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Sample records for deployable dna analyzer

  1. PDA: Pooled DNA analyzer

    Directory of Open Access Journals (Sweden)

    Lin Chin-Yu

    2006-04-01

    Full Text Available Abstract Background Association mapping using abundant single nucleotide polymorphisms is a powerful tool for identifying disease susceptibility genes for complex traits and exploring possible genetic diversity. Genotyping large numbers of SNPs individually is performed routinely but is cost prohibitive for large-scale genetic studies. DNA pooling is a reliable and cost-saving alternative genotyping method. However, no software has been developed for complete pooled-DNA analyses, including data standardization, allele frequency estimation, and single/multipoint DNA pooling association tests. This motivated the development of the software, 'PDA' (Pooled DNA Analyzer, to analyze pooled DNA data. Results We develop the software, PDA, for the analysis of pooled-DNA data. PDA is originally implemented with the MATLAB® language, but it can also be executed on a Windows system without installing the MATLAB®. PDA provides estimates of the coefficient of preferential amplification and allele frequency. PDA considers an extended single-point association test, which can compare allele frequencies between two DNA pools constructed under different experimental conditions. Moreover, PDA also provides novel chromosome-wide multipoint association tests based on p-value combinations and a sliding-window concept. This new multipoint testing procedure overcomes a computational bottleneck of conventional haplotype-oriented multipoint methods in DNA pooling analyses and can handle data sets having a large pool size and/or large numbers of polymorphic markers. All of the PDA functions are illustrated in the four bona fide examples. Conclusion PDA is simple to operate and does not require that users have a strong statistical background. The software is available at http://www.ibms.sinica.edu.tw/%7Ecsjfann/first%20flow/pda.htm.

  2. A Portable, Field-Deployable Analyzer for Isotopic Water Measurements

    Science.gov (United States)

    Berman, E. S.; Gupta, M.; Huang, Y. W.; Lacelle, D.; McKay, C. P.; Fortson, S.

    2015-12-01

    Water stable isotopes have for many years been used to study the hydrological cycle, catchment hydrology, and polar climate among other applications. Typically, discrete water samples are collected and transported to a laboratory for isotope analysis. Due to the expense and labor associated with such sampling, isotope studies have generally been limited in scope and time-resolution. Field sampling of water isotopes has been shown in recent years to provide dense data sets with the increased time resolution illuminating substantially greater short term variability than is generally observed during discrete sampling. A truly portable instrument also opens the possibility to utilize the instrument as a tool for identifying which water samples would be particularly interesting for further laboratory investigation. To make possible such field measurements of liquid water isotopes, Los Gatos Research has developed a miniaturized, field-deployable liquid water isotope analyzer. The prototype miniature liquid water isotope analyzer (mini-LWIA) uses LGR's patented Off-Axis ICOS (Integrated Cavity Output Spectroscopy) technology in a rugged, Pelican case housing for easy transport and field operations. The analyzer simultaneously measures both δ2H and δ18O from liquid water, with both manual and automatic water introduction options. The laboratory precision for δ2H is 0.6 ‰, and for δ18O is 0.3 ‰. The mini-LWIA was deployed in the high Arctic during the summer of 2015 at Inuvik in the Canadian Northwest Territories. Samples were collected from Sachs Harbor, on the southwest coast of Banks Island, including buried basal ice from the Lurentide Ice Sheet, some ice wedges, and other types of ground ice. Methodology and water analysis results from this extreme field deployment will be presented.

  3. High-frequency field-deployable isotope analyzer for hydrological applications

    Science.gov (United States)

    Elena S.F. Berman; Manish Gupta; Chris Gabrielli; Tina Garland; Jeffrey J. McDonnell

    2009-01-01

    A high-frequency, field-deployable liquid water isotope analyzer was developed. The instrument was deployed for 4 contiguous weeks in the H. J. Andrews Experimental Forest Long-term Ecological Research site in western Oregon, where it was used for real-time measurement of the isotope ratios of precipitation and stream water during three large storm events. We were able...

  4. UVB DNA dosimeters analyzed by polymerase chain reactors

    International Nuclear Information System (INIS)

    Yoshida, Hiroko; Regan, J.D.; Florida Inst. of Tech., Melbourne, FL

    1997-01-01

    Purified bacteriophage λ DNA was dried on a UV-transparent polymer film and served as a UVB dosimeter for personal and ecological applications. Bacteriophage λ DNA was chosen because it is commercially available and inexpensive, and its entire sequence is known. Each dosimeter contained two sets of DNA sandwiched between UV-transparent polymer films, one exposed to solar radiation (experimental) and another protected from UV radiation by black paper (control). The DNA dosimeter was then analyzed by a polymerase chain reaction (PCR) that amplifies a 500 base pair specific region of λ DNA. Photoinduced damage in DNA blocks polymerase from synthesizing a new strand; therefore, the amount of amplified product in UV-exposed DNA was reduced from that found in control DNA. The dried λ DNA dosimeter is compact, robust, safe and transportable, stable over long storage times and provides the total UVB dose integrated over the exposure time. (author)

  5. Methyl-Analyzer--whole genome DNA methylation profiling.

    Science.gov (United States)

    Xin, Yurong; Ge, Yongchao; Haghighi, Fatemeh G

    2011-08-15

    Methyl-Analyzer is a python package that analyzes genome-wide DNA methylation data produced by the Methyl-MAPS (methylation mapping analysis by paired-end sequencing) method. Methyl-MAPS is an enzymatic-based method that uses both methylation-sensitive and -dependent enzymes covering >80% of CpG dinucleotides within mammalian genomes. It combines enzymatic-based approaches with high-throughput next-generation sequencing technology to provide whole genome DNA methylation profiles. Methyl-Analyzer processes and integrates sequencing reads from methylated and unmethylated compartments and estimates CpG methylation probabilities at single base resolution. Methyl-Analyzer is available at http://github.com/epigenomics/methylmaps. Sample dataset is available for download at http://epigenomicspub.columbia.edu/methylanalyzer_data.html. fgh3@columbia.edu Supplementary data are available at Bioinformatics online.

  6. University of Tennessee deploys force10 C-series to analyze data from CERN's Large Hadron Collider

    CERN Multimedia

    2007-01-01

    "Force20 networks, the pioneer in building and securing reliable networks, today announced that the University of Tennessee physics department has deployed the C300 resilient switch to analyze data form CERN's Large Hadron Collider." (1 page)

  7. Chromatin immunoprecipitation to analyze DNA binding sites of HMGA2.

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    Nina Winter

    Full Text Available BACKGROUND: HMGA2 is an architectonic transcription factor abundantly expressed during embryonic and fetal development and it is associated with the progression of malignant tumors. The protein harbours three basically charged DNA binding domains and an acidic protein binding C-terminal domain. DNA binding induces changes of DNA conformation and hence results in global overall change of gene expression patterns. Recently, using a PCR-based SELEX (Systematic Evolution of Ligands by Exponential Enrichment procedure two consensus sequences for HMGA2 binding have been identified. METHODOLOGY/PRINCIPAL FINDINGS: In this investigation chromatin immunoprecipitation (ChIP experiments and bioinformatic methods were used to analyze if these binding sequences can be verified on chromatin of living cells as well. CONCLUSION: After quantification of HMGA2 protein in different cell lines the colon cancer derived cell line HCT116 was chosen for further ChIP experiments because of its 3.4-fold higher HMGA2 protein level. 49 DNA fragments were obtained by ChIP. These fragments containing HMGA2 binding sites have been analyzed for their AT-content, location in the human genome and similarities to sequences generated by a SELEX study. The sequences show a significantly higher AT-content than the average of the human genome. The artificially generated SELEX sequences and short BLAST alignments (11 and 12 bp of the ChIP fragments from living cells show similarities in their organization. The flanking regions are AT-rich, whereas a lower conservation is present in the center of the sequences.

  8. Analyzing mobile WiMAX base station deployment under different frequency planning strategies

    Science.gov (United States)

    Salman, M. K.; Ahmad, R. B.; Ali, Ziad G.; Aldhaibani, Jaafar A.; Fayadh, Rashid A.

    2015-05-01

    The frequency spectrum is a precious resource and scarce in the communication markets. Therefore, different techniques are adopted to utilize the available spectrum in deploying WiMAX base stations (BS) in cellular networks. In this paper several types of frequency planning techniques are illustrated, and a comprehensive comparative study between conventional frequency reuse of 1 (FR of 1) and fractional frequency reuse (FFR) is presented. These techniques are widely used in network deployment, because they employ universal frequency (using all the available bandwidth) in their base station installation/configuration within network system. This paper presents a network model of 19 base stations in order to be employed in the comparison of the aforesaid frequency planning techniques. Users are randomly distributed within base stations, users' resource mapping and their burst profile selection are based on the measured signal to interference plus-noise ratio (SINR). Simulation results reveal that the FFR has advantages over the conventional FR of 1 in various metrics. 98 % of downlink resources (slots) are exploited when FFR is applied, whilst it is 81 % at FR of 1. Data rate of FFR has been increased to 10.6 Mbps, while it is 7.98 Mbps at FR of 1. The spectral efficiency is better enhanced (1.072 bps/Hz) at FR of 1 than FFR (0.808 bps/Hz), since FR of 1 exploits all the Bandwidth. The subcarrier efficiency shows how many data bits that can be carried by subcarriers under different frequency planning techniques, the system can carry more data bits under FFR (2.40 bit/subcarrier) than FR of 1 (1.998 bit/subcarrier). This study confirms that FFR can perform better than conventional frequency planning (FR of 1) which made it a strong candidate for WiMAX BS deployment in cellular networks.

  9. A field-deployable compound-specific isotope analyzer based on quantum cascade laser and hollow waveguide

    Science.gov (United States)

    Wu, Sheng; Deev, Andrei

    2013-01-01

    A field deployable Compound Specific Isotope Analyzer (CSIA) coupled with capillary chromatogrpahy based on Quantum Cascade (QC) lasers and Hollow Waveguide (HWG) with precision and chemical resolution matching mature Mass Spectroscopy has been achieved in our laboratory. The system could realize 0.3 per mil accuracy for 12C/13C for a Gas Chromatography (GC) peak lasting as short as 5 seconds with carbon molar concentration in the GC peak less than 0.5%. Spectroscopic advantages of HWG when working with QC lasers, i.e. single mode transmission, noiseless measurement and small sample volume, are compared with traditional free space and multipass spectroscopy methods.

  10. Analyzing mosquito (Diptera: culicidae diversity in Pakistan by DNA barcoding.

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    Muhammad Ashfaq

    Full Text Available Although they are important disease vectors mosquito biodiversity in Pakistan is poorly known. Recent epidemics of dengue fever have revealed the need for more detailed understanding of the diversity and distributions of mosquito species in this region. DNA barcoding improves the accuracy of mosquito inventories because morphological differences between many species are subtle, leading to misidentifications.Sequence variation in the barcode region of the mitochondrial COI gene was used to identify mosquito species, reveal genetic diversity, and map the distribution of the dengue-vector species in Pakistan. Analysis of 1684 mosquitoes from 491 sites in Punjab and Khyber Pakhtunkhwa during 2010-2013 revealed 32 species with the assemblage dominated by Culex quinquefasciatus (61% of the collection. The genus Aedes (Stegomyia comprised 15% of the specimens, and was represented by six taxa with the two dengue vector species, Ae. albopictus and Ae. aegypti, dominant and broadly distributed. Anopheles made up another 6% of the catch with An. subpictus dominating. Barcode sequence divergence in conspecific specimens ranged from 0-2.4%, while congeneric species showed from 2.3-17.8% divergence. A global haplotype analysis of disease-vectors showed the presence of multiple haplotypes, although a single haplotype of each dengue-vector species was dominant in most countries. Geographic distribution of Ae. aegypti and Ae. albopictus showed the later species was dominant and found in both rural and urban environments.As the first DNA-based analysis of mosquitoes in Pakistan, this study has begun the construction of a barcode reference library for the mosquitoes of this region. Levels of genetic diversity varied among species. Because of its capacity to differentiate species, even those with subtle morphological differences, DNA barcoding aids accurate tracking of vector populations.

  11. Application of a clustering-based peak alignment algorithm to analyze various DNA fingerprinting data.

    Science.gov (United States)

    Ishii, Satoshi; Kadota, Koji; Senoo, Keishi

    2009-09-01

    DNA fingerprinting analysis such as amplified ribosomal DNA restriction analysis (ARDRA), repetitive extragenic palindromic PCR (rep-PCR), ribosomal intergenic spacer analysis (RISA), and denaturing gradient gel electrophoresis (DGGE) are frequently used in various fields of microbiology. The major difficulty in DNA fingerprinting data analysis is the alignment of multiple peak sets. We report here an R program for a clustering-based peak alignment algorithm, and its application to analyze various DNA fingerprinting data, such as ARDRA, rep-PCR, RISA, and DGGE data. The results obtained by our clustering algorithm and by BioNumerics software showed high similarity. Since several R packages have been established to statistically analyze various biological data, the distance matrix obtained by our R program can be used for subsequent statistical analyses, some of which were not previously performed but are useful in DNA fingerprinting studies.

  12. Exact method for numerically analyzing a model of local denaturation in superhelically stressed DNA

    International Nuclear Information System (INIS)

    Fye, R.M.; Benham, C.J.

    1999-01-01

    Local denaturation, the separation at specific sites of the two strands comprising the DNA double helix, is one of the most fundamental processes in biology, required to allow the base sequence to be read both in DNA transcription and in replication. In living organisms this process can be mediated by enzymes which regulate the amount of superhelical stress imposed on the DNA. We present a numerically exact technique for analyzing a model of denaturation in superhelically stressed DNA. This approach is capable of predicting the locations and extents of transition in circular superhelical DNA molecules of kilobase lengths and specified base pair sequences. It can also be used for closed loops of DNA which are typically found in vivo to be kilobases long. The analytic method consists of an integration over the DNA twist degrees of freedom followed by the introduction of auxiliary variables to decouple the remaining degrees of freedom, which allows the use of the transfer matrix method. The algorithm implementing our technique requires O(N 2 ) operations and O(N) memory to analyze a DNA domain containing N base pairs. However, to analyze kilobase length DNA molecules it must be implemented in high precision floating point arithmetic. An accelerated algorithm is constructed by imposing an upper bound M on the number of base pairs that can simultaneously denature in a state. This accelerated algorithm requires O(MN) operations, and has an analytically bounded error. Sample calculations show that it achieves high accuracy (greater than 15 decimal digits) with relatively small values of M (M<0.05N) for kilobase length molecules under physiologically relevant conditions. Calculations are performed on the superhelical pBR322 DNA sequence to test the accuracy of the method. With no free parameters in the model, the locations and extents of local denaturation predicted by this analysis are in quantitatively precise agreement with in vitro experimental measurements

  13. Radon-induced DNA damage and apoptosis analyzed by flow cytometry

    International Nuclear Information System (INIS)

    Meenakshi, C.; Mohankumar, Mary N.

    2012-01-01

    Natural radiation is the major source of human exposure to ionizing radiation and its largest contributing component to effective doses arises from inhalation of 222 Rn and its radioactive progeny. 222 Rn, a chemically inert gas produced naturally from radium in rocks and soil is a proven source of lung cancer especially in closed environments such as mines and in poorly ventilated homes. Much of the data on the effect of radon in humans comes from epidemiological studies, often masked by confounding factors such as age, smoking and lifestyle. Radiation carcinogenesis is initiated by DNA damage and flow cytometry is a versatile, fast and accurate technique for the analysis of DNA damage as it offers the analysis of high number of individual cells in few minutes. An attempt was made to detect DNA damage and apoptosis after exposing human blood cells in vitro to radon by flow cytometry. Blood samples were collected from apparently healthy individuals and exposed in vitro to radon ranging between 1-5 mGy using a simple, portable irradiation assembly designed and tested at the Radiological Safety Division of Indira Gandhi Centre for Atomic Research. Cultures were initiated by the addition of phytohemagglutinin and cells were processed stained and analyzed for DNA damage and apoptosis by flow cytometry. CV values indicative of DNA damage were plotted against dose and were observed to increase in a dose dependent manner 3h after of irradiation. However no such response was observed at 24h and 48h. Nevertheless, the percentage of apoptotic cells increased steadily with dose after 24 and 48h post exposure. DNA breaks appear to be rejoined after about 24h of irradiation. However apoptotic cells increased with time and dose, suggesting elimination of highly damaged cells. Further experiments are needed to identify apoptotic cells as a biomarker of radiation exposure and risk. (author)

  14. How are base excision DNA repair pathways deployed in vivo? [version 1; referees: 4 approved

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    Upasna Thapar

    2017-03-01

    Full Text Available Since the discovery of the base excision repair (BER system for DNA more than 40 years ago, new branches of the pathway have been revealed at the biochemical level by in vitro studies. Largely for technical reasons, however, the confirmation of these subpathways in vivo has been elusive. We review methods that have been used to explore BER in mammalian cells, indicate where there are important knowledge gaps to fill, and suggest a way to address them.

  15. A set of primers for analyzing chloroplast DNA diversity in Citrus and related genera.

    Science.gov (United States)

    Cheng, Yunjiang; de Vicente, M Carmen; Meng, Haijun; Guo, Wenwu; Tao, Nengguo; Deng, Xiuxin

    2005-06-01

    Chloroplast simple sequence repeat (cpSSR) markers in Citrus were developed and used to analyze chloroplast diversity of Citrus and closely related genera. Fourteen cpSSR primer pairs from the chloroplast genomes of tobacco (Nicotiana tabacum L.) and Arabidopsis were found useful for analyzing the Citrus chloroplast genome (cpDNA) and recoded with the prefix SPCC (SSR Primers for Citrus Chloroplast). Eleven of the 14 primer pairs revealed some degree of polymorphism among 34 genotypes of Citrus, Fortunella, Poncirus and some of their hybrids, with polymorphism information content (PIC) values ranging from 0.057 to 0.732, and 18 haplotypes were identified. The cpSSR data were analyzed with NTSYS-pc software, and the genetic relationships suggested by the unweighted pair group method based on arithmetic means (UPGMA) dendrogram were congruent with previous taxonomic investigations: the results showed that all samples fell into seven major clusters, i.e., Citrus medica L., Poncirus, Fortunella, C. ichangensis Blanco, C. reticulata Swingle, C. aurantifolia (Christm.) Swingle and C. grandis (L.) Osbeck. The results of previous studies combined with our cpSSR analyses revealed that: (1) Calamondin (C. madurensis Swingle) is the result of hybridization between kumquat (Fortunella) and mandarin (C. reticulata), where kumquat acted as the female parent; (2) Ichang papeda (C. ichangensis) has a unique taxonomic status; and (3) although Bendiguangju mandarin (C. reticulata) and Satsuma mandarin (C. reticulata) are similar in fruit shape and leaf morphology, they have different maternal parents. Bendiguangju mandarin has the same cytoplasm as sweet orange (C. sinensis), whereas Satsuma mandarin has the cytoplasm of C. reticulata. Seventeen PCR products from SPCC1 and 21 from SPCC11 were cloned and sequenced. The results revealed that mononucleotide repeats as well as insertions and deletions of small segments of DNA were associated with SPCC1 polymorphism, whereas polymorphism

  16. Computational method and system for modeling, analyzing, and optimizing DNA amplification and synthesis

    Science.gov (United States)

    Vandersall, Jennifer A.; Gardner, Shea N.; Clague, David S.

    2010-05-04

    A computational method and computer-based system of modeling DNA synthesis for the design and interpretation of PCR amplification, parallel DNA synthesis, and microarray chip analysis. The method and system include modules that address the bioinformatics, kinetics, and thermodynamics of DNA amplification and synthesis. Specifically, the steps of DNA selection, as well as the kinetics and thermodynamics of DNA hybridization and extensions, are addressed, which enable the optimization of the processing and the prediction of the products as a function of DNA sequence, mixing protocol, time, temperature and concentration of species.

  17. Analyzing The Impacts of the Biogas-to-Electricity Purchase Incentives on Electric Vehicle Deployment with the MA3T Vehicle Choice Model

    Energy Technology Data Exchange (ETDEWEB)

    Podkaminer, Kara [U.S. Department of Energy (DOE); Xie, Fei [ORNL; Lin, Zhenhong [ORNL

    2017-01-01

    scenario 2025 also represents the last year in which biogas-derived electricity is able to fully supply the transportation electricity demand in the model. After 2025, the credit value declines on a per vehicle basis. At the same time a larger fraction of the credit may shift towards biogas producers in order to incent additional biogas production. The expanded 41 TWh/year biogas availability scenarios represent an increase beyond today s generation capacity and allow greater eRIN generation. With a 5.24kWh/RIN equivalence value, when all of the credit is directed towards reducing vehicle purchase prices, the 41 TWh/year biogas scenario results in 4.1 million additional PHEVs and 12.2 million additional BEVs on the road in 2030 beyond the baseline of 2.5 million PHEVs and 6.1 million BEVs. Under this expanded biogas capacity, biogas-derived electricity generation is able to fully supply electricity for a fleet of over 21 million EVs (15.6 million BEVs and 5.8 million PHEVs) on a yearly basis. In addition to assessing the full value credit scenarios described above, multiple scenarios were analyzed to determine the impact if only a fraction of the credit value was passed on to the consumer. In all of these cases, the EV deployment was scaled back as the fraction of the credit that was passed on to the consumer was reduced. These scenarios can be used to estimate the impact if the credit value is reduced in other ways as well, as demonstrated by the scenarios where the current (22.6 kWh/RIN) equivalence value was used. The EV deployment that results from an equivalence value of 22.6 kWh/RIN equivalence value is roughly equivalent to the EV deployment observed in the 25% case using the 5.24 kWh/RIN equivalence value. A higher equivalence value means that a smaller number of credits, and therefore value, is created for each kWh, and therefore the impact on EV deployment is reduced. This analysis shows several of the drivers that will impact eRIN generation and credit value

  18. Mixed Sequence Reader: A Program for Analyzing DNA Sequences with Heterozygous Base Calling

    Science.gov (United States)

    Chang, Chun-Tien; Tsai, Chi-Neu; Tang, Chuan Yi; Chen, Chun-Houh; Lian, Jang-Hau; Hu, Chi-Yu; Tsai, Chia-Lung; Chao, Angel; Lai, Chyong-Huey; Wang, Tzu-Hao; Lee, Yun-Shien

    2012-01-01

    The direct sequencing of PCR products generates heterozygous base-calling fluorescence chromatograms that are useful for identifying single-nucleotide polymorphisms (SNPs), insertion-deletions (indels), short tandem repeats (STRs), and paralogous genes. Indels and STRs can be easily detected using the currently available Indelligent or ShiftDetector programs, which do not search reference sequences. However, the detection of other genomic variants remains a challenge due to the lack of appropriate tools for heterozygous base-calling fluorescence chromatogram data analysis. In this study, we developed a free web-based program, Mixed Sequence Reader (MSR), which can directly analyze heterozygous base-calling fluorescence chromatogram data in .abi file format using comparisons with reference sequences. The heterozygous sequences are identified as two distinct sequences and aligned with reference sequences. Our results showed that MSR may be used to (i) physically locate indel and STR sequences and determine STR copy number by searching NCBI reference sequences; (ii) predict combinations of microsatellite patterns using the Federal Bureau of Investigation Combined DNA Index System (CODIS); (iii) determine human papilloma virus (HPV) genotypes by searching current viral databases in cases of double infections; (iv) estimate the copy number of paralogous genes, such as β-defensin 4 (DEFB4) and its paralog HSPDP3. PMID:22778697

  19. Radiation-induced XRCC4 association with chromatin DNA analyzed by biochemical fractionation

    International Nuclear Information System (INIS)

    Kamdar, R.P.; Matsumoto, Yoshihisa

    2010-01-01

    XRCC4, in association with DNA ligase IV, is thought to play a critical role in the ligation of two DNA ends in DNA double-strand break (DSB) repair through non-homologous end-joining (NHEJ) pathway. In the present study, we captured radiation-induced chromatin-recruitment of XRCC4 by biochemical fractionation using detergent Nonidet P-40. A subpopulation of XRCC4 changed into a form that is resistant to the extraction with 0.5% Nonidet P-40-containing buffer after irradiation. This form of XRCC4 was liberated by micrococcal nuclease treatment, indicating that it had been tethered to chromatin DNA. This chromatin-recruitment of XRCC4 could be seen immediately (<0.1 hr) after irradiation and remained up to 4 hr after 20 Gy irradiation. It was seen even after irradiation of small doses, id est (i.e.), 2 Gy, but the residence of XRCC4 on chromatin was very transient after 2 Gy irradiation, returning to near normal level in 0.2-0.5 hr after irradiation. The chromatin-bound XRCC4 represented only -1% of total XRCC4 molecules even after 20 Gy irradiation and the quantitative analysis using purified protein as the reference suggested that only a few XRCC4-DNA ligase IV complexes were recruited to each DNA end. We further show that the chromatin-recruitment of XRCC4 was not attenuated by wortmannin, an inhibitor of DNA-PK, or siRNA-mediated knockdown of the DNA-PK catalytic subunit (DNA-PKcs), indicating that this process does not require DNA-PKcs. These results would provide us with useful experimental tools and important insights to understand the DNA repair process through NHEJ pathway. (author)

  20. diffloop: a computational framework for identifying and analyzing differential DNA loops from sequencing data.

    Science.gov (United States)

    Lareau, Caleb A; Aryee, Martin J; Berger, Bonnie

    2018-02-15

    The 3D architecture of DNA within the nucleus is a key determinant of interactions between genes, regulatory elements, and transcriptional machinery. As a result, differences in DNA looping structure are associated with variation in gene expression and cell state. To systematically assess changes in DNA looping architecture between samples, we introduce diffloop, an R/Bioconductor package that provides a suite of functions for the quality control, statistical testing, annotation, and visualization of DNA loops. We demonstrate this functionality by detecting differences between ENCODE ChIA-PET samples and relate looping to variability in epigenetic state. Diffloop is implemented as an R/Bioconductor package available at https://bioconductor.org/packages/release/bioc/html/diffloop.html. aryee.martin@mgh.harvard.edu. Supplementary data are available at Bioinformatics online. © The Author (2017). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com

  1. On-bead fluorescent DNA nanoprobes to analyze base excision repair activities

    Energy Technology Data Exchange (ETDEWEB)

    Gines, Guillaume; Saint-Pierre, Christine; Gasparutto, Didier, E-mail: didier.gasparutto@cea.fr

    2014-02-17

    Graphical abstract: -- Highlights: •On magnetic beads fluorescent enzymatic assays. •Simple, easy, non-radioactive and electrophoresis-free functional assay. •Lesion-containing hairpin DNA probes are selective for repair enzymes. •The biosensing platform allows the measurement of DNA repair activities from purified enzymes or within cell free extracts. -- Abstract: DNA integrity is constantly threatened by endogenous and exogenous agents that can modify its physical and chemical structure. Changes in DNA sequence can cause mutations sparked by some genetic diseases or cancers. Organisms have developed efficient defense mechanisms able to specifically repair each kind of lesion (alkylation, oxidation, single or double strand break, mismatch, etc). Here we report the adjustment of an original assay to detect enzymes’ activity of base excision repair (BER), that supports a set of lesions including abasic sites, alkylation, oxidation or deamination products of bases. The biosensor is characterized by a set of fluorescent hairpin-shaped nucleic acid probes supported on magnetic beads, each containing a selective lesion targeting a specific BER enzyme. We have studied the DNA glycosylase alkyl-adenine glycosylase (AAG) and the human AP-endonuclease (APE1) by incorporating within the DNA probe a hypoxanthine lesion or an abasic site analog (tetrahydrofuran), respectively. Enzymatic repair activity induces the formation of a nick in the damaged strand, leading to probe's break, that is detected in the supernatant by fluorescence. The functional assay allows the measurement of DNA repair activities from purified enzymes or in cell-free extracts in a fast, specific, quantitative and sensitive way, using only 1 pmol of probe for a test. We recorded a detection limit of 1 μg mL{sup −1} and 50 μg mL{sup −1} of HeLa nuclear extracts for APE1 and AAG enzymes, respectively. Finally, the on-bead assay should be useful to screen inhibitors of DNA repair

  2. On-bead fluorescent DNA nanoprobes to analyze base excision repair activities

    International Nuclear Information System (INIS)

    Gines, Guillaume; Saint-Pierre, Christine; Gasparutto, Didier

    2014-01-01

    Graphical abstract: -- Highlights: •On magnetic beads fluorescent enzymatic assays. •Simple, easy, non-radioactive and electrophoresis-free functional assay. •Lesion-containing hairpin DNA probes are selective for repair enzymes. •The biosensing platform allows the measurement of DNA repair activities from purified enzymes or within cell free extracts. -- Abstract: DNA integrity is constantly threatened by endogenous and exogenous agents that can modify its physical and chemical structure. Changes in DNA sequence can cause mutations sparked by some genetic diseases or cancers. Organisms have developed efficient defense mechanisms able to specifically repair each kind of lesion (alkylation, oxidation, single or double strand break, mismatch, etc). Here we report the adjustment of an original assay to detect enzymes’ activity of base excision repair (BER), that supports a set of lesions including abasic sites, alkylation, oxidation or deamination products of bases. The biosensor is characterized by a set of fluorescent hairpin-shaped nucleic acid probes supported on magnetic beads, each containing a selective lesion targeting a specific BER enzyme. We have studied the DNA glycosylase alkyl-adenine glycosylase (AAG) and the human AP-endonuclease (APE1) by incorporating within the DNA probe a hypoxanthine lesion or an abasic site analog (tetrahydrofuran), respectively. Enzymatic repair activity induces the formation of a nick in the damaged strand, leading to probe's break, that is detected in the supernatant by fluorescence. The functional assay allows the measurement of DNA repair activities from purified enzymes or in cell-free extracts in a fast, specific, quantitative and sensitive way, using only 1 pmol of probe for a test. We recorded a detection limit of 1 μg mL −1 and 50 μg mL −1 of HeLa nuclear extracts for APE1 and AAG enzymes, respectively. Finally, the on-bead assay should be useful to screen inhibitors of DNA repair activities

  3. CloudDOE: a user-friendly tool for deploying Hadoop clouds and analyzing high-throughput sequencing data with MapReduce.

    Science.gov (United States)

    Chung, Wei-Chun; Chen, Chien-Chih; Ho, Jan-Ming; Lin, Chung-Yen; Hsu, Wen-Lian; Wang, Yu-Chun; Lee, D T; Lai, Feipei; Huang, Chih-Wei; Chang, Yu-Jung

    2014-01-01

    Explosive growth of next-generation sequencing data has resulted in ultra-large-scale data sets and ensuing computational problems. Cloud computing provides an on-demand and scalable environment for large-scale data analysis. Using a MapReduce framework, data and workload can be distributed via a network to computers in the cloud to substantially reduce computational latency. Hadoop/MapReduce has been successfully adopted in bioinformatics for genome assembly, mapping reads to genomes, and finding single nucleotide polymorphisms. Major cloud providers offer Hadoop cloud services to their users. However, it remains technically challenging to deploy a Hadoop cloud for those who prefer to run MapReduce programs in a cluster without built-in Hadoop/MapReduce. We present CloudDOE, a platform-independent software package implemented in Java. CloudDOE encapsulates technical details behind a user-friendly graphical interface, thus liberating scientists from having to perform complicated operational procedures. Users are guided through the user interface to deploy a Hadoop cloud within in-house computing environments and to run applications specifically targeted for bioinformatics, including CloudBurst, CloudBrush, and CloudRS. One may also use CloudDOE on top of a public cloud. CloudDOE consists of three wizards, i.e., Deploy, Operate, and Extend wizards. Deploy wizard is designed to aid the system administrator to deploy a Hadoop cloud. It installs Java runtime environment version 1.6 and Hadoop version 0.20.203, and initiates the service automatically. Operate wizard allows the user to run a MapReduce application on the dashboard list. To extend the dashboard list, the administrator may install a new MapReduce application using Extend wizard. CloudDOE is a user-friendly tool for deploying a Hadoop cloud. Its smart wizards substantially reduce the complexity and costs of deployment, execution, enhancement, and management. Interested users may collaborate to improve the

  4. CloudDOE: a user-friendly tool for deploying Hadoop clouds and analyzing high-throughput sequencing data with MapReduce.

    Directory of Open Access Journals (Sweden)

    Wei-Chun Chung

    Full Text Available Explosive growth of next-generation sequencing data has resulted in ultra-large-scale data sets and ensuing computational problems. Cloud computing provides an on-demand and scalable environment for large-scale data analysis. Using a MapReduce framework, data and workload can be distributed via a network to computers in the cloud to substantially reduce computational latency. Hadoop/MapReduce has been successfully adopted in bioinformatics for genome assembly, mapping reads to genomes, and finding single nucleotide polymorphisms. Major cloud providers offer Hadoop cloud services to their users. However, it remains technically challenging to deploy a Hadoop cloud for those who prefer to run MapReduce programs in a cluster without built-in Hadoop/MapReduce.We present CloudDOE, a platform-independent software package implemented in Java. CloudDOE encapsulates technical details behind a user-friendly graphical interface, thus liberating scientists from having to perform complicated operational procedures. Users are guided through the user interface to deploy a Hadoop cloud within in-house computing environments and to run applications specifically targeted for bioinformatics, including CloudBurst, CloudBrush, and CloudRS. One may also use CloudDOE on top of a public cloud. CloudDOE consists of three wizards, i.e., Deploy, Operate, and Extend wizards. Deploy wizard is designed to aid the system administrator to deploy a Hadoop cloud. It installs Java runtime environment version 1.6 and Hadoop version 0.20.203, and initiates the service automatically. Operate wizard allows the user to run a MapReduce application on the dashboard list. To extend the dashboard list, the administrator may install a new MapReduce application using Extend wizard.CloudDOE is a user-friendly tool for deploying a Hadoop cloud. Its smart wizards substantially reduce the complexity and costs of deployment, execution, enhancement, and management. Interested users may collaborate

  5. Geminin deploys multiple mechanisms to regulate Cdt1 before cell division thus ensuring the proper execution of DNA replication

    DEFF Research Database (Denmark)

    Ballabeni, Andrea; Zamponi, Raffaella; Moore, Jodene K

    2013-01-01

    the accumulation of Cdt1 in mitosis, because decreasing the Geminin levels prevents Cdt1 accumulation and impairs DNA replication. Geminin is known to inhibit Cdt1 function; its depletion during G2 leads to DNA rereplication and checkpoint activation. Here we show that, despite rapid Cdt1 protein turnover in G2...

  6. Analyzing the Impacts of a Biogas-to-Electricity Purchase Incentive on Electric Vehicle Deployment with the MA3T Vehicle Choice Model

    Energy Technology Data Exchange (ETDEWEB)

    Podkaminer, Kara [US Department of Energy, Washington, DC (United States); Xie, Fei [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Lin, Zhenhong [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2017-01-01

    In 2014, the EPA approved a biogas-to-electricity pathway under the Renewable Fuel Standard (RFS). However, no specific applications for this pathway have been approved to date. This analysis helps understand the impact of the pathway by representing the biogas-to-electricity pathway as a point of purchase incentive and tests the impact of this incentive on EV deployment using a vehicle consumer choice model.

  7. A quantitative assessment of the Hadoop framework for analyzing massively parallel DNA sequencing data.

    Science.gov (United States)

    Siretskiy, Alexey; Sundqvist, Tore; Voznesenskiy, Mikhail; Spjuth, Ola

    2015-01-01

    New high-throughput technologies, such as massively parallel sequencing, have transformed the life sciences into a data-intensive field. The most common e-infrastructure for analyzing this data consists of batch systems that are based on high-performance computing resources; however, the bioinformatics software that is built on this platform does not scale well in the general case. Recently, the Hadoop platform has emerged as an interesting option to address the challenges of increasingly large datasets with distributed storage, distributed processing, built-in data locality, fault tolerance, and an appealing programming methodology. In this work we introduce metrics and report on a quantitative comparison between Hadoop and a single node of conventional high-performance computing resources for the tasks of short read mapping and variant calling. We calculate efficiency as a function of data size and observe that the Hadoop platform is more efficient for biologically relevant data sizes in terms of computing hours for both split and un-split data files. We also quantify the advantages of the data locality provided by Hadoop for NGS problems, and show that a classical architecture with network-attached storage will not scale when computing resources increase in numbers. Measurements were performed using ten datasets of different sizes, up to 100 gigabases, using the pipeline implemented in Crossbow. To make a fair comparison, we implemented an improved preprocessor for Hadoop with better performance for splittable data files. For improved usability, we implemented a graphical user interface for Crossbow in a private cloud environment using the CloudGene platform. All of the code and data in this study are freely available as open source in public repositories. From our experiments we can conclude that the improved Hadoop pipeline scales better than the same pipeline on high-performance computing resources, we also conclude that Hadoop is an economically viable

  8. Deployment Repeatability

    Science.gov (United States)

    2016-04-01

    evaluating the deployment repeatability builds upon the testing or analysis of deployment kinematics (Chapter 6) and adds repetition. Introduction...material yield or failure during a test. For the purposes of this chapter, zero shift will refer to permanent changes in the structure, while reversible ...the content of other chapters in this book: Gravity Compensation (Chapter 4) and Deployment Kinematics and Dynamics (Chapter 6). Repeating the

  9. [Real-time quantification to analyze historical Colombian samples detecting a short fragment of hypervariable region II of mitochondrial DNA].

    Science.gov (United States)

    Pérez, Luz Adriana; Rodríguez, Freddy; Langebaek, Carl Henrik; Groot, Helena

    2016-09-01

    Unlike other molecular biology studies, the analysis of ancient DNA (aDNA) requires special infrastructure and methodological conditions to guarantee the quality of the results. One of the main authenticity criteria is DNA quantification, where quantitative real-time PCR is often used given its sensitivity and specificity. Nevertheless, the implementation of these conditions and methodologies to fulfill authenticity criteria imply higher costs. Objective: To develop a simple and less costly method for mitochondrial DNA quantification suitable for highly degraded samples. Materials and methods: The proposed method is based on the use of mini-primers for the specific amplification of short fragments of mitochondrial DNA. The subsequent purification of these amplified fragments allows a standard curve to be constructed with concentrations in accordance to the state of degradation of the samples. Results: The proposed method successfully detected DNA from ancient samples including bone remains and mummified tissue. DNA inhibitory substances were also detected. Conclusion: The proposed method represents a simpler and cost-effective way to detect low amounts of aDNA, and a tool to differentiate DNA-free samples from samples with inhibitory substances.

  10. Development and validation of a multiplex reaction analyzing eight miniSTRs of the X chromosome for identity and kinship testing with degraded DNA.

    Science.gov (United States)

    Castañeda, María; Odriozola, Adrián; Gómez, Javier; Zarrabeitia, María T

    2013-07-01

    We report the development of an effective system for analyzing X chromosome-linked mini short tandem repeat loci with reduced-size amplicons (less than 220 bp), useful for analyzing highly degraded DNA samples. To generate smaller amplicons, we redesigned primers for eight X-linked microsatellites (DXS7132, DXS10079, DXS10074, DXS10075, DXS6801, DXS6809, DXS6789, and DXS6799) and established efficient conditions for a multiplex PCR system (miniX). The validation tests confirmed that it has good sensitivity, requiring as little as 20 pg of DNA, and performs well with DNA from paraffin-embedded tissues, thus showing potential for improved analysis and identification of highly degraded and/or very limited DNA samples. Consequently, this system may help to solve complex forensic cases, particularly when autosomal markers convey insufficient information.

  11. Beyond repair foci: DNA double-strand break repair in euchromatic and heterochromatic compartments analyzed by transmission electron microscopy.

    Directory of Open Access Journals (Sweden)

    Yvonne Lorat

    Full Text Available DNA double-strand breaks (DSBs generated by ionizing radiation pose a serious threat to the preservation of genetic and epigenetic information. The known importance of local chromatin configuration in DSB repair raises the question of whether breaks in different chromatin environments are recognized and repaired by the same repair machinery and with similar efficiency. An essential step in DSB processing by non-homologous end joining is the high-affinity binding of Ku70-Ku80 and DNA-PKcs to double-stranded DNA ends that holds the ends in physical proximity for subsequent repair.Using transmission electron microscopy to localize gold-labeled pKu70 and pDNA-PKcs within nuclear ultrastructure, we monitored the formation and repair of actual DSBs within euchromatin (electron-lucent and heterochromatin (electron-dense in cortical neurons of irradiated mouse brain.While DNA lesions in euchromatin (characterized by two pKu70-gold beads, reflecting the Ku70-Ku80 heterodimer are promptly sensed and rejoined, DNA packaging in heterochromatin appears to retard DSB processing, due to the time needed to unravel higher-order chromatin structures. Complex pKu70-clusters formed in heterochromatin (consisting of 4 or ≥ 6 gold beads may represent multiple breaks in close proximity caused by ionizing radiation of highly-compacted DNA. All pKu70-clusters disappeared within 72 hours post-irradiation, indicating efficient DSB rejoining. However, persistent 53BP1 clusters in heterochromatin (comprising ≥ 10 gold beads, occasionally co-localizing with γH2AX, but not pKu70 or pDNA-PKcs, may reflect incomplete or incorrect restoration of chromatin structure rather than persistently unrepaired DNA damage.Higher-order organization of chromatin determines the accessibility of DNA lesions to repair complexes, defining how readily DSBs are detected and processed. DNA lesions in heterochromatin appear to be more complex, with multiple breaks in spatial vicinity inducing

  12. Deployment Repeatability

    Science.gov (United States)

    2016-08-31

    large cohort of trials to spot unusual cases. However, deployment repeatability is inherently a nonlinear phenomenon, which makes modeling difficult...and GEMS tip position were both tracked during ground testing by a laser target tracking system. Earlier SAILMAST testing in 2005 [8] used...recalls the strategy used by SRTM, where a constellation of lights was installed at the tip of the boom and a modified star tracker was used to track tip

  13. Performance of Identifiler Direct and PowerPlex 16 HS on the Applied Biosystems 3730 DNA Analyzer for processing biological samples archived on FTA cards.

    Science.gov (United States)

    Laurin, Nancy; DeMoors, Anick; Frégeau, Chantal

    2012-09-01

    Direct amplification of STR loci from biological samples collected on FTA cards without prior DNA purification was evaluated using Identifiler Direct and PowerPlex 16 HS in conjunction with the use of a high throughput Applied Biosystems 3730 DNA Analyzer. In order to reduce the overall sample processing cost, reduced PCR volumes combined with various FTA disk sizes were tested. Optimized STR profiles were obtained using a 0.53 mm disk size in 10 μL PCR volume for both STR systems. These protocols proved effective in generating high quality profiles on the 3730 DNA Analyzer from both blood and buccal FTA samples. Reproducibility, concordance, robustness, sample stability and profile quality were assessed using a collection of blood and buccal samples on FTA cards from volunteer donors as well as from convicted offenders. The new developed protocols offer enhanced throughput capability and cost effectiveness without compromising the robustness and quality of the STR profiles obtained. These results support the use of these protocols for processing convicted offender samples submitted to the National DNA Data Bank of Canada. Similar protocols could be applied to the processing of casework reference samples or in paternity or family relationship testing. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  14. Predicting and analyzing DNA-binding domains using a systematic approach to identifying a set of informative physicochemical and biochemical properties

    Science.gov (United States)

    2011-01-01

    Background Existing methods of predicting DNA-binding proteins used valuable features of physicochemical properties to design support vector machine (SVM) based classifiers. Generally, selection of physicochemical properties and determination of their corresponding feature vectors rely mainly on known properties of binding mechanism and experience of designers. However, there exists a troublesome problem for designers that some different physicochemical properties have similar vectors of representing 20 amino acids and some closely related physicochemical properties have dissimilar vectors. Results This study proposes a systematic approach (named Auto-IDPCPs) to automatically identify a set of physicochemical and biochemical properties in the AAindex database to design SVM-based classifiers for predicting and analyzing DNA-binding domains/proteins. Auto-IDPCPs consists of 1) clustering 531 amino acid indices in AAindex into 20 clusters using a fuzzy c-means algorithm, 2) utilizing an efficient genetic algorithm based optimization method IBCGA to select an informative feature set of size m to represent sequences, and 3) analyzing the selected features to identify related physicochemical properties which may affect the binding mechanism of DNA-binding domains/proteins. The proposed Auto-IDPCPs identified m=22 features of properties belonging to five clusters for predicting DNA-binding domains with a five-fold cross-validation accuracy of 87.12%, which is promising compared with the accuracy of 86.62% of the existing method PSSM-400. For predicting DNA-binding sequences, the accuracy of 75.50% was obtained using m=28 features, where PSSM-400 has an accuracy of 74.22%. Auto-IDPCPs and PSSM-400 have accuracies of 80.73% and 82.81%, respectively, applied to an independent test data set of DNA-binding domains. Some typical physicochemical properties discovered are hydrophobicity, secondary structure, charge, solvent accessibility, polarity, flexibility, normalized Van Der

  15. Quality function deployment

    International Nuclear Information System (INIS)

    1981-10-01

    This book indicates quality function deployment with quality and deployment of quality function, process and prospect of quality function deployment and development, product process and conception of quality table, deployment of quality demand, design of quality table and application of concurrent multi design, progress design and quality development, main safe part and management of important function part, quality development and deployment of method of construction, quality deployment and economics, total system of quality function deployment and task of quality function deployment in the present and future.

  16. Solar sail deployment experiment

    OpenAIRE

    Shimose, Shigeru; 下瀬 滋

    2006-01-01

    Solar Sail move by receiving momentum of photons in sunlight. This paper presents results of some Spin-Stabilized Solar Sail deployment experiment. ISAS has successfully deployed, for the first time in the world, the polyimide Solar Sail taking advantage of centrifugal force in space. Based on this result, the new deployment mechanism is being developed which retracts the 50 m diameter sail.

  17. Mastering Windows 7 Deployment

    CERN Document Server

    Finn, Aidan; van Surksum, Kenneth

    2011-01-01

    Get professional-level instruction on Windows 7 deployment tools Enterprise-level operating system deployment is challenging and requires knowledge of specific tools. It is expected that Windows 7 will be extensively deployed in businesses worldwide. This comprehensive Sybex guide provides thorough coverage of the Microsoft deployment tools that were specifically created for Windows 7, preparing system administrators, MIS professionals, and corporate programmers to tackle the task effectively.Companies worldwide are expected to deploy Windows 7 as their enterprise operating system; system admi

  18. Tether Deployer And Brake

    Science.gov (United States)

    Carroll, Joseph A.; Alexander, Charles M.

    1993-01-01

    Design concept promises speed, control, and reliability. Scheme for deploying tether provides for fast, free, and snagless payout and fast, dependable braking. Developed for small, expendable tethers in outer space, scheme also useful in laying transoceanic cables, deploying guidance wires to torpedoes and missiles, paying out rescue lines from ship to ship via rockets, deploying antenna wires, releasing communication and power cables to sonobuoys and expendable bathythermographs, and in reeling out lines from fishing rods.

  19. RSOI: Force Deployment Bottleneck

    National Research Council Canada - National Science Library

    D'Amato, Mark

    1998-01-01

    This study uses The Theory Of Constraints (TOC) management methodology and recent military missions to show that RSOI operations are generally the limiting constraint to force deployment operations...

  20. Center for Deployment Psychology

    Data.gov (United States)

    Federal Laboratory Consortium — The Center for Deployment Psychology was developed to promote the education of psychologists and other behavioral health specialists about issues pertaining to the...

  1. Deployment Health Surveillance

    National Research Council Canada - National Science Library

    DeNicola, Anthony D

    2004-01-01

    .... Gulf War health questions have resulted in controversy over potentially hazardous exposures during the deployment, the possibility of adverse affects from preventive health measures, and the role...

  2. Oxidative stress and DNA damage caused by the urban air pollutant 3-NBA and its isomer 2-NBA in human lung cells analyzed with three independent methods.

    Science.gov (United States)

    Nagy, Eszter; Johansson, Clara; Zeisig, Magnus; Möller, Lennart

    2005-11-15

    The air pollutant 3-nitrobenzanthrone (3-NBA), emitted in diesel exhaust, is a potent mutagen and genotoxin. 3-NBA can isomerise to 2-nitrobenzanthrone (2-NBA), which can become more than 70-fold higher in concentration in ambient air. In this study, three independent methods have been employed to evaluate the oxidative stress and genotoxicity of 2-NBA compared to 3-NBA in the human A549 lung cell line. HPLC-EC/UV was applied for measurements of oxidative damage in the form of 8-oxo-2'-deoxyguanosine (8-oxodG), (32)P-HPLC for measurements of lipophilic DNA-adducts, and the Comet assay to measure a variety of DNA lesions, including oxidative stress. No significant oxidative damage from either isomer was found regarding formation of 8-oxodG analysed using HPLC-EC/UV. However, the Comet assay (with FPG-treatment), which is more sensitive and detects more types of damages compared to HPLC-EC/UV, showed a significant effect from both 3-NBA and 2-NBA. (32)P-HPLC revealed a strong DNA-adduct formation from both 3-NBA and 2-NBA, and also a significant difference between both isomers compared to negative control. These results clearly show that 2-NBA has a genotoxic potential. Even if the DNA-adduct forming capacity and the amount of DNA lesions measured with the (32)P-HPLC and Comet assay is about one third of 3-NBA, the high abundance of 2-NBA in ambient air calls for further investigation and evaluation of its health hazard.

  3. Modeling EERE Deployment Programs

    Energy Technology Data Exchange (ETDEWEB)

    Cort, K. A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Hostick, D. J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Belzer, D. B. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Livingston, O. V. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2007-11-01

    This report compiles information and conclusions gathered as part of the “Modeling EERE Deployment Programs” project. The purpose of the project was to identify and characterize the modeling of deployment programs within the EERE Technology Development (TD) programs, address possible improvements to the modeling process, and note gaps in knowledge in which future research is needed.

  4. Structural Effects of Some Relevant Missense Mutations on the MECP2-DNA Binding: A MD Study Analyzed by Rescore+, a Versatile Rescoring Tool of the VEGA ZZ Program.

    Science.gov (United States)

    Pedretti, Alessandro; Granito, Cinzia; Mazzolari, Angelica; Vistoli, Giulio

    2016-09-01

    DNA methylation plays key roles in mammalian cells and is modulated by a set of proteins which recognize symmetrically methylated nucleotides. Among them, the protein MECP2 shows multifunctional roles repressing and/or activating genes by binding to both methylated and unmethylated regions of the genome. The interest for this protein markedly increased from the observation that its mutations are the primary cause of Rett syndrome, a neurodevelopmental disorder which causes mental retardation in young females. Thus, the present study is aimed to investigate the effects of some of these known pathogenic missense mutations (i.e. R106Q, R106W, R111G, R133C and R133H) on the MECP2 folding and DNA binding by molecular dynamics simulations. The effects of the simulated mutations are also parameterized by using a here proposed new tool, named Rescore+, implemented in the VEGA ZZ suite of programs, which calculates a set of scoring functions on all frames of a trajectory or on all complexes contained in a database thus allowing an easy rescoring of results coming from MD or docking simulations. The obtained results revealed that the reported loss of the MECP2 function induced by the simulated mutations can be ascribed to both stabilizing and destabilizing effect on DNA binding. The study confirms that MD simulations are particularly useful to rationalize and predict the mutation effects offering insightful information for diagnostics and drug design. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  5. Part 8. Deployment considerations

    International Nuclear Information System (INIS)

    Dance, K.D.; Chang, Y.I.; Daly, T.A.

    1980-01-01

    This report addresses considerations of fast breeder reactor development and deployment from a national perspective. Nations vary greatly in their expertise and interest relative to nuclear power, and hence a single set of steps to be taken by a nation in decision-making on breeder development and deployment cannot be presented. The approach taken in this report is to present discussions on key factors influencing the breeder development and deployment decisions, especially in non-breeder nations, by drawing upon historical perspectives of the Light Water Reactor for comparison

  6. Deployment Health Surveillance

    National Research Council Canada - National Science Library

    DeNicola, Anthony D

    2004-01-01

    ... of stress in causing chronic illness. The lack of comprehensive deployment health surveillance has made it difficult to determine possible causes of adverse health effects reported by Gulf War veterans...

  7. Modeling EERE deployment programs

    Energy Technology Data Exchange (ETDEWEB)

    Cort, K. A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Hostick, D. J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Belzer, D. B. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Livingston, O. V. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2007-11-01

    The purpose of the project was to identify and characterize the modeling of deployment programs within the EERE Technology Development (TD) programs, address possible improvements to the modeling process, and note gaps in knowledge for future research.

  8. RSOI: Force Deployment Bottleneck

    National Research Council Canada - National Science Library

    D'Amato, Mark

    1998-01-01

    .... This runs counter to the popular belief that strategic lift is the limiting constraint. The study begins by highlighting the genesis of the military's current force projection strategy and the resulting importance of rapid force deployments...

  9. Droplet digital PCR combined with minisequencing, a new approach to analyze fetal DNA from maternal blood: application to the non-invasive prenatal diagnosis of achondroplasia.

    Science.gov (United States)

    Orhant, Lucie; Anselem, Olivia; Fradin, Mélanie; Becker, Pierre Hadrien; Beugnet, Caroline; Deburgrave, Nathalie; Tafuri, Gilles; Letourneur, Franck; Goffinet, François; Allach El Khattabi, Laïla; Leturcq, France; Bienvenu, Thierry; Tsatsaris, Vassilis; Nectoux, Juliette

    2016-05-01

    Achondroplasia is generally detected by abnormal prenatal ultrasound findings in the third trimester of pregnancy and then confirmed by molecular genetic testing of fetal genomic DNA obtained by aspiration of amniotic fluid. This invasive procedure presents a small but significant risk for both the fetus and mother. Therefore, non-invasive procedures using cell-free fetal DNA in maternal plasma have been developed for the detection of the fetal achondroplasia mutations. To determine whether the fetus carries the de novo mis-sense genetic mutation at nucleotide 1138 in FGFR3 gene involved in >99% of achondroplasia cases, we developed two independent methods: digital-droplet PCR combined with minisequencing, which are very sensitive methods allowing detection of rare alleles. We collected 26 plasmatic samples from women carrying fetus at risk of achondroplasia and diagnosed to date a total of five affected fetuses in maternal blood. The sensitivity and specificity of our test are respectively 100% [95% confidence interval, 56.6-100%] and 100% [95% confidence interval, 84.5-100%]. This novel, original strategy for non-invasive prenatal diagnosis of achondroplasia is suitable for implementation in routine clinical testing and allows considering extending the applications of these technologies in non-invasive prenatal diagnosis of many other monogenic diseases. © 2016 John Wiley & Sons, Ltd. © 2016 John Wiley & Sons, Ltd.

  10. Deployable Brake for Spacecraft

    Science.gov (United States)

    Rausch, J. R.; Maloney, J. W.

    1987-01-01

    Aerodynamic shield that could be opened and closed proposed. Report presents concepts for deployable aerodynamic brake. Brake used by spacecraft returning from high orbit to low orbit around Earth. Spacecraft makes grazing passes through atmosphere to slow down by drag of brake. Brake flexible shield made of woven metal or ceramic withstanding high temperatures created by air friction. Stored until needed, then deployed by set of struts.

  11. Transient analyzer

    International Nuclear Information System (INIS)

    Muir, M.D.

    1975-01-01

    The design and design philosophy of a high performance, extremely versatile transient analyzer is described. This sub-system was designed to be controlled through the data acquisition computer system which allows hands off operation. Thus it may be placed on the experiment side of the high voltage safety break between the experimental device and the control room. This analyzer provides control features which are extremely useful for data acquisition from PPPL diagnostics. These include dynamic sample rate changing, which may be intermixed with multiple post trigger operations with variable length blocks using normal, peak to peak or integrate modes. Included in the discussion are general remarks on the advantages of adding intelligence to transient analyzers, a detailed description of the characteristics of the PPPL transient analyzer, a description of the hardware, firmware, control language and operation of the PPPL transient analyzer, and general remarks on future trends in this type of instrumentation both at PPPL and in general

  12. Advanced OS deployment system

    OpenAIRE

    Galiano Molina, Sebastián

    2007-01-01

    The main project’s objective is to design and build an OS deployment system taking advantage of the Linux OS and the Open Source community developments. This means to use existing technologies that modularize the system. With this philosophy in mind, the number of developed code lines within the project is keeping as small as possible. As REMBO, the OS deployment system to develop has to be transparent to the user. This means a system with a friendly user interface and no te...

  13. Modeling EERE Deployment Programs

    Energy Technology Data Exchange (ETDEWEB)

    Cort, Katherine A.; Hostick, Donna J.; Belzer, David B.; Livingston, Olga V.

    2007-11-08

    The purpose of this report is to compile information and conclusions gathered as part of three separate tasks undertaken as part of the overall project, “Modeling EERE Deployment Programs,” sponsored by the Planning, Analysis, and Evaluation office within the Department of Energy’s Office of Energy Efficiency and Renewable Energy (EERE). The purpose of the project was to identify and characterize the modeling of deployment programs within the EERE Technology Development (TD) programs, address improvements to modeling in the near term, and note gaps in knowledge where future research is needed.

  14. Remote Systems Design & Deployment

    Energy Technology Data Exchange (ETDEWEB)

    Bailey, Sharon A.; Baker, Carl P.; Valdez, Patrick LJ

    2009-08-28

    The Pacific Northwest National Laboratory (PNNL) was tasked by Washington River Protection Solutions, LLC (WRPS) to provide information and lessons learned relating to the design, development and deployment of remote systems, particularly remote arm/manipulator systems. This report reflects PNNL’s experience with remote systems and lays out the most important activities that need to be completed to successfully design, build, deploy and operate remote systems in radioactive and chemically contaminated environments. It also contains lessons learned from PNNL’s work experiences, and the work of others in the national laboratory complex.

  15. Radiometric analyzer

    International Nuclear Information System (INIS)

    Arima, S.; Oda, M.; Miyashita, K.; Takada, M.

    1977-01-01

    A radiometric analyzer for measuring the characteristic values of a sample by radiation includes a humer of radiation measuring subsystems having different ratios of sensitivities to the elements of the sample and linearizing circuits having inverse function characteristics of calibration functions which correspond to the radiation measuring subsystems. A weighing adder operates a desirable linear combination of the outputs of the linearizing circuits. Operators for operating between two or more different linear combinations are included

  16. Deploying Node.js

    CERN Document Server

    Pasquali, Sandro

    2015-01-01

    If you are an intermediate or advanced developer deploying your Node.js applications, then this book is for you. If you have already built a Node application or module and want to take your knowledge to the next level, this book will help you find your way.

  17. Cooperative Technolgy Deployed

    NARCIS (Netherlands)

    Koenders, E.; Velt, R. in 't

    2011-01-01

    After the successful demonstrations of cooperative technology by the CVIS and Safespot projects the question remains how this technology can be successfully deployed. This question is explored by the Field Operational Test project FREILOT, which aims to provide fuel economy applications that must be

  18. Fusion Power Deployment

    International Nuclear Information System (INIS)

    Schmidt, J.A.; Ogden, J.M.

    2002-01-01

    Fusion power plants could be part of a future portfolio of non-carbon dioxide producing energy supplies such as wind, solar, biomass, advanced fission power, and fossil energy with carbon dioxide sequestration. In this paper, we discuss key issues that could impact fusion energy deployment during the last half of this century. These include geographic issues such as resource availability, scale issues, energy storage requirements, and waste issues. The resource needs and waste production associated with fusion deployment in the U.S. should not pose serious problems. One important feature of fusion power is the fact that a fusion power plant should be locatable within most local or regional electrical distribution systems. For this reason, fusion power plants should not increase the burden of long distance power transmission to our distribution system. In contrast to fusion power, regional factors could play an important role in the deployment of renewable resources such as wind, solar and biomass or fossil energy with CO2 sequestration. We examine the role of these regional factors and their implications for fusion power deployment

  19. Contamination Analyzer

    Science.gov (United States)

    1994-01-01

    Measurement of the total organic carbon content in water is important in assessing contamination levels in high purity water for power generation, pharmaceutical production and electronics manufacture. Even trace levels of organic compounds can cause defects in manufactured products. The Sievers Model 800 Total Organic Carbon (TOC) Analyzer, based on technology developed for the Space Station, uses a strong chemical oxidizing agent and ultraviolet light to convert organic compounds in water to carbon dioxide. After ionizing the carbon dioxide, the amount of ions is determined by measuring the conductivity of the deionized water. The new technique is highly sensitive, does not require compressed gas, and maintenance is minimal.

  20. Oligo-dT anchored cDNA-SCoT: a novel differential display method for analyzing differential gene expression in response to several stress treatments in mango (Mangifera indica L.).

    Science.gov (United States)

    Luo, Cong; He, Xin-Hua; Hu, Ying; Yu, Hai-xia; Ou, Shi-Jin; Fang, Zhong-Bin

    2014-09-15

    Differential display is a powerful technique for analyzing differences in gene expression. Oligo-dT cDNAstart codon targeted marker (cDNA-SCoT) technique is a novel, simple, cheap, rapid, and efficient method for differential gene expression research. In the present study, the oligo-dT anchored cDNA-SCoT technique was exploited to identify differentially expressed genes during several stress treatments in mango. A total of 37 primers combined with oligo-dT anchor primers 3side amplified approximately 150 fragments of 150 bp to 1500 bp in length. Up to 100 fragments were differentially expressed among the stress treatments and control samples, among which 92 were obtained and sequenced. Out of the 92 transcript derived fragments (TDFs), 70% were highly homologous to known genes, and 30% encoded unclassified proteins with unknown functions. The expression pattern of nine genes with known functions involved in several abiotic stresses in other species was confirmed by quantitative reverse transcription polymerase chain reaction (qRT-PCR) under cold (4 °C), salinity (NaCl), polyethylene glycol (PEG, MW 6000), and heavy metal treatments in leaves and stems at different time points (0, 24, 48, and 72 h). The expression patterns of the genes (TDF4, TDF7, TDF23, TDF45, TDF49, TDF50, TDF57, TDF91 and TDF92) that had direct or indirect relationships with cold, salinity, drought and heavy metal stress response were analyzed through qRT-PCR. The possible roles of these genes are discussed. This study suggests that the oligo-dT anchored cDNA-SCoT differential display method is a useful tool to serve as an initial step for characterizing transcriptional changes induced by abiotic stresses and provide gene information for further study and application in genetic improvement and breeding in mango. Copyright © 2014 Elsevier B.V. All rights reserved.

  1. Large Deployable Reflector (LDR)

    Science.gov (United States)

    Alff, W. H.

    1980-01-01

    The feasibility and costs were determined for a 1 m to 30 m diameter ambient temperature, infrared to submillimeter orbiting astronomical telescope which is to be shuttle-deployed, free-flying, and have a 10 year orbital life. Baseline concepts, constraints on delivery and deployment, and the sunshield required are examined. Reflector concepts, the optical configuration, alignment and pointing, and materials are also discussed. Technology studies show that a 10 m to 30 m diameter system which is background and diffraction limited at 30 micron m is feasible within the stated time frame. A 10 m system is feasible with current mirror technology, while a 30 m system requires technology still in development.

  2. Deployable reflector configurations

    Science.gov (United States)

    Meinel, A. B.; Meinel, M. P.; Woolf, N. J.

    Both the theoretical reasons for considering a non-circular format for the Large Deployable Reflector, and a potentially realizable concept for such a device, are discussed. The optimum systems for diffraction limited telescopes with incoherent detection have either a single filled aperture, or two such apertures as an interferometer to synthesize a larger aperture. For a single aperture of limited area, a reflector in the form of a slot can be used to give increased angular resolution. It is shown how a 20 x 8 meter telescope can be configured to fit the Space Shuttle bay, and deployed with relatively simple operations. The relationship between the sunshield design and the inclination of the orbit is discussed. The possible use of the LDR as a basic module to permit the construction of supergiant space telescopes and interferometers both for IR/submm studies and for the entire ultraviolet through mm wave spectral region is discussed.

  3. Treatment Deployment Evaluation Tool

    International Nuclear Information System (INIS)

    M. A. Rynearson; M. M. Plum

    1999-01-01

    The U.S. Department of Energy (DOE) is responsible for the final disposition of legacy spent nuclear fuel (SNF). As a response, DOE's National Spent Nuclear Fuel Program (NSNFP) has been given the responsibility for the disposition of DOE-owned SNF. Many treatment technologies have been identified to treat some forms of SNF so that the resulting treated product is acceptable by the disposition site. One of these promising treatment processes is the electrometallurgical treatment (EMT) currently in development; a second is an Acid Wash Decladding process. The NSNFP has been tasked with identifying possible strategies for the deployment of these treatment processes in the event that a treatment path is deemed necessary. To support the siting studies of these strategies, economic evaluations are being performed to identify the least-cost deployment path. This model (tool) was developed to consider the full scope of costs, technical feasibility, process material disposition, and schedule attributes over the life of each deployment alternative. Using standard personal computer (PC) software, the model was developed as a comprehensive technology economic assessment tool using a Life-Cycle Cost (LCC) analysis methodology. Model development was planned as a systematic, iterative process of identifying and bounding the required activities to dispose of SNF. To support the evaluation process, activities are decomposed into lower level, easier to estimate activities. Sensitivity studies can then be performed on these activities, defining cost issues and testing results against the originally stated problem

  4. Logistics analysis to Improve Deployability (LOG-AID): Field Experiment/Results

    National Research Council Canada - National Science Library

    Evers, Kenneth

    2000-01-01

    .... Under sponsorship of the Air Force Research Laboratory Logistics Readiness Branch (AFRL/HESR), the Synergy team analyzed the current wing-level deployment process as part of the Logistics Analysis to Improve Deployability (LOG-AID) program...

  5. Economics of ALMR deployment

    International Nuclear Information System (INIS)

    Delene, J.G.; Fuller, L.C.; Hudson, C.R.

    1994-01-01

    The Advanced Liquid Metal Reactor (ALMR) has the potential to extend the economic life of the nuclear option and of reducing the number of high level waste repositories which will eventually be needed in an expanding nuclear economy. This paper reports on an analysis which models and evaluates the economics of the use of ALMRs as a component of this country's future electricity generation mix. The ALMR concept has the ability to utilize as fuel the fissile material contained in previously irradiated nuclear fuel (i.e., spent fuel) or from surplus weapons grade material. While not a requirement for the successful deployment of ALMR power plant technology, the reprocessing of spent fuel from light water reactors (LWR) is necessary for any rapid introduction of ALMR power plants. In addition, the reprocessing of LWR spent fuel may reduce the number of high level waste repositories needed in the future by burning the long-lived actinides produced in the fission process. With this study, the relative economics of a number of potential scenarios related to these issues are evaluated. While not encompassing the full range of all possibilities, the cases reported here provide an indication of the potential costs, timings, and relative economic attractiveness of ALMR deployment

  6. ALMR deployment economic analysis

    International Nuclear Information System (INIS)

    Delene, J.G.; Fuller, L.C.; Hudson, C.R.

    1993-06-01

    This analysis seeks to model and evaluate the economics of the use of Advanced Liquid Metal Reactors (ALMR) as a component of this country's future electricity generation mix. The ALMR concept has the ability to utilize as fuel the fissile material contained in previously irradiated nuclear fuel (i.e., spent fuel). While not a requirement for the successful deployment of ALMR power plant technology, the reprocessing of spent fuel from light water reactors (LWR) is necessary for any rapid introduction of ALMR power plants. In addition, the reprocessing of LWR spent fuel may reduce the number of high level waste repositories needed in the future by burning the long-lived actinides produced in the fission process. With this study, the relative economics of a number of potential scenarios related to these issues are evaluated. While not encompassing the full range of all possibilities, the cases reported here provide an indication of the potential costs, timings, and relative economic attractiveness of ALMR deployment

  7. University of Tennessee deploys force10 switch for CERN work

    CERN Multimedia

    2007-01-01

    "Force20 networks, the pioneer in building and securing reliable networks, today announced that the University of Tennessee physics department has deployed the C300 resilient switch to analyze data form CERN's Large Hadron Collider." (1/2 page)

  8. Complex Deployed Responsive Service

    Science.gov (United States)

    Parry, Glenn; McLening, Marc; Caldwell, Nigel; Thompson, Rob

    A pizza restaurant must provide product, in the form of the food and drink, and service in the way this is delivered to the customer. Providing this has distinct operational challenges, but what if the restaurant also provides a home delivery service? The service becomes deployed as the customer is no-longer co-located with the production area. The business challenge is complicated as service needs to be delivered within a geographic region, to time or the pizza will be cold, and within a cost that is not ­prohibitive. It must also be responsive to short term demand; needing to balance the number of staff it has available to undertake deliveries against a forecast of demand.

  9. CCT deployment considerations

    International Nuclear Information System (INIS)

    Yamagata, B.

    1993-01-01

    The deployment of Clean Coal Technologies (CCT) is discussed by asserting that in the case of commercializing CCT, the government's involvement should not stop at the demonstration gate. Two areas in this regard are described. First, the need for the domestic DOE CCT Program to focus on the domestic deployment of demonstrated technologies, and second, the need to recognize that to participate in the phenomenal growth of international power markets through use of clean coal or advanced coal technologies an aggressive partnering between the government and industry to demonstrate technologies abroad will be required. The Clean Coal Technology Coalition's (CCT) primary mission has been to promote the development and use of CCTs. The CCT is a strong advocate for the DOE CCT Program and applauds the Department's and industry's success at developing many coal-based technologies. By current design, the DOE program is said to go no further than the initial demonstration of a technology. Since the inception of CCT in 1986, the Coalition has advocated the need to pursue a partnership with government in which more than one demonstration of the same or similar technology is supported by the clean coal program. Only in this way can one be assured of widespread acceptance of any given technology. There exists a gap (call it a open-quotes risk gapclose quotes) between CCTs that have been successfully demonstrated (and presumably available for commercial use) and their widespread commercial use. A technology matrix has been developed in which the developmental status of a variety of clean coal technologies is demonstrated. While still too early to pass judgment, it appears that while success is being achieved in demonstrating advanced coal technologies, the market place - for several reasons - is not, indeed may have no plans, to adopt these technologies

  10. CMS software deployment on OSG

    International Nuclear Information System (INIS)

    Kim, B; Avery, P; Thomas, M; Wuerthwein, F

    2008-01-01

    A set of software deployment tools has been developed for the installation, verification, and removal of a CMS software release. The tools that are mainly targeted for the deployment on the OSG have the features of instant release deployment, corrective resubmission of the initial installation job, and an independent web-based deployment portal with Grid security infrastructure login mechanism. We have been deploying over 500 installations and found the tools are reliable and adaptable to cope with problems with changes in the Grid computing environment and the software releases. We present the design of the tools, statistics that we gathered during the operation of the tools, and our experience with the CMS software deployment on the OSG Grid computing environment

  11. CMS software deployment on OSG

    Energy Technology Data Exchange (ETDEWEB)

    Kim, B; Avery, P [University of Florida, Gainesville, FL 32611 (United States); Thomas, M [California Institute of Technology, Pasadena, CA 91125 (United States); Wuerthwein, F [University of California at San Diego, La Jolla, CA 92093 (United States)], E-mail: bockjoo@phys.ufl.edu, E-mail: thomas@hep.caltech.edu, E-mail: avery@phys.ufl.edu, E-mail: fkw@fnal.gov

    2008-07-15

    A set of software deployment tools has been developed for the installation, verification, and removal of a CMS software release. The tools that are mainly targeted for the deployment on the OSG have the features of instant release deployment, corrective resubmission of the initial installation job, and an independent web-based deployment portal with Grid security infrastructure login mechanism. We have been deploying over 500 installations and found the tools are reliable and adaptable to cope with problems with changes in the Grid computing environment and the software releases. We present the design of the tools, statistics that we gathered during the operation of the tools, and our experience with the CMS software deployment on the OSG Grid computing environment.

  12. Mastering Hyper-V Deployment

    CERN Document Server

    Finn, Aidan

    2010-01-01

    The only book to take an in-depth look at deploying Hyper-V. Now in its second generation, the popular Hyper-V boasts technical advances that create even more dynamic systems than ever before. This unique resource serves an authoritative guide to deploying Windows Server 2008 R2 Hyper-V comprehensively. Step-by-step instructions demonstrate how to design a Hyper-V deployment, build a Hyper-V host environment, and design a management system with System Center Virtual Machine Manager 2008 R2.: Features real-world examples that show you how to design a Hyper-V deployment, build a Hyper-V host env

  13. Infrastructure Engineering and Deployment Division

    Data.gov (United States)

    Federal Laboratory Consortium — Volpe's Infrastructure Engineering and Deployment Division advances transportation innovation by being leaders in infrastructure technology, including vehicles and...

  14. Rapid deployment intrusion detection system

    International Nuclear Information System (INIS)

    Graham, R.H.

    1997-01-01

    A rapidly deployable security system is one that provides intrusion detection, assessment, communications, and annunciation capabilities; is easy to install and configure; can be rapidly deployed, and is reusable. A rapidly deployable intrusion detection system (RADIDS) has many potential applications within the DOE Complex: back-up protection for failed zones in a perimeter intrusion detection and assessment system, intrusion detection and assessment capabilities in temporary locations, protection of assets during Complex reconfiguration, and protection in hazardous locations, protection of assets during Complex reconfiguration, and protection in hazardous locations. Many DOE user-need documents have indicated an interest in a rapidly deployable intrusion detection system. The purpose of the RADIDS project is to design, develop, and implement such a system. 2 figs

  15. Family Reintegration Following Guard Deployment

    Science.gov (United States)

    2010-09-20

    Somalia Peacekeepers. Journal of Consulting and Clinical Psychology, 72(5), 909-913. Haas DM . Pazdernik LA. Olsen CH. A cross-sectional survey of the...relationship between partner deployment and stress in pregnancy during wartime. Haas DM . Pazdernik LA. Partner deployment and stress in pregnant...Identify 3-5 key words relating to the proposal. (Required) I used MESH Headings instead of the CRISP Thesaurus for key

  16. Ancient DNA

    DEFF Research Database (Denmark)

    Willerslev, Eske; Cooper, Alan

    2004-01-01

    ancient DNA, palaeontology, palaeoecology, archaeology, population genetics, DNA damage and repair......ancient DNA, palaeontology, palaeoecology, archaeology, population genetics, DNA damage and repair...

  17. IPv6 deployment and management

    CERN Document Server

    Dooley, Michael

    2013-01-01

    A guide for understanding, deploying, and managing Internet Protocol version 6 The growth of the Internet has created a need for more addresses than are available with Internet Protocol version 4 (IPv4)-the protocol currently used to direct almost all Internet traffic. Internet Protocol version 6 (IPv6)-the new IP version intended to ultimately succeed IPv4-will expand the addressing capacity of the Internet to support the explosive growth of users and devices on the Internet as well as add flexibility to allocating addresses and efficiency for routing traffic. IPv6 Deploy

  18. Charge-transfer interactions of Cr species with DNA.

    Science.gov (United States)

    Nowicka, Anna M; Matysiak-Brynda, Edyta; Hepel, Maria

    2017-10-01

    Interactions of Cr species with nucleic acids in living organisms depend strongly on Cr oxidation state and the environmental conditions. As the effects of these interactions range from benign to pre-mutagenic to carcinogenic, careful assessment of the hazard they pose to human health is necessary. We have investigated methods that would enable quantifying the DNA damage caused by Cr species under varying environmental conditions, including UV, O 2 , and redox potential, using simple instrumental techniques which could be in future combined into a field-deployable instrumentation. We have employed electrochemical quartz crystal nanogravimetry (EQCN), cyclic voltammetry (CV), and electrochemical impedance spectroscopy (EIS) to evaluate the extent of DNA damage expressed in terms of guanine oxidation yield (η) and changes in specific characteristics provided by these techniques. The effects of the interactions of Cr species with DNA were analyzed using a model calf thymus DNA (ctDNA) film on a gold electrode (Au@ctDNA) in different media, including: (i) Cr(VI), (ii) Cr(VI) reduced at -0.2V, (iii) Cr(III)+UV radiation+O 2 , and Cr(III), obtaining the η values: 7.4±1.4, 1.5±0.4, 1.1±0.31%, and 0%, respectively, thus quantifying the hazard posed. The EIS measurements have enabled utilizing the decrease in charge-transfer resistance (R ct ) for ferri/ferrocyanide redox probe at an Au@ctDNA electrode to assess the oxidative ctDNA damage by Cr(VI) species. In this case, circular dichroism indicates an extensive damage to the ctDNA hydrogen bonding. On the other hand, Cr(III) species have not induced any damage to ctDNA, although the EQCN measurements show an electrostatic binding to DNA. Copyright © 2017 Elsevier Inc. All rights reserved.

  19. When Loved Ones Get Deployed

    Science.gov (United States)

    ... different from hearing about conflicts and violence that break out in the world during our own time. If someone you care about is in the military and is deployed for duty, it's natural to worry about their safety. That's especially true if the person is going ...

  20. Non-traditional Infrasound Deployment

    Science.gov (United States)

    McKenna, M. H.; McComas, S.; Simpson, C. P.; Diaz-Alvarez, H.; Costley, R. D.; Hayward, C.; Golden, P.; Endress, A.

    2017-12-01

    Historically, infrasound arrays have been deployed in rural environments where anthropological noise sources are limited. As interest in monitoring low energy sources at local distances grows in the infrasound community, it will be vital to understand how to monitor infrasound sources in an urban environment. Arrays deployed in urban centers have to overcome the decreased signal-to-noise ratio and reduced amount of real estate available to deploy an array. To advance the understanding of monitoring infrasound sources in urban environments, local and regional infrasound arrays were deployed on building rooftops on the campus at Southern Methodist University (SMU), and data were collected for one seasonal cycle. The data were evaluated for structural source signals (continuous-wave packets), and when a signal was identified, the back azimuth to the source was determined through frequency-wavenumber analysis. This information was used to identify hypothesized structural sources; these sources were verified through direct measurement and dynamic structural analysis modeling. In addition to the rooftop arrays, a camouflaged infrasound sensor was installed on the SMU campus and evaluated to determine its effectiveness for wind noise reduction. Permission to publish was granted by Director, Geotechnical and Structures Laboratory.

  1. SATWG networked quality function deployment

    Science.gov (United States)

    Brown, Don

    1992-01-01

    The initiative of this work is to develop a cooperative process for continual evolution of an integrated, time phased avionics technology plan that involves customers, technologists, developers, and managers. This will be accomplished by demonstrating a computer network technology to augment the Quality Function Deployment (QFD). All results are presented in viewgraph format.

  2. A highly optimized grid deployment: the metagenomic analysis example.

    Science.gov (United States)

    Aparicio, Gabriel; Blanquer, Ignacio; Hernández, Vicente

    2008-01-01

    Computational resources and computationally expensive processes are two topics that are not growing at the same ratio. The availability of large amounts of computing resources in Grid infrastructures does not mean that efficiency is not an important issue. It is necessary to analyze the whole process to improve partitioning and submission schemas, especially in the most critical experiments. This is the case of metagenomic analysis, and this text shows the work done in order to optimize a Grid deployment, which has led to a reduction of the response time and the failure rates. Metagenomic studies aim at processing samples of multiple specimens to extract the genes and proteins that belong to the different species. In many cases, the sequencing of the DNA of many microorganisms is hindered by the impossibility of growing significant samples of isolated specimens. Many bacteria cannot survive alone, and require the interaction with other organisms. In such cases, the information of the DNA available belongs to different kinds of organisms. One important stage in Metagenomic analysis consists on the extraction of fragments followed by the comparison and analysis of their function stage. By the comparison to existing chains, whose function is well known, fragments can be classified. This process is computationally intensive and requires of several iterations of alignment and phylogeny classification steps. Source samples reach several millions of sequences, which could reach up to thousands of nucleotides each. These sequences are compared to a selected part of the "Non-redundant" database which only implies the information from eukaryotic species. From this first analysis, a refining process is performed and alignment analysis is restarted from the results. This process implies several CPU years. The article describes and analyzes the difficulties to fragment, automate and check the above operations in current Grid production environments. This environment has been

  3. Advanced Deployable Structural Systems for Small Satellites

    Science.gov (United States)

    Belvin, W. Keith; Straubel, Marco; Wilkie, W. Keats; Zander, Martin E.; Fernandez, Juan M.; Hillebrandt, Martin F.

    2016-01-01

    One of the key challenges for small satellites is packaging and reliable deployment of structural booms and arrays used for power, communication, and scientific instruments. The lack of reliable and efficient boom and membrane deployment concepts for small satellites is addressed in this work through a collaborative project between NASA and DLR. The paper provides a state of the art overview on existing spacecraft deployable appendages, the special requirements for small satellites, and initial concepts for deployable booms and arrays needed for various small satellite applications. The goal is to enhance deployable boom predictability and ground testability, develop designs that are tolerant of manufacturing imperfections, and incorporate simple and reliable deployment systems.

  4. Designing and Deploying Programming Courses: Strategies, Tools, Difficulties and Pedagogy

    Science.gov (United States)

    Xinogalos, Stelios

    2016-01-01

    Designing and deploying programming courses is undoubtedly a challenging task. In this paper, an attempt to analyze important aspects of a sequence of two courses on imperative-procedural and object-oriented programming in a non-CS majors Department is made. This analysis is based on a questionnaire filled in by fifty students in a voluntary…

  5. Supply strategy for SMR deployment

    International Nuclear Information System (INIS)

    Coccagna, A.F.

    2013-01-01

    This document provides a description of Babcock and Wilcox's deployment strategy for the mPower™ Small Modular Reactor from the perspective of Supply Chain and Manufacturing. A desirable future state of readiness is described as one which leverages and revitalizes an existing supply chain and manufacturing infrastructure, as well as leveraging an existing workforce of engineering, construction, and project management employees. B and W's mPower™ SMR value proposition offers many desired design and operating advantages to the SMR market. (author)

  6. Hadoop Cluster Deployment: A Methodological Approach

    Directory of Open Access Journals (Sweden)

    Ronaldo Celso Messias Correia

    2018-05-01

    Full Text Available For a long time, data has been treated as a general problem because it just represents fractions of an event without any relevant purpose. However, the last decade has been just about information and how to get it. Seeking meaning in data and trying to solve scalability problems, many frameworks have been developed to improve data storage and its analysis. As a framework, Hadoop was presented as a powerful tool to deal with large amounts of data. However, it still causes doubts about how to deal with its deployment and if there is any reliable method to compare the performance of distinct Hadoop clusters. This paper presents a methodology based on benchmark analysis to guide the Hadoop cluster deployment. The experiments employed The Apache Hadoop and the Hadoop distributions of Cloudera, Hortonworks, and MapR, analyzing the architectures on local and on clouding—using centralized and geographically distributed servers. The results show the methodology can be dynamically applied on a reliable comparison among different architectures. Additionally, the study suggests that the knowledge acquired can be used to improve the data analysis process by understanding the Hadoop architecture.

  7. Regional Energy Deployment System (ReEDS)

    Energy Technology Data Exchange (ETDEWEB)

    Short, W.; Sullivan, P.; Mai, T.; Mowers, M.; Uriarte, C.; Blair, N.; Heimiller, D.; Martinez, A.

    2011-12-01

    The Regional Energy Deployment System (ReEDS) is a deterministic optimization model of the deployment of electric power generation technologies and transmission infrastructure throughout the contiguous United States into the future. The model, developed by the National Renewable Energy Laboratory's Strategic Energy Analysis Center, is designed to analyze the critical energy issues in the electric sector, especially with respect to potential energy policies, such as clean energy and renewable energy standards or carbon restrictions. ReEDS provides a detailed treatment of electricity-generating and electrical storage technologies and specifically addresses a variety of issues related to renewable energy technologies, including accessibility and cost of transmission, regional quality of renewable resources, seasonal and diurnal generation profiles, variability of wind and solar power, and the influence of variability on the reliability of the electrical grid. ReEDS addresses these issues through a highly discretized regional structure, explicit statistical treatment of the variability in wind and solar output over time, and consideration of ancillary services' requirements and costs.

  8. Transitioning Submersible Chemical Analyzer Technologies for Sustained, Autonomous Observations from Profiling Moorings, Gliders and other AUVs

    National Research Council Canada - National Science Library

    Hanson, Alfred K; Donaghay, Percy L; Moore, Casey; Arrieta, Richard

    2005-01-01

    The long term goal is to transition existing prototype autonomous profiling nutrient analyzers into commercial products that can be readily deployed on autonomous profiling moorings, coastal gliders...

  9. Transitioning Submersible Chemical Analyzer Technologies for Sustained, Autonomous Observations From Profiling Moorings, Gliders and other AUVs

    National Research Council Canada - National Science Library

    Hanson, Alfred K; Donaghay, Percy L; Moore, Casey; Arrieta, Richard

    2006-01-01

    The long term goal is to transition existing prototype autonomous profiling nutrient analyzers into commercial products that can be readily deployed on autonomous profiling moorings, coastal gliders...

  10. Partial pressure (or fugacity) of carbon dioxide, pH (on total scale), salinity and other variables collected from time series observations using Bubble type equilibrator for autonomous carbon dioxide (CO2) measurement, Carbon dioxide (CO2) gas analyzer and other instruments from MOORING BOBOA_90E_15N deployments 1 and 2 in the Bay of Bengal, Indian Ocean from 2013-11-24 to 2015-06-19 (NCEI Accession 0162473)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NCEI Accession 0162473 includes chemical, meteorological, physical time series data collected from BOBOA_90E_15N deployments 1 and 2 in the Bay of Bengal, Indian...

  11. Remote Laser Diffraction PSD Analyzer

    International Nuclear Information System (INIS)

    Batcheller, T.A.; Huestis, G.M.; Bolton, S.M.

    2000-01-01

    Particle size distribution (PSD) analysis of radioactive slurry samples were obtained using a modified off-the-shelf classical laser light scattering particle size analyzer. A Horiba Instruments Inc. Model La-300 PSD analyzer, which has a 0.1 to 600 micron measurement range, was modified for remote application in a hot cell (gamma radiation) environment. The general details of the modifications to this analyzer are presented in this paper. This technology provides rapid and simple PSD analysis, especially down in the fine and microscopic particle size regime. Particle size analysis of these radioactive slurries down in this smaller range was not achievable - making this technology far superior than the traditional methods used previously. Remote deployment and utilization of this technology is in an exploratory stage. The risk of malfunction in this radiation environment is countered by gaining of this tremendously useful fundamental engineering data. Successful acquisition of this data, in conjunction with other characterization analyses, provides important information that can be used in the myriad of potential radioactive waste management alternatives

  12. Remote Laser Diffraction PSD Analyzer

    International Nuclear Information System (INIS)

    Batcheller, Thomas Aquinas; Huestis, Gary Michael; Bolton, Steven Michael

    2000-01-01

    Particle size distribution (PSD) analysis of radioactive slurry samples were obtained using a modified ''off-the-shelf'' classical laser light scattering particle size analyzer. A Horiba Instruments Inc. Model La-300 PSD analyzer, which has a 0.1 to 600 micron measurement range, was modified for remote application in a ''hot cell'' (gamma radiation) environment. The general details of the modifications to this analyzer are presented in this paper. This technology provides rapid and simple PSD analysis, especially down in the fine and microscopic particle size regime. Particle size analysis of these radioactive slurries down in this smaller range was not achievable--making this technology far superior than the traditional methods used previously. Remote deployment and utilization of this technology is in an exploratory stage. The risk of malfunction in this radiation environment is countered by gaining of this tremendously useful fundamental engineering data. Successful acquisition of this data, in conjunction with other characterization analyses, provides important information that can be used in the myriad of potential radioactive waste management alternatives

  13. Software, component, and service deployment in computational Grids

    International Nuclear Information System (INIS)

    von Laszewski, G.; Blau, E.; Bletzinger, M.; Gawor, J.; Lane, P.; Martin, S.; Russell, M.

    2002-01-01

    Grids comprise an infrastructure that enables scientists to use a diverse set of distributed remote services and resources as part of complex scientific problem-solving processes. We analyze some of the challenges involved in deploying software and components transparently in Grids. We report on three practical solutions used by the Globus Project. Lessons learned from this experience lead us to believe that it is necessary to support a variety of software and component deployment strategies. These strategies are based on the hosting environment

  14. Deployment and Implementation Strategies for Massive MIMO in 5G

    DEFF Research Database (Denmark)

    Panzner, Berthold; Zirwas, Wolfgang; Dierks, Stefan

    2015-01-01

    for 5G is a successful and cost-efficient integration in the overall network concept. This work highlights deployment and implementation strategies for massive MIMO in the context of 5G indoor small cell scenarios. Different massive MIMO deployment scenarios are analyzed for a standard 3GPP indoor...... to spatial streams is varied stepwise from equality to a factor of ten. For implementation of massive MIMO in 5G networks trends in beamforming techniques, mutually coupled subarrays, over the calibration procedure and estimated ADC performance in 2020 time-frame are discussed. Based on the debate the paper...

  15. Scientific data management challenges, technology and deployment

    CERN Document Server

    Rotem, Doron

    2010-01-01

    Dealing with the volume, complexity, and diversity of data currently being generated by scientific experiments and simulations often causes scientists to waste productive time. Scientific Data Management: Challenges, Technology, and Deployment describes cutting-edge technologies and solutions for managing and analyzing vast amounts of data, helping scientists focus on their scientific goals. The book begins with coverage of efficient storage systems, discussing how to write and read large volumes of data without slowing the simulation, analysis, or visualization processes. It then focuses on the efficient data movement and management of storage spaces and explores emerging database systems for scientific data. The book also addresses how to best organize data for analysis purposes, how to effectively conduct searches over large datasets, how to successfully automate multistep scientific process workflows, and how to automatically collect metadata and lineage information. This book provides a comprehensive u...

  16. DNA damage and autophagy

    International Nuclear Information System (INIS)

    Rodriguez-Rocha, Humberto; Garcia-Garcia, Aracely; Panayiotidis, Mihalis I.; Franco, Rodrigo

    2011-01-01

    Both exogenous and endogenous agents are a threat to DNA integrity. Exogenous environmental agents such as ultraviolet (UV) and ionizing radiation, genotoxic chemicals and endogenous byproducts of metabolism including reactive oxygen species can cause alterations in DNA structure (DNA damage). Unrepaired DNA damage has been linked to a variety of human disorders including cancer and neurodegenerative disease. Thus, efficient mechanisms to detect DNA lesions, signal their presence and promote their repair have been evolved in cells. If DNA is effectively repaired, DNA damage response is inactivated and normal cell functioning resumes. In contrast, when DNA lesions cannot be removed, chronic DNA damage triggers specific cell responses such as cell death and senescence. Recently, DNA damage has been shown to induce autophagy, a cellular catabolic process that maintains a balance between synthesis, degradation, and recycling of cellular components. But the exact mechanisms by which DNA damage triggers autophagy are unclear. More importantly, the role of autophagy in the DNA damage response and cellular fate is unknown. In this review we analyze evidence that supports a role for autophagy as an integral part of the DNA damage response.

  17. Vibration characteristics of a deployable controllable-geometry truss boom

    Science.gov (United States)

    Dorsey, J. T.

    1983-01-01

    An analytical study was made to evaluate changes in the fundamental frequency of a two dimensional cantilevered truss boom at various stages of deployment. The truss could be axially deployed or retracted and undergo a variety of controlled geometry changes by shortening or lengthening the telescoping diagonal members in each bay. Both untapered and tapered versions of the truss boom were modeled and analyzed by using the finite element method. Large reductions in fundamental frequency occurred for both the untapered and tapered trusses when they were uniformly retracted or maneuvered laterally from their fully deployed position. These frequency reductions can be minimized, however, if truss geometries are selected which maintain cantilever root stiffness during truss maneuvers.

  18. RSG Deployment Case Testing Results

    Energy Technology Data Exchange (ETDEWEB)

    Owsley, Stanley L.; Dodson, Michael G.; Hatchell, Brian K.; Seim, Thomas A.; Alexander, David L.; Hawthorne, Woodrow T.

    2005-09-01

    The RSG deployment case design is centered on taking the RSG system and producing a transport case that houses the RSG in a safe and controlled manner for transport. The transport case was driven by two conflicting constraints, first that the case be as light as possible, and second that it meet a stringent list of Military Specified requirements. The design team worked to extract every bit of weight from the design while striving to meet the rigorous Mil-Spec constraints. In the end compromises were made primarily on the specification side to control the overall weight of the transport case. This report outlines the case testing results.

  19. Supporting Knowledge Transfer in IS Deployment Projects

    Science.gov (United States)

    Schönström, Mikael

    To deploy new information systems is an expensive and complex task, and does seldom result in successful usage where the system adds strategic value to the firm (e.g. Sharma et al. 2003). It has been argued that innovation diffusion is a knowledge integration problem (Newell et al. 2000). Knowledge about business processes, deployment processes, information systems and technology are needed in a large-scale deployment of a corporate IS. These deployments can therefore to a large extent be argued to be a knowledge management (KM) problem. An effective deployment requires that knowledge about the system is effectively transferred to the target organization (Ko et al. 2005).

  20. Design and analysis of a deployable truss for the large modular mesh antenna

    Science.gov (United States)

    Meguro, Akira

    This paper describes the design and deployment analysis for large deployable modular mesh antennas. Key design criteria are deployability, and the driving force and latching moment requirements. Reaction forces and moments due to mesh and cable network seriously influence the driving force. These forces and moments can be precisely estimated by means of analyzing the cable network using Cable Structure Analyzer (CASA). Deployment analysis is carried out using Dynamic Analysis and Design System (DADS). The influence of alignment errors on the driving reaction force can be eliminated by replacing the joint element with a spring element. The joint slop is also modeled using a discontinuous spring elements. Their design approach for three types of deployable modules and the deployment characterstics of three Bread-Board Models based on those designs are also presented. In order to study gravity effects on the deployment characteristics and the effects of the gravity compensation method, ground deployment analysis is carried out. A planned deployment test that will use aircraft parabolic flight to simulate a micro-gravity environment is also described.

  1. A field-deployable mobile molecular diagnostic system for malaria at the point of need.

    Science.gov (United States)

    Choi, Gihoon; Song, Daniel; Shrestha, Sony; Miao, Jun; Cui, Liwang; Guan, Weihua

    2016-11-01

    In response to the urgent need of a field-deployable and highly sensitive malaria diagnosis, we developed a standalone, "sample-in-answer-out" molecular diagnostic system (AnyMDx) to enable quantitative molecular analysis of blood-borne malaria in low resource areas. The system consists of a durable battery-powered analyzer and a disposable microfluidic compact disc loaded with reagents ready for use. A low power thermal module and a novel fluorescence-sensing module are integrated into the analyzer for real-time monitoring of loop-mediated isothermal nucleic acid amplification (LAMP) of target parasite DNA. With 10 μL of raw blood sample, the AnyMDx system automates the nucleic acid sample preparation and subsequent LAMP and real-time detection. Under laboratory conditions with whole-blood samples spiked with cultured Plasmodium falciparum, we achieved a detection limit of ∼0.6 parasite per μL, much lower than those for the conventional microscopy and rapid diagnostic tests (∼50-100 parasites per μL). The turnaround time from sample to answer is less than 40 minutes. The AnyMDx is user-friendly requiring minimal technological training. The analyzer and the disposable reagent compact discs are cost-effective, making AnyMDx a potential tool for malaria molecular diagnosis under field settings for malaria elimination.

  2. Biophysics of DNA

    CERN Document Server

    Vologodskii, Alexander

    2015-01-01

    Surveying the last sixty years of research, this book describes the physical properties of DNA in the context of its biological functioning. It is designed to enable both students and researchers of molecular biology, biochemistry and physics to better understand the biophysics of DNA, addressing key questions and facilitating further research. The chapters integrate theoretical and experimental approaches, emphasising throughout the importance of a quantitative knowledge of physical properties in building and analysing models of DNA functioning. For example, the book shows how the relationship between DNA mechanical properties and the sequence specificity of DNA-protein binding can be analyzed quantitatively by using our current knowledge of the physical and structural properties of DNA. Theoretical models and experimental methods in the field are critically considered to enable the reader to engage effectively with the current scientific literature on the physical properties of DNA.

  3. Fluorescence Microscopy of Nanochannel-Confined DNA.

    Science.gov (United States)

    Westerlund, Fredrik; Persson, Fredrik; Fritzsche, Joachim; Beech, Jason P; Tegenfeldt, Jonas O

    2018-01-01

    Stretching of DNA in nanoscale confinement allows for several important studies. The genetic contents of the DNA can be visualized on the single DNA molecule level and both the polymer physics of confined DNA and also DNA/protein and other DNA/DNA-binding molecule interactions can be explored. This chapter describes the basic steps to fabricate the nanostructures, perform the experiments and analyze the data.

  4. Airbag deployment-related eye injuries.

    Science.gov (United States)

    Koisaari, Tapio; Leivo, Tiina; Sahraravand, Ahmad; Haavisto, Anna-Kaisa; Sulander, Pekka; Tervo, Timo M T

    2017-07-04

    We studied the correlation between airbag deployment and eye injuries using 2 different data sets. The registry of the Finnish Road Accident (FRA) Investigation Teams was analyzed to study severe head- and eyewear-related injuries. All fatal passenger car or van accidents that occurred during the years 2009-2012 (4 years) were included (n = 734). Cases in which the driver's front airbag was deployed were subjected to analysis (n = 409). To determine the proportion of minor, potentially airbag-related eye injuries, the results were compared to the data for all new eye injury patients (n = 1,151) recorded at the Emergency Clinic of the Helsinki University Eye Hospital (HUEH) during one year, from May 1, 2011, to April 30, 2012. In the FRA data set, the unbelted drivers showed a significantly higher risk of death (odds ratio [OR] = 5.89, 95% confidence interval [CI], 3.33-10.9, P = 2.6E-12) or of sustaining head injuries (OR = 2.50, 95% CI, 1.59-3.97, P = 3.8E-5). Only 4 of the 1,151 HUEH patients were involved in a passenger car accident. In one of the crashes, the airbag operated, and the belted driver received 2 sutured eye lid wounds and showed conjunctival sugillation. No permanent eye injuries were recorded during the follow-up. The calculated annual airbag-related eye injury incidence was less than 1/1,000,000 people, 4/100,000 accidents, and 4/10,000 injured occupants. Airbag-related eye injuries occurred very rarely in car accidents in cases where the occupant survived and the restraint system was appropriately used. Spectacle use did not appear to increase the risk of eye injury in restrained occupants.

  5. Rapid detection and quantification of cell free cytomegalovirus by a high-speed centrifugation-based microculture assay: comparison to longitudinally analyzed viral DNA load and pp67 late transcript during lactation.

    Science.gov (United States)

    Hamprecht, Klaus; Witzel, Simone; Maschmann, Jens; Dietz, Klaus; Baumeister, Andrea; Mikeler, Elfriede; Goelz, Rangmar; Speer, Christian P; Jahn, Gerhard

    2003-12-01

    Human cytomegalovirus (HCMV) is reactivated in nearly every seropositive breastfeeding mother during lactation [Lancet 357 (2001) 513]. Conventional tissue culture (TC) and low-speed centrifugation-enhanced microtiter culture methods are not able to detect HCMV from milk during all stages of lactation. Development of a sensitive and quantitative microculture technique to describe the dynamics of HCMV reactivation in different milk compartments during lactation. Milk samples were collected longitudinally from seropositive breastfeeding mothers of preterm infants. Native milk samples were separated into fraction 1 (aqueous extract of milk fat), fraction 2 (cell and fat free milk whey) and fraction 3 (milk cells). Each of these fractions was screened qualitatively (TC, nPCR, pp67 late mRNA) and quantitatively (high-speed centrifugation-based microculture, quantitative PCR). Prior to low-speed centrifugation-enhanced inoculation, virus particles were concentrated by high-speed centrifugation (60 min at 50,000 x g, 4 degrees C). Using fraction 2 we were able to describe the dynamics of viral reactivation during lactation. We present the course of the quantitative virolactia and DNAlactia and qualitative detection of HCMV pp67 late mRNA in milk whey of four mothers (three transmitters and one non-transmitter). In all these cases virolactia described an unimodal and self limited course. Peak levels of virolactia for transmitters (T1: day 44; T2: day 43; T3: day 50) were closely related the onset of viruria of the corresponding preterm infants (U1: day 39; U2a/U2b: day 44/57; U3: day 60). The courses of viral load coincidence with the courses of DNA load. We present a rapid and highly sensitive microculture method for the quantification of cell free HCMV from milk whey and aqueous extracts from milk fat. Viral reactivation during lactation describes an unimodal course. Our findings have strong implications for quality control of any virus inactivation procedure.

  6. DNA barcoding of vouchered xylarium wood specimens of nine endangered Dalbergia species.

    Science.gov (United States)

    Yu, Min; Jiao, Lichao; Guo, Juan; Wiedenhoeft, Alex C; He, Tuo; Jiang, Xiaomei; Yin, Yafang

    2017-12-01

    ITS2+ trnH - psbA was the best combination of DNA barcode to resolve the Dalbergia wood species studied. We demonstrate the feasibility of building a DNA barcode reference database using xylarium wood specimens. The increase in illegal logging and timber trade of CITES-listed tropical species necessitates the development of unambiguous identification methods at the species level. For these methods to be fully functional and deployable for law enforcement, they must work using wood or wood products. DNA barcoding of wood has been promoted as a promising tool for species identification; however, the main barrier to extensive application of DNA barcoding to wood is the lack of a comprehensive and reliable DNA reference library of barcodes from wood. In this study, xylarium wood specimens of nine Dalbergia species were selected from the Wood Collection of the Chinese Academy of Forestry and DNA was then extracted from them for further PCR amplification of eight potential DNA barcode sequences (ITS2, matK, trnL, trnH-psbA, trnV-trnM1, trnV-trnM2, trnC-petN, and trnS-trnG). The barcodes were tested singly and in combination for species-level discrimination ability by tree-based [neighbor-joining (NJ)] and distance-based (TaxonDNA) methods. We found that the discrimination ability of DNA barcodes in combination was higher than any single DNA marker among the Dalbergia species studied, with the best two-marker combination of ITS2+trnH-psbA analyzed with NJ trees performing the best (100% accuracy). These barcodes are relatively short regions (wood as the source material, a necessary factor to apply DNA barcoding to timber trade. The present results demonstrate the feasibility of using vouchered xylarium specimens to build DNA barcoding reference databases.

  7. Noninvasive monitoring of the genetic evolution of EGFR-mutant non-small-cell lung cancer by analyzing circulating tumor DNA during combination chemotherapy with gefitinib and pemetrexed or S-1

    Directory of Open Access Journals (Sweden)

    Nakahara Y

    2016-08-01

    . Four patients underwent gefitinib plus pemetrexed therapy, and five patients underwent gefitinib and S-1 therapy. The median number of cycles delivered was five, and the median progression-free survival was 5.7 months. Efficacy outcomes did not differ between treatments. After the combination therapy, plasma T790M status changed to positive in two patients. Hepatocyte growth factor level did not significantly change through the combination therapy.Conclusion: The usefulness of monitoring the genetic evolution of EGFR-driven tumors using noninvasive procedures was demonstrated. Since continuation of EGFR-TKI therapy with cytotoxic agents has an acceptable tolerability and a possibility of inducing T790M mutation, the combination therapy may be useful for EGFR-mutant NSCLC resistant to EGFR-TKI therapy without T790M mutation. Keywords: circulating tumor DNA, epidermal growth factor receptor, gefitinib, S-1, pemetrexed

  8. Reintegration Difficulty of Military Couples Following Deployment

    Science.gov (United States)

    2016-07-01

    Response rate for Wave 8 = 88% Our final sample contained 554 men and 556 women (n = 554 cross- sex couples, 1 same- sex couple). Individuals were...story in the Killeen Daily Herald (10 April 2016) http://kdhnews.com/news/local/ kids -deployments-when-a-parent-deploys-children-face- tough...years old), and (c) “Me getting sick and having to go to sick call.” (deployed Army husband, 25 years old). Sex and fidelity. Comments fell into

  9. Security Support in Continuous Deployment Pipeline

    DEFF Research Database (Denmark)

    Ullah, Faheem; Raft, Adam Johannes; Shahin, Mojtaba

    2017-01-01

    Continuous Deployment (CD) has emerged as a new practice in the software industry to continuously and automatically deploy software changes into production. Continuous Deployment Pipeline (CDP) supports CD practice by transferring the changes from the repository to production. Since most of the CDP...... penetration tools. Our findings indicate that the applied tactics improve the security of the major components (i.e., repository, continuous integration server, main server) of a CDP by controlling access to the components and establishing secure connections....

  10. Web server attack analyzer

    OpenAIRE

    Mižišin, Michal

    2013-01-01

    Web server attack analyzer - Abstract The goal of this work was to create prototype of analyzer of injection flaws attacks on web server. Proposed solution combines capabilities of web application firewall and web server log analyzer. Analysis is based on configurable signatures defined by regular expressions. This paper begins with summary of web attacks, followed by detection techniques analysis on web servers, description and justification of selected implementation. In the end are charact...

  11. Electron attachment analyzer

    International Nuclear Information System (INIS)

    Popp, P.; Grosse, H.J.; Leonhardt, J.; Mothes, S.; Oppermann, G.

    1984-01-01

    The invention concerns an electron attachment analyzer for detecting traces of electroaffine substances in electronegative gases, especially in air. The analyzer can be used for monitoring working places, e. g., in operating theatres. The analyzer consists of two electrodes inserted in a base frame of insulating material (quartz or ceramics) and a high-temperature resistant radiation source ( 85 Kr, 3 H, or 63 Ni)

  12. Solar array deployment analysis considering path-dependent behavior of a tape spring hinge

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Kyung Won; Park, Young Jin [KAIST, Daejeon (Korea, Republic of)

    2015-05-15

    Solar array deployment analysis is conducted considering the path-dependent nonlinear behavior of tape spring hinge. Such hinges offer many advantages over rigid hinges; they are self-deployable, self-locking, lightweight, and simple. However, they show strongly nonlinear behavior with respect to rotation angle, making deployment analysis difficult. To accurately consider the characteristics of tape spring hinges for deployment analysis, a path-dependent path identification (PI) method for tracing the previous path of the moment is introduced. To analyze the deployment motion, the governing equation for solar array deployment is derived within the framework of Kane's dynamic equation for three deployable solar panels. The numerical solution is compared with the Recurdyn's multi-body dynamics analysis solution using experimentally measured moment-rotation profiles. Solar array deployment analysis is conducted by considering and not considering the path-dependent PI method. This simulation example shows that the proposed path-dependent PI method is very effective for accurately predicting the deployment motion.

  13. Low Mass Aeroshell Deployment Mechanism, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — Cornerstone Research Group Inc. (CRG) will develop new shape memory polymer (SMP) deployment mechanisms for actuating thermal protective systems (TPS) panels to...

  14. Low Mass Aeroshell Deployment Mechanism, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — Cornerstone Research Group Inc. (CRG) will develop new shape memory polymer (SMP) deployment mechanisms for actuating thermal protection system (TPS) panels to...

  15. Features of the Calculation Deployment Large Transformable Structures of Different Configurations

    Directory of Open Access Journals (Sweden)

    V. N. Zimin

    2014-01-01

    Full Text Available Despite the significant progress achieved in the design of space transformable structures to ensure a smooth and reliable deployment remains an important task. This type of construction can consist of dozens, hundreds or even thousands of interconnected elements. Deployment transformable space structures in orbit to test their performance in orbital conditions are associated with high material costs. Full deploy: experimental development process transformable structures involve a number of fundamental difficulties: It is impossible to eliminate the influence of gravity and resistance forces conditions. Thus, to calculate deploy of large transformable structures of various configurations is an important stage of their creation. Simulation provides an opportunity to analyze various schemes of deploy, to reveal their advantages and possible disadvantages. For numerical analysis of deploy of such structures is necessary to use modern software modeling of the dynamics of multi-component of mechanical systems such as EULER and Adams. Simulation of deployment space transformable structures was performed taking as example folding flat antenna contours diameter of 5 m and 20 m, foldable spatial calibration reflector diameter of 3 m, deployable antenna reflector truss-type aperture 3×6 m.The results of the calculations represent following characteristics: the time of adoption of the working position structures; form intermediate positions structures during deployment; dependence of opening angles and angular velocities of the design links on the time. The parameters of these calculations can be used as input in the development of structural elements providing deployment. They can also be used to prepare stands for experimental testing of disclosure designs in ground conditions. It should be noted that the theoretical models are the only way to analyze the deployment of such structures for possible emergency situations.

  16. Injury and side impact air bag deployment in near and far sided motor vehicle crashes, United States, 2000-2005.

    Science.gov (United States)

    Stadter, Greg; Grabowski, Jurek G; Burke, Christine; Aldaghlas, Tayseer A; Robinson, Linda; Fakhry, Samir M

    2008-12-01

    Side impact crashes, the most lethal type, account for 26% of all motor vehicle crashes in the United States. The purpose of this study is to delineate side impact airbag (SIAB) deployment rates, injury rates, and analyze crash factors associated with SIAB deployment and occupant injury. All passenger vehicles equipped with SIABs that were involved in a side impact crash were identified from the National Automotive Sampling System database. Crashes with multiple impacts, ejections, unbelted drivers or rollovers were excluded from the study. The outcome variables of interest were SIAB deployment and driver injury. SIAB deployment was compared in similar crashes to analyze the impact on driver's injury severity score. Other crash factors were also examined to analyze what role they play in SIAB deployment rates and injury rates, such as plane of contact, striking object and Delta-V. The data set for this study contained 247 drivers in near and far side crashes in vehicles with installed SIABs. Overall SIAB deployment was 43% in side impact crashes. A significant factor associated with both the SIAB deployment rate and the driver's injury rate was increased Delta-V. SIABs do not deploy consistently in crashes with a high Delta-V or with a lateral primary direction of force and a front plane of contact. In these two scenarios, further research is warranted on SIAB deployments. With SIAB deployment, it appears drivers are able to sustain a higher Delta-V impact without serious injury.

  17. Nuclear power plant analyzer

    International Nuclear Information System (INIS)

    Stritar, A.

    1986-01-01

    The development of Nuclear Power Plant Analyzers in USA is described. There are two different types of Analyzers under development in USA, the forst in Idaho and Los Alamos national Lab, the second in brookhaven National lab. That one is described in detail. The computer hardware and the mathematical models of the reactor vessel thermalhydraulics are described. (author)

  18. Analyzing Peace Pedagogies

    Science.gov (United States)

    Haavelsrud, Magnus; Stenberg, Oddbjorn

    2012-01-01

    Eleven articles on peace education published in the first volume of the Journal of Peace Education are analyzed. This selection comprises peace education programs that have been planned or carried out in different contexts. In analyzing peace pedagogies as proposed in the 11 contributions, we have chosen network analysis as our method--enabling…

  19. Analyzing in the present

    DEFF Research Database (Denmark)

    Revsbæk, Line; Tanggaard, Lene

    2015-01-01

    The article presents a notion of “analyzing in the present” as a source of inspiration in analyzing qualitative research materials. The term emerged from extensive listening to interview recordings during everyday commuting to university campus. Paying attention to the way different parts of vari...

  20. Gearbox vibration diagnostic analyzer

    Science.gov (United States)

    1992-01-01

    This report describes the Gearbox Vibration Diagnostic Analyzer installed in the NASA Lewis Research Center's 500 HP Helicopter Transmission Test Stand to monitor gearbox testing. The vibration of the gearbox is analyzed using diagnostic algorithms to calculate a parameter indicating damaged components.

  1. Optimization Techniques for 3D Graphics Deployment on Mobile Devices

    Science.gov (United States)

    Koskela, Timo; Vatjus-Anttila, Jarkko

    2015-03-01

    3D Internet technologies are becoming essential enablers in many application areas including games, education, collaboration, navigation and social networking. The use of 3D Internet applications with mobile devices provides location-independent access and richer use context, but also performance issues. Therefore, one of the important challenges facing 3D Internet applications is the deployment of 3D graphics on mobile devices. In this article, we present an extensive survey on optimization techniques for 3D graphics deployment on mobile devices and qualitatively analyze the applicability of each technique from the standpoints of visual quality, performance and energy consumption. The analysis focuses on optimization techniques related to data-driven 3D graphics deployment, because it supports off-line use, multi-user interaction, user-created 3D graphics and creation of arbitrary 3D graphics. The outcome of the analysis facilitates the development and deployment of 3D Internet applications on mobile devices and provides guidelines for future research.

  2. Concurrent engineering: effective deployment strategies

    Directory of Open Access Journals (Sweden)

    Unny Menon

    1996-12-01

    Full Text Available This paper provides a comprehensive insight into current trends and developments in Concurrent Engineering for integrated development of products and processes with the goal of completing the entire cycle in a shorter time, at lower overall cost and with fewer engineering design changes after product release. The evolution and definition of Concurrent Engineering are addressed first, followed by a concise review of the following elements of the concurrent engineering approach to product development: Concept Development: The Front-End Process, identifying Customer Needs and Quality Function Deployment, Establishing Product Specifications, Concept Selection, Product Architecture, Design for Manufacturing, Effective Rapid Prototyping, and The Economics of Product Development. An outline of a computer-based tutorial developed by the authors and other graduate students funded by NASA ( accessible via the world-wide-web . is provided in this paper. A brief discussion of teamwork for successful concurrent engineering is included, t'ase histories of concurrent engineering implementation at North American and European companies are outlined with references to textbooks authored by Professor Menon and other writers. A comprehensive bibliography on concurrent engineering is included in the paper.

  3. Reintegration Difficulty of Military Couples Following Deployment

    Science.gov (United States)

    2017-07-01

    reintegration. Communication and Generalized Anxiety The emotional cycle of deployment model provides a descrip- tive framework for understanding the...counseling. Thus, communication can have a reciprocal influence on the very appraisals and emotions that motivate interaction in the first place. Communication...of service members back into family life after deployment can be extremely challenging for military couples. Understanding the factors that

  4. 5-Beam ADCP Deployment Strategy Considerations

    Science.gov (United States)

    Moore, T.; Savidge, D. K.; Gargett, A.

    2016-02-01

    With the increasing availability of 5 beam ADCPs and expanding opportunities for their deployment within both observatory and dedicated process study settings, refinements in deployment strategies are needed.Measuring vertical velocities directly with a vertically oriented acoustic beam requires that the instrument be stably mounted and leveled within fractions of a degree. Leveled shallow water deployments to date have utilized divers to jet pipes into the sand for stability, manually mount the instruments on the pipes, and level them. Leveling has been guided by the deployed instrument's pitch and roll output, available in real-time because of the observatory settings in which the deployments occurred. To expand the range of feasible deployments to deeper, perhaps non-real-time capable settings, alternatives to diver deployment and leveling must be considered. To determine stability requirements, mooring motion (heading, pitch and roll) has been sampled at 1Hz by gimballed ADCPs at a range of instrument deployment depths, and in shrouded and unshrouded cages. Conditions under which ADCP cages resting on the bottom experience significant shifts in tilt, roll or heading are assessed using co-located wind and wave measurements. The accuracy of estimating vertical velocities using all five beams relative to a well leveled vertical single beam is assessed from archived high frequency five beam data, to explore whether easing the leveling requirement is feasible.

  5. Analyzing policy support instruments and regulatory risk factors for wind energy deployment-A developers' perspective

    International Nuclear Information System (INIS)

    Luethi, Sonja; Praessler, Thomas

    2011-01-01

    A transition to a renewable energy system is high on the policy agenda in many countries. A promising energy source for a low-carbon energy future is wind. Policy-makers can attract wind energy development by providing attractive policy frameworks. This paper argues that apart from the level of financial support, both the risks stemming from the regulatory environment (legal security, administrative process and grid access) and the ability to finance projects play a critical role in determining the attractiveness of the development environment. It sheds light on how project developers trade off these different aspects and to what extent the attractiveness of a certain policy framework increases with the introduction of specific measures. Conjoint analysis is employed to provide empirical evidence on the preference of wind energy developers in the EU and the US. The analysis shows that developers' preferences are very similar across the studied regions and for different types of developers. Which policy measures could be most valuable depends on the specific existing environment. In some southeastern European countries, a reduction of administrative process duration may yield the highest utility gains, whereas, in the US, improvements in grid access regulation and an increase in remuneration levels may be more effective. - Highlights: → Paper suggests conjoint analysis as scenario tool for estimating potential effects of specific policy measures. → It provides a quantitative, empirical dataset of 119 onshore wind energy developers' preferences. → Results suggest that the aspects 'Legal security' and 'Remuneration' are important attributes. → Cluster analyses yields slightly different preferences for developers from EU and US.

  6. Miniature mass analyzer

    CERN Document Server

    Cuna, C; Lupsa, N; Cuna, S; Tuzson, B

    2003-01-01

    The paper presents the concept of different mass analyzers that were specifically designed as small dimension instruments able to detect with great sensitivity and accuracy the main environmental pollutants. The mass spectrometers are very suited instrument for chemical and isotopic analysis, needed in environmental surveillance. Usually, this is done by sampling the soil, air or water followed by laboratory analysis. To avoid drawbacks caused by sample alteration during the sampling process and transport, the 'in situ' analysis is preferred. Theoretically, any type of mass analyzer can be miniaturized, but some are more appropriate than others. Quadrupole mass filter and trap, magnetic sector, time-of-flight and ion cyclotron mass analyzers can be successfully shrunk, for each of them some performances being sacrificed but we must know which parameters are necessary to be kept unchanged. To satisfy the miniaturization criteria of the analyzer, it is necessary to use asymmetrical geometries, with ion beam obl...

  7. Renewable Energy: Policy Considerations for Deploying Renewables

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    This information paper accompanies the IEA publication Deploying Renewables 2011: Best and Future Policy Practice (IEA, 2011a). It provides more detailed data and analysis on policies for Deploying Renewables, and is intended to complement the main publication. It provides an account of the strategic drivers underpinning renewable energy (RE) technology deployment (energy security, economic development and environment protection) and assesses RE technologies with respect to these drivers, including an estimate of GHG emissions reductions due to RE technologies. The paper also explores the different barriers to deploying renewables at a given stage of market maturity and discusses what tools policy makers can avail of to succeed in removing deployment barriers. An additional topical highlight explores the challenges associated with accelerating the diffusion of RE technologies in developing countries.

  8. DNA Nanotechnology for Cancer Therapy

    Science.gov (United States)

    Kumar, Vinit; Palazzolo, Stefano; Bayda, Samer; Corona, Giuseppe; Toffoli, Giuseppe; Rizzolio, Flavio

    2016-01-01

    DNA nanotechnology is an emerging and exciting field, and represents a forefront frontier for the biomedical field. The specificity of the interactions between complementary base pairs makes DNA an incredible building material for programmable and very versatile two- and three-dimensional nanostructures called DNA origami. Here, we analyze the DNA origami and DNA-based nanostructures as a drug delivery system. Besides their physical-chemical nature, we dissect the critical factors such as stability, loading capability, release and immunocompatibility, which mainly limit in vivo applications. Special attention was dedicated to highlighting the boundaries to be overcome to bring DNA nanostructures closer to the bedside of patients. PMID:27022418

  9. Quality function deployment in launch operations

    Science.gov (United States)

    Portanova, P. L.; Tomei, E. J., Jr.

    1990-11-01

    The goal of the Advanced Launch System (ALS) is a more efficient launch capability that provides a highly reliable and operable system at substantially lower cost than current launch systems. Total Quality Management (TQM) principles are being emphasized throughout the ALS program. A continuous improvement philosophy is directed toward satisfying users' and customer's requirements in terms of quality, performance, schedule, and cost. Quality Function Deployment (QFD) is interpreted as the voice of the customer (or user), and it is an important planning tool in translating these requirements throughout the whole process of design, development, manufacture, and operations. This report explores the application of QFD methodology to launch operations, including the modification and addition of events (operations planning) in the engineering development cycle, and presents an informal status of study results to date. QFD is a technique for systematically analyzing the customer's (Space Command) perceptions of what constitutes a highly reliable and operable system and functionally breaking down those attributes to identify the critical characteristics that determine an efficient launch system capability. In applying the principle of QFD, a series of matrices or charts are developed with emphasis on the one commonly known as the House of Quality (because of its roof-like format), which identifies and translates the most critical information.

  10. TQM and lean strategy deployment in Italian hospitals.

    Science.gov (United States)

    Chiarini, Andrea; Baccarani, Claudio

    2016-10-03

    Purpose This paper aims to contribute to the debate concerning total quality management (TQM)-Lean strategy in public healthcare by analyzing the deployment path for implementation, the possible benefits that can be achieved and the encountered pitfalls. Design/methodology/approach Three case studies are drawn from three large Italian hospitals with more than 500 beds each and structured with many departments. The hospitals are located in Tuscany, Italy. These three hospitals have embraced TQM and Lean, starting from strategic objectives and their deployment. At the same time, they have also implemented many TQM-Lean tools. The case studies are based on interviews held with four managers in each of these three public hospitals. Findings Results from the interviews show that there is a specific deployment path for TQM-Lean implementation. The hospitals have also achieved benefits linked to patient satisfaction and improved organizational performances. Problems related to organizational and cultural issues, such as senior managers' commitment, staff management, manufacturing culture and tools adaptation, could affect the benefits. Research limitations/implications The research has been carried out in just three Italian public hospitals. Hence, similar investigations could be managed in other countries. Researchers could also use a larger sample and investigate these issues by means of quantitative inquiry. Practical implications Practitioners could try to apply the deployment path revealed by these case studies in other public and private hospitals. Originality/value The results of this research show that there is a specific, new deployment path for implementing TQM-Lean strategy in some public hospitals.

  11. Longitudinal changes in glucocorticoid receptor exon 1F methylation and psychopathology after military deployment.

    Science.gov (United States)

    Schür, R R; Boks, M P; Rutten, B P F; Daskalakis, N P; de Nijs, L; van Zuiden, M; Kavelaars, A; Heijnen, C J; Joëls, M; Kahn, R S; Geuze, E; Vermetten, E; Vinkers, C H

    2017-07-25

    Several cross-sectional studies have demonstrated the relevance of DNA methylation of the glucocorticoid receptor exon 1 F region (GR-1 F ) for trauma-related psychopathology. We conducted a longitudinal study to examine GR-1 F methylation changes over time in relation to trauma exposure and the development of post-deployment psychopathology. GR-1 F methylation (52 loci) was quantified using pyrosequencing in whole blood of 92 military men 1 month before and 6 months after a 4-month deployment period to Afghanistan. GR-1 F methylation overall (mean methylation and the number of methylated loci) and functional methylation (methylation at loci associated with GR exon 1 F expression) measures were examined. We first investigated the effect of exposure to potentially traumatic events during deployment on these measures. Subsequently, changes in GR-1 F methylation were related to changes in mental health problems (total Symptom Checklist-90 score) and posttraumatic stress disorder (PTSD) symptoms (Self-Report Inventory for PTSD). Trauma exposure during deployment was associated with an increase in all methylation measures, but development of mental health problems 6 months after deployment was only significantly associated with an increased functional methylation. Emergence of post-deployment PTSD symptoms was not related to increased functional methylation over time. Pre-deployment methylation levels did not predict post-deployment psychopathology. To our knowledge, this is the first study to prospectively demonstrate trauma-related increases in GR-1 F methylation, and it shows that only increases at specific functionally relevant sites predispose for post-deployment psychopathology.

  12. Histological Diagnoses of Military Personnel Undergoing Lung Biopsy After Deployment to Southwest Asia.

    Science.gov (United States)

    Madar, Cristian S; Lewin-Smith, Michael R; Franks, Teri J; Harley, Russell A; Klaric, John S; Morris, Michael J

    2017-08-01

    The current understanding of associations between lung disease and military deployment to Southwest Asia, including Iraq and Afghanistan, is both controversial and limited. We sought to clarify the relation between military deployment and biopsy-proven lung disease. Retrospective data were analyzed for military personnel with non-neoplastic lung biopsies evaluated at the Armed Forces Institute of Pathology or Joint Pathology Center (January 2005 to December 2012). Of 391 subjects, 137 (35.0%) had deployed to Southwest Asia prior to biopsy. Compared to non-deployed subjects, those deployed were younger (median age 37 vs. 51 years) with higher representation of African Americans (30.0 vs. 16.9%). Deployed patients were more likely diagnosed with non-necrotizing granulomas (OR 2.4). Non-deployed subjects had higher frequency of idiopathic interstitial pneumonias, particularly organizing pneumonia. Prevalence of small airways diseases including constrictive bronchiolitis was low. This study provides a broader understanding of diversity of biopsy-proven non-neoplastic lung disease as it relates to military deployment to Southwest Asia and importantly did not show an increased prevalence of small airway disease to include constrictive bronchiolitis.

  13. Extraction spectrophotometric analyzer

    International Nuclear Information System (INIS)

    Batik, J.; Vitha, F.

    1985-01-01

    Automation is discussed of extraction spectrophotometric determination of uranium in a solution. Uranium is extracted from accompanying elements in an HCl medium with a solution of tributyl phosphate in benzene. The determination is performed by measuring absorbance at 655 nm in a single-phase ethanol-water-benzene-tributyl phosphate medium. The design is described of an analyzer consisting of an analytical unit and a control unit. The analyzer performance promises increased productivity of labour, improved operating and hygiene conditions, and mainly more accurate results of analyses. (J.C.)

  14. Rover deployment system for lunar landing mission

    Science.gov (United States)

    Sutoh, Masataku; Hoshino, Takeshi; Wakabayashi, Sachiko

    2017-09-01

    For lunar surface exploration, a deployment system is necessary to allow a rover to leave the lander. The system should be as lightweight as possible and stored retracted when launched. In this paper, two types of retractable deployment systems for lunar landing missions, telescopic- and fold-type ramps, are discussed. In the telescopic-type system, a ramp is stored with the sections overlapping and slides out during deployment. In the fold-type system, it is stored folded and unfolds for the deployment. For the development of these ramps, a design concept study and structural analysis were conducted first. Subsequently, ramp deployment and rover release tests were performed using the developed ramp prototypes. Through these tests, the validity of their design concepts and functions have been confirmed. In the rover release test, it was observed that the developed lightweight ramp was sufficiently strong for a 50-kg rover to descend. This result suggests that this ramp system is suitable for the deployment of a 300-kg-class rover on the Moon, where the gravity is about one-sixth that on Earth. The lightweight and sturdy ramp developed in this study will contribute to both safe rover deployment and increase of lander/rover payload.

  15. Miniature field deployable terahertz source

    Science.gov (United States)

    Mayes, Mark G.

    2006-05-01

    Developments in terahertz sources include compacted electron beam systems, optical mixing techniques, and multiplication of microwave frequencies. Although significant advances in THz science have been achieved, efforts continue to obtain source technologies that are more mobile and suitable for field deployment. Strategies in source development have approached generation from either end of the THz spectrum, from up-conversion of high-frequency microwave to down-conversion of optical frequencies. In this paper, we present the design of a THz source which employs an up-conversion method in an assembly that integrates power supply, electronics, and radiative component into a man-portable unit for situations in which a lab system is not feasible. This unit will ultimately evolve into a ruggedized package suitable for use in extreme conditions, e.g. temporary security check points or emergency response teams, in conditions where THz diagnostics are needed with minimal planning or logistical support. In order to meet design goals of reduced size and complexity, the inner workings of the unit ideally would be condensed into a monolithic active element, with ancillary systems, e.g. user interface and power, coupled to the element. To attain these goals, the fundamental component of our design is a THz source and lens array that may be fabricated with either printed circuit board or wafer substrate. To reduce the volume occupied by the source array, the design employs a metamaterial composed of a periodic lattice of resonant elements. Each resonant element is an LC oscillator, or tank circuit, with inductance, capacitance, and center frequency determined by dimensioning and material parameters. The source array and supporting electronics are designed so that the radiative elements are driven in-phase to yield THz radiation with a high degree of partial coherence. Simulation indicates that the spectral width of operation may be controlled by detuning of critical dimensions

  16. Americal options analyzed differently

    NARCIS (Netherlands)

    Nieuwenhuis, J.W.

    2003-01-01

    In this note we analyze in a discrete-time context and with a finite outcome space American options starting with the idea that every tradable should be a martingale under a certain measure. We believe that in this way American options become more understandable to people with a good working

  17. Analyzing Political Television Advertisements.

    Science.gov (United States)

    Burson, George

    1992-01-01

    Presents a lesson plan to help students understand that political advertisements often mislead, lie, or appeal to emotion. Suggests that the lesson will enable students to examine political advertisements analytically. Includes a worksheet to be used by students to analyze individual political advertisements. (DK)

  18. Centrifugal analyzer development

    International Nuclear Information System (INIS)

    Burtis, C.A.; Bauer, M.L.; Bostick, W.D.

    1976-01-01

    The development of the centrifuge fast analyzer (CFA) is reviewed. The development of a miniature CFA with computer data analysis is reported and applications for automated diagnostic chemical and hematological assays are discussed. A portable CFA system with microprocessor was adapted for field assays of air and water samples for environmental pollutants, including ammonia, nitrates, nitrites, phosphates, sulfates, and silica. 83 references

  19. Shape accuracy optimization for cable-rib tension deployable antenna structure with tensioned cables

    Science.gov (United States)

    Liu, Ruiwei; Guo, Hongwei; Liu, Rongqiang; Wang, Hongxiang; Tang, Dewei; Song, Xiaoke

    2017-11-01

    Shape accuracy is of substantial importance in deployable structures as the demand for large-scale deployable structures in various fields, especially in aerospace engineering, increases. The main purpose of this paper is to present a shape accuracy optimization method to find the optimal pretensions for the desired shape of cable-rib tension deployable antenna structure with tensioned cables. First, an analysis model of the deployable structure is established by using finite element method. In this model, geometrical nonlinearity is considered for the cable element and beam element. Flexible deformations of the deployable structure under the action of cable network and tensioned cables are subsequently analyzed separately. Moreover, the influence of pretension of tensioned cables on natural frequencies is studied. Based on the results, a genetic algorithm is used to find a set of reasonable pretension and thus minimize structural deformation under the first natural frequency constraint. Finally, numerical simulations are presented to analyze the deployable structure under two kinds of constraints. Results show that the shape accuracy and natural frequencies of deployable structure can be effectively improved by pretension optimization.

  20. Spectrometric microbiological analyzer

    Science.gov (United States)

    Schlager, Kenneth J.; Meissner, Ken E.

    1996-04-01

    Currently, there are four general approaches to microbiological analysis, i.e., the detection, identification and quantification of micro-organisms: (1) Traditional culturing and staining procedures, metabolic fermentations and visual morphological characteristics; (2) Immunological approaches employing microbe-specific antibodies; (3) Biotechnical techniques employing DNA probes and related genetic engineering methods; and (4) Physical measurement techniques based on the biophysical properties of micro-organisms. This paper describes an instrumentation development in the fourth of the above categories, physical measurement, that uses a combination of fluorometric and light scatter spectra to detect and identify micro-organisms at the species level. A major advantage of this approach is the rapid turnaround possible in medical diagnostic or water testing applications. Fluorometric spectra serve to define the biochemical characteristics of the microbe, and light scatter spectra the size and shape morphology. Together, the two spectra define a 'fingerprint' for each species of microbe for detection, identification and quantification purposes. A prototype instrument has been developed and tested under NASA sponsorship based on fluorometric spectra alone. This instrument demonstrated identification and quantification capabilities at the species level. The paper reports on test results using this instrument, and the benefits of employing a combination of fluorometric and light scatter spectra.

  1. Soft Decision Analyzer

    Science.gov (United States)

    Lansdowne, Chatwin; Steele, Glen; Zucha, Joan; Schlesinger, Adam

    2013-01-01

    We describe the benefit of using closed-loop measurements for a radio receiver paired with a counterpart transmitter. We show that real-time analysis of the soft decision output of a receiver can provide rich and relevant insight far beyond the traditional hard-decision bit error rate (BER) test statistic. We describe a Soft Decision Analyzer (SDA) implementation for closed-loop measurements on single- or dual- (orthogonal) channel serial data communication links. The analyzer has been used to identify, quantify, and prioritize contributors to implementation loss in live-time during the development of software defined radios. This test technique gains importance as modern receivers are providing soft decision symbol synchronization as radio links are challenged to push more data and more protocol overhead through noisier channels, and software-defined radios (SDRs) use error-correction codes that approach Shannon's theoretical limit of performance.

  2. KWU Nuclear Plant Analyzer

    International Nuclear Information System (INIS)

    Bennewitz, F.; Hummel, R.; Oelmann, K.

    1986-01-01

    The KWU Nuclear Plant Analyzer is a real time engineering simulator based on the KWU computer programs used in plant transient analysis and licensing. The primary goal is to promote the understanding of the technical and physical processes of a nuclear power plant at an on-site training facility. Thus the KWU Nuclear Plant Analyzer is available with comparable low costs right at the time when technical questions or training needs arise. This has been achieved by (1) application of the transient code NLOOP; (2) unrestricted operator interaction including all simulator functions; (3) using the mainframe computer Control Data Cyber 176 in the KWU computing center; (4) four color graphic displays controlled by a dedicated graphic computer, no control room equipment; and (5) coupling of computers by telecommunication via telephone

  3. Analyzed Using Statistical Moments

    International Nuclear Information System (INIS)

    Oltulu, O.

    2004-01-01

    Diffraction enhanced imaging (DEl) technique is a new x-ray imaging method derived from radiography. The method uses a monorheumetten x-ray beam and introduces an analyzer crystal between an object and a detector Narrow angular acceptance of the analyzer crystal generates an improved contrast over the evaluation radiography. While standart radiography can produce an 'absorption image', DEl produces 'apparent absorption' and 'apparent refraction' images with superior quality. Objects with similar absorption properties may not be distinguished with conventional techniques due to close absorption coefficients. This problem becomes more dominant when an object has scattering properties. A simple approach is introduced to utilize scattered radiation to obtain 'pure absorption' and 'pure refraction' images

  4. MICROSATELLITE GENOTYPING USING THE BASESTATION DNA FRAGMENT ANALYZER. (R826603)

    Science.gov (United States)

    The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Concl...

  5. Scalable Parallel Methods for Analyzing Metagenomics Data at Extreme Scale

    International Nuclear Information System (INIS)

    Daily, Jeffrey A.

    2015-01-01

    The field of bioinformatics and computational biology is currently experiencing a data revolution. The exciting prospect of making fundamental biological discoveries is fueling the rapid development and deployment of numerous cost-effective, high-throughput next-generation sequencing technologies. The result is that the DNA and protein sequence repositories are being bombarded with new sequence information. Databases are continuing to report a Moore's law-like growth trajectory in their database sizes, roughly doubling every 18 months. In what seems to be a paradigm-shift, individual projects are now capable of generating billions of raw sequence data that need to be analyzed in the presence of already annotated sequence information. While it is clear that data-driven methods, such as sequencing homology detection, are becoming the mainstay in the field of computational life sciences, the algorithmic advancements essential for implementing complex data analytics at scale have mostly lagged behind. Sequence homology detection is central to a number of bioinformatics applications including genome sequencing and protein family characterization. Given millions of sequences, the goal is to identify all pairs of sequences that are highly similar (or 'homologous') on the basis of alignment criteria. While there are optimal alignment algorithms to compute pairwise homology, their deployment for large-scale is currently not feasible; instead, heuristic methods are used at the expense of quality. In this dissertation, we present the design and evaluation of a parallel implementation for conducting optimal homology detection on distributed memory supercomputers. Our approach uses a combination of techniques from asynchronous load balancing (viz. work stealing, dynamic task counters), data replication, and exact-matching filters to achieve homology detection at scale. Results for a collection of 2.56M sequences show parallel efficiencies of ~75-100% on up to 8K

  6. Scalable Parallel Methods for Analyzing Metagenomics Data at Extreme Scale

    Energy Technology Data Exchange (ETDEWEB)

    Daily, Jeffrey A. [Washington State Univ., Pullman, WA (United States)

    2015-05-01

    The field of bioinformatics and computational biology is currently experiencing a data revolution. The exciting prospect of making fundamental biological discoveries is fueling the rapid development and deployment of numerous cost-effective, high-throughput next-generation sequencing technologies. The result is that the DNA and protein sequence repositories are being bombarded with new sequence information. Databases are continuing to report a Moore’s law-like growth trajectory in their database sizes, roughly doubling every 18 months. In what seems to be a paradigm-shift, individual projects are now capable of generating billions of raw sequence data that need to be analyzed in the presence of already annotated sequence information. While it is clear that data-driven methods, such as sequencing homology detection, are becoming the mainstay in the field of computational life sciences, the algorithmic advancements essential for implementing complex data analytics at scale have mostly lagged behind. Sequence homology detection is central to a number of bioinformatics applications including genome sequencing and protein family characterization. Given millions of sequences, the goal is to identify all pairs of sequences that are highly similar (or “homologous”) on the basis of alignment criteria. While there are optimal alignment algorithms to compute pairwise homology, their deployment for large-scale is currently not feasible; instead, heuristic methods are used at the expense of quality. In this dissertation, we present the design and evaluation of a parallel implementation for conducting optimal homology detection on distributed memory supercomputers. Our approach uses a combination of techniques from asynchronous load balancing (viz. work stealing, dynamic task counters), data replication, and exact-matching filters to achieve homology detection at scale. Results for a collection of 2.56M sequences show parallel efficiencies of ~75-100% on up to 8K cores

  7. Emission spectrometric isotope analyzer

    International Nuclear Information System (INIS)

    Mauersberger, K.; Meier, G.; Nitschke, W.; Rose, W.; Schmidt, G.; Rahm, N.; Andrae, G.; Krieg, D.; Kuefner, W.; Tamme, G.; Wichlacz, D.

    1982-01-01

    An emission spectrometric isotope analyzer has been designed for determining relative abundances of stable isotopes in gaseous samples in discharge tubes, in liquid samples, and in flowing gaseous samples. It consists of a high-frequency generator, a device for defined positioning of discharge tubes, a grating monochromator with oscillating slit and signal converter, signal generator, window discriminator, AND connection, read-out display, oscillograph, gas dosing device and chemical conversion system with carrier gas source and vacuum pump

  8. Project implementation plan: ASTD remote deployment

    International Nuclear Information System (INIS)

    CRASS, D.W.

    1999-01-01

    This document is the project implementation plan for the ASTD Remote Deployment Project. The Plan identifies the roles and responsibilities for the project and defines the integration between the ASTD Project and the B-Cell Cleanout Project

  9. Office of Civilian Response Deployment Tracking System

    Data.gov (United States)

    US Agency for International Development — The purpose of OCR DTS is to establish, manage and track relevant Civilian Response Corps teams for deployment by sector experience, training, education etc.

  10. RadNet Air Quality (Deployable) Data

    Data.gov (United States)

    U.S. Environmental Protection Agency — RadNet Deployable Monitoring is designed to collect radiological and meteorological information and data asset needed to establish the impact of radiation levels on...

  11. Self-Deploying, Composite Habitats, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — Cornerstone Research Group, Inc. (CRG), proposes to develop self-deploying, composite structures for lunar habitats, based on CRG's VeritexTM materials. These...

  12. Small cell networks deployment, management, and optimization

    CERN Document Server

    Claussen, Holger; Ho, Lester; Razavi, Rouzbeh; Kucera, Stepan

    2018-01-01

    Small Cell Networks: Deployment, Management, and Optimization addresses key problems of the cellular network evolution towards HetNets. It focuses on the latest developments in heterogeneous and small cell networks, as well as their deployment, operation, and maintenance. It also covers the full spectrum of the topic, from academic, research, and business to the practice of HetNets in a coherent manner. Additionally, it provides complete and practical guidelines to vendors and operators interested in deploying small cells. The first comprehensive book written by well-known researchers and engineers from Nokia Bell Labs, Small Cell Networks begins with an introduction to the subject--offering chapters on capacity scaling and key requirements of future networks. It then moves on to sections on coverage and capacity optimization, and interference management. From there, the book covers mobility management, energy efficiency, and small cell deployment, ending with a section devoted to future trends and applicat...

  13. Community integration after deployment to Afghanistan

    DEFF Research Database (Denmark)

    Karstoft, Karen-Inge; Armour, Cherie; Andersen, Søren B.

    2015-01-01

    OBJECTIVE: In the years following military deployment, soldiers may experience problems integrating into the community. However, little is known about the nature and prevalence of these problems and if they relate to posttraumatic symptomatology. METHODS: In a prospective, longitudinal study...

  14. Deployment strategies of managed lanes on arterials.

    Science.gov (United States)

    2015-02-01

    This report investigates issues related to planning, financing, deployment, and operation of managed : lanes on arterials. In this report, a strategy for managed lanes refers to a combination of the managed : lane type, the design and implementation,...

  15. Deploying Missile Defense: Major Operational Challenges

    National Research Council Canada - National Science Library

    Bunn, M

    2004-01-01

    By October 2004, the United States will have begun initial deployment of a missile defense capability albeit a modest, limited, and not completely proven one to defend the homeland against a limited...

  16. Deployable structures for a human lunar base

    Science.gov (United States)

    Gruber, Petra; Häuplik, Sandra; Imhof, Barbara; Özdemir, Kürsad; Waclavicek, Rene; Perino, Maria Antoinetta

    2007-06-01

    The study Lunar exploration architecture—deployable structures for a lunar base was performed within the Alcatel Alenia Space “Lunar Exploration Architecture” study for the European Space Agency. The purpose of the study was to investigate bionic concepts applicable to deployable structures and to interpret the findings for possible implementation concepts. The study aimed at finding innovative solutions for deployment possibilities. Translating folding/unfolding principles from nature, candidate geometries were developed and researched using models, drawings and visualisations. The use of materials, joints between structural elements and construction details were investigated for these conceptual approaches. Reference scenarios were used to identify the technical and environmental conditions, which served as design drivers. Mechanical issues and the investigation of deployment processes narrowed the selection down to six chosen concepts. Their applicability was evaluated at a conceptual stage in relation to the timescale of the mission.

  17. Military Families: Child Care Support During Deployments

    Science.gov (United States)

    ... temporary caregiver far in advance will make your children feel more secure. Try to have the caregiver connect prior to deployment through visits, phone calls, or social media. If you will be relocating to a family ...

  18. Concept of Deployable Network Operations Center (DNOC)

    National Research Council Canada - National Science Library

    Bordetsky, Alex; Thiry, Jeff; Johnson, Shawn

    2005-01-01

    .... The increasing use of expeditionary and special operations forces in ad hoc, dynamic, and tactical environments poses a need for an adaptable, flexible, and responsive deployable network operations center (DNOC...

  19. In-Flight Suppressant Deployment Temperatures

    National Research Council Canada - National Science Library

    Bein, Donald

    2006-01-01

    .... An assessment is made of the model output versus some aircraft measurement data, fire suppressant boiling point criterion, as well as the history of altitude/temperature at which fire suppressants have been deployed...

  20. Demonstration and Deployment Strategy Workshop: Summary

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2014-05-01

    This report is based on the proceedings of the U.S. Department of Energy Bioenergy Technologies Office Demonstration and Deployment Strategy Workshop, held on March 12–13, 2014, at Argonne National Laboratory.

  1. A Novel Methodology for Charging Station Deployment

    Science.gov (United States)

    Sun, Zhonghao; Zhao, Yunwei; He, Yueying; Li, Mingzhe

    2018-02-01

    Lack of charging stations has been a main obstacle to the promotion of electric vehicles. This paper studies deploying charging stations in traffic networks considering grid constraints to balance the charging demand and grid stability. First, we propose a statistical model for charging demand. Then we combine the charging demand model with power grid constraints and give the formulation of the charging station deployment problem. Finally, we propose a theoretical solution for the problem by transforming it to a Markov Decision Process.

  2. State perspectives on clean coal technology deployment

    Energy Technology Data Exchange (ETDEWEB)

    Moreland, T. [State of Illinois Washington Office, Washington, DC (United States)

    1997-12-31

    State governments have been funding partners in the Clean Coal Technology program since its beginnings. Today, regulatory and market uncertainties and tight budgets have reduced state investment in energy R and D, but states have developed program initiatives in support of deployment. State officials think that the federal government must continue to support these technologies in the deployment phase. Discussions of national energy policy must include attention to the Clean Coal Technology program and its accomplishments.

  3. DRAGON - 8U Nanosatellite Orbital Deployer

    Science.gov (United States)

    Dobrowolski, Marcin; Grygorczuk, Jerzy; Kedziora, Bartosz; Tokarz, Marta; Borys, Maciej

    2014-01-01

    The Space Research Centre of the Polish Academy of Sciences (SRC PAS) together with Astronika company have developed an Orbital Deployer called DRAGON for ejection of the Polish scientific nanosatellite BRITE-PL Heweliusz (Fig. 1). The device has three unique mechanisms including an adopted and scaled lock and release mechanism from the ESA Rosetta mission MUPUS instrument. This paper discusses major design restrictions of the deployer, unique design features, and lessons learned from development through testing.

  4. Deploying Renewables - Best and Future Policy Practice

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-11-23

    The global energy system faces urgent challenges. Concerns about energy security are growing, as highlighted by the recent political turmoil in Northern Africa and the nuclear incident in Fukushima. At the same time, the need to respond to climate change is more critical than ever. Against this background, many governments have increased efforts to promote deployment of renewable energy -- low-carbon sources that can strengthen energy security. This has stimulated unprecedented rise in deployment, and renewables are now the fastest growing sector of the energy mix. This 'coming of age' of renewable energy also brings challenges. Growth is focused on a few of the available technologies, and rapid deployment is confined to a relatively small number of countries. In more advanced markets, managing support costs and system integration of large shares of renewable energy in a time of economic weakness and budget austerity has sparked vigorous political debate. The IEA's new report, Deploying Renewables 2011: Best and Future Policy Practice: - Provides a comprehensive review and analysis of renewable energy policy and market trends; - Analyses in detail the dynamics of deployment and provides best-practice policy principles for different stages of market maturity; - Assesses the impact and cost-effectiveness of support policies using new methodological tools and indicators; - Investigates the strategic reasons underpinning the pursuit of RE deployment by different countries and the prospects for globalisation of RE. This new book builds on and extends a 2008 IEA publication, drawing on recent policy and deployment experience world-wide. It provides guidance for policy makers and other stakeholders to avoid past mistakes, overcome new challenges and reap the benefits of deploying renewables -- today and tomorrow.

  5. A stowing and deployment strategy for large membrane space systems on the example of Gossamer-1

    Science.gov (United States)

    Seefeldt, Patric

    2017-09-01

    Deployment systems for innovative space applications such as solar sails require a technique for a controlled and autonomous deployment in space. The deployment process has a strong impact on the mechanism and structural design and sizing. On the example of the design implemented in the Gossamer-1 project of the German Aerospace Center (DLR), such a stowing and deployment process is analyzed. It is based on a combination of zig-zag folding and coiling of triangular sail segments spanned between crossed booms. The deployment geometry and forces introduced by the mechanism considered are explored in order to reveal how the loads are transferred through the membranes to structural components such as the booms. The folding geometry and force progressions are described by function compositions of an inverse trigonometric function with the considered trigonometric function itself. If these functions are evaluated over several periods of the trigonometric function, a non-smooth oscillating curve occurs. Depending on the trigonometric function, these are often vividly described as zig-zag or sawtooth functions. The developed functions are applied to the Gossamer-1 design. The deployment geometry reveals a tendency that the loads are transferred along the catheti of the sail segments and therefore mainly along the boom axes. The load introduced by the spool deployment mechanism is described. By combining the deployment geometry with that load, a prediction of the deployment load progression is achieved. The mathematical description of the stowing and deployment geometry, as well as the forces inflicted by the mechanism provides an understanding of how exactly the membrane deploys and through which edges the deployment forces are transferred. The mathematical analysis also gives an impression of sensitive parameters that could be influenced by manufacturing tolerances or unsymmetrical deployment of the sail segments. While the mathematical model was applied on the design of

  6. PhosphoSiteAnalyzer

    DEFF Research Database (Denmark)

    Bennetzen, Martin V; Cox, Jürgen; Mann, Matthias

    2012-01-01

    an algorithm to retrieve kinase predictions from the public NetworKIN webpage in a semiautomated way and applies hereafter advanced statistics to facilitate a user-tailored in-depth analysis of the phosphoproteomic data sets. The interface of the software provides a high degree of analytical flexibility......Phosphoproteomic experiments are routinely conducted in laboratories worldwide, and because of the fast development of mass spectrometric techniques and efficient phosphopeptide enrichment methods, researchers frequently end up having lists with tens of thousands of phosphorylation sites...... and is designed to be intuitive for most users. PhosphoSiteAnalyzer is a freeware program available at http://phosphosite.sourceforge.net ....

  7. Electrodynamic thermogravimetric analyzer

    International Nuclear Information System (INIS)

    Spjut, R.E.; Bar-Ziv, E.; Sarofim, A.F.; Longwell, J.P.

    1986-01-01

    The design and operation of a new device for studying single-aerosol-particle kinetics at elevated temperatures, the electrodynamic thermogravimetric analyzer (EDTGA), was examined theoretically and experimentally. The completed device consists of an electrodynamic balance modified to permit particle heating by a CO 2 laser, temperature measurement by a three-color infrared-pyrometry system, and continuous weighing by a position-control system. In this paper, the position-control, particle-weight-measurement, heating, and temperature-measurement systems are described and their limitations examined

  8. Analyzing Chinese Financial Reporting

    Institute of Scientific and Technical Information of China (English)

    SABRINA; ZHANG

    2008-01-01

    If the world’s capital markets could use a harmonized accounting framework it would not be necessary for a comparison between two or more sets of accounting standards. However,there is much to do before this becomes reality.This article aims to pres- ent a general overview of China’s General Accepted Accounting Principles(GAAP), U.S.General Accepted Accounting Principles and International Financial Reporting Standards(IFRS),and to analyze the differ- ences among IFRS,U.S.GAAP and China GAAP using fixed assets as an example.

  9. Inductive dielectric analyzer

    International Nuclear Information System (INIS)

    Agranovich, Daniel; Popov, Ivan; Ben Ishai, Paul; Feldman, Yuri; Polygalov, Eugene

    2017-01-01

    One of the approaches to bypass the problem of electrode polarization in dielectric measurements is the free electrode method. The advantage of this technique is that, the probing electric field in the material is not supplied by contact electrodes, but rather by electromagnetic induction. We have designed an inductive dielectric analyzer based on a sensor comprising two concentric toroidal coils. In this work, we present an analytic derivation of the relationship between the impedance measured by the sensor and the complex dielectric permittivity of the sample. The obtained relationship was successfully employed to measure the dielectric permittivity and conductivity of various alcohols and aqueous salt solutions. (paper)

  10. Analyzing public health policy: three approaches.

    Science.gov (United States)

    Coveney, John

    2010-07-01

    Policy is an important feature of public and private organizations. Within the field of health as a policy arena, public health has emerged in which policy is vital to decision making and the deployment of resources. Public health practitioners and students need to be able to analyze public health policy, yet many feel daunted by the subject's complexity. This article discusses three approaches that simplify policy analysis: Bacchi's "What's the problem?" approach examines the way that policy represents problems. Colebatch's governmentality approach provides a way of analyzing the implementation of policy. Bridgman and Davis's policy cycle allows for an appraisal of public policy development. Each approach provides an analytical framework from which to rigorously study policy. Practitioners and students of public health gain much in engaging with the politicized nature of policy, and a simple approach to policy analysis can greatly assist one's understanding and involvement in policy work.

  11. Plutonium solution analyzer

    International Nuclear Information System (INIS)

    Burns, D.A.

    1994-09-01

    A fully automated analyzer has been developed for plutonium solutions. It was assembled from several commercially available modules, is based upon segmented flow analysis, and exhibits precision about an order of magnitude better than commercial units (0.5%-O.05% RSD). The system was designed to accept unmeasured, untreated liquid samples in the concentration range 40-240 g/L and produce a report with sample identification, sample concentrations, and an abundance of statistics. Optional hydraulics can accommodate samples in the concentration range 0.4-4.0 g/L. Operating at a typical rate of 30 to 40 samples per hour, it consumes only 0.074 mL of each sample and standard, and generates waste at the rate of about 1.5 mL per minute. No radioactive material passes through its multichannel peristaltic pump (which remains outside the glovebox, uncontaminated) but rather is handled by a 6-port, 2-position chromatography-type loop valve. An accompanying computer is programmed in QuickBASIC 4.5 to provide both instrument control and data reduction. The program is truly user-friendly and communication between operator and instrument is via computer screen displays and keyboard. Two important issues which have been addressed are waste minimization and operator safety (the analyzer can run in the absence of an operator, once its autosampler has been loaded)

  12. Multiple capillary biochemical analyzer

    Science.gov (United States)

    Dovichi, N.J.; Zhang, J.Z.

    1995-08-08

    A multiple capillary analyzer allows detection of light from multiple capillaries with a reduced number of interfaces through which light must pass in detecting light emitted from a sample being analyzed, using a modified sheath flow cuvette. A linear or rectangular array of capillaries is introduced into a rectangular flow chamber. Sheath fluid draws individual sample streams through the cuvette. The capillaries are closely and evenly spaced and held by a transparent retainer in a fixed position in relation to an optical detection system. Collimated sample excitation radiation is applied simultaneously across the ends of the capillaries in the retainer. Light emitted from the excited sample is detected by the optical detection system. The retainer is provided by a transparent chamber having inward slanting end walls. The capillaries are wedged into the chamber. One sideways dimension of the chamber is equal to the diameter of the capillaries and one end to end dimension varies from, at the top of the chamber, slightly greater than the sum of the diameters of the capillaries to, at the bottom of the chamber, slightly smaller than the sum of the diameters of the capillaries. The optical system utilizes optic fibers to deliver light to individual photodetectors, one for each capillary tube. A filter or wavelength division demultiplexer may be used for isolating fluorescence at particular bands. 21 figs.

  13. Plutonium solution analyzer

    Energy Technology Data Exchange (ETDEWEB)

    Burns, D.A.

    1994-09-01

    A fully automated analyzer has been developed for plutonium solutions. It was assembled from several commercially available modules, is based upon segmented flow analysis, and exhibits precision about an order of magnitude better than commercial units (0.5%-O.05% RSD). The system was designed to accept unmeasured, untreated liquid samples in the concentration range 40-240 g/L and produce a report with sample identification, sample concentrations, and an abundance of statistics. Optional hydraulics can accommodate samples in the concentration range 0.4-4.0 g/L. Operating at a typical rate of 30 to 40 samples per hour, it consumes only 0.074 mL of each sample and standard, and generates waste at the rate of about 1.5 mL per minute. No radioactive material passes through its multichannel peristaltic pump (which remains outside the glovebox, uncontaminated) but rather is handled by a 6-port, 2-position chromatography-type loop valve. An accompanying computer is programmed in QuickBASIC 4.5 to provide both instrument control and data reduction. The program is truly user-friendly and communication between operator and instrument is via computer screen displays and keyboard. Two important issues which have been addressed are waste minimization and operator safety (the analyzer can run in the absence of an operator, once its autosampler has been loaded).

  14. Simulating CubeSat Structure Deployment Dynamics, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — There is high value in simulating the nonlinear dynamics of stowing, deploying, and performance of deployable space structures, especially given the profound...

  15. Dynamic characteristics analysis of deployable space structures considering joint clearance

    Science.gov (United States)

    Li, Tuanjie; Guo, Jian; Cao, Yuyan

    2011-04-01

    The clearance in joints influences the dynamic stability and the performance of deployable space structures (DSS). A virtual experimental modal analysis (VEMA) method is proposed to deal with the effects of joint clearance and link flexibility on the dynamic characteristics of the DSS in this paper. The focus is on the finite element modeling of the clearance joint, VEMA and the modal parameters identification of the DSS. The finite element models (FEM) of the clearance joint and the deployable structure are established in ANSYS. The transient dynamic analysis is conducted to provide the time history data of excitation and response for the VEMA. The fast Fourier transform (FFT) technique is used to transform the data from time domain to frequency domain. The frequency response function is calculated to identify the modal parameters of the deployable structure. Experimental verification is provided to indicate the VEMA method is both a cost and time efficient approach to obtain the dynamic characteristics of the DSS. Finally, we analyze the effects of clearance size and gravity on the dynamic characteristics of the DSS. The analysis results indicate that the joint clearance and gravity strongly influence the dynamic characteristics of the DSS.

  16. Trace impurity analyzer

    International Nuclear Information System (INIS)

    Schneider, W.J.; Edwards, D. Jr.

    1979-01-01

    The desirability for long-term reliability of large scale helium refrigerator systems used on superconducting accelerator magnets has necessitated detection of impurities to levels of a few ppM. An analyzer that measures trace impurity levels of condensable contaminants in concentrations of less than a ppM in 15 atm of He is described. The instrument makes use of the desorption temperature at an indicated pressure of the various impurities to determine the type of contaminant. The pressure rise at that temperature yields a measure of the contaminant level of the impurity. A LN 2 cryogenic charcoal trap is also employed to measure air impurities (nitrogen and oxygen) to obtain the full range of contaminant possibilities. The results of this detector which will be in use on the research and development helium refrigerator of the ISABELLE First-Cell is described

  17. Analyzing Water's Optical Absorption

    Science.gov (United States)

    2002-01-01

    A cooperative agreement between World Precision Instruments (WPI), Inc., and Stennis Space Center has led the UltraPath(TM) device, which provides a more efficient method for analyzing the optical absorption of water samples at sea. UltraPath is a unique, high-performance absorbance spectrophotometer with user-selectable light path lengths. It is an ideal tool for any study requiring precise and highly sensitive spectroscopic determination of analytes, either in the laboratory or the field. As a low-cost, rugged, and portable system capable of high- sensitivity measurements in widely divergent waters, UltraPath will help scientists examine the role that coastal ocean environments play in the global carbon cycle. UltraPath(TM) is a trademark of World Precision Instruments, Inc. LWCC(TM) is a trademark of World Precision Instruments, Inc.

  18. Information decomposition method to analyze symbolical sequences

    International Nuclear Information System (INIS)

    Korotkov, E.V.; Korotkova, M.A.; Kudryashov, N.A.

    2003-01-01

    The information decomposition (ID) method to analyze symbolical sequences is presented. This method allows us to reveal a latent periodicity of any symbolical sequence. The ID method is shown to have advantages in comparison with application of the Fourier transformation, the wavelet transform and the dynamic programming method to look for latent periodicity. Examples of the latent periods for poetic texts, DNA sequences and amino acids are presented. Possible origin of a latent periodicity for different symbolical sequences is discussed

  19. Modeling DNA

    Science.gov (United States)

    Robertson, Carol

    2016-01-01

    Deoxyribonucleic acid (DNA) is life's most amazing molecule. It carries the genetic instructions that almost every organism needs to develop and reproduce. In the human genome alone, there are some three billion DNA base pairs. The most difficult part of teaching DNA structure, however, may be getting students to visualize something as small as a…

  20. A Remotely Deployable Wind Sonic Anemometer

    Directory of Open Access Journals (Sweden)

    Muhammad Awais

    2017-12-01

    Full Text Available Communication and computing shape up base for explosion of Internet of Things (IoT era. Humans can efficiently control the devices around their environment as per requirements because of IoT, the communication between different devices brings more flexibility in surrounding. Useful data is also gathered from some of these devices to create Big Data; where, further analysis assist in making life easier by developing good business models corresponding to user needs, enhance scientific research, formulating weather prediction or monitoring systems and contributing in other relative fields as well. Thus, in this research a remotely deployable IoT enabled Wind Sonic Anemometer has been designed and deployed to calculate average wind speed, direction, and gust. The proposed design is remotely deployable, user-friendly, power efficient and cost-effective because of opted modules i.e., ultrasonic sensors, GSM module, and solar panel. The testbed was also deployed at the roof of Computer & Information Systems Engineering (CIS department, NED UET. Further, its calibration has been carried out by using long short-term memory (LSTM, a deep learning technique; where ground truth data has been gathered from mechanical wind speed sensor (NRG-40 H deployed at top of Industrial & Manufacturing (IM department of NED UET. The obtained results are satisfactory and the performance of designed sensor is also good under various weather conditions.

  1. Environmental issues affecting clean coal technology deployment

    Energy Technology Data Exchange (ETDEWEB)

    Miller, M.J. [Electric Power Research Inst., Palo Alto, CA (United States)

    1997-12-31

    The author outlines what he considers to be the key environmental issues affecting Clean Coal Technology (CCT) deployment both in the US and internationally. Since the international issues are difficult to characterize given different environmental drivers in various countries and regions, the primary focus of his remarks is on US deployment. However, he makes some general remarks, particularly regarding the environmental issues in developing vs. developed countries and how these issues may affect CCT deployment. Further, how environment affects deployment depends on which particular type of clean coal technology one is addressing. It is not the author`s intention to mention many specific technologies other than to use them for the purposes of example. He generally categorizes CCTs into four groups since environment is likely to affect deployment for each category somewhat differently. These four categories are: Precombustion technologies such as coal cleaning; Combustion technologies such as low NOx burners; Postcombustion technologies such as FGD systems and postcombustion NOx control; and New generation technologies such as gasification and fluidized bed combustion.

  2. A neutron activation analyzer

    International Nuclear Information System (INIS)

    Westphal, G.P.; Lemmel, H.; Grass, F.; De Regge, P.P.; Burns, K.; Markowicz, A.

    2005-01-01

    Dubbed 'Analyzer' because of its simplicity, a neutron activation analysis facility for short-lived isomeric transitions is based on a low-cost rabbit system and an adaptive digital filter which are controlled by a software performing irradiation control, loss-free gamma-spectrometry, spectra evaluation, nuclide identification and calculation of concentrations in a fully automatic flow of operations. Designed for TRIGA reactors and constructed from inexpensive plastic tubing and an aluminum in-core part, the rabbit system features samples of 5 ml and 10 ml with sample separation at 150 ms and 200 ms transport time or 25 ml samples without separation at a transport time of 300 ms. By automatically adapting shaping times to pulse intervals the preloaded digital filter gives best throughput at best resolution up to input counting rates of 10 6 cps. Loss-free counting enables quantitative correction of counting losses of up to 99%. As a test of system reproducibility in sample separation geometry, K, Cl, Mn, Mg, Ca, Sc, and V have been determined in various reference materials at excellent agreement with consensus values. (author)

  3. Downhole Fluid Analyzer Development

    Energy Technology Data Exchange (ETDEWEB)

    Bill Turner

    2006-11-28

    A novel fiber optic downhole fluid analyzer has been developed for operation in production wells. This device will allow real-time determination of the oil, gas and water fractions of fluids from different zones in a multizone or multilateral completion environment. The device uses near infrared spectroscopy and induced fluorescence measurement to unambiguously determine the oil, water and gas concentrations at all but the highest water cuts. The only downhole components of the system are the fiber optic cable and windows. All of the active components--light sources, sensors, detection electronics and software--will be located at the surface, and will be able to operate multiple downhole probes. Laboratory testing has demonstrated that the sensor can accurately determine oil, water and gas fractions with a less than 5 percent standard error. Once installed in an intelligent completion, this sensor will give the operating company timely information about the fluids arising from various zones or multilaterals in a complex completion pattern, allowing informed decisions to be made on controlling production. The research and development tasks are discussed along with a market analysis.

  4. Climate Model Diagnostic Analyzer

    Science.gov (United States)

    Lee, Seungwon; Pan, Lei; Zhai, Chengxing; Tang, Benyang; Kubar, Terry; Zhang, Zia; Wang, Wei

    2015-01-01

    The comprehensive and innovative evaluation of climate models with newly available global observations is critically needed for the improvement of climate model current-state representation and future-state predictability. A climate model diagnostic evaluation process requires physics-based multi-variable analyses that typically involve large-volume and heterogeneous datasets, making them both computation- and data-intensive. With an exploratory nature of climate data analyses and an explosive growth of datasets and service tools, scientists are struggling to keep track of their datasets, tools, and execution/study history, let alone sharing them with others. In response, we have developed a cloud-enabled, provenance-supported, web-service system called Climate Model Diagnostic Analyzer (CMDA). CMDA enables the physics-based, multivariable model performance evaluations and diagnoses through the comprehensive and synergistic use of multiple observational data, reanalysis data, and model outputs. At the same time, CMDA provides a crowd-sourcing space where scientists can organize their work efficiently and share their work with others. CMDA is empowered by many current state-of-the-art software packages in web service, provenance, and semantic search.

  5. Analyzing Visibility Configurations.

    Science.gov (United States)

    Dachsbacher, C

    2011-04-01

    Many algorithms, such as level of detail rendering and occlusion culling methods, make decisions based on the degree of visibility of an object, but do not analyze the distribution, or structure, of the visible and occluded regions across surfaces. We present an efficient method to classify different visibility configurations and show how this can be used on top of existing methods based on visibility determination. We adapt co-occurrence matrices for visibility analysis and generalize them to operate on clusters of triangular surfaces instead of pixels. We employ machine learning techniques to reliably classify the thus extracted feature vectors. Our method allows perceptually motivated level of detail methods for real-time rendering applications by detecting configurations with expected visual masking. We exemplify the versatility of our method with an analysis of area light visibility configurations in ray tracing and an area-to-area visibility analysis suitable for hierarchical radiosity refinement. Initial results demonstrate the robustness, simplicity, and performance of our method in synthetic scenes, as well as real applications.

  6. Integrated Model to Assess Cloud Deployment Effectiveness When Developing an IT-strategy

    Science.gov (United States)

    Razumnikov, S.; Prankevich, D.

    2016-04-01

    Developing an IT-strategy of cloud deployment is a complex issue since even the stage of its formation necessitates revealing what applications will be the best possible to meet the requirements of a company business-strategy, evaluate reliability and safety of cloud providers and analyze staff satisfaction. A system of criteria, as well an integrated model to assess cloud deployment effectiveness is offered. The model makes it possible to identify what applications being at the disposal of a company, as well as new tools to be deployed are reliable and safe enough for implementation in the cloud environment. The data on practical use of the procedure to assess cloud deployment effectiveness by a provider of telecommunication services is presented. The model was used to calculate values of integral indexes of services to be assessed, then, ones, meeting the criteria and answering the business-strategy of a company, were selected.

  7. A Novel Deployment Scheme Based on Three-Dimensional Coverage Model for Wireless Sensor Networks

    Science.gov (United States)

    Xiao, Fu; Yang, Yang; Wang, Ruchuan; Sun, Lijuan

    2014-01-01

    Coverage pattern and deployment strategy are directly related to the optimum allocation of limited resources for wireless sensor networks, such as energy of nodes, communication bandwidth, and computing power, and quality improvement is largely determined by these for wireless sensor networks. A three-dimensional coverage pattern and deployment scheme are proposed in this paper. Firstly, by analyzing the regular polyhedron models in three-dimensional scene, a coverage pattern based on cuboids is proposed, and then relationship between coverage and sensor nodes' radius is deduced; also the minimum number of sensor nodes to maintain network area's full coverage is calculated. At last, sensor nodes are deployed according to the coverage pattern after the monitor area is subdivided into finite 3D grid. Experimental results show that, compared with traditional random method, sensor nodes number is reduced effectively while coverage rate of monitor area is ensured using our coverage pattern and deterministic deployment scheme. PMID:25045747

  8. Digital Microfluidics Sample Analyzer

    Science.gov (United States)

    Pollack, Michael G.; Srinivasan, Vijay; Eckhardt, Allen; Paik, Philip Y.; Sudarsan, Arjun; Shenderov, Alex; Hua, Zhishan; Pamula, Vamsee K.

    2010-01-01

    Three innovations address the needs of the medical world with regard to microfluidic manipulation and testing of physiological samples in ways that can benefit point-of-care needs for patients such as premature infants, for which drawing of blood for continuous tests can be life-threatening in their own right, and for expedited results. A chip with sample injection elements, reservoirs (and waste), droplet formation structures, fluidic pathways, mixing areas, and optical detection sites, was fabricated to test the various components of the microfluidic platform, both individually and in integrated fashion. The droplet control system permits a user to control droplet microactuator system functions, such as droplet operations and detector operations. Also, the programming system allows a user to develop software routines for controlling droplet microactuator system functions, such as droplet operations and detector operations. A chip is incorporated into the system with a controller, a detector, input and output devices, and software. A novel filler fluid formulation is used for the transport of droplets with high protein concentrations. Novel assemblies for detection of photons from an on-chip droplet are present, as well as novel systems for conducting various assays, such as immunoassays and PCR (polymerase chain reaction). The lab-on-a-chip (a.k.a., lab-on-a-printed-circuit board) processes physiological samples and comprises a system for automated, multi-analyte measurements using sub-microliter samples of human serum. The invention also relates to a diagnostic chip and system including the chip that performs many of the routine operations of a central labbased chemistry analyzer, integrating, for example, colorimetric assays (e.g., for proteins), chemiluminescence/fluorescence assays (e.g., for enzymes, electrolytes, and gases), and/or conductometric assays (e.g., for hematocrit on plasma and whole blood) on a single chip platform.

  9. Service Creation and Deployment in Converged Networks

    DEFF Research Database (Denmark)

    Soler, José

    for these experiences is the transition of telecommunication (telephony) networks from circuit switched based systems towards packet based ones. The text of this monograph proceeds, unaltered for the most, from the author’s PhD thesis “Framework for Deployment of Advanced Telecommunication Services in Current......This monograph (Early Experiences related to Service Creation & Deployment in Converged Networks) presents different experiences related to architectures and mechanisms for deployment of telephony services, understood as especial features complementing the basic voice service. The context...... and Future Converged Networks”, carried out at the Technical University of Denmark in the period [April 2002-April 2005]. Even though the technologies presented in the text have evolved from that period until now, the presented scenarios and setups are still valid as interesting initial steps in the realm....

  10. Deploying Embodied AI into Virtual Worlds

    Science.gov (United States)

    Burden, David J. H.

    The last two years have seen the start of commercial activity within virtual worlds. Unlike computer games where Non-Player-Character avatars are common, in most virtual worlds they are the exception — and until recently in Second Life they were non-existent. However there is real commercial scope for Als in these worlds — in roles from virtual sales staff and tutors to personal assistants. Deploying an embodied AI into a virtual world offers a unique opportunity to evaluate embodied Als, and to develop them within an environment where human and computer are on almost equal terms. This paper presents an architecture being used for the deployment of chatbot driven avatars within the Second Life virtual world, looks at the challenges of deploying an AI within such a virtual world, the possible implications for the Turing Test, and identifies research directions for the future.

  11. Deployment Instabilities of Lobed-Pumpkin Balloon

    Science.gov (United States)

    Nakashino, Kyoichi

    A lobed-pumpkin balloon, currently being developed in ISAS/JAXA as well as in NASA, is a promising vehicle for long duration scientific observations in the stratosphere. Recent ground and flight experiments, however, have revealed that the balloon has deployment instabilities under certain conditions. In order to overcome the instability problems, a next generation SPB called 'tawara' type balloon has been proposed, in which an additional cylindrical part is appended to the standard lobed-pumpkin balloon. The present study investigates the deployment stability of tawara type SPB in comparison to that of standard lobed-pumpkin SPB through eigenvalue analysis on the basis of finite element methods. Our numerical results show that tawara type SPB enjoys excellent deployment performance over the standard lobed-pumpkin SPBs.

  12. Hard is Normal: Military Families' Transitions Within the Process of Deployment.

    Science.gov (United States)

    Yablonsky, Abigail M; Barbero, Edie Devers; Richardson, Jeanita W

    2016-02-01

    US military deployments have become more frequent and lengthier in duration since 2003. Over half of US military members are married, and many also have children. The authors sought to understand the process of deployment from the perspective of the military family. After a thorough search of the literature, 21 primary research reports of 19 studies with an aggregate sample of 874 were analyzed using qualitative metasynthesis. The deployment process was experienced in four temporal domains. The military family as a whole shared the pre-deployment transition: all family members felt uncertain about the future, needed to complete tasks to "get ready" for deployment, and experienced a sense of distancing in preparation for the upcoming separation. The AD member went through the deployment transition independently, needing to "stay engaged" with the military mission, building a surrogate family and simultaneously trying to maintain connection with the family at home. In parallel, the home front family was going through a transposement transition, moving forward as an altered family unit, taking on new roles and responsibilities, and trying to simultaneously connect with the deployed member and find support from other military families. In post-deployment, the family went through the "reintegration" transition together, managing expectations, and readjusting family roles, all needing understanding and appreciation for their sacrifices during the recent separation. Effective family communication was important for military family well-being after deployment but unexpectedly challenging for many. Clinical, research, and policy recommendations are discussed. © 2015 Wiley Periodicals, Inc. This article has been contributed to by a US Government employee and her work is in the public domain in the USA.

  13. Comparing post-deployment mental health services utilization in soldiers deployed to Balkan, Iraq and Afghanistan

    DEFF Research Database (Denmark)

    Madsen, T; Sadowa Vedtofte, M; Nordentoft, M

    2017-01-01

    OBJECTIVE: Insight on how different missions have impacted rates of mental health service (MHS) utilization is unexplored. We compared postdeployment MHS utilization in a national cohort of first-time deployed to missions in Balkan, Iraq, and Afghanistan respectively. METHODS: A prospective...... national cohort study of 13 246 first-time deployed in the period 1996 through 2012 to missions in Balkan area, Iraq, or Afghanistan respectively. Soldiers 'MHS utilization was also compared with a 5:1 sex-, age-, and calendar year-matched never-deployed background population. Postdeployment utilization...... of psychotropics. RESULTS: Utilizing of psychiatric outpatient services and psychotropics was significantly higher in first-time deployed to Iraq and Afghanistan compared with deployed to Balkan. However, the rate of postdeployment admission to psychiatric hospital did not differ between missions. Postdeployment...

  14. Development of corotational formulated FEM for application to 30m class large deployable reflector

    International Nuclear Information System (INIS)

    Ozawa, Satoru; Fujiwara, Yuuichi; Tsujihata, Akio

    2010-01-01

    JAXA, Japan Aerospace Exploration Agency, is now developing a corotational formulated finite element analysis method and its software 'Origami/ETS' for the development of 30m class large deployable reflectors. For the reason that the deployable reflector is composed of beams, cables and mesh, this analysis method is generalized for finite elements with multiple nodes, which are commonly used in linear finite element analyses. The large displacement and rotation are taken into account by the corotational formulation. The tangent stiffness matrix for finite elements with multiple nodes is obtained as follows; the geometric stiffness matrix of two node elements is derived by taking variation of the element's corotational matrix from the virtual work of finite elements with large displacement; similarly the geometric stiffness matrix for three node elements is derived; as the extension of two and three node element theories, the geometric stiffness matrix for multiple node elements is derived; with the geometric stiffness matrix for multiple node elements, the tangent stiffness matrix is obtained. The analysis method is applied for the deployment analysis and static structural analysis of the 30m class large deployable reflector. In the deployment analysis, it is confirmed that this method stably analyzes the deployment motion from the deployment configuration to the stowed configuration of the reflector. In the static analysis, it is confirmed that the mesh structure is analyzed successfully. The 30m class large deployable reflector is now still being developed and is about to undergo several tests with its prototypes. This analysis method will be used in the tests and verifications of the reflector.

  15. Industrial deployment of system engineering methods

    CERN Document Server

    Romanovsky, Alexander

    2013-01-01

    A formal method is not the main engine of a development process, its contribution is to improve system dependability by motivating formalisation where useful. This book summarizes the results of the DEPLOY research project on engineering methods for dependable systems through the industrial deployment of formal methods in software development. The applications considered were in automotive, aerospace, railway, and enterprise information systems, and microprocessor design.  The project introduced a formal method, Event-B, into several industrial organisations and built on the lessons learned to

  16. Challenges to Deploy Service Design in Organizations

    DEFF Research Database (Denmark)

    Akasaka, Fumiya; Ohno, Takehiko; Jensen, Mika Yasuoka

    2016-01-01

    More and more companies are applying service design approaches to develop services and products. Not every project, however, has achieved its goals. In many cases, difficulties arise from organizational issues such as organization structure and evaluation system. In this research, we held workshops...... where success and failure factors of service design projects in organization are presented. By analysing the results, we construct a model that explains the “difficulties of deploying the service design approach in organization.” On the basis of the model, this paper discusses the challenges...... to the deployment of the service design approach in organizations....

  17. Risk and protective factors for suicidal ideation and suicide attempts among deployed Danish soldiers from 1990 to 2009.

    Science.gov (United States)

    Ejdesgaard, Bo Andersen; Zøllner, Lilian; Jensen, Børge Frank; Jørgensen, Hans-Ole; Kähler, Henrik

    2015-01-01

    The study was undertaken to identify risk and protective factors for suicidal ideation and suicide attempts among deployed Danish soldiers. Research on suicide among Danish veterans has only been conducted to a limited degree. The method applied was a questionnaire survey administered to a population of 1,264 Danish soldiers deployed from 1990 to 2009. The data were analyzed using backward logistic regression modeling in SAS 9.2. In the logistic regression analysis, the following were significant risk factors for suicidal ideation: drug abuse, a poor financial situation before deployment, a heavy workload and/or repatriation during deployment, and attending a poor athletic and recreation program after deployment. Significant protective factors against suicidal ideation were support from friends at home during deployment and appreciation by the general population after deployment. Significant risk factors for suicide attempts were an unhappy childhood and pointless tasks during deployment. No significant protective factors against suicide attempts were identified. On the basis of the results presented in this study, intervention against suicidal behavior would benefit from screening for certain childhood issues, drug abuse, and poor financial situation before deployment. During deployment, measures should be taken to minimize the amount of meaningless tasks and heavy workloads. At the same time, efficient ways of communicating with home should be ensured. After deployment, good athletic and recreation programs should be warranted for all military personnel-including repatriated soldiers. Finally, priority should be given to ensure public appreciation of what deployed soldiers accomplish. Reprint & Copyright © 2015 Association of Military Surgeons of the U.S.

  18. Analyzing petabytes of data with Hadoop

    CERN Multimedia

    CERN. Geneva

    2009-01-01

    Abstract The open source Apache Hadoop project provides a powerful suite of tools for storing and analyzing petabytes of data using commodity hardware. After several years of production use inside of web companies like Yahoo! and Facebook and nearly a year of commercial support and development by Cloudera, the technology is spreading rapidly through other disciplines, from financial services and government to life sciences and high energy physics. The talk will motivate the design of Hadoop and discuss some key implementation details in depth. It will also cover the major subprojects in the Hadoop ecosystem, go over some example applications, highlight best practices for deploying Hadoop in your environment, discuss plans for the future of the technology, and provide pointers to the many resources available for learning more. In addition to providing more information about the Hadoop platform, a major goal of this talk is to begin a dialogue with the ATLAS research team on how the tools commonly used in t...

  19. DNA Camouflage

    Science.gov (United States)

    2016-01-08

    1 DNA Camouflage Supplementary Information Bijan Zakeri1,2*, Timothy K. Lu1,2*, Peter A. Carr2,3* 1Department of Electrical Engineering and...ll.mit.edu). Distribution A: Public Release   2 Supplementary Figure 1 DNA camouflage with the 2-state device. (a) In the presence of Cre, DSD-2[α...10 1 + Cre 1 500 1,000 length (bp) chromatogram alignment template − Cre   4 Supplementary Figure 3 DNA camouflage with a switchable

  20. Deployment Strategies and Clustering Protocols Efficiency

    Directory of Open Access Journals (Sweden)

    Chérif Diallo

    2017-06-01

    Full Text Available Wireless sensor networks face significant design challenges due to limited computing and storage capacities and, most importantly, dependence on limited battery power. Energy is a critical resource and is often an important issue to the deployment of sensor applications that claim to be omnipresent in the world of future. Thus optimizing the deployment of sensors becomes a major constraint in the design and implementation of a WSN in order to ensure better network operations. In wireless networking, clustering techniques add scalability, reduce the computation complexity of routing protocols, allow data aggregation and then enhance the network performance. The well-known MaxMin clustering algorithm was previously generalized, corrected and validated. Then, in a previous work we have improved MaxMin by proposing a Single- node Cluster Reduction (SNCR mechanism which eliminates single-node clusters and then improve energy efficiency. In this paper, we show that MaxMin, because of its original pathological case, does not support the grid deployment topology, which is frequently used in WSN architectures. The unreliability feature of the wireless links could have negative impacts on Link Quality Indicator (LQI based clustering protocols. So, in the second part of this paper we show how our distributed Link Quality based d- Clustering Protocol (LQI-DCP has good performance in both stable and high unreliable link environments. Finally, performance evaluation results also show that LQI-DCP fully supports the grid deployment topology and is more energy efficient than MaxMin.

  1. Iron Status of Deployed Military Members

    Science.gov (United States)

    2017-01-04

    ready force Deploy with and care for the warrior Care for all entrusted to our care Nursing Competencies and Practice: Patient outcomes...duties, physical activities, iron intake through diet ). This additional information would improve the ability to determine factors associated with

  2. Microsoft System Center Configuration Manager advanced deployment

    CERN Document Server

    Coupland, Martyn

    2014-01-01

    If you are an experienced Configuration Manager administrator looking to advance your career or get more from your current environment, then this book is ideal for you. Prior experience of deploying and managing a Configuration Manager site would be helpful in following the examples throughout this book.

  3. Military Deployment and Elementary Student Achievement

    Science.gov (United States)

    Phelps, Terri; Dunham, Mardis; Lyons, Robert

    2010-01-01

    This study investigated the impact that military deployment has upon academic achievement of elementary school students. TerraNova test scores of 137 fourth and fifth grade students in two elementary schools with a high proportion of military dependent children were examined for two consecutive years. Although the academic test performance fell…

  4. 77 FR 36903 - Accelerating Broadband Infrastructure Deployment

    Science.gov (United States)

    2012-06-20

    ... the Nation's global competitiveness in the 21st century, driving job creation, promoting innovation, and expanding markets for American businesses. Broadband access also affords public safety agencies... infrastructure has been deployed in a vast majority of communities across the country, today too many areas still...

  5. Guam: U.S. Defense Deployments

    Science.gov (United States)

    2013-11-15

    August 8, 2013; Ta Kung Pao, August 12, 2013. 22 Sam Kim, “N. Korea Deploys Medium-Range Missiles, Bolsters Special Forces,” Yonhap, Seoul, February 23...building up its submarine force (both nuclear-powered and diesel-electric). In November 2004, the PLA Navy sent a Han -class nuclear attack submarine

  6. Very Low Head Turbine Deployment in Canada

    International Nuclear Information System (INIS)

    Kemp, P; Williams, C; Sasseville, Remi; Anderson, N

    2014-01-01

    The Very Low Head (VLH) turbine is a recent turbine technology developed in Europe for low head sites in the 1.4 - 4.2 m range. The VLH turbine is primarily targeted for installation at existing hydraulic structures to provide a low impact, low cost, yet highly efficient solution. Over 35 VLH turbines have been successfully installed in Europe and the first VLH deployment for North America is underway at Wasdell Falls in Ontario, Canada. Deployment opportunities abound in Canada with an estimated 80,000 existing structures within North America for possible low-head hydro development. There are several new considerations and challenges for the deployment of the VLH turbine technology in Canada in adapting to the hydraulic, environmental, electrical and social requirements. Several studies were completed to determine suitable approaches and design modifications to mitigate risk and confirm turbine performance. Diverse types of existing weirs and spillways pose certain hydraulic design challenges. Physical and numerical modelling of the VLH deployment alternatives provided for performance optimization. For this application, studies characterizing the influence of upstream obstacles using water tunnel model testing as well as full-scale prototype flow dynamics testing were completed. A Cold Climate Adaptation Package (CCA) was developed to allow year-round turbine operation in ice covered rivers. The CCA package facilitates turbine extraction and accommodates ice forces, frazil ice, ad-freezing and cold temperatures that are not present at the European sites. The Permanent Magnet Generator (PMG) presents some unique challenges in meeting Canadian utility interconnection requirements. Specific attention to the frequency driver control and protection requirements resulted in a driver design with greater over-voltage capability for the PMG as well as other key attributes. Environmental studies in Europe included fish friendliness testing comprised of multiple in

  7. Very Low Head Turbine Deployment in Canada

    Science.gov (United States)

    Kemp, P.; Williams, C.; Sasseville, Remi; Anderson, N.

    2014-03-01

    The Very Low Head (VLH) turbine is a recent turbine technology developed in Europe for low head sites in the 1.4 - 4.2 m range. The VLH turbine is primarily targeted for installation at existing hydraulic structures to provide a low impact, low cost, yet highly efficient solution. Over 35 VLH turbines have been successfully installed in Europe and the first VLH deployment for North America is underway at Wasdell Falls in Ontario, Canada. Deployment opportunities abound in Canada with an estimated 80,000 existing structures within North America for possible low-head hydro development. There are several new considerations and challenges for the deployment of the VLH turbine technology in Canada in adapting to the hydraulic, environmental, electrical and social requirements. Several studies were completed to determine suitable approaches and design modifications to mitigate risk and confirm turbine performance. Diverse types of existing weirs and spillways pose certain hydraulic design challenges. Physical and numerical modelling of the VLH deployment alternatives provided for performance optimization. For this application, studies characterizing the influence of upstream obstacles using water tunnel model testing as well as full-scale prototype flow dynamics testing were completed. A Cold Climate Adaptation Package (CCA) was developed to allow year-round turbine operation in ice covered rivers. The CCA package facilitates turbine extraction and accommodates ice forces, frazil ice, ad-freezing and cold temperatures that are not present at the European sites. The Permanent Magnet Generator (PMG) presents some unique challenges in meeting Canadian utility interconnection requirements. Specific attention to the frequency driver control and protection requirements resulted in a driver design with greater over-voltage capability for the PMG as well as other key attributes. Environmental studies in Europe included fish friendliness testing comprised of multiple in

  8. DNA Origami-Graphene Hybrid Nanopore for DNA Detection.

    Science.gov (United States)

    Barati Farimani, Amir; Dibaeinia, Payam; Aluru, Narayana R

    2017-01-11

    DNA origami nanostructures can be used to functionalize solid-state nanopores for single molecule studies. In this study, we characterized a nanopore in a DNA origami-graphene heterostructure for DNA detection. The DNA origami nanopore is functionalized with a specific nucleotide type at the edge of the pore. Using extensive molecular dynamics (MD) simulations, we computed and analyzed the ionic conductivity of nanopores in heterostructures carpeted with one or two layers of DNA origami on graphene. We demonstrate that a nanopore in DNA origami-graphene gives rise to distinguishable dwell times for the four DNA base types, whereas for a nanopore in bare graphene, the dwell time is almost the same for all types of bases. The specific interactions (hydrogen bonds) between DNA origami and the translocating DNA strand yield different residence times and ionic currents. We also conclude that the speed of DNA translocation decreases due to the friction between the dangling bases at the pore mouth and the sequencing DNA strands.

  9. Abstracting application deployment on Cloud infrastructures

    Science.gov (United States)

    Aiftimiei, D. C.; Fattibene, E.; Gargana, R.; Panella, M.; Salomoni, D.

    2017-10-01

    Deploying a complex application on a Cloud-based infrastructure can be a challenging task. In this contribution we present an approach for Cloud-based deployment of applications and its present or future implementation in the framework of several projects, such as “!CHAOS: a cloud of controls” [1], a project funded by MIUR (Italian Ministry of Research and Education) to create a Cloud-based deployment of a control system and data acquisition framework, “INDIGO-DataCloud” [2], an EC H2020 project targeting among other things high-level deployment of applications on hybrid Clouds, and “Open City Platform”[3], an Italian project aiming to provide open Cloud solutions for Italian Public Administrations. We considered to use an orchestration service to hide the complex deployment of the application components, and to build an abstraction layer on top of the orchestration one. Through Heat [4] orchestration service, we prototyped a dynamic, on-demand, scalable platform of software components, based on OpenStack infrastructures. On top of the orchestration service we developed a prototype of a web interface exploiting the Heat APIs. The user can start an instance of the application without having knowledge about the underlying Cloud infrastructure and services. Moreover, the platform instance can be customized by choosing parameters related to the application such as the size of a File System or the number of instances of a NoSQL DB cluster. As soon as the desired platform is running, the web interface offers the possibility to scale some infrastructure components. In this contribution we describe the solution design and implementation, based on the application requirements, the details of the development of both the Heat templates and of the web interface, together with possible exploitation strategies of this work in Cloud data centers.

  10. Fiscal 1999 project for research and development of industrial and scientific technologies. Report on the achievements on the 'research and development of an ultimate atom and molecule manipulation technology' (Development of a technology to analyze and manipulate DNAs at high efficiency); 1999 nendo genshi bunshi kyokugen sosa gijutsu no kenkyu kaihatsu seika hokokusho. DNA nado kokoritsu kaiseki sosa gijutsu kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    In the 'research and development of an ultimate atom and molecule manipulation technology', research has been made on an organic atom and molecule identification and manipulation technology and a dynamic organic molecule simulation technology. This paper summarizes the achievements in fiscal 1999. In the magnetic force controlling AFM for the force spectroscopy aimed at non-destructive atom and molecule identification, a prototype cantilever was fabricated that can excite and detect displacement in lateral direction and is suitable for friction measurement. The SrO surface and TiO2 surface of SrTiO{sub 3}. A carbon nano-tube was employed as a probe. In addition, the molecule inserting SAM technology was used to have developed a technology to measure electric conductivity inside and between molecules. With an aim at realizing a high-speed DNA base arrangement analyzing method, research is being performed upon noticing the single molecule method based on the light measuring method using the single molecule imaging as the base and the scanning probe microscope method. For the dynamic organic molecule simulation technology, theoretical analysis was advanced on synthesis of methanol on copper surface. (NEDO)

  11. An efficient genetic algorithm for maximum coverage deployment in wireless sensor networks.

    Science.gov (United States)

    Yoon, Yourim; Kim, Yong-Hyuk

    2013-10-01

    Sensor networks have a lot of applications such as battlefield surveillance, environmental monitoring, and industrial diagnostics. Coverage is one of the most important performance metrics for sensor networks since it reflects how well a sensor field is monitored. In this paper, we introduce the maximum coverage deployment problem in wireless sensor networks and analyze the properties of the problem and its solution space. Random deployment is the simplest way to deploy sensor nodes but may cause unbalanced deployment and therefore, we need a more intelligent way for sensor deployment. We found that the phenotype space of the problem is a quotient space of the genotype space in a mathematical view. Based on this property, we propose an efficient genetic algorithm using a novel normalization method. A Monte Carlo method is adopted to design an efficient evaluation function, and its computation time is decreased without loss of solution quality using a method that starts from a small number of random samples and gradually increases the number for subsequent generations. The proposed genetic algorithms could be further improved by combining with a well-designed local search. The performance of the proposed genetic algorithm is shown by a comparative experimental study. When compared with random deployment and existing methods, our genetic algorithm was not only about twice faster, but also showed significant performance improvement in quality.

  12. A Raman-Based Portable Fuel Analyzer

    Science.gov (United States)

    Farquharson, Stuart

    2010-08-01

    Fuel is the single most import supply during war. Consider that the US Military is employing over 25,000 vehicles in Iraq and Afghanistan. Most fuel is obtained locally, and must be characterized to ensure proper operation of these vehicles. Fuel properties are currently determined using a deployed chemical laboratory. Unfortunately, each sample requires in excess of 6 hours to characterize. To overcome this limitation, we have developed a portable fuel analyzer capable of determine 7 fuel properties that allow determining fuel usage. The analyzer uses Raman spectroscopy to measure the fuel samples without preparation in 2 minutes. The challenge, however, is that as distilled fractions of crude oil, all fuels are composed of hundreds of hydrocarbon components that boil at similar temperatures, and performance properties can not be simply correlated to a single component, and certainly not to specific Raman peaks. To meet this challenge, we measured over 800 diesel and jet fuels from around the world and used chemometrics to correlate the Raman spectra to fuel properties. Critical to the success of this approach is laser excitation at 1064 nm to avoid fluorescence interference (many fuels fluoresce) and a rugged interferometer that provides 0.1 cm-1 wavenumber (x-axis) accuracy to guarantee accurate correlations. Here we describe the portable fuel analyzer, the chemometric models, and the successful determination of these 7 fuel properties for over 100 unknown samples provided by the US Marine Corps, US Navy, and US Army.

  13. [Single-molecule detection and characterization of DNA replication based on DNA origami].

    Science.gov (United States)

    Wang, Qi; Fan, Youjie; Li, Bin

    2014-08-01

    To investigate single-molecule detection and characterization of DNA replication. Single-stranded DNA (ssDNA) as the template of DNA replication was attached to DNA origami by a hybridization reaction based on the complementary base-pairing principle. DNA replication catalyzed by E.coli DNA polymerase I Klenow Fragment (KF) was detected using atomic force microscopy (AFM). The height variations between the ssDNA and the double-stranded DNA (dsDNA), the distribution of KF during DNA replication and biotin-streptavidin (BA) complexes on the DNA strand after replication were detected. Agarose gel electrophoresis was employed to analyze the changes in the DNA after replication. The designed ssDNA could be anchored on the target positions of over 50% of the DNA origami. The KF was capable of binding to the ssDNA fixed on DNA origami and performing its catalytic activities, and was finally dissociated from the DNA after replication. The height of DNA strand increased by about 0.7 nm after replication. The addition of streptavidin also resulted in an DNA height increase to about 4.9 nm due to the formation of BA complexes on the biotinylated dsDNA. The resulting dsDNA and BA complex were subsequently confirmed by agarose gel electrophoresis. The combination of AFM and DNA origami allows detection and characterization of DNA replication at the single molecule level, and this approach provides better insights into the mechanism of DNA polymerase and the factors affecting DNA replication.

  14. DNA glue

    DEFF Research Database (Denmark)

    Filichev, Vyacheslav V; Astakhova, Irina V.; Malakhov, Andrei D.

    2008-01-01

    Significant alterations in thermal stability of parallel DNA triplexes and antiparallel duplexes were observed upon changing the attachment of ethynylpyrenes from para to ortho in the structure of phenylmethylglycerol inserted as a bulge into DNA (TINA). Insertions of two ortho-TINAs as a pseudo...

  15. Hyperstretching DNA

    NARCIS (Netherlands)

    Schakenraad, Koen; Biebricher, Andreas S.; Sebregts, Maarten; Ten Bensel, Brian; Peterman, Erwin J.G.; Wuite, Gijs J L; Heller, Iddo; Storm, Cornelis; Van Der Schoot, Paul

    2017-01-01

    The three-dimensional structure of DNA is highly susceptible to changes by mechanical and biochemical cues in vivo and in vitro. In particular, large increases in base pair spacing compared to regular B-DNA are effected by mechanical (over)stretching and by intercalation of compounds that are widely

  16. Garden State Parkway Corridor : ITS early deployment planning study : strategic deployment plan

    Science.gov (United States)

    1997-12-01

    This Strategic Deployment Plan describes ways of improving travel within the Garden : State Parkway Corridor using intelligent transportation systems (ITS) and without : constructing additional roadway lanes. Travel improvements will be possible with...

  17. Food and drinking water hygiene and intestinal protozoa in deployed German soldiers.

    Science.gov (United States)

    Frickmann, Hagen; Schwarz, Norbert G; Wiemer, Dorothea F; Fischer, Marcellus; Tannich, Egbert; Scheid, Patrick L; Müller, Martin; Schotte, Ulrich; Bock, Wolfgang; Hagen, Ralf M

    2013-03-01

    This report analyzes the occurrence of Cryptosporidium spp., E. histolytica, and G. intestinalis in stool of returnees from military deployments and the impact of hygiene precautions. Between 2007 and 2010, stool samples of 830 returnees that were obtained 8-12 weeks after military deployments in Afghanistan, Uzbekistan, the Balkans, Democratic Republic of the Congo/Gabonese Republic, and Sudan and 292 control samples from non-deployed soldiers were analyzed by PCR for Cryptosporidium spp., E. histolytica, G. intestinalis, and the commensal indicator of fecal contamination E. dispar. Data on hygiene precautions were available. The soldiers were questioned regarding gastrointestinal and general symptoms. Among 1122 stool samples, 18 were positive for G. intestinalis, 10 for E. dispar, and no-one for Cryptosporidium spp. and E. histolytica. An increased risk of acquiring chronic parasitic infections in comparison with non-deployed controls was demonstrated only for G. intestinalis in Sudan, where standardized food and drinking water hygiene precautions could not be implemented. Standard food and drinking water hygiene precautions in the context of screened military field camps proved to be highly reliable in preventing food-borne and water-borne chronic infections and colonization by intestinal protozoa, leading to detection proportions similar to those in non-deployed controls.

  18. Deployable reflector configurations. [for space telescope

    Science.gov (United States)

    Meinel, A. B.; Meinel, M. P.; Woolf, N. J.

    1983-01-01

    Both the theoretical reasons for considering a non-circular format for the Large Deployable Reflector, and a potentially realizable concept for such a device, are discussed. The optimum systems for diffraction limited telescopes with incoherent detection have either a single filled aperture, or two such apertures as an interferometer to synthesize a larger aperture. For a single aperture of limited area, a reflector in the form of a slot can be used to give increased angular resolution. It is shown how a 20 x 8 meter telescope can be configured to fit the Space Shuttle bay, and deployed with relatively simple operations. The relationship between the sunshield design and the inclination of the orbit is discussed. The possible use of the LDR as a basic module to permit the construction of supergiant space telescopes and interferometers both for IR/submm studies and for the entire ultraviolet through mm wave spectral region is discussed.

  19. Planning and Management of Technology Deployment Center

    International Nuclear Information System (INIS)

    Park, Jae Won; Joo, Po Kook; Kim, Jun Yeon and others

    2005-08-01

    The R and D contents are summarized as follows ; Models were set-up for transferring the developed technologies to the industry and managing technology deployment center to vitalize the commercialization and then the set-up model was tried to apply for transferring technologies for commercialization and to define interfaces between the R and D and industrial applications In this project, new products and processes were developed for promoting the commercialization. Infra-structures were firmly set-up for the venture company promotion and technology deployment developed during executing the proton Engineering frontier Project. Commercialization methodology connection with industrial companies were studied by outside specializing institute. Development of gem-stone coloring and new photo catalyst producing techniques are very high value-adding technologies, therefore, experimental and theoretical R and D were transacted simultaneously to obtain the originality of the technology. The theoretical R and D was committed to a specialist outside

  20. Analyze of the Measuring Performance for Artificially Business Intelligent Systems

    OpenAIRE

    Vatuiu, Teodora

    2007-01-01

    This paper analyzes the measuring performance of artificially business intelligent systems. Thousands of persons-years have been devoted to the research and development in the vari¬ous aspects of artificially intelligent systems. Much progress has been attained. However, there has been no means of evaluating the progress of the field. How can we assess the cur¬rent state of the science? Most of business intelligent systems are beginning to be deployed commercially. How can a commercial buyer ...

  1. Towards the Ubiquitous Deployment of DNSSEC

    Science.gov (United States)

    2016-01-01

    and Session Initiation Protocol ( SIP ). However, it remains to be seen how quickly these enhancements are picked up and deployed. The second...Security RDI Resources for the DNSSEC Initiative System (the C&A system) RFC Request For Comments SIP Session Initiation Protocol SMTP Simple Mail...DISTRIBUTION UNLIMITED 1 Summary The Secure Extensions to the Domain Name System (DNSSEC) comprise of a set of protocol extensions that fix a

  2. THE PROTECTION AND DEPLOYMENT OF FINANCIAL INNOVATION

    OpenAIRE

    PETER GIANIODIS; JILL A. BROWN

    2013-01-01

    Prevailing theory suggests that firms that effectively protect technological discoveries from emulation will create and capture value. Despite its importance, little research has examined the specific mechanisms of how to protect technological discoveries, and have heretofore emphasized the importance of inherent resource attributes to limit competitor emulation. Using a sample of financial patents, we test theory regarding the effects of resource attributes and deployment mechanisms on resou...

  3. IRIS. Progress in licensing and toward deployment

    International Nuclear Information System (INIS)

    Petrovic, B.; Carelli, M.D.; Kling, C.L.; Cavlina, N.; Grgic, D.

    2006-01-01

    The International Reactor Innovative and Secure (IRIS) is an advanced, integral, light water cooled, pressurized reactor of smaller generating capacity (1000 MWt, or 335 MWe). It is being developed through a strong international partnership by a team lead by Westinghouse and including organizations from 10 countries. The main objective of the project is to offer a simple nuclear power plant with outstanding safety, attractive economics and enhanced proliferation resistance characteristics ready for deployment within the next decade. IRIS embodies the requirements set forth by the recently announced US DOE Global Nuclear Energy Partnership (GNEP) program for worldwide deployment of a smaller-scale reactors and provides a viable bridge to Generation IV reactors. IRIS is designed to address the needs of both developed and emerging markets. Its smaller power level provides deployment flexibility in larger developed markets, and makes it in particular well suited for markets with limited grids or where the annual energy demand growth is moderate. Due to its short construction time and the staggered build option, IRIS significantly reduces the required financing, improves cash flow, and provides a viable solution for economies with limited resources. While based on proven and worldwide accepted LWR technology, IRIS introduces a number of innovative solutions to simplify its design and improve safety and operational characteristics, including the integral primary system and its components, as well as the safety-by-design approach. These features will be tested and demonstrated in a testing program that has been initiated. As its centerpiece, the program will include the integral test facility. Results of this program will support licensing with the US NRC. A multinational licensing is considered to facilitate worldwide deployment. (author)

  4. Bomber Deployments: A New Power Projection Strategy

    Science.gov (United States)

    2016-08-21

    AIR COMMAND AND STAFF COLLEGE DISTANCE LEARNING AIR UNIVERSITY BOMBER DEPLOYMENTS: A NEW POWER PROJECTION STRATEGY by...operating base (FOB), main operating base ( MOB ) and intermediate staging base (ISB).10 Each type of base requires certain actions to make it suitable for...closure of many main operating bases ( MOB ) overseas and the reluctance of many nations to permit permanent military bases on their soil.”15 This

  5. Quality Function Deployment for Large Systems

    Science.gov (United States)

    Dean, Edwin B.

    1992-01-01

    Quality Function Deployment (QFD) is typically applied to small subsystems. This paper describes efforts to extend QFD to large scale systems. It links QFD to the system engineering process, the concurrent engineering process, the robust design process, and the costing process. The effect is to generate a tightly linked project management process of high dimensionality which flushes out issues early to provide a high quality, low cost, and, hence, competitive product. A pre-QFD matrix linking customers to customer desires is described.

  6. DNA probes

    International Nuclear Information System (INIS)

    Castelino, J.

    1992-01-01

    The creation of DNA probes for detection of specific nucleotide segments differs from ligand detection in that it is a chemical rather than an immunological reaction. Complementary DNA or RNA is used in place of the antibody and is labelled with 32 P. So far, DNA probes have been successfully employed in the diagnosis of inherited disorders, infectious diseases, and for identification of human oncogenes. The latest approach to the diagnosis of communicable and parasitic infections is based on the use of deoxyribonucleic acid (DNA) probes. The genetic information of all cells is encoded by DNA and DNA probe approach to identification of pathogens is unique because the focus of the method is the nucleic acid content of the organism rather than the products that the nucleic acid encodes. Since every properly classified species has some unique nucleotide sequences that distinguish it from every other species, each organism's genetic composition is in essence a finger print that can be used for its identification. In addition to this specificity, DNA probes offer other advantages in that pathogens may be identified directly in clinical specimens

  7. DNA probes

    Energy Technology Data Exchange (ETDEWEB)

    Castelino, J

    1993-12-31

    The creation of DNA probes for detection of specific nucleotide segments differs from ligand detection in that it is a chemical rather than an immunological reaction. Complementary DNA or RNA is used in place of the antibody and is labelled with {sup 32}P. So far, DNA probes have been successfully employed in the diagnosis of inherited disorders, infectious diseases, and for identification of human oncogenes. The latest approach to the diagnosis of communicable and parasitic infections is based on the use of deoxyribonucleic acid (DNA) probes. The genetic information of all cells is encoded by DNA and DNA probe approach to identification of pathogens is unique because the focus of the method is the nucleic acid content of the organism rather than the products that the nucleic acid encodes. Since every properly classified species has some unique nucleotide sequences that distinguish it from every other species, each organism`s genetic composition is in essence a finger print that can be used for its identification. In addition to this specificity, DNA probes offer other advantages in that pathogens may be identified directly in clinical specimens 10 figs, 2 tabs

  8. Reactor power system deployment and startup

    International Nuclear Information System (INIS)

    Wetch, J.R.; Nelin, C.J.; Britt, E.J.; Klein, G.; Rasor Associates, Inc., Sunnyvale, CA; California Institute of Technology, Pasadena)

    1985-01-01

    This paper addresses issues that should receive further examination in the near-term as concept selection for development of a U.S. space reactor power system is approached. The issues include: the economics, practicality and system reliability associated with transfer of nuclear spacecraft from low earth shuttle orbits to operational orbits, via chemical propulsion versus nuclear electric propulsion; possible astronaut supervised reactor and nuclear electric propulsion startup in low altitude Shuttle orbit; potential deployment methods for nuclear powered spacecraft from Shuttle; the general public safety of low altitude startup and nuclear safe and disposal orbits; the question of preferred reactor power level; and the question of frozen versus molten alkali metal coolant during launch and deployment. These issues must be considered now because they impact the SP-100 concept selection, power level selection, weight and size limits, use of deployable radiators, reliability requirements, and economics, as well as the degree of need for and the urgency of developing space reactor power systems. 5 references

  9. Remotely deployable aerial inspection using tactile sensors

    Science.gov (United States)

    MacLeod, C. N.; Cao, J.; Pierce, S. G.; Sullivan, J. C.; Pipe, A. G.; Dobie, G.; Summan, R.

    2014-02-01

    For structural monitoring applications, the use of remotely deployable Non-Destructive Evaluation (NDE) inspection platforms offer many advantages, including improved accessibility, greater safety and reduced cost, when compared to traditional manual inspection techniques. The use of such platforms, previously reported by researchers at the University Strathclyde facilitates the potential for rapid scanning of large areas and volumes in hazardous locations. A common problem for both manual and remote deployment approaches lies in the intrinsic stand-off and surface coupling issues of typical NDE probes. The associated complications of these requirements are obviously significantly exacerbated when considering aerial based remote inspection and deployment, resulting in simple visual techniques being the preferred sensor payload. Researchers at Bristol Robotics Laboratory have developed biomimetic tactile sensors modelled on the facial whiskers (vibrissae) of animals such as rats and mice, with the latest sensors actively sweeping their tips across the surface in a back and forth motion. The current work reports on the design and performance of an aerial inspection platform and the suitability of tactile whisking sensors to aerial based surface monitoring applications.

  10. FBR/VHTR deployment scenarios in Japan

    International Nuclear Information System (INIS)

    Richards, Matt; Kunitomi, Kazuhiko

    2008-01-01

    Co-deployment of Fast Breeder Reactors (FBRs) and Very High Temperature Reactors (VHTRs) can be used as the nuclear technologies to meet a significant portion of Japan's future energy demands. The FBR provides the fissile fuel for energy security and sustainability, and can be used to provide a significant portion of the electricity demand. The VHTR can provide flexible energy outputs (electricity, hydrogen, and high-temperature heat) with high efficiency, can operate with a wide variety of fuel cycles, and can be sited at locations that have limited availability of cooling water. These features, combined with its passive safety and high degree of proliferation resistance, make the VHTR an ideal complement for co-deployment with the FBR in Japan and also a very low-risk technology of export to foreign countries. In addition to hydrogen production, the high-temperature thermal energy produced by the VHTR fleet can be used for a wide variety of process-heat applications, and the VHTR can play a key role for significantly reducing greenhouse-gas emissions. This paper describes assessments for deploying FBRs and VHTRs in Japan using a closed fuel cycle, with the FBRs supplying the fissile material to sustain the combined FBR/VHTR fleet. (author)

  11. Hybrid deployable support truss designs for LDR

    Science.gov (United States)

    Hedgepeth, J.

    1988-01-01

    Concepts for a 20-meter diameter Large Deployable Reflector (LDR) deployable truss backup structure, and analytical predictions of its structural characteristics are discussed. The concept shown is referred to as the SIXPAC; It is a combination of the PACTRUSS concept and a single-fold beam, which would make up the desired backup structure. One advantage of retaining the PACTRUSS concept is its packaging density and its capability for synchronous deployment. Various 2-meter hexagonal panel arrangements are possible for this Hybrid PACTRUSS structure depending on the panel-to-structure attachment strategies used. Static analyses of the SIXPAC using various assumptions for truss designs and panel masses of 10 kg sq meters were performed to predict the tip displacement of the structure when supported at the center. The tip displacement ranged from 0.20 to 0.44 mm without the panel mass, and from 0.9 to 3.9 mm with the panel mass (in a 1-g field). The data indicate that the structure can be adequately ground tested to validate its required performance in space, assuming the required performance in space is approximately 100 microns. The static displacement at the tip of the structure when subjected to an angular acceleration of 0.001 rad/sec squared were estimated to range from 0.8 to 7.5 microns, depending on the type of truss elements.

  12. Multichannel analyzer development in CAMAC

    International Nuclear Information System (INIS)

    Nagy, J.Z.; Zarandy, A.

    1988-01-01

    The data acquisition in TOKAMAK experiments some CAMAC modules have been developed. The modules are the following: 64 K analyzer memory, 32 K analyzer memory, 6-channel pulse peak analyzer memory which contains the 32 K analyzer memory and eight AD-converters

  13. Space Surveillance Catalog growth during SBIRS low deployment.

    Science.gov (United States)

    Hoult, C. P.; Wright, R. P.

    The Space Surveillance Catalog is a database of all Resident Space Objects (RSOs) on Earth orbit. It is expected to grow in the future as more RSOs accumulate on orbit. Potentially still more dramatic growth could follow the deployment of the Space Based Infrared System Low Earth Orbit Component (SBTRS Low). SBIRS Low, currently about to enter development, offers the potential to detect and acquire much smaller debris RSOs than can be seen by the current ground-based Space Surveillance Network (SSN). SBIRS Low will host multicolor infrared/visible sensors on each satellite in a proliferated constellation on low Earth orbit, and if appropriately tasked, these sensors could provide significant space surveillance capability. Catalog growth during SBIRS Low deployment was analyzed using a highly aggregated code that numerically integrates the Markov equations governing the state transitions of RSOs from uncataloged to cataloged, and back again. It was assumed that all newly observed debris RSOs will be detected as by-products of routine Catalog maintenance, not including any post breakup searches, and if sufficient sensor resources are available, be acquired into the Catalog. Debris over the entire low to high altitude regime were considered.

  14. Modular VO oriented Java EE service deployer

    Science.gov (United States)

    Molinaro, Marco; Cepparo, Francesco; De Marco, Marco; Knapic, Cristina; Apollo, Pietro; Smareglia, Riccardo

    2014-07-01

    The International Virtual Observatory Alliance (IVOA) has produced many standards and recommendations whose aim is to generate an architecture that starts from astrophysical resources, in a general sense, and ends up in deployed consumable services (that are themselves astrophysical resources). Focusing on the Data Access Layer (DAL) system architecture, that these standards define, in the last years a web based application has been developed and maintained at INAF-OATs IA2 (Italian National institute for Astrophysics - Astronomical Observatory of Trieste, Italian center of Astronomical Archives) to try to deploy and manage multiple VO (Virtual Observatory) services in a uniform way: VO-Dance. However a set of criticalities have arisen since when the VO-Dance idea has been produced, plus some major changes underwent and are undergoing at the IVOA DAL layer (and related standards): this urged IA2 to identify a new solution for its own service layer. Keeping on the basic ideas from VO-Dance (simple service configuration, service instantiation at call time and modularity) while switching to different software technologies (e.g. dismissing Java Reflection in favour of Enterprise Java Bean, EJB, based solution), the new solution has been sketched out and tested for feasibility. Here we present the results originating from this test study. The main constraints for this new project come from various fields. A better homogenized solution rising from IVOA DAL standards: for example the new DALI (Data Access Layer Interface) specification that acts as a common interface system for previous and oncoming access protocols. The need for a modular system where each component is based upon a single VO specification allowing services to rely on common capabilities instead of homogenizing them inside service components directly. The search for a scalable system that takes advantage from distributed systems. The constraints find answer in the adopted solutions hereafter sketched. The

  15. Deployment Effects of Marin Renewable Energy Technologies

    Energy Technology Data Exchange (ETDEWEB)

    Brian Polagye; Mirko Previsic

    2010-06-17

    Given proper care in siting, design, deployment, operation and maintenance, marine and hydrokinetic technologies could become one of the more environmentally benign sources of electricity generation. In order to accelerate the adoption of these emerging hydrokinetic and marine energy technologies, navigational and environmental concerns must be identified and addressed. All developing hydrokinetic projects involve a wide variety of stakeholders. One of the key issues that site developers face as they engage with this range of stakeholders is that many of the possible conflicts (e.g., shipping and fishing) and environmental issues are not well-understood, due to a lack of technical certainty. In September 2008, re vision consulting, LLC was selected by the Department of Energy (DoE) to apply a scenario-based approach to the emerging wave and tidal technology sectors in order to evaluate the impact of these technologies on the marine environment and potentially conflicting uses. The project’s scope of work includes the establishment of baseline scenarios for wave and tidal power conversion at potential future deployment sites. The scenarios will capture variations in technical approaches and deployment scales to properly identify and characterize environmental impacts and navigational effects. The goal of the project is to provide all stakeholders with an improved understanding of the potential effects of these emerging technologies and focus all stakeholders onto the critical issues that need to be addressed. This groundwork will also help in streamlining siting and associated permitting processes, which are considered key hurdles for the industry’s development in the U.S. today. Re vision is coordinating its efforts with two other project teams funded by DoE which are focused on regulatory and navigational issues. The results of this study are structured into three reports: 1. Wave power scenario description 2. Tidal power scenario description 3. Framework for

  16. Fundamentals of 3D Deployable Mechanisms in Space

    Data.gov (United States)

    National Aeronautics and Space Administration — Fundamentals of 3D Deployable Origami Structures in Space The primary objectives of my research are to study the application of 3D deployable origami structures in...

  17. STEP flight experiments Large Deployable Reflector (LDR) telescope

    Science.gov (United States)

    Runge, F. C.

    1984-01-01

    Flight testing plans for a large deployable infrared reflector telescope to be tested on a space platform are discussed. Subsystem parts, subassemblies, and whole assemblies are discussed. Assurance of operational deployability, rigidization, alignment, and serviceability will be sought.

  18. Elastic Deployable Composite Tubular Roll-Out Boom, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — Deployable Space Systems (DSS) has developed an affordable and ultra-lightweight elastically self-deployable Roll-Out Boom technology that provides affordability and...

  19. Deployment of a multi-link flexible structure

    Science.gov (United States)

    Na, Kyung-Su; Kim, Ji-Hwan

    2006-06-01

    Deployment of a multi-link beam structure undergoing locking is analyzed in the Timoshenko beam theory. In the modeling of the system, dynamic forces are assumed to be torques and restoring forces due to the torsion spring at each joint. Hamilton's principle is used to determine the equations of motion and the finite element method is adopted to analyze the system. Newmark time integration and Newton-Raphson iteration methods are used to solve for the non-linear equations of motion at each time step. The locking at the joints of the multi-link flexible structure is analyzed by the momentum balance method. Numerical results are compared with the previous experimental data. The angles and angular velocities of each joint, tip displacement, and velocity of each link are investigated to study the motions of the links at each time step. To analyze the effect of thickness on the motion of the link, the angle and the tip displacement of each link are compared according to the various slenderness ratios. Additionally, in order to investigate the effect of shear, the tip displacements of a Timoshenko beam are compared with those of an Euler-Bernoulli beam.

  20. DNA based radiological dosimetry technology

    International Nuclear Information System (INIS)

    Diaz Quijada, Gerardo A.; Roy, Emmanuel; Veres, Teodor; Dumoulin, Michel M.; Vachon, Caroline; Blagoeva, Rosita; Pierre, Martin

    2008-01-01

    Full text: The purpose of this project is to develop a personal and wearable dosimeter using a highly-innovative approach based on the specific recognition of DNA damage with a polymer hybrid. Our biosensor will be sensitive to breaks in nucleic acid macromolecules and relevant to mixed-field radiation. The dosimeter proposed will be small, field deployable and will sense damages for all radiation types at the DNA level. The generalized concept for the novel-based radiological dosimeter: 1) Single or double stranded oligonucleotide is immobilized on surface; 2) Single stranded has higher cross-section for fragmentation; 3) Double stranded is more biological relevant; 4) Radiation induces fragmentation; 5) Ultra-sensitive detection of fragments provides radiation dose. Successful efforts have been made towards a proof-of-concept personal wearable DNA-based dosimeter that is appropriate for mixed-field radiation. The covalent immobilization of oligonucleotides on large areas of plastic surfaces has been demonstrated and corroborated spectroscopically. The surface concentration of DNA was determined to be 8 x 1010 molecules/cm 2 from a Ce(IV) catalyzed hydrolysis study of a fluorescently labelled oligonucleotide. Current efforts are being directed at studying radiation induced fragmentation of DNA followed by its ultra-sensitive detection via a novel method. In addition, proof-of-concept wearable personal devices and a detection platform are presently being fabricated. (author)

  1. DNA methylation

    DEFF Research Database (Denmark)

    Williams, Kristine; Christensen, Jesper; Helin, Kristian

    2012-01-01

    DNA methylation is involved in key cellular processes, including X-chromosome inactivation, imprinting and transcriptional silencing of specific genes and repetitive elements. DNA methylation patterns are frequently perturbed in human diseases such as imprinting disorders and cancer. The recent...... discovery that the three members of the TET protein family can convert 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) has provided a potential mechanism leading to DNA demethylation. Moreover, the demonstration that TET2 is frequently mutated in haematopoietic tumours suggests that the TET...... proteins are important regulators of cellular identity. Here, we review the current knowledge regarding the function of the TET proteins, and discuss various mechanisms by which they contribute to transcriptional control. We propose that the TET proteins have an important role in regulating DNA methylation...

  2. DNA data

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Raw DNA chromatogram data produced by the ABI 373, 377, 3130 and 3730 automated sequencing machines in ABI format. These are from fish (primarily Sebastes spp.,...

  3. DNA nanotechnology

    Science.gov (United States)

    Seeman, Nadrian C.; Sleiman, Hanadi F.

    2018-01-01

    DNA is the molecule that stores and transmits genetic information in biological systems. The field of DNA nanotechnology takes this molecule out of its biological context and uses its information to assemble structural motifs and then to connect them together. This field has had a remarkable impact on nanoscience and nanotechnology, and has been revolutionary in our ability to control molecular self-assembly. In this Review, we summarize the approaches used to assemble DNA nanostructures and examine their emerging applications in areas such as biophysics, diagnostics, nanoparticle and protein assembly, biomolecule structure determination, drug delivery and synthetic biology. The introduction of orthogonal interactions into DNA nanostructures is discussed, and finally, a perspective on the future directions of this field is presented.

  4. The deployment of routing protocols in distributed control plane of SDN.

    Science.gov (United States)

    Jingjing, Zhou; Di, Cheng; Weiming, Wang; Rong, Jin; Xiaochun, Wu

    2014-01-01

    Software defined network (SDN) provides a programmable network through decoupling the data plane, control plane, and application plane from the original closed system, thus revolutionizing the existing network architecture to improve the performance and scalability. In this paper, we learned about the distributed characteristics of Kandoo architecture and, meanwhile, improved and optimized Kandoo's two levels of controllers based on ideological inspiration of RCP (routing control platform). Finally, we analyzed the deployment strategies of BGP and OSPF protocol in a distributed control plane of SDN. The simulation results show that our deployment strategies are superior to the traditional routing strategies.

  5. The Deployment of Routing Protocols in Distributed Control Plane of SDN

    Directory of Open Access Journals (Sweden)

    Zhou Jingjing

    2014-01-01

    Full Text Available Software defined network (SDN provides a programmable network through decoupling the data plane, control plane, and application plane from the original closed system, thus revolutionizing the existing network architecture to improve the performance and scalability. In this paper, we learned about the distributed characteristics of Kandoo architecture and, meanwhile, improved and optimized Kandoo’s two levels of controllers based on ideological inspiration of RCP (routing control platform. Finally, we analyzed the deployment strategies of BGP and OSPF protocol in a distributed control plane of SDN. The simulation results show that our deployment strategies are superior to the traditional routing strategies.

  6. Psychiatric Effects of Military Deployment on Children and Families

    Science.gov (United States)

    James, Trenton

    2012-01-01

    Deployments in the United States military have increased greatly in the past 10 years. Families and children are psychiatrically affected by these deployments, and recent studies are clarifying these effects. This article focuses on the psychiatric effects of deployment on children and uses a composite case example to review the use of play therapy to treat children who are having psychiatric issues related to the deployment of one or both parents. PMID:22468239

  7. Deployment-related risk factors of low back pain

    DEFF Research Database (Denmark)

    Nissen, Lars Ravnborg; Marott, Jacob Louis; Gyntelberg, Finn

    2014-01-01

    Where much is known about the consequences of spinal and low back pain (LBP) during military deployments, there is lesser knowledge of risk factors for LBP among the deployed forces. The objective of this study was to identify deployment-related exposures associated with LBP. The study was a ques...... their subordinates and involve medical personnel, especially deployed physiotherapists, by giving advice to soldiers of different military occupational specialties on how to optimize ergonomics at work....

  8. Design aspects of a deployable tensegrity-hollow-rope footbridge

    OpenAIRE

    Rhode-Barbarigos , Landolf; Bel Hadj Ali , Nizar; Motro , René; Smith , Ian F.C.

    2012-01-01

    International audience; Tensegrity structures are composed of cables and struts in a pre-stressed self-equilibrium. Although tensegrity first appeared in the 1950s, it is seldom used in civil engineering. This paper focuses on the design aspects of a deployable tensegrity-hollow-rope footbridge. Deployment is usually not a critical design case for traditional deployable structures. However, for tensegrity systems deployment may be critical due to the actuation required. In this paper, deploym...

  9. DNA expressions - A formal notation for DNA

    NARCIS (Netherlands)

    Vliet, Rudy van

    2015-01-01

    We describe a formal notation for DNA molecules that may contain nicks and gaps. The resulting DNA expressions denote formal DNA molecules. Different DNA expressions may denote the same molecule. Such DNA expressions are called equivalent. We examine which DNA expressions are minimal, which

  10. EDITORIAL Wireless sensor networks: design for real-life deployment and deployment experiences Wireless sensor networks: design for real-life deployment and deployment experiences

    Science.gov (United States)

    Gaura, Elena; Roedig, Utz; Brusey, James

    2010-12-01

    Wireless sensor networks (WSNs) are among the most promising technologies of the new millennium. The opportunities afforded by being able to program networks of small, lightweight, low-power, computation- and bandwidth-limited nodes have attracted a large community of researchers and developers. However, the unique set of capabilities offered by the technology produces an exciting but complex design space, which is often difficult to negotiate in an application context. Deploying sensing physical environments produces its own set of challenges, and can push systems into failure modes, thus revealing problems that can be difficult to discover or reproduce in simulation or the laboratory. Sustained efforts in the area of wireless networked sensing over the last 15 years have resulted in a large number of theoretical developments, substantial practical achievements, and a wealth of lessons for the future. It is clear that in order to bridge the gap between (on the one hand) visions of very large scale, autonomous, randomly deployed networks and (on the other) the actual performance of fielded systems, we need to view deployment as an essential component in the process of developing sensor networks: a process that includes hardware and software solutions that serve specific applications and end-user needs. Incorporating deployment into the design process reveals a new and different set of requirements and considerations, whose solutions require innovative thinking, multidisciplinary teams and strong involvement from end-user communities. This special feature uncovers and documents some of the hurdles encountered and solutions offered by experimental scientists when deploying and evaluating wireless sensor networks in situ, in a variety of well specified application scenarios. The papers specifically address issues of generic importance for WSN system designers: (i) data quality, (ii) communications availability and quality, (iii) alternative, low-energy sensing

  11. Conceptual Design of Deployment Structure of Morphing Nose Cone

    Directory of Open Access Journals (Sweden)

    Junlan Li

    2013-01-01

    Full Text Available For a reusable space vehicle or a missile, the shape of the nose cone has a significant effect on the drag of the vehicle. In this paper, the concept of morphing nose cone is proposed to reduce the drag when the reentry vehicle flies back into the atmosphere. The conceptual design of the structure of morphing nose cone is conducted. Mechanical design and optimization approach are developed by employing genetic algorithm to find the optimal geometric parameters of the morphing structure. An example is analyzed by using the proposed method. The results show that optimal solution supplies the minimum position error. The concept of morphing nose cone will provide a novel way for the drag reduction of reentry vehicle. The proposed method could be practically used for the design and optimization of the deployable structure of morphing nose cone.

  12. A tandem parallel plate analyzer

    International Nuclear Information System (INIS)

    Hamada, Y.; Fujisawa, A.; Iguchi, H.; Nishizawa, A.; Kawasumi, Y.

    1996-11-01

    By a new modification of a parallel plate analyzer the second-order focus is obtained in an arbitrary injection angle. This kind of an analyzer with a small injection angle will have an advantage of small operational voltage, compared to the Proca and Green analyzer where the injection angle is 30 degrees. Thus, the newly proposed analyzer will be very useful for the precise energy measurement of high energy particles in MeV range. (author)

  13. What Is Mitochondrial DNA?

    Science.gov (United States)

    ... DNA What is mitochondrial DNA? What is mitochondrial DNA? Although most DNA is packaged in chromosomes within ... proteins. For more information about mitochondria and mitochondrial DNA: Molecular Expressions, a web site from the Florida ...

  14. Deployment and Dehumanization: A Multi-Method Study of Combat Soldiers’ Loss of Empathy

    DEFF Research Database (Denmark)

    Brænder, Morten

    2015-01-01

    Studies in soldier motivation and socialization have shown that servicemen's level of compassion decreases following deployment to war. This may to some extent be explained by the transgressive nature of the combat soldier's service : the soldier puts himself in harm's way, and must if necessary...... kill the enemy. Hence, a certain 'emotional distance' may be required for him to cope with deployment life. To kill the enemy, it might be necessary for the soldier to deprive the enemy of his human capacities, to dehumanize him. However, by combining quantitative and qualitative methods, this study...... suggests that the enemy is not the only one who is dehumanized. The data analyzed were collected immediately before and after deployment of Danish combat soldiers to Helmand, Afghanistan. Quantitative findings show that the soldiers' empathetic motivation to serve civilians, compatriots and other soldiers...

  15. Optimizing small cell deployment by the use of C-RANs

    DEFF Research Database (Denmark)

    Checko, Aleksandra; Holm, Henrik Laumand; Christiansen, Henrik Lehrmann

    2014-01-01

    A Cloud Radio Access Network (C-RAN) is a novel mobile network architecture that has the potential to support extremely dense mobile network deployments enhancing the network capacity while offering cost savings on baseband resources. In this work we analyze cell traffic profiles and evaluate...... the conditions that impact the statistical multiplexing gain in the Baseband Unit (BBU) Pool. We conclude on the set of parameters that maximize the statistical multiplexing gain, leading to the highest potential cost savings. We then propose a packet based architecture that can adapt to changing traffic...... conditions. Furthermore, based on theoretical calculations and Network simulations we present considerations on deployment scenarios to optimize green field deployments in terms of Total Cost of Ownership (TCO). This involves optimizing the mix of cells with different traffic profiles and the BBU Pool...

  16. Farm Deployable Microbial Bioreactor for Fuel Ethanol Production

    Energy Technology Data Exchange (ETDEWEB)

    Okeke, Benedict [Auburn Univ., Montgomery AL (United States)

    2016-03-30

    Research was conducted to develop a farm and field deployable microbial bioreactor for bioethanol production from biomass. Experiments were conducted to select the most efficient microorganisms for conversion of plant fiber to sugars for fermentation to ethanol. Mixtures of biomass and surface soil samples were collected from selected sites in Alabama black belt counties (Macon, Sumter, Choctaw, Dallas, Montgomery, Lowndes) and other areas within the state of Alabama. Experiments were conducted to determine the effects of culture parameters on key biomass saccharifying enzymes (cellulase, beta-glucosidase, xylanase and beta-xylosidase). A wide-scale sampling of locally-grown fruits in Central Alabama was embarked to isolate potential xylose fermenting microorganisms. Yeast isolates were evaluated for xylose fermentation. Selected microorganisms were characterized by DNA based methods. Factors affecting enzyme production and biomass saccharification were examined and optimized in the laboratory. Methods of biomass pretreatment were compared. Co-production of amylolytic enzymes with celluloytic-xylanolytic enzymes was evaluated; and co-saccharification of a combination of biomass, and starch-rich materials was examined. Simultaneous saccharification and fermentation with and without pre-saccharifcation was studied. Whole culture broth and filtered culture broth simultaneous saccahrifcation and fermentation were compared. A bioreactor system was designed and constructed to employ laboratory results for scale up of biomass saccharification.

  17. Alignment and phasing of deployable telescopes

    Science.gov (United States)

    Woolf, N. J.; Ulich, B. L.

    1983-01-01

    The experiences in coaligning and phasing the Multi-Mirror Telescope (MMT), together with studies in setting up radio telescopes, are presented. These experiences are discussed, and on the basis they furnish, schemes are suggested for coaligning and phasing four large future telescopes with complex primary mirror systems. These telescopes are MT2, a 15-m-equivalent MMT, the University of California Ten Meter Telescope, the 10 m sub-mm wave telescope of the University of Arizona and the Max Planck Institute for Radioastronomy, and the Large Deployable Reflector, a future space telescope for far-IR and sub-mm waves.

  18. Large Deployable Reflector (LDR) feasibility study update

    Science.gov (United States)

    Alff, W. H.; Banderman, L. W.

    1983-01-01

    In 1982 a workshop was held to refine the science rationale for large deployable reflectors (LDR) and develop technology requirements that support the science rationale. At the end of the workshop, a set of LDR consensus systems requirements was established. The subject study was undertaken to update the initial LDR study using the new systems requirements. The study included mirror materials selection and configuration, thermal analysis, structural concept definition and analysis, dynamic control analysis and recommendations for further study. The primary emphasis was on the dynamic controls requirements and the sophistication of the controls system needed to meet LDR performance goals.

  19. Quality function deployment: application to rehabilitation services.

    Science.gov (United States)

    Einspruch, E M; Omachonu, V K; Einspruch, N G

    1996-01-01

    Describes how the challenge of providing rehabilitative services at reasonable costs is beginning to mount. The management of quality in rehabilitative services is therefore gaining increasing attention in the health care arena. States that if a link is implied between the above stated goal and customer satisfaction, it is imperative to evaluate quality or customer satisfaction in the context of the patient's experience. Describes the quality function deployment (QFD) system and how it leads to a better understanding of the customer's needs and wants. Explores the process of applying the concept of QFD to physical therapy.

  20. Pre-deployment dissociation and personality as risk factors for post-deployment post-traumatic stress disorder in Danish soldiers deployed to Afghanistan

    DEFF Research Database (Denmark)

    Ponce de León, Beatriz; Andersen, Søren; Karstoft, Karen Inge

    2018-01-01

    Objective: This study investigated whether pre-deployment dissociation was associated with previously identified post-traumatic stress disorder (PTSD) symptom trajectories from before to 2.5 years after military deployment. Furthermore, it examined whether the tendency to dissociate, pre-deployme......Objective: This study investigated whether pre-deployment dissociation was associated with previously identified post-traumatic stress disorder (PTSD) symptom trajectories from before to 2.5 years after military deployment. Furthermore, it examined whether the tendency to dissociate, pre...

  1. Development Strategies for Deployment of Biomass Resources in the Production of Biomass Power: November 6, 2001--February 28, 2003

    Energy Technology Data Exchange (ETDEWEB)

    Kaminsky, J.

    2004-01-01

    The study analyzes strategies for deployment of biomass resources for biopower generation. It compares biomass supply databases and the projected biopower market penetration for several alternative incentive scenarios. It analyzes the availability of biomass to meet the projected market demands and recommends future research.

  2. Development and modeling of self-deployable structures

    Science.gov (United States)

    Neogi, Depankar

    Deployable space structures are prefabricated structures which can be transformed from a closed, compact configuration to a predetermined expanded form in which they are stable and can bear loads. The present research effort investigates a new family of deployable structures, called the Self-Deployable Structures (SDS). Unlike other deployable structures, which have rigid members, the SDS members are flexible while the connecting joints are rigid. The joints store the predefined geometry of the deployed structure in the collapsed state. The SDS is stress-free in both deployed and collapsed configurations and results in a self-standing structure which acquires its structural properties after a chemical reaction. Reliability of deployment is one of the most important features of the SDS, since it does not rely on mechanisms that can lock during deployment. The unit building block of these structures is the self-deployable structural element (SDSE). Several SDSE members can be linked to generate a complex building block such as a triangular or a tetrahedral structure. Different SDSE and SDS concepts are investigated in the research work, and the performance of SDS's are experimentally and theoretically explored. Triangular and tetrahedral prototype SDS have been developed and presented. Theoretical efforts include modeling the behavior of 2-dimensional SDSs. Using this design tool, engineers can study the effects of different packing configurations and deployment sequence; and perform optimization on the collapsed state of a structure with different external constraints. The model also predicts if any lockup or entanglement occurs during deployment.

  3. The effect of military deployment on mental health

    DEFF Research Database (Denmark)

    Lyk-Jensen, Stéphanie; Weatherall, Cecilie Dohlmann; W. Jepsen, Peter

    for the non-deployed eligible men, and our results hold to various robustness checks. Our administrative records provide objective measures of mental health service use in the form of psychiatric diagnoses and purchase of mental health-related medication. The very rich data makes it possible to control......In this paper we estimate the causal effect of military deployment on soldiers’ mental health. To handle the selection bias problem, we use longitudinal data for deployed and non-deployed eligible men in a difference-in-differences setting. Using pair-wise matching, we impute deployment dates...... for important variables like intelligence tests and family background. We find significant adverse effects of military deployment on soldiers’ mental health service use. Highlights: - Causal effect of military deployment on soldiers’ use of mental health service - Using a difference-in-differences approach...

  4. Heterogeneous Deployment Analysis for Cost-Effective Mobile Network Evolution

    DEFF Research Database (Denmark)

    Coletti, Claudio

    2013-01-01

    network coverage and boosting network capacity in traffic hot-spot areas. The thesis deals with the deployment of both outdoor small cells and indoor femto cells. Amongst the outdoor solution, particular emphasis is put on relay base stations as backhaul costs can be reduced by utilizing LTE spectrum...... statistical models of deployment areas, the performance analysis is carried out in the form of operator case studies for large-scale deployment scenarios, including realistic macro network layouts and inhomogeneous spatial traffic distributions. Deployment of small cells is performed by means of proposed...... heuristic deployment algorithms, which combine network coverage and spatial user density information. As a secondary aspect, deployment solutions achieving the same coverage performance are compared in terms of Total Cost of Ownership (TCO), in order to investigate the viability of different deployment...

  5. Integrated assessment of dispersed energy resources deployment

    Energy Technology Data Exchange (ETDEWEB)

    Marnay, Chris; Blanco, Raquel; Hamachi, Kristina S.; Kawaan, Cornelia P.; Osborn, Julie G.; Rubio, F. Javier

    2000-06-01

    The goal of this work is to create an integrated framework for forecasting the adoption of distributed energy resources (DER), both by electricity customers and by the various institutions within the industry itself, and for evaluating the effect of this adoption on the power system, particularly on the overall reliability and quality of electrical service to the end user. This effort and follow on contributions are intended to anticipate and explore possible patterns of DER deployment, thereby guiding technical work on microgrids towards the key technical problems. An early example of this process addressed is the question of possible DER adopting customer disconnection. A deployment scenario in which many customers disconnect from their distribution company (disco) entirely leads to a quite different set of technical problems than a scenario in which customers self generate a significant share or all of their on-site electricity requirements and additionally buy and sell energy and ancillary services (AS) locally and/or into wider markets. The exploratory work in this study suggests that the economics under which customers disconnect entirely are unlikely.

  6. SMUD Community Renewable Energy Deployment Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Sison-Lebrilla, Elaine [Sacramento Municipal Utility District, Sacramento, CA (United States); Tiangco, Valentino [Sacramento Municipal Utility District, Sacramento, CA (United States); Lemes, Marco [Sacramento Municipal Utility District, Sacramento, CA (United States); Ave, Kathleen [Sacramento Municipal Utility District, Sacramento, CA (United States)

    2015-06-08

    This report summarizes the completion of four renewable energy installations supported by California Energy Commission (CEC) grant number CEC Grant PIR-11-005, the US Department of Energy (DOE) Assistance Agreement, DE-EE0003070, and the Sacramento Municipal Utility District (SMUD) Community Renewable Energy Deployment (CRED) program. The funding from the DOE, combined with funding from the CEC, supported the construction of a solar power system, biogas generation from waste systems, and anaerobic digestion systems at dairy facilities, all for electricity generation and delivery to SMUD’s distribution system. The deployment of CRED projects shows that solar projects and anaerobic digesters can be successfully implemented under favorable economic conditions and business models and through collaborative partnerships. This work helps other communities learn how to assess, overcome barriers, utilize, and benefit from renewable resources for electricity generation in their region. In addition to reducing GHG emissions, the projects also demonstrate that solar projects and anaerobic digesters can be readily implemented through collaborative partnerships. This work helps other communities learn how to assess, overcome barriers, utilize, and benefit from renewable resources for electricity generation in their region.

  7. Dynamic analysis of the large deployable reflector

    Science.gov (United States)

    Calleson, Robert E.; Scott, A. Don

    1987-01-01

    The Large Deployable Reflector (LDR) is to be an astronomical observatory orbiting above Earth's obscuring atmosphere and operating in the spectral range between 30 microns and 1000 microns wavelength. The LDR will be used to study such astronomical phenomena as stellar and galactic formation, cosmology, and planetary atmospheres. The LDR will be the first observatory to be erected and assembled in space. This distinction brings with it several major technological challenges such as the development of ultra-lightweight deployable mirrors, advanced mirror fabrication techniques, advanced structures, and control of vibrations due to various sources of excitation. The purpose of this analysis is to provide an assessment of the vibrational response due to secondary mirror chopping and LDR slewing. The dynamic response of two 20-m LDR configurations was studied. Two mirror support configurations were investigated for the Ames concept, the first employs a six-strut secondary mirror support structure, while the second uses a triple-bipod support design. All three configurations were modeled using a tetrahedral truss design for the primary mirror support structure. Response resulting from secondary mirror chopping was obtained for the two Ames configurations, and the response of the primary mirror from slewing was obtained for all three configurations.

  8. Scenario study on the FBR deployment

    International Nuclear Information System (INIS)

    Ono, Kiyoshi; Kofuji, Hirohide; Otaki, Akira; Yonezawa, Shigeaki; Shinoda, Yoshihiko; Hirao, Kazunori; Ikegami, Tetsuo

    2000-12-01

    This study on success scenarios for the Fast Breeder Reactor (FBR) deployment was performed taking account of future situation of fossil, renewable and nuclear energies in Japan as well as the world from the viewpoints of the following four items; economics, environment, energy security and restriction of natural uranium resources. In the economics scenario, if carbon tax is added to generating cost of LNG, coal and oil and the economics of FBR cycle is competitive with LWR cycle in the future, FBR cycle will be expected to introduce as the middle and base load power plant. In the environment scenario, there is also any possibility that FBR cycle which can burn and transmute minor actinide and fission product elements will be introduced in order to reduce the burden of deposit facility and the toxicity of high-level waste. In the uranium resources restriction scenario, FBR cycle needs to be deployed at the latest in the middle of 21st century from the viewpoint of the restriction of natural uranium resources. This study was carried out in a part of JNC's feasibility study on commercialized FBR cycle system. (author)

  9. The medical software quality deployment method.

    Science.gov (United States)

    Hallberg, N; Timpka, T; Eriksson, H

    1999-03-01

    The objective of this study was to develop a Quality Function Deployment (QFD) model for design of information systems in health-care environments. Consecutive blocked-subject case studies were conducted, based on action research methods. Starting with a QFD model for software development, a model for information system design, the Medical Software Quality Deployment (MSQD) model, was developed. The MSQD model was divided into the pre-study phase, in which the customer categories and their power to influence the design are determined; the data collection phase, in which the voice of customers (VoC) is identified by observations and interviews and quantified by Critical. Incident questionnaires; the need specification phase, where the VoC is specified into ranked customer needs; and the design phase where the customer needs are transformed stepwise to technical requirements and design attributes. QFD showed to be useful for integrating the values of different customer categories in software development for health-care settings. In the later design phases, other quality methods should be used for software implementation and testing.

  10. Digital Multi Channel Analyzer Enhancement

    International Nuclear Information System (INIS)

    Gonen, E.; Marcus, E.; Wengrowicz, U.; Beck, A.; Nir, J.; Sheinfeld, M.; Broide, A.; Tirosh, D.

    2002-01-01

    A cement analyzing system based on radiation spectroscopy had been developed [1], using novel digital approach for real-time, high-throughput and low-cost Multi Channel Analyzer. The performance of the developed system had a severe problem: the resulted spectrum suffered from lack of smoothness, it was very noisy and full of spikes and surges, therefore it was impossible to use this spectrum for analyzing the cement substance. This paper describes the work carried out to improve the system performance

  11. PM 3655 PHILIPS Logic analyzer

    CERN Multimedia

    A logic analyzer is an electronic instrument that captures and displays multiple signals from a digital system or digital circuit. A logic analyzer may convert the captured data into timing diagrams, protocol decodes, state machine traces, assembly language, or may correlate assembly with source-level software. Logic Analyzers have advanced triggering capabilities, and are useful when a user needs to see the timing relationships between many signals in a digital system.

  12. Testing the Deployment Repeatability of a Precision Deployable Boom Prototype for the Proposed SWOT Karin Instrument

    Science.gov (United States)

    Agnes, Gregory S.; Waldman, Jeff; Hughes, Richard; Peterson, Lee D.

    2015-01-01

    NASA's proposed Surface Water Ocean Topography (SWOT) mission, scheduled to launch in 2020, would provide critical information about Earth's oceans, ocean circulation, fresh water storage, and river discharge. The mission concept calls for a dual-antenna Ka-band radar interferometer instrument, known as KaRIn, that would map the height of water globally along two 50 km wide swaths. The KaRIn antennas, which would be separated by 10 meters on either side of the spacecraft, would need to be precisely deployable in order to meet demanding pointing requirements. Consequently, an effort was undertaken to design build and prototype a precision deployable Mast for the KaRIn instrument. Each mast was 4.5-m long with a required dilitation stability of 2.5 microns over 3 minutes. It required a minimum first mode of 7 Hz. Deployment repeatability was less than +/- 7 arcsec in all three rotation directions. Overall mass could not exceed 41.5 Kg including any actuators and thermal blanketing. This set of requirements meant the boom had to be three times lighter and two orders of magnitude more precise than the existing state of the art for deployable booms.

  13. Child maltreatment among U.S. Air Force parents deployed in support of Operation Iraqi Freedom/Operation Enduring Freedom.

    Science.gov (United States)

    Rabenhorst, Mandy M; McCarthy, Randy J; Thomsen, Cynthia J; Milner, Joel S; Travis, Wendy J; Colasanti, Marie P

    2015-02-01

    This study examined child maltreatment perpetration among 99,697 active-duty U.S. Air Force parents who completed a combat deployment. Using the deploying parent as the unit of analysis, we analyzed whether child maltreatment rates increased postdeployement relative to predeployment. These analyses extend previous research that used aggregate data and extend our previous work that used data from the same period but used the victim as the unit of analysis and included only deploying parents who engaged in child maltreatment. In this study, 2% (n = 1,746) of deploying parents perpetrated child maltreatment during the study period. Although no overall differences were found in child maltreatment rates postdeployment compared to predeployment, several maltreatment-related characteristics qualified this finding. Rates for emotional abuse and mild maltreatment were lower following deployment, whereas child maltreatment rates for severe maltreatment were higher following deployment. The finding that rates of severe child maltreatment, including incidents involving alcohol use, were higher postdeployment suggests a need for additional support services for parents following their return from combat deployment, with a focus on returning parents who have an alcohol use problem. © The Author(s) 2014.

  14. Recovery of DNA for forensic analysis from lip cosmetics.

    Science.gov (United States)

    Webb, L G; Egan, S E; Turbett, G R

    2001-11-01

    To obtain a reference DNA profile from a missing person, we analyzed a variety of personal effects, including two lip cosmetics, both of which gave full DNA profiles. Further investigations were undertaken to explore this previously unreported source of DNA. We have tested a range of brands and types of lip cosmetics. Our studies have revealed that lip cosmetics are an excellent source of DNA, with almost 80% of samples giving a result. However, artifacts are frequently observed in the DNA profiles when Chelex is used for the DNA extraction and additional DNA purification procedures are required to ensure that an accurate DNA profile is obtained.

  15. FloorNet: Deployment and Evaluation of a Multihop Wireless 802.11 Testbed

    Directory of Open Access Journals (Sweden)

    Zink Michael

    2010-01-01

    Full Text Available A lot of attention has been given to multihop wireless networks lately, but further research—in particular, through experimentation—is needed. This attention has motivated an increase in the number of 802.11-based deployments, both indoor and outdoor. These testbeds, which require a significant amount of resources during both deployment and maintenance, are used to run measurements in order to analyze and understand the limitation and differences between analytical or simulation-based figures and the results from real-life experimentation. This paper makes two major contributions: (i first, we describe a novel wireless multihop testbed, which we name FloorNet, that is deployed and operated under the false floor of a lab in our Computer Science building. This false floor provides a strong physical protection that prevents disconnections or misplacements, as well as radio shielding (to some extent thanks to the false floor panels—this later feature is assessed through experimentation; (ii second, by running exhaustive and controlled experiments we are able to analyze the performance limits of commercial off-the-shelf hardware, as well as to derive practical design criteria for the deployment and configuration of mesh networks. These results both provide valuable insights of wireless multihop performance and prove that FloorNet constitutes a valuable asset to research on wireless mesh networks.

  16. Evaluation of Deployment Challenges of Wireless Sensor Networks at Signalized Intersections

    Directory of Open Access Journals (Sweden)

    Leyre Azpilicueta

    2016-07-01

    Full Text Available With the growing demand of Intelligent Transportation Systems (ITS for safer and more efficient transportation, research on and development of such vehicular communication systems have increased considerably in the last years. The use of wireless networks in vehicular environments has grown exponentially. However, it is highly important to analyze radio propagation prior to the deployment of a wireless sensor network in such complex scenarios. In this work, the radio wave characterization for ISM 2.4 GHz and 5 GHz Wireless Sensor Networks (WSNs deployed taking advantage of the existence of traffic light infrastructure has been assessed. By means of an in-house developed 3D ray launching algorithm, the impact of topology as well as urban morphology of the environment has been analyzed, emulating the realistic operation in the framework of the scenario. The complexity of the scenario, which is an intersection city area with traffic lights, vehicles, people, buildings, vegetation and urban environment, makes necessary the channel characterization with accurate models before the deployment of wireless networks. A measurement campaign has been conducted emulating the interaction of the system, in the vicinity of pedestrians as well as nearby vehicles. A real time interactive application has been developed and tested in order to visualize and monitor traffic as well as pedestrian user location and behavior. Results show that the use of deterministic tools in WSN deployment can aid in providing optimal layouts in terms of coverage, capacity and energy efficiency of the network.

  17. DNA Vaccines

    Indian Academy of Sciences (India)

    diseases. Keywords. DNA vaccine, immune response, antibodies, infectious diseases. GENERAL .... tein vaccines require expensive virus/protein purification tech- niques as ... sphere continue to remain major health hazards in developing nations. ... significance since it can be produced at a very low cost and can be stored ...

  18. DNA Investigations.

    Science.gov (United States)

    Mayo, Ellen S.; Bertino, Anthony J.

    1991-01-01

    Presents a simulation activity that allow students to work through the exercise of DNA profiling and to grapple with some analytical and ethical questions involving a couple arranging with a surrogate mother to have a baby. Can be used to teach the principles of restriction enzyme digestion, gel electrophoresis, and probe hybridization. (MDH)

  19. Multichannel analyzer type CMA-3

    International Nuclear Information System (INIS)

    Czermak, A.; Jablonski, J.; Ostrowicz, A.

    1978-01-01

    Multichannel analyzer CMA-3 is designed for two-parametric analysis with operator controlled logical windows. It is implemented in CAMAC standard. A single crate contains all required modules and is controlled by the PDP-11/10 minicomputer. Configuration of CMA-3 is shown. CMA-3 is the next version of the multichannel analyzer described in report No 958/E-8. (author)

  20. Analyzing data files in SWAN

    CERN Document Server

    Gajam, Niharika

    2016-01-01

    Traditionally analyzing data happens via batch-processing and interactive work on the terminal. The project aims to provide another way of analyzing data files: A cloud-based approach. It aims to make it a productive and interactive environment through the combination of FCC and SWAN software.

  1. Finding Their Way Back In: Family Reintegration Following Guard Deployment.

    Science.gov (United States)

    Messecar, Deborah C

    2017-03-01

    The aim of this study was to describe deployed National Guard members' and their families' perceptions of their experience with family reintegration, and the causes and conditions of challenges reintegration presents after deployment. A total of 26 National Guard members and 19 family members participated in individual (n = 22), couples (n = 6), or focus group (n = 17) interviews. In-depth interviews were used to assess needs and maximize input from military families regarding deployment-related experiences and reintegration issues. Qualitative coding and analysis of data were completed using NVivo. Finding their way back in is the key process that the military members must complete to successfully reestablish their desired social connections with the family and reclaim their place within the family. Several conditions shape the degree of challenges with reintegration that veterans and their family will encounter. These include preparation for deployment, length and type of deployment, communication during deployment, and finally, awareness of how deployment changes the military member and the family. Support resources dedicated to providing National Guard members and their families with assistance in preparing for deployments and educating them about the importance of communication during deployment should be maintained and expanded. Broader educational efforts that increase awareness of what to expect regarding how deployment changes the military member and the family are needed. Reprint & Copyright © 2017 Association of Military Surgeons of the U.S.

  2. Deployment and Evaluation of an Observations Data Model

    Science.gov (United States)

    Horsburgh, J. S.; Tarboton, D. G.; Zaslavsky, I.; Maidment, D. R.; Valentine, D.

    2007-12-01

    Environmental observations are fundamental to hydrology and water resources, and the way these data are organized and manipulated either enables or inhibits the analyses that can be performed. The CUAHSI Hydrologic Information System project is developing information technology infrastructure to support hydrologic science. This includes an Observations Data Model (ODM) that provides a new and consistent format for the storage and retrieval of environmental observations in a relational database designed to facilitate integrated analysis of large datasets collected by multiple investigators. Within this data model, observations are stored with sufficient ancillary information (metadata) about the observations to allow them to be unambiguously interpreted and used, and to provide traceable heritage from raw measurements to useable information. The design is based upon a relational database model that exposes each single observation as a record, taking advantage of the capability in relational database systems for querying based upon data values and enabling cross dimension data retrieval and analysis. This data model has been deployed, as part of the HIS Server, at the WATERS Network test bed observatories across the U.S where it serves as a repository for real time data in the observatory information system. The ODM holds the data that is then made available to investigators and the public through web services and the Data Access System for Hydrology (DASH) map based interface. In the WATERS Network test bed settings the ODM has been used to ingest, analyze and publish data from a variety of sources and disciplines. This paper will present an evaluation of the effectiveness of this initial deployment and the revisions that are being instituted to address shortcomings. The ODM represents a new, systematic way for hydrologists, scientists, and engineers to organize and share their data and thereby facilitate a fuller integrated understanding of water resources based on

  3. Field-Deployable Acoustic Digital Systems for Noise Measurement

    Science.gov (United States)

    Shams, Qamar A.; Wright, Kenneth D.; Lunsford, Charles B.; Smith, Charlie D.

    2000-01-01

    Langley Research Center (LaRC) has for years been a leader in field acoustic array measurement technique. Two field-deployable digital measurement systems have been developed to support acoustic research programs at LaRC. For several years, LaRC has used the Digital Acoustic Measurement System (DAMS) for measuring the acoustic noise levels from rotorcraft and tiltrotor aircraft. Recently, a second system called Remote Acquisition and Storage System (RASS) was developed and deployed for the first time in the field along with DAMS system for the Community Noise Flight Test using the NASA LaRC-757 aircraft during April, 2000. The test was performed at Airborne Airport in Wilmington, OH to validate predicted noise reduction benefits from alternative operational procedures. The test matrix was composed of various combinations of altitude, cutback power, and aircraft weight. The DAMS digitizes the acoustic inputs at the microphone site and can be located up to 2000 feet from the van which houses the acquisition, storage and analysis equipment. Digitized data from up to 10 microphones is recorded on a Jaz disk and is analyzed post-test by microcomputer system. The RASS digitizes and stores acoustic inputs at the microphone site that can be located up to three miles from the base station and can compose a 3 mile by 3 mile array of microphones. 16-bit digitized data from the microphones is stored on removable Jaz disk and is transferred through a high speed array to a very large high speed permanent storage device. Up to 30 microphones can be utilized in the array. System control and monitoring is accomplished via Radio Frequency (RF) link. This paper will present a detailed description of both systems, along with acoustic data analysis from both systems.

  4. QUALITY FUNCTION DEPLOYMENT AS A STRATEGIC PLANNINGTOOL

    Directory of Open Access Journals (Sweden)

    Burcu DEVRİM İÇTENBAŞ

    2011-07-01

    Full Text Available Quality Function Deployment (QFD uses a house of quality to translate customerrequirements into engineering specifications. QFD has been widely used as a toolto develop new products. It has been adopted in thefields of education quality,service quality, software development and marketingplanning. The tool hasrecently been applied in strategic planning .In this study authors reviewed currentresearch which uses QFD as a strategic planning tool and described how QFDmethods can be used as a robust tool in strategic planning. This study provides aninsight for strategic planners to utilize a QFD- based philosophy and the methodsare useful tools for the design of a customer-driven strategy and show how itsystematically translates vision into action, targeting opportunities and creatinginnovative strategies.

  5. OpenFlow Deployment and Concept Analysis

    Directory of Open Access Journals (Sweden)

    Tomas Hegr

    2013-01-01

    Full Text Available Terms such as SDN and OpenFlow (OF are often used in the research and development of data networks. This paper deals with the analysis of the current state of OpenFlow protocol deployment options as it is the only real representative protocol that enables the implementation of Software Defined Networking outside an academic world. There is introduced an insight into the current state of the OpenFlow specification development at various levels is introduced. The possible limitations associated with this concept in conjunction with the latest version (1.3 of the specification published by ONF are also presented. In the conclusion there presented a demonstrative security application addressing the lack of IPv6 support in real network devices since most of today's switches and controllers support only OF v1.0.

  6. Stochastic Optimization for Nuclear Facility Deployment Scenarios

    Science.gov (United States)

    Hays, Ross Daniel

    Single-use, low-enriched uranium oxide fuel, consumed through several cycles in a light-water reactor (LWR) before being disposed, has become the dominant source of commercial-scale nuclear electric generation in the United States and throughout the world. However, it is not without its drawbacks and is not the only potential nuclear fuel cycle available. Numerous alternative fuel cycles have been proposed at various times which, through the use of different reactor and recycling technologies, offer to counteract many of the perceived shortcomings with regards to waste management, resource utilization, and proliferation resistance. However, due to the varying maturity levels of these technologies, the complicated material flow feedback interactions their use would require, and the large capital investments in the current technology, one should not deploy these advanced designs without first investigating the potential costs and benefits of so doing. As the interactions among these systems can be complicated, and the ways in which they may be deployed are many, the application of automated numerical optimization to the simulation of the fuel cycle could potentially be of great benefit to researchers and interested policy planners. To investigate the potential of these methods, a computational program has been developed that applies a parallel, multi-objective simulated annealing algorithm to a computational optimization problem defined by a library of relevant objective functions applied to the Ver ifiable Fuel Cycle Simulati on Model (VISION, developed at the Idaho National Laboratory). The VISION model, when given a specified fuel cycle deployment scenario, computes the numbers and types of, and construction, operation, and utilization schedules for, the nuclear facilities required to meet a predetermined electric power demand function. Additionally, it calculates the location and composition of the nuclear fuels within the fuel cycle, from initial mining through

  7. Clean energy deployment: addressing financing cost

    International Nuclear Information System (INIS)

    Ameli, Nadia; Kammen, Daniel M

    2012-01-01

    New methods are needed to accelerate clean energy policy adoption. To that end, this study proposes an innovative financing scheme for renewable and energy efficiency deployment. Financing barriers represent a notable obstacle for energy improvements and this is particularly the case for low income households. Implementing a policy such as PACE—property assessed clean energy—allows for the provision of upfront funds for residential property owners to install electric and thermal solar systems and make energy efficiency improvements to their buildings. This paper will inform the design of better policies tailored to the creation of the appropriate conditions for such investments to occur, especially in those countries where most of the population belongs to the low–middle income range facing financial constraints. (letter)

  8. Lessons learnt from WLCG service deployment

    International Nuclear Information System (INIS)

    Shiers, J D

    2008-01-01

    This paper summarises the main lessons learnt from deploying WLCG production services, with a focus on Reliability, Scalability, Accountability, which lead to both manageability and usability. Each topic is analysed in turn. Techniques for zero-user-visible downtime for the main service interventions are described, together with pathological cases that need special treatment. The requirements in terms of scalability are analysed, calling for as much robustness and automation in the service as possible. The different aspects of accountability - which covers measuring/tracking/logging/monitoring what is going on - and has gone on - is examined, with the goal of attaining a manageable service. Finally, a simple analogy is drawn with the Web in terms of usability - what do we need to achieve to cross the chasm from small-scale adoption to ubiquity?

  9. Techno-Economics of Residential Broadband Deployment

    DEFF Research Database (Denmark)

    Sigurdsson, Halldor Matthias

    2007-01-01

    on account of their existing telecom network (”the raw copper”), and typically they will prefer an xDSL-based strategy (various types of Digital Subscriber Line-technology: ADSL, VDSL, etc.), where the rate of speed of data connections are increased gradually to 10-50 Mbit/s or even more, in order to gain...... broadband deployment strategy is depending on a complexed set of parameters, and there is a demand for precise techno-economic cost models estimating financial feasibility. The existing cost models do not consider the dynamic developments in the market caused by competition. The PhD thesis has a profound...... the general principles from the Danish LRAIC-model (Long Run Average Incremental Cost) and divides Denmark in 4 geografical profiles. Considering the existing copper-infrastructure the most advantageous strategies for the players of each of these profiles are identified. The importance of the time horizon...

  10. Rapid deployable global sensing hazard alert system

    Science.gov (United States)

    Cordaro, Joseph V; Tibrea, Steven L; Shull, Davis J; Coleman, Jerry T; Shuler, James M

    2015-04-28

    A rapid deployable global sensing hazard alert system and associated methods of operation are provided. An exemplary system includes a central command, a wireless backhaul network, and a remote monitoring unit. The remote monitoring unit can include a positioning system configured to determine a position of the remote monitoring unit based on one or more signals received from one or more satellites located in Low Earth Orbit. The wireless backhaul network can provide bidirectional communication capability independent of cellular telecommunication networks and the Internet. An exemplary method includes instructing at least one of a plurality of remote monitoring units to provide an alert based at least in part on a location of a hazard and a plurality of positions respectively associated with the plurality of remote monitoring units.

  11. Clean energy deployment: addressing financing cost

    Science.gov (United States)

    Ameli, Nadia; Kammen, Daniel M.

    2012-09-01

    New methods are needed to accelerate clean energy policy adoption. To that end, this study proposes an innovative financing scheme for renewable and energy efficiency deployment. Financing barriers represent a notable obstacle for energy improvements and this is particularly the case for low income households. Implementing a policy such as PACE—property assessed clean energy—allows for the provision of upfront funds for residential property owners to install electric and thermal solar systems and make energy efficiency improvements to their buildings. This paper will inform the design of better policies tailored to the creation of the appropriate conditions for such investments to occur, especially in those countries where most of the population belongs to the low-middle income range facing financial constraints.

  12. Multiple conformational states of DnaA protein regulate its interaction with DnaA boxes in the initiation of DNA replication.

    Science.gov (United States)

    Patel, Meera J; Bhatia, Lavesh; Yilmaz, Gulden; Biswas-Fiss, Esther E; Biswas, Subhasis B

    2017-09-01

    DnaA protein is the initiator of genomic DNA replication in prokaryotes. It binds to specific DNA sequences in the origin of DNA replication and unwinds small AT-rich sequences downstream for the assembly of the replisome. The mechanism of activation of DnaA that enables it to bind and organize the origin DNA and leads to replication initiation remains unclear. In this study, we have developed double-labeled fluorescent DnaA probes to analyze conformational states of DnaA protein upon binding DNA, nucleotide, and Soj sporulation protein using Fluorescence Resonance Energy Transfer (FRET). Our studies demonstrate that DnaA protein undergoes large conformational changes upon binding to substrates and there are multiple distinct conformational states that enable it to initiate DNA replication. DnaA protein adopted a relaxed conformation by expanding ~15Å upon binding ATP and DNA to form the ATP·DnaA·DNA complex. Hydrolysis of bound ATP to ADP led to a contraction of DnaA within the complex. The relaxed conformation of DnaA is likely required for the formation of the multi-protein ATP·DnaA·DNA complex. In the initiation of sporulation, Soj binding to DnaA prevented relaxation of its conformation. Soj·ADP appeared to block the activation of DnaA, suggesting a mechanism for Soj·ADP in switching initiation of DNA replication to sporulation. Our studies demonstrate that multiple conformational states of DnaA protein regulate its binding to DNA in the initiation of DNA replication. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. Time Deployment Study for Annulus Pumping

    International Nuclear Information System (INIS)

    REBERGER, D.W.

    2000-01-01

    Radioactive wastes from processing irradiated uranium fuels have been stored as alkaline slurries in underground tanks at the Hanford Site. Single-shell tanks (SST) and double-shell tanks (DST) of various sizes were used for waste storage. Of the total 177 tanks, there are 28 DSTs. DSTs are located in AN, AP, AW, AY, AZ, and SY tank farms in the 200 East (200E) and 200-West (200W) Areas. The storage capacities of the DSTs vary from 980,000 to 1,140,000 gal. DSTs are designed and constructed as an integral steel structure, i.e., an inner shell within an outer shell, so that any leak from the inner shell is confined within the annulus without impacting the environment. The inner shell provides primary containment for the wastes and the outer shell provides secondary containment in the form of an annulus. The annulus of a DST is equipped with a pump pit, leak detection probes, and other accessories. The existing annulus pumps in the DSTs need to be revamped with a new system to reduce operating costs and reduce the time to deploy a pumping system. The new pumping system will minimize the likelihood of a release of waste into the environment; improve capability of waste removal to the maximum extent possible to comply with Washington Administrative Code (WAC) 173-303-640 and Code of Federal Regulations (CFR) 40 CFR 265.193. This study addresses the time required to deploy an annulus pumping system designed to fit any DST after detection of a leak in the inner shell of the DST

  14. DNA adducts in senescent cells

    International Nuclear Information System (INIS)

    Gaubatz, J.W.

    1987-01-01

    Perturbations in DNA repair and other metabolic processes during development and aging might affect the steady-state level of genomic damage. The persistence or accumulation of DNA lesions in postmitotic cells could have a significant impact on proper cellular function, interfering with gene regulation for example. To test the notion that DNA damage increases as a function of age in non-dividing cells, DNA was purified from heart tissue of C57BL/6Nia mice at different ages and analyzed by post labeling techniques to detect DNA adducts. In the present experiments, four-dimensional, thin-layer chromatography was used to isolate aromatic adducts that were labeled with carrier-free (γ- 32 P) ATP under DNA-P excess conditions. The complexity and frequency of aromatic adducts varied between DNA samples. Several adducts were present in all preparations and were clearly more abundant in nucleotide maps of mature and old heart DNA. However, a direct correlation with age was not observed. In contrast, experiments in which aromatic adducts were first isolated by phase-transfer to 1-butanol, then labeled with excess (γ- 32 P)ATP indicated that there was an age-related increase in these adducts. The results are consistent with their earlier studies that showed alkyl adducts increased during aging of mouse myocardium and suggest that a common repair pathway might be involved

  15. [Automated analyzer of enzyme immunoassay].

    Science.gov (United States)

    Osawa, S

    1995-09-01

    Automated analyzers for enzyme immunoassay can be classified by several points of view: the kind of labeled antibodies or enzymes, detection methods, the number of tests per unit time, analytical time and speed per run. In practice, it is important for us consider the several points such as detection limits, the number of tests per unit time, analytical range, and precision. Most of the automated analyzers on the market can randomly access and measure samples. I will describe the recent advance of automated analyzers reviewing their labeling antibodies and enzymes, the detection methods, the number of test per unit time and analytical time and speed per test.

  16. The financial impact of deployments on reserve health care providers.

    Science.gov (United States)

    Petinaux, Bruno

    2008-08-01

    This study retrospectively surveyed the financial impact of deployments on 17 U.S. Army Reserve health care providers. Due to multiple mobilizations, 29 separate deployments were reported. The deployments, mostly between 2001 and 2005, typically lasted 3 months during which 86% reported no civilian income and 76% reported no civilian benefits. Solo practice providers reported the greatest financial losses due to continuing financial responsibility related to their civilian practice despite being deployed. Overall, 2 deployments did not change, 9 increased, and 16 decreased the medical officer's income. Two were not reported. In this small retrospective convenience sample study, solo practice U.S. Army Reserve health care providers were found to be at highest risk of financial losses during military deployments. This being said, no price can be put on the privilege of serving our men and women in uniform.

  17. Early identification of posttraumatic stress following military deployment

    DEFF Research Database (Denmark)

    Karstoft, Karen-Inge; Statnikov, Alexander; Andersen, Søren B

    2015-01-01

    BACKGROUND: Pre-deployment identification of soldiers at risk for long-term posttraumatic stress psychopathology after home coming is important to guide decisions about deployment. Early post-deployment identification can direct early interventions to those in need and thereby prevents...... the development of chronic psychopathology. Both hold significant public health benefits given large numbers of deployed soldiers, but has so far not been achieved. Here, we aim to assess the potential for pre- and early post-deployment prediction of resilience or posttraumatic stress development in soldiers...... by application of machine learning (ML) methods. METHODS: ML feature selection and prediction algorithms were applied to a prospective cohort of 561 Danish soldiers deployed to Afghanistan in 2009 to identify unique risk indicators and forecast long-term posttraumatic stress responses. RESULTS: Robust pre...

  18. Accounting for variation in wind deployment between Canadian provinces

    International Nuclear Information System (INIS)

    Ferguson-Martin, Christopher J.; Hill, Stephen D.

    2011-01-01

    Wind energy deployment varies widely across regions and this variation cannot be explained by differences in natural wind resources alone. Evidence suggests that institutional factors beyond physical wind resources can influence the deployment of wind energy systems. Building on the work of , this study takes a historical institutionalist approach to examine the main factors influencing wind energy deployment across four Canadian provinces Canada: Alberta, Manitoba, Ontario and Nova Scotia. Our case studies suggest that wind energy deployment depends upon a combination of indirect causal factors-landscape values, political and social movements, government electricity policy, provincial electricity market structure and incumbent generation technologies and direct causal factors-grid architecture, ownership patterns, renewable incentive programs, planning and approvals processes and stakeholder support and opposition. - Research highlights: → Examines the reasons for variations in wind deployment between Canadian provinces. → Employs a historical institutional approach to the analysis. → Discusses social factors that affect wind deployment across Canadian jurisdictions.

  19. Autonomous Deployment and Restoration of Sensor Network using Mobile Robots

    Directory of Open Access Journals (Sweden)

    Tsuyoshi Suzuki

    2010-09-01

    Full Text Available This paper describes an autonomous deployment and restoration of a Wireless Sensor Network (WSN using mobile robots. The authors have been developing an information-gathering system using mobile robots and WSNs in underground spaces in post-disaster environments. In our system, mobile robots carry wireless sensor nodes (SN and deploy them into the environment while measuring Received Signal Strength Indication (RSSI values to ensure communication, thereby enabling the WSN to be deployed and restored autonomously. If the WSN is disrupted, mobile robots restore the communication route by deploying additional or alternate SNs to suitable positions. Utilizing the proposed method, a mobile robot can deploy a WSN and gather environmental information via the WSN. Experimental results using a verification system equipped with a SN deployment and retrieval mechanism are presented.

  20. Autonomous Deployment and Restoration of Sensor Network using Mobile Robots

    Directory of Open Access Journals (Sweden)

    Tsuyoshi Suzuki

    2010-06-01

    Full Text Available This paper describes an autonomous deployment and restoration of a Wireless Sensor Network (WSN using mobile robots. The authors have been developing an information-gathering system using mobile robots and WSNs in underground spaces in post-disaster environments. In our system, mobile robots carry wireless sensor nodes (SN and deploy them into the environment while measuring Received Signal Strength Indication (RSSI values to ensure communication, thereby enabling the WSN to be deployed and restored autonomously. If the WSN is disrupted, mobile robots restore the communication route by deploying additional or alternate SNs to suitable positions. Utilizing the proposed method, a mobile robot can deploy a WSN and gather environmental information via the WSN. Experimental results using a verification system equipped with a SN deployment and retrieval mechanism are presented.

  1. Supporting Military Families with Young Children throughout the Deployment Lifecycle

    Science.gov (United States)

    2016-10-01

    Group, Family Advocacy, Child and Family Behavioral Health, Soldier Readiness Program (SRP), Family Life Chaplain Training Center, Fort Hood Housing ...resilience and child well-being, Soldier and non-deploying parents must successfully meet the challenges of caregiving throughout the deployment cycle ...reintegration program to reduce parenting stress and promote family resilience in Active Duty military families through all phases of the deployment cycle

  2. White Paper on Dish Stirling Technology: Path Toward Commercial Deployment

    Energy Technology Data Exchange (ETDEWEB)

    Andraka, Charles E. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Concentrating Solar Power Dept.; Stechel, Ellen [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Concentrating Solar Power Dept.; Becker, Peter [Stirling Energy Systems, Scottsdale, AZ (United States); Messick, Brian [Stirling Energy Systems, Scottsdale, AZ (United States)

    2016-07-01

    Dish Stirling energy systems have been developed for distributed and large-scale utility deployment. This report summarizes the state of the technology in a joint project between Stirling Energy Systems, Sandia National Laboratories, and the Department of Energy in 2011. It then lays out a feasible path to large scale deployment, including development needs and anticipated cost reduction paths that will make a viable deployment product.

  3. Self managing monitoring for highly elastic large scale Cloud deployments

    OpenAIRE

    Ward, Jonathan Stuart; Barker, Adam David

    2014-01-01

    Infrastructure as a Service computing exhibits a number of properties, which are not found in conventional server deployments. Elasticity is among the most significant of these properties which has wide reaching implications for applications deployed in cloud hosted VMs. Among the applications affected by elasticity is monitoring. In this paper we investigate the challenges of monitoring large cloud deployments and how these challenges differ from previous monitoring problems. In order to mee...

  4. DEMorphy, German Language Morphological Analyzer

    OpenAIRE

    Altinok, Duygu

    2018-01-01

    DEMorphy is a morphological analyzer for German. It is built onto large, compactified lexicons from German Morphological Dictionary. A guesser based on German declension suffixed is also provided. For German, we provided a state-of-art morphological analyzer. DEMorphy is implemented in Python with ease of usability and accompanying documentation. The package is suitable for both academic and commercial purposes wit a permissive licence.

  5. A Categorization of Dynamic Analyzers

    Science.gov (United States)

    Lujan, Michelle R.

    1997-01-01

    Program analysis techniques and tools are essential to the development process because of the support they provide in detecting errors and deficiencies at different phases of development. The types of information rendered through analysis includes the following: statistical measurements of code, type checks, dataflow analysis, consistency checks, test data,verification of code, and debugging information. Analyzers can be broken into two major categories: dynamic and static. Static analyzers examine programs with respect to syntax errors and structural properties., This includes gathering statistical information on program content, such as the number of lines of executable code, source lines. and cyclomatic complexity. In addition, static analyzers provide the ability to check for the consistency of programs with respect to variables. Dynamic analyzers in contrast are dependent on input and the execution of a program providing the ability to find errors that cannot be detected through the use of static analysis alone. Dynamic analysis provides information on the behavior of a program rather than on the syntax. Both types of analysis detect errors in a program, but dynamic analyzers accomplish this through run-time behavior. This paper focuses on the following broad classification of dynamic analyzers: 1) Metrics; 2) Models; and 3) Monitors. Metrics are those analyzers that provide measurement. The next category, models, captures those analyzers that present the state of the program to the user at specified points in time. The last category, monitors, checks specified code based on some criteria. The paper discusses each classification and the techniques that are included under them. In addition, the role of each technique in the software life cycle is discussed. Familiarization with the tools that measure, model and monitor programs provides a framework for understanding the program's dynamic behavior from different, perspectives through analysis of the input

  6. CSTT Update: Fuel Quality Analyzer

    Energy Technology Data Exchange (ETDEWEB)

    Brosha, Eric L. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Lujan, Roger W. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Mukundan, Rangachary [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Rockward, Tommy [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Romero, Christopher J. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Williams, Stefan [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Wilson, Mahlon S. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2018-02-06

    These are slides from a presentation. The following topics are covered: project background (scope and approach), developing the prototype (timeline), update on intellectual property, analyzer comparisons (improving humidification, stabilizing the baseline, applying clean-up strategy, impact of ionomer content and improving clean-up), proposed operating mode, considerations for testing in real-world conditions (Gen 1 analyzer electronics development, testing partner identified, field trial planning), summary, and future work.

  7. Novel CMS lines in pigeonpea [Cajanus cajan (L. Millspaugh] derived from cytoplasmic substitutions, and their effective restoration and deployment in hybrid breeding

    Directory of Open Access Journals (Sweden)

    Abhishek Bohra

    2017-02-01

    Full Text Available The availability of stable cytoplasmic male sterile (CMS or A lines coupled with a robust restoration system (R lines is an essential prerequisite for efficient hybrid breeding. CMS-enabled hybrid technology holds immense potential to enhance the long-stagnant productivity of pigeonpea. In the present investigation, cytoplasmic substitutions were made in the nuclear backgrounds of early-maturing pigeonpea varieties or lines. Three new CMS lines (ICPL 88039A, Pusa 992A, and DPP 3-2A resulted from genetic crosses involving cytoplasmic donors from A2 (GT 288A and A4 (ICPA 2089 categories. In addition to visual inspection of anthers, pollen-staining techniques and scanning electron microscopy (SEM analysis were used to confirm pollen sterility. Further, given the relevance of the plant mitochondrial genome to CMS manifestation, 25 mitochondrion-specific DNA markers were assayed on these newly developed A lines and isogenic maintainer (B lines. DNA polymorphism between Pusa 992A and Pusa 992B as revealed by the nad7a_del marker confirmed the successful combination of sterilizing cytoplasm (A4 and nonrestoring nuclear background (Pusa 992. Such cytoplasm-specific DNA markers are required for A2-CMS as well. Further, to assess restoration ability, potential restorers were crossed with these CMS lines, and as a consequence, promising A × R combinations exhibiting 100% pollen fertility could be identified. In parallel, we also analyzed the inheritance patterns underlying fertility restoration using ICPL 88039A-derived F2 and BC1F1 populations, and established a monogenic dominant model to explain the phenomenon of A2-CMS restoration. In summary, we report the successful development of new CMS lines and describe their effective deployment in hybrid breeding of pigeonpea.

  8. Multiobjective Shape Optimization for Deployment and Adjustment Properties of Cable-Net of Deployable Antenna

    Directory of Open Access Journals (Sweden)

    Guoqiang You

    2015-01-01

    Full Text Available Based on structural features of cable-net of deployable antenna, a multiobjective shape optimization method is proposed to help to engineer antenna’s cable-net structure that has better deployment and adjustment properties. In this method, the multiobjective optimum mathematical model is built with lower nodes’ locations of cable-net as variables, the average stress ratio of cable elements and strain energy as objectives, and surface precision and natural frequency of cable-net as constraints. Sequential quadratic programming method is used to solve this nonlinear mathematical model in conditions with different weighting coefficients, and the results show the validity and effectiveness of the proposed method and model.

  9. Verification Test for Ultra-Light Deployment Mechanism for Sectioned Deployable Antenna Reflectors

    Science.gov (United States)

    Zajac, Kai; Schmidt, Tilo; Schiller, Marko; Seifart, Klaus; Schmalbach, Matthias; Scolamiero, Lucio

    2013-09-01

    The ultra-light deployment mechanism (UDM) is based on three carbon fibre reinforced plastics (CFRP) curved tape springs made of carbon fibre / cyanate ester prepregs.In the frame of the activity its space application suitability for the deployment of solid reflector antenna sections was investigated. A projected diameter of the full reflector of 4 m to 7 m and specific mass in the order of magnitude of 2.6kg/m2 was focused for requirement derivation.Extensive verification tests including health checks, environmental and functional tests were carried out with an engineering model to enable representative characterizing of the UDM unit.This paper presents the design and a technical description of the UDM as well as a summary of achieved development status with respect to test results and possible design improvements.

  10. DNA repair

    International Nuclear Information System (INIS)

    Setlow, R.

    1978-01-01

    Some topics discussed are as follows: difficulty in extrapolating data from E. coli to mammalian systems; mutations caused by UV-induced changes in DNA; mutants deficient in excision repair; other postreplication mechanisms; kinds of excision repair systems; detection of repair by biochemical or biophysical means; human mutants deficient in repair; mutagenic effects of UV on XP cells; and detection of UV-repair defects among XP individuals

  11. Market and Policy Barriers to Energy Storage Deployment

    Energy Technology Data Exchange (ETDEWEB)

    Bhatnagar, Dhruv [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Currier, Aileen [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Hernandez, Jacquelynne [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Ma, Ookie [Dept. of Energy (DOE), Washington DC (United States) Office of Energy Efficiency and Renewable Energy; Kirby, Brendan [Consultant

    2013-09-01

    Electric energy storage technologies can provide numerous grid services; there are a number of factors that restrict their current deployment. The most significant barrier to deployment is high capital costs, though several recent deployments indicate that capital costs are decreasing and energy storage may be the preferred economic alternative in certain situations. However, a number of other market and regulatory barriers persist, limiting further deployment. These barriers can be categorized into regulatory barriers, market (economic) barriers, utility and developer business model barriers, cross-cutting barriers and technology barriers.

  12. LWR Spent Fuel Management for the Smooth Deployment of FBR

    International Nuclear Information System (INIS)

    Fukasawa, T.; Yamashita, J.; Hoshino, K.; Sasahira, A.; Inoue, T.; Minato, K.; Sato, S.

    2015-01-01

    Fast breeder reactors (FBR) and FBR fuel cycle are indispensable to prevent the global warming and to secure the long-term energy supply. Commercial FBR expects to be deployed from around 2050 until around 2110 in Japan by the replacement of light water reactors (LWR) after their 60 years life. The FBR deployment needs Pu (MOX) from the LWR-spent fuel (SF) reprocessing. As Japan can posses little excess Pu, its balance control is necessary between LWR-SF management (reprocessing) and FBR deployment. The fuel cycle systems were investigated for the smooth FBR deployment and the effectiveness of proposed flexible system was clarified in this work. (author)

  13. Human Metabolism and Interactions of Deployment-Related Chemicals

    National Research Council Canada - National Science Library

    Hodgson, Ernest

    2003-01-01

    This study examines the human-metabolism and metabolic interactions of a subset of deployment-related chemicals, including chlorpyrifos, DEET, permethrin, pyridostigmine bromide, and sulfur mustard metabolites...

  14. Rapidly Evolving Distributed Systems by Bridging the Deployment Gap

    National Research Council Canada - National Science Library

    Wolf, Alexander

    2000-01-01

    .... The University of Colorado EDCS project has been successful in achieving its objective: producing innovative, useful, and interesting research results in the areas of software configuration and deployment...

  15. Rapidly Evolving Distributed Systems by Bridging the Deployment Gap

    National Research Council Canada - National Science Library

    Wolf, Alexander

    2001-01-01

    .... The University of Colorado EDCS project has been successful in achieving its objective; producing innovative, useful and interesting research results in the areas of software configuration and deployment...

  16. Deployment Testing of the De-Orbit Sail Flight Hardware

    OpenAIRE

    Hillebrandt, Martin; Meyer, Sebastian; Zander, Martin; Hühne, Christian

    2015-01-01

    The paper describes the results of the deployment testing of the De-Orbit Sail flight hardware, a drag sail for de-orbiting applications, performed by DLR. It addresses in particular the deployment tests of the fullscale sail subsystem and deployment force tests performed on the boom deployment module. For the fullscale sail testing a gravity compensation device is used which is described in detail. It allows observations of the in-plane interaction of the booms with the sail membrane and the...

  17. Six policy actions for accelerated deployment of renewable energy. READy Renewable Energy Action on Deployment. Summary

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-03-15

    The READy book presents a kaleidoscope of policy options that have proven to accelerate the deployment of renewable energy technologies, based on experiences around the world at the local and national levels. Lessons learned from successful cases are distilled into six essential action points. Together these categories of policy actions compose the ACTION Star, a guide for taking action now while preparing for growth over the long term.

  18. The Deployment Life Study: Longitudinal Analysis of Military Families Across the Deployment Cycle

    Science.gov (United States)

    2016-01-01

    deployment. The 11 events, grouped by type of trauma, are as follows: • combat – engaging in hand-to-hand combat – being physically knocked over...leaving home; missing classes at school because you don’t like your school; missing after-school activities (such as school activities, sports ) because...you don’t feel like participating; missing after-school activities (such as school activi- ties, sports ) because of transportation problems/issues

  19. Swarm Deployable Boom Assembly (DBA) Development of a Deployable Magnetometer Boom for the Swarm Spacecraft

    Science.gov (United States)

    McMahon, Paul; Jung, Hans-Juergen; Edwards, Jeff

    2013-09-01

    The Swarm programme consists of 3 magnetically clean satellites flying in close formation designed to measure the Earth's magnetic field using 2 Magnetometers mounted on a 4.3m long deployable boom.Deployment is initiated by releasing 3 HDRMs, once released the boom oscillates back and forth on a pair of pivots, similar to a restaurant kitchen door hinge, for around 120 seconds before coming to rest on 3 kinematic mounts which are used to provide an accurate reference location in the deployed position. Motion of the boom is damped through a combination of friction, spring hysteresis and flexing of the 120+ cables crossing the hinge. Considerable development work and accurate numerical modelling of the hinge motion was required to predict performance across a wide temperature range and ensure that during the 1st overshoot the boom did not damage itself, the harness or the spacecraft.Due to the magnetic cleanliness requirements of the spacecraft no magnetic materials could be used in the design of the hardware.

  20. The DNA of prophetic speech | de Wet | HTS Teologiese Studies ...

    African Journals Online (AJOL)

    The metaphorical images triggered by 'DNA' and 'genetic engineering' are deployed in illustrating the ambivalent position in which a prophetic preacher finds ... on the one hand, and disquiet about the possibility of forcing a human being against his or her will into meeting certain prescribed expectations on the other hand.

  1. Technology Deployment Annual Report 2014 December

    Energy Technology Data Exchange (ETDEWEB)

    Arterburn, George K. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2014-12-01

    This report is a summary of key Technology Deployment activities and achievements for 2014, including intellectual property, granted copyrights, royalties, license agreements, CRADAs, WFOs and Technology-Based Economic Development. Idaho National Laboratory (INL) is a Department of Energy (DOE) multi-program national laboratory that conducts research and development in all DOE mission areas. Like all other federal laboratories, INL has a statutory, technology transfer mission to make its capabilities and technologies available to all federal agencies, to state and local governments, and to universities and industry. To fulfill this mission, INL encourages its scientific, engineering, and technical staff to disclose new inventions and creations to ensure the resulting intellectual property is captured, protected, and made available to others who might benefit from it. As part of the mission, intellectual property is licensed to industrial partners for commercialization, creating jobs and delivering the benefits of federally funded technology to consumers. In other cases, unique capabilities are made available to other federal agencies or to regional small businesses to solve specific technical challenges. INL employees also work cooperatively with researchers and technical staff from the university and industrial sectors to further develop emerging technologies. In our multinational global economy, INL is contributing to the development of the next generation of engineers and scientists by licensing software to educational instiutitons throughout the world. This report is a catalog of selected INL technology transfer and commercialization transactions during this past year. The size and diversity of INL technical resources, coupled with the large number of relationships with other organizations, virtually ensures that a report of this nature will fail to capture all interactions. Recognizing this limitation, this report focuses on transactions that are specifically

  2. Tunable bandgaps in a deployable metamaterial

    Science.gov (United States)

    Nanda, Aditya; Karami, M. A.

    2018-06-01

    In this manuscript, we investigate deployable structures (such as solar arrays) and origami-inspired foldable structures as metamaterials capable of tunable wave manipulation. Specifically, we present a metamaterial whose bandgaps can be modulated by changing the fold angle of adjacent panels. The repeating unit cell of the structure consists of a beam (representing a panel) and a torsional spring (representing the folding mechanism). Two important cases are considered. Firstly, the fold angle (angle between adjacent beams), Ψ, is zero and only flexural waves propagate. In the second case, the fold angle is greater than zero (Ψ > 0). This causes longitudinal and transverse vibration to be coupled. FEM models are used to validate both these analyses. Increasing the fold angle was found to inflict notable changes to the wave transmission characteristics of the structure. In general, increasing the fold angles caused the bandwidth of bandgaps to increase. For the lowest four bandgaps we found bandwidth increases of 252 %, 177 %, 230 % and 163 % respectively at Ψ = 90 deg (relative to the bandwidths at Ψ = 0). In addition, non-trivial increases in bandwidth of the odd-numbered bandgaps occurs even at small fold angles-the bandwidth for the first and third bandgaps effectively double in size (increase by 100 %) at Ψ = 20 deg relative to those at Ψ = 0. This could have ramifications in the context of tunable wave manipulation and adaptive filtering. In addition, by expanding out the characteristic equation of transfer matrix for the straight structure, we prove that the upper band edge of the nth bandgap will always equal the nth simply supported natural frequency of the constituent beam. Further, we found that the ratio (EI/kt) is a pertinent parameter affecting the bandwidth of bandgaps. For low values of the ratio, effectively, no bandgap exists. For higher values of the ratio (EI/kt), we obtain a relatively large bandgap over which no waves propagate. This can

  3. Rapid identification of DNA-binding proteins by mass spectrometry

    DEFF Research Database (Denmark)

    Nordhoff, E.; Korgsdam, A.-M.; Jørgensen, H.F.

    1999-01-01

    We report a protocol for the rapid identification of DNA-binding proteins. Immobilized DNA probes harboring a specific sequence motif are incubated with cell or nuclear extract. Proteins are analyzed directly off the solid support by matrix-assisted laser desorption/ionization time-of-flight mass...... was validated by the identification of known prokaryotic and eukaryotic DNA-binding proteins, and its use provided evidence that poly(ADP-ribose) polymerase exhibits DNA sequence-specific binding to DNA....

  4. Analyzing policy support instruments and regulatory risk factors for wind energy deployment-A developers' perspective

    Energy Technology Data Exchange (ETDEWEB)

    Luethi, Sonja, E-mail: sonja.luethi@unisg.ch [University of St. Gallen, 9000 St. Gallen (Switzerland); Praessler, Thomas [Potsdam Institute for Climate Impact Research (Germany)

    2011-09-15

    A transition to a renewable energy system is high on the policy agenda in many countries. A promising energy source for a low-carbon energy future is wind. Policy-makers can attract wind energy development by providing attractive policy frameworks. This paper argues that apart from the level of financial support, both the risks stemming from the regulatory environment (legal security, administrative process and grid access) and the ability to finance projects play a critical role in determining the attractiveness of the development environment. It sheds light on how project developers trade off these different aspects and to what extent the attractiveness of a certain policy framework increases with the introduction of specific measures. Conjoint analysis is employed to provide empirical evidence on the preference of wind energy developers in the EU and the US. The analysis shows that developers' preferences are very similar across the studied regions and for different types of developers. Which policy measures could be most valuable depends on the specific existing environment. In some southeastern European countries, a reduction of administrative process duration may yield the highest utility gains, whereas, in the US, improvements in grid access regulation and an increase in remuneration levels may be more effective. - Highlights: > Paper suggests conjoint analysis as scenario tool for estimating potential effects of specific policy measures. > It provides a quantitative, empirical dataset of 119 onshore wind energy developers' preferences. > Results suggest that the aspects 'Legal security' and 'Remuneration' are important attributes. > Cluster analyses yields slightly different preferences for developers from EU and US.

  5. Human Parvovirus B19 Utilizes Cellular DNA Replication Machinery for Viral DNA Replication.

    Science.gov (United States)

    Zou, Wei; Wang, Zekun; Xiong, Min; Chen, Aaron Yun; Xu, Peng; Ganaie, Safder S; Badawi, Yomna; Kleiboeker, Steve; Nishimune, Hiroshi; Ye, Shui Qing; Qiu, Jianming

    2018-03-01

    Human parvovirus B19 (B19V) infection of human erythroid progenitor cells (EPCs) induces a DNA damage response and cell cycle arrest at late S phase, which facilitates viral DNA replication. However, it is not clear exactly which cellular factors are employed by this single-stranded DNA virus. Here, we used microarrays to systematically analyze the dynamic transcriptome of EPCs infected with B19V. We found that DNA metabolism, DNA replication, DNA repair, DNA damage response, cell cycle, and cell cycle arrest pathways were significantly regulated after B19V infection. Confocal microscopy analyses revealed that most cellular DNA replication proteins were recruited to the centers of viral DNA replication, but not the DNA repair DNA polymerases. Our results suggest that DNA replication polymerase δ and polymerase α are responsible for B19V DNA replication by knocking down its expression in EPCs. We further showed that although RPA32 is essential for B19V DNA replication and the phosphorylated forms of RPA32 colocalized with the replicating viral genomes, RPA32 phosphorylation was not necessary for B19V DNA replication. Thus, this report provides evidence that B19V uses the cellular DNA replication machinery for viral DNA replication. IMPORTANCE Human parvovirus B19 (B19V) infection can cause transient aplastic crisis, persistent viremia, and pure red cell aplasia. In fetuses, B19V infection can result in nonimmune hydrops fetalis and fetal death. These clinical manifestations of B19V infection are a direct outcome of the death of human erythroid progenitors that host B19V replication. B19V infection induces a DNA damage response that is important for cell cycle arrest at late S phase. Here, we analyzed dynamic changes in cellular gene expression and found that DNA metabolic processes are tightly regulated during B19V infection. Although genes involved in cellular DNA replication were downregulated overall, the cellular DNA replication machinery was tightly

  6. On-Demand Urine Analyzer

    Science.gov (United States)

    Farquharson, Stuart; Inscore, Frank; Shende, Chetan

    2010-01-01

    A lab-on-a-chip was developed that is capable of extracting biochemical indicators from urine samples and generating their surface-enhanced Raman spectra (SERS) so that the indicators can be quantified and identified. The development was motivated by the need to monitor and assess the effects of extended weightlessness, which include space motion sickness and loss of bone and muscle mass. The results may lead to developments of effective exercise programs and drug regimes that would maintain astronaut health. The analyzer containing the lab-on-a- chip includes materials to extract 3- methylhistidine (a muscle-loss indicator) and Risedronate (a bone-loss indicator) from the urine sample and detect them at the required concentrations using a Raman analyzer. The lab-on- a-chip has both an extractive material and a SERS-active material. The analyzer could be used to monitor the onset of diseases, such as osteoporosis.

  7. Device for analyzing a solution

    International Nuclear Information System (INIS)

    Marchand, Joseph.

    1978-01-01

    The device enables a solution containing an antigen to be analyzed by the radio-immunology technique without coming up against the problems of antigen-antibody complex and free antigen separation. This device, for analyzing a solution containing a biological compound capable of reacting with an antagonistic compound specific of the biological compound, features a tube closed at its bottom end and a component set and immobilized in the bottom of the tube so as to leave a capacity between the bottom of the tube and its lower end. The component has a large developed surface and is so shaped that it allows the solution to be analyzed to have access to the bottom of the tube; it is made of a material having some elastic deformation and able to take up a given quantity of the biological compound or of the antagonistic compound specific of the biological compound [fr

  8. Epigenetic Patterns of PTSD: DNA Methylation In Serum of OIF/OEF Servicemembers

    Science.gov (United States)

    2011-01-01

    also have no data on other relevant exposures which are known to affect DNA methylation , such as dietary factors ( folate , vitamin B12 intake), (54, 55...ANSI Std. Z39.18 W81XWH-08-2-0053 31 MAR 2008 - 31 DEC 2010Final01-01-2011 Epigenetic Patterns of PTSD: DNA Methylation in Serum of OIF/OEF...distribution unlimited PTSD, epigenetics, DNA methylation , cytokines, serum, pre-deployment, post-deployment Abstract on next page. 38 jrusiecki@usuhs.mil

  9. Multichannel analyzer embedded in FPGA

    International Nuclear Information System (INIS)

    Garcia D, A.; Hernandez D, V. M.; Vega C, H. R.; Ordaz G, O. O.; Bravo M, I.

    2017-10-01

    Ionizing radiation has different applications, so it is a very significant and useful tool, which in turn can be dangerous for living beings if they are exposed to uncontrolled doses. However, due to its characteristics, it cannot be perceived by any of the senses of the human being, so that in order to know the presence of it, radiation detectors and additional devices are required to quantify and classify it. A multichannel analyzer is responsible for separating the different pulse heights that are generated in the detectors, in a certain number of channels; according to the number of bits of the analog to digital converter. The objective of the work was to design and implement a multichannel analyzer and its associated virtual instrument, for nuclear spectrometry. The components of the multichannel analyzer were created in VHDL hardware description language and packaged in the Xilinx Vivado design suite, making use of resources such as the ARM processing core that the System on Chip Zynq contains and the virtual instrument was developed on the LabView programming graphics platform. The first phase was to design the hardware architecture to be embedded in the FPGA and for the internal control of the multichannel analyzer the application was generated for the ARM processor in C language. For the second phase, the virtual instrument was developed for the management, control and visualization of the results. The data obtained as a result of the development of the system were observed graphically in a histogram showing the spectrum measured. The design of the multichannel analyzer embedded in FPGA was tested with two different radiation detection systems (hyper-pure germanium and scintillation) which allowed determining that the spectra obtained are similar in comparison with the commercial multichannel analyzers. (Author)

  10. Loviisa nuclear power plant analyzer

    International Nuclear Information System (INIS)

    Porkholm, K.; Nurmilaukas, P.; Tiihonen, O.; Haenninen, M.; Puska, E.

    1992-12-01

    The APROS Simulation Environment has been developed since 1986 by Imatran Voima Oy (IVO) and the Technical Research Centre of Finland (VTT). It provides tools, solution algorithms and process components for use in different simulation systems for design, analysis and training purposes. One of its main nuclear applications is the Loviisa Nuclear Power Plant Analyzer (LPA). The Loviisa Plant Analyzer includes all the important plant components both in the primary and in the secondary circuits. In addition, all the main control systems, the protection system and the high voltage electrical systems are included. (orig.)

  11. Kismeth: Analyzer of plant methylation states through bisulfite sequencing

    Directory of Open Access Journals (Sweden)

    Martienssen Robert A

    2008-09-01

    Full Text Available Abstract Background There is great interest in probing the temporal and spatial patterns of cytosine methylation states in genomes of a variety of organisms. It is hoped that this will shed light on the biological roles of DNA methylation in the epigenetic control of gene expression. Bisulfite sequencing refers to the treatment of isolated DNA with sodium bisulfite to convert unmethylated cytosine to uracil, with PCR converting the uracil to thymidine followed by sequencing of the resultant DNA to detect DNA methylation. For the study of DNA methylation, plants provide an excellent model system, since they can tolerate major changes in their DNA methylation patterns and have long been studied for the effects of DNA methylation on transposons and epimutations. However, in contrast to the situation in animals, there aren't many tools that analyze bisulfite data in plants, which can exhibit methylation of cytosines in a variety of sequence contexts (CG, CHG, and CHH. Results Kismeth http://katahdin.mssm.edu/kismeth is a web-based tool for bisulfite sequencing analysis. Kismeth was designed to be used with plants, since it considers potential cytosine methylation in any sequence context (CG, CHG, and CHH. It provides a tool for the design of bisulfite primers as well as several tools for the analysis of the bisulfite sequencing results. Kismeth is not limited to data from plants, as it can be used with data from any species. Conclusion Kismeth simplifies bisulfite sequencing analysis. It is the only publicly available tool for the design of bisulfite primers for plants, and one of the few tools for the analysis of methylation patterns in plants. It facilitates analysis at both global and local scales, demonstrated in the examples cited in the text, allowing dissection of the genetic pathways involved in DNA methylation. Kismeth can also be used to study methylation states in different tissues and disease cells compared to a reference sequence.

  12. Deployment-based lifetime optimization model for homogeneous Wireless Sensor Network under retransmission.

    Science.gov (United States)

    Li, Ruiying; Liu, Xiaoxi; Xie, Wei; Huang, Ning

    2014-12-10

    Sensor-deployment-based lifetime optimization is one of the most effective methods used to prolong the lifetime of Wireless Sensor Network (WSN) by reducing the distance-sensitive energy consumption. In this paper, data retransmission, a major consumption factor that is usually neglected in the previous work, is considered. For a homogeneous WSN, monitoring a circular target area with a centered base station, a sensor deployment model based on regular hexagonal grids is analyzed. To maximize the WSN lifetime, optimization models for both uniform and non-uniform deployment schemes are proposed by constraining on coverage, connectivity and success transmission rate. Based on the data transmission analysis in a data gathering cycle, the WSN lifetime in the model can be obtained through quantifying the energy consumption at each sensor location. The results of case studies show that it is meaningful to consider data retransmission in the lifetime optimization. In particular, our investigations indicate that, with the same lifetime requirement, the number of sensors needed in a non-uniform topology is much less than that in a uniform one. Finally, compared with a random scheme, simulation results further verify the advantage of our deployment model.

  13. Large Scale eHealth Deployment in Europe: Insights from Concurrent Use of Standards.

    Science.gov (United States)

    Eichelberg, Marco; Chronaki, Catherine

    2016-01-01

    Large-scale eHealth deployment projects face a major challenge when called to select the right set of standards and tools to achieve sustainable interoperability in an ecosystem including both legacy systems and new systems reflecting technological trends and progress. There is not a single standard that would cover all needs of an eHealth project, and there is a multitude of overlapping and perhaps competing standards that can be employed to define document formats, terminology, communication protocols mirroring alternative technical approaches and schools of thought. eHealth projects need to respond to the important question of how alternative or inconsistently implemented standards and specifications can be used to ensure practical interoperability and long-term sustainability in large scale eHealth deployment. In the eStandards project, 19 European case studies reporting from R&D and large-scale eHealth deployment and policy projects were analyzed. Although this study is not exhaustive, reflecting on the concepts, standards, and tools for concurrent use and the successes, failures, and lessons learned, this paper offers practical insights on how eHealth deployment projects can make the most of the available eHealth standards and tools and how standards and profile developing organizations can serve the users embracing sustainability and technical innovation.

  14. Technological innovation in the energy sector: R and D, deployment, and learning-by-doing

    International Nuclear Information System (INIS)

    Sagar, Ambuj D.; Zwaan, Bob van der

    2006-01-01

    Technological innovation is fundamental for rendering the energy economy cleaner and more efficient with concomitant economic, developmental, and environmental benefits. This paper discusses aspects of R and D and 'learning-by-doing,' the main contributors to technological change that are complementary yet inter-linked. The relationship between the level of national energy R and D investments and changes in the trajectory of the country's energy system is complex; targeted efforts to promote deployment of new energy technologies play a major role in translating the results of R and D activities to changes in the energy system. Learning-by-doing is an important element of deployment, but it remains largely poorly understood. Hence this phenomenon needs to be 'unpacked' and its various aspects analyzed in detail, so as to allow better design of early deployment efforts to enhance learning gains. This paper highlights how public R and D and deployment efforts must work in tandem to expand the portfolio, and realize the potential, of new and improved energy technologies

  15. Method of Geometric Connected Disk Cover Problem for UAV realy network deployment

    Directory of Open Access Journals (Sweden)

    Chuang Liu

    2017-01-01

    Full Text Available Aiming at the problem of the effective connectivity of a large number of mobile combat units in the future aeronautic swarm operation, this paper proposes an idea of using UAV(Unmanned Aerial Vehicle to build, and studies the deployment of the network. User coverage and network connectivity are important for a relay network planning which are studied separately in traditional ways. In order to effectively combine these two factors while the network’s survivability is taken into account. Firstly, the concept of node aggregation degree is proposed. Secondly, a performance evaluation parameter for UAV relay network is proposed based on node aggregation degree, then analyzes the lack of deterministic deployment and presents one a PSO (VFA-PSO deployment algorithm based on virtual force. Finally, compared with the existing algorithms, the validity and stability of the algorithm are verified. The experimental results show that the VFA-PSO algorithm can effectively improve the network coverage and the survivability of the network under the premise of ensuring the network connectivity, and has better deployment effect.

  16. Deploying Renewables -- principles for effective policies

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-09-29

    Renewable energy can play a fundamental role in tackling climate change, environmental degradation and energy security. As these challenges have become ever more pressing, governments and markets are seeking innovative solutions. Yet, what are the key factors that will determine the success of renewable energy policies? How can current policies be improved to encourage greater deployment of renewables? What impact can more effective policies have on renewables' share in the future global energy mix and how soon? This publication addresses these questions. Responding to the Gleneagles G8 call for a clean and secure energy future, it highlights key policy tools to fast-track renewables into the mainstream. This analysis illustrates good practices by applying the combined metrics of effectiveness and efficiency to renewable energy policies in the electricity, heating and transport sectors. It highlights significant barriers to accelerating renewables penetration, and argues that the great potential of renewables can be exploited much more rapidly and to a much larger extent if good practices are adopted. Carefully designed policy frameworks, customised to support technologies at differing stages of maturity, will deliver a strong portfolio of renewable energy technologies. The document provides recommendations on key principles for policy design as a template for decision makers.

  17. Automating NEURON Simulation Deployment in Cloud Resources.

    Science.gov (United States)

    Stockton, David B; Santamaria, Fidel

    2017-01-01

    Simulations in neuroscience are performed on local servers or High Performance Computing (HPC) facilities. Recently, cloud computing has emerged as a potential computational platform for neuroscience simulation. In this paper we compare and contrast HPC and cloud resources for scientific computation, then report how we deployed NEURON, a widely used simulator of neuronal activity, in three clouds: Chameleon Cloud, a hybrid private academic cloud for cloud technology research based on the OpenStack software; Rackspace, a public commercial cloud, also based on OpenStack; and Amazon Elastic Cloud Computing, based on Amazon's proprietary software. We describe the manual procedures and how to automate cloud operations. We describe extending our simulation automation software called NeuroManager (Stockton and Santamaria, Frontiers in Neuroinformatics, 2015), so that the user is capable of recruiting private cloud, public cloud, HPC, and local servers simultaneously with a simple common interface. We conclude by performing several studies in which we examine speedup, efficiency, total session time, and cost for sets of simulations of a published NEURON model.

  18. Deployable structures using bistable reeled composites

    Science.gov (United States)

    Daton-Lovett, Andrew J.; Compton-Bishop, Quentin M.; Curry, Richard G.

    2000-06-01

    This paper describes an innovative, patented use of composite materials developed by RolaTube Technology Ltd. to make smart deployable structures. Bi-stable reeled composites (BRCs) can alternate between two stable forms; that of a strong, rigid structure and that of a compact coil of flat-wound material. Bi-stability arises as a result of the manipulation of Poisson's ratio and isotropy in the various layers of the material. BRCs are made of fiber- reinforced composite materials, most often with a thermoplastic matrix. A range of fibers and polymer matrices can be used according to the requirements of the operating environment. Samples of a BRC structure were constructed using layers of unidirectional, fiber-reinforced thermoplastic sheet with the layers at different angles. The whole assembly was then consolidated under conditions of elevated temperature and pressure. The properties of the BRC are described and the result of a series of experiments performed on the sample to determine the tensile strength of the BRC structure are reported. A full analysis using finite element methods is being undertaken in collaboration with the University of Cambridge, England. The first commercial use has been to fabricate boom and drive mechanisms for the remote inspection of industrial plant.

  19. Development, deployment and operations of ATLAS databases

    International Nuclear Information System (INIS)

    Vaniachine, A. V.; von der Schmitt, J. G.

    2008-01-01

    In preparation for ATLAS data taking, a coordinated shift from development towards operations has occurred in ATLAS database activities. In addition to development and commissioning activities in databases, ATLAS is active in the development and deployment (in collaboration with the WLCG 3D project) of the tools that allow the worldwide distribution and installation of databases and related datasets, as well as the actual operation of this system on ATLAS multi-grid infrastructure. We describe development and commissioning of major ATLAS database applications for online and offline. We present the first scalability test results and ramp-up schedule over the initial LHC years of operations towards the nominal year of ATLAS running, when the database storage volumes are expected to reach 6.1 TB for the Tag DB and 1.0 TB for the Conditions DB. ATLAS database applications require robust operational infrastructure for data replication between online and offline at Tier-0, and for the distribution of the offline data to Tier-1 and Tier-2 computing centers. We describe ATLAS experience with Oracle Streams and other technologies for coordinated replication of databases in the framework of the WLCG 3D services

  20. New technologies deployment for advanced power plants

    International Nuclear Information System (INIS)

    Kiyoshi, Yamauchi

    2007-01-01

    Mitsubishi Heavy Industries, Ltd. (MHI) has been the total engineering and manufacturing company of pressurized water reactors (PWRs) in Japan since the commencement of commercial operations of Mihama Unit 1 of the Kansai Electric Power Company in 1970. Over these decades, MHI has endeavored to develop a broad spread of nuclear technology, from design, manufacturing, and construction, to plant maintenance services. More recently, with the ever rising need for nuclear power generation around the world to prevent global warming and to cope with surging oil prices, MHI is striving to expand its nuclear power business in the world market, such as US-APWR (Advanced Pressurized Water Reactor) in the U.S., as well as to develop technology for advanced reactors and nuclear fuel cycles to ensure energy security in the future. This paper introduces these approaches, especially focused on new technologies deployment for the global needs, and clarifies the current status and future prospects of MHI as the world's leading nuclear company. (author)

  1. Deploying the advanced U.S. EPR

    International Nuclear Information System (INIS)

    Hagan, C.

    2007-01-01

    As electricity demand, clean air concerns and energy prices increase in the U.S., interest in new nuclear reactors is also on the rise. These factors - along with decades of outstanding performance of the nation's existing nuclear fleet - have contributed to a favorable market for new nuclear power in the U.S. Although no U.S. company has declared it actually will buy and build new reactors, many have actively expressed their interest through investment and regulatory interaction. The timing is also right for new reactors in terms of public perception, government policy and acceptance of the investment community. Amid this environment, the U.S. commercial power industry recently has begun pursuing new nuclear generation in earnest. AREVA, whose ongoing global market analyses indicated the need for additional baseload nuclear generation in the U.S., chose to license its EPR design to meet that need. This article will discuss the American market landscape for new nuclear and how AREVA is approaching it, present an overview of the company's U.S. EPR technology, and provide an update on the regulatory status of the design and deployment schedule. (orig.)

  2. The security analyzer: A security analyzer program written in Prolog

    International Nuclear Information System (INIS)

    Zimmerman, B.D.; Densley, P.J.

    1986-09-01

    The Security Analyzer is a software tool capable of analyzing the effectiveness of a facility's security system. It is written in the Prolog logic programming computer language, using entity-relationship data modeling techniques. The program performs the following functions: (1) provides descriptive, locational and operational status information about intrusion detectors and assessment devices (i.e., ''sensors'' and ''cameras'') upon request; (2) provides for storage and retrieval of maintenance history information for various components of the security system (including intrusion detectors), and allows for changing that information as desired; (3) provides a ''search'' mode, wherein all paths are found from any specified physical location to another specified location which satisfy user chosen ''intruder detection'' probability and elapsed time criteria (i.e., the program finds the ''weakest paths'' from a security point of view). The first two of these functions can be provided fairly easily with a conventional database program; the third function could be provided using Fortran or some similar language, though with substantial difficulty. In the Security Analyzer program, all these functions are provided in a simple and straight-forward manner. This simplicity is possible because the program is written in the symbolic (as opposed to numeric) processing language Prolog, and because the knowledge base is structured according to entity-relationship modeling principles. Also, the use of Prolog and the entity-relationship modeling technique allows the capabilities of the Security analyzer program, both for knowledge base interrogation and for searching-type operations, to be easily expanded in ways that would be very difficult for a numeric and more algorithmically deterministic language such as Fortran to duplicate. 4 refs

  3. Methods of analyzing crude oil

    Science.gov (United States)

    Cooks, Robert Graham; Jjunju, Fred Paul Mark; Li, Anyin; Rogan, Iman S.

    2017-08-15

    The invention generally relates to methods of analyzing crude oil. In certain embodiments, methods of the invention involve obtaining a crude oil sample, and subjecting the crude oil sample to mass spectrometry analysis. In certain embodiments, the method is performed without any sample pre-purification steps.

  4. Therapy Talk: Analyzing Therapeutic Discourse

    Science.gov (United States)

    Leahy, Margaret M.

    2004-01-01

    Therapeutic discourse is the talk-in-interaction that represents the social practice between clinician and client. This article invites speech-language pathologists to apply their knowledge of language to analyzing therapy talk and to learn how talking practices shape clinical roles and identities. A range of qualitative research approaches,…

  5. The Convertible Arbitrage Strategy Analyzed

    NARCIS (Netherlands)

    Loncarski, I.; Ter Horst, J.R.; Veld, C.H.

    2006-01-01

    This paper analyzes convertible bond arbitrage on the Canadian market for the period 1998 to 2004.Convertible bond arbitrage is the combination of a long position in convertible bonds and a short position in the underlying stocks. Convertible arbitrage has been one of the most successful strategies

  6. Analyzing the complexity of nanotechnology

    NARCIS (Netherlands)

    Vries, de M.J.; Schummer, J.; Baird, D.

    2006-01-01

    Nanotechnology is a highly complex technological development due to many uncertainties in our knowledge about it. The Dutch philosopher Herman Dooyeweerd has developed a conceptual framework that can be used (1) to analyze the complexity of technological developments and (2) to see how priorities

  7. Proton-beam energy analyzer

    International Nuclear Information System (INIS)

    Belan, V.N.; Bolotin, L.I.; Kiselev, V.A.; Linnik, A.F.; Uskov, V.V.

    1989-01-01

    The authors describe a magnetic analyzer for measurement of proton-beam energy in the range from 100 keV to 25 MeV. The beam is deflected in a uniform transverse magnetic field and is registered by photographing a scintillation screen. The energy spectrum of the beam is constructed by microphotometry of the photographic film

  8. DNA repair

    International Nuclear Information System (INIS)

    Van Zeeland, A.A.

    1984-01-01

    In this chapter a series of DNA repair pathways are discussed which are available to the cell to cope with the problem of DNA damaged by chemical or physical agents. In the case of microorganisms our knowledge about the precise mechanism of each DNA repair pathway and the regulation of it has been improved considerably when mutants deficient in these repair mechanisms became available. In the case of mammalian cells in culture, until recently there were very little repair deficient mutants available, because in almost all mammalian cells in culture at least the diploid number of chromosomes is present. Therefore the frequency of repair deficient mutants in such populations is very low. Nevertheless because replica plating techniques are improving some mutants from Chinese hamsters ovary cells and L5178Y mouse lymphoma cells are now available. In the case of human cells, cultures obtained from patients with certain genetic diseases are available. A number of cells appear to be sensitive to some chemical or physical mutagens. These include cells from patients suffering from xeroderma pigmentosum, Ataxia telangiectasia, Fanconi's anemia, Cockayne's syndrome. However, only in the case of xeroderma pigmentosum cells, has the sensitivity to ultraviolet light been clearly correlated with a deficiency in excision repair of pyrimidine dimers. Furthermore the work with strains obtained from biopsies from man is difficult because these cells generally have low cloning efficiencies and also have a limited lifespan in vitro. It is therefore very important that more repair deficient mutants will become available from established cell lines from human or animal origin

  9. Daddy's Days Away. A Deployment Activity Book for Parents & Children.

    Science.gov (United States)

    Marine Corps, Washington, DC.

    This booklet grew from an idea that the children of Marines might appreciate some special discussion of their family's separation during deployment. Information is provided for parents to help them express their feelings with their children about the deployment. Outlines of activities to do before leaving are included. Suggestions are given for…

  10. Hitting the ground running: Healthgrid deployment and adoption

    NARCIS (Netherlands)

    Gwadry-Sridhar, Femida; Olabarriaga, Silvia D.; van Kampen, Antoine; Bauer, Michael; Solomonides, Tony

    2010-01-01

    We consider the issues of healthgrid development, deployment and adoption in health care and research environments. While healthgrid technology could be deployed to support advanced medical research, we are not seeing its wide adoption. Understanding why this technology is not being exploited is one

  11. Accommodating Thickness in Origami-Based Deployable Arrays

    Science.gov (United States)

    Zirbel, Shannon A.; Magleby, Spencer P.; Howell, Larry L.; Lang, Robert J.; Thomson, Mark W.; Sigel, Deborah A.; Walkemeyer, Phillip E.; Trease, Brian P.

    2013-01-01

    The purpose of this work is to create deployment systems with a large ratio of stowed-to-deployed diameter. Deployment from a compact form to a final flat state can be achieved through origami-inspired folding of panels. There are many models capable of this motion when folded in a material with negligible thickness; however, when the application requires the folding of thick, rigid panels, attention must be paid to the effect of material thickness not only on the final folded state, but also during the folding motion (i.e., the panels must not be required to flex to attain the final folded form). The objective is to develop new methods for deployment from a compact folded form to a large circular array (or other final form). This paper describes a mathematical model for modifying the pattern to accommodate material thickness in the context of the design, modeling, and testing of a deployable system inspired by an origami six-sided flasher model. The model is demonstrated in hardware as a 1/20th scale prototype of a deployable solar array for space applications. The resulting prototype has a ratio of stowed-to-deployed diameter of 9.2 (or 1.25 m deployed outer diameter to 0.136 m stowed outer diameter).

  12. Post-deployment usability evaluation of a radiology workstation

    NARCIS (Netherlands)

    Jorritsma, Wiard; Cnossen, Fokie; Dierckx, Rudi; Oudkerk, Matthijs; van Ooijen, Peter

    2015-01-01

    Objective To evaluate the usability of a radiology workstation after deployment in a hospital. Significance In radiology, it is difficult to perform valid pre-deployment usability evaluations due to the heterogeneity of the user group, the complexity of the radiological workflow, and the complexity

  13. How Have Deployments During the War on Terrorism Affected Reenlistment?

    Science.gov (United States)

    2009-01-01

    Ethiopia, certain areas of Greece, Haiti, Indonesia, Iran, Iraq, Israel, Jordan, Kenya, Kosovo, Kuwait, Kyrgyzstan, Lebanon, Liberia, Malaysia ...deployment is a direct source of utility, as modeled in Chapter Three. Deployment is not simply another form of “work” that takes time away from “ leisure

  14. 50 CFR 635.21 - Gear operation and deployment restrictions.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 8 2010-10-01 2010-10-01 false Gear operation and deployment restrictions....21 Gear operation and deployment restrictions. Link to an amendment published at 75 FR 57701, Sept. 22, 2010. The green-stick gear authorization requirements under paragraphs (c)(2)(v)(A), (c)(2)(v)(B...

  15. Review of deployment technology for tethered satellite systems

    Science.gov (United States)

    Yu, B. S.; Wen, H.; Jin, D. P.

    2018-03-01

    Tethered satellite systems (TSSs) have attracted significant attention due to their potential and valuable applications for scientific research. With the development of various launched on-orbit missions, the deployment of tethers is considered a crucial technology for operation of a TSS. Both past orbiting experiments and numerical results have shown that oscillations of the deployed tether due to the Coriolis force and environmental perturbations are inevitable and that the impact between the space tether and end-body at the end of the deployment process leads to complicated nonlinear phenomena. Hence, a set of suitable control methods plays a fundamental role in tether deployment. This review article summarizes previous work on aspects of the dynamics, control, and ground-based experiments of tether deployment. The relevant basic principles, analytical expressions, simulation cases, and experimental results are presented as well.

  16. Deploying HEP applications using Xen and Globus Virtual Workspaces

    International Nuclear Information System (INIS)

    Agarwal, A; Desmarais, R; Gable, I; Grundy, D; P-Brown, D; Seuster, R; Vanderster, D C; Sobie, R; Charbonneau, A; Enge, R

    2008-01-01

    The deployment of HEP applications in heterogeneous grid environments can be challenging because many of the applications are dependent on specific OS versions and have a large number of complex software dependencies. Virtual machine monitors such as Xen could be used to package HEP applications, complete with their execution environments, to run on resources that do not meet their operating system requirements. Our previous work has shown HEP applications running within Xen suffer little or no performance penalty as a result of virtualization. However, a practical strategy is required for remotely deploying, booting, and controlling virtual machines on a remote cluster. One tool that promises to overcome the deployment hurdles using standard grid technology is the Globus Virtual Workspaces project. We describe strategies for the deployment of Xen virtual machines using Globus Virtual Workspace middleware that simplify the deployment of HEP applications

  17. Clinical Predictive Modeling Development and Deployment through FHIR Web Services.

    Science.gov (United States)

    Khalilia, Mohammed; Choi, Myung; Henderson, Amelia; Iyengar, Sneha; Braunstein, Mark; Sun, Jimeng

    2015-01-01

    Clinical predictive modeling involves two challenging tasks: model development and model deployment. In this paper we demonstrate a software architecture for developing and deploying clinical predictive models using web services via the Health Level 7 (HL7) Fast Healthcare Interoperability Resources (FHIR) standard. The services enable model development using electronic health records (EHRs) stored in OMOP CDM databases and model deployment for scoring individual patients through FHIR resources. The MIMIC2 ICU dataset and a synthetic outpatient dataset were transformed into OMOP CDM databases for predictive model development. The resulting predictive models are deployed as FHIR resources, which receive requests of patient information, perform prediction against the deployed predictive model and respond with prediction scores. To assess the practicality of this approach we evaluated the response and prediction time of the FHIR modeling web services. We found the system to be reasonably fast with one second total response time per patient prediction.

  18. Military deployment and reintegration: a systematic review of child coping.

    Science.gov (United States)

    Bello-Utu, Cindy F; DeSocio, Janiece E

    2015-02-01

    Child coping with parent military deployment and family reintegration. A systematic review of research literature was conducted to examine the effects of deployment and family reintegration on children in military families. A search of CINAHL, PubMed, Psyc-INFO, and SocINDEX databases was performed using the terms "military family," "military child," "child coping," "deployment," and "reintegration." The search was limited to publications between 2001 and 2014 to focus on the effects of Operation Enduring Freedom (OEF), Operation Iraqi Freedom (OIF), and Operation New Dawn (OND). Twenty-seven research reports met inclusion criteria. Three themes were extracted: A child's coping is influenced by (a) the child's age and development, (b) the mental health and coping of the non-deployed parent during deployment, and the mental health of both parents during family reintegration, and (c) the pre-existing resilience/vulnerability, cumulative risks, and resources of the child and family. © 2015 Wiley Periodicals, Inc.

  19. Shape memory alloy fracture as a deployment actuator

    International Nuclear Information System (INIS)

    Buban, Darrick M; Frantziskonis, George N

    2013-01-01

    The paper reports an experimental investigation into using shape memory alloy (SMA) as a deployment actuator. SMA specimens were heated and pulled to failure or pulled and heated to failure, thus developing an environmental and structural operating envelope for application as deployment mechanisms. The experimental results strongly suggest that SMAs can be implemented as deployment actuators. Recorded data shows that SMA fracture is possible over a wide range of temperatures and strains, filling a material performance gap not found in the literature. The obtained information allows design engineers to appropriately size SMAs given the design requirements for achieving the desired deployment effects. The major conclusion of the reported work is that SMAs as actuators are strong competitors to typical existing deployment efforts that use explosive or non-explosive actuators having implementation drawbacks such as the expense associated with special handling and the volume encountered in mounting the devices. (paper)

  20. Design of the De-Orbit Sail Boom Deployment Unit

    Science.gov (United States)

    Meyer, Sebastian; Hillebrandt, Martin; Straubel, Marco; Huhne, Christian

    2014-06-01

    The design of the De-Orbit Sail boom deployment unit is strongly driven by volume constraints, which are given by the cubesat container. Four CFRP (carbon fiber reinforced polymer) booms [4] with a cross-sectional shape of a double-omega and a length of 3.6 m are reeled on one spool in the center of the unit. The deployment of the four booms are controlled by an electric motor, which acts on the boom spool. Due to the volume limitation caused by the dimensions of the cubesat deployer the deployment unit has little room for the mechanisms components. With the aim to achieve a robust design, the deployment concept of the unit has greatly changed during the development process. The history of the design as well as the mechanisms are described. Additionally the results of the flight model testing are presented.

  1. An innovative deployable solar panel system for Cubesats

    Science.gov (United States)

    Santoni, Fabio; Piergentili, Fabrizio; Donati, Serena; Perelli, Massimo; Negri, Andrea; Marino, Michele

    2014-02-01

    One of the main Cubesat bus limitations is the available on-board power. The maximum power obtained using body mounted solar panels and advanced triple junction solar cells on a triple unit Cubesat is typically less than 10 W. The Cubesat performance and the mission scenario opened to these small satellite systems could be greatly enhanced by an increase of the available power. This paper describes the design and realization of a modular deployable solar panel system for Cubesats, consisting of a modular hinge and spring system that can be potentially used on-board single (1U), double(2U), triple (3U) and six units (6U) Cubesats. The size of each solar panels is the size of a lateral Cubesat surface. The system developed is the basis for a SADA (Solar Array Drive Assembly), in which a maneuvering capability is added to the deployed solar array in order to follow the apparent motion of the sun. The system design trade-off is discussed, comparing different deployment concepts and architectures, leading to the final selection for the modular design. A prototype of the system has been realized for a 3U Cubesat, consisting of two deployable solar panel systems, made of three solar panels each, for a total of six deployed solar panels. The deployment system is based on a plastic fiber wire and thermal cutters, guaranteeing a suitable level of reliability. A test-bed for the solar panel deployment testing has been developed, supporting the solar array during deployment reproducing the dynamical situation in orbit. The results of the deployment system testing are discussed, including the design and realization of the test-bed, the mechanical stress given to the solar cells by the deployment accelerations and the overall system performance. The maximum power delivered by the system is about 50.4 W BOL, greatly enhancing the present Cubesat solar array performance.

  2. Perceived effect of deployment on families of UK military personnel.

    Science.gov (United States)

    Thandi, G; Greenberg, N; Fear, N T; Jones, N

    2017-10-01

    In the UK, little is known about the perceived effects of deployment, on military families, from military personnel in theatre. To investigate military personnel's perceptions of the impact of deployment on intimate relationships and children. Deployed service personnel who were in a relationship, and who had children, completed a survey while deployed on combat operations. Data were taken from four mental health surveys carried out in Iraq in 2009 and Afghanistan in 2010, 2011 and 2014. Among 4265 participants, after adjusting for military and social-demographic covariates, perceiving that deployment had a negative impact on intimate relationships and children was associated with psychological distress, and traumatic stress symptoms. Military personnel who reported being in danger of being injured or killed during deployment, were more likely to report a perceived negative effect of deployment on their intimate relationships. Reservists were less likely to report a perceived negative impact of deployment on their children compared with regulars. Military personnel who themselves planned to separate from their partner were more likely to report psychological distress, and stressors at home. Perceived insufficient support from the Ministry of Defence was associated with poor mental health, and holding a junior rank. Deployed UK military personnel with symptoms of psychological distress, who experienced stressors at home, were especially likely to perceive that their family were inadequately supported by the military. Those planning to separate from their partner were at increased risk of suffering with mental health problems while deployed. © The Author 2017. Published by Oxford University Press on behalf of the Society of Occupational Medicine. All rights reserved. For Permissions, please email: journals.permissions@oup.com

  3. How and when 4. generation nuclear systems could deploy?

    International Nuclear Information System (INIS)

    Safa, H.; Bonin, B.

    2007-01-01

    Fast reactors exhibit two major advantages over classical thermal reactors: sustainability and waste minimization. The deployment of 4. generation nuclear reactors depends on economical, industrial and political issues. We feel that the waste radiotoxicity reduction argument, although very crucial and socially sensitive, could not by itself justify implementing a new reactor system including a dedicated reprocessing scheme. But the foreseen tension of the uranium market may urge on developing fast reactor systems. Putting aside politics, we tentatively try to answer a very simple question: At which uranium price will it be economically competitive to build a fast reactor instead of a light water one? The leveled cost of nuclear electricity is analyzed and split into its different components (investment, fuel supply, fuel cycle,..). Assuming some minimal and reasonable hypotheses, fast reactors costs are compared with light water ones. The uranium price necessary to compensate for the higher investment cost of fast reactors is then deduced. One major conclusion that can be drawn from our study may be summarized as follows: if the uranium market price maintains its present level for a long period of time, fast reactors are already today an economically attractive option. (authors)

  4. How and when 4. generation nuclear systems could deploy?

    Energy Technology Data Exchange (ETDEWEB)

    Safa, H.; Bonin, B. [CEA Saclay, Dir. de l' Energie Nucleaire, 91 - Gif sur Yvette (France)

    2007-07-01

    Fast reactors exhibit two major advantages over classical thermal reactors: sustainability and waste minimization. The deployment of 4. generation nuclear reactors depends on economical, industrial and political issues. We feel that the waste radiotoxicity reduction argument, although very crucial and socially sensitive, could not by itself justify implementing a new reactor system including a dedicated reprocessing scheme. But the foreseen tension of the uranium market may urge on developing fast reactor systems. Putting aside politics, we tentatively try to answer a very simple question: At which uranium price will it be economically competitive to build a fast reactor instead of a light water one? The leveled cost of nuclear electricity is analyzed and split into its different components (investment, fuel supply, fuel cycle,..). Assuming some minimal and reasonable hypotheses, fast reactors costs are compared with light water ones. The uranium price necessary to compensate for the higher investment cost of fast reactors is then deduced. One major conclusion that can be drawn from our study may be summarized as follows: if the uranium market price maintains its present level for a long period of time, fast reactors are already today an economically attractive option. (authors)

  5. Identifying barriers to aboriginal renewable energy deployment in Canada

    International Nuclear Information System (INIS)

    Krupa, Joel

    2012-01-01

    As one of the largest and wealthiest countries in the world, Canada stands well-positioned to take advantage of ongoing growth in North American demand for primary energy supply by expanding domestic delivery of renewable energy generation to internationally interconnected electric grids across the country. There are myriad benefits of adopting the renewable energy approach to development—as the province of Ontario has acknowledged through the implementation of their 2009 Green Energy Act—including drastic reductions in carbon emissions, the decommissioning of existing fossil fuel power generation that cause serious public health problems, and opportunities for sustainable development at the community level. One group in particular stands poised to shape these debates. In Canada, historically marginalized Aboriginal peoples remain one of the groups with the greatest potential for meeting these enormous renewable energy deployment needs. Aboriginal involvement in renewable energy generation in Canada has been as diverse as Canada's Aboriginal peoples and groups have already adopted a range of different solutions to meet energy supply needs. However, many significant barriers exist that prevent this diverse cultural group from reaching its full potential. The article identifies some of these shortcomings and analyzes their roots. - Highlights: ► Renewable energy is one of the most important sustainable development opportunities today. ► Aboriginal-led renewable development could dramatically increase Canadian supply. ► Surmountable barriers are identified.

  6. Mendel Meets CSI: Forensic Genotyping as a Method to Teach Genetics & DNA Science

    Science.gov (United States)

    Kurowski, Scotia; Reiss, Rebecca

    2007-01-01

    This article describes a forensic DNA science laboratory exercise for advanced high school and introductory college level biology courses. Students use a commercial genotyping kit and genetic analyzer or gene sequencer to analyze DNA recovered from a fictitious crime scene. DNA profiling and STR genotyping are outlined. DNA extraction, PCR, and…

  7. Analyzer for gamma cameras diagnostic

    International Nuclear Information System (INIS)

    Oramas Polo, I.; Osorio Deliz, J. F.; Diaz Garcia, A.

    2013-01-01

    This research work was carried out to develop an analyzer for gamma cameras diagnostic. It is composed of an electronic system that includes hardware and software capabilities, and operates from the acquisition of the 4 head position signals of a gamma camera detector. The result is the spectrum of the energy delivered by nuclear radiation coming from the camera detector head. This system includes analog processing of position signals from the camera, digitization and the subsequent processing of the energy signal in a multichannel analyzer, sending data to a computer via a standard USB port and processing of data in a personal computer to obtain the final histogram. The circuits are composed of an analog processing board and a universal kit with micro controller and programmable gate array. (Author)

  8. Methods for Analyzing Social Media

    DEFF Research Database (Denmark)

    Jensen, Jakob Linaa

    2013-01-01

    Social media is becoming increasingly attractive for users. It is a fast way to communicate ideas and a key source of information. It is therefore one of the most influential mediums of communication of our time and an important area for audience research. The growth of social media invites many...... new questions such as: How can we analyze social media? Can we use traditional audience research methods and apply them to online content? Which new research strategies have been developed? Which ethical research issues and controversies do we have to pay attention to? This book focuses on research...... strategies and methods for analyzing social media and will be of interest to researchers and practitioners using social media, as well as those wanting to keep up to date with the subject....

  9. New approach to analyzing vulnerability

    International Nuclear Information System (INIS)

    O'Callaghan, P.B.; Carlson, R.L.; Riedeman, G.W.

    1986-01-01

    The Westinghouse Hanford Company (WHC) has recently completed construction of the Fuel Cycle Plant (FCP) at Richland, Washington. At start-up the facility will fabricate driver fuel for the Fast Flux Test Facility in the Secure Automated Fabrication line. After construction completion, but before facility certification, the Department of Energy (DOE) Richland Operation Office requested that a vulnerability analysis be performed which assumed multiple insiders as a threat to the security system. A unique method of analyzing facility vulnerabilities was developed at the Security Applications Center (SAC), which is managed by WHC for DOE. The method that was developed verifies a previous vulnerability assessment, as well as introducing a modeling technique which analyzes security alarms in relation to delaying factors and possible insider activities. With this information it is possible to assess the relative strength or weakness of various possible routes to and from a target within a facility

  10. Technology Deployment Annual Report 2013 December

    Energy Technology Data Exchange (ETDEWEB)

    N/A

    2014-01-01

    available to the INL’s Office of Technology Deployment. However, the accomplishments cataloged in the report reflect the achievements and creativity of the researchers, technicians, support staff, and operators of the INL workforce.

  11. Analyzing the Facebook Friendship Graph

    OpenAIRE

    Catanese, Salvatore; De Meo, Pasquale; Ferrara, Emilio; Fiumara, Giacomo

    2010-01-01

    Online Social Networks (OSN) during last years acquired a huge and increasing popularity as one of the most important emerging Web phenomena, deeply modifying the behavior of users and contributing to build a solid substrate of connections and relationships among people using the Web. In this preliminary work paper, our purpose is to analyze Facebook, considering a significant sample of data reflecting relationships among subscribed users. Our goal is to extract, from this platform, relevant ...

  12. Use of Drosophila to study DNA repair

    International Nuclear Information System (INIS)

    Boyd, J.B.; Harris, P.V.; Sakaguchi, K.

    1988-01-01

    This paper discusses Drosophila, the premier metazoan organism for analyzing many fundamental features of eukaryotic gene regulation. The authors present adaptations of several approaches for studying DNA repair to an analysis of repair-defective mutants in Drosophila. A current understanding of Drosophila DNA repair is described

  13. Microarrays (DNA Chips) for the Classroom Laboratory

    Science.gov (United States)

    Barnard, Betsy; Sussman, Michael; BonDurant, Sandra Splinter; Nienhuis, James; Krysan, Patrick

    2006-01-01

    We have developed and optimized the necessary laboratory materials to make DNA microarray technology accessible to all high school students at a fraction of both cost and data size. The primary component is a DNA chip/array that students "print" by hand and then analyze using research tools that have been adapted for classroom use. The…

  14. Recurrence plot analysis of DNA sequences

    Energy Technology Data Exchange (ETDEWEB)

    Wu Zuobing [State Key Laboratory of Nonlinear Mechanics, Institute of Mechanics, Chinese Academy of Sciences, Beijing 100080 (China)]. E-mail: wuzb@lnm.imech.ac.cn

    2004-11-15

    Recurrence plot technique of DNA sequences is established on metric representation and employed to analyze correlation structure of nucleotide strings. It is found that, in the transference of nucleotide strings, a human DNA fragment has a major correlation distance, but a yeast chromosome's correlation distance has a constant increasing.

  15. Sulfur Dioxide Analyzer Instrument Handbook

    Energy Technology Data Exchange (ETDEWEB)

    Springston, Stephen R. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2016-05-01

    The Sulfur Dioxide Analyzer measures sulfur dioxide based on absorbance of UV light at one wavelength by SO2 molecules which then decay to a lower energy state by emitting UV light at a longer wavelength. Specifically, SO2 + hυ1 →SO2 *→SO2 + hυ2 The emitted light is proportional to the concentration of SO2 in the optical cell. External communication with the analyzer is available through an Ethernet port configured through the instrument network of the AOS systems. The Model 43i-TLE is part of the i-series of Thermo Scientific instruments. The i-series instruments are designed to interface with external computers through the proprietary Thermo Scientific iPort Software. However, this software is somewhat cumbersome and inflexible. Brookhaven National Laboratory (BNL) has written an interface program in National Instruments LabView that both controls the Model 43i-TLE Analyzer AND queries the unit for all measurement and housekeeping data. The LabView vi (the software program written by BNL) ingests all raw data from the instrument and outputs raw data files in a uniform data format similar to other instruments in the AOS and described more fully in Section 6.0 below.

  16. A new uranium automatic analyzer

    International Nuclear Information System (INIS)

    Xia Buyun; Zhu Yaokun; Wang Bin; Cong Peiyuan; Zhang Lan

    1993-01-01

    A new uranium automatic analyzer based on the flow injection analysis (FIA) principle has been developed. It consists of a multichannel peristaltic pump, an injection valve, a photometric detector, a single-chip microprocessor system and electronic circuit. The new designed multifunctional auto-injection valve can automatically change the injection volume of the sample and the channels so that the determination ranges and items can easily be changed. It also can make the instrument vary the FIA operation modes that it has functions of a universal instrument. A chromatographic column with extractant-containing resin was installed in the manifold of the analyzer for the concentration and separation of trace uranium. The 2-(5-bromo-2-pyridylazo)-5-diethyl-aminophenol (Br-PADAP) was used as colour reagent. Uranium was determined in the aqueous solution by adding cetyl-pyridium bromide (CPB). The uranium in the solution in the range 0.02-500 mg · L -1 can be directly determined without any pretreatment. A sample throughput rate of 30-90 h -1 and reproducibility of 1-2% were obtained. The analyzer has been satisfactorily applied to the laboratory and the plant

  17. Evaluation of Indoor Radio Deployment Options in High-Rise Building

    DEFF Research Database (Denmark)

    Nguyen, Huan Cong; Wigard, Jeroen; Kovacs, Istvan

    2017-01-01

    to the increase of inter-cell interference (ICI). Increasing transmit power brings largest gain when the density of indoor cell is low, and the noise and/or outdoor interference is the dominant source of performance degradation. When analyzing performance gain of an ideal receiver-side Interference Cancellation......In this paper we set out to analyze the indoor capacity under a realistic high-rise building scenario. The study takes into consideration the number of indoor cells deployed per floor, different inter-site distances (ISDs), transmit power settings and outdoor macro interference levels. The outcome...

  18. Analyzing Big Data in Psychology: A Split/Analyze/Meta-Analyze Approach

    Directory of Open Access Journals (Sweden)

    Mike W.-L. Cheung

    2016-05-01

    Full Text Available Big data is a field that has traditionally been dominated by disciplines such as computer science and business, where mainly data-driven analyses have been performed. Psychology, a discipline in which a strong emphasis is placed on behavioral theories and empirical research, has the potential to contribute greatly to the big data movement. However, one challenge to psychologists – and probably the most crucial one – is that most researchers may not have the necessary programming and computational skills to analyze big data. In this study we argue that psychologists can also conduct big data research and that, rather than trying to acquire new programming and computational skills, they should focus on their strengths, such as performing psychometric analyses and testing theories using multivariate analyses to explain phenomena. We propose a split/analyze/meta-analyze approach that allows psychologists to easily analyze big data. Two real datasets are used to demonstrate the proposed procedures in R. A new research agenda related to the analysis of big data in psychology is outlined at the end of the study.

  19. Analyzing Big Data in Psychology: A Split/Analyze/Meta-Analyze Approach.

    Science.gov (United States)

    Cheung, Mike W-L; Jak, Suzanne

    2016-01-01

    Big data is a field that has traditionally been dominated by disciplines such as computer science and business, where mainly data-driven analyses have been performed. Psychology, a discipline in which a strong emphasis is placed on behavioral theories and empirical research, has the potential to contribute greatly to the big data movement. However, one challenge to psychologists-and probably the most crucial one-is that most researchers may not have the necessary programming and computational skills to analyze big data. In this study we argue that psychologists can also conduct big data research and that, rather than trying to acquire new programming and computational skills, they should focus on their strengths, such as performing psychometric analyses and testing theories using multivariate analyses to explain phenomena. We propose a split/analyze/meta-analyze approach that allows psychologists to easily analyze big data. Two real datasets are used to demonstrate the proposed procedures in R. A new research agenda related to the analysis of big data in psychology is outlined at the end of the study.

  20. DNA-mediated self-assembly of carbon nanotubes on gold

    International Nuclear Information System (INIS)

    Sanchez-Pomales, Germarie; Rivera-Velez, Nelson E; Cabrera, Carlos R

    2007-01-01

    This report presents the use of disulfide-modified single-stranded DNA (ssDNA) to form DNA self-assembled monolayers (SAMs) and mixed DNA-carbon nanotube (CNT) hybrids SAMs on gold substrates. Mixed DNA-CNT SAMs are composed of DNA, mercaptohexanol (MCH) and DNA-CNT aggregates. Both, DNA-CNT and DNA areas of the mixed SAMs were analyzed and compared to traditional DNA SAMs. The results suggest the formation of a more compact and densely packed monolayer of DNA-CNT in comparison with DNA. The use of DNA-CNT hybrids to form SAMs on gold substrates might represent a new approach to improve the immobilization of DNA strands on gold, and might therefore help with the development of enhanced DNA sensors

  1. Implications of Deployed and Nondeployed Fathers on Seventh Graders' California Achievement Test Scores during a Military Crisis.

    Science.gov (United States)

    Pisano, Mark C.

    The differences in California Achievement Test (CAT) scores from 1990 to 1991 in seventh graders, currently enrolled in Albritton Junior High School in the Fort Bragg Schools, of deployed and nondeployed fathers were analyzed. CAT percentile scores from 1990 and 1991 (1991 being the year of "Desert Storm") were obtained in reading, math…

  2. The security analyzer, a security analyzer program written in Prolog

    International Nuclear Information System (INIS)

    Zimmerman, B.D.; Densley, P.J.; Carlson, R.L.

    1987-01-01

    A technique has been developed to characterize a nuclear facility and measure the strengths and weaknesses of the physical protection system. It utilizes the artificial intelligence capabilities available in the prolog programming language to probe a facility's defenses and find potential attack paths that meet designated search criteria. As sensors or barriers become inactive due to maintenance, failure, or inclement weather conditions, the protection system can rapidly be reanalyzed to discover weaknesses that would need to be strengthened by alternative means. Conversely, proposed upgrades and enhancements can be easily entered into the database and their effect measured against a variety of potential adversary attacks. Thus the security analyzer is a tool that aids the protection planner as well as the protection operations staff

  3. Human mitochondrial DNA (mtDNA) types in Malaysia

    International Nuclear Information System (INIS)

    Lian, L.H.; Koh, C.L.; Lim, M.E.

    2000-01-01

    Each human cell contains hundreds of mitochondria and thousands of double-stranded circular mtDNA. The delineation of human mtDNA variation and genetics over the past decade has provided unique and often startling insights into human evolution, degenerative diseases, and aging. Each mtDNA of 16,569 base pairs, encodes 13 polypeptides essential to the enzymes of the mitochondrial energy generating pathway, plus the necessary tRNAs and rRNAs. The highly polymorphic noncoding D-(displacement) loop region, also called the control region, is approximately 1.2 kb long. It contains two well-characterized hypervariable (HV-) regions, HV1 and HV2. MtDNA identification is usually based on these sequence differences. According to the TWTGDAM (Technical Working Group for DNA Analysis Methods), the minimum requirement for a mtDNA database for HV1 is from positions 16024 to 16365 and for HV2, from positions 00073 to 00340. The targeted Malaysian population subgroups for this study were mainly the Malays, Chinese, Indians, and indigenous Ibans, Bidayuhs, Kadazan-Dusuns, and Bajaus. Research methodologies undertaken included DNA extraction of samples from unrelated individuals, amplification of the specific regions via the polymerase chain reaction (PCR), and preparation of template DNA for sequencing by using an automated DNA sequencer. Sufficient nucleotide sequence data were generated from the mtDNA analysis. When the sequences were analyzed, sequence variations were found to be caused by nucleotide substitutions, insertions, and deletions. Of the three causes of the sequence variations, nucleotide substitutions (86.1%) accounted for the vast majority of polymorphism. It is noted that transitions (83.5%) were predominant when compared to the significantly lower frequencies of transversions (2.6%). Insertions (0.9%) and deletions (13.0%) were rather rare and found only in HV2. The data generated will also form the basis of a Malaysian DNA sequence database of mtDNA D

  4. The Aqueduct Global Flood Analyzer

    Science.gov (United States)

    Iceland, Charles

    2015-04-01

    As population growth and economic growth take place, and as climate change accelerates, many regions across the globe are finding themselves increasingly vulnerable to flooding. A recent OECD study of the exposure of the world's large port cities to coastal flooding found that 40 million people were exposed to a 1 in 100 year coastal flood event in 2005, and the total value of exposed assets was about US 3,000 billion, or 5% of global GDP. By the 2070s, those numbers were estimated to increase to 150 million people and US 35,000 billion, or roughly 9% of projected global GDP. Impoverished people in developing countries are particularly at risk because they often live in flood-prone areas and lack the resources to respond. WRI and its Dutch partners - Deltares, IVM-VU University Amsterdam, Utrecht University, and PBL Netherlands Environmental Assessment Agency - are in the initial stages of developing a robust set of river flood and coastal storm surge risk measures that show the extent of flooding under a variety of scenarios (both current and future), together with the projected human and economic impacts of these flood scenarios. These flood risk data and information will be accessible via an online, easy-to-use Aqueduct Global Flood Analyzer. We will also investigate the viability, benefits, and costs of a wide array of flood risk reduction measures that could be implemented in a variety of geographic and socio-economic settings. Together, the activities we propose have the potential for saving hundreds of thousands of lives and strengthening the resiliency and security of many millions more, especially those who are most vulnerable. Mr. Iceland will present Version 1.0 of the Aqueduct Global Flood Analyzer and provide a preview of additional elements of the Analyzer to be released in the coming years.

  5. Fuel analyzer; Analisador de combustiveis

    Energy Technology Data Exchange (ETDEWEB)

    Cozzolino, Roberval [RS Motors, Indaiatuba, SP (Brazil)

    2008-07-01

    The current technology 'COMBUSTIMETRO' aims to examine the fuel through performance of the engine, as the role of the fuel is to produce energy for the combustion engine in the form of which is directly proportional to the quality and type of fuel. The 'COMBUSTIMETRO' has an engine that always keeps the same entry of air, fuel and fixed point of ignition. His operation is monitored by sensors (Sonda Lambda, RPM and Gases Analyzer) connected to a processor that performs calculations and records the information, generate reports and graphs. (author)

  6. Home front: post-deployment mental health and divorces.

    Science.gov (United States)

    Negrusa, Brighita; Negrusa, Sebastian

    2014-06-01

    Since 2003, about 14 % of U.S. Army soldiers have reported symptoms of posttraumatic stress disorder (PTSD) following deployments. In this article, we examine how post-deployment symptoms of PTSD and of other mental health conditions are related to the probability of divorce among married active-duty U.S. Army soldiers. For this purpose, we combine Army administrative individual-level longitudinal data on soldiers' deployments, marital history, and sociodemographic characteristics with their self-reported post-deployment health information. Our estimates indicate that time spent in deployment increases the divorce risk among Army enlisted personnel and that PTSD symptoms are associated with further increases in the odds of divorce. Although officers are generally less likely to screen positive for PTSD than enlisted personnel, we find a stronger relationship between PTSD symptoms and divorces among Army officers who are PTSD-symptomatic than among enlisted personnel. We estimate a larger impact of deployments on the divorce risk among female soldiers, but we do not find a differential impact of PTSD symptoms by gender. Also, we find that most of the effect of PTSD symptoms occurs early in the career of soldiers who deploy multiple times.

  7. Analysis of performance and device parameters of CIGS PV modules deployed outdoors

    Energy Technology Data Exchange (ETDEWEB)

    Radue, C. [Physics Department, P.O. Box 77000, Nelson Mandela Metropolitan University, Port Elizabeth, 6031 (South Africa)], E-mail: chantelle.radue@nmmu.ac.za; Dyk, E.E. van; Macabebe, E.Q. [Physics Department, P.O. Box 77000, Nelson Mandela Metropolitan University, Port Elizabeth, 6031 (South Africa)

    2009-02-02

    Two 20 W copper indium gallium diselenide photovoltaic modules were subjected to a thorough indoor assessment procedure, followed by outdoor deployment at the Nelson Mandela Metropolitan University as part of an ongoing study. The initial indoor measurement of maximum power output (P{sub MAX}) of one of the modules was considerably higher than the manufacturer's rating (E.E. van Dyk, C. Radue and A.R. Gxasheka, Thin Solid Films 515 (2007) 6196). The modules were deployed on a dual-axis solar tracker and current-voltage characteristics were obtained weekly. In addition to the normal PV parameters of short-circuit current, open-circuit voltage, P{sub MAX}, fill factor and efficiency, shunt and series resistances were also monitored. The performances of the two modules are compared and analyzed and the results presented in this paper.

  8. Analysis of performance and device parameters of CIGS PV modules deployed outdoors

    International Nuclear Information System (INIS)

    Radue, C.; Dyk, E.E. van; Macabebe, E.Q.

    2009-01-01

    Two 20 W copper indium gallium diselenide photovoltaic modules were subjected to a thorough indoor assessment procedure, followed by outdoor deployment at the Nelson Mandela Metropolitan University as part of an ongoing study. The initial indoor measurement of maximum power output (P MAX ) of one of the modules was considerably higher than the manufacturer's rating (E.E. van Dyk, C. Radue and A.R. Gxasheka, Thin Solid Films 515 (2007) 6196). The modules were deployed on a dual-axis solar tracker and current-voltage characteristics were obtained weekly. In addition to the normal PV parameters of short-circuit current, open-circuit voltage, P MAX , fill factor and efficiency, shunt and series resistances were also monitored. The performances of the two modules are compared and analyzed and the results presented in this paper

  9. Impact of Federal Tax Policy on Utility-Scale Solar Deployment Given Financing Interactions

    Energy Technology Data Exchange (ETDEWEB)

    Mai, Trieu; Cole, Wesley; Krishnan, Venkat; Bolinger, Mark

    2015-09-28

    In this study, the authors conducted a literature review of approaches and assumptions used by other modeling teams and consultants with respect to solar project financing; developed and incorporated an ability to model the likely financing shift away from more expensive sources of capital and toward cheaper sources as the investment tax credit declines in the ReEDS model; and used the 'before and after' versions of the ReEDS model to isolate and analyze the deployment impact of the financing shift under a range of conditions. Using ReEDS scenarios with this improved capability, we find that this 'financing' shift would soften the blow of the ITC reversion; however, the overall impacts of such a shift in capital structure are estimated to be small and near-term utility-scale PV deployment is found to be much more sensitive to other factors that might drive down utility-scale PV prices.

  10. Evaluating Solar Resource Data Obtained from Multiple Radiometers Deployed at the National Renewable Energy Laboratory: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Habte, A.; Sengupta, M.; Andreas, A.; Wilcox, S.; Stoffel, T.

    2014-09-01

    Solar radiation resource measurements from radiometers are used to predict and evaluate the performance of photovoltaic and concentrating solar power systems, validate satellite-based models for estimating solar resources, and advance research in solar forecasting and climate change. This study analyzes the performance of various commercially available radiometers used for measuring global horizontal irradiances (GHI) and direct normal irradiances (DNI). These include pyranometers, pyrheliometers, rotating shadowband irradiometers, and a pyranometer with a shading ring deployed at the National Renewable Energy Laboratory's Solar Radiation Research Laboratory (SRRL). The radiometers in this study were deployed for one year (from April 1, 2011, through March 31, 2012) and compared to measurements from radiometers with the lowest values of estimated measurement uncertainties for producing reference GHI and DNI.

  11. Discursive Deployments: Mobilizing Support for Municipal and Community Wireless Networks in the U.S.

    Energy Technology Data Exchange (ETDEWEB)

    Alvarez, Rosio; Rodriguez, Juana Maria

    2008-08-16

    This paper examines Municipal Wireless (MW) deployments in the United States. In particular, the interest is in understanding how discourse has worked to mobilize widespread support for MW networks. We explore how local governments discursively deploy the language of social movements to create a shared understanding of the networking needs of communities. Through the process of"framing" local governments assign meaning to the MW networks in ways intended to mobilize support anddemobilize opposition. The mobilizing potential of a frame varies and is dependent on its centrality and cultural resonance. We examine the framing efforts of MW networks by using a sample of Request for Proposals for community wireless networks, semi-structured interviews and local media sources. Prominent values that are central to a majority of the projects and others that are culturally specific are identified and analyzed for their mobilizing potency.

  12. Organizational Capability Deployment Analysis for Technology Conversion into Processes, Products and Services

    Directory of Open Access Journals (Sweden)

    Tomoe Daniela Hamanaka Gusberti

    2013-12-01

    Full Text Available This article discusses Organizational Capabilities as the basic components of business models that emerged under the New Product Development Process and Technological Management. In the context of the new Technology Based Companies Development, it adopts a qualitative research in order to identify, analyze and underpin the organizational capability deployment in a process of technology conversion into product and service. The analysis was carried out considering concepts from literature review, in a technology based enterprise started by an academic spin-off company. The analysis enabled the elicitation of a Business Model and the discussion of their components, and correspondent evolution hypothesis. The paper provides an example of capability deployment accordingly the established theory illustrated by a case study. The study not just enumerate the needed partners, resources, customer channels, it enabled the description of their connection, representing the logic behind the decision made to develop the conceptual model. This detailed representation of the model allows better addressed discussions.

  13. Computational applications of DNA physical scales

    DEFF Research Database (Denmark)

    Baldi, Pierre; Chauvin, Yves; Brunak, Søren

    1998-01-01

    that these scales provide an alternative or complementary compact representation of DNA sequences. As an example we construct a strand invariant representation of DNA sequences. The scales can also be used to analyze and discover new DNA structural patterns, especially in combinations with hidden Markov models......The authors study from a computational standpoint several different physical scales associated with structural features of DNA sequences, including dinucleotide scales such as base stacking energy and propellor twist, and trinucleotide scales such as bendability and nucleosome positioning. We show...

  14. Computational applications of DNA structural scales

    DEFF Research Database (Denmark)

    Baldi, P.; Chauvin, Y.; Brunak, Søren

    1998-01-01

    that these scales provide an alternative or complementary compact representation of DNA sequences. As an example, we construct a strand-invariant representation of DNA sequences. The scales can also be used to analyze and discover new DNA structural patterns, especially in combination with hidden Markov models......Studies several different physical scales associated with the structural features of DNA sequences from a computational standpoint, including dinucleotide scales, such as base stacking energy and propeller twist, and trinucleotide scales, such as bendability and nucleosome positioning. We show...

  15. Pneumothorax, without chest wall fracture, following airbag deployment

    Directory of Open Access Journals (Sweden)

    Samuel Parsons

    2010-12-01

    Full Text Available Air bags are an automatic crash protection system. They have been shown to reduce mortality from motor vehicle accidents by 31% following direct head-on impacts, by 19% following any frontal impact and by 11% overall. Despite obvious benefits there has been a corresponding increase in the number of injuries resulting from their deployment. We describe a case of a pneumothorax in the absence of chest wall pathology associated with airbag deployment, in a belted driver. There has been one previous description of pneumothorax associated with airbag deployment, in an unbelted driver.

  16. Evaluation of Radiometers Deployed at the National Renewable Energy Laboratory's Solar Radiation Research Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Habte, Aron; Wilcox, Stephen; Stoffel, Thomas

    2015-12-23

    This study analyzes the performance of various commercially available radiometers used for measuring global horizontal irradiances and direct normal irradiances. These include pyranometers, pyrheliometers, rotating shadowband radiometers, and a pyranometer with fixed internal shading and are all deployed at the National Renewable Energy Laboratory's Solar Radiation Research Laboratory. Data from 32 global horizontal irradiance and 19 direct normal irradiance radiometers are presented. The radiometers in this study were deployed for one year (from April 1, 2011, through March 31, 2012) and compared to measurements from radiometers with the lowest values of estimated measurement uncertainties for producing reference global horizontal irradiances and direct normal irradiances.

  17. Compact Microwave Fourier Spectrum Analyzer

    Science.gov (United States)

    Savchenkov, Anatoliy; Matsko, Andrey; Strekalov, Dmitry

    2009-01-01

    A compact photonic microwave Fourier spectrum analyzer [a Fourier-transform microwave spectrometer, (FTMWS)] with no moving parts has been proposed for use in remote sensing of weak, natural microwave emissions from the surfaces and atmospheres of planets to enable remote analysis and determination of chemical composition and abundances of critical molecular constituents in space. The instrument is based on a Bessel beam (light modes with non-zero angular momenta) fiber-optic elements. It features low power consumption, low mass, and high resolution, without a need for any cryogenics, beyond what is achievable by the current state-of-the-art in space instruments. The instrument can also be used in a wide-band scatterometer mode in active radar systems.

  18. DNA Repair Systems

    Indian Academy of Sciences (India)

    DNA molecule which makes it ideal for storage and propagation of genetic information. ... of these errors are broadly referred to as DNA repair. DNA can ... changes occur in the human genome per day. ..... nails, frequent physical and mental.

  19. Climate Model Diagnostic Analyzer Web Service System

    Science.gov (United States)

    Lee, S.; Pan, L.; Zhai, C.; Tang, B.; Jiang, J. H.

    2014-12-01

    We have developed a cloud-enabled web-service system that empowers physics-based, multi-variable model performance evaluations and diagnoses through the comprehensive and synergistic use of multiple observational data, reanalysis data, and model outputs. We have developed a methodology to transform an existing science application code into a web service using a Python wrapper interface and Python web service frameworks. The web-service system, called Climate Model Diagnostic Analyzer (CMDA), currently supports (1) all the observational datasets from Obs4MIPs and a few ocean datasets from NOAA and Argo, which can serve as observation-based reference data for model evaluation, (2) many of CMIP5 model outputs covering a broad range of atmosphere, ocean, and land variables from the CMIP5 specific historical runs and AMIP runs, and (3) ECMWF reanalysis outputs for several environmental variables in order to supplement observational datasets. Analysis capabilities currently supported by CMDA are (1) the calculation of annual and seasonal means of physical variables, (2) the calculation of time evolution of the means in any specified geographical region, (3) the calculation of correlation between two variables, (4) the calculation of difference between two variables, and (5) the conditional sampling of one physical variable with respect to another variable. A web user interface is chosen for CMDA because it not only lowers the learning curve and removes the adoption barrier of the tool but also enables instantaneous use, avoiding the hassle of local software installation and environment incompatibility. CMDA will be used as an educational tool for the summer school organized by JPL's Center for Climate Science in 2014. In order to support 30+ simultaneous users during the school, we have deployed CMDA to the Amazon cloud environment. The cloud-enabled CMDA will provide each student with a virtual machine while the user interaction with the system will remain the same

  20. Synthesis of DNA

    Science.gov (United States)

    Mariella, Jr., Raymond P.

    2008-11-18

    A method of synthesizing a desired double-stranded DNA of a predetermined length and of a predetermined sequence. Preselected sequence segments that will complete the desired double-stranded DNA are determined. Preselected segment sequences of DNA that will be used to complete the desired double-stranded DNA are provided. The preselected segment sequences of DNA are assembled to produce the desired double-stranded DNA.

  1. The Intertwined Roles of DNA Damage and Transcription

    OpenAIRE

    Di Palo, Giacomo

    2016-01-01

    DNA damage and transcription are two interconnected events. Transcription can induce damage and scheduled DNA damage can be required for transcription. Here, we analyzed genome-wide distribution of 8oxodG-marked oxidative DNA damage obtained by OxiDIP-Seq, and we found a correlation with transcription of protein coding genes.

  2. Water Quality Vocabulary Development and Deployment

    Science.gov (United States)

    Simons, B. A.; Yu, J.; Cox, S. J.

    2013-12-01

    Semantic descriptions of observed properties and associated units of measure are fundamental to understanding of environmental observations, including groundwater, surface water and marine water quality. Semantic descriptions can be captured in machine-readable ontologies and vocabularies, thus providing support for the annotation of observation values from the disparate data sources with appropriate and accurate metadata, which is critical for achieving semantic interoperability. However, current stand-alone water quality vocabularies provide limited support for cross-system comparisons or data fusion. To enhance semantic interoperability, the alignment of water-quality properties with definitions of chemical entities and units of measure in existing widely-used vocabularies is required. Modern ontologies and vocabularies are expressed, organized and deployed using Semantic Web technologies. We developed an ontology for observed properties (i.e. a model for expressing appropriate controlled vocabularies) which extends the NASA/TopQuadrant QUDT ontology for Unit and QuantityKind with two additional classes and two properties (see accompanying paper by Cox, Simons and Yu). We use our ontology to populate the Water Quality vocabulary with a set of individuals of each of the four key classes (and their subclasses), and add appropriate relationships between these individuals. This ontology is aligned with other relevant stand-alone Water Quality vocabularies and domain ontologies. Developing the Water Quality vocabulary involved two main steps. First, the Water Quality vocabulary was populated with individuals of the ObservedProperty class, which was determined from a census of existing datasets and services. Each ObservedProperty individual relates to other individuals of Unit and QuantityKind (taken from QUDT where possible), and to IdentifiedObject individuals. As a large fraction of observed water quality data are classified by the chemical substance involved, the

  3. Patriot PAC-2 Development and Deployment in The Gulf War

    National Research Council Canada - National Science Library

    Sherman, J

    2003-01-01

    .... Patriot PAC-2 is a case study in effective project management that resulted in the extraordinary acceleration in the final stages of development production and deployment in time to play a historic role in the Gulf War...

  4. New Analysis and Theory of Deployable Folded Structures, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — A recently developed mathematical theory has great value for deployable space structures and in situ manufacture of large beams, panels, cylinders and other...

  5. New Analysis and Theory of Deployable Folded Structures, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — A recently developed mathematical folding theory has great value for deployable space structures and in situ manufacture of large beams, panels and cylinders. The...

  6. Costs and benefits of MDOT intelligent transportation system deployments.

    Science.gov (United States)

    2015-07-01

    This report analyses costs and benefits of Intelligent Transportation Systems (ITS) deployed by : the Michigan Department of Transportation (MDOT). MDOT ITS focuses on traffic incident : management and also provide Freeway Courtesy Patrol services. A...

  7. Design and Deployment of Mobile FSO Communication System

    KAUST Repository

    Alheadary, Wael Ghazy

    2017-05-08

    As a potential solution to many applications, we developed a mobile free-space optical (FSO) system that achieves 1Gbps with transmission distance of 70 m. This system needs minimal preparation to be deployed within an hour.

  8. Effects of Deployments on Homestation Job Stress and Burnout

    National Research Council Canada - National Science Library

    Johnson, S. R

    2005-01-01

    .... The increased rate of deployments, coupled with the reduction in resources, has military leaders concerned that these changing demands will cause undue strain, adversely affecting the military member's quality of life...

  9. Morphing structures using soft polymers for active deployment

    International Nuclear Information System (INIS)

    Daynes, Stephen; Grisdale, Amy; Trask, Richard; Seddon, Annela

    2014-01-01

    In this study, we take inspiration from morphing strategies observed in nature, origami design and stiffness tailoring principles in engineering, to develop a thin walled, low cost, bistable cell geometry capable of reversibly unfolding from a flat configuration to a highly textured configuration. Finite element analysis was used to model the cell deployment and capture the experimentally observed bistability of the reinforced silicone elastomer. Through the combination of flexible elastomers with locally reinforced regions enables a highly tailorable and controllable deployment response. These cells are bistable allowing them to maintain their shape when either deployed or retracted without sustained actuation. It is proposed that such deployable cells with reversible surfaces and texture change can be used as a means of adaptive camouflage. (fast track communication)

  10. EOP CRITTERCAM Deployments on French Frigate Shoals monk seals

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — CRITTERCAMs, were deployed on a 42 monk seals at French Frigate Shoals Hawaii. Sixty nine hours of video comprised of 3192 recording segments collected at...

  11. Creating a Comprehensive Solar Water Heating Deployment Strategy

    Energy Technology Data Exchange (ETDEWEB)

    Focus Marketing Services

    1999-08-18

    This report details the results of a research conducted in 1998 and 1999 and outlines a marketing deployment plan designed for businesses interested in marketing solar water heaters in the new home industry.

  12. Creating a Comprehensive Solar Water Heating Deployment Strategy

    International Nuclear Information System (INIS)

    Focus Marketing Services

    1999-01-01

    This report details the results of a research conducted in 1998 and 1999 and outlines a marketing deployment plan designed for businesses interested in marketing solar water heaters in the new home industry

  13. Flexible, Phase Change Fabric for Deployable Decelerators, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — SDMA proposes to develop a flexible fabric containing Phase Change Materials that is suitable for use on Deployable Decelerators. This technology will make...

  14. The feasibility of Quality Function Deployment (QFD) as an ...

    African Journals Online (AJOL)

    The feasibility of Quality Function Deployment (QFD) as an assessment and quality ... and facilities that had the most pertinent information on the research focus. ... Keywords: Customer Satisfaction Performance; Graduate School; Quality ...

  15. The American Satellite Company (ASC) satellite deployed from payload bay

    Science.gov (United States)

    1985-01-01

    The American Satellite Company (ASC) communications satellite is deployed from the payload bay of the Shuttle Discovery. A portion of the cloudy surface of the earth can be seen to the left of the frame.

  16. Accelerating the deployment of offshore renewable energy technologies. Final Report

    Energy Technology Data Exchange (ETDEWEB)

    MacDonald, Mott

    2011-02-15

    Offshore wind energy and ocean energy (i.e. wave and tidal) are at different stages of technology development and deployment, and, as such, they require different approaches for successful deployment. However, regardless of their deployment stage, these technologies may face common hurdles in their way to market competitiveness. IEA-RETD has completed a study with the overall objective to assist policy makers and project developers in a better understanding of these barriers and the specifics of offshore renewable energy and to give them practical guidelines. These include an offshore energy deployment framework, substantiated by evidence-based analyses, and recommendations for future policies design, including best practices for allocation of seafloor rights.

  17. Design and Deployment of Mobile FSO Communication System

    KAUST Repository

    Alheadary, Wael Ghazy; Guo, Yong; Stegenburgs, Edgars; Park, Kihong; Ng, Tien Khee; Ooi, Boon S.; Alouini, Mohamed-Slim

    2017-01-01

    As a potential solution to many applications, we developed a mobile free-space optical (FSO) system that achieves 1Gbps with transmission distance of 70 m. This system needs minimal preparation to be deployed within an hour.

  18. View of the deployed INSAT/PAM-D

    Science.gov (United States)

    1983-01-01

    View of the deployed Indian National Satellite (INSAT) attached to Payload Assist Module (PAM) D drifts above the earth's surface. A faint shadow of the open payload bay can be seen in the top left of the frame.

  19. Connected Vehicle Pilot Deployment Program Phase 2, Data Management Plan

    Science.gov (United States)

    2017-10-17

    This document represents a data management plan that delineates all of the data types and data treatment throughout the New York City Connected Vehicle Pilot Deployment (NYC CVPD). This plan includes an identification of the New York City connected v...

  20. Precision Deployable Mast for the SWOT KaRIn Instrument

    Data.gov (United States)

    National Aeronautics and Space Administration — Design and prototype a lightweight, precision-deployable mast for the Ka-band Radar Interferometer (KaRIn) antennas in the Surface Water and Ocean Topography (SWOT)...

  1. Surface Optimization Techniques for Deployable Reflectors, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — Under this and several other programs, CTD has developed TEMBOREG deployable solid-surface reflectors (TEMBOREG Reflectors) to provide future NASA and Air Force...

  2. Extreme Environment Sampling System Deployment Mechanism, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — Future Venus or Comet mission architectures may feature robotic sampling systems comprised of a Sampling Tool and Deployment Mechanism. Since 2005, Honeybee has been...

  3. The Deployment Experience: Organizational Climate and Work Life

    National Research Council Canada - National Science Library

    Wilcove, Gerry L

    2006-01-01

    ...) and shore personnel (n = 5,032). Results for 2005 showed that deployed personnel had significantly more negative attitudes than shore personnel on several indices, including job satisfaction, quality of command leadership, available...

  4. Deploying ICT with Entrepreneurship Culture can Fight Cyber-Crime ...

    African Journals Online (AJOL)

    Deploying ICT with Entrepreneurship Culture can Fight Cyber-Crime Menace ... Again he innovates, introducing new products & technologies by the ... Keywords: Cyber-crimes, entrepreneurs, compupreneur, firewalls, computer forensics, ICT, ...

  5. Charge Analyzer Responsive Local Oscillations

    Science.gov (United States)

    Krause, Linda Habash; Thornton, Gary

    2015-01-01

    The first transatlantic radio transmission, demonstrated by Marconi in December of 1901, revealed the essential role of the ionosphere for radio communications. This ionized layer of the upper atmosphere controls the amount of radio power transmitted through, reflected off of, and absorbed by the atmospheric medium. Low-frequency radio signals can propagate long distances around the globe via repeated reflections off of the ionosphere and the Earth's surface. Higher frequency radio signals can punch through the ionosphere to be received at orbiting satellites. However, any turbulence in the ionosphere can distort these signals, compromising the performance or even availability of space-based communication and navigations systems. The physics associated with this distortion effect is analogous to the situation when underwater images are distorted by convecting air bubbles. In fact, these ionospheric features are often called 'plasma bubbles' since they exhibit some of the similar behavior as underwater air bubbles. These events, instigated by solar and geomagnetic storms, can cause communication and navigation outages that last for hours. To help understand and predict these outages, a world-wide community of space scientists and technologists are devoted to researching this topic. One aspect of this research is to develop instruments capable of measuring the ionospheric plasma bubbles. Figure 1 shows a photo of the Charge Analyzer Responsive to Local Oscillations (CARLO), a new instrument under development at NASA Marshall Space Flight Center (MSFC). It is a frequency-domain ion spectrum analyzer designed to measure the distributions of ionospheric turbulence from 1 Hz to 10 kHz (i.e., spatial scales from a few kilometers down to a few centimeters). This frequency range is important since it focuses on turbulence scales that affect VHF/UHF satellite communications, GPS systems, and over-the-horizon radar systems. CARLO is based on the flight-proven Plasma Local

  6. Novel Tools in Determining the Physiological Demands and Nutritional Practices of Ontario FireRangers during Fire Deployments.

    Directory of Open Access Journals (Sweden)

    A H Robertson

    Full Text Available The seasonal profession of wildland fire fighting in Canada requires individuals to work in harsh environmental conditions that are physically demanding. The purpose of this study was to use novel technologies to evaluate the physiological demands and nutritional practices of Canadian FireRangers during fire deployments.Participants (n = 21 from a northern Ontario Fire Base volunteered for this study and data collection occurred during the 2014 fire season and included Initial Attack (IA, Project Fire (P, and Fire Base (B deployments. Deployment-specific energy demands and physiological responses were measured using heart-rate variability (HRV monitoring devices (Zephyr BioHarness3 units. Food consumption behaviour and nutrient quantity and quality were captured using audio-video food logs on iPod Touches and analyzed by NutriBase Pro 11 software.Insufficient kilocalories were consumed relative to expenditure for all deployment types. Average daily kilocalories consumed: IA: 3758 (80% consumption rate; P: 2945±888.8; B: 2433±570.8. Average daily kilocalorie expenditure: IA: 4538±106.3; P: 4012±1164.8; B: 2842±649.9. The Average Macronutrient Distribution Range (AMDR for protein was acceptable: 22-25% (across deployment types. Whereas the AMDR for fat and carbohydrates were high: 40-50%; and low: 27-37% respectively, across deployment types.This study is the first to use the described methodology to simultaneously evaluate energy expenditures and nutritional practices in an occupational setting. The results support the use of HRV monitoring and video-food capture, in occupational field settings, to assess job demands. FireRangers expended the most energy during IA, and the least during B deployments. These results indicate the need to develop strategies centered on maintaining physical fitness and improving food practices.

  7. Link Between Deployment Factors and Parenting Stress in Navy Families

    Science.gov (United States)

    2016-04-11

    5a. CONTRACT NUMBER N/A Families 5b. GRANT NUMBER HT9404-13-1-TS05 5c. PROGRAM ELEMENT NUMBER N/A 6. AUTHOR(S) 5d...Purpose: Many service members today are married, and many also have children; deployments affect all members of the military family . The purpose of this...conducted. Findings: As deployment factors increased, parenting stress increased for fathers in the reintegration period, with a potential mediation

  8. Is Military Deployment a Risk Factor for Maternal Depression?

    Science.gov (United States)

    2013-01-01

    679–684. 39. Quevedo LA, Silva RA, Godoy R, et al. The impact of ma- ternal post - partum depression on the language development of children at 12 months...Naval Health Research Center Is Military Deployment A Risk Factor for Maternal Depression ? Stacie Nguyen Cynthia A. LeardMann Besa Smith...Sylvester Road San Diego, California 92106-3521 Original Articles Is Military Deployment a Risk Factor for Maternal Depression ? Stacie Nguyen, MPH

  9. Deployment Models: Towards Eliminating Security Concerns From Cloud Computing

    OpenAIRE

    Zhao, Gansen; Chunming, Rong; Jaatun, Martin Gilje; Sandnes, Frode Eika

    2010-01-01

    Cloud computing has become a popular choice as an alternative to investing new IT systems. When making decisions on adopting cloud computing related solutions, security has always been a major concern. This article summarizes security concerns in cloud computing and proposes five service deployment models to ease these concerns. The proposed models provide different security related features to address different requirements and scenarios and can serve as reference models for deployment. D...

  10. Supporting Military Families with Young Children throughout the Deployment Lifecycle

    Science.gov (United States)

    2017-10-01

    Traumatic Stress Studies (ISTSS) Conference. Chicago, IL. 2. Kritikos*, T.K. & DeVoe, E.R. Relationship quality of recently deployed military...prevention and family orientation of the study . We continue to have impact on multiple disciplinary areas, including social work, psychology , and public...resilience in Active Duty military families through all phases of the deployment cycle. The study will be conducted in three phases. In phase 1

  11. The effect of deployment frequencies on the military divorce rate

    OpenAIRE

    Arenstein, Stacy J.

    2011-01-01

    Approved for public release; distribution is unlimited. The primary goal of this research is to investigate whether the length and frequency of deployments affect the likelihood of divorce. The study uses data from the Contingency Tracking System (CTS) and the Active Duty Military Personnel file. The sample includes all active duty Navy and Marine Corps members from 2000 to 2009. Three models of divorce are estimated, each with a different control for the stress of deployment on the f...

  12. University of Cambridge deploys Procket Networks' PRO/8801

    CERN Multimedia

    2003-01-01

    Procket Networks, a provider of high performance Internet Protocol (IP) technology and products has announced that the University of Cambridge has deployed the PRO/8801(TM) router into its research network to develop industry-leading deep packet inspection applications. The major application for this deployment is to identify and understand new traffic patterns created by large scale scientific computations and downloads such as the GRID (1 page).

  13. Sensor Deployment for Air Pollution Monitoring Using Public Transportation System

    OpenAIRE

    Yu, James J. Q.; Li, Victor O. K.; Lam, Albert Y. S.

    2015-01-01

    Air pollution monitoring is a very popular research topic and many monitoring systems have been developed. In this paper, we formulate the Bus Sensor Deployment Problem (BSDP) to select the bus routes on which sensors are deployed, and we use Chemical Reaction Optimization (CRO) to solve BSDP. CRO is a recently proposed metaheuristic designed to solve a wide range of optimization problems. Using the real world data, namely Hong Kong Island bus route data, we perform a series of simulations an...

  14. Deployment of a pentagonal hollow-rope tensegrity module

    OpenAIRE

    Rhode-Barbarigos , Landolf; Bel Hadj Ali , Nizar; Motro , René; Smith , Ian F.C.

    2011-01-01

    International audience; Tensegrity structures are spatial reticulated structures composed of cables and struts. Tensegrity systems are good candidates for adaptive and deployable structures and thus have applications in various engineering fields. A "hollow-rope" tensegrity system composed of tensegrity-ring modules has been demonstrated by the authors to be a viable system for a pedestrian bridge. This paper focuses on the deployment of pentagonal ring modules. A geometric study is performed...

  15. Kundenorientierte Produktentwicklung mit Hilfe von Quality Function Deployment (QFD)

    OpenAIRE

    Schloske, Alexander

    2011-01-01

    Die Produktentwicklung von heute muss in immer kürzeren Zeiträumen kunden- und kostenorientierte Produkte entwickeln. Zur systematischen Unterstützung dieser Aufgabe im Rahmen der Produktentwicklung wird die Methode Quality Function Deployment (QFD) eingesetzt. Die konsequente Umsetzung der Stimme des Kunden in die Sprache des Unternehmens gelingt mit Quality Function Deployment (QFD). Die Methode wertet systematisch Kundenanforderungen an Produkte aus und führt zu innovativen Lösungen, die s...

  16. Information Analysis Methodology for Border Security Deployment Prioritization and Post Deployment Evaluation

    International Nuclear Information System (INIS)

    Booker, Paul M.; Maple, Scott A.

    2010-01-01

    Due to international commerce, cross-border conflicts, and corruption, a holistic, information driven, approach to border security is required to best understand how resources should be applied to affect sustainable improvements in border security. The ability to transport goods and people by land, sea, and air across international borders with relative ease for legitimate commercial purposes creates a challenging environment to detect illicit smuggling activities that destabilize national level border security. Smuggling activities operated for profit or smuggling operations driven by cross border conflicts where militant or terrorist organizations facilitate the transport of materials and or extremists to advance a cause add complexity to smuggling interdiction efforts. Border security efforts are further hampered when corruption thwarts interdiction efforts or reduces the effectiveness of technology deployed to enhance border security. These issues necessitate the implementation of a holistic approach to border security that leverages all available data. Large amounts of information found in hundreds of thousands of documents can be compiled to assess national or regional borders to identify variables that influence border security. Location data associated with border topics of interest may be extracted and plotted to better characterize the current border security environment for a given country or region. This baseline assessment enables further analysis, but also documents the initial state of border security that can be used to evaluate progress after border security improvements are made. Then, border security threats are prioritized via a systems analysis approach. Mitigation factors to address risks can be developed and evaluated against inhibiting factor such as corruption. This holistic approach to border security helps address the dynamic smuggling interdiction environment where illicit activities divert to a new location that provides less resistance

  17. Radiation energy detector and analyzer

    International Nuclear Information System (INIS)

    Roberts, T.G.

    1981-01-01

    A radiation detector array and a method for measuring the spectral content of radiation. The radiation sensor or detector is an array or stack of thin solid-electrolyte batteries. The batteries, arranged in a stack, may be composed of independent battery cells or may be arranged so that adjacent cells share a common terminal surface. This common surface is possible since the polarity of the batteries with respect to an adjacent battery is unrestricted, allowing a reduction in component parts of the assembly and reducing the overall stack length. Additionally, a test jig or chamber for allowing rapid measurement of the voltage across each battery is disclosed. A multichannel recorder and display may be used to indicate the voltage gradient change across the cells, or a small computer may be used for rapidly converting these voltage readings to a graph of radiation intensity versus wavelength or energy. The behavior of the batteries when used as a radiation detector and analyzer are such that the voltage measurements can be made at leisure after the detector array has been exposed to the radiation, and it is not necessary to make rapid measurements as is now done

  18. Nuclear plant analyzer desktop workstation

    International Nuclear Information System (INIS)

    Beelman, R.J.

    1990-01-01

    In 1983 the U.S. Nuclear Regulatory Commission (USNRC) commissioned the Idaho National Engineering Laboratory (INEL) to develop a Nuclear Plant Analyzer (NPA). The NPA was envisioned as a graphical aid to assist reactor safety analysts in comprehending the results of thermal-hydraulic code calculations. The development was to proceed in three distinct phases culminating in a desktop reactor safety workstation. The desktop NPA is now complete. The desktop NPA is a microcomputer based reactor transient simulation, visualization and analysis tool developed at INEL to assist an analyst in evaluating the transient behavior of nuclear power plants by means of graphic displays. The NPA desktop workstation integrates advanced reactor simulation codes with online computer graphics allowing reactor plant transient simulation and graphical presentation of results. The graphics software, written exclusively in ANSI standard C and FORTRAN 77 and implemented over the UNIX/X-windows operating environment, is modular and is designed to interface to the NRC's suite of advanced thermal-hydraulic codes to the extent allowed by that code. Currently, full, interactive, desktop NPA capabilities are realized only with RELAP5

  19. Using Deduplicating Storage for Efficient Disk Image Deployment

    Directory of Open Access Journals (Sweden)

    Xing Lin

    2015-08-01

    Full Text Available Many clouds and network testbeds use disk images to initialize local storage on their compute devices. Large facilities must manage thousands or more images, requiring significant amounts of storage. At the same time, to provide a good user experience, they must be able to deploy those images quickly. Driven by our experience in operating the Emulab site at the University of Utah---a long-lived and heavily-used testbed---we have created a new service for efficiently storing and deploying disk images. This service exploits the redundant data found in similar images, using deduplication to greatly reduce the amount of physical storage required. In addition to space savings, our system is also designed for highly efficient image deployment---it integrates with an existing highly-optimized disk image deployment system, Frisbee, without significantly increasing the time required to distribute and install images. In this paper, we explain the design of our system and discuss the trade-offs we made to strike a balance between efficient storage and fast disk image deployment. We also propose a new chunking algorithm, called AFC, which enables fixed-size chunking for deduplicating allocated disk sectors. Experimental results show that our system reduces storage requirements by up to 3x while imposing only a negligible runtime overhead on the end-to-end disk-deployment process.

  20. Applications of Dynamic Deployment of Services in Industrial Automation

    Science.gov (United States)

    Candido, Gonçalo; Barata, José; Jammes, François; Colombo, Armando W.

    Service-oriented Architecture (SOA) is becoming a de facto paradigm for business and enterprise integration. SOA is expanding into several domains of application envisioning a unified solution suitable across all different layers of an enterprise infrastructure. The application of SOA based on open web standards can significantly enhance the interoperability and openness of those devices. By embedding a dynamical deployment service even into small field de- vices, it would be either possible to allow machine builders to place built- in services and still allow the integrator to deploy on-the-run the services that best fit his current application. This approach allows the developer to keep his own preferred development language, but still deliver a SOA- compliant application. A dynamic deployment service is envisaged as a fundamental framework to support more complex applications, reducing deployment delays, while increasing overall system agility. As use-case scenario, a dynamic deployment service was implemented over DPWS and WS-Management specifications allowing designing and programming an automation application using IEC61131 languages, and deploying these components as web services into devices.

  1. Detection of parvovirus B19 DNA in blood: Viruses or DNA remnants?

    Science.gov (United States)

    Molenaar-de Backer, M W A; Russcher, A; Kroes, A C M; Koppelman, M H G M; Lanfermeijer, M; Zaaijer, H L

    2016-11-01

    Parvovirus B19 (B19V) DNA can be detected in blood over a long period after acute infection. Several reports associate the presence of B19V DNA with disease, irrespective of timing of the initial B19V infection. This study aims to analyze the properties of B19V DNA in blood, differentiating between bare, non-infectious strands of DNA and B19V DNA in viable virions. Ten blood donors with asymptomatic acute B19V infection were followed and sampled up to 22 months after infection. The samples were treated with and without an endonuclease and tested for B19V DNA, to distinguish between DNA in virions and naked DNA. In the acute phase of infection, high levels of B19V DNA were detected, concurrent with B19V IgM antibodies. B19V DNA apparently was encapsidated, as indicated by resistance to endonuclease degradation. Subsequently, B19V DNA remained detectable for more than one year in all donors at low levels (<10 5 IU/mL). Approximately 150days after infection B19V DNA became degradable by an endonuclease, indicating that this concerned naked DNA. In some donors a second endonuclease-resistant peak occurred. Detection of B19V DNA in blood by PCR does not necessarily imply that B19V replication takes place and that infectious B19V virions are present. We propose that remnant B19V DNA strands can be released from tissues without active replication. This finding urges to reconsider an assumed role of B19V infection mainly based on B19V DNA detection in blood, a much debated subject in clinical syndromes such as myocarditis and arthritis. Copyright © 2016 Elsevier B.V. All rights reserved.

  2. ELIST8: simulating military deployments in Java

    International Nuclear Information System (INIS)

    Van Groningen, C. N.; Blachowicz, D.; Braun, M. D.; Simunich, K. L.; Widing, M. A.

    2002-01-01

    Planning for the transportation of large amounts of equipment, troops, and supplies presents a complex problem. Many options, including modes of transportation, vehicles, facilities, routes, and timing, must be considered. The amount of data involved in generating and analyzing a course of action (e.g., detailed information about military units, logistical infrastructures, and vehicles) is enormous. Software tools are critical in defining and analyzing these plans. Argonne National Laboratory has developed ELIST (Enhanced Logistics Intra-theater Support Tool), a simulation-based decision support system, to assist military planners in determining the logistical feasibility of an intra-theater course of action. The current version of ELIST (v.8) contains a discrete event simulation developed using the Java programming language. Argonne selected Java because of its object-oriented framework, which has greatly facilitated entity and process development within the simulation, and because it fulfills a primary requirement for multi-platform execution. This paper describes the model, including setup and analysis, a high-level architectural design, and an evaluation of Java

  3. Degradation of benzodiazepines after 120 days of EMS deployment.

    Science.gov (United States)

    McMullan, Jason T; Jones, Elizabeth; Barnhart, Bruce; Denninghoff, Kurt; Spaite, Daniel; Zaleski, Erin; Silbergleit, Robert

    2014-01-01

    EMS treatment of status epilepticus improves outcomes, but the benzodiazepine best suited for EMS use is unclear, given potential high environmental temperature exposures. To describe the degradation of diazepam, lorazepam, and midazolam as a function of temperature exposure and time over 120 days of storage on active EMS units. Study boxes containing vials of diazepam, lorazepam, and midazolam were distributed to 4 active EMS units in each of 2 EMS systems in the southwestern United States during May-August 2011. The boxes logged temperature every minute and were stored in EMS units per local agency policy. Two vials of each drug were removed from each box at 30-day intervals and underwent high-performance liquid chromatography to determine drug concentration. Concentration was analyzed as mean (and 95%CI) percent of initial labeled concentration as a function of time and mean kinetic temperature (MKT). 192 samples were collected (2 samples of each drug from each of 4 units per city at 4 time-points). After 120 days, the mean relative concentration (95%CI) of diazepam was 97.0% (95.7-98.2%) and of midazolam was 99.0% (97.7-100.2%). Lorazepam experienced modest degradation by 60 days (95.6% [91.6-99.5%]) and substantial degradation at 90 days (90.3% [85.2-95.4%]) and 120 days (86.5% [80.7-92.3%]). Mean MKT was 31.6°C (95%CI 27.1-36.1). Increasing MKT was associated with greater degradation of lorazepam, but not midazolam or diazepam. Midazolam and diazepam experienced minimal degradation throughout 120 days of EMS deployment in high-heat environments. Lorazepam experienced significant degradation over 120 days and appeared especially sensitive to higher MKT exposure.

  4. Progress on clustered DNA damage in radiation research

    International Nuclear Information System (INIS)

    Yang Li'na; Zhang Hong; Di Cuixia; Zhang Qiuning; Wang Xiaohu

    2012-01-01

    Clustered DNA damage which caused by high LET heavy ion radiation can lead to mutation, tumorigenesis and apoptosis. Promoting apoptosis of cancer cells is always the basis of cancer treatment. Clustered DNA damage has been the hot topic in radiobiology. The detect method is diversity, but there is not a detail and complete protocol to analyze clustered DNA damage. In order to provide reference for clustered DNA damage in the radiotherapy study, the clustered DNA damage characteristics, the latest progresses on clustered DNA damage and the detecting methods are reviewed and discussed in detail in this paper. (authors)

  5. Deployment Experiences of British Army Wives Before, During and After Deployment: Satisfaction with Military Life and Use of Support Networks

    National Research Council Canada - National Science Library

    Dandeker, Christopher; French, Claire; Birtles, Catherine; Wessely, S

    2006-01-01

    Introduction and Aims: During deployments, Service wives have to adapt to being alone and taking sole responsibility for their families and house-holds whilst dealing with the additional stress about whether their loved ones will return...

  6. Two potential Petunia hybrida mitochondrial DNA replication origins show structural and in vitro functional homology with the animal mitochondrial DNA heavy and light strand replication origins

    NARCIS (Netherlands)

    Haas, Jan M. de; Hille, Jacques; Kors, Frank; Meer, Bert van der; Kool, Ad J.; Folkerts, Otto; Nijkamp, H. John J.

    1991-01-01

    Four Petunia hybrida mitochondrial (mt) DNA fragments have been isolated, sequenced, localized on the physical map and analyzed for their ability to initiate specific DNA synthesis. When all four mtDNA fragments were tested as templates in an in vitro DNA synthesizing lysate system, developed from

  7. Analyzing Arthropods for the Presence of Bacteria

    OpenAIRE

    Andrews, Elizabeth S.

    2013-01-01

    Bacteria within arthropods can be identified using culture-independent methods. This unit describes protocols for surface sterilization of arthropods, DNA extraction of whole bodies and tissues, touchdown PCR amplification using 16S rDNA general bacteria primers and profiling the bacterial community using denaturing gradient gel electrophoresis.

  8. IEA Wind Task 23 Offshore Wind Technology and Deployment. Subtask 1 Experience with Critical Deployment Issues. Final Technical Report

    OpenAIRE

    Lemming, Jørgen Kjærgaard

    2010-01-01

    The final report for IEA Wind Task 23, Offshore Wind Energy Technology and Deployment, is made up of two separate reports: Subtask 1: Experience with Critical Deployment Issues and Subtask 2: Offshore Code Comparison Collaborative (OC3). The Subtask 1 report included here provides background information and objectives of Task 23. It specifically discusses ecological issues and regulation, electrical system integration and offshore wind, external conditions, and key conclusions for Subtask 1. ...

  9. JavaScript DNA translator: DNA-aligned protein translations.

    Science.gov (United States)

    Perry, William L

    2002-12-01

    There are many instances in molecular biology when it is necessary to identify ORFs in a DNA sequence. While programs exist for displaying protein translations in multiple ORFs in alignment with a DNA sequence, they are often expensive, exist as add-ons to software that must be purchased, or are only compatible with a particular operating system. JavaScript DNA Translator is a shareware application written in JavaScript, a scripting language interpreted by the Netscape Communicator and Internet Explorer Web browsers, which makes it compatible with several different operating systems. While the program uses a familiar Web page interface, it requires no connection to the Internet since calculations are performed on the user's own computer. The program analyzes one or multiple DNA sequences and generates translations in up to six reading frames aligned to a DNA sequence, in addition to displaying translations as separate sequences in FASTA format. ORFs within a reading frame can also be displayed as separate sequences. Flexible formatting options are provided, including the ability to hide ORFs below a minimum size specified by the user. The program is available free of charge at the BioTechniques Software Library (www.Biotechniques.com).

  10. Gender differences in the effects of deployment-related stressors and pre-deployment risk factors on the development of PTSD symptoms in National Guard Soldiers deployed to Iraq and Afghanistan.

    Science.gov (United States)

    Polusny, Melissa A; Kumpula, Mandy J; Meis, Laura A; Erbes, Christopher R; Arbisi, Paul A; Murdoch, Maureen; Thuras, Paul; Kehle-Forbes, Shannon M; Johnson, Alexandria K

    2014-02-01

    Although women in the military are exposed to combat and its aftermath, little is known about whether combat as well as pre-deployment risk/protective factors differentially predict post-deployment PTSD symptoms among women compared to men. The current study assesses the influence of combat-related stressors and pre-deployment risk/protective factors on women's risk of developing PTSD symptoms following deployment relative to men's risk. Participants were 801 US National Guard Soldiers (712 men, 89 women) deployed to Iraq or Afghanistan who completed measures of potential risk/protective factors and PTSD symptoms one month before deployment (Time 1) and measures of deployment-related stressors and PTSD symptoms about 2-3 months after returning from deployment (Time 2). Men reported greater exposure to combat situations than women, while women reported greater sexual stressors during deployment than men. Exposure to the aftermath of combat (e.g., witnessing injured/dying people) did not differ by gender. At Time 2, women reported more severe PTSD symptoms and higher rates of probable PTSD than did men. Gender remained a predictor of higher PTSD symptoms after accounting for pre-deployment symptoms, prior interpersonal victimization, and combat related stressors. Gender moderated the association between several risk factors (combat-related stressors, prior interpersonal victimization, lack of unit support and pre-deployment concerns about life/family disruptions) and post-deployment PTSD symptoms. Elevated PTSD symptoms among female service members were not explained simply by gender differences in pre-deployment or deployment-related risk factors. Combat related stressors, prior interpersonal victimization, and pre-deployment concerns about life and family disruptions during deployment were differentially associated with greater post-deployment PTSD symptoms for women than men. Copyright © 2013 The Authors. Published by Elsevier Ltd.. All rights reserved.

  11. Assessment of a Post-deployment Yellow Ribbon Reintegration Program for National Guard Members and Supporters

    Science.gov (United States)

    Scherrer, Jeffrey F.; Widner, Greg; Shroff, Manan; Matthieu, Monica; Balan, Sundari; van den Berk-Clark, Carissa; Price, Rumi Kato

    2014-01-01

    The Yellow Ribbon Reintegration Program (YRRP) was created to meet the needs of National Guard members and their families throughout the deployment cycle. This study examined the perceived utility of the YRRP’s delivery of information and assistance during the post-deployment reintegration period by National Guard members and accompanying supporters who were mostly spouses. Over 22 months, from 10 YRRP events, 683 service members and 411 supporters completed questionnaires immediately after the YRRP. We analyzed questions on information and help provision, timeliness and concerns related to education, employment, legal, family, and health. Service members and supporters most often endorsed education needs being met (76.8% and 78.2% respectively) and were least likely to endorse legal needs being met (63.5% and 60% respectively). Significantly more supporters than service members (p family. Results suggest the YRRP fills gaps in supporter knowledge and provides needed information and resources to most National Guard families 2-4 months after a deployment. PMID:25373071

  12. Using Docker Compose for the Simple Deployment of an Integrated Drug Target Screening Platform

    Directory of Open Access Journals (Sweden)

    List Markus

    2017-06-01

    Full Text Available Docker virtualization allows for software tools to be executed in an isolated and controlled environment referred to as a container. In Docker containers, dependencies are provided exactly as intended by the developer and, consequently, they simplify the distribution of scientific software and foster reproducible research. The Docker paradigm is that each container encapsulates one particular software tool. However, to analyze complex biomedical data sets, it is often necessary to combine several software tools into elaborate workflows. To address this challenge, several Docker containers need to be instantiated and properly integrated, which complicates the software deployment process unnecessarily. Here, we demonstrate how an extension to Docker, Docker compose, can be used to mitigate these problems by providing a unified setup routine that deploys several tools in an integrated fashion. We demonstrate the power of this approach by example of a Docker compose setup for a drug target screening platform consisting of five integrated web applications and shared infrastructure, deployable in just two lines of codes.

  13. Using Docker Compose for the Simple Deployment of an Integrated Drug Target Screening Platform.

    Science.gov (United States)

    List, Markus

    2017-06-10

    Docker virtualization allows for software tools to be executed in an isolated and controlled environment referred to as a container. In Docker containers, dependencies are provided exactly as intended by the developer and, consequently, they simplify the distribution of scientific software and foster reproducible research. The Docker paradigm is that each container encapsulates one particular software tool. However, to analyze complex biomedical data sets, it is often necessary to combine several software tools into elaborate workflows. To address this challenge, several Docker containers need to be instantiated and properly integrated, which complicates the software deployment process unnecessarily. Here, we demonstrate how an extension to Docker, Docker compose, can be used to mitigate these problems by providing a unified setup routine that deploys several tools in an integrated fashion. We demonstrate the power of this approach by example of a Docker compose setup for a drug target screening platform consisting of five integrated web applications and shared infrastructure, deployable in just two lines of codes.

  14. An ARM Mobile Facility Designed for Marine Deployments

    Science.gov (United States)

    Wiscombe, W. J.

    2007-05-01

    The U.S. Dept. of Energy's ARM (Atmospheric Radiation Measurements) Program is designing a Mobile Facility exclusively for marine deployments. This marine facility is patterned after ARM's land Mobile Facility, which had its inaugural deployment at Point Reyes, California, in 2005, followed by deployments to Niger in 2006 and Germany in 2007 (ongoing), and a planned deployment to China in 2008. These facilities are primarily intended for the study of clouds, radiation, aerosols, and surface processes with a goal to include these processes accurately in climate models. They are preferably embedded within larger field campaigns which provide context. They carry extensive instrumentation (in several large containers) including: cloud radar, lidar, microwave radiometers, infrared spectrometers, broadband and narrowband radiometers, sonde-launching facilities, extensive surface aerosol measurements, sky imagers, and surface latent and sensible heat flux devices. ARM's Mobile Facilities are designed for 6-10 month deployments in order to capture climatically-relevant datasets. They are available to any scientist, U.S. or international, who wishes to submit a proposal during the annual Spring call. The marine facility will be adapted to, and ruggedized for, the harsh marine environment and will add a scanning two-frequency radar, a boundary-layer wind profiler, a shortwave spectrometer, and aerosol instrumentation adapted to typical marine aerosols like sea salt. Plans also include the use of roving small UAVs, automated small boats, and undersea autonomous vehicles in order to address the point-to-area-average problem which is so crucial for informing climate models. Initial deployments are planned for small islands in climatically- interesting cloud regimes, followed by deployments on oceanic platforms (like decommissioned oil rigs and the quasi-permanent platform of this session's title) and eventually on large ships like car carriers plying routine routes.

  15. Ultrasound-Guided Cervical Medial Branch Radiofrequency Neurotomy: Can Multitined Deployment Cannulae Be the Solution?

    Science.gov (United States)

    Finlayson, Roderick J; Thonnagith, Atikun; Elgueta, Maria Francisca; Perez, Jordi; Etheridge, John-Paul B; Tran, De Q H

    Novel multitined cannulae constitute an attractive option for ultrasound-guided radiofrequency neurotomy of cervical medial branches. The deployment tines increase the cannula's active area, thus altering its lesion size. Despite their theoretical benefits, multitined cannulae have not been assessed. In this bench study, we sought to investigate the lesions produced by a standard 18-gauge and 2 commercially available multitined deployment cannulae. We created ex vivo models to evaluate lesion morphology at a periosteal interface using approach angles likely to be encountered during an ultrasound-guided technique. Two ex vivo models were assembled using chicken breast tissue and bovine tibia. Monopolar lesions were carried out with 3 commercially available cannulae (18-gauge curved [S], 17-gauge with laterally deploying tines [N], and 18-gauge with distally deploying tines [T]). All cannulae were positioned at 0, 25, 45, and 90 degrees to the periosteal plane. For each angulation and cannula, 2 series of measurements were recorded to document lesion morphology in the axial and sagittal planes. Data collected included the lesion's surface area, shape, and dimensions relative to the needle tip. A total of 240 lesions were analyzed. The performances of S and N cannulae were significantly affected by approach angle, with lesion size decreasing as the angle increased. In contrast, T cannulae displayed similar lesion surface areas at 0 and 90 degrees. The multitined N and T cannulae produced the largest lesions at 0/25 and 90 degrees, respectively. Lesion height varied inversely according to approach angle for S and N cannulae, whereas T cannulae displayed stable characteristics. Unlike their S and N counterparts, T cannulae demonstrated stable lesion characteristics at varying approach angles.

  16. Well-Being Analysis of Power Systems Considering Increasing Deployment of Gas Turbines

    Directory of Open Access Journals (Sweden)

    Bomiao Liang

    2017-07-01

    Full Text Available With the significant decrease in natural gas prices in many parts of the world, the employment of gas turbine (GT units has increased steadily in recent years. The ever-increasing deployment of GT units is strengthening the interconnections between electric power and natural gas systems, which could provide a higher level of operational flexibility and reliability. As a result, the planning and operation issues in the interconnected electric power and natural gas systems have aroused concern. In these circumstances, the impacts of increasing deployment of GT units in power system operation are studied and evaluated through well-being analysis (WBA. The fast responsive characteristics of GT units are analyzed first, and the definition and adaption of WBA in a power system with increasing deployment of GT units are addressed. Then the equivalent reserve capacity of GT units is estimated, taking demand fluctuations, commitment plans, and operational risks of GT units into account. The WBA of a power system with increasing deployment of GT units is conducted considering the uncertainties of system operation states and renewable energy sources. Finally, the proposed methods are validated through an integrated version of the IEEE 118-bus power system and a 10-bus natural gas system, and the impacts of GT units on power system security under various penetration levels are examined. Simulation results demonstrate that the role of a GT unit as a low-cost electricity producer may conflict with its role as a reserve provider, but through maintaining a proper proportion of idle GT capacities for reserve, the well-being performance of the power system concerned can be significantly improved.

  17. Online fathering: the experience of first-time fatherhood in combat-deployed troops.

    Science.gov (United States)

    Schachman, Kathleen A

    2010-01-01

    More than 90% of fathers in the United States attend the births of their children. Each year, thousands of fathers are absent during this important life transition because of military deployment in combat regions; however, it is unknown how this population experiences new fatherhood. The purpose of this study was to explore the lived experience of first-time fatherhood from the unique perspective of military men deployed to combat regions during birth. A phenomenological approach was used. Seventeen men who were stationed in Okinawa, Japan, and had returned recently from a combat deployment participated. Unstructured, in-depth interviews were conducted 2 to 6 months after the births. Interviews were audiotaped, transcribed, and analyzed using Colaizzi's method. Disruption of the protector and provider role was a main theme that encompassed four theme clusters: (a) worry-a traumatic and lonely childbirth; (b) lost opportunity; (c) guilt-an absent father; and (d) fear of death and dismemberment-who will be the father? Although their absence interfered with their ability to fulfill the fatherhood role as they perceived it, this was offset by the theme cluster Communication: The ties that bind, highlighting the role of online communication with their partner (e.g., e-mail, instant messaging, Facebook, blogs, and chat rooms) in restoring balance to the protector and provider role. Insight is provided into the needs of first-time fathers who are combat-deployed during the births of their babies. Understanding these experiences assists nurses in identifying better ways to prepare and to support men in an involved fatherhood role, despite the limitations of a stressful combat environment and geographic separation. This information can set the stage for a healthy reunion, which may take place at military bases and within communities across the globe, and thus is of benefit to all nurses working with military families.

  18. The impact of antecedent trauma exposure and mental health symptoms on the post-deployment mental health of Afghanistan-deployed Australian troops.

    Science.gov (United States)

    Searle, Amelia K; Van Hooff, Miranda; Lawrence-Wood, Ellie R; Grace, Blair S; Saccone, Elizabeth J; Davy, Carol P; Lorimer, Michelle; McFarlane, Alexander C

    2017-10-01

    Both traumatic deployment experiences and antecedent traumas increase personnel's risk of developing PTSD and depression. However, only cross-sectional studies have assessed whether antecedent trauma moderates stress reactions to deployment experiences. This study prospectively examines whether antecedent trauma moderates the association between deployment trauma and post-deployment PTSD and depressive symptoms after accounting for antecedent mental health problems, in a large Australian Defence Force (ADF) sample. In the ADF Middle East Area of Operations Prospective Study, currently-serving military personnel deployed to Afghanistan across 2010-2012 (n = 1122) completed self-reported measures at pre-deployment and post-deployment. Within multivariable regressions, associations between deployment trauma and PTSD and depressive symptoms at post-deployment were stronger for personnel with greater antecedent trauma. However, once adjusting for antecedent mental health problems, these significant interaction effects disappeared. Instead, deployment-related trauma and antecedent mental health problems showed direct associations with post-deployment mental health problems. Antecedent trauma was also indirectly associated with post-deployment mental health problems through antecedent mental health problems. Similar associations were seen with prior combat exposure as a moderator. Antecedent and deployment trauma were reported retrospectively. Self-reports may also suffer from social desirability bias, especially at pre-deployment. Our main effects results support the pervasive and cumulative negative effect of trauma on military personnel, regardless of its source. While antecedent trauma does not amplify personnel's psychological response to deployment trauma, it is indirectly associated with increased post-deployment mental health problems. Antecedent mental health should be considered within pre-deployment prevention programs, and deployment-trauma within post

  19. Effect of different materials in the performance of solar reactors deployed in Jaiba, Minas Gerais state

    Energy Technology Data Exchange (ETDEWEB)

    Sartori, Marcia Aparecida; Soares, Antonio Alves; Soares, Adilson Rodrigues; Batista, Rafael Oliveira; Leite, Caio Vinicius [Universidade Federal de Vicosa (DEA/UFV), MG (Brazil). Dept. de Engenharia Agricola

    2008-07-01

    This study aimed to analyze the effect of different materials (masonry, butyl canvas and fiberglass) in the performance of solar reactors deployed in the city of Jaiba, Minas Gerais State. To do so, mini-stations to treat the domestic sewage were assembled. During the tests, samples of the effluent were collected upstream and downstream of the septic tank and the solar reactor. Fecal coliforms, BOD and COD were quantified in laboratory. The results indicated that the materials tested for construction of the reactor did not influence the solar disinfection of fecal coliforms. (author)

  20. On the road : non-fossil fuel deployment for the public bus fleet of Sweden

    OpenAIRE

    Xylia, Maria; Silveira, Semida

    2015-01-01

    The public transport sector in Sweden has set a target to run 90% of its total vehicle-kilometers on renewable fuels by 2020, and double its market share in the long term. The focus of this paper is the adoption of renewable fuels in public bus fleets. Data for all 21 Swedish counties were gathered and analyzed, mapping the bus fleets’ condition in relation to renewable fuel deployment, CO2 emissions and energy efficiency. The main factors affecting fuel choices in the bus fleets were investi...

  1. Deploying and implementing Inclusive Physical Education

    Directory of Open Access Journals (Sweden)

    Eliana Lúcia Ferreira

    2014-04-01

    Full Text Available Physical Education, as a curricular component of basic education, is not indifferent to the movement of Inclusive physical education. Differentiated bodies are conquering new social spaces. Our aim through this investigation is to identify the main historical practices regarding Brazilian Policy of Inclusive Education and to point out proposals to implement inclusive Physical education. Our methodology consists of a descriptive study based on two main axes. The first axis is related to a historical discussion whose source was national documents of reference about Inclusive Physical Education. The second axis is related to the experience of 2000 teachers; we have the occasion to analyze their practices on the subject of Inclusive physical education. As a result, this investigation also develops a proposal to inclusive physical education; this proposal is established in another dimension and understanding of work and movement. Concerning the final considerations we suggest a disruption with already crystallized bodily practices and we suggest actions respecting individual differences. Moreover, we point out the fact that Inclusive Physical Education has advocated another meaning for the body, in favor of a more collective physical education and searching for activities in which individuality prevails.

  2. Comparison of electron cloud mitigating coatings using retarding field analyzers

    Energy Technology Data Exchange (ETDEWEB)

    Calvey, J.R., E-mail: jrc97@cornell.edu; Hartung, W.; Li, Y.; Livezey, J.A.; Makita, J.; Palmer, M.A.; Rubin, D.

    2014-10-01

    In 2008, the Cornell Electron Storage Ring (CESR) was reconfigured to serve as a test accelerator (CESRTA) for next generation lepton colliders, in particular for the ILC damping ring. A significant part of this program has been the installation of diagnostic devices to measure and quantify the electron cloud effect, a potential limiting factor in these machines. One such device is the Retarding Field Analyzer (RFA), which provides information on the local electron cloud density and energy distribution. Several different styles of RFAs have been designed, tested, and deployed throughout the CESR ring. They have been used to study the growth of the cloud in different beam conditions, and to evaluate the efficacy of different mitigation techniques. This paper will provide an overview of RFA results obtained in a magnetic field free environment.

  3. Standardization of transportation classes for object-oriented deployment simulations.

    Energy Technology Data Exchange (ETDEWEB)

    Burke, J. F., Jr.; Howard, D. L.; Jackson, J.; Macal, C. M.; Nevins, M. R.; Van Groningen, C. N.

    1999-07-30

    Many recent efforts to integrate transportation and deployment simulations, although beneficial, have lacked a feature vital for seamless integration: a common data class representation. It is an objective of the Department of Defense (DoD) to standardize all classes used in object-oriented deployment simulations by developing a standard class attribute representation and behavior for all deployment simulations that rely on an underlying class representation. The Extensive Hierarchy and Object Representation for Transportation Simulations (EXHORT) is a collection of three hierarchies that together will constitute a standard and consistent class attribute representation and behavior that could be used directly by a large set of deployment simulations. The first hierarchy is the Transportation Class Hierarchy (TCH), which describes a significant portion of the defense transportation system; the other two deal with infrastructure and resource classes. EXHORT will allow deployment simulations to use the same set of underlying class data, ensure transparent exchanges, reduce the effort needed to integrate simulations, and permit a detailed analysis of the defense transportation system. This paper describes EXHORT's first hierarchy, the TCH, and provides a rationale for why it is a helpful tool for modeling major portions of the defense transportation system.

  4. Post-deployment family violence among UK military personnel.

    Science.gov (United States)

    Kwan, Jamie; Jones, Margaret; Somaini, Greta; Hull, Lisa; Wessely, Simon; Fear, Nicola T; MacManus, Deirdre

    2017-12-19

    Research into violence among military personnel has not differentiated between stranger- and family-directed violence. While military factors (combat exposure and post-deployment mental health problems) are risk factors for general violence, there has been limited research on their impact on violence within the family environment. This study aims to compare the prevalence of family-directed and stranger-directed violence among a deployed sample of UK military personnel and to explore risk factors associated with both family- and stranger-directed violence. This study utilised data from a large cohort study which collected information by questionnaire from a representative sample of randomly selected deployed UK military personnel (n = 6711). The prevalence of family violence immediately following return from deployment was 3.6% and 7.8% for stranger violence. Family violence was significantly associated with having left service, while stranger violence was associated with younger age, male gender, being single, having a history of antisocial behaviour as well as having left service. Deployment in a combat role was significantly associated with both family and stranger violence after adjustment for confounders [adjusted odds ratio (aOR) = 1.92 (1.25-2.94), p = 0.003 and aOR = 1.77 (1.31-2.40), p violence both inside and outside the family environment and should be considered in violence reduction programmes for military personnel. Further research using a validated measurement tool for family violence would improve comparability with other research.

  5. Automated Deployment of Advanced Controls and Analytics in Buildings

    Science.gov (United States)

    Pritoni, Marco

    Buildings use 40% of primary energy in the US. Recent studies show that developing energy analytics and enhancing control strategies can significantly improve their energy performance. However, the deployment of advanced control software applications has been mostly limited to academic studies. Larger-scale implementations are prevented by the significant engineering time and customization required, due to significant differences among buildings. This study demonstrates how physics-inspired data-driven models can be used to develop portable analytics and control applications for buildings. Specifically, I demonstrate application of these models in all phases of the deployment of advanced controls and analytics in buildings: in the first phase, "Site Preparation and Interface with Legacy Systems" I used models to discover or map relationships among building components, automatically gathering metadata (information about data points) necessary to run the applications. During the second phase: "Application Deployment and Commissioning", models automatically learn system parameters, used for advanced controls and analytics. In the third phase: "Continuous Monitoring and Verification" I utilized models to automatically measure the energy performance of a building that has implemented advanced control strategies. In the conclusions, I discuss future challenges and suggest potential strategies for these innovative control systems to be widely deployed in the market. This dissertation provides useful new tools in terms of procedures, algorithms, and models to facilitate the automation of deployment of advanced controls and analytics and accelerate their wide adoption in buildings.

  6. Biomarkers of post-deployment resilience among military service members

    Directory of Open Access Journals (Sweden)

    Krista B. Highland

    2015-01-01

    Full Text Available The development of PTSD after military deployment is influenced by a combination of biopsychosocial risk and resilience factors. In particular, physiological factors may mark risk for symptom progression or resiliency. Research in civilian populations suggests elevated catecholamines after trauma are associated with PTSD months following the trauma. However, less is known regarding physiological markers of PTSD resilience among post-deployment service members (SM. We therefore assessed whether catecholamines obtained shortly after deployment were associated with combat-related PTSD symptoms three months later. Eighty-seven SMs completed the Clinician-Administered PTSD Scale for DSM-IV and blood draws within two months after return from deployment to Iraq or Afghanistan (“Time 1” or “T1” and three months later (“Time 2” or “T2”. Linear regression analyses demonstrated that lower norepinephrine at T1 was associated with lower PTSD symptoms at T2. In particular, T1 norepinephrine was positively associated with T2 symptom intensity and avoidance symptoms. The present findings represent a biologically-informed method of assessing PTSD resilience after deployment, which may aid clinicians in providing tailored treatments for those in the greatest need. Further research is needed to validate these findings and incorporate physiological measures within an assessment battery.

  7. Supporting deployed operations: are military nurses gaining the relevant experience from MDHUs to be competent in deployed operations?

    Science.gov (United States)

    Beaumont, Steven P; Allan, Helen T

    2014-01-01

    To explore how peacetime employment of military nurses in the UK National Health Service Medical Defence Hospital Units prepares them to be competent to practise in their role on deployment. Military secondary care nurses are employed within UK National Health Service Trusts to gain clinical experience that will be relevant to their military nursing role. A two-stage grounded theory study using mixed methods: postal questionnaire survey and in-depth interviews. In stage one a postal questionnaire was distributed to all serving military nurses. Stage two involved 12 semi-structured interviews. The data from both parts of the study were analysed using grounded theory. Four categories and one core category were identified, which suggested that participants did not feel fully prepared for deployment. Their feelings of preparedness increased with deployment experience and decreased when the nature of injuries seen on deployment changed. Respondents argued that even when unprepared, they did not feel incompetent. The findings suggest that the peacetime clinical experience gained in the National Health Service did not always develop the necessary competencies to carry out roles as military nurses on deployment. This study highlights the unique role of military nurses. We discuss these findings in the light of the literature on competency and expertise. The military nurses in this study did not feel fully prepared for deployed operations. We propose a new model for how military nurses could gain relevant experience from their National Health Service placements. National Health Service clinical placements need to be reassessed regularly to ensure that they are meeting military nurses' clinical requirements. Experiences of nurses returning from deployment could be shared and used as a basis for reflection and learning within National Health Service Trusts and also inform decisions regarding the appropriateness of clinical placements for qualified military nurses. © 2012

  8. Deployment of SIP in MANET: challenges and circumvention

    Directory of Open Access Journals (Sweden)

    Abdelhamid Salma R.

    2017-01-01

    Full Text Available The immense growth in wireless network applications has encouraged the researchers to enhance and propose new approaches that facilitate the deployment of the widely used services, protocols, and applications of the wired networking area in the wireless networks. Among which, the Session Initiation Protocol (SIP is a signaling protocol that allows the establishment of multimedia sessions and calls between different parties. SIP functionality totally depends on a centralized infrastructure, and complexity arises when deploying such a protocol in a special type of wireless networks, namely Mobile Ad-hoc Networks (MANET, due to the absence of a centralized infrastructure, and the dynamic topology of the later. This paper highlights the the challenges arising when deploying SIP in MANETs and presents an overview of different proposed approaches to overcome these challenges.

  9. Optimal and Approximate Approaches for Deployment of Heterogeneous Sensing Devices

    Directory of Open Access Journals (Sweden)

    Rabie Ramadan

    2007-04-01

    Full Text Available A modeling framework for the problem of deploying a set of heterogeneous sensors in a field with time-varying differential surveillance requirements is presented. The problem is formulated as mixed integer mathematical program with the objective to maximize coverage of a given field. Two metaheuristics are used to solve this problem. The first heuristic adopts a genetic algorithm (GA approach while the second heuristic implements a simulated annealing (SA algorithm. A set of experiments is used to illustrate the capabilities of the developed models and to compare their performance. The experiments investigate the effect of parameters related to the size of the sensor deployment problem including number of deployed sensors, size of the monitored field, and length of the monitoring horizon. They also examine several endogenous parameters related to the developed GA and SA algorithms.

  10. Novel large deployable antenna backing structure concepts for foldable reflectors

    Science.gov (United States)

    Fraux, V.; Lawton, M.; Reveles, J. R.; You, Z.

    2013-12-01

    This paper describes a number of large deployable antenna (LDA) reflector structure concepts developed at EnerSys-ABSL. Furthermore, EnerSys-ABSL has confirmed the desire to build a breadboard demonstrator of a backing deployable structure for a foldable reflector in the diameter range of 4-9 m. As part of this project EnerSys-ABSL has explored five novel deployable structure concepts. This paper presents the top level definition of these concepts together with the requirements considered in the design and selection of the preferred candidate. These new concepts are described and then compared through a trade-off analysis to identify the most suitable concept that EnerSys-ABSL would like to consider for the breadboard demonstrator. Finally, the kinematics of the chosen concept is described in more detail and future steps in the development process are highlighted.

  11. Security-by-Experiment: Lessons from Responsible Deployment in Cyberspace.

    Science.gov (United States)

    Pieters, Wolter; Hadžiosmanović, Dina; Dechesne, Francien

    2016-06-01

    Conceiving new technologies as social experiments is a means to discuss responsible deployment of technologies that may have unknown and potentially harmful side-effects. Thus far, the uncertain outcomes addressed in the paradigm of new technologies as social experiments have been mostly safety-related, meaning that potential harm is caused by the design plus accidental events in the environment. In some domains, such as cyberspace, adversarial agents (attackers) may be at least as important when it comes to undesirable effects of deployed technologies. In such cases, conditions for responsible experimentation may need to be implemented differently, as attackers behave strategically rather than probabilistically. In this contribution, we outline how adversarial aspects are already taken into account in technology deployment in the field of cyber security, and what the paradigm of new technologies as social experiments can learn from this. In particular, we show the importance of adversarial roles in social experiments with new technologies.

  12. Deployment of a Grid-based Medical Imaging Application

    CERN Document Server

    Amendolia, S R; Frate, C; Gálvez, J; Hassan, W; Hauer, T; Manset, D; McClatchey, R; Odeh, M; Rogulin, D; Solomonides, T; Warren, R

    2005-01-01

    The MammoGrid project has deployed its Service-Oriented Architecture (SOA)-based Grid application in a real environment comprising actual participating hospitals. The resultant setup is currently being exploited to conduct rigorous in-house tests in the first phase before handing over the setup to the actual clinicians to get their feedback. This paper elaborates the deployment details and the experiences acquired during this phase of the project. Finally the strategy regarding migration to an upcoming middleware from EGEE project will be described. This paper concludes by highlighting some of the potential areas of future work.

  13. Improvements for rotary viscous dampers used in spacecraft deployment mechanisms

    Science.gov (United States)

    Stewart, Alphonso; Powers, Charles; Lyons, Ron

    1998-01-01

    During component level thermal-vacuum deployment testing of eight rotary viscous dampers for the Tropical Rainfall Measuring Mission (TRMM) satellite, all the dampers failed to provide damping during a region of the deployment. Radiographic examination showed that air in the damping fluid caused the undamped motion when the dampers were operated in a vacuum environment. Improvements in the procedure used to fill the dampers with damping fluid, the installation of a Viton vacuum seal in the damper cover, and improved screening techniques eliminated the problem.

  14. Hezbollah Rockets and Missiles: Deployment and Defence Programme

    Directory of Open Access Journals (Sweden)

    Ladislav Kulhánek

    2018-01-01

    Full Text Available The paper addresses the issue of the proliferation of the rocket technology deployed in guerrilla warfare throughout the Near East. It evaluates assumptions and identifies potential regressions with respect to the most recent hot phase in the violent conflict between Hezbollah and Israel, with a focus on primary methods based on rocket shelling and resistance efforts. In comparing the two military forces, Israel emerges as the stronger, even if artillery and tactical ballistic missiles with warheads containing substances defined as weapons of mass destruction were to be deployed as an extreme first measure by Hezbollah, in which case an Israeli or American response would destroy at least parts of Lebanon.

  15. Base Station Antenna Pattern Distortion in Practical Urban Deployment Scenarios

    DEFF Research Database (Denmark)

    Rodriguez Larrad, Ignacio; Nguyen, Huan Cong; Sørensen, Troels Bundgaard

    2014-01-01

    In real urban deployments, base station antennas are typically not placed in free space conditions. Therefore, the radiation pattern can be affected by mounting structures and nearby obstacles located in the proximity of the antenna (near-field), which are often not taken into consideration. Also...... presents a combination of near-field and far-field simulations aimed to provide an overview of the distortion experienced by the base station antenna pattern in two different urban deployment scenarios: rooftop and telecommunications tower. The study illustrates how, in comparison with the near...

  16. Market deployment strategies for photovoltaics: an international review

    International Nuclear Information System (INIS)

    Haas, R.

    2003-01-01

    In the last decade of the 20th century a wide variety of deployment strategies and dissemination programmes for grid-connected PV systems in the built environment has been launched by quite different organizations and institutions. Governmental bodies on national and local levels have launched strategies, as have electric utilities and NGOs. The core objective of this paper is to document and evaluate the most important past and current market deployment strategies for the broader dissemination of grid-connected PV systems in the built environment. (author)

  17. Intelligent quality function deployment system in concurrent engineering environment

    Science.gov (United States)

    Lin, Zhihang; Che, Ada

    1998-10-01

    This paper describes work being undertaken in the development of an intelligent distributed quality function deployment (IDQFD) system, which supports product design team to transfer and deployment the `Voice of Customer' through `House of Quality' into the various stages of product planning, engineering and manufacturing. The requirement modeling of products, the optimization in QFD are indicated. The framework of the system, including QFD tools and platform for distributed collaborative work in QFD, is described. The strategy and methods for the collaboration processing in QFD process are presented. It shows promise for application in practice.

  18. Cognitive ability and risk of post-traumatic stress disorder after military deployment

    DEFF Research Database (Denmark)

    Nissen, Lars R.; Karstoft, Karen-Inge; Vedtofte, Mia S.

    2017-01-01

    Background: Studies of the association between pre-deployment cognitive ability and post-deployment post-traumatic stress disorder (PTSD) have shown mixed results. Aims: To study the influence of pre-deployment cognitive ability on PTSD symptoms 6-8 months post-deployment in a large population...

  19. 49 CFR 268.3 - Different phases of the Maglev Deployment Program.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Different phases of the Maglev Deployment Program... DEPLOYMENT PROGRAM Overview § 268.3 Different phases of the Maglev Deployment Program. (a) The Maglev... deadlines—based on the progress of the Maglev Deployment Program; grantees will be notified accordingly. (b...

  20. 49 CFR 268.5 - Federal funding sources for the Maglev Deployment Program.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Federal funding sources for the Maglev Deployment... TECHNOLOGY DEPLOYMENT PROGRAM Overview § 268.5 Federal funding sources for the Maglev Deployment Program. (a) Federal Maglev Funds. Section 322 of Title 23 provides for the following funds for the Maglev Deployment...

  1. Deployment of Mobile Learning Course Materials to Android Powered Mobile Devices

    Science.gov (United States)

    Chao, Lee

    2012-01-01

    The objective of this article is to facilitate mobile teaching and learning by providing an alternative course material deployment method. This article suggests a course material deployment platform for small universities or individual instructors. Different from traditional course material deployment methods, the method discussed deploys course…

  2. 15 CFR 270.102 - Conditions for establishment and deployment of a Team.

    Science.gov (United States)

    2010-01-01

    ... deployment of a Team. 270.102 Section 270.102 Commerce and Foreign Trade Regulations Relating to Commerce and... SAFETY TEAMS NATIONAL CONSTRUCTION SAFETY TEAMS Establishment and Deployment of Teams § 270.102 Conditions for establishment and deployment of a Team. (a) The Director may establish a Team for deployment...

  3. Characterization of a Dairy Gyr herd with respect to its mitochondrial DNA (mt DNA origin

    Directory of Open Access Journals (Sweden)

    Anibal Eugênio Vercesi Filho

    2010-01-01

    Full Text Available The Zebu breeds were introduced in Brazil mainly in the last century by imports from the Indian subcontinent. When the Zebu cattle arrived, the national herd suffered a significative change by backcrossing the national cows of taurine origin with Zebu sires. These processes created a polymorphism in the mitochondrial DNA (mtDNA in the Zebu animals with are in a major part derived from backcrossing and sharing mtDNA of taurine origin. To verify the maternal origin of cows belonging to the Dairy Gyr herd of APTA, Mococa 60 females were analyzed and 33 presented mtDNA from Bos taurus origin and 27 presented mtDNA from Bos indicus origin. None of these animals presented patterns of both mtDNA origins, indicating absence of heteroplasmy for these mitochondrial genotypes.

  4. Connected Vehicle Pilot Deployment Program phase 1 : comprehensive deployment plan : New York City : volume 1 : technical application : part I : technical and management approach.

    Science.gov (United States)

    2016-08-01

    This document describes the Deployment Plan for the New York City Department of Transportation (NYC) Connected Vehicle Pilot Deployment (CVPD) Project. This plan describes the approach to complete Phase 2 Design/Build/Test, and Phase 3 Operate and Ma...

  5. Installed Cost Benchmarks and Deployment Barriers for Residential Solar Photovoltaics with Energy Storage: Q1 2016

    Energy Technology Data Exchange (ETDEWEB)

    Ardani, Kristen; O' Shaughnessy, Eric; Fu, Ran; McClurg, Chris; Huneycutt, Joshua; Margolis, Robert

    2016-12-01

    In this report, we fill a gap in the existing knowledge about PV-plus-storage system costs and value by providing detailed component- and system-level installed cost benchmarks for residential systems. We also examine other barriers to increased deployment of PV-plus-storage systems in the residential sector. The results are meant to help technology manufacturers, installers, and other stakeholders identify cost-reduction opportunities and inform decision makers about regulatory, policy, and market characteristics that impede solar plus storage deployment. In addition, our periodic cost benchmarks will document progress in cost reductions over time. To analyze costs for PV-plus-storage systems deployed in the first quarter of 2016, we adapt the National Renewable Energy Laboratory's component- and system-level cost-modeling methods for standalone PV. In general, we attempt to model best-in-class installation techniques and business operations from an installed-cost perspective. In addition to our original analysis, model development, and review of published literature, we derive inputs for our model and validate our draft results via interviews with industry and subject-matter experts. One challenge to analyzing the costs of PV-plus-storage systems is choosing an appropriate cost metric. Unlike standalone PV, energy storage lacks universally accepted cost metrics, such as dollars per watt of installed capacity and lifetime levelized cost of energy. We explain the difficulty of arriving at a standard approach for reporting storage costs and then provide the rationale for using the total installed costs of a standard PV-plus-storage system as our primary metric, rather than using a system-size-normalized metric.

  6. Real-Time PCR Quantification of Chloroplast DNA Supports DNA Barcoding of Plant Species.

    Science.gov (United States)

    Kikkawa, Hitomi S; Tsuge, Kouichiro; Sugita, Ritsuko

    2016-03-01

    Species identification from extracted DNA is sometimes needed for botanical samples. DNA quantification is required for an accurate and effective examination. If a quantitative assay provides unreliable estimates, a higher quantity of DNA than the estimated amount may be used in additional analyses to avoid failure to analyze samples from which extracting DNA is difficult. Compared with conventional methods, real-time quantitative PCR (qPCR) requires a low amount of DNA and enables quantification of dilute DNA solutions accurately. The aim of this study was to develop a qPCR assay for quantification of chloroplast DNA from taxonomically diverse plant species. An absolute quantification method was developed using primers targeting the ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit (rbcL) gene using SYBR Green I-based qPCR. The calibration curve was generated using the PCR amplicon as the template. DNA extracts from representatives of 13 plant families common in Japan. This demonstrates that qPCR analysis is an effective method for quantification of DNA from plant samples. The results of qPCR assist in the decision-making will determine the success or failure of DNA analysis, indicating the possibility of optimization of the procedure for downstream reactions.

  7. Characterization of Staphylococcus aureus Primosomal DnaD Protein: Highly Conserved C-Terminal Region Is Crucial for ssDNA and PriA Helicase Binding but Not for DnaA Protein-Binding and Self-Tetramerization.

    Directory of Open Access Journals (Sweden)

    Yen-Hua Huang

    Full Text Available The role of DnaD in the recruitment of replicative helicase has been identified. However, knowledge of the DNA, PriA, and DnaA binding mechanism of this protein for the DnaA- and PriA-directed replication primosome assemblies is limited. We characterized the DNA-binding properties of DnaD from Staphylococcus aureus (SaDnaD and analyzed its interactions with SaPriA and SaDnaA. The gel filtration chromatography analysis of purified SaDnaD and its deletion mutant proteins (SaDnaD1-195, SaDnaD1-200 and SaDnaD1-204 showed a stable tetramer in solution. This finding indicates that the C-terminal region aa 196-228 is not crucial for SaDnaD oligomerization. SaDnaD forms distinct complexes with ssDNA of different lengths. In fluorescence titrations, SaDnaD bound to ssDNA with a binding-site size of approximately 32 nt. A stable complex of SaDnaD1-195, SaDnaD1-200, and SaDnaD1-204 with ssDNA dT40 was undetectable, indicating that the C-terminal region of SaDnaD (particularly aa 205-228 is crucial for ssDNA binding. The SPR results revealed that SaDnaD1-195 can interact with SaDnaA but not with SaPriA, which may indicate that DnaD has different binding sites for PriA and DnaA. Both SaDnaD and SaDnaDY176A mutant proteins, but not SaDnaD1-195, can significantly stimulate the ATPase activity of SaPriA. Hence, the stimulation effect mainly resulted from direct contact within the protein-protein interaction, not via the DNA-protein interaction. Kinetic studies revealed that the SaDnaD-SaPriA interaction increases the Vmax of the SaPriA ATPase fivefold without significantly affecting the Km. These results indicate that the conserved C-terminal region is crucial for ssDNA and PriA helicase binding, but not for DnaA protein-binding and self-tetramerization.

  8. Recent progress on DNA based walkers.

    Science.gov (United States)

    Pan, Jing; Li, Feiran; Cha, Tae-Gon; Chen, Haorong; Choi, Jong Hyun

    2015-08-01

    DNA based synthetic molecular walkers are reminiscent of biological protein motors. They are powered by hybridization with fuel strands, environment induced conformational transitions, and covalent chemistry of oligonucleotides. Recent developments in experimental techniques enable direct observation of individual walkers with high temporal and spatial resolution. The functionalities of state-of-the-art DNA walker systems can thus be analyzed for various applications. Herein we review recent progress on DNA walker principles and characterization methods, and evaluate various aspects of their functions for future applications. Copyright © 2014 Elsevier Ltd. All rights reserved.

  9. DNA preservation in silk.

    Science.gov (United States)

    Liu, Yawen; Zheng, Zhaozhu; Gong, He; Liu, Meng; Guo, Shaozhe; Li, Gang; Wang, Xiaoqin; Kaplan, David L

    2017-06-27

    The structure of DNA is susceptible to alterations at high temperature and on changing pH, irradiation and exposure to DNase. Options to protect and preserve DNA during storage are important for applications in genetic diagnosis, identity authentication, drug development and bioresearch. In the present study, the stability of total DNA purified from human dermal fibroblast cells, as well as that of plasmid DNA, was studied in silk protein materials. The DNA/silk mixtures were stabilized on filter paper (silk/DNA + filter) or filter paper pre-coated with silk and treated with methanol (silk/DNA + PT-filter) as a route to practical utility. After air-drying and water extraction, 50-70% of the DNA and silk could be retrieved and showed a single band on electrophoretic gels. 6% silk/DNA + PT-filter samples provided improved stability in comparison with 3% silk/DNA + filter samples and DNA + filter samples for DNA preservation, with ∼40% of the band intensity remaining at 37 °C after 40 days and ∼10% after exposure to UV light for 10 hours. Quantitative analysis using the PicoGreen assay confirmed the results. The use of Tris/borate/EDTA (TBE) buffer enhanced the preservation and/or extraction of the DNA. The DNA extracted after storage maintained integrity and function based on serving as a functional template for PCR amplification of the gene for zinc finger protein 750 (ZNF750) and for transgene expression of red fluorescence protein (dsRed) in HEK293 cells. The high molecular weight and high content of a crystalline beta-sheet structure formed on the coated surfaces likely accounted for the preservation effects observed for the silk/DNA + PT-filter samples. Although similar preservation effects were also obtained for lyophilized silk/DNA samples, the rapid and simple processing available with the silk-DNA-filter membrane system makes it appealing for future applications.

  10. Force induced DNA melting

    International Nuclear Information System (INIS)

    Santosh, Mogurampelly; Maiti, Prabal K

    2009-01-01

    When pulled along the axis, double-strand DNA undergoes a large conformational change and elongates by roughly twice its initial contour length at a pulling force of about 70 pN. The transition to this highly overstretched form of DNA is very cooperative. Applying a force perpendicular to the DNA axis (unzipping), double-strand DNA can also be separated into two single-stranded DNA, this being a fundamental process in DNA replication. We study the DNA overstretching and unzipping transition using fully atomistic molecular dynamics (MD) simulations and argue that the conformational changes of double-strand DNA associated with either of the above mentioned processes can be viewed as force induced DNA melting. As the force at one end of the DNA is increased the DNA starts melting abruptly/smoothly above a critical force depending on the pulling direction. The critical force f m , at which DNA melts completely decreases as the temperature of the system is increased. The melting force in the case of unzipping is smaller compared to the melting force when the DNA is pulled along the helical axis. In the case of melting through unzipping, the double-strand separation has jumps which correspond to the different energy minima arising due to sequence of different base pairs. The fraction of Watson-Crick base pair hydrogen bond breaking as a function of force does not show smooth and continuous behavior and consists of plateaus followed by sharp jumps.

  11. Uplink scheduling and adjacent-channel coupling loss analysis for TD-LTE deployment.

    Science.gov (United States)

    Yeo, Woon-Young; Moon, Sung Ho; Kim, Jae-Hoon

    2014-01-01

    TD-LTE, one of the two duplexing modes in LTE, operates in unpaired spectrum and has the advantages of TDD-based technologies. It is expected that TD-LTE will be more rapidly deployed in near future and most of WiMax operators will upgrade their networks to TD-LTE gradually. Before completely upgrading to TD-LTE, WiMax may coexist with TD-LTE in an adjacent frequency band. In addition, multiple TD-LTE operators may deploy their networks in adjacent bands. When more than one TDD network operates in adjacent frequency bands, severe interference may happen due to adjacent channel interference (ACI) and unsynchronized operations. In this paper, coexistence issues between TD-LTE and other systems are analyzed and coexistence requirements are provided. This paper has three research objectives. First, frame synchronization between TD-LTE and WiMax is discussed by investigating possible combinations of TD-LTE and WiMax configurations. Second, an uplink scheduling algorithm is proposed to utilize a leakage pattern of ACI in synchronized operations. Third, minimum requirements for coexistence in unsynchronized operations are analyzed by introducing a concept of adjacent-channel coupling loss. From the analysis and simulation results, we can see that coexistence of TD-LTE with other TDD systems is feasible if the two networks are synchronized. For the unsynchronized case, some special cell-site engineering techniques may be required to reduce the ACI.

  12. Deployment Algorithms of Wireless Sensor Networks for Near-surface Underground Oil and Gas Pipeline Monitoring

    Directory of Open Access Journals (Sweden)

    Hua-Ping YU

    2014-07-01

    Full Text Available Oil and gas pipelines are the infrastructure of national economic development. Deployment problem of wireless underground sensor networks (WUSN for oil and gas pipeline systems is a fundamental problem. This paper firstly analyzed the wireless channel characteristics and energy consumption model in near-surface underground soil, and then studied the spatial structure of oil and gas pipelines and introduced the three-layer system structure of WUSN for oil and gas pipelines monitoring. Secondly, the optimal deployment strategy in XY plane and XZ plane which were projected from three-dimensional oil and gas pipeline structure was analyzed. Thirdly, the technical framework of using kinetic energy of the fluid in pipelines to recharge sensor nodes and partition strategy for energy consumption balance based on the wireless communication technology of magnetic induction waveguide were proposed, which can effectively improve the energy performance and connectivity of the network, and provide theoretical guidance and practical basis for the monitoring of long oil and gas pipeline network, the city tap water pipe network and sewage pipe network.

  13. DNA Open states and DNA hydratation

    International Nuclear Information System (INIS)

    Lema-Larre, B. de; Martin-Landrove, M

    1995-01-01

    It is a very well-known fact that an protonic exchange exists among natural DNA filaments and synthetic polynucleotides with the solvent (1--2). The existence of DNA open states, that is to say states for which the interior of the DNA molecule is exposed to the external environment, it has been demonstrated by means of proton-deuterium exchange (3). This work has carried out experiments measuring the dispersion of the traverse relaxation rate (4), as a pulsation rate function in a Carr-Purcell-Meiboom-Gill (CPMG) pulses sequence rate, to determine changes in the moist layer of the DNA molecule. The experiments were carried out under different experimental conditions in order to vary the probability that open states occurs, such as temperature or the exposure to electromagnetic fields. Some theoretical models were supposed to adjust the experimental results including those related to DNA non linear dynamic [es

  14. Systems and methods for modeling and analyzing networks

    Science.gov (United States)

    Hill, Colin C; Church, Bruce W; McDonagh, Paul D; Khalil, Iya G; Neyarapally, Thomas A; Pitluk, Zachary W

    2013-10-29

    The systems and methods described herein utilize a probabilistic modeling framework for reverse engineering an ensemble of causal models, from data and then forward simulating the ensemble of models to analyze and predict the behavior of the network. In certain embodiments, the systems and methods described herein include data-driven techniques for developing causal models for biological networks. Causal network models include computational representations of the causal relationships between independent variables such as a compound of interest and dependent variables such as measured DNA alterations, changes in mRNA, protein, and metabolites to phenotypic readouts of efficacy and toxicity.

  15. A fuzzy quality function deployment approach to improve a component of a supervisory control and data acquisition system

    OpenAIRE

    Cristea Ciprian; Saşa Ciprian; Cristea Maria

    2017-01-01

    Monitoring and control of electric transformer stations, frequently spread out over small or large geographical areas, are achieved with supervisory control and data acquisition (SCADA). Quality function deployment (QFD) is a valuable analyzing tool in product design and development. To solve the uncertainty or inherent imprecision in QFD, many researchers have applied the fuzzy set theory to QFD and have developed various fuzzy QFD approaches. The literature regarding applying fuzzy QFD for ...

  16. Optimization of Hydroacoustic Equipment Deployment at Foster Dam, 2013

    Energy Technology Data Exchange (ETDEWEB)

    Hughes, James S.; Johnson, Gary E.; Ploskey, Gene R.; Hennen, Matthew J.; Fischer, Eric S.; Zimmerman, Shon A.

    2013-03-01

    The goal of the study was to optimize performance of the fixed-location hydroacoustic systems at Foster Dam (FOS) by determining deployment and data acquisition methods that minimized structural, electrical, and acoustic interference. Optimization of the hydroacoustic systems will establish methodology for sampling by active acoustic methods during this year-long evaluation of juvenile salmonid passage at FOS.

  17. Financial Services and the Deployment of Agricultural Innovations in ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    As partners of farmers' associations and small agri-businesses, financial cooperatives can play an important role in the adoption of agricultural innovations by providing relevant financial services. This project will test the ability of financial services to support the deployment and large-scale adoption of innovations ...

  18. Cloud Environment Automation: from infrastructure deployment to application monitoring

    Science.gov (United States)

    Aiftimiei, C.; Costantini, A.; Bucchi, R.; Italiano, A.; Michelotto, D.; Panella, M.; Pergolesi, M.; Saletta, M.; Traldi, S.; Vistoli, C.; Zizzi, G.; Salomoni, D.

    2017-10-01

    The potential offered by the cloud paradigm is often limited by technical issues, rules and regulations. In particular, the activities related to the design and deployment of the Infrastructure as a Service (IaaS) cloud layer can be difficult to apply and time-consuming for the infrastructure maintainers. In this paper the research activity, carried out during the Open City Platform (OCP) research project [1], aimed at designing and developing an automatic tool for cloud-based IaaS deployment is presented. Open City Platform is an industrial research project funded by the Italian Ministry of University and Research (MIUR), started in 2014. It intends to research, develop and test new technological solutions open, interoperable and usable on-demand in the field of Cloud Computing, along with new sustainable organizational models that can be deployed for and adopted by the Public Administrations (PA). The presented work and the related outcomes are aimed at simplifying the deployment and maintenance of a complete IaaS cloud-based infrastructure.

  19. Supporting Children Facing the Deployment of a Parent

    Science.gov (United States)

    Rahill, Stephanie

    2013-01-01

    As the cycle of deployments to war zones by military service members and other federal government employees continue, school psychologists likely have encountered or will encounter children in their schools who have been dealing with an absence of a parent for extended periods of time. While some school psychologists who live and work near major…

  20. Real-life C-RAN deployment considerations

    DEFF Research Database (Denmark)

    Hansen, Line Maria Pyndt; Ruepp, Sarah Renée; Christiansen, Henrik Lehrmann

    2017-01-01

    procedures and best practices for roll out are yet to be established. This work provides a case study, where a small but densely populated part of the network owned by the Danish mobile network operator, TDC, is evaluated for C-RAN deployment. A roadmap is provided which uses traffic data as input...