WorldWideScience

Sample records for demonstrated high relative

  1. Generalization of the dispersion relations demonstration; Generalisation de la demonstration des relations de dispersion

    Energy Technology Data Exchange (ETDEWEB)

    Omnes, Roland [Commissariat a l' energie atomique et aux energies alternatives - CEA (France)

    1960-07-01

    A modification of the dispersion relations demonstration for two-particle collisions in field theory is indicated. The direct study of the holomorphy domain of the reaction amplitude, without any reference to a particular coordinate system, allows to demonstrate the dispersion relations with fixed pulse transfer for any input and output particle mass. Reprint of a paper published in Comptes rendus des seances de l'Academie des Sciences, t. 250, p. 1203-1205, sitting of 15 February 1960 [French] On indique une modification de la demonstration des relations de dispersion pour les collisions a deux particules en theorie des champs. En etudiant directement le domaine d'holomorphie de l'amplitude de reaction sans se referer a un systeme de coordonnees particulier, on demontre les relations de dispersion a transfert d'impulsion fixe dans le cas ou les masses des particules entrantes et sortantes sont quelconques. Reproduction d'un article publie dans les Comptes rendus des seances de l'Academie des Sciences, t. 250, p. 1203-1205, seance du 15 fevrier 1960.

  2. The demonstration of the auditory ossicles by high resolution CT

    International Nuclear Information System (INIS)

    Lloyd, G.A.S.; Boulay, G.H. du; Phelps, P.D.; Pullicino, P.

    1979-01-01

    The high resolution CT scanning system introduced by EMI in 1978 has added a new dimension to computerised tomography in otology. The apparatus used for this study was an EMI CT 5005 body scanner adapted for head and neck scanning and incorporating a high resolution facility. The latter has proved most advantageous in areas of relatively high differential absorption, so that its application to the demonstration of abnormalities in the petrous temporal bone, and in particular middle ear disease, has been very rewarding. Traumatic ossicular disruptions may now be demonstrated and the high contrast of CT often shows them better than conventional hypocycloidal tomography. The stapes is also better visualised and congenital abnormalities of its superstructure have been recorded. These studies have been achieved with a very acceptable level of radiation to the eye, lens and cornea and the technique is clearly a rival to conventional pluridirectional tomography in the assessment of the petrous temporal bone. With further design improvements high resolution CT could completely replace existing techniques. (orig.) [de

  3. On the analytical demonstration of Planck-Einstein relation

    OpenAIRE

    Molina Morales, Eddy Luis

    2016-01-01

    In this paper a possible analytical demonstration of Planck's Law for the spectral distribution of the electromagnetic energy radiated by hot bodies is presented, but in this case, the solutions of Maxwell's equations for the electromagnetic radiation problem of Hertz’s dipole are used. The concepts of quantum energy and of photon are redefined from the classical point of view, relating them to the possible electronic nature of electromagnetic waves and the electromagnetic field in general. B...

  4. A Cross-Sectional Study Demonstrating Increased Serum Amyloid A Related Inflammation in High-Density Lipoproteins from Subjects with Type 1 Diabetes Mellitus and How This Association Was Augmented by Poor Glycaemic Control

    Directory of Open Access Journals (Sweden)

    Jane McEneny

    2015-01-01

    Full Text Available Inflammatory atherosclerosis is increased in subjects with type 1 diabetes mellitus (T1DM. Normally high-density lipoproteins (HDL protect against atherosclerosis; however, in the presence of serum amyloid-A- (SAA- related inflammation this property may be reduced. Fasting blood was obtained from fifty subjects with T1DM, together with fifty age, gender and BMI matched control subjects. HDL was subfractionated into HDL2 and HDL3 by rapid ultracentrifugation. Serum-hsCRP and serum-, HDL2-, and HDL3-SAA were measured by ELISAs. Compared to control subjects, SAA was increased in T1DM subjects, nonsignificantly in serum (P=0.088, and significantly in HDL2(P=0.003 and HDL3(P=0.005. When the T1DM group were separated according to mean HbA1c (8.34%, serum-SAA and HDL3-SAA levels were higher in the T1DM subjects with HbA1c ≥ 8.34%, compared to when HbA1c was 0.05. This cross-sectional study demonstrated increased SAA-related inflammation in subjects with T1DM that was augmented by poor glycaemic control. We suggest that SAA is a useful inflammatory biomarker in T1DM, which may contribute to their increased atherosclerosis risk.

  5. Hardware demonstration of high-speed networks for satellite applications.

    Energy Technology Data Exchange (ETDEWEB)

    Donaldson, Jonathon W.; Lee, David S.

    2008-09-01

    This report documents the implementation results of a hardware demonstration utilizing the Serial RapidIO{trademark} and SpaceWire protocols that was funded by Sandia National Laboratories (SNL's) Laboratory Directed Research and Development (LDRD) office. This demonstration was one of the activities in the Modeling and Design of High-Speed Networks for Satellite Applications LDRD. This effort has demonstrated the transport of application layer packets across both RapidIO and SpaceWire networks to a common downlink destination using small topologies comprised of commercial-off-the-shelf and custom devices. The RapidFET and NEX-SRIO debug and verification tools were instrumental in the successful implementation of the RapidIO hardware demonstration. The SpaceWire hardware demonstration successfully demonstrated the transfer and routing of application data packets between multiple nodes and also was able reprogram remote nodes using configuration bitfiles transmitted over the network, a key feature proposed in node-based architectures (NBAs). Although a much larger network (at least 18 to 27 nodes) would be required to fully verify the design for use in a real-world application, this demonstration has shown that both RapidIO and SpaceWire are capable of routing application packets across a network to a common downlink node, illustrating their potential use in real-world NBAs.

  6. Demonstration of deterministic and high fidelity squeezing of quantum information

    DEFF Research Database (Denmark)

    Yoshikawa, J-I.; Hayashi, T-; Akiyama, T.

    2007-01-01

    , and an ancillary squeezed vacuum state, thus direct interaction between a strong pump and the quantum state is circumvented. We demonstrate three different squeezing levels for a coherent state input. This scheme is highly suitable for the fault-tolerant squeezing transformation in a continuous variable quantum...... computer....

  7. High Input Voltage, Silicon Carbide Power Processing Unit Performance Demonstration

    Science.gov (United States)

    Bozak, Karin E.; Pinero, Luis R.; Scheidegger, Robert J.; Aulisio, Michael V.; Gonzalez, Marcelo C.; Birchenough, Arthur G.

    2015-01-01

    A silicon carbide brassboard power processing unit has been developed by the NASA Glenn Research Center in Cleveland, Ohio. The power processing unit operates from two sources: a nominal 300 Volt high voltage input bus and a nominal 28 Volt low voltage input bus. The design of the power processing unit includes four low voltage, low power auxiliary supplies, and two parallel 7.5 kilowatt (kW) discharge power supplies that are capable of providing up to 15 kilowatts of total power at 300 to 500 Volts (V) to the thruster. Additionally, the unit contains a housekeeping supply, high voltage input filter, low voltage input filter, and master control board, such that the complete brassboard unit is capable of operating a 12.5 kilowatt Hall effect thruster. The performance of the unit was characterized under both ambient and thermal vacuum test conditions, and the results demonstrate exceptional performance with full power efficiencies exceeding 97%. The unit was also tested with a 12.5kW Hall effect thruster to verify compatibility and output filter specifications. With space-qualified silicon carbide or similar high voltage, high efficiency power devices, this would provide a design solution to address the need for high power electric propulsion systems.

  8. Low Temperature Combustion Demonstrator for High Efficiency Clean Combustion

    Energy Technology Data Exchange (ETDEWEB)

    Ojeda, William de

    2010-07-31

    The project which extended from November 2005 to May of 2010 demonstrated the application of Low Temperature Combustion (LTC) with engine out NOx levels of 0.2 g/bhp-hr throughout the program target load of 12.6bar BMEP. The project showed that the range of loads could be extended to 16.5bar BMEP, therefore matching the reference lug line of the base 2007 MY Navistar 6.4L V8 engine. Results showed that the application of LTC provided a dramatic improvement over engine out emissions when compared to the base engine. Furthermore LTC improved thermal efficiency by over 5% from the base production engine when using the steady state 13 mode composite test as a benchmark. The key enablers included improvements in the air, fuel injection, and cooling systems made in Phases I and II. The outcome was the product of a careful integration of each component under an intelligent control system. The engine hardware provided the conditions to support LTC and the controller provided the necessary robustness for a stable combustion. Phase III provided a detailed account on the injection strategy used to meet the high load requirements. During this phase, the control strategy was implemented in a production automotive grade ECU to perform cycle-by-cycle combustion feedback on each of the engine cylinders. The control interacted on a cycle base with the injection system and with the Turbo-EGR systems according to their respective time constants. The result was a unique system that could, first, help optimize the combustion system and maintain high efficiency, and secondly, extend the steady state results to the transient mode of operation. The engine was upgraded in Phase IV with a Variable Valve Actuation system and a hybrid EGR loop. The impact of the more versatile EGR loop did not provide significant advantages, however the application of VVA proved to be an enabler to further extend the operation of LTC and gain considerable benefits in fuel economy and soot reduction. Finally

  9. R and D toward highly repetitive laser fusion demonstration

    International Nuclear Information System (INIS)

    Satoh, Nakahiro; Matsukado, Koji; Watari, Takeshi; Sekine, Takashi; Takeuchi, Yasuki; Kawashima, Toshiyuki

    2017-01-01

    Hamamatsu Photonics conducts research on a unique continuous neutron generation method by integrating and utilizing elemental technologies such as laser, target, and measurement for laser nuclear fusion research. In addition, in collaboration with the Graduate School for the Creation of New Photonics Industries, Toyota Motor Corporation, and others, it is conducting research on laser fusion. As a high power laser of element technology, it constructed an ultrahigh intensity laser system by combining glass slab laser KURE-I and ultrahigh intensity femtosecond laser MATSU-I equipped with titanium sapphire transmitter, and achieved a peak output of 20 TW, It plans to further increase this to 100 TW. As other element technologies, it is also considering nuclear fusion fuel - target technology and light - high energy particle measurement technology. Regarding the demonstration of continuous generation of laser fusion neutrons, it performed 100 times of continuous laser beam irradiation at 1 Hz, and actually measured the number of neutrons generated. It measured 4.5x10 4 pieces of neutrons on average (maximum 10 5 ) with a frequency of 98%. Since 100% of neutron generation should occur in principle, in the future it will be necessary to enhancing laser collecting intensity and to improve solid particle number density in order to put this process into practical use as a neutron source. (A.O.)

  10. Prototype high voltage bushing: Configuration to its operational demonstration

    Energy Technology Data Exchange (ETDEWEB)

    Shah, Sejal, E-mail: sshah@iter-india.org [ITER-India, Institute for Plasma Research, Bhat, Gandhinagar 382428 (India); Sharma, D. [Institute for Plasma Research, Bhat, Gandhinagar 382428 (India); Parmar, D.; Tyagi, H.; Joshi, K.; Shishangiya, H.; Bandyopadhyay, M.; Rotti, C.; Chakraborty, A. [ITER-India, Institute for Plasma Research, Bhat, Gandhinagar 382428 (India)

    2016-12-15

    High Voltage Bushing (HVB) is the key component of Diagnostic Neutral Beam (DNB) system of ITER as it provides access to high voltage electrical, hydraulic, gas and diagnostic feedlines to the beam source with isolation from grounded vessel. HVB also provides primary vacuum confinement for the DNB system. Being Safety Important Class (SIC) component of ITER, it involves several configurational, technological and operational challenges. To ensure its operational performance & reliability, particularly electrostatic behavior, half scale down Prototype High Voltage Bushing (PHVB) is designed considering same design criteria of DNB HVB. Design optimization has been carried out followed by finite element (FE) analysis to obtain DNB HVB equivalent electric stress on different parts of PHVB, taking into account all design, manufacturing & space constraints. PHVB was tested up to 60 kV without breakdown, which validates its design for the envisaged operation of 50 kV DC. This paper presents the design of PHVB, FEA validation, manufacturing constraints, experimental layout with interfacing auxiliary systems and operational results related to functional performance.

  11. High-resolution magnetic resonance of the extracranial facial nerve and parotid duct: demonstration of the branches of the intraparotid facial nerve and its relation to parotid tumours by MRI with a surface coil

    International Nuclear Information System (INIS)

    Takahashi, N.; Okamoto, K.; Ohkubo, M.; Kawana, M.

    2005-01-01

    AIM: To investigate the usefulness of high-resolution MR imaging in the evaluation of the extracranial facial nerve, compared with surgical findings. MATERIALS AND METHODS: Thirteen patients with benign parotid tumours were studied on a 1.5-T MR system with a 3 in circular surface coil. High-resolution T1-weighted spin-echo, T2-weighted fast spin-echo, and three-dimensional gradient-recalled acquisition in the steady state (GRASS) images were obtained in the axial planes. Oblique reformatted images were generated. Tumours, parotid ducts and facial nerves were identified on these images. The relationship of the tumours to the facial nerves was confirmed at surgery. RESULTS: Facial nerves appeared as linear structures of low intensity on all pulse sequences. The main trunks and cervicofacial and temporofacial divisions of the facial nerves were identified in 100%, 84.1% and 53.8% of GRASS images, respectively. Parotid ducts appeared as structures of low intensity on T1-weighted (66.6%) and GRASS images (81.8%), and as structures of very high intensity on T2-weighted images (91.7%). The relationships of the tumours to the facial nerves were correctly diagnosed in 11 (91.7%) of 12 cases. CONCLUSION: High-resolution MR imaging depicts the extracranial facial nerve and the parotid duct, and is useful for preoperative evaluation of parotid gland tumours

  12. High-resolution magnetic resonance of the extracranial facial nerve and parotid duct: demonstration of the branches of the intraparotid facial nerve and its relation to parotid tumours by MRI with a surface coil

    Energy Technology Data Exchange (ETDEWEB)

    Takahashi, N. [Department of Radiology, Niigata University Faculty of Medicine, Niigata (Japan) and Department of Radiology, Niigata City General Hospital, Niigata (Japan)]. E-mail: nandtr@hosp.niigata.niigata.jp; Okamoto, K. [Department of Radiology, Niigata University Faculty of Medicine, Niigata (Japan); Ohkubo, M. [Department of Radiotechnology, Niigata University Faculty of Medicine, Niigata (Japan); Kawana, M. [Department of Otorhinolaryngology, Niigata University Faculty of Medicine, Niigata (Japan)

    2005-03-01

    AIM: To investigate the usefulness of high-resolution MR imaging in the evaluation of the extracranial facial nerve, compared with surgical findings. MATERIALS AND METHODS: Thirteen patients with benign parotid tumours were studied on a 1.5-T MR system with a 3 in circular surface coil. High-resolution T1-weighted spin-echo, T2-weighted fast spin-echo, and three-dimensional gradient-recalled acquisition in the steady state (GRASS) images were obtained in the axial planes. Oblique reformatted images were generated. Tumours, parotid ducts and facial nerves were identified on these images. The relationship of the tumours to the facial nerves was confirmed at surgery. RESULTS: Facial nerves appeared as linear structures of low intensity on all pulse sequences. The main trunks and cervicofacial and temporofacial divisions of the facial nerves were identified in 100%, 84.1% and 53.8% of GRASS images, respectively. Parotid ducts appeared as structures of low intensity on T1-weighted (66.6%) and GRASS images (81.8%), and as structures of very high intensity on T2-weighted images (91.7%). The relationships of the tumours to the facial nerves were correctly diagnosed in 11 (91.7%) of 12 cases. CONCLUSION: High-resolution MR imaging depicts the extracranial facial nerve and the parotid duct, and is useful for preoperative evaluation of parotid gland tumours.

  13. West Valley Demonstration Project community relations plan FY 1990/91

    International Nuclear Information System (INIS)

    Damerow, M.W.

    1989-09-01

    The purpose of the Community Relations Plan is to fully inform the community about the West Valley Demonstration Project (WVDP) and provide opportunities for public input. A sound approach to community relations is essential to the creation and maintenance of public awareness and community support. The WVDP is a matter of considerable public interest because it deals with nuclear waste. The mission of the WVDP is to solve an existing environmental concern by solidifying high-level radioactive waste and transporting the solidified waste to a federal repository for permanent disposal. The public requires evidence of the continued commitment and demonstrated progress of the industry and government in carrying out the mission in order to sustain confidence that the WVDP is being managed well and will be discussed successfully completed. For this reason, a comprehensive communication plan is essential for the successful completion of the WVDP

  14. Optical Verification Laboratory Demonstration System for High Security Identification Cards

    Science.gov (United States)

    Javidi, Bahram

    1997-01-01

    Document fraud including unauthorized duplication of identification cards and credit cards is a serious problem facing the government, banks, businesses, and consumers. In addition, counterfeit products such as computer chips, and compact discs, are arriving on our shores in great numbers. With the rapid advances in computers, CCD technology, image processing hardware and software, printers, scanners, and copiers, it is becoming increasingly easy to reproduce pictures, logos, symbols, paper currency, or patterns. These problems have stimulated an interest in research, development and publications in security technology. Some ID cards, credit cards and passports currently use holograms as a security measure to thwart copying. The holograms are inspected by the human eye. In theory, the hologram cannot be reproduced by an unauthorized person using commercially-available optical components; in practice, however, technology has advanced to the point where the holographic image can be acquired from a credit card-photographed or captured with by a CCD camera-and a new hologram synthesized using commercially-available optical components or hologram-producing equipment. Therefore, a pattern that can be read by a conventional light source and a CCD camera can be reproduced. An optical security and anti-copying device that provides significant security improvements over existing security technology was demonstrated. The system can be applied for security verification of credit cards, passports, and other IDs so that they cannot easily be reproduced. We have used a new scheme of complex phase/amplitude patterns that cannot be seen and cannot be copied by an intensity-sensitive detector such as a CCD camera. A random phase mask is bonded to a primary identification pattern which could also be phase encoded. The pattern could be a fingerprint, a picture of a face, or a signature. The proposed optical processing device is designed to identify both the random phase mask and the

  15. Quantified safety objectives in high technology: Meaning and demonstration

    International Nuclear Information System (INIS)

    Vinck, W.F.; Gilby, E.; Chicken, J.

    1986-01-01

    An overview and trends-analysis is given of the types of quantified criteria and objectives which are presently applied or envisaged and discussed in Europe in the nuclear application, more specifically Nuclear Power Plants (NPPs), and in non-nuclear applications, more specifically in the chemical and petrochemical process industry. Some comparative deductions are made. Attention is paid to the similarities or discrepancies between such criteria and objectives and to problems associated with the demonstration that they are implemented. The role of cost-effectiveness of Risk deduction is briefly discussed and mention made of a search made into combining the technical, economic and socio-political factors playing a role in Risk acceptance

  16. An emergency management demonstrator using the high level architecture

    International Nuclear Information System (INIS)

    Williams, R.J.

    1996-12-01

    This paper addresses the issues of simulation interoperability within the emergency management training context. A prototype implementation in Java of a subset of the High Level Architecture (HLA) is described. The use of Web Browsers to provide graphical user interfaces to HLA is also investigated. (au)

  17. Demonstration test for transporting vitrified high-level radioactive wastes

    International Nuclear Information System (INIS)

    Ito, C.; Kato, Y.; Kato, O.

    1993-01-01

    The purpose of this study was to demonstrate the integrity of the cask against a 0.3-m free-drop test and to confirm the drop-test analytical method. 1. Test cask; The cask used in the drop test is characterized structurally as follows. (1) The Cask body is covered with a neutron absorber covered with a thin steel plate. Fins are attached between the cask body and thin steel plate. (2) The impact energy was absorbed mainly by the inelastic deformation of the neutron absorber and thin steel plate. 2. Test methods; Electric heaters were put into the package to reproduce the real cask conditions. Strains and accelerations due to the drop were measured at the drop by the strain gauges and accelerometers attached on the cask. 3. Analysis; We use the DYNA-3D and NIKE-2D codes to analyze the drop test. A half symmetrical model was applied to overall analysis to calculate the strains and accelerations at the cask body. The maximum acceleration value obtained by the overall analysis and basket model were used to statistically calculate the strains at the basket. 4. Results; The cask integrity was comfirmed through the strains and the results of He leak test. (author)

  18. Bioindicator demonstrates high persistence of sulfentrazone in dry soil

    Directory of Open Access Journals (Sweden)

    Renato Coradello Lourenço

    2015-09-01

    Full Text Available In sugarcane crop areas, the application of preemergence herbicides with long residual effect in the soil has been frequently necessary. The herbicide persistence in the soil must be high especially because of applications during the dry season of the year, after sugarcane harvest. This study aimed at estimating the sulfentrazone persistence and dissipation in dry soil using bioindicator. Five experiments were carried out, divided into two phases. In the first phase, three dose-response curves were adjusted to select the best bioindicator to be adopted in the second phase. Niger was adopted due to its lower sensibility to sulfentrazone. In the second phase, a new dose-response curve was carried out, with six doses of sulfentrazone, in order to standardize the bioindicator sensibility to sulfentrazone. At the end, another experiment with six periods of sulfentrazone persistence in dry clay soil was developed. Persistence periods were: 182, 154, 125, 98 and 30 days. The bioindicator was seeded at the application day in treated plots and control. In this experiment, the sulfentrazone dose applied was 800 g ha-1. Niger was considered a good species to estimate the sulfentrazone persistence in dry soil. The sulfentrazone phytotoxic activity was identified up to 182 days after application, and its average dissipation rate was 2.15 g ha-1 day-1, with half-life higher than 182 days.

  19. Fabrication and demonstration of high energy density lithium ion microbatteries

    Science.gov (United States)

    Sun, Ke

    Since their commercialization by Sony two decades ago, Li-ion batteries have only experienced mild improvement in energy and power performance, which remains one of the main hurdles for their widespread implementation in applications outside of powering compact portable devices, such as in electric vehicles. Li-ion batteries must be advanced through a disruptive technological development or a series of incremental improvements in chemistry and design in order to be competitive enough for advanced applications. As it will be introduced in this work, achieving this goal by new chemistries and chemical modifications does not seem to be promising in the short term, so efforts to fully optimize existing systems must be pursued at in parallel. This optimization must be mainly relying on the modification and optimizations of micro and macro structures of current battery systems. This kind of battery architecture study will be even more important when small energy storage devices are desired to power miniaturized and autonomous gadgets, such as MEMs, micro-robots, biomedical sensors, etc. In this regime, the limited space available makes requirements on electrode architecture more stringent and the assembly process more challenging. Therefore, the study of battery assembly strategies for Li-ion microbatteries will benefit not only micro-devices but also the development of more powerful and energetic large scale battery systems based on available chemistries. In chapter 2, preliminary research related to the mechanism for the improved rate capability of cathodes by amorphous lithium phosphate surficial films will be used to motivate the potential for structural optimization of existing commercial lithium ion battery electrode. In the following chapters, novel battery assembly techniques will be explored to achieve new battery architectures. In chapter 3, direct ink writing will be used to fabricate 3D interdigitated microbattery structures that have superior areal energy

  20. Long-term management of high-level radioactive waste. The meaning of a demonstration

    International Nuclear Information System (INIS)

    1983-01-01

    The ''demonstration'' of the safe management of high level radioactive waste is a prerequisite for the further development of nuclear energy. It is therefore essential to be clear about both the meaning of the term ''demonstration'' and the practical means to satisfy this request. In the complex sequence of operations necessary to the safe management of high level waste, short term activities can be directly demonstrated. For longer term activities, such as the long term isolation of radioactive waste in deep undergroung structures, demonstration must be indirect. The ''demonstration'' of deep underground disposal for high level radioactive waste involves two steps: one direct, to prove that the system could be built, operated and closed safely and at acceptable costs, and one indirect, to make a convincing evaluation of the system's performance and long term safety on the basis of predictive analyses confirmed by a body of varied technical and scienfic data, much of it deriving from experimental work. The assessment of the evidence collected from current operations, existing experience in related fields and specific research and development activities, calls for specialized scientific expertise. Uncertainties in far future situations and probabilistic events can be taken into account in a scientific assessment. Competent national authorithies will have to satisfy themselves that the proposed waste management solutions can meet long term safety objectives. An element of judgement will always be needed in determining the acceptability of a waste disposal concept. However, the level of confidence in our ability to predict the performance of waste management systems will increase as supporting evidence is collected from current research and development activities and as our predictive techniques improve

  1. Demonstration of a High Open-Circuit Voltage GaN Betavoltaic Microbattery

    International Nuclear Information System (INIS)

    Cheng Zai-Jun; San Hai-Sheng; Chen Xu-Yuan; Liu Bo; Feng Zhi-Hong

    2011-01-01

    A high open-circuit voltage betavoltaic microbattery based on a GaN p-i-n diode is demonstrated. Under the irradiation of a 4×4 mm 2 planar solid 63 Ni source with an activity of 2 mCi, the open-circuit voltage V oc of the fabricated single 2×2mm 2 cell reaches as high as 1.62 V, the short-circuit current density J sc is measured to be 16nA/cm 2 . The microbattery has a fill factor of 55%, and the energy conversion efficiency of beta radiation into electricity reaches to 1.13%. The results suggest that GaN is a highly promising potential candidate for long-life betavoltaic microbatteries used as power supplies for microelectromechanical system devices. (cross-disciplinary physics and related areas of science and technology)

  2. Japanese HTTR program for demonstration of high temperature applications of nuclear energy

    International Nuclear Information System (INIS)

    Nishihara, T.; Hada, K.; Shiozawa, S.

    1997-01-01

    Construction works of the HTTR started in March 1991 in order to establish and upgrade the HTGR technology basis, to carry out innovative basic researches on high temperature engineering and to demonstrate high temperature heat utilization and application of nuclear heat. This report describes the demonstration program of high temperature heat utilization and application. (author). 2 refs, 4 figs, 3 tabs

  3. Surprise responses in the human brain demonstrate statistical learning under high concurrent cognitive demand

    Science.gov (United States)

    Garrido, Marta Isabel; Teng, Chee Leong James; Taylor, Jeremy Alexander; Rowe, Elise Genevieve; Mattingley, Jason Brett

    2016-06-01

    The ability to learn about regularities in the environment and to make predictions about future events is fundamental for adaptive behaviour. We have previously shown that people can implicitly encode statistical regularities and detect violations therein, as reflected in neuronal responses to unpredictable events that carry a unique prediction error signature. In the real world, however, learning about regularities will often occur in the context of competing cognitive demands. Here we asked whether learning of statistical regularities is modulated by concurrent cognitive load. We compared electroencephalographic metrics associated with responses to pure-tone sounds with frequencies sampled from narrow or wide Gaussian distributions. We showed that outliers evoked a larger response than those in the centre of the stimulus distribution (i.e., an effect of surprise) and that this difference was greater for physically identical outliers in the narrow than in the broad distribution. These results demonstrate an early neurophysiological marker of the brain's ability to implicitly encode complex statistical structure in the environment. Moreover, we manipulated concurrent cognitive load by having participants perform a visual working memory task while listening to these streams of sounds. We again observed greater prediction error responses in the narrower distribution under both low and high cognitive load. Furthermore, there was no reliable reduction in prediction error magnitude under high-relative to low-cognitive load. Our findings suggest that statistical learning is not a capacity limited process, and that it proceeds automatically even when cognitive resources are taxed by concurrent demands.

  4. Demonstration of sulfur solubility determinations in high waste loading, low-activity waste glasses

    Energy Technology Data Exchange (ETDEWEB)

    Fox, K. M. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2016-04-25

    A method recommended by Pacific Northwest National Laboratory (PNNL) for sulfate solubility determinations in simulated low-activity waste glasses was demonstrated using three compositions from a recent Hanford high waste loading glass study. Sodium and sulfate concentrations in the glasses increased after each re-melting step. Visual observations of the glasses during the re-melting process reflected the changes in composition. The measured compositions showed that the glasses met the targeted values. The amount of SO3 retained in the glasses after washing was relatively high, ranging from 1.6 to 2.6 weight percent (wt %). Measured SnO2 concentrations were notably low in all of the study glasses. The composition of the wash solutions should be measured in future work to determine whether SnO2 is present with the excess sulfate washed from the glass. Increases in batch size and the amount of sodium sulfate added did not have a measureable impact on the amount of sulfate retained in the glass, although this was tested for only a single glass composition. A batch size of 250 g and a sodium sulfate addition targeting 7 wt %, as recommended by PNNL, will be used in future experiments.

  5. Demonstration of Caustic-Side Solvent Extraction with Savannah River Site High Level Waste

    International Nuclear Information System (INIS)

    Walker, D.D.

    2001-01-01

    Researchers successfully demonstrated the chemistry and process equipment of the Caustic-Side Solvent Extraction (CSSX) flowsheet for the decontamination of high level waste using a 33-stage, 2-cm centrifugal contactor apparatus at the Savannah River Technology Center. This represents the first CSSX process demonstration using Savannah River Site (SRS) high level waste. Three tests lasting 6, 12, and 48 hours processed simulated average SRS waste, simulated Tank 37H/44F composite waste, and Tank 37H/44F high level waste, respectively

  6. What leadership behaviors were demonstrated by the principal in a high poverty, high achieving elementary school?

    Directory of Open Access Journals (Sweden)

    E. Hayet J. Woods

    2016-12-01

    Full Text Available Examined through the lens of leadership, were the behaviors of a principal as perceived by stakeholders. The following themes emerged: (1 Educating the Whole Child, with the subthemes: (a providing basic needs; (b academic interventions based on achievement data; (c an emphasis on reading; (d extended academic time; and (e relationships; and (2 Synergy of Expectations, with the subthemes: (a consistent student expectations; (b increased staff accountability; and (c community involvement. The researchers found that the principal by demonstrating behaviors as a change agent, a creator of vision, and a provider of necessary support and strategies, rather than adopting numerous programs, the school personnel were able to increase and sustain academic achievement of the students of poverty as well as their peers. Implications for principal practices, along with leadership preparatory programs are significant.

  7. Agreement between children and parents demonstrated that illness-related absenteeism was validly reported by children

    DEFF Research Database (Denmark)

    Denbæk, Anne Maj; Bonnesen, Camilla Thørring; Andersen, Anette

    2016-01-01

    OBJECTIVES: To examine the agreement between children's and parents' reporting of illness-related absenteeism from school and to examine predictors for disagreement between children and parents. STUDY DESIGN AND SETTING: A total of 8,438 schoolchildren aged from 5 to 15 years (grade 0-8) and one...... of 22 weeks. Text messages and questionnaire data were linked at the individual level, leaving 2,269 child-parent pairs in the analysis, corresponding to 27% of the eligible sample. RESULTS: The agreement between children's and parents' reports of illness-related absenteeism was good, with high absolute...... agreement and slight to moderate Ƙ values. Agreement was lowest for 6- to 8-year-olds and highest for 11- to 12-year-olds. Children's reports of illness symptoms and parents' reports of their children's illnesses in the preceding week were strong predictors for children reporting illness-related absenteeism...

  8. DEMONSTRATION BULLETIN: HIGH VOLTAGE ELECTRON BEAM TECHNOLOGY - HIGH VOLTAGE ENVIRONMENTAL APPLICATIONS, INC.

    Science.gov (United States)

    The high energy electron beam irradiation technology is a low temperature method for destroying complex mixtures of hazardous organic chemicals in solutions containing solids. The system consists of a computer-automated, portable electron beam accelerator and a delivery system. T...

  9. Analogue demonstration of a high temperature superconducting sigma-delta modulator with 27 GHz sampling

    Energy Technology Data Exchange (ETDEWEB)

    Forrester, M.G.; Hunt, B.D.; Miller, D.L.; Talvacchio, J.; Young, R.M. [Northrop Grumman Science and Technology Center, Pittsburgh, PA 15235-5098 (United States)

    1999-11-01

    We have successfully fabricated and tested a high temperature superconducting (HTS) sigma-delta modulator for analogue-to-digital conversion. This is the first demonstration of a GHz sampling A-to-D in HTS. The 15-junction single-flux-quantum (SFQ) circuit, fabricated using an epitaxial multilayer HTS process with YBCO/Co-YBCO/YBCO edge junctions, was internally clocked at 27 GHz and used to convert a 5.01 MHz signal. The modulator demonstrated a spur-free dynamic range of more than 75 dB. Two-tone measurements with 5.01 MHz and 5.51 MHz signals demonstrated third-order intermodulation products to be lower than -59 dBc. Demonstration of a functional HTS modulator represents a significant milestone in the development of high dynamic range ADCs suitable for such applications as surveillance radar. (author)

  10. Agreement between children and parents demonstrated that illness-related absenteeism was validly reported by children.

    Science.gov (United States)

    Denbæk, Anne Maj; Bonnesen, Camilla Thørring; Andersen, Anette; Holstein, Bjørn Evald; Laursen, Bjarne; Due, Pernille; Johansen, Anette

    2016-01-01

    To examine the agreement between children's and parents' reporting of illness-related absenteeism from school and to examine predictors for disagreement between children and parents. A total of 8,438 schoolchildren aged from 5 to 15 years (grade 0-8) and one parent of each child were invited to participate in the Hi Five baseline study. The response rate for children answering a questionnaire was 89% (n = 7,525), and 36% of the parents (n = 3,008) participated in a weekly illness registration study using text messages (short message service) over a period of 22 weeks. Text messages and questionnaire data were linked at the individual level, leaving 2,269 child-parent pairs in the analysis, corresponding to 27% of the eligible sample. The agreement between children's and parents' reports of illness-related absenteeism was good, with high absolute agreement and slight to moderate Ƙ values. Agreement was lowest for 6- to 8-year-olds and highest for 11- to 12-year-olds. Children's reports of illness symptoms and parents' reports of their children's illnesses in the preceding week were strong predictors for children reporting illness-related absenteeism when parents did not. Illness-related absenteeism can be reported by children, and children report higher prevalence of illness-related absenteeism than parents. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. Demonstration of a Fiber Optic Regression Probe in a High-Temperature Flow

    Science.gov (United States)

    Korman, Valentin; Polzin, Kurt

    2011-01-01

    The capability to provide localized, real-time monitoring of material regression rates in various applications has the potential to provide a new stream of data for development testing of various components and systems, as well as serving as a monitoring tool in flight applications. These applications include, but are not limited to, the regression of a combusting solid fuel surface, the ablation of the throat in a chemical rocket or the heat shield of an aeroshell, and the monitoring of erosion in long-life plasma thrusters. The rate of regression in the first application is very fast, while the second and third are increasingly slower. A recent fundamental sensor development effort has led to a novel regression, erosion, and ablation sensor technology (REAST). The REAST sensor allows for measurement of real-time surface erosion rates at a discrete surface location. The sensor is optical, using two different, co-located fiber-optics to perform the regression measurement. The disparate optical transmission properties of the two fiber-optics makes it possible to measure the regression rate by monitoring the relative light attenuation through the fibers. As the fibers regress along with the parent material in which they are embedded, the relative light intensities through the two fibers changes, providing a measure of the regression rate. The optical nature of the system makes it relatively easy to use in a variety of harsh, high temperature environments, and it is also unaffected by the presence of electric and magnetic fields. In addition, the sensor could be used to perform optical spectroscopy on the light emitted by a process and collected by fibers, giving localized measurements of various properties. The capability to perform an in-situ measurement of material regression rates is useful in addressing a variety of physical issues in various applications. An in-situ measurement allows for real-time data regarding the erosion rates, providing a quick method for

  12. High-Lift Propeller Noise Prediction for a Distributed Electric Propulsion Flight Demonstrator

    Science.gov (United States)

    Nark, Douglas M.; Buning, Pieter G.; Jones, William T.; Derlaga, Joseph M.

