 30 premenopausal controls, and 30 postmenopausal controls. MAIN OUTCOME MEASURE--Lumbar spine and femoral neck bone mineral density assessed by dual energy x ray absorptiometry. RESULTS--Compared with premenopausal controls matched for age, race, and body mass index, DMPA users had significantly reduced bone density in the lumbar spine (mean difference 7.5% (95% confidence interval 1.9% to 13.1%), p = 0.002) and in the femoral neck (6.6%, (0.8% to 12.3%), p = 0.007). Compared with postmenopausal controls matched for body mass index and duration of oestrogen deficiency, DMPA users had greater bone density in the lumbar spine (8.9% (4.3% to 13.5%), p = 0.001), but in the femoral neck the difference in bone density was less (4.0% (-0.4% to 8.5%), p = 0.04). CONCLUSIONS--Women using DMPA have bone density values intermediate between those of normal premenopausal and postmenopausal controls; thus, the degree of oestrogen deficiency induced by DMPA may have an adverse effect on bone density. PMID:1830502

  3. Disposal of chemical agents and munitions stored at Umatilla Depot Activity, Hermiston, Oregon. Final Phase 1 environmental report

    Energy Technology Data Exchange (ETDEWEB)

    Zimmerman, G.P.; Hillsman, E.L.; Johnson, R.O.; Miller, R.L.; Patton, T.G.; Schoepfle, G.M.; Tolbert, V.R.; Feldman, D.L.; Hunsaker, D.B. Jr.; Kroodsma, R.L.; Morrissey, J.; Rickert, L.W.; Staub, W.P.; West, D.C.

    1993-02-01

    The Umatilla Depot Activity (UMDA) near Hermiston, Oregon, is one of eight US Army installations in the continental United States where lethal unitary chemical agents and munitions are stored, and where destruction of agents and munitions is proposed under the Chemical Stockpile Disposal Program (CSDP). The chemical agent inventory at UMDA consists of 11.6%, by weight, of the total US stockpile. The destruction of the stockpile is necessary to eliminate the risk to the public from continued storage and to dispose of obsolete and leaking munitions. In 1988 the US Army issued a Final Programmatic Environmental Impact Statement (FPEIS) for the CSDP that identified on-site disposal of agents and munitions as the environmentally preferred alternative (i.e., the alternative with the least potential to cause significant adverse impacts), using a method based on five measures of risk for potential human health and ecosystem/environmental effects; the effectiveness and adequacy of emergency preparedness capabilities also played a key role in the FPEIS selection methodology. In some instances, the FPEIS included generic data and assumptions that were developed to allow a consistent comparison of potential impacts among programmatic alternatives and did not include detailed conditions at each of the eight installations. The purpose of this Phase 1 report is to examine the proposed implementation of on-site disposal at UMDA in light of more recent and more detailed data than those included in the FPEIS. Specifically, this Phase 1 report is intended to either confirm or reject the validity of on-site disposal for the UMDA stockpile. Using the same computation methods as in the FPEIS, new population data were used to compute potential fatalities from hypothetical disposal accidents. Results indicate that onsite disposal is clearly preferable to either continued storage at UMDA or transportation of the UMDA stockpile to another depot for disposal.

  4. Chemical Stockpile Disposal Program: Review and comment on the Phase 1 environmental report for the Pueblo Depot Activity, Pueblo, Colorado

    Energy Technology Data Exchange (ETDEWEB)

    Olshansky, S.J.; Krummel, J.R.; Policastro, A.J.; McGinnis, L.D.

    1994-03-01

    As part of the Chemical Stockpile Disposal Program, an independent review is presented of the US Army Phase I environmental report for the disposal of chemical agents and munitions stored at the Pueblo Depot Activity (PUDA) in Pueblo, Colorado. The Phase I report addresses new and additional concerns not incorporated in the final programmatic environmental impact statement (FPEIS). These concerns are addressed by examining site-specific data for the PUDA. On the basis of our review of the Phase I report, we concluded that on-site meteorological data from December 1988 to June 1992 appear to be of insufficient quality to have been used instead of the off-site Pueblo airport data. No additional meteorological data have been collected since June 1992. The Phase I report briefly mentions problems with the air pollution control system. These problems will likely require the systems to be upgraded at the Johnston Atoll site and at each of the other depots in the continental United States. Without such improvements, the probability of accidents during start-up and shutdown would likely increase. The Army has a lessons-learned program to incorporate improvements into the design of future facilities. The Phase I report does not make any design change commitments. These issues need to be fully evaluated and resolved before any final conclusion concerning the adequacy of the decision in the FPEIS can be made with respect to the PUDA. With the exception of this issue, the inclusion of other more detailed site-specific data in the Phase I report does not change the decision reached in the FPEIS (which favored on-site disposal at the PUDA). We recommend that site-specific data on water, ecological, socioeconomic, and cultural resources and emergency planning and preparedness be considered explicitly in the site-specific EIS decision-making process.

  5. Artificial intelligence technology assessment for the US Army Depot System Command

    Energy Technology Data Exchange (ETDEWEB)

    Pennock, K A

    1991-07-01

    This assessment of artificial intelligence (AI) has been prepared for the US Army's Depot System Command (DESCOM) by Pacific Northwest Laboratory. The report describes several of the more promising AI technologies, focusing primarily on knowledge-based systems because they have been more successful in commercial applications than any other AI technique. The report also identifies potential Depot applications in the areas of procedural support, scheduling and planning, automated inspection, training, diagnostics, and robotic systems. One of the principal objectives of the report is to help decisionmakers within DESCOM to evaluate AI as a possible tool for solving individual depot problems. The report identifies a number of factors that should be considered in such evaluations. 22 refs.

  6. Multi-depot Vehicle Routing Problem with Pickup and Delivery Requests

    Science.gov (United States)

    Sombuntham, Pandhapon; Kachitvichyanukul, Voratas

    2010-10-01

    This paper considers a multi-depot vehicle routing problem with pickup and delivery requests. In the problem of interest, each location may have goods for both pickup and delivery with multiple delivery locations that may not be the depots. These characteristics are quite common in industrial practice. A particle swarm optimization algorithm with multiple social learning structures is proposed for solving the practical case of multi-depot vehicle routing problem with simultaneous pickup and delivery and time window. A new decoding procedure is implemented using the PSO class provided in the ETLib object library. Computational experiments are carried out using the test instances for the pickup and delivery problem with time windows (PDPTW) as well as a newly generated instance. The preliminary results show that the proposed algorithm is able to provide good solutions to most of the test problems.

  7. A 3/2-Approximation Algorithm for Multiple Depot Multiple Traveling Salesman Problem

    Science.gov (United States)

    Xu, Zhou; Rodrigues, Brian

    As an important extension of the classical traveling salesman problem (TSP), the multiple depot multiple traveling salesman problem (MDMTSP) is to minimize the total length of a collection of tours for multiple vehicles to serve all the customers, where each vehicle must start or stay at its distinct depot. Due to the gap between the existing best approximation ratios for the TSP and for the MDMTSP in literature, which are 3/2 and 2, respectively, it is an open question whether or not a 3/2-approximation algorithm exists for the MDMTSP. We have partially addressed this question by developing a 3/2-approximation algorithm, which runs in polynomial time when the number of depots is a constant.

  8. Introduction of an acute surgical unit: comparison of performance indicators and outcomes for operative management of acute appendicitis.

    Science.gov (United States)

    Lancashire, John F; Steele, M; Parker, D; Puhalla, H

    2014-08-01

    The Acute Surgical Unit (ASU) is a recent change in management of acute general surgical patients in hospitals worldwide. In contrast to traditional management of acute surgical presentations by a rotating on-call system, ASUs are shown to deliver improved efficiency and patient outcomes. This study investigated the impact of an ASU on operative management of appendicitis, the most common acute surgical presentation, by comparing performance indicators and patient outcomes prior to and after introduction of an ASU at the Gold Coast Hospital, Queensland, Australia. A retrospective study of patients admitted from the Emergency Department (ED) and who underwent emergency appendectomy from February 2010 to January 2011 (pre-ASU) and after introduction of the ASU from February 2011 to January 2012 (post-ASU). A total of 548 patients underwent appendectomy between February 2010 and January 2012, comprising 247 pre-ASU and 301 post-ASU patients. Significant improvements were demonstrated: reduced time to surgical review, fewer complications arising from operations commencing during ASU in-hours, and more appendectomies performed during the daytime attended by the consultant. There was no significant difference in total cost of admission or total admission length of stay. This study demonstrated that ASUs have potential to significantly improve the outcomes for operative management of acute appendicitis compared to the traditional on-call model. The impact of the ASU was limited by access to theaters and restricted ASU operation hours. Further investigation of site-specific determinants could be beneficial to optimize this new model of acute surgical care.

  9. Deployment and operation of a transportable burn intensive care unit in response to a burn multiple casualty incident.

    Science.gov (United States)

    Barillo, David J; Cancio, Leopoldo C; Stack, Richard S; Carr, Shamus R; Broger, Kristine P; Crews, David M; Renz, Evan M; Blackbourne, Lorne H

    2010-01-01

    In many hospitals, intensive care units (ICUs) operate at or above capacity on a daily basis. Multiple casualty incidents will create a sudden need for additional ICU beds and hospital planning for disaster response must anticipate the need for rapid ICU expansion. In this article, the authors describe the management of 6 patients who were burned in Guam and successfully transported a distance of 7,268 miles to San Antonio, TX, for tertiary burn center care. The mission required creation of a temporary burn ICU at Tripler Army Medical Center in Hawaii, approximately midway between the referring hospital and the receiving burn center. A method of creating a temporary burn center is described. Lessons learned, including the need to standardize equipment, and to cross-train and cross-credential medical personnel, are applicable to both military and civilian mass casualty management.

  10. LITERATURE SURVEY FOR GROUNDWATER TREATMENT OPTIONS FOR NITRATE IODINE-129 AND URANIUM 200-ZP-1 OPERABLE UNIT HANFORD SITE

    Energy Technology Data Exchange (ETDEWEB)

    BYRNES ME

    2008-06-05

    This literature review presents treatment options for nitrate, iodine-129, and uranium, which are present in groundwater at the 200-ZP-I Groundwater Operable Unit (OU) within the 200 West Area of the Hanford Site. The objective of this review is to determine available methods to treat or sequester these contaminants in place (i.e., in situ) or to pump-and-treat the groundwater aboveground (i.e., ex situ). This review has been conducted with emphasis on commercially available or field-tested technologies, but theoretical studies have, in some cases, been considered when no published field data exist. The initial scope of this literature review included only nitrate and iodine-I 29, but it was later expanded to include uranium. The focus of the literature review was weighted toward researching methods for treatment of nitrate and iodine-129 over uranium because of the relatively greater impact of those compounds identified at the 200-ZP-I OU.

  11. Final Hazard Categorization for the Remediation of Six 300-FF-2 Operable Unit Solid Waste Burial Grounds

    Energy Technology Data Exchange (ETDEWEB)

    J. D. Ludowise

    2006-12-12

    This report provides the final hazard categorization (FHC) for the remediation of six solid waste disposal sites (referred to as burial grounds) located in the 300-FF-2 Operable Unit (OU) on the Hanford Site. These six sites (618-1, 618-2, 618-3, 618-7, 618-8, and 618-13 Burial Grounds) were determined to have a total radionuclide inventory (WCH 2005a, WCH 2005d, WCH 2005e and WCH 2006b) that exceeds the DOE-STD-1027 Category 3 threshold quantity (DOE 1997) and are the subject of this analysis. This FHC document examines the hazards, identifies appropriate controls to manage the hazards, and documents the FHC and commitments for the 300-FF-2 Burial Grounds Remediation Project.

  12. A control approach for the operation of DG units under variations of interfacing impedance in grid-connected mode

    DEFF Research Database (Denmark)

    Hoseini, S. Kazem; Pouresmaeil, E.; Hosseinnia, S. H.

    2016-01-01

    converter is highly sensitive to the impacts of this impedance changes; then, DG unit cannot inject appropriate currents. To deal with the instability problem, a control method based on fractional order active sliding mode is proposed in this paper, which is less sensitive to variations of interfacing...... impedance. A fractional sliding surface, which demonstrates the desired dynamics of system is developed and then, the controller is designed in two phases as sliding and reaching phases to keep the control loop stable. Stability issues of the control method are discussed in details and the conditions...... in which the proposed model works in a stable operating mode is defined. The proposed control method takes a role to provide high quality power injection and ensures precise references tracking and fast response despite such uncertainties. Theoretical analyses and simulation results are established...

  13. Field Sampling Plan for the Operable Units 6-05 and 10-04 Remedial Action, Phase IV

    Energy Technology Data Exchange (ETDEWEB)

    R. Wells

    2006-11-14

    This Field Sampling Plan outlines the collection and analysis of samples in support of Phase IV of the Waste Area Group 10, Operable Units 6-05 and 10-04 remedial action. Phase IV addresses the remedial actions to areas with the potential for unexploded ordnance at the Idaho National Laboratory Site. These areas include portions of the Naval Proving Ground, the Arco High-Altitude Bombing Range, and the Twin Buttes Bombing Range. The remedial action consists of removal and disposal of ordnance by high-order detonation, followed by sampling to determine the extent, if any, of soil that might have been contaminated by the detonation activities associated with the disposal of ordnance during the Phase IV activities and explosives during the Phase II activities.

  14. Limited Field Investigation Report for Uranium Contamination in the 300 Area, 300-FF-5 Operable Unit, Hanford Site, Washington

    Energy Technology Data Exchange (ETDEWEB)

    Williams, Bruce A.; Brown, Christopher F.; Um, Wooyong; Nimmons, Michael J.; Peterson, Robert E.; Bjornstad, Bruce N.; Lanigan, David C.; Serne, R. Jeffrey; Spane, Frank A.; Rockhold, Mark L.

    2007-11-01

    Four new CERCLA groundwater monitoring wells were installed in the 300-FF-5 Operable Unit in FY 2006 to fulfill commitments for well installations proposed in the Hanford Federal Facility Agreement and Consent Order Milestone M-24-57. Wells were installed to collect data to determine the distribution of process uranium and other contaminants of potential concern in groundwater. These data will also support uranium contaminant transport simulations and the wells will supplement the water quality monitoring network for the 300-FF-5 OU. This report supplies the information obtained during drilling, characterization, and installation of the new groundwater monitoring wells. This document also provides a compilation of hydrogeologic, geochemical, and well construction information obtained during drilling, well development, and sample collection/analysis activities.

  15. Evaluation and Screening of Remedial Technologies for Uranium at the 300-FF-5 Operable Unit, Hanford Site, Washington

    Energy Technology Data Exchange (ETDEWEB)

    Nimmons, Michael J.

    2007-08-01

    Pacific Northwest National Laboratory (PNNL) is presently conducting a re-evaluation of remedies addressing persistent dissolved uranium concentrations in the upper aquifer under the 300 Area of the Hanford Site in southeastern Washington State. This work is being conducted as a Phase III feasibility study for the 300-FF-5 Operable Unit on behalf of the U.S. Department of Energy. As part of the feasibility study process, a comprehensive inventory of candidate remedial technologies was conducted by PNNL. This report documents the identification and screening of candidate technologies. The screening evaluation was conducted in accordance with guidance and processes specified by U.S. Environmental Protection Agency regulations associated with implementation of the Comprehensive Environmental Response, Compensation, and Liability Act process.

  16. [The implementation of an independent and differentiated pain management SOP (Standard Operating Procedure) for the interdisciplinary intensive care unit].

    Science.gov (United States)

    Aust, Hansjörg; Wulf, Hinnerk; Vassiliou, Timon

    2013-03-01

    Up to the present day, pain management in the ICU (Intensive Care Units) is a unresolved clinical problem due to patient heterogeneity with complex variation in etiopathology and treatment of the underlying diseases. Therefore, therapeutic strategies in terms of standard operating procedure (SOP) are a necessary to improve the pain management for intensive care patients. Common guidelines for analgosedation are often inadequate to reflect the clinical situation. In particular, for an ICU setting without permanent presence of a physician a missing pain management SOP resulting in delayed pain therapy caused by a therapeutic uncertainty of the nurse staff. In addition to our pre-existing SOP for analgosedation we implemented a pain management SOP for our interdisciplinary, anaesthesiologic ICU. A exploratory survey among the nurse staff was conducted to assess the efficacy of the SOP. The results of the evaluation after a 6 month follow-up indicated a faster onset of pain management and good acceptance by the nursing staff.

  17. Assassination in the United States: an operational study of recent assassins, attackers, and near-lethal approachers.

    Science.gov (United States)

    Fein, R A; Vossekuil, B

    1999-03-01

    This study is the first operational exploration of the thinking and behavior of all 83 persons known to have attacked, or approached to attack, a prominent public official or public figure in the United States since 1949. In addition to data about each attack or near-attack and each subject's demographic and background characteristics, information was gathered about each subject's ideas and actions in the days and weeks before their attacks or near-lethal approaches. Questions were examined about each subject's movement from the idea of attack to actual attack, motives, selection of targets, planning, communication of threat and intent, symptoms of mental illness, and significant life experiences. In every case, the attack or near-attack was the end result of an understandable, and often discernible, process of thinking and action. Implications for protectors, investigators, and researchers are discussed.

  18. Planning intensive care unit design using computer simulation modeling: optimizing integration of clinical, operational, and architectural requirements.

    Science.gov (United States)

    OʼHara, Susan

    2014-01-01

    Nurses have increasingly been regarded as critical members of the planning team as architects recognize their knowledge and value. But the nurses' role as knowledge experts can be expanded to leading efforts to integrate the clinical, operational, and architectural expertise through simulation modeling. Simulation modeling allows for the optimal merge of multifactorial data to understand the current state of the intensive care unit and predict future states. Nurses can champion the simulation modeling process and reap the benefits of a cost-effective way to test new designs, processes, staffing models, and future programming trends prior to implementation. Simulation modeling is an evidence-based planning approach, a standard, for integrating the sciences with real client data, to offer solutions for improving patient care.

  19. Are depot as effective as oral antipsychotics on first-episode psychosis?

    Science.gov (United States)

    Orus, Cristián; Aceituno, David

    2016-05-23

    Depot antipsychotics have been generally used in patients with chronic schizophrenia with adherence problems to oral therapy. However, it has been suggested they can be a good alternative in earlier stages too. Searching in Epistemonikos database, which is maintained by screening 30 databases, we identified three systematic reviews including two pertinent randomized trials. We combined the evidence using meta-analysis and generated a summary of findings table following the GRADE approach. We concluded it is not clear whether there are differences between depot and oral antipsychotics in first-episode psychosis because the certainty of the available evidence is very low.

  20. Operational Use of the US Army Reserve in Foreign Disaster Relief to Support the United States Government’s Strategic Use of Humanitarian Assistance and Disaster Response

    Science.gov (United States)

    2015-05-21

    in military operations over the last two decades are foundational for the USAR’s institutional agility and flexibility. Reservists are also...Assistance and Disaster Response A Monograph by MAJ Kelly J. Pajak United States Army Reserve School of Advanced Military ...PERFORMING ORG REPORT NUMBER 9. SPONSORING / MONITORING AGENCY NAME(S) AND ADDRESS(ES) Advanced Operational Arts Studies Fellowship, Advanced Military

  1. 地铁车辆段/停车场列车运营日计划优化模型与算法研究%Optimization model and algorithm of train operation daily plan for metro depot/parking lot

    Institute of Scientific and Technical Information of China (English)

    牟宗元; 马亮

    2016-01-01

    Considering the requirements of train operation in the main line, maintenance and shunting, the optimization problem for train operation daily plan could be boiled down to an assignment problem, and then the 0-1 integer programming model was established. Because the objective function of the optimization model is uncertain, and in order to improve the solution efifciency, a heuristic algorithm based on the priority principles was designed according to the practical experience and the priority principles of planning. Because of the objective function is uncertain and in order to improve the solution efifciency, a heuristic algorithm based on the priority principles was designed according to the practical experience and the priority principles of planning. Meanwhile the train operation daily plans were drawn up automatically by using computer aided decision-making. The effectiveness of the model and algorithm was veriifed by an example.%综合考虑列车正线运营、车辆检修、车辆调车等需求,将列车运营日计划优化问题归结为指派问题,并建立0-1整数规划模型。针对优化模型的目标函数不确定性及为了提高求解效率,根据实际经验和计划编制优先原则,设计一种基于规则的启发式算法,并利用计算机辅助决策实现运营日计划的自动编制。通过实例验证了模型和算法的有效性。

  2. Feasibility study for remedial action for the Quarry Residuals Operable Unit at the Weldon Spring Site, Weldon Spring, Missouri

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    The U.S. Department of Energy (DOE) is conducting cleanup activities at the Weldon Spring site, which is located in St. Charles County, Missouri, about 48 km (30 mi) west of St. Louis (Figure 1.1). Cleanup of the Weldon Spring site consists of several integrated components. The quarry residuals operable unit (QROU) is one of four operable units being evaluated. In accordance with the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), as amended, a remedial investigation/feasibility study (RI/FS) is being conducted to evaluate conditions and potential responses for the following areas and/or media that constitute the QROU: (1) the residual material (soil and sediment) remaining at the Weldon Spring quarry after removal of the bulk waste (about 11 million L [3 million gal] of uranium-contaminated ponded water was also addressed previous to bulk waste removal); (2) other media located in the surrounding vicinity of the quarry, including adjacent soil, surface water, and sediment in Femme Osage Slough and several creeks; and (3) quarry groundwater located primarily north of Femme Osage Slough. Potential impacts to the St. Charles County well field downgradient of the quarry area are also being addressed as part of QROU RI/FS evaluations. For remedial action sites, it is DOE policy to integrate values associated with the National Environmental Policy Act (NEPA) into the CERCLA decision-making process. The analyses contained herein address NEPA values as appropriate to the actions being considered for the QROU. A work plan summarizing initial site conditions and providing conceptual site hydrogeological and exposure models was published in January 1994. The RI and baseline risk assessment (BRA) reports have been completed. The RI discusses in detail the nature and extent and the fate and transport of contamination at the quarry area.

  3. New Pump and Treat Facility Remedial Action Work Plan For Test Area North Final Groundwater Remediation, Operable Unit 1-07B

    Energy Technology Data Exchange (ETDEWEB)

    Nelson, L. O.

    2007-06-12

    This remedial action work plan identifies the approach and requirements for implementing the medial zone remedial action for Test Area North, Operable Unit 1-07B, at the Idaho National Laboratory. This plan details the management approach for the construction and operation of the New Pump and Treat Facility (NPTF). As identified in the remediatial design/remedial action scope of work, a separate remedial design/remedial action work plan will be prepared for each remedial component of the Operable Unit 1-07B remedial action.

  4. Depo-Provera (depot medroxyprogesterone acetate use after bariatric surgery

    Directory of Open Access Journals (Sweden)

    Lam C

    2016-09-01

    Full Text Available Clarissa Lam,1 Amitasrigowri S Murthy2,3 1New York University School of Medicine, 2Department of Obstetrics and Gynecology, Bellevue Hospital Center, New York University School of Medicine, 3New York University Langone Medical Center, New York, NY, USA Abstract: In the US, obesity rates are increasing greatly. The Centers for Disease Control and Prevention estimates that 68.5% of Americans, including 63.9% of adult women older than 20 years, are overweight (body mass index between 25 kg/m2 and 29.9 kg/m2 or obese (body mass index >30 kg/m2. In light of this, it is not surprising that the rates of bariatric surgery have also been increasing. When considering the metabolic changes associated with both bariatric surgery and contraceptive use, in combination with the unique medical considerations of obese women, it is indisputable that clear guidelines are needed when counseling obese patients of reproductive age after bariatric surgery. In this literature review, we focus on depot medroxyprogesterone acetate (DMPA and the implications of its use in obese women, preweight and postweight loss following bariatric surgery. Both DMPA use and bariatric surgery are known to cause bone loss, but it is still unclear whether there is an additive effect of the two factors on bone loss and whether either of these factors directly leads to an increased risk of bone fracture. The current consensus guidelines do not impose a restriction on the use of DMPA after bariatric surgery. DMPA use is associated with weight gain, and it is unclear whether weight loss blunting occurs with the use of DMPA after bariatric surgery. Prior studies had demonstrated an association with weight gain in adolescents, and therefore, those prescribing DMPA use after bariatric surgery in adolescents should proceed with caution. Adult women do not have a similar response to the use of DMPA. DMPA use has rarely been associated with increased risk of venous thromboembolism (VTE. The

  5. Clinical outcome of one-third-dose depot triptorelin is the same as half-dose depot triptorelin in the long protocol of controlled ovarian stimulation

    Directory of Open Access Journals (Sweden)

    Yu Li

    2012-01-01

    Full Text Available Objective: Appropriate dosage of the long-acting depot gonadotrophin releasing hormone (GnRH agonist has not been determined in long protocol for IVF, and one-third-dose depot triptorelin was compared with half-dose in a luteal long protocol of in-vitro fertilization/ intra cytoplasmic sperm injection (IVF/ICSI treatment in this study. Materials and Methods: This is a prospective, randomized, open clinical trial. 100 patients were randomized into two groups. Group I received one-third-dose (1.25 mg depot triptorelin. Group II received half-dose (1.87 mg. The clinical and experimental parameters were compared between the two groups. Results: There was no premature luteinizing hormone (LH surge in both groups. On Day 3-5 of menstrual cycle after down-regulation, fewer patients showed low-level LH (<1.0 IU/L and estradiol (<30 pg/mL in group I (P <0.05. There were fewer oocytes retrieved (P =0.086, fewer total embryos and available embryos for cryopreservation in Group I (P <0.05, while good-quality embryo rate was higher in group I (P <0.05. The length and dose of ovarian stimulation was lower in Group I, but not significantly. The clinical pregnancy (52% versus 40%, implantation (48% versus 37.5%, delivery (46% versus 32%, or live birth (42% versus 32% rates and the abortion (8% versus 20% rates showed no significant differences. Conclusion: Depot triptorelin 1.25 mg can be successfully used with reduced pituitary suppression and lower cost in a long protocol for in-vitro fertilization.

  6. The modelling of dynamic chemical state of paper machine unit operations; Dynaamisen kemiallisen tilan mallintaminen paperikoneen yksikkoeoperaatioissa - MPKT 04

    Energy Technology Data Exchange (ETDEWEB)

    Ylen, J.P.; Jutila, P. [Helsinki Univ. of Technology, Otaniemi (Finland)

    1998-12-31

    The chemical state of paper mass is considered to be a key factor to the smooth operation of the paper machine. There are simulators that have been developed either for dynamic energy and mass balances or for static chemical phenomena, but the combination of these is not a straight forward task. Control Engineering Laboratory of Helsinki University of Technology has studied the paper machine wet end phenomena with the emphasis on pH-modelling. VTT (Technical Research Centre of Finland) Process Physics has used thermodynamical modelling successfully in e.g. Bleaching processes. In this research the different approaches are combined in order to get reliable dynamical models and modelling procedures for various unit operations. A flexible pilot process will be constructed and different materials will be processed starting from simple inorganic substances (e.g. Calcium carbonate and distilled water) working towards more complex masses (thick pulp with process waters and various reagents). The pilot process is well instrumented with ion selective electrodes, total calcium analysator and all basic measurements. (orig.)

  7. Remedial investigation/feasibility study of the Clinch River/Poplar Creek operable unit. Volume 1: Main text

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-06-01

    This report presents the findings of an investigation into contamination of the Clinch River and Poplar Creek near the US Department of Energy`s (DOE`s) Oak Ridge Reservation (ORR) in eastern Tennessee. For more than 50 years, various hazardous and radioactive substances have been released to the environment as a result of operations and waste management activities at the ORR. In 1989, the ORR was placed on the National Priorities List (NPL), established and maintained under the federal Comprehensive environmental Response, Compensation, and Liability Act of 1980 (CERCLA). Under CERCLA, NPL sites must be investigated to determine the nature and extent of contamination at the site, assess the risk to human health and the environment posed by the site, and, if necessary, identify feasible remedial alternatives that could be used to clean the site and reduce risk. To facilitate the overall environmental restoration effort at the ORR, CERCLA activities are being implemented individually as distinct operable units (OUs). This document is the combined Remedial Investigation and Feasibility Study Report for the Clinch River/Poplar Creek OU.

  8. [Decision on the time for post-operative extubation of maxillofacial surgery patient in the intensive care unit].

    Science.gov (United States)

    Curiel Balsera, E; Prieto Palomino, M A; Muñoz Bono, J; Arias Verdú, M D; Mora Ordóñez, J; Quesada García, G

    2009-03-01

    Evaluate moment of extubation in maxillofacial post-operative patients admitted to an intensive care unit (ICU) and analyze early complications during their stay. An observational and prospective study. Third level hospital ICU. All patients we underwent maxillofacial surgery and admitted to the ICU for immediate post-operative care from February 2007 to March 2008 were studied. Demographic and clinical data variables of the patients, anesthesic variables prior to surgery and mechanical ventilation and postoperative complications during their stay in the ICU were recorded. A total of 102 patients were collected during the study. Of these, 58 (55.8%) patients were extubated early (within the first 4 hours of admission). Global rate of complications was 12.5%. Length of mechanical ventilation was longer in patients who required cervical lymph node extraction (p = 0.0031). We found an association between complications and late extubation (p = 0.034; OR = 3.78; 95% CI, 1.16-12.31). The multivariant study showed that late extubation and surgery that required lymph node extraction are predictors of complications. In our series, late extubation and the need for cervical lymph node extraction were independent risk factors for complications in ICU. Although early extubation may be hazardous in some cases in the first hours, we have no consistent data to maintain mechanical ventilation longer than needed to recover from the anesthesia.

  9. Ten years maintaining MACAO-VLTI units in operation in the Very Large Telescope at Paranal Observatory

    Science.gov (United States)

    Salgado, F.; Hudepohl, G.

    2016-07-01

    More than 10 years have already passed since the first Multiple Application Curvature Adaptive Optics (MACAO) facilities got the first light in UT2 the 18th of April, 2003, in the Very Large Telescope (VLT) at Paranal Observatory. The achievable image sharpness of a ground-based telescope is normally limited by the effect of atmospheric turbulence. However, with Adaptive Optics (AO) techniques, this major drawback can be overcome so that the telescope produces images that are as sharp as theoretically possible, i.e., as if they were taken from space. [1] The intention of this document is summarize in few pages some highlights related with the activities needed to keep MACAO units in operation. Some statistics of problems based in Action Remedy tool is included, showing how through these years the number of problems has been reduced, even when there are still some unsolved ones. Some lessons have been learned and there are others one to learn. Corrective and predictive maintenance performed are shown too like the current measurements, transfer functions measurements, thermography pictures, health checks measuring interaction matrix and flat vectors to detect dead APDs or short circuits in the DM, etc. Some forced interventions are included as well like the removal of the cabinets from Coude rooms to avoid that acoustic noise and vibrations perturb the operations, the deformable mirrors reached by cooling leaks and a mirror that got rusty are shown too. Well knowledge of the system, good interaction between different disciplines groups to perform corrective and preventive maintenance seems to be key aspects of keeping it under control and operative during all these years leading to this good result.

  10. Analysis of Acceleration, Airspeed, and Gust-Velocity Data From a Four-Engine Transport Airplane Operating Over a Northwestern United States Alaska Route

    Science.gov (United States)

    Engel, Jerome N.; Copp, Martin R.

    1959-01-01

    Acceleration, airspeed, and altitude data obtained with an NACA VGH recorder from a four-engine commercial transport airplane operating over a northwestern United States-Alaska route were evaluated to determine the magnitude and frequency of occurrence of gust and maneuver accelerations., operating airspeeds, and gust velocities. The results obtained were then compared with the results previously reported in NACA Technical Note 3475 for two similar airplanes operating over transcontinental routes in the United States. No large variations in the gust experience for the three operations were noted. The results indicate that the gust-load experience of the present operation closely approximated that of the central transcontinental route in the United States with which it is compared and showed differences of about 4 to 1 when compared with that of the southern transcontinental route in the United States. In general, accelerations due to gusts occurred much more frequently than those due to operational maneuvers. At a measured normal-acceleration increment of 0.5g, accelerations due to gusts occurred roughly 35 times more frequently than those due to operational maneuvers.

  11. Operational Strategies for Single-Stage Crossdocks

    OpenAIRE

    Wang, Jiana-Fu

    2010-01-01

    Because of the growing importance of hub-and-spoke operations in the trucking industry, crossdocking has become an important and effective tool to transfer freight. Companies like Wal-Mart, Costco and Home Depot are using this kind of facility in their logistics operations. In these crossdocks, efficiently operating them, thereby reducing unnecessary waiting and staging congestion for freight and workers is an important issue for managers. This dissertation uses real-time information...

  12. An Analysis of the Twenty-Nine Capabilities of the Marine Corps Expeditionary Unit (Special Operations Capable)

    Science.gov (United States)

    2007-11-02

    Hostage Recovery ITG Initial Terminal Guidance JEO JTF Enabling Operations JTF Join Task Force JTT Joint/Combined Training/Instruction Team LAR Light...Limited Expeditionary Airfield Operations (EAO). 27. Show of Force Operations (SOFO). 28. JTF Enabling Operations ( JEO ). 29. Sniping Operations (SNO...Relief (HA/DR) Military Operations in Urban Terrain (MOUT) Airfield/Port Seizure (APS) Show of Force Operations (SOFO) JTF Enabling Operations ( JEO

  13. Vessel Operating Units (Vessels)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains data for vessels that are greater than five net tons and have a current US Coast Guard documentation number. Beginning in1979, the NMFS...

  14. Nanosized sustained-release drug depots fabricated using modified tri-axial electrospinning.

    Science.gov (United States)

    Yang, Guang-Zhi; Li, Jiao-Jiao; Yu, Deng-Guang; He, Mei-Feng; Yang, Jun-He; Williams, Gareth R

    2017-01-27

    Nanoscale drug depots, comprising a drug reservoir surrounded by a carrier membrane, are much sought after in contemporary pharmaceutical research. Using cellulose acetate (CA) as a filament-forming polymeric matrix and ferulic acid (FA) as a model drug, nanoscale drug depots in the form of core-shell fibers were designed and fabricated using a modified tri-axial electrospinning process. This employed a solvent mixture as the outer working fluid, as a result of which a robust and continuous preparation process could be achieved. The fiber-based depots had a linear morphology, smooth surfaces, and an average diameter of 0.62±0.07μm. Electron microscopy data showed them to have clear core-shell structures, with the FA encapsulated inside a CA shell. X-ray diffraction and IR spectroscopy results verified that FA was present in the crystalline physical form. In vitro dissolution tests revealed that the fibers were able to provide close to zero-order release over 36h, with no initial burst release and minimal tailing-off. The release properties of the depot systems were much improved over monolithic CA/FA fibers, which exhibited a significant burst release and also considerable tailing-off at the end of the release experiment. Here we thus demonstrate the concept of using modified tri-axial electrospinning to design and develop new types of heterogeneous nanoscale biomaterials.

  15. A framework for measuring efficiency levels :The case of express depots

    NARCIS (Netherlands)

    Banaszewska, A.; Cruijssen, F.C.A.M.; Dullaert, W.; Lemmen-Gerdessen, van J.C.

    2012-01-01

    The efficiency and effectiveness in any distribution network is largely determined by the performance of depots in such a network. The purpose of this study is to develop a methodological framework to evaluate the performance of distribution centers of express companies. The framework is based on Da

  16. Pharmacodynamic effects of depot-medroxyprogesterone acetate (DMPA) administered to lactating women on their male infants

    NARCIS (Netherlands)

    Virutamasen, P; Leepipatpaiboon, S; Kriengsinyot, R; Vichaidith, P; Muia, PN; SekaddeKigondu, CB; Mati, JKG; Forest, MG; Dikkeschei, LD; Wolthers, BG; dArcangues, C

    Normal postpartum women, who had a spontaneous vaginal delivery of one full-term male infant, free of congenital abnormalities and other diseases, were recruited for this study. Thirteen women received 150 mg depot-medroxyprogesterone acetate (DMPA), intramuscularly on days 42 + 1 and 126 + 1

  17. Terbutaline depot tablets in childhood asthma. A double-blind controlled study

    DEFF Research Database (Denmark)

    Foged, N; Høst, A; Ljungholm, K

    1985-01-01

    . The design of the study was double-blind, cross-over, with a randomized allocation of the drugs. Both drugs improved the lung function significantly. The children had significantly less coughing during the night when they took depot tablets than when they took ordinary tablets. The side effects were few...

  18. Depot-specific differences in perilipin and hormone-sensitive lipase expression in lean and obese

    Directory of Open Access Journals (Sweden)

    Beylot Michel

    2009-12-01

    Full Text Available Abstract Background Mainly dependent on hormone-sensitive lipase, lipolysis is differently impaired between fat depots in human obesity. Perilipin A expression is a critical element in adipocyte lipolysis. The present study aimed at comparing expression and subcellular distribution of perilipin and hormone-sensitive lipase in two abdominal adipose tissues of lean and obese women. We examined whether regional differences in perilipin expression contribute to impaired lipolytic rates. Methods Abdominal subcutaneous and omental adipose tissues were obtained from six lean and ten obese women. We measured total protein content and relative distribution of hormone-sensitive lipase and perilipin proteins between lipid and non-lipid fractions in tissue homogenates. Hormone-sensitive lipase and perilipin mRNA levels, adipocyte size, basal (non-stimulated and noradrenaline-stimulated lipolysis in isolated adipocytes were determined. Results Adipocytes were significantly larger in the obese versus the lean women and in subcutaneous versus omental fat. Expressed as a function of cell number, basal lipolysis and noradrenaline responsiveness were higher in subcutaneous versus omental adipocytes from the obese women (P Conclusion In both fat depots, a reduced perilipin protein expression was observed in women obesity. Perilipin protein level may contribute to differences in basal lipolysis and in adipocyte size between fat depots and may regulate lipid accumulation in adipocytes. Differences in hormone-sensitive lipase subcellular distribution were reported between fat depots in the obese women.

  19. Tests of the higher order turbulence model for atmospheric circulations (HOTMAC) at Deseret Chemical Depot

    Energy Technology Data Exchange (ETDEWEB)

    Costigan, K.R.

    1998-11-01

    Deseret Chemical Depot is one of the US Army`s storage facilities for its stockpile of chemical weapon agents. Congress has directed the Department of Defense to eliminate the aging stockpiles, which have existed since the end of World War II, and the US Army is destroying these lethal chemical munitions. Although the danger is slight, accurate predictions of the wind field in the valley are necessary for dispersion calculations in the event of an accident involving toxic chemicals at the depot. There are several small communities in Rush and Tooele valleys, including the town of Tooele, and Salt Lake City is located 65 km to the Northeast of Deseret Chemical Depot South area, at 1,300 m MSL and beyond the Oquirrh Mountains. The purpose of this report is to carry out three-dimensional numerical simulations of the atmospheric circulations in the region around Deseret Chemical Depot with the Higher Order Turbulence Model for Atmospheric Circulations (HOTMAC) and to evaluate the performance of the model. The code had been modified to assimilate local meteorological observations through the use of Newtonian nudging. The nudging scheme takes advantage of the extensive network of local observations in the valley.

  20. Current trend in drug delivery considerations for subcutaneous insulin depots to treat diabetes.

    Science.gov (United States)

    P V, Jayakrishnapillai; Nair, Shantikumar V; Kamalasanan, Kaladhar

    2017-05-01

    Diabetes mellitus (DM) is a metabolic disorder due to irregularities in glucose metabolism, as a result of insulin disregulation. Chronic DM (Type 1) is treated by daily insulin injections by subcutaneous route. Daily injections cause serious patient non-compliance and medication non-adherence. Insulin Depots (ID) are parenteral formulations designed to release the insulin over a specified period of time, to control the plasma blood glucose level for intended duration. Physiologically, pancreas produces and secretes insulin in basal and pulsatile mode into the blood. Delivery systems mimicking basal release profiles are known as open-loop systems and current marketed products are open-loop systems. Future trend in open-loop systems is to reduce the number of injections per week by enhancing duration of action, by modifying the depot properties. The next generation technologies are closed-loop systems that mimic the pulsatile mode of delivery by pancreas. In closed-loop systems insulin will be released in response to plasma glucose. This review focuses on future trend in open-loop systems; by understanding (a) the secretion of insulin from pancreas, (b) the insulin regulation normal and in DM, (c) insulin depots and (d) the recent progress in open-loop depot technology particularly with respect to nanosystems. Copyright © 2017 Elsevier B.V. All rights reserved.

  1. Pharmacodynamic effects of depot-medroxyprogesterone acetate (DMPA) administered to lactating women on their male infants

    NARCIS (Netherlands)

    Virutamasen, P; Leepipatpaiboon, S; Kriengsinyot, R; Vichaidith, P; Muia, PN; SekaddeKigondu, CB; Mati, JKG; Forest, MG; Dikkeschei, LD; Wolthers, BG; dArcangues, C

    1996-01-01

    Normal postpartum women, who had a spontaneous vaginal delivery of one full-term male infant, free of congenital abnormalities and other diseases, were recruited for this study. Thirteen women received 150 mg depot-medroxyprogesterone acetate (DMPA), intramuscularly on days 42 + 1 and 126 + 1 postpa

  2. Discussion on Switch Signal Control of Section Crossover in Station with Multiple Depots%并场车站场间渡线道岔信号控制方案探讨

    Institute of Scientific and Technical Information of China (English)

    王建龙

    2015-01-01

    并列车场场间渡线实现了跨场跨线列车运行,但其站场布置对信号控制系统要求较高。对设置场联轨道区段和调车信号机、双动道岔双控信号等场间渡线道岔控制方案进行研究分析,并进一步提出渡线道岔分场控制及经衔接道岔定反位进路敌对照查防护的平行隔开解决方案,既满足了跨线列车运行要求,又保证了运营安全。%The section crossover employed in station with multiple depots has made it possible to allow trains to run cross depots and lines. However the station layout requires highly for the signal control system. In this paper, the control scheme of setting section crossover for track section between depots, shunting signal and dual control signal of the double acting turnout are investigated. Further, solutions to control the split field with respect to the section crossover at the turnout and to the design of parallel partition rival-examined protection via connecting turnouts are proposed, which can meet operating requirement for cross-line train and guarantee operation safety.

  3. SRNL PHASE 1 ASSESSMENT OF THE WAC/DQO AND UNIT OPERATIONS FOR THE WTP WASTE QUALIFICATION PROGRAM

    Energy Technology Data Exchange (ETDEWEB)

    Peeler, D.; Adamson, D.; Bannochie, C.; Cozzi, A.; Eibling, R.; Hay, M.; Hansen, E.; Herman, D.; Martino, C.; Nash, C.; Pennebaker, F.; Poirier, M.; Reboul, S.; Stone, M.; Taylor-Pashow, K.; White, T.; Wilmarth, B.

    2012-05-16

    The Hanford Tank Waste Treatment and Immobilization Plant (WTP) is currently transitioning its emphasis from a design and construction phase toward start-up and commissioning. With this transition, the WTP Project has initiated more detailed assessments of the requirements related to actual processing of the Hanford Site tank waste. One particular area of interest is the waste qualification program to be implemented to support the WTP. Given the successful implementation of similar waste qualification efforts at the Savannah River Site (SRS), based on critical technical support and guidance from the Savannah River National Laboratory (SRNL), WTP requested the utilization of subject matter experts from SRNL to support a technology exchange to perform a review of the WTP waste qualification program, discuss the general qualification approach at SRS, and to identify critical lessons learned through the support of DWPF's sludge batch qualification efforts. As part of Phase 1, SRNL subject matter experts in critical technical and/or process areas reviewed specific WTP waste qualification information. The Phase 1 review was a collaborative, interactive, and iterative process between the two organizations. WTP provided specific analytical procedures, descriptions of equipment, and general documentation as baseline review material. SRNL subject matter experts reviewed the information and, as appropriate, requested follow-up information or clarification to specific areas of interest. This process resulted in multiple teleconferences with key technical contacts from both organizations resolving technical issues that lead to the results presented in this report. This report provides the results of SRNL's Phase 1 review of the WAC-DQO waste acceptance criteria and processability parameters, and the specific unit operations which are required to support WTP waste qualification efforts. The review resulted in SRNL providing concurrence, alternative methods, or gap

  4. (*) Central Growth Factor Loaded Depots in Bone Tissue Engineering Scaffolds for Enhanced Cell Attraction.

    Science.gov (United States)

    Quade, Mandy; Knaack, Sven; Akkineni, Ashwini Rahul; Gabrielyan, Anastasia; Lode, Anja; Rösen-Wolff, Angela; Gelinsky, Michael

    2017-08-01

    Tissue engineering, the application of stem and progenitor cells in combination with an engineered extracellular matrix, is a promising strategy for bone regeneration. However, its success is limited by the lack of vascularization after implantation. The concept of in situ tissue engineering envisages the recruitment of cells necessary for tissue regeneration from the host environment foregoing ex vivo cell seeding of the scaffold. In this study, we developed a novel scaffold system for enhanced cell attraction, which is based on biomimetic mineralized collagen scaffolds equipped with a central biopolymer depot loaded with chemotactic agents. In humid milieu, as after implantation, the signaling factors are expected to slowly diffuse out of the central depot forming a gradient that stimulates directed cell migration toward the scaffold center. Heparin, hyaluronic acid, and alginate have been shown to be capable of depot formation. By using vascular endothelial growth factor (VEGF) as model factor, it was demonstrated that the release kinetics can be adjusted by varying the depot composition. While alginate and hyaluronic acid are able to reduce the initial burst and prolong the release of VEGF, the addition of heparin led to a much stronger retention that resulted in an almost linear release over 28 days. The biological activity of released VEGF was proven for all variants using an endothelial cell proliferation assay. Furthermore, migration experiments with endothelial cells revealed a relationship between the degree of VEGF retention and migration distance: cells invaded deepest in scaffolds containing a heparin-based depot indicating that the formation of a steep gradient is crucial for cell attraction. In conclusion, this novel in situ tissue engineering approach, specifically designed to recruit and accommodate endogenous cells upon implantation, appeared highly promising to stimulate cell invasion, which in turn would promote vascularization and finally new

  5. Heat shock proteins: in vivo heat treatments reveal adipose tissue depot-specific effects.

    Science.gov (United States)

    Rogers, Robert S; Beaudoin, Marie-Soleil; Wheatley, Joshua L; Wright, David C; Geiger, Paige C

    2015-01-01

    Heat treatments (HT) and the induction of heat shock proteins (HSPs) improve whole body and skeletal muscle insulin sensitivity while decreasing white adipose tissue (WAT) mass. However, HSPs in WAT have been understudied. The purpose of the present study was to examine patterns of HSP expression in WAT depots, and to examine the effects of a single in vivo HT on WAT metabolism. Male Wistar rats received HT (41°C, 20 min) or sham treatment (37°C), and 24 h later subcutaneous, epididymal, and retroperitoneal WAT depots (SCAT, eWAT, and rpWAT, respectively) were removed for ex vivo experiments and Western blotting. SCAT, eWAT, and rpWAT from a subset of rats were also cultured separately and received a single in vitro HT or sham treatment. HSP72 and HSP25 expression was greatest in more metabolically active WAT depots (i.e., eWAT and rpWAT) compared with the SCAT. Following HT, HSP72 increased in all depots with the greatest induction occurring in the SCAT. In addition, HSP25 increased in the rpWAT and eWAT, while HSP60 increased in the rpWAT only in vivo. Free fatty acid (FFA) release from WAT explants was increased following HT in the rpWAT only, and fatty acid reesterification was decreased in the rpWAT but increased in the SCAT following HT. HT increased insulin responsiveness in eWAT, but not in SCAT or rpWAT. Differences in HSP expression and induction patterns following HT further support the growing body of literature differentiating distinct WAT depots in health and disease.

  6. Structured expert elicitation about Listeria monocytogenes cross-contamination in the environment of retail deli operations in the United States.

    Science.gov (United States)

    Hoelzer, Karin; Oliver, Haley F; Kohl, Larry R; Hollingsworth, Jill; Wells, Martin T; Wiedmann, Martin

    2012-07-01

    Listeria monocytogenes is among the foodborne pathogens with the highest death toll in the United States. Ready-to-eat foods contaminated at retail are an important source of infection. Environmental sites in retail deli operations can be contaminated. However, commonly contaminated sites are unlikely to come into direct contact with food and the public health relevance of environmental contamination has remained unclear. To identify environmental sites that may pose a considerable cross-contamination risk, to elucidate potential transmission pathways, and to identify knowledge gaps, we performed a structured expert elicitation of 41 experts from state regulatory agencies and the food retail industry with practical experience in retail deli operations. Following the "Delphi" method, the elicitation was performed in three consecutive steps: questionnaire, review and discussion of results, second questionnaire. Hands and gloves were identified as important potential contamination sources. However, bacterial transfers to and from hands or gloves represented a major data gap. Experts agreed about transfer probabilities from cutting boards, scales, deli cases, and deli preparation sinks to product, and about transfer probabilities from floor drains, walk-in cooler floors, and knife racks to food contact surfaces. Comparison of experts' opinions to observational data revealed a tendency among experts with certain demographic characteristics and professional opinions to overestimate prevalence. Experts' votes clearly clustered into separate groups not defined by place of employment, even though industry experts may have been somewhat overrepresented in one cluster. Overall, our study demonstrates the value and caveats of expert elicitation to identify data gaps and prioritize research efforts.

  7. Downstream process synthesis for biochemical production of butanol, ethanol, and acetone from grains: generation of optimal and near-optimal flowsheets with conventional operating units.

    Science.gov (United States)

    Liu, Jiahong; Fan, L T; Seib, Paul; Friedler, Ferenc; Bertok, Botond

    2004-01-01

    Manufacturing butanol, ethanol, and acetone through grain fermentation has been attracting increasing research interest. In the production of these chemicals from fermentation, the cost of product recovery constitutes the major portion of the total production cost. Developing cost-effective flowsheets for the downstream processing is, therefore, crucial to enhancing the economic viability of this manufacturing method. The present work is concerned with the synthesis of such a process that minimizes the cost of the downstream processing. At the outset, a wide variety of processing equipment and unit operations, i.e., operating units, is selected for possible inclusion in the process. Subsequently, the exactly defined superstructure with minimal complexity, termed maximal structure, is constructed from these operating units with the rigorous and highly efficient graph-theoretic method for process synthesis based on process graphs (P-graphs). Finally, the optimal and near-optimal flowsheets in terms of cost are identified.

  8. The relationship between in-hospital mortality, readmission into the intensive care nursing unit and/or operating theatre and nurse staffing levels.

    Science.gov (United States)

    Diya, Luwis; Van den Heede, Koen; Sermeus, Walter; Lesaffre, Emmanuel

    2012-05-01

      The aim of this article was to assess the relationship between (1) in-hospital mortality and/or (2) unplanned readmission to intensive care units or operating theatre and nurse staffing variables.   Adverse events are used as surrogates for patient safety in nurse staffing and patient safety research. A single adverse event cannot adequately capture the multi-dimensional attributes of patient safety; hence, there is a need to consider composite measures. Unplanned readmission into the postoperative Intensive Care nursing unit and/or operating Theatre and in-hospital mortality can be viewed as measures that incorporate the effects of several adverse events.   We conducted a Bayesian multilevel analysis on a subset of the 2003 Belgian Hospital Discharge and Nursing Minimum Data sets. The sample included 9054 patients who underwent coronary artery bypass surgery or heart valve procedures from 28 Belgian acute hospitals. Two proxies of patient safety were considered, namely postoperative in-hospital mortality in the first postoperative intensive care unit and unplanned readmission into the intensive care and/or operating theatre (including mortality beyond the first postoperative intensive care unit) after the first-operative intensive care nursing unit.   There is an association between in-hospital mortality and/or unplanned readmissions and nurse staffing levels, but the relationship is moderated by volume and severity of illness respectively. In addition, the relationship differs between the two endpoints.   Higher nurse staffing levels on postoperative general nursing cardiac surgery units protected patients from unplanned readmission to intensive care units or operating theatre and in-hospital mortality. © 2011 Blackwell Publishing Ltd.

  9. Validation of the Algorithm for Depot TCTO Labor Costs for the Component Support Cost System (D160B).

    Science.gov (United States)

    2014-09-26

    AD-AI5? 461 VALIDATION OF THE ALGORITHM FOR DEPOT TCTO LABOR COSTS / FOR THE COMPONENT.. (U) INFORMATION SPECTRUM INC ARLINGTON VA S J EINHORN 12 APR...U VALIDATION OF THE ALGORITHM FOR DEPOT TCTO LABOR COSTS I FOR C THE COMPONENT SUPPORT COST SYSTEM (D160B) Contract No. F33600-82-C-0543 12 April 1984...tasks," including a user survey. This report provides the verification and validation of the algorithm called "Depot TCTO Labor Costs." The costs of

  10. Operation Summary of the Urea Low Pressure Hydrolysis Unit%尿素低压水解装置运行小结

    Institute of Scientific and Technical Information of China (English)

    冯培运

    2013-01-01

      介绍该厂自行设计的低压水解系统工艺流程,技术特点,装置投运后的情况,以及产生的经济效益。%  The urea low pressure hydrolysis unit technological process is designed by the technical staffs of the plant . This paper desbcribes the process flow , technical characteristics , unit operation and economic benefits .

  11. Remedial investigation work plan for the Groundwater Operable Unit at Oak Ridge National Laboratory, Oak Ridge, Tennessee

    Energy Technology Data Exchange (ETDEWEB)

    1994-03-01

    This Remedial Investigation (RI) Work Plan has been developed as part of the US Department of Energy`s (DOE`s) investigation of the Groundwater Operable Unit (GWOU) at Oak Ridge National Laboratory (ORNL) located near Oak Ridge, Tennessee. The first iteration of the GWOU RI Work Plan is intended to serve as a strategy document to guide the ORNL GWOU RI. The Work Plan provides a rationale and organization for groundwater data acquisition, monitoring, and remedial actions to be performed during implementation of environmental restoration activities associated with the ORNL GWOU. It Is important to note that the RI Work Plan for the ORNL GWOU is not a prototypical work plan. The RI will be conducted using annual work plans to manage the work activities, and task reports will be used to document the results of the investigations. Sampling and analysis results will be compiled and reported annually with a review of data relative to risk (screening level risk assessment review) for groundwater. This Work Plan outlines the overall strategy for the RI and defines tasks which are to be conducted during the initial phase of investigation. This plan is presented with the understanding that more specific addenda to the plan will follow.

  12. Aquatic invertebrate sampling at selected outfalls in Operable Unit 1082; Technical areas 9, 11, 16 and 22

    Energy Technology Data Exchange (ETDEWEB)

    Cross, S.

    1995-09-01

    The Ecological Studies Team (EST) of ESH-20 at Los Alamos National Laboratory conducted preliminary aquatic sampling at outfalls within Operable Unit 1082 and nearby natural waterways. Eleven outfalls were sampled a total of eighteen times. Three natural waterways (upper Pajarito Canyon, Starmer`s Gulch, and Bulldog Spring) in the vicinity were sampled a total of six times. At most sites, EST recorded hydrological condition, physico-chemical parameters, wildlife uses, and vegetation. At each outfall with water and each natural waterway, EST collected an aquatic invertebrate sample which was analyzed by taxa composition, Wilhm`s biodiversity index, the community tolerance quotient (CTQ), and density. The physico-chemical parameters at most outfalls and natural waterways fell within the normal range of natural waters in the area. However, the outfalls are characterized by low biodiversity and severely stressed communities composed of a restricted number of taxa. The habitat at the other outfalls could probably support well-developed aquatic communities if sufficient water was available. At present, the hydrology at these outfalls is too slight and/or sporadic to support such a community in the foreseeable future. In contrast to the outfalls, the natural waterways of the area had greater densities of aquatic invertebrates, higher biodiversities, and lower CTQs.

  13. Confirmatory Sampling and Analysis Plan for the Lower East Fork Poplar Creek operable unit, Oak Ridge, Tennessee

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-04-01

    On December 21, 1989, the EPA placed the US Department of Energy`s (DOE`s) Oak Ridge Reservation (ORR) on the National Priorities List (NPL). On January 1, 1992, a Federal Facilities Agreement (FFA) between the DOE Field Office in Oak Ridge (DOE-OR), EPA Region IV, and the Tennessee Department of Environment and Conservation (TDEC) went into effect. This FFA establishes the procedural framework and schedule by which DOE-OR will develop, coordinate, implement and monitor environmental restoration activities on the ORR in accordance with applicable federal and state environmental regulations. The DOE-OR Environmental Restoration Program for the ORR addresses the remediation of areas both within and outside the ORR boundaries. This sampling and analysis plan focuses on confirming the cleanup of the stretch of EFPC flowing from Lake Reality at the Y-12 Plant through the City of Oak Ridge, to Poplar Creek on the ORR and its associated floodplain. Both EFPC and its floodplain have been contaminated by releases from the Y-12 Plant since the mid-1950s. Because the EFPC site-designated as an ORR operable unit (OU) under the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) is included on the NPL, its remediation must follow the specific procedures mandated by CERCLA, as amended by the Superfund Amendments and Reauthorization Act in 1986.

  14. Operable Unit 3-13, Group 3, Other Surface Soils Remediation Sets 4-6 (Phase II) Remedial Design/Remedial Action Work Plan

    Energy Technology Data Exchange (ETDEWEB)

    D. E. Shanklin

    2006-06-01

    This Remedial Design/Remedial Action Work Plan provides the framework for defining the remedial design requirements, preparing the design documentation, and defining the remedial actions for Waste Area Group 3, Operable Unit 3-13, Group 3, Other Surface Soils, Remediation Sets 4-6 (Phase II) located at the Idaho Nuclear Technology and Engineering Center at the Idaho National Laboratory. This plan details the design developed to support the remediation and disposal activities selected in the Final Operable Unit 3-13, Record of Decision.

  15. Design, construction, operation and evaluation of a prototype anthracite culm combustion boiler unit. Facility test plan: startup and shakedown, parametric studies and long term operation

    Energy Technology Data Exchange (ETDEWEB)

    1981-06-01

    This proposed performance study is to be performed in the anthracite culm prototype boiler located at Paxinos, Pennsylvania. The boiler is designed to produce 23,400 lb/hr of steam of 200 psig. Effects of operating variables on combustion efficiency, sulfur retention, erosion and corrosion will be analyzed during the runs. The boiler will be operated to determine its technical, economic and environmental performance and to project the viability of it for commercial operation. After the initial testing, the boiler performance will be evaluated over the long term operation.

  16. The role of training in effective simulated self-injection of subcutaneous depot medroxyprogesterone acetate: observations from a usability study.

    Science.gov (United States)

    Kaplan, Irina; Ross, Douglas; Hilton, Fiona; Morgenstern, Diana; Wolter, Kevin

    2016-10-01

    The need for quarterly clinic visits is a barrier to use of subcutaneous depot medroxyprogesterone acetate (DMPA-SC) contraception. The ability to self-inject at home may enhance method acceptance. Since efficacy depends on proper administration, we evaluated whether women could correctly perform simulated injections of DMPA-SC in a Uniject™ injection system using printed Instructions for Use (IFU), with and without hands-on training. Adult female volunteers (N=120) injected DMPA-SC into a rubber trainer at two visits, 3 months apart. Women were randomly assigned to receive hands-on training before the first injection or no training. The primary outcome was the proportion of women who successfully operated the injection system. An attempt was defined as successful if the participant correctly performed all critical steps in the injection procedure (getting ready, selecting an injection area, preparing the injector, mixing the medicine, activating the injector, injecting the dose) and expelled the dose without unexpected interruption. The success rate at month 3 was considered the primary endpoint. A one-sided 95% confidence limit >80% was used to declare the delivery system and IFU "fit for purpose." With training, the success rate (one-sided 95% confidence limit) was 90.0% (81.8%) at day 1 and 96.7% (90.4%) at month 3; without training, rates were 76.7% (66.7%) and 88.3% (79.8%), respectively. The trained (96.4%) and untrained (92.2%) groups successfully completed injecting into the trainer at first injection, the final critical step of the injection procedure, despite the fact that about one third of participants considered expelling depot medroxyprogesterone acetate (one component of this step) to be difficult. Most participants understood the IFU and successfully operated the injection system. Initial hands-on training improved success rates at both visits. For women interested in self-injection, providers should review all steps of the IFU, provide a

  17. Monticello Mill Tailings Site Operable Unit III Annual Groundwater Report May 2014 Through April 2015, October 2015

    Energy Technology Data Exchange (ETDEWEB)

    Nguyen, Jason [USDOE Office of Legacy Management, Washington, DC (United States); Smith, Fred [Navarro Research and Engineering, Inc., Oak Ridge, TN (United States)

    2015-10-01

    This report provides the annual analysis of water quality restoration progress, cumulative through April 2015, for Operable Unit (OU) III, surface water and groundwater, of the U.S. Department of Energy (DOE) Office of Legacy Management Monticello Mill Tailings Site (MMTS). The MMTS is a Comprehensive Environmental Response, Compensation, and Liability Act National Priorities List site located in and near the city of Monticello, San Juan County, Utah. MMTS comprises the 110-acre site of a former uranium- and vanadium-ore-processing mill (mill site) and 1,700 acres of surrounding private and municipal property. Milling operations generated 2.5 million cubic yards of waste (tailings) from 1942 to 1960. The tailings were impounded at four locations on the mill site. Inorganic constituents in the tailings drained from the impoundments to contaminate local surface water (Montezuma Creek) and groundwater in the underlying alluvial aquifer. Mill tailings dispersed by wind and water also contaminated properties surrounding and downstream of the mill site. Remedial actions to remove and isolate radiologically contaminated soil, sediment, and debris from the former mill site (OU I) and surrounding properties (OU II) were completed in 1999 with the encapsulation of the wastes in an engineered repository located on DOE property 1 mile south of the former mill site. Contamination of groundwater and surface water remains within OU III at levels that exceed water quality protection standards. Uranium is the primary contaminant of concern. LM implemented monitored natural attenuation with institutional controls as the OU III remedy in 2004. Because groundwater restoration proceeded more slowly than expected and did not meet performance criteria established in the OU III Record of Decision (June 2004), LM implemented a contingency action in 2009 by an Explanation of Significant Difference to include a pump-and-treat system using a single extraction well and treatment by zero

  18. In vivo determination of subcutaneous and abdominal adipose tissue depots in German Holstein dairy cattle.

    Science.gov (United States)

    Raschka, C; Ruda, L; Wenning, P; von Stemm, C-I; Pfarrer, C; Huber, K; Meyer, U; Dänicke, S; Rehage, J

    2016-07-01

    Ultrasonography was used as a noninvasive method for quantitative estimation of the subcutaneous and abdominal adipose tissue depots in dairy cattle. The prediction model was created and validated with a total of 29 German Holstein cows; 6 were in early lactation (≤100 d in milk [DIM]) and 16 were in advanced lactation (101 to 292 DIM). Seven cows were nonpregnant and nonlactating and had been off milk for 350 to 450 d. Transcutaneous assessment of the thickness of subcutaneous and retroperitoneal adipose tissue was done at 16 sites on the body surface of all cows. After completion of the ultrasonographic measurements, the cows were slaughtered and the adipose depots were separately weighed. A stepwise multivariate regression analysis of the ultrasonographic variables was performed to estimate the slaughter weights of the different fat depots. Slaughter weights of the fat depots ranged from 5.0 to 43.0 kg for subcutaneous adipose tissue (SCAT), from 13.7 to 98.8 kg for abdominal adipose tissue (AAT), from 3.4 to 30.3 kg for retroperitoneal adipose tissue (RPAT), from 5.2 to 39.6 kg for omental adipose tissue (OMAT), and from 4.0 to 35.8 kg for mesenteric adipose tissue (MAT). The relationship between calculated amount of fat and slaughter weight of fat had coefficients of determination () and root mean square errors (kg) of 0.88 and 3.4, respectively, for SCAT; 0.94 and 6.1, respectively, for AAT; 0.94 and 1.7, respectively, for RPAT; 0.83 and 3.2, respectively, for OMAT; and 0.95 and 1.6, respectively, for MAT. The accuracy of ultrasonographic measurement of the different fat depots appears sufficient for the quantitative assessment of internal and subcutaneous fat stores in cows. This method is noninvasive and therefore allows safe and repeated monitoring of the amount of stored fat in different adipose tissue depots of German Holsteins cows.

  19. Maternal obesity programs increased leptin gene expression in rat male offspring via epigenetic modifications in a depot-specific manner

    Directory of Open Access Journals (Sweden)

    Simon Lecoutre

    2017-08-01

    Conclusions: Consistent with the DOHaD hypothesis, persistent epigenetic remodeling occurs at regulatory regions especially within intergenic sequences, linked to higher leptin gene expression in adult HF offspring in a depot-specific manner.

  20. Effects of ovariectomy and resistance training on lipid content in skeletal muscle, liver, and heart; fat depots; and lipid profile

    National Research Council Canada - National Science Library

    Baldissera, Vilmar; de Andrade Perez, Sérgio Eduardo; Prestes, Jonato; Domingos, Mateus Moraes; Shiguemoto, Gilberto Eiji; Pereira, Guilherme Borges; Bernardes, Celene Fernandes; Duarte, Josiane Oliveira; Leite, Richard Diego

    2009-01-01

    The aim of the present study was to investigate the effects of resistance training on skeletal muscle lipid content, liver lipid content, heart lipid content, fat depots, and lipid profile in ovariectomized rats...

  1. To Ensure the Integrity of the Cryogenic Propellant Depot Tank Within the Expected Radiation and Space Debris Environment Project

    Data.gov (United States)

    National Aeronautics and Space Administration — We intend to develop the technology for lightweight composite structure suitable for both cryogenic fuel depot storage as well as human in-space habitat. These will...

  2. Shape Memory Alloy Cryogenic Transfer Coupling for Space Depot Docking Operations Project

    Data.gov (United States)

    National Aeronautics and Space Administration — In the proposed effort, we will demonstrate the feasibility of SMA-based actuation system by designing and fabricating a prototype sub-component of a locking...

  3. Groundwater geochemical and selected volatile organic compound data, Operable Unit 1, Naval Undersea Warfare Center, Division Keyport, Washington, June 2011

    Science.gov (United States)

    Huffman, Raegan L.; Frans, L.M.

    2012-01-01

    Previous investigations indicate that concentrations of chlorinated volatile organic compounds are substantial in groundwater beneath the 9-acre former landfill at Operable Unit 1, Naval Undersea Warfare Center, Division Keyport, Washington. Phytoremediation combined with ongoing natural attenuation processes was the preferred remedy selected by the U.S. Navy, as specified in the Record of Decision for the site. The U.S. Navy planted two hybrid poplar plantations on the landfill in spring 1999 to remove and to control the migration of chlorinated volatile organic compounds in shallow groundwater. The U.S. Geological Survey has continued to monitor groundwater geochemistry to ensure that conditions remain favorable for contaminant biodegradation as specified in the Record of Decision. This report presents groundwater geochemical and selected volatile organic compound data collected at Operable Unit 1 by the U.S. Geological Survey during June 20-22, 2011, in support of long-term monitoring for natural attenuation. In 2011, groundwater samples were collected from 13 wells and 9 piezometers. Samples from all wells and piezometers were analyzed for redox sensitive constituents and dissolved gases, and samples from 5 of 13 wells and all piezometers also were analyzed for chlorinated volatile organic compounds. Concentrations of redox sensitive constituents measured in 2011 were consistent with previous years, with dissolved oxygen concentrations all at 0.4 milligram per liter or less; little to no detectable nitrate; abundant dissolved manganese, iron, and methane; and commonly detected sulfide. The reductive declorination byproducts - methane, ethane, and ethene - were either not detected in samples collected from the upgradient wells in the landfill and the upper aquifer beneath the northern phytoremediation plantation or were detected at concentrations less than those measured in 2010. Chlorinated volatile organic compound concentrations in 2011 at most piezometers

  4. Remedial investigation/feasibility study for the Clinch River/Poplar Creek operable unit. Volume 3. Appendix E

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-09-01

    This document contains Appendix E: Toxicity Information and Uncertainty Analysis, description of methods, from the combined Remedial Investigation/Feasibility Study Report for the Clinch River/Poplar Crack (CR/PC) Operable Unit (OU). The CR/PC OU is located in Anderson and Roane Counties, Tennessee and consists of the Clinch River and several of its embayments in Melton Hill and Watts Bar Reservoirs. These waters have received hazardous substances released over a period of 50 years from the US Department of Energy`s Oak Ridge Reservation (ORR), a National Priority List site established under the Comprehensive Environmental Response, Compensation, and Liability Act. A remedial investigation has been conducted to determine the current nature and extent of any contamination and to assess the resulting risk to human health and the environment. The feasibility study evaluates remedial action alternatives to identify any that are feasible for implementation and that would effectively reduce risk. Historical studies had indicated that current problems would likely include {sup 137}Cs in sediment of the Clinch River, mercury in sediment and fish of Poplar Creek and PCBs and pesticides in fish from throughout the OU. Peak releases of mercury and {sup 137}Cs occurred over 35 years ago, and current releases are low. Past releases of PCBs from the ORR are poorly quantified, and current releases are difficult to quantify because levels are so low. The site characterization focused on contaminants in surface water, sediment, and biota. Contaminants in surface water were all found to be below Ambient Water Quality Criteria. Other findings included the following: elevated metals including cesium 137 and mercury in McCoy Branch sediments; PCBs and chlordane elevated in several fish species, presenting the only major human health risk, significant ecological risks in Poplar Creek but not in the Clinch River.

  5. Remedial investigation/feasibility study of the Clinch River/Poplar Creek operable unit. Volume 1, main text

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-01

    This document is the combined Remedial Investigation/Feasibility Study (RI/FS) Report for the Clinch River/Poplar Creek Operable Unit (CR/PC OU), an off-site OU associated with environmental restoration activities at the U.S. Department of Energy (DOE) Oak Ridge Reservation (ORR). As a result of past, present, and potential future releases of hazardous substances into the environment, the ORR was placed on the National Priorities List in December 1989 (54 FR 48184). Sites on this list must be investigated for possible remedial action, as required by the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA, 42 U.S.C. 9601, et seq.). This report documents the findings of the remedial investigation of this OU and the feasibility of potential remedial action alternatives. These studies are authorized by Sect. 117 of CERCLA and were conducted in accordance with the requirements of the National Contingency Plan (40 CFR Part 300). DOE, the U.S. Environmental Protection Agency (EPA), and the Tennessee Department of Environment and Conservation (TDEC) have entered into a Federal Facility Agreement (FFA), as authorized by Sect. 120 of CERCLA and Sects. 3008(h) and 6001 of the Resource Conservation and Recovery Act (RCRA) (42 U.S.C. 6901, et seq.). The purpose of this agreement is to ensure a coordinated and effective response for all environmental restoration activities occurring at the ORR. In addition to other responsibilities, the FFA parties mutually define the OU boundaries, set remediation priorities, establish remedial investigation priorities and strategies, and identify and select remedial actions. A copy of this FFA is available from the DOE Information Resource Center in Oak Ridge, Tennessee.

  6. Bioassay of estrogenicity and chemical analyses of estrogens in streams across the United States associated with livestock operations

    Science.gov (United States)

    Alvarez, David A.; Shappell, Nancy W.; Billey, L.O.; Bermudez, Dietrich S.; Wilson, Vickie S.; Kolpin, Dana W.; Perkins, Stephanie D.; Evans, Nicola; Foreman, William T.; Gray, James L.; Shipitalo, J.M.; Meyer, Michael T.

    2013-01-01

    Animal manures, used as a nitrogen source for crop production, are often associated with negative impacts on nutrient levels in surface water. The concentrations of estrogens in streams from these manures also are of concern due to potential endocrine disruption in aquatic species. Streams associated with livestock operations were sampled by discrete samples (n = 38) or by time-integrated polar organic chemical integrative samplers (POCIS,n = 19). Samples were analyzed for estrogens by gas chromatography-tandem mass spectrometry (GC-MSM2) and estrogenic activity was assessed by three bioassays: Yeast Estrogen Screen (YES), T47D-KBluc Assay, MCF-7 Estrogenicity Screen (E-Screen). Samples were collected from 19 streams within small (∼1-30 km2) watersheds in 12 U.S. states representing a range of hydrogeologic conditions, dominated by: dairy (3), grazing beef (3), feedlot cattle (1); swine (5); poultry (3); and 4 areas where no livestock were raised or manure was applied. Water samples were consistently below the United Kingdom proposed Lowest Observable Effect Concentration for 17b-estradiol in fish (10 ng/L) in all watersheds, regardless of land use. Estrogenic activity was often higher in samples during runoff conditions following a period of manure application. Estrone was the most commonly detected estrogen (13 of 38 water samples, mean 1.9, maximum 8.3 ng/L). Because of the T47D-KBluc assay’s sensitivity towards estrone (1.4 times 17β-estradiol) it was the most sensitive method for detecting estrogens, followed by the E-Screen, GC-MS2, and YES. POCIS resulted in more frequent detections of estrogens than discrete water samples across all sites, even when applying the less-sensitive YES bioassay to the POCIS extracts.

  7. Remedial investigation/feasibility study for the Clinch River/Poplar Creek operable unit. Volume 1. Main text

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-09-01

    This is the combined Remedial Investigation/Feasibility Study Report for the Clinch River/Poplar Crack (CR/PC) Operable Unit (OU). The CR/PC OU is located in Anderson and Roane Counties, Tennessee and consists of the Clinch River and several of its embayments in Melton Hill and Watts Bar Reservoirs. These waters have received hazardous substances released over a period of 50 years from the US Department of Energy`s Oak Ridge Reservation (ORR), a National Priority List site established under the Comprehensive Environmental Response, Compensation, and Liability Act. A remedial investigation has been conducted to determine the current nature and extent of any contamination and to assess the resulting risk to human health and the environment. The feasibility study evaluates remedial action alternatives to identify any that are feasible for implementation and that would effectively reduce risk. Historical studies had indicated that current problems would likely include {sup 137}Cs in sediment of the Clinch River, mercury in sediment and fish of Poplar Creek and PCBs and pesticides in fish from throughout the OU. Peak releases of mercury and {sup 137}Cs occurred over 35 years ago, and current releases are low. Past releases of PCBs from the ORR are poorly quantified, and current releases are difficult to quantify because levels are so low. The site characterization focused on contaminants in surface water, sediment, and biota. Contaminants in surface water were all found to be below Ambient Water Quality Criteria. Other findings included the following: elevated metals including cesium 137 and mercury in McCoy Branch sediments; PCBs and chlordane elevated in several fish species, presenting the only major human health risk, significant ecological risks in Poplar Creek but not in the Clinch River.

  8. Managing Postoperative Analgesic Failure: Tramadol Versus Morphine for Refractory Pain in the Post-Operative Recovery Unit.

    Science.gov (United States)

    Byrne, Kelly; Nolan, Aoife; Barnard, John; Tozer, Megan; Harris, David; Sleigh, Jamie

    2017-02-01

    This study aimed to discover whether co-analgesia with tramadol or additional morphine was more effective for patients who still had severe pain despite being given 10 mg intravenous morphine in the post-anesthesia care unit (PACU). All eligible patients were consented and recruited to the trial pre-operatively, but only a small subgroup – whose pain was not successfully controlled (pain score 6/10 or more) after receiving 10 mg of morphine in the PACU—were then randomized to enter the trial and receive, in a double blinded fashion, the analgesic study drug; which consisted of either a further 10 mg of morphine, or 100 mg of tramadol, titrated intravenously to control their pain. The groups were compared as to: the time to readiness for discharge, the patient’s pain scores over time, and the presence of side effects. There was no statistically significant difference in any of the outcomes measured. The time to readiness for discharge from PACU was 119 minutes in the morphine group and 120 minutes in the tramadol group. However in approximately half the cases who entered the trial (i.e., where pain had not been controlled with the pre-enrollment baseline 10 mg of morphine in PACU) neither a further 10 mg of morphine nor 100 mg of tramadol effectively relieved the patient’s pain. We found no difference between additional morphine and co-analgesia with tramadol in this study. Patients who don’t respond to reasonable doses of opioids in PACU are very likely to be unresponsive to further opioids, and other non-opioid analgesic techniques (such as regional anesthesia) should be considered early in this group of patients.

  9. Examination of Performance Management Targets in Case of an International Corporation’s Eastern Hungarian Operating Unit

    Directory of Open Access Journals (Sweden)

    Nemeth Zoltan

    2016-06-01

    Full Text Available Nowadays, due to the social and economic changes, the human is already the main resource which determines the successfulness of corporations. The expertise in managing the human resources is a key factor of competitiveness therefore it has become a strategic question. Primary aim of the treatise is to outline the most important principles, targets and peculiarities of performance management system, which is a central element of human resource management, as well as its interconnectedness with the individual performance evaluation and human resource development through the mirror of one of today’s biggest Hungarian economic corporations. We aimed to explore, by means of document analysis as well as methods of case study and interview, how the targets of performance management are used for increasing the economic productivity, preserving the competitiveness, retaining and enhancing the satisfaction of workers. It can be stated that the PM system was continuously improved in case of the organization examined because the corporate goals and the expected performances were adjusted to the changing market demands over time but, at the same time the goal of differentiation has remained unchanged. Each worker evaluates his/her performance individually, the base of which is the extent of contribution to the corporate results. Based on the results, it can overall be stated that such a well-functioning performance management system is applied in the operating unit of the corporation examined which is strongly supported by the organizational culture and which contributes to the joint fulfilment of personal as well as organizational goals.

  10. Three operational taxonomic units of Eimeria are common in Nigerian chickens and may undermine effective molecular diagnosis of coccidiosis.

    Science.gov (United States)

    Jatau, Isa D; Lawal, Idris A; Kwaga, Jacob K P; Tomley, Fiona M; Blake, Damer P; Nok, Andrew J

    2016-06-04

    Chicken is fast becoming the world's most consumed meat. As a consequence poultry health is more important now than ever before, with pathogens of chickens recognised as serious threats to food security. One such threat are Eimeria species parasites, protozoa which can cause the disease coccidiosis. Eimeria can compromise economic poultry production and chicken welfare, and have serious consequences for poor livestock keepers. Seven Eimeria species that infect chickens are recognised with a global enzootic distribution. More recently three cryptic Operational Taxonomic Units (OTUx, y and z) have been described in populations of Eimeria recovered from chickens in Australia. Two of the three OTUs have also been detected in sub-Saharan Africa, but their occurrence, pathology and the risk they pose is largely unknown. Nigeria has witnessed a dramatic expansion in poultry production and is now the largest poultry producer in Africa. Here, faecal samples collected from nine of 12 commercial chicken farms sampled in Kaduna state, Nigeria, were found to contain eimerian oocysts. After amplification by in vivo propagation all three cryptic OTU genotypes were detected using polymerase chain reaction (PCR), including OTUy for the first time outside of Australia. Comparison with a widely used, established Eimeria species-specific PCR assay revealed failure to detect the OTU genotypes. All three of the Eimeria OTU genotypes appear to be common in north-western Nigeria. The failure of a leading species-specific molecular assay to detect these genotypes indicates a risk of false negative Eimeria diagnosis when using molecular tools and suggests that the spatial occurrence of each OTU may be far wider than has been recognised. The risk posed by these novel genotypes is unknown, but it is clear that a better understanding of Eimeria occurrence is required together with the validation of effective diagnostics.

  11. Remedial investigation/feasibility study for the Clinch River/Poplar Creek operable unit. Volume 4. Appendix F

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-09-01

    This section contains ecotoxicological profiles for the COPECs for the combined Remedial Investigation/Feasibility Study Report for the Clinch River/Poplar Crack (CR/PC) Operable Unit (OU). The ecotoxicological information is presented for only those endpoints for which the chemicals are COPECs. The CR/PC OU is located in Anderson and Roane Counties, Tennessee and consists of the Clinch River and several of its embayments in Melton Hill and Watts Bar Reservoirs. These waters have received hazardous substances released over a period of 50 years from the US Department of Energy`s Oak Ridge Reservation (ORR), a National Priority List site established under the Comprehensive Environmental Response, Compensation, and Liability Act. A remedial investigation has been conducted to determine the current nature and extent of any contamination and to assess the resulting risk to human health and the environment. The feasibility study evaluates remedial action alternatives to identify any that are feasible for implementation and that would effectively reduce risk. Historical studies had indicated that current problems would likely include {sup 137}Cs in sediment of the Clinch River, mercury in sediment and fish of Poplar Creek and PCBs and pesticides in fish from throughout the OU. Peak releases of mercury and {sup 137}Cs occurred over 35 years ago, and current releases are low. Past releases of PCBs from the ORR are poorly quantified, and current releases are difficult to quantify because levels are so low. The site characterization focused on contaminants in surface water, sediment, and biota. Contaminants in surface water were all found to be below Ambient Water Quality Criteria. Other findings included the following: elevated metals including cesium 137 and mercury in McCoy Branch sediments; PCBs and chlordane elevated in several fish species, presenting the only major human health risk, significant ecological risks in Poplar Creek but not in the Clinch River.

  12. Sampling and analysis plan for treatment water and creek water for the Lower East Fork Poplar Creek Operable Unit, Oak Ridge, Tennessee

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-04-01

    This document provides the Environmental Restoration Program with information about the methodology, organizational structure, quality assurance and health and safety practices to be employed during the water sampling and analysis activities associated with the remediation of the Lower East Fork Poplar Creek Operable Unit during remediation of the National Oceanic and Atmospheric Administration and Bruner sites.

  13. Indication of metal homeostasis disturbance in earthworm Eisenia fetida after exposure to semi-solid depot sludge.

    Science.gov (United States)

    Babić, Sanja; Dragun, Zrinka; Sauerborn Klobučar, Roberta; Ivanković, Dušica; Bačić, Niko; Fiket, Željka; Barišić, Josip; Krasnići, Nesrete; Strunjak-Perović, Ivančica; Topić Popović, Natalija; Čož-Rakovac, Rozelindra

    2015-09-01

    Treated sewage sludge is commonly used in agriculture as fertilizer. It is, therefore, necessary to determine possible detrimental influences of sludge application on soil contamination and accumulation of contaminants in tissues of terrestrial animals, which in the long run could also have undesirable effects on humans. With that aim, the study was performed using earthworm Eisenia fetida as test organism and semi-solid depot sludge from a wastewater treatment plant as exposure media. The concentrations of 26 metals/metalloids were determined in depot sludge, and their bioaccumulation was estimated in whole tissue of E. fetida, and for the first time in the soluble tissue fraction, which represents metal fraction available for metabolic requirements and toxic effects. Obtained results have revealed acceptable levels of several elements (Cd, Cr, Cu, Ni, Pb, Zn) in depot sludge, when compared to currently valid regulations, and only moderate accumulation of some elements (e.g. As, Ba, Cd, Co, Fe, Tl, V, and Zn) in earthworms, as a consequence of exposure to depot sludge. However, a concentration increase after exposure to depot sludge was observed in E. fetida for several elements (Cd, Mo, and Zn), which were present in lower concentrations in the exposure mixtures than in soil. Contrary, a concentration decrease was observed for Cs, Mn, and Rb, although they were present in higher concentrations in depot sludge than in soil. It was an indication of disturbance in metal homeostasis in earthworms, possibly caused by exposure to complex mixture of contaminants present in depot sludge. The cumulative effect of exposure to a number of various contaminants (inorganic, organic, microbiological and pharmaceutical), even if each of them was not present in very high concentrations, could have caused distress in earthworms exposed to depot sludge. Copyright © 2015 Elsevier B.V. All rights reserved.

  14. Army Working Capital Fund: Army Industrial Operations Could Improve Budgeting and Management of Carryover

    Science.gov (United States)

    2016-06-01

    throughs of four Army depot maintenance operations to observe the work being performed and discussed with officials the causes for workload carrying...the preponderance of the Industrial Operations workload . Army Materiel Command (AMC) serves as the management command for Industrial Operations... automotive and Armaments Command LCMC mission of developing, acquiring, fielding, and sustaining ground systems, such as the Mine Resistant Ambush

  15. An Injectable, Click-Cross-Linked Small Intestinal Submucosa Drug Depot for the Treatment of Rheumatoid Arthritis.

    Science.gov (United States)

    Kim, Kyungsook; Park, Ji Hoon; Park, Seung Hun; Lee, Hye Yun; Kim, Jae Ho; Kim, Moon Suk

    2016-12-01

    Here, a click-cross-linked small intestine submucosa (SIS) drug depot is described for the treatment of rheumatoid arthritis (RA). To the best of the knowledge, there have been no studies related to the intra-articular injection of methotrexate (Met)-loaded click-cross-linkable SIS (Met-loaded Cx-SIS) for RA treatment. As the key objective of this work, injectable formulations of tetrazine-modified SIS (TE-SIS) and transcyclooctene-modified SIS (TC-SIS) are employed as drug depots. Within a few seconds, the simple mixing of equal amounts of TE-SIS and TC-SIS suspensions forms a gelatinous click-cross-linked SIS (Cx-SIS) drug depot in vitro and in vivo. The formed Cx-SIS depot is maintained in the articular joint over an extended period, while SIS alone rapidly disappears. Injectable formulations of Met-loaded Cx-SIS and Met-loaded SIS are prepared and then injected into articular joints to form drug depots. Compared to animals treated with Met-loaded SIS, RA animals treated with Met-loaded Cx-SIS show effective RA repair, as well as extensive regeneration of chondrocytes and glycosaminoglycan deposits. Collectively, these results indicate that the Met-loaded Cx-SIS depot is successfully formed after intra-articular injection of click-cross-linkable SIS, and that this formulation induces long-lasting Met release and allows Met to act effectively in the articular joint, resulting in RA repair.

  16. Dermal adipocytes and hair cycling: is spatial heterogeneity a characteristic feature of the dermal adipose tissue depot?

    Science.gov (United States)

    Kruglikov, Ilja L; Scherer, Philipp E

    2016-04-01

    Adipocytes are widely distributed in the dermis, in a unique fat depot referred to as dermal white adipose tissue (dWAT). In rodents, dWAT is present as widespread thin layers, whereas in pigs and humans, it is present in clusters referred to as 'dermal cones' around the pilosebaceous units. This distinct layer of fat cells located above the subcutaneous white adipose tissue is important for proper hair follicle (HF) cycling in rodents. Murine HFs produce spatially restricted synchronous patches after their second postnatal cycle which correlates with the spatial heterogeneity of murine dWAT. Similarly, the cycling of HFs in humans may also be related to the spatial distribution of dWAT, making the difference between murine and human HF cycling of more quantitative than of qualitative nature. This should allow the production of small spatially correlated HF patches in human skin, and we propose that this process can be regulated by paracrine signalling involving a number of signalling modules, including the hedgehog pathway. This pathway is an established player in HF cycling, but is also involved in the regulation of adipogenesis and may therefore be a key regulator of the process across species. We also suggest that the spatial heterogeneity of dWAT is connected not only to HF cycling, but may also be related to other physiological and pathological processes in the skin.

  17. Historic Properties Report: Fort Wingate Depot Activity, New Mexico.

    Science.gov (United States)

    1984-07-01

    the area. Each has projecting wooden roof beams or vigas typical of architecture in the southwestern United States. This nonstandard construction...roof beams or vigas typical of architecture in the southwest. (Source: Field inventory photograph, 1984, Barbara Hightower, Building Technology, Inc

  18. Simultaneously Recovering Rolling Stock Schedules and Depot Plans Under Disruption

    DEFF Research Database (Denmark)

    Haahr, Jørgen Thorlund; Lusby, Richard Martin; Larsen, Jesper

    2015-01-01

    to be applied in a disruption recovery setting. Furthermore, we provide a comparison of several solution strategies to the Train Unit Parking Problem, and, by way of an example prove the heuristic nature of a previously proposed optimal approach. We analyse the performance of the proposed methodology...

  19. Effect of Depot Medroxyprogesterone Acetate (DMPA) on Bone Mineral Density in Women of Reproductive Age

    Institute of Scientific and Technical Information of China (English)

    Ling GAI; Jing-lu ZHANG; Hui-zhen ZHANG; Ping GAI; Yong-hong LIU

    2009-01-01

    Objective To compare bone mineral density (BMD) between users of intramuscular depot medroxyprogesterone acetate(DMPA) and nonhormonal control subjects. Methods The study included 68 women aged between 25 and 40 years using depot medroxyprogesterone acetate for 24 months and 59 women aged between 25 and 40 years using nonhormonal contraception as control subjects. BMD of the lumbar spine and femoral neck were obtained using dual energy X-ray absorptiometry. Results At 24 months of treatment, as compared with baseline, the mean BMD in lumbar spine and femoral neck was decreased by 5.5% and 5.9%, respectively. Lumbar spine and femoral neck BMD in women who used DMPA were significantly decreased compared with the subjects in nonuser (P<0.001). Conclusion These results show BMD declined during using DMPA in women aged 25 -40 years old.

  20. Different adipose tissue depots: Metabolic implications and effects of surgical removal.

    Science.gov (United States)

    Marcadenti, Aline; de Abreu-Silva, Erlon Oliveira

    2015-11-01

    Increased adiposity has been associated to worse metabolic profile, cardiovascular disease, and mortality. There are two main adipose tissue depots in the body, subcutaneous and visceral adipose tissue, which differ in anatomical location. A large body of evidence has shown the metabolic activity of adipose tissue; lipectomy and/or liposuction therefore appear to be alternatives for improving metabolic profile through rapid loss of adipose tissue. However, surgical removal of adipose tissue may be detrimental for metabolism, because subcutaneous adipose tissue has not been associated to metabolic disorders such as insulin resistance and type 2 diabetes mellitus. In addition, animal studies have shown a compensatory growth of adipose tissue in response to lipectomy. This review summarizes the implications of obesity-induced metabolic dysfunction, its relationship with the different adipose tissue depots, and the effects of lipectomy on cardiometabolic risk factors. Copyright © 2015 SEEN. Published by Elsevier España, S.L.U. All rights reserved.