WorldWideScience

Sample records for departmental assessment update

  1. Departmental Assessment: Productive Endeavor or Painful Encounter.

    Science.gov (United States)

    Roberts, Elizabeth A.

    The spring of 1995 brought the onus of assessment to the Department of Communication Arts at Ohio Northern University (ONU). Often seen as a painful process, departmental assessments can become productive endeavors. Although, as a private institution, ONU is not subject to the dictates for assessment from the State Board of Education, assessment…

  2. Departmental Appeals Board Decisions

    Data.gov (United States)

    U.S. Department of Health & Human Services — Decisions issued by the Chair and Board Members of the Departmental Appeals Board concerning determinations in discretionary, project grant programs, including...

  3. Physical fitness assessment: an update.

    Science.gov (United States)

    Wilder, Robert P; Greene, Jill Amanda; Winters, Kathryne L; Long, William B; Gubler, K; Edlich, Richard F

    2006-01-01

    The American College of Sports Medicine (ACSM) gives the following definition of health-related physical fitness: Physical fitness is defined as a set of attributes that people have or achieve that relates to the ability to perform physical activity. It is also characterized by (1) an ability to perform daily activities with vigor, and (2) a demonstration of traits and capacities that are associated with a low risk of premature development of hypokinetic diseases (e.g., those associated with physical inactivity). Information from an individual's health and medical records can be combined with information from physical fitness assessment to meet the specific health goals and rehabilitative needs of that individual. Attaining adequate informed consent from participants prior to exercise testing is mandatory because of ethical and legal considerations.A physical fitness assessment includes measures of body composition, cardiorespiratory endurance, muscular fitness, and musculoskeletal flexibility. The three common techniques for assessing body composition are hydrostatic weighing, and skinfold measurements, and anthropometric measurements. Cardiorespiratory endurance is a crucial component of physical fitness assessment because of its strong correlation with health and health risks. Maximal oxygen uptake (VO2max) is the traditionally accepted criterion for measuring cardiorespiratory endurance. Although maximal-effort tests must be used to measure VO2max, submaximal exercise can be used to estimate this value. Muscular fitness has historically been used to describe an individual's integrated status of muscular strength and muscular endurance. An individual's muscular strength is specific to a particular muscle or muscle group and refers to the maximal force (N or kg) that the muscle or muscle group can generate. Dynamic strength can be assessed by measuring the movement of an individual's body against an external load. Isokinetic testing may be performed by assessing

  4. Thailand : Investment Climate Assessment Update

    OpenAIRE

    World Bank

    2008-01-01

    This report provides an up-to-date assessment of the investment climate of Thailand. As the socio-economic framework in which enterprises operate including infrastructure, policies and regulations improving the investment climate is helpful for productivity and economic growth. The report is based mainly on the results of the second round of the Thailand Productivity and Investment Climate...

  5. An updated dose assessment for Rongelap Island

    Energy Technology Data Exchange (ETDEWEB)

    Robison, W.L.; Conrado, C.L.; Bogen, K.T.

    1994-07-01

    We have updated the radiological dose assessment for Rongelap Island at Rongelap Atoll using data generated from field trips to the atoll during 1986 through 1993. The data base used for this dose assessment is ten fold greater than that available for the 1982 assessment. Details of each data base are presented along with details about the methods used to calculate the dose from each exposure pathway. The doses are calculated for a resettlement date of January 1, 1995. The maximum annual effective dose is 0.26 mSv y{sup {minus}1} (26 mrem y{sup {minus}1}). The estimated 30-, 50-, and 70-y integral effective doses are 0.0059 Sv (0.59 rem), 0.0082 Sv (0.82 rem), and 0.0097 Sv (0.97 rem), respectively. More than 95% of these estimated doses are due to 137-Cesium ({sup 137}Cs). About 1.5% of the estimated dose is contributed by 90-Strontium ({sup 90}Sr), and about the same amount each by 239+240-Plutonium ({sup 239+240}PU), and 241-Americium ({sup 241}Am).

  6. Assessment of exposure of workers to ionizing radiation from radioiodine and technetium in nuclear medicine departmental facilities

    Directory of Open Access Journals (Sweden)

    Grażyna Krajewska

    2013-10-01

    Full Text Available Background: Due to its use of ionising radiation, the field of nuclear medicine is a unique and significant part of medical diagnostics and patient treatment. The aim of this study was to assess the internal exposure of nuclear medicine employees to radioiodine 131I and technetium 99mTc as well as to assess the external exposure doses. Material and Methods: The radioiodine 131I and technetium 99mTc contents in the thyroid of staff members (about 100 persons dealing with these radionuclides have been measured in four departments of nuclear medicine. The measurements were conducted with a portable detection unit for in situ measurements of radioiodine and technetium. High sensitivity environmental thermoluminescent dosimeters (TLD were used to measure the external exposure dose. Results: The average values and ranges of radioiodine 131I activity measured in the thyroids of all of the medical units' employees were: 83 Bq (range: 70-250 Bq, 280 Bq (range: 70-4000 Bq, 275 Bq (range: 70-1000 Bq for technical staff, nuclear medicine staff and hospital services staff, respectively. The mean value of technetium 99mTc content in the thyroids of nuclear medicine staff was approximately 1500 Bq (range: 50- -1800 Bq. External exposure dose rates were in the range of 0.5-10 μGy/h. Conclusions: The calculated average effective dose for particular person caused by the inhalation of radioiodine 131I is below 5% of 20 mSv/year (occupational exposure limit. Med Pr 2013;64(5:625–630

  7. Assessment of stochastically updated finite element models using reliability indicator

    Science.gov (United States)

    Hua, X. G.; Wen, Q.; Ni, Y. Q.; Chen, Z. Q.

    2017-01-01

    Finite element (FE) model updating techniques have been a viable approach to correcting an initial mathematical model based on test data. Validation of the updated FE models is usually conducted by comparing model predictions with independent test data that have not been used for model updating. This approach of model validation cannot be readily applied in the case of a stochastically updated FE model. In recognizing that structural reliability is a major decision factor throughout the lifecycle of a structure, this study investigates the use of structural reliability as a measure for assessing the quality of stochastically updated FE models. A recently developed perturbation method for stochastic FE model updating is first applied to attain the stochastically updated models by using the measured modal parameters with uncertainty. The reliability index and failure probability for predefined limit states are computed for the initial and the stochastically updated models, respectively, and are compared with those obtained from the 'true' model to assess the quality of the two models. Numerical simulation of a truss bridge is provided as an example. The simulated modal parameters involving different uncertainty magnitudes are used to update an initial model of the bridge. It is shown that the reliability index obtained from the updated model is much closer to true reliability index than that obtained from the initial model in the case of small uncertainty magnitude; in the case of large uncertainty magnitude, the reliability index computed from the initial model rather than from the updated model is closer to the true value. The present study confirms the usefulness of measurement-calibrated FE models and at the same time also highlights the importance of the uncertainty reduction in test data for reliable model updating and reliability evaluation.

  8. Departmental Excellence: Constituencies in Tension.

    Science.gov (United States)

    Arnett, Ronald C.; Fritz, Janie M. Harden

    1999-01-01

    Places the question of departmental excellence within "the winds of historicity and temporality" and the political demands of multiple constituencies. Concludes that the task for every department that wants to pursue excellence is to know, understand, and operate within the hidden curriculum of a campus that socializes faculty to the…

  9. 42 CFR 93.207 - Departmental Appeals Board or DAB.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Departmental Appeals Board or DAB. 93.207 Section 93.207 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH...

  10. Departmentality

    DEFF Research Database (Denmark)

    Harste, Gorm

    2008-01-01

      Niklas Luhmann's system theory outlines a methodology that focuses empirical problems in depth. This is possible by means of an abductive use of an overwhelmingly accessibility to theoretical observations. However, this theory is itself a result of historical developments. It origins in a path...

  11. Departmentality

    DEFF Research Database (Denmark)

    Harste, Gorm

    2008-01-01

    of self-descriptive communications studied by Luhmann as semantic transformations. The paper goes back to Immanuel Kant's theory of systems and traces its origins on the basis of an evolution of a subdifferentiated legal system. Especially the semantic differentiation of forms is followed and takes...

  12. Update earthquake risk assessment in Cairo, Egypt

    Science.gov (United States)

    Badawy, Ahmed; Korrat, Ibrahim; El-Hadidy, Mahmoud; Gaber, Hanan

    2016-12-01

    The Cairo earthquake (12 October 1992; m b = 5.8) is still and after 25 years one of the most painful events and is dug into the Egyptians memory. This is not due to the strength of the earthquake but due to the accompanied losses and damages (561 dead; 10,000 injured and 3000 families lost their homes). Nowadays, the most frequent and important question that should rise is "what if this earthquake is repeated today." In this study, we simulate the same size earthquake (12 October 1992) ground motion shaking and the consequent social-economic impacts in terms of losses and damages. Seismic hazard, earthquake catalogs, soil types, demographics, and building inventories were integrated into HAZUS-MH to produce a sound earthquake risk assessment for Cairo including economic and social losses. Generally, the earthquake risk assessment clearly indicates that "the losses and damages may be increased twice or three times" in Cairo compared to the 1992 earthquake. The earthquake risk profile reveals that five districts (Al-Sahel, El Basateen, Dar El-Salam, Gharb, and Madinat Nasr sharq) lie in high seismic risks, and three districts (Manshiyat Naser, El-Waily, and Wassat (center)) are in low seismic risk level. Moreover, the building damage estimations reflect that Gharb is the highest vulnerable district. The analysis shows that the Cairo urban area faces high risk. Deteriorating buildings and infrastructure make the city particularly vulnerable to earthquake risks. For instance, more than 90 % of the estimated buildings damages are concentrated within the most densely populated (El Basateen, Dar El-Salam, Gharb, and Madinat Nasr Gharb) districts. Moreover, about 75 % of casualties are in the same districts. Actually, an earthquake risk assessment for Cairo represents a crucial application of the HAZUS earthquake loss estimation model for risk management. Finally, for mitigation, risk reduction, and to improve the seismic performance of structures and assure life safety

  13. Update earthquake risk assessment in Cairo, Egypt

    Science.gov (United States)

    Badawy, Ahmed; Korrat, Ibrahim; El-Hadidy, Mahmoud; Gaber, Hanan

    2017-07-01

    The Cairo earthquake (12 October 1992; m b = 5.8) is still and after 25 years one of the most painful events and is dug into the Egyptians memory. This is not due to the strength of the earthquake but due to the accompanied losses and damages (561 dead; 10,000 injured and 3000 families lost their homes). Nowadays, the most frequent and important question that should rise is "what if this earthquake is repeated today." In this study, we simulate the same size earthquake (12 October 1992) ground motion shaking and the consequent social-economic impacts in terms of losses and damages. Seismic hazard, earthquake catalogs, soil types, demographics, and building inventories were integrated into HAZUS-MH to produce a sound earthquake risk assessment for Cairo including economic and social losses. Generally, the earthquake risk assessment clearly indicates that "the losses and damages may be increased twice or three times" in Cairo compared to the 1992 earthquake. The earthquake risk profile reveals that five districts (Al-Sahel, El Basateen, Dar El-Salam, Gharb, and Madinat Nasr sharq) lie in high seismic risks, and three districts (Manshiyat Naser, El-Waily, and Wassat (center)) are in low seismic risk level. Moreover, the building damage estimations reflect that Gharb is the highest vulnerable district. The analysis shows that the Cairo urban area faces high risk. Deteriorating buildings and infrastructure make the city particularly vulnerable to earthquake risks. For instance, more than 90 % of the estimated buildings damages are concentrated within the most densely populated (El Basateen, Dar El-Salam, Gharb, and Madinat Nasr Gharb) districts. Moreover, about 75 % of casualties are in the same districts. Actually, an earthquake risk assessment for Cairo represents a crucial application of the HAZUS earthquake loss estimation model for risk management. Finally, for mitigation, risk reduction, and to improve the seismic performance of structures and assure life safety

  14. 18 CFR 367.26 - Departmental classification.

    Science.gov (United States)

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Departmental classification. 367.26 Section 367.26 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... ACT General Instructions § 367.26 Departmental classification. Salaries and wages and all other...

  15. Departmental h-Index: Evidence for Publishing Less?

    Science.gov (United States)

    Tyrrell, Pascal N; Moody, Alan R; Moody, J Oscar C; Ghiam, Neda

    2017-02-01

    The h-index is an established method for determining an individual faculty member's impact on the scientific literature. The purpose of this study was to measure and describe over time the combined h-index of a large university medical imaging department. All faculty members from the Department of Medical Imaging, University of Toronto, were identified from administrative records for 6 separate years between 2000-2014. Individual members' and the departmental h-index were calculated using citation data from the Scopus database. Descriptive univariate statistics were reported. Factors contributing to the change in departmental h-index over time were assessed using linear regression analysis. The number of faculty members increased from 117 in 2000 to 186 in 2014. The departmental h-index increased from 48 in 2000 to 142 in 2014. During this time period, the median h-index for faculty members increased from 4 (interquartile range 2-8) to 10 (interquartile range 5-19). Regression analysis revealed that for every additional staff member, the departmental h-index increased by 1.4 (standard error = 0.1, P h-index of members by 1 the departmental h-index increased by 15.7 (standard error = 0.6, P h-index, it is important to foster impactful research from within the faculty ranks of the department. The h-index of academic radiology departments is a meaningful tool that allows for evaluation from within and against other academic centres. Copyright © 2016 Canadian Association of Radiologists. Published by Elsevier Inc. All rights reserved.

  16. The USGS national geothermal resource assessment: An update

    Science.gov (United States)

    Williams, C.F.; Reed, M.J.; Galanis, S.P.; DeAngelo, J.

    2007-01-01

    The U. S. Geological Survey (USGS) is working with the Department of Energy's (DOE) Geothermal Technologies Program and other geothermal organizations on a three-year effort to produce an updated assessment of available geothermal resources. The new assessment will introduce significant changes in the models for geothermal energy recovery factors, estimates of reservoir volumes, and limits to temperatures and depths for electric power production. It will also include the potential impact of evolving Enhanced Geothermal Systems (EGS) technology. An important focus in the assessment project is on the development of geothermal resource models consistent with the production histories and observed characteristics of exploited geothermal fields. New models for the recovery of heat from heterogeneous, fractured reservoirs provide a physically realistic basis for evaluating the production potential of both natural geothermal reservoirs and reservoirs that may be created through the application of EGS technology. Project investigators have also made substantial progress studying geothermal systems and the factors responsible for their formation through studies in the Great Basin-Modoc Plateau region, Coso, Long Valley, the Imperial Valley and central Alaska, Project personnel are also entering the supporting data and resulting analyses into geospatial databases that will be produced as part of the resource assessment.

  17. Departmentalization and Twenty-First Century Skills

    Science.gov (United States)

    Watts, Toy Coles

    2012-01-01

    The purpose of this study was to investigate the relationship between school organizational style and student outcomes. The research questions that guided this study were, "Is there a difference in mathematical performance of fourth graders who receive departmentalized instruction as compared to fourth grade students who receive…

  18. A Departmental Cost-Effectiveness Model.

    Science.gov (United States)

    Holleman, Thomas, Jr.

    In establishing a departmental cost-effectiveness model, the traditional cost-effectiveness model was discussed and equipped with a distant and deflation equation for both benefits and costs. Next, the economics of costing was examined and program costing procedures developed. Then, the model construct was described as it was structured around the…

  19. Non-Parametric Bayesian Updating within the Assessment of Reliability for Offshore Wind Turbine Support Structures

    DEFF Research Database (Denmark)

    Ramirez, José Rangel; Sørensen, John Dalsgaard

    2011-01-01

    This work illustrates the updating and incorporation of information in the assessment of fatigue reliability for offshore wind turbine. The new information, coming from external and condition monitoring can be used to direct updating of the stochastic variables through a non-parametric Bayesian...... updating approach and be integrated in the reliability analysis by a third-order polynomial chaos expansion approximation. Although Classical Bayesian updating approaches are often used because of its parametric formulation, non-parametric approaches are better alternatives for multi-parametric updating...... with a non-conjugating formulation. The results in this paper show the influence on the time dependent updated reliability when non-parametric and classical Bayesian approaches are used. Further, the influence on the reliability of the number of updated parameters is illustrated....

  20. Standards for the assessment of salivary glands – an update

    Science.gov (United States)

    Ochal-Choińska, Aleksandra

    2016-01-01

    The paper is an update of 2011 Standards for Ultrasound Assessment of Salivary Glands, which were developed by the Polish Ultrasound Society. We have described current ultrasound technical requirements, assessment and measurement techniques as well as guidelines for ultrasound description. We have also discussed an ultrasound image of normal salivary glands as well as the most important pathologies, such as inflammation, sialosis, collagenosis, injuries and proliferative processes, with particular emphasis on lesions indicating high risk of malignancy. In acute bacterial inflammation, the salivary glands appear as hypoechoic, enlarged or normal-sized, with increased parenchymal flow. The echogenicity is significantly increased in viral infections. Degenerative lesions may be seen in chronic inflammations. Hyperechoic deposits with acoustic shadowing can be visualized in lithiasis. Parenchymal fibrosis is a dominant feature of sialosis. Sjögren syndrome produces different pictures of salivary gland parenchymal lesions at different stages of the disease. Pleomorphic adenomas are usually hypoechoic, well-defined and polycyclic in most cases. Warthin tumor usually presents as a hypoechoic, oval-shaped lesion with anechoic cystic spaces. Malignancies are characterized by blurred outlines, irregular shape, usually heterogeneous echogenicity and pathological neovascularization. The accompanying metastatic lesions are another indicator of malignancy, however, final diagnosis should be based on biopsy findings. PMID:27446602

  1. Statewide Writing Assessment Follow-Up; Federal Reporting Requirements; Preparing the School District Assessment Portfolio. Update # 5. STARS: School-Based Teacher-Led Assessment and Reporting System.

    Science.gov (United States)

    Nebraska State Dept. of Education, Lincoln.

    This update provides information about the Nebraska Statewide Writing Assessment follow-up, the federal reporting of assessment information, and preparing the school District Assessment Portfolio. The information is intended to assist local educators in the reporting of local assessment information in June 2001. The update on the writing…

  2. Non-Parametric Bayesian Updating within the Assessment of Reliability for Offshore Wind Turbine Support Structures

    DEFF Research Database (Denmark)

    Ramirez, José Rangel; Sørensen, John Dalsgaard

    2011-01-01

    This work illustrates the updating and incorporation of information in the assessment of fatigue reliability for offshore wind turbine. The new information, coming from external and condition monitoring can be used to direct updating of the stochastic variables through a non-parametric Bayesian u...

  3. Predicting Results of the Research Excellence Framework using Departmental h-Index -- Revisited

    CERN Document Server

    Mryglod, O; Holovatch, Yu; Berche, B

    2015-01-01

    We revisit our recent study [Predicting results of the Research Excellence Framework using departmental h-index, Scientometrics, 2014, 1-16; arXiv:1411.1996] in which we attempted to predict outcomes of the UK's Research Excellence Framework (REF~2014) using the so-called departmental $h$-index. Here we report that our predictions failed to anticipate with any accuracy either overall REF outcomes or movements of individual institutions in the rankings relative to their positions in the previous Research Assessment Exercise (RAE~2008).

  4. SOA approach for integration of departmental systems.

    Science.gov (United States)

    Itälä, Timo; Ukkola, Jari; Virtanen, Aino; Mykkänen, Juha

    2008-01-01

    In this paper a unified method for integration of departmental systems into the main systems of a healthcare organization is described. The approach is based on combining Business Process Modeling (BPM) and Service Oriented Architecture (SOA) methods and technologies. A top-down approach is used for modeling the care process and supporting care services which in turn are decomposed down to such a level of granularity that they can be described and implemented as web services described with Web Services Description Language (WSDL) documents. Then a bottom-up approach is used for wrapping the existing departmental systems and their interfaces into web services using Enterprise Service Bus (ESB). Finally the orchestration of the services is described using executable Business Process Execution Language (BPEL) code.

  5. Cyprus; Financial Sector Assessment Program Update: Technical Note: Factual Update on Basel Core Principles for Effective Banking Supervision: ASDCS

    OpenAIRE

    International Monetary Fund

    2009-01-01

    This technical note presents Cyprus’s Financial Sector Assessment Program Update. The authority has worked to enhance the quality of supervision, inter alia in the organizational area, upgrading the number of staff and staff expertise, and planning to intensify onsite supervision. A single supervisor for all banks operating in Cyprus could enhance the effectiveness and efficiency of supervision and could support the creation of a level playing for all banks.

  6. A Computer-Aided Bibliometrics System for Journal Citation Analysis and Departmental Core Journal Ranking List Generation

    Directory of Open Access Journals (Sweden)

    Yih-Chearng Shiue

    2004-12-01

    Full Text Available Due to the tremendous increase and variation in serial publications, faculties in department of university are finding it difficult to generate and update their departmental core journal list regularly and accurately, and libraries are finding it difficult to maintain their current serial collection for different departments. Therefore, the evaluation of a departmental core journal list is an important task for departmental faculties and librarians. A departmental core journal list not only helps departments understand research performances of faculties and students, but also helps librarians make decisions about which journals to retain and which to cancel. In this study, a Computer-Aided Bibliometrics System was implemented and two methodologies (JCDF and LibJF were proposed in order to generate a departmental core journal ranking list and make the journal citation analysis. Six departments were taken as examples, with MIS as the major one. One journal citation pattern was found and the ratio of Turning point-to-No. journal was always around 0.07 among the 10 journals and 6 departments. After comparing with four methodologies via overlapping rate and standard deviation distances, the two proposed methodologies were shown to be better than questionnaire and library subscription method.

  7. Calculation and Updating of Reliability Parameters in Probabilistic Safety Assessment

    Science.gov (United States)

    Zubair, Muhammad; Zhang, Zhijian; Khan, Salah Ud Din

    2011-02-01

    The internal events of nuclear power plant are complex and include equipment maintenance, equipment damage etc. These events will affect the probability of the current risk level of the system as well as the reliability of the equipment parameter values so such kind of events will serve as an important basis for systematic analysis and calculation. This paper presents a method for reliability parameters calculation and their updating. The method is based on binomial likelihood function and its conjugate beta distribution. For update parameters Bayes' theorem has been selected. To implement proposed method a computer base program is designed which provide help to estimate reliability parameters.

  8. An Update on the Alaska Statewide Testing Program. Assessment Reports 8-10.

    Science.gov (United States)

    Alaska State Dept. of Education, Juneau, Office of Education, Assessment and Research.

    The Alaska Statewide Assessment Test (ASAT) in reading and math is administered to fourth and eighth graders every two years. This document contains three separate assessment reports generally titled "An Update on the Alaska Statewide Testing Program." Assessment Report 8, "The Interpretive Panels Look at Results," lists…

  9. 76 FR 64098 - Order of Succession for the Office of Departmental Operations and Coordination

    Science.gov (United States)

    2011-10-17

    ... URBAN DEVELOPMENT Order of Succession for the Office of Departmental Operations and Coordination AGENCY: Office of Departmental Operations and Coordination, HUD. ACTION: Notice of order of succession. SUMMARY: In this notice, the Director, Office of Departmental Operations and Coordination, Department...

  10. Annual Pension Fund Update

    CERN Multimedia

    Pension Fund

    2011-01-01

    All members and beneficiaries of the Pension Fund are invited to attend the Annual Pension Fund Update to be held in the CERN Council Chamber on Tuesday 20 September 2011 from 10-00 to 12-00 a.m. Copies of the 2010 Financial Statements are available from departmental secretariats. Coffee and croissants will be served prior to the meeting as of 9-30 a.m.

  11. 41 CFR 114-51.100 - Departmental Quarters Handbook.

    Science.gov (United States)

    2010-07-01

    ... Handbook. 114-51.100 Section 114-51.100 Public Contracts and Property Management Federal Property...-General § 114-51.100 Departmental Quarters Handbook. The Office of Acquisition and Property Management (PAM) has prepared the Departmental Quarters Handbook (DQH), 400 DM, which provides detailed guidelines...

  12. 28 CFR 0.32 - Applicability of existing departmental regulations.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Applicability of existing departmental regulations. 0.32 Section 0.32 Judicial Administration DEPARTMENT OF JUSTICE ORGANIZATION OF THE DEPARTMENT OF JUSTICE Community Relations Service § 0.32 Applicability of existing departmental...

  13. 17 CFR 256.01-6 - Departmental classification required.

    Science.gov (United States)

    2010-04-01

    ... (CONTINUED) UNIFORM SYSTEM OF ACCOUNTS FOR MUTUAL SERVICE COMPANIES AND SUBSIDIARY SERVICE COMPANIES, PUBLIC UTILITY HOLDING COMPANY ACT OF 1935 General Instructions § 256.01-6 Departmental classification required... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Departmental...

  14. 75 FR 53951 - Fisheries of the Gulf of Mexico; Southeast Data, Assessment, and Review (SEDAR) Update; Greater...

    Science.gov (United States)

    2010-09-02

    ... Assessment Conference Call for Gulf of Mexico greater amberjack. SUMMARY: The SEDAR update of the assessment... National Oceanic and Atmospheric Administration RIN 0648-XY63 Fisheries of the Gulf of Mexico; Southeast Data, Assessment, and Review (SEDAR) Update; Greater Amberjack AGENCY: National Marine Fisheries...

  15. 75 FR 51982 - Fisheries of the Gulf of Mexico; Southeast Data, Assessment, and Review (SEDAR) Update; Greater...

    Science.gov (United States)

    2010-08-24

    ... Assessment Webinars. SUMMARY: The SEDAR update of the assessment of the Gulf of Mexico stock of greater... National Oceanic and Atmospheric Administration RIN 0648-XY34 Fisheries of the Gulf of Mexico; Southeast Data, Assessment, and Review (SEDAR) Update; Greater Amberjack AGENCY: National Marine Fisheries...

  16. Enterprise imaging and multi-departmental PACS

    Energy Technology Data Exchange (ETDEWEB)

    Bergh, Bjoern [Universitaetsklinikum Heidelberg, Director of Information Technology and Medical Engineering, Heidelberg (Germany)

    2006-12-15

    The aim of this review is to present the status of digital image acquisition and archiving outside of radiology and to describe the technical concepts and possibilities of how a ''radiology'' Picture Archiving and Communication System (PACS) can become a multi-departmental (MD-)PACS. First the principles of system integration technology are explained and illustrated by the description of a typical radiology system integration. Then four types of modality integration approaches are defined: the direct modality integration (Type-I), the integration via DICOM acquisition software (Type-II) the integration via specialised systems either with (Type-III) or without PACS connection (Type-IV). The last section is dedicated to the presentation of the PACS requirements of selected interdisciplinary modality types [Endoscopy, Ultrasound and Electrocardiography (ECG)] and clinical disciplines (Pathology, Dermatology, Ophthalmology and Cardiology), which are then compared with the technical possibilities of a MD-PACS. (orig.)

  17. 75 FR 35442 - Fisheries of the Gulf of Mexico; Southeast Data, Assessment, and Review (SEDAR) Update; Greater...

    Science.gov (United States)

    2010-06-22

    ... Data, Assessment, and Review (SEDAR) Update; Greater Amberjack. AGENCY: National Marine Fisheries... and Gulf States Marine Fisheries Commissions have implemented the Southeast Data, Assessment and.... Participants include data collectors and database managers; stock assessment scientists, biologists, and...

  18. MO-DE-304-00: Workforce Assessment Committee Update

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2015-06-15

    The Abt study of medical physicist work values for radiation oncology physics services, Round IV is completed. It supersedes the Abt III study of 2008. The 2015 Abt study measured qualified medical physicist (QMP) work associated with routine radiation oncology procedures as well as some special procedures. As before, a work model was created to allow the medical physicist to defend QMP work based on both routine and special procedures service mix. The work model can be used to develop a cost justification report for setting charges for radiation oncology physics services. The Abt study Round IV was designed to empower the medical physicist to negotiate a service or employment contract with providers based on measured national QMP workforce and staffing data. For a variety of reasons, the diagnostic imaging contingent of AAPM has had a more difficult time trying estimate workforce requirements than their therapy counterparts. Over the past several years, the Diagnostic Work and Workforce Study Subcommittee (DWWSS) has collected survey data from AAPM members, but the data have been very difficult to interpret. The DWWSS has reached out to include more AAPM volunteers to create a more full and accurate representation of actual clinical practice models on the subcommittee. Though much work remains, through hours of discussion and brainstorming, the DWWSS has somewhat of a clear path forward. This talk will provide attendees with an update on the efforts of the subcommittee. Learning Objectives: Understand the new information documented in the Abt studies. Understand how to use the Abt studies to justify medical physicist staffing. Learn relevant historical information on imaging physicist workforce. Understand the process of the DWWSS in 2014. Understand the intended path forward for the DWWSS.

  19. Future of America's Forests and Rangelands: Update to the 2010 Resources Planning Act Assessment

    Science.gov (United States)

    Forest Service U.S. Department of Agriculture

    2016-01-01

    The Update to the 2010 Resources Planning Act (RPA) Assessment summarizes findings about the status, trends, and projected future of forests, rangelands, wildlife, biodiversity, water, outdoor recreation, and urban forests, as well as the effects of climate change upon these resources. Varying assumptions about population and economic growth, land use change, and...

  20. Ductal carcinoma in situ - update on risk assessment and management.

    Science.gov (United States)

    Pang, Jia-Min B; Gorringe, Kylie L; Fox, Stephen B

    2016-01-01

    Ductal carcinoma in situ (DCIS) accounts for ~20-25% of breast cancers. While DCIS is not life-threatening, it may progress to invasive carcinoma over time, and treatment intended to prevent invasive progression may itself cause significant morbidity. Accurate risk assessment is therefore necessary to avoid over- or undertreatment of an individual patient. In this review we will outline the evidence for current management of DCIS, discuss approaches to DCIS risk assessment and challenges facing identification of novel DCIS biomarkers.

  1. An update on the assessment of osteoporosis using radiologic techniques

    Energy Technology Data Exchange (ETDEWEB)

    Damilakis, John; Maris, Thomas G. [University of Crete, Department of Medical Physics, Faculty of Medicine, P.O. Box 2208, Iraklion, Crete (Greece); Karantanas, Apostolos H. [University of Crete, Department of Radiology, Faculty of Medicine, P.O. Box 2208, Iraklion, Crete (Greece)

    2007-06-15

    In this article, the currently available radiologic techniques for assessing osteoporosis are reviewed. Density measurements of the skeleton using dual X-ray absorptiometry (DXA) are clinically indicated for the assessment of osteoporosis and for the evaluation of therapies. DXA is the most widely used technique for identifying patients with osteoporosis. Quantitative computed tomography (QCT) is the only method, which provides a volumetric density. Unlike DXA, QCT allows for selective trabecular measurement and is less sensitive to degenerative diseases of the spine. The analysis of bone structure in conjunction with bone density is an exciting new field in the assessment of osteoporosis. High-resolution multi-slice CT and micro-CT are useful tools for the assessment of bone microarchitecture. A growing literature indicates that quantitative ultrasound (QUS) techniques are capable of assessing fracture risk. Although the ease of use and the absence of ionizing radiation make QUS attractive, the specific role of QUS techniques in clinical practice needs further determination. Considerable progress has been made in the development of MR techniques for assessing osteoporosis during the last few years. In addition to relaxometry techniques, high-resolution MR imaging, diffusion MR imaging and in-vivo MR spectroscopy may be used to quantify trabecular bone architecture and mineral composition. (orig.)

  2. Curriculum structure, content, learning and assessment in European undergraduate dental education - update 2010.

    LENUS (Irish Health Repository)

    Manogue, M

    2011-08-01

    This paper presents an updated statement on behalf of the Association for Dental Education in Europe (ADEE) in relation to proposals for undergraduate Curriculum Structure, Content, Learning, Assessment and Student \\/ Staff Exchange for dental education in Europe. A task force was constituted to consider these issues and the two previous, related publications produced by the Association (Plasschaert et al 2006 and 2007) were revised. The broad European dental community was circulated and contributed to the revisions. The paper was approved at the General Assembly of ADEE, held in Amsterdam in August 2010 and will be updated again in 2015.

  3. 22 CFR 161.6 - Responsibilities of departmental officials.

    Science.gov (United States)

    2010-04-01

    ... Secretary for Congressional Relations in the preparation of environmental documents relating to legislation....6 Section 161.6 Foreign Relations DEPARTMENT OF STATE ENVIRONMENTAL PROTECTION REGULATIONS FOR IMPLEMENTATION OF THE NATIONAL ENVIRONMENTAL POLICY ACT (NEPA) NEPA and Departmental Decisionmaking §...

  4. Dyslipidemia therapy update: the importance of full lipid profile assessment.

    LENUS (Irish Health Repository)

    Menown, I B A

    2009-07-01

    Lipid guidelines typically focus on total cholesterol +\\/- low-density lipoprotein cholesterol levels with less emphasis on high-density lipoprotein cholesterol (HDL-C) or triglyceride assessment, thus potentially underestimating cardiovascular (CV) risk and the need for lifestyle or treatment optimization. In this article, we highlight how reliance on isolated total cholesterol assessment may miss prognostically relevant lipid abnormalities; we describe from the European Systematic COronary Risk Evaluation (SCORE) data set how incorporation of HDL-C may improve estimation of CV risk; and, finally, we critically evaluate the evidence base surrounding triglycerides and CV risk.

  5. Dental caries: an updated medical model of risk assessment.

    Science.gov (United States)

    Kutsch, V Kim

    2014-04-01

    Dental caries is a transmissible, complex biofilm disease that creates prolonged periods of low pH in the mouth, resulting in a net mineral loss from the teeth. Historically, the disease model for dental caries consisted of mutans streptococci and Lactobacillus species, and the dental profession focused on restoring the lesions/damage from the disease by using a surgical model. The current recommendation is to implement a risk-assessment-based medical model called CAMBRA (caries management by risk assessment) to diagnose and treat dental caries. Unfortunately, many of the suggestions of CAMBRA have been overly complicated and confusing for clinicians. The risk of caries, however, is usually related to just a few common factors, and these factors result in common patterns of disease. This article examines the biofilm model of dental caries, identifies the common disease patterns, and discusses their targeted therapeutic strategies to make CAMBRA more easily adaptable for the privately practicing professional.

  6. Pain assessment and measurement in neonates: an updated review.

    Science.gov (United States)

    Cong, Xiaomei; McGrath, Jacqueline M; Cusson, Regina M; Zhang, Di

    2013-12-01

    Pain assessment and measurement are the cornerstones of pain management. Pain assessment connotes a comprehensive multidimensional description. Conversely, pain measurement provides a numeric quantitative description of each factor illustrating pain qualities. Pain scales provide a composite score used to guide practice and research. The type of infant pain instrument chosen is a significant factor in guiding pain management practice. The purpose of this review was to summarize current infant pain measures by introducing a conceptual framework for pain measurement. Although more than 40 infant pain instruments exist, many were devised solely for research purposes; several of the newly developed instruments largely overlap with existing instruments. Integration of pain management into daily practice remains problematic. Understanding how each instrument measures infant pain allows clinicians to make better decisions about what instrument to use with which infant and in what circumstances. In addition, novel new measurement techniques need further testing.

  7. White paper updating conclusions of 1998 ILAW performance assessment

    Energy Technology Data Exchange (ETDEWEB)

    MANN, F.M.

    2000-05-11

    The purpose of this document is to provide a comparison of the estimated immobilized low-activity waste (LAW) disposal system performance against established performance objectives using the beat estimates for parameters and models to describe the system. The principal advances in knowledge since the last performance assessment (known as the 1998 ILAW PA [Mann 1998a]) have been in site specific information and data on the waste form performance for BNFL, Inc. relevant glass formulations. The white paper also estimates the maximum release rates for technetium and other key radionuclides and chemicals from the waste form. Finally, this white paper provides limited information on the impact of changes in waste form loading.

  8. Mexico; Financial Sector Assessment Program Update: Technical Note: Industrial Organization and Competition: Pension System in Mexico

    OpenAIRE

    International Monetary Fund

    2007-01-01

    The technical note on Mexico’s Financial Sector Assessment Program update analyzes that the private pension system’s regulator in Mexico has introduced innovate rules. Mexico, as with many other countries in Latin America, has adopted an individual capitalization pension system. The design of these pension reforms confers the administration of pension funds to private companies. Under these schemes, competition plays a key role, keeping prices low, a good quality of service, and an effici...

  9. Update of Market Assessment for Capturing Water Conservation Opportunities in the Federal Sector

    Energy Technology Data Exchange (ETDEWEB)

    Mcmordie, Katherine; Solana, Amy E.; Elliott, Douglas B.; Sullivan, Gregory P.; Parker, Graham B.

    2005-09-08

    This updated market assessment for capturing water conservation opportunities in the Federal sector is based on a new analytical approach that utilizes newly available data and technologies. The new approach fine-tunes the original assessment by using actual Federal water use, which is now tracked by DOE (as compared to using estimated water use). Federal building inventory data is also used to disseminate water use by end-use technology in the Federal sector. In addition, this analysis also examines the current issues and obstacles that face performance contracting of water efficiency projects at Federal sites.

  10. Assessing and updating the reliability of concrete bridges subjected to spatial deterioration - principles and software implementation

    DEFF Research Database (Denmark)

    Schneider, Ronald; Fischer, Johannes; Bügler, Maximilian

    2015-01-01

    . The overall system reliability is computed by means of a probabilistic structural model coupled with the deterioration model. Inspection data are included in the system reliability calculation through Bayesian updating on the basis of the DBN model. As proof of concept, a software prototype is developed...... to implement the method presented here. The software prototype is applied to a typical highway bridge and the influence of inspection information on the system deterioration state and the structural reliability is quantified taking into account the spatial correlation of the corrosion process. This work...... is a step towards developing a software tool that can be used by engineering practitioners to perform reliability assessments of ageing concrete bridges and update their reliability with inspection and monitoring data....

  11. Engineered materials characterization report, volume 3 - corrosion data and modeling update for viability assessments

    Energy Technology Data Exchange (ETDEWEB)

    McCright, R D

    1998-06-30

    This Engineered Materials Characterization Report (EMCR), Volume 3, discusses in considerable detail the work of the past 18 months on testing the candidate materials proposed for the waste-package (WP) container and on modeling the performance of those materials in the Yucca Mountain (YM) repository setting This report was prepared as an update of information and serves as one of the supporting documents to the Viability Assessment (VA) of the Yucca Mountain Project. Previous versions of the EMCR have provided a history and background of container-materials selection and evaluation (Volume I), a compilation of physical and mechanical properties for the WP design effort (Volume 2), and corrosion-test data and performance-modeling activities (Volume 3). Because the information in Volumes 1 and 2 is still largely current, those volumes are not being revised. As new information becomes available in the testing and modeling efforts, Volume 3 is periodically updated to include that information.

  12. 75 FR 47265 - Fisheries of the Gulf of Mexico; Southeast Data, Assessment, and Review (SEDAR) update; greater...

    Science.gov (United States)

    2010-08-05

    ... Assessment Webinar I for Gulf of Mexico greater amberjack. SUMMARY: The SEDAR update of the assessment of the Gulf of Mexico stock of greater amberjack will consist of a series of webinars. This assessment will... National Oceanic and Atmospheric Administration RIN: 0648-XX99 Fisheries of the Gulf of Mexico; Southeast...

  13. Assessment Update: Progress, Trends, and Practices in Higher Education. Volume 25, Issue 5, September-October 2013

    Science.gov (United States)

    Banta, Trudy W., Ed.

    2013-01-01

    This issue of "Assessment Update" presents the following articles: (1) Through the Rearview Looking Glass: Collaborative Writing and the Accreditation Self-Study; (2) Editor's Notes: Another Glimpse of Evaluation in China; (3) Assessment Is Not a Spectator Sport: Experiencing Authentic Assessment in the Classroom; (4) Faculty Development…

  14. 18 CFR 16.14 - Departmental recommendation for takeover.

    Science.gov (United States)

    2010-04-01

    ... recommendation for takeover. 16.14 Section 16.14 Conservation of Power and Water Resources FEDERAL ENERGY... 15 of the Federal Power Act § 16.14 Departmental recommendation for takeover. (a) A Federal department or agency may file a recommendation that the United States exercise its right to take over...

  15. 31 CFR Appendix A to Subpart A of... - Departmental Offices

    Science.gov (United States)

    2010-07-01

    ... Offices 1. In general. This appendix applies to the Departmental Offices as defined in 31 CFR 1.1(a)(1). 2.... Requests for records. Initial determinations under 31 CFR 1.5(h) as to whether to grant requests for... to deny records. (i) Appellate determinations under 31 CFR 1.5(i) with respect to records of...

  16. Teaching Graduate and Undergraduate Research Methods: A Multipronged Departmental Initiative

    Science.gov (United States)

    Shostak, Sara; Girouard, Jennifer; Cunningham, David; Cadge, Wendy

    2010-01-01

    This article describes a departmental initiative designed to integrate the teaching of graduate and undergraduate sociology through research methodology and the completion of actual research projects. The goal was to develop a multilevel team approach within which faculty, graduate students, and undergraduates would view their work as part of a…

  17. Elementary School Organization: Self-Contained and Departmentalized Classroom Structures.

    Science.gov (United States)

    Des Moines Public Schools, IA.

    Surveys were conducted to investigate contemporary thought regarding organizational practices at the elementary level, with particular attention to identifying the extent to which departmentalization was supported by research and actually employed in 24 elementary schools in the Midwest and in 41 Des Moines elementary schools. Four committees…

  18. Pre-Service Teachers' Perceptions of Departmentalization of Elementary Schools

    Science.gov (United States)

    Liu, Fuchang

    2011-01-01

    This paper discusses the advantages and disadvantages of departmentalization of elementary schools, with an emphasis on teaching mathematics, as perceived by preservice teachers who shared their opinions through online discussion. Advantages include teachers' enthusiasm about and focused attention on the specialized area and students' easier…

  19. 75 FR 20977 - Departmental Management; Advisory Committee on Minority Farmers

    Science.gov (United States)

    2010-04-22

    ... maximizing the participation of minority farmers and ranchers in USDA programs; and (3) civil rights... organizations with a history of working with minority farmers and ranchers; (3) not less than two civil rights...; ] DEPARTMENT OF AGRICULTURE Departmental Management; Advisory Committee on Minority Farmers AGENCY:...

  20. Departmental Differences in Student Perceptions of 'Ideal' Teaching.

    Science.gov (United States)

    Kaufman, Brian J.

    Departmental differences in student perceptions of teaching effectiveness were measured using behaviorally anchored rating scales (BARS). The 495 college students were taking junior and senior level courses in art, business, computer science, French, psychology, and sociology. Each subject completed either the BARS or a simple summated scale, both…

  1. Faculty Agency: Departmental Contexts That Matter in Faculty Careers

    Science.gov (United States)

    Campbell, Corbin M.; O'Meara, KerryAnn

    2014-01-01

    In a modern context of constrained resources and high demands, faculty exert agency to strategically navigate their careers (Baez 2000a; Neumann et al. 2006). Guided by the O'Meara et al. (2011) framework on agency in faculty professional lives, this study used Structural Equation Modeling to investigate which departmental factors…

  2. Updating the biomedical engineering curriculum: Inclusion of Health Technology Assessment subjects.

    Science.gov (United States)

    Martinez Licona, Fabiola; Urbina, Edmundo Gerardo; Azpiroz-Leehan, Joaquin

    2010-01-01

    This paper describes the work being carried out at Metropolitan Autonomous University (UAM) in Mexico City with regard to the continuous evaluation and updating of the Biomedical Engineering (BME) curriculum. In particular the courses regarded as part of the BME basic branch are reduced and new sets of elective subjects are proposed in order to bring closer the research work at UAM with the subjects in the BME curriculum. Special emphasis is placed on subjects dealing with Health Technology Assessment (HTA) and Health economics, as this branch of the BME discipline is quite promising in Mexico, but there are very few professionals in the field with adequate qualifications.

  3. An update on childhood bone health: mineral accrual, assessment and treatment.

    Science.gov (United States)

    Sopher, Aviva B; Fennoy, Ilene; Oberfield, Sharon E

    2015-02-01

    To update the reader's knowledge about the factors that influence bone mineral accrual and to review the advances in the assessment of bone health and treatment of bone disorders. Maternal vitamin D status influences neonatal calcium levels, bone mineral density (BMD) and bone size. In turn, BMD z-score tends to track in childhood. These factors highlight the importance of bone health as early as fetal life. Dual-energy x-ray absorptiometry is the mainstay of clinical bone health assessment in this population because of the availability of appropriate reference data. Recently, more information has become available about the assessment and treatment of bone disease in chronically ill pediatric patients. Bone health must become a health focus starting prenatally in order to maximize peak bone mass and to prevent osteoporosis-related bone disease in adulthood. Vitamin D, calcium and weight-bearing activity are the factors of key importance throughout childhood in achieving optimal bone health as BMD z-score tracks through childhood and into adulthood. Recent updates of the International Society for Clinical Densitometry focus on the appropriate use of dual-energy x-ray absorptiometry in children of all ages, including children with chronic disease, and on the treatment of pediatric bone disease.

  4. Project SAFE. Update of the SFR-1 safety assessment. Phase 1

    Energy Technology Data Exchange (ETDEWEB)

    Andersson, Johan [ed.] [Golder Associates AB (Sweden); Riggare, P. [ed.] [Swedish Nuclear Fuel and Waste Management Co., Stockholm (Sweden); Skagius, K. [ed.] [Kemakta Konsult AB, Stockholm (Sweden)

    1998-10-01

    SFR-1 is a facility for disposal of low-level radioactive operational waste from the nuclear power plants in Sweden. Low-level radioactive waste from industry, medicine, and research is also disposed in SFR-1. The facility is situated in bedrock beneath the Baltic Sea, 1 km off the coast near the Forsmark nuclear power plant. SFR-1 was built between the years 1983 and 1988. An assessment of the long-term performance of the facility was included in the vast documentation that was a part of the application for an operational license. The assessment was presented in the form of a final safety report. In the operational licence for SFR-1 it is stated that renewed safety assessments should be carried out at least each ten years. In order to meet this demand SKB has launched a special project, SAFE (Safety Assessment of Final Disposal of Operational Radioactive Waste). The aim of the project is to update the safety analysis and to prepare a safety report that will be presented to the Swedish authorities not later than year 2000. Project SAFE is divided into three phases. The first phase is a prestudy, and the results of the prestudy are given in this report. The aim of the prestudy is to identify issues where additional studies would improve the basis for the updated safety analysis as well as to suggest how these studies should be carried out. The work has been divided into six different topics, namely the inventory, the near field, the far field, the biosphere, radionuclide transport calculations and scenarios. For each topic the former safety reports and regulatory reviews are scrutinised and needs for additional work is identified. The evaluations are given in appendices covering the respective topics. The main report is a summary of the appendices with a more stringent description of the repository system and the processes that are of interest and therefore should be addressed in an updated safety assessment. However, it should be pointed out that one of the

  5. Forest Resources of the United States, 2012: a technical document supporting the Forest Service 2010 update of the RPA Assessment

    Science.gov (United States)

    Sonja N. Oswalt; W. Brad Smith; Patrick D. Miles; Scott A. Pugh

    2014-01-01

    Forest resource statistics from the 2010 Resources Planning Act (RPA) Assessment were updated to provide current information on the Nation's forests as a baseline for the 2015 national assessment. Resource tables present estimates of forest area, volume, mortality, growth, removals, and timber products output in various ways, such as by ownership, region, or State...

  6. Interventions for rosacea: abridged updated Cochrane systematic review including GRADE assessments.

    Science.gov (United States)

    van Zuuren, E J; Fedorowicz, Z

    2015-09-01

    Rosacea is a common chronic facial dermatosis. This update of our Cochrane review on interventions for rosacea summarizes the evidence, including Grading of Recommendations Assessment, Development and Evaluation (GRADE) Working Group assessments, of the effects of the currently available treatments. Searches included the following: Cochrane Skin Group Specialised Register, CENTRAL in The Cochrane Library, MEDLINE, EMBASE, LILACS and the Science Citation Index, and ongoing trials registries (July 2014). We included 106 randomized controlled trials (RCTs) with 13 631 participants, a more than 80% increase since the last update in 2011. Pooling of data was feasible for a few outcomes, for topical metronidazole and azelaic acid and both appeared to be more effective than placebo (moderate and high-quality evidence, respectively). Topical ivermectin was more effective than placebo based on two studies (high-quality evidence), and slightly more effective than metronidazole in one study. Brimonidine was more effective than vehicle in reducing erythema in rosacea (high-quality evidence). Ciclosporin ophthalmic emulsion was effective for ocular rosacea (low-quality evidence). For oral treatments there was moderate-quality evidence for the effectiveness of tetracycline based on two old studies, and high-quality evidence for doxycycline 40 mg compared with placebo according to physician assessments. One study at high risk of bias demonstrated equivalent effectiveness for azithromycin and doxycycline 100 mg. Minocycline 45 mg may be effective for papulopustular rosacea (low-quality evidence). Low-dose isotretinoin appeared to be slightly more effective than doxycycline 50-100 mg (high-quality evidence). Laser and light-based therapies for erythema in rosacea were effective (low-quality evidence). Further RCTs are required for ocular rosacea.

  7. Bayesian updating in a fault tree model for shipwreck risk assessment.

    Science.gov (United States)

    Landquist, H; Rosén, L; Lindhe, A; Norberg, T; Hassellöv, I-M

    2017-03-14

    Shipwrecks containing oil and other hazardous substances have been deteriorating on the seabeds of the world for many years and are threatening to pollute the marine environment. The status of the wrecks and the potential volume of harmful substances present in the wrecks are affected by a multitude of uncertainties. Each shipwreck poses a unique threat, the nature of which is determined by the structural status of the wreck and possible damage resulting from hazardous activities that could potentially cause a discharge. Decision support is required to ensure the efficiency of the prioritisation process and the allocation of resources required to carry out risk mitigation measures. Whilst risk assessments can provide the requisite decision support, comprehensive methods that take into account key uncertainties related to shipwrecks are limited. The aim of this paper was to develop a method for estimating the probability of discharge of hazardous substances from shipwrecks. The method is based on Bayesian updating of generic information on the hazards posed by different activities in the surroundings of the wreck, with information on site-specific and wreck-specific conditions in a fault tree model. Bayesian updating is performed using Monte Carlo simulations for estimating the probability of a discharge of hazardous substances and formal handling of intrinsic uncertainties. An example application involving two wrecks located off the Swedish coast is presented. Results show the estimated probability of opening, discharge and volume of the discharge for the two wrecks and illustrate the capability of the model to provide decision support. Together with consequence estimations of a discharge of hazardous substances, the suggested model enables comprehensive and probabilistic risk assessments of shipwrecks to be made.

  8. Update of a thermodynamic database for radionuclides to assist solubility limits calculation for performance assessment

    Energy Technology Data Exchange (ETDEWEB)

    Duro, L.; Grive, M.; Cera, E.; Domenech, C.; Bruno, J. (Enviros Spain S.L., Barcelona (ES))

    2006-12-15

    This report presents and documents the thermodynamic database used in the assessment of the radionuclide solubility limits within the SR-Can Exercise. It is a supporting report to the solubility assessment. Thermodynamic data are reviewed for 20 radioelements from Groups A and B, lanthanides and actinides. The development of this database is partially based on the one prepared by PSI and NAGRA. Several changes, updates and checks for internal consistency and completeness to the reference NAGRA-PSI 01/01 database have been conducted when needed. These modifications are mainly related to the information from the various experimental programmes and scientific literature available until the end of 2003. Some of the discussions also refer to a previous database selection conducted by Enviros Spain on behalf of ANDRA, where the reader can find additional information. When possible, in order to optimize the robustness of the database, the description of the solubility of the different radionuclides calculated by using the reported thermodynamic database is tested in front of experimental data available in the open scientific literature. When necessary, different procedures to estimate gaps in the database have been followed, especially accounting for temperature corrections. All the methodologies followed are discussed in the main text

  9. An updated assessment of the prospects for fuel cell-powered cars. An information paper

    Energy Technology Data Exchange (ETDEWEB)

    Sanderson, T.K. [Future Energy Solutions, Harwell (United Kingdom)

    2005-07-01

    This report presents updated conclusions of the Department of Trade and Industry's research and development programme to assess the commercial prospects for advanced fuel cells in the car market. The programme has focussed on low temperature solid polymer fuel cells (SPFCs) for transport and combined heat and power (CHP)/distributed power and high temperature solid oxide fuel cells (SOFCs) for CHP/distributed power. The report provides an assessment of the status of technology development for different types of fuel cells in terms of applications to cars and offers estimates of market potential. Some fuel-cell powered cars are now available for demonstration purposes but the report concludes that truly commercial sales are unlikely to start before 2010 and widespread deployment is expected to take a further ten years after that. The issue of fuel choice is considered largely resolved with most car manufacturers currently focussing on hydrogen as a fuel. A discussion of the prospects and barriers for fuel cell cars concludes that cost reduction is now the major barrier to the successful commercialisation of fuel cells in cars. More demonstration prototypes and field trials are required to provide information on energy, environmental and economic performance of fuel cell cars. Field trials could also provide information to assist the development of refuelling systems, fuel storage systems, stacks and other system components and to gain experience of building integrated fuel cell systems within the constraints imposed by cars.

  10. Updating a Taxonomy of Assessment Domains for staff and students: modernising it to enhance academic practice and student learning.

    OpenAIRE

    Smith, SV

    2016-01-01

    Summary of Session: The session will outline the process and rationale that our University academic working group used to update and modernise a Taxonomy of Assessment Domains and showcase our interactive tool for students and staff. Format: Short discussion paper (25 minutes) Session Learning Outcomes By the end of this session, delegates will be able to: 1.Understand how an institution- specific Taxonomy of Assessment Domains can be used to support curriculum design, outcomes based assessme...

  11. An updated assessment of the prospects for fuel cell-powered buses. An information paper

    Energy Technology Data Exchange (ETDEWEB)

    Sanderson, T.K. [Future Energy Solutions, Harwell (United Kingdom)

    2005-07-01

    This report presents updated conclusions of the Department of Trade and Industry's research and development programme to assess the commercial prospects for advanced fuel cells in buses. The programme has focussed on low temperature solid polymer fuel cells (SPFCs) for transport and combined heat and power (CHP)/distributed power and high temperature solid oxide fuel cells (SOFCs) for CHP/distributed power. As well as assessing the prospects for SPFCs in buses, the report examines those for alkaline fuel cells (AFCs) and phosphoric acid fuel cells (PAFCs) in buses. The report provides an assessment of the status of technology development for different types of fuel cells in terms of applications to buses and offers estimates of market potential. Some fuel-cell powered buses are now available for demonstration purposes but the report concludes that truly commercial sales are unlikely to start before 2010 and widespread deployment is expected to take a further ten years after that. Buses have now slipped behind cars in terms of worldwide deployment. The issue of fuel choice is considered largely resolved with most fleet vehicle/bus manufacturers currently focussing on hydrogen as a fuel. A discussion of the prospects and barriers for fuel cell buses concludes that cost reduction is now the major barrier to the successful commercialisation of fuel cells in buses. More demonstration prototypes and field trials are required to provide information on energy, environmental and economic performance of fuel cell buses. Field trials could also provide information to assist the development of refuelling systems, fuel storage systems, stacks and other system components and to gain experience of building integrated fuel cell systems.

  12. RELAP-7 Software Verification and Validation Plan - Requirements Traceability Matrix (RTM) Part 2: Code Assessment Strategy, Procedure, and RTM Update

    Energy Technology Data Exchange (ETDEWEB)

    Yoo, Jun Soo [Idaho National Lab. (INL), Idaho Falls, ID (United States); Choi, Yong Joon [Idaho National Lab. (INL), Idaho Falls, ID (United States); Smith, Curtis Lee [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-09-01

    This document addresses two subjects involved with the RELAP-7 Software Verification and Validation Plan (SVVP): (i) the principles and plan to assure the independence of RELAP-7 assessment through the code development process, and (ii) the work performed to establish the RELAP-7 assessment plan, i.e., the assessment strategy, literature review, and identification of RELAP-7 requirements. Then, the Requirements Traceability Matrices (RTMs) proposed in previous document (INL-EXT-15-36684) are updated. These RTMs provide an efficient way to evaluate the RELAP-7 development status as well as the maturity of RELAP-7 assessment through the development process.

  13. Reliability data update using condition monitoring and prognostics in probabilistic safety assessment

    Directory of Open Access Journals (Sweden)

    Hyeonmin Kim

    2015-03-01

    Full Text Available Probabilistic safety assessment (PSA has had a significant role in quantitative decision-making by finding design and operational vulnerabilities and evaluating cost-benefit in improving such weak points. In particular, it has been widely used as the core methodology for risk-informed applications (RIAs. Even though the nature of PSA seeks realistic results, there are still “conservative” aspects. One of the sources for the conservatism is the assumptions of safety analysis and the estimation of failure frequency. Surveillance, diagnosis, and prognosis (SDP, utilizing massive databases and information technology, is worth highlighting in terms of its capability for alleviating the conservatism in conventional PSA. This article provides enabling techniques to solidify a method to provide time- and condition-dependent risks by integrating a conventional PSA model with condition monitoring and prognostics techniques. We will discuss how to integrate the results with frequency of initiating events (IEs and probability of basic events (BEs. Two illustrative examples will be introduced: (1 how the failure probability of a passive system can be evaluated under different plant conditions and (2 how the IE frequency for a steam generator tube rupture (SGTR can be updated in terms of operating time. We expect that the proposed model can take a role of annunciator to show the variation of core damage frequency (CDF depending on operational conditions.

  14. Reliability data update using condition monitoring and prognostics in probabilistic safety assessment

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hyeon Min; Lee, Sang Hwan; Park, Jun Seok; Kim, Hyung Dae; Chang, Yoon Suk; Heo, Gyun Young [Dept. of Nuclear Engineering, Kyung Hee University, Yongin (Korea, Republic of)

    2015-03-15

    Probabilistic safety assessment (PSA) has had a significant role in quantitative decision making by finding design and operational vulnerabilities and evaluating cost-benefit in improving such weak points. In particular, it has been widely used as the core methodology for risk-informed applications (RIAs). Even though the nature of PSA seeks realistic results, there are still 'conservative' aspects. One of the sources for the conservatism is the assumptions of safety analysis and the estimation of failure frequency. Surveillance, diagnosis, and prognosis (SDP), utilizing massive databases and information technology, is worth highlighting in terms of its capability for alleviating the conservatism in conventional PSA. This article provides enabling techniques to solidify a method to provide time and condition-dependent risks by integrating a conventional PSA model with condition monitoring and prognostics techniques. We will discuss how to integrate the results with frequency of initiating events (IEs) and probability of basic events (BEs). Two illustrative examples will be introduced: (1) how the failure probability of a passive system can be evaluated under different plant conditions and (2) how the IE frequency for a steam generator tube rupture (SGTR) can be updated in terms of operating time. We expect that the proposed model can take a role of annunciator to show the variation of core damage frequency (CDF) depending on operational conditions.

  15. Noncarcinogenic effects of chromium: Update to health-assessment document. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Victery, W.; Lee, S.D.; Mushak, P.; Piscator, M.

    1990-04-01

    The document updates the 1984 Health Assessment Document for Chromium by addressing issues regarding noncarcinogenic health effects of chromium: oxidation states and persistence of these states in the environment, sampling and analytical methodology to differentiate these oxidation states and amounts at submicrogram ambient air levels, the degree of human exposure to chromium in the environment, both short-term and long-term, in vivo reduction of Cr (VI) to Cr (III), and effects from environmentally relevant levels on pulmonary function and renal function. Trivalent chromium is chemically stable; Cr (VI) is readily reduced to Cr (III). Oxidation state of chromium in ambient air depends on proximity to sources emitting one form over the other. Reliable monitoring methods to speciate oxidation states at ambient air levels below 1 microgram/cu m are not available. Ambient levels of total chromium (obtained from EPA's National Air Data Branch) range from a high of 0.6 microgram/cu m to below the detection limit of 0.005 microgram/cu m. Reduction of hexavalent chromium in vivo occurs in several organ systems and therefore, small amounts of inhaled Cr (VI) will be reduced before systemic absorption can occur. Trivalent chromium is an essential trace metal which potentiates actions of insulin-mediated glucose transport.

  16. Predicting Results of the Research Excellence Framework using departmental h-Index

    CERN Document Server

    Mryglod, Olesya; Holovatch, Yurij; Berche, Bertrand

    2014-01-01

    We compare estimates for past institutional research performances coming from two bibliometric indicators to the results of the UK's Research Assessment Exercise which last took place in 2008. We demonstrate that a version of the departmental h-index is better correlated with the actual results of that peer-review exercise than a competing metric known as the normalised citation-based indicator. We then determine the corresponding h-indices for 2008-2013, the period examined in the UK's Research Excellence Framework (REF) 2014. We place herewith the resulting predictions on the arXiv in advance of the REF results being published (December 2014). These may be considered as unbiased predictions of relative performances in that exercise. We will revisit this paper after the REF results are available and comment on the reliability or otherwise of these bibliometrics as compared with peer review.

  17. 76 FR 64098 - Delegation of Authority for the Office of Departmental Operations and Coordination

    Science.gov (United States)

    2011-10-17

    ... notice, the Secretary delegates to the Director of Departmental Operations and Coordination authority and.... SUPPLEMENTARY INFORMATION: Section A. Authority Delegated The Secretary hereby delegates to the Director of... URBAN DEVELOPMENT Delegation of Authority for the Office of Departmental Operations and Coordination...

  18. 22 CFR 161.12 - Environmental effects abroad of major departmental actions.

    Science.gov (United States)

    2010-04-01

    ... analysis shall be prepared in accordance with separate Departmental procedures (Foreign Affairs Manual... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Environmental effects abroad of major departmental actions. 161.12 Section 161.12 Foreign Relations DEPARTMENT OF STATE ENVIRONMENTAL PROTECTION...

  19. Average Tenure of Academic Department Heads: The Effects of Paradigm, Size, and Departmental Demography.

    Science.gov (United States)

    Pfeffer, Jeffrey; Moore, William L.

    1980-01-01

    The average tenure of academic department heads was found to be positively related to the level of paradigm development characterizing the department, negatively related to departmental size, and related to interactions of the level of paradigm development with the seniority mix of the faculty and with the departmental size. (Author/IRT)

  20. Elementary Teachers' Experiences and Perceptions of Departmentalized Instruction: A Case Study

    Science.gov (United States)

    Strohl, Alecia; Schmertzing, Lorraine; Schmertzing, Richard

    2014-01-01

    This case study investigated elementary teachers' experiences and perceptions during a trial year of departmentalized instruction in a rural south Georgia elementary school. To inform their decision about whole-school departmentalization for the future, school administrators appointed twelve first through third grade teachers to pilot the…

  1. Risk management of undesirable substances in feed following updated risk assessments

    Energy Technology Data Exchange (ETDEWEB)

    Verstraete, Frans, E-mail: Frans.Verstraete@ec.europa.eu

    2013-08-01

    Directive 2002/32/EC of 7 May 2002 of the European Parliament and of the Council on undesirable substances in animal feed is the framework for the EU action on undesirable substances in feed. This framework Directive provides: ⁎that products intended for animal feed may enter for use in the Union from third countries, be put into circulation and/or used in the Union only if they are sound, genuine and of merchantable quality and therefore when correctly used do not represent any danger to human health, animal health or to the environment or could adversely affect livestock production. ⁎that in order to protect animal and public health and the environment, maximum levels for specific undesirable substances shall be established where necessary. ⁎for mandatory consultation of a scientific body (EFSA) for all provisions which may have an effect upon public health or animal health or on the environment. ⁎that products intended for animal feed containing levels of an undesirable substance that exceed the established maximum level may not be mixed for dilution purposes with the same, or other, products intended for animal feed and may not be used for the production of compound feed. Based on the provisions and principles laid down in this framework Directive, maximum levels for a whole range of undesirable substances have been established at EU level. During the discussions in view of the adoption of Directive 2002/32/EC, the European Commission made the commitment to review all existing provisions on undesirable substances on the basis of updated scientific risk assessments. Following requests of the European Commission, the Panel on Contaminants in the Food Chain (CONTAM) from the European Food Safety Authority (EFSA) has completed a series of 30 risk assessments undertaken over the last 5 years on undesirable substances in animal feed reviewing the possible risks for animal and human health due to the presence of these substances in animal feed. EU legislation

  2. Assessment of critical minerals: Updated application of an early-warning screening methodology

    Science.gov (United States)

    McCullough, Erin; Nassar, Nedal

    2017-01-01

    Increasing reliance on non-renewable mineral resources reinforces the need for identifying potential supply constraints before they occur. The US National Science and Technology Council recently released a report that outlines a methodology for screening potentially critical minerals based on three indicators: supply risk (R), production growth (G), and market dynamics (M). This early-warning screening was initially applied to 78 minerals across the years 1996 to 2013 and identified a subset of minerals as “potentially critical” based on the geometric average of these indicators—designated as criticality potential (C). In this study, the screening methodology has been updated to include data for 2014, as well as to incorporate revisions and modifications to the data, where applicable. Overall, C declined in 2014 for the majority of minerals examined largely due to decreases in production concentration and price volatility. However, the results vary considerably across minerals, with some minerals, such as gallium, recording increases for all three indicators. In addition to assessing magnitudinal changes, this analysis also examines the significance of the change relative to historical variation for each mineral. For example, although mined nickel’s R declined modestly in 2014 in comparison to that of other minerals, it was by far the largest annual change recorded for mined nickel across all years examined and is attributable to Indonesia’s ban on the export of unprocessed minerals. Based on the 2014 results, 20 minerals with the highest C values have been identified for further study including the rare earths, gallium, germanium, rhodium, tantalum, and tungsten.

  3. U.S. States and Territories National Tsunami Hazard Assessment: Historical record and sources for waves – Update

    Science.gov (United States)

    Dunbar, Paula K.; Weaver, Craig S.

    2015-01-01

    The first U.S. Tsunami Hazard Assessment (Dunbar and Weaver, 2008) was prepared at the request of the National Tsunami Hazard Mitigation Program (NTHMP). The NTHMP is a partnership formed between federal and state agencies to reduce the impact of tsunamis through hazard assessment, warning guidance, and mitigation. The assessment was conducted in response to a 2005 joint report by the Sub-Committee on Disaster Reduction and the U.S. Group on Earth Observations entitled Tsunami Risk Reduction for the United States: A Framework for Action. The first specific action called for in the Framework was to “develop standardized and coordinated tsunami hazard and risk assessments for all coastal regions of the United States and its territories.” Since the first assessment, there have been a number of very significant tsunamis, including the 2009 Samoa, 2010 Chile, and 2011 Japan tsunamis. As a result, the NTHMP requested an update of the U.S. tsunami hazard assessment.

  4. The evolution of mobile apps for asthma: an updated systematic assessment of content and tools.

    Science.gov (United States)

    Huckvale, Kit; Morrison, Cecily; Ouyang, Jing; Ghaghda, Aseem; Car, Josip

    2015-03-23

    Interest in mobile apps that support long-term conditions such as asthma is matched by recognition of the importance of the quality and safety of apps intended for patient use. We assessed how changes over a 2-year period affected the clinical suitability of apps providing self-management information and tools for people with asthma by updating a review first performed in 2011. Systematic content assessment of all apps for iOS and Android examining the comprehensiveness of asthma information, consistency with the evidence base for asthma self-management and adherence to best practice principles for trustworthy content, comparing the quality of apps available in 2011 to those released since. Between 2011 and 2013, numbers of asthma apps more than doubled from 93 to 191, despite withdrawal of 25% (n = 23/93) of existing apps. Newer apps were no more likely than those available in 2011 to include comprehensive information, such as the use of action plans, or offer guidance consistent with evidence; 13% (n = 19/147) of all apps, and 39% (n = 9/23) of those intended to manage acute asthma, recommended self-care procedures unsupported by evidence. Despite increases in the numbers of apps targeting specific skills, such as acute asthma management (n = 12 to 23) and inhaler technique (from n = 2 to 12), the proportion consistent with guidelines (17%, n = 4/23) and inhaler instructions (25%, n = 3/12), respectively, was low, and most apps provided only either basic information about asthma (50%, n = 75/147) or simple diary functions (24%, n = 36/147). In addition to persisting questions about clinical quality and safety, dynamic aspects of app turnover and feature evolution affect the suitability of asthma apps for use in routine care. The findings underline the need for coordinated quality assurance processes that can adapt to changing clinical and information governance-related risks, ensure compliance with the evidence base and reflect

  5. Expansion of the prognostic assessment of patients with chronic obstructive pulmonary disease: the updated BODE index and the ADO index.

    Science.gov (United States)

    Puhan, Milo A; Garcia-Aymerich, Judith; Frey, Martin; ter Riet, Gerben; Antó, Josep M; Agustí, Alvar G; Gómez, Federico P; Rodríguez-Roisín, Roberto; Moons, Karel G M; Kessels, Alphons G; Held, Ulrike

    2009-08-29

    The BODE index (including body-mass index, airflow obstruction, dyspnoea, and exercise capacity) was an important contribution to the prognostic assessment of patients with chronic obstructive pulmonary disease (COPD). However, no study has assessed whether the risk of mortality predicted by the BODE index matches the observed mortality in different populations. We assessed the calibration of the BODE index, updated it to improve its calibration, and developed and validated a simplified index for use in primary-care settings. We included 232 patients from the Swiss Barmelweid cohort with longstanding and severe COPD and 342 patients from the Spanish Phenotype and Course of COPD cohort study who had had their first hospital admission due to moderate-to-severe COPD. In both cohorts we compared the observed 3-year risk of all-cause mortality with the risk predicted by the BODE index. We then updated the BODE index and developed a simplified ADO index (including age, dyspnoea, and airflow obstruction) from the Swiss cohort, and validated both in the Spanish cohort. Calibration of the BODE index was poor, with relative underprediction of 3-year risk of mortality by 36% in the Swiss cohort (median predicted risk 21.7% [IQR 12.7-31.7] vs 34.1% observed risk; p=0.013) and relative overprediction by 39% in the Spanish cohort (16.7% [12.7-31.7] vs 12.0%; p=0.035). The 3-year risk of mortality predicted by both the updated BODE (median 10.7% [8.1-13.8]) and ADO indices (11.8% [9.1-14.3]) matched the observed mortality in the Spanish cohort well (p=0.99 and p=0.98, respectively). Both the updated BODE and ADO indices could lend support to the prognostic assessment of patients with COPD in specialised and primary-care settings. Such assessment enhances the targeting of treatments to individual patients. Swiss National Science Foundation; Klinik Barmelweid; Fondo de Investigación Sanitaria Ministry of Health, Spain; Agència d'Avaluació de Tecnologia i Recerca M

  6. An official American Thoracic Society statement: update on the mechanisms, assessment, and management of dyspnea.

    Science.gov (United States)

    Parshall, Mark B; Schwartzstein, Richard M; Adams, Lewis; Banzett, Robert B; Manning, Harold L; Bourbeau, Jean; Calverley, Peter M; Gift, Audrey G; Harver, Andrew; Lareau, Suzanne C; Mahler, Donald A; Meek, Paula M; O'Donnell, Denis E

    2012-02-15

    Dyspnea is a common, distressing symptom of cardiopulmonary and neuromuscular diseases. Since the ATS published a consensus statement on dyspnea in 1999, there has been enormous growth in knowledge about the neurophysiology of dyspnea and increasing interest in dyspnea as a patient-reported outcome. The purpose of this document is to update the 1999 ATS Consensus Statement on dyspnea. An interdisciplinary committee of experts representing ATS assemblies on Nursing, Clinical Problems, Sleep and Respiratory Neurobiology, Pulmonary Rehabilitation, and Behavioral Science determined the overall scope of this update through group consensus. Focused literature reviews in key topic areas were conducted by committee members with relevant expertise. The final content of this statement was agreed upon by all members. Progress has been made in clarifying mechanisms underlying several qualitatively and mechanistically distinct breathing sensations. Brain imaging studies have consistently shown dyspnea stimuli to be correlated with activation of cortico-limbic areas involved with interoception and nociception. Endogenous and exogenous opioids may modulate perception of dyspnea. Instruments for measuring dyspnea are often poorly characterized; a framework is proposed for more consistent identification of measurement domains. Progress in treatment of dyspnea has not matched progress in elucidating underlying mechanisms. There is a critical need for interdisciplinary translational research to connect dyspnea mechanisms with clinical treatment and to validate dyspnea measures as patient-reported outcomes for clinical trials.

  7. Updated Life-Cycle Assessment of Aluminum Production and Semi-fabrication for the GREET Model

    Energy Technology Data Exchange (ETDEWEB)

    Dai, Qiang [Argonne National Lab. (ANL), Argonne, IL (United States); Kelly, Jarod C. [Argonne National Lab. (ANL), Argonne, IL (United States); Burnham, Andrew [Argonne National Lab. (ANL), Argonne, IL (United States); Elgowainy, Amgad [Argonne National Lab. (ANL), Argonne, IL (United States)

    2015-09-01

    This report serves as an update for the life-cycle analysis (LCA) of aluminum production based on the most recent data representing the state-of-the-art of the industry in North America. The 2013 Aluminum Association (AA) LCA report on the environmental footprint of semifinished aluminum products in North America provides the basis for the update (The Aluminum Association, 2013). The scope of this study covers primary aluminum production, secondary aluminum production, as well as aluminum semi-fabrication processes including hot rolling, cold rolling, extrusion and shape casting. This report focuses on energy consumptions, material inputs and criteria air pollutant emissions for each process from the cradle-to-gate of aluminum, which starts from bauxite extraction, and ends with manufacturing of semi-fabricated aluminum products. The life-cycle inventory (LCI) tables compiled are to be incorporated into the vehicle cycle model of Argonne National Laboratory’s Greenhouse Gases, Regulated Emissions, and Energy Use in Transportation (GREET) Model for the release of its 2015 version.

  8. BASELINE PARAMETER UPDATE FOR HUMAN HEALTH INPUT AND TRANSFER FACTORS FOR RADIOLOGICAL PERFORMANCE ASSESSMENTS AT THE SAVANNAH RIVER SITE

    Energy Technology Data Exchange (ETDEWEB)

    Coffield, T; Patricia Lee, P

    2007-01-31

    The purpose of this report is to update parameters utilized in Human Health Exposure calculations and Bioaccumulation Transfer Factors utilized at SRS for Performance Assessment modeling. The reason for the update is to utilize more recent information issued, validate information currently used and correct minor inconsistencies between modeling efforts performed in SRS contiguous areas of the heavy industrialized central site usage areas called the General Separations Area (GSA). SRS parameters utilized were compared to a number of other DOE facilities and generic national/global references to establish relevance of the parameters selected and/or verify the regional differences of the southeast USA. The parameters selected were specifically chosen to be expected values along with identifying a range for these values versus the overly conservative specification of parameters for estimating an annual dose to the maximum exposed individual (MEI). The end uses are to establish a standardized source for these parameters that is up to date with existing data and maintain it via review of any future issued national references to evaluate the need for changes as new information is released. These reviews are to be added to this document by revision.

  9. An Update of the Analytical Groundwater Modeling to Assess Water Resource Impacts at the Afton Solar Energy Zone

    Energy Technology Data Exchange (ETDEWEB)

    Quinn, John J. [Argonne National Lab. (ANL), Argonne, IL (United States); Greer, Christopher B. [Argonne National Lab. (ANL), Argonne, IL (United States); Carr, Adrianne E. [Argonne National Lab. (ANL), Argonne, IL (United States)

    2014-10-01

    The purpose of this study is to update a one-dimensional analytical groundwater flow model to examine the influence of potential groundwater withdrawal in support of utility-scale solar energy development at the Afton Solar Energy Zone (SEZ) as a part of the Bureau of Land Management’s (BLM’s) Solar Energy Program. This report describes the modeling for assessing the drawdown associated with SEZ groundwater pumping rates for a 20-year duration considering three categories of water demand (high, medium, and low) based on technology-specific considerations. The 2012 modeling effort published in the Final Programmatic Environmental Impact Statement for Solar Energy Development in Six Southwestern States (Solar PEIS; BLM and DOE 2012) has been refined based on additional information described below in an expanded hydrogeologic discussion.

  10. Assessment of the 60 km Rapid Update Cycle (RUC) with Near Real-Time Aircraft Reports

    Science.gov (United States)

    Cole, R. E.; Richard, C.; Kim, S.; Bailey, D.

    1998-01-01

    The National Aeronautics and Space Administration (NASA) is developing the Center-TRA-CON Advisory System (CTAS), a set of Air Traffic Management (ATM) Decision Support Tools (DST) for en route (Center) and terminal (TRACON) airspace designed to enable controllers to increase capacity and flight efficiency. A crucial component of the CTAS, or any ATM DST, is the computation of the time-of-flight of aircraft along flight path segments. Earlier NASA studies show that accurate knowledge of the wind through which the aircraft are flying is required to estimate time-of-flight accurately. There are current envisioned to be two sources of wind data for CTAS: The Rapid Update Cycle (RUC) for the Center airspace, a numerical model developed by the National Oceanic and Atmospheric Administration (NOAA) Forecast System Laboratory (FSL) and run operationally by the National Weather Service (NWS) National Center for Environmental Prediction (NCEP); and The Integrated Terminal Weather System (ITWS) Terminal Winds (TW) for the TRACON airspace, developed at MIT Lincoln Laboratory under funding from the Federal Aviation Administration (FAA). This study has three goals: (1) determine the errors in the baseline 60 km resolution RUC forecast wind fields relative to the needs of en route DSTs such as CTAS, (2) determine the benefit of using the TW algorithm to refine the RUC forecast wind fields with near real-time Meteorological Data Collection and Reporting System (MDCRS) reports, and (3) identify factors that influence wind errors in order to improve accuracy and estimate errors in real time.

  11. National assessment of hurricane-induced coastal erosion hazards—Gulf of Mexico update

    Science.gov (United States)

    Doran, Kara; Stockdon, Hilary F.; Thompson, David M.; Birchler, Justin; Plant, Nathaniel G.; Overbeck, Jacquelyn R.

    2016-01-01

    These data sets contain information on the probabilities of hurricane-induced erosion (collision, inundation and overwash) for each 1-km section of the Gulf of Mexico coast for category 1-5 hurricanes. The analysis is based on a storm-impact scaling model that uses observations of beach morphology combined with sophisticated hydrodynamic models to predict how the coast will respond to the direct landfall of category 1-5 hurricanes. Hurricane-induced water levels, due to both surge and waves, are compared to beach and dune elevations to determine the probabilities of three types of coastal change: collision (dune erosion), overwash, and inundation. Data on dune morphology (dune crest and toe elevation) and hydrodynamics (storm surge, wave setup and runup) are also included in this data set. As new beach morphology observations and storm predictions become available, this analysis will be updated to describe how coastal vulnerability to storms will vary in the future. The data presented here include the dune morphology observations, as derived from lidar surveys. For further information regarding data collection and/or processing methods refer to USGS Open-File Report 2012–1084 (http://pubs.usgs.gov/of/2012/1084/).

  12. Departmentalization and Organizational Context: The Experience of the University of Guadalajara

    Directory of Open Access Journals (Sweden)

    Adrián Acosta Silva

    2005-05-01

    Full Text Available This work consists of an evaluation of the experience of organizational reform and academic departmentalization at a Mexican public university, the University of Guadalajara (U. of G., occurred in the period of 1994-2005. It is a research carried out from the perspective of the institutional change analysis, which obeys the interest of carrying out a rigorous evaluation of the process, after 11 years of its institutional operation. From a reconstruction of the context that gave origin and sense to the reform proposal and to the idea of academic departmentalization, some of the results and conditions in which the academic departments of the U. of G operate are analyzed. Finally, some of the problems and challenges that face the departmental structure in this institutional experience are identified.

  13. An update on risk factors for cartilage loss in knee osteoarthritis assessed using MRI-based semiquantitative grading methods

    Energy Technology Data Exchange (ETDEWEB)

    Alizai, Hamza [Boston University School of Medicine, Quantitative Imaging Center, Department of Radiology, Boston, MA (United States); Aspetar Orthopaedic and Sports Medicine Hospital, Doha (Qatar); University of Texas Health Science Center at San Antonio, Department of Radiology, San Antonio, TX (United States); Roemer, Frank W. [Boston University School of Medicine, Quantitative Imaging Center, Department of Radiology, Boston, MA (United States); Aspetar Orthopaedic and Sports Medicine Hospital, Doha (Qatar); University of Erlangen-Nuremberg, Department of Radiology, Erlangen (Germany); Hayashi, Daichi [Boston University School of Medicine, Quantitative Imaging Center, Department of Radiology, Boston, MA (United States); Aspetar Orthopaedic and Sports Medicine Hospital, Doha (Qatar); Yale University School of Medicine, Department of Radiology, Bridgeport Hospital, Bridgeport, CT (United States); Crema, Michel D. [Boston University School of Medicine, Quantitative Imaging Center, Department of Radiology, Boston, MA (United States); Aspetar Orthopaedic and Sports Medicine Hospital, Doha (Qatar); Hospital do Coracao and Teleimagem, Department of Radiology, Sao Paulo (Brazil); Felson, David T. [Boston University School of Medicine, Clinical Epidemiology Research and Training Unit, Boston, MA (United States); Guermazi, Ali [Boston University School of Medicine, Quantitative Imaging Center, Department of Radiology, Boston, MA (United States); Aspetar Orthopaedic and Sports Medicine Hospital, Doha (Qatar); Boston Medical Center, Boston, MA (United States)

    2014-11-07

    Arthroscopy-based semiquantitative scoring systems such as Outerbridge and Noyes' scores were the first to be developed for the purpose of grading cartilage defects. As magnetic resonance imaging (MRI) became available faor evaluation of the osteoarthritic knee joint, these systems were adapted for use with MRI. Later on, grading methods such as the Whole Organ Magnetic Resonance Score, the Boston-Leeds Osteoarthritis Knee Score and the MRI Osteoarthritis Knee Score were designed specifically for performing whole-organ assessment of the knee joint structures, including cartilage. Cartilage grades on MRI obtained with these scoring systems represent optimal outcome measures for longitudinal studies, and are designed to enhance understanding of the knee osteoarthritis disease process. The purpose of this narrative review is to describe cartilage assessment in knee osteoarthritis using currently available MRI-based semiquantitative whole-organ scoring systems, and to provide an update on the risk factors for cartilage loss in knee osteoarthritis as assessed with these scoring systems. (orig.)

  14. Managerial span of control: a pilot study comparing departmental complexity and number of direct reports.

    Science.gov (United States)

    Merrill, Katreena Collette; Pepper, Ginette; Blegen, Mary

    2013-09-01

    Nurse managers play pivotal roles in hospitals. However, restructuring has resulted in nurse managers having wider span of control and reduced visibility. The purpose of this pilot study was to compare two methods of measuring span of control: departmental complexity and number of direct reports. Forty-one nurse managers across nine hospitals completed The Ottawa Hospital Clinical Manager Span of Control Tool (TOH-SOC) and a demographic survey. A moderate positive relationship between number of direct reports and departmental complexity score was identified (r=.49, p=managers' responsibility. Copyright © 2013 Longwoods Publishing.

  15. Departmental role and scope in infection control: use of a template that meets Joint Commission requirements.

    Science.gov (United States)

    Pearson, A; Becker, L; Almaraz, J

    1996-02-01

    Since its inception in 1990, departmental role and scope in the infection control program have developed into the five important aspects currently defined by the Joint Commission. Each health care worker needs to understand his or her role in infection prevention and control, integrate it into daily activities, and articulate this role to others. This strategy for complying with Joint Commission standards meets customer needs and can easily be adapted for use in other medical centers. The process of defining departmental roles in the infection control program will continue to evolve with increased awareness of customer needs and emphasis on continuous quality improvement.

  16. Genesis Solar Wind Collector Cleaning Assessment: Update on 60336 Sample Case Study

    Science.gov (United States)

    Goreva, Y. S.; Allums, K. K.; Gonzalez, C. P.; Jurewicz, A. J.; Burnett, D. S.; Allton, J. H.; Kuhlman, K. R.; Woolum, D.

    2015-01-01

    To maximize the scientific return of Genesis Solar Wind return mission it is necessary to characterize and remove a crash-derived particle and thin film surface contamination. A small subset of Genesis mission collector fragments are being subjected to extensive study via various techniques. Here we present an update on the sample 60336, a Czochralski silicon (Si-CZ) based wafer from the bulk array (B/C). This sample has undergone multiple cleaning steps (see the table below): UPW spin wash, aggressive chemical cleanings (including aqua regia, hot xylene and RCA1), as well as optical and chemical (EDS, ToF-SIMS) imaging. Contamination appeared on the surface of 60336 after the initial 2007 UPW cleaning. Aqua regia and hot xylene treatment (8/13/2013) did little to remove contaminants. The sample was UPW cleaned for the third time and imaged (9/16/13). The UPW removed the dark stains that were visible on the sample. However, some features, like "the Flounder" (a large, 100 micron feature in Fig. 1b) appeared largely intact, resisting all previous cleaning efforts. These features were likely from mobilized adhesive, derived from the Post-It notes used to stabilize samples for transport from Utah after the hard landing. To remove this contamination, an RCA step 1 organic cleaning (RCA1) was employed. Although we are still uncertain on the nature of the Flounder and why it is resistant to UPW and aqua regia/hot xylene treatment, we have found RCA1 to be suitable for its removal. It is likely that the glue from sticky pads used during collector recovery may have been a source for resistant organic contamination [9]; however [8] shows that UPW reaction with crash-derived organic contamination does not make particle removal more difficult.

  17. An Updated Methodology for Enhancing Risk Monitors with Integrated Equipment Condition Assessment

    Energy Technology Data Exchange (ETDEWEB)

    Ramuhalli, Pradeep [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Hirt, Evelyn H. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Coles, Garill A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Bonebrake, Christopher A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Ivans, William J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Wootan, David W. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Mitchell, Mark R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2014-07-18

    Small modular reactors (SMRs) generally include reactors with electric output of ~350 MWe or less (this cutoff varies somewhat but is substantially less than full-size plant output of 700 MWe or more). Advanced SMRs (AdvSMRs) refer to a specific class of SMRs and are based on modularization of advanced reactor concepts. Enhancing affordability of AdvSMRs will be critical to ensuring wider deployment, as AdvSMRs suffer from loss of economies of scale inherent in small reactors when compared to large (~greater than 600 MWe output) reactors and the controllable day-to-day costs of AdvSMRs will be dominated by operation and maintenance (O&M) costs. Technologies that help characterize real-time risk are important for controlling O&M costs. Risk monitors are used in current nuclear power plants to provide a point-in-time estimate of the system risk given the current plant configuration (e.g., equipment availability, operational regime, and environmental conditions). However, current risk monitors are unable to support the capability requirements listed above as they do not take into account plant-specific normal, abnormal, and deteriorating states of active components and systems. This report documents technology developments towards enhancing risk monitors that, if integrated with supervisory plant control systems, can provide the capability requirements listed and meet the goals of controlling O&M costs. The report describes research results on augmenting an initial methodology for enhanced risk monitors that integrate real-time information about equipment condition and POF into risk monitors. Methods to propagate uncertainty through the enhanced risk monitor are evaluated. Available data to quantify the level of uncertainty and the POF of key components are examined for their relevance, and a status update of this data evaluation is described. Finally, we describe potential targets for developing new risk metrics that may be useful for studying trade-offs for economic

  18. 42 CFR 498.80 - Right to request Departmental Appeals Board review of Administrative Law Judge's decision or...

    Science.gov (United States)

    2010-10-01

    ... Appeals Board Review § 498.80 Right to request Departmental Appeals Board review of Administrative Law... 42 Public Health 5 2010-10-01 2010-10-01 false Right to request Departmental Appeals Board review of Administrative Law Judge's decision or dismissal. 498.80 Section 498.80 Public Health CENTERS...

  19. Eleventh annual Department of Energy low-level waste management conference. Volume 1: Regulatory updates, performance assessment, understanding remedial action efforts

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1989-11-01

    Eighteen papers are presented in this volume. The section on regulatory updates present papers on EPA, NRC, and DOE regulations. The performance assessment section presents studies on disposal facilities at ORNL, Hanford, and the Feed Materials Production Center. The remedial action section papers discuss programs and remedial action activities. Papers have been processed separately for inclusion on the data base.

  20. Update to hazard assessment of selenium contamination at Benton Lake National Wildlife Refuge

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report summarizes a study done to assess selenium levels on Benton Lake NWR. Water was sampled for dissolved selenium in Lake Creek at the point where it enters...

  1. National assessment of shoreline change—Summary statistics for updated vector shorelines and associated shoreline change data for the Gulf of Mexico and Southeast Atlantic coasts

    Science.gov (United States)

    Himmelstoss, Emily A.; Kratzmann, Meredith G.; Thieler, E. Robert

    2017-07-18

    Long-term rates of shoreline change for the Gulf of Mexico and Southeast Atlantic regions of the United States have been updated as part of the U.S. Geological Survey’s National Assessment of Shoreline Change project. Additional shoreline position data were used to compute rates where the previous rate-of-change assessment only included four shoreline positions at a given location. The long-term shoreline change rates also incorporate the proxy-datum bias correction to account for the unidirectional onshore bias of the proxy-based high water line shorelines relative to the datum-based mean high water shorelines. The calculation of uncertainty associated with the long-term average rates has also been updated to match refined methods used in other study regions of the National Assessment project. The average rates reported here have a reduced amount of uncertainty relative to those presented in the previous assessments for these two regions.

  2. Implementing Common Core State Standards and Assessments: A Workbook for State and District Leaders. Updated

    Science.gov (United States)

    Harris, Alex; Rodriguez, Nick

    2012-01-01

    Achieve and the U.S. Education Delivery Institute have developed a practical Common Core Implementation Workbook for all states in the Partnership for Assessment of Readiness for College and Careers (PARCC). This workbook uses a proven performance management methodology known as "delivery" to lay out clear action steps for states and districts. It…

  3. Update on Simulation-Based Surgical Training and Assessment in Ophthalmology

    DEFF Research Database (Denmark)

    Thomsen, Ann Sofia S; Subhi, Yousif; Kiilgaard, Jens Folke;

    2015-01-01

    Library, and Web of Science) and was completed on March 1, 2014. Overall, the included trials were divided into animal, cadaver, inanimate, and virtual-reality models. Risk of bias was assessed using the Cochrane Collaboration's tool. Validity evidence was evaluated using a modern validity framework...

  4. 76 FR 36567 - Delegation of Authority for the Office of Departmental Equal Employment Opportunity

    Science.gov (United States)

    2011-06-22

    ..., the Secretary of HUD delegates concurrent authority to the Director and Deputy Director, Office of.... Authority Delegated The Secretary hereby delegates to the Director and Deputy Director, ODEEO concurrent... URBAN DEVELOPMENT Delegation of Authority for the Office of Departmental Equal Employment Opportunity...

  5. 28 CFR 0.29e - Relationship to other departmental units.

    Science.gov (United States)

    2010-07-01

    ... the ethics, competence, or integrity of a Department attorney for appropriate action by DOJ-OPR. (d... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Relationship to other departmental units. 0.29e Section 0.29e Judicial Administration DEPARTMENT OF JUSTICE ORGANIZATION OF THE DEPARTMENT...

  6. "Departmental Climate and Student Experiences in Geography Graduate Programs": Research for Enhancing Departments and Graduate Education

    Science.gov (United States)

    Solem, Michael N.; Lee, Jenny; Schlemper, M. Beth

    2011-01-01

    This article reports the authors' research which combined quantitative and qualitative methods to analyze a rather intangible phenomenon of interest to higher education researchers and administrators, that being "departmental climate" (often referred to as "academic climate"). This investigation required the authors to develop a method by which…

  7. Telling Our Story: A Case Study of a Collaborative Departmental Blog at Syracuse University Libraries

    Science.gov (United States)

    Rauh, Anne E.; McReynolds, Stephanie J. H.

    2016-01-01

    This case study will take readers through the planning and publication process of a collaborative departmental library blog at Syracuse University, which is a large private, non-profit research intensive university located in central New York State. It will provide an overview of the history of the project and the mission of the blog. It will…

  8. The Departmental Script as an Ongoing Conversation into the Phronesis of Teaching Science as Inquiry

    Science.gov (United States)

    Melville, Wayne; Campbell, Todd; Fazio, Xavier; Bartley, Anthony

    2012-01-01

    This article investigates the extent to which a science department script supports the teaching and learning of science as inquiry and how this script is translated into individual teachers' classrooms. This study was completed at one school in Canada which, since 2000, has developed a departmental script supportive of teaching and learning of…

  9. 28 CFR 0.39c - Relationship to other departmental units.

    Science.gov (United States)

    2010-07-01

    ... JUSTICE 2-Office of Professional Responsibility § 0.39c Relationship to other departmental units. (a) Primary responsibility for assuring the maintenance of the highest standards of professional responsibility by Department employees rests with the heads of the offices, divisions, bureaus, and boards of the...

  10. Quality Improvement-Focused Departmental Grand Rounds Reports: A Strategy to Engage General Surgery Residents.

    Science.gov (United States)

    Abelson, Jonathan S; Mitchell, Katrina B; Afaneh, Cheguevera; Rich, Barrie S; Frey, Theresa J; Gellman, Carol; Pomp, Alfons; Michelassi, Fabrizio

    2016-05-01

    Background Many institutions are seeking ways to enhance their surgical trainees' quality improvement (QI) skills. Objective To educate trainees about the importance of lifelong performance improvement, chief residents at New York Presbyterian Hospital-Weill Cornell Medicine are members of a multidisciplinary QI team tasked with improving surgical outcomes. We describe the process and the results of this effort. Methods Our analysis used 2 data sources to assess complication rates: the National Surgical Quality Improvement Program (NSQIP) and ECOMP, our own internal complication database. Chief residents met with a multidisciplinary QI team to review complication rates from both data sources. Chief residents performed a case-by-case analysis of complications and a literature search in areas requiring improvement. Based on this information, chief residents met with the multidisciplinary team to select interventions for implementation, and delivered QI-focused grand rounds summarizing the QI process and new interventions. Results Since 2009, chief residents have presented 16 QI-focused grand rounds. Urinary tract infections (UTIs) and surgical site infections (SSIs) were the most frequently discussed. Interventions to improve UTIs and SSIs were introduced to the department of surgery through these reports in 2011 and 2012. During this time we saw improvement in outcomes as measured by NSQIP odds ratio. Conclusions Departmental grand rounds are a suitable forum to review NSQIP data and our internal, resident-collected data as a means to engage chief residents in QI improvement, and can serve as a model for other institutions to engage surgery residents in QI projects.

  11. Updating of U.S. Wood Product Life-Cycle Assessment Data for Environmental Product Declarations

    Science.gov (United States)

    Richard Bergman; Elaine Oneil; Maureen Puettmann; Ivan Eastin; Indroneil Ganguly

    2014-01-01

    The marketplace has an increasing desire for credible and transparent product eco-labels based on life-cycle assessment (LCA) data, especially involving international trade. Over the past several years, stakeholders in the U.S. wood products industry have developed many such “eco-labels” under the ISO standard of LCA-based environmental product declarations (EPDs). The...

  12. PLANNING AND ASSESSMENT MEASURES TO UPDATING RESOURCES RECYCLING EQUIPMENTS IN COLLABORATION WITH SEWAGE TREATMENT PLANTS AND WASTE INCINERATION PLANTS

    Science.gov (United States)

    Nakakubo, Toyohiko; Tokai, Akihiro; Ohno, Koichi

    This study aims to assess two biomass utilization policies: the integration of food waste treatment in a sewerage treatment plant with an anaerobic digestion tank, and the pruned branch usage as heat source for drying sludge. We focused on two points in our analysis that the impact of the increase of dewatered sludge on sludge treatment processes after digestion and the improvement of the efficiency of waste power generation plants. A developed model was applied to the case study in Kobe city and evaluated the impact until 2030 by four indicators: energy consumption, greenhouse gas (GHG) emission, phosphorus-recovery, and cost. The results showed that case 3-C, which introducing the combined sludge and food waste digestion system, pyrolysis gasification with gas engine and wood-chip boiler, could supply additional 452 TJ/y of energy, recovery 93 t-P/y of phosphorus, and reduce 38 kt-CO2eq./y of GHG while shrinking the cost by 88 million yen/y compared to business as usual types-update case.

  13. International Space Station (ISS) Plasma Contactor Unit (PCU) Utilization Plan Assessment Update

    Science.gov (United States)

    Hernandez-Pellerano, Amri; Iannello, Christopher J.; Garrett, Henry B.; Ging, Andrew T.; Katz, Ira; Keith, R. Lloyd; Minow, Joseph I.; Willis, Emily M.; Schneider, Todd A.; Whittlesey, Edward J.; Wollack, Edward J.; Wright, Kenneth H.

    2014-01-01

    The International Space Station (ISS) vehicle undergoes spacecraft charging as it interacts with Earth's ionosphere and magnetic field. The interaction can result in a large potential difference developing between the ISS metal chassis and the local ionosphere plasma environment. If an astronaut conducting extravehicular activities (EVA) is exposed to the potential difference, then a possible electrical shock hazard arises. The control of this hazard was addressed by a number of documents within the ISS Program (ISSP) including Catastrophic Safety Hazard for Astronauts on EVA (ISS-EVA-312-4A_revE). The safety hazard identified the risk for an astronaut to experience an electrical shock in the event an arc was generated on an extravehicular mobility unit (EMU) surface. A catastrophic safety hazard, by the ISS requirements, necessitates mitigation by a two-fault tolerant system of hazard controls. Traditionally, the plasma contactor units (PCUs) on the ISS have been used to limit the charging and serve as a "ground strap" between the ISS structure and the surrounding ionospheric plasma. In 2009, a previous NASA Engineering and Safety Center (NESC) team evaluated the PCU utilization plan (NESC Request #07-054-E) with the objective to assess whether leaving PCUs off during non-EVA time periods presented risk to the ISS through assembly completion. For this study, in situ measurements of ISS charging, covering the installation of three of the four photovoltaic arrays, and laboratory testing results provided key data to underpin the assessment. The conclusion stated, "there appears to be no significant risk of damage to critical equipment nor excessive ISS thermal coating damage as a result of eliminating PCU operations during non- EVA times." In 2013, the ISSP was presented with recommendations from Boeing Space Environments for the "Conditional" Marginalization of Plasma Hazard. These recommendations include a plan that would keep the PCUs off during EVAs when the

  14. Project SAFE. Update of the SFR-1 safety assessment. Phase 1. Appendix A6: Biosphere

    Energy Technology Data Exchange (ETDEWEB)

    Kautsky, U. [Swedish Nuclear Fuel and Waste Management Co., Stockholm (Sweden); Bergstroem, U. [Studsvik Eco and Safety AB, Nykoeping (Sweden)

    1998-10-01

    There has been a considerable development of models used for describing the turnover of radionuclides or other pollutants in the biosphere. New regulations require realistic assessments and description of effects on fauna and flora. Thus the use of trophic transfer models will be a more appropriate way to model the biosphere. These models take all accumulations of radio-nuclides in the ecosystem into account, not only direct pathways to man. Thus these models must be developed for this area. Moreover the turnover of loose deposits needs to be modelled. To be able to use these models there is a need to collect data on sediment composition, ecosystem structure and potential changes due e.g. sea-level fluctuations. These data will be collected from literature and where it is necessary complemented with field surveys. In some cases new models need to be developed. The integration of the geosphere and biosphere models is identified as an important issue 32 refs, 4 figs

  15. Status update: is smoke on your mind? Using social media to assess smoke exposure

    Science.gov (United States)

    Ford, Bonne; Burke, Moira; Lassman, William; Pfister, Gabriele; Pierce, Jeffrey R.

    2017-06-01

    Exposure to wildland fire smoke is associated with negative effects on human health. However, these effects are poorly quantified. Accurately attributing health endpoints to wildland fire smoke requires determining the locations, concentrations, and durations of smoke events. Most current methods for assessing these smoke events (ground-based measurements, satellite observations, and chemical transport modeling) are limited temporally, spatially, and/or by their level of accuracy. In this work, we explore using daily social media posts from Facebook regarding smoke, haze, and air quality to assess population-level exposure for the summer of 2015 in the western US. We compare this de-identified, aggregated Facebook dataset to several other datasets that are commonly used for estimating exposure, such as satellite observations (MODIS aerosol optical depth and Hazard Mapping System smoke plumes), daily (24 h) average surface particulate matter measurements, and model-simulated (WRF-Chem) surface concentrations. After adding population-weighted spatial smoothing to the Facebook data, this dataset is well correlated (R2 generally above 0.5) with the other methods in smoke-impacted regions. The Facebook dataset is better correlated with surface measurements of PM2. 5 at a majority of monitoring sites (163 of 293 sites) than the satellite observations and our model simulation. We also present an example case for Washington state in 2015, for which we combine this Facebook dataset with MODIS observations and WRF-Chem-simulated PM2. 5 in a regression model. We show that the addition of the Facebook data improves the regression model's ability to predict surface concentrations. This high correlation of the Facebook data with surface monitors and our Washington state example suggests that this social-media-based proxy can be used to estimate smoke exposure in locations without direct ground-based particulate matter measurements.

  16. The Joint Experiment for Crop Assessment and Monitoring (JECAM): Update on Multisite Inter-comparison Experiments

    Science.gov (United States)

    Jarvis, I.; Gilliams, S. J. B.; Defourny, P.

    2016-12-01

    Globally there is significant convergence on agricultural monitoring research questions. The focus of interest usually revolves around crop type, crop area estimation and near real time crop condition and yield forecasting. Notwithstanding this convergence, agricultural systems differ significantly throughout the world, reflecting the diversity of ecosystems they are located in. Consequently, a global system of systems for operational monitoring must be based on multiple approaches. Research is required to compare and assess these approaches to identify which are most appropriate for any given location. To this end the Joint Experiments for Crop Assessment and Monitoring (JECAM) was established in 2009 to as a research platform to allow the global agricultural monitoring community to work towards a set of best practices and recommendations for using earth observation data to map, monitor and report on agricultural productivity globally. The JECAM initiative brings together researchers from a large number of globally distributed, well monitored agricultural test sites that cover a range of crop types, cropping systems and climate regimes. The results of JECAM optical inter-comparison research taking place in the Stimulating Innovation for Global Monitoring of Agriculture (SIGMA) project and the Sentinel-2 for Agriculture project will be discussed. The presentation will also highlight upcoming work on a Synthetic Aperture Radar (SAR) inter-comparison study. The outcome of these projects will result in a set of best practices that cover the range of remote sensing monitoring and reporting needs, including satellite data acquisition, pre-processing techniques, information retrieval and ground data validation. These outcomes provide the R&D foundation for GEOGLAM and will help to inform the development of the GEOGLAM system of systems for global agricultural monitoring.

  17. Republic of Lithuania; Financial Sector Assessment Program Update-Technical Note-Basel Core Principles of Effective Banking Supervision Assessment

    OpenAIRE

    International Monetary Fund

    2008-01-01

    This Technical Note presents a targeted review and a follow-up on the implementation of the recommendations of the 2002 assessment of Lithuania’s compliance with the Basel Core Principles for Effective Banking Supervision. It was found that banking supervision arrangements in Lithuania were of a high standard and either fully or largely complied with the Core Principles. On one Core Principle, Lithuania was judged to be noncompliant at that time, which concerned the lack of explicit legal p...

  18. Uranium resource assessment by the Geological Survey; methodology and plan to update the national resource base

    Science.gov (United States)

    Finch, Warren Irvin; McCammon, Richard B.

    1987-01-01

    Based on the Memorandum of Understanding {MOU) of September 20, 1984, between the U.S. Geological Survey of the U.S. Department of Interior and the Energy Information Administration {EIA) of the U.S. Department of Energy {DOE), the U.S. Geological Survey began to make estimates of the undiscovered uranium endowment of selected areas of the United States in 1985. A modified NURE {National Uranium Resource Evaluation) method will be used in place of the standard NURE method of the DOE that was used for the national assessment reported in October 1980. The modified method, here named the 'deposit-size-frequency' {DSF) method, is presented for the first time, and calculations by the two methods are compared using an illustrative example based on preliminary estimates for the first area to be evaluated under the MOU. The results demonstrate that the estimate of the endowment using the DSF method is significantly larger and more uncertain than the estimate obtained by the NURE method. We believe that the DSF method produces a more realistic estimate because the principal factor estimated in the endowment equation is disaggregated into more parts and is more closely tied to specific geologic knowledge than by the NURE method. The DSF method consists of modifying the standard NURE estimation equation, U=AxFxTxG, by replacing the factors FxT by a single factor that represents the tonnage for the total number of deposits in all size classes. Use of the DSF method requires that the size frequency of deposits in a known or control area has been established and that the relation of the size-frequency distribution of deposits to probable controlling geologic factors has been determined. Using these relations, the principal scientist {PS) first estimates the number and range of size classes and then, for each size class, estimates the lower limit, most likely value, and upper limit of the numbers of deposits in the favorable area. Once these probable estimates have been refined

  19. The science of spinal motion palpation: a review and update with implications for assessment and intervention.

    Science.gov (United States)

    Nyberg, Richard Edward; Russell Smith, A

    2013-08-01

    Spinal motion palpation (SMP) is a standard component of a manual therapy examination despite questionable reliability. The present research is inconclusive as to the relevance of the findings from SMP, with respect to the patient's pain complaints. Differences in the testing methods and interpretation of spinal mobility testing are problematic. If SMP is to be a meaningful component of a spinal examination, the methods for testing and interpretation must be carefully scrutinized. The intent of this narrative review is to facilitate a better understanding of how SMP should provide the examiner with relevant information for assessment and treatment of patients with spinal pain disorders. The concept of just noticeable difference is presented and applied to SMP as a suggestion for determining the neutral zone behavior of a spinal segment. In addition, the use of a lighter, or more passive receptive palpation technique, is considered as a means for increasing tactile discrimination of spinal movement behavior. Further understanding of the scientific basis of testing SMP may improve intra- and inter-examiner reliability. The significance of the findings from SMP should be considered in context of the patient's functional problem. Methodological changes may be indicated for the performance of SMP techniques, such as central posterior-anterior (PA) pressure and passive intervertebral motion tests, in order to improve reliability. Instructors of manual therapy involved in teaching SMP should be knowledgeable of the neurophysiological processes of touch sensation so as to best advise students in the application of the various testing techniques.

  20. An updated fracture-flow model for total-system performance assessment of Yucca Mountain

    Energy Technology Data Exchange (ETDEWEB)

    Gauthier, J.H. [SPECTRA Research Institute, Albuquerque, NM (United States)

    1994-12-31

    Improvements have been made to the fracture-flow model being used in the total-system performance assessment of a potential high-level radioactive waste repository at Yucca Mountain, Nevada. The {open_quotes}weeps model{close_quotes} now includes (1) weeps of varied sizes, (2) flow-pattern fluctuations caused by climate change, and (3) flow-pattern perturbations caused by repository heat generation. Comparison with the original weeps model indicates that allowing weeps of varied sizes substantially reduces the number of weeps and the number of containers contacted by weeps. However, flow-pattern perturbations caused by either climate change or repository heat generation greatly increases the number of containers contacted by weeps. In preliminary total-system calculations, using a phenomenological container-failure and radionuclide-release model, the weeps model predicts that radionuclide releases from a high-level radioactive waste repository at Yucca Mountain will be below the EPA standard specified in 40 CFR 191, but that the maximum radiation dose to an individual could be significant. Specific data from the site are required to determine the validity of the weep-flow mechanism and to better determine the parameters to which the dose calculation is sensitive.

  1. 2010 updated assessment of undiscovered oil and gas resources of the National Petroleum Reserve in Alaska (NPRA)

    Science.gov (United States)

    Houseknecht, D.W.; Bird, K.J.; Schuenemeyer, J.H.; Attanasi, E.D.; Garrity, C.P.; Schenk, C.J.; Charpentier, R.R.; Pollastro, R.M.; Cook, T.A.; and Klett, T.R.

    2010-01-01

    Using a geology-based assessment methodology, the U.S. Geological Survey estimated mean volumes of 896 million barrels of oil (MMBO) and about 53 trillion cubic feet (TCFG) of nonassociated natural gas in conventional, undiscovered accumulations within the National Petroleum Reserve in Alaska and adjacent State waters. The estimated volume of undiscovered oil is significantly lower than estimates released in 2002, owing primarily to recent exploration drilling that revealed an abrupt transition from oil to gas and reduced reservoir quality in the Alpine sandstone 15-20 miles west of the giant Alpine oil field. The National Petroleum Reserve in Alaska (NPRA) has been the focus of oil exploration during the past decade, stimulated by the mid-1990s discovery of the adjacent Alpine field-the largest onshore oil discovery in the United States during the past 25 years. Recent activities in NPRA, including extensive 3-D seismic surveys, six Federal lease sales totaling more than $250 million in bonus bids, and completion of more than 30 exploration wells on Federal and Native lands, indicate in key formations more gas than oil and poorer reservoir quality than anticipated. In the absence of a gas pipeline from northern Alaska, exploration has waned and several petroleum companies have relinquished assets in the NPRA. This fact sheet updates U.S. Geological Survey (USGS) estimates of undiscovered oil and gas in NPRA, based on publicly released information from exploration wells completed during the past decade and on the results of research that documents significant Cenozoic uplift and erosion in NPRA. The results included in this fact sheet-released in October 2010-supersede those of a previous assessment completed by the USGS in 2002.

  2. Electronic Health Records and Meaningful Use in Local Health Departments: Updates From the 2015 NACCHO Informatics Assessment Survey

    Science.gov (United States)

    Shah, Gulzar H.

    2016-01-01

    Background: Electronic health records (EHRs) are evolving the scope of operations, practices, and outcomes of population health in the United States. Local health departments (LHDs) need adequate health informatics capacities to handle the quantity and quality of population health data. Purpose: The purpose of this study was to gain an updated view using the most recent data to identify the primary storage of clinical data, status of data for meaningful use, and characteristics associated with the implementation of EHRs in LHDs. Methods: Data were drawn from the 2015 Informatics Capacity and Needs Assessment Survey, which used a stratified random sampling design of LHD populations. Oversampling of larger LHDs was conducted and sampling weights were applied. Data were analyzed using descriptive statistics and logistic regression in SPSS. Results: Forty-two percent of LHDs indicated the use of an EHR system compared with 58% that use a non-EHR system for the storage of primary health data. Seventy-one percent of LHDs had reviewed some or all of the current systems to determine whether they needed to be improved or replaced, whereas only 6% formally conducted a readiness assessment for health information exchange. Twenty-seven percent of the LHDs had conducted informatics training within the past 12 months. LHD characteristics statistically associated with having an EHR system were having state or centralized governance, not having created a strategic plan related to informatics within the past 2 years throughout LHDs, provided informatics training in the past 12 months, and various levels of control over decisions regarding hardware allocation or acquisition, software selection, software support, and information technology budget allocation. Conclusion: A focus on EHR implementation in public health is pertinent to examining the impact of public health programming and interventions for the positive change in population health. PMID:27684614

  3. Updating soil CO2 emission experiments to assess climate change effects and extracellular soil respiration

    Science.gov (United States)

    Vidal Vazquez, Eva; Paz Ferreiro, Jorge

    2014-05-01

    Experimental work is an essential component in training future soil scientists. Soil CO2 emission is a key issue because of the potential impacts of this process on the greenhouse effect. The amount of organic carbon stored in soils worldwide is about 1600 gigatons (Gt) compared to 750 Gt in the atmosphere mostly in the form of CO2. Thus, if soil respiration increased slightly so that just 10% of the soil carbon pool was converted to CO2, atmospheric CO2 concentrations in the atmosphere could increase by one-fifth. General circulation model predictions indicate atmosphere warming between 2 and 5°C (IPCC 2007) and precipitation changes ranging from about -15 to +30%. Traditionally, release of CO2 was thought to occur only in an intracellular environment; however, recently CO2 emissions have been in irradiated soil, in the absence of microorganisms (Maire et al., 2013). Moreover, soil plays a role in the stabilization of respiration enzymes promoting CO2 release after microorganism death. Here, we propose to improve CO2 emission experiments commonly used in soil biology to investigate: 1) effects of climatic factors on soil CO2 emissions, and 2) rates of extracellular respiration in soils and how these rates are affected by environmental factors. Experiment designed to assess the effect of climate change can be conducted either in field conditions under different ecosystems (forest, grassland, cropland) or in a greenhouse using simple soil chambers. The interactions of climate change in CO2 emissions are investigated using climate-manipulation experiment that can be adapted to field or greenhouse conditions (e.g. Mc Daniel et al., 2013). The experimental design includes a control plot (without soil temperature and rain manipulation) a warming treatment as well as wetting and/or drying treatments. Plots are warmed to the target temperature by procedures such as infrared heaters (field) or radiant cable (greenhouse). To analyze extracellular respiration, rates of CO2

  4. Comparative assessment of scoring functions on an updated benchmark: 2. Evaluation methods and general results.

    Science.gov (United States)

    Li, Yan; Han, Li; Liu, Zhihai; Wang, Renxiao

    2014-06-23

    Our comparative assessment of scoring functions (CASF) benchmark is created to provide an objective evaluation of current scoring functions. The key idea of CASF is to compare the general performance of scoring functions on a diverse set of protein-ligand complexes. In order to avoid testing scoring functions in the context of molecular docking, the scoring process is separated from the docking (or sampling) process by using ensembles of ligand binding poses that are generated in prior. Here, we describe the technical methods and evaluation results of the latest CASF-2013 study. The PDBbind core set (version 2013) was employed as the primary test set in this study, which consists of 195 protein-ligand complexes with high-quality three-dimensional structures and reliable binding constants. A panel of 20 scoring functions, most of which are implemented in main-stream commercial software, were evaluated in terms of "scoring power" (binding affinity prediction), "ranking power" (relative ranking prediction), "docking power" (binding pose prediction), and "screening power" (discrimination of true binders from random molecules). Our results reveal that the performance of these scoring functions is generally more promising in the docking/screening power tests than in the scoring/ranking power tests. Top-ranked scoring functions in the scoring power test, such as X-Score(HM), ChemScore@SYBYL, ChemPLP@GOLD, and PLP@DS, are also top-ranked in the ranking power test. Top-ranked scoring functions in the docking power test, such as ChemPLP@GOLD, Chemscore@GOLD, GlidScore-SP, LigScore@DS, and PLP@DS, are also top-ranked in the screening power test. Our results obtained on the entire test set and its subsets suggest that the real challenge in protein-ligand binding affinity prediction lies in polar interactions and associated desolvation effect. Nonadditive features observed among high-affinity protein-ligand complexes also need attention.

  5. Recent investigations and updated criteria for the assessment of antibiotic resistance in food lactic acid bacteria.

    Science.gov (United States)

    Clementi, Francesca; Aquilanti, Lucia

    2011-12-01

    The worldwide use, and misuse, of antibiotics for about sixty years in the so-called antibiotic era, has been estimated in some one to ten million tons, a relevant part of which destined for non-therapeutic purposes such as growth promoting treatments for livestock or crop protection. As highly adaptable organisms, bacteria have reacted to this dramatic change in their environment by developing several well-known mechanisms of antibiotic resistance and are becoming increasingly resistant to conventional antibiotics. In recent years, commensal bacteria have become a cause of concern since they may act as reservoirs for the antibiotic resistance genes found in human pathogens. In particular, the food chain has been considered the main route for the introduction of animal and environment associated antibiotic resistant bacteria into the human gastrointestinal tract (GIT) where these genes may be transferred to pathogenic and opportunistic bacteria. As fundamental microbial communities in a large variety of fermented foods and feed, the anaerobe facultative, aerotolerant lactic acid bacteria (LAB) are likely to play a pivotal role in the resistance gene exchange occurring in the environment, food, feed and animal and human GIT. Therefore their antibiotic resistance features and their genetic basis have recently received increasing attention. The present article summarises the results of the latest studies on the most typical genera belonging to the low G + C branch of LAB. The evolution of the criteria established by European regulatory bodies to ensure a safe use of microorganisms in food and feed, including the assessment of their antibiotic resistance is also reviewed.

  6. Chemical considerations for an updated National assessment of brackish groundwater resources

    Science.gov (United States)

    McMahon, Peter B.; Bohlke, John Karl; Dahm, Katharine; Parkhurst, David L.; Anning, David W.; Stanton, Jennifer S.

    2016-01-01

    Brackish groundwater (BGW) is increasingly used for water supplies where fresh water is scarce, but the distribution and availability of such resources have not been characterized at the national scale in the United States since the 1960s. Apart from its distribution and accessibility, BGW usability is a function of the chemical requirements of the intended use, chemical characteristics of the resource, and treatment options to make the resource compatible with the use. Here, we discuss relations between these three chemical factors using national-scale examples and local case studies. In a preliminary compilation of BGW data in the United States, five water types accounted for the major-ion composition of 70% of samples. PHREEQC calculations indicate that 57–77% of samples were oversaturated with respect to barite, calcite, or chalcedony. In the study, 5–14% of samples had concentrations of arsenic, fluoride, nitrate, or uranium that exceeded drinking-water standards. In case studies of the potential use of BGW for drinking water, irrigation, and hydraulic fracturing, PHREEQC simulations of a hypothetical treatment process resembling reverse osmosis (RO) showed that BGW had the potential to form various assemblages of mineral deposits (scale) during treatment that could adversely affect RO membranes. Speciation calculations showed that most boron in the irrigation example occurred as boric acid, which has relatively low removal efficiency by RO. Results of this preliminary study indicate that effective national or regional assessments of BGW resources should include geochemical characterizations that are guided in part by specific use and treatment requirements.

  7. Chemical Considerations for an Updated National Assessment of Brackish Groundwater Resources.

    Science.gov (United States)

    McMahon, P B; Böhlke, J K; Dahm, K G; Parkhurst, D L; Anning, D W; Stanton, J S

    2016-07-01

    Brackish groundwater (BGW) is increasingly used for water supplies where fresh water is scarce, but the distribution and availability of such resources have not been characterized at the national scale in the United States since the 1960s. Apart from its distribution and accessibility, BGW usability is a function of the chemical requirements of the intended use, chemical characteristics of the resource, and treatment options to make the resource compatible with the use. Here, we discuss relations between these three chemical factors using national-scale examples and local case studies. In a preliminary compilation of BGW data in the United States, five water types accounted for the major-ion composition of 70% of samples. PHREEQC calculations indicate that 57-77% of samples were oversaturated with respect to barite, calcite, or chalcedony. In the study, 5-14% of samples had concentrations of arsenic, fluoride, nitrate, or uranium that exceeded drinking-water standards. In case studies of the potential use of BGW for drinking water, irrigation, and hydraulic fracturing, PHREEQC simulations of a hypothetical treatment process resembling reverse osmosis (RO) showed that BGW had the potential to form various assemblages of mineral deposits (scale) during treatment that could adversely affect RO membranes. Speciation calculations showed that most boron in the irrigation example occurred as boric acid, which has relatively low removal efficiency by RO. Results of this preliminary study indicate that effective national or regional assessments of BGW resources should include geochemical characterizations that are guided in part by specific use and treatment requirements.

  8. New considerations regarding the risk assessment on Tartrazine An update toxicological assessment, intolerance reactions and maximum theoretical daily intake in France.

    Science.gov (United States)

    Elhkim, Mostafa Ould; Héraud, Fanny; Bemrah, Nawel; Gauchard, Françoise; Lorino, Tristan; Lambré, Claude; Frémy, Jean Marc; Poul, Jean-Michel

    2007-04-01

    Tartrazine is an artificial azo dye commonly used in human food and pharmaceutical products. Since the last assessment carried out by the JECFA in 1964, many new studies have been conducted, some of which have incriminated tartrazine in food intolerance reactions. The aims of this work are to update the hazard characterization and to revaluate the safety of tartrazine. Our bibliographical review of animal studies confirms the initial hazard assessment conducted by the JECFA, and accordingly the ADI established at 7.5mg/kg bw. From our data, in France, the estimated maximum theoretical intake of tartrazine in children is 37.2% of the ADI at the 97.5th percentile. It may therefore be concluded that from a toxicological point of view, tartrazine does not represent a risk for the consumer. It appears more difficult to show a clear relationship between ingestion of tartrazine and the development of intolerance reactions in patients. These reactions primarily occur in patients who also suffer from recurrent urticaria or asthma. The link between tartrazine consumption and these reactions is often overestimated, and the pathogenic mechanisms remain poorly understood. The prevalence of tartrazine intolerance is estimated to be less than 0.12% in the general population. Generally, the population at risk is aware of the importance of food labelling, with the view of avoiding consumption of tartrazine. However, it has to be mentioned that products such as ice creams, desserts, cakes and fine bakery are often sold loose without any labelling.

  9. Alaska Regional Energy Resources Planning Project, Phase 2: coal, hydroelectric, and energy alternatives. Volume III. Alaska's alternative energies and regional assessment inventory update

    Energy Technology Data Exchange (ETDEWEB)

    1979-01-01

    The Alaska Regional Energy Resources Planning Project is presented in three volumes. This volume, Vol. III, considers alternative energies and the regional assessment inventory update. The introductory chapter, Chapter 12, examines the historical background, current technological status, environmental impact, applicability to Alaska, and siting considerations for a number of alternative systems. All of the systems considered use or could use renewable energy resources. The chapters that follow are entitled: Very Small Hydropower (about 12 kW or less for rural and remote villages); Low-Temperature Geothermal Space Heating; Wind; Fuel Cells; Siting Criteria and Preliminary Screening of Communities for Alternate Energy Use; Wood Residues; Waste Heat; and Regional Assessment Invntory Update. (MCW)

  10. An independent assessment of the technical feasibility of the Mars One mission plan - Updated analysis

    Science.gov (United States)

    Do, Sydney; Owens, Andrew; Ho, Koki; Schreiner, Samuel; de Weck, Olivier

    2016-03-01

    In recent years, the Mars One program has gained significant publicity for its plans to colonize the red planet. Beginning in 2025, the program plans to land four people on Mars every 26 months via a series of one-way missions, using exclusively existing technology. This one-way approach has frequently been cited as a key enabler of accelerating the first crewed landing on Mars. While the Mars One program has received considerable attention, little has been published in the technical literature regarding the formulation of its mission architecture. In light of this, we perform an independent analysis of the technical feasibility of the Mars One mission plan, focusing on the architecture of the life support and in-situ resource utilization (ISRU) systems, and their impact on sparing and space logistics. To perform this analysis, we adopt an iterative analysis approach in which we model and simulate the mission architecture, assess its feasibility, implement any applicable modifications while attempting to remain within the constraints set forth by Mars One, and then resimulate and reanalyze the revised version of the mission architecture. Where required information regarding the Mars One mission architecture is not available, we assume numerical values derived from standard spaceflight design handbooks and documents. Through four iterations of this process, our analysis finds that the Mars One mission plan, as publicly described, is not feasible. This conclusion is obtained from analyses based on mission assumptions derived from and constrained by statements made by Mars One, and is the result of the following findings: (1) several technologies including ISRU, life support, and entry, descent, and landing (EDL) are not currently "existing, validated and available" as claimed by Mars One; (2) the crop growth area described by Mars One is insufficient to feed their crew; (3) increasing the crop growth area to provide sufficient food for the crew leads to atmospheric

  11. TRACKING AND MONITORING OF TAGGED OBJECTS EMPLOYING PARTICLE SWARM OPTIMIZATION ALGORITHM IN A DEPARTMENTAL STORE

    Directory of Open Access Journals (Sweden)

    Indrajit Bhattacharya

    2011-05-01

    Full Text Available The present paper proposes a departmental store automation system based on Radio Frequency Identification (RFID technology and Particle Swarm Optimization (PSO algorithm. The items in the departmental store spanned over different sections and in multiple floors, are tagged with passive RFID tags. The floor is divided into number of zones depending on different types of items that are placed in their respective racks. Each of the zones is placed with one RFID reader, which constantly monitors the items in their zone and periodically sends that information to the application. The problem of systematic periodic monitoring of the store is addressed in this application so that the locations, distributions and demands of every item in the store can be invigilated with intelligence. The proposed application is successfully demonstrated on a simulated case study.

  12. Sustainable Change: A Model for Transforming Departmental Culture to Support STEM Education Innovation

    CERN Document Server

    Corbo, Joel C; Dancy, Melissa H; Deetz, Stanley; Finkelstein, Noah

    2014-01-01

    This paper describes a strategic effort to improve teaching and learning in STEM departments at the University of Colorado Boulder. In contrast to many other higher education STEM change efforts that focus primarily on disseminating practices, our two synergistic change strategies focus on explicit cultural change that integrates interventions across the entire university system, impacting faculty members, administrators, and, most importantly, whole departments. Our outside-in strategy works with both faculty and administrators to create changes that will combine to influence departmental culture, and our middle-out strategy works directly with departments to enact a large-scale cultural change process. Both of these strategies aim to align departmental cultures with six core cultural commitments that are emblematic of highly productive departments. We argue that this holistic approach to shifting culture is required to foster and sustain meaningful change. Additionally, our strategies are grounded in change...

  13. Doctoral Advisor-Advisee Pairing in STEM Fields: Selection Criteria and Impact of Faculty, Student and Departmental Factors

    Directory of Open Access Journals (Sweden)

    Simy Joy

    2015-09-01

    Full Text Available Unlike the doctoral programs in places where students are paired with advisors at the time of admission itself, most US programs require the students to choose their advisors, and the advisors to formally accept the students as advisees. Little research has been done to understand how students and faculty approach this mutual selection and pairing process. This paper examines this process in STEM departments (Science, Technology, Engineering and Mathematics, with specific focus on factors influencing the decisions. Based on focus groups and interviews of doctoral students and faculty from STEM departments in an American university, we identify criteria applied by students and faculty in making their choices. Students were found to assess faculty on available funding, area of research, personality, ability to graduate students fast, and career prospects for students, and faculty to assess students on their qualifications/credentials and perceived ability to contribute to research. We also found that this mutual assessment was not objective, but influenced by perceptions associated with faculty gender and career stage, and student nationality. In the end, whether students and faculty were actually paired with persons of their choice depended on departmental factors including prevalent pairing practices, restrictions on student numbers per faculty, and reward structure. We discuss implications of the findings for research and practice.

  14. Departmentalization and Organizational Context: The Experience of the University of Guadalajara

    OpenAIRE

    Adrián Acosta Silva

    2005-01-01

    This work consists of an evaluation of the experience of organizational reform and academic departmentalization at a Mexican public university, the University of Guadalajara (U. of G.), occurred in the period of 1994-2005. It is a research carried out from the perspective of the institutional change analysis, which obeys the interest of carrying out a rigorous evaluation of the process, after 11 years of its institutional operation. From a reconstruction of the context that gave origin and se...

  15. A Model for the Departmental Quality Management Infrastructure Within an Academic Health System.

    Science.gov (United States)

    Mathews, Simon C; Demski, Renee; Hooper, Jody E; Biddison, Lee Daugherty; Berry, Stephen A; Petty, Brent G; Chen, Allen R; Hill, Peter M; Miller, Marlene R; Witter, Frank R; Allen, Lisa; Wick, Elizabeth C; Stierer, Tracey S; Paine, Lori; Puttgen, Hans A; Tamargo, Rafael J; Pronovost, Peter J

    2016-09-06

    As quality improvement and patient safety come to play a larger role in health care, academic medical centers and health systems are poised to take a leadership role in addressing these issues. Academic medical centers can leverage their large integrated footprint and have the ability to innovate in this field. However, a robust quality management infrastructure is needed to support these efforts. In this context, quality and safety are often described at the executive level and at the unit level. Yet, the role of individual departments, which are often the dominant functional unit within a hospital, in realizing health system quality and safety goals has not been addressed. Developing a departmental quality management infrastructure is challenging because departments are diverse in composition, size, resources, and needs.In this article, the authors describe the model of departmental quality management infrastructure that has been implemented at the Johns Hopkins Hospital. This model leverages the fractal approach, linking departments horizontally to support peer and organizational learning and connecting departments vertically to support accountability to the hospital, health system, and board of trustees. This model also provides both structure and flexibility to meet individual departmental needs, recognizing that independence and interdependence are needed for large academic medical centers. The authors describe the structure, function, and support system for this model as well as the practical and essential steps for its implementation. They also provide examples of its early success.

  16. Update to agency for toxic substances and disease registry 2012 report on assessment of biota exposure to mercury originating from Savannah River Site.

    Energy Technology Data Exchange (ETDEWEB)

    Kuhne, W. [Savannah River Site (SRS), Aiken, SC (United States)

    2015-08-10

    The purpose of this report is to 1) update previous Savannah River National Laboratory (SRNL) assessment reports (Kvartek et al. 1994 and Halverson et al. 2008) on the fate of mercury in the Savannah River Site (SRS) environment and 2) address comments and recommendations from the review of SRS by the Agency for Toxic Substances and Disease Registry (ATSDR) concerning the evaluation of exposures to contaminants in biota originating from the SRS. The ATSDR reviewed and evaluated data from SRS, South Carolina Department of Health & Environmental Control (SCDHEC) and the Georgia Department of Natural Resources (GDNR) concerning the non-radioactive contaminant mercury. This report will provide a response and update to conclusions and recommendations made by the ATSDR.

  17. December 2012 Policy Update: School Climate and Bully Prevention Trends State-by-State Assessment. School Climate Brief, Number 6

    Science.gov (United States)

    Bellizio, Dan

    2012-01-01

    This December 2012 Brief updates NSCC's 2011 report "State Policies on School Climate and Bully Prevention Efforts: Challenges and Opportunities for Deepening State Policy Support for Safe and Civil School"s (www.schoolclimate.org/climate/papers-briefs.php). This Brief provides a summary of State level: (1) anti-bullying legislation; (2)…

  18. TOOLS FOR DETERMINING SUSTAINABLE WASTE MANAGEMENT THROUGH APPLICATION OF LIFE-CYCLE ASSESSMENT: UPDATE ON U.S. RESEARCH

    Science.gov (United States)

    The paper is an update on U.S. research to develop tools and information for evaluating integrated solid waste management strategies. In the past, waste management systems consisted primarily of waste collection and disposal at a local landfill. Today's municipal solid waste ma...

  19. Website updates

    Data.gov (United States)

    National Aeronautics and Space Administration — Updates to Website: (Please add new items at the top of this description with the date of the website change) May 9, 2012: Uploaded experimental data in matlab...

  20. Circular Updates

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Circular Updates are periodic sequentially numbered instructions to debriefing staff and observers informing them of changes or additions to scientific and specimen...

  1. Cybersecurity Update

    CERN Document Server

    Heagerty, Denise

    2008-01-01

    An update on recent security issues and vulnerabilities affecting Windows, Linux and Mac platforms. This talk is based on contributions and input from a range of colleagues both within and outside CERN. It covers clients, servers and control systems.

  2. A departmental audit of patients with bladder cancer.

    Science.gov (United States)

    Sahabudin, R. M.; Persad, R. A.; Mishriki, F.; Feneley, R. C.

    1992-01-01

    In keeping with the recent demands of the Department of Health for medical audit in clinical practice, an audit was undertaken of the management of bladder cancer patients in a large department of urology having three consultants with varied approaches of management. This study revealed interesting controversial areas for further scrutiny. For example, the poor prognosis of grade 3 T1 tumours with and without associated carcinoma-in-situ (CIS) and the speed of progression to invasive disease have indicated that a change to a more aggressive approach to the management of these tumours is necessary. High recurrence rates at the site of the original tumour (60%) and the presence of CIS also indicate the need for expert and thorough initial tumour assessment. The delays in diagnosis and treatment lend further support to the need for a 'haematuria clinic' to minimise such delays, which may influence prognosis. To reduce the occurrence of systematic errors in the recording, follow-up and surveillance of patients with bladder cancer, a protocol is suggested for a structured approach to optimise results, particularly in the poor prognostic categories. PMID:1416708

  3. Measurable improvement in patient safety culture: A departmental experience with incident learning.

    Science.gov (United States)

    Kusano, Aaron S; Nyflot, Matthew J; Zeng, Jing; Sponseller, Patricia A; Ermoian, Ralph; Jordan, Loucille; Carlson, Joshua; Novak, Avrey; Kane, Gabrielle; Ford, Eric C

    2015-01-01

    Rigorous use of departmental incident learning is integral to improving patient safety and quality of care. The goal of this study was to quantify the impact of a high-volume, departmental incident learning system on patient safety culture. A prospective, voluntary, electronic incident learning system was implemented in February 2012 with the intent of tracking near-miss/no-harm incidents. All incident reports were reviewed weekly by a multiprofessional team with regular department-wide feedback. Patient safety culture was measured at baseline with validated patient safety culture survey questions. A repeat survey was conducted after 1 and 2 years of departmental incident learning. Proportional changes were compared by χ(2) or Fisher exact test, where appropriate. Between 2012 and 2014, a total of 1897 error/near-miss incidents were reported, representing an average of 1 near-miss report per patient treated. Reports were filed by a cross section of staff, with the majority of incidents reported by therapists, dosimetrists, and physicists. Survey response rates at baseline and 1 and 2 years were 78%, 80%, and 80%, respectively. Statistically significant and sustained improvements were noted in several safety metrics, including belief that the department was openly discussing ways to improve safety, the sense that reports were being used for safety improvement, and the sense that changes were being evaluated for effectiveness. None of the surveyed dimensions of patient safety culture worsened. Fewer punitive concerns were noted, with statistically significant decreases in the worry of embarrassment in front of colleagues and fear of getting colleagues in trouble. A comprehensive incident learning system can identify many areas for improvement and is associated with significant and sustained improvements in patient safety culture. These data provide valuable guidance as incident learning systems become more widely used in radiation oncology. Copyright © 2015

  4. Design of Student Information Management Database Application System for Office and Departmental Target Responsibility System

    Science.gov (United States)

    Zhou, Hui

    It is the inevitable outcome of higher education reform to carry out office and departmental target responsibility system, in which statistical processing of student's information is an important part of student's performance review. On the basis of the analysis of the student's evaluation, the student information management database application system is designed by using relational database management system software in this paper. In order to implement the function of student information management, the functional requirement, overall structure, data sheets and fields, data sheet Association and software codes are designed in details.

  5. Supporting Hospital Inter-departmental Coordination of work with Electronic Whiteboards

    DEFF Research Database (Denmark)

    Lassen, Jens Vejrup; Simonsen, Jesper

    We present an ethnographic study of the organizational aspects of the use of an electronic whiteboard (EW) system implemented in a Danish hospital located in Nykøbing Falster (NFH) . The EW system had originally been developed for the emergency department (ED), but had later been extended...... to the entire hospital, and the study was conducted about 10 months after that time. The study focuses on coordination regarding inter-departmental ordering of surgical operations via the EW system. The research question asked whether clinicians experienced impacts or consequences, and the challenges...... and demonstrate the complexity of organizing cooperative work using artifacts and technology across organizational units....

  6. 75 FR 81037 - Waste Confidence Decision Update

    Science.gov (United States)

    2010-12-23

    ... COMMISSION 10 CFR Part 51 Waste Confidence Decision Update AGENCY: Nuclear Regulatory Commission. ACTION: Update and final revision of Waste Confidence Decision. SUMMARY: The U.S. Nuclear Regulatory Commission... update to the Decision were products of rulemaking proceedings designed to assess the degree of...

  7. CATL Update

    Science.gov (United States)

    2011-03-24

    2010 Report sent NATC CATL 1922 20K Treadwear Bridgestone 2 LT235/85R16 (L/R E) GMC 2500 (2WD) Awaiting new control tire NATC CATL 1922 20K Treadwear...1 DSCC Annual Tire Conference CATL UPDATE March 24, 2011 UNCLASSIFIED: Dist A. Approved for public release Report Documentation Page...A 3. DATES COVERED - 4. TITLE AND SUBTITLE CATL Update 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d

  8. Commentary: Mentoring the mentor: executive coaching for clinical departmental executive officers.

    Science.gov (United States)

    Geist, Lois J; Cohen, Michael B

    2010-01-01

    Departmental executive officers (DEOs), department chairs, and department heads in medical schools are often hired on the basis of their accomplishments in research as well as their skills in administration, management, and leadership. These individuals are also expected to be expert in multiple areas, including negotiation, finance and budgeting, mentoring, and personnel management. At the same time, they are expected to maintain and perhaps even enhance their personal academic standing for the purposes of raising the level of departmental and institutional prestige and for recruiting the next generation of physicians and scientists. In the corporate world, employers understand the importance of training new leaders in requisite skill enhancement that will lead to success in their new positions. These individuals are often provided with extensive executive training to develop the necessary competencies to make them successful leaders. Among the tools employed for this purpose are the use of personal coaches or executive training courses. The authors propose that the use of executive coaching in academic medicine may be of benefit for new DEOs. Experience using an executive coach suggests that this was a valuable growth experience for new leaders in the institution.

  9. Research of the Relationship between Government Comprehensive Statistics and Departmental Statistics%政府综合统计与部门统计关系

    Institute of Scientific and Technical Information of China (English)

    叶长法

    2005-01-01

    The paper reviews the history of foundation of governmental statistics of China, analyzes the main problems of governmental statistics and the causes of the problems, and forwards some policy suggestions to rationalize the relationship of governmental comprehensive statistics and governmental departmental statistics and strengthen the departmental statistics administration.

  10. The application of objective structured clinical examination in the departmental rotation ex-amination of periodontal clinical assessment%客观结构化临床考试应用于牙周临床出科考核的探索

    Institute of Scientific and Technical Information of China (English)

    李丹; 陈悦; 张江琳; 杨相笛; 王浩宇; 高歌; 侯铁舟

    2015-01-01

    To improve the clinical teaching work, the objective structured clinical examination (OSCE) was first introduced into the periodontal clinical assessment held by Departments of Periodon-titis and Mucosal Disease. With the OSCE exam station and item pool established, standardized pa-tients tralned, the examination form reformed, the knowledge, skill, and attitude of the examinee were assessed comprehensively. Compared with traditional exam,the OSCE evaluated the examinee's skills on clinical admissions, history collection, treatment plan development better. Most examinee have got satisfactory result (pass rate: 86.4 %, 19/22; good rate: 36.4%, 8/22; excellent rate: 9.1%, 2/22). The feedback of the following questionnalre also showed that most of the candidates thought the OSCE helpful to promoting the learning of theoretical knowledge (87.5%, 14/16) and good for converting the learned knowledge and skills into occupation ability (87.5%, 14/16).%为改进我院牙周病学临床教学,我院牙周黏膜科首次引入客观结构化临床考试(objective structured clinical examination,OSCE)应用于牙周病学出科考核。通过设立OSCE考站、建立题库、培训标准化病人(SP),对考生的知识、技能、态度进行全面评估。较之于传统考核,本次考核较好地评价了考生在临床接诊、病史采集、治疗计划制定等方面的能力。本次考核合格率86.4%(19/22),良好率36.4%(8/22),优秀率9.1%(2/22)。之后的问卷调查显示,大部分考生认为OSCE有助于促进理论知识的学习(87.5%,14/16),有利于自身将学到的知识和技能转化为职业能力(87.5%,14/16)。

  11. Performance and quality assessment of the recent updated CMEMS global ocean monitoring and forecasting real-time system

    Science.gov (United States)

    Le Galloudec, Olivier; Lellouche, Jean-Michel; Greiner, Eric; Garric, Gilles; Régnier, Charly; Drévillon, Marie; Drillet, Yann

    2017-04-01

    Since May 2015, Mercator Ocean opened the Copernicus Marine Environment and Monitoring Service (CMEMS) and is in charge of the global eddy resolving ocean analyses and forecast. In this context, Mercator Ocean currently delivers in real-time daily services (weekly analyses and daily forecast) with a global 1/12° high resolution system. The model component is the NEMO platform driven at the surface by the IFS ECMWF atmospheric analyses and forecasts. Observations are assimilated by means of a reduced-order Kalman filter with a 3D multivariate modal decomposition of the forecast error. It includes an adaptive-error estimate and a localization algorithm. Along track altimeter data, satellite Sea Surface Temperature and in situ temperature and salinity vertical profiles are jointly assimilated to estimate the initial conditions for numerical ocean forecasting. A 3D-Var scheme provides a correction for the slowly-evolving large-scale biases in temperature and salinity. R&D activities have been conducted at Mercator Ocean these last years to improve the real-time 1/12° global system for recent updated CMEMS version in 2016. The ocean/sea-ice model and the assimilation scheme benefited of the following improvements: large-scale and objective correction of atmospheric quantities with satellite data, new Mean Dynamic Topography taking into account the last version of GOCE geoid, new adaptive tuning of some observational errors, new Quality Control on the assimilated temperature and salinity vertical profiles based on dynamic height criteria, assimilation of satellite sea-ice concentration, new freshwater runoff from ice sheets melting, … This presentation will show the impact of some updates separately, with a particular focus on adaptive tuning experiments of satellite Sea Level Anomaly (SLA) and Sea Surface Temperature (SST) observations errors. For the SLA, the a priori prescribed observation error is globally greatly reduced. The median value of the error changed

  12. Working Memory Updating as a Predictor of Academic Attainment

    Science.gov (United States)

    Lechuga, M. Teresa; Pelegrina, Santiago; Pelaez, Jose L.; Martin-Puga, M. Eva; Justicia, M. Jose

    2016-01-01

    There is growing evidence supporting the importance of executive functions, and specifically working memory updating (WMU), for children's academic achievement. This study aimed to assess the specific contribution of updating to the prediction of academic performance. Two updating tasks, which included different updating components, were…

  13. Departmentalized, Self-Contained, or Somewhere in Between: Understanding Elementary Grade-Level Organizational Decision-Making

    Science.gov (United States)

    Parker, Audra; Rakes, Lori; Arndt, Katie

    2017-01-01

    Recent trends indicate a move away from self-contained classrooms and toward content-focused departmentalization in elementary schools. This study takes a snapshot of the existing organizational structures used in elementary schools in one district and explores administrators' beliefs and practices regarding this phenomenon. Our findings suggest…

  14. 42 CFR 422.1074 - Right to request Departmental Appeals Board review of Administrative Law Judge's decision or...

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Right to request Departmental Appeals Board review of Administrative Law Judge's decision or dismissal. 422.1074 Section 422.1074 Public Health CENTERS... MEDICARE ADVANTAGE PROGRAM Appeal procedures for Civil Money Penalties § 422.1074 Right to...

  15. 42 CFR 423.1074 - Right to request Departmental Appeals Board review of Administrative Law Judge's decision or...

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Right to request Departmental Appeals Board review of Administrative Law Judge's decision or dismissal. 423.1074 Section 423.1074 Public Health CENTERS... VOLUNTARY MEDICARE PRESCRIPTION DRUG BENEFIT Appeal Procedures for Civil Money Penalties § 423.1074 Right...

  16. The Relationship between Departmental Power and Faculty Careers on Two Campuses: The Case for Structural Effects on Faculty Salaries.

    Science.gov (United States)

    Moore, William L.; Pfeffer, Jeffrey

    1980-01-01

    The rate of faculty advancement through steps within ranks were examined in a sample of 40 departments on two campuses of a large state university system. The proportion of departmental faculty moving through steps faster than normal was correlated with the political power of the department on the campus. (Author/MLW)

  17. Self-Contained versus Departmentalized Settings in Urban Elementary Schools: An Analysis of Fifth-Grade Student Mathematics Performance

    Science.gov (United States)

    Jack, Diamond Marie

    2014-01-01

    Student achievement in mathematics, particularly in urban areas, is a consistent concern in the United States. Research suggests that teachers either are under qualified or have a negative perception of themselves as mathematics teachers. Departmentalization on the elementary level is an organizational structure that may benefit urban students and…

  18. 2010 Manufacturing Readiness Assessment Update to the 2008 Report for Fuel Cell Stacks and Systems for the Backup Power and Materials Handling Equipment Markets

    Energy Technology Data Exchange (ETDEWEB)

    Wheeler, D.; Ulsh, M.

    2012-08-01

    In 2008, the National Renewable Energy Laboratory (NREL), under contract to the US Department of Energy (DOE), conducted a manufacturing readiness assessment (MRA) of fuel cell systems and fuel cell stacks for back-up power and material handling applications (MHE). To facilitate the MRA, manufacturing readiness levels (MRL) were defined that were based on the Technology Readiness Levels previously established by the US Department of Energy (DOE). NREL assessed the extensive existing hierarchy of MRLs developed by Department of Defense (DoD) and other Federal entities, and developed a MRL scale adapted to the needs of the Fuel Cell Technologies Program (FCTP) and to the status of the fuel cell industry. The MRL ranking of a fuel cell manufacturing facility increases as the manufacturing capability transitions from laboratory prototype development through Low Rate Initial Production to Full Rate Production. DOE can use MRLs to address the economic and institutional risks associated with a ramp-up in polymer electrolyte membrane (PEM) fuel cell production. In 2010, NREL updated this assessment, including additional manufacturers, an assessment of market developments since the original report, and a comparison of MRLs between 2008 and 2010.

  19. Advanced course for doctors as Departmental IT Network Administrators in anesthesia and intensive care units.

    Science.gov (United States)

    Lanza, Vincenzo; Huang, Chun-Hsi

    2006-10-01

    The design and administration of a departmental computer network (Local Area Network) in anesthesiology and intensive care offer the opportunity to manage clinical information and control the work-flow. To improve the local network, after basic design, intelligence is necessary to maintain its efficiency. For this reason the role of a medical administrator of the network is fundamental because he is a qualified figure who recognizes the most important characteristics that a network must have, knows the users of the system, represents a valid consultant for the technician that has to build the network, and is able to face possible breakdowns. This paper illustrates the structure of a course to train a medical network administrator in anesthesiology and critical care.

  20. Fostering Change from Within: Influencing Teaching Practices of Departmental Colleagues by Science Faculty with Education Specialties.

    Science.gov (United States)

    Bush, Seth D; Rudd, James A; Stevens, Michael T; Tanner, Kimberly D; Williams, Kathy S

    2016-01-01

    Globally, calls for the improvement of science education are frequent and fervent. In parallel, the phenomenon of having Science Faculty with Education Specialties (SFES) within science departments appears to have grown in recent decades. In the context of an interview study of a randomized, stratified sample of SFES from across the United States, we discovered that most SFES interviewed (82%) perceived having professional impacts in the realm of improving undergraduate science education, more so than in research in science education or K-12 science education. While SFES reported a rich variety of efforts towards improving undergraduate science education, the most prevalent reported impact by far was influencing the teaching practices of their departmental colleagues. Since college and university science faculty continue to be hired with little to no training in effective science teaching, the seeding of science departments with science education specialists holds promise for fostering change in science education from within biology, chemistry, geoscience, and physics departments.

  1. An Updated Probabilistic Seismic Hazard Assessment for Romania and Comparison with the Approach and Outcomes of the SHARE Project

    Science.gov (United States)

    Pavel, Florin; Vacareanu, Radu; Douglas, John; Radulian, Mircea; Cioflan, Carmen; Barbat, Alex

    2016-06-01

    The probabilistic seismic hazard analysis for Romania is revisited within the framework of the BIGSEES national research project (http://infp.infp.ro/bigsees/default.htm) financed by the Romanian Ministry of Education and Scientific Research in the period 2012-2016. The scope of this project is to provide a refined description of the seismic action for Romanian sites according to the requirements of Eurocode 8. To this aim, the seismicity of all the sources influencing the Romanian territory is updated based on new data acquired in recent years. The ground-motion models used in the analysis, as well as their corresponding weights, are selected based on the results from several recent papers also published within the framework of the BIGSEES project. The seismic hazard analysis for Romania performed in this study are based on the traditional Cornell-McGuire approach. Finally, the results are discussed and compared with the values obtained in the recently completed SHARE research project. The BIGSEES and SHARE results are not directly comparable since the considered soil conditions are different—actual soil classes for BIGSEES and rock for SHARE. Nevertheless, the analyses of the seismic hazard results for 200 sites in Romania reveal considerable differences between the seismic hazard levels obtained in the present study and the SHARE results and point out the need for further analyses and thorough discussions related to the two seismic hazard models, especially in the light of a possible future harmonized hazard map for Europe.

  2. 2016 update on eating disorders in athletes: A comprehensive narrative review with a focus on clinical assessment and management.

    Science.gov (United States)

    Joy, Elizabeth; Kussman, Andrea; Nattiv, Aurelia

    2016-02-01

    Eating disorders, such as anorexia nervosa and bulimia nervosa, can have devastating effects on both the health and performance of athletes. Compared to non-athletes, both female and male athletes are at higher risk of developing an eating disorder. This is especially true for athletes participating in sports where low body weight or leanness confers a competitive advantage. Screening for disordered eating behaviours, eating disorders and for related health consequences should be a standard component of preparticipation examinations, and team physicians should be knowledgeable of the updated diagnostic criteria for eating disorders in the Diagnostic and Statistical Manual-V. Athletes with eating disorders should undergo thorough evaluation and treatment by an experienced multidisciplinary team. Team physicians play a critical role in decision-making on clearance for participation and return to play. Using evidence-based guidelines for clearance and return to play encourages transparency and accountability between the sports medicine care team and the athlete. Efforts to prevent eating disorders should be aimed at athletes, coaches, parents and athletic administrators, and focused on expanding knowledge of healthy nutrition in support of sport performance and health.

  3. Assessing the disturbed rock zone (DRZ) around a 655 meter vertical shaft in salt using ultrasonic waves: An update

    Energy Technology Data Exchange (ETDEWEB)

    HARDY,ROBERT D.; HOLCOMB,DAVID J.

    2000-03-14

    An array of ultrasonic transducers was constructed consisting of three identical arrays at various depths in an air intake shaft at the Waste Isolation Pilot Plant (WIPP). Each array consists of transducers permanently installed in three holes arranged in an L shape. An active array, created by appropriate arrangement of the transducers and selection of transmitter-receiver pairs, allows the measurement of transmitted signal velocities and amplitudes (for attenuation studies) along 216 paths parallel, perpendicular and tangential to the shaft walls. Transducer positions were carefully surveyed, allowing absolute velocity measurements. Installation occurred over a period of about two years beginning in early 1989, with nearly continuous operation since that time, resulting in a rare, if not unique, record of the spatial and temporal variability of damage development around an underground opening. This paper reports results from the last two years of operation, updating the results reported by Holcomb, 1999. Results will be related to the damage, due to microcracking, required to produce the observed changes. It is expected that the results will be useful to other studies of the long-term deformation characteristics of salt.

  4. Assessing and conceptualizing frontal EEG asymmetry: An updated primer on recording, processing, analyzing, and interpreting frontal alpha asymmetry.

    Science.gov (United States)

    Smith, Ezra E; Reznik, Samantha J; Stewart, Jennifer L; Allen, John J B

    2017-01-01

    Frontal electroencephalographic (EEG) alpha asymmetry is widely researched in studies of emotion, motivation, and psychopathology, yet it is a metric that has been quantified and analyzed using diverse procedures, and diversity in procedures muddles cross-study interpretation. The aim of this article is to provide an updated tutorial for EEG alpha asymmetry recording, processing, analysis, and interpretation, with an eye towards improving consistency of results across studies. First, a brief background in alpha asymmetry findings is provided. Then, some guidelines for recording, processing, and analyzing alpha asymmetry are presented with an emphasis on the creation of asymmetry scores, referencing choices, and artifact removal. Processing steps are explained in detail, and references to MATLAB-based toolboxes that are helpful for creating and investigating alpha asymmetry are noted. Then, conceptual challenges and interpretative issues are reviewed, including a discussion of alpha asymmetry as a mediator/moderator of emotion and psychopathology. Finally, the effects of two automated component-based artifact correction algorithms-MARA and ADJUST-on frontal alpha asymmetry are evaluated.

  5. Scientific Opinion updating the risk assessment conclusions and risk management recommendations on the genetically modified insect resistant maize MON 810

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Genetically Modified Organisms (GMO

    2012-12-01

    Full Text Available Following a request from the European Commission, the Panel on Genetically Modified Organisms of the European Food Safety Authority (EFSA GMO Panel compiled its previous risk assessment conclusions and risk management recommendations on the genetically modified insect resistant maize MON 810, and considered their validity in the light of new relevant scientific publications published from 2009 onwards. Following a search of the scientific literature published between 2009 and October 2012, the EFSA GMO Panel identified 165 peer-reviewed publications containing evidence specific to the risk assessment and/or management of maize MON 810, of which 68 publications were discussed and/or cited in previous EFSA GMO Panel scientific outputs. From the remaining 97 publications, eight were relevant for the molecular characterisation, 27 for food and feed safety assessment, 55 for the environmental risk assessment and/or risk management, two for the molecular characterisation and the environmental risk assessment and/or risk management and five for the food and feed safety assessment and the environmental risk assessment and/or risk management of maize MON 810. None of these publications reported new information that would invalidate the previous conclusions on the safety of maize MON 810 made by the EFSA GMO Panel. Therefore, the EFSA GMO Panel considers that its previous risk assessment conclusions on maize MON 810, as well as its previous recommendations on risk mitigation measures and monitoring, remain valid and applicable.

  6. Cohort profile update: 2004 Pelotas (Brazil) Birth Cohort Study. Body composition, mental health and genetic assessment at the 6 years follow-up.

    Science.gov (United States)

    Santos, Iná S; Barros, Aluísio J D; Matijasevich, Alicia; Zanini, Roberta; Chrestani Cesar, Maria Aurora; Camargo-Figuera, Fabio Alberto; Oliveira, Isabel O; Barros, Fernando C; Victora, Cesar G

    2014-10-01

    This is an update of the 2004 Pelotas Birth Cohort profile, originally published in 2011. In view of the high prevalence of overweight and mental health problems among Brazilian children, together with the availability of state-of-the-art equipment to assess body composition and diagnostic tests for mental health in childhood, the main outcomes measured in the fifth follow-up (mean age 6.8 years) included child body composition, mental health and cognitive ability. A total of 3722 (90.2%) of the original mothers/carers were interviewed and their children examined in a clinic where they underwent whole-body dual X-ray absorptiometry (DXA), air displacement plethysmography and a 3D photonic scan. Saliva samples for DNA were obtained. Clinical psychologists applied the Development and Well-Being Assessment questionnaire and the Wechsler Intelligence Scale for Children to all children. Results are being compared with those of the two earlier cohorts to assess the health effects of economic growth and full implementation of public policies aimed at reducing social inequalities in the past 30 years. For further information visit the programme website at [http://www.epidemio-ufpel.org.br/site/content/coorte_2004/questionarios.php]. Applications to use the data should be made by contacting 2004 cohort researchers and filling in the application form available at [http://www.epidemio-ufpel.org.br/site/content/estudos/formularios.php].

  7. Scientific Opinion updating the risk assessment conclusions and risk management recommendations on the genetically modified insect resistant maize 1507

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Genetically Modified Organisms (GMO

    2012-10-01

    Full Text Available

    Following a request from the European Commission, the Panel on Genetically Modified Organisms of the European Food Safety Authority (EFSA GMO Panel compiled its previous risk assessment conclusions and risk management recommendations on the genetically modified insect resistant maize 1507, and considered their validity in the light of new relevant scientific publications published from 2005 onwards. The EFSA GMO Panel performed a search of the scientific literature published between 2005 and September 2012, and identified 61 peer-reviewed publications containing evidence specific to the risk assessment and/or management of maize 1507, of which two were relevant for the food and feed safety assessment, and 34 for the environmental risk assessment and/or risk management. None of these publications reported new information that would invalidate the previous conclusions on the safety of maize 1507 made by the EFSA GMO Panel. Therefore, the EFSA GMO Panel considers that its previous risk assessment conclusions on maize 1507, as well as its previous recommendations on risk mitigation measures and monitoring, remain valid and applicable.

  8. Scientific Opinion updating the risk assessment conclusions and risk management recommendations on the genetically modified insect resistant maize Bt11

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Genetically Modified Organisms (GMO

    2012-12-01

    Full Text Available Following a request from the European Commission, the Panel on Genetically Modified Organisms of the European Food Safety Authority (EFSA GMO Panel compiled its previous risk assessment conclusions and risk management recommendations on the genetically modified insect resistant maize Bt11, and considered their validity in the light of new relevant scientific publications published from 2005 onwards. Following a search of the scientific literature published between 2005 and October 2012, the EFSA GMO Panel identified 287 peer-reviewed publications containing evidence specific to the risk assessment and/or management of maize Bt11, of which 270 publications were previously discussed and cited in relevant GM maize-related applications and/or the numerous EFSA GMO Panel scientific outputs. From the remaining 17 publications, three were relevant for the food and feed safety assessment, and 14 for the environmental risk assessment and/or risk management of maize Bt11. None of these publications reported new information that would invalidate the previous conclusions on the safety of maize Bt11 made by the EFSA GMO Panel. Therefore, the EFSA GMO Panel considers that its previous risk assessment conclusions on maize Bt11, as well as its previous recommendations on risk mitigation measures and monitoring, remain valid and applicable.

  9. Cosmetics Fact Sheet. To assess the risks for the consumer. Updated version for ConsExpo 4

    NARCIS (Netherlands)

    Bremmer HJ; Prud'homme de Lodder LCH; Engelen JGM van; SIR

    2006-01-01

    Exposure to compounds in consumer products can be assessed using the computer program ConsExpo (Consumer Exposure). Given the huge number of consumer products, it is not possible to calculate the exposure for each separate product, so a limited number of groups containing similar products are define

  10. 76 FR 70076 - Technical Revisions To Update Reference to the Required Assessment Tool for State Nursing Homes...

    Science.gov (United States)

    2011-11-10

    ... Tool for State Nursing Homes Receiving Per Diem Payments From VA AGENCY: Department of Veterans Affairs... diem from VA for providing nursing home care to veterans. The proposed rule would require State nursing... Required Assessment Tool for State Nursing Homes Receiving Per Diem Payments From VA.'' Copies of...

  11. Cosmetics Fact Sheet. To assess the risks for the consumer. Updated version for ConsExpo 4

    NARCIS (Netherlands)

    Bremmer HJ; Prud'homme de Lodder LCH; Engelen JGM van; SIR

    2006-01-01

    Exposure to compounds in consumer products can be assessed using the computer program ConsExpo (Consumer Exposure). Given the huge number of consumer products, it is not possible to calculate the exposure for each separate product, so a limited number of groups containing similar products are

  12. Quantitative Microbial Risk Assessment Tutorial - Navigate the SDMPB and Identify an 8-digit HUC of Interest - Updated 2017

    Science.gov (United States)

    This tutorial reviews some of the screens, icons, and basic functions of the SDMProjectBuilder (SDMPB) that allow a user to identify an 8-digit HUC (HUC-8) of interest from which a pour point or 12-digit HUC (HUC-12) can be chosen for a microbial assessment. It demonstrates how t...

  13. Assessing dangerous climate change through an update of the Intergovernmental Panel on Climate Change (IPCC) “reasons for concern”

    Science.gov (United States)

    Smith, Joel B.; Schneider, Stephen H.; Oppenheimer, Michael; Yohe, Gary W.; Hare, William; Mastrandrea, Michael D.; Patwardhan, Anand; Burton, Ian; Corfee-Morlot, Jan; Magadza, Chris H. D.; Füssel, Hans-Martin; Pittock, A. Barrie; Rahman, Atiq; Suarez, Avelino; van Ypersele, Jean-Pascal

    2009-01-01

    Article 2 of the United Nations Framework Convention on Climate Change [United Nations (1992) http://unfccc.int/resource/docs/convkp/conveng.pdf. Accessed February 9, 2009] commits signatory nations to stabilizing greenhouse gas concentrations in the atmosphere at a level that “would prevent dangerous anthropogenic interference (DAI) with the climate system.” In an effort to provide some insight into impacts of climate change that might be considered DAI, authors of the Third Assessment Report (TAR) of the Intergovernmental Panel on Climate Change (IPCC) identified 5 “reasons for concern” (RFCs). Relationships between various impacts reflected in each RFC and increases in global mean temperature (GMT) were portrayed in what has come to be called the “burning embers diagram.” In presenting the “embers” in the TAR, IPCC authors did not assess whether any single RFC was more important than any other; nor did they conclude what level of impacts or what atmospheric concentrations of greenhouse gases would constitute DAI, a value judgment that would be policy prescriptive. Here, we describe revisions of the sensitivities of the RFCs to increases in GMT and a more thorough understanding of the concept of vulnerability that has evolved over the past 8 years. This is based on our expert judgment about new findings in the growing literature since the publication of the TAR in 2001, including literature that was assessed in the IPCC Fourth Assessment Report (AR4), as well as additional research published since AR4. Compared with results reported in the TAR, smaller increases in GMT are now estimated to lead to significant or substantial consequences in the framework of the 5 “reasons for concern.” PMID:19251662

  14. Assessing dangerous climate change through an update of the Intergovernmental Panel on Climate Change (IPCC) "reasons for concern".

    Science.gov (United States)

    Smith, Joel B; Schneider, Stephen H; Oppenheimer, Michael; Yohe, Gary W; Hare, William; Mastrandrea, Michael D; Patwardhan, Anand; Burton, Ian; Corfee-Morlot, Jan; Magadza, Chris H D; Füssel, Hans-Martin; Pittock, A Barrie; Rahman, Atiq; Suarez, Avelino; van Ypersele, Jean-Pascal

    2009-03-17

    Article 2 of the United Nations Framework Convention on Climate Change [United Nations (1992) http://unfccc.int/resource/docs/convkp/conveng.pdf. Accessed February 9, 2009] commits signatory nations to stabilizing greenhouse gas concentrations in the atmosphere at a level that "would prevent dangerous anthropogenic interference (DAI) with the climate system." In an effort to provide some insight into impacts of climate change that might be considered DAI, authors of the Third Assessment Report (TAR) of the Intergovernmental Panel on Climate Change (IPCC) identified 5 "reasons for concern" (RFCs). Relationships between various impacts reflected in each RFC and increases in global mean temperature (GMT) were portrayed in what has come to be called the "burning embers diagram." In presenting the "embers" in the TAR, IPCC authors did not assess whether any single RFC was more important than any other; nor did they conclude what level of impacts or what atmospheric concentrations of greenhouse gases would constitute DAI, a value judgment that would be policy prescriptive. Here, we describe revisions of the sensitivities of the RFCs to increases in GMT and a more thorough understanding of the concept of vulnerability that has evolved over the past 8 years. This is based on our expert judgment about new findings in the growing literature since the publication of the TAR in 2001, including literature that was assessed in the IPCC Fourth Assessment Report (AR4), as well as additional research published since AR4. Compared with results reported in the TAR, smaller increases in GMT are now estimated to lead to significant or substantial consequences in the framework of the 5 "reasons for concern."

  15. Non-invasive assessment of coronary artery bypass grafts - an update; Koronare Bypassdiagnostik mit CT und MRT - eine Bestandsaufnahme

    Energy Technology Data Exchange (ETDEWEB)

    Kreitner, K.F.; Ehrhard, K.; Kunz, R.P.; Oberholzer, K.; Mildenberger, P.; Thelen, M. [Klinik und Poliklinik fuer Radiologie der Johannes Gutenberg-Univ. Mainz (Germany); Abegunewardene, N.; Horstick, G. [2. Medizinische Klinik und Poliklinik der Johannes Gutenberg-Univ. Mainz (Germany); Hake, U. [Klinik und Poliklinik fuer Herz-Thorax- und Gefaesschirurgie der Johannes Gutenberg-Univ. Mainz (Germany)

    2004-08-01

    The limited lifetime and the correlation between graft occlusion and recurring symptoms underline the need for repeated imaging of coronary artery bypass grafts. CT and MRI allow for noninvasive imaging of coronary bypasses with high accuracies concerning the patency of these vessels. Multidetector CT seem to be the CT technique of choice, especially after the introduction of 16 slice CT scanners for morphologic assessment of coronary artery bypass grafts. Compared with MRI, CT is a robust technique for assessment of cardiac anastomoses, native coronary arteries, anf for the detection of graft stenoses. MRI, however, is able to deliver functional information about the grafts and the recipient coronary arteries by determining the coronary flow reserve. Furthermore, it can be integrated in a multiparametric MR examination protocol. The follow-up of asymptomatic patients can primarily be done by these non-invasive techniques as nearly every third patient reveals an asymptomatic bypass occlusion 5 years after operation. Furthermore, patients with atypical complaints after the operation may undergo non-invasive imaging as long as documented patency of the bypass averts coronary angiography. Patients with recurrent angina pectoris and/or myocardial ischemia discovered by other cardiologic tests have to undergo coronary angiography. (orig.)

  16. Preliminary assessment of the ecological risks to wide-ranging wildlife species on the Oak Ridge Reservation. 1996 update

    Energy Technology Data Exchange (ETDEWEB)

    Sample, B.E.; Hinzman, R.L.; Jackson, B.L.; Baron, L.

    1996-09-01

    More than approximately 50 years of operations, storage, and disposal of wastes generated by the three facilities on the Oak Ridge Reservation (ORR) (the Oak Ridge K-25 Site, Oak Ridge National Laboratory, and the Oak Ridge Y-12 Plant) has resulted in a mosaic of uncontaminated property and lands that are contaminated to varying degrees. This contaminated property includes source areas and the terrestrial and aquatic habitats down gradient from these source areas. Although the integrator OUs generally contain considerable habitat for biota, the source OUs provide little or no suitable habitat. Historically, ecological risk assessment at Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) sites has focused on species that may be definitively associated with a contaminated area or source OU. Endpoints considered in source OUs include plants, soil/litter invertebrates and processes, aquatic biota found in on-OU sediments and surface waters, and small herbivorous, omnivorous, and vermivorous (i.e., feeding on ground, litter, or soil invertebrates) wildlife. All of these endpoints have limited spatial distributions or home ranges such that numerous individuals or a distinct population can be expected to reside within the boundaries of the source OU. Most analyses are not adequate for large sites with multiple, spatially separated contaminated areas such as the ORR that provide habitat for wide-ranging wildlife species. This report is a preliminary response to a plan for assessing risks to wide-ranging species.

  17. Colombia Mi Pronostico Flood Application: Updating and Improving the Mi Pronostico Flood Web Application to Include an Assessment of Flood Risk

    Science.gov (United States)

    Rushley, Stephanie; Carter, Matthew; Chiou, Charles; Farmer, Richard; Haywood, Kevin; Pototzky, Anthony, Jr.; White, Adam; Winker, Daniel

    2014-01-01

    Colombia is a country with highly variable terrain, from the Andes Mountains to plains and coastal areas, many of these areas are prone to flooding disasters. To identify these risk areas NASA's Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) was used to construct a digital elevation model (DEM) for the study region. The preliminary risk assessment was applied to a pilot study area, the La Mosca River basin. Precipitation data from the National Aeronautics and Space Administration (NASA) Tropical Rainfall Measuring Mission (TRMM)'s near-real-time rainfall products as well as precipitation data from the Instituto de Hidrologia, Meteorologia y Estudios Ambientales (the Institute of Hydrology, Meteorology and Environmental Studies, IDEAM) and stations in the La Mosca River Basin were used to create rainfall distribution maps for the region. Using the precipitation data and the ASTER DEM, the web application, Mi Pronóstico, run by IDEAM, was updated to include an interactive map which currently allows users to search for a location and view the vulnerability and current weather and flooding conditions. The geospatial information was linked to an early warning system in Mi Pronóstico that can alert the public of flood warnings and identify locations of nearby shelters.

  18. Neuropsychological test performance of Hawai'i high school athletes: updated Hawai'i immediate post-concussion assessment and cognitive testing data.

    Science.gov (United States)

    Tsushima, William T; Siu, Andrea M

    2014-07-01

    The present study reviewed the Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT) baseline test scores of 247 high school athletes ages 13 to 18 from a private school in Hawai'i. The aim of the research was to update a prior exploratory investigation conducted in 2008 that compared the test scores of Hawai'i public high school athletes with the normative data provided by the ImPACT publishers. The results of this study provide assurance that the present ImPACT scores of the Hawai'i high school athletes are similar to the general ImPACT norms. The present study is a rare effort to compare the ImPACT scores of high school athletes from an ethnically diverse region with the ImPACT norms. The findings offer further support for the use of the ImPACT norms when evaluating high school athletes from Hawai'i. Future research in various regions of the United States and with other sociocultural backgrounds is encouraged.

  19. Regular database update logics

    NARCIS (Netherlands)

    Spruit, Paul; Wieringa, Roel; Meyer, John-Jules

    2001-01-01

    We study regular first-order update logic (FUL), which is a variant of regular dynamic logic in which updates to function symbols as well as to predicate symbols are possible. We fi1rst study FUL without making assumptions about atomic updates. Second, we look at relational algebra update logic (RAU

  20. Varieties of update

    Directory of Open Access Journals (Sweden)

    Sarah E Murray

    2014-03-01

    Full Text Available This paper discusses three potential varieties of update: updates to the common ground, structuring updates, and updates that introduce discourse referents. These different types of update are used to model different aspects of natural language phenomena. Not-at-issue information directly updates the common ground. The illocutionary mood of a sentence structures the context. Other updates introduce discourse referents of various types, including propositional discourse referents for at-issue information. Distinguishing these types of update allows a unified treatment of a broad range of phenomena, including the grammatical evidentials found in Cheyenne (Algonquian as well as English evidential parentheticals, appositives, and mood marking. An update semantics that can formalize all of these varieties of update is given, integrating the different kinds of semantic contributions into a single representation of meaning. http://dx.doi.org/10.3765/sp.7.2 BibTeX info

  1. Updating Parameters for Volcanic Hazard Assessment Using Multi-parameter Monitoring Data Streams And Bayesian Belief Networks

    Science.gov (United States)

    Odbert, Henry; Aspinall, Willy

    2014-05-01

    Evidence-based hazard assessment at volcanoes assimilates knowledge about the physical processes of hazardous phenomena and observations that indicate the current state of a volcano. Incorporating both these lines of evidence can inform our belief about the likelihood (probability) and consequences (impact) of possible hazardous scenarios, forming a basis for formal quantitative hazard assessment. However, such evidence is often uncertain, indirect or incomplete. Approaches to volcano monitoring have advanced substantially in recent decades, increasing the variety and resolution of multi-parameter timeseries data recorded at volcanoes. Interpreting these multiple strands of parallel, partial evidence thus becomes increasingly complex. In practice, interpreting many timeseries requires an individual to be familiar with the idiosyncrasies of the volcano, monitoring techniques, configuration of recording instruments, observations from other datasets, and so on. In making such interpretations, an individual must consider how different volcanic processes may manifest as measureable observations, and then infer from the available data what can or cannot be deduced about those processes. We examine how parts of this process may be synthesised algorithmically using Bayesian inference. Bayesian Belief Networks (BBNs) use probability theory to treat and evaluate uncertainties in a rational and auditable scientific manner, but only to the extent warranted by the strength of the available evidence. The concept is a suitable framework for marshalling multiple strands of evidence (e.g. observations, model results and interpretations) and their associated uncertainties in a methodical manner. BBNs are usually implemented in graphical form and could be developed as a tool for near real-time, ongoing use in a volcano observatory, for example. We explore the application of BBNs in analysing volcanic data from the long-lived eruption at Soufriere Hills Volcano, Montserrat. We discuss

  2. External quality assessment/proficiency testing and internal quality control for the PFA-100 and PFA-200: an update.

    Science.gov (United States)

    Favaloro, Emmanuel J; Bonar, Roslyn

    2014-03-01

    Platelet function testing is an essential component of comprehensive hemostasis evaluation within the framework of bleeding and/or bruising investigations, and it may also be performed to evaluate antiplatelet medication effects. Globally, the platelet function analyzer (PFA)-100 (Siemens Healthcare, Marburg, Germany) is the most used primary hemostasis-screening instrument and has also been recently remodeled/upgraded to the PFA-200. The PFA-100 is sensitive to a wide range of associated disorders, including platelet function defects and von Willebrand disease (VWD), as well as to various antiplatelet medications. The PFA-100 is also useful in therapy monitoring, especially in VWD. External quality assessment (EQA) (or proficiency testing) and internal quality control (IQC) are critical to ensuring quality of test practice, inclusive of all hemostasis tests. However, both EQA and IQC for platelet function testing, including the PFA-100, is logistically challenging, given theoretical requirements for production, storage, and shipment of large volumes of "stabilized" normal and pathological blood/platelets covering both normal function plus a wide variety of potential defects. We accordingly describe the development and testing of novel feasible approaches to both EQA and IQC of PFA-100/PFA-200 instruments, whereby a range of formulated "platelet function antagonist" materials are utilized. For EQA purposes, these are distributed to participants, and citrated normal whole blood collected on site is then added locally, thereby creating test material that can be locally evaluated. Several exercises have been conducted by the Royal College of Pathologists of Australasia Quality Assurance Program (RCPAQAP) over the past 6 years. A total of 26 challenges, with most designed to mimic moderate to severe primary hemostasis defects, have been tested in 26 to 50 laboratories depending on the year of dispatch. Numerical results for PFA-100/PFA-200 closure times (CTs) and

  3. Post-marketing assessment of neuropsychiatric adverse events in influenza patients treated with oseltamivir: an updated review.

    Science.gov (United States)

    Toovey, Stephen; Prinssen, Eric P; Rayner, Craig R; Thakrar, Bharat T; Dutkowski, Regina; Koerner, Annette; Chu, Tom; Sirzen-Zelenskaya, Alexandra; Britschgi, Markus; Bansod, Sudhir; Donner, Barbara

    2012-10-01

    A 2008 review by our group concluded that the risk of neuropsychiatric adverse events (NPAEs) in influenza patients was not increased by oseltamivir exposure, and did not identify any mechanism by which oseltamivir or its metabolites could cause or worsen such events. The current article reviews new information on this topic. Between September 16, 2007 and May 15, 2010, 1,805 spontaneously-reported NPAEs were identified in 1,330 patients receiving oseltamivir: 767 (42.5%) from Japan, 296 (16.4%) from the USA, and 742 (41.1%) from other countries. NPAEs were more common in children: 1,072 (59.4%) events were in those aged ≤16 years. NPAEs often occurred within 48 h of treatment initiation (953 events; 52.8%). Nearly half of the events were serious in nature (838; 46.4%). The three largest categories of events were abnormal behavior (457 events, 25.3%), miscellaneous psychiatric events (370; 20.5%), and delusions/perceptual disturbances (316 events, 17.5%). A total of 1,545 events (85.6%) in eight different categories were considered to be delirium or delirium-like. Twenty-eight suicide-related events were reported. A US healthcare claims database analysis showed that the risk of NPAEs in 7,798 oseltamivir-treated patients was no higher than that in 10,411 patients not on antivirals, but a study on oseltamivir and abnormal behavior in Japan was less conclusive. NPAE frequency in oseltamivir-exposed Japanese and Taiwanese children with influenza was the same as in unexposed children. New analysis of the UK General Practice Research Database showed that the relative adjusted risk of NPAEs in influenza patients was 2.18-times higher than in the general population. Other epidemiology studies report frequent occurrence of encephalitis and similar disorders in influenza patients independently of oseltamivir exposure. The new data support the findings of the original assessment. Evidence suggests that influenza-related encephalopathies are caused by influenza

  4. Key skills by design: adapting a central Web resource to departmental contexts

    Directory of Open Access Journals (Sweden)

    Claire McAvinia

    2002-12-01

    Full Text Available Web-based delivery of support materials for students has proved to be a popular way of helping small teams to implement key skills policies within universities. The development of 'key' or 'transferable' skills is now encouraged throughout education, but resources (both in terms of staffing and budget tend to be limited. It is difficult for key skills teams to see learners face to face, and not feasible to print or distribute large amounts of paper-based material. Web-based delivery presents a means of overcoming these problems but it can result in generic study skills material simply being published online without due consideration of the needs of different groups of learners within different subject disciplines. Therefore, although a centralized Website for skills provision can overcome logistical problems, it may be perceived as irrelevant or unusable by the student population. This paper presents a model for Web-based delivery of support for key skills which incorporates two separate approaches to the design of these resources. The model was implemented as part of a wider key skills pilot project at University College London, over a period of one year. It includes a 'core' Website, containing information and resources for staff and students. These can also be accessed via customized, departmental key skills homepages. This paper presents the basis for the design choices made in preparing these materials, and the evaluation of some of the pilot departments using them. It then draws some wider conclusions about the effectiveness of this design for supporting skills development.

  5. 40 CFR 68.36 - Review and update.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 15 2010-07-01 2010-07-01 false Review and update. 68.36 Section 68.36... ACCIDENT PREVENTION PROVISIONS Hazard Assessment § 68.36 Review and update. (a) The owner or operator shall review and update the offsite consequence analyses at least once every five years. (b) If changes...

  6. An update on UK rheumatology consultant workforce provision: the BSR/ARC Workforce Register 2005–07: assessing the impact of recent changes in NHS provision

    Science.gov (United States)

    Harrison, M. J.; Deighton, C.

    2008-01-01

    Objectives. To describe changes in the provision of rheumatology services, monitor the pattern of inequalities in UK rheumatology service provision since 2005, and to summarize the 3-yr impact of the new National Health Service (NHS) consultant contract and the Musculoskeletal Services Framework in England and Wales. Methods. Questionnaires about timetable and working conditions were sent to all consultants on the BSR/ARC UK Workforce Register in January 2007, along with the personal and job-related details currently held about them on the register to update. The questionnaire included a visual analogue scale asking ‘how concerned are you that your current post might be under threat’ ranging from 0 ‘Not at all’ to 100 ‘Extremely’. Results. The response rate of the 2005 and 2007 surveys were 89 and 87%, respectively. Levels of optimal provision now exceed 70% in England and Wales, and 50% in Scotland and Northern Ireland. Levels of provision remain substantially higher in London than anywhere else. The median level of perceived job threat in the UK was 31 (interquartile range 11–61). Consultants in areas where provision is highest and a higher proportion of services are run in conjunction with Clinical Assessment and Treatment (CAT) centres report higher perceived job threat. Conclusions. Provision of rheumatology services has continued to expand over the past decade; however, inequalities persist at national and sub-national level. There is evidence of improvement in regions with the lowest provision, but there are indications of increased perceived job threat in areas with traditionally higher provision and where CAT centres have been introduced. PMID:18424468

  7. Updated defense display market assessment

    Science.gov (United States)

    Desjardins, Daniel D.; Hopper, Darrel G.

    1999-08-01

    This paper addresses the number, function and size of principal military displays and establishes a basis to determine the opportunities for technology insertion in the immediate future and into the next millennium. Principal military displays are defined as those occupying appreciable crewstation real-estate and/or those without which the platform could not carry out its intended mission. DoD 'office' applications are excluded from this study. The military displays market is specified by such parameters as active area and footprint size, and other characteristics such as luminance, gray scale, resolution, angle, color, video capability, and night vision imaging system compatibility. Funded, future acquisitions, planned and predicted crewstation modification kits, and form-fit upgrades are taken into account. This paper provides an overview of the DoD niche market, allowing both government and industry a necessary reference by which to meet DoD requirements for military displays in a timely and cost-effective manner. The aggregate DoD installed base for direct-view and large-area military displays is presently estimated to be in excess of 313,000. Miniature displays are those which must be magnified to be viewed, involve a significantly different manufacturing paradigm and are used in helmet mounted displays and thermal weapon sight applications. Some 114,000 miniature displays are presently included within future weapon system acquisition plans. For vendor production planning purposes it is noted that foreign military sales could substantially increase these quantities. The vanishing vendor syndrome (VVS) for older display technologies continues to be a growing, pervasive problem throughout DoD, which consequently must leverage the more modern, especially flat panel, display technologies being developed to replace older, especially cathode ray tube, technology for civil-commercial markets. Total DoD display needs (FPD, HMD) are some 427,000.

  8. Beyond the EPR: Complementary roles of the hospital-wide electronic health record and clinical departmental systems

    Science.gov (United States)

    2009-01-01

    Background Many hospital departments have implemented small clinical departmental systems (CDSs) to collect and use patient data for documentation as well as for other department-specific purposes. As hospitals are implementing institution-wide electronic patient records (EPRs), the EPR is thought to be integrated with, and gradually substitute the smaller systems. Many EPR systems however fail to support important clinical workflows. Also, successful integration of systems has proven hard to achieve. As a result, CDSs are still in widespread use. This study was conducted to see which tasks are supported by CDSs and to compare this to the support offered by the EPR. Methods Semi-structured interviews with users of 16 clinicians using 15 different clinical departmental systems (CDS) at a Medium-sized University hospital in Norway. Inductive analysis of transcriptions from the audio taped interviews. Results The roles of CDSs were complementary to those of the hospital-wide EPR system. The use of structured patient data was a characteristic feature. This facilitated quality development and supervision, tasks that were poorly supported by the EPR system. The structuring of the data also improved filtering of information to better support clinical decision-making. Because of the high value of the structured patient data, the users put much effort in maintaining their integrity and representativeness. Employees from the departments were also engaged in the funding, development, implementation and maintenance of the systems. Conclusion Clinical departmental systems are vital to the activities of a clinical hospital department. The development, implementation and clinical use of such systems can be seen as bottom-up, user-driven innovations. PMID:19523198

  9. Breast Cancer Research Update

    Science.gov (United States)

    ... JavaScript on. Feature: Breast Cancer Breast Cancer Research Update Winter 2017 Table of Contents National Cancer Institute ... Addressing Breast Cancer's Unequal Burden / Breast Cancer Research Update Winter 2017 Issue: Volume 11 Number 4 Page ...

  10. Keeping Updated

    DEFF Research Database (Denmark)

    Reading, David; Botjes, Erna; Nørhede, Pia

    2013-01-01

    Knowledge of food allergy is constantly developing. The food industry makes decisions based on what is currently known, but there is a need to remain at the forefront of understanding so that actions taken by the industry are not outdated and are of maximum benefit to food allergic consumers....... The best way to stay up to date is via the Internet. There are numerous websites that fulfill this function, including those run by regulatory bodies, scientific organizations, and groups whose specific objective is to provide industry with helpful information to assist with the assessment and management...

  11. Departmental plans of domestic wastes management - evaluation 2002; Plans departementaux d'elimination des dechets menager assimiles - bilan 2002

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-03-01

    The departmental plans of domestic wastes management are official documents which manage the actions needed to realize the legislative and regulation objectives concerning the domestic wastes and related wastes. A first evaluation has been realized in 1997 for 47 edited plans. In the context of the new wastes policy a new evaluation has been realized by the ADEME in 2002 for 98 plans. It provides the methodology of the study, the analysis of the plans, the sites and management of wastes, economic data, the equipment and investments. (A.L.B.)

  12. [The quantitative estimates of identification of diseases in medical institutions of different form of property and departmental belonging].

    Science.gov (United States)

    Maksimova, T M; Belov, V B; Lushkina, N P; Nikitina, S Yu; Redina, M A

    2013-01-01

    The results of analysis of actual situation in the field of medical care provision to population by medical institutions of different form of property and departmental belonging demonstrated that the percentage of additionally identified cases of pathology of blood circulation system comes up to 20% and more in certain territories. This occurrence mainly depends on organization of medical care of population in the field and development of medical institutions network outside the system of Minzdrav of Russia. It is needed to further elaborate the process of getting the data specifying the statistics of pathology propagation.

  13. The Assessment of Atmospheric Correction Processors for MERIS Based on In-Situ Measurements-Updates in OC-CCI Round Robin

    Science.gov (United States)

    Muller, Dagmar; Krasemann, Hajo; Zuhilke, Marco; Doerffer, Roland; Brockmann, Carsten; Steinmetz, Francois; Valente, Andre; Brotas, Vanda; Grant, kMicheal G.; Sathyendranath, Shubha; Melin, Frederic; Franz, Bryan A.; Mazeran, Constant; Regner, Peter

    2016-08-01

    The Ocean Colour Climate Change Initiative (OC- CCI) provides a long-term time series of ocean colour data and investigates the detectable climate impact. A reliable and stable atmospheric correction (AC) procedure is the basis for ocean colour products of the necessary high quality.The selection of atmospheric correction processors is repeated regularly based on a round robin exercise, at the latest when a revised production and release of the OC-CCI merged product is scheduled. Most of the AC processors are under constant development and changes are implemented to improve the quality of satellite-derived retrievals of remote sensing reflectances. The changes between versions of the inter-comparison are not restricted to the implementation of AC processors. There are activities to improve the quality flagging for some processors, and the system vicarious calibration for AC algorithms in their sensor specific behaviour are widely studied. Each inter-comparison starts with an updated in-situ database, as more spectra are included in order to broaden the temporal and spatial range of satellite match-ups. While the OC-CCI's focus has laid on case-1 waters in the past, it has expanded to the retrieval of case-2 products now. In light of this goal, new bidirectional correction procedures (normalisation) for the remote sensing spectra have been introduced. As in-situ measurements are not always available at the satellite sensor specific central wave- lengths, a band-shift algorithm has to be applied to the dataset.In order to guarantee an objective selection from a set of four atmospheric correction processors, the common validation strategy of comparisons between in-situ and satellite-derived water leaving reflectance spectra, is aided by a ranking system. In principal, the statistical parameters are transformed into relative scores, which evaluate the relationship of quality dependent on the algorithms under study. The sensitivity of these scores to the selected

  14. [Retinoblastoma update].

    Science.gov (United States)

    Aerts, I; Lumbroso-Le Rouic, L; Gauthier-Villars, M; Brisse, H; Doz, F

    2016-01-01

    Retinoblastoma is the most common intraocular malignancy of infancy with an incidence of 1/15,000 births. Sixty percent of retinoblastomas are unilateral, with a median age at diagnosis of 2 years, and in most cases they are not hereditary. Retinoblastoma is bilateral in 40% of cases, with an earlier median age at diagnosis of 1 year. All bilateral and multifocal unilateral forms are hereditary and are part of a genetic cancer predisposition syndrome. All children with a bilateral or familial form, and 10-15% of children with a unilateral form, constitutionally carry an RB1 gene mutation. The two most frequent symptoms at diagnosis are leukocoria and strabismus. Diagnosis is made by fundoscopy, with ultrasound and magnetic resonance imaging (MRI) contributing both to diagnosis and assessment of the extension of the disease. Treatment of patients with retinoblastoma must take into account the various aspects of the disease (unilateral/bilateral, size, location), the risks for vision, and the possible hereditary nature of the disease. The main prognostic aspects are still early detection and adapted coverage by a multidisciplinary, highly specialized team. Enucleation is still often necessary in unilateral disease; the decision for adjuvant treatment is made according to the histological risk factors. The most important recent therapeutic advances concern conservative treatment, which is proposed for at least one of the two eyes in most bilateral cases: laser alone or in combination with chemotherapy, cryotherapy, or brachytherapy. Recently, the development of new conservative techniques of treatment, such as intra-arterial selective chemotherapy perfusion and intravitreal injections, aims at preserving visual function in these children and decreasing the number of enucleations and the need for external beam radiotherapy. The vital prognosis related to retinoblastoma is now excellent in industrialized countries, but long-term survival is still related to the

  15. Systematic review on tuberculosis transmission on aircraft and update of the European Centre for Disease Prevention and Control risk assessment guidelines for tuberculosis transmitted on aircraft (RAGIDA-TB).

    Science.gov (United States)

    Kotila, Saara M; Payne Hallström, Lara; Jansen, Niesje; Helbling, Peter; Abubakar, Ibrahim

    2016-01-01

    As a setting for potential tuberculosis (TB) transmission and contact tracing, aircraft pose specific challenges. Evidence-based guidelines are needed to support the related-risk assessment and contact-tracing efforts. In this study evidence of TB transmission on aircraft was identified to update the Risk Assessment Guidelines for TB Transmitted on Aircraft (RAGIDA-TB) of the European Centre for Disease Prevention and Control (ECDC). Electronic searches were undertaken from Medline (Pubmed), Embase and Cochrane Library until 19 July 2013. Eligible records were identified by a two-stage screening process and data on flight and index case characteristics as well as contact tracing strategies extracted. The systematic literature review retrieved 21 records. Ten of these records were available only after the previous version of the RAGIDA guidelines (2009) and World Health Organization guidelines on TB and air travel (2008) were published. Seven of the 21 records presented some evidence of possible in-flight transmission, but only one record provided substantial evidence of TB transmission on an aircraft. The data indicate that overall risk of TB transmission on aircraft is very low. The updated ECDC guidelines for TB transmission on aircraft have global implications due to inevitable need for international collaboration in contract tracing and risk assessment.

  16. Updated study reporting levels (SRLs) for trace-element data collected for the California Groundwater Ambient Monitoring and Assessment (GAMA) Priority Basin Project, October 2009-March 2013

    Science.gov (United States)

    Davis, Tracy A.; Olsen, Lisa D.; Fram, Miranda S.; Belitz, Kenneth

    2014-01-01

    Groundwater samples have been collected in California as part of statewide investigations of groundwater quality conducted by the U.S. Geological Survey for the Groundwater Ambient Monitoring and Assessment (GAMA) Priority Basin Project (PBP). The GAMA-PBP is being conducted in cooperation with the California State Water Resources Control Board to assess and monitor the quality of groundwater resources used for drinking-water supply and to improve public knowledge of groundwater quality in California. Quality-control samples (source-solution blanks, equipment blanks, and field blanks) were collected in order to ensure the quality of the groundwater sample results. Olsen and others (2010) previously determined study reporting levels (SRLs) for trace-element results based primarily on field blanks collected in California from May 2004 through January 2008. SRLs are raised reporting levels used to reduce the likelihood of reporting false detections attributable to contamination bias. The purpose of this report is to identify any changes in the frequency and concentrations of detections in field blanks since the last evaluation and update the SRLs for more recent data accordingly. Constituents analyzed were aluminum (Al), antimony (Sb), arsenic (As), barium (Ba), beryllium (Be), boron (B), cadmium (Cd), chromium (Cr), cobalt (Co), copper (Cu), iron (Fe), lead (Pb), lithium (Li), manganese (Mn), molybdenum (Mo), nickel (Ni), selenium (Se), silver (Ag), strontium (Sr), thallium (Tl), tungsten (W), uranium (U), vanadium (V), and zinc (Zn). Data from 179 field blanks and equipment blanks collected from March 2006 through March 2013 by the GAMA-PBP indicated that for trace elements that had a change in detection frequency and concentration since the previous review, the shift occurred near October 2009, in conjunction with a change in the capsule filters used by the study. Results for 89 field blanks and equipment blanks collected from October 2009 through March 2013 were

  17. Administrative Strategies of Departmental Heads as Determinants for the Effective Management of Human Resources in Tertiary Institutions in Delta State, Nigeria

    Science.gov (United States)

    Osakwe, Regina N.

    2015-01-01

    This study investigated administrative strategies of departmental heads as determinants of effective management of human resources in tertiary institutions. Four research questions were asked and four hypotheses were formulated to guide the study. As a descriptive survey, the population comprised all the eight tertiary institutions in the state…

  18. The Molecular Biology Capstone Assessment: A Concept Assessment for Upper-Division Molecular Biology Students

    Science.gov (United States)

    Couch, Brian A.; Wood, William B.; Knight, Jennifer K.

    2015-01-01

    Measuring students' conceptual understandings has become increasingly important to biology faculty members involved in evaluating and improving departmental programs. We developed the Molecular Biology Capstone Assessment (MBCA) to gauge comprehension of fundamental concepts in molecular and cell biology and the ability to apply these concepts in…

  19. Cementitious near-field sorption data bases for performance assessment of a L/ILW repository in a Palfris marl host rock. CEM-94: update I, June 1997

    Energy Technology Data Exchange (ETDEWEB)

    Bradbury, M.H.; Loon, L.R. van [Paul Scherrer Inst. (PSI), Villigen (Switzerland)

    1998-01-01

    This report is an update on an earlier cementitious sorption data base (SDB) prepared by Bradbury and Sarott (1994). The aim is to review any new information or data which have become available in the intervening time and modify the existing SDB appropriately. Discussions will be confined predominantly to areas which have led to significant changes to or reappraisals of the data/values or procedures for obtaining/modifying them. From this point of view this update and the previous SDB are closely related and belong together. The complexation of radionuclides with organic ligands from the chemical degradation of cellulose, and the subsequent negative effects on sorption properties, were identified as being processes of great importance. Since 1994 significant progress has been made in this field and a major part of this work is devoted to a reassessment of the impact of `organics` on near-field sorption. In particular, the very conservative assumptions which had been made previously because of the general lack of good quality data available at that time, could be replaced by realistic parameter estimates based on new knowledge. For example, maximum likely concentrations of cellulose degradation products and cement additives in the cement pore waters could be calculated allowing the potential effects of these organic ligands on sorption to be bounded. Sorption values for safety relevant radionuclides corresponding to the three broad stages of cement/concrete degradation during the lifetime of the repository are presented in tabulated form. The influence of the wide variety of organic ligands existing in the different waste categories, SMA-1 to SMA-4, is quantified in terms of sorption reduction factors. In the compilation of this cement SDB update, radionuclide uptake onto the vast quantities of aggregate materials and corrosion products from iron/steel was not taken into account. (author) 10 figs., 8 tabs., refs.

  20. Country Update: Israel 2005

    Science.gov (United States)

    Marar, Marianne Maurice

    2005-01-01

    Country Updates is a new section of "Intercultural Education." Starting in "Intercultural Education," Volume 16 No. 5, this column will focus on recent developments during the last two to three years in the field of intercultural education in one particular country. These updates can include recent policy decisions, the main…

  1. Updated Strategic Assessment of the U.S. NRC Low-Level Radioactive Waste (LLW) Program and the new WCS Commercial Disposal Facility for LLW

    Energy Technology Data Exchange (ETDEWEB)

    Kessel, David S.; Kim, Chang-Lak [KEPCO International Nuclear Graduate School, Ulsan (Korea, Republic of)

    2015-05-15

    The purpose of this paper is to review the updated NRC low level radioactive waste regulatory strategy and also present an update on a significant change in the LLW disposal landscape in the U.S., the opening of a new commercial disposal facility, the Texas Compact Waste Facility (CWF) in Andrews, Texas. Operational since spring of 2012, the CWF is owned and licensed by the state of Texas and operated by Waste Control Specialists LLC (WCS). The WCS facility in western Andrews County is the only commercial facility in the United States licensed to dispose of Class A, B and C LLW in the U.S. in the past 40 years. Based on the observation that other suitable sites have been identified such as the Clive, Utah site that meet (almost) all of these criteria it would appear that the first and last factors in our list are the most problematic and it will require a change in the public acceptance and the political posture of states to help solve the national issue of safe and cost-effective LLW disposal.

  2. Update in Internal Medicine

    Science.gov (United States)

    López-Jiménez, Francisco; Brito, Máximo; Aude, Y. Wady; Scheinberg, Phillip; Kaplan, Mariana; Dixon, Denise A.; Schneiderman, Neil; Trejo, Jorge F.; López-Salazar, Luis Humberto; Ramírez-Barba, Ector Jaime; Kalil, Roberto; Ortiz, Carmen; Goyos, José; Buenaño, Alvaro; Kottiech, Samer; Lamas, Gervasio A.

    2009-01-01

    More than 500,000 new medical articles are published every year and available time to keep updated is scarcer every day. Nowadays, the task of selecting useful, consistent, and relevant information for clinicians is a priority in many major medical journals. This review has the aim of gathering the results of the most important findings in clinical medicine in the last few years. It is focused on results from randomized clinical trials and well-designed observational research. Findings were included preferentially if they showed solid results, and we avoided as much as possible including only preliminary data, or results that included only non-clinical outcomes. Some of the most relevant findings reported here include the significant benefit of statins in patients with coronary artery disease even with mean cholesterol level. It also provides a substantial review of the most significant trials assessing the effectiveness of IIb/IIIa receptor blockers. In gastroenterology many advances have been made in the H. pylori eradication, and the finding that the cure of H. pylori infection may be followed by gastroesophageal reflux disease. Some new antivirals have shown encouraging results in patients with chronic hepatitis. In the infectious disease arena, the late breaking trials in anti-retroviral disease are discussed, as well as the new trends regarding antibiotic resistance. This review approaches also the role of leukotriene modifiers in the treatment of asthma and discusses the benefit of using methylprednisolone in patients with adult respiratory distress syndrome, among many other advances in internal medicine. PMID:11068074

  3. The hydrobioid freshwater gastropods (Caenogastropoda, Truncatelloidea of Greece: new records, taxonomic re-assessments using DNA sequence data and an update of the IUCN Red List Categories

    Directory of Open Access Journals (Sweden)

    Canella Radea

    2013-11-01

    Full Text Available Hydrobioid freshwater gastropods were collected from mainland and insular Greece. Several threatened taxa, such as Graecoanatolica vegorriticola, Pseudamnicola negropontina, Pseudamnicola pieperi, Pseudobithynia eubooensis and Pseudoislamia balcanica, were recorded from new localities. Trichonia trichonica, which has been considered extinct from its type locality for the last twenty eight years, was re-discovered, whereas the presence of Daphniola exigua, G. vegorriticola, Marstoniopsis graeca, P. pieperi and Pseudobithynia trichonis in their type localities was verified. The taxonomic status of P. negropontina and the newly discovered populations of G. vegorriticola was elucidated using COI sequence data. The new data recorded during this survey indicate that the IUCN status of some Greek endemic hydrobioids needs to be updated.

  4. eBASIS (Bioactive Substances in Food Information Systems) and Bioactive Intakes: Major Updates of the Bioactive Compound Composition and Beneficial Bioeffects Database and the Development of a Probabilistic Model to Assess Intakes in Europe.

    Science.gov (United States)

    Plumb, Jenny; Pigat, Sandrine; Bompola, Foteini; Cushen, Maeve; Pinchen, Hannah; Nørby, Eric; Astley, Siân; Lyons, Jacqueline; Kiely, Mairead; Finglas, Paul

    2017-03-23

    eBASIS (Bioactive Substances in Food Information Systems), a web-based database that contains compositional and biological effects data for bioactive compounds of plant origin, has been updated with new data on fruits and vegetables, wheat and, due to some evidence of potential beneficial effects, extended to include meat bioactives. eBASIS remains one of only a handful of comprehensive and searchable databases, with up-to-date coherent and validated scientific information on the composition of food bioactives and their putative health benefits. The database has a user-friendly, efficient, and flexible interface facilitating use by both the scientific community and food industry. Overall, eBASIS contains data for 267 foods, covering the composition of 794 bioactive compounds, from 1147 quality-evaluated peer-reviewed publications, together with information from 567 publications describing beneficial bioeffect studies carried out in humans. This paper highlights recent updates and expansion of eBASIS and the newly-developed link to a probabilistic intake model, allowing exposure assessment of dietary bioactive compounds to be estimated and modelled in human populations when used in conjunction with national food consumption data. This new tool could assist small- and medium-sized enterprises (SMEs) in the development of food product health claim dossiers for submission to the European Food Safety Authority (EFSA).

  5. Extending the assessment of patient-centredness in health care: Development of the updated Valuing Patients as Individuals Scale using exploratory factor analysis.

    Science.gov (United States)

    Jones, Martyn C; Williams, Brian; Rattray, Janice; MacGillivray, Steve; Baldie, Debbie; Abubakari, Abdul-Razak; Coyle, Joanne; Mackie, Susan; McKenna, Eileen

    2017-04-12

    To update and re-validate the Valuing Patients as Individuals Scale for use as a patient appraisal of received healthcare. Healthcare in the United Kingdom and beyond is required to deliver high quality, person-centred care that is clinically effective and safe. However, patient experience is not uniform, and complaints often focus on the way patients have been treated. Legislation in United Kingdom requires health services to gather and use patients' evaluations of care to improve services. This study uses scoping literature reviews, cognitive testing of questionnaire items with patient and healthcare staff focus groups, and exploratory factor analysis. Data were collected from 790 participants across 34 wards in two acute hospitals in one National Health Service Health Board in Scotland from September 2011-February 2012. Ethics and Research and Development approval were obtained. Fifty six unique items identified through literature review were added to 72 original Valuing Patients as Individuals Scale items. Face validity interviews removed ambiguous or low relevance items leaving 88 items for administration to patients. Two hundred and ninety questionnaires were returned, representing 37% response rate, 71 were incomplete. Thus 219 complete data were used for Exploratory Factor Analysis with varimax orthogonal rotation. This revealed a 31 item, three factor solution, Care and Respect; Understanding and Engagement; Patient Concerns, with good reliability, concurrent and discriminant validity in terms of gender. A shortened 10 item measure based on the top 3 or 4 loading items on each scale was comparable. The Updated Valuing Patients as Individuals Scale is sufficiently developed to capture patient appraisals of received care. The short scale version is now being routinized in real-time evaluation of patient experience contributing to this United Kingdom, National Health Service setting meeting its policy and legislative requirements. © 2017 John Wiley & Sons

  6. ACS Updates Environmental Report.

    Science.gov (United States)

    Chemical and Engineering News, 1978

    1978-01-01

    Describes a new publication of a report prepared by the American Chemical Society's Committee on Environmental Improvement. This is a new version that updates a 1969 report and contains additional material and expanded recommendations. (GA)

  7. Veterinary medicines update.

    Science.gov (United States)

    2017-03-11

    The following information has been produced for Veterinary Record by the Veterinary Medicines Directorate (VMD) to provide an update for veterinary surgeons on recent changes to marketing authorisations for veterinary medicines in the UK and on other relevant issues.

  8. ACS Updates Environmental Report.

    Science.gov (United States)

    Chemical and Engineering News, 1978

    1978-01-01

    Describes a new publication of a report prepared by the American Chemical Society's Committee on Environmental Improvement. This is a new version that updates a 1969 report and contains additional material and expanded recommendations. (GA)

  9. Los Alamos Climatology 2016 Update

    Energy Technology Data Exchange (ETDEWEB)

    Bruggeman, David Alan [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-02-10

    The Los Alamos National Laboratory (LANL or the Laboratory) operates a meteorology monitoring network to support LANL emergency response, engineering designs, environmental compliance, environmental assessments, safety evaluations, weather forecasting, environmental monitoring, research programs, and environmental restoration. Weather data has been collected in Los Alamos since 1910. Bowen (1990) provided climate statistics (temperature and precipitation) for the 1961– 1990 averaging period, and included other analyses (e.g., wind and relative humidity) based on the available station locations and time periods. This report provides an update to the 1990 publication Los Alamos Climatology (Bowen 1990).

  10. 75 FR 5317 - Exposure Factors Handbook: 2009 Update

    Science.gov (United States)

    2010-02-02

    ... AGENCY Exposure Factors Handbook: 2009 Update AGENCY: Environmental Protection Agency (EPA). ACTION... draft document titled, ``Exposure Factors Handbook 2009 Update'' (EPA/600/R- 09/052A). EPA previously... Environmental Assessment (NCEA) within EPA's Office of Research and Development. The Exposure Factors Handbook...

  11. The Form is the Bottom Line, Yes, But Sometimesthe Bottom Line Alters the Form: A Reflection on the Departmental Process at UAM

    Directory of Open Access Journals (Sweden)

    Manuel Gil Antón

    2005-05-01

    Full Text Available In this work the departmental organization at higher education institutions is commented, not as a –better or worse– plan with upper intrinsic values, but as an organizational structure that, depending on its purpose, can offer an opportunity or excuses for organizational change. The experience of the Metropolitan Autonomous University is described (UAM, Mexico, as an institution that since its origin was born with a departmental structure and with a dot-matrix service of its departments. This work offers data of the first 13 years of life (1974-1987 of the Department of Sociology in UAM, at Azcapotzalco, as a sample of this kind of system. In the example, general characteristics of age, working conditions al income, academic degree al income, institution where were formed and their labor antecedents are shown. Also, the difficulties faced initially by the educators of this institution, due to their youth, are described; as well as the nostalgia of some departments about adopting traditional systems, used in practice. This is a work that offers suggestions for educational institutions who are interested in adopting the departmental model.

  12. Fisher: a program for the detection of H/ACA snoRNAs using MFE secondary structure prediction and comparative genomics – assessment and update

    Science.gov (United States)

    Freyhult, Eva; Edvardsson, Sverker; Tamas, Ivica; Moulton, Vincent; Poole, Anthony M

    2008-01-01

    Background The H/ACA family of small nucleolar RNAs (snoRNAs) plays a central role in guiding the pseudouridylation of ribosomal RNA (rRNA). In an effort to systematically identify the complete set of rRNA-modifying H/ACA snoRNAs from the genome sequence of the budding yeast, Saccharomyces cerevisiae, we developed a program – Fisher – and previously presented several candidate snoRNAs based on our analysis [1]. Findings In this report, we provide a brief update of this work, which was aborted after the publication of experimentally-identified snoRNAs [2] identical to candidates we had identified bioinformatically using Fisher. Our motivation for revisiting this work is to report on the status of the candidate snoRNAs described in [1], and secondly, to report that a modified version of Fisher together with the available multiple yeast genome sequences was able to correctly identify several H/ACA snoRNAs for modification sites not identified by the snoGPS program [3]. While we are no longer developing Fisher, we briefly consider the merits of the Fisher algorithm relative to snoGPS, which may be of use for workers considering pursuing a similar search strategy for the identification of small RNAs. The modified source code for Fisher is made available as supplementary material. Conclusion Our results confirm the validity of using minimum free energy (MFE) secondary structure prediction to guide comparative genomic screening for RNA families with few sequence constraints. PMID:18710502

  13. Land and Water Use Characteristics and Human Health Input Parameters for use in Environmental Dosimetry and Risk Assessments at the Savannah River Site 2017 Update

    Energy Technology Data Exchange (ETDEWEB)

    Jannik, T. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Stagich, B. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2017-05-25

    Operations at the Savannah River Site (SRS) result in releases of relatively small amounts of radioactive materials to the atmosphere and to the Savannah River. For regulatory compliance purposes, potential offsite radiological doses are estimated annually using computer models that follow U.S. Nuclear Regulatory Commission (NRC) regulatory guides. Within the regulatory guides, default values are provided for many of the dose model parameters, but the use of site-specific values is encouraged. Detailed surveys of land-use and water-use parameters were conducted in 1991, 2008, 2010, and 2016 and are being concurred with or updated in this report. These parameters include local characteristics of meat, milk, and vegetable production; river recreational activities; and meat, milk, and vegetable consumption rates, as well as other human usage parameters required in the SRS dosimetry models. In addition, the preferred elemental bioaccumulation factors and transfer factors (to be used in human health exposure calculations at SRS) are documented. The intent of this report is to establish a standardized source for these parameters that is up to date with existing data, and that is maintained via review of future-issued national references (to evaluate the need for changes as new information is released). These reviews will continue to be added to this document by revision.

  14. Land and Water Use Characteristics and Human Health Input Parameters for use in Environmental Dosimetry and Risk Assessments at the Savannah River Site. 2016 Update

    Energy Technology Data Exchange (ETDEWEB)

    Jannik, G. Tim [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Hartman, Larry [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Stagich, Brooke [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2016-09-26

    Operations at the Savannah River Site (SRS) result in releases of small amounts of radioactive materials to the atmosphere and to the Savannah River. For regulatory compliance purposes, potential offsite radiological doses are estimated annually using computer models that follow U.S. Nuclear Regulatory Commission (NRC) regulatory guides. Within the regulatory guides, default values are provided for many of the dose model parameters, but the use of applicant site-specific values is encouraged. Detailed surveys of land-use and water-use parameters were conducted in 1991 and 2010. They are being updated in this report. These parameters include local characteristics of meat, milk and vegetable production; river recreational activities; and meat, milk and vegetable consumption rates, as well as other human usage parameters required in the SRS dosimetry models. In addition, the preferred elemental bioaccumulation factors and transfer factors (to be used in human health exposure calculations at SRS) are documented. The intent of this report is to establish a standardized source for these parameters that is up to date with existing data, and that is maintained via review of future-issued national references (to evaluate the need for changes as new information is released). These reviews will continue to be added to this document by revision.

  15. Development of departmental standard for traceability of measured activity for I-131 therapy capsules used in nuclear medicine

    Directory of Open Access Journals (Sweden)

    Ravichandran Ramamoorthy

    2011-01-01

    Full Text Available International Basic Safety Standards (International Atomic Energy Agency, IAEA provide guidance levels for diagnostic procedures in nuclear medicine indicating the maximum usual activity for various diagnostic tests in terms of activities of injected radioactive formulations. An accuracy of ± 10% in the activities of administered radio-pharmaceuticals is being recommended, for expected outcome in diagnostic and therapeutic nuclear medicine procedures. It is recommended that the long-term stability of isotope calibrators used in nuclear medicine is to be checked periodically for their performance using a long-lived check source, such as Cs-137, of suitable activity. In view of the un-availability of such a radioactive source, we tried to develop methods to maintain traceability of these instruments, for certifying measured activities for human use. Two re-entrant chambers [(HDR 1000 and Selectron Source Dosimetry System (SSDS] with I-125 and Ir-192 calibration factors in the Department of Radiotherapy were used to measure Iodine-131 (I-131 therapy capsules to establish traceability to Mark V isotope calibrator of the Department of Nuclear Medicine. Special nylon jigs were fabricated to keep I-131 capsule holder in position. Measured activities in all the chambers showed good agreement. The accuracy of SSDS chamber in measuring Ir-192 activities in the last 5 years was within 0.5%, validating its role as departmental standard for measuring activity. The above method is adopted because mean energies of I-131 and Ir-192 are comparable.

  16. "Platooning" Instruction: Districts Weigh Pros and Cons of Departmentalizing Elementary Schools

    Science.gov (United States)

    Hood, Lucy

    2010-01-01

    To platoon or not to platoon? That's the question facing Irving Hamer, Deputy Superintendent of Academic Operations, Technology and lnnovation for the Memphis City Schools. This year for the first time, the state's achievement test, Tennessee Comprehensive Assessment Program (TCAP), will include algebraic concepts on the 5th-grade test. Of the…

  17. Assessing the Greenness of Chemical Reactions in the Laboratory Using Updated Holistic Graphic Metrics Based on the Globally Harmonized System of Classification and Labeling of Chemicals

    Science.gov (United States)

    Ribeiro, M. Gabriela T. C.; Yunes, Santiago F.; Machado, Adelio A. S. C.

    2014-01-01

    Two graphic holistic metrics for assessing the greenness of synthesis, the "green star" and the "green circle", have been presented previously. These metrics assess the greenness by the degree of accomplishment of each of the 12 principles of green chemistry that apply to the case under evaluation. The criteria for assessment…

  18. Alternative energies. Updates on progress

    Energy Technology Data Exchange (ETDEWEB)

    Ferreira, German (ed.) [CIRCE - Centre of Research for Energy Resources and Consumption, Zaragoza (Spain)

    2013-07-01

    Presents fundamental and applied research of alternative energies. Address key pillars in the alternative energy field, such as: biomass energy, hydrogen energy, solar energy, wind energy, hydroelectric power, geothermal energy and their environmental implications, with the most updated progress. Includes the life cycle assessment and thermoeconomic analysis as tools for evaluating and optimising environmental and cost subjects. This book presents nine chapters based on fundamental and applied research of alternative energies. At the present time, the challenge is that technology has to come up with solutions that can provide environmentally friendly energy supply options that are able to cover the current world energy demand. Experts around the world are working on these issues for providing new solutions that will break the existing technological barriers. This book aims to address key pillars in the alternative energy field, such as: biomass energy, hydrogen energy, solar energy, wind energy, hydroelectric power, geothermal energy and their environmental implications, with the most updated progress for each pillar. It also includes the life cycle assessment (LCA) and thermoeconomic analysis (TA) as tools for evaluating and optimising environmental and cost subjects. Chapters are organized into fundamental research, applied research and future trends; and written for engineers, academic researches and scientists.

  19. Fisher: a program for the detection of H/ACA snoRNAs using MFE secondary structure prediction and comparative genomics – assessment and update

    Directory of Open Access Journals (Sweden)

    Tamas Ivica

    2008-07-01

    Full Text Available Abstract Background The H/ACA family of small nucleolar RNAs (snoRNAs plays a central role in guiding the pseudouridylation of ribosomal RNA (rRNA. In an effort to systematically identify the complete set of rRNA-modifying H/ACA snoRNAs from the genome sequence of the budding yeast, Saccharomyces cerevisiae, we developed a program – Fisher – and previously presented several candidate snoRNAs based on our analysis 1. Findings In this report, we provide a brief update of this work, which was aborted after the publication of experimentally-identified snoRNAs 2 identical to candidates we had identified bioinformatically using Fisher. Our motivation for revisiting this work is to report on the status of the candidate snoRNAs described in 1, and secondly, to report that a modified version of Fisher together with the available multiple yeast genome sequences was able to correctly identify several H/ACA snoRNAs for modification sites not identified by the snoGPS program 3. While we are no longer developing Fisher, we briefly consider the merits of the Fisher algorithm relative to snoGPS, which may be of use for workers considering pursuing a similar search strategy for the identification of small RNAs. The modified source code for Fisher is made available as supplementary material. Conclusion Our results confirm the validity of using minimum free energy (MFE secondary structure prediction to guide comparative genomic screening for RNA families with few sequence constraints.

  20. Update of European bioethics

    DEFF Research Database (Denmark)

    Rendtorff, Jacob Dahl

    2015-01-01

    This paper presents an update of the research on European bioethics undertaken by the author together with Professor Peter Kemp since the 1990s, on Basic ethical principles in European bioethics and biolaw. In this European approach to basic ethical principles in bioethics and biolaw, the princip......This paper presents an update of the research on European bioethics undertaken by the author together with Professor Peter Kemp since the 1990s, on Basic ethical principles in European bioethics and biolaw. In this European approach to basic ethical principles in bioethics and biolaw......, the principles of autonomy, dignity, integrity and vulnerability are proposed as the most important ethical principles for respect for the human person in biomedical and biotechnological development. This approach to bioethics and biolaw is presented here in a short updated version that integrates the earlier...

  1. Multiple Sclerosis: An Update.

    Science.gov (United States)

    Faguy, Kathryn

    2016-05-01

    Multiple sclerosis (MS) is the most common disabling neurologic condition in young adults and imposes high financial and quality of life costs on patients, their families, and society. Yet, developments in the battle against MS include new treatments to slow its progression and updated diagnostic criteria that can accelerate diagnosis and effective treatment. This article offers a review and update on the disease, focusing on risk factors and possible causes, symptoms, forms of MS, diagnostic criteria and tools, and the expanding array of approved treatments. It also reports on the skyrocketing cost of MS drugs, misdiagnosis, and special patient populations with MS.

  2. Guideline update for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 2: assessment of functional outcome following lumbar fusion.

    Science.gov (United States)

    Ghogawala, Zoher; Resnick, Daniel K; Watters, William C; Mummaneni, Praveen V; Dailey, Andrew T; Choudhri, Tanvir F; Eck, Jason C; Sharan, Alok; Groff, Michael W; Wang, Jeffrey C; Dhall, Sanjay S; Kaiser, Michael G

    2014-07-01

    Assessment of functional patient-reported outcome following lumbar spinal fusion continues to be essential for comparing the effectiveness of different treatments for patients presenting with degenerative disease of the lumbar spine. When assessing functional outcome in patients being treated with lumbar spinal fusion, a reliable, valid, and responsive outcomes instrument such as the Oswestry Disability Index should be used. The SF-36 and the SF-12 have emerged as dominant measures of general health-related quality of life. Research has established the minimum clinically important difference for major functional outcomes measures, and this should be considered when assessing clinical outcome. The results of recent studies suggest that a patient's pretreatment psychological state is a major independent variable that affects the ability to detect change in functional outcome.

  3. GFO and JASON Altimeter Engineering Assessment Report. Update: GFO--Acceptance to December 27, 2007, JASON--Acceptance to December 26, 2007. Version 1: June 2008

    Science.gov (United States)

    Conger, A. M.; Hancock, D. W.; Hayne, G. S.; Brooks, R. L.

    2008-01-01

    The purpose of this document is to present and document GEOSAT Follow-On (GFO) performance analyses and results. This is the eighth Assessment Report since the initial report. This report extends the performance assessment since acceptance to 27 December 2007. Since launch, a variety of GFO performance studies have been performed: Appendix A provides an accumulative index of those studies. We began the inclusion of analyses of the JASON altimeter after the end of the Topographic Experiment (TOPEX) mission. Prior to this, JASON and TOPEX were compared during our assessment of theTOPEX altimeter. With the end of the TOPEX mission, we developed methods to report on JASON as it relates to GFO.

  4. National assessment of shoreline change: A GIS compilation of updated vector shorelines and associated shoreline change data for the Southeast Atlantic coast

    Science.gov (United States)

    Kratzmann, Meredith; Himmelstoss, Emily; Thieler, E. Robert

    2017-01-01

    Sandy ocean beaches in the United States are popular tourist and recreational destinations and constitute some of the most valuable real estate in the country.The boundary between land and water along the coastline is often the location of concentrated residential and commercial development and is frequently exposed to a range of natural hazards, which include flooding, storm effects, and coastal erosion.  In response, the U.S. Geological Survey (USGS) is conducting a national assessment of coastal change hazards.  One component of this research effort, the National Assessment of Shoreline Change Project (http://coastal.er.usgs.gov/shoreline-change/), documents changes in shoreline position as a proxy for coastal change. Shoreline position is an easily understood feature representing the historical location of a beach position through time. All data can be viewed on the National Assessment of Coastal Change Hazards Portal at https://marine.usgs.gov/coastalchangehazardsportal/

  5. GFO and JASON Altimeter Engineering Assessment Report. Update: GFO-Acceptance to End of Mission on October 22, 2008, JASON-Acceptance to September 29, 2008

    Science.gov (United States)

    Conger, A. M.; Hancock, D. W., III; Hayne, G. S.; Brooks, R. L.

    2009-01-01

    The purpose of this document is to present and document GEOSAT Follow-On (GFO) performance analyses and results. This is the ninth Assessment Report since the initial report and is our final one. This report extends the performance assessment since acceptance on November 29, 2000 to the end of mission (EOM) on October 22, 2008. Since launch, February 10, 1998 to the EOM, we performed a variety of GFO performance studies; Appendix A provides an accumulative index of those studies. We began the inclusion of analyses of the JASON altimeter after the end of the Topographic Experiment (TOPEX) mission. Prior to this, JASON and TOPEX were compared during our assessment of the TOPEX altimeter. With the end of the TOPEX mission, we developed methods to report on JASON as it related to GFO. It should be noted the GFO altimeter, after operating for over 7 years, was power cycled off to on and on to off approximately 14 times a day for over 18 months in space with no failure. The GFO altimeter proved to be a remarkable instrument providing stable ocean surface measurements for nearly eight years. This report completes our GFO altimeter performance assessment.

  6. A temporal importance-performance analysis of recreation attributes on national forests: a technical document supporting the Forest Service update of the 2010 RPA Assessment

    Science.gov (United States)

    Ashley E. Askew; J.M. Bowker; Donald B.K. English; Stanley J. Zarnoch; Gary T. Green

    2017-01-01

    The outdoor recreation component of the 2010 Resources Planning Act (RPA) Assessment provided projections and modeling of participation and intensity by activity. Results provided insight into the future of multiple outdoor recreation activities through projections of participation rates, numbers of participants, days per participant, and total activity days. These...

  7. XLMR genes: update 2000.

    NARCIS (Netherlands)

    Chiurazzi, P.; Hamel, B.C.J.; Neri, G.

    2001-01-01

    This is the sixth edition of the catalogue of XLMR genes, ie X-linked genes whose malfunctioning causes mental retardation. The cloning era is not yet concluded, actually much remains to be done to account for the 202 XLMR conditions listed in this update. Many of these may eventually prove to be du

  8. Updating Older Fume Hoods.

    Science.gov (United States)

    Saunders, G. Thomas

    1985-01-01

    Provides information on updating older fume hoods. Areas addressed include: (1) adjustment of the hood's back baffle; (2) hood air leakage; (3) light level; (4) hood location in relation to room traffic and room air; and (5) establishing and maintaining hood performance. (JN)

  9. Update of telephone exchange

    CERN Multimedia

    2006-01-01

    As part of the upgrade of telephone services, the CERN switching centre will be updated on between Monday 23 October 8.00 p.m. and Tuesday 24 October 2.00 a.m. Telephone services may be disrupted and possibly even interrupted during this operation. We apologise in advance for any inconvenience this may cause. CERN TELECOM Service

  10. Update of telephone exchange

    CERN Multimedia

    2006-01-01

    As part of the upgrade of telephone services, the CERN switching centre will be updated on Monday 3 July between 8.00 p.m. and 3.00 a.m. Telephone services may be disrupted and possibly even interrupted during this operation. We apologise in advance for any inconvenience this may cause. CERN TELECOM Service

  11. Update of telephone exchange

    CERN Multimedia

    2006-01-01

    As part of the upgrade of telephone services, the CERN switching centre will be updated on Wednesday 14 June between 8.00 p.m. and midnight. Telephone services may be disrupted and possibly even interrupted during this operation. We apologise in advance for any inconvenience this may cause. CERN TELECOM Service

  12. Update of telephone exchange

    CERN Multimedia

    2006-01-01

    As part of the upgrade of telephone services, the CERN switching centre will be updated on Monday 3 July between 8.00 p.m. and 3.00 a.m. Telephone services may be disrupted and possibly even interrupted during this operation.We apologise in advance for any inconvenience this may cause. CERN TELECOM Service

  13. Sugammadex: An Update

    Directory of Open Access Journals (Sweden)

    Ezri Tiberiu

    2016-01-01

    Full Text Available The purpose of this update is to provide recent knowledge and debates regarding the use of sugammadex in the fields of anesthesia and critical care. The review is not intended to provide a comprehensive description of sugammadex and its clinical use.

  14. Valence-Dependent Belief Updating: Computational Validation.

    Science.gov (United States)

    Kuzmanovic, Bojana; Rigoux, Lionel

    2017-01-01

    People tend to update beliefs about their future outcomes in a valence-dependent way: they are likely to incorporate good news and to neglect bad news. However, belief formation is a complex process which depends not only on motivational factors such as the desire for favorable conclusions, but also on multiple cognitive variables such as prior beliefs, knowledge about personal vulnerabilities and resources, and the size of the probabilities and estimation errors. Thus, we applied computational modeling in order to test for valence-induced biases in updating while formally controlling for relevant cognitive factors. We compared biased and unbiased Bayesian models of belief updating, and specified alternative models based on reinforcement learning. The experiment consisted of 80 trials with 80 different adverse future life events. In each trial, participants estimated the base rate of one of these events and estimated their own risk of experiencing the event before and after being confronted with the actual base rate. Belief updates corresponded to the difference between the two self-risk estimates. Valence-dependent updating was assessed by comparing trials with good news (better-than-expected base rates) with trials with bad news (worse-than-expected base rates). After receiving bad relative to good news, participants' updates were smaller and deviated more strongly from rational Bayesian predictions, indicating a valence-induced bias. Model comparison revealed that the biased (i.e., optimistic) Bayesian model of belief updating better accounted for data than the unbiased (i.e., rational) Bayesian model, confirming that the valence of the new information influenced the amount of updating. Moreover, alternative computational modeling based on reinforcement learning demonstrated higher learning rates for good than for bad news, as well as a moderating role of personal knowledge. Finally, in this specific experimental context, the approach based on reinforcement

  15. Valence-Dependent Belief Updating: Computational Validation

    Directory of Open Access Journals (Sweden)

    Bojana Kuzmanovic

    2017-06-01

    Full Text Available People tend to update beliefs about their future outcomes in a valence-dependent way: they are likely to incorporate good news and to neglect bad news. However, belief formation is a complex process which depends not only on motivational factors such as the desire for favorable conclusions, but also on multiple cognitive variables such as prior beliefs, knowledge about personal vulnerabilities and resources, and the size of the probabilities and estimation errors. Thus, we applied computational modeling in order to test for valence-induced biases in updating while formally controlling for relevant cognitive factors. We compared biased and unbiased Bayesian models of belief updating, and specified alternative models based on reinforcement learning. The experiment consisted of 80 trials with 80 different adverse future life events. In each trial, participants estimated the base rate of one of these events and estimated their own risk of experiencing the event before and after being confronted with the actual base rate. Belief updates corresponded to the difference between the two self-risk estimates. Valence-dependent updating was assessed by comparing trials with good news (better-than-expected base rates with trials with bad news (worse-than-expected base rates. After receiving bad relative to good news, participants' updates were smaller and deviated more strongly from rational Bayesian predictions, indicating a valence-induced bias. Model comparison revealed that the biased (i.e., optimistic Bayesian model of belief updating better accounted for data than the unbiased (i.e., rational Bayesian model, confirming that the valence of the new information influenced the amount of updating. Moreover, alternative computational modeling based on reinforcement learning demonstrated higher learning rates for good than for bad news, as well as a moderating role of personal knowledge. Finally, in this specific experimental context, the approach based on

  16. Enhanced and updated spatially referenced statistical assessment of dissolved-solids load sources and transport in streams of the Upper Colorado River Basin

    Science.gov (United States)

    Miller, Matthew P.; Buto, Susan G.; Lambert, Patrick M.; Rumsey, Christine A.

    2017-03-07

    Approximately 6.4 million tons of dissolved solids are discharged from the Upper Colorado River Basin (UCRB) to the Lower Colorado River Basin each year. This results in substantial economic damages, and tens of millions of dollars are spent annually on salinity control projects designed to reduce salinity loads in surface waters of the UCRB. Dissolved solids in surface water and groundwater have been studied extensively over the past century, and these studies have contributed to a conceptual understanding of sources and transport of dissolved solids. This conceptual understanding was incorporated into a Spatially Referenced Regressions on Watershed Attributes (SPARROW) model to examine sources and transport of dissolved solids in the UCRB. The results of this model were published in 2009. The present report documents the methods and data used to develop an updated dissolved-solids SPARROW model for the UCRB, and incorporates data defining current basin attributes not available in the previous model, including delineation of irrigated lands by irrigation type (sprinkler or flood irrigation), and calibration data from additional monitoring sites.Dissolved-solids loads estimated for 312 monitoring sites were used to calibrate the SPARROW model, which predicted loads for each of 10,789 stream reaches in the UCRB. The calibrated model provided a good fit to the calibration data as evidenced by R2 and yield R2 values of 0.96 and 0.73, respectively, and a root-mean-square error of 0.47. The model included seven geologic sources that have estimated dissolved-solids yields ranging from approximately 1 to 45 tons per square mile (tons/mi2). Yields generated from irrigated agricultural lands are substantially greater than those from geologic sources, with sprinkler irrigated lands generating an average of approximately 150 tons/mi2 and flood irrigated lands generating between 770 and 2,300 tons/mi2 depending on underlying lithology. The coefficients estimated for six

  17. The Impact of Medical Student Participation in Emergency Medicine Patient Care on Departmental Press Ganey Scores

    Directory of Open Access Journals (Sweden)

    Aaron W. Bernard

    2015-10-01

    Full Text Available Introduction: Press Ganey (PG scores are used by public entities to gauge the quality of patient care from medical facilities in the United States. Academic health centers (AHCs are charged with educating the new generation of doctors, but rely heavily on PG scores for their business operation. AHCs need to know what impact medical student involvement has on patient care and their PG scores. Purpose: We sought to identify the impact students have on emergency department (ED PG scores related to overall visit and the treating physician’s performance. Methods: This was a retrospective, observational cohort study of discharged ED patients who completed PG satisfaction surveys at one academic, and one community-based ED. Outcomes were responses to questions about the overall visit assessment and doctor’s care, measured on a five-point scale. We compared the distribution of responses for each question through proportions with 95% confidence intervals (CIs stratified by medical student participation. For each question, we constructed a multivariable ordinal logistic regression model including medical student involvement and other independent variables known to affect PG scores. Results: We analyzed 2,753 encounters, of which 259 (9.4% had medical student involvement. For all questions, there were no appreciable differences in patient responses when stratifying by medical student involvement. In regression models, medical student involvement was not associated with PG score for any outcome, including overall rating of care (odds ratio [OR] 1.10, 95% CI [0.90-1.34] or likelihood of recommending our EDs (OR 1.07, 95% CI [0.86-1.32]. Findings were similar when each ED was analyzed individually. Conclusion: We found that medical student involvement in patient care did not adversely impact ED PG scores in discharged patients. Neither overall scores nor physician-specific scores were impacted. Results were similar at both the academic medical center and

  18. The Impact of Medical Student Participation in Emergency Medicine Patient Care on Departmental Press Ganey Scores

    Science.gov (United States)

    Bernard, Aaron W.; Martin, Daniel R.; Moseley, Mark G.; Kman, Nicholas E.; Khandelwal, Sorabh; Carpenter, Daniel; Way, David P.; Caterino, Jeffrey M.

    2015-01-01

    Introduction Press Ganey (PG) scores are used by public entities to gauge the quality of patient care from medical facilities in the United States. Academic health centers (AHCs) are charged with educating the new generation of doctors, but rely heavily on PG scores for their business operation. AHCs need to know what impact medical student involvement has on patient care and their PG scores. Purpose We sought to identify the impact students have on emergency department (ED) PG scores related to overall visit and the treating physician’s performance. Methods This was a retrospective, observational cohort study of discharged ED patients who completed PG satisfaction surveys at one academic, and one community-based ED. Outcomes were responses to questions about the overall visit assessment and doctor’s care, measured on a five-point scale. We compared the distribution of responses for each question through proportions with 95% confidence intervals (CIs) stratified by medical student participation. For each question, we constructed a multivariable ordinal logistic regression model including medical student involvement and other independent variables known to affect PG scores. Results We analyzed 2,753 encounters, of which 259 (9.4%) had medical student involvement. For all questions, there were no appreciable differences in patient responses when stratifying by medical student involvement. In regression models, medical student involvement was not associated with PG score for any outcome, including overall rating of care (odds ratio [OR] 1.10, 95% CI [0.90–1.34]) or likelihood of recommending our EDs (OR 1.07, 95% CI [0.86–1.32]). Findings were similar when each ED was analyzed individually. Conclusion We found that medical student involvement in patient care did not adversely impact ED PG scores in discharged patients. Neither overall scores nor physician-specific scores were impacted. Results were similar at both the academic medical center and the community

  19. Prevalence of Polycystic Ovary Syndrome Phenotypes Using Updated Criteria for Polycystic Ovarian Morphology: An Assessment of Over 100 Consecutive Women Self-reporting Features of Polycystic Ovary Syndrome

    OpenAIRE

    Clark, Nina M.; Podolski, Amanda J.; Brooks, Eric D; Chizen, Donna R.; Pierson, Roger A.; Lehotay, Denis C; Lujan, Marla E.

    2014-01-01

    The prevalence of polycystic ovary syndrome (PCOS) and its distinct clinical phenotypes were assessed using 3 sets of international diagnostic criteria in women self-reporting concerns over outward features of PCOS. Revised ultrasonographic criteria for polycystic ovaries (PCO) based on modern ultrasound technology were used. Of the participants, 53%, 62%, and 70% were diagnosed with PCOS using National Institutes of Health, Androgen Excess and PCOS Society, and Rotterdam criteria, respective...

  20. Endocrine disrupting chemicals and other substances of concern in food contact materials: an updated review of exposure, effect and risk assessment.

    Science.gov (United States)

    Muncke, Jane

    2011-10-01

    Food contact materials (FCM) are an underestimated source of chemical food contaminants and a potentially relevant route of human exposure to endocrine disrupting chemicals (EDCs). Quantifying the exposure of the general population to substances from FCM relies on estimates of food consumption and leaching into food. Recent studies using polycarbonate plastics show that food simulants do not always predict worst-case leaching of bisphenol A, a common FCM substance. Also, exposure of children to FCM substances is not always realistically predicted using the common conventions and thus possibly misjudged. Further, the exposure of the whole population to substances leaching into dry foods is underestimated. Consumers are exposed to low levels of substances from FCM across their entire lives. Effects of these compounds currently are assessed with a focus on mutagenicity and genotoxicity. This approach however neglects integrating recent new toxicological findings, like endocrine disruption, mixture toxicity, and developmental toxicity. According to these new toxicology paradigms women of childbearing age and during pregnancy are a new sensitive population group requiring more attention. Furthermore, in overweight and obese persons a change in the metabolism of xenobiotics is observed, possibly implying that this group of consumers is insufficiently protected by current risk assessment practice. Innovations in FCM risk assessment should therefore include routine testing for EDCs and an assessment of the whole migrate toxicity of a food packaging, taking into account all sensitive population groups. In this article I focus on recent issues of interest concerning either exposure to or effects of FCM-related substances. Further, I review the use of benzophenones and organotins, two groups of known or suspected EDCs, in FCM authorized in the US and EU.

  1. Results of the global conservation assessment of the freshwater crabs (Brachyura, Pseudothelphusidae and Trichodactylidae): The Neotropical region, with an update on diversity

    Science.gov (United States)

    Cumberlidge, Neil; Alvarez, Fernando; Villalobos, Jose-Luis

    2014-01-01

    Abstract The freshwater crabs of the Neotropics comprise 311 species in two families (Pseudothelphusidae and Trichodactylidae) and one or both of these families are found in all of the countries in the Neotropical region (except for Chile and some of the Caribbean islands). Colombia (102 species, 81% endemic) and Mexico (67 species, 95% endemic) are the biodiversity hotspots of freshwater crab species richness and country-level endemism for this region. The results of the IUCN Red List conservation assessments show that 34% of pseudothelphusids and 10% of trichodactylids have an elevated risk of extinction, 29% of pseudothelphusids and 75% of trichodactylids are not at-risk (Least Concern), and although none are actually extinct, 56% of pseudothelphusids and 17% of trichodactylids are too poorly known to assess (Data Deficient). Colombia (14 species), Venezuela (7 species), Mexico (6 species), and Ecuador (5 species) are the countries with the highest number of threatened species of Neotropical freshwater crabs. The majority of threatened species are restricted-range semiterrestrial endemics living in habitats subjected to deforestation, alteration of drainage patterns, and pollution. This underlines the need to prioritize and develop conservation measures before species decline to levels from which they cannot recover. These results represent a baseline that can be used to design strategies to save threatened Neotropical species of freshwater crabs. PMID:25561834

  2. Results of the global conservation assessment of the freshwater crabs (Brachyura, Pseudothelphusidae and Trichodactylidae: The Neotropical region, with an update on diversity

    Directory of Open Access Journals (Sweden)

    Neil Cumberlidge

    2014-11-01

    Full Text Available The freshwater crabs of the Neotropics comprise 311 species in two families (Pseudothelphusidae and Trichodactylidae and one or both of these families are found in all of the countries in the Neotropical region (except for Chile and some of the Caribbean islands. Colombia (102 species, 81% endemic and Mexico (67 species, 95% endemic are the biodiversity hotspots of freshwater crab species richness and country-level endemism for this region. The results of the IUCN Red List conservation assessments show that 34% of pseudothelphusids and 10% of trichodactylids have an elevated risk of extinction, 29% of pseudothelphusids and 75% of trichodactylids are not at-risk (Least Concern, and although none are actually extinct, 56% of pseudothelphusids and 17% of trichodactylids are too poorly known to assess (Data Deficient. Colombia (14 species, Venezuela (7 species, Mexico (6 species, and Ecuador (5 species are the countries with the highest number of threatened species of Neotropical freshwater crabs. The majority of threatened species are restricted-range semiterrestrial endemics living in habitats subjected to deforestation, alteration of drainage patterns, and pollution. This underlines the need to prioritize and develop conservation measures before species decline to levels from which they cannot recover. These results represent a baseline that can be used to design strategies to save threatened Neotropical species of freshwater crabs.

  3. Results of the global conservation assessment of the freshwater crabs (Brachyura, Pseudothelphusidae and Trichodactylidae): The Neotropical region, with an update on diversity.

    Science.gov (United States)

    Cumberlidge, Neil; Alvarez, Fernando; Villalobos, Jose-Luis

    2014-01-01

    The freshwater crabs of the Neotropics comprise 311 species in two families (Pseudothelphusidae and Trichodactylidae) and one or both of these families are found in all of the countries in the Neotropical region (except for Chile and some of the Caribbean islands). Colombia (102 species, 81% endemic) and Mexico (67 species, 95% endemic) are the biodiversity hotspots of freshwater crab species richness and country-level endemism for this region. The results of the IUCN Red List conservation assessments show that 34% of pseudothelphusids and 10% of trichodactylids have an elevated risk of extinction, 29% of pseudothelphusids and 75% of trichodactylids are not at-risk (Least Concern), and although none are actually extinct, 56% of pseudothelphusids and 17% of trichodactylids are too poorly known to assess (Data Deficient). Colombia (14 species), Venezuela (7 species), Mexico (6 species), and Ecuador (5 species) are the countries with the highest number of threatened species of Neotropical freshwater crabs. The majority of threatened species are restricted-range semiterrestrial endemics living in habitats subjected to deforestation, alteration of drainage patterns, and pollution. This underlines the need to prioritize and develop conservation measures before species decline to levels from which they cannot recover. These results represent a baseline that can be used to design strategies to save threatened Neotropical species of freshwater crabs.

  4. NXE pellicle: development update

    Science.gov (United States)

    Brouns, Derk; Bendiksen, Aage; Broman, Par; Casimiri, Eric; Colsters, Paul; de Graaf, Dennis; Harrold, Hilary; Hennus, Piet; Janssen, Paul; Kramer, Ronald; Kruizinga, Matthias; Kuntzel, Henk; Lafarre, Raymond; Mancuso, Andrea; Ockwell, David; Smith, Daniel; van de Weg, David; Wiley, Jim

    2016-09-01

    ASML introduced the NXE pellicle concept, a removable pellicle solution that is compatible with current and future patterned mask inspection methods. We will present results of how we have taken the idea from concept to a demonstrated solution enabling the use of EUV pellicle by the industry for high volume manufacturing. We will update on the development of the next generation of pellicle films with higher power capability. Further, we will provide an update on top level requirements for pellicles and external interface requirements needed to support NXE pellicle adoption at a mask shop. Finally, we will present ASML's pellicle handling equipment to enable pellicle use at mask shops and our NXE pellicle roadmap outlining future improvements.

  5. Update on a Pharmacokinetic-Centric Alternative Tier II Program for MMT—Part II: Physiologically Based Pharmacokinetic Modeling and Manganese Risk Assessment

    Directory of Open Access Journals (Sweden)

    Michael D. Taylor

    2012-01-01

    Full Text Available Recently, a variety of physiologically based pharmacokinetic (PBPK models have been developed for the essential element manganese. This paper reviews the development of PBPK models (e.g., adult, pregnant, lactating, and neonatal rats, nonhuman primates, and adult, pregnant, lactating, and neonatal humans and relevant risk assessment applications. Each PBPK model incorporates critical features including dose-dependent saturable tissue capacities and asymmetrical diffusional flux of manganese into brain and other tissues. Varied influx and efflux diffusion rate and binding constants for different brain regions account for the differential increases in regional brain manganese concentrations observed experimentally. We also present novel PBPK simulations to predict manganese tissue concentrations in fetal, neonatal, pregnant, or aged individuals, as well as individuals with liver disease or chronic manganese inhalation. The results of these simulations could help guide risk assessors in the application of uncertainty factors as they establish exposure guidelines for the general public or workers.

  6. An update discussion on the current assessment of the safety of veterinary antimicrobial drug residues in food with regard to their impact on the human intestinal microbiome.

    Science.gov (United States)

    Cerniglia, Carl E; Pineiro, Silvia A; Kotarski, Susan F

    2016-05-01

    The human gastrointestinal tract ecosystem consists of complex and diverse microbial communities that have now been collectively termed the intestinal microbiome. Recent scientific breakthroughs and research endeavours have increased our understanding of the important role the intestinal microbiome plays in human health and disease. The use of antimicrobial new animal drugs in food-producing animals may result in the presence of low levels of drug residues in edible foodstuffs. There is concern that antimicrobial new animal drugs in or on animal-derived food products at residue-level concentrations could disrupt the colonization barrier and/or modify the antimicrobial resistance profile of human intestinal bacteria. Therapeutic doses of antimicrobial drugs have been shown to promote shifts in the intestinal microbiome, and these disruptions promote the emergence of antimicrobial-resistant bacteria. To assess the effects of antimicrobial new animal drug residues in food on human intestinal bacteria, many national regulatory agencies and international committees follow a harmonized process, VICH GL36(R), which was issued by a trilateral organization of the European Union, the USA, and Japan called the International Cooperation on Harmonization of Technical Requirements for Veterinary Medicinal Products (VICH). The guidance describes a general approach currently used by national regulatory agencies and international committees to assess the effects of antimicrobial new animal drug residues in animal-derived food on human intestinal bacteria. The purpose of this review is to provide an overview of this current approach as part of the antimicrobial new animal drug approval process in participating countries, give insights on the microbiological endpoints used in this safety evaluation, and discuss the availability of new information. Copyright © 2016 John Wiley & Sons, Ltd.

  7. Recycling, Canadian update

    Energy Technology Data Exchange (ETDEWEB)

    Lakshmanan, V. I. [Process Research ORTECH Inc., Mississauga, ON (Canada); Shaw, L. [Canadian Association of Recycling Industries, Almonte, ON (Canada)

    2001-07-01

    An update on the recycling industry in Canada is provided by way of selected examples involving the recovery of gallium from electronic scrap, magnesium recovery from mine tailings and energy recovery from metal industry processes. These examples have been selected to illustrate the synergy between major mining, metallurgical and utility industries with end users in the building materials, automotive and electronic industries. 1 tab., 1 fig.

  8. Ukraine Poverty Update

    OpenAIRE

    2007-01-01

    Ukraine recorded one of the sharpest declines in poverty of any transition economy in recent years. The poverty rate, measured against an absolute poverty line, fell from a high of 32 percent in 2001 to 14 percent in 2004, and then again to 8 percent in 2005. This Update presents simulations of the direct influence of an increase in energy prices on the poverty rate. Using 2005 as a base p...

  9. How Documentalists Update SIMBAD

    Science.gov (United States)

    Buga, M.; Bot, C.; Brouty, M.; Bruneau, C.; Brunet, C.; Cambresy, L.; Eisele, A.; Genova, F.; Lesteven, S.; Loup, C.; Neuville, M.; Oberto, A.; Ochsenbein, F.; Perret, E.; Siebert, A.; Son, E.; Vannier, P.; Vollmer, B.; Vonflie, P.; Wenger, M.; Woelfel, F.

    2015-04-01

    The Strasbourg astronomical Data Center (CDS) was created in 1972 and has had a major role in astronomy for more than forty years. CDS develops a service called SIMBAD that provides basic data, cross-identifications, bibliography, and measurements for astronomical objects outside the solar system. It brings to the scientific community an added value to content which is updated daily by a team of documentalists working together in close collaboration with astronomers and IT specialists. We explain how the CDS staff updates SIMBAD with object citations in the main astronomical journals, as well as with astronomical data and measurements. We also explain how the identification is made between the objects found in the literature and those already existing in SIMBAD. We show the steps followed by the documentalist team to update the database using different tools developed at CDS, like the sky visualizer Aladin, and the large catalogues and survey database VizieR. As a direct result of this teamwork, SIMBAD integrates almost 10.000 bibliographic references per year. The service receives more than 400.000 queries per day.

  10. Where are we going? An update on assessment, treatment, and neurobiological research in dissociative disorders as we move toward the DSM-5.

    Science.gov (United States)

    Brand, Bethany L; Lanius, Ruth; Vermetten, Eric; Loewenstein, Richard J; Spiegel, David

    2012-01-01

    This article provides an overview of the process of developing the 5th edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) of the American Psychiatric Association with a focus on issues related to the trauma-related disorders, particularly the dissociative disorders (DD). We also discuss the highlights of research within the past 5 years in the assessment, treatment, and neurobiological basis of trauma disorders. Recent research shows that DD are associated with severe symptoms as well as a higher rate of utilization of mental health treatment compared with other psychiatric disorders. As a result, DD, like other complex posttraumatic disorders, exact a high economic as well as personal burden for patients and society. The latest research indicates that DD patients show a suboptimal response to standard exposure-based treatments for posttraumatic stress disorder as well as high levels of attrition from treatment. An emerging body of research on DD treatment, primarily of naturalistic and open trials, indicates that patients who receive specialized treatment that addresses their trauma-based, dissociative symptoms show improved functioning and reduced symptoms. Recent studies of the underlying neurobiological basis for dissociation support a model of excessive limbic inhibition in DD that is consistent with the phenomenology and clinical presentation of these patients. We are optimistic that the forthcoming DSM-5 will stimulate research on dissociation and the DD and suggest areas for future studies.

  11. Relapse of departmental monopoly

    Energy Technology Data Exchange (ETDEWEB)

    Abramson, Kh.I.

    1990-06-01

    Argues that although it may have once been sensible for coal mining machine building to be subordinate to the USSR Ministry of the Coal Industry this is no longer the case. Although there are some types of machines that are used only by the coal industry, most have applications in other areas, but the Ministry of the Coal Industry does not show enough interest in areas outside its own field. One of many examples cited is that subway construction companies have found it virtually impossible to obtain the 1GPKS cutter loader. The result of this kind of attitude is that many ministries and authorities are finding it necessary to duplicate the development and production of tunneling and similar equipment, often with unsatisfactory results. Suggests that development and production of this kind of equipment be taken over by those companies that are no longer required by the defense industry and also suggests cooperation with foreign mining machine building companies.

  12. Update to Assessment of Direct Disposal in Unsaturated Tuff of Spent Nuclear Fuel and High-Level Waste Owned by U.S. Department of Energy

    Energy Technology Data Exchange (ETDEWEB)

    P. D. Wheatley (INEEL POC); R. P. Rechard (SNL)

    1998-09-01

    The overall purpose of this study is to provide information and guidance to the Office of Environmental Management of the U.S. Department of Energy (DOE) about the level of characterization necessary to dispose of DOE-owned spent nuclear fuel (SNF). The disposal option modeled was codisposal of DOE SNF with defense high-level waste (DHLW). A specific goal was to demonstrate the influence of DOE SNF, expected to be minor, in a predominately commercial repository using modeling conditions similar to those currently assumed by the Yucca Mountain Project (YMP). A performance assessment (PA) was chosen as the method of analysis. The performance metric for this analysis (referred to as the 1997 PA) was dose to an individual; the time period of interest was 100,000 yr. Results indicated that cumulative releases of 99Tc and 237Np (primary contributors to human dose) from commercial SNF exceed those of DOE SNF both on a per MTHM and per package basis. Thus, if commercial SNF can meet regulatory performance criteria for dose to an individual, then the DOE SNF can also meet the criteria. This result is due in large part to lower burnup of the DOE SNF (less time for irradiation) and to the DOE SNF's small percentage of the total activity (1.5%) and mass (3.8%) of waste in the potential repository. Consistent with the analyses performed for the YMP, the 1997 PA assumed all cladding as failed, which also contributed to the relatively poor performance of commercial SNF compared to DOE SNF.

  13. Relevance of the 1-year dog study in assessing human health risks for registration of pesticides. An update to include pesticides registered in Japan.

    Science.gov (United States)

    Kobel, Werner; Fegert, Ivana; Billington, Richard; Lewis, Richard; Bentley, Karin; Langrand-Lerche, Carole; Botham, Phil; Sato, Masako; Debruyne, Eric; Strupp, Christian; van Ravenzwaay, Bennard

    2014-11-01

    Over 400 active pesticides are registered in Japan (FAMIC 2013). The results of dog toxicity studies (usually, the 1-year study) were used by the Japanese regulatory authorities to establish the acceptable daily intake (ADI) for 45 pesticide active ingredients (about 9%). A retrospective review of ADIs established in Japan with dog studies as pivotal data for their derivation was performed: the ADIs were reassessed under the assumption that the 1-year dog study would not be available and an alternate ADI was derived based on the remaining toxicology database. In 35 of the 45 cases (77.8%) the ADI resulting from the absence of the 1-year dog study was no greater than twice the Japanese ADI, a difference considered not to be of biological significance. In 6 cases (13%) the resulting ADI was 2-5 times higher, which is considered of questionable biological relevance. On further evaluation of the database, three of these six cases were assessed as to clarify that there is no clear difference and for the other three additional studies to clarify that uncertain findings would have been required. In 3 of the 45 cases (7%) there may be a real difference within the ADI ratio of 2-5. Only in 1 case (2.2%) ADI was five times higher than that has been set. Accordingly, the absence of a 1-year dog study does not appear to influence the ADI derivation in a relevant manner in more than 98% of cases. For the four compounds with a real difference in ADI, consumer exposure would still be well below the alternative ADI. Therefore, a strong case can be made that the standard mandatory requirement to conduct a 1-year dog study, in addition to the 3-month study, is not justified and of no additional value in protecting human health. In addition, a substantial reduction in test animals could be achieved.

  14. Guidance for updating clinical practice guidelines: a systematic review of methodological handbooks.

    Science.gov (United States)

    Vernooij, Robin W M; Sanabria, Andrea Juliana; Solà, Ivan; Alonso-Coello, Pablo; Martínez García, Laura

    2014-01-02

    Updating clinical practice guidelines (CPGs) is a crucial process for maintaining the validity of recommendations. Methodological handbooks should provide guidance on both developing and updating CPGs. However, little is known about the updating guidance provided by these handbooks. We conducted a systematic review to identify and describe the updating guidance provided by CPG methodological handbooks and included handbooks that provide updating guidance for CPGs. We searched in the Guidelines International Network library, US National Guidelines Clearinghouse and MEDLINE (PubMed) from 1966 to September 2013. Two authors independently selected the handbooks and extracted the data. We used descriptive statistics to analyze the extracted data and conducted a narrative synthesis. We included 35 handbooks. Most handbooks (97.1%) focus mainly on developing CPGs, including variable degrees of information about updating. Guidance on identifying new evidence and the methodology of assessing the need for an update is described in 11 (31.4%) and eight handbooks (22.8%), respectively. The period of time between two updates is described in 25 handbooks (71.4%), two to three years being the most frequent (40.0%). The majority of handbooks do not provide guidance for the literature search, evidence selection, assessment, synthesis, and external review of the updating process. Guidance for updating CPGs is poorly described in methodological handbooks. This guidance should be more rigorous and explicit. This could lead to a more optimal updating process, and, ultimately to valid trustworthy guidelines.

  15. Cohort Profile Update

    DEFF Research Database (Denmark)

    Omland, Lars Haukali; Ahlström, Magnus Glindvad; Obel, Niels

    2014-01-01

    The DHCS is a cohort of all HIV-infected individuals seen in one of the eight Danish HIV centres after 31 December 1994. Here we update the 2009 cohort profile emphasizing the development of the cohort. Every 12-24 months, DHCS is linked with the Danish Civil Registration System (CRS) in order...... of Causes of Death, the Danish National Prescription Registry, the Attainment Register and the Integrated Database for Labour Market Research to get information on vital status, migration, cancer, hospital contacts, causes of death, dispensed prescriptions, education and employment. Using this design, rates...

  16. Context updates are hierarchical

    Directory of Open Access Journals (Sweden)

    Anton Karl Ingason

    2016-10-01

    Full Text Available This squib studies the order in which elements are added to the shared context of interlocutors in a conversation. It focuses on context updates within one hierarchical structure and argues that structurally higher elements are entered into the context before lower elements, even if the structurally higher elements are pronounced after the lower elements. The crucial data are drawn from a comparison of relative clauses in two head-initial languages, English and Icelandic, and two head-final languages, Korean and Japanese. The findings have consequences for any theory of a dynamic semantics.

  17. Updates in pediatric endocrinology.

    Science.gov (United States)

    Kamboj, Manmohan K

    2013-04-01

    There are rapid advances being made in the field of medicine! New research continues to investigate etiopathogenic mechanisms underlying many endocrine disorders, new tests to facilitate diagnosis, and newer treatment options. The discussion in this article focuses on a few of the important concerns in adolescent endocrinology and highlights some recent concepts that are important for the physicians taking care of these adolescents. This article also includes a brief update on diabetes mellitus types 1 and 2, obesity, and polycystic ovarian syndrome; new thoughts and controversies about vitamin D and current management of the common thyroid disorders; adrenal insufficiency; and concerns with disorders of puberty in adolescents.

  18. Lodging Update: Greater Boston

    Directory of Open Access Journals (Sweden)

    Rachel Roginsky

    2012-09-01

    Full Text Available Pinnacle Advisory Group provides an update of lodging industry performance in New England and Boston for the first half of 2012. While the New England region outpaced the nation, the specific story varies from state to state. Only Massachusetts and Vermont achieved REVPAR performance better than the national average. A review of the Greater Boston lodging market reveals that a healthy local economy and strong convention calendar, combined with a number of one-time events and limited new supply, boosted the local market in 2012. The outlook for 2013 in Greater Boston remains positive, with expectations of a 4.7% growth in REVPAR.

  19. CONSULTATION ON UPDATED METHODOLOGY FOR ...

    Science.gov (United States)

    The National Academy of Sciences (NAS) expects to publish the Biological Effects of Ionizing Radiation (BEIR) committee's report (BEIR VII) on risks from ionizing radiation exposures in calendar year 2005. The committee is expected to have analyzed the most recent epidemiology from the important exposed cohorts and to have factored in any changes resulting from the updated analysis of dosimetry for the Japanese atomic bomb survivors. To the extent practical, the Committee will also consider any relevant radiobiological data, including those from the Department of Energy's low dose effects research program. Based on their evaluation of relevant information, the Committee is then expected to propose a set of models for estimating risks from low-dose ionizing radiation. ORIA will review the BEIR VII report and consider revisions to the Agency's methodology for estimating cancer risks from exposure to ionizing radiation in light of this report and other relevant information. This will be the subject of the Consultation. This project supports a major risk management initiative to improve the basis on which radiation risk decisions are made. This project, funded by several Federal Agencies, reflects an attempt to characterize risks where there are substantial uncertainties. The outcome will improve our ability to assess risks well into the future and will strengthen EPAs overall capability for assessing and managing radiation risks. the BEIR VII report is funde

  20. Craniosynostosis update 1987.

    Science.gov (United States)

    Cohen, M M

    1988-01-01

    Information on craniosynostosis in this paper updates "Craniosynostosis: Diagnosis, Evaluation, and Management" (Cohen MM Jr: New York: Raven Press, 1986). It also discusses recent developments that were included in the book but need further explanation or emphasis. Subjects discussed are: epidemiology, etiology, sutural biology, growth and development, neurological and psychosocial aspects, surgery, cloverleaf skulls, craniosynostosis syndromes, and prenatal diagnosis. Under the subject of etiology, fetal head constraint, maternal thyroid disease, calcified cephalohematoma, teratogens, and delayed suture closure and Wormian bones are considered. An updating of 15 cloverleaf skull conditions includes four monogenic disorders, two chromosomal disorders, one disruption, one iatrogenic condition, and seven syndromes of unknown cause. Newly recognized disorders with cloverleaf skull include Beare-Stevenson cutis gyratum syndrome and Say-Poznanski syndrome. Craniosynostosis syndromes and associations discussed include acrocraniofacial dysostosis, Apert syndrome, Beare-Stevenson cutis gyratum syndrome, Calabro syndrome, calvarial hyperostosis, chromosomal craniostenosis, Cole-Carpenter type osteogenesis imperfecta, Crouzon syndrome, Curry-Jones syndrome, Curry variant of Carpenter syndrome, cutis aplasia and cranial stenosis, Fontaine-Farriaux syndrome, Gomex-López-Hernández syndrome, Hersh syndrome, hyper-IgE syndrome and craniostenosis, hypomandibular faciocranial dysostosis, Marfanoid features and craniostenosis, Pfeiffer-type cardiocranial syndrome, Pfeiffer-type dolichocephalosyndactyly, and Say-Barber syndrome.

  1. Titan's gravity: An update

    Science.gov (United States)

    Durante, D.; Iess, L.; Racioppa, P.; Armstrong, J. W.; Lunine, J. I.; Stevenson, D. J.; Tortora, P.

    2016-12-01

    Since its arrival at Saturn in 2004, Cassini performed nine flybys devoted to the determination of Titan's gravity field and its tidal variations. The last gravity flyby of the mission (T122) took place on Aug. 10, 2016. We will present an updated gravity solution, based on all available data. These include also an additional flyby (T110, March 2015, primarily devoted to the imaging Titan's north polar lakes) carried out with the low gain antenna. This flyby was particularly valuable because closest approach occurred at high latitude (75°N), over an area not previously sampled. Published gravity results (Iess et al., 2012) indicated that Titan is subject to large eccentricity tides in response to Saturn's time varying forcing field. The magnitude of the response quadrupole field, controlled by the Love number k2, was used to infer the existence of an internal ocean. The new gravity field determination provides a better estimate of k2, to a level of a few percent. In addition to a full 3x3 field, the new solution includes also higher degree and order harmonic coefficients (such as J4) and offers an improved map of gravity anomalies. The updated geoid and its associated uncertainty could be used to refine the gravity-altimetry correlative analysis and for improved interpretation of radar altimetric data.

  2. Updated U.S. Geothermal Supply Characterization

    Energy Technology Data Exchange (ETDEWEB)

    Petty, S.; Porro, G.

    2007-03-01

    This paper documents the approach taken to characterize and represent an updated assessment of U.S. geothermal supply for use in forecasting the penetration of geothermal electrical generation in the National Energy Modeling System (NEMS). This work is motivated by several factors: The supply characterization used as the basis of several recent U.S. Department of Energy (DOE) forecasts of geothermal capacity is outdated; additional geothermal resource assessments have been published; and a new costing tool that incorporates current technology, engineering practices, and associated costs has been released.

  3. Working Memory Updating Latency Reflects the Cost of Switching between Maintenance and Updating Modes of Operation

    Science.gov (United States)

    Kessler, Yoav; Oberauer, Klaus

    2014-01-01

    Updating and maintenance of information are 2 conflicting demands on working memory (WM). We examined the time required to update WM (updating latency) as a function of the sequence of updated and not-updated items within a list. Participants held a list of items in WM and updated a variable subset of them in each trial. Four experiments that vary…

  4. Psoriasis: Pathogenesis, Assessment, and Therapeutic Update.

    Science.gov (United States)

    Schleicher, Stephen M

    2016-07-01

    Psoriasis is a chronic condition that affects more than 7 million Americans. This article explores the pathogenesis and physical signs of psoriasis. Over the past 2 decades enhanced understanding of the immunologic basis of psoriasis has led to the development of new systemic agents that have revolutionized the management of this disease, and these modalities, along with traditional therapies, are described.

  5. Malaysia - Productivity and Investment Climate Assessment Update

    OpenAIRE

    World Bank

    2009-01-01

    In the decades prior to the Asian financial crisis, the Malaysian economy experienced rapid growth and a significant structural transformation. It went from an economy that relied on agriculture and commodities to one dominated by manufacturing and services. Since then, however, Malaysia's growth has slowed to a level well below its key competitors in Asia, including the large labor-surplu...

  6. Memory updating and mental arithmetic

    Directory of Open Access Journals (Sweden)

    Cheng-Ching eHan

    2016-02-01

    Full Text Available Is domain-general memory updating ability predictive of calculation skills or are such skills better predicted by the capacity for updating specifically numerical information? Here, we used multidigit mental multiplication (MMM as a measure for calculating skill as this operation requires the accurate maintenance and updating of information in addition to skills needed for arithmetic more generally. In Experiment 1, we found that only individual differences with regard to a task updating numerical information following addition (MUcalc could predict the performance of MMM, perhaps owing to common elements between the task and MMM. In Experiment 2, new updating tasks were designed to clarify this: a spatial updating task with no numbers, a numerical task with no calculation, and a word task. The results showed that both MUcalc and the spatial task were able to predict the performance of MMM but only with the more difficult problems, while other updating tasks did not predict performance. It is concluded that relevant processes involved in updating the contents of working memory support mental arithmetic in adults.

  7. Adjustment or updating of models

    Indian Academy of Sciences (India)

    D J Ewins

    2000-06-01

    In this paper, first a review of the terminology used in the model adjustment or updating is presented. This is followed by an outline of the major updating algorithms cuurently available, together with a discussion of the advantages and disadvantages of each, and the current state-of-the-art of this important application and part of optimum design technology.

  8. 酒精戒断综合征:机制、评估及药物治疗进展%Alcohol Withdrawal Syndrome:Updates on Mechanism, Assessment and Pharmacotherapy

    Institute of Scientific and Technical Information of China (English)

    杨雪; 盛利霞; 郝伟; 汤宜朗

    2014-01-01

    Objective:To review the updates on mechanism of,and assessment and pharmacotherapy for alcohol Withdrawal syn-drome(AWS). Methods:Literature review and hand-picked literature. Results:We reviewed the time-course,mechanism(espe-cially mechanism related to GABA and NMDA systems),assessment and medications for AWS. Detailed discussions are provided re-garding fixed-dosed and symptom-triggered methods when using benzodiazepines for AWS. Role of other medications is also discussed. Conclusion:AWS is common and of diagnostic value in alcohol dependence. Alterations in GABA/ NMDA system after prolonged ex-posure to alcohol is believed to be the primary mechanism for AWS and long-acting benzodiazepines are the first-line pharmacotherapy, though other medications have been tried. Either fixed-dose or symptom-triggered method can be used,depending on the setting,clini-cians’preference and staff training.%目的:介绍酒精戒断综合征(AWS)的机制、评估及药物治疗方面的进展。方法:对近年相关文献进行复习。结果:本文对 AWS 的时程、机制(尤其是涉及 GABA 及 NMDA 递质系统)、评估及药物治疗进行了介绍。详细讨论了固定剂量法及对症给药法的具体细节。对其他药物的使用也略有介绍。结论:AWS 比较常见且对酒精将具有诊断意义。长期饮酒导致的GABA/ NMDA 系统的改变是 AWS 的主要机制,长效苯二氮□类药是控制 AWS 的一线药物,不过其他药物也有使用。具体是使用固定剂量法还是对症给药法则以治疗环境、医生的偏好以及员工的培训情况而定。

  9. FEM Updating of the Heritage Court Building Structure

    DEFF Research Database (Denmark)

    Ventura, C. E.; Brincker, Rune; Dascotte, E.

    2001-01-01

    . The starting model of the structure was developed from the information provided in the design documentation of the building. Different parameters of the model were then modified using an automated procedure to improve the correlation between measured and calculated modal parameters. Careful attention......This paper describes results of a model updating study conducted on a 15-storey reinforced concrete shear core building. The output-only modal identification results obtained from ambient vibration measurements of the building were used to update a finite element model of the structure...... was placed to the selection of the parameters to be modified by the updating software in order to ensure that the necessary changes to the model were realistic and physically realisable and meaningful. The paper highlights the model updating process and provides an assessment of the usefulness of using...

  10. Updates in ophthalmic pathology.

    Science.gov (United States)

    Mendoza, Pia R; Grossniklaus, Hans E

    2017-05-01

    Ophthalmic pathology has a long history and rich heritage in the field of ophthalmology. This review article highlights updates in ophthalmic pathology that have developed significantly through the years because of the efforts of committed individuals and the confluence of technology such as molecular biology and digital pathology. This is an exciting period in the history of ocular pathology, with cutting-edge techniques paving the way for new developments in diagnostics, therapeutics, and research. Collaborations between ocular oncologists and pathologists allow for improved and comprehensive patient care. Ophthalmic pathology continues to be a relevant specialty that is important in the understanding and clinical management of ocular disease, education of eye care providers, and overall advancement of the field.

  11. Amblyopia update: new treatments.

    Science.gov (United States)

    Vagge, Aldo; Nelson, Leonard B

    2016-09-01

    This review article is an update on the current treatments for amblyopia. In particular, the authors focus on the concepts of brain plasticity and their implications for novel treatment strategies for both children and adults affected by amblyopia. A variety of strategies has been developed to treat amblyopia in children and adults. New evidence on the pathogenesis of amblyopia has been obtained both in animal models and in clinical trials. Mainly, these studies have challenged the classical concept that amblyopia becomes untreatable after the 'end' of the sensitive or critical period of visual development, because of a lack of sufficient plasticity in the adult brain. New treatments for amblyopia in children and adults are desirable and should be encouraged. However, further studies should be completed before such therapies are widely accepted into clinical practice.

  12. Update on Parkinson disease.

    Science.gov (United States)

    Siderowf, Andrew; Stern, Matthew

    2003-04-15

    This Update reviews developments in the pathophysiology and treatment of Parkinson disease during the past several years. In the area of pathophysiology, studies have addressed the contribution of environmental factors such as caffeine and pesticides. Large-scale epidemiologic studies have also expanded the role genetic factors are thought to play. Detailed studies of kindreds with familial Parkinson disease due to alpha-synuclein and parkin have catalyzed basic science investigations into the pathologic mechanisms of the disease. These studies have led to the development of a pathophysiologic model of Parkinson disease that emphasizes abnormal protein aggregation. Studies of treatment have clarified the relative roles of l-dopa and dopamine agonists in early Parkinson disease and shown the potential for surgical interventions, particularly deep-brain stimulation, to relieve the symptoms of advanced, medically refractory disease.

  13. Y2K UPDATE

    CERN Multimedia

    Sverre JARP

    1999-01-01

    Concerning Y2K preparation, please note the following:Everybody, who has a NICE installation on his/her PC, needs to log in to NICE at least once before Xmas to get the Y2K update installed. This applies especially to dual boot systems.The test schedule on Y2Kplus.cern.ch will be prolonged. The last restart took place on 10 November and two more will take place on 24 November and 8 December, respectively. The Oracle users responsible for the maintenance of Oracle Forms applications which include PL/SQL blocks where date fields are handled with the default format are requested to contact oracle.support@cern.ch at their earliest convenience.Sverre Jarp (CERN Y2K co-ordinator, phone: 74944)

  14. ILRS Website Update

    Science.gov (United States)

    Noll, Carey E.; Torrence, Mark H.; Pollack, Nathan H.; Tyahla, Lori J.

    2013-01-01

    The ILRS website, http://ilrs.gsfc.nasa.gov, is the central source of information for all aspects of the service. The website provides information on the organization and operation of the ILRS and descriptions of ILRS components data, and products. Furthermore, the website provides an entry point to the archive of these data products available through the data centers. Links are provided to extensive information on the ILRS network stations including performance assesments and data quality evaluations. Descriptions of suported satellite missions (current, future, and past) are provided to aid in station acquisition and data analysis. The website was reently redesigned. Content was reviewed during the update process, ensuring information is current and useful. This poster will provide specific examples of key sections, applicaitons, and webpages.

  15. 浅析邓小平的民本思想%Analyses of Deng Xiao-ping’s Ideology of People's Departmentalism

    Institute of Scientific and Technical Information of China (English)

    苗伟伦

    2001-01-01

    Deng Xiao-ping didn’t clearly advance any anthropological the theory,but his view on human thought,especially the people's departmentalism has abandunt contents and distinct features. To learn and grasp this heritage is not only practical but also of historic significance.%邓小平虽然没有明确提出“人学”这一概念,但人的思想,尤其是人民本位思想内容丰富、特色鲜明。深刻学习和领会他的这份思想遗产具有重大的现实意义和深远的理论意义。

  16. Results of departmental plans for waste disposal and department-level detailed information; Bilan des plans departementaux d`elimination des dechets et informations detaillees par departement

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    1997-07-01

    Municipal and assimilated waste disposal departmental plans have been implemented in every French geographical department in order to generate a framework where collectivities can develop a waste management system. A comprehensive survey have been carried out on these programs, concerning burial site closures, waste sorting development, waste processing methodologies, equipment, investments, etc. It is shown that theses plans have induced a profound redevelopment of municipal waste management, generally with a multi- and complementary-process approach, but common industrial wastes are shown to be not very precisely integrated in the schemes. A waste up-grading ratio reaching 89 percent is appearing as the mean objective in these plans. The evolution of the number of waste disposal (burial, incineration, sorting...) centers is analyzed and the related investments are evaluated

  17. Pancreatitis. An update; Pankreatitis. Ein Update

    Energy Technology Data Exchange (ETDEWEB)

    Schreyer, A.G. [Universitaetsklinikum Regensburg, Institut fuer Roentgendiagnostik, Regensburg (Germany); Grenacher, L. [Diagnostik Muenchen, MVZ Radiologie, Muenchen (Germany); Juchems, M. [Klinikum Konstanz, Diagnostische und Interventionelle Radiologie, Konstanz (Germany)

    2016-04-15

    Acute and chronic pancreatitis are becoming increasingly more severe diseases in the western world with far-reaching consequences for the individual patient as well as the socioeconomic situation. This article gives an overview of the contribution of radiological imaging to the diagnostics and therapy of both forms of the disease. Acute pancreatitis can be subdivided into severe (20 %) and mild manifestations. The diagnostics should be performed with computed tomography (CT) or magnetic resonance imaging (MRI) for assessing necrosis or potential infections only in severe forms of pancreatitis. In chronic pancreatitis transabdominal ultrasound should initially be adequate for assessment of the pancreas. For the differential diagnosis between pancreatic carcinoma and chronic pancreatitis, MRI with magnetic resonance cholangiopancreatography (MRCP) followed by an endoscopic ultrasound-guided fine needle aspiration is the method of choice. For the primary diagnosis for acute and chronic pancreatitis ultrasound examination is the modality of first choice followed by radiological CT and MRI with MRCP examinations. (orig.) [German] Akute und chronische Pankreatitis sind in der westlichen Welt zunehmende schwere Krankheitsbilder mit tiefgreifenden Konsequenzen fuer den einzelnen Patienten sowie soziooekonomisch. Der Beitrag radiologischer Bildgebung zur Diagnostik und Therapie beider Erkrankungsformen soll im vorliegenden Uebersichtsbeitrag diskutiert werden. Die akute Pankreatitis kann in eine schwere (20 %) und milde Verlaufsform unterteilt werden. Lediglich bei den schweren Formen sollte eine CT- oder MRT-Diagnostik bzgl. der Beurteilung von Nekrosen und moeglichen Infektionen erfolgen. Bei der chronischen Pankreatitis genuegt zunaechst eine Beurteilung des Pankreas durch transabdominellen Ultraschall. Hier sind die MRT mit der Magnetresonanzcholangiopankreatikographie (MRCP) sowie die endosonographisch gesteuerte Feinnadelpunktion die Methode, um

  18. Update of CERN exchange network

    CERN Multimedia

    2003-01-01

    An update of the CERN exchange network will be done next April. Disturbances or even interruptions of telephony services may occur from 4th to 24th April during evenings from 18:30 to 00:00 but will not exceed more than 4 consecutive hours (see tentative planning below). CERN divisions are invited to avoid any change requests (set-ups, move or removals) of telephones and fax machines from 4th to 25th April. Everything will be done to minimize potential inconveniences which may occur during this update. There will be no loss of telephone functionalities. CERN GSM portable phones won't be affected by this change. Should you need more details, please send us your questions by email to Standard.Telephone@cern.ch. DateChange typeAffected areas April 11 Update of switch in LHC 4 LHC 4 Point April 14 Update of switch in LHC 5 LHC 5 Point April 15 Update of switches in LHC 3 and LHC 2 Points LHC 3 and LHC 2 April 22 Update of switch N4 Meyrin Ouest April 23 Update of switch  N6 Prévessin Site Ap...

  19. Multiplicative updates for the LASSO

    DEFF Research Database (Denmark)

    Mørup, Morten; Clemmensen, Line Katrine Harder

    2007-01-01

    .e. least squares minimization with $L_1$-norm regularization, since the multiplicative updates (MU) can efficiently exploit the structure of the problem traditionally solved using quadratic programming (QP). We derive an algorithm based on MU for the LASSO and compare the performance to Matlabs standard QP......Multiplicative updates have proven useful for non-negativity constrained optimization. Presently, we demonstrate how multiplicative updates also can be used for unconstrained optimization. This is for instance useful when estimating the least absolute shrinkage and selection operator (LASSO), i...

  20. Advanced Stirling Convertor Update

    Science.gov (United States)

    Wood, J. Gary; Carroll, Cliff; Matejczyk, Dan; Penswick, L. B.; Soendker, E.

    2006-01-01

    This paper reports on the 88 We Advanced Stirling Convertor (ASC) currently being developed under Phase II of a NASA NRA program for possible use in advanced high specific power radioisotope space power systems. An early developmental unit, the Frequency Test Bed (FTB) which was built and tested in Phase I demonstrated 36% efficiency. The ASC-1 currently being developed under Phase II, uses a high temperature heater head to allow for operation at 850 °C and is expected to have an efficiency approaching 40% (based on AC electrical out) at a temperature ratio of 3.1. The final lightweight ASC-2 convertor to be developed in Phase III is expected to have a mass of approximately 1 kg. The implementation of the ASC would allow for much higher specific power radioisotope power systems, requiring significantly less radioisotope fuel than current systems. The first run of the ASC-1 occurred in September 2005, and full temperature operation was achieved in early October 2005. Presented is an update on progress on the ASC program as well as the plans for future development. Also presented are efforts being performed to ensure the ASC has the required long life already demonstrated in free-piston Stirling cryocoolers.

  1. Gearbox Reliability Collaborative Update (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Sheng, S.; Keller, J.; Glinsky, C.

    2013-10-01

    This presentation was given at the Sandia Reliability Workshop in August 2013 and provides information on current statistics, a status update, next steps, and other reliability research and development activities related to the Gearbox Reliability Collaborative.

  2. Email Updates: MedlinePlus

    Science.gov (United States)

    ... of this page: https://medlineplus.gov/listserv.html Email Updates To use the sharing features on this ... view your email history or unsubscribe. Prevent MedlinePlus emails from being marked as "spam" or "junk" To ...

  3. 77 FR 13198 - Product List Update

    Science.gov (United States)

    2012-03-06

    ...] Product List Update AGENCY: Postal Regulatory Commission. ACTION: Final rule. SUMMARY: The Commission is... adopted in a recent Commission order. The referenced policy assumes periodic updates. The updates are... these updates. DATES: Effective Date: March 6, 2012. Applicability Dates: February 23, 2012...

  4. 75 FR 39629 - FOIA Fee Schedule Update

    Science.gov (United States)

    2010-07-12

    ... 1703 FOIA Fee Schedule Update AGENCY: Defense Nuclear Facilities Safety Board. ACTION: Establishment of... Information Act (FOIA) Fee Schedule Update pursuant to 10 CFR 1703.107(b)(6) of the Board's regulations. DATES... update the FOIA Fee Schedule once every 12 months. The previous Fee Schedule Update was published in...

  5. Update on fungemia in oncology and hematology.

    Science.gov (United States)

    Carreras, Enric; Vázquez, Lourdes; Rodríguez Tudela, José Luis; Pahisa, Albert; Azanza, José Ramón; Rovira, Montserrat; de la Cámara, Rafael

    2011-03-01

    The present article is an update of the literature on fungemia in onco-hematologic patients. A multidisciplinary group of Spanish physicians with an interest in this field selected the most important papers published lately. Papers from the fields of epidemiology, risk factors, pathogenesis, diagnosis, outcome, prevention and treatment are discussed. Important aspects of these studies include the assessment of different strategies in the management of fever in neutropenic patients. Moreover, early identification of patients at risk of fungal infections, as well as identification of patients at risk for fluconazole-resistant strains are topics of increasing interest.

  6. Communication technology update and fundamentals

    CERN Document Server

    Grant, August E

    2008-01-01

    New communication technologies are being introduced at an astonishing rate. Making sense of these technologies is increasingly difficult. Communication Technology Update is the single best source for the latest developments, trends, and issues in communication technology. Now in its 11th edition, Communication Technology Update has become an indispensable information resource for business, government, and academia. As always, every chapter has been completely rewritten to reflect the latest developments and market statistics, and now covers mobile computing, dig

  7. Communication technology update and fundamentals

    CERN Document Server

    Grant, August E

    2010-01-01

    New communication technologies are being introduced at an astonishing rate. Making sense of these technologies is increasingly difficult. Communication Technology Update and Fundamentals is the single best source for the latest developments, trends, and issues in communication technology. Featuring the fundamental framework along with the history and background of communication technologies, Communication Technology Update and Fundamentals, 12th edition helps you stay ahead of these ever-changing and emerging technologies.As always, every chapter ha

  8. Episodic fieldwork, updating, and sociability

    DEFF Research Database (Denmark)

    Whyte, M.

    2013-01-01

    on these relationships. I draw on Simmel's concept of sociability to explore the significance of the recurring updates that are so much a part of long-term and thus episodic fieldwork. Updating suggests participation, positionality, and transformation-as well as play and familiarity. The presumption of familiarity......, which is at the heart of sociability, becomes a tool for exploring time and new social experiences and the ways in which chronology is interwoven with shifting social positions....

  9. Decentralized Consistent Updates in SDN

    KAUST Repository

    Nguyen, Thanh Dang

    2017-04-10

    We present ez-Segway, a decentralized mechanism to consistently and quickly update the network state while preventing forwarding anomalies (loops and blackholes) and avoiding link congestion. In our design, the centralized SDN controller only pre-computes information needed by the switches during the update execution. This information is distributed to the switches, which use partial knowledge and direct message passing to efficiently realize the update. This separation of concerns has the key benefit of improving update performance as the communication and computation bottlenecks at the controller are removed. Our evaluations via network emulations and large-scale simulations demonstrate the efficiency of ez-Segway, which compared to a centralized approach, improves network update times by up to 45% and 57% at the median and the 99th percentile, respectively. A deployment of a system prototype in a real OpenFlow switch and an implementation in P4 demonstrate the feasibility and low overhead of implementing simple network update functionality within switches.

  10. Dutch Venous Ulcer guideline update.

    Science.gov (United States)

    Maessen-Visch, M Birgitte; de Roos, Kees-Peter

    2014-05-01

    The revised guideline of 2013 is an update of the 2005 guideline "venous leg ulcer". In this special project four separate guidelines (venous leg ulcer, varicose veins, compression therapy and deep venous disorders) were revised and developed simultaneously. A meeting was held including representatives of any organisation involved in venous disease management including patient organizations and health insurance companies. Eighteen clinical questions where defined, and a new strategy was used to accelerate the process. This resulted in two new and two revised guidelines within one year. The guideline committee advises use of the C of the CEAP classification as well as the Venous Clinical Severity Score (VCSS) and a Quality of life (QoL) score in the assessment of clinical signs. These can provide insight into the burden of disease and the effects of treatment as experienced by the patient. A duplex ultrasound should be performed in every patient to establish the underlying aetiology and to evaluate the need for treatment (which is discussed in a separate guideline). The use of the TIME model for describing venous ulcers is recommended. There is no evidence for antiseptic or antibiotic wound care products except for a Cochrane review in which some evidence is presented for cadexomer iodine. Signs of infection are the main reason for the use of oral antibiotics. When the ulcer fails to heal the use of oral aspirin and pentoxifylline can be considered as an adjunct. For the individual patient, the following aspects should be considered: the appearance of the ulcer (amount of exudate) according to the TIME model, the influence of wound care products on moisturising the wound, frequency of changing compression bandages, pain and allergies. The cost of the dressings should also be considered. Education and training of patients t improves compliance with compression therapy but does not influence wound healing rates.

  11. VIIP 2017 Clinical Update

    Science.gov (United States)

    Tarver, William

    2017-01-01

    INTRODUCTION: NASA's Space Medicine community knowledge regarding the "Vision Impairment Intracranial Pressure", or VIIP.has been evolving over time.. Various measures of occupational health related to this condition had to be determined and then plans/processes put into place. The most robust of these processes were inititated in 2010. This presentation will provide a clinic update of the astronaut occupational health data related to VIIP. METHODS: NASA and its international partners require its astronauts to undergo routine health measures deemed important to monitoring VIIP. The concern is that the spaceflight environment aboard ISS could cause some astronauts to have physiologic changes detrimental to either ongoing mission operations or long-term health related to the ocular system and possibly the CNS. Specific medical tests include but are not limited to brain/orbit MRI (NASA unique protocol), OCT, fundoscopy and ocular ultrasound. Measures are taken prior to spaceflight, in-flight and post-flight. Measures to be reported include incidence of disc edema, globe flattening, choroidal folds, ONSD and change in refractive error. RESULTS: 73 ISS astronauts have been evaluated at least partially for VIIP related measures. Of these individuals, approximately 1 in 7 have experienced disc edema. The prevalence of the other findings is more complicated as the medical testing has changed over time. Overall, 26 separate individuals have experienced at least one of the findings NASA has associated with VIIP Another confounding factor is most of the astronauts have prior spaceflight experience at the time of the "pre-flight" testing. DISCUSSION: In 2010 NASA and its US operating segment (USOS) partners (CSA, ESA and JAXA) began routine occupational monitoring and data collection for most VIIP related changes. Interpretation of that data is extremely challenging for several reasons. For example, the determination of disc edema is the most complete finding as we have had

  12. How to Green Windows Update?

    Directory of Open Access Journals (Sweden)

    Seifedine Kadry

    2012-11-01

    Full Text Available The most important challenges facing the earth in the future are energy, water, environment and food security, Green IT contributes in significant role in finding solutions because it consume energy more efficient and reduce pollution in water, air and soil in addition to improving economy because Green IT is manage energy sources by reducing energy consumption with good performance. Most of energy consumed around the world depends on non-renewable energy and part of this energy consumed to update technologies In this paper ,we will study one of the most important tools in Microsoft, which is used in order to help users to get updates of Microsoft's products, which is called windows server update services (WSUS, which is helping to reduce energy consumption, we will study this tool and then try to make it more green by reducing the send / receive between Microsoft Update (MU and WSUS, which will reduce energy consumption, and we will propose algorithm and compared the energy consumption in the current design with energy consumption in the proposed design. This design will open the way for future work in order to make sending updates in MU less energy consumption by apply conditional sending and that will help to improve the performance of MU added to improve the network performance with more efficient consumption of energy.

  13. NASA ESTO Lidar Technologies Investment Strategy: 2016 Decadal Update

    Science.gov (United States)

    Valinia, Azita; Komar, George J.; Tratt, David M.; Lotshaw, William T.; Gaab, Kevin M.

    2017-01-01

    The NASA Earth Science Technology Office (ESTO) recently updated its investment strategy in the area of lidar technologies as it pertains to NASA's Earth Science measurement goals in the next decade. The last ESTO lidar strategy was documented in 2006. The current (2016) report assesses the state-of-the-art in lidar technologies a decade later. Lidar technology maturation in the past decade has been evaluated, and the ESTO investment strategy is updated and laid out in this report according to current NASA Earth science measurement needs and new emerging technologies.

  14. Updated NGNP Fuel Acquisition Strategy

    Energy Technology Data Exchange (ETDEWEB)

    David Petti; Tim Abram; Richard Hobbins; Jim Kendall

    2010-12-01

    A Next Generation Nuclear Plant (NGNP) fuel acquisition strategy was first established in 2007. In that report, a detailed technical assessment of potential fuel vendors for the first core of NGNP was conducted by an independent group of international experts based on input from the three major reactor vendor teams. Part of the assessment included an evaluation of the credibility of each option, along with a cost and schedule to implement each strategy compared with the schedule and throughput needs of the NGNP project. While credible options were identified based on the conditions in place at the time, many changes in the assumptions underlying the strategy and in externalities that have occurred in the interim requiring that the options be re-evaluated. This document presents an update to that strategy based on current capabilities for fuel fabrication as well as fuel performance and qualification testing worldwide. In light of the recent Pebble Bed Modular Reactor (PBMR) project closure, the Advanced Gas Reactor (AGR) fuel development and qualification program needs to support both pebble and prismatic options under the NGNP project. A number of assumptions were established that formed a context for the evaluation. Of these, the most important are: • Based on logistics associated with the on-going engineering design activities, vendor teams would start preliminary design in October 2012 and complete in May 2014. A decision on reactor type will be made following preliminary design, with the decision process assumed to be completed in January 2015. Thus, no fuel decision (pebble or prismatic) will be made in the near term. • Activities necessary for both pebble and prismatic fuel qualification will be conducted in parallel until a fuel form selection is made. As such, process development, fuel fabrication, irradiation, and testing for pebble and prismatic options should not negatively influence each other during the period prior to a decision on reactor type

  15. Updated safety analysis of ITER

    Energy Technology Data Exchange (ETDEWEB)

    Taylor, Neill, E-mail: neill.taylor@iter.org [ITER Organization, CS 90 046, 13067 St Paul Lez Durance Cedex (France); Baker, Dennis; Ciattaglia, Sergio; Cortes, Pierre; Elbez-Uzan, Joelle; Iseli, Markus; Reyes, Susana; Rodriguez-Rodrigo, Lina; Rosanvallon, Sandrine; Topilski, Leonid [ITER Organization, CS 90 046, 13067 St Paul Lez Durance Cedex (France)

    2011-10-15

    An updated version of the ITER Preliminary Safety Report has been produced and submitted to the licensing authorities. It is revised and expanded in response to requests from the authorities after their review of an earlier version in 2008, to reflect enhancements in ITER safety provisions through design changes, to incorporate new and improved safety analyses and to take into account other ITER design evolution. The updated analyses show that changes to the Tokamak cooling water system design have enhanced confinement and reduced potential radiological releases as well as removing decay heat with very high reliability. New and updated accident scenario analyses, together with fire and explosion risk analyses, have shown that design provisions are sufficient to minimize the likelihood of accidents and reduce potential consequences to a very low level. Taken together, the improvements provided a stronger demonstration of the very good safety performance of the ITER design.

  16. Does updating improve the methodological and reporting quality of systematic reviews?

    Directory of Open Access Journals (Sweden)

    Hamel Candyce

    2006-06-01

    Full Text Available Abstract Background Systematic reviews (SRs must be of high quality. The purpose of our research was to compare the methodological and reporting quality of original versus updated Cochrane SRs to determine whether updating had improved these two quality dimensions. Methods We identifed updated Cochrane SRs published in issue 4, 2002 of the Cochrane Library. We assessed the updated and original versions of the SRs using two instruments: the 10 item enhanced Overview Quality Assessment Questionnaire (OQAQ, and an 18-item reporting quality checklist and flow chart based upon the Quality of Reporting of Meta-analyses (QUOROM statement. At least two reviewers extracted data and assessed quality. We calculated the percentage (with a 95% confidence interval of 'yes' answers to each question. We calculated mean differences in percentage, 95% confidence intervals and p-values for each of the individual items and the overall methodological quality score of the updated and pre-updated versions using OQAQ. Results We assessed 53 SRs. There was no significant improvement in the global quality score of the OQAQ (mean difference 0.11 (-0.28; 0.70 p = 0.52. Updated reviews showed a significant improvement of 18.9 (7.2; 30.6 p Conclusion The overall quality of Cochrane SRs is fair-to-good. Although reporting quality improved on certain individual items there was no overall improvement seen with updating and methodological quality remained unchanged. Further improvement of quality of reporting is possible. There is room for improvement of methodological quality as well. Authors updating reviews should address identified methodological or reporting weaknesses. We recommend to give full attention to both quality domains when updating SRs.

  17. Online Updating of Statistical Inference in the Big Data Setting.

    Science.gov (United States)

    Schifano, Elizabeth D; Wu, Jing; Wang, Chun; Yan, Jun; Chen, Ming-Hui

    2016-01-01

    We present statistical methods for big data arising from online analytical processing, where large amounts of data arrive in streams and require fast analysis without storage/access to the historical data. In particular, we develop iterative estimating algorithms and statistical inferences for linear models and estimating equations that update as new data arrive. These algorithms are computationally efficient, minimally storage-intensive, and allow for possible rank deficiencies in the subset design matrices due to rare-event covariates. Within the linear model setting, the proposed online-updating framework leads to predictive residual tests that can be used to assess the goodness-of-fit of the hypothesized model. We also propose a new online-updating estimator under the estimating equation setting. Theoretical properties of the goodness-of-fit tests and proposed estimators are examined in detail. In simulation studies and real data applications, our estimator compares favorably with competing approaches under the estimating equation setting.

  18. Nephrogenic systemic fibrosis: epidemiology update

    DEFF Research Database (Denmark)

    Marckmann, P.

    2008-01-01

    Purpose of review The aim of this article is to outline the history of nephrogenic systemic fibrosis, a new and serious disease of patients with renal failure, and to give an update on its aetiology and prevalence. Recent findings Epidemiological and histochemical studies demonstrated that gadoli......Purpose of review The aim of this article is to outline the history of nephrogenic systemic fibrosis, a new and serious disease of patients with renal failure, and to give an update on its aetiology and prevalence. Recent findings Epidemiological and histochemical studies demonstrated...

  19. Clinical Voices - an update

    DEFF Research Database (Denmark)

    Fusaroli, Riccardo; Weed, Ethan

    Anomalous aspects of speech and voice, including pitch, fluency, and voice quality, are reported to characterise many mental disorders. However, it has proven difficult to quantify and explain this oddness of speech by employing traditional statistical methods. In this talk we will show how the t...... the temporal dynamics of the voice in Asperger's patients enable us to automatically reconstruct the diagnosis, and assess the Autism quotient score. We then generalise the findings to Danish and American children with autism....

  20. CTL Model Update for System Modifications

    CERN Document Server

    Ding, Yulin; Zhang, Yan; Zhang, Y; 10.1613/jair.2420

    2011-01-01

    Model checking is a promising technology, which has been applied for verification of many hardware and software systems. In this paper, we introduce the concept of model update towards the development of an automatic system modification tool that extends model checking functions. We define primitive update operations on the models of Computation Tree Logic (CTL) and formalize the principle of minimal change for CTL model update. These primitive update operations, together with the underlying minimal change principle, serve as the foundation for CTL model update. Essential semantic and computational characterizations are provided for our CTL model update approach. We then describe a formal algorithm that implements this approach. We also illustrate two case studies of CTL model updates for the well-known microwave oven example and the Andrew File System 1, from which we further propose a method to optimize the update results in complex system modifications.

  1. Wind turbine reliability database update.

    Energy Technology Data Exchange (ETDEWEB)

    Peters, Valerie A.; Hill, Roger Ray; Stinebaugh, Jennifer A.; Veers, Paul S.

    2009-03-01

    This report documents the status of the Sandia National Laboratories' Wind Plant Reliability Database. Included in this report are updates on the form and contents of the Database, which stems from a fivestep process of data partnerships, data definition and transfer, data formatting and normalization, analysis, and reporting. Selected observations are also reported.

  2. Upgrade trigger: Biannual performance update

    CERN Document Server

    Aaij, Roel; Couturier, Ben; Esen, Sevda; De Cian, Michel; De Vries, Jacco Andreas; Dziurda, Agnieszka; Fitzpatrick, Conor; Fontana, Marianna; Grillo, Lucia; Hasse, Christoph; Jones, Christopher Rob; Le Gac, Renaud; Matev, Rosen; Neufeld, Niko; Nikodem, Thomas; Polci, Francesco; Del Buono, Luigi; Quagliani, Renato; Schwemmer, Rainer; Seyfert, Paul; Stahl, Sascha; Szumlak, Tomasz; Vesterinen, Mika Anton; Wanczyk, Joanna; Williams, Mark Richard James; Yin, Hang; Zacharjasz, Emilia Anna

    2017-01-01

    This document presents the performance of the LHCb Upgrade trigger reconstruction sequence, incorporating changes to the underlying reconstruction algorithms and detector description since the Trigger and Online Upgrade TDR. An updated extrapolation is presented using the most recent example of an Event Filter Farm node.

  3. Mozambique Economic Update, December 2016

    OpenAIRE

    2016-01-01

    This Mozambique economic update brief for 2016 includes a section on recent economic developments and a discussion of Mozambique’s economic outlook, followed by focus section(s) analyzing issues of particular importance.This has been a testing year for Mozambique. An ongoing downturn, brought about by low commodity prices, drought and conflict, was compounded by the fallout from the discov...

  4. Bangladesh Development Update, October 2016

    OpenAIRE

    2016-01-01

    This update introduces Bangladesh's new poverty numbers at $1.90 per capita per day in 2011 purchasing power parity (PPP) prices, followed by an account of recent economic development, the outlook, risks, and policy responses. The revised poverty rates are significantly lower, but follow the same downward historical trend seen when using the 2005 international extreme poverty line. Banglad...

  5. Anterior cruciate ligament - updating article

    Directory of Open Access Journals (Sweden)

    Marcus Vinicius Malheiros Luzo

    2016-08-01

    Full Text Available ABSTRACT This updating article on the anterior cruciate ligament (ACL has the aim of addressing some of the most interesting current topics in this field. Within this stratified approach, it contains the following sections: ACL remnant; anterolateral ligament and combined intra and extra-articular reconstruction; fixation devices; and ACL femoral tunnel creation techniques.

  6. Evidence-based guideline update

    DEFF Research Database (Denmark)

    Tfelt-Hansen, Peer Carsten

    2013-01-01

    Peer Carsten Tfelt-Hansen, Glostrup, Denmark: According to the recent American Academy of Neurology (AAN) guideline update, a drug can be recommended as possibly effective for migraine prevention if it had demonstrated efficacy in one Class II study.(1) Eight drugs are recommended as possibly...

  7. Update of CERN exchange network

    CERN Multimedia

    2003-01-01

    An update of the CERN exchange network will be done next April. Disturbances or even interruptions of telephony services may occur from 4th to 24th April during evenings from 18:30 to 00:00 but will not exceed more than 4 consecutive hours (see tentative planning below). In addition, the voice messaging system will be shut down on March, 26th April from 18:00 to 00:00. Calls supposed to be routed to the voice messaging system will not be possible during the shutdown. CERN divisions are invited to avoid any change requests (set-ups, move or removals) of telephones and fax machines from 4th to 25th April. Everything will be done to minimize potential inconveniences which may occur during this update. There will be no loss of telephone functionalities. CERN GSM portable phones won't be affected by this change. Should you need more details, please send us your questions by email to Standard.Telephone@cern.ch. Date Change type Affected areas April 8 Update of switch in LHC 7 LHC 7 Point April 9 Update of...

  8. Update of CERN exchange network

    CERN Multimedia

    2003-01-01

    An update of the CERN exchange network will be done next April. Disturbances or even interruptions of telephony services may occur from 4th to 24th April during evenings from 18:30 to 00:00 but will not exceed more than 4 consecutive hours (see tentative planning below). In addition, the voice messaging system will be shut down on March, 26th April from 18:00 to 00:00. Calls supposed to be routed to the voice messaging system will not be possible during the shutdown. CERN divisions are invited to avoid any change requests (set-ups, move or removals) of telephones and fax machines from 4th to 25th April. Everything will be done to minimize potential inconveniences which may occur during this update. There will be no loss of telephone functionalities. CERN GSM portable phones won't be affected by this change. Should you need more details, please send us your questions by email to Standard.Telephone@cern.ch. DateChange typeAffected areas March 26Update of the voice messaging systemAll CERN sites April 4Updat...

  9. AMDIS and CHART update. 1

    Energy Technology Data Exchange (ETDEWEB)

    Murakami, I.; Kato, T. [National Inst. for Fusion Science, Toki, Gifu (Japan); Igarashi, A. [Miyazaki Univ., Miyazaki (JP)] [and others

    2002-10-01

    A working group for updating atomic and molecular collision data in the NIFS database AMDIS (electron scattering) and CHART (ion scattering) has been organized. This group has searched and reviewed literatures for collecting relevant atomic data with are to be included into the database. This is a summary report of the activities of this working group. (author)

  10. A Mathematics Software Database Update.

    Science.gov (United States)

    Cunningham, R. S.; Smith, David A.

    1987-01-01

    Contains an update of an earlier listing of software for mathematics instruction at the college level. Topics are: advanced mathematics, algebra, calculus, differential equations, discrete mathematics, equation solving, general mathematics, geometry, linear and matrix algebra, logic, statistics and probability, and trigonometry. (PK)

  11. Legal Update of Gifted Education

    Science.gov (United States)

    Zirkel, Perry A.

    2016-01-01

    This update of the legislation/regulations and case law specific to pre-K-12 gifted students since a cluster of publications in 2004-2005 primarily focuses on the "gifted alone" category, with only secondary attention to twice-exceptional and other students in the "gifted plus" category. For the gifted-alone category, the…

  12. Eczema and ceramides: an update

    DEFF Research Database (Denmark)

    Jungersted, Jakob Mutanu; Agner, Tove

    2013-01-01

    types of treatment. We also consider the genetic influence on stratum corneum lipids. The review is an update on research indexed in PubMed following the discovery of the filaggrin mutations in atopic dermatitis in 2006, but when newer publications cannot stand alone, we include publications from before...

  13. NACRE Update and Extension Project

    Science.gov (United States)

    Aikawa, Masayuki; Arai, Koji; Arnould, Marcel; Takahashi, Kohji; Utsunomiya, Hiroaki

    2006-04-01

    NACRE, the `nuclear astrophysics compilation of reaction rates', has been widely utilized in stellar evolution and nucleosynthesis studies since its publication in 1999. We describe here the current status of a Konan-Université Libre de Bruxelles (ULB) joint project that aims at its update and extension.

  14. Anterior cruciate ligament - updating article.

    Science.gov (United States)

    Luzo, Marcus Vinicius Malheiros; Franciozi, Carlos Eduardo da Silveira; Rezende, Fernando Cury; Gracitelli, Guilherme Conforto; Debieux, Pedro; Cohen, Moisés

    2016-01-01

    This updating article on the anterior cruciate ligament (ACL) has the aim of addressing some of the most interesting current topics in this field. Within this stratified approach, it contains the following sections: ACL remnant; anterolateral ligament and combined intra and extra-articular reconstruction; fixation devices; and ACL femoral tunnel creation techniques.

  15. Model validation: Correlation for updating

    Indian Academy of Sciences (India)

    D J Ewins

    2000-06-01

    In this paper, a review is presented of the various methods which are available for the purpose of performing a systematic comparison and correlation between two sets of vibration data. In the present case, the application of interest is in conducting this correlation process as a prelude to model correlation or updating activity.

  16. Belief update as social choice

    NARCIS (Netherlands)

    van Benthem, J.; Girard, P.; Roy, O.; Marion, M.

    2011-01-01

    Dynamic epistemic-doxastic logics describe the new knowledge or new beliefs indexBelief of agents after some informational event has happened. Technically, this requires an update rule that turns a doxastic-epistemic modelM(recording the current information state of the agents) and a dynamic ‘event

  17. JPSS CGS Tools For Rapid Algorithm Updates

    Science.gov (United States)

    Smith, D. C.; Grant, K. D.

    2011-12-01

    Northrop Grumman have developed tools and processes to enable changes to be evaluated, tested, and moved into the operational baseline in a rapid and efficient manner. This presentation will provide an overview of the tools available to the Cal/Val teams to ensure rapid and accurate assessment of algorithm changes, along with the processes in place to ensure baseline integrity. [1] K. Grant and G. Route, "JPSS CGS Tools for Rapid Algorithm Updates," NOAA 2011 Satellite Direct Readout Conference, Miami FL, Poster, Apr 2011. [2] K. Grant, G. Route and B. Reed, "JPSS CGS Tools for Rapid Algorithm Updates," AMS 91st Annual Meeting, Seattle WA, Poster, Jan 2011. [3] K. Grant, G. Route and B. Reed, "JPSS CGS Tools for Rapid Algorithm Updates," AGU 2010 Fall Meeting, San Francisco CA, Oral Presentation, Dec 2010.

  18. Crayfish distribution updating in central Italy

    Directory of Open Access Journals (Sweden)

    M. Scalici

    2009-01-01

    Full Text Available Introductions of non-indigenous crayfish have received great attention from biologists and policy makers during the last decade. Purposes of this study are to update the knowledge about the crayfish distribution in Latium (central Italy, and to show how interactions between indigenous and non-indigenous species can affect their distribution. The main findings of this study were (1 the great decrease of the Austropotamobius pallipes populations and (2 the alarming spread of the four non-indigenous species red swamp crayfish Procambarus clarkii (the main widespread crayfish, spiny-cheek crayfish Orconectes limosus, narrow-clawed crayfish Astacus leptodactylus, and yabby Cherax destructor. We never observed indigenous and non-indigenous crayfish living in syntopy, although we noted that white-clawed crayfish had become extinct at sites where non-indigenous crayfish species exist now. Other type of problems (i.e. illegal harvesting and over-abstraction of water for human use can also reduce the distribution and abundance of the indigenous crayfish stocks. The distribution of Italian crayfish populations has not been studied sufficiently and more studies are required nationwide to assess the conservation status of A. pallipes and the occurrence of non-indigenous species. A national database of crayfish records ought to be constructed and regularly updated.

  19. 75 FR 70124 - Product List Update

    Science.gov (United States)

    2010-11-17

    ... 30 CFR Part 3020 Product List Update AGENCY: Postal Regulatory Commission. ACTION: Final rule... Commission order. The referenced policy assumes periodic updates. The updates are identified in the body of this document. The product lists, which are re-published in their entirety, include these...

  20. 76 FR 1357 - Product List Update

    Science.gov (United States)

    2011-01-10

    ... 30 CFR Part 3020 Product List Update AGENCY: Postal Regulatory Commission. ACTION: Final rule... Commission order. The referenced policy assumes periodic updates. The updates are identified in the body of this document. The product lists, which are re-published in their entirety, include these...

  1. 77 FR 41258 - FOIA Fee Schedule Update

    Science.gov (United States)

    2012-07-13

    ... SAFETY BOARD 10 CFR Part 1703 FOIA Fee Schedule Update AGENCY: Defense Nuclear Facilities Safety Board... publishing its Freedom of Information Act (FOIA) Fee Schedule Update pursuant to the Board's regulations..., the Board's General Manager will update the FOIA Fee Schedule once every 12 months. The previous...

  2. 76 FR 43819 - FOIA Fee Schedule Update

    Science.gov (United States)

    2011-07-22

    ... SAFETY BOARD 10 CFR Part 1703 FOIA Fee Schedule Update AGENCY: Defense Nuclear Facilities Safety Board... publishing its Freedom of Information Act (FOIA) Fee Schedule Update pursuant to the Board's regulations... General Manager will update the FOIA Fee Schedule once every 12 months. The previous Fee Schedule...

  3. 76 FR 9648 - Product List Update

    Science.gov (United States)

    2011-02-22

    ... 39 CFR Part 3020 Product List Update AGENCY: Postal Regulatory Commission. ACTION: Final rule... Commission order. The referenced policy assumes periodic updates. The updates are identified in the body of this document. The product lists, which are re-published in their entirety, include these...

  4. 77 FR 75377 - Product List Update

    Science.gov (United States)

    2012-12-20

    ... 39 CFR Part 3020 Product List Update AGENCY: Postal Regulatory Commission. ACTION: Final rule... Commission order. The referenced policy assumes periodic updates. The updates are identified in the body of this document. The product lists, which are re-published in their entirety, include these...

  5. Assessment

    Institute of Scientific and Technical Information of China (English)

    Geoff Brindley

    2005-01-01

    @@ Introduction TERMINOLOGY AND KEY CONCEPTS The term assessment refers to a variety of ways of collecting information on a learner's language ability or achievement. Although testing and assessment are often used interchangeably, the latter is an umbrella term encompassing measurement instruments administered on a ‘one-off’ basis such as tests, as well as qualitative methods of monitoring and recording student learning such as observation, simulations of project work. Assessment is also distinguished from evaluation which is concerned with the overall language programme and not just with what individual students have learnt. Proficiency assessment refers to the assessment of general language abilities acquired by the learner independent of a course of study.This kind of assessment is often done through the administration of standardised commercial language-proficency tests. On the other hand, assessment of achievement aims to establish what a student had learned in relation to a particular course or curriculum (thus frequently carried out by the teacher) .Achievement assesssment may be based either on the specific content of the course or on the course objectives (Hughes 1989).

  6. Wet storage integrity update

    Energy Technology Data Exchange (ETDEWEB)

    Bailey, W.J.; Johnson, A.B. Jr.

    1983-09-01

    This report includes information from various studies performed under the Wet Storage Task of the Spent Fuel Integrity Project of the Commercial Spent Fuel Management (CSFM) Program at Pacific Northwest Laboratory. An overview of recent developments in the technology of wet storage of spent water reactor fuel is presented. Licensee Event Reports pertaining to spent fuel pools and the associated performance of spent fuel and storage components during wet storage are discussed. The current status of fuel that was examined under the CSFM Program is described. Assessments of the effect of boric acid in spent fuel pool water on the corrosion and stress corrosion cracking of stainless steel and the stress corrosion cracking of stainless steel piping containing stagnant water at spent fuel pools are discussed. A list of pertinent publications is included. 84 references, 21 figures, 11 tables.

  7. Alzheimer disease update.

    Science.gov (United States)

    Matthews, Brandy R

    2010-04-01

    Alzheimer disease (AD) is a progressive neurodegenerative disorder affecting more than 37 million people worldwide and increasing in incidence based on its primary risk factor, advancing age. A growing body of knowledge regarding amyloid and tau neuropathology, genetic and environmental risk modifiers, early and atypical clinical presentations, and the use of symptom-modifying medical and psychosocial therapies is available to aid in the diagnosis and management of patients with AD. Exciting recent advances in neurobiology render the areas of genetic susceptibility, biomarkers for early disease detection and assessment of disease progression, and novel therapeutic strategies to modify the natural history of the disease compelling, but in need of further study before implementation into routine clinical practice is feasible.

  8. Finite element model updating of existing steel bridge based on structural health monitoring

    Institute of Scientific and Technical Information of China (English)

    HE Xu-hui; YU zhi-wu; CHEN Zheng-qing

    2008-01-01

    Based on the physical meaning of sensitivity, a new finite element (FE) model updating method was proposed. In this method, a three-dimensional FE model of the Nanjing Yangtze River Bridge (NYRB) with ANSYS program was established and updated by modifying some design parameters. To further validate the updated FE model, the analytical stress-time histories responses of main members induced by a moving train were compared with the measured ones. The results show that the relative error of maximum stress is 2.49% and the minimum relative coefficient of analytical stress-time histories responses is 0.793. The updated model has a good agreement between the calculated data and the tested data, and provides a current baseline FE model for long-term health monitoring and condition assessment of the NYRB. At the same time, the model is validated by stress-time histories responses to be feasible and practical for railway steel bridge model updating.

  9. Strategies for monitoring and updating clinical practice guidelines: a systematic review

    Directory of Open Access Journals (Sweden)

    Martínez García Laura

    2012-11-01

    Full Text Available Abstract Background Scientific knowledge is in constant change. The flow of new information requires a frequent re-evaluation of the available research results. Clinical practice guidelines (CPGs are not exempted from this phenomenon and need to be kept updated to maintain the validity of their recommendations. The objective of our review is to systematically identify, describe and assess strategies for monitoring and updating CPGs. Study design and setting We conducted a systematic review of studies evaluating one or more methods of updating (with or without monitoring CPGs or recommendations. We searched MEDLINE (PubMed and The Cochrane Methodology Register (The Cochrane Library from 1966 to June 2012. Additionally, we hand-searched reference lists of the included studies and the Guidelines International Network book of abstracts. If necessary, we contacted study authors to obtain additional information. Results We included a total of eight studies. Four evaluated if CPGs were out of date, three updated CPGs, and one continuously monitored and updated CPGs. The most detailed reported phase of the process was the identification of new evidence. As opposed to studies updating guidelines, studies evaluating if CPGs were out of date applied restricted searches. Only one study compared a restricted versus an exhaustive search suggesting that a restricted search is sufficient to assess recommendations’ Validity. One study analyzed the survival time of CPGs and suggested that these should be reassessed every three years. Conclusions There is limited evidence about the optimal strategies for monitoring and updating clinical practice guidelines. A restricted search is likely to be sufficient to monitor new evidence and assess the need to update, however, more information is needed about the timing and type of search. Only the exhaustive search strategy has been assessed for the update of CPGs. The development and evaluation of more efficient

  10. The hydrobioid freshwater gastropods (Caenogastropoda, Truncatelloidea) of Greece: new records, taxonomic re-assessments using DNA sequence data and an update of the IUCN Red List Categories.

    Science.gov (United States)

    Radea, Canella; Parmakelis, Aristeidis; Papadogiannis, Vassilis; Charou, Despoina; Triantis, Kostas A

    2013-01-01

    Hydrobioid freshwater gastropods were collected from mainland and insular Greece. Several threatened taxa, such as Graecoanatolica vegorriticola, Pseudamnicola negropontina, Pseudamnicola pieperi, Pseudobithynia eubooensis and Pseudoislamia balcanica, were recorded from new localities. Trichonia trichonica, which has been considered extinct from its type locality for the last twenty eight years, was re-discovered, whereas the presence of Daphniola exigua, G. vegorriticola, Marstoniopsis graeca, P. pieperi and Pseudobithynia trichonis in their type localities was verified. The taxonomic status of P. negropontina and the newly discovered populations of G. vegorriticola was elucidated using COI sequence data. The new data recorded during this survey indicate that the IUCN status of some Greek endemic hydrobioids needs to be updated.

  11. Stock Assessment Supplementary Information (SASINF)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — In the interest of efficiency, clarity and standardization of stock assessment materials, the stock assessment reports for the 2015 Groundfish update have been...

  12. A Training Program Using an Audience Response System to Calibrate Dental Faculty Members Assessing Student Clinical Competence.

    Science.gov (United States)

    Metz, Michael J; Metz, Cynthia J; Durski, Marcelo T; Aiken, Sean A; Mayfield, Theresa G; Lin, Wei-Shao

    2016-09-01

    The aim of this study was to assess the effectiveness of calibration training of departmental faculty and competency graders using an audience response system on operative dentistry concepts across 12 months. The training sessions were designed to further solidify the process and equilibration of clinical opinions among faculty members and provide a more calibrated grading assessment during patient care for student performance feedback. Four (quarterly) calibration sessions occurred over 12 months in 2015. The first session was considered the baseline (control value) for this study. Pre- and post-calibration interrater agreement was assessed. Additionally, a pre and post assessment with ten Likert-scale questions was used to measure students' perceptions of instructional consistency. The results showed that a statistically significant increase in conceptual knowledge scores occurred for both departmental faculty members and competency graders across each of the four sessions (one-factor ANOVA; paudience response system for departmental and competency graders was found to be effective in facilitating a discussion forum, calibrating clinical assessments, and improving student perceptions. The positive results from this study support the value of dental schools' introducing faculty development programs to ensure consistent instruction for assessing dental student competence.

  13. Liposuction devices: technology update

    Directory of Open Access Journals (Sweden)

    Shridharani SM

    2014-07-01

    Full Text Available Sachin M Shridharani,1 Justin M Broyles,2 Alan Matarasso11The Department of Plastic Surgery, Manhattan Eye, Ear and Throat Hospital, New York, NY, USA; 2The Department of Plastic Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, USAAbstract: Since its introduction by Illouz and others over 30 years ago, suction-assisted lipectomy/liposuction/lipoplasty has evolved tremendously and has developed into one of the most popular procedures in aesthetic plastic surgery. Liposuction is an effective procedure employed to treat localized adipose deposits in patients not suffering from generalized obesity. These accumulations of subcutaneous fat often occur in predictable distributions in both men and women. A cannula connected to a suction-generating source allows for small incisions to be strategically placed and large volumes of fat to be removed. This fat removal leads to improved harmonious balance of a patient's physique and improved body contour. Various surgical techniques are available and have evolved as technology has improved. Current technology for liposuction includes suction-assisted lipectomy, ultrasound-assisted, power-assisted, laser-assisted, and radiofrequency-assisted. The choice of technology and technique often depends on patient characteristics and surgeon preference. The objective of this review is to provide a thorough assessment of current technologies available to plastic surgeons performing liposuction.Keywords: laser, lipoplasty, mesotherapy, power-assisted, radiofrequency, ultrasound, water-assisted, coolsculpting

  14. [Bariatric surgery: an update].

    Science.gov (United States)

    Moreno Esteban, B; Zugasti Murillo, A

    2004-01-01

    The indication of bariatric surgery as therapeutic procedure for morbid obese patients requires the application of selection criteria which deal with the degree of obesity, associated complications and previous failure of conventional therapy. Alcohol or drug addiction and concomitant serious disease are contraindications for bariatric surgery. Before operation, a full assessment is needed to identify possible eating behaviour disturbances and associated comorbidity such as cardiovascular disease, sleep apnoea, metabolic and psychiatric alterations which might induce intra and postoperative complications. Surgical techniques can be classified as restrictive, malabsortive and mixed procedures. Gastroplasty and adjustable gastric banding are restrictive techniques, which are indicated in obese patients with body mass index less than 45 kg/m2. Mixed techniques are the most used procedures. They include gastric by-pass which causes a reduction of 60-70% of weight excess, biliopancreatic diversion and duodenal switch which can eliminate a 75% of body weight excess. Following bariatric surgery a dramatic improvement in associated comorbidity can be demonstrated, specially in what refers to diabetes, hypertension, dislipidaemia and apnoea. Postoperative mortality is around 1-2%. Peritonitis and venous thromboembolism are the most serious complications. Postoperative follow-up should be lifelong and requires a progressive nutrition planning and vitamin supplementation.

  15. Bevalac operations update

    Energy Technology Data Exchange (ETDEWEB)

    1991-02-01

    The Bevalac passed the recent Tiger Team assessment with flying colors, thanks to the unremitting effort of countless people over the last several months, pulling miles of cables, sending tons of valuable'' junk to salvage, painting, pushing brooms, writing operating procedures. It is time to look ahead now and plan for doing science again; however, it is not business as usual. The Bevalac survived, but not without changes. There are more procedures to be followed, safety appraisals to be made, training to be gone through. The primary goal is not just to get a task done, but to get it done in a safe manner according to code. If this means a delay in a run because enough time wasn't allotted for making a change in the setup, then the experiment will be delayed. Many of the obvious changes you will find the next time you come to work here are summarized in this newsletter. We will inform you of others as they are forthcoming. Also we will discuss these changes at our We Survived the Tigers, but{hor ellipsis}'' Users' Information Meeting at the Washington APS meeting. Details are inside this report.

  16. PACE Status Update

    Energy Technology Data Exchange (ETDEWEB)

    M., Zimring,; Hoffman, I.; Fuller, M.

    2010-08-11

    The Federal Housing Finance Agency (FHFA) regulates Fannie Mae, Freddie Mac, and the 12 Federal Home Loan Banks (the government-sponsored enterprises - GSEs). On July 6, 2010, FHFA and the Office of the Comptroller of the Currency (OCC) concluded that Property Assessed Clean Energy (PACE) programs 'present significant safety and soundness concerns' to the housing finance industry. This statement came after a year of discussions with state and federal agencies in which PACE, a novel mechanism for financing energy efficiency and renewable energy improvements, has gone from receiving support from the White House, canonization as one of Scientific American's 'World Changing Ideas' and legislative adoption in 24 states to questionable relevance, at least in the residential sector. Whether PACE resumes its expansion as an innovative tool for financing energy efficiency and clean generation depends on outcomes in each of the three branches of government - discussions on a PACE pilot phase among federal agencies, litigation in federal court, and legislation in Congress - all highly uncertain. This policy brief addresses the practical impacts of these possible outcomes on existing and emerging PACE programs across the United States and potential paths forward.

  17. The Evaluation of the Antimicobial Self-Assessment Toolkit for NHS Trusts

    OpenAIRE

    2013-01-01

    Introduction: The Antimicrobial Self-assessment Toolkit for Acute NHS Trusts (ASAT) was developed by a pharmacist reference group of an Advisory Non-Departmental Public Body on Antimicrobial Resistance and Healthcare Associated Infections (ARHAI). It was developed in conjunction with the Department of Health. The primary purpose of the ASAT is to identify and to measure the methods of implementation of antimicrobial stewardship programmes in acute NHS trusts. The face validity was previously...

  18. Updated Colombian Seismic Hazard Map

    Science.gov (United States)

    Eraso, J.; Arcila, M.; Romero, J.; Dimate, C.; Bermúdez, M. L.; Alvarado, C.

    2013-05-01

    possible to determinate environments and scenarios where the seismic hazard is a function of distance and magnitude and also the principal seismic sources that contribute to the seismic hazard at each site (dissagregation). This project was conducted by the Servicio Geológico Colombiano (Colombian Geological Survey) and the Universidad Nacional de Colombia (National University of Colombia), with the collaboration of national and foreign experts and the National System of Prevention and Attention of Disaster (SNPAD). It is important to stand out that this new seismic hazard map was used in the updated national building code (NSR-10). A new process is ongoing in order to improve and present the Seismic Hazard Map in terms of intensity. This require new knowledge in site effects, in both local and regional scales, checking the existing and develop new acceleration to intensity relationships, in order to obtain results more understandable and useful for a wider range of users, not only in the engineering field, but also all the risk assessment and management institutions, research and general community.

  19. Enhancing Prosecutorial Supervision of Community Correction through Departmental Interaction%部门联动,加强社区矫正检察监督

    Institute of Scientific and Technical Information of China (English)

    闵丰锦

    2015-01-01

    随着社区矫正制度的正式确立,检察机关的法律监督工作处于更加重要的地位。由于基层力量薄弱、立法有所不足、执行存在盲区等,社区矫正检察监督存在一定的理念落后、势单力薄现象。秉持保障人权的理念,通过检察机关的侦查监督部门、公诉部门、监所部门的合力联动,夯实社区矫正的基础,提出社区矫正的建议,监督社区矫正的执行,进一步做好社区矫正检察监督工作。%With the establishment of the community correction in China,the procuratorial organ plays a more important role in le-gal supervision. Due to the lack of law enforcement at the grass-roots level,the flaws of legislation and the dead zone in law en-forcement,several problems occur in the prosecutorial supervision of community correction,such as the lagging concept and in-capability. Based on the concept of protecting human rights,through the departmental interaction by the investigation supervision department,the public prosecution department and the prison supervision department of the procuratorial organ,the community correction can be largely enhanced,such as solidify the basis,offer the proposal and supervise the implementation.

  20. An Update on the KFIB Experiment

    Energy Technology Data Exchange (ETDEWEB)

    Youngblood, Gerald E.; Jones, Russell H.; Kowbel, W.; De Heij, Paul; Kohyama, Akira

    2001-06-30

    An updated sample test matrix for the KFIB experiment is presented. The pre-irradiation test results for all fiber and SiC/SiC composite materials included in the test matrix, recently presented at the 4th IEA Workshop on SiC/SiC for Fusion Structural Applications held in Frascati, Italy, October 12-13, 2000, are reviewed. The KFIB samples have been delivered for capsule loading. They are scheduled to be irradiated from May through October, 2001 to similar doses (2-4 dpa-SiC) in the ATR (Idaho Falls) at 300?C and the HFR (Petten) at 625 and 975?C. To assess irradiation enhanced creep (IEC) in SiC fibers, a bend stress relaxation module was added to the HFR sample matrix at each irradiation temperature.

  1. INHERITED NEUROPATHIES: CLINICAL OVERVIEW AND UPDATE

    Science.gov (United States)

    KLEIN, CHRISTOPHER J.; DUAN, XIAOHUI; SHY, MICHAEL E.

    2014-01-01

    Inherited neuropathy is a group of common neurologic disorders with heterogeneous clinical presentations and genetic causes. Detailed neuromuscular evaluations, including nerve conduction studies, laboratory testing, and histopathologic examination, can assist in identification of the inherited component beyond family history. Genetic testing increasingly enables definitive diagnosis of specific inherited neuropathies. Diagnosis, however, is often complex, and neurologic disability may have both genetic and acquired components in individual patients. The decision of which genetic test to order or whether to order genetic tests is often complicated, and the strategies to maximize the value of testing are evolving. Apart from rare inherited metabolic neuropathies, treatment approaches remain largely supportive. We provide a clinical update of the various types of inherited neuropathies, their differential diagnoses, and distinguishing clinical features (where available). A framework is provided for clinical evaluations, including the inheritance assessment, electrophysiologic examinations, and specific genetic tests. PMID:23801417

  2. Update of the SPS Impedance Model

    CERN Document Server

    Salvant, B; Zannini, C; Arduini, G; Berrig, O; Caspers, F; Grudiev, A; Métral, E; Rumolo, G; Shaposhnikova, E; Zotter, B; Migliorati, M; Spataro, B

    2010-01-01

    The beam coupling impedance of the CERN SPS is expected to be one of the limitations to an intensity upgrade of the LHC complex. In order to be able to reduce the SPS impedance, its main contributors need to be identified. An impedance model for the SPS has been gathered from theoretical calculations, electromagnetic simulations and bench measurements of single SPS elements. The current model accounts for the longitudinal and transverse impedance of the kickers, the horizontal and vertical electrostatic beam position monitors, the RF cavities and the 6.7 km beam pipe. In order to assess the validity of this model, macroparticle simulations of a bunch interacting with this updated SPS impedance model are compared to measurements performed with the SPS beam.

  3. Update on the management of dyslipidemia.

    Science.gov (United States)

    Irons, Brian K; Snella, Kathleen A; McCall, Kenneth; MacLaughlin, Eric J; Villarreal, Maumi

    2002-09-01

    The third edition of guidelines from the National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III [ATP III]) is discussed. The most recent classifications for low-density-lipoprotein (LDL) cholesterol, high-density-lipoprotein (HDL), total cholesterol, and triglycerides are provided. LDL cholesterol goals, cardiovascular risk assessment, therapeutic goals, and pharmacologic treatment options are discussed for both primary and secondary prevention of cardiovascular disease. In addition, the management of dyslipidemia in patients with diabetes and metobolic syndrome is addressed, and the differences between the old and new guidelines are highlighted. The ATP III guidelines may help health care professionals to better screen and categorize patients on the basis of their coronary heart disease (CHD) risk. The updated guidelines recommend more intensive lipid-lowering treatments for primary prevention in patients with two or more risk factors.

  4. Human teratogens: update 2010.

    Science.gov (United States)

    Holmes, Lewis B

    2011-01-01

    A wide variety of human teratogens have been identified. The characteristics of human teratogens can be used in the assessment of apparent "new" teratogens, when postulated. Information is available through online databases, such as TERIS and Reprotox, telephone-based counseling resources (e.g., Organization of Teratogen Information Systems [OTIS] and European Network Teratology Information Services [ENTIS]), reference books, annual meetings of the Teratology Society, and published articles. There are significant deficiencies in the information available: (1) lack of knowledge about the molecular and cellular basis for most teratogenic effects; (2) the inability to genetically identify more susceptible women before pregnancy; (3) little information is available on dermal and airborne exposures during pregnancy; and (4) most clinicians receive little, if any, training in the identification of or counseling for exposure to potential teratogens. There are many current dilemmas in counseling about exposures in pregnancy, including: (1) Is exposure to specific drugs, such as selected serotonin re-uptake inhibitors (SSRIs) and the inhibitors of tumor necrosis factor-alpha, teratogenic in the first trimester of pregnancy? (2) Are the increased risks of birth defects associated with assisted reproductive technology due, in part, to epigenetic effects? (3) What are the "safe" levels of exposure to the plasticizers phthalates during pregnancy? (4) How do we convince busy physicians, nurses, and pharmacists not to use the drug categories A, B, C, D, and X in counseling and to use more accurate sources? There is a need for a national advisory center for pregnancy registries to provide guidance when new registries are being developed.

  5. [Preoperative fasting guidelines: an update].

    Science.gov (United States)

    López Muñoz, A C; Busto Aguirreurreta, N; Tomás Braulio, J

    2015-03-01

    Anesthesiology societies have issued various guidelines on preoperative fasting since 1990, not only to decrease the incidence of lung aspiration and anesthetic morbidity, but also to increase patient comfort prior to anesthesia. Some of these societies have been updating their guidelines, as such that, since 2010, we now have 2 evidence-based preoperative fasting guidelines available. In this article, an attempt is made to review these updated guidelines, as well as the current instructions for more controversial patients such as infants, the obese, and a particular type of ophthalmic surgery. Copyright © 2014 Sociedad Española de Anestesiología, Reanimación y Terapéutica del Dolor. Publicado por Elsevier España, S.L.U. All rights reserved.

  6. Lumbar discography: an update.

    Science.gov (United States)

    Anderson, Mark W

    2004-01-01

    and then come back to reinject more contrast into the disk in question. As radiologists, we tend to focus on the technical aspects of a procedure and the anatomic/morphologic information it provides. However, it cannot be emphasized enough that when performing lumbar discography, the assessment of the patient's pain response during the injection is the most important component of the procedure, and requires not only technical skills, but an understanding of how best to avoid some of the pitfalls that can lead to inaccurate results.

  7. Update on Allergy Immunotherapy

    Directory of Open Access Journals (Sweden)

    Davidson William

    2005-12-01

    Full Text Available Abstract This article summarizes and provides commentary regarding guidelines on the administration of immunotherapy (IT for allergic airway disease. Recent investigations have provided important insights into the immunologic mechanism of IT and the prominent role of interleukin-10-producing regulatory T lymphocytes. The most important aspect of successful IT is the administration of an appropriate dose of an extract containing a sufficient concentration of the relevant allergen. This is largely possible now only with standardized extracts. When the major allergen content of successful IT extracts was quantified, efficacy was demonstrated across a surprisingly narrow concentration range (approximately 5-24 μg per injection, irrespective of the extract. This presumably reflects the concentration of an antigen that drives an immune response toward tolerance. It may be predicted that as major allergen content is quantified in currently nonstandardized extracts, effective IT will also be achieved by administering a dose in this range, in contrast to current practices involving fairly arbitrary dosing decisions. With the availability of nonsedating antihistamines, intranasal corticosteroids, and the leukotriene modifiers, inadequate pharmacologic response or intolerable side effects are less commonly the major indications for starting IT for allergic rhinitis (AR. However, with the recognition that a relatively short course (3-5 years of IT can provide long-term immunomodulation and clinical benefit, a desire to avoid long-term pharmacotherapy and the associated high costs may be the primary indication for IT in AR cases. While evidence overwhelmingly supports the beneficial influences of IT in asthma cases, the positioning of IT for this disorder is not established. The observed prevention of asthma in children who have AR is intriguing, but further studies are required to assess the extent to which the prevalence and severity of chronic asthma

  8. MEMS Stirling Cooler Development Update

    Science.gov (United States)

    Moran, Matthew E.; Wesolek, Danielle

    2003-01-01

    This presentation provides an update on the effort to build and test a prototype unit of the patented MEMS Stirling cooler concept. A micro-scale regenerator has been fabricated by Polar Thermal Technologies and is currently being integrated into a Stirling cycle simulator at Johns Hopkins University Applied Physics Laboratory. A discussion of the analysis, design, assembly, and test plans for the prototype will be presented.

  9. Biofeedback and Performance: An Update

    Science.gov (United States)

    1984-12-01

    non- biofeedback meditation procedure; a single control was a group untrained in relaxation. It is not clear what instructions if any were given to...and meditation in the treatment of generalized anxiety. Proceedings of the 14th Annual Meeting of the Biofeedback Society of America, 187-189...A Technical Report 658 N BIOFEEDBACK AND PERFORMANCE: Cq AN UPDATE In George H. Lawrence BASIC RESEARCH 6 U.I.S. Army _ Research Institute for the

  10. An update on percutaneous nephrolithotomy

    DEFF Research Database (Denmark)

    Tefekli, A; Cordeiro, E; de la Rosette, J J M C H

    2013-01-01

    Since its introduction in late 1970's, percutaneous nephrolithotomy (PNL) has undergone an evolution in both equipment and technique. This evolution still continues today in the era of minimally invasive treatment options, and is evidenced by the numerous publications. PNL is generally advantageo...... patients managed with PNL worldwide and analyzed the data in detail, producing more than 25 scientific papers. And this update focuses on the lessons learned from the CROES PCNL Global Study....

  11. Updated SAO OMI formaldehyde retrieval

    Directory of Open Access Journals (Sweden)

    G. González Abad

    2014-01-01

    Full Text Available We present and discuss the Smithsonian Astrophysical Observatory (SAO formaldehyde (H2CO retrieval algorithm for the Ozone Monitoring Instrument (OMI which is the operational retrieval for NASA OMI H2CO. The version of the algorithm described here includes relevant changes with respect to the operational one, including differences in the reference spectra for H2CO, the fit of O2-O2 collisional complex, updates in the high resolution solar reference spectrum, the use of a model reference sector over the remote Pacific Ocean to normalize the retrievals, an updated Air Mass Factor (AMF calculation scheme, and the inclusion of scattering weights and vertical H2CO profile in the level 2 products. The theoretical basis of the retrieval is discussed in detail. Typical values for retrieved vertical columns are between 4 × 1015 and 4 × 1016 molecules cm−2 with typical fitting uncertainties ranging between 40% and 100%. In high concentration regions the errors are usually reduced to 30%. The detection limit is estimated at 3 × 1015 molecules cm−2. These updated retrievals are compared with previous ones.

  12. Update of CERN exchange network

    CERN Multimedia

    2003-01-01

    An update of the CERN exchange network will be done next April. Disturbances or even interruptions of telephony services may occur from 4th to 24th April during evenings from 18:30 to 00:00 but will not exceed more than 4 consecutive hours (see tentative planning below). In addition, the voice messaging system will be shut down on March, 26th April from 18:00 to 00:00. Calls supposed to be routed to the voice messaging system will not be possible during the shutdown. CERN divisions are invited to avoid any change requests (set-ups, move or removals) of telephones and fax machines from 4th to 25th April. Everything will be done to minimize potential inconveniences which may occur during this update. There will be no loss of telephone functionalities. CERN GSM portable phones won't be affected by this change. Should you need more details, please send us your questions by email to Standard.Telephone@cern.ch. Date Change type Affected areas March 26 Update of the voice messaging system All CERN sites April...

  13. Research on Topographic Map Updating

    Directory of Open Access Journals (Sweden)

    Ivana Javorović

    2013-04-01

    Full Text Available The investigation of interpretability of panchromatic satellite image IRS-1C integrated with multispectral Landsat TM image with the purpose of updating the topographic map sheet at the scale of 1:25 000 has been described. The geocoding of source map was based on trigonometric points of the map sheet. Satellite images were geocoded using control points selected from the map. The contents of map have been vectorized and topographic database designed. The digital image processing improved the interpretability of images. Then, the vectorization of new contents was made. The change detection of the forest and water area was defined by using unsupervised classification of spatial and spectral merged images. Verification of the results was made using corresponding aerial photographs. Although this methodology could not insure the complete updating of topographic map at the scale of 1:25 000, the database has been updated with huge amount of data. Erdas Imagine 8.3. software was used. 

  14. Preeclampsia: an update.

    Science.gov (United States)

    Lambert, G; Brichant, J F; Hartstein, G; Bonhomme, V; Dewandre, P Y

    2014-01-01

    Preeclampsia was formerly defined as a multisystemic disorder characterized by new onset of hypertension (i.e. systolic blood pressure (SBP) ≥ 140 mmHg and/or diastolic blood pressure (DBP) ≥ 90 mmHg) and proteinuria (> 300 mg/24 h) arising after 20 weeks of gestation in a previously normotensive woman. Recently, the American College of Obstetricians and Gynecologists has stated that proteinuria is no longer required for the diagnosis of preeclampsia. This complication of pregnancy remains a leading cause of maternal morbidity and mortality. Clinical signs appear in the second half of pregnancy, but initial pathogenic mechanisms arise much earlier. The cytotrophoblast fails to remodel spiral arteries, leading to hypoperfusion and ischemia of the placenta. The fetal consequence is growth restriction. On the maternal side, the ischemic placenta releases factors that provoke a generalized maternal endothelial dysfunction. The endothelial dysfunction is in turn responsible for the symptoms and complications of preeclampsia. These include hypertension, proteinuria, renal impairment, thrombocytopenia, epigastric pain, liver dysfunction, hemolysis-elevated liver enzymes-low platelet count (HELLP) syndrome, visual disturbances, headache, and seizures. Despite a better understanding of preeclampsia pathophysiology and maternal hemodynamic alterations during preeclampsia, the only curative treatment remains placenta and fetus delivery. At the time of diagnosis, the initial objective is the assessment of disease severity. Severe hypertension (SBP ≥ 160 mm Hg and/or DBP ≥ 110 mmHg), thrombocytopenia preeclampsia, and relies on antihypertensive medications and magnesium sulfate. Medical treatment does not alter the course of the disease, but aims at preventing the occurrence of intracranial hemorrhages and seizures. The decision of terminating pregnancy and perform delivery is based on gestational age, maternal and fetal conditions, and severity of preeclampsia

  15. NEWS: Post-16 update

    Science.gov (United States)

    Campbell, Peter

    2000-07-01

    post16.gif As a teacher of physics it is very easy to become preoccupied with particulars of courses, or topics or even single concepts. Concerned with imminent student audiences and desired learning outcomes, the daily challenge is to summon satisfactory teaching approaches and resources for the job at hand. For the conscientious teacher, assessment outcomes may too often seem a judgment on our own efforts rather than those of our students. From time to time we may step back and think bigger, for example while planning a recruitment event, or while away from work on holiday. We may be successful locally. But why, at a time when books and television documentaries popularizing science have a large following, has physics education been facing declining numbers? Many recognize that physics has an essential contribution to make to the training of science or engineering specialists, but we know that it is also important for the skilled worker, the informed citizen and, in fact, for anyone trying to make sense of the world. So what are the best ways forward for post-16 physics? To make any impact on the bigger picture requires organization, thinking and meeting time among people in diverse roles: teachers and curriculum managers; university lecturers; employers and professional bodies; unitary awarding bodies; regulatory and funding agencies; and even Government. For the past few years, the Institute of Physics post-16 Initiative has created an unrivalled opportunity to address the wider issues. Its Shaping the Future booklets series was designed to stimulate informed discussion and debate, by providing background information and analysis. Taken together, the booklets should help all those concerned with physics education to understand where we are now, and why. Literally dozens of people have contributed to a review and analysis of physics education. Each booklet is a 48-page smorgasbord in A4 landscape format, containing many examples of good practice, basic but

  16. Satellite image based methods for fuels maps updating

    Science.gov (United States)

    Alonso-Benito, Alfonso; Hernandez-Leal, Pedro A.; Arbelo, Manuel; Gonzalez-Calvo, Alejandro; Moreno-Ruiz, Jose A.; Garcia-Lazaro, Jose R.

    2016-10-01

    Regular updating of fuels maps is important for forest fire management. Nevertheless complex and time consuming field work is usually necessary for this purpose, which prevents a more frequent update. That is why the assessment of the usefulness of satellite data and the development of remote sensing techniques that enable the automatic updating of these maps, is of vital interest. In this work, we have tested the use of the spectral bands of OLI (Operational Land Imager) sensor on board Landsat 8 satellite, for updating the fuels map of El Hierro Island (Spain). From previously digitized map, a set of 200 reference plots for different fuel types was created. A 50% of the plots were randomly used as a training set and the rest were considered for validation. Six supervised and 2 unsupervised classification methods were applied, considering two levels of detail. A first level with only 5 classes (Meadow, Brushwood, Undergrowth canopy cover >50%, Undergrowth canopy cover <15%, and Xeric formations), and the second one containing 19 fuel types. The level 1 classification methods yielded an overall accuracy ranging from 44% for Parellelepided to an 84% for Maximun Likelihood. Meanwhile, level 2 results showed at best, an unacceptable overall accuracy of 34%, which prevents the use of this data for such a detailed characterization. Anyway it has been demonstrated that in some conditions, images of medium spatial resolution, like Landsat 8-OLI, could be a valid tool for an automatic upgrade of fuels maps, minimizing costs and complementing traditional methodologies.

  17. Reliability and Maintainability (R&M) Engineering Update

    Science.gov (United States)

    2012-05-22

    training Workforce assessment Schedule approach driven by issuance of DTM 11-003 Guidance. R&M Engineering May 2012 Page 12 Distribution...PURPOSE • Provide an update of DoD R&M Engineering Activities and Initiatives OUTLINE • Policy • Guidance and Standardization • Workforce ...achievement during IOTE and report this to the MDA at MS C • Establishes specific reliability monitoring and reporting throughout the acquisition

  18. Experimental model updating using frequency response functions

    Science.gov (United States)

    Hong, Yu; Liu, Xi; Dong, Xinjun; Wang, Yang; Pu, Qianhui

    2016-04-01

    In order to obtain a finite element (FE) model that can more accurately describe structural behaviors, experimental data measured from the actual structure can be used to update the FE model. The process is known as FE model updating. In this paper, a frequency response function (FRF)-based model updating approach is presented. The approach attempts to minimize the difference between analytical and experimental FRFs, while the experimental FRFs are calculated using simultaneously measured dynamic excitation and corresponding structural responses. In this study, the FRF-based model updating method is validated through laboratory experiments on a four-story shear-frame structure. To obtain the experimental FRFs, shake table tests and impact hammer tests are performed. The FRF-based model updating method is shown to successfully update the stiffness, mass and damping parameters of the four-story structure, so that the analytical and experimental FRFs match well with each other.

  19. Updating systematic reviews: an international survey.

    Directory of Open Access Journals (Sweden)

    Chantelle Garritty

    Full Text Available BACKGROUND: Systematic reviews (SRs should be up to date to maintain their importance in informing healthcare policy and practice. However, little guidance is available about when and how to update SRs. Moreover, the updating policies and practices of organizations that commission or produce SRs are unclear. METHODOLOGY/PRINCIPAL FINDINGS: The objective was to describe the updating practices and policies of agencies that sponsor or conduct SRs. An Internet-based survey was administered to a purposive non-random sample of 195 healthcare organizations within the international SR community. Survey results were analyzed using descriptive statistics. The completed response rate was 58% (n = 114 from across 26 countries with 70% (75/107 of participants identified as producers of SRs. Among responders, 79% (84/107 characterized the importance of updating as high or very-high and 57% (60/106 of organizations reported to have a formal policy for updating. However, only 29% (35/106 of organizations made reference to a written policy document. Several groups (62/105; 59% reported updating practices as irregular, and over half (53/103 of organizational respondents estimated that more than 50% of their respective SRs were likely out of date. Authors of the original SR (42/106; 40% were most often deemed responsible for ensuring SRs were current. Barriers to updating included resource constraints, reviewer motivation, lack of academic credit, and limited publishing formats. Most respondents (70/100; 70% indicated that they supported centralization of updating efforts across institutions or agencies. Furthermore, 84% (83/99 of respondents indicated they favoured the development of a central registry of SRs, analogous to efforts within the clinical trials community. CONCLUSIONS/SIGNIFICANCE: Most organizations that sponsor and/or carry out SRs consider updating important. Despite this recognition, updating practices are not regular, and many organizations lack

  20. Airborne Network Optimization with Dynamic Network Update

    Science.gov (United States)

    2015-03-26

    AIRBORNE NETWORK OPTIMIZATION WITH DYNAMIC NETWORK UPDATE THESIS Bradly S. Paul, Capt, USAF AFIT-ENG-MS-15-M-030 DEPARTMENT OF THE AIR FORCE AIR...to copyright protection in the United States. AFIT-ENG-MS-15-M-030 AIRBORNE NETWORK OPTIMIZATION WITH DYNAMIC NETWORK UPDATE THESIS Presented to the...NETWORK OPTIMIZATION WITH DYNAMIC NETWORK UPDATE Bradly S. Paul, B.S.C.P. Capt, USAF Committee Membership: Maj Thomas E. Dube Chair Dr. Kenneth M. Hopkinson

  1. Updates

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    Chinese Academy of Social Sciences released the "China Industry Competitiveness Report (2012) NO.2", Guo Chaoxian, deputy director of Industrial Organization Office of Academy of Social Sciences Institute of Industrial Economics, said that textile and garmentindustry was China's most competitive industries, product market share ranked the second in the world, while productivity was 14 times of the United States. Guo Chaoxian noted that China's textile and garment industry was the most competitive national industry, no matter in terms of international market share, trade competitiveness index, the real index of comparative advantage, all were regarded as the strongest in the world. China's textile and garment industry's market share came in the second in the world, six times of Italy, seven times of Germany and twelve times of the United States.

  2. Updates

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    China's middle and low textile export situation remains grim. India's ban on cotton exports is to improve the competitiveness of the terminal textiles in the international market. In recent years, India has become the opponent of the Chinese textile exports in the international market, especially in the low-end textiles. India relies on the advantages of raw material and labor cost to continue to erode China's international market share. Though the overall technical level of the domestic textile industry and transport conditions are not as good as China, its current price advantage pose a large threat to China's low-end textile and garment exports.

  3. Updates

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    2011 Chinese online shopping industry continues the momentum of rapid development in 2010, gradually narrowing the gap of the online shopping environment in the region, online shopping growth in some of the second and third tier provinces performed outstandingly. According to the iResearch ECPlus monitoring data,

  4. An update on chemistry analyzers.

    Science.gov (United States)

    Vap, L M; Mitzner, B

    1996-09-01

    This update of six chemistry analyzers available to the clinician discusses several points that should be considered prior to the purchase of equipment. General topics include how to best match an instrument to clinic needs and the indirect costs associated with instrument operation. Quality assurance recommendations are discussed and common terms are defined. Specific instrument features, principles of operation, performance, and costs are presented. The information provided offers potential purchasers an objective approach to the evaluation of a chemistry analyzer for the veterinary clinic.

  5. Update on biosimilars in rheumatology.

    Science.gov (United States)

    Rischin, Adam; Östör, Andrew J K

    2017-04-01

    Biologic agents have become indispensable in the management of autoimmune disease particularly rheumatological conditions. The lives of countless individuals have been improved following treatment with these drugs. Unfortunately, their cost prohibits more widespread use around the globe. This critical issue has been addressed by the introduction of biosimilars into the market. These therapies have been developed to resemble the originator molecule as closely as possible and to increase competition in the therapy area thus allowing costs to be reduced. Our review is intended to offer an update on biosimilars including logistic considerations on their introduction into routine practice.

  6. Primary Anorectal Melanoma: An Update

    Directory of Open Access Journals (Sweden)

    P Carcoforo, M.T Raiji, G.M Palini, M Pedriali, U Maestroni, G Soliani, A Detroia, M.V Zanzi, A.L Manna, J.G Crompton, R.C Langan, A Stojadinovic, I Avital

    2012-01-01

    Full Text Available The anorectum is a rare anatomic location for primary melanoma. Mucosal melanoma is a distinct biological and clinical entity from the more common cutaneous melanoma. It portrays worse prognosis than cutaneous melanoma, with distant metastases being the overwhelming cause of morbidity and mortality. Surgery is the treatment of choice, but significant controversy exists over the extent of surgical resection. We present an update on the state of the art of anorectal mucosal melanoma. To illustrate the multimodality approach to anorectal melanoma, we present a typical patient.

  7. Communication technology update and fundamentals

    CERN Document Server

    Grant, August E

    2014-01-01

    A classic now in its 14th edition, Communication Technology Update and Fundamentals is the single best resource for students and professionals looking to brush up on how these technologies have developed, grown, and converged, as well as what's in store for the future. It begins by developing the communication technology framework-the history, ecosystem, and structure-then delves into each type of technology, including everything from mass media, to computers and consumer electronics, to networking technologies. Each chapter is written by faculty and industry experts who p

  8. Cushing syndrome: update on testing.

    Science.gov (United States)

    Raff, Hershel

    2015-03-01

    Endogenous hypercortisolism (Cushing syndrome) is one of the most enigmatic diseases in clinical medicine. The diagnosis and differential diagnosis of Cushing syndrome depend on proper laboratory evaluation. In this review, an update is provided on selected critical issues in the diagnosis and differential diagnosis of Cushing syndrome: the use of late-night salivary cortisol in initial diagnosis and for postoperative surveillance, and the use of prolactin measurement to improve the performance of inferior petrosal sinus sampling to distinguish Cushing disease from ectopic adrenocorticotropic hormone (ACTH) syndrome during differential diagnosis of ACTH-dependent Cushing syndrome. Copyright © 2015 Elsevier Inc. All rights reserved.

  9. Nordic MCL2 trial update

    DEFF Research Database (Denmark)

    Geisler, Christian H; Kolstad, Arne; Laurell, Anna

    2012-01-01

    Mantle cell lymphoma (MCL) is a heterogenic non-Hodgkin lymphoma entity, with a median survival of about 5 years. In 2008 we reported the early - based on the median observation time of 4 years - results of the Nordic Lymphoma Group MCL2 study of frontline intensive induction immunochemotherapy...... and autologous stem cell transplantation (ASCT), with more than 60% event-free survival at 5 years, and no subsequent relapses reported. Here we present an update after a median observation time of 6·5 years. The overall results are still excellent, with median overall survival and response duration longer than...

  10. 美国最新体育教师教育专业标准评析及启示%Assessment and analysis of updated American professional standard for physical education teachers and its enlightenment

    Institute of Scientific and Technical Information of China (English)

    姜志明; 王涛

    2015-01-01

    最新《体育师范专业本科和硕士标准》是美国NCATE协会制定的高校师范专业体育教师培养计划与标准的指导性文件。作为体育教师职前培养计划的评价和认证标准,《体育师范专业本科和硕士标准》的内容和架构与美国《学校体育国家标准》高度衔接,目标指向为培养高水平和质量的中小学体育教师。研究分析最新《体育师范专业本科和硕士标准》对推动我国体育教师教育标准的研究和制定有重要的启示。%The updated Physical Education Major Undergraduate and Graduate Standard is a develop-ment plan for college physical education teacher preparation and a standard guideline approved by A-merican National Council for Accreditation of Teacher Education( NCATE). As the evaluation and accreditation standard for professional physical education teachers,the structure and framework of the Standard are highly in consistent with the American National Standard for Physical Education, targeted at the development of primary and secondary school physical education teachers with high quality. The analysis of the Standard has important enlightenment for the formulation of physical ed-ucation teacher education standard in China.

  11. Model Updating Nonlinear System Identification Toolbox Project

    Data.gov (United States)

    National Aeronautics and Space Administration — ZONA Technology (ZONA) proposes to develop an enhanced model updating nonlinear system identification (MUNSID) methodology that utilizes flight data with...

  12. Update and revision of WHO air quality guidelines for Europe

    Energy Technology Data Exchange (ETDEWEB)

    Younes, M. [WHO European Centre for Environment and Health, Bilthoven (Netherlands). Bilthoven Div.

    1995-12-31

    The WHO Air Quality Guidelines for Europe (AQG), published in 1987, have provided a uniform basis for the development of strategies for the control of air pollution, and have contributed to the maintenance and improvement of public health in several countries. The aim of the guidelines is to provide a basis for protecting public health from adverse effects of air pollutants, and for eliminating or reducing to a minimum, those contaminants that are known or likely to be hazardous to human health and wellbeing. Since the publication of the first edition of the AQG, new scientific data in the fields of air pollution toxicology and epidemiology have accumulated and new developments in risk assessment methodologies have taken place, requiring updating and/or revision of the existing guidelines. This fact was recognized during the preparation of the initial work plan of the European Centre for Environment and Health, and it was recommended that the Centre undertake any necessary amendments and extensions to the Air Quality Guidelines. The updating procedure is being carried out in cooperation with the International Programme on Chemical Safety (IPCS) and the Commission of the European Communities (CEC) and will be implemented through working group meetings which require the preparation of working documents on specific air pollutants or mixtures and a final consultation to discuss the updated document.It was initiated by a Planning Meeting which was organized in January 1993. The purpose of the planning meeting was to set the framework for the updating and revision process, in particular to discuss the scope and purpose, the contents and the format of the revised AQG publication, to define the details of and the time schedule for the updating process and to identify the working groups needed and their way of operation. (author)

  13. Strategic Communication: A Departmental Transformation

    Science.gov (United States)

    2010-03-24

    Representatives Adam Smith and Mac Thornberry echoed this view in early March 2010 when they invited other members of the U.S. House of Representatives to...jfq_pages/ editions/i55/1.pdf (accessed January 15, 2010). 5 Ibid. 21 6 U.S. Representatives Adam Smith and Mac Thornberry, “Join the new Strategic

  14. Government Documents Departmental Operations Guide.

    Science.gov (United States)

    Wilson, John S.; And Others

    This manual for the operation and maintenance of the Government Documents Department at Baylor University's Moody Memorial Library is divided into 13 topical sections. The guide opens with the collection development policy statement, which covers the general collection, the maps division, and weeding government documents. Technical processing…

  15. High-speed AMB machining spindle model updating and model validation

    Science.gov (United States)

    Wroblewski, Adam C.; Sawicki, Jerzy T.; Pesch, Alexander H.

    2011-04-01

    High-Speed Machining (HSM) spindles equipped with Active Magnetic Bearings (AMBs) have been envisioned to be capable of automated self-identification and self-optimization in efforts to accurately calculate parameters for stable high-speed machining operation. With this in mind, this work presents rotor model development accompanied by automated model-updating methodology followed by updated model validation. The model updating methodology is developed to address the dynamic inaccuracies of the nominal open-loop plant model when compared with experimental open-loop transfer function data obtained by the built in AMB sensors. The nominal open-loop model is altered by utilizing an unconstrained optimization algorithm to adjust only parameters that are a result of engineering assumptions and simplifications, in this case Young's modulus of selected finite elements. Minimizing the error of both resonance and anti-resonance frequencies simultaneously (between model and experimental data) takes into account rotor natural frequencies and mode shape information. To verify the predictive ability of the updated rotor model, its performance is assessed at the tool location which is independent of the experimental transfer function data used in model updating procedures. Verification of the updated model is carried out with complementary temporal and spatial response comparisons substantiating that the updating methodology is effective for derivation of open-loop models for predictive use.

  16. U.S. Department of Energy, Office of Legacy Management Program Update, April-June 2009

    Energy Technology Data Exchange (ETDEWEB)

    None

    2009-04-01

    Welcome to the April-June 2009 issue of the U.S. Department of Energy (DOE) Office of Legacy Management (LM) Program Update. This publication is designed to provide a status of activities within LM. The Legacy Management goals are: (1) Protect human health and the environment through effective and efficient long-term surveillance and maintenance - This goal highlights DOE's responsibility to ensure long-term protection of people, the environment, and the integrity of engineered remedies and monitoring systems. (2) Preserve, protect, and make accessible legacy records and information - This goal recognizes LM's commitment to successfully manage records, information, and archives of legacy sites under its authority. (3) Support an effective and efficient work force structured to accomplish Departmental missions and assure continuity of contractor worker pension and medical benefits - This goal recognizes DOE's commitment to its contracted work force and the consistent management of pension and health benefits. As sites continue to close, DOE faces the challenges of managing pension plan and health benefits liability. (4) Manage legacy land and assets, emphasizing protective real and personal property reuse and disposition - This goal recognizes a DOE need for local collaborative management of legacy assets, including coordinating land use planning, personal property disposition to community reuse organizations, and protecting heritage resources (natural, cultural, and historical). (5) Improve program effectiveness through sound management - This goal recognizes that LM's goals cannot be attained efficiently unless the federal and contractor work force is motivated to meet requirements and work toward continuous performance improvement.

  17. [The scope of expert competence for the evaluation of non-compliance with the requirements of the departmental normative legal acts in the course of forensic medical panel examinations concerning "medical practice" in the criminal legal procedures].

    Science.gov (United States)

    Kovalev, A V; Pletianova, I V; Fetisov, V A

    2014-01-01

    This article is devoted to the analysis of the problem of expert competence for the evaluation of non-compliance with the requirements of the departmental normative legal acts in the course of forensic medical panel examinations concerning "medical practice" in the criminal legal procedures. The approaches to the solution of his problem are exemplified by forensic medical expertise of selected cases from obstetric and gynecological practice. It is demonstrated that investigations into non-compliance events arising in the work of medical facilities must include the analysis of the departmental normative legal acts that govern the organizational and diagnostic processes. These documents should be regarded as pertaining to an additional direct object and considered to be one of the constituent elements of.the offence to be identified during forensic medical expertise. Such documents are very specific in terms of their content and can not be properly interpreted by independent specialists possessing juristic knowledge alone. Therefore, the expert judgments concerning these issues must include well-reasoned arguments and solidly established evidence of normative legal character.

  18. Environmental Development Plan for Transportation Energy Conservation. FY 79 update

    Energy Technology Data Exchange (ETDEWEB)

    Singh, M. K.; Bernard, III, M. J.

    1978-12-15

    This is the first annual update of the Environment Development Plan (EDP) for the DOE Division of Transportation Energy Conservation program. It identifies the ecosystem, resource, physical environment, health, safety, and socioeconomic concerns associated with the division's transportation programs. These programs include the research, development, demonstration and assessment (RDD and A) of seventeen transportation technologies and several strategy and policy development and implementation projects. The transportation technologies projects deal with highway transport including electric vehicles, marine transport and pipeline transport. This EDP presents a research and assessment plan for resolving any potentially adverse environmental concerns stemming from these programs.

  19. Review of SKB's interim report of SR-Can: SKI's and SSI's evaluation of SKB's up-dated methodology for safety assessment

    Energy Technology Data Exchange (ETDEWEB)

    Dverstorp, Bjoern; Moberg, Leif; Wiebert, Anders; Xu Shulan [Swedish Radiation Protection Authority, Stockholm (Sweden); Stroemberg, Bo; Kautsky, Fritz; Lilja, Christina; Simic, Eva; Sundstroem, Benny; Toverud, Oeivind [Swedish Nuclear Power Inspectorate, Stockholm (Sweden)

    2005-07-01

    This report presents the findings of a review of the Swedish Nuclear Fuel and Waste Management Co.'s (SKB) interim report of the safety assessment SR-Can (SKB TR 04-11), conducted by the Swedish Radiation Protection Authority (SSI) and the Swedish Nuclear Power Inspectorate (SKI). SKB's interim report describes and exemplifies the safety assessment methodology that SKB plans to use in the oncoming licence applications for an encapsulation plant and a final repository for spent nuclear fuel. The authorities' review takes into account the findings of an international peer review of SKB's interim report. The authorities conclude that SKB has improved its safety assessment methodology in several aspects compared to earlier safety reports. Among other things the authorities commend SKB for giving a comprehensive account of relevant regulations and guidance, and for the systematic approach to identification and documentation of features, events and processes that need to be considered in the safety assessment. However, the authorities also conclude that important parts of SKB's method need to be further developed before they are mature enough to be used as a basis for a license application. The authorities' overall assessment is summarised in chapter 8 of this report.

  20. [Guidelines for specialized nutritional and metabolic support in the critically-ill patient. Update. Consensus of the Spanish Society of Intensive Care Medicine and Coronary Units-Spanish Society of Parenteral and Enteral Nutrition (SEMICYUC-SENPE): nutritional assessment].

    Science.gov (United States)

    Ruiz-Santana, S; Arboleda Sánchez, J A; Abilés, J

    2011-11-01

    Current parameters to assess nutritional status in critically-ill patients are useful to evaluate nutritional status prior to admission to the intensive care unit. However, these parameters are of little utility once the patient's nutritional status has been altered by the acute process and its treatment. Changes in water distribution affect anthropometric variables and biochemical biomarkers, which in turn are affected by synthesis and degradation processes. Increased plasma levels of prealbumin and retinol -proteins with a short half-life- can indicate adequate response to nutritional support, while reduced levels of these proteins indicate further metabolic stress. The parameters used in functional assessment, such as those employed to assess muscular or immune function, are often altered by drugs or the presence of infection or polyneuropathy. However, some parameters can be used to monitor metabolic response and refeeding or can aid prognostic evaluation.

  1. Efficient compensation handling via subjective updates

    NARCIS (Netherlands)

    J. Dedeić (Jovana); J. Pantović (Jovanka); J.A. Pérez Parra (Jorge)

    2017-01-01

    textabstractProgramming abstractions for compensation handling and dynamic update are crucial in specifying reliable interacting systems, such as Collective Adaptive Systems (CAS). Compensations and updates both specify how a system reacts in response to exceptional events. Prior work showed that

  2. 76 FR 22618 - Product List Update

    Science.gov (United States)

    2011-04-22

    ... From the Federal Register Online via the Government Publishing Office ] POSTAL REGULATORY COMMISSION 39 CFR Part 3020 Product List Update AGENCY: Postal Regulatory Commission. ACTION: Final rule. SUMMARY: The Commission is updating the postal product lists. This action reflects the disposition of...

  3. Non-Linear Approximation of Bayesian Update

    KAUST Repository

    Litvinenko, Alexander

    2016-06-23

    We develop a non-linear approximation of expensive Bayesian formula. This non-linear approximation is applied directly to Polynomial Chaos Coefficients. In this way, we avoid Monte Carlo sampling and sampling error. We can show that the famous Kalman Update formula is a particular case of this update.

  4. 10 CFR 26.57 - Authorization update.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Authorization update. 26.57 Section 26.57 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Granting and Maintaining Authorization § 26.57 Authorization update. (a) Before granting authorization to an individual whose authorization has been interrupted...

  5. 34 CFR 668.55 - Updating information.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false Updating information. 668.55 Section 668.55 Education... Information § 668.55 Updating information. (a)(1) Unless the provisions of paragraph (a)(2) or (a)(3) of this... applicant to verify the information contained in his or her application for assistance in an award year...

  6. Census in Schools Educator Update, March 2009

    Science.gov (United States)

    US Census Bureau, 2009

    2009-01-01

    The "Census in Schools Educator Update" is sent to educators and educational organizations periodically to keep them informed about current and upcoming census data and to provide ideas about how to use data in the classroom. This issue of the "Census in Schools Educator Update" newsletter focuses on the following topics: (1)…

  7. Better Plants Progress Update Fall 2013

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2013-09-23

    This Progress Update summarizes the significant energy saving achievements and cumulative cost savings made by these industry leaders from 2010-2012. The update also shares the plans and priorities over the next year for the Better Plants Program to continue to advance energy efficiency in the industrial sector.

  8. Situation Update: Summary of Weekly FluView

    Science.gov (United States)

    ... Seasonal Avian Swine/Variant Pandemic Other Get Email Updates To receive email updates about this page, enter ... Submit What's this? Submit Button Past Newsletters Situation Update: Summary of Weekly FluView Report Language: English Españ ...

  9. Reliability analysis and updating of deteriorating systems with subset simulation

    DEFF Research Database (Denmark)

    Schneider, Ronald; Thöns, Sebastian; Straub, Daniel

    2017-01-01

    Bayesian updating of the system deterioration model. The updated system reliability is then obtained through coupling the updated deterioration model with a probabilistic structural model. The underlying high-dimensional structural reliability problems are solved using subset simulation, which...

  10. Dynamic finite element model updating of prestressed concrete continuous box-girder bridge

    Institute of Scientific and Technical Information of China (English)

    Lin Xiankun; Zhang Lingmi; Guo Qintao; Zhang Yufeng

    2009-01-01

    The dynamic finite element model (FEM) of a prestressed concrete continuous box-girder bridge, called the Tongyang Canal Bridge, is built and updated based on the results of ambient vibration testing (AVT) using a real-coded accelerating genetic algorithm (RAGA). The objective functions are defined based on natural frequency and modal assurance criterion (MAC) metrics to evaluate the updated FEM. Two objective functions are defined to fully account for the relative errors and standard deviations of the natural frequencies and MAC between the AVT results and the updated FEM predictions. The dynamically updated FEM of the bridge can better represent its structural dynamics and serve as a baseline in long-term health monitoring, condition assessment and damage identification over the service life of the bridge.

  11. Updated Starshade Technology Gap List

    Science.gov (United States)

    Crill, Brendan P.; Siegler, Nicholas

    2017-01-01

    NASA's Exoplanet Exploration Program (ExEP) guides the development of technology that enables the direct imaging and characterization of exo-Earths in the habitable zone of their stars, for future space observatories. Here we present the Starshade portion of the 2017 ExEP Enabling Technology Gap List, an annual update to ExEP's list of of technology to be advanced in the next 1-5 years. A Starshade is an external occulter on an independent spacecraft, allowing a space telescope to achieve exo-Earth imaging contrast requirements by blocking starlight before it enters the telescope. Building and operating a Starshade requires new technology: the occulter is a structure tens of meters in diameter that must be positioned precisely at a distance of tens of thousands of kilometers from the telescope. We review the current state-of-the-art performance and the performance level that must be achieved for a Starshade.

  12. [An update on Lassa virus].

    Science.gov (United States)

    Leparc-Goffart, I; Emonet, S F

    2011-12-01

    Lassa virus, the etiologic agent of Lassa hemorrhagic fever, infects 100,000 to 300,000 people every year in West Africa with an overall mortality rate ranging from 1 to 2%. It was discovered in 1969 and remains a significant public health risk in endemic areas. Because airborne transmission is possible and mortality can be high under certain conditions, Lassa virus has been classified as a category A bioterrorism agent. Early diagnosis is difficult due to insidious non-specific onset and to the great genetic divergence of the virus that makes RT-PCR assays unreliable. The lack of proper diagnostic tools promotes nosocomial infection and diminishes the efficacy of treatment. Recently, numerous advances have been made in the development of both diagnostic and vaccination techniques. The purpose of this review is to present an update on that research as well as the current epidemiology of Lassa virus.

  13. Update in pulmonary arterial hypertension.

    Science.gov (United States)

    Mejía Chew, C R; Alcolea Batres, S; Ríos Blanco, J J

    2016-11-01

    Pulmonary arterial hypertension is a rare and progressive disease that mainly affects the pulmonary arterioles (precapillary), regardless of the triggering aetiology. The prevalence of pulmonary hypertension and pulmonary arterial hypertension in Spain is estimated at 19.2 and 16 cases per million inhabitants, respectively. The diagnosis of pulmonary arterial hypertension is based on haemodynamic criteria (mean pulmonary artery pressure ≥25mmHg, pulmonary capillary wedge pressure ≤15mmHg and pulmonary vascular resistance >3 Wood units) and therefore requires the implementation of right cardiac catheterisation. Sequential therapy with a single drug has been used in clinical practice. However, recent European guidelines recommend combined initial therapy in some situations. This review conducts a critical update of our knowledge of this disease according to the latest guidelines and recommendations.

  14. Sepsis: An update in management.

    Science.gov (United States)

    Galen, Benjamin T; Sankey, Christopher

    2015-11-01

    Hospitalists are a critical link in providing evidence-based care for patients with sepsis across the disease spectrum, from early recognition to recovery. The past decade of sepsis research has led to significant findings that will change clinical practice for hospital medicine practitioners. Although the incidence of severe sepsis in the United States has continued to rise, in-hospital mortality has declined. Management of the spectrum of sepsis disorders is no longer restricted to the intensive care unit (ICU). This review article will provide an update in the management of sepsis for hospitalists based on recently published pivotal studies. The expanding evidence base in sepsis includes early goal-directed therapy/clinical endpoints/sepsis bundles, antibiotics and source control, volume resuscitation, ICU considerations (including the use of insulin and corticosteroids), mortality/complications, and the newly recognized condition of "sepsis survivorship".

  15. Office Operative Hysteroscopy - an Update.

    Science.gov (United States)

    Salazar, Christina Alicia; Isaacson, Keith

    2017-08-10

    Hysteroscopy is considered the gold standard for evaluation of intracavitary pathology associated with both pre- and postmenopausal patients with abnormal uterine bleeding as well as part of the evaluation of infertility patients with suspected cavity abnormalities. Office-based operative hysteroscopy allows patients to resume activities immediately and successfully integrates clinical practice into a "see and treat" modality, avoiding the added risks of undergoing anesthesia and the inconvenience of going to the operating room. For 2017, the Center for Medicare and Medical Services has incorporated a substantial increase in the reimbursement for a select number of office-based hysteroscopic procedures. This review provides an update on office hysteroscopy indications, equipment, and procedures as well as reviews management of complications that may arise within an office-based practice. Copyright © 2017. Published by Elsevier Inc.

  16. [Antiphospholipid syndrome diagnosis: an update].

    Science.gov (United States)

    Visseaux, Benoit; Masliah-Planchon, Julien; Fischer, Anne-Marie; Darnige, Luc

    2011-01-01

    The antiphospholipid syndrome (APS) is characterized by arterial and/or venous thrombosis and pregnancy morbidity in association with the persistent presence of autoantibodies called antiphospholipid antibodies (APAs). APAs are a heterogeneous group of circulating autoantibodies that can be detected either by phospholipid-dependent coagulation test for lupus anticoagulant (LA) or ELISA test for anticardiolipin and anti-β2GPI antibodies. In 2006, the revised criteria for the diagnosis of APS introduce the anti-β2GPI antibodies as a new biological criterion and highlight the necessity to increase the interval between two positive APA test from 6 to 12 weeks. However, despite these updated criteria, the diagnosis of APS remains challenging and we proposed here to make an overview of the latest evolution in the diagnosis of this syndrome.

  17. Malnutrition and infection: an update.

    Science.gov (United States)

    Solomons, Noel W

    2007-10-01

    The original Scrimshaw, Taylor and Gordon conceptual framework for the interaction of nutrition and infection has well served the scientific community for almost half a century. At its core is the notion of synergistic (mutually reinforcing) and antagonistic (mutually nullifying) influences of the malnourished state on infectious conditions and vice versa. Research on a series of advancing fronts, however, has allowed the incorporation of both relevant public health issues (parasitosis, emerging infectious diseases, obesity and overweight, etc.) and advancing science (molecular immunology, oxidation biology, multiple micronutrient deficiencies, etc.). The present review is an interpretative update on close to 50 years of demographic and epidemiological evolution in the field of human nutrition and the implications for the interaction in the context of microbiological and immunological developments on the infectious side of the dialectic.

  18. An Update on Radio Supernovae

    Science.gov (United States)

    van Dyk, Schuyler D.; Sramek, Richard A.; Weiler, Kurt W.; Montes, Marcos J.; Panagia, Nino

    The radio emission from supernovae (SNe) is nonthermal synchrotron radiation of high brightness temperature, with a ``turn-on'' delay at longer wavelengths, power-law decline after maximum with index beta, and spectral index alpha asymptotically decreasing with time to a final, optically thin value. Radio supernovae (RSNe) are best described by the Chevalier (1982) ``mini-shell'' model, with modifications by Weiler \\etal\\ (1990). RSNe observations provide a valuable probe of the SN circumstellar environment and constraints on progenitor masses. We present a progress report on a number of recent RSNe, as well as on new behavior from RSNe 1979C and 1980K, and on RSNe as potential distance indicators. In particular, we present updated radio light curves for SN 1993J in M81.

  19. Coronary microvascular dysfunction: an update

    Science.gov (United States)

    Crea, Filippo; Camici, Paolo G.; Bairey Merz, Cathleen Noel

    2014-01-01

    Many patients undergoing coronary angiography because of chest pain syndromes, believed to be indicative of obstructive atherosclerosis of the epicardial coronary arteries, are found to have normal angiograms. In the past two decades, a number of studies have reported that abnormalities in the function and structure of the coronary microcirculation may occur in patients without obstructive atherosclerosis, but with risk factors or with myocardial diseases as well as in patients with obstructive atherosclerosis; furthermore, coronary microvascular dysfunction (CMD) can be iatrogenic. In some instances, CMD represents an epiphenomenon, whereas in others it is an important marker of risk or may even contribute to the pathogenesis of cardiovascular and myocardial diseases, thus becoming a therapeutic target. This review article provides an update on the clinical relevance of CMD in different clinical settings and also the implications for therapy. PMID:24366916

  20. Sprucing up the site - update

    CERN Multimedia

    2009-01-01

    As mentioned in a previous article the Bulletin will be publishing regular short updates following the consolidation work going on around the CERN sites: All internal lighting is being replaced in the office buildings on the Prevessin site. Work has started in building 866 and will move to 864 and 865 later. New energy-efficient lights are being installed, which will reduce electricity consumption by 30 -50%, and in the common areas like corridors the lighting will be switched on by motion sensors. Also in the Prevessin site, the lines in the car parks are being repainted. This will continue in the Meyrin site later. Work has started in Building 30 to completely refurbish the AT Auditorium.

  1. 跨部门合作机制对我国政府的启示%Inspiration of the Cross -departmental Collaboration System to Our Government

    Institute of Scientific and Technical Information of China (English)

    陈曦

    2015-01-01

    The hierarchical model,which was proposed by the sociologist Max Weber and which emphasized the supply of pub-lic service to citizens and the achievement of public policy objectives through the top -down vertical -chain executive order had been the main administrative form adopted by governments across the world.Their administrative practice proved that this tradi-tional model indeed played an active role in quite a long period of time.However,since 1980s with the rapid development of global economy,science and technology and the awakening of citizenship,the needs and problems of the society and the public are also showing characteristics of complexity,dynamics and diversity.All of the governmental departments have to change their management mode according to the ever -changing interests and demands of the public and the society.One of the obvious fea-tures is that governments are gradually changing their vertical administrative model,namely,being only responsible for their own department and continuously deepening the specialized division,into focusing on the development of coordination and cooperation between different government departments.From an international point of view,inter -departmental cooperation has become a hot issue in the management and governance of governments.And it is also the key and difficult point for them to establish and improve the related institutions and mechanisms.%伴随着全球经济的快速发展,科学技术的日新月异,公民意识的不断觉醒,社会与公众的需要和问题也日益呈现复杂性、动态性、多元性等特点,各国政府部门都不得不依据社会与公众不断发展的利益诉求和不断发展的社会环境改变管理方式,进行管理改革。其中一个比较明显的特征就是,各国政府都渐渐地将以往垂直管理、仅对本部门职责范围内事务负责并不断加深部门专业化的行政模式向更多地关注不同政府部门间的协调合作发展

  2. EFSA Panel on Biological Hazards (BIOHAZ); Scientific Opinion on the maintenance of the list of QPS biological agents intentionally added to food and feed (2011 update)

    DEFF Research Database (Denmark)

    Hald, Tine

    agents is reviewed and updated annually. Therefore, the only valid list is the one in the most recent scientific opinion. The 2011 update reviews microorganisms previously assessed including bacteria, yeasts, filamentous fungi and viruses used for plant protection purposes and confirms the previous...... this qualification applies for yeast strains able to grow above 37 °C’. The body of knowledge of filamentous fungi and enterococci was updated and their ineligibility for the QPS list confirmed....

  3. Update on the female athlete triad.

    Science.gov (United States)

    Barrack, Michelle T; Ackerman, Kathryn E; Gibbs, Jenna C

    2013-06-01

    Updated prevalence estimates of all 3 components of the Female Athlete Triad, a syndrome characterized by low energy availability, functional hypothalamic amenorrhea, and osteoporosis, is low (0 %-16 %), however, estimates of 1 or 2 concurrent components approach 50 %-60 % among certain athlete groups. Recent research identifies components of the Triad among female adolescent athletes, particularly those participating in leanness sports, such as endurance running. This is alarming, as adolescents require adequate nutrition and normal hormone function to optimize bone mineral gains during this critical developmental period. Current literature highlights new assessments, such as measurements of bone microarchitecture and hormone levels to better evaluate bone strength and the hormonal and metabolic profile of athletes with and at risk for the Triad. Recent data also provides support for additional potential consequences of the Triad, such as endothelial dysfunction and related cardiovascular effects, stress fractures, and musculoskeletal injuries. Additional prospective research is needed to evaluate long-term indicators and consequences of the Triad and identify effective behavioral treatment strategies.

  4. The Finnish Twin Cohort Study: an update.

    Science.gov (United States)

    Kaprio, Jaakko

    2013-02-01

    In 2002 and 2006, review papers have described the Finnish Twin Cohort and studies conducted on these population-based, longitudinal data sets with extensive follow-up data. Three cohorts have been established: the older twin cohort in the 1970s, and the Finntwin12 and Finntwin16 studies initiated in the 1990s. The present review provides on update on the latest data collections conducted since the previous review. These cover the fourth waves of data collection in the older cohort (twins born before 1958) and Finntwin12 (twins born 1983-1987). The fifth wave of data collection in Finntwin16 (twins born 1975-1979) also included assessments of their spouses/partners. An analysis of mortality in the older cohort from 1975 to 2009 indicates that the mortality of adult twins (as individuals) does not differ from the population at large. Based on the cohorts, many sub-studies with more detailed phenotyping and collection of omics data have been conducted or are in progress. We also contribute to numerous national and international collaborations.

  5. Training working memory updating in young adults.

    Science.gov (United States)

    Linares, Rocío; Borella, Erika; Lechuga, M Teresa; Carretti, Barbara; Pelegrina, Santiago

    2017-03-09

    Working memory updating (WMU) is a core mechanism in the human mental architecture and a good predictor of a wide range of cognitive processes. This study analyzed the benefits of two different WMU training procedures, near transfer effects on a working memory measure, and far transfer effects on nonverbal reasoning. Maintenance of any benefits a month later was also assessed. Participants were randomly assigned to: an adaptive training group that performed two numerical WMU tasks during four sessions; a non-adaptive training group that performed the same tasks but on a constant and less demanding level of difficulty; or an active control group that performed other tasks unrelated with working memory. After the training, all three groups showed improvements in most of the tasks, and these benefits were maintained a month later. The gain in one of the two WMU measures was larger for the adaptive and non-adaptive groups than for the control group. This specific gain in a task similar to the one trained would indicate the use of a better strategy for performing the task. Besides this nearest transfer effect, no other transfer effects were found. The adaptability of the training procedure did not produce greater improvements. These results are discussed in terms of the training procedure and the feasibility of training WMU.

  6. Updating Recursive XML Views of Relations

    Institute of Scientific and Technical Information of China (English)

    Byron Choi; Gao Cong; Wenfei Fan; Stratis D. Viglas

    2008-01-01

    This paper investigates the view update problem for XML views published from relational data. We consider XML views defined in terms of mappings directed by possibly recursive DTDs compressed into DAGs and stored in relations.We provide new techniques to efficiently support XML view updates specified in terms of Xpath expressions with recursion and complex filters. The interaction between Xpath recursion and DAG compression of XML views makes the analysis of the XML view update problem rather intriguing. Furthermore, many issues are still open even for relational view updates,and need to be explored. In response to these, on the XML side, we revise the notion of side effects and update semantics based on the semantics of XML views, and present efficient algorithms to translate XML updates to relational view updates.On the relational side, we propose a mild condition on SPJ views, and show that under this condition the analysis of deletions on relational views becomes PTIME while the insertion analysis is NP-complete. We develop an efficient algorithm to process relational view deletions, and a heuristic algorithm to handle view insertions. Finally, we present an experimental study to verify the effectiveness of our techniques.

  7. An updated weight of evidence approach to the aquatic hazard assessment of Bisphenol A and the derivation a new predicted no effect concentration (Pnec) using a non-parametric methodology.

    Science.gov (United States)

    Wright-Walters, Maxine; Volz, Conrad; Talbott, Evelyn; Davis, Devra

    2011-01-15

    An aquatic hazard assessment establishes a derived predicted no effect concentration (PNEC) below which it is assumed that aquatic organisms will not suffer adverse effects from exposure to a chemical. An aquatic hazard assessment of the endocrine disruptor Bisphenol A [BPA; 2, 2-bis (4-hydroxyphenyl) propane] was conducted using a weight of evidence approach, using the ecotoxicological endpoints of survival, growth and development and reproduction. New evidence has emerged that suggests that the aquatic system may not be sufficiently protected from adverse effects of BPA exposure at the current PNEC value of 100 μg/L. It is with this background that; 1) An aquatic hazard assessment for BPA using a weight of evidence approach, was conducted, 2) A PNEC value was derived using a non parametric hazardous concentration for 5% of the specie (HC(5)) approach and, 3) The derived BPA hazard assessment values were compared to aquatic environmental concentrations for BPA to determine, sufficient protectiveness from BPA exposure for aquatic species. A total of 61 studies yielded 94 no observed effect concentration (NOEC) and a toxicity dataset, which suggests that the aquatic effects of mortality, growth and development and reproduction are most likely to occur between the concentrations of 0.0483 μg/L and 2280 μg/L. This finding is within the range for aquatic adverse estrogenic effects reported in the literature. A PNEC of 0.06 μg/L was calculated. The 95% confidence interval was found to be (0.02, 3.40) μg/L. Thus, using the weight of evidence approach based on repeated measurements of these endpoints, the results indicate that currently observed BPA concentrations in surface waters exceed this newly derived PNEC value of 0.06 μg/L. This indicates that some aquatic receptors may be at risk for adverse effects on survival, growth and development and reproduction from BPA exposure at environmentally relevant concentrations. Copyright © 2010 Elsevier B.V. All rights

  8. Dynamic Model Updating Using Virtual Antiresonances

    Directory of Open Access Journals (Sweden)

    Walter D’Ambrogio

    2004-01-01

    Full Text Available This paper considers an extension of the model updating method that minimizes the antiresonance error, besides the natural frequency error. By defining virtual antiresonances, this extension allows the use of previously identified modal data. Virtual antiresonances can be evaluated from a truncated modal expansion, and do not correspond to any physical system. The method is applied to the Finite Element model updating of the GARTEUR benchmark, used within an European project on updating. Results are compared with those previously obtained by estimating actual antiresonances after computing low and high frequency residuals, and with results obtained by using the correlation (MAC between identified and analytical mode shapes.

  9. Cardiac Safety Research Consortium: can the thorough QT/QTc study be replaced by early QT assessment in routine clinical pharmacology studies? Scientific update and a research proposal for a path forward.

    Science.gov (United States)

    Darpo, Borje; Garnett, Christine; Benson, Charles T; Keirns, James; Leishman, Derek; Malik, Marek; Mehrotra, Nitin; Prasad, Krishna; Riley, Steve; Rodriguez, Ignacio; Sager, Philip; Sarapa, Nenad; Wallis, Robert

    2014-09-01

    The International Conference on Harmonization E14 guidance for the clinical evaluation of QT/QTc interval prolongation requires almost all new drugs to undergo a dedicated clinical study, primarily in healthy volunteers, the so-called TQT study. Since 2005, when the E14 guidance was implemented in United States and Europe, close to 400 TQT studies have been conducted. In February 2012, the Cardiac Safety Research Consortium held a think tank meeting at Food and Drug Administration's White Oak campus to discuss whether "QT assessment" can be performed as part of routine phase 1 studies. Based on these discussions, a group of experts convened to discuss how to improve the confidence in QT data from early clinical studies, for example, the First-Time-in-Human trial, through collection of serial electrocardiograms and pharmacokinetic samples and the use of exposure response analysis. Recommendations are given on how to design such "early electrocardiogram assessment," and the limitation of not having a pharmacologic-positive control in these studies is discussed. A research path is identified toward collecting evidence to replace or provide an alternative to the dedicated TQT study.

  10. Epidemiology of Hypertension in Canada: An Update.

    Science.gov (United States)

    Padwal, Raj S; Bienek, Asako; McAlister, Finlay A; Campbell, Norm R C

    2016-05-01

    High blood pressure (BP) is the leading cause of death and disability in the world. The objective of this analysis was to perform a detailed update of the epidemiology of hypertension in Canada. Five population-based data sources were analyzed. We used the Canadian Health Measures Survey to determine the latest directly measured prevalence, awareness, and control estimates (2012-2013); the National Population Health Survey, and Canadian Community Health Survey to assess crude and age-standardized self-reported prevalence (1994-2013); the Canadian Chronic Disease Surveillance System to assess administrative data-ascertained prevalence and mortality trends (1998-2010); and Intercontinental Medical Statistics Health data to examine antihypertensive drug-prescribing trends and costs (2007-2014). In 2012-2013, the prevalence of hypertension (defined as drug treatment for high BP or BP ≥ 140/90 mm Hg) in Canadian adults was 22.6%, and the proportion of disease controlled was 68.1%. In Canadians with diabetes, the prevalence (defined as drug treatment or BP ≥ 130/80 mm Hg) was 67.1%, and 60.1% of cases were controlled. Self-reported hypertension prevalence has increased by approximately 2-fold over nearly 2 decades. Age-standardized mortality rates are falling in hypertensive Canadians (from 9.4 to 7.9 deaths per 1000 individuals), but to a lesser extent than in nonhypertensive individuals. Total antihypertensive drug prescription volume has increased steadily since 2007 amid falling drug costs. Hypertension prevalence in Canada continues to rise. Increased use of antihypertensive drugs and improvements in control are apparent. Coordinated efforts to further improve the treatment and control of hypertension in Canada are needed. Copyright © 2016 Canadian Cardiovascular Society. Published by Elsevier Inc. All rights reserved.

  11. Screening of the hearing of newborns - Update

    Directory of Open Access Journals (Sweden)

    von Voß, Hubertus

    2006-11-01

    Full Text Available Introduction: Permanent congenital bilateral hearing loss (CHL of moderate or greater degree (≥40 dB HL is a rare disease, with a prevalence of about 1 to 3 per 1000 births. However, it is one of the most frequent congenital diseases. Reliance on physician observation and parental recognition has not been successful in the past in detecting significant hearing loss in the first year of life. With this strategy significant hearing losses have been detected in the second year of life. With two objective technologies based on physiologic response to sound, otoacoustic emissions (OAE and auditory brainstem response (ABR hearing screening in the first days of life is made possible. Objectives: The objective of this health technology assessment report is to update the evaluation on clinical effectiveness and cost-effectiveness of newborn hearing screening programs. Universal newborn hearing screening (UHNS (i, selective screening of high risk newborns (ii, and the absence of a systematic screening program are compared for age at identification and age at hearing aid fitting of children with hearing loss. Secondly the potential benefits of early intervention are analysed. Costs and cost-effectiveness of newborn hearing screening programs are determined. This report is intended to make a contribution to the decision making whether and under which conditions a newborn hearing screening program should be reimbursed by the statutory sickness funds in Germany. Methods: This health technology assessment report updates a former health technology assessment (Kunze et al. 2004 [1]. A systematic review of the literature was conducted, based on a documented search and selection of the literature using predefined inclusion and exclusion criteria and a documented extraction and appraisal of the included studies. To assess the cost-effectiveness of the different screening strategies in Germany the decision analytic Markov state model which had been developed in

  12. 2016 Focused Update of the Canadian Cardiovascular Society Guidelines for the Management of Atrial Fibrillation.

    Science.gov (United States)

    Macle, Laurent; Cairns, John; Leblanc, Kori; Tsang, Teresa; Skanes, Allan; Cox, Jafna L; Healey, Jeff S; Bell, Alan; Pilote, Louise; Andrade, Jason G; Mitchell, L Brent; Atzema, Clare; Gladstone, David; Sharma, Mike; Verma, Subodh; Connolly, Stuart; Dorian, Paul; Parkash, Ratika; Talajic, Mario; Nattel, Stanley; Verma, Atul

    2016-10-01

    The Canadian Cardiovascular Society (CCS) Atrial Fibrillation (AF) Guidelines Committee provides periodic reviews of new data to produce focused updates that address clinically important advances in AF management. This 2016 Focused Update deals with: (1) the management of antithrombotic therapy for AF patients in the context of the various clinical presentations of coronary artery disease; (2) real-life data with non-vitamin K antagonist oral anticoagulants; (3) the use of antidotes for the reversal of non-vitamin K antagonist oral anticoagulants; (4) digoxin as a rate control agent; (5) perioperative anticoagulation management; and (6) AF surgical therapy including the prevention and treatment of AF after cardiac surgery. The recommendations were developed with the same methodology used for the initial 2010 guidelines and the 2012 and 2014 Focused Updates. Using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) standards, individual studies and literature were reviewed for quality and bias; the literature review process and evidence tables are included in the Supplementary Material, and on the CCS Web site. The section on concomitant AF and coronary artery disease was developed in collaboration with the CCS Antiplatelet Guidelines Committee. Details of the updated recommendations are presented, along with their background and rationale. This document is linked to an updated summary of all CCS AF Guidelines recommendations, from 2010 to the present 2016 Focused Update.

  13. Closing the loop: an interactive action-research conference format for delivering updated medical information while eliciting Latina patient/family experiences and psychosocial needs post-genetic cancer risk assessment.

    Science.gov (United States)

    Macdonald, Deborah J; Deri, Julia; Ricker, Charité; Perez, Martin A; Ogaz, Raquel; Feldman, Nancy; Viveros, Lori A; Paz, Benjamin; Weitzel, Jeffrey N; Blazer, Kathleen R

    2012-09-01

    A patient/family-centered conference was conducted at an underserved community hospital to address Latinas' post-genetic cancer risk assessment (GCRA) medical information and psychosocial support needs, and determine the utility of the action research format. Latinas seen for GCRA were recruited to a half-day conference conducted in Spanish. Content was partly determined from follow-up survey feedback. Written surveys, interactive discussions, and Audience Response System (ARS) queries facilitated the participant-healthcare professional action research process. Analyses included descriptive statistics and thematic analysis. The 71 attendees (41 patients and 27 relatives/friends) were primarily non-US born Spanish-speaking females, mean age 43 years. Among patients, 73 % had a breast cancer history; 85 % had BRCA testing (49 % BRCA+). Nearly all (96 %) attendees completed the conference surveys and ARS queries; ≥48 % participated in interactive discussions. Most (95 %) agreed that the format met their personal interests and expectations and provided useful information and resources. Gaps/challenges identified in the GCRA process included pre-consult anxiety, uncertainty about reason for referral and expected outcomes, and psychosocial needs post-GCRA, such as absorbing and disseminating risk information to relatives and concurrently coping with a recent cancer diagnosis. The combined action research and educational conference format was innovative and effective for responding to continued patient information needs and addressing an important data gap about support needs of Latina patients and family members following genetic cancer risk assessment. Findings informed GCRA process improvements and provide a basis for theory-driven cancer control research.

  14. Updating neutrino magnetic moment constraints

    CERN Document Server

    Canas, B C; Parada, A; Tortola, M; Valle, J W F

    2015-01-01

    In this paper we provide an updated analysis of the neutrino magnetic moments (NMMs), discussing both the constraints on the magnitudes of the three transition moments Lambda_i as well as the role of the CP violating phases present both in the mixing matrix and in the NMM matrix. The scattering of solar neutrinos off electrons in Borexino provides the most stringent restrictions, due to its robust statistics and the low energies observed, below 1 MeV. Our new limit on the effective neutrino magnetic moment which follows from the most recent Borexino data is 3.1 x 10^-11 mu_B at 90% C.L. This corresponds to the individual transition magnetic moment constraints: |Lambda_1| < 5.6 x10^-11 mu_B, |Lambda_2| < 4.0 x 10^-11 mu_B, and |Lambda_3| < 3.1 x 10^-11 mu_B (90% C.L.), irrespective of any complex phase. Indeed, the incoherent admixture of neutrino mass eigenstates present in the solar flux makes Borexino insensitive to the Majorana phases present in the NMM matrix. For this reason we also provide a gl...

  15. Stuttering: Clinical and research update.

    Science.gov (United States)

    Perez, Hector R; Stoeckle, James H

    2016-06-01

    To provide an update on the epidemiology, genetics, pathophysiology, diagnosis, and treatment of developmental stuttering. The MEDLINE and Cochrane databases were searched for past and recent studies on the epidemiology, genetics, pathophysiology, diagnosis, and treatment of developmental stuttering. Most recommendations are based on small studies, limited-quality evidence, or consensus. Stuttering is a speech disorder, common in persons of all ages, that affects normal fluency and time patterning of speech. Stuttering has been associated with differences in brain anatomy, functioning, and dopamine regulation thought to be due to genetic causes. Attention to making a correct diagnosis or referral in children is important because there is growing consensus that early intervention with speech therapy for children who stutter is critical. For adults, stuttering can be associated with substantial psychosocial morbidity including social anxiety and low quality of life. Pharmacologic treatment has received attention in recent years, but clinical evidence is limited. The mainstay of treatment for children and adults remains speech therapy. A growing body of research has attempted to uncover the pathophysiology of stuttering. Referral for speech therapy remains the best option for children and adults. Copyright© the College of Family Physicians of Canada.

  16. IDSA releases updated coccidioidomycosis guidelines

    Directory of Open Access Journals (Sweden)

    Robbins RA

    2016-09-01

    Full Text Available No abstract available. Article truncated at 150 words. The Infectious Diseases Society of America (IDSA has released updated Guidelines for the Treatment of Coccidioidomycosis, also known as cocci or Valley Fever (1. Coccidioidomycosis is a fungal infection endemic to the southwestern United States and a common cause of pneumonia and pulmonary nodules in this area. However, the infection can disseminate systemically especially in immunocompromised hosts and certain ethnic populations resulting in a variety of pulmonary and extrapulmonary complications. In addition to recommendations for these complications, the new guidelines address management of special at-risk populations, preemptive management strategies in at-risk populations and after unintentional laboratory exposure. The guidelines also suggest shorter courses of antibiotics for hospitalized patients and more ambulatory treatment for most individuals who have contracted Valley Fever. The panel was led by John N. Galgiani, MD, director of the Valley Fever Center for Excellence at the University of Arizona Health Sciences. Galgiani led a panel of 16 ...

  17. Extraglottic airway devices: technology update

    Directory of Open Access Journals (Sweden)

    Sharma B

    2017-08-01

    Full Text Available Bimla Sharma, Chand Sahai, Jayashree Sood Department of Anaesthesiology, Pain and Perioperative Medicine, Sir Ganga Ram Hospital, New Delhi, India Abstract: Extraglottic airway devices (EADs have revolutionized the field of airway management. The invention of the laryngeal mask airway was a game changer, and since then, there have been several innovations to improve the EADs in design, functionality, safety and construction material. These have ranged from changes in the shape of the mask, number of cuffs and material used, like rubber, polyvinylchloride and latex. Phthalates, which were added to the construction material in order to increase device flexibility, were later omitted when this chemical was found to have serious adverse reproductive outcomes. The various designs brought out by numerous companies manufacturing EADs resulted in the addition of several devices to the airway market. These airway devices were put to use, many of them with inadequate or no evidence base regarding their efficacy and safety. To reduce the possibility of compromising the safety of the patient, the Difficult Airway Society (DAS formed the Airway Device Evaluation Project Team (ADEPT to strengthen the evidence base for airway equipment and vet the new extraglottic devices. A preuse careful analysis of the design and structure may help in better understanding of the functionality of a particular device. In the meantime, the search for the ideal EAD continues. Keywords: extraglottic airway devices, laryngeal mask airway, other extraglottic airway devices, safety, technology update

  18. Congenital Chagas disease: an update.

    Science.gov (United States)

    Carlier, Yves; Sosa-Estani, Sergio; Luquetti, Alejandro O; Buekens, Pierre

    2015-05-01

    Congenital infection with Trypanosoma cruzi is a global problem, occurring on average in 5% of children born from chronically infected mothers in endemic areas, with variations depending on the region. This presentation aims to focus on and update epidemiological data, research methods, involved factors, control strategy and possible prevention of congenital infection with T. cruzi. Considering that etiological treatment of the child is always effective if performed before one year of age, the diagnosis of infection in pregnant women and their newborns has to become the standard of care and integrated into the surveillance programs of syphilis and human immunodeficiency virus. In addition to the standard tests, polymerase chain reaction performed on blood of neonates of infected mothers one month after birth might improve the diagnosis of congenital infection. Recent data bring out that its transmission can be prevented through treatment of infected women before they become pregnant. The role of parasite genotypes and host genetic factors in parasite transmission and development of infection in foetuses/neonates has to be more investigated in order to better estimate the risk factors and impact on health of congenital infection with T. cruzi.

  19. Congenital Chagas disease: an update

    Directory of Open Access Journals (Sweden)

    Yves Carlier

    2015-05-01

    Full Text Available Congenital infection with Trypanosoma cruzi is a global problem, occurring on average in 5% of children born from chronically infected mothers in endemic areas, with variations depending on the region. This presentation aims to focus on and update epidemiological data, research methods, involved factors, control strategy and possible prevention of congenital infection with T. cruzi. Considering that etiological treatment of the child is always effective if performed before one year of age, the diagnosis of infection in pregnant women and their newborns has to become the standard of care and integrated into the surveillance programs of syphilis and human immunodeficiency virus. In addition to the standard tests, polymerase chain reaction performed on blood of neonates of infected mothers one month after birth might improve the diagnosis of congenital infection. Recent data bring out that its transmission can be prevented through treatment of infected women before they become pregnant. The role of parasite genotypes and host genetic factors in parasite transmission and development of infection in foetuses/neonates has to be more investigated in order to better estimate the risk factors and impact on health of congenital infection with T. cruzi.

  20. Vasectomy reversal: a clinical update

    Directory of Open Access Journals (Sweden)

    Abhishek P Patel

    2016-01-01

    Full Text Available Vasectomy is a safe and effective method of contraception used by 42-60 million men worldwide. Approximately 3%-6% of men opt for a vasectomy reversal due to the death of a child or divorce and remarriage, change in financial situation, desire for more children within the same marriage, or to alleviate the dreaded postvasectomy pain syndrome. Unlike vasectomy, vasectomy reversal is a much more technically challenging procedure that is performed only by a minority of urologists and places a larger financial strain on the patient since it is usually not covered by insurance. Interest in this procedure has increased since the operating microscope became available in the 1970s, which consequently led to improved patency and pregnancy rates following the procedure. In this clinical update, we discuss patient evaluation, variables that may influence reversal success rates, factors to consider in choosing to perform vasovasostomy versus vasoepididymostomy, and the usefulness of vasectomy reversal to alleviate postvasectomy pain syndrome. We also review the use of robotics for vasectomy reversal and other novel techniques and instrumentation that have emerged in recent years to aid in the success of this surgery.

  1. Updating neutrino magnetic moment constraints

    Directory of Open Access Journals (Sweden)

    B.C. Cañas

    2016-02-01

    Full Text Available In this paper we provide an updated analysis of the neutrino magnetic moments (NMMs, discussing both the constraints on the magnitudes of the three transition moments Λi and the role of the CP violating phases present both in the mixing matrix and in the NMM matrix. The scattering of solar neutrinos off electrons in Borexino provides the most stringent restrictions, due to its robust statistics and the low energies observed, below 1 MeV. Our new limit on the effective neutrino magnetic moment which follows from the most recent Borexino data is 3.1×10−11μB at 90% C.L. This corresponds to the individual transition magnetic moment constraints: |Λ1|≤5.6×10−11μB, |Λ2|≤4.0×10−11μB, and |Λ3|≤3.1×10−11μB (90% C.L., irrespective of any complex phase. Indeed, the incoherent admixture of neutrino mass eigenstates present in the solar flux makes Borexino insensitive to the Majorana phases present in the NMM matrix. For this reason we also provide a global analysis including the case of reactor and accelerator neutrino sources, presenting the resulting constraints for different values of the relevant CP phases. Improved reactor and accelerator neutrino experiments will be needed in order to underpin the full profile of the neutrino electromagnetic properties.

  2. Labor law update--Part 1.

    Science.gov (United States)

    Fiesta, J

    1997-01-01

    To ensure proper actions when making managerial decisions, nurses must be aware of labor laws and the policies that apply to them. Part 1 of "Labor Law Update" discusses public policy considerations and gender, racial and pregnancy discrimination.

  3. Model Updating Nonlinear System Identification Toolbox Project

    Data.gov (United States)

    National Aeronautics and Space Administration — ZONA Technology proposes to develop an enhanced model updating nonlinear system identification (MUNSID) methodology by adopting the flight data with state-of-the-art...

  4. CDC Updates Spending Plans to Combat Zika

    Science.gov (United States)

    ... 161541.html CDC Updates Spending Plans to Combat Zika Some goals: prepare states for future outbreaks, and ... dollars to prepare states and cities for future Zika virus outbreaks, and to track the effects of ...

  5. Rapid Update Cycle (RUC) [13 km

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Rapid Update Cycle (RUC) weather forecast model was developed by the National Centers for Environmental Prediction (NCEP). On May 1, 2012, the RUC was replaced...

  6. Rapid Update Cycle (RUC) [20 km

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Rapid Update Cycle (RUC) weather forecast model was developed by the National Centers for Environmental Prediction (NCEP). On May 1, 2012, the RUC was replaced...

  7. Ecological Subsections for Northern Alaska, 2012 update

    Data.gov (United States)

    Arctic Landscape Conservation Cooperative — This data set represents an updated Ecological Subsection Map for Northern Alaska. This 2012 revision focused on completing the incompletely mapped portion of the...

  8. Earth Observing System Covariance Realism Updates

    Science.gov (United States)

    Ojeda Romero, Juan A.; Miguel, Fred

    2017-01-01

    This presentation will be given at the International Earth Science Constellation Mission Operations Working Group meetings June 13-15, 2017 to discuss the Earth Observing System Covariance Realism updates.

  9. Clinical update on nursing home medicine: 2013.

    Science.gov (United States)

    Messinger-Rapport, Barbara J; Gammack, Julie K; Thomas, David R; Morley, John E

    2013-12-01

    This is the seventh article in the series of Clinical Updates on Nursing Home Care. The topics covered are antiresorptive drugs, hip fracture, hypertension, orthostatic hypotension, depression, undernutrition, anorexia, cachexia, sarcopenia, exercise, pain, and behavioral and psychological symptoms of dementia.

  10. 1990 Kansas Land Cover Patterns Update

    Data.gov (United States)

    Kansas Data Access and Support Center — In 2008, an update of the 1990 Kansas Land Cover Patterns (KLCP) database was undertaken. The 1990 KLCP database depicts 10 general land cover classes for the State...

  11. Bird deterrent and dispersal systems: Research update

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report is a research update on bird deterrent and dispersal systems by the Petroleum Association for Conservation of the Canadian Environment. The purpose of...

  12. Breast Cancer and Estrogen-Alone Update

    Science.gov (United States)

    ... Issues Research News From NIH Breast Cancer and Estrogen-Alone Update Past Issues / Summer 2006 Table of ... version of this page please turn Javascript on. Estrogen-alone hormone therapy does not increase the risk ...

  13. 77 FR 33980 - Proposed FOIA Fee Schedule Update

    Science.gov (United States)

    2012-06-08

    ... NUCLEAR FACILITIES SAFETY BOARD 10 CFR Part 1703 Proposed FOIA Fee Schedule Update AGENCY: Defense Nuclear... the SUPPLEMENTARY INFORMATION to the Board's proposed FOIA Fee Schedule Update published in the... update the FOIA Fee Schedule once every 12 months. Previous Fee Schedule Updates were published in...

  14. An update on the management of chronic lumbar discogenic pain.

    Science.gov (United States)

    Manchikanti, Laxmaiah; Hirsch, Joshua A

    2015-09-01

    Lumbar degenerative disc disease without disc herniation, also known as discogenic pain, is an elusive diagnosis of chronic low back pain. Lumbar provocation discography and fusion surgery have been frequently utilized for several decades as the gold standards for the diagnosis and treatment of symptomatic lumbar discogenic pain, though controversial, based on conjecture, rather than evidence. In addition to lumbar fusion, various other operative and nonoperative modalities of treatments are available in managing chronic lumbar discogenic pain. This review provides an updated assessment of the management of chronic lumbar discogenic pain with a critical look at the many modalities of treatments that are currently available.

  15. Central Venous Disease in Hemodialysis Patients: An Update

    Energy Technology Data Exchange (ETDEWEB)

    Modabber, Milad, E-mail: mmodabber@gmail.com [McMaster University, Michael G. DeGroote School of Medicine (Canada); Kundu, Sanjoy [Scarborough Hospital and Scarborough Vascular Ultrasound, The Vein Institute of Toronto (Canada)

    2013-08-01

    Central venous occlusive disease (CVD) is a common concern among the hemodialysis patient population, with the potential to cause significant morbidity. Endovascular management of CVD, comprising percutaneous balloon angioplasty and bare-metal stenting, has been established as a safe alternative to open surgical treatment. However, these available treatments have poor long-term patency, requiring close surveillance and multiple repeat interventions. Recently, covered stents have been proposed and their efficacy assessed for the treatment of recalcitrant central venous stenosis and obstruction. Moreover, newly proposed algorithms for the surgical management of CVD warrant consideration. Here, we seek to provide an updated review of the current literature on the various treatment modalities for CVD.

  16. Technical Basis for Electromagnetic Compatibility Regulatory Guidance Update

    Energy Technology Data Exchange (ETDEWEB)

    Ewing, Paul D. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Korsah, Kofi [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Harrison, Thomas J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Wood, Richard Thomas [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Mays, Gary T. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2016-03-01

    The objective of this report is to serve as the technical basis document for the next, planned revision of this RG that highlights and provides the rationale for the recommended changes. The structure of this document follows and summarizes the several assessment activities undertaken during the course of this project to evaluate new and updated electromagnetic compatibility (EMC) standards, testing methods and limits, and relevant technology developments being incorporated into plant activities that may have EMI/RFI implications, as well as other specific issues, including impacts of electrostatic discharge (ESD) on safety equipment and impacts on increased usage of wireless devices in nuclear power plants.

  17. Environmental Regulatory Update Table, December 1991

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.M.; Hawkins, G.T.; Salk, M.S.

    1992-01-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  18. Environmental Regulatory Update Table, December 1989

    Energy Technology Data Exchange (ETDEWEB)

    Houlbert, L.M.; Langston, M.E. (Tennessee Univ., Knoxville, TN (USA)); Nikbakht, A.; Salk, M.S. (Oak Ridge National Lab., TN (USA))

    1990-01-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  19. Environmental Regulatory Update Table, November 1991

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.M.; Hawkins, G.T.; Salk, M.S.

    1991-12-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  20. Environmental Regulatory Update Table, August 1991

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.M., Hawkins, G.T.; Salk, M.S.

    1991-09-01

    This Environmental Regulatory Update Table (August 1991) provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  1. Environmental Regulatory Update Table, September 1991

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.M.; Hawkins, G.T.; Salk, M.S.

    1991-10-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  2. Environmental Regulatory Update Table, October 1991

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.M.; Hawkins, G.T.; Salk, M.S.

    1991-11-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  3. Environmental Regulatory Update Table, April 1989

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.; Langston, M.E.; Nikbakht, A.; Salk, M.S.

    1989-05-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  4. Military Specification Updates & Deicing Working Group Initiatives

    Science.gov (United States)

    2011-08-18

    Air Force Petroleum Agency I n t e g r i t y - S e r v i c e - E x c e l l e n c e Military Specification Updates & Deicing Working Group...00-2011 4. TITLE AND SUBTITLE Military Specification Updates & Deicing Working Group Initiatives 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c...Corrosion Runway Deicing Fluid Partnership with Battelle Memorial Institute (lead agency), AFRL/ ASC, Army (CRREL), Navy (NAVAIR), Octagon, AMIL

  5. Environmental Regulatory Update Table, April 1989

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.; Langston, M.E.; Nikbakht, A.; Salk, M.S.

    1989-05-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  6. Environmental regulatory update table, March 1989

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.; Langston, M.E.; Nikbakht, A.; Salk, M.S.

    1989-04-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  7. Environmental Regulatory Update Table, November 1991

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.M.; Hawkins, G.T.; Salk, M.S.

    1991-12-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  8. Portuguese Recommendations for the use of biological therapies in patients with rheumatoid arthritis- 2016 update

    Directory of Open Access Journals (Sweden)

    Catia Duarte

    2017-04-01

    Full Text Available Objective: To update the recommendations for the treatment of Rheumatoid Arthritis (RA with biological therapies, endorsed by the Portuguese Society of Rheumatology (SPR. Methods: These treatment recommendations were formulated by Portuguese rheumatologists based on literature evidence and consensus opinion. At a national meeting the 10 recommendations were discussed and updated. The document resulting from this meeting circulated to all Portuguese rheumatologists, who anonymously voted online on the level of agreement with the recommendations. Results: These recommendations cover general aspects as shared decision, prospective registry in Reuma.pt, assessment of activity and RA impact and treatment objective. Consensus was also achieved regarding specific aspects as initiation of biologic therapy, assessment of response, switching and definition of persistent remission. Conclusion: These recommendations may be used for guidance of treatment with biological therapies in patients with RA. As more evidence becomes available and more therapies are licensed, these recommendations will be updated.

  9. Stochastic model updating using distance discrimination analysis

    Institute of Scientific and Technical Information of China (English)

    Deng Zhongmin; Bi Sifeng; Sez Atamturktur

    2014-01-01

    This manuscript presents a stochastic model updating method, taking both uncertainties in models and variability in testing into account. The updated finite element (FE) models obtained through the proposed technique can aid in the analysis and design of structural systems. The authors developed a stochastic model updating method integrating distance discrimination analysis (DDA) and advanced Monte Carlo (MC) technique to (1) enable more efficient MC by using a response surface model, (2) calibrate parameters with an iterative test-analysis correlation based upon DDA, and (3) utilize and compare different distance functions as correlation metrics. Using DDA, the influence of distance functions on model updating results is analyzed. The proposed sto-chastic method makes it possible to obtain a precise model updating outcome with acceptable cal-culation cost. The stochastic method is demonstrated on a helicopter case study updated using both Euclidian and Mahalanobis distance metrics. It is observed that the selected distance function influ-ences the iterative calibration process and thus, the calibration outcome, indicating that an integra-tion of different metrics might yield improved results.

  10. The role of anti-resonance frequencies from operational modal analysis in finite element model updating

    Science.gov (United States)

    Hanson, D.; Waters, T. P.; Thompson, D. J.; Randall, R. B.; Ford, R. A. J.

    2007-01-01

    Finite element model updating traditionally makes use of both resonance and modeshape information. The mode shape information can also be obtained from anti-resonance frequencies, as has been suggested by a number of researchers in recent years. Anti-resonance frequencies have the advantage over mode shapes that they can be much more accurately identified from measured frequency response functions. Moreover, anti-resonance frequencies can, in principle, be estimated from output-only measurements on operating machinery. The motivation behind this paper is to explore whether the availability of anti-resonances from such output-only techniques would add genuinely new information to the model updating process, which is not already available from using only resonance frequencies. This investigation employs two-degree-of-freedom models of a rigid beam supported on two springs. It includes an assessment of the contribution made to the overall anti-resonance sensitivity by the mode shape components, and also considers model updating through Monte Carlo simulations, experimental verification of the simulation results, and application to a practical mechanical system, in this case a petrol generator set. Analytical expressions are derived for the sensitivity of anti-resonance frequencies to updating parameters such as the ratio of spring stiffnesses, the position of the centre of gravity, and the beam's radius of gyration. These anti-resonance sensitivities are written in terms of natural frequency and mode shape sensitivities so their relative contributions can be assessed. It is found that the contribution made by the mode shape sensitivity varies considerably depending on the value of the parameters, contributing no new information for significant combinations of parameter values. The Monte Carlo simulations compare the performance of the update achieved when using information from: the resonances only; the resonances and either anti-resonance; and the resonances and both

  11. An updated assessment of Symbiodinium spp. that associate with common scleractinian corals from Moorea (French Polynesia) reveals high diversity among background symbionts and a novel finding of clade B

    Science.gov (United States)

    Lecellier, Gaël J.; Saulnier, Denis; Planes, Serge; Gueguen, Yannick; Wirshing, Herman H.; Berteaux-Lecellier, Véronique

    2017-01-01

    The adaptative bleaching hypothesis (ABH) states that, depending on the symbiotic flexibility of coral hosts (i.e., the ability of corals to “switch” or “shuffle” their algal symbionts), coral bleaching can lead to a change in the composition of their associated Symbiodinium community and, thus, contribute to the coral’s overall survival. In order to determine the flexibility of corals, molecular tools are required to provide accurate species delineations and to detect low levels of coral-associated Symbiodinium. Here, we used highly sensitive quantitative (real-time) PCR (qPCR) technology to analyse five common coral species from Moorea (French Polynesia), previously screened using only traditional molecular methods, to assess the presence of low-abundance (background) Symbiodinium spp. Similar to other studies, each coral species exhibited a strong specificity to a particular clade, irrespective of the environment. In addition, however, each of the five species harboured at least one additional Symbiodinium clade, among clades A–D, at background levels. Unexpectedly, and for the first time in French Polynesia, clade B was detected as a coral symbiont. These results increase the number of known coral-Symbiodinium associations from corals found in French Polynesia, and likely indicate an underestimation of the ability of the corals in this region to associate with and/or “shuffle” different Symbiodinium clades. Altogether our data suggest that corals from French Polynesia may favor a trade-off between optimizing symbioses with a specific Symbiodinium clade(s), maintaining associations with particular background clades that may play a role in the ability of corals to respond to environmental change. PMID:28168100

  12. An updated assessment of Symbiodinium spp. that associate with common scleractinian corals from Moorea (French Polynesia) reveals high diversity among background symbionts and a novel finding of clade B.

    Science.gov (United States)

    Rouzé, Héloïse; Lecellier, Gaël J; Saulnier, Denis; Planes, Serge; Gueguen, Yannick; Wirshing, Herman H; Berteaux-Lecellier, Véronique

    2017-01-01

    The adaptative bleaching hypothesis (ABH) states that, depending on the symbiotic flexibility of coral hosts (i.e., the ability of corals to "switch" or "shuffle" their algal symbionts), coral bleaching can lead to a change in the composition of their associated Symbiodinium community and, thus, contribute to the coral's overall survival. In order to determine the flexibility of corals, molecular tools are required to provide accurate species delineations and to detect low levels of coral-associated Symbiodinium. Here, we used highly sensitive quantitative (real-time) PCR (qPCR) technology to analyse five common coral species from Moorea (French Polynesia), previously screened using only traditional molecular methods, to assess the presence of low-abundance (background) Symbiodinium spp. Similar to other studies, each coral species exhibited a strong specificity to a particular clade, irrespective of the environment. In addition, however, each of the five species harboured at least one additional Symbiodinium clade, among clades A-D, at background levels. Unexpectedly, and for the first time in French Polynesia, clade B was detected as a coral symbiont. These results increase the number of known coral-Symbiodinium associations from corals found in French Polynesia, and likely indicate an underestimation of the ability of the corals in this region to associate with and/or "shuffle" different Symbiodinium clades. Altogether our data suggest that corals from French Polynesia may favor a trade-off between optimizing symbioses with a specific Symbiodinium clade(s), maintaining associations with particular background clades that may play a role in the ability of corals to respond to environmental change.

  13. The Adaptation Finance Gap Update - with insights from the INDCs

    DEFF Research Database (Denmark)

    Olhoff, Anne; Bee, Skylar; Puig, Daniel

    In 2014 the United Nations Environment Programme (UNEP) published its first global Adaptation Gap Report (AGR 2014) (UNEP, 2014), which put forward a preliminary framework for assessing adaptation gaps along with an initial assessment in three selected areas: finance, technology and knowledge...... will be published in the spring of 2016. This update is intended as an input to discussions at the 21st session of the Conference of the Parties (COP 21) to the United Nations Framework Convention on Climate Change (UNFCCC). It brings together key findings on adaptation costs and finance from AGR 2014...... and preliminary findings from the 2016 assessment. Furthermore, it draws on insights concerning adaptation costs and related finance needs, as stated in the adaptation components in the Intended Nationally Determined Contributions (INDCs) – the post-2020 climate actions that countries intend to undertake...

  14. Quantifying Update Effects in Citizen-Oriented Software

    Directory of Open Access Journals (Sweden)

    Ion Ivan

    2009-02-01

    Full Text Available Defining citizen-oriented software. Detailing technical issues regarding update process in this kind of software. Presenting different effects triggered by types of update. Building model for update costs estimation, including producer-side and consumer-side effects. Analyzing model applicability on INVMAT – large scale matrix inversion software. Proposing a model for update effects estimation. Specifying ways for softening effects of inaccurate updates.

  15. Obesity management: Update on orlistat

    Directory of Open Access Journals (Sweden)

    Belinda S Drew

    2008-01-01

    Full Text Available Belinda S Drew, Andrew F Dixon, John B DixonCentre for Obesity Research and Education, Monash University, Melbourne, AustraliaAbstract: Over the past 20 years obesity has become a worldwide concern of frightening proportion. The World Health Organization estimates that there are over 400 million obese and over 1.6 billion overweight adults, a figure which is projected to almost double by 2015. This is not a disease restricted to adults – at least 20 million children under the age of 5 years were overweight in 2005 (WHO 2006. Overweight and obesity lead to serious health consequences including coronary artery disease, stroke, type-2 diabetes, heart failure, dyslipidemia, hypertension, reproductive and gastrointestinal cancers, gallstones, fatty liver disease, osteoarthritis and sleep apnea (Padwal et al 2003.Modest weight loss in the obese of between 5% and 10% of bodyweight is associated with improvements in cardiovascular risk profiles and reduced incidence of type 2 diabetes (Goldstein 1992; Avenell et al 2004; Padwal and Majumdar 2007. Orlistat, a gastric and pancreatic lipase inhibitor that reduces dietary fat absorption by approximately 30%, has been approved for use for around ten years (Zhi et al 1994; Hauptman 2000. There is now a growing body of evidence to suggest that Orlistat assists weight loss and that it may also have additional benefits. The aim of this review is to provide a brief update on the current literature studying the efficacy, safety and significance of the use of Orlistat in clinical practice.Keywords: obese, weight, diet, orlistat, hypertension, cholesterol

  16. Update of the European Landslide Susceptibility Map (ELSUS Version 2)

    Science.gov (United States)

    Wilde, Martina; Günther, Andreas; Malet, Jean-Philippe; Reichenbach, Paola; Hervás, Javier

    2015-04-01

    by ROC curve metrics obtained with the updated landslide inventory. However, the assessment still suffers from missing landslide information in many European terrains. It can be suspected that more distributed landslides information in specific model zones will further enhance the accuracy of ELSUS in the future.

  17. Alternative energies updates on progress

    CERN Document Server

    Ferreira, Germán

    2013-01-01

    This book examines the key pillars of alternative energy, including biomass, hydrogen, solar and geothermal. It features life cycle assessment and thermoeconomic analysis as tools for evaluating and optimising environmental and cost subjects.

  18. Glass Dissolution Parameters: Update for Entsorgungsnachweis

    Energy Technology Data Exchange (ETDEWEB)

    Curti, E

    2003-11-01

    This document provides updated long-term corrosion rates for borosilicate glasses used in Switzerland as a matrix for high-level radioactive waste. The new rates are based on long-term leaching experiments conducted at PSI and are corroborated by recent investigations. The asymptotic rates have been determined through weighted linear regressions of the normalised mass losses, directly calculated from B and Li concentrations in the leaching solutions. Special attention was given to the determination of the analytical uncertainty of the mass losses. The sensitivity of the corrosion rates to analytical uncertainties and to other criteria (e.g. the choice of data points for the regressions) was also studied. A major finding was that the uncertainty of the corrosion rate mainly depends on the uncertainty of the specific glass surface area. The reference rates proposed for safety assessment calculations are 1.5 mg m{sup -2} d{sup -1} for BNFL glasses and 0.2 mg m{sup -2} d{sup -1} for Cogema glasses. The relevance of the proposed corrosion rates for repository conditions is shown based on the analysis of processes and parameters currently known to affect the long-term kinetics of silicate glasses. Specifically, recent studies indicate that potentially detrimental effects, notably the removal of silica from solution through adsorption on clay minerals, are transitory and will not affect the long-term corrosion rate of the Swiss reference glasses. Iron corrosion products are also known to bind silica, but present data are not sufficient to quantify their influence on the long-term rate. (author)

  19. System Oriented Runway Management: A Research Update

    Science.gov (United States)

    Lohr, Gary W.; Brown, Sherilyn A.; Stough, Harry P., III; Eisenhawer, Steve; Atkins, Stephen; Long, Dou

    2011-01-01

    The runway configuration used by an airport has significant implications with respect to its capacity and ability to effectively manage surface and airborne traffic. Aircraft operators rely on runway configuration information because it can significantly affect an airline's operations and planning of their resources. Current practices in runway management are limited by a relatively short time horizon for reliable weather information and little assistance from automation. Wind velocity is the primary consideration when selecting a runway configuration; however when winds are below a defined threshold, discretion may be used to determine the configuration. Other considerations relevant to runway configuration selection include airport operator constraints, weather conditions (other than winds) traffic demand, user preferences, surface congestion, and navigational system outages. The future offers an increasingly complex landscape for the runway management process. Concepts and technologies that hold the potential for capacity and efficiency increases for both operations on the airport surface and in terminal and enroute airspace are currently under investigation. Complementary advances in runway management are required if capacity and efficiency increases in those areas are to be realized. The System Oriented Runway Management (SORM) concept has been developed to address this critical part of the traffic flow process. The SORM concept was developed to address all aspects of runway management for airports of varying sizes and to accommodate a myriad of traffic mixes. SORM, to date, addresses the single airport environment; however, the longer term vision is to incorporate capabilities for multiple airport (Metroplex) operations as well as to accommodate advances in capabilities resulting from ongoing research. This paper provides an update of research supporting the SORM concept including the following: a concept of overview, results of a TRCM simulation, single

  20. Dissociating Working Memory Updating and Automatic Updating: The Reference-Back Paradigm

    Science.gov (United States)

    Rac-Lubashevsky, Rachel; Kessler, Yoav

    2016-01-01

    Working memory (WM) updating is a controlled process through which relevant information in the environment is selected to enter the gate to WM and substitute its contents. We suggest that there is also an automatic form of updating, which influences performance in many tasks and is primarily manifested in reaction time sequential effects. The goal…

  1. Tourette's Disorder: Genetic Update, Neurological Correlates, and Evidence-Based Interventions

    Science.gov (United States)

    Phelps, LeAdelle

    2008-01-01

    This article provides an update of the search for genetic markers related to Tourette's Disorder. The probable neurophysiology of the disorder is reviewed. Frequently prescribed medications are related to the probable biological bases of the disorder. Behavioral interventions and assessment tools are examined. It is concluded that evidence based…

  2. Economic Evaluations of Pharmacogenetic and Pharmacogenomic Screening Tests : A Systematic Review. Second Update of the Literature

    NARCIS (Netherlands)

    Berm, Elizabeth J J; Looff, Margot de; Wilffert, Bob; Boersma, Cornelis; Annemans, Lieven; Vegter, Stefan; van Boven, Job FM; Postma, Maarten J

    2016-01-01

    Objective Due to extended application of pharmacogenetic and pharmacogenomic screening (PGx) tests it is important to assess whether they provide good value for money. This review provides an update of the literature. Methods A literature search was performed in PubMed and papers published between

  3. An update of a national database of low-level radioactive waste in Canada

    Energy Technology Data Exchange (ETDEWEB)

    De, P.L.; Barker, R.C. [Atomic Energy Canada Ltd. Research, Ottawa, Ontario (Canada). Low-Level Radioactive Waste Management Office

    1993-03-01

    This paper gives an overview and update of a national database of low-level radioactive waste in Canada. To provide a relevant perspective, Canadian data are compared with US data on annual waste arisings and with disposal initiatives of the US compacts and states. Presented also is an assessment of the data and its implications for disposal solutions in Canada.

  4. Regression analysis of censored data using pseudo-observations: An update

    DEFF Research Database (Denmark)

    Overgaard, Morten; Andersen, Per Kragh; Parner, Erik Thorlund

    2015-01-01

    competing risks, the restricted mean survival-time function, and the cause-specific lost-lifetime function. The pseudo-observations can be used to assess the effects of covariates on their respective functions at different times by fitting generalized linear models to the pseudo-observations. The updated...

  5. Climate change adaptation impact cost assessment in France. Second phase report. September 2009; Evaluation du cout des impacts du changement climatique et de l'adaptation en France. Rapport de la deuxieme phase. Septembre 2009

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-07-01

    Firstly, this report presents the context and challenges of works dealing with climate change adaptation assessment: observations and perspectives of climate change, concepts and definitions of adaptation to climate change, adaptation within national, European and international context, objectives and organisation of the France's inter-departmental Group. It describes the chosen methodology: hypothesis, methodological tools (climate model), bibliographical tool, and heat wave counting methodology. It discusses the present results, outlines the encountered difficulties and discusses the perspectives for future work

  6. PUMA: The Positional Update and Matching Algorithm

    Science.gov (United States)

    Line, J. L. B.; Webster, R. L.; Pindor, B.; Mitchell, D. A.; Trott, C. M.

    2017-01-01

    We present new software to cross-match low-frequency radio catalogues: the Positional Update and Matching Algorithm. The Positional Update and Matching Algorithm combines a positional Bayesian probabilistic approach with spectral matching criteria, allowing for confusing sources in the matching process. We go on to create a radio sky model using Positional Update and Matching Algorithm based on the Murchison Widefield Array Commissioning Survey, and are able to automatically cross-match 98.5% of sources. Using the characteristics of this sky model, we create simple simulated mock catalogues on which to test the Positional Update and Matching Algorithm, and find that Positional Update and Matching Algorithm can reliably find the correct spectral indices of sources, along with being able to recover ionospheric offsets. Finally, we use this sky model to calibrate and remove foreground sources from simulated interferometric data, generated using OSKAR (the Oxford University visibility generator). We demonstrate that there is a substantial improvement in foreground source removal when using higher frequency and higher resolution source positions, even when correcting positions by an average of 0.3 arcmin given a synthesised beam-width of 2.3 arcmin.

  7. Important update of CERN Mail Services

    CERN Multimedia

    IT Department

    2009-01-01

    The CERN Mail Services are evolving. In the course of June and July 2009, all CERN mailboxes will be updated with a new infrastructure for hosting mailboxes, running Exchange 2007. This update is taking place in order to provide the capacity upgrade for the constantly growing volume of CERN mailboxes. It is also the opportunity to provide a number of improvements to CERN mailboxes: new and improved Outlook Web Access (the web interface used to access your mailbox from a web browser, also known as "webmail"), new features in the Out-of-Office auto-reply assistant, easier spam management... The update will preserve the mailbox configuration and no specific action is required by users. During the next weeks, each mailbox will be individually notified of the upcoming update the day before it takes place. We invite all users to carefully read this notification as it will contain the latest information for this update. The mailbox will be unavailable for a short time during the ni...

  8. Medicare Update: Annual Wellness Visit

    Science.gov (United States)

    ... and nutrition. • Review of the responses to the Health Risk Assessment Prepared by Leslie Fried, Alzheimer’s Association Medicare Advocacy Project. Rev. Feb 1, 2012 The Medicare Advocacy Project is supported by a generous grant by the Eisenberg Family Trust.

  9. Clean Coal Technology Programs: Program Update 2009

    Energy Technology Data Exchange (ETDEWEB)

    None

    2009-10-01

    The purpose of the Clean Coal Technology Programs: Program Update 2009 is to provide an updated status of the U.S. Department of Energy (DOE) commercial-scale demonstrations of clean coal technologies (CCT). These demonstrations have been performed under the Clean Coal Technology Demonstration Program (CCTDP), the Power Plant Improvement Initiative (PPII), and the Clean Coal Power Initiative (CCPI). Program Update 2009 provides: (1) a discussion of the role of clean coal technology demonstrations in improving the nation’s energy security and reliability, while protecting the environment using the nation’s most abundant energy resource—coal; (2) a summary of the funding and costs of the demonstrations; and (3) an overview of the technologies being demonstrated, along with fact sheets for projects that are active, recently completed, or recently discontinued.

  10. A Provenance Tracking Model for Data Updates

    Directory of Open Access Journals (Sweden)

    Gabriel Ciobanu

    2012-08-01

    Full Text Available For data-centric systems, provenance tracking is particularly important when the system is open and decentralised, such as the Web of Linked Data. In this paper, a concise but expressive calculus which models data updates is presented. The calculus is used to provide an operational semantics for a system where data and updates interact concurrently. The operational semantics of the calculus also tracks the provenance of data with respect to updates. This provides a new formal semantics extending provenance diagrams which takes into account the execution of processes in a concurrent setting. Moreover, a sound and complete model for the calculus based on ideals of series-parallel DAGs is provided. The notion of provenance introduced can be used as a subjective indicator of the quality of data in concurrent interacting systems.

  11. Performance Evaluation of Biometric Template Update

    CERN Document Server

    Giot, Romain; Dorizzi, Bernadette

    2012-01-01

    Template update allows to modify the biometric reference of a user while he uses the biometric system. With such kind of mechanism we expect the biometric system uses always an up to date representation of the user, by capturing his intra-class (temporary or permanent) variability. Although several studies exist in the literature, there is no commonly adopted evaluation scheme. This does not ease the comparison of the different systems of the literature. In this paper, we show that using different evaluation procedures can lead in different, and contradictory, interpretations of the results. We use a keystroke dynamics (which is a modality suffering of template ageing quickly) template update system on a dataset consisting of height different sessions to illustrate this point. Even if we do not answer to this problematic, it shows that it is necessary to normalize the template update evaluation procedures.

  12. The neural dynamics of updating person impressions.

    Science.gov (United States)

    Mende-Siedlecki, Peter; Cai, Yang; Todorov, Alexander

    2013-08-01

    Person perception is a dynamic, evolving process. Because other people are an endless source of social information, people need to update their impressions of others based upon new information. We devised an fMRI study to identify brain regions involved in updating impressions. Participants saw faces paired with valenced behavioral information and were asked to form impressions of these individuals. Each face was seen five times in a row, each time with a different behavioral description. Critically, for half of the faces the behaviors were evaluatively consistent, while for the other half they were inconsistent. In line with prior work, dorsomedial prefrontal cortex (dmPFC) was associated with forming impressions of individuals based on behavioral information. More importantly, a whole-brain analysis revealed a network of other regions associated with updating impressions of individuals who exhibited evaluatively inconsistent behaviors, including rostrolateral PFC, superior temporal sulcus, right inferior parietal lobule and posterior cingulate cortex.

  13. Constrained Subjective Assessment of Student Learning

    Science.gov (United States)

    Saliu, Sokol

    2005-09-01

    Student learning is a complex incremental cognitive process; assessment needs to parallel this, reporting the results in similar terms. Application of fuzzy sets and logic to the criterion-referenced assessment of student learning is considered here. The constrained qualitative assessment (CQA) system was designed, and then applied in assessing a past course in microcomputer system design (MSD). CQA criteria were articulated in fuzzy terms and sets, and the assessment procedure was cast as a fuzzy inference rule base. An interactive graphic interface provided for transparent assessment, student "backwash," and support to the teacher when compiling the tests. Grade intervals, obtained from a departmental poll, were used to compile a fuzzy "grade" set. Assessment results were compared to those of a former standard method and to those of a modified version of it (but with fewer criteria). The three methods yielded similar results, supporting the application of CQA. The method improved assessment reliability by means of the consensus embedded in the fuzzy grade set, and improved assessment validity by integrating fuzzy criteria into the assessment procedure.

  14. Indoor Spatial Updating with Reduced Visual Information.

    Directory of Open Access Journals (Sweden)

    Gordon E Legge

    Full Text Available Spatial updating refers to the ability to keep track of position and orientation while moving through an environment. People with impaired vision may be less accurate in spatial updating with adverse consequences for indoor navigation. In this study, we asked how artificial restrictions on visual acuity and field size affect spatial updating, and also judgments of the size of rooms.Normally sighted young adults were tested with artificial restriction of acuity in Mild Blur (Snellen 20/135 and Severe Blur (Snellen 20/900 conditions, and a Narrow Field (8° condition. The subjects estimated the dimensions of seven rectangular rooms with and without these visual restrictions. They were also guided along three-segment paths in the rooms. At the end of each path, they were asked to estimate the distance and direction to the starting location. In Experiment 1, the subjects walked along the path. In Experiment 2, they were pushed in a wheelchair to determine if reduced proprioceptive input would result in poorer spatial updating.With unrestricted vision, mean Weber fractions for room-size estimates were near 20%. Severe Blur but not Mild Blur yielded larger errors in room-size judgments. The Narrow Field was associated with increased error, but less than with Severe Blur. There was no effect of visual restriction on estimates of distance back to the starting location, and only Severe Blur yielded larger errors in the direction estimates. Contrary to expectation, the wheelchair subjects did not exhibit poorer updating performance than the walking subjects, nor did they show greater dependence on visual condition.If our results generalize to people with low vision, severe deficits in acuity or field will adversely affect the ability to judge the size of indoor spaces, but updating of position and orientation may be less affected by visual impairment.

  15. Erythropoietin: physiology and pharmacology update.

    Science.gov (United States)

    Fisher, James W

    2003-01-01

    This minireview is an update of a 1997 review on erythropoietin (EPO) in this journal. EPO is a 30,400-dalton glycoprotein that regulates red cell production. In the human, EPO is produced by peritubular cells in the kidneys of the adult and in hepatocytes in the fetus. Small amounts of extra-renal EPO are produced by the liver in adult human subjects. EPO binds to an erythroid progenitor cell surface receptor that includes a p66 chain, and, when activated, the p66 protein becomes dimerized. EPO receptor activation induces a JAK2 tyrosine kinase, which leads to tyrosine phosphorylation of the EPO receptor and several proteins. EPO receptor binding leads to intracellular activation of the Ras/mitogen-activated kinase pathway, which is involved with cell proliferation, phosphatidylinositol 3-kinase, and STATS 1, 3, 5A, and 5B transcriptional factors. EPO acts primarily to rescue erythroid cells from apoptosis (programmed cell death) to increase their survival. EPO acts synergistically with several growth factors (SCF, GM-CSF, 1L-3, and IGF-1) to cause maturation and proliferation of erythroid progenitor cells (primarily colony-forming unit-E). Oxygen-dependent regulation of EPO gene expression is postulated to be controlled by a hypoxia-inducible transcription factor (HIF-1alpha). Hypoxia-inducible EPO production is controlled by a 50-bp hypoxia-inducible enhancer that is approximately 120 bp 3' to the polyadenylation site. Hypoxia signal transduction pathways involve kinases A and C, phospholipase A(2), and transcription factors ATF-1 and CREB-1. A model has been proposed for adenosine activation of EPO production that involves protein kinases A and C and the phospholipase A(2) pathway. Other effects of EPO include a hematocrit-independent, vasoconstriction-dependent hypertension, increased endothelin production, upregulation of tissue renin, change in vascular tissue prostaglandins production, stimulation of angiogenesis, and stimulation of endothelial and vascular

  16. The effectiveness of updating metacognitive knowledge in the elderly: evidence from metamnemonic judgments of word frequency.

    Science.gov (United States)

    Tullis, Jonathan G; Benjamin, Aaron S

    2012-09-01

    Accurate metacognitive knowledge is vital for optimal performance in self-regulated learning. Yet older adults have deficiencies in implementing effective learning strategies and knowledge updating and consequently may not learn as effectively from task experience as younger adults. Here we assess the ability of older adults to update metacognitive knowledge about the effects of word frequency on recognition. Young adults have been shown to correct their misconceptions through experience with the task, but the greater difficulty older adults have with knowledge updating makes it unclear whether task experience will be sufficient for older adults. The performance of older adults in this experiment qualitatively replicates the results of a comparison group of younger subjects, indicating that both groups are able to correct their metacognitive knowledge through task experience. Older adults seem to possess more effective and flexible metacognition than sometimes suggested.

  17. The teaching of geophysics in Latin America: An updated assessment

    Science.gov (United States)

    Valencio, Daniel A.; Schneider, Otto

    The situation of geophysics in developing countries has been the subject of discussions and analysis by diverse international organizations. It was also discussed in some articles in Eos [e.g., Lomnitz, 1982; Urrutia Fucugauchi, 1982; Bolt, 1982]. We have been requested to contribute a current evaluation of the problem, with particular reference to geophysical education in Latin America.In the following report on specialized training of geophysicists in Latin American countries, we consider the “exact earth sciences” in the broader sense, i.e., the mathematical and physical (and, to a certain extent, chemical) aspects of the planet earth as a whole, including its fluid portions, as opposed to the more restricted concept of just solid earth geophysics. In other words, our inquiry follows the scope of both AGU and the International Union of Geodesy and Geophysics (IUGG), so geodesy, although not explicitly covered, will still be mentioned occasionally. We will also consider the applied branches, especially exploration geophysics, since these areas furnish powerful motivation for fostering our sciences, both in the governmental circles of developing countries and among the young people looking for a promising professional future.

  18. Updated Perspectives on Educational Diagnosticians' Understanding of Reading Assessments

    Science.gov (United States)

    Rueter, Jessica A.; McWhorter, Rochell R.; Lamb, John H.; Dykes, Frank O.

    2016-01-01

    Chappell, Stephens, Kinnison, and Pettigrew (2009) conducted a study investigating educational diagnosticians knowledge of early reading development. Our study replicated the work of Chappell et al. through a mixed methods design that investigated educational diagnosticians' perceptions and knowledge of early reading development. Additionally, our…

  19. Model update and variability assessment for automotive crash simulations

    NARCIS (Netherlands)

    Sun, J.; He, J.; Vlahopoulos, N.; Ast, P. van

    2007-01-01

    In order to develop confidence in numerical models which are used for automotive crash simulations, results are often compared with test data, and in some cases the numerical models are adjusted in order to improve the correlation. Comparisons between the time history of acceleration responses from

  20. Assessing Model Selection Uncertainty Using a Bootstrap Approach: An Update

    NARCIS (Netherlands)

    Lubke, Gitta H.; Campbell, Ian; McArtor, Dan; Miller, Patrick; Luningham, Justin; van den Berg, Stéphanie Martine

    2017-01-01

    Model comparisons in the behavioral sciences often aim at selecting the model that best describes the structure in the population. Model selection is usually based on fit indexes such as Akaike’s information criterion (AIC) or Bayesian information criterion (BIC), and inference is done based on the

  1. Assessing Model Selection Uncertainty Using a Bootstrap Approach: An Update

    NARCIS (Netherlands)

    Lubke, Gitta H.; Campbell, Ian; McArtor, Dan; Miller, Patrick; Luningham, Justin; Berg, van den Stephanie M.

    2016-01-01

    Model comparisons in the behavioral sciences often aim at selecting the model that best describes the structure in the population. Model selection is usually based on fit indexes such as Akaike’s information criterion (AIC) or Bayesian information criterion (BIC), and inference is done based on the

  2. Assessing Model Selection Uncertainty Using a Bootstrap Approach: An Update

    NARCIS (Netherlands)

    Lubke, Gitta H.; Campbell, Ian; McArtor, Dan; Miller, Patrick; Luningham, Justin; Berg, van den Stephanie M.

    2017-01-01

    Model comparisons in the behavioral sciences often aim at selecting the model that best describes the structure in the population. Model selection is usually based on fit indexes such as Akaike’s information criterion (AIC) or Bayesian information criterion (BIC), and inference is done based on the

  3. An assessment by the Statin Intolerance Panel: 2014 update.

    Science.gov (United States)

    Guyton, John R; Bays, Harold E; Grundy, Scott M; Jacobson, Terry A; The National Lipid Association Statin Intolerance Panel

    2014-01-01

    This article from the National Lipid Association Statin Intolerance Panel provides a framework for understanding statin intolerance and makes general recommendations for health professionals. For specific guidance on adverse events related to muscle, liver, cognition, and glucose metabolism, one should refer to the other reports of the Statin Safety Task Force for those topics. Although statin adverse effects rarely lead to permanent sequelae, symptomatic intolerance frequently hinders cardiovascular risk reduction by statins. We emphasize here the advisory role of the clinician helping each patient to make personal decisions on statin tolerability. We identify a pressing need for further research on statin intolerance and make suggestions for research design.

  4. [Health in Mexico: old and rising challenges. An updated assessment].

    Science.gov (United States)

    Narro Robles, José; Zepeda Tena, Carolina

    2012-01-01

    In recent decades, Mexico has come a long way in health care matters, which has influenced the standard of living of the population and the development of the country. However, much remains to be done and changes should happen faster. Some of the main challenges Mexico faces currently are presented in this document and include: the challenge of reducing poverty in order to improve the health status of society; the development of health services that affect the slowdown in the pace of evolution of demographic indicators, life expectancy at birth and infant mortality; the challenge of reducing inequality; the challenge of great infrastructure available in the country for health care and the limited performance obtained in terms of organization, management and financing; the challenge resulting from human resources training systems, both undergraduate and postgraduate; the challenge that relates to academic and scientific productivity; the challenge of diabetes as an example of a serious public health problem; and the challenge of ethical implications in the organization and administration of health services, specifically, the allocation of public resources to them.

  5. Globally coupled maps with asynchronous updating

    CERN Document Server

    Abramson, G; Abramson, Guillermo; Zanette, Damian H.

    1998-01-01

    We analyze a system of globally coupled logistic maps with asynchronous updating. We show that its dynamics differs considerably from that of the synchronous case. For growing values of the coupling intensity, an inverse bifurcation cascade replaces the structure of clusters and ordering in the phase diagram. We present numerical simulations and an analytical description based on an effective single-element dynamics affected by internal fluctuations. Both of them show how global coupling is able to suppress the complexity of the single-element evolution. We find that, in contrast to systems with synchronous update, internal fluctuations satisfy the law of large numbers.

  6. Brucellosis update in Libya and regional prospective.

    Science.gov (United States)

    Ahmed, Mohamed O; Abouzeed, Yousef M; Bennour, Emad M; van Velkinburgh, Jennifer C

    2015-02-01

    Brucellosis is a global bacterial zoonosis responsible for high morbidity in humans and significant livestock economic losses. While brucellosis remains a public health concern worldwide, its global geographic distribution is variable, largely due to different management schemes; however, paucity of information renders the status of brucellosis unclear and incomplete in many countries, especially those with low income and under-developed infrastructure. This short article summarizes and discusses recent important updates on brucellosis from the North African countries, with a particular brief emphasis on the current status and recent updates in Libya.

  7. The Molecular Biology Database Collection: 2008 update.

    Science.gov (United States)

    Galperin, Michael Y

    2008-01-01

    The Nucleic Acids Research online Molecular Biology Database Collection is a public repository that lists more than 1000 databases described in this and previous Nucleic Acids Research annual database issues, as well as a selection of molecular biology databases described in other journals. All databases included in this Collection are freely available to the public. The 2008 update includes 1078 databases, 110 more than the previous one. The links to more than 80 databases have been updated and 25 obsolete databases have been removed from the list. The complete database list and summaries are available online at the Nucleic Acids Research web site, http://nar.oxfordjournals.org/.

  8. Update in clinical allergy and immunology.

    Science.gov (United States)

    von Gunten, S; Marsland, B J; von Garnier, C; Simon, D

    2012-12-01

    In the recent years, a tremendous body of studies has addressed a broad variety of distinct topics in clinical allergy and immunology. In this update, we discuss selected recent data that provide clinically and pathogenetically relevant insights or identify potential novel targets and strategies for therapy. The role of the microbiome in shaping allergic immune responses and molecular, as well as cellular mechanisms of disease, is discussed separately and in the context of atopic dermatitis, as an allergic model disease. Besides summarizing novel evidence, this update highlights current areas of uncertainties and debates that, as we hope, shall stimulate scientific discussions and research activities in the field.

  9. State energy-price system: 1981 update

    Energy Technology Data Exchange (ETDEWEB)

    Fang, J.M.; Imhoff, K.L.; Hood, L.J.

    1983-08-01

    This report updates the State Energy Price Data System (STEPS) to include state-level energy prices by fuel and by end-use sectors for 1981. Both physical unit prices and Btu prices are presented. Basic documentation of the data base remains generally the same as in the original report: State Energy Price System; Volume 1: Overview and Technical Documentation (DOE/NBB-0029 Volume 1 of 2, November 1982). The present report documents only the changes in procedures necessitated by the update to 1981 and the corrections to the basic documentation.

  10. Concepts of incremental updating and versioning

    CSIR Research Space (South Africa)

    Cooper, Antony K

    2004-07-01

    Full Text Available . BACKGROUND TO THE PROBLEM OF INCREMENTAL UPDATING AND VERSIONING As well as a number of Commissions, the International Cartographic Association (ICA) had one Working Group, on Incremental Updating and Versioning, and this presentation describes some... of the work undertaken recently by the Working Group (WG). The WG was voted for a Commission by the General Assembly held at the 21st ICC in Durban, South Africa. The basic problem being addressed by the Commission is that a user compiles their data base...

  11. Soft sensor modelling by time difference, recursive partial least squares and adaptive model updating

    Science.gov (United States)

    Fu, Y.; Yang, W.; Xu, O.; Zhou, L.; Wang, J.

    2017-04-01

    To investigate time-variant and nonlinear characteristics in industrial processes, a soft sensor modelling method based on time difference, moving-window recursive partial least square (PLS) and adaptive model updating is proposed. In this method, time difference values of input and output variables are used as training samples to construct the model, which can reduce the effects of the nonlinear characteristic on modelling accuracy and retain the advantages of recursive PLS algorithm. To solve the high updating frequency of the model, a confidence value is introduced, which can be updated adaptively according to the results of the model performance assessment. Once the confidence value is updated, the model can be updated. The proposed method has been used to predict the 4-carboxy-benz-aldehyde (CBA) content in the purified terephthalic acid (PTA) oxidation reaction process. The results show that the proposed soft sensor modelling method can reduce computation effectively, improve prediction accuracy by making use of process information and reflect the process characteristics accurately.

  12. Updated U.S. population standard for the Veterans RAND 12-item Health Survey (VR-12).

    Science.gov (United States)

    Selim, Alfredo J; Rogers, William; Fleishman, John A; Qian, Shirley X; Fincke, Benjamin G; Rothendler, James A; Kazis, Lewis E

    2009-02-01

    The purpose of this project was to develop an updated U.S. population standard for the Veterans RAND 12-item Health Survey (VR-12). We used a well-defined and nationally representative sample of the U.S. population from 52,425 responses to the Medical Expenditure Panel Survey (MEPS) collected between 2000 and 2002. We applied modified regression estimates to update the non-proprietary 1990 scoring algorithms. We applied the updated standard to the Medicare Health Outcomes Survey (HOS) to compute the VR-12 physical (PCS((MEPS standard))) and mental (MCS((MEPS standard))) component summaries based on the MEPS. We compared these scores to PCS and MCS based on the 1990 U.S. population standard. Using the updated U.S. population standard, the average VR-12 PCS((MEPS standard)) and MCS((MEPS standard)) scores in the Medicare HOS were 39.82 (standard deviation [SD] = 12.2) and 50.08 (SD = 11.4), respectively. For the same Medicare HOS, the average PCS and MCS scores based on the 1990 standard were 1.40 points higher and 0.99 points lower in comparison to VR-12 PCS and MCS, respectively. Changes in the U.S. population between 1990 and today make the old standard obsolete for the VR-12, so the updated standard developed here is widely available to serve as such a contemporary standard for future applications for health-related quality of life (HRQoL) assessments.

  13. Study of Updating Initiating Event Frequency using Prognostics

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hyeonmin; Lee, Sang-Hwan; Park, Jun-seok; Kim, Hyungdae; Chang, Yoon-Suk; Heo, Gyunyoung [Kyung Hee Univ., Yongin (Korea, Republic of)

    2014-10-15

    The Probabilistic Safety Assessment (PSA) model enables to find the relative priority of accident scenarios, weak points in achieving accident prevention or mitigation, and insights to improve those vulnerabilities. Thus, PSA consider realistic calculation for precise and confidence results. However, PSA model still 'conservative' aspects in the procedures of developing a PSA model. One of the sources for the conservatism is caused by the assumption of safety analysis and the estimation of failure frequency. Recently, Surveillance, Diagnosis, and Prognosis (SDP) is a growing trend in applying space and aviation systems in particular. Furthermore, a study dealing with the applicable areas and state-of-the-art status of the SDP in nuclear industry was published. SDP utilizing massive database and information technology among such enabling techniques is worthwhile to be highlighted in terms of the capability of alleviating the conservatism in the conventional PSA. This paper review the concept of integrating PSA and SDP and suggest the updated methodology of Initiating Event (IE) using prognostics. For more detailed, we focus on IE of the Steam Generator Tube Rupture (SGTR) considering tube degradation. This paper is additional research of previous our suggested the research. In this paper, the concept of integrating PSA and SDP are suggested. Prognostics algorithms in SDP are applied at IE, Bes in the Level 1 PSA. As an example, updating SGTR IE and its ageing were considered. Tube ageing were analyzed by using PASTA and Monte Carlo method. After analyzing the tube ageing, conventional SGTR IE were updated by using Bayesian approach. The studied method can help to cover the static and conservatism in PSA.

  14. Updated TDP-43 in Alzheimer's disease staging scheme.

    Science.gov (United States)

    Josephs, Keith A; Murray, Melissa E; Whitwell, Jennifer L; Tosakulwong, Nirubol; Weigand, Stephen D; Petrucelli, Leonard; Liesinger, Amanda M; Petersen, Ronald C; Parisi, Joseph E; Dickson, Dennis W

    2016-04-01

    In this study, we update the TDP-43 in Alzheimer's disease staging scheme by assessing the topography of TDP-43 in 193 cases of Alzheimer's disease, in 14 different brain regions (eight previously described plus six newly reported) and use conditional probability to model the spread of TDP-43 across the 14 brain regions. We show that in addition to the eight original regions we previously reported [amygdala, entorhinal cortex, subiculum, dentate gyrus of the hippocampus, occipitotemporal cortex, inferior temporal cortex, middle frontal cortex and basal ganglia (putamen/globus pallidum)] that TDP-43 is also deposited in the insular cortex, ventral striatum, basal forebrain, substantia nigra, midbrain tectum, and the inferior olive of the medulla oblongata, in Alzheimer's disease. The conditional probability analysis produced six significantly different stages (P TDP-43 deposition begins in the amygdala (stage 1), then moves to entorhinal cortex and subiculum (stage 2); to the dentate gyrus of the hippocampus and occipitotemporal cortex (stage 3); insular cortex, ventral striatum, basal forebrain and inferior temporal cortex (stage 4); substantia nigra, inferior olive and midbrain tectum (stage 5); and finally to basal ganglia and middle frontal cortex (stage 6). This updated staging scheme is superior to our previous staging scheme, classifying 100% of the cases (versus 94% in the old scheme), based on criteria provided, and shows clinical significance with some regions and with increasing stage. We discuss the relevance of the updated staging scheme, as well as its impact on the prion-like hypothesis of protein spread in neurodegenerative disease. We also address the issue of whether frontotemporal lobar degeneration with TDP-43 could be the primary pathology in stage 6.

  15. Silicone Gel-Filled Breast Implants: Updated Safety Information

    Science.gov (United States)

    ... For Consumers Home For Consumers Consumer Updates Silicone Gel-Filled Breast Implants: Updated Safety Information Share Tweet ... When the Food and Drug Administration allowed silicone gel-filled breast implants back on the market in ...

  16. The value of information updating in new product development

    CERN Document Server

    Artmann, Christian

    2009-01-01

    This work shows how managing uncertainty in new product development can be improved by conducting an information update during the development process. The book details the comprehensive model needed to perform that information update.

  17. Sublingual immunotherapy: World Allergy Organization position paper 2013 update

    NARCIS (Netherlands)

    G.W. Canonica (Giorgio Walter); L. Cox (Linda); R. Pawankar (Ruby); C.E. Baena-Cagnani (Carlos); M.S. Blaiss (Michael); S. Bonini (Sergio); J. Bousquet (Jean); M. Calderon (Moises); E. Compalati (Enrico); S.R. Durham (Stephen); R. Gerth van Wijk (Roy); D. Larenas-Linnemann (Désirée); H. Nelson (Harold); G. Passalacqua (Giovanni); O. Pfaar (Oliver); K. Rosario (Karyna); D. Ryan (Dermot); L. Rosenwasser (Lanny); P. Schmid-Grendelmeier (Peter); G.E. Senna (Gianenrico); E. Valovirta (Erkka); H.P. van Bever (Hugo); P. Vichyanond (Pakit); U. Wahn (Ulrich); O.M. Yusuf (Osman)

    2014-01-01

    textabstractWe have prepared this document, "Sublingual Immunotherapy: World Allergy Organization Position Paper 2013 Update", according to the evidence-based criteria, revising and updating chapters of the originally published paper, "Sublingual Immunotherapy: World Allergy Organization Position Pa

  18. Rebuild America partner update, November--December 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-11-01

    This issue of the update includes articles on retrofitting Duke University facilities, energy efficiency updates to buildings in Portland, Oregon, Salisbury, North Carolina, Hawaii, Roanoke-Chowan, Virginia, and energy savings centered designs for lighting systems.

  19. Legislative Update, June 2010. Report 10-13

    Science.gov (United States)

    Blair, Julia

    2010-01-01

    This update contains analyses of legislation being tracked by California Postsecondary Education Commission (CPEC) staff. It has updated positions on bills as adopted in the Commission meeting on June 8. A matrix of bills tracked by CPEC staff is included.

  20. News and Features Updates from USA.gov

    Data.gov (United States)

    General Services Administration — Stay on top of important government news and information with the USA.gov Updates: News and Features RSS feed. We'll update this feed when we add news and featured...