    2017-01-01

    Over the past several years, the use of electric propulsion technologies within aircraft design has received increased attention. The characteristics of electric propulsion systems open up new areas of the aircraft design space, such as the use of distributed electric propulsion (DEP). In this approach, electric motors are placed in many different locations to achieve increased efficiency through integration of the propulsion system with the airframe. Under a project called Scalable Convergent Electric Propulsion Technology Operations Research (SCEPTOR), NASA is designing a flight demonstrator aircraft that employs many "high-lift propellers" distributed upstream of the wing leading edge and two cruise propellers (one at each wingtip). As the high-lift propellers are operational at low flight speeds (take-off/approach flight conditions), the impact of the DEP configuration on the aircraft noise signature is also an important design consideration. This paper describes efforts toward the development of a mulit-fidelity aerodynamic and acoustic methodology for DEP high-lift propeller aeroacoustic modeling. Specifically, the PAS, OVERFLOW 2, and FUN3D codes are used to predict the aerodynamic performance of a baseline high-lift propeller blade set. Blade surface pressure results from the aerodynamic predictions are then used with PSU-WOPWOP and the F1A module of the NASA second generation Aircraft NOise Prediction Program to predict the isolated high-lift propeller noise source. Comparisons of predictions indicate that general trends related to angle of attack effects at the blade passage frequency are captured well with the various codes. Results for higher harmonics of the blade passage frequency appear consistent for the CFD based methods. Conversely, evidence of the need for a study of the effects of increased azimuthal grid resolution on the PAS based results is indicated and will be pursued in future work. Overall, the results indicate that the computational

  13. Demonstration of high current carbon nanotube enabled vertical organic field effect transistors at industrially relevant voltages

    Science.gov (United States)

    McCarthy, Mitchell

    lifetime and the potential for an all transparent display. And because carbon nanotubes (CNTs) and organics are used, CN-VFET and CN-VOLET devices are compatible with flexible displays. This dissertation describes the first ever demonstration of CN-VFETs and CN-VOLETs and relates their performance to the specific properties of the CNTs and the new device architecture. In the work that followed, the CN-VFET was systematically optimized overcoming the problems revealed in the demonstration devices. The large undesired hysteresis was decreased by 96%, the on/off ratio was improved three orders of magnitude and the operating voltages were reduced to state of the art values. Additionally, the current output per device area of the CN-VFET was demonstrated to be greater than any other low resolution patterned organic transistor by a factor of 3.9. Moreover, it was demonstrated that the CNTs induce a reorientation of the high mobility plane in small molecule organics like pentacene to coincide with the vertical direction, giving additional explanation for the large currents observed in the CN-VFET. The ability to drive high currents and potentially inexpensive fabrication may provide the solution for the AMOLED backplane problem.

  14. Analysis of Canis mitochondrial DNA demonstrates high concordance between the control region and ATPase genes

    Directory of Open Access Journals (Sweden)

    White Bradley N

    2010-07-01

    Full Text Available Abstract Background Phylogenetic studies of wild Canis species have relied heavily on the mitochondrial DNA control region (mtDNA CR to infer species relationships and evolutionary lineages. Previous analyses of the CR provided evidence for a North American evolved eastern wolf (C. lycaon, that is more closely related to red wolves (C. rufus and coyotes (C. latrans than grey wolves (C. lupus. Eastern wolf origins, however, continue to be questioned. Therefore, we analyzed mtDNA from 89 wolves and coyotes across North America and Eurasia at 347 base pairs (bp of the CR and 1067 bp that included the ATPase6 and ATPase8 genes. Phylogenies and divergence estimates were used to clarify the evolutionary history of eastern wolves, and regional comparisons of nonsynonomous to synonomous substitutions (dN/dS at the ATPase6 and ATPase8 genes were used to elucidate the potential role of selection in shaping mtDNA geographic distribution. Results We found high concordance across analyses between the mtDNA regions studied. Both had a high percentage of variable sites (CR = 14.6%; ATP = 9.7% and both phylogenies clustered eastern wolf haplotypes monophyletically within a North American evolved lineage apart from coyotes. Divergence estimates suggest the putative red wolf sequence is more closely related to coyotes (DxyCR = 0.01982 ± 0.00494 SD; DxyATP = 0.00332 ± 0.00097 SD than the eastern wolf sequences (DxyCR = 0.03047 ± 0.00664 SD; DxyATP = 0.00931 ± 0.00205 SD. Neutrality tests on both genes were indicative of the population expansion of coyotes across eastern North America, and dN/dS ratios suggest a possible role for purifying selection in the evolution of North American lineages. dN/dS ratios were higher in European evolved lineages from northern climates compared to North American evolved lineages from temperate regions, but these differences were not statistically significant. Conclusions These results demonstrate high concordance between coding

  15. High-Lift Propeller System Configuration Selection for NASA's SCEPTOR Distributed Electric Propulsion Flight Demonstrator

    Science.gov (United States)

    Patterson, Michael D.; Derlaga, Joseph M.; Borer, Nicholas K.

    2016-01-01

    Although the primary function of propellers is typically to produce thrust, aircraft equipped with distributed electric propulsion (DEP) may utilize propellers whose main purpose is to act as a form of high-lift device. These \\high-lift propellers" can be placed upstream of wing such that, when the higher-velocity ow in the propellers' slipstreams interacts with the wing, the lift is increased. This technique is a main design feature of a new NASA advanced design project called Scalable Convergent Electric Propulsion Technology Operations Research (SCEPTOR). The goal of the SCEPTOR project is design, build, and y a DEP aircraft to demonstrate that such an aircraft can be much more ecient than conventional designs. This paper provides details into the high-lift propeller system con guration selection for the SCEPTOR ight demonstrator. The methods used in the high-lift propeller system conceptual design and the tradeo s considered in selecting the number of propellers are discussed.

  16. Experimental demonstration of single-mode fiber coupling over relatively strong turbulence with adaptive optics.

    Science.gov (United States)

    Chen, Mo; Liu, Chao; Xian, Hao

    2015-10-10

    High-speed free-space optical communication systems using fiber-optic components can greatly improve the stability of the system and simplify the structure. However, propagation through atmospheric turbulence degrades the spatial coherence of the signal beam and limits the single-mode fiber (SMF) coupling efficiency. In this paper, we analyze the influence of the atmospheric turbulence on the SMF coupling efficiency over various turbulences. The results show that the SMF coupling efficiency drops from 81% without phase distortion to 10% when phase root mean square value equals 0.3λ. The simulations of SMF coupling with adaptive optics (AO) indicate that it is inevitable to compensate the high-order aberrations for SMF coupling over relatively strong turbulence. The SMF coupling efficiency experiments, using an AO system with a 137-element deformable mirror and a Hartmann-Shack wavefront sensor, obtain average coupling efficiency increasing from 1.3% in open loop to 46.1% in closed loop under a relatively strong turbulence, D/r0=15.1.

  17. CRP on Demonstrating Performance of Spent Fuel and Related Storage Systems beyond the Long Term

    International Nuclear Information System (INIS)

    Bevilacqua, Arturo

    2014-01-01

    At the initial Coordinated Research Project (CRP) planning meeting held in August 2011, international experts in spent fuel performance confirmed the value of further coordination and development of international efforts to demonstrate the performance of spent fuel and related storage system components as durations extend. Furthermore, in recognition that the Extended Storage Collaboration Program (ESCP) managed by the Electric Power Research Institute (EPRI) in the USA, from now on ESCP, provided a broad context for the research and development work to be performed in the frame of this CRP, it was agreed that its objectives should target specific ESCP needs in order to make a relevant contribution. Accordingly, the experts examined on-going gap analyses - gaps between anticipated technical needs and existing technical data - for identify the specific research objectives. Additionally, during the planning meeting it was pointed out the need to coordinate and cooperate with the OECD/NEA counterparts involved in the organization of the International Workshop planned in autumn 2013 and with the on-going third phase of the CRP on Spent Fuel Performance Assessment and Research (SPAR-III). Given the importance to assess the performance of spent fuel and related important storage system components in order to confirm the viability of very long term storage for supporting the need to extend or renew licenses for storage facilities the CRP was approved by the IAEA in November 2011. While a full range of spent fuel types and storage conditions are deployed around the world, this CRP is focused on existing systems and, more specifically, water reactor fuel in dry storage with the overall research objective to support the technical basis for water reactor spent fuel management as dry storage durations extend. In March 2012 the group of international experts who participated at the initial CRP planning meeting in August 2011 evaluated and recommended for approval 9 research

  18. A perspective on demonstrating compliance with standards for disposal of high-level radioactive wastes

    International Nuclear Information System (INIS)

    Kocher, D.C.; Smith, E.D.; O'Kelley, G.D.; Sjoreen, A.L.

    1985-01-01

    A perspective which the authors have developed on the problem of demonstrating that geologic repositories for the disposal of high-level radioactive wastes will comply with system performance standards is discussed. Their viewpoint arises from a concern that the U.S. Environmental Protection Agency's proposed environmental standard for high-level waste disposal appears to require demonstrations of compliance which are incompatible with scientific knowledge; i.e., the standard does not take into account the likely importance of unquantifiable and unresolvable uncertainty in repository performance-assessment models. A general approach to demonstrations of compliance is proposed which is thought to be compatible with the kinds of technical information that will be available for judging long-term repository performance. The authors' approach emphasizes the importance of investigating alternative conceptual models and lines of reasoning in evaluating repository performance and the importance of subjective scientific judgment in the decision-making process. (Auth.)

  19. Experimental demonstration of high fidelity entanglement distribution over decoherence channels via qubit transduction.

    Science.gov (United States)

    Lim, Hyang-Tag; Hong, Kang-Hee; Kim, Yoon-Ho

    2015-10-21

    Quantum coherence and entanglement, which are essential resources for quantum information, are often degraded and lost due to decoherence. Here, we report a proof-of-principle experimental demonstration of high fidelity entanglement distribution over decoherence channels via qubit transduction. By unitarily switching the initial qubit encoding to another, which is insensitive to particular forms of decoherence, we have demonstrated that it is possible to avoid the effect of decoherence completely. In particular, we demonstrate high-fidelity distribution of photonic polarization entanglement over quantum channels with two types of decoherence, amplitude damping and polarization-mode dispersion, via qubit transduction between polarization qubits and dual-rail qubits. These results represent a significant breakthrough in quantum communication over decoherence channels as the protocol is input-state independent, requires no ancillary photons and symmetries, and has near-unity success probability.

  20. Perspective on demonstrations of compliance for high-level waste disposal

    International Nuclear Information System (INIS)

    Kocher, D.C.; Smith, E.D.; O'Kelly, G.D.; Sjoreen, A.L.

    1984-01-01

    This paper discusses a perspective which we have developed on the problem of demonstrating compliance of high-level waste repositories with system performance standards. Our viewpoint arises from two primary concerns - first, that the US Environmental Protection Agency's proposed environmental standard for high-level waste disposal appears to require demonstrations of compliance which are incompatible with scientific knowledge, and, second, that the federal agencies involved in the licensing process may not appreciate fully the extent of unquantifiable and uresolvable uncertainty in repository performance-assessment models. We propose a general approach to demonstrations of compliance which we feel is compatible with the kinds of technical information that will be available for judging repository performance. Our approach emphasizes the importance of investigation alternative conceptual models and lines of reasoning in evaluating repository performance and the importance of subjective scientific judgment in the desision-making process. 24 references, 1 figure

  1. Demonstration of short-range wind lidar in a high-performance wind tunnel

    DEFF Research Database (Denmark)

    Pedersen, Anders Tegtmeier; Montes, Belen Fernández; Pedersen, Jens Engholm

    2012-01-01

    -speed regimes very good correlation with reference measurements was found. Furthermore different staring directions were tested and taking a simple geometrical correction into account very good correlation was again found. These measurements all demonstrate the high accuracy of the lidar and indicate a possible...

  2. A Simple Demonstration of the High-Temperature Electrical Conductivity of Glass

    Science.gov (United States)

    Chiaverina, Chris

    2014-01-01

    We usually think of glass as a good electrical insulator; this, however, is not always the case. There are several ways to show that glass becomes conducting at high temperatures, but the following approach, devised by Brown University demonstration manager Gerald Zani, may be one of the simplest to perform.

  3. Design of equipment used for high-level waste vitrification at the West Valley Demonstration Project

    International Nuclear Information System (INIS)

    Vance, R.F.; Brill, B.A.; Carl, D.E.

    1997-06-01

    The equipment as designed, started, and operated for high-level radioactive waste vitrification at the West Valley Demonstration Project in western New York State is described. Equipment for the processes of melter feed make-up, vitrification, canister handling, and off-gas treatment are included. For each item of equipment the functional requirements, process description, and hardware descriptions are presented

  4. Demonstrating Reliable High Level Waste Slurry Sampling Techniques to Support Hanford Waste Processing

    Energy Technology Data Exchange (ETDEWEB)

    Kelly, Steven E.

    2013-11-11

    The Hanford Tank Operations Contractor (TOC) and the Hanford Waste Treatment and Immobilization Plant (WTP) contractor are both engaged in demonstrating mixing, sampling, and transfer system capability using simulated Hanford High-Level Waste (HL W) formulations. This work represents one of the remaining technical issues with the high-level waste treatment mission at Hanford. The TOC must demonstrate the ability to adequately mix and sample high-level waste feed to meet the WTP Waste Acceptance Criteria and Data Quality Objectives. The sampling method employed must support both TOC and WTP requirements. To facilitate information transfer between the two facilities the mixing and sampling demonstrations are led by the One System Integrated Project Team. The One System team, Waste Feed Delivery Mixing and Sampling Program, has developed a full scale sampling loop to demonstrate sampler capability. This paper discusses the full scale sampling loops ability to meet precision and accuracy requirements, including lessons learned during testing. Results of the testing showed that the Isolok(R) sampler chosen for implementation provides precise, repeatable results. The Isolok(R) sampler accuracy as tested did not meet test success criteria. Review of test data and the test platform following testing by a sampling expert identified several issues regarding the sampler used to provide reference material used to judge the Isolok's accuracy. Recommendations were made to obtain new data to evaluate the sampler's accuracy utilizing a reference sampler that follows good sampling protocol.

  5. Demonstrating Reliable High Level Waste Slurry Sampling Techniques to Support Hanford Waste Processing

    International Nuclear Information System (INIS)

    Kelly, Steven E.

    2013-01-01

    The Hanford Tank Operations Contractor (TOC) and the Hanford Waste Treatment and Immobilization Plant (WTP) contractor are both engaged in demonstrating mixing, sampling, and transfer system capability using simulated Hanford High-Level Waste (HL W) formulations. This work represents one of the remaining technical issues with the high-level waste treatment mission at Hanford. The TOC must demonstrate the ability to adequately mix and sample high-level waste feed to meet the WTP Waste Acceptance Criteria and Data Quality Objectives. The sampling method employed must support both TOC and WTP requirements. To facilitate information transfer between the two facilities the mixing and sampling demonstrations are led by the One System Integrated Project Team. The One System team, Waste Feed Delivery Mixing and Sampling Program, has developed a full scale sampling loop to demonstrate sampler capability. This paper discusses the full scale sampling loops ability to meet precision and accuracy requirements, including lessons learned during testing. Results of the testing showed that the Isolok(R) sampler chosen for implementation provides precise, repeatable results. The Isolok(R) sampler accuracy as tested did not meet test success criteria. Review of test data and the test platform following testing by a sampling expert identified several issues regarding the sampler used to provide reference material used to judge the Isolok's accuracy. Recommendations were made to obtain new data to evaluate the sampler's accuracy utilizing a reference sampler that follows good sampling protocol

  6. Experimental demonstration of high resolution three-dimensional x-ray holography

    International Nuclear Information System (INIS)

    McNulty, I.; Trebes, J.E.; Brase, J.M.; Yorkey, T.J.; Levesque, R.; Szoke, H.; Anderson, E.H.; Jacobsen, C.

    1992-01-01

    Tomographic x-ray holography may make possible the imaging of biological objects at high resolution in three dimensions. We performed a demonstration experiment with soft x-rays to explore the feasibility of this technique. Coherent 3.2-nm undulator radiation was used to record Fourier transform holograms of a microfabricated test object from various illumination angles. The holograms were numerically reconstructed according to the principles of diffraction tomography, yielding images of the object that are well resolved in three dimensions

  7. High-Rate Field Demonstration of Large-Alphabet Quantum Key Distribution

    Science.gov (United States)

    2016-10-12

    count rate of Bob’s detectors. In this detector-limited regime , it is advantageous to increase M to encode as much information as possible in each...High- rate field demonstration of large-alphabet quantum key distribution Catherine Lee,1, 2 Darius Bunandar,1 Zheshen Zhang,1 Gregory R. Steinbrecher...October 12, 2016) 2 Quantum key distribution (QKD) enables secure symmetric key exchange for information-theoretically secure com- munication via one-time

  8. A demonstration experiment of steam-driven, high-pressure melt ejection

    International Nuclear Information System (INIS)

    Allen, M.D.; Pitch, M.; Nichols, R.T.

    1990-08-01

    A steam blowdown test was performed at the Surtsey Direct Heating Test Facility to test the steam supply system and burst diaphragm arrangement that will be used in subsequent Surtsey Direct Containment Heating (DCH) experiments. Following successful completion of the steam blowdown test, the HIPS-10S (High-Pressure Melt Streaming) experiment was conducted to demonstrate that the technology to perform steam-driven, high-pressure melt ejection (HPME) experiments has been successfully developed. In addition, the HIPS-10S experiment was used to assess techniques and instrumentation design to create the proper timing of events in HPME experiments. This document discusses the results of this test

  9. Post Irradiation Examination Plan for High-Burnup Demonstration Project Sister Rods

    Energy Technology Data Exchange (ETDEWEB)

    Scaglione, John M [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Montgomery, Rose [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Bevard, Bruce Balkcom [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2016-04-01

    This test plan describes the experimental work to be implemented by the U.S. Department of Energy (DOE) Office of Nuclear Energy (NE) to characterize high burnup (HBU) spent nuclear fuel (SNF) in conjunction with the High Burnup Dry Storage Cask Research and Development Project and serves to coordinate and integrate the multi-year experimental program to collect and develop data regarding the continued storage and eventual transport of HBU (i.e., >45 GWd/MTU) SNF. The work scope involves the development, performance, technical integration, and oversight of measurements and collection of relevant data, guided by analyses and demonstration of need.

  10. Demonstration of cathode emittance dominated high bunch charge beams in a DC gun-based photoinjector

    Energy Technology Data Exchange (ETDEWEB)

    Gulliford, Colwyn, E-mail: cg248@cornell.edu; Bartnik, Adam, E-mail: acb20@cornell.edu; Bazarov, Ivan; Dunham, Bruce; Cultrera, Luca [CLASSE, Cornell University, 161 Synchrotron Drive Ithaca, New York 14853-8001 (United States)

    2015-03-02

    We present the results of transverse emittance and longitudinal current profile measurements of high bunch charge (≥100 pC) beams produced in the DC gun-based Cornell energy recovery linac photoinjector. In particular, we show that the cathode thermal and core beam emittances dominate the final 95% and core emittances measured at 9–9.5 MeV. Additionally, we demonstrate excellent agreement between optimized 3D space charge simulations and measurement, and show that the quality of the transverse laser distribution limits the optimal simulated and measured emittances. These results, previously thought achievable only with RF guns, demonstrate that DC gun based photoinjectors are capable of delivering beams with sufficient single bunch charge and beam quality suitable for many current and next generation accelerator projects such as Energy Recovery Linacs and Free Electron Lasers.

  11. Three case reports demonstrating treatment of relatively complex orthodontic cases using a completely customised lingual appliance.

    Science.gov (United States)

    Buckley, John

    2016-01-01

    It is a commonly held misconception among Irish dentists that only minor malocclusions can be treated with lingual appliances. This article demonstrates the use of contemporary completely customised lingual orthodontic appliances to treat a diverse range of malocclusions, to a satisfactory level, and thereby may disabuse clinicians of the belief that only minor malocclusions can be treated with lingual appliances.

  12. Tolosa-Hunt syndrome. A CT demonstration of a high-density lesion

    Energy Technology Data Exchange (ETDEWEB)

    Hirata, Kazuhiro; Muramoto, Masato; Chiba, Yasuhiro; Yagishita, Saburo

    1987-08-01

    CT scan studies of the Tolosa-Hunt syndrome have seldom been reported; positive abnormal findings are especially rare. A 36-year-old man suffered from steady, boring pain behind the left eye for one year. On admission he complained of diplopia on the right lateral gaze and hypesthesea of the first and second divisions of the left trigeminal nerve. A CT scan demonstrated a slightly high-density lesion, which was homogeneously enhanced, in the left cavernous portion and the superior orbital fissure. Carotid angiograms demonstrated no abnormal finding, and the cavernous sinus venography revealed no filling of the left cavernous sinus. A left front-temporal craniotomy was performed for the purpose of biopsy. A histological examination revealed non-specific focal granulomatous pachymeningitis. He responded dramatically to systemic steroid therapy, and he became pain-free by the fourth post-operative day. This diagnosis of the Tolosa-Hunt syndrome was confirmed both clinically and etiologically; however, the CT scan after the treatment demonstrated no definitive change in the lesion. The CT scan is useful for the diagnosis of this syndrome. Considering the stage of the illness, it is possible that the high-resolution CT scan can demonstrate this lesion with an advanced technique. The clinical diagnosis is almost easy, and surgical exploration is not always necessary if there is a prompt remission upon systemic steroid therapy. However, this syndrome should be differentiated from the other causes by appropriate examinations. Some cases similar to ours, especially suspected tumors, need surgical exploration because these angiographic findings are not specific.

  13. The SOURCE Demonstration Project: Helping Disadvantaged High School Students Enroll in College

    Science.gov (United States)

    Bos, Johannes; Berman, Jacqueline

    2009-01-01

    The primary research question for this project was whether a streamlined, relatively inexpensive, counseling-based program that assists low-income high school students with the college and financial application processes can significantly increase college enrollment rates. The intervention was designed to test the hypothesis that lack of…

  14. Higs-instrument: design and demonstration of a high performance gas concentration imager

    Science.gov (United States)

    Verlaan, A. L.; Klop, W. A.; Visser, H.; van Brug, H.; Human, J.

    2017-09-01

    Climate change and environmental conditions are high on the political agenda of international governments. Laws and regulations are being setup all around the world to improve the air quality and to reduce the impact. The growth of a number of trace gasses, including CO2, Methane and NOx are especially interesting due to their environmental impact. The regulations made are being based on both models and measurements of the trend of those trace gases over the years. Now the regulations are in place also enforcement and therewith measurements become more and more important. Instruments enabling high spectral and spatial resolution as well as high accurate measurements of trace gases are required to deliver the necessary inputs. Nowadays those measurements are usually performed by space based spectrometers. The requirement for high spectral resolution and measurement accuracy significantly increases the size of the instruments. As a result the instrument and satellite becomes very expensive to develop and to launch. Specialized instruments with a small volume and the required performance will offer significant advantages in both cost and performance. Huib's Innovative Gas Sensor (HIGS, named after its inventor Huib Visser), currently being developed at TNO is an instrument that achieves exactly that. Designed to measure only a single gas concentration, opposed to deriving it from a spectrum, it achieves high performance within a small design volume. The instrument enables instantaneous imaging of the gas distribution of the selected gas. An instrument demonstrator has been developed for NO2 detection. Laboratory measurements proved the measurement technique to be successful. An on-sky measurement campaign is in preparation. This paper addresses both the instrument design as well as the demonstrated performances.

  15. In-Space Demonstration of High Performance Green Propulsion and its Impact on Small Satellites

    OpenAIRE

    Anflo, Kjell; Crowe, Ben

    2011-01-01

    This paper summarizes the pre-launch activities and the results from the in-space demonstration of a novel propulsion system on the PRISMA main satellite, using a “Green” monopropellant. This propellant is a storable ADN-based monopropellant blend (i.e. LMP-103S). The basic mission for the High Performance Green Propulsion System (HPGP) has been successfully completed and all primary objectives of TRL 7 have been met. The HPGP technology is now flight proven and ready for implementation on fu...

  16. Demonstrating multibit magnetic memory in the Fe8 high-spin molecule by muon spin rotation

    Science.gov (United States)

    Shafir, Oren; Keren, Amit; Maegawa, Satoru; Ueda, Miki; Amato, Alex; Baines, Chris

    2005-09-01

    We develop a method to detect the quantum nature of high-spin molecules using muon spin rotation and a three-step field cycle ending always with the same field. We use this method to demonstrate that the Fe8 molecule can remember six (possibly eight) different histories (bits). A wide range of fields can be used to write a particular bit, and the information is stored in discrete states. Therefore, Fe8 can be used as a model compound for multibit magnetic memory. Our experiment also paves the way for magnetic quantum tunneling detection in films.

  17. Is it possible to demonstrate compliance with the regulations for high-level-waste repositories?

    International Nuclear Information System (INIS)

    Bingham, F.W.

    1992-01-01

    The regulations that currently govern repositories for spent fuel and high-level waste require demonstrations that are sometimes described as impossible to make. To make them will require an understanding of the current and the future phenomena at repository sites; it will also require credible estimates of the probabilities that the phenomena will occur in the distant future. Experts in many fields emdash earth sciences, statistics, numerical modeling, and the law emdash have questioned whether any amount of data collection can allow modelers to meet these requirements with enough confidence to satisfy the regulators. In recent years some performance assessments have begun to shed light on this question because they use results of actual site investigations. Although these studies do not settle the question definitively, a review of a recent total-system assessment suggests that compliance may be possible to demonstrate. The review also suggests, however, that the demonstration can be only at the ''reasonable'' levels of assurance mentioned, but not defined, in the regulations

  18. Immobilization of simulated high-level radioactive waste in borosilicate glass: Pilot scale demonstrations

    International Nuclear Information System (INIS)

    Ritter, J.A.; Hutson, N.D.; Zamecnik, J.R.; Carter, J.T.

    1991-01-01

    The Integrated DWPF Melter System (IDMS), operated by the Savannah River Laboratory, is a pilot scale facility used in support of the start-up and operation of the Department of Energy's Defense Waste Processing Facility. The IDMS has successfully demonstrated, on an engineering scale (one-fifth), that simulated high level radioactive waste (HLW) sludge can be chemically treated with formic acid to adjust both its chemical and physical properties, and then blended with simulated precipitate hydrolysis aqueous (PHA) product and borosilicate glass frit to produce a melter feed which can be processed into a durable glass product. The simulated sludge, PHA and frit were blended, based on a product composition program, to optimize the loading of the waste glass as well as to minimize those components which can cause melter processing and/or glass durability problems. During all the IDMS demonstrations completed thus far, the melter feed and the resulting glass that has been produced met all the required specifications, which is very encouraging to future DWPF operations. The IDMS operations also demonstrated that the volatile components of the melter feed (e.g., mercury, nitrogen and carbon, and, to a lesser extent, chlorine, fluorine and sulfur) did not adversely affect the melter performance or the glass product

  19. The HAW project: demonstration facility for the disposal of high-level waste in salt

    International Nuclear Information System (INIS)

    Rothfuchs, T.

    1991-01-01

    This report is the so-called Synthesis report 1985-1989 of the international HAW project performed in the 800 m level of the ASSE salt mine in the Federal Republic of Germany. The major objective of this project is the pilot testing and demonstration of safe methods for the final disposal of high-level radioactive waste in geological salt-deposits. The HAW-project is carried out by the GSF-Institut fuer Tieflagerung (IFT) in cooperation with the French Agence Nationale pour la Gestion des Dechets Radioactifs (ANDRA); the Spanish Empresa Nacional de Residuos Radioactivos S.A (ENRESA) and the Netherlands Energy Research Foundation (ECN). During the years 1985 to 1989 the underground test field was excavated and after some delays in the licensing procedure, the emplacement of 30 vitrified highly radioactive canisters (containers) is now envisaged for early 1991. 32 refs; 76 figs., 11 tabs

  20. Experimental demonstration of producing high resolution zone plates by spatial-frequency multiplication

    International Nuclear Information System (INIS)

    Yun, W.B.; Howells, M.R.

    1987-01-01

    In an earlier publication, the possibility of producing high resolution zone plates for x-ray applications by spatial-frequency multiplication was analyzed theoretically. The theory predicted that for a daughter zone plate generated from the interference of mth and nth diffraction orders of a parent zone plate, its primary focal spot size and focal length are one (m + n)th of their counterparts of the parent zone plate, respectively. It was also shown that a zone plate with the outermost zone width of as small as 13.8 nm might be produced by this technique. In this paper, we report an experiment which we carried out with laser light (λ = 4166A) for demonstrating this technique. In addition, an outlook for producing high resolution zone plates for x-ray application is briefly discussed

  1. The HAW project: demonstration facility for the disposal of high-level waste in salt

    International Nuclear Information System (INIS)

    Rothfuchs, T.

    1991-01-01

    This publication is the interim report 1988-89 of the international HAW project performed in the 800 m level of the Asse salt mine in the Federal Republic of Germany. The major objective of this project is the pilot testing and demonstration of safe methods for the final disposal of high-level radioactive waste in geological salt deposits. The HAW-project is carried out by the GSF-Institut fuer Tieflagerung (IFT) in cooperation with the French Agence Nationale pour la Gestion des Dechets Radioactifs (ANDRA); the Spanish Empresa Nacional de Residuos Radiactivos S.A. (ENRESA) and the Netherlands Energy Research Foundation (ECN). After some delays in the licensing procedure the emplacement of 30 vitrified highly radioactive canisters (containers) is now envisaged for early 1991. 20 refs.; 92 figs.; 14 tabs

  2. Demonstration of a transient high gain nickel-like xenon ion x-ray laser

    International Nuclear Information System (INIS)

    Lu, Peixiang; Kawachi, Tetsuya; Kishimoto, Maki

    2003-01-01

    We demonstrate a high gain nickel-like xenon ion x-ray laser using a picosecond-laser-irradiated gas puff target. The elongated x-ray laser plasma column was produced by irradiating the gas puff target with line-focused double picosecond laser pulses with a total energy of 18 J in a travelling-wave excitation scheme. Strong lasing at 9.98 nm was observed, and a high gain coefficient of 17.4 cm -1 was measured on the transient collisionally excited 4d-4p, J=0-1 transition for nickel-like xenon ion with target lengths up to 0.45 cm. A weak nickel-like lasing line at a shorter wavelength of 9.64 nm was also observed with a gain coefficient of 5.9 cm -1 . (author)

  3. Curved sensors for compact high-resolution wide-field designs: prototype demonstration and optical characterization

    Science.gov (United States)

    Chambion, Bertrand; Gaschet, Christophe; Behaghel, Thibault; Vandeneynde, Aurélie; Caplet, Stéphane; Gétin, Stéphane; Henry, David; Hugot, Emmanuel; Jahn, Wilfried; Lombardo, Simona; Ferrari, Marc

    2018-02-01

    Over the recent years, a huge interest has grown for curved electronics, particularly for opto-electronics systems. Curved sensors help the correction of off-axis aberrations, such as Petzval Field Curvature, astigmatism, and bring significant optical and size benefits for imaging systems. In this paper, we first describe advantages of curved sensor and associated packaging process applied on a 1/1.8'' format 1.3Mpx global shutter CMOS sensor (Teledyne EV76C560) into its standard ceramic package with a spherical radius of curvature Rc=65mm and 55mm. The mechanical limits of the die are discussed (Finite Element Modelling and experimental), and electro-optical performances are investigated. Then, based on the monocentric optical architecture, we proposed a new design, compact and with a high resolution, developed specifically for a curved image sensor including optical optimization, tolerances, assembly and optical tests. Finally, a functional prototype is presented through a benchmark approach and compared to an existing standard optical system with same performances and a x2.5 reduction of length. The finality of this work was a functional prototype demonstration on the CEA-LETI during Photonics West 2018 conference. All these experiments and optical results demonstrate the feasibility and high performances of systems with curved sensors.

  4. Decontamination and radioactivity measurement on building surfaces related to dismantling of Japan power demonstration reactor (JPDR)

    International Nuclear Information System (INIS)

    Hatakeyama, Mutsuo; Tachibana, Mitsuo; Yanagihara, Satoshi

    1997-12-01

    In the final stage of dismantling activities for decommissioning a nuclear power plant, building structures have to be demolished to release the site for unrestricted use. Since building structures are generally made from massive reinforced concrete materials, it is not a rational way to treat all concrete materials arising from its demolition as radioactive waste. Segregation of radioactive parts from building structures is therefore indispensable. The rational procedures were studied for demolition of building structures by treating arising waste as non-radioactive materials, based on the concept established by Nuclear Safety Commission, then these were implemented in the following way by the JPDR dismantling demonstration project. Areas of the JPDR facilities are categorized into two groups : possibly contaminated areas, and possibly non-contaminated areas, based on the document of the reactor operation. Radioactivity on the building surfaces was then measured to confirm that the qualitative categorization is reasonable. After that, building surfaces were decontaminated in such a way that the contaminated layers were removed with enough margin to separate radioactive parts from non-radioactive building structures. Thought it might be possible to demolish the building structures by treating arising waste as non-radioactive materials, confirmation survey for radioactivity was conducted to show that there is no artificial radioactive nuclides produced by operation in the facility. This report describes the procedures studied on measurement of radioactivity and decontamination, and the results of its implementation in the JPDR dismantling demonstration project. (author)

  5. Single acquisition electrical property mapping based on relative coil sensitivities: A proof-of-concept demonstration

    NARCIS (Netherlands)

    Marques, J.P.; Sodickson, D.K.; Ipek, O.; Collins, C.M.; Gruetter, R.

    2015-01-01

    PurposeAll methods presented to date to map both conductivity and permittivity rely on multiple acquisitions to compute quantitatively the magnitude of radiofrequency transmit fields, B-1(+). In this work, we propose a method to compute both conductivity and permittivity based solely on relative

  6. The HAW-project: Demonstration facility for the disposal of high-level waste in salt

    International Nuclear Information System (INIS)

    Rothfuchs, T.; Duijves, K.A.

    1990-04-01

    The HAW-project plants the testwise emplacement of 30 vitrified highly radioactive canisters containing Cs-137 and Sr-90 at the 800 m level of the Asse salt mine for a testing period of approximately five years. The major objective of this project is the pilot testing and demonstration of safe methods for the final disposal of high-level radioactive waste (HAW) in geological salt formations. During the years 1985 to 1989 the underground test field was excavated, the measuring equipment installed, and two preceedings inactive electrical tests taken into operation. Furthermore, the components of a system for transportation and emplacement of highly radioactive canisters was fabricated, installed, and preliminarily tested. After some delays in the licensing procedure the emplacement of the 30 radioactive canisters is now envisaged for early 1991. For handling of the radioactive canisters and their emplacement into the boreholes a system consisting of a transport cask, a transport vehicle, a disposal machine, and of a borehole slider has been developed and will be tested. The actual scientific investigation programme is based on the estimation and observation of the interaction between the radioactive canisters and the rock salt. This programme includes measurement of thermally and radiolytically induced water and gas release from the rock salt and the radiolytical decomposition of salt minerals. Also the thermally induced stress and deformation fields in the surrounding rock mass will be investigated carefully. (orig./HP)

  7. A High-Resolution Terrestrial Modeling System (TMS): A Demonstration in China

    Science.gov (United States)

    Duan, Q.; Dai, Y.; Zheng, X.; Ye, A.; Ji, D.; Chen, Z.

    2013-12-01

    This presentation describes a terrestrial modeling system (TMS) developed at Beijing Normal University. The TMS is designed to be driven by multi-sensor meteorological and land surface observations, including those from satellites and land based observing stations. The purposes of the TMS are (1) to provide a land surface parameterization scheme fully capable of being coupled with the Earth system models; (2) to provide a standalone platform for retrospective historical simulation and for forecasting of future land surface processes at different space and time scales; and (3) to provide a platform for studying human-Earth system interactions and for understanding climate change impacts. This system is built on capabilities among several groups at BNU, including the Common Land Model (CoLM) system, high-resolution atmospheric forcing data sets, high resolution land surface characteristics data sets, data assimilation and uncertainty analysis platforms, ensemble prediction platform, and high-performance computing facilities. This presentation intends to describe the system design and demonstrate the capabilities of TMS with results from a China-wide application.

  8. The innovation of cryo-SEM freeze-fracturing methodology demonstrated on high pressure frozen biofilm.

    Science.gov (United States)

    Hrubanova, Kamila; Nebesarova, Jana; Ruzicka, Filip; Krzyzanek, Vladislav

    2018-04-22

    In this study we present an innovative method for the preparation of fully hydrated samples of microbial biofilms of cultures Staphylococcus epidermidis, Candida parapsilosis and Candida albicans. Cryo-scanning electron microscopy (cryo-SEM) and high-pressure freezing (HPF) rank among cutting edge techniques in the electron microscopy of hydrated samples such as biofilms. However, the combination of these techniques is not always easily applicable. Therefore, we present a method of combining high-pressure freezing using EM PACT2 (Leica Microsystems), which fixes hydrated samples on small sapphire discs, with a high resolution SEM equipped with the widely used cryo-preparation system ALTO 2500 (Gatan). Using a holder developed in house, a freeze-fracturing technique was applied to image and investigate microbial cultures cultivated on the sapphire discs. In our experiments, we focused on the ultrastructure of the extracellular matrix produced during cultivation and the relationships among microbial cells in the biofilm. The main goal of our investigations was the detailed visualization of areas of the biofilm where the microbial cells adhere to the substrate/surface. We show the feasibility of this technique, which is clearly demonstrated in experiments with various freeze-etching times. Copyright © 2018 Elsevier Ltd. All rights reserved.

  9. Preliminary Demonstration Reactor Point Design for the Fluoride Salt-Cooled High-Temperature Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Qualls, A. L. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Betzler, Benjamin R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Brown, Nicholas R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Carbajo, Juan [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Greenwood, Michael Scott [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Hale, Richard Edward [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Harrison, Thomas J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Powers, Jeffrey J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Robb, Kevin R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Terrell, Jerry W. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2015-12-01

    Development of the Fluoride Salt-Cooled High-Temperature Reactor (FHR) Demonstration Reactor (DR) is a necessary intermediate step to enable commercial FHR deployment through disruptive and rapid technology development and demonstration. The FHR DR will utilize known, mature technology to close remaining gaps to commercial viability. Lower risk technologies are included in the initial FHR DR design to ensure that the reactor can be built, licensed, and operated within an acceptable budget and schedule. These technologies include tristructural-isotropic (TRISO) particle fuel, replaceable core structural material, the use of that same material for the primary and intermediate loops, and tube-and-shell heat exchangers. This report provides an update on the development of the FHR DR. At this writing, the core neutronics and thermal hydraulics have been developed and analyzed. The mechanical design details are still under development and are described to their current level of fidelity. It is anticipated that the FHR DR can be operational within 10 years because of the use of low-risk, near-term technology options.

  10. Preliminary Demonstration Reactor Point Design for the Fluoride Salt-Cooled High-Temperature Reactor

    International Nuclear Information System (INIS)

    Qualls, A. L.; Betzler, Benjamin R.; Brown, Nicholas R.; Carbajo, Juan; Greenwood, Michael Scott; Hale, Richard Edward; Harrison, Thomas J.; Powers, Jeffrey J.; Robb, Kevin R.; Terrell, Jerry W.

    2015-01-01

    Development of the Fluoride Salt-Cooled High-Temperature Reactor (FHR) Demonstration Reactor (DR) is a necessary intermediate step to enable commercial FHR deployment through disruptive and rapid technology development and demonstration. The FHR DR will utilize known, mature technology to close remaining gaps to commercial viability. Lower risk technologies are included in the initial FHR DR design to ensure that the reactor can be built, licensed, and operated within an acceptable budget and schedule. These technologies include tristructural-isotropic (TRISO) particle fuel, replaceable core structural material, the use of that same material for the primary and intermediate loops, and tube-and-shell heat exchangers. This report provides an update on the development of the FHR DR. At this writing, the core neutronics and thermal hydraulics have been developed and analyzed. The mechanical design details are still under development and are described to their current level of fidelity. It is anticipated that the FHR DR can be operational within 10 years because of the use of low-risk, near-term technology options.

  11. Delusions of expertise: the high standard of proof needed to demonstrate skills at horserace handicapping.

    Science.gov (United States)

    Browne, Matthew; Rockloff, Matthew J; Blaszcynski, Alex; Allcock, Clive; Windross, Allen

    2015-03-01

    Gamblers who participate in skill-oriented games (such as poker and sports-betting) are motivated to win over the long-term, and some monitor their betting outcomes to evaluate their performance and proficiency. In this study of Australian off-track horserace betting, we investigated which levels of sustained returns would be required to establish evidence of skill/expertise. We modelled a random strategy to simulate 'naïve' play, in which equal bets were placed on randomly selected horses using a representative sample of 211 weekend races. Results from a Monte Carlo simulation yielded a distribution of return-on-investments for varying number of bets (N), showing surprising volatility, even after a large number of repeated bets. After adjusting for the house advantage, a gambler would have to place over 10,000 bets in individual races with net returns exceeding 9 % to be reasonably considered an expert punter (α = .05). Moreover, a record of fewer bets would require even greater returns for demonstrating expertise. As such, validated expertise is likely to be rare among race bettors. We argue that the counter-intuitively high threshold for demonstrating expertise by tracking historical performance is likely to exacerbate known cognitive biases in self-evaluation of expertise.

  12. International Interlaboratory Digital PCR Study Demonstrating High Reproducibility for the Measurement of a Rare Sequence Variant.

    Science.gov (United States)

    Whale, Alexandra S; Devonshire, Alison S; Karlin-Neumann, George; Regan, Jack; Javier, Leanne; Cowen, Simon; Fernandez-Gonzalez, Ana; Jones, Gerwyn M; Redshaw, Nicholas; Beck, Julia; Berger, Andreas W; Combaret, Valérie; Dahl Kjersgaard, Nina; Davis, Lisa; Fina, Frederic; Forshew, Tim; Fredslund Andersen, Rikke; Galbiati, Silvia; González Hernández, Álvaro; Haynes, Charles A; Janku, Filip; Lacave, Roger; Lee, Justin; Mistry, Vilas; Pender, Alexandra; Pradines, Anne; Proudhon, Charlotte; Saal, Lao H; Stieglitz, Elliot; Ulrich, Bryan; Foy, Carole A; Parkes, Helen; Tzonev, Svilen; Huggett, Jim F

    2017-02-07

    This study tested the claim that digital PCR (dPCR) can offer highly reproducible quantitative measurements in disparate laboratories. Twenty-one laboratories measured four blinded samples containing different quantities of a KRAS fragment encoding G12D, an important genetic marker for guiding therapy of certain cancers. This marker is challenging to quantify reproducibly using quantitative PCR (qPCR) or next generation sequencing (NGS) due to the presence of competing wild type sequences and the need for calibration. Using dPCR, 18 laboratories were able to quantify the G12D marker within 12% of each other in all samples. Three laboratories appeared to measure consistently outlying results; however, proper application of a follow-up analysis recommendation rectified their data. Our findings show that dPCR has demonstrable reproducibility across a large number of laboratories without calibration. This could enable the reproducible application of molecular stratification to guide therapy and, potentially, for molecular diagnostics.

  13. High Density Hydrogen Storage System Demonstration Using NaAlH4 Based Complex Compound Hydrides

    Energy Technology Data Exchange (ETDEWEB)

    Daniel A. Mosher; Xia Tang; Ronald J. Brown; Sarah Arsenault; Salvatore Saitta; Bruce L. Laube; Robert H. Dold; Donald L. Anton

    2007-07-27

    This final report describes the motivations, activities and results of the hydrogen storage independent project "High Density Hydrogen Storage System Demonstration Using NaAlH4 Based Complex Compound Hydrides" performed by the United Technologies Research Center under the Department of Energy Hydrogen Program, contract # DE-FC36-02AL67610. The objectives of the project were to identify and address the key systems technologies associated with applying complex hydride materials, particularly ones which differ from those for conventional metal hydride based storage. This involved the design, fabrication and testing of two prototype systems based on the hydrogen storage material NaAlH4. Safety testing, catalysis studies, heat exchanger optimization, reaction kinetics modeling, thermochemical finite element analysis, powder densification development and material neutralization were elements included in the effort.

  14. Operating experience during high-level waste vitrification at the West Valley Demonstration Project

    International Nuclear Information System (INIS)

    Valenti, P.J.; Elliott, D.I.

    1999-01-01

    This report provides a summary of operational experiences, component and system performance, and lessons learned associated with the operation of the Vitrification Facility (VF) at the West Valley Demonstration Project (WVDP). The VF was designed to convert stored high-level radioactive waste (HLW) into a stable waste form (borosilicate glass) suitable for disposal in a federal repository. Following successful completion on nonradioactive test, HLW processing began in July 1995. Completion of Phase 1 of HLW processing was reached on 10 June 1998 and represented the processing of 9.32 million curies of cesium-137 (Cs-137) and strontium-90 (Sr-90) to fill 211 canisters with over 436,000 kilograms of glass. With approximately 85% of the total estimated curie content removed from underground waste storage tanks during Phase 1, subsequent operations will focus on removal of tank heel wastes

  15. Tuberculosis related drug-lipid interactions demonstrated by evanescent field biosensor

    CSIR Research Space (South Africa)

    Lemmer, Yolandy

    2009-08-01

    Full Text Available stream_source_info Lemmer1_2009.pdf.txt stream_content_type text/plain stream_size 6475 Content-Encoding ISO-8859-1 stream_name Lemmer1_2009.pdf.txt Content-Type text/plain; charset=ISO-8859-1 Tuberculosis related drug... of Pretoria, Pretoria, South Africa bPolymers and Bioceramics, MSM, CSIR, Pretoria, South Africa Mycolic acids (MA), depicted in Fig.1, which are part of the cell envelope of Mycobacterium tuberculosis, play a major role in the pathogenesis of the bacteria...

  16. Demonstration of relatively new electron dosimetry measurement techniques on the Mevatron 80

    International Nuclear Information System (INIS)

    Meyer, J.A.; Palta, J.R.; Hogstrom, K.R.

    1984-01-01

    A comprehensive set of electron dosimetry measurements at 7, 10, 12, 15, and 18 MeV was made on a Mevatron 80. Dosimetry measurements presented include percentage depth dose, dose in the buildup region, field size dependence of output, output at extended distances, lead transmission measurements, and isodose curves. These beam measurements are presented to document the electron beam characteristics of this linear accelerator. Three relatively new dosimetry techniques, which have not been standardly used in the past, are illustrated. One technique determines the depth dose of fields too small to measure. A second technique accurately converts depth dose measured in polystyrene to depth dose in water. A third technique calculates the output at extended distances

  17. West Valley demonstration project: alternative processes for solidifying the high-level wastes

    International Nuclear Information System (INIS)

    Holton, L.K.; Larson, D.E.; Partain, W.L.; Treat, R.L.

    1981-10-01

    In 1980, the US Department of Energy (DOE) established the West Valley Solidification Project as the result of legislation passed by the US Congress. The purpose of this project was to carry out a high level nuclear waste management demonstration project at the Western New York Nuclear Service Center in West Valley, New York. The DOE authorized the Pacific Northwest Laboratory (PNL), which is operated by Battelle Memorial Institute, to assess alternative processes for treatment and solidification of the WNYNSC high-level wastes. The Process Alternatives Study is the suject of this report. Two pretreatment approaches and several waste form processes were selected for evaluation in this study. The two waste treatment approaches were the salt/sludge separation process and the combined waste process. Both terminal and interim waste form processes were studied. The terminal waste form processes considered were: borosilicate glass, low-alkali glass, marbles-in-lead matrix, and crystallinolecular potential and molecular dynamics calculations of the effect are yet to be completed. Cous oxide was also investigated. The reaction is first order in nitrite ion, second order in hydrogen ion, and between zero and first order in hydroxylamine monosulfonate, depending on the concentration

  18. Fluoride Salt-Cooled High-Temperature Demonstration Reactor Point Design

    Energy Technology Data Exchange (ETDEWEB)

    Qualls, A. L. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Brown, Nicholas R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Betzler, Benjamin R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Carbajo, Juan [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Hale, Richard Edward [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Harrison, Thomas J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Powers, Jeffrey J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Robb, Kevin R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Terrell, Jerry W. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Wysocki, Aaron J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2016-02-01

    The fluoride salt-cooled high-temperature reactor (FHR) demonstration reactor (DR) is a concept for a salt-cooled reactor with 100 megawatts of thermal output (MWt). It would use tristructural-isotropic (TRISO) particle fuel within prismatic graphite blocks. FLiBe (2 LiF-BeF2) is the reference primary coolant. The FHR DR is designed to be small, simple, and affordable. Development of the FHR DR is a necessary intermediate step to enable near-term commercial FHRs. Lower risk technologies are purposely included in the initial FHR DR design to ensure that the reactor can be built, licensed, and operated within an acceptable budget and schedule. These technologies include TRISO particle fuel, replaceable core structural material, the use of that same material for the primary and intermediate loops, and tube-and-shell primary-to-intermediate heat exchangers. Several preconceptual and conceptual design efforts that have been conducted on FHR concepts bear a significant influence on the FHR DR design. Specific designs include the Oak Ridge National Laboratory (ORNL) advanced high-temperature reactor (AHTR) with 3400/1500 MWt/megawatts of electric output (MWe), as well as a 125 MWt small modular AHTR (SmAHTR) from ORNL. Other important examples are the Mk1 pebble bed FHR (PB-FHR) concept from the University of California, Berkeley (UCB), and an FHR test reactor design developed at the Massachusetts Institute of Technology (MIT). The MIT FHR test reactor is based on a prismatic fuel platform and is directly relevant to the present FHR DR design effort. These FHR concepts are based on reasonable assumptions for credible commercial prototypes. The FHR DR concept also directly benefits from the operating experience of the Molten Salt Reactor Experiment (MSRE), as well as the detailed design efforts for a large molten salt reactor concept and its breeder variant, the Molten Salt Breeder Reactor. The FHR DR technology is most representative of the 3400 MWt AHTR

  19. Demonstration-Scale High-Cell-Density Fermentation of Pichia pastoris.

    Science.gov (United States)

    Liu, Wan-Cang; Zhu, Ping

    2018-01-01

    Pichia pastoris has been one of the most successful heterologous overexpression systems in generating proteins for large-scale production through high-cell-density fermentation. However, optimizing conditions of the large-scale high-cell-density fermentation for biochemistry and industrialization is usually a laborious and time-consuming process. Furthermore, it is often difficult to produce authentic proteins in large quantities, which is a major obstacle for functional and structural features analysis and industrial application. For these reasons, we have developed a protocol for efficient demonstration-scale high-cell-density fermentation of P. pastoris, which employs a new methanol-feeding strategy-biomass-stat strategy and a strategy of increased air pressure instead of pure oxygen supplement. The protocol included three typical stages of glycerol batch fermentation (initial culture phase), glycerol fed-batch fermentation (biomass accumulation phase), and methanol fed-batch fermentation (induction phase), which allows direct online-monitoring of fermentation conditions, including broth pH, temperature, DO, anti-foam generation, and feeding of glycerol and methanol. Using this protocol, production of the recombinant β-xylosidase of Lentinula edodes origin in 1000-L scale fermentation can be up to ~900 mg/L or 9.4 mg/g cells (dry cell weight, intracellular expression), with the specific production rate and average specific production of 0.1 mg/g/h and 0.081 mg/g/h, respectively. The methodology described in this protocol can be easily transferred to other systems, and eligible to scale up for a large number of proteins used in either the scientific studies or commercial purposes.

  20. Experimental and analytical study for demonstration program on shielding of casks for high-level wastes

    International Nuclear Information System (INIS)

    Ueki, K.; Nakazawa, M.; Hattorl, S.; Ozaki, S.; Tamaki, H.; Kadotani, H.; Ishizuka, T.; Ishikawa, S.

    1993-01-01

    The following remarks were obtained from the experiment and the DOT 3.5 and the MCNP analyses on the gamma ray and the neutron dose equivalent rates in the cask of interest. 1. The cask has thinner neutron shielding parts around the trunnions. Significant neutrons streaming around the trunnion parts was observed which was also cleared by the MCNP analysis for the 252 Cf source experiment. Accordingly, detailed neutron streaming calculations are required to evaluate the dose levels around the trunnions when loading the vitrified high-level wastes. 2. The room-scattered obstructive neutrons, mainly originating from the neutrons penetrating around the trunnions, at the top and the bottom of the cask are reduced significantly by preparing the water tank at the top and the water layer at the bottom. Therefore, a more accurate experiment is to be carried out in the future shielding experiment especially for neutrons. However, because the water tank and the layer do not exist in the actual high-level wastes transport cask, the experiment without the water tank and layer are not dispensable to demonstrate the transport conditions of the actual cask, too. 3. The gamma-ray and the neutron dose equivalent rate distributions obtained from the DOT 3.5 and the MCNP calculations, respectively, agreed closely with the measured values in the cask areas of interest. Accordingly, the DOT 3.5 code and the MCNP code with the NESX estimator can be employed not only for the shielding analysis of the future experiments, but also for making a safety analysis report of high-level wastes transport casks. (J.P.N.)

  1. Demonstration of a performance assessment methodology for high-level radioactive waste disposal in basalt formations

    International Nuclear Information System (INIS)

    Bonano, E.J.; Davis, P.A.; Shipers, L.R.; Brinster, K.F.; Beyler, W.E.; Updegraff, C.D.; Shepherd, E.R.; Tilton, L.M.; Wahi, K.K.

    1989-06-01

    This document describes a performance assessment methodology developed for a high-level radioactive waste repository mined in deep basalt formations. This methodology is an extension of an earlier one applicable to bedded salt. The differences between the two methodologies arise primarily in the modeling of round-water flow and radionuclide transport. Bedded salt was assumed to be a porous medium, whereas basalt formations contain fractured zones. Therefore, mathematical models and associated computer codes were developed to simulate the aforementioned phenomena in fractured media. The use of the methodology is demonstrated at a hypothetical basalt site by analyzing seven scenarios: (1) thermohydrological effects caused by heat released from the repository, (2) mechanohydrological effects caused by an advancing and receding glacier, (3) normal ground-water flow, (4) pumping of ground water from a confined aquifer, (5) rerouting of a river near the repository, (6) drilling of a borehole through the repository, and (7) formation of a new fault intersecting the repository. The normal ground-water flow was considered the base-case scenario. This scenario was used to perform uncertainty and sensitivity analyses and to demonstrate the existing capabilities for assessing compliance with the ground-water travel time criterion and the containment requirements. Most of the other scenarios were considered perturbations of the base case, and a few were studied in terms of changes with respect to initial conditions. The potential impact of these scenarios on the long-term performance of the disposal system was ascertained through comparison with the base-case scenario or the undisturbed initial conditions. 66 refs., 106 figs., 27 tabs

  2. ARC: A compact, high-field, disassemblable fusion nuclear science facility and demonstration power plant

    Science.gov (United States)

    Sorbom, Brandon; Ball, Justin; Palmer, Timothy; Mangiarotti, Franco; Sierchio, Jennifer; Bonoli, Paul; Kasten, Cale; Sutherland, Derek; Barnard, Harold; Haakonsen, Christian; Goh, Jon; Sung, Choongki; Whyte, Dennis

    2014-10-01

    The Affordable, Robust, Compact (ARC) reactor conceptual design aims to reduce the size, cost, and complexity of a combined Fusion Nuclear Science Facility (FNSF) and demonstration fusion pilot power plant. ARC is a 270 MWe tokamak reactor with a major radius of 3.3 m, a minor radius of 1.1 m, and an on-axis magnetic field of 9.2 T. ARC has Rare Earth Barium Copper Oxide (REBCO) superconducting toroidal field coils with joints to allow disassembly, allowing for removal and replacement of the vacuum vessel as a single component. Inboard-launched current drive of 25 MW LHRF power and 13.6 MW ICRF power is used to provide a robust, steady state core plasma far from disruptive limits. ARC uses an all-liquid blanket, consisting of low pressure, slowly flowing Fluorine Lithium Beryllium (FLiBe) molten salt. The liquid blanket acts as a working fluid, coolant, and tritium breeder, and minimizes the solid material that can become activated. The large temperature range over which FLiBe is liquid permits blanket operation at 800-900 K with single phase fluid cooling and allows use of a high-efficiency Brayton cycle for electricity production in the secondary coolant loop.

  3. A demonstration test of 4-group partitioning process with real high-level liquid waste

    Energy Technology Data Exchange (ETDEWEB)

    Morita, Y.; Yamaguchi, I.; Fujiwara, T.; Koizumi, H.; Tachimori, S. [Japan Atomic Energy Research Institute, Tokai-Mura, Ibaraki-Ken (Japan)

    2000-07-01

    The demonstration test of 4-Group Partitioning Process with concentrated real high-level liquid waste (HLLW) was carried out in the Partitioning Test Facility installed in a hot cell. More than 99.998% of Am and Cm were extracted from the HLLW with the organic solvent containing 0.5 M DIDPA - 0.1 M TBP, and more than 99.98% of Am and Cm were back-extracted with 4 M nitric acid. Np and Pu were extracted simultaneously, and more than 99.93% of Np and more than 99.98% of Pu were back-extracted with oxalic acid. In the denitration step for the separation of Tc and platinum group metals, more than 90% of Rh and more than 97% of Pd were precipitated. About half of Ru were remained in the de-nitrated solution, but the remaining Ru were quantitatively precipitated by neutralization of the de-nitrated solution to pH 6.7. In the adsorption step, both Sr and Cs were separated effectively. Decontamination factors for Cs and Sr were more than 10{sup 6} and 10{sup 4} respectively in all effluent samples. (authors)

  4. DEMONSTRATION AND EVALUATION OF POTENTIAL HIGH LEVEL WASTE MELTER DECONTAMINATION TECHNOLOGIES FOR SAVANNAH RIVER SITE

    International Nuclear Information System (INIS)

    Weger, Hans; Kodanda, Raja Tilek Meruva; Mazumdar, Anindra; Srivastava, Rajiv Ph.D.; Ebadian, M.A. Ph.D.

    2003-01-01

    Four hand-held tools were tested for failed high-level waste melter decontamination and decommissioning (D and D). The forces felt by the tools during operation were measured using a tri-axial accelerometer since they will be operated by a remote manipulator. The efficiency of the tools was also recorded. Melter D and D consists of three parts: (1) glass fracturing: removing from the furnace the melted glass that can not be poured out through normal means, (2) glass cleaning: removing the thin layer of glass that has formed over the surface of the refractory material, and (3) K-3 refractory breakup: removing the K-3 refractory material. Surrogate glass, from a formula provided by the Savannah River Site, was melted in a furnace and poured into steel containers. K-3 refractory material, the same material used in the Defense Waste Processing Facility, was utilized for the demonstrations. Four K-3 blocks were heated at 1150 C for two weeks with a glass layer on top to simulate the hardened glass layer on the refractory surface in the melter. Tools chosen for the demonstrations were commonly used D and D tools, which have not been tested specifically for the different aspects of melter D and D. A jackhammer and a needle gun were tested for glass fracturing; a needle gun and a rotary grinder with a diamond face wheel (diamond grinder) were tested for glass cleaning; and a jackhammer, diamond grinder, and a circular saw with a diamond blade were tested for refractory breakup. The needle gun was not capable of removing or fracturing the surrogate glass. The diamond grinder only had a removal rate of 3.0 x 10-4 kg/s for K-3 refractory breakup and needed to be held firmly against the material. However, the diamond grinder was effective for glass cleaning, with a removal rate of 3.9 cm2/s. The jackhammer was successful in fracturing glass and breaking up the K-3 refractory block. The jackhammer had a glass-fracturing rate of 0.40 kg/s. The jackhammer split the K-3 refractory

  5. The Fort McMurray Demonstration Project in social marketing: health- and safety-related behaviour among oil sands workers.

    Science.gov (United States)

    Guidotti, T L; Watson, L; Wheeler, M; Jhangri, G S

    1996-08-01

    This is the first round in a series of surveys conducted in Fort McMurray as part of the Fort McMurray Demonstration Project in social marketing. This component of the survey was intended to focus on the most prominent group of employed workers in the community and to compare their patterns of response with the community as a whole. Respondents to the survey were overwhelmingly male (96%), married (72.9%) and living in households of two to five persons (87.9%). They were predominantly aged 30-44 (55%) and graduates of high school (53.5%). Younger male workers (below age 30) were more likely to have a high school diploma (78.3%) or some additional technical or vocational training (21.7% compared to 12.5% overall) and to be unmarried or separated. Attitudes toward safety-related behaviours were stronger than for respondents from the community as a whole. Approximately 70-100% of all age groups and both sexes showed strong agreement with attitudes involving child car seats and the unacceptability of drinking and driving. These attitudes include strong advocacy of vigorous enforcement of occupational health and safety standards. However, they showed a variability similar to the community as a whole in behaviour at home compared to work, generally reporting more consistent use of personal protection on the job than in their own homes, particularly hearing protection. Even so, they were much less likely to perform stretching and warm-up exercises prior to exertion than community residents in general. The potential may exist to transfer the technology and attitudes from workplace health and safety to community safety. One possible strategy to accomplish this is to involve workers in this industry directly in community initiatives. This strategy may be generalizable to any community in which there are major employers who place a heavy emphasis on risk control and occupational health and safety.

  6. High Temperature Syngas Cleanup Technology Scale-up and Demonstration Project

    Energy Technology Data Exchange (ETDEWEB)

    Gardner, Ben [Research Triangle Inst. (RTI), Research Triangle Park, NC (United States); Turk, Brian [Research Triangle Inst. (RTI), Research Triangle Park, NC (United States); Denton, David [Research Triangle Inst. (RTI), Research Triangle Park, NC (United States); Gupta, Raghubir [Research Triangle Inst. (RTI), Research Triangle Park, NC (United States)

    2015-09-30

    Gasification is a technology for clean energy conversion of diverse feedstocks into a wide variety of useful products such as chemicals, fertilizers, fuels, electric power, and hydrogen. Existing technologies can be employed to clean the syngas from gasification processes to meet the demands of such applications, but they are expensive to build and operate and consume a significant fraction of overall parasitic energy requirements, thus lowering overall process efficiency. RTI International has developed a warm syngas desulfurization process (WDP) utilizing a transport-bed reactor design and a proprietary attrition-resistant, high-capacity solid sorbent with excellent performance replicated at lab, bench, and pilot scales. Results indicated that WDP technology can improve both efficiency and cost of gasification plants. The WDP technology achieved ~99.9% removal of total sulfur (as either H2S or COS) from coal-derived syngas at temperatures as high as 600°C and over a wide range of pressures (20-80 bar, pressure independent performance) and sulfur concentrations. Based on the success of these tests, RTI negotiated a cooperative agreement with the U.S. Department of Energy for precommercial testing of this technology at Tampa Electric Company’s Polk Power Station IGCC facility in Tampa, Florida. The project scope also included a sweet water-gas-shift process for hydrogen enrichment and an activated amine process for 90+% total carbon capture. Because the activated amine process provides some additional non-selective sulfur removal, the integration of these processes was expected to reduce overall sulfur in the syngas to sub-ppmv concentrations, suitable for most syngas applications. The overall objective of this project was to mitigate the technical risks associated with the scale up and integration of the WDP and carbon dioxide capture technologies, enabling subsequent commercial-scale demonstration. The warm syngas cleanup pre-commercial test unit

  7. Demonstration of a high speed hybrid electrical and optical sensing system for next generation launcher applications

    Science.gov (United States)

    Ibrahim, Selwan K.; O'Dowd, John A.; Honniball, Arthur; Bessler, Vivian; Farnan, Martin; O'Connor, Peter; Melicher, Milos; Gleeson, Danny

    2017-09-01

    The Future Launchers Preparatory Programme (FLPP) supported by the European Space Agency (ESA) has a goal of developing various launch vehicle system concepts and identifying the technologies required for the design of Europe's Next-Generation Launcher (NGL) while maintaining competitiveness on the commercial market. Avionics fiber optic sensing technology was investigated as part of the FLPP programme. Here we demonstrate and evaluate a high speed hybrid electrical/optical data acquisition system based on commercial off the shelf (COTS) technology capable of acquiring data from traditional electrical sensors and optical Fibre Bragg Grating (FBG) sensors. The proposed system consists of the KAM-500 data acquisition system developed by Curtis-Wright and the I4 tunable laser based fiber optic sensor interrogator developed by FAZ Technology. The key objective was to demonstrate the capability of the hybrid system to acquire data from traditional electrical sensors used in launcher applications e.g. strain, temperature and pressure in combination with optical FBG sensors, as well as data delivery to spacecraft avionics systems. The KAM-500 was configured as the main acquisition unit (MAU) and provided a 1 kHz sampling clock to the I4 interrogator that was configured as the secondary acquisition unit (SAU) to synchronize the data acquisition sample rate between both systems. The SAU acquired data from an array of optical FBG sensors, while the MAU data acquisition system acquired data from the electrical sensors. Data acquired from the optical sensors was processed by the FAZ I4 interrogation system and then encapsulated into UDP/IP packets and transferred to the KAM-500. The KAM-500 encapsulated the optical sensor data together with the data acquired from electrical sensors and transmitted the data over MIL-STD-1553 and Ethernet data interface. The temperature measurements resulted in the optical and electrical sensors performing on a par with each other, with all

  8. Demonstration of nuclide migration phenomena in rock on high level irradiation waste geological disposal

    International Nuclear Information System (INIS)

    Kanazawa, Yasuo; Okuyama, Yasuko; Takahashi, Manabu

    1997-01-01

    We have studied on main three theme. From study of material movement in rock-groundwater system in the area of high concentration of irradiative elements, the results proved that minerals with Fe 3+ and clay mineral were very important as mineral held nuclide, the existence of pyrite suggested uranium nuclei enrichment and the latter reduced circumstances, and nuclei movement and accumulation could be estimated from oxidation-reduction potential, kinds of dissolved ions and activity ratio. By study of evaluation of permeability in deep rock fissure system, each measurement method of transmissivity in the Transient Pulse method, the Oscillation test and the Flow Pump method was established. The effect of principle stress, confining pressure, pore water pressure and axial pressure on transmissivity could be determined in the limited level of stress. By study of nuclide migration phenomena and change of rock depend on fissure system, the relation between the degree of change and fissure system was investigated and alternation mineral was identified and it's formation conditions estimated. (S.Y.)

  9. The management of high-level radioactive waste. A survey of demonstration activities

    International Nuclear Information System (INIS)

    1985-04-01

    The following aspects can be only indirectly demonstrated since they involve long periods of time. They have reached the degree of demonstration described below. Prediction of the physical stability of mined cavities at ambient temperatures is well understood from mining experience in salt and hard rocks such as granite. For soft rocks, the stability will depend upon the characteristics of the backfill and structural materials which can be included in predictive models. Normal and abnormal mechanisms for migration of radionuclides from repositories have been generally identified. Which of these mechanisms are relevant for the future evolution of a repository system depends on the repository site. Techniques for closure and sealing of repositories have been demonstrated, but validation of their long-term performance is lacking. The ability to construct mathematical models that predict repository and environmental behaviour over long periods of the future is now conceptually demonstrated. Some of these models are very sophisticated, but confidence is growing in their predictions. The reliability of results has been demonstrated, in some cases, by intercomparison of different modelling techniques; however, in many instances the models need validation. Generic data in support of models may, in many respects, be adequate. More data, and therefore R and D efforts concentrating on specific sites, are required to assist in the validation of some aspects of model predictions against the real world. This is an aspect of demonstration that continues to be necessary and is being pursued

  10. Demonstration of the frequency modulation of optical signals with a high frequency deviation parameter

    International Nuclear Information System (INIS)

    Shamray, A V; Kozlov, A S; Il'ichev, I V; Petrov, M P

    2008-01-01

    A new type of an integrated optical modulator for the frequency coding of optical signals is developed and fabricated. The modulator operation is based on the original technology of the electric control of a Bragg grating. The frequency modulation of an optical signal with the frequency deviation of 25 GHz is demonstrated experimentally. The modular was used to transfer the ASCII code through an optical fibre. (optical communication)

  11. Demonstrated high performance of gas-filled rugby-shaped hohlraums on Omega

    Energy Technology Data Exchange (ETDEWEB)

    Philippe, F.; Villette, B. [CEA, DAM, DIF, F-91297 Arpajon (France); Michel, P. [Lawrence Livermore National Laboratory, Livermore, California 94550 (United States); Petrasso, R. [Plasma Science and Fusion Center, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139 (United States); Stoeckl, C. [Laboratory for Laser Energetics, University of Rochester, Rochester, New York 14623 (United States); Giraldez, E. [General Atomics, P.O. Box 85608, San Diego, California 92186-5608 (United States); Tassin, V.; Depierreux, S.; Gauthier, P.; Masson-Laborde, P. E.; Monteil, M. C.; Seytor, P.; Lasinski, B.; Park, H. S.; Ross, J. S.; Amendt, P.; Döppner, T.; Hinkel, D. E.; Wallace, R.; Williams, E.; and others

    2014-07-15

    A direct experimental comparison of rugby-shaped and cylindrical shaped gas-filled hohlraums on the Omega laser facility demonstrates that higher coupling and minimal backscatter can be achieved in the rugby geometry, leading to significantly enhanced implosion performance. A nearly 50% increase of x-ray drive is associated with earlier bangtime and increase of neutron production. The observed drive enhancement from rugby geometry in this study is almost twice stronger than in previously published results.

  12. Demonstrated high performance of gas-filled rugby-shaped hohlraums on Omega

    Science.gov (United States)

    Philippe, F.; Tassin, V.; Depierreux, S.; Gauthier, P.; Masson-Laborde, P. E.; Monteil, M. C.; Seytor, P.; Villette, B.; Lasinski, B.; Park, H. S.; Ross, J. S.; Amendt, P.; Döppner, T.; Hinkel, D. E.; Wallace, R.; Williams, E.; Michel, P.; Frenje, J.; Gatu-Johnson, M.; Li, C. K.; Petrasso, R.; Glebov, V.; Sorce, C.; Stoeckl, C.; Nikroo, A.; Giraldez, E.

    2014-07-01

    A direct experimental comparison of rugby-shaped and cylindrical shaped gas-filled hohlraums on the Omega laser facility demonstrates that higher coupling and minimal backscatter can be achieved in the rugby geometry, leading to significantly enhanced implosion performance. A nearly 50% increase of x-ray drive is associated with earlier bangtime and increase of neutron production. The observed drive enhancement from rugby geometry in this study is almost twice stronger than in previously published results.

  13. Demonstrated high performance of gas-filled rugby-shaped hohlraums on Omega

    International Nuclear Information System (INIS)

    Philippe, F.; Villette, B.; Michel, P.; Petrasso, R.; Stoeckl, C.; Giraldez, E.; Tassin, V.; Depierreux, S.; Gauthier, P.; Masson-Laborde, P. E.; Monteil, M. C.; Seytor, P.; Lasinski, B.; Park, H. S.; Ross, J. S.; Amendt, P.; Döppner, T.; Hinkel, D. E.; Wallace, R.; Williams, E.

    2014-01-01

    A direct experimental comparison of rugby-shaped and cylindrical shaped gas-filled hohlraums on the Omega laser facility demonstrates that higher coupling and minimal backscatter can be achieved in the rugby geometry, leading to significantly enhanced implosion performance. A nearly 50% increase of x-ray drive is associated with earlier bangtime and increase of neutron production. The observed drive enhancement from rugby geometry in this study is almost twice stronger than in previously published results

  14. Demonstrated high performance of gas-filled rugby-shaped hohlraums on Omega

    Energy Technology Data Exchange (ETDEWEB)

    Philippe, F. [Commissariat a l' Energie Atomique et aux Energies Alternatives (CEA), Arpajon (France); Tassin, V. [Commissariat a l' Energie Atomique et aux Energies Alternatives (CEA), Arpajon (France); Depierreux, S. [Commissariat a l' Energie Atomique et aux Energies Alternatives (CEA), Arpajon (France); Gauthier, P. [Commissariat a l' Energie Atomique et aux Energies Alternatives (CEA), Arpajon (France); Masson-Laborde, P. E. [Commissariat a l' Energie Atomique et aux Energies Alternatives (CEA), Arpajon (France); Monteil, M. C. [Commissariat a l' Energie Atomique et aux Energies Alternatives (CEA), Arpajon (France); Seytor, P. [Commissariat a l' Energie Atomique et aux Energies Alternatives (CEA), Arpajon (France); Villette, B. [Commissariat a l' Energie Atomique et aux Energies Alternatives (CEA), Arpajon (France); Lasinski, B. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Park, H. S. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Ross, J. S. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Amendt, P. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Doeppner, T. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Hinkel, D. E. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Wallace, R. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Williams, E. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Michel, P. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Frenje, J. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States). Plasma Science and Fusion Center; Gatu-Johnson, M. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States). Plasma Science and Fusion Center; Li, C. K. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States). Plasma Science and Fusion Center; Petrasso, R. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States). Plasma Science and Fusion Center; Glebov, V. [Univ. of Rochester, NY (United States). Lab. for Laser Energetics; Sorce, C. [Univ. of Rochester, NY (United States). Lab. for Laser Energetics; Stoeckl, C. [Univ. of Rochester, NY (United States). Lab. for Laser Energetics; Nikroo, A. [General Atomics, San Diego, CA (United States); Giraldez, E. [General Atomics, San Diego, CA (United States)

    2014-07-25

    A direct experimental comparison of rugby-shaped and cylindrical shaped gas-filled hohlraums on the Omega laser facility demonstrates that higher coupling and minimal backscatter can be achieved in the rugby geometry, leading to significantly enhanced implosion performance. A nearly 50% increase of x-ray drive is associated with earlier bangtime and increase of neutron production. The observed drive enhancement from rugby geometry in this study is almost twice stronger than in previously published results.

  15. Four High-Visibility Enforcement Demonstration Waves in Connecticut and New York Reduce Hand-Held Phone Use

    Science.gov (United States)

    2011-07-01

    The National Highway Traffic : Safety Administration initiated : distracted driving demonstration : programs in two communities : to test whether a high-visibility : enforcement (HVE) model could : reduce two specific instances : of distracted drivin...

  16. Conditional High-Order Boltzmann Machines for Supervised Relation Learning.

    Science.gov (United States)

    Huang, Yan; Wang, Wei; Wang, Liang; Tan, Tieniu

    2017-09-01

    Relation learning is a fundamental problem in many vision tasks. Recently, high-order Boltzmann machine and its variants have shown their great potentials in learning various types of data relation in a range of tasks. But most of these models are learned in an unsupervised way, i.e., without using relation class labels, which are not very discriminative for some challenging tasks, e.g., face verification. In this paper, with the goal to perform supervised relation learning, we introduce relation class labels into conventional high-order multiplicative interactions with pairwise input samples, and propose a conditional high-order Boltzmann Machine (CHBM), which can learn to classify the data relation in a binary classification way. To be able to deal with more complex data relation, we develop two improved variants of CHBM: 1) latent CHBM, which jointly performs relation feature learning and classification, by using a set of latent variables to block the pathway from pairwise input samples to output relation labels and 2) gated CHBM, which untangles factors of variation in data relation, by exploiting a set of latent variables to multiplicatively gate the classification of CHBM. To reduce the large number of model parameters generated by the multiplicative interactions, we approximately factorize high-order parameter tensors into multiple matrices. Then, we develop efficient supervised learning algorithms, by first pretraining the models using joint likelihood to provide good parameter initialization, and then finetuning them using conditional likelihood to enhance the discriminant ability. We apply the proposed models to a series of tasks including invariant recognition, face verification, and action similarity labeling. Experimental results demonstrate that by exploiting supervised relation labels, our models can greatly improve the performance.

  17. A proposed high-power UV industrial demonstration laser at CEBAF

    International Nuclear Information System (INIS)

    Benson, S.V.; Bisognano, J.J.; Bohn, C.L.

    1996-01-01

    The Laser Processing Consortium, a collaboration of industries, universities, and the Continuous Electron Beam Accelerator Facility (CEBAF) in Newport News, Virginia, has proposed building a demonstration industrial processing laser for surface treatment and micro-machining. The laser is a free-electron laser (FEL) with average power output exceeding 1 kW in the ultraviolet (UV). The design calls for a novel driver accelerator that recovers most of the energy of the exhaust electron beam to produce laser light with good wall-plug efficiency. The laser and accelerator design use technologies that are scalable to much higher power. The authors describe the critical design issues in the laser such as the stability, power handling, and losses of the optical resonator, and the quality, power, and reliability of the electron beam. They also describe the calculated laser performance. Finally progress to date on accelerator development and resonator modeling will be reported

  18. A proposed high-power UV industrial demonstration laser at CEBAF

    International Nuclear Information System (INIS)

    Benson, S.V.; Bisognano, J.J.; Bohn, C.L.

    1996-01-01

    The Laser Processing Consortium, a collaboration of industries, universities, and the Continuous Electron Beam Accelerator Facility (CEBAF) in Newport News, Virginia, has proposed building a demonstration industrial processing laser for surface treatment and micro-machining. The laser is a free-electron laser (FEL) with average power output exceeding 1 kW in the ultraviolet (UV). The design calls for a novel driver accelerator that recovers most of the energy of the exhaust electron beam to produce laser light with good wall-plug efficiency. The laser and accelerator design use technologies that are scalable to much higher power. The authors will describe the critical design issues in the laser such as the stability, power handling, and losses of the optical resonator, and the quality, power, and reliability of the electron beam. They will also describe the calculated laser performance. Finally progress to date on accelerator development and resonator modeling will be reported

  19. An investigation of the influence of reconceptualization of demonstrative experimental activities of optics in high school

    Directory of Open Access Journals (Sweden)

    Jair Lúcio Prados Ribeiro

    2013-08-01

    Full Text Available In this work, we analyze the influence that the use of demonstrative experiments can bring to the learning of optics. It is assumed that the development of experimental activities, when reconceptualized according to Hodson proposal, tends to contribute to the generation of cognitive conflicts when compared to traditional didactic experience. Justifications are given for an analysis of changes under a Piagetian bias, reconciled with Hodson proposal. The methodology used to structure the topics presentations was quasi-experimental, contrasting an experimental group with a control group. The measuring of the effectiveness of the suggested working method was made from a quantitative analysis, which identified some of the topics discussed had better results in learning, being more tied to the experiments carried out.

  20. Experimental demonstration of a compact epithermal neutron source based on a high power laser

    Science.gov (United States)

    Mirfayzi, S. R.; Alejo, A.; Ahmed, H.; Raspino, D.; Ansell, S.; Wilson, L. A.; Armstrong, C.; Butler, N. M. H.; Clarke, R. J.; Higginson, A.; Kelleher, J.; Murphy, C. D.; Notley, M.; Rusby, D. R.; Schooneveld, E.; Borghesi, M.; McKenna, P.; Rhodes, N. J.; Neely, D.; Brenner, C. M.; Kar, S.

    2017-07-01

    Epithermal neutrons from pulsed-spallation sources have revolutionised neutron science allowing scientists to acquire new insight into the structure and properties of matter. Here, we demonstrate that laser driven fast (˜MeV) neutrons can be efficiently moderated to epithermal energies with intrinsically short burst durations. In a proof-of-principle experiment using a 100 TW laser, a significant epithermal neutron flux of the order of 105 n/sr/pulse in the energy range of 0.5-300 eV was measured, produced by a compact moderator deployed downstream of the laser-driven fast neutron source. The moderator used in the campaign was specifically designed, by the help of MCNPX simulations, for an efficient and directional moderation of the fast neutron spectrum produced by a laser driven source.

  1. A Useful Demonstration of Calculus in a Physics High School Laboratory

    Science.gov (United States)

    Alvarez, Gustavo; Schulte, Jurgen; Stockton, Geoffrey; Wheeler, David

    2018-01-01

    The real power of calculus is revealed when it is applied to actual physical problems. In this paper, we present a calculus inspired physics experiment suitable for high school and undergraduate programs. A model for the theory of the terminal velocity of a falling body subject to a resistive force is developed and its validity tested in an…

  2. Preconceptual design study for solidifying high-level waste: West Valley Demonstration Project

    International Nuclear Information System (INIS)

    Hill, O.F.

    1981-04-01

    This report presents a preconceptual design study for processing radioactive high-level liquid waste presently stored in underground tanks at Western New York Nuclear Service Center (WNYNSC) near West Valley, New York, and for incorporating the radionculides in that waste into a solid. The high-level liquid waste accumulated from the operation of a chemical reprocessing plant by the Nuclear Fuel Services, Inc. from 1966 to 1972. The high-level liquid waste consists of approximately 560,000 gallons of alkaline waste from Purex process operations and 12,000 gallons of acidic (nitric acid) waste from one campaign of processing thoria fuels by a modified Thorex process (during this campaign thorium was left in the waste). The alkaline waste contains approximately 30 million curies and the acidic waste contains approximately 2.5 million curies. The reference process described in this report is concerned only with chemically processing the high-level liquid waste to remove radionuclides from the alkaline supernate and converting the radionuclide-containing nonsalt components in the waste into a borosilicate glass

  3. Demonstration Of 3D Effects With High Gain And Efficiency In A UV FEL Oscillator

    International Nuclear Information System (INIS)

    Benson, Stephen; Biallas, George; Blackburn, Keith; Boyce, James; Bullard, Donald; Coleman, James; Dickover, Cody; Douglas, David; Ellingsworth, Forrest; Evtushenko, Pavel; Hernandez-Garcia, Carlos; Gould, Christopher; Gubeli, Joseph; Hardy, David; Jordan, Kevin; Klopf, John; Kortze, James; Legg, Robert; Marchlik, Matthew; Moore, Steven; Neil, George; Powers, Thomas; Sexton, Daniel; Shinn, Michelle; Tennant, Christopher; Walker, Richard; Watson, Anne; Williams, Gwyn; Wilson, Frederick; Zhang, Shukui

    2011-01-01

    We report on the performance of a high gain UV FEL oscillator operating on an energy recovery linac at Jefferson Lab. The high brightness of the electron beam leads to both gain and efficiency that cannot be reconciled with a one-dimensional model. Three-dimensional simulations do predict the performance with reasonable precision. Gain in excess of 100% per pass and an efficiency close to 1/2NW, where NW is the number of wiggler periods, is seen. The laser mirror tuning curves currently permit operation in the wavelength range of 438 to 362 nm. Another mirror set allows operation at longer wavelengths in the red with even higher gain and efficiency.

  4. Demonstration of high performance negative central magnetic shear discharges on the DIII-D tokamak

    International Nuclear Information System (INIS)

    Rice, B.W.; Burrell, K.H.; Lao, L.L.

    1996-01-01

    Reliable operation of discharges with negative central magnetic shear has led to significant increases in plasma performance and reactivity in both low confinement, L-mode, and high confinement, H-mode, regimes in the DIII-D tokamak. Using neutral beam injection early in the initial current ramp, a large range of negative shear discharges have been produced with durations lasting up to 3.2 s. The total non- inductive current (beam plus bootstrap) ranges from 50% to 80% in these discharges. In the region of shear reversal, significant peaking of the toroidal rotation [f φ ∼ 30-60 kHz] and ion temperature [T i (0) ∼ 15-22 keV] profiles are observed. In high power discharges with an L-mode edge, peaked density profiles are also observed. Confinement enhancement factors up to H ≡ τ E /τ ITER-89P ∼ 2.5 with an L-mode edge, and H ∼ 3.3 in an Edge Localized Mode (ELM)-free H-mode, are obtained. Transport analysis shows both ion thermal diffusivity and particle diffusivity to be near or below standard neoclassical values in the core. Large pressure peaking in L- mode leads to high disruptivity with Β N ≡ Β T /(I/aB) ≤ 2.3, while broader pressure profiles in H- mode gives low disruptivity with Β N ≤ 4.2

  5. Demonstration of high efficiency intermediate-temperature solid oxide fuel cell based on lanthanum gallate electrolyte

    International Nuclear Information System (INIS)

    Inagaki, Toru; Nishiwaki, Futoshi; Kanou, Jirou; Yamasaki, Satoru; Hosoi, Kei; Miyazawa, Takashi; Yamada, Masaharu; Komada, Norikazu

    2006-01-01

    The Kansai Electric Power Co., Inc. (KEPCO) and Mitsubishi Materials Corporation (MMC) have been jointly developing intermediate-temperature solid oxide fuel cells (SOFCs). The operation temperatures between 600 and 800 o C were set as the target, which enable SOFC to use less expensive metallic separators for cell-stacking and to carry out internal reforming of hydrocarbon fuels. The electrolyte-supported planar-type cells were fabricated using highly conductive lanthanum gallate-based electrolyte, La(Sr)Ga(Mg,Co)O 3-δ , Ni-(CeO 2 ) 1-x (SmO 1.5 ) x cermet anode, and Sm(Sr)CoO 3-δ cathode. The 1 kW-class power generation modules were fabricated using a seal-less stack of the cells and metallic separators. The 1 kW-class prototype power generation system with the module was developed with the high performance cell, which showed the thermally self-sustainability. The system included an SOFC module, a dc-ac inverter, a desulfurizer, and a heat recovery unit. It provided stable ac power output of 1 kW with the electrical efficiency of 45% LHV based on ac output by using city gas as a fuel, which was considered to be excellent for such a small power generation system. And the hot water of 90 o C was obtained using high temperature off-gas from SOFC

  6. Demonstration of high efficiency intermediate-temperature solid oxide fuel cell based on lanthanum gallate electrolyte

    Energy Technology Data Exchange (ETDEWEB)

    Inagaki, Toru [Kansai Electric Power Co. Inc., Energy Use R and D Center, 11-20 Nakoji 3-chome, Amagasaki, Hyogo 661-0974 (Japan)]. E-mail: inagaki@rdd.kepco.co.jp; Nishiwaki, Futoshi [Kansai Electric Power Co. Inc., Energy Use R and D Center, 11-20 Nakoji 3-chome, Amagasaki, Hyogo 661-0974 (Japan); Kanou, Jirou [Kansai Electric Power Co. Inc., Energy Use R and D Center, 11-20 Nakoji 3-chome, Amagasaki, Hyogo 661-0974 (Japan); Yamasaki, Satoru [Kansai Electric Power Co. Inc., Energy Use R and D Center, 11-20 Nakoji 3-chome, Amagasaki, Hyogo 661-0974 (Japan); Hosoi, Kei [Mitsubishi Materials Corporation, Central Research Institute, 1002-14 Mukohyama, Naka-machi, Naka-gun, Ibaraki 311-0102 (Japan); Miyazawa, Takashi [Mitsubishi Materials Corporation, Central Research Institute, 1002-14 Mukohyama, Naka-machi, Naka-gun, Ibaraki 311-0102 (Japan); Yamada, Masaharu [Mitsubishi Materials Corporation, Central Research Institute, 1002-14 Mukohyama, Naka-machi, Naka-gun, Ibaraki 311-0102 (Japan); Komada, Norikazu [Mitsubishi Materials Corporation, Central Research Institute, 1002-14 Mukohyama, Naka-machi, Naka-gun, Ibaraki 311-0102 (Japan)

    2006-02-09

    The Kansai Electric Power Co., Inc. (KEPCO) and Mitsubishi Materials Corporation (MMC) have been jointly developing intermediate-temperature solid oxide fuel cells (SOFCs). The operation temperatures between 600 and 800 {sup o}C were set as the target, which enable SOFC to use less expensive metallic separators for cell-stacking and to carry out internal reforming of hydrocarbon fuels. The electrolyte-supported planar-type cells were fabricated using highly conductive lanthanum gallate-based electrolyte, La(Sr)Ga(Mg,Co)O{sub 3-{delta}}, Ni-(CeO{sub 2}){sub 1-x}(SmO{sub 1.5}) {sub x} cermet anode, and Sm(Sr)CoO{sub 3-{delta}} cathode. The 1 kW-class power generation modules were fabricated using a seal-less stack of the cells and metallic separators. The 1 kW-class prototype power generation system with the module was developed with the high performance cell, which showed the thermally self-sustainability. The system included an SOFC module, a dc-ac inverter, a desulfurizer, and a heat recovery unit. It provided stable ac power output of 1 kW with the electrical efficiency of 45% LHV based on ac output by using city gas as a fuel, which was considered to be excellent for such a small power generation system. And the hot water of 90 {sup o}C was obtained using high temperature off-gas from SOFC.

  7. Performance demonstration of a high-power space-reactor heat-pipe design

    International Nuclear Information System (INIS)

    Merrigan, M.A.; Martinez, E.H.; Keddy, E.S.; Runyan, J.; Kemme, J.E.

    1983-01-01

    Performance of a 15.9-mm diam, 2-m long, artery heat pipe has been demonstrated at power levels to 22.6 kW and temperatures to 1500 0 K. The heat pipe employed lithium as a working fluid with distribution wicks and arteries fabricated from 400 mesh Mo-41 wt % Re screen. Molybdenum alloy (TZM) was used for the container. Peak axial power density attained in the testing was 19 kW/cm 2 at 1465 0 K. The corresponding radial flux density in the evaporator region of the heat pipe was 150 W/cm 2 . The extrapolated limit for the heat pipe at its 1500 0 K design point is 30 kW, corresponding to an axial flux density of 25 kW/cm 2 . Sonic and capillary limits for the design were investigated in the 1100 to 1500 0 K temperature range. Excellent agreement of measured and predicted temperature and power levels was observed

  8. Demonstration of Millimeter Wave 5G Setup Employing High-Gain Vivaldi Array

    Directory of Open Access Journals (Sweden)

    Waleed Tariq Sethi

    2018-01-01

    Full Text Available We present a 4 × 4 slot-coupled Vivaldi antenna (SCVA array unit cell, which offers wide bandwidth and high gain (~23 dBi at the millimeter wave (mmW frequencies of 28 GHz and 38 GHz. A single SCVA element is first presented, which has a bandwidth of 25–40 GHz with an average gain of ~13 dBi at the frequencies of interest. This antenna element is then used to design a 1 × 4 linear SCVA array matched to a 50 Ω impedance via a modified Wilkinson power divider (WPD. Next, the 1 × 4 linear array is used to construct a 4 × 4 antenna array unit cell. The proposed 4 × 4 antenna array unit cell is fabricated, and the characteristics of its elements (i.e., the single SCVA, 1 × 4 linear array, and WPD are thoroughly investigated. Further, the 4 × 4 array is tested for signal reception of various digital modulation formats at lab environment using high-speed digital signal oscilloscope. In particular, a 2.5 Gbps data rate is successfully transmitted achieving receiver sensitivity of −50 dBm at 2 × 10−3 bit error rate (BER for 32 quadrature amplitude modulation (QAM with a system baud rate of 500 MHz. The wide bandwidth and high gain along with the excellent performance of the proposed 4 × 4 antenna array unit cell makes it an excellent candidate for future 5G wireless communication applications.

  9. Product Stewardship in Uranium: A Way for the Industry to Demonstrate its High Performance

    International Nuclear Information System (INIS)

    Harris, Frank

    2014-01-01

    Conclusions: • Product stewardship is an means for communicating the high performance on health, safety and environment of the nuclear fuel cycle including uranium mining. • It has been effective with other products and is appropriate for uranium. • Can be a vehicle for addressing public concerns across the industry. • Due to uranium’s unique characteristics it has the potential to be a best practice example of product stewardship. • Work is underway in the international arena to progress uranium product stewardship and it represent a unique opportunity to provide whole of industry benefits

  10. A useful demonstration of calculus in a physics high school laboratory

    Science.gov (United States)

    Alvarez, Gustavo; Schulte, Jurgen; Stockton, Geoffrey; Wheeler, David

    2018-01-01

    The real power of calculus is revealed when it is applied to actual physical problems. In this paper, we present a calculus inspired physics experiment suitable for high school and undergraduate programs. A model for the theory of the terminal velocity of a falling body subject to a resistive force is developed and its validity tested in an experiment of a falling magnet in a column of self-induced eddy currents. The presented method combines multiple physics concepts such as 1D kinematics, classical mechanics, electromagnetism and non-trivial mathematics. It offers the opportunity for lateral as well as project-based learning.

  11. Demonstration of high temperature thermoelectric waste heat recovery from exhaust gases of a combustion engine

    Energy Technology Data Exchange (ETDEWEB)

    Trottmann, Matthias; Weidenkaff, Anke; Populoh, Sascha; Brunko, Oliver; Veziridis, Angelika; Bach, Christian; Cabalzar, Urs [Empa, Duebendorf (Switzerland)

    2011-07-01

    The energy efficiency of passenger cars becomes increasingly important due to a growing awareness in terms of climate change and shortages of resources associated with rising fuel prices. In addition to the efforts towards the optimization of the engine's internal efficiency, waste heat recovery is the main objective. In this respect, thermoelectric (TE) devices seem to be suited as heat recuperation systems. Thermoelectric generators allow for direct transformation of thermal into electrical energy. In order to thoroughly investigate this type of recovery system a TE demonstrator was mounted on the muffler of a VW Touran and tested. The waste heat of the exhaust gas was converted into electricity with a conversion rate of {proportional_to}. 3.5%. The limiting factor was the low thermal stability of the commercial modules used in this pre-study to elaborate reference values. Thermoelectric modules based on sustainable and temperature-stable materials are being developed to improve the measured values. A thermoelectric test generator with perovskite-type oxide modules was constructed confirm the function and stability at elevated temperatures. Despite all the advantages of this material class, the TE performance is still to be improved. A quantitative measure of a material's TE performance is the temperature-independent Figure of Merit ZT. ZT increases with decreasing thermal and increasing electrical conductivity. An approach to thermal conductivity reduction is nanostructuring of the material. The Ultrasonic Spray Combustion (USC) technique allows to produce powders with a grain size on the nanoscale and was tested in this study. (orig.)

  12. Examining the Features of Earth Science Logical Reasoning and Authentic Scientific Inquiry Demonstrated in a High School Earth Science Curriculum: A Case Study

    Science.gov (United States)

    Park, Do-Yong; Park, Mira

    2013-01-01

    The purpose of this study was to investigate the inquiry features demonstrated in the inquiry tasks of a high school Earth Science curriculum. One of the most widely used curricula, Holt Earth Science, was chosen for this case study to examine how Earth Science logical reasoning and authentic scientific inquiry were related to one another and how…

  13. HAW project. Demonstrative disposal of high-level radioactive wastes in the Asse salt mine

    International Nuclear Information System (INIS)

    Rothfuchs, T.; Duijves, K.; Stippler, R.

    1988-01-01

    Since 1968 the GSF has been carrying out research and development programs for the final disposal of high-level radioactive waste (HAW) in salt formations. The heat producing waste has been simulated so far by means of electrical heaters and also cobalt-60-sources. In order to improve the final concept for HAW disposal in salt formations the complete technical system of an underground repository is to be tested in an one-to-one scale test facility. To satisfy the test objectives thirty high radioactive canisters containing the radionuclides Cs-137 and Sr-90 will be emplaced in six boreholes located in two test galleries at the 800 m-level in the Asse salt mine. The duration of testing will be approximately five years. For the handling of the radioactive canisters and their emplacement into the boreholes a system consisting of transportation casks, transportation vehicle, disposal machine, and borehole slider will be developed and tested. The actual scientific investigation program is based on the estimation and observation of the interaction between the radioactive canisters and the rock salt. This program includes measurement of thermally and radiolytically induced water and gas release from the rock salt and the radiolytical decomposition of salt minerals. Also the thermally induced stress and deformation fields in the surrounding rock mass will be investigated carefully. The project is funded by the BMFT and the CEC and carrier out in close co-operation with the Netherlands Energy Research Foundation (ECN)

  14. The HAW project. Demonstrative disposal of high-level radioactive wastes in the Asse salt mine

    International Nuclear Information System (INIS)

    Rothfuchs, T.; Duijves, K.

    1988-04-01

    Since 1968 the GSF has been carrying out research and development programs for the final disposal of high-level radioactive waste (HAW) in salt formations. The heat producing waste has been simulated so far by means of electrical heaters and also cobalt-60-sources. In order to improve the final concept for HAW disposal in salt formations the complete technical system of an underground repository is to be tested in a one-to-one scale test facility. To satisfy the test objectives thirty high radioactive canisters containing the radionuclides Cs-137 and Sr-90 will be emplaced in six boreholes located in two test galleries at the 800 m-level in the Asse salt mine. The duration of testing will be approximately five years. For the handling of the radioactive canisters and their emplacement into the boreholes a system consisting of transportation casks, transportation vehicle, disposal machine, and borehole slider will be developed and tested. The actual scientific investigation program is based on the estimation and observation of the interaction between the radioactive canisters and the rock salt. This program includes measurement of thermally and radiolytically induced water and gas release from the rock salt and the radiolytical decomposition of salt minerals. Also the thermally induced stress and deformation fields in the surrounding rock mass will be investigated carefully. (orig./HP)

  15. First demonstration report on the high temperature materials data Bank of JRC

    International Nuclear Information System (INIS)

    1983-01-01

    The High Temperature Materials Programme of the Joint Research Centre has among its activities a project which has the objective to develop a computerised data bank containing mechanical property data of alloys for high temperature applications. The pilot phase of this project during the multiannual programme 1980-1983 is restricted to a few alloys and properties. The present scope comprises tensile, creep and fatigue test results with emphasis on 600-1000 0 C test temperature and C-O-H environments for alloys covered by the specifications of the ''Alloy 800'' group. The data bank is now operational. This report is the first presentation of the data bank characteristics, contents and some output illustrations. It contains a descriptive part on the system and its structure and on the characteristics and quantity of the present data, and an illustrative part showing examples of data bank processed output. The selected print-outs are generated by interactive on-line searches and subsequent numerical or graphical processing in the data bank facilities at Petten and Ispra which are linked by EURONET

  16. The HAW-project: Demonstration facility for the disposal of high-level waste in salt

    International Nuclear Information System (INIS)

    Rothfuchs, T.; Duijves, K.A.; Mueller-Lyda, I.

    1990-04-01

    To satisfy the test objectives thirty highly radioactive canisters containing the radionuclides Cs-137 and Sr-90 will be emplaced in six boreholes located in two test galleries at the 800 m-level in the Asse salt mine. For handling of the radioactive canisters and their emplacement into the boreholes a system consisting of a transport cask, a transport vehicle, a disposal machine, and of a borehole slider has been developed. The actual scientific investigation programme is based on the estimation and observation of the interaction between the radioactive canisters and the rock salt. This programme includes measurement of thermally and radiolytically induced water and gas release from the rock salt and the radiolytical decomposition of salt minerals. Also the thermally induced stress and deformation fields in the surrounding rock mass will be investigated carefully. (orig./DG)

  17. Fluoride Salt-Cooled High-Temperature Reactor Technology Development and Demonstration Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    Holcomb, David Eugene [ORNL; Flanagan, George F [ORNL; Mays, Gary T [ORNL; Pointer, William David [ORNL; Robb, Kevin R [ORNL; Yoder Jr, Graydon L [ORNL

    2013-11-01

    Fluoride salt-cooled High-temperature Reactors (FHRs) are an emerging reactor class with potentially advantageous performance characteristics, and fully passive safety. This roadmap describes the principal remaining FHR technology challenges and the development path needed to address the challenges. This roadmap also provides an integrated overview of the current status of the broad set of technologies necessary to design, evaluate, license, construct, operate, and maintain FHRs. First-generation FHRs will not require any technology breakthroughs, but do require significant concept development, system integration, and technology maturation. FHRs are currently entering early phase engineering development. As such, this roadmap is not as technically detailed or specific as would be the case for a more mature reactor class. The higher cost of fuel and coolant, the lack of an approved licensing framework, the lack of qualified, salt-compatible structural materials, and the potential for tritium release into the environment are the most obvious issues that remain to be resolved.

  18. Combined Heat and Power Systems Technology Development and Demonstration 370 kW High Efficiency Microturbine

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2015-10-14

    The C370 Program was awarded in October 2010 with the ambitious goal of designing and testing the most electrically efficient recuperated microturbine engine at a rated power of less than 500 kW. The aggressive targets for electrical efficiency, emission regulatory compliance, and the estimated price point make the system state-of-the-art for microturbine engine systems. These goals will be met by designing a two stage microturbine engine identified as the low pressure spool and high pressure spool that are based on derivative hardware of Capstone’s current commercially available engines. The development and testing of the engine occurred in two phases. Phase I focused on developing a higher power and more efficient engine, that would become the low pressure spool which is based on Capstone’s C200 (200kW) engine architecture. Phase II integrated the low pressure spool created in Phase I with the high pressure spool, which is based on Capstone’s C65 (65 kW) commercially available engine. Integration of the engines, based on preliminary research, would allow the dual spool engine to provide electrical power in excess of 370 kW, with electrical efficiency approaching 42%. If both of these targets were met coupled with the overall CHP target of 85% total combined heating and electrical efficiency California Air Resources Board (CARB) level emissions, and a price target of $600 per kW, the system would represent a step change in the currently available commercial generation technology. Phase I of the C370 program required the development of the C370 low pressure spool. The goal was to increase the C200 engine power by a minimum of 25% — 250 kW — and efficiency from 32% to 37%. These increases in the C200 engine output were imperative to meet the power requirements of the engine when both spools were integrated. An additional benefit of designing and testing the C370 low pressure spool was the possibility of developing a stand-alone product for possible

  19. ARC: A compact, high-field, fusion nuclear science facility and demonstration power plant with demountable magnets

    Energy Technology Data Exchange (ETDEWEB)

    Sorbom, B.N., E-mail: bsorbom@mit.edu; Ball, J.; Palmer, T.R.; Mangiarotti, F.J.; Sierchio, J.M.; Bonoli, P.; Kasten, C.; Sutherland, D.A.; Barnard, H.S.; Haakonsen, C.B.; Goh, J.; Sung, C.; Whyte, D.G.

    2015-11-15

    Highlights: • ARC reactor designed to have 500 MW fusion power at 3.3 m major radius. • Compact, simplified design allowed by high magnetic fields and jointed magnets. • ARC has innovative plasma physics solutions such as inboardside RF launch. • High temperature superconductors allow high magnetic fields and jointed magnets. • Liquid immersion blanket and jointed magnets greatly simplify tokamak reactor design. - Abstract: The affordable, robust, compact (ARC) reactor is the product of a conceptual design study aimed at reducing the size, cost, and complexity of a combined fusion nuclear science facility (FNSF) and demonstration fusion Pilot power plant. ARC is a ∼200–250 MWe tokamak reactor with a major radius of 3.3 m, a minor radius of 1.1 m, and an on-axis magnetic field of 9.2 T. ARC has rare earth barium copper oxide (REBCO) superconducting toroidal field coils, which have joints to enable disassembly. This allows the vacuum vessel to be replaced quickly, mitigating first wall survivability concerns, and permits a single device to test many vacuum vessel designs and divertor materials. The design point has a plasma fusion gain of Q{sub p} ≈ 13.6, yet is fully non-inductive, with a modest bootstrap fraction of only ∼63%. Thus ARC offers a high power gain with relatively large external control of the current profile. This highly attractive combination is enabled by the ∼23 T peak field on coil achievable with newly available REBCO superconductor technology. External current drive is provided by two innovative inboard RF launchers using 25 MW of lower hybrid and 13.6 MW of ion cyclotron fast wave power. The resulting efficient current drive provides a robust, steady state core plasma far from disruptive limits. ARC uses an all-liquid blanket, consisting of low pressure, slowly flowing fluorine lithium beryllium (FLiBe) molten salt. The liquid blanket is low-risk technology and provides effective neutron moderation and shielding, excellent

  20. Demonstration of innovative partitioning processes for minor actinide recycling from high active waste solutions

    International Nuclear Information System (INIS)

    Modolo, G.; Wilden, A.; Geist, A.; Malmbeck, R.; Taylor, R.

    2014-01-01

    The recycling of the minor actinides (MA) using the Partitioning and Transmutation strategy (P and T) could contribute significantly to reducing the volume of high level waste in a geological repository and to decreasing the waste's longterm hazards originating from the long half-life of the actinides. Several extraction processes have been developed worldwide for the separation and recovery of MA from highly active raffinates (HAR, e.g. the PUREX raffinate). A multi-cycle separation strategy has been developed within the framework of European collaborative projects. The multi-cycle processes, on the one hand, make use of different extractants for every single process. Within the recent FP7 European research project ACSEPT (Actinide reCycling by SEParation and Transmutation), the development of new innovative separation processes with a reduced number of cycles was envisaged. In the so-called 'innovative SANEX' concept, the trivalent actinides and lanthanides are co-extracted from the PUREX raffinate by a DIAMEX like process (e.g. TODGA). Then, the loaded solvent is subjected to several stripping steps. The first one concerns selectively stripping the actinides(III) with selective water-soluble ligands (SO3-Ph-BTB), followed by the subsequent stripping of trivalent lanthanides. A more challenging route studied also within our laboratories is the direct actinide(III) separation from a PUREX-type raffinate using a mixture of CyMe 4 BTBP and TODGA as extractants, the so-called One cycle SANEX process. A new approach, which was also studied within the ACSEPT project, is the GANEX (Grouped ActiNide EXtraction) concept addressing the simultaneous partitioning of all transuranium (TRU) elements for their homogeneous recycling in advanced generation IV reactor systems. Bulk uranium is removed in the GANEX 1st cycle, e.g. using a monoamide extractant and the GANEX 2nd cycle then separates the TRU. A solvent composed of TODGA + DMDOHEMA in kerosene has been shown to

  1. Demonstration of high coupling efficiency to Al capsule in rugby hohlraum on NIF

    Science.gov (United States)

    Ping, Y.; Smalyuk, V.; Amendt, P.; Bennett, D.; Chen, H.; Dewald, E.; Goyon, C.; Graziani, F.; Johnson, S.; Khan, S.; Landen, O.; Nikroo, A.; Pino, J.; Ralph, J.; Seugling, R.; Strozzi, D.; Tipton, R.; Tommasini, R.; Wang, M.; Loomis, E.; Merritt, E.; Montgomery, D.

    2017-10-01

    A new design of the double-shell approach predicts a high coupling efficiency from the hohlraum to the capsule, with 700 kJ in the capsule instead of 200kJ in the conventional low-Z single-shell scheme, improving prospects of double-shell performance. A recent experiment on NIF has evaluated a first step toward this goal of energy coupling using 0.7x subscale Al capsule, Au rugby hohlraum and 1MJ drive. A shell velocity of 150 μm/ns was measured, DANTE peak temperature of 255 eV was measured, and shell kinetic energy of 36 kJ was inferred using a rocket model, all close to predictions and consistent with 330kJ of total energy coupled to the capsule. Data analysis and more results from subsequent experiments will be presented. In the next step, an additional 2x increase of total coupled energy up to 700 kJ is projected for full-scale 2-MJ drive in U Rugby hohlraum. This work was performed under DOE contract DE-AC52-07NA27344.

  2. Improved method to demonstrate the structural integrity of high density fuel storage racks

    International Nuclear Information System (INIS)

    Hinderks, M.; Ungoreit, H.; Kremer, G.

    2001-01-01

    Reracking of existing fuel pools to the maximum extent is desirable from an economical point of view. This goal can be achieved by minimizing the gaps between the spent fuel storage racks. Since the rack design is aimed at enabling consolidated fuel rod storage, additional requirements arise with respect to the design and the structural analysis. The loads resulting from seismic events are decisive for the structural analysis and require a specially detailed and in-depth analysis for high seismic loads. The verification of structural integrity and functionality is performed in two phases. In the first phase the motional behavior of single racks, rows of racks and, where required, of all racks in the pool is simulated by excitation with displacement time histories under consideration of the fluid-structure interaction (FSI). The displacements from these simulations are evaluated, while the loads are utilized as input data for the structural analysis of the racks and the pool floor. The structural analyses for the racks comprise substantially stress analyses for base material and welds as well as stability analyses for the support channels and the rack outside walls. The analyses are performed in accordance with the specified codes and standards

  3. A methodological approach to studying resilience mechanisms: demonstration of utility in age and Alzheimer's disease-related brain pathology.

    Science.gov (United States)

    Wolf, Dominik; Fischer, Florian Udo; Fellgiebel, Andreas

    2018-05-01

    The present work aims at providing a methodological approach for the investigation of resilience factors and mechanisms in normal aging, Alzheimer's disease (AD) and other neurodegenerative disorders. By expanding and re-conceptualizing traditional regression approaches, we propose an approach that not only aims at identifying potential resilience factors but also allows for a differentiation between general and dynamic resilience factors in terms of their association with pathology. Dynamic resilience factors are characterized by an increasing relevance with increasing levels of pathology, while the relevance of general resilience factors is independent of the amount of pathology. Utility of the approach is demonstrated in age and AD-related brain pathology by investigating widely accepted resilience factors, including education and brain volume. Moreover, the approach is used to test hippocampal volume as potential resilience factor. Education and brain volume could be identified as general resilience factors against age and AD-related pathology. Beyond that, analyses highlighted that hippocampal volume may not only be disease target but also serve as a potential resilience factor in age and AD-related pathology, particularly at higher levels of tau-pathology (i.e. dynamic resilience factor). Given its unspecific and superordinate nature the approach is suitable for the investigation of a wide range of potential resilience factors in normal aging, AD and other neurodegenerative disorders. Consequently, it may find a wide application and thereby promote the comparability between studies.

  4. Systems-level computational modeling demonstrates fuel selection switching in high capacity running and low capacity running rats

    Science.gov (United States)

    Qi, Nathan R.

    2018-01-01

    High capacity and low capacity running rats, HCR and LCR respectively, have been bred to represent two extremes of running endurance and have recently demonstrated disparities in fuel usage during transient aerobic exercise. HCR rats can maintain fatty acid (FA) utilization throughout the course of transient aerobic exercise whereas LCR rats rely predominantly on glucose utilization. We hypothesized that the difference between HCR and LCR fuel utilization could be explained by a difference in mitochondrial density. To test this hypothesis and to investigate mechanisms of fuel selection, we used a constraint-based kinetic analysis of whole-body metabolism to analyze transient exercise data from these rats. Our model analysis used a thermodynamically constrained kinetic framework that accounts for glycolysis, the TCA cycle, and mitochondrial FA transport and oxidation. The model can effectively match the observed relative rates of oxidation of glucose versus FA, as a function of ATP demand. In searching for the minimal differences required to explain metabolic function in HCR versus LCR rats, it was determined that the whole-body metabolic phenotype of LCR, compared to the HCR, could be explained by a ~50% reduction in total mitochondrial activity with an additional 5-fold reduction in mitochondrial FA transport activity. Finally, we postulate that over sustained periods of exercise that LCR can partly overcome the initial deficit in FA catabolic activity by upregulating FA transport and/or oxidation processes. PMID:29474500

  5. Overview of ERA Integrated Technology Demonstration (ITD) 51A Ultra-High Bypass (UHB) Integration for Hybrid Wing Body (HWB)

    Science.gov (United States)

    Flamm, Jeffrey D.; James, Kevin D.; Bonet, John T.

    2016-01-01

    The NASA Environmentally Responsible Aircraft Project (ERA) was a ve year project broken into two phases. In phase II, high N+2 Technical Readiness Level demonstrations were grouped into Integrated Technology Demonstrations (ITD). This paper describes the work done on ITD-51A: the Vehicle Systems Integration, Engine Airframe Integration Demonstration. Refinement of a Hybrid Wing Body (HWB) aircraft from the possible candidates developed in ERA Phase I was continued. Scaled powered, and unpowered wind- tunnel testing, with and without acoustics, in the NASA LARC 14- by 22-foot Subsonic Tunnel, the NASA ARC Unitary Plan Wind Tunnel, and the 40- by 80-foot test section of the National Full-Scale Aerodynamics Complex (NFAC) in conjunction with very closely coupled Computational Fluid Dynamics was used to demonstrate the fuel burn and acoustic milestone targets of the ERA Project.

  6. Small-scale demonstration of high-level radioactive waste processing and solidification using actual SRP waste

    International Nuclear Information System (INIS)

    Okeson, J.K.; Galloway, R.M.; Wilhite, E.L.; Woolsey, G.B.; Ferguson, R.B.

    1980-01-01

    A small-scale demonstration of the high-level radioactive waste solidification process by vitrification in borosilicate glass is being conducted using 5-6 liter batches of actual waste. Equipment performance and processing characteristics of the various unit operations in the process are reported and, where appropriate, are compared to large-scale results obtained with synthetic waste

  7. Small-scale integrated demonstration of high-level radioactive waste processing and vitrification using actual SRP waste

    International Nuclear Information System (INIS)

    Ferguson, R.B.; Woolsey, G.B.; Galloway, R.M.; Baumgarten, P.M.; Eibling, R.E.

    1980-01-01

    Experiments have been made to demonstrate the feasibility of immobilizing SRP high-level waste in borosilicate glass. Results to date are encouraging. Equipment performance and processing characteristics for solidifying small batches of actual SRP waste have agreed well with previous experience with small- and large-scale tests synthetic waste, and with theoretical predictions

  8. High blood pressure - medicine-related

    Science.gov (United States)

    Drug-induced hypertension is high blood pressure caused by using a chemical substance or medicine. ... of the arteries There are several types of high blood pressure : Essential hypertension has no cause that can be ...

  9. High resolution diffraction imaging of mercuric iodide: Demonstration of the necessity for alternate crystal processing techniques for highly purified material

    International Nuclear Information System (INIS)

    Steiner, B.; Berg, L. van den; Laor, U.

    1995-01-01

    The overall crystalline lattice uniformity in recently available, highly purified mercuric iodide single crystals has been shown to be impacted by crystal handling techniques that were previously satisfactory. High resolution diffraction imaging of the surface regularity of crystals of various levels of purity and growth orientation shows: (1) that the newer materials have a generally lower level of precipitates, (2) that the incidence of these precipitates is now closely correlated with growth direction, and (3) that the deformation resistance and resulting sensitivity to crystal handling procedures are also closely correlated with these factors in this soft material. As a result, gentler cutting and polishing procedures have been developed and are shown to be effective in preserving overall lattice regularity in the new material. The polishing required to remove residual surface scratches affect the lattice orientation of the softer, precipitate-free regions, while not affecting those regions with detectable levels of precipitates. These results correlate closely with the electrical properties of devices made from these crystals. Mercuric iodide single crystals have proved to be particularly useful for x and γ ray detectors because their room temperature operation allow for simple, efficient, and compact instrumentation

  10. Observing Exoplanets with High-dispersion Coronagraphy. II. Demonstration of an Active Single-mode Fiber Injection Unit

    Energy Technology Data Exchange (ETDEWEB)

    Mawet, D.; Ruane, G.; Xuan, W.; Echeverri, D.; Klimovich, N.; Randolph, M.; Fucik, J.; Wang, J.; Dekany, R.; Delorme, J.-R. [Department of Astronomy, California Institute of Technology, 1200 East California Boulevard, MC 249-17, Pasadena, CA 91125 (United States); Wallace, J. K.; Vasisht, G.; Mennesson, B.; Choquet, E.; Serabyn, E., E-mail: dmawet@astro.caltech.edu [Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Drive, Pasadena, CA 91109 (United States)

    2017-04-01

    High-dispersion coronagraphy (HDC) optimally combines high-contrast imaging techniques such as adaptive optics/wavefront control plus coronagraphy to high spectral resolution spectroscopy. HDC is a critical pathway toward fully characterizing exoplanet atmospheres across a broad range of masses from giant gaseous planets down to Earth-like planets. In addition to determining the molecular composition of exoplanet atmospheres, HDC also enables Doppler mapping of atmosphere inhomogeneities (temperature, clouds, wind), as well as precise measurements of exoplanet rotational velocities. Here, we demonstrate an innovative concept for injecting the directly imaged planet light into a single-mode fiber, linking a high-contrast adaptively corrected coronagraph to a high-resolution spectrograph (diffraction-limited or not). Our laboratory demonstration includes three key milestones: close-to-theoretical injection efficiency, accurate pointing and tracking, and on-fiber coherent modulation and speckle nulling of spurious starlight signal coupling into the fiber. Using the extreme modal selectivity of single-mode fibers, we also demonstrated speckle suppression gains that outperform conventional image-based speckle nulling by at least two orders of magnitude.

  11. Immunohistochemical expression of EGFR in colorectal carcinoma correlates with high but not low level gene amplification, as demonstrated by CISH.

    Science.gov (United States)

    Hemmings, Chris; Broomfield, Amy; Bean, Elaine; Whitehead, Martin; Yip, Desmond

    2009-01-01

    To assess and compare immunohistochemical expression of epidermal growth factor receptor (EGFR) with gene amplification as demonstrated by chromogenic in situ hybridisation (CISH), in colorectal adenocarcinoma. Sections from 100 consecutive colorectal cancer resection specimens were stained for EGFR using immunohistochemistry and CISH. Immunohistochemical assessment was independently performed at two laboratories, using the same antibody and protocols. With immunohistochemistry, strong circumferential membrane staining (3+ staining) was demonstrated in only 5% of cases, and this was only focal in three of five cases. At one laboratory, weak or incomplete staining (1+ or 2+) was observed in five further cases (5%), which had been negative at the other laboratory. CISH demonstrated high level gene amplification (>10 copies/nucleus) in the same five cases which had demonstrated 3+ staining with immunohistochemistry, and in those cases where the staining was focal, the amplification was demonstrated in the same foci of the tumour. Five further cases (5%) had low level amplification (5-10 copies per nucleus); these cases did not exhibit significant positive staining with immunohistochemistry. All the cases which demonstrated gene amplification (high or low level) arose in the distal colon. There was no correlation between gene amplification status and a variety of other variables, including stage at diagnosis, mucinous differentiation, neuroendocrine differentiation, or loss of expression of mismatch repair proteins. Immunohistochemical expression of EGFR is variable between laboratories, even using standardised protocols. 3+ staining is predictive of high level gene amplification, but correlates very poorly with low level amplification, which may still be clinically significant. In some cases gene amplification was only focal, offering a potential explanation for poor response to targeted therapy in patients with EGFR positive tumours.

  12. Experimental demonstration of OpenFlow-enabled media ecosystem architecture for high-end applications over metro and core networks.

    Science.gov (United States)

    Ntofon, Okung-Dike; Channegowda, Mayur P; Efstathiou, Nikolaos; Rashidi Fard, Mehdi; Nejabati, Reza; Hunter, David K; Simeonidou, Dimitra

    2013-02-25

    In this paper, a novel Software-Defined Networking (SDN) architecture is proposed for high-end Ultra High Definition (UHD) media applications. UHD media applications require huge amounts of bandwidth that can only be met with high-capacity optical networks. In addition, there are requirements for control frameworks capable of delivering effective application performance with efficient network utilization. A novel SDN-based Controller that tightly integrates application-awareness with network control and management is proposed for such applications. An OpenFlow-enabled test-bed demonstrator is reported with performance evaluations of advanced online and offline media- and network-aware schedulers.

  13. People at High Risk of Developing Flu-Related Complications

    Science.gov (United States)

    ... Influenza Types Seasonal Avian Swine Variant Pandemic Other People at High Risk of Developing Flu–Related Complications ... related complications if they get sick with influenza. People at High Risk for Developing Flu-Related Complications ...

  14. Demonstration of Enhanced Radiation Drive in Hohlraums Made from a Mixture of High-Z Wall Materials

    International Nuclear Information System (INIS)

    Schein, Jochen; Jones, Ogden; Rosen, Mordecai; Dewald, Eduard; Glenzer, Siegfried; Gunther, Janelle; Hammel, Bruce; Landen, Otto; Suter, Laurence; Wallace, Russell

    2007-01-01

    We present results from experiments, numerical simulations and analytic modeling, demonstrating enhanced hohlraum performance. Care in the fabrication and handling of hohlraums with walls consisting of high-Z mixtures (cocktails) has led to our demonstration, for the first time, of a significant increase in radiation temperature compared to a pure Au hohlraum that is in agreement with predictions and is ascribable to reduced wall losses. The data suggest that a National Ignition Facility ignition hohlraum made of a U:Au:Dy cocktail should have ∼17% reduction in wall losses compared to a similar gold hohlraum

  15. Disposal demonstration of a high integrity container (HIC) containing an EPICOR-II prefilter from Three Mile Island

    International Nuclear Information System (INIS)

    McConnell, J.W. Jr.; Tyacke, M.J.; Schmitt, R.C.; Reno, H.W.

    1985-02-01

    A high integrity container (HIC) was developed, tested, and certified for use in disposing of unusual low-level radioactive waste from Three Mile Island Unit 2 (TMI-2). The work was coordinated by EG and G Idaho, Inc. and funded by the US Department of Energy. A disposal demonstration using an HIC containing an EPICOR-II prefilter from TMI-2 was completed at the commercial disposal facility in the State of Washington. A Certification of Compliance was issued by the Department of Social and Health Services of the State of Washington to use the HIC in disposing of up to 50 EPICOR-II prefilters. That Certification of Compliance was issued after rigorous review of the HIC design and test program by the State and by the US Nuclear Regulatory Commission. This report describes the processes of loading, transporting, and disposing of the demonstration HIC and briefly describes the design, testing, and approval effort leading up to the demonstration

  16. DYNAMISM OF DOT SUBRETINAL DRUSENOID DEPOSITS IN AGE-RELATED MACULAR DEGENERATION DEMONSTRATED WITH ADAPTIVE OPTICS IMAGING.

    Science.gov (United States)

    Zhang, Yuhua; Wang, Xiaolin; Godara, Pooja; Zhang, Tianjiao; Clark, Mark E; Witherspoon, C Douglas; Spaide, Richard F; Owsley, Cynthia; Curcio, Christine A

    2018-01-01

    To investigate the natural history of dot subretinal drusenoid deposits (SDD) in age-related macular degeneration, using high-resolution adaptive optics scanning laser ophthalmoscopy. Six eyes of four patients with intermediate age-related macular degeneration were studied at baseline and 1 year later. Individual dot SDD within the central 30° retina were examined with adaptive optics scanning laser ophthalmoscopy and optical coherence tomography. A total of 269 solitary SDD were identified at baseline. Over 12.25 ± 1.18 months, all 35 Stage 1 SDD progressed to advanced stages. Eighteen (60%) Stage 2 lesions progressed to Stage 3 and 12 (40%) remained at Stage 2. Of 204 Stage 3 SDD, 12 (6.4%) disappeared and the rest remained. Twelve new SDD were identified, including 6 (50%) at Stage 1, 2 (16.7%) at Stage 2, and 4 (33.3%) at Stage 3. The mean percentage of the retina affected by dot SDD, measured by the adaptive optics scanning laser ophthalmoscopy, increased in 5/6 eyes (from 2.31% to 5.08% in the most changed eye) and decreased slightly in 1/6 eye (from 10.67% to 10.54%). Dynamism, the absolute value of the areas affected by new and regressed lesions, ranged from 0.7% to 9.3%. Adaptive optics scanning laser ophthalmoscopy reveals that dot SDD, like drusen, are dynamic.

  17. Suitability of second pass RO as a substitute for high quality MSF product water in Nuclear Desalination Demonstration Plant

    International Nuclear Information System (INIS)

    Murugan, V.; Venkatesh, P.; Balasubramanian, C.; Nagaraj, R.; Yadav, Manoj Kumar; Prabhakar, S.; Tewari, P.K.

    2012-01-01

    Nuclear Desalination Demonstration Plant at Kalpakkam consists of both Multi Stage Flash Distillation (MSF) and Seawater Reverse Osmosis (SWRO) process to produce desalinated water. It supplies part of highly pure water from MSF to Madras Atomic Power Station for its boiler feed requirements and remaining water is blend with SWRO product water and sent to other common facilities located inside Kalpakkam campus. A critical techno-economic analysis is carried out to find out the suitability of second pass RO to sustain the availability of highly pure water in case of MSF plant shutdown. (author)

  18. Experimental programmes related to high burnup fuel

    International Nuclear Information System (INIS)

    Vasudeva Rao, P.R.; Vidhya, R.; Ananthasivan, K.; Srinivasan, T.G.; Nagarajan, K.

    2002-01-01

    The experimental programmes undertaken at IGCAR with regard to high burn-up fuels fall under the following categories: a) studies on fuel behaviour, b) development of extractants for aqueous reprocessing and c) development of non-aqueous reprocessing techniques. An experimental programme to measure the carbon potential in U/Pu-FP-C systems by methane-hydrogen gas equilibration technique has been initiated at IGCAR in order to understand the evolution of fuel and fission product phases in carbide fuel at high burn-up. The carbon potentials in U-Mo-C system have been measured by this technique. The free energies and enthalpies of formation of LaC 2 , NdC 2 and SmC 2 have been measured by measuring the vapor pressures of CO over the region Ln 2 O 3 -LnC 2 -C during the carbothermic reduction of Ln 2 O 3 by C. The decontamination from fission products achieved in fuel reprocessing depends strongly on the actinide loading of the extractant phase. Tri-n-butyl phosphate (TBP), presently used as the extractant, does not allow high loadings due to its propensity for third phase formation in the extraction of Pu(IV). A detailed study of the allowable Pu loadings in TBP and other extractants has been undertaken in IGCAR, the results of which are presented in this paper. The paper also describes the status of our programme to develop a non-aqueous route for the reprocessing of fast reactor fuels. (author)

  19. Use of Neuropsychological Tests to Identify High School Students with Epilepsy Who Later Demonstrate Inadequate Performances in Life.

    Science.gov (United States)

    Dodrill, Carl B.; Clemmons, David

    1984-01-01

    Examined the validity of intellectual, neuropsychological, and emotional adjustment measures administered in high school in predicting vocational adjustment of 39 young adults with epilepsy. Results showed neuropsychological tests were the best predictors of later adjustment. Abilities were more related to final adjustment than variables…

  20. Demonstration of a 100-kWth high-temperature solar thermochemical reactor pilot plant for ZnO dissociation

    Science.gov (United States)

    Koepf, E.; Villasmil, W.; Meier, A.

    2016-05-01

    Solar thermochemical H2O and CO2 splitting is a viable pathway towards sustainable and large-scale production of synthetic fuels. A reactor pilot plant for the solar-driven thermal dissociation of ZnO into metallic Zn has been successfully developed at the Paul Scherrer Institute (PSI). Promising experimental results from the 100-kWth ZnO pilot plant were obtained in 2014 during two prolonged experimental campaigns in a high flux solar simulator at PSI and a 1-MW solar furnace in Odeillo, France. Between March and June the pilot plant was mounted in the solar simulator and in-situ flow-visualization experiments were conducted in order to prevent particle-laden fluid flows near the window from attenuating transparency by blocking incoming radiation. Window flow patterns were successfully characterized, and it was demonstrated that particle transport could be controlled and suppressed completely. These results enabled the successful operation of the reactor between August and October when on-sun experiments were conducted in the solar furnace in order to demonstrate the pilot plant technology and characterize its performance. The reactor was operated for over 97 hours at temperatures as high as 2064 K; over 28 kg of ZnO was dissociated at reaction rates as high as 28 g/min.

  1. Demonstration of radiation pulse shaping with nested-tungsten-wire-array pinches for high-yield inertial confinement fusion.

    Science.gov (United States)

    Cuneo, M E; Vesey, R A; Sinars, D B; Chittenden, J P; Waisman, E M; Lemke, R W; Lebedev, S V; Bliss, D E; Stygar, W A; Porter, J L; Schroen, D G; Mazarakis, M G; Chandler, G A; Mehlhorn, T A

    2005-10-28

    Nested wire-array pinches are shown to generate soft x-ray radiation pulse shapes required for three-shock isentropic compression and hot-spot ignition of high-yield inertial confinement fusion capsules. We demonstrate a reproducible and tunable foot pulse (first shock) produced by interaction of the outer and inner arrays. A first-step pulse (second shock) is produced by inner array collision with a central CH2 foam target. Stagnation of the inner array at the axis produces the third shock. Capsules optimized for several of these shapes produce 290-900 MJ fusion yields in 1D simulations.

  2. Demonstrating Multi-bit Magnetic Memory in the Fe8 High Spin Molecule by Muon Spin Rotation

    OpenAIRE

    Shafir, Oren; Keren, Amit; Maegawa, Satoru; Ueda, Miki; Amato, Alex; Baines, Chris

    2005-01-01

    We developed a method to detect the quantum nature of high spin molecules using muon spin rotation, and a three-step field cycle ending always with the same field. We use this method to demonstrate that the Fe8 molecule can remember 6 (possibly 8) different histories (bits). A wide range of fields can be used to write a particular bit, and the information is stored in discrete states. Therefore, Fe8 can be used as a model compound for Multi-bit Magnetic Memory. Our experiment also paves the w...

  3. Demonstration of a diode-laser-based high spectral resolution lidar (HSRL) for quantitative profiling of clouds and aerosols.

    Science.gov (United States)

    Hayman, Matthew; Spuler, Scott

    2017-11-27

    We present a demonstration of a diode-laser-based high spectral resolution lidar. It is capable of performing calibrated retrievals of aerosol and cloud optical properties at a 150 m range resolution with less than 1 minute integration time over an approximate range of 12 km during day and night. This instrument operates at 780 nm, a wavelength that is well established for reliable semiconductor lasers and detectors, and was chosen because it corresponds to the D2 rubidium absorption line. A heated vapor reference cell of isotopic rubidium 87 is used as an effective and reliable aerosol signal blocking filter in the instrument. In principle, the diode-laser-based high spectral resolution lidar can be made cost competitive with elastic backscatter lidar systems, yet delivers a significant improvement in data quality through direct retrieval of quantitative optical properties of clouds and aerosols.

  4. Smart grid demonstrators and experiments in France: Economic assessments of smart grids. Challenges, methods, progress status and demonstrators; Contribution of 'smart grid' demonstrators to electricity transport and market architectures; Challenges and contributions of smart grid demonstrators to the distribution network. Focus on the integration of decentralised production; Challenges and contributions of smart grid demonstrators to the evolution of providing-related professions and to consumption practices

    International Nuclear Information System (INIS)

    Sudret, Thierry; Belhomme, Regine; Nekrassov, Andrei; Chartres, Sophie; Chiappini, Florent; Drouineau, Mathilde; Hadjsaid, Nouredine; Leonard, Cedric; Bena, Michel; Buhagiar, Thierry; Lemaitre, Christian; Janssen, Tanguy; Guedou, Benjamin; Viana, Maria Sebastian; Malarange, Gilles; Hadjsaid, Nouredine; Petit, Marc; Lehec, Guillaume; Jahn, Rafael; Gehain, Etienne

    2015-01-01

    This publication proposes a set of four articles which give an overview of challenges and contributions of smart grid demonstrators for the French electricity system according to different perspectives and different stakeholders. These articles present the first lessons learned from these demonstrators in terms of technical and technological innovations, of business and regulation models, and of customer behaviour and acceptance. More precisely, the authors discuss economic assessments of smart grids with an overview of challenges, methods, progress status and existing smart grid programs in the World, comment the importance of the introduction of intelligence at hardware, software and market level, highlight the challenges and contributions of smart grids for the integration of decentralised production, and discuss how smart grid demonstrators impact providing-related professions and customer consumption practices

  5. Initial demonstration of the NRC`s capability to conduct a performance assessment for a High-Level Waste Repository

    Energy Technology Data Exchange (ETDEWEB)

    Codell, R.; Eisenberg, N.; Fehringer, D.; Ford, W.; Margulies, T.; McCartin, T.; Park, J.; Randall, J.

    1992-05-01

    In order to better review licensing submittals for a High-Level Waste Repository, the US Nuclear Regulatory Commission staff has expanded and improved its capability to conduct performance assessments. This report documents an initial demonstration of this capability. The demonstration made use of the limited data from Yucca Mountain, Nevada to investigate a small set of scenario classes. Models of release and transport of radionuclides from a repository via the groundwater and direct release pathways provided preliminary estimates of releases to the accessible environment for a 10,000 year simulation time. Latin hypercube sampling of input parameters was used to express results as distributions and to investigate model sensitivities. This methodology demonstration should not be interpreted as an estimate of performance of the proposed repository at Yucca Mountain, Nevada. By expanding and developing the NRC staff capability to conduct such analyses, NRC would be better able to conduct an independent technical review of the US Department of Energy (DOE) licensing submittals for a high-level waste (HLW) repository. These activities were divided initially into Phase 1 and Phase 2 activities. Additional phases may follow as part of a program of iterative performance assessment at the NRC. The NRC staff conducted Phase 1 activities primarily in CY 1989 with minimal participation from NRC contractors. The Phase 2 activities were to involve NRC contractors actively and to provide for the transfer of technology. The Phase 2 activities are scheduled to start in CY 1990, to allow Sandia National Laboratories to complete development and transfer of computer codes and the Center for Nuclear Waste Regulatory Analyses (CNWRA) to be in a position to assist in the acquisition of the codes.

  6. Proof-of-principle demonstration of Nb3Sn superconducting radiofrequency cavities for high Q0 applications

    Science.gov (United States)

    Posen, S.; Liepe, M.; Hall, D. L.

    2015-02-01

    Many future particle accelerators require hundreds of superconducting radiofrequency (SRF) cavities operating with high duty factor. The large dynamic heat load of the cavities causes the cryogenic plant to make up a significant part of the overall cost of the facility. This contribution can be reduced by replacing standard niobium cavities with ones coated with a low-dissipation superconductor such as Nb3Sn. In this paper, we present results for single cell cavities coated with Nb3Sn at Cornell. Five coatings were carried out, showing that at 4.2 K, high Q0 out to medium fields was reproducible, resulting in an average quench field of 14 MV/m and an average 4.2 K Q0 at quench of 8 × 109. In each case, the peak surface magnetic field at quench was well above Hc1, showing that it is not a limiting field in these cavities. The coating with the best performance had a quench field of 17 MV/m, exceeding gradient requirements for state-of-the-art high duty factor SRF accelerators. It is also shown that—taking into account the thermodynamic efficiency of the cryogenic plant—the 4.2 K Q0 values obtained meet the AC power consumption requirements of state-of-the-art high duty factor accelerators, making this a proof-of-principle demonstration for Nb3Sn cavities in future applications.

  7. High-fidelity hybrid simulation of allergic emergencies demonstrates improved preparedness for office emergencies in pediatric allergy clinics.

    Science.gov (United States)

    Kennedy, Joshua L; Jones, Stacie M; Porter, Nicholas; White, Marjorie L; Gephardt, Grace; Hill, Travis; Cantrell, Mary; Nick, Todd G; Melguizo, Maria; Smith, Chris; Boateng, Beatrice A; Perry, Tamara T; Scurlock, Amy M; Thompson, Tonya M

    2013-01-01

    Simulation models that used high-fidelity mannequins have shown promise in medical education, particularly for cases in which the event is uncommon. Allergy physicians encounter emergencies in their offices, and these can be the source of much trepidation. To determine if case-based simulations with high-fidelity mannequins are effective in teaching and retention of emergency management team skills. Allergy clinics were invited to Arkansas Children's Hospital Pediatric Understanding and Learning through Simulation Education center for a 1-day workshop to evaluate skills concerning the management of allergic emergencies. A Clinical Emergency Preparedness Team Performance Evaluation was developed to evaluate the competence of teams in several areas: leadership and/or role clarity, closed-loop communication, team support, situational awareness, and scenario-specific skills. Four cases, which focus on common allergic emergencies, were simulated by using high-fidelity mannequins and standardized patients. Teams were evaluated by multiple reviewers by using video recording and standardized scoring. Ten to 12 months after initial training, an unannounced in situ case was performed to determine retention of the skills training. Clinics showed significant improvements for role clarity, teamwork, situational awareness, and scenario-specific skills during the 1-day workshop (all P clinics (all P ≤ .004). Clinical Emergency Preparedness Team Performance Evaluation scores demonstrated improved team management skills with simulation training in office emergencies. Significant recall of team emergency management skills was demonstrated months after the initial training. Copyright © 2013 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

  8. Exploiting graph kernels for high performance biomedical relation extraction.

    Science.gov (United States)

    Panyam, Nagesh C; Verspoor, Karin; Cohn, Trevor; Ramamohanarao, Kotagiri

    2018-01-30

    performed better than APG kernel for the BioInfer dataset, in the Area Under Curve (AUC) measure (74% vs 69%). However, for all the other PPI datasets, namely AIMed, HPRD50, IEPA and LLL, ASM is substantially outperformed by the APG kernel in F-score and AUC measures. We demonstrate a high performance Chemical Induced Disease relation extraction, without employing external knowledge sources or task specific heuristics. Our work shows that graph kernels are effective in extracting relations that are expressed in multiple sentences. We also show that the graph kernels, namely the ASM and APG kernels, substantially outperform the tree kernels. Among the graph kernels, we showed the ASM kernel as effective for biomedical relation extraction, with comparable performance to the APG kernel for datasets such as the CID-sentence level relation extraction and BioInfer in PPI. Overall, the APG kernel is shown to be significantly more accurate than the ASM kernel, achieving better performance on most datasets.

  9. Demonstrating Enabling Technologies for the High-Resolution Imaging Spectrometer of the Next NASA X-ray Astronomy Mission

    Science.gov (United States)

    Kilbourne, Caroline; Adams, J. S.; Bandler, S.; Chervenak, J.; Chiao, M.; Doriese, R.; Eckart, M.; Finkbeiner, F.; Fowler, J. W.; Hilton, G.; Irwin, K.; Kelley, R. L.; Moseley, S. J.; Porter, F. S.; Reintsema, C.; Sadleir, J.; Smith, S. J.; Swetz, D.; Ullom, J.

    2014-01-01

    NASA/GSFC and NIST-Boulder are collaborating on a program to advance superconducting transition-edge sensor (TES) microcalorimeter technology toward Technology Readiness Level (TRL) 6. The technology development for a TES imaging X-ray microcalorimeter spectrometer (TES microcalorimeter arrays and time-division multiplexed SQUID readout) is now at TRL 4, as evaluated by both NASA and the European Space Agency (ESA) during mission formulation for the International X-ray Observatory (IXO). We will present the status of the development program. The primary goal of the current project is to advance the core X-ray Microcalorimeter Spectrometer (XMS) detector-system technologies to a demonstration of TRL 5 in 2014. Additional objectives are to develop and demonstrate two important related technologies to at least TRL 4: position-sensitive TES devices and code-division multiplexing (CDM). These technologies have the potential to expand significantly the range of possible instrument optimizations; together they allow an expanded focal plane and higher per-pixel count rates without greatly increasing mission resources. The project also includes development of a design concept and critical technologies needed for the thermal, electrical, and mechanical integration of the detector and readout components into the focal-plane assembly. A verified design concept for the packaging of the focal-plane components will be needed for the detector system eventually to advance to TRL 6. Thus, the current project is a targeted development and demonstration program designed to make significant progress in advancing the XMS detector system toward TRL 6, establishing its readiness for a range of possible mission implementations.

  10. Investigation and Demonstration of High Speed Full-Optical Hybrid FSO/Fiber Communication System under Light Sand Storm Condition

    KAUST Repository

    Esmail, Maged Abdullah; Ragheb, Amr; Fathallah, Habib; Alouini, Mohamed-Slim

    2016-01-01

    In contrast to traditional free space optical (FSO) systems, the new generation is aimed to be transparent to optical fiber where protocols, high signal bandwidths, and high data rates over fiber are all maintained. In this paper, we experimentally demonstrate a high speed outdoor full-optical FSO communication system over 100 m link. We first describe the design of our transmitter, which consists of a comb generator and a flexible multiformat transmitter. Our measurements are performed in arid desert area under a light dust storm. In this environment, we use a 12 subcarrier comb generator, each of which is modulated by a quadrature-amplitude modulation (QAM) signal. We achieved a 1.08 Tbps error free data rate with 3.6 b/s/Hz spectral efficiency. We place long optical fiber rolls in the transmitter side and the receiver side to mimic real FSO deployments. Furthermore, we investigated the effect of receiver misalignment in outdoor conditions and the effect of background noise. We find that full-optical FSO system is sensitive to the misalignment effect. However, the background noise has negligible effect. Finally, we find that solar heating of the transceiver causes collimator deviation, which requires using a cooling unit or auto tracking system.

  11. Investigation and Demonstration of High Speed Full-Optical Hybrid FSO/Fiber Communication System under Light Sand Storm Condition

    KAUST Repository

    Esmail, Maged Abdullah

    2016-12-19

    In contrast to traditional free space optical (FSO) systems, the new generation is aimed to be transparent to optical fiber where protocols, high signal bandwidths, and high data rates over fiber are all maintained. In this paper, we experimentally demonstrate a high speed outdoor full-optical FSO communication system over 100 m link. We first describe the design of our transmitter, which consists of a comb generator and a flexible multiformat transmitter. Our measurements are performed in arid desert area under a light dust storm. In this environment, we use a 12 subcarrier comb generator, each of which is modulated by a quadrature-amplitude modulation (QAM) signal. We achieved a 1.08 Tbps error free data rate with 3.6 b/s/Hz spectral efficiency. We place long optical fiber rolls in the transmitter side and the receiver side to mimic real FSO deployments. Furthermore, we investigated the effect of receiver misalignment in outdoor conditions and the effect of background noise. We find that full-optical FSO system is sensitive to the misalignment effect. However, the background noise has negligible effect. Finally, we find that solar heating of the transceiver causes collimator deviation, which requires using a cooling unit or auto tracking system.

  12. Demonstration of a High-Order Mode Input Coupler for a 220-GHz Confocal Gyrotron Traveling Wave Tube

    Science.gov (United States)

    Guan, Xiaotong; Fu, Wenjie; Yan, Yang

    2018-02-01

    A design of high-order mode input coupler for 220-GHz confocal gyrotron travelling wave tube is proposed, simulated, and demonstrated by experimental tests. This input coupler is designed to excite confocal TE 06 mode from rectangle waveguide TE 10 mode over a broadband frequency range. Simulation results predict that the optimized conversion loss is about 2.72 dB with a mode purity excess of 99%. Considering of the gyrotron interaction theory, an effective bandwidth of 5 GHz is obtained, in which the beam-wave coupling efficiency is higher than half of maximum. The field pattern under low power demonstrates that TE 06 mode is successfully excited in confocal waveguide at 220 GHz. Cold test results from the vector network analyzer perform good agreements with simulation results. Both simulation and experimental results illustrate that the reflection at input port S11 is sensitive to the perpendicular separation of two mirrors. It provides an engineering possibility for estimating the assembly precision.

  13. Analysis of Corrosion Residues Collected from the Aluminum Basket Rails of the High-Burnup Demonstration Cask.

    Energy Technology Data Exchange (ETDEWEB)

    Bryan, Charles R. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-03-01

    On September, 2015, an inspection was performed on the TN-32B cask that will be used for the high-burnup demonstration project. During the survey, wooden cribbing that had been placed within the cask eleven years earlier to prevent shifting of the basket during transport was removed, revealing two areas of residue on the aluminum basket rails, where they had contacted the cribbing. The residue appeared to be a corrosion product, and concerns were raised that similar attack could exist at more difficult-to-inspect locations in the canister. Accordingly, when the canister was reopened, samples of the residue were collected for analysis. This report presents the results of that assessment, which determined that the corrosion was due to the presence of the cribbing. The corrosion was associated with fungal material, and fungal activity likely contributed to an aggressive chemical environment. Once the cask has been cleaned, there will be no risk of further corrosion.

  14. Demonstration on endurance of ion exchange membrane immersed in high-concentration tritiated water under the Broader Approach Activities

    Energy Technology Data Exchange (ETDEWEB)

    Iwai, Yasunori, E-mail: iwai.yasunori@jaea.go.jp; Sato, Katsumi; Kawamura, Yoshinori; Yamanishi, Toshihiko

    2013-10-15

    Highlights: • Endurance of Nafion ion exchange membrane immersed in 1.38 × 10{sup 12} Bq/kg of highly concentrated tritiated water was demonstrated. • Degradation of Nafion backbone structure by tritium beta was similar to that by gamma rays and electron beams at an equivalent dose. • Degradation directly by radiation was dominant at room temperature compared with that by reactions with radicals produced from water radiolysis. -- Abstract: The Nafion{sup ®} ion exchange membrane is a key material for electrolysis cells of the water detritiation system. Endurance of Nafion ion exchange membrane immersed in 1.38 × 10{sup 12} Bq/kg of highly concentrated tritiated water has been demonstrated at room temperature for up to 2 years under the Broader Approach Activities. The curves of percent elongation at break vs. dose and tensile strength vs. dose for the Nafion membranes immersed in tritiated water were well consistent with those for Nafion membranes irradiated to an equivalent dose with gamma rays and electron beams. This shows that the degradation of Nafion backbone structure by tritium beta is similar to that by gamma rays and electron beams. The results of ferric Fenton test indicated that the degradation directly by radiation was dominant at room temperature compared with that by reactions with radicals produced from water radiolysis. The curve of ion exchange capacity vs. dose for the Nafion membranes immersed in tritiated water was also well consistent with that for Nafion membranes irradiated to an equivalent dose with gamma rays and electron beams. These results showed irradiation tests with gamma rays and electron beams were alternative for predicting degradation of ion exchange membrane by tritium beta.

  15. Ecological sustainability and personal behavior: relations demonstrated by the decision-making process of selecting a certain transportation mean

    Energy Technology Data Exchange (ETDEWEB)

    Priewasser, Reinhold [Linz Univ., Inst. for Environmental Management in Enterprises and Regions, Linz (Austria)

    1999-07-01

    Facing the aim of ecological sustainability only little emphasis has been placed on the fact that the extent of environmental stresses is not only a consequence of certain factual or structural conditions but also essentially determined by varying human behaviour patterns. Technologies and structures are not ecologically effective by themselves, their environmental relevance strongly depends on the persons' way of acting within the prevailing system. Recognising the importance of that perspective psychological and social theories about the generation of personal behaviour as well as the theoretical models of learning can offer useful indications concerning the interpersonal and extrapersonal preconditions of environmentally oriented acting. With reference to the decision-making process of selecting a certain transportation mean, the influences of rational and emotional factors and obstacles to an ecologically sustainable personal act should be exemplary demonstrated. At the same time very effective points of departure for behavioural change can be identified. (Author)

  16. The appearances of oesophageal carcinoma demonstrated on high-resolution, T2-weighted MRI, with histopathological correlation

    International Nuclear Information System (INIS)

    Riddell, A.M.; Allum, W.H.; Thompson, J.N.; Wotherspoon, A.C.; Richardson, C.; Brown, G.

    2007-01-01

    This paper describes the spectrum of imaging features of oesophageal adenocarcinoma seen using high-resolution T2-weighted (T2W) magnetic resonance imaging (MRI). Thirty-nine patients with biopsy-proven oesophageal adenocarcinoma were scanned using an external surface coil. A sagittal T2W sequence was used to localise the tumour and to plan axial images perpendicular to the tumour. Fast spin-echo (FSE) T2W axial sequence parameters were: TR/TE, 3,300-5,000 ms/120-80 ms; field of view (FOV) 225 mm, matrix 176 x 512(reconstructed) mm to 256 x 224 mm, giving an in-plane resolution of between 1.28 x 0.44 mm and 0.88 x 1.00 mm, with 3-mm slice thickness. Thirty-three patients underwent resection and the MR images were compared with the histological whole-mount sections. There were four T1, 12 T2, and 17 T3 tumours. The T2W high-resolution MRI sequences produced detailed images of the oesophageal wall and surrounding structures. Analysis of the imaging appearances for different tumour T stages enabled the development of imaging criteria for local staging of oesophageal cancer using high-resolution MRI. Our study illustrates the spectrum of appearances of oesophageal cancer on T2W high-resolution MRI, and using the criteria established in this study, demonstrates the potential of this technique as an alternative non-invasive method for local staging for oesophageal cancer. (orig.)

  17. Optical interconnects for in-plane high-speed signal distribution at 10 Gb/s: Analysis and demonstration

    Science.gov (United States)

    Chang, Yin-Jung

    With decreasing transistor size, increasing chip speed, and larger numbers of processors in a system, the performance of a module/system is being limited by the off-chip and off-module bandwidth-distance products. Optical links have moved from fiber-based long distance communications to the cabinet level of 1m--100m, and recently to the backplane-level (10cm--1m). Board-level inter-chip parallel optical interconnects have been demonstrated recently by researchers from Intel, IBM, Fujitsu, NTT and a few research groups in universities. However, the board-level signal/clock distribution function using optical interconnects, the lightwave circuits, the system design, a practically convenient integration scheme committed to the implementation of a system prototype have not been explored or carefully investigated. In this dissertation, the development of a board-level 1 x 4 optical-to-electrical signal distribution at 10Gb/s is presented. In contrast to other prototypes demonstrating board-level parallel optical interconnects that have been drawing much attention for the past decade, the optical link design for the high-speed signal broadcasting is even more complicated and the pitch between receivers could be varying as opposed to fixed-pitch design that has been widely-used in the parallel optical interconnects. New challenges for the board-level high-speed signal broadcasting include, but are not limited to, a new optical link design, a lightwave circuit as a distribution network, and a novel integration scheme that can be a complete radical departure from the traditional assembly method. One of the key building blocks in the lightwave circuit is the distribution network in which a 1 x 4 multimode interference (MMI) splitter is employed. MMI devices operating at high data rates are important in board-level optical interconnects and need to be characterized in the application of board-level signal broadcasting. To determine the speed limitations of MMI devices, the

  18. Demonstration of electron clearing effect by means of a clearing electrode in high-intensity positron ring

    International Nuclear Information System (INIS)

    Suetsugu, Y.; Fukuma, H.; Wang, L.; Pivi, M.; Morishige, A.; Suzuki, Y.; Tsukamoto, M.; Tsuchiya, M.

    2009-01-01

    In the beam pipe of high-intensity positron/proton storage rings, undesired electron clouds may be first produced by photoelectrons and the ionization of residual gases; then the clouds increase by the secondary electron emission. In this study, a strip-line clearing electrode has been developed to mitigate the electron-cloud effect in high-intensity positron/proton storage rings. The electrode is composed of a thin tungsten layer with a thickness of 0.1 mm formed on a thin alumina ceramic layer with a thickness of 0.2 mm. The narrow alumina gap between the electrode and the beam pipe decreases the beam impedance and also enhances the heat transfer from the electrode to the beam pipe. A test model has been installed in the KEK B-factory (KEKB) positron ring, along with an electron monitor with a retarding grid. The electron density in a field free region decreased by one order of magnitude was observed on the application of ±500 V to the electrode at a beam current of 1.6 A with 1585 bunches. The reduction in the electron density was more drastic in a vertical magnetic field of 0.77 T, that is, the electron density decreased by several orders by applying +500 V to the electrode at the same beam current. This experiment is the first experiment demonstrating the principle of the clearing electrode that is used to mitigate the electron-cloud effect in a positron ring.

  19. Demonstration of High Performance in Layered Deuterium-Tritium Capsule Implosions in Uranium Hohlraums at the National Ignition Facility.

    Science.gov (United States)

    Döppner, T; Callahan, D A; Hurricane, O A; Hinkel, D E; Ma, T; Park, H-S; Berzak Hopkins, L F; Casey, D T; Celliers, P; Dewald, E L; Dittrich, T R; Haan, S W; Kritcher, A L; MacPhee, A; Le Pape, S; Pak, A; Patel, P K; Springer, P T; Salmonson, J D; Tommasini, R; Benedetti, L R; Bond, E; Bradley, D K; Caggiano, J; Church, J; Dixit, S; Edgell, D; Edwards, M J; Fittinghoff, D N; Frenje, J; Gatu Johnson, M; Grim, G; Hatarik, R; Havre, M; Herrmann, H; Izumi, N; Khan, S F; Kline, J L; Knauer, J; Kyrala, G A; Landen, O L; Merrill, F E; Moody, J; Moore, A S; Nikroo, A; Ralph, J E; Remington, B A; Robey, H F; Sayre, D; Schneider, M; Streckert, H; Town, R; Turnbull, D; Volegov, P L; Wan, A; Widmann, K; Wilde, C H; Yeamans, C

    2015-07-31

    We report on the first layered deuterium-tritium (DT) capsule implosions indirectly driven by a "high-foot" laser pulse that were fielded in depleted uranium hohlraums at the National Ignition Facility. Recently, high-foot implosions have demonstrated improved resistance to ablation-front Rayleigh-Taylor instability induced mixing of ablator material into the DT hot spot [Hurricane et al., Nature (London) 506, 343 (2014)]. Uranium hohlraums provide a higher albedo and thus an increased drive equivalent to an additional 25 TW laser power at the peak of the drive compared to standard gold hohlraums leading to higher implosion velocity. Additionally, we observe an improved hot-spot shape closer to round which indicates enhanced drive from the waist. In contrast to findings in the National Ignition Campaign, now all of our highest performing experiments have been done in uranium hohlraums and achieved total yields approaching 10^{16} neutrons where more than 50% of the yield was due to additional heating of alpha particles stopping in the DT fuel.

  20. Transmutation of high level nuclear waste in an accelerator driven system: towards a demonstration device of industrial interest (EUROTRANS)

    International Nuclear Information System (INIS)

    Knebel, Joachim U.; Ait Abderrahim, Hamid; Caron-Carles, Marylise

    2010-01-01

    The Integrated Project EUROTRANS (EURopean Research Programme for the TRANSmutation of High Level Nuclear Waste in an Accelerator Driven System) within the ongoing EURATOM 6th Framework Programme (FP6) is devoted to the study of transmutation of high-level waste from nuclear power plants. The work is focused on transmutation in an Accelerator Driven System (ADS). The objective of EUROTRANS is the assessment of the design and the feasibility of an industrial ADS prototype dedicated to transmutation. The necessary R and D results in the areas of accelerator components, fuel development, structural materials, thermal-hydraulics, heavy liquid metal technology and nuclear data will be made available, together with the experimental demonstration of the ADS component coupling. The outcome of this work will allow to provide a reasonably reliable assessment of technological feasibility and a cost estimate for ADS based transmutation, and to possibly decide on the detailed design of an experimental ADS and its construction in the future. EUROTRANS is integrating activities of 51 participants from 16 countries, within the industry (10 participants), the national research centres (20) and 17 universities. 16 universities are collectively represented by ENEN (European Nuclear Education Network). EUROTRANS is the continuation of the three FP5 Clusters FUETRA, BASTRA and TESTRA together with the PDS-XADS Project. It is a five-year project which started in April 2005

  1. High precision relative position sensing system for formation flying spacecraft

    Data.gov (United States)

    National Aeronautics and Space Administration — We propose to develop and test an optical sensing system that provides high precision relative position sensing for formation flying spacecraft.  A high precision...

  2. Do event-related potentials to infrequent decrements in duration of auditory stimuli demonstrate a memory trace in man?

    Science.gov (United States)

    Näätänen, R; Paavilainen, P; Reinikainen, K

    1989-12-15

    Sequences of identical acoustic stimuli were presented to normal subjects reading a book while event-related brain potentials (ERP) elicited by these stimuli were recorded. Occasional irrelevant decreases and increases in stimulus duration elicited an ERP component called the mismatch negativity (MMN). This component was larger over the right hemisphere irrespective of the ear stimulated. These data implicate memory representations which develop automatically and represent the physical features of the repetitive stimulus accurately. Further, when an input does not match with such a trace the MMN is generated. The memory traces involved appear to be those of the acoustic sensory memory, the 'echoic' memory.

  3. Postmortem computed tomographic (PMCT) demonstration of the relation between gastrointestinal (GI) distension and hepatic portal venous gas (HPVG)

    International Nuclear Information System (INIS)

    Shiotani, Seiji; Kohno, Mototsugu; Ohashi, Noriyoshi; Yamazaki, Kentaro; Nakayama, Hidetsugu; Watanabe, Ko

    2004-01-01

    The purpose of this study was to investigate the relation between gastrointestinal (GI) distension and hepatic portal venous gas (HPVG) on postmortem computed tomography (PMCT). Our subjects were 190 PMCT obtained within two hours of non-traumatic death [175 patients underwent cardiopulmonary resuscitation (CPR) and 15 patients did not undergo CPR]. We evaluated the incidence and location of GI distension (0=no distension, 1=stomach and duodenum, 2=more distal than 1) and HPVG (0=no gas, 1=left lobe, 2=1+right anterior lobe, 3=2+right posterior lobe). GI distension (grade 0/1/2=58/55/62 patients) and HPVG (grade 0/1/2/3=114/10/28/23 patients) were observed in 175 patients who underwent CPR. The grade of HPVG increased significantly in accordance with the advancement of GI distension. Fifteen patients without undergoing CPR showed no GI distension but one patient showed grade 1 HPVG. PMCT indicates the presence of a relation between GI distension and HPVG. (author)

  4. Observational demonstration of a high image rejection SIS mixer receiver using a new waveguide filter at 230 GHz

    Science.gov (United States)

    Hasegawa, Yutaka; Asayama, Shinichiro; Harada, Ryohei; Tokuda, Kazuki; Kimura, Kimihiro; Ogawa, Hideo; Onishi, Toshikazu

    2017-12-01

    A new sideband separation method was developed for use in millimeter-/submillimeter-band radio receivers using a novel waveguide frequency separation filter (FSF), which consists of two branch line hybrid couplers and two waveguide high-pass filters. The FSF was designed to allow the radio frequency (RF) signal to pass through to an output port when the frequency is higher than a certain value (225 GHz), and to reflect the RF signal back to another output port when the frequency is lower. The FSF is connected to two double sideband superconductor-insulator-superconductor (SIS) mixers, and an image rejection ratio (IRR) is determined by the FSF characteristics. With this new sideband separation method, we can achieve good and stable IRR without the balancing two SIS mixers such as is necessary for conventional sideband-separating SIS mixers. To demonstrate the applicability of this method, we designed and developed an FSF for simultaneous observations of the J = 2-1 rotational transition lines of three CO isotopes (12CO, 13CO, and C18O): the 12CO line is in the upper sideband and the others are in the lower sideband with an intermediate-frequency range of 4-8 GHz at the radio frequency of 220/230 GHz. This FSF was then installed in the receiver system of the 1.85 m radio telescope of Osaka Prefecture University, and was used during the 2014 observation season. The observation results indicate that the IRR of the proposed receiver is 25 dB or higher for the 12CO line, and no significant fluctuation larger than 1 dB in the IRR was observed throughout the season. These results demonstrate the practical utility of the FSF receiver for observations like extensive molecular cloud surveys in specified lines with a fixed frequency setting.

  5. Phylogenetic and functional analysis of metagenome sequence from high-temperature archaeal habitats demonstrate linkages between metabolic potential and geochemistry

    Directory of Open Access Journals (Sweden)

    William P. Inskeep

    2013-05-01

    Full Text Available Geothermal habitats in Yellowstone National Park (YNP provide an unparalled opportunity to understand the environmental factors that control the distribution of archaea in thermal habitats. Here we describe, analyze and synthesize metagenomic and geochemical data collected from seven high-temperature sites that contain microbial communities dominated by archaea relative to bacteria. The specific objectives of the study were to use metagenome sequencing to determine the structure and functional capacity of thermophilic archaeal-dominated microbial communities across a pH range from 2.5 to 6.4 and to discuss specific examples where the metabolic potential correlated with measured environmental parameters and geochemical processes occurring in situ. Random shotgun metagenome sequence (~40-45 Mbase Sanger sequencing per site was obtained from environmental DNA extracted from high-temperature sediments and/or microbial mats and subjected to numerous phylogenetic and functional analyses. Analysis of individual sequences (e.g., MEGAN and G+C content and assemblies from each habitat type revealed the presence of dominant archaeal populations in all environments, 10 of whose genomes were largely reconstructed from the sequence data. Analysis of protein family occurrence, particularly of those involved in energy conservation, electron transport and autotrophic metabolism, revealed significant differences in metabolic strategies across sites consistent with differences in major geochemical attributes (e.g., sulfide, oxygen, pH. These observations provide an ecological basis for understanding the distribution of indigenous archaeal lineages across high temperature systems of YNP.

  6. High-resolution dynamic angiography using flat-panel volume CT: feasibility demonstration for neuro and lower limb vascular applications

    International Nuclear Information System (INIS)

    Mehndiratta, Amit; Rabinov, James D.; Grasruck, Michael; Liao, Eric C.; Crandell, David; Gupta, Rajiv

    2015-01-01

    This paper evaluates a prototype flat-panel volume CT (fpVCT) for dynamic in vivo imaging in a variety of neurovascular and lower limb applications. Dynamic CTA was performed on 12 patients (neuro = 8, lower limb = 4) using an fpVCT with 120 kVp, 50 mA, rotation time varying from 8 to 19 s, and field of view of 25 x 25 x 18 cm 3 . Four-dimensional data sets (i.e. 3D images over time) were reconstructed and reviewed. Dynamic CTA demonstrated sufficient spatio-temporal resolution to elucidate first-pass and recirculation dynamics of contrast bolus through neurovasclar pathologies and phasic blood flow though lower-limb vasculature and grafts. The high spatial resolution of fpVCT resulted in reduced partial volume and metal beam-hardening artefacts. This facilitated assessment of vascular lumen in the presence of calcified plaque and evaluation of fractures, especially in the presence of fixation hardware. Evaluation of arteriovenous malformation using dynamic fpVCT angiography was of limited utility. Dynamic CTA using fpVCT can visualize time-varying phenomena in neuro and lower limb vascular applications and has sufficient diagnostic imaging quality to evaluate a number of pathologies affecting these regions. (orig.)

  7. Demonstration of Parallel Algal Processing: Production of Renewable Diesel Blendstock and a High-Value Chemical Intermediate

    Energy Technology Data Exchange (ETDEWEB)

    Knoshaug, Eric P [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Mohagheghi, Ali [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Nagle, Nicholas J [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Stickel, Jonathan J [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Dong, Tao [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Karp, Eric M [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Kruger, Jacob S [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Brandner, David [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Manker, Lorenz [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Rorrer, Nicholas [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Hyman, Deborah A [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Christensen, Earl D [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Pienkos, Philip T [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2017-12-19

    Co-production of high-value chemicals such as succinic acid from algal sugars is a promising route to enabling conversion of algal lipids to a renewable diesel blendstock. Biomass from the green alga Scenedesmus acutus was acid pretreated and the resulting slurry separated into its solid and liquor components using charged polyamide induced flocculation and vacuum filtration. Over the course of a subsequent 756 hours continuous fermentation of the algal liquor with Actinobacillus succinogenes 130Z, we achieved maximum productivity, process conversion yield, and titer of 1.1 g L-1 h-1, 0.7 g g-1 total sugars, and 30.5 g L-1 respectively. Succinic acid was recovered from fermentation media with a yield of 60% at 98.4% purity while lipids were recovered from the flocculated cake at 83% yield with subsequent conversion through deoxygenation and hydroisomerization to a renewable diesel blendstock. This work is a first-of-its-kind demonstration of a novel integrated conversion process for algal biomass to produce fuel and chemical products of sufficient quality to be blend-ready feedstocks for further processing.

  8. Demonstration of high-performance p-type tin oxide thin-film transistors using argon-plasma surface treatments

    Science.gov (United States)

    Bae, Sang-Dae; Kwon, Soo-Hun; Jeong, Hwan-Seok; Kwon, Hyuck-In

    2017-07-01

    In this work, we investigated the effects of low-temperature argon (Ar)-plasma surface treatments on the physical and chemical structures of p-type tin oxide thin-films and the electrical performance of p-type tin oxide thin-film transistors (TFTs). From the x-ray photoelectron spectroscopy measurement, we found that SnO was the dominant phase in the deposited tin oxide thin-film, and the Ar-plasma treatment partially transformed the tin oxide phase from SnO to SnO2 by oxidation. The resistivity of the tin oxide thin-film increased with the plasma-treatment time because of the reduced hole concentration. In addition, the root-mean-square roughness of the tin oxide thin-film decreased as the plasma-treatment time increased. The p-type oxide TFT with an Ar-plasma-treated tin oxide thin-film exhibited excellent electrical performance with a high current on-off ratio (5.2 × 106) and a low off-current (1.2 × 10-12 A), which demonstrates that the low-temperature Ar-plasma treatment is a simple and effective method for improving the electrical performance of p-type tin oxide TFTs.

  9. The capability of high field MRI in demonstrating post-mortem fetal brains at different gestational age

    International Nuclear Information System (INIS)

    Zhang Zhonghe; Liu Shuwei; Lin Xiangtao; Gen Hequn; Teng Gaojun; Fang Fang; Zang Fengchao; Yu Taifei; Zhao Bin

    2009-01-01

    Objective: To study the capability of high field MRI in demonstrating the post-mortem fetal brains at different gestational age (GA). Methods: One hundred and eight post-mortem fetal brains of 14-40 weeks GA were evaluated by 3.0 T MRI. Eleven brains of 14 to 27 weeks GA with good 3.0 T MRI images were chosen and scanned by 7.0 T MRI. The developing sulci, layered structures of fetal cerebral cortex and basal nuclei were evaluated on MRI of different Tesla (3.0 T and 7.0 T) and their results analyzed. Results: On T 1 WI of 3.0 T MRI, the layered structures of fetal cerebral cortex were present at 14 weeks GA, the sulci were more accurately identified after 16 weeks GA. The basal nuclei were clearly distinguishable after 20 weeks CA, and these structures were better visualized as the GA increased. On T 2 WI of 7.0 T MRI, the sulci, layered structures of fetal cerebral cortex and basal nuclei were shown more clearly at the same GA when compared to 3.0 T, especially the sulci at the early developmental stages. Conclusions: T 1 WI of 3.0 T MRI could show the developing structures of post-mortem fetal brain well, but the T 2 WI of 7.0 T MRI were comparatively better. (authors)

  10. High-resolution dynamic angiography using flat-panel volume CT: feasibility demonstration for neuro and lower limb vascular applications

    Energy Technology Data Exchange (ETDEWEB)

    Mehndiratta, Amit [Massachusetts General Hospital, Department of Radiology, Harvard Medical School, Boston, MA (United States); University of Oxford, Institute of Biomedical Engineering and Keble College, Oxford (United Kingdom); Indian Institute of Technology Delhi and All India Institute of Medical Science, Centre for Biomedical Engineering, New Delhi (India); Rabinov, James D. [Massachusetts General Hospital, Interventional Neuroradiology, Harvard Medical School, Boston, MA (United States); Grasruck, Michael [Siemens Medical Solutions, Forchheim (Germany); Liao, Eric C. [Massachusetts General Hospital, Department of Plastic and Reconstructive Surgery and Center for Regenerative Medicine, Harvard Medical School, Boston, MA (United States); Crandell, David [Spaulding Rehabilitation Hospital, Department of Physical Medicine and Rehabilitation, Harvard Medical School, Charlestown, MA (United States); Gupta, Rajiv [Massachusetts General Hospital, Department of Radiology, Harvard Medical School, Boston, MA (United States)

    2015-07-15

    This paper evaluates a prototype flat-panel volume CT (fpVCT) for dynamic in vivo imaging in a variety of neurovascular and lower limb applications. Dynamic CTA was performed on 12 patients (neuro = 8, lower limb = 4) using an fpVCT with 120 kVp, 50 mA, rotation time varying from 8 to 19 s, and field of view of 25 x 25 x 18 cm{sup 3}. Four-dimensional data sets (i.e. 3D images over time) were reconstructed and reviewed. Dynamic CTA demonstrated sufficient spatio-temporal resolution to elucidate first-pass and recirculation dynamics of contrast bolus through neurovasclar pathologies and phasic blood flow though lower-limb vasculature and grafts. The high spatial resolution of fpVCT resulted in reduced partial volume and metal beam-hardening artefacts. This facilitated assessment of vascular lumen in the presence of calcified plaque and evaluation of fractures, especially in the presence of fixation hardware. Evaluation of arteriovenous malformation using dynamic fpVCT angiography was of limited utility. Dynamic CTA using fpVCT can visualize time-varying phenomena in neuro and lower limb vascular applications and has sufficient diagnostic imaging quality to evaluate a number of pathologies affecting these regions. (orig.)

  11. Demonstration of SCR technology for the control of NOx emissions from high-sulfur coal-fired utility boilers

    Energy Technology Data Exchange (ETDEWEB)

    Hinton, W.S. [W.S. Hinton and Associates, Cantonment, FL (United States); Maxwell, J.D.; Healy, E.C.; Hardman, R.R. [Southern Company Services, Inc., Birmingham, AL (United States); Baldwin, A.L. [Dept. of Energy, Pittsburgh, PA (United States)

    1997-12-31

    This paper describes the completed Innovative Clean Coal Technology project which demonstrated SCR technology for reduction of flue gas NO{sub x} emissions from a utility boiler burning US high-sulfur coal. The project was sponsored by the US Department of Energy, managed and co-funded by Southern Company Services, Inc. on behalf of the Southern Company, and also co-funded by the Electric Power Research Institute and Ontario Hydro. The project was located at Gulf Power Company`s Plant Crist Unit 5 (a 75 MW tangentially-fired boiler burning US coals that had a sulfur content ranging from 2.5--2.9%), near Pensacola, Florida. The test program was conducted for approximately two years to evaluate catalyst deactivation and other SCR operational effects. The SCR test facility had nine reactors: three 2.5 MW (5,000 scfm), and operated on low-dust flue gas. The reactors operated in parallel with commercially available SCR catalysts obtained from suppliers throughout the world. Long-term performance testing began in July 1993 and was completed in July 1995. A brief test facility description and the results of the project are presented in this paper.

  12. Dispersion relations for 1D high-gain FELs

    International Nuclear Information System (INIS)

    Webb, S.D.; Litvinenko, V.N.

    2010-01-01

    We present analytical results for the one-dimensional dispersion relation for high-gain FELs. Using kappa-n distributions, we obtain analytical relations between the dispersion relations for various order kappa distributions. Since an exact solution exists for the kappa-1 (Lorentzian) distribution, this provides some insight into the number of modes on the way to the Gaussian distribution.

  13. Design and operating features of the high-level waste vitrification system for the West Valley demonstration project

    International Nuclear Information System (INIS)

    Siemens, D.H.; Beary, M.M.; Barnes, S.M.; Berger, D.N.; Brouns, R.A.; Chapman, C.C.; Jones, R.M.; Peters, R.D.; Peterson, M.E.

    1986-03-01

    A liquid-fed joule-heated ceramic melter system is the reference process for immobilization of the high-level liquid waste in the US and several foreign countries. This system has been under development for over ten years at Pacific Northwest Laboratory and other national laboratories operated for the US Department of Energy. Pacific Northwest Laboratory contributed to this research through its Nuclear Waste Treatment Program and used applicable data to design and test melters and related systems using remote handling of simulated radioactive wastes. This report describes the equipment designed in support of the high-level waste vitrification program at West Valley, New York. Pacific Northwest Laboratory worked closely with West Valley Nuclear Services Company to design a liquid-fed ceramic melter, a liquid waste preparation and feed tank and pump, an off-gas treatment scrubber, and an enclosed turntable for positioning the waste canisters. Details of these designs are presented including the rationale for the design features and the alternatives considered

  14. High-resolution modeling of the western North American power system demonstrates low-cost and low-carbon futures

    International Nuclear Information System (INIS)

    Nelson, James; Johnston, Josiah; Mileva, Ana; Fripp, Matthias; Hoffman, Ian; Petros-Good, Autumn; Blanco, Christian; Kammen, Daniel M.

    2012-01-01

    Decarbonizing electricity production is central to reducing greenhouse gas emissions. Exploiting intermittent renewable energy resources demands power system planning models with high temporal and spatial resolution. We use a mixed-integer linear programming model – SWITCH – to analyze least-cost generation, storage, and transmission capacity expansion for western North America under various policy and cost scenarios. Current renewable portfolio standards are shown to be insufficient to meet emission reduction targets by 2030 without new policy. With stronger carbon policy consistent with a 450 ppm climate stabilization scenario, power sector emissions can be reduced to 54% of 1990 levels by 2030 using different portfolios of existing generation technologies. Under a range of resource cost scenarios, most coal power plants would be replaced by solar, wind, gas, and/or nuclear generation, with intermittent renewable sources providing at least 17% and as much as 29% of total power by 2030. The carbon price to induce these deep carbon emission reductions is high, but, assuming carbon price revenues are reinvested in the power sector, the cost of power is found to increase by at most 20% relative to business-as-usual projections. - Highlights: ► Intermittent generation necessitates high-resolution electric power system models. ► We apply the SWITCH planning model to the western North American grid. ► We explore carbon policy and resource cost scenarios through 2030. ► As the carbon price rises, coal generation is replaced with solar, wind, gas and/or nuclear generation ► A 450 ppm climate stabilization target can be met at a 20% or lower cost increase.

  15. Demonstration of suppressed phonon tunneling losses in phononic bandgap shielded membrane resonators for high-Q optomechanics.

    Science.gov (United States)

    Tsaturyan, Yeghishe; Barg, Andreas; Simonsen, Anders; Villanueva, Luis Guillermo; Schmid, Silvan; Schliesser, Albert; Polzik, Eugene S

    2014-03-24

    Dielectric membranes with exceptional mechanical and optical properties present one of the most promising platforms in quantum opto-mechanics. The performance of stressed silicon nitride nanomembranes as mechanical resonators notoriously depends on how their frame is clamped to the sample mount, which in practice usually necessitates delicate, and difficult-to-reproduce mounting solutions. Here, we demonstrate that a phononic bandgap shield integrated in the membrane's silicon frame eliminates this dependence, by suppressing dissipation through phonon tunneling. We dry-etch the membrane's frame so that it assumes the form of a cm-sized bridge featuring a 1-dimensional periodic pattern, whose phononic density of states is tailored to exhibit one, or several, full band gaps around the membrane's high-Q modes in the MHz-range. We quantify the effectiveness of this phononic bandgap shield by optical interferometry measuring both the suppressed transmission of vibrations, as well as the influence of frame clamping conditions on the membrane modes. We find suppressions up to 40 dB and, for three different realized phononic structures, consistently observe significant suppression of the dependence of the membrane's modes on sample clamping-if the mode's frequency lies in the bandgap. As a result, we achieve membrane mode quality factors of 5 × 10(6) with samples that are tightly bolted to the 8 K-cold finger of a cryostat. Q × f -products of 6 × 10(12) Hz at 300 K and 14 × 10(12) Hz at 8 K are observed, satisfying one of the main requirements for optical cooling of mechanical vibrations to their quantum ground-state.

  16. Demonstrating the Uneven Importance of Fine-Scale Forest Structure on Snow Distributions using High Resolution Modeling

    Science.gov (United States)

    Broxton, P. D.; Harpold, A. A.; van Leeuwen, W.; Biederman, J. A.

    2016-12-01

    Quantifying the amount of snow in forested mountainous environments, as well as how it may change due to warming and forest disturbance, is critical given its importance for water supply and ecosystem health. Forest canopies affect snow accumulation and ablation in ways that are difficult to observe and model. Furthermore, fine-scale forest structure can accentuate or diminish the effects of forest-snow interactions. Despite decades of research demonstrating the importance of fine-scale forest structure (e.g. canopy edges and gaps) on snow, we still lack a comprehensive understanding of where and when forest structure has the largest impact on snowpack mass and energy budgets. Here, we use a hyper-resolution (1 meter spatial resolution) mass and energy balance snow model called the Snow Physics and Laser Mapping (SnowPALM) model along with LIDAR-derived forest structure to determine where spatial variability of fine-scale forest structure has the largest influence on large scale mass and energy budgets. SnowPALM was set up and calibrated at sites representing diverse climates in New Mexico, Arizona, and California. Then, we compared simulations at different model resolutions (i.e. 1, 10, and 100 m) to elucidate the effects of including versus not including information about fine scale canopy structure. These experiments were repeated for different prescribed topographies (i.e. flat, 30% slope north, and south-facing) at each site. Higher resolution simulations had more snow at lower canopy cover, with the opposite being true at high canopy cover. Furthermore, there is considerable scatter, indicating that different canopy arrangements can lead to different amounts of snow, even when the overall canopy coverage is the same. This modeling is contributing to the development of a high resolution machine learning algorithm called the Snow Water Artificial Network (SWANN) model to generate predictions of snow distributions over much larger domains, which has implications

  17. SOFC - Manufacture of stacks for test and demonstration related activities, stack and system tests and identification of end user requirements. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Jacobsen, Joachim; Primdahl, S.; Boegh Elmose, H.; Weineisen, H.; Richter, A.

    2008-11-15

    The aim of the project was to solve the technical challenges in relation to stack functionality in connection with operation of multi stack assemblies under realistic operating conditions. It was the intention to make a targeted effort with the aim of developing a high performance stack technology suitable for both small and large units. An important part of the project was the testing of stack assemblies up to 10 kW power range with relevant fuel and realistic operation condition in the test facility at HC OErstedvaerket. The manufacturing of stacks in the project was as planned a number of stacks (70 kW) for use in demonstration projects both for single stacks and for multi stack assemblies. The start up of the work on the SOFC test facility at HC OErstedsvaerket (HCV) was delayed due to a late delivery of the unit from the PSO 6385 project. A number of unforeseen events during the project have meant that the SOFC test facility at HCV has not until now been ready for performing tests. The experience gained from the operation of a 20 kW Alpha unit in a co-operation between TOFC and Waertsilae now provides an important contribution to the future multi stack assemblies. The work on identification of end user requirements has resulted in a number of different development priorities for the m-CHP and the Distributed Generation market segments. (au)

  18. Tested Demonstrations.

    Science.gov (United States)

    Gilbert, George L.

    1983-01-01

    An apparatus is described in which effects of pressure, volume, and temperature changes on a gas can be observed simultaneously. Includes use of the apparatus in demonstrating Boyle's, Gay-Lussac's, and Charles' Laws, attractive forces, Dalton's Law of Partial pressures, and in illustrating measurable vapor pressures of liquids and some solids.…

  19. Tested Demonstrations.

    Science.gov (United States)

    Gilbert, George L., Ed.

    1987-01-01

    Describes two demonstrations to illustrate characteristics of substances. Outlines a method to detect the changes in pH levels during the electrolysis of water. Uses water pistols, one filled with methane gas and the other filled with water, to illustrate the differences in these two substances. (TW)

  20. TU-FG-209-05: Demonstration of the Line Focus Principle Using the Generalized Measured-Relative Object Detectability (GM-ROD) Metric

    Energy Technology Data Exchange (ETDEWEB)

    Russ, M; Shankar, A; Lau, A; Bednarek, D; Rudin, S [University at Buffalo (SUNY), Buffalo, NY (United States)

    2016-06-15

    Purpose: Demonstrate and quantify the augmented resolution due to focalspot size decrease in images acquired on the anode side of the field, for both small and medium (0.3 and 0.6mm) focal-spot sizes using the experimental task-based GM-ROD metric. Theoretical calculations have shown that a medium focal-spot can achieve the resolution of a small focal-spot if acquired with a tilted anode, effectively providing a higher-output small focal-spot. Methods: The MAF-CMOS (micro-angiographic fluoroscopic complementary-metal-oxide semiconductor) detector (75µm pixel pitch) imaged two copper wire segments of different diameter and a pipeline stent at the central axis and on the anode side of the beam, achieved by tilting the x-ray C-arm (Toshiba Infinix) to 6° and realigning the detector with the perpendicular ray to correct for x-ray obliquity. The relative gain in resolution was determined using the GM-ROD metric, which compares images on the basis of the Fourier transform of the image and the measured NNPS. To emphasize the geometric unsharpness, images were acquired at a magnification of two. Results: Images acquired on the anode side were compared to those acquired on the central axis with the same target-area focal-spot to consider the effect of an angled tube, and for all three objects the advantage of the smaller effective focal-spot was clear, showing a maximum improvement of 36% in GM-ROD. The images obtained with the small focal-spot at the central axis were compared to those of the medium focal-spot at the anode side and, for all objects, the relative performance was comparable. Conclusion: For three objects, the GM-ROD demonstrated the advantage of the anode side focal-spot. The comparable performance of the medium focal-spot on the anode side will allow for a high-output small focal-spot; a necessity in endovascular image-guided interventions. Partial support from an NIH grant R01EB002873 and an equipment grant from Toshiba Medical Systems Corp.

  1. TU-FG-209-05: Demonstration of the Line Focus Principle Using the Generalized Measured-Relative Object Detectability (GM-ROD) Metric

    International Nuclear Information System (INIS)

    Russ, M; Shankar, A; Lau, A; Bednarek, D; Rudin, S

    2016-01-01

    Purpose: Demonstrate and quantify the augmented resolution due to focalspot size decrease in images acquired on the anode side of the field, for both small and medium (0.3 and 0.6mm) focal-spot sizes using the experimental task-based GM-ROD metric. Theoretical calculations have shown that a medium focal-spot can achieve the resolution of a small focal-spot if acquired with a tilted anode, effectively providing a higher-output small focal-spot. Methods: The MAF-CMOS (micro-angiographic fluoroscopic complementary-metal-oxide semiconductor) detector (75µm pixel pitch) imaged two copper wire segments of different diameter and a pipeline stent at the central axis and on the anode side of the beam, achieved by tilting the x-ray C-arm (Toshiba Infinix) to 6° and realigning the detector with the perpendicular ray to correct for x-ray obliquity. The relative gain in resolution was determined using the GM-ROD metric, which compares images on the basis of the Fourier transform of the image and the measured NNPS. To emphasize the geometric unsharpness, images were acquired at a magnification of two. Results: Images acquired on the anode side were compared to those acquired on the central axis with the same target-area focal-spot to consider the effect of an angled tube, and for all three objects the advantage of the smaller effective focal-spot was clear, showing a maximum improvement of 36% in GM-ROD. The images obtained with the small focal-spot at the central axis were compared to those of the medium focal-spot at the anode side and, for all objects, the relative performance was comparable. Conclusion: For three objects, the GM-ROD demonstrated the advantage of the anode side focal-spot. The comparable performance of the medium focal-spot on the anode side will allow for a high-output small focal-spot; a necessity in endovascular image-guided interventions. Partial support from an NIH grant R01EB002873 and an equipment grant from Toshiba Medical Systems Corp.

  2. Cosmogenically-produced isotopes in natural and enriched high-purity germanium detectors for the MAJORANA DEMONSTRATOR

    Science.gov (United States)

    Gilliss, Thomas; MAJORANA DEMONSTRATOR Collaboration

    2017-01-01

    The MAJORANA DEMONSTRATOR advances toward measurements of the neutrinoless double-beta decay of 76Ge. Detectors employed in the DEMONSTRATOR are subject to cosmogenic spallation during production and processing, resulting in activation of certain long-lived radioisotopes. Activation of these cosmogenic isotopes is mitigated by shielded storage of detectors and through underground operation of the DEMONSTRATOR at the 4850 ft level of the Sanford Underground Research Facility. In this work, we explore the appearance and reduction of cosmogenic contributions to the DEMONSTRATOR background spectrum. This work is supported by the U.S. Department of Energy, Office of Science, Office of Nuclear Physics, the Particle Astrophysics and Nuclear Physics Programs of the National Science Foundation, and the Sanford Underground Research Facility.

  3. Device Demonstration

    Science.gov (United States)

    2006-12-31

    the entire unit is assembled by high temperature brazing using a gold- nickel alloy. Figure 18. Photograph of a typical DPF anode that has been cross... Molybdenum was chosen for the cathode tube material because it has a low sputtering coefficient, and it’s high temperature properties.. The tubes are...Set (Write a"") "* Apply current to raise memory element temperature to promote crystallization "* Crystalline state = low resistance = high current

  4. Alcohol-Related Problems And High Risk Sexual Behaviour In ...

    African Journals Online (AJOL)

    There was a significant association between alcohol-related problems and risky sexual behavior. Alcohol-related problems are fairly common in people already infected with HIV/AIDS and are associated with high-risk sexual behavior. Thus, screening and treatment should be part of an effective HIV intervention program.

  5. Comparing Demonstratives in Kwa

    African Journals Online (AJOL)

    This paper is a comparative study of demonstrative forms in three K wa languages, ... relative distance from the deictic centre, such as English this and that, here and there. ... Mostly, the referents of demonstratives are 'activated' or at least.

  6. Demonstration of a strategy for product purification by high-gradient magnetic fishing: Recovery of superoxide dismutase from unconditioned whey

    DEFF Research Database (Denmark)

    Meyer, A.; Hansen, D.B.; Goncalves Gomes, Claudia Sofia

    2005-01-01

    and solids; (iv) elution of the target protein; and (v) recovery of the eluted supports from the HGMF rig. Efficient recovery of SOD was demonstrated at similar to50-fold increased scale (cf. magnetic rack studies) in three separate HGMF experiments, and in the best of these (run 3) an SOD yield of >85...

  7. The Belgian demonstration programme for the disposal of high-level and long-lived radioactive waste

    International Nuclear Information System (INIS)

    Bernier, F.; Demarche, M.

    2006-01-01

    The EIG EURIDICE is responsible for performing large-scale tests, technical demonstrations and experiments so as to assess the feasibility of a final disposal of vitrified radioactive waste in deep clay layers. This programme is part of the Belgian Research and Development programme managed by ONDRAF/NIRAS. The research infrastructure includes the Underground Research Facilities HADES (URF HADES) in the Boom Clay geological formation and surface facilities. The achievements of the demonstration programme are the demonstration of the construction of shafts and galleries at industrial scale, the characterisation of the hydro-mechanical response of the host rock, and the 'OPHELIE mock-up' a large scale hydration test under thermal load of pre-fabricated bentonite blocks. The future works will consist mainly in the realisation of the 'PRACLAY experiments' including a large scale heater test. The results of this test will constitute an important input for the Safety and Feasibility Cases 1 (SFC-1, 2013) and 2 (SFC-2, 2020). (author)

  8. Hematoxylin and eosin stain shows a high sensitivity but sub-optimal specificity in demonstrating iron pigment in liver biopsies.

    Science.gov (United States)

    Alwahaibi, Nasar Yousuf; Alkhatri, Azza Sarhan; Kumar, Johanes Selva

    2015-01-01

    Perls' stain is routinely used to demonstrate iron in liver biopsies. We tested the hypothesis that it may be unnecessary in cases, where no iron or another similar pigment was seen on the routine hematoxylin and eosin (H and E) stained section. The aim of this study was to evaluate the efficiency of H and E stain in demonstrating iron in liver biopsies as well as to determine the possibility of replacing Perls' stain with H and E stain. Two hundred pairs of slides of liver biopsies were taken from the archival files of the Department of Pathology from 2006 to 2011. Perls' and H and E slides were independently reviewed for the presence of iron. Hundred and one cases showed the presence of iron using H and E stain. 84 of 86 cases showed positive iron using both Perls' and H and E stains. Seventeen cases were positive using H and E stain but negative with Perls'. Only two cases did not show the presence of iron using H and E stain. Ninety-seven cases were negative using both Perls' and H and E stains. H and E stain showed a sensitivity, specificity, accuracy, positive predictive valve, and negative predictive value of 97.67%, 85.08%, 90.5%, 83.16%, and 97.98%, respectively. We demonstrate that the H and E stain is a sensitive method to detect iron pigment in liver biopsies, particularly when present in large quantities. A negative H and E stain might obviate the need for extra Perls' staining, thus saving costs and shortening report turn-around times.

  9. Relative safety profiles of high dose statin regimens

    Directory of Open Access Journals (Sweden)

    Carlos Escobar

    2008-06-01

    Full Text Available Carlos Escobar, Rocio Echarri, Vivencio BarriosDepartment of Cardiology, Hospital Ramón y Cajal, Madrid, SpainAbstract: Recent clinical trials recommend achieving a low-density lipoprotein cholesterol level of <100 mg/dl in high-risk and <70 mg/dl in very high risk patients. To attain these goals, however, many patients will need statins at high doses. The most frequent side effects related to the use of statins, myopathy, rhabdomyolysis, and increased levels of transaminases, are unusual. Although low and moderate doses show a favourable profile, there is concern about the tolerability of higher doses. During recent years, numerous trials to analyze the efficacy and tolerability of high doses of statins have been published. This paper updates the published data on the safety of statins at high doses.Keywords: statins, high doses, tolerability, liver, muscle

  10. Processing of Ni30Pt20Ti50 High-Temperature Shape-Memory Alloy Into Thin Rod Demonstrated

    Science.gov (United States)

    Noebe, Ronald D.; Draper, Susan L.; Biles, Tiffany A.; Leonhardt, Todd

    2005-01-01

    High-temperature shape-memory alloys (HTSMAs) based on nickel-titanium (NiTi) with significant ternary additions of palladium (Pd), platinum (Pt), gold (Au), or hafnium (Hf) have been identified as potential high-temperature actuator materials for use up to 500 C. These materials provide an enabling technology for the development of "smart structures" used to control the noise, emissions, or efficiency of gas turbine engines. The demand for these high-temperature versions of conventional shape-memory alloys also has been growing in the automotive, process control, and energy industries. However these materials, including the NiPtTi alloys being developed at the NASA Glenn Research Center, will never find widespread acceptance unless they can be readily processed into useable forms.

  11. Biophysical modeling of high field diffusion MRI demonstrates micro-structural aberration in chronic mild stress rat brain

    DEFF Research Database (Denmark)

    Khan, Ahmad Raza; Chuhutin, Andrey; Wiborg, Ove

    2016-01-01

    anhedonia is considered to be a realistic model of depression in studies of animal subjects. Stereological and neuronal tracing techniques have demonstrated persistent remodeling of microstructure in hippocampus, prefrontal cortex and amygdala of CMS brains. Recent developments in diffusion MRI (d...... microstructure in the hippocampus, prefrontal cortex, caudate putamen and amygdala regions of CMS rat brains by comparison to brains from normal controls. To validate findings of CMS induced microstructural alteration, histology was performed to determine neurite, nuclear and astrocyte density. d-MRI based...... neurite density and tensor-based mean kurtosis (MKT) were significantly higher, while mean diffusivity (MD), extracellular diffusivity (Deff) and intra-neurite diffusivity(DL) were significantly lower in the amygdala of CMS rat brains. Deff was also significantly lower in the hippocampus and caudate...

  12. Materials development and field demonstration of high-recycled-content concrete for energy-efficient building construction; FINAL

    International Nuclear Information System (INIS)

    Ostowari, Ken; Nosson, Ali

    2000-01-01

    The project developed high-recycled-content concrete material with balanced structural and thermal attributes for use in energy-efficient building construction. Recycled plastics, tire, wool, steel and concrete were used as replacement for coarse aggregates in concrete and masonry production. With recycled materials the specific heat and thermal conductivity of concrete could be tailored to enhance the energy-efficiency of concrete buildings. A comprehensive field project was implemented which confirmed the benefits of high-recycled-content concrete for energy-efficient building construction

  13. Summary of high field diffusion MRI and microscopy data demonstrate microstructural aberration in chronic mild stress rat brain

    DEFF Research Database (Denmark)

    Khan, Ahmad Raza; Chuhutin, Andrey; Wiborg, Ove

    2016-01-01

    amygdala of the same brain hemispheres is also included with three different stains: DiI and Hoechst stained microscopic images (confocal microscopy) andALDH1L1 antibody based immunohistochemistry.These stains may be used to evaluate neurite density (DiI), nuclear density (Hoechst) and astrocytic density...... (ALDH1L1). This combination of high field diffusion data and high resolution images from microscopy enables comparison of microstructural parameters derived from diffusion MRIto histological microstructure. The data provided here is used in the article (Jespersen, 2016) [1]....

  14. School-Related Factors Affecting High School Seniors' Methamphetamine Use

    Science.gov (United States)

    Stanley, Jarrod M.; Lo, Celia C.

    2009-01-01

    Data from the 2005 Monitoring the Future survey were used to examine relationships between school-related factors and high school seniors' lifetime methamphetamine use. The study applied logistic regression techniques to evaluate effects of social bonding variables and social learning variables on likelihood of lifetime methamphetamine use. The…

  15. Small-scale integrated demonstration of high-level radioactive waste processing and vitrification using actual SRP waste

    International Nuclear Information System (INIS)

    Woolsey, G.B.; Baumgarten, P.K.; Eibling, R.E.; Ferguson, R.B.

    1981-01-01

    A small-scale pilot plant for chemical processing and vitrification of actual high-level waste has been constructed at the Savannah River Laboratory (SRL). This fully integrated facility has been constructed in six shielded cells and has eight major unit operations. Equipment performance and processing characteristics of the unit operations are reported

  16. Phylogenetic and Functional Analysis of Metagenome Sequence from High-Temperature Archaeal Habitats Demonstrate Linkages between Metabolic Potential and Geochemistry

    DEFF Research Database (Denmark)

    Inskeep, William P; Jay, Zackary J; Herrgard, Markus

    2013-01-01

    Geothermal habitats in Yellowstone National Park (YNP) provide an unparalleled opportunity to understand the environmental factors that control the distribution of archaea in thermal habitats. Here we describe, analyze, and synthesize metagenomic and geochemical data collected from seven high-tem...

  17. Closure of digital arteries in high vascular tone states as demonstrated by measurement of systolic blood pressure in the fingers

    DEFF Research Database (Denmark)

    Krähenbühl, B; Nielsen, S L; Lassen, N A

    1977-01-01

    Finger systolic blood pressure (FSP) was measured indirectly in normal subjects and patients with primary Raynaud phenomenon by applying a thin-walled plastic cuff around the finger and a strain gauge more distally to detect volume changes. Inducing a high vascular tone in one or more fingers by ...

  18. How to calculate clearance of highly protein-bound drugs during continuous venovenous hemofiltration demonstrated with flucloxacillin.

    Science.gov (United States)

    Meyer, Brigitte; Ahmed el Gendy, Salwa; Delle Karth, Georg; Locker, Gottfried J; Heinz, Gottfried; Jaeger, Walter; Thalhammer, Florian

    2003-01-01

    Flucloxacillin is an important antimicrobial drug in the treatment of infections with Staphylococcus aureus and therefore is often used in staphylococcal infections. Furthermore, flucloxacillin has a high protein binding rate as for example ceftriaxone or teicoplanin--drugs which have formerly been characterized as not being dialyzable. The pharmacokinetic parameters of 4.0 g flucloxacillin every 8 h were examined in 10 intensive care patients during continuous venovenous hemofiltration (CVVH) using a polyamide capillary hemofilter. In addition, the difficulty of calculating the hemofiltration clearance of a highly protein-bound drug is described. Flucloxacillin serum levels were significantly lowered (56.9 +/- 24.0%) even though only 15% of the drug was detected in the ultrafiltrate. Elimination half-life, total body clearance and sieving coefficient were 4.9 +/- 0.7 h, 117.2 +/- 79.1 ml/min and 0.21 +/- 0.09, respectively. These discrepancies can be explained by the high protein binding of flucloxacillin, the adsorbing property of polyamide and the equation in order to calculate hemofiltration clearance. The unbound fraction of a 4.0 g flucloxacillin dosage facilitates time above the minimum inhibitory concentration (T > MIC) of 60% only for strains up to a minimum inhibitory concentration (MIC) of 0.5 mg/l. Based on the data of this study, we conclude that intensive care patients with staphylococcal infections on CVVH should be treated with 4.0 g flucloxacillin every 8 h which was safe and well tolerated. Moreover, further studies with highly protein-bound drugs are recommended to check the classical 'hemodialysis' equation as the standard equation in calculating the CVVH clearance of highly protein-bound drugs. Copyright 2003 S. Karger AG, Basel

  19. Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation

    DEFF Research Database (Denmark)

    Weinert, Brian T; Wagner, Sebastian A; Horn, Heiko

    2011-01-01

    Posttranslational modification of proteins by acetylation and phosphorylation regulates most cellular processes in living organisms. Surprisingly, the evolutionary conservation of phosphorylated serine and threonine residues is only marginally higher than that of unmodified serines and threonines....... With high-resolution mass spectrometry, we identified 1981 lysine acetylation sites in the proteome of Drosophila melanogaster. We used data sets of experimentally identified acetylation and phosphorylation sites in Drosophila and humans to analyze the evolutionary conservation of these modification sites...... between flies and humans. Site-level conservation analysis revealed that acetylation sites are highly conserved, significantly more so than phosphorylation sites. Furthermore, comparison of lysine conservation in Drosophila and humans with that in nematodes and zebrafish revealed that acetylated lysines...

  20. Closure of digital arteries in high vascular tone states as demonstrated by measurement of systolic blood pressure in the fingers

    DEFF Research Database (Denmark)

    Krähenbühl, B; Nielsen, S L; Lassen, N A

    1977-01-01

    by direct cooling or intra-arterial noradrenaline infusion caused a marked drop in FSP in the exposed fingers, but not in the non-exposed fingers of the same hand. The fact that the non-exposed fingers retained the normal (arm systolic) pressure level is taken to indicate that palmar arch blood pressure......Finger systolic blood pressure (FSP) was measured indirectly in normal subjects and patients with primary Raynaud phenomenon by applying a thin-walled plastic cuff around the finger and a strain gauge more distally to detect volume changes. Inducing a high vascular tone in one or more fingers...... also remained normal. In the high vascular tone state, a large transmural pressure difference must apparently be established before the digital arteries are forced open. The lowered opening pressure constitutes a manifestation of the closure phenomenon of the digital arteries described in patients...

  1. Demonstration of the TRUEX process for the treatment of actual high activity tank waste at the INEEL using centrifugal contactors

    International Nuclear Information System (INIS)

    Law, J.D.; Brewer, K.N.; Todd, T.A.; Olson, L.G.

    1997-01-01

    The Idaho Chemical Processing Plant (ICPP), located at the Idaho National Engineering and Environmental Laboratory (INEEL), formerly reprocessed spent nuclear fuel to recover fissionable uranium. The radioactive raffinates from the solvent extraction uranium recovery processes were converted to granular solids (calcine) in a high temperature fluidized bed. A secondary liquid waste stream was generated during the course of reprocessing, primarily from equipment decontamination between campaigns and solvent wash activities. This acidic tank waste cannot be directly calcined due to the high sodium content and has historically been blended with reprocessing raffinates or non-radioactive aluminum nitrate prior to calcination. Fuel reprocessing activities are no longer being performed at the ICPP, thereby eliminating the option of waste blending to deplete the waste inventory. Currently, approximately 5.7 million liters of high-activity waste are temporarily stored at the ICPP in large underground stainless-steel tanks. The United States Environmental Protection Agency and the Idaho Department of Health and Welfare filed a Notice of Noncompliance in 1992 contending some of the underground waste storage tanks do not meet secondary containment. As part of a 1995 agreement between the State of Idaho, the Department of Energy, and the Department of Navy, the waste must be removed from the tanks by 2012. Treatment of the tank waste inventories by partitioning the radionuclides and immobilizing the resulting high-activity and low-activity waste streams is currently under evaluation. A recent peer review identified the most promising radionuclide separation technologies for evaluation. The Transuranic Extraction-(TRUEX) process was identified as a primary candidate for separation of the actinides from ICPP tank waste

  2. In Vitro Measles Virus Infection of Human Lymphocyte Subsets Demonstrates High Susceptibility and Permissiveness of both Naive and Memory B Cells.

    Science.gov (United States)

    Laksono, Brigitta M; Grosserichter-Wagener, Christina; de Vries, Rory D; Langeveld, Simone A G; Brem, Maarten D; van Dongen, Jacques J M; Katsikis, Peter D; Koopmans, Marion P G; van Zelm, Menno C; de Swart, Rik L

    2018-04-15

    Measles is characterized by a transient immune suppression, leading to an increased risk of opportunistic infections. Measles virus (MV) infection of immune cells is mediated by the cellular receptor CD150, expressed by subsets of lymphocytes, dendritic cells, macrophages, and thymocytes. Previous studies showed that human and nonhuman primate memory T cells express higher levels of CD150 than naive cells and are more susceptible to MV infection. However, limited information is available about the CD150 expression and relative susceptibility to MV infection of B-cell subsets. In this study, we assessed the susceptibility and permissiveness of naive and memory T- and B-cell subsets from human peripheral blood or tonsils to in vitro MV infection. Our study demonstrates that naive and memory B cells express CD150, but at lower frequencies than memory T cells. Nevertheless, both naive and memory B cells proved to be highly permissive to MV infection. Furthermore, we assessed the susceptibility and permissiveness of various functionally distinct T and B cells, such as helper T (T H ) cell subsets and IgG- and IgA-positive memory B cells, in peripheral blood and tonsils. We demonstrated that T H 1T H 17 cells and plasma and germinal center B cells were the subsets most susceptible and permissive to MV infection. Our study suggests that both naive and memory B cells, along with several other antigen-experienced lymphocytes, are important target cells of MV infection. Depletion of these cells potentially contributes to the pathogenesis of measles immune suppression. IMPORTANCE Measles is associated with immune suppression and is often complicated by bacterial pneumonia, otitis media, or gastroenteritis. Measles virus infects antigen-presenting cells and T and B cells, and depletion of these cells may contribute to lymphopenia and immune suppression. Measles has been associated with follicular exhaustion in lymphoid tissues in humans and nonhuman primates, emphasizing the

  3. Biofluid metabotyping of occupationally exposed subjects to air pollution demonstrates high oxidative stress and deregulated amino acid metabolism

    Science.gov (United States)

    Pradhan, Surya Narayan; Das, Aleena; Meena, Ramovatar; Nanda, Ranjan Kumar; Rajamani, Paulraj

    2016-10-01

    Occupational exposure to air pollution induces oxidative stress and prolonged exposure increases susceptibility to cardiovascular and respiratory diseases in several working groups. Biofluid of these subjects may reflect perturbed metabolic phenotypes. In this study we carried out a comparative molecular profiling study using parallel biofluids collected from subjects (n = 85) belonging to auto rickshaw drivers (ARD), traffic cops (TC) and office workers (OW). Higher levels of oxidative stress and inflammation markers in serum of ARD subjects were observed as compared to OW and TC. Uni and multivariate analyses of metabolites identified in urine by 1H NMR revealed 11 deregulated molecules in ARD subjects and involved in phenylalanine, histidine, arginine and proline metabolism. Despite contribution of confounding factors like exposure period, dietary factors including smoking and alcohol status, our results demonstrate existence of exposure specific metabotypes in biofluids of ARD, OW and TC groups. Monitoring serum oxidative stress and inflammation markers and urine metabolites by NMR may be useful to characterize perturbed metabolic phenotypes in populations exposed to urban traffic air pollution.

  4. Integrated analyses of microRNAs demonstrate their widespread influence on gene expression in high-grade serous ovarian carcinoma.

    Science.gov (United States)

    Creighton, Chad J; Hernandez-Herrera, Anadulce; Jacobsen, Anders; Levine, Douglas A; Mankoo, Parminder; Schultz, Nikolaus; Du, Ying; Zhang, Yiqun; Larsson, Erik; Sheridan, Robert; Xiao, Weimin; Spellman, Paul T; Getz, Gad; Wheeler, David A; Perou, Charles M; Gibbs, Richard A; Sander, Chris; Hayes, D Neil; Gunaratne, Preethi H

    2012-01-01

    The Cancer Genome Atlas (TCGA) Network recently comprehensively catalogued the molecular aberrations in 487 high-grade serous ovarian cancers, with much remaining to be elucidated regarding the microRNAs (miRNAs). Here, using TCGA ovarian data, we surveyed the miRNAs, in the context of their predicted gene targets. Integration of miRNA and gene patterns yielded evidence that proximal pairs of miRNAs are processed from polycistronic primary transcripts, and that intronic miRNAs and their host gene mRNAs derive from common transcripts. Patterns of miRNA expression revealed multiple tumor subtypes and a set of 34 miRNAs predictive of overall patient survival. In a global analysis, miRNA:mRNA pairs anti-correlated in expression across tumors showed a higher frequency of in silico predicted target sites in the mRNA 3'-untranslated region (with less frequency observed for coding sequence and 5'-untranslated regions). The miR-29 family and predicted target genes were among the most strongly anti-correlated miRNA:mRNA pairs; over-expression of miR-29a in vitro repressed several anti-correlated genes (including DNMT3A and DNMT3B) and substantially decreased ovarian cancer cell viability. This study establishes miRNAs as having a widespread impact on gene expression programs in ovarian cancer, further strengthening our understanding of miRNA biology as it applies to human cancer. As with gene transcripts, miRNAs exhibit high diversity reflecting the genomic heterogeneity within a clinically homogeneous disease population. Putative miRNA:mRNA interactions, as identified using integrative analysis, can be validated. TCGA data are a valuable resource for the identification of novel tumor suppressive miRNAs in ovarian as well as other cancers.

  5. Changing Relations between High Castes and Tamang in Melamchi Valley

    Directory of Open Access Journals (Sweden)

    Binod Pokharel

    2011-04-01

    Full Text Available This paper is about the processes of transformation of social relations between high caste groups and Tamang in Melamchi Valley for the period of 1980-2010. Development interventions made by government of Nepal and (I NGOs, a decade long undergoing Melamchi Water Supply Project and labor migration are major factors for ongoing changes in the study area. Spread of literacy classes and primary education, availability of credit institutions, introduction of modern farming, road networks, seasonal out migration from the area, etc. primarily define new relations among the groups. Borrowing and lending money were one of the basis of high caste and Tamang relation in past. The latter was regarded as borrower loan from first one. Before 1980s, money and agriculture commodities were controlled by few rich and high castes people. Cash income from various sources made enable the Tamang to stand on an equal footing with high caste people. Open political economy and liberal policy for issuing pass port in 1990s and after that encourage the people to diversify the destination of seasonal migration from India to Gulf countries and East Asia. Various processes of socio-economic and political changes led to local peoples to seek their position and identity in the changing context. Discourse of Tamang, high castes and Dalit entered into the Valley along with the development resources of (INGO and political movements of the country. This made possible to Tamang and other disadvantage groups to define and redefine their ethnic identity. Keywords: High castes; Tamang; credit facilities; subsistence farming; identity construction; money lending; wage labor DOI: 10.3126/dsaj.v4i0.4513 Dhaulagiri Journal of Sociology and Anthropology Vol.4 2010 pp.65-84

  6. Flexible-Rotor Balancing Demonstration

    Science.gov (United States)

    Giordano, J.; Zorzi, E.

    1986-01-01

    Report describes method for balancing high-speed rotors at relatively low speeds and discusses demonstration of method on laboratory test rig. Method ensures rotor brought up to speeds well over 20,000 r/min smoothly, without excessive vibration amplitude at critical speeds or at operating speed.

  7. Arctic Sovereignty Disputes: International Relations Theory in the High North

    Science.gov (United States)

    2011-12-01

    Russians continue to retain their long-range strategic bombing fleets, consisting of the TU-160 Supersonic ( Blackjack ), an all-weather aircraft with...icebreakers, and the only operational heavy icebreaker, it is already beyond service life expectations and recently suffered a major engine failure...DISPUTES: INTERNATIONAL RELATIONS THEORY IN THE HIGH NORTH by Darrin D. Davis December 2011 Thesis Co-Advisors: Anne L. Clunan

  8. Electron spectroscopy on high-temperature superconductors and related compounds

    International Nuclear Information System (INIS)

    Knupfer, M.

    1994-01-01

    In the last two classes of materials have been discovered which distinguish themselves due to a transition into the superconducting state at relatively high temperatures. These are the cuprate superconductors and the alkali metal doped fullerenes. In this work the electronic structure of representatives of these materials, undoped and Ca-doped YBa 2 Cu 4 O 8 and A 3 C 60 (A=K, Rb), has been investigated using electron energy-loss spectroscopy and photoemission spectroscopy. (orig.) [de

  9. SOX2 anophthalmia syndrome: 12 new cases demonstrating broader phenotype and high frequency of large gene deletions.

    Science.gov (United States)

    Bakrania, P; Robinson, D O; Bunyan, D J; Salt, A; Martin, A; Crolla, J A; Wyatt, A; Fielder, A; Ainsworth, J; Moore, A; Read, S; Uddin, J; Laws, D; Pascuel-Salcedo, D; Ayuso, C; Allen, L; Collin, J R O; Ragge, N K

    2007-11-01

    Developmental eye anomalies, which include anophthalmia (absent eye) or microphthalmia (small eye) are an important cause of severe visual impairment in infants and young children. Heterozygous mutations in SOX2, a SOX1B-HMG box transcription factor, have been found in up to 10% of individuals with severe microphthalmia or anophthalmia and such mutations could also be associated with a range of non-ocular abnormalities. We performed mutation analysis on a new cohort of 120 patients with congenital eye abnormalities, mainly anophthalmia, microphthalmia and coloboma. Multiplex ligation-dependent probe amplification (MLPA) and fluorescence in situ hybridisation (FISH) were used to detect whole gene deletion. We identified four novel intragenic SOX2 mutations (one single base deletion, one single base duplication and two point mutations generating premature translational termination codons) and two further cases with the previously reported c.70del20 mutation. Of 52 patients with severe microphthalmia or anophthalmia analysed by MLPA, 5 were found to be deleted for the whole SOX2 gene and 1 had a partial deletion. In two of these, FISH studies identified sub-microscopic deletions involving a minimum of 328 Kb and 550 Kb. The SOX2 phenotypes include a patient with anophthalmia, oesophageal abnormalities and horseshoe kidney, and a patient with a retinal dystrophy implicating SOX2 in retinal development. Our results provide further evidence that SOX2 haploinsufficiency is a common cause of severe developmental ocular malformations and that background genetic variation determines the varying phenotypes. Given the high incidence of whole gene deletion we recommend that all patients with severe microphthalmia or anophthalmia, including unilateral cases be screened by MLPA and FISH for SOX2 deletions.

  10. Continuous assessment of land mapping accuracy at High Resolution from global networks of atmospheric and field observatories -concept and demonstration

    Science.gov (United States)

    Sicard, Pierre; Martin-lauzer, François-regis

    2017-04-01

    In the context of global climate change and adjustment/resilience policies' design and implementation, there is a need not only i. for environmental monitoring, e.g. through a range of Earth Observations (EO) land "products" but ii. for a precise assessment of uncertainties of the aforesaid information that feed environmental decision-making (to be introduced in the EO metadata) and also iii. for a perfect handing of the thresholds which help translate "environment tolerance limits" to match detected EO changes through ecosystem modelling. Uncertainties' insight means precision and accuracy's knowledge and subsequent ability of setting thresholds for change detection systems. Traditionally, the validation of satellite-derived products has taken the form of intensive field campaigns to sanction the introduction of data processors in Payload Data Ground Segments chains. It is marred by logistical challenges and cost issues, reason why it is complemented by specific surveys at ground-based monitoring sites which can provide near-continuous observations at a high temporal resolution (e.g. RadCalNet). Unfortunately, most of the ground-level monitoring sites, in the number of 100th or 1000th, which are part of wider observation networks (e.g. FLUXNET, NEON, IMAGINES) mainly monitor the state of the atmosphere and the radiation exchange at the surface, which are different to the products derived from EO data. In addition they are "point-based" compared to the EO cover to be obtained from Sentinel-2 or Sentinel-3. Yet, data from these networks, processed by spatial extrapolation models, are well-suited to the bottom-up approach and relevant to the validation of vegetation parameters' consistency (e.g. leaf area index, fraction of absorbed photosynthetically active radiation). Consistency means minimal errors on spatial and temporal gradients of EO products. Test of the procedure for land-cover products' consistency assessment with field measurements delivered by worldwide

  11. Double demonstration of oncogenic high risk human papilloma virus DNA and HPV-E7 protein in oral cancers.

    Science.gov (United States)

    Pannone, G; Santoro, A; Carinci, F; Bufo, P; Papagerakis, S M; Rubini, C; Campisi, G; Giovannelli, L; Contaldo, M; Serpico, R; Mazzotta, M; Lo Muzio, L

    2011-01-01

    Oncogenic HPVs are necessarily involved in cervical cancer but their role in oral carcinogenesis is debated. To detect HPV in oral cancer, 38 cases of formalin fixed-paraffin embedded OSCC were studied by both DNA genotyping (MY09/11 L1 consensus primers in combination with GP5-GP6 primer pair followed by sequencing) and immunohistochemistry (monoclonal Abs against capsid protein and HPV-E7 protein, K1H8 DAKO and clone 8C9 INVITROGEN, respectively). HPV-16 tonsil cancer was used as positive control. The overall prevalence of HPV infection in OSCCs was 10.5%. Amplification of DNA samples showed single HPV DNA infection in 3 cases (HPV16; HPV53; HPV70) and double infection in one case of cheek cancer (HPV31/HPV44). The overall HR-HPV prevalence was 7.5%. E-7 antigen was immunohistochemically detected in all HPV-positive cases. HPV+ OSCC cases showed an overall better outcome than HPV negative oral cancers, as evaluated by Kaplan-Meier curves. HPVs exert their oncogenic role after DNA integration, gene expression of E5, E6 and E7 loci and p53/pRb host proteins suppression. This study showed that HPV-E7 protein inactivating pRb is expressed in oral cancer cells infected by oncogenic HPV other than classical HR-HPV-16/18. Interestingly HPV-70, considered a low risk virus with no definite collocation in oncogenic type category, gives rise to the expression of HPV-E7 protein and inactivate pRb in oral cancer. HPV-70, as proved in current literature, is able to inactivates also p53 protein, promoting cell immortalization. HPV-53, classified as a possible high risk virus, expresses E7 protein in OSCC, contributing to oral carcinogenesis. We have identified among OSCCs, a subgroup characterized by HPV infection (10.5%). Finally, we have proved the oncogenic potential of some HPV virus types, not well known in literature.

  12. Establishing comparability and compatibility in the purity assessment of high purity zinc as demonstrated by the CCQM-P149 intercomparison

    Science.gov (United States)

    Vogl, Jochen; Kipphardt, Heinrich; Richter, Silke; Bremser, Wolfram; del Rocío Arvizu Torres, María; Manzano, Judith Velina Lara; Buzoianu, Mirella; Hill, Sarah; Petrov, Panayot; Goenaga-Infante, Heidi; Sargent, Mike; Fisicaro, Paola; Labarraque, Guillaume; Zhou, Tao; Turk, Gregory C.; Winchester, Michael; Miura, Tsutomu; Methven, Brad; Sturgeon, Ralph; Jährling, Reinhard; Rienitz, Olaf; Mariassy, Michal; Hankova, Zuzana; Sobina, Egor; Ivanovich Krylov, Anatoly; Anatolievich Kustikov, Yuri; Vladimirovich Smirnov, Vadim

    2018-04-01

    For the first time, an international comparison was conducted on the determination of the purity of a high purity element. Participants were free to choose any analytical approach appropriate for their institute’s applications and services. The material tested was a high purity zinc, which had earlier been assessed for homogeneity and previously used in CCQM-K72 for the determination of six defined metallic impurities. Either a direct metal assay of the Zn mass fraction was undertaken by EDTA titrimetry, or an indirect approach was used wherein all impurities, or at least the major ones, were determined and their sum subtracted from ideal purity of 100%, or 1 kg kg-1. Impurity assessment techniques included glow discharge mass spectrometry, inductively coupled plasma mass spectrometry and carrier gas hot extraction/combustion analysis. Up to 91 elemental impurities covering metals, non-metals and semi-metals/metalloids were quantified. Due to the lack of internal experience or experimental capabilities, some participants contracted external laboratories for specific analytical tasks, mainly for the analysis of non-metals. The reported purity, expressed as zinc mass fraction in the high purity zinc material, showed excellent agreement for all participants, with a relative standard deviation of 0.011%. The calculated reference value, w(Zn)  =  0.999 873 kg kg-1, was assigned an asymmetric combined uncertainty of  +0.000 025 kg kg-1 and  -0.000 028 kg kg-1. Comparability amongst participating metrology institutes is thus demonstrated for the purity determination of high purity metals which have no particular difficulties with their decomposition/dissolution process when solution-based analytical methods are used, or which do not have specific difficulties when direct analysis approaches are used. Nevertheless, further development is required in terms of uncertainty assessment, quantification of non-metals and the determination of purity

  13. Test results of full-scale high temperature superconductors cable models destined for a 36 kV, 2 kA(rms) utility demonstration

    DEFF Research Database (Denmark)

    Daumling, M.; Rasmussen, C.N.; Hansen, F.

    2001-01-01

    Power cable systems using high temperature superconductors (HTS) are nearing technical feasibility. This presentation summarises the advancements and status of a project aimed at demonstrating a 36 kV, 2 kA(rms) AC cable system by installing a 30 m long full-scale functional model in a power...

  14. Perception of parents as demonstrating the inherent merit of their values: relations with self-congruence and subjective well-being.

    Science.gov (United States)

    Yu, Shi; Assor, Avi; Liu, Xiangping

    2015-02-01

    This study focuses on the parenting practice of inherent value demonstration (IVD), involving parents' tendency to express their values in behaviours and appear satisfied and vital while doing so. Data from Chinese college students (n = 89) confirmed the hypothesis that offspring's perception of their parents as engaged in IVD predicts offspring's subjective well-being (SWB) through sense of self-congruence. Importantly, these relations emerged also when controlling for fundamental autonomy-supportive (FAS) parenting practices such as taking children's perspective, minimising control and allowing choice. These findings are consistent with the view that parents concerned with their children's sense of autonomy may do well to engage in IVD in addition to more fundamental autonomy-supportive practices. Future research may examine the role of IVD in promoting authentic values that serve as an internal compass that guides children to act in ways that feel self-congruent. © 2014 International Union of Psychological Science.

  15. Nonlinear generalization of special relativity at very high energies

    International Nuclear Information System (INIS)

    Winterberg, F.

    1984-01-01

    It is shown, that the introduction of a fundamental length constant into the operator representation of the quantum mechanical commutation relations, as suggested by Bagge, leads to a nonlinear generalization of the Lorentz transformations. The theory requires the introduction of a substratum (ether) and which can be identified as the zero point vacuum energy. At very high energies a non-Lorentz invariant behaviour for the cross sections between elementary particles is predicted. Using the Einstein clock synchronisation definition, the velocity of light is also constant and equal to c in the new theory, but the zero point vacuum energy becomes finite, as are all other quantities which are divergent in Lorentz invariant quantum field theories. In the limiting case where the length constant is set equal to zero, the zero point vacuum energy diverges and special relativity is recovered. (orig.) [de

  16. Highly task-related diversity vs. less task-related diversity among university staff

    DEFF Research Database (Denmark)

    Lauring, Jakob; Selmer, Jan

    2013-01-01

    from 489 university staff members showed that age diversity and cultural diversity, representing highly task-related diversity, were positively associated with most of the variables depicting group cohesiveness. On the other hand, gender diversity, illustrating less task-related diversity, seemed......As only very few large-scale studies have investigated multi-cultural university staff and as none of these studies have dealt with diversity and group processes, this survey was directed toward staffs in 16 science departments from three large universities in Denmark. Results based on the response...

  17. Sports-Related Emergency Preparedness in Oregon High Schools.

    Science.gov (United States)

    Johnson, Samuel T; Norcross, Marc F; Bovbjerg, Viktor E; Hoffman, Mark A; Chang, Eunwook; Koester, Michael C

    Best practice recommendations for sports-related emergency preparation include implementation of venue-specific emergency action plans (EAPs), access to early defibrillation, and first responders-specifically coaches-trained in cardiopulmonary resuscitation and automated external defibrillator (AED) use. The objective was to determine whether high schools had implemented these 3 recommendations and whether schools with a certified athletic trainer (AT) were more likely to have done so. Schools with an AT were more likely to have implemented the recommendations. Cross-sectional study. Level 4. All Oregon School Activities Association member school athletic directors were invited to complete a survey on sports-related emergency preparedness and AT availability at their school. Chi-square and Fisher exact tests were used to analyze the associations between emergency preparedness and AT availability. In total, 108 respondents (37% response rate) completed the survey. Exactly half reported having an AT available. Only 11% (95% CI, 6%-19%) of the schools had implemented all 3 recommendations, 29% (95% CI, 21%-39%) had implemented 2, 32% (95% CI, 24%-42%) had implemented 1, and 27% (95% CI, 19%-36%) had not implemented any of the recommendations. AT availability was associated with implementation of the recommendations (χ 2 = 10.3, P = 0.02), and the proportion of schools with ATs increased with the number of recommendations implemented (χ 2 = 9.3, P Schools with an AT were more likely to implement venue-specific EAPs (52% vs 24%, P schools were inadequately prepared for sports-related emergencies. Schools with an AT were more likely to implement some, but not all, of the recommendations. Policy changes may be needed to improve implementation. Most Oregon high schools need to do more to prepare for sports-related emergencies. The results provide evidence for sports medicine professionals and administrators to inform policy changes that ensure the safety of athletes.

  18. Physical principles demonstrate that the biceps femoris muscle relative to the other hamstring muscles exerts the most force: implications for hamstring muscle strain injuries.

    Science.gov (United States)

    Dolman, Bronwyn; Verrall, Geoffrey; Reid, Iain

    2014-07-01

    Of the hamstring muscle group the biceps femoris muscle is the most commonly injured muscle in sports requiring interval sprinting. The reason for this observation is unknown. The objective of this study was to calculate the forces of all three hamstring muscles, relative to each other, during a lengthening contraction to assess for any differences that may help explain the biceps femoris predilection for injury during interval sprinting. To calculate the displacement of each individual hamstring muscle previously performed studies on cadaveric anatomical data and hamstring kinematics during sprinting were used. From these displacement calculations for each individual hamstring muscle physical principles were then used to deduce the proportion of force exerted by each individual hamstring muscle during a lengthening muscle contraction. These deductions demonstrate that the biceps femoris muscle is required to exert proportionally more force in a lengthening muscle contraction relative to the semimembranosus and semitendinosus muscles primarily as a consequence of having to lengthen over a greater distance within the same time frame. It is hypothesized that this property maybe a factor in the known observation of the increased susceptibility of the biceps femoris muscle to injury during repeated sprints where recurrent higher force is required.

  19. High-Current Cold Cathode Employing Diamond and Related Materials

    Energy Technology Data Exchange (ETDEWEB)

    Hirshfield, Jay L. [Omega-P, Inc., New Haven, CT (United States)

    2014-10-22

    The essence of this project was for diamond films to be deposited on cold cathodes to improve their emission properties. Films with varying morphology, composition, and size of the crystals were deposited and the emission properties of the cathodes that utilize such films were studied. The prototype cathodes fabricated by the methods developed during Phase I were tested and evaluated in an actual high-power RF device during Phase II. These high-power tests used the novel active RF pulse compression system and the X-band magnicon test facility at US Naval Research Laboratory. In earlier tests, plasma switches were employed, while tests under this project utilized electron-beam switching. The intense electron beams required in the switches were supplied from cold cathodes embodying diamond films with varying morphology, including uncoated molybdenum cathodes in the preliminary tests. Tests with uncoated molybdenum cathodes produced compressed X-band RF pulses with a peak power of 91 MW, and a maximum power gain of 16.5:1. Tests were also carried out with switches employing diamond coated cathodes. The pulse compressor was based on use of switches employing electron beam triggering to effect mode conversion. In experimental tests, the compressor produced 165 MW in a ~ 20 ns pulse at ~18× power gain and ~ 140 MW at ~ 16× power gain in a 16 ns pulse with a ~ 7 ns flat-top. In these tests, molybdenum blade cathodes with thin diamond coatings demonstrated good reproducible emission uniformity with a 100 kV, 100 ns high voltage pulse. The new compressor does not have the limitations of earlier types of active pulse compressors and can operate at significantly higher electric fields without breakdown.

  20. Digital Libraries that Demonstrate High Levels of Mutual Complementarity in Collection-level Metadata Give a Richer Representation of their Content and Improve Subject Access for Users

    Directory of Open Access Journals (Sweden)

    Aoife Lawton

    2014-12-01

    Full Text Available A Review of: Zavalina, O. L. (2013. Complementarity in subject metadata in large-scale digital libraries: A comparative analysis. Cataloging & Classification Quarterly, 52(1, 77-89. http://dx.doi.org/10.1080/01639374.2013.848316 Abstract Objective – To determine how well digital library content is represented through free-text and subject headings. Specifically to examine whether a combination of free-text description data and controlled vocabulary is more comprehensive than free-text description data alone in describing digital collections. Design – Qualitative content analysis and complementarity comparison. Setting – Three large scale cultural heritage digital libraries: one in Europe and two in the United States of America. Methods – The researcher retrieved XML files of complete metadata records for two of the digital libraries, while the third library openly exposed its full metadata. The systematic samples obtained for all three libraries enabled qualitative content analysis to uncover how metadata values relate to each other at the collection level. The researcher retrieved 99 collection-level metadata records in total for analysis. The breakdown was 39, 33, and 27 records per digital library. When comparing metadata in the free-text Description metadata element with data in four controlled vocabulary elements, Subject, Geographic Coverage, Temporal Coverage and Object Type, the researcher observed three types of complementarity: one-way, two-way and multiple-complementarity. The author refers to complementarity as “describing a collection’s subject matter with mutually complementary data values in controlled vocabulary and free-text subject metadata elements” (Zavalina, 2013, p. 77. For example, within a Temporal Coverage metadata element the term “19th century” would complement a Description metadata element “1850–1899” in the same record. Main Results – The researcher found a high level of one

  1. Molecular cloning, expression and immunological characterisation of Lol p 5C, a novel allergen isoform of rye grass pollen demonstrating high IgE reactivity.

    Science.gov (United States)

    Suphioglu, C; Mawdsley, D; Schäppi, G; Gruehn, S; de Leon, M; Rolland, J M; O'Hehir, R E

    1999-12-03

    A novel isoform of a major rye grass pollen allergen Lol p 5 was isolated from a cDNA expression library. The new isoform, Lol p 5C, shares 95% amino acid sequence identity with Lol p 5A. Both isoforms demonstrated shared antigenic activity but different allergenic activities. Recombinant Lol p 5C demonstrated 100% IgE reactivity in 22 rye grass pollen sensitive patients. In comparison, recombinant Lol p 5A showed IgE reactivity in less than 64% of the patients. Therefore, Lol p 5C represents a novel and highly IgE-reactive isoform allergen of rye grass pollen.

  2. High relative frequency of thyroid papillary carcinoma in northern Portugal.

    Science.gov (United States)

    Sambade, M C; Gonçalves, V S; Dias, M; Sobrinho-Simões, M A

    1983-05-01

    Two hundred and twelve papillary and 40 follicular carcinomas were found in 3002 thyroid glands examined from 1931 to 1975 in four Laboratories of Pathology that fairly cover northern Portugal. There was a striking preponderance of women both in papillary (female:male = 6.9:1) and follicular carcinoma (5.7:1). Sex-specific frequency of malignancy was significantly greater in men (13.3%) than in women (8.8%). The overall papillary/follicular ratio was 5.3:1 and did not significantly change throughout the study period. Papillary/follicular ratio was not significantly greater in litoral (5.5:1) than in regions with a low iodine intake and a relatively high prevalence of goiter (3.5:1). It is advanced that this high relative frequency of papillary carcinoma in northern Portugal, even in goiter areas, may reflect the existence of a racial factor since there is not enough evidence to support the influence of dietary iodine, previous irradiation and concurrent thyroiditis.

  3. Some aspects related to the high performance in gamma spectrometry

    International Nuclear Information System (INIS)

    Vieru, Gheorghe; Mihaiu, Ramona; Nistor, Viorica

    2010-01-01

    Full text: Gamma spectroscopy is the science (or art) of identification and/or quantification of radionuclides through gamma-ray energy spectrum analysis. It is a recognized technique, well illustrated by the following examples: environmental radioactivity monitoring, health physics personnel monitoring, reactor corrosion monitoring, nuclear materials safeguards and homeland security, as well as nuclear forensics, materials testing, nuclear medicine and radiopharmaceuticals, and industrial process monitoring. Within the Reliability and Testing Laboratory of INR Pitesti there is now available such a detector of high performance that includes all aspects related to cooling, signal processing (with a high resolution) and the dedicated software applications. At the present time, taking into account the 'nuclear renaissance' the new experimental testing laboratories require complete set-up rather than laboratories having a mixture of the old equipment. The paper presents the mechanically cooled HPGe spectrometers with an undergoing rapid evolution, which eliminate traditional intensive liquid nitrogen management. Also, there are described the digital signal processing virtually by eliminating system drift, and, at the same time, requiring recalibrations much less frequently. Another important aspect presented is related to the software applications, which cover a broad spectrum of nuclear measurement techniques. (authors)

  4. Challenging demonstrations in the physics classroom

    International Nuclear Information System (INIS)

    Raz, E.

    2004-01-01

    Full Text: We consider the role of classroom demonstrations in improving students understanding of physics lectures and suggest criteria to decide whether a given demonstration will be pedagogically useful. In the light of these considerations, we performed two series of related experiments before groups of high-school students. We shall perform one of them with active participation from the audience. We shall also show some challenging demonstrations performed in the final stages of the Israeli Physics Olympiad for high-school students

  5. Strand Invasion Based Amplification (SIBA®): a novel isothermal DNA amplification technology demonstrating high specificity and sensitivity for a single molecule of target analyte.

    Science.gov (United States)

    Hoser, Mark J; Mansukoski, Hannu K; Morrical, Scott W; Eboigbodin, Kevin E

    2014-01-01

    Isothermal nucleic acid amplification technologies offer significant advantages over polymerase chain reaction (PCR) in that they do not require thermal cycling or sophisticated laboratory equipment. However, non-target-dependent amplification has limited the sensitivity of isothermal technologies and complex probes are usually required to distinguish between non-specific and target-dependent amplification. Here, we report a novel isothermal nucleic acid amplification technology, Strand Invasion Based Amplification (SIBA). SIBA technology is resistant to non-specific amplification, is able to detect a single molecule of target analyte, and does not require target-specific probes. The technology relies on the recombinase-dependent insertion of an invasion oligonucleotide (IO) into the double-stranded target nucleic acid. The duplex regions peripheral to the IO insertion site dissociate, thereby enabling target-specific primers to bind. A polymerase then extends the primers onto the target nucleic acid leading to exponential amplification of the target. The primers are not substrates for the recombinase and are, therefore unable to extend the target template in the absence of the IO. The inclusion of 2'-O-methyl RNA to the IO ensures that it is not extendible and that it does not take part in the extension of the target template. These characteristics ensure that the technology is resistant to non-specific amplification since primer dimers or mis-priming are unable to exponentially amplify. Consequently, SIBA is highly specific and able to distinguish closely-related species with single molecule sensitivity in the absence of complex probes or sophisticated laboratory equipment. Here, we describe this technology in detail and demonstrate its use for the detection of Salmonella.

  6. Strand Invasion Based Amplification (SIBA®: a novel isothermal DNA amplification technology demonstrating high specificity and sensitivity for a single molecule of target analyte.

    Directory of Open Access Journals (Sweden)

    Mark J Hoser

    Full Text Available Isothermal nucleic acid amplification technologies offer significant advantages over polymerase chain reaction (PCR in that they do not require thermal cycling or sophisticated laboratory equipment. However, non-target-dependent amplification has limited the sensitivity of isothermal technologies and complex probes are usually required to distinguish between non-specific and target-dependent amplification. Here, we report a novel isothermal nucleic acid amplification technology, Strand Invasion Based Amplification (SIBA. SIBA technology is resistant to non-specific amplification, is able to detect a single molecule of target analyte, and does not require target-specific probes. The technology relies on the recombinase-dependent insertion of an invasion oligonucleotide (IO into the double-stranded target nucleic acid. The duplex regions peripheral to the IO insertion site dissociate, thereby enabling target-specific primers to bind. A polymerase then extends the primers onto the target nucleic acid leading to exponential amplification of the target. The primers are not substrates for the recombinase and are, therefore unable to extend the target template in the absence of the IO. The inclusion of 2'-O-methyl RNA to the IO ensures that it is not extendible and that it does not take part in the extension of the target template. These characteristics ensure that the technology is resistant to non-specific amplification since primer dimers or mis-priming are unable to exponentially amplify. Consequently, SIBA is highly specific and able to distinguish closely-related species with single molecule sensitivity in the absence of complex probes or sophisticated laboratory equipment. Here, we describe this technology in detail and demonstrate its use for the detection of Salmonella.

  7. Thermodynamic relations in high temperature and high pressure physics of solids

    International Nuclear Information System (INIS)

    Kumar, Munish

    1998-01-01

    Various possible simple relations based on the exact and approximate thermodynamic relations are derived. These relations can be used to investigate the variation of unit cell volume under the effect of pressure and temperature. Thermal expansivity and compressibility can be investigated directly at any pressure or temperature, or through the knowledge of equation of state (EOS). A relation to determine Anderson-Grueneisen parameter δ T under the effect of pressure is predicted. It is discussed that δ T is independent of pressure and thus Murnaghan equation of state works well in low pressure ranges, while the variation of δ T under high pressure should be taken into account. The product of coefficient of volume thermal expansion and bulk modulus remains constant, is correct at high pressure, provided that the pressure dependence of δ T is considered. (author)

  8. Demonstration of pyropartitioning process by using genuine high-level liquid waste. Reductive-extraction of actinide elements from chlorination product

    International Nuclear Information System (INIS)

    Uozumi, Koichi; Iizuka, Masatoshi; Kurata, Masaki; Ougier, Michel; Malmbeck, Rikard; Winckel, Stefaan van

    2009-01-01

    The pyropartitioning process separates the minor actinide elements (MAs) together with uranium and plutonium from the high-level liquid waste generated at the Purex reprocessing of spent LWR fuel and introduces them to metallic fuel cycle. For the demonstration of this technology, a series experiment using 520g of genuine high-level liquid waste was started and the conversion of actinide elements to their chlorides was already demonstrated by denitration and chlorination. In the present study, a reductive extraction experiment in molten salt/liquid cadmium system to recover actinide elements from the chlorination product of the genuine high-level liquid waste was performed. The results of the experiment are as following; 1) By the addition of the cadmium-lithium alloy reductant, almost all of plutonium and MAs in the initial high-level liquid waste were recovered in the cadmium phase. It means no mass loss during denitration, chlorination, and reductive-extraction. 2) The separation factor values of plutonium, MAs, and rare-earth fission product elements versus uranium agreed with the literature values. Therefore, actinide elements will be separated from fission product elements in the actual system. Hence, the pyropartitioning process was successfully demonstrated. (author)

  9. Main outcomes from in situ thermo-hydro-mechanical experiments programme to demonstrate feasibility of radioactive high-level waste disposal in the Callovo-Oxfordian claystone

    Directory of Open Access Journals (Sweden)

    G. Armand

    2017-06-01

    Full Text Available In the context of radioactive waste disposal, an underground research laboratory (URL is a facility in which experiments are conducted to demonstrate the feasibility of constructing and operating a radioactive waste disposal facility within a geological formation. The Meuse/Haute-Marne URL is a site-specific facility planned to study the feasibility of a radioactive waste disposal in the Callovo-Oxfordian (COx claystone. The thermo-hydro-mechanical (THM behaviour of the host rock is significant for the design of the underground nuclear waste disposal facility and for its long-term safety. The French National Radioactive Waste Management Agency (Andra has begun a research programme aiming to demonstrate the relevancy of the French high-level waste (HLW concept. This paper presents the programme implemented from small-scale (small diameter boreholes to full-scale demonstration experiments to study the THM effects of the thermal transient on the COx claystone and the strategy implemented in this new programme to demonstrate and optimise current disposal facility components for HLW. It shows that the French high-level waste concept is feasible and working in the COx claystone. It also exhibits that, as for other plastic clay or claystone, heating-induced pore pressure increases and that the THM behaviour is anisotropic.

  10. Mice with diet-induced obesity demonstrate a relative prothrombotic factor profile and a thicker aorta with reduced ex-vivo function.

    Science.gov (United States)

    Uner, Aykut G; Unsal, Cengiz; Unsal, Humeyra; Erdogan, Mumin A; Koc, Ece; Ekici, Mehmet; Avci, Hamdi; Balkaya, Muharrem; Belge, Ferda; Tarin, Lokman

    2018-04-01

    : Classical risk factors such as cholesterol and lipoproteins are currently not sufficient to explain all physiopathological processes of obesity-related vascular dysfunction as well as atherosclerosis and arteriosclerosis. Therefore, the discovery of potential markers involved in vascular dysfunction in the obese state is still needed. Disturbances in hemostatic factors may be involved in the developmental processes associated with obesity-related cardiovascular disorders. We hypothesized that alterations of several hemostatic factors in the obese state could correlate with the function and morphology of the aorta and it could play an important role in the development of vascular dysfunction. To test this, we fed mice with a high-fat diet for 18 weeks and investigated the relationships between selected hemostatic factors (in either plasma or in the liver), metabolic hormones and morphology, and ex-vivo function of the aorta. Here, we show that 18-week exposure to a high-fat diet results in a higher plasma fibrinogen and prolonged prothrombin time in diet-induced obese mice compared to the controls. In addition, liver levels or activities of FII, FX, activated protein C, AT-III, and protein S are significantly different in diet-induced obese mice as compared to the controls. Curiously, FII, FVIII, FX, activated protein C, PTT, and protein S are correlated with both the aorta histology (aortic thickness and diameter) and ex-vivo aortic function. Notably, ex-vivo studies revealed that diet-induced obese mice show a marked attenuation in the functions of the aorta. Taken together, aforementioned hemostatic factors may be considered as critical markers for obesity-related vascular dysfunction and they could play important roles in diagnosing of the dysfunction.

  11. High-Throughput Screening and Hit Validation of Extracellular-Related Kinase 5 (ERK5) Inhibitors.

    Science.gov (United States)

    Myers, Stephanie M; Bawn, Ruth H; Bisset, Louise C; Blackburn, Timothy J; Cottyn, Betty; Molyneux, Lauren; Wong, Ai-Ching; Cano, Celine; Clegg, William; Harrington, Ross W; Leung, Hing; Rigoreau, Laurent; Vidot, Sandrine; Golding, Bernard T; Griffin, Roger J; Hammonds, Tim; Newell, David R; Hardcastle, Ian R

    2016-08-08

    The extracellular-related kinase 5 (ERK5) is a promising target for cancer therapy. A high-throughput screen was developed for ERK5, based on the IMAP FP progressive binding system, and used to identify hits from a library of 57 617 compounds. Four distinct chemical series were evident within the screening hits. Resynthesis and reassay of the hits demonstrated that one series did not return active compounds, whereas three series returned active hits. Structure-activity studies demonstrated that the 4-benzoylpyrrole-2-carboxamide pharmacophore had excellent potential for further development. The minimum kinase binding pharmacophore was identified, and key examples demonstrated good selectivity for ERK5 over p38α kinase.

  12. Crown traits of coniferous trees and their relation to shade tolerance can differ with leaf type: a biophysical demonstration using computed tomography scanning data.

    Science.gov (United States)

    Dutilleul, Pierre; Han, Liwen; Valladares, Fernando; Messier, Christian

    2015-01-01

    Plant light interception and shade tolerance are intrinsically related in that they involve structural, morphological and physiological adaptations to manage light capture for photosynthetic utilization, in order to sustain survival, development and reproduction. At the scale of small-size trees, crown traits related to structural geometry of branching pattern and space occupancy through phyllotaxis can be accurately evaluated in 3D, using computed tomography (CT) scanning data. We demonstrate this by scrutinizing the crowns of 15 potted miniature conifers of different species or varieties, classified in two groups based on leaf type (10 needlelike, 5 scalelike); we also test whether mean values of crown traits measured from CT scanning data and correlations with a shade tolerance index (STI) differ between groups. Seven crown traits, including fractal dimensions (FD1: smaller scales, FD2: larger scales) and leaf areas, were evaluated for all 15 miniature conifers; an average silhouette-to-total-area ratio was also calculated for each of the 10 needlelike-leaf conifers. Between-group differences in mean values are significant (P conifers with scalelike leaves, which had lower STI and higher FD1 on average in our study; the positive correlation between STI and ĀD is significant (P < 0.05) for the scalelike-leaf group, and very moderate for the needlelike-leaf one. A contrasting physical attachment of the leaves to branches may explain part of the between-group differences. Our findings open new avenues for the understanding of fundamental plant growth processes; the information gained could be included in a multi-scale approach to tree crown modeling.

  13. Conceptual design of high resolution and reliable density measurement system on helical reactor FFHR-d1 and demonstration on LHD

    International Nuclear Information System (INIS)

    Akiyama, T.; Yasuhara, R.; Isobe, M.; Sakamoto, R.; Goto, T.; Kawahata, K.; Sagara, A.; Nakayama, K.; Okajima, S.

    2014-10-01

    This paper describes a conceptual design of the density measurement system on the helical reactor FFHR-d1 based on its quantitative operation scenario. The density measurement is required to meet the reactor design, and to have a high density resolution of the order of 10 17 m -3 with a time resolution of 10 ms and high reliability (no fringe jump). “A dispersion interferometer” is designed and a prototype is tested and installed on LHD, which can realize a demo relevant density plasma. The prototype demonstrates the feasibility on a demo reactor. (author)

  14. IBM Demonstrates a General-Purpose, High-Performance, High-Availability Cloud-Hosted Data Distribution System With Live GOES-16 Weather Satellite Data

    Science.gov (United States)

    Snyder, P. L.; Brown, V. W.

    2017-12-01

    IBM has created a general purpose, data-agnostic solution that provides high performance, low data latency, high availability, scalability, and persistent access to the captured data, regardless of source or type. This capability is hosted on commercially available cloud environments and uses much faster, more efficient, reliable, and secure data transfer protocols than the more typically used FTP. The design incorporates completely redundant data paths at every level, including at the cloud data center level, in order to provide the highest assurance of data availability to the data consumers. IBM has been successful in building and testing a Proof of Concept instance on our IBM Cloud platform to receive and disseminate actual GOES-16 data as it is being downlinked. This solution leverages the inherent benefits of a cloud infrastructure configured and tuned for continuous, stable, high-speed data dissemination to data consumers worldwide at the downlink rate. It also is designed to ingest data from multiple simultaneous sources and disseminate data to multiple consumers. Nearly linear scalability is achieved by adding servers and storage.The IBM Proof of Concept system has been tested with our partners to achieve in excess of 5 Gigabits/second over public internet infrastructure. In tests with live GOES-16 data, the system routinely achieved 2.5 Gigabits/second pass-through to The Weather Company from the University of Wisconsin-Madison SSEC. Simulated data was also transferred from the Cooperative Institute for Climate and Satellites — North Carolina to The Weather Company, as well. The storage node allocated to our Proof of Concept system as tested was sized at 480 Terabytes of RAID protected disk as a worst case sizing to accommodate the data from four GOES-16 class satellites for 30 days in a circular buffer. This shows that an abundance of performance and capacity headroom exists in the IBM design that can be applied to additional missions.

  15. Fasciola hepatica demonstrates high levels of genetic diversity, a lack of population structure and high gene flow: possible implications for drug resistance.

    Science.gov (United States)

    Beesley, Nicola J; Williams, Diana J L; Paterson, Steve; Hodgkinson, Jane

    2017-01-01

    Fasciola hepatica, the liver fluke, is a trematode parasite of considerable economic importance to the livestock industry and is a re-emerging zoonosis that poses a risk to human health in F. hepatica-endemic areas worldwide. Drug resistance is a substantial threat to the current and future control of F. hepatica, yet little is known about how the biology of the parasite influences the development and spread of resistance. Given that F. hepatica can self-fertilise and therefore inbreed, there is the potential for greater population differentiation and an increased likelihood of recessive alleles, such as drug resistance genes, coming together. This could be compounded by clonal expansion within the snail intermediate host and aggregation of parasites of the same genotype on pasture. Alternatively, widespread movement of animals that typically occurs in the UK could promote high levels of gene flow and prevent population differentiation. We identified clonal parasites with identical multilocus genotypes in 61% of hosts. Despite this, 84% of 1579 adult parasites had unique multilocus genotypes, which supports high levels of genotypic diversity within F. hepatica populations. Our analyses indicate a selfing rate no greater than 2%, suggesting that this diversity is in part due to the propensity for F. hepatica to cross-fertilise. Finally, although we identified high genetic diversity within a given host, there was little evidence for differentiation between populations from different hosts, indicating a single panmictic population. This implies that, once those emerge, anthelmintic resistance genes have the potential to spread rapidly through liver fluke populations. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

  16. Gigashot Optical Laser Demonstrator

    Energy Technology Data Exchange (ETDEWEB)

    Deri, R. J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2015-10-13

    The Gigashot Optical Laser Demonstrator (GOLD) project has demonstrated a novel optical amplifier for high energy pulsed lasers operating at high repetition rates. The amplifier stores enough pump energy to support >10 J of laser output, and employs conduction cooling for thermal management to avoid the need for expensive and bulky high-pressure helium subsystems. A prototype amplifier was fabricated, pumped with diode light at 885 nm, and characterized. Experimental results show that the amplifier provides sufficient small-signal gain and sufficiently low wavefront and birefringence impairments to prove useful in laser systems, at repetition rates up to 60 Hz.

  17. High temperature electrochemistry related to light water reactor corrosion

    International Nuclear Information System (INIS)

    Nagy, Gabor; Kerner, Zsolt; Balog, Janos; Schiller, Robert

    2004-01-01

    The present work deals with corrosion problems related to conditions which prevail in a WWER primary circuit. We had a two-fold aim: (A) electrochemical methods were applied to characterise the hydrothermally produced oxides of the cladding material (Zr-1%Nb) of nuclear fuel elements used in Russian made power reactors of WWER type, and (B) a number of possible reference electrodes were investigated with a view to high temperature applications. (A) Test specimens made of the cladding material, Zr-1%Nb, were immersed into an autoclave, filled with an aqueous solution typical to a WWER primary circuit, and were treated for different periods of time up to 28 weeks. The electrode potentials were measured and electrochemical impedance spectra (EIS) were taken regularly both as a function of oxidation time and temperature. This rendered information on the overall kinetics of oxide growth. By combining in situ and ex situ impedance measurements, with a particular view of the temperature dependence of EIS, we concluded that the high frequency region of impedance spectra is relevant to the presence of oxide layer on the alloy. This part of the spectra was treated in terms of a parallel CPE||R ox equivalent circuit (CPE denoting constant phase element, R ox ohmic resistor). The CPE element was understood as a dispersive resistance in terms of the continuous time random walk theory by Scher and Lax. This enabled us to tell apart electrical conductance and oxide growth with a model of charge transfer and recombination within the oxide layer as rate determining steps. (B) Three types of reference electrodes were tested within the framework of the LIRES EU5 project: (i) external Ag/AgCl, (ii) Pt/Ir alloy and (iii) Pd(Pt) double polarised active electrode. The most stable of the electrodes was found to be the Pt/Ir one. The Ag/AgCl electrode showed good stability after an initial period of some days, while substantial drifts were found for the Pd(Pt) electrode. EIS spectra of the

  18. Crown traits of coniferous trees and their relation to shade tolerance can differ with leaf type: a biophysical demonstration using computed tomography scanning data

    Science.gov (United States)

    Dutilleul, Pierre; Han, Liwen; Valladares, Fernando; Messier, Christian

    2015-01-01

    Plant light interception and shade tolerance are intrinsically related in that they involve structural, morphological and physiological adaptations to manage light capture for photosynthetic utilization, in order to sustain survival, development and reproduction. At the scale of small-size trees, crown traits related to structural geometry of branching pattern and space occupancy through phyllotaxis can be accurately evaluated in 3D, using computed tomography (CT) scanning data. We demonstrate this by scrutinizing the crowns of 15 potted miniature conifers of different species or varieties, classified in two groups based on leaf type (10 needlelike, 5 scalelike); we also test whether mean values of crown traits measured from CT scanning data and correlations with a shade tolerance index (STI) differ between groups. Seven crown traits, including fractal dimensions (FD1: smaller scales, FD2: larger scales) and leaf areas, were evaluated for all 15 miniature conifers; an average silhouette-to-total-area ratio was also calculated for each of the 10 needlelike-leaf conifers. Between-group differences in mean values are significant (P < 0.05) for STI, FD1, FD2, and the average leaf area displayed (ĀD). Between-group differences in sign and strength of correlations are observed. For example, the correlation between STI and FD1 is negative and significant (P < 0.10) for the needlelike-leaf group, but is positive and significant (P < 0.05) for the miniature conifers with scalelike leaves, which had lower STI and higher FD1 on average in our study; the positive correlation between STI and ĀD is significant (P < 0.05) for the scalelike-leaf group, and very moderate for the needlelike-leaf one. A contrasting physical attachment of the leaves to branches may explain part of the between-group differences. Our findings open new avenues for the understanding of fundamental plant growth processes; the information gained could be included in a multi-scale approach to tree crown

  19. Crown traits of coniferous trees and their relation to shade tolerance can differ with leaf type: A biophysical demonstration using computed tomography scanning data

    Directory of Open Access Journals (Sweden)

    Pierre eDutilleul

    2015-03-01

    Full Text Available Plant light interception and shade tolerance are intrinsically related in that they involve structural, morphological and physiological adaptations to manage light capture for photosynthetic utilization, in order to sustain survival, development and reproduction. At the scale of small-size trees, crown traits related to structural geometry of branching pattern and space occupancy through phyllotaxis can be accurately evaluated in 3D, using computed tomography (CT scanning data. We demonstrate this by scrutinizing the crowns of 15 potted miniature conifers of different species or varieties, classified in two groups based on leaf type (10 needlelike, 5 scalelike; we also test whether mean values of crown traits measured from CT scanning data and correlations with a shade tolerance index (STI differ between groups. Seven crown traits, including fractal dimensions (FD1: smaller scales, FD2: larger scales and leaf areas, were evaluated for all 15 miniature conifers; an average silhouette-to-total-area ratio was also calculated for each of the 10 needlelike-leaf conifers. Between-group differences in mean values are significant (P < 0.05 for STI, FD1, FD2, and average leaf area displayed (A_D. Between-group differences in sign and strength of correlations are observed. For example, the correlation between STI and FD1 is negative and significant (P < 0.10 for the needlelike-leaf group, but is positive and significant (P < 0.05 for the miniature conifers with scalelike leaves, which had lower STI and higher FD1 on average in our study; the positive correlation between STI and A_D is significant (P < 0.05 for the scalelike-leaf group, and very moderate for the needlelike-leaf one. A contrasting physical attachment of leaves to branches may explain part of the between-group differences. Our findings open new avenues for the understanding of fundamental plant growth processes; the information gained could be included in a multi-scale approach to tree crown

  20. Testing Special Relativity at High Energies with Astrophysical Sources

    Science.gov (United States)

    Stecker, F. W.

    2007-01-01

    Since the group of Lorentz boosts is unbounded, there is a question as to whether Lorentz invariance (LI) holds to infinitely short distances. However, special and general relativity may break down at the Planck scale. Various quantum gravity scenarios such as loop quantum gravity, as well as some forms of string theory and extra dimension models may imply Lorentz violation (LV) at ultrahigh energies. The Gamma-Ray Large Area Space Telescope (GLAST), to be launched in mid-December, will measure the spectra of distant extragalactic sources of high energy gamma-rays, particularly active galactic nuclei and gamma-ray bursts. GLAST can look for energy-dependent gamma-ray propagation effects from such sources as a signal of Lorentz invariance violation. These sources may also exhibit the high energy cutoffs predicted to be the result of intergalactic annihilation interactions with low energy photons having a flux level as determined by various astronomical observations. With LV the threshold for such interactions can be significantly raised, changing the predicted absorption turnover in the observed spectrum of the sources. Stecker and Glashow have shown that the existence such absorption features in the spectra of extragalactic sources puts constraints on LV. Such constraints have important implications for some quantum gravity and large extra dimension models. Future spaceborne detectors dedicated to measuring gamma-ray polarization can look for birefringence effects as a possible signal of loop quantum gravity. A very small LV may also result in the modification or elimination of the GZK effect, thus modifying the spectrum of ultrahigh energy cosmic rays. This possibility can be explored with ground-based arrays such as Auger or with a space based detector system such as the proposed OWL satellite mission.

  1. Demonstration of a switchable damping system to allow low-noise operation of high-Q low-mass suspension systems

    Science.gov (United States)

    Hennig, Jan-Simon; Barr, Bryan W.; Bell, Angus S.; Cunningham, William; Danilishin, Stefan L.; Dupej, Peter; Gräf, Christian; Hough, James; Huttner, Sabina H.; Jones, Russell; Leavey, Sean S.; Pascucci, Daniela; Sinclair, Martin; Sorazu, Borja; Spencer, Andrew; Steinlechner, Sebastian; Strain, Kenneth A.; Wright, Jennifer; Zhang, Teng; Hild, Stefan

    2017-12-01

    Low-mass suspension systems with high-Q pendulum stages are used to enable quantum radiation pressure noise limited experiments. Utilizing multiple pendulum stages with vertical blade springs and materials with high-quality factors provides attenuation of seismic and thermal noise; however, damping of these high-Q pendulum systems in multiple degrees of freedom is essential for practical implementation. Viscous damping such as eddy-current damping can be employed, but it introduces displacement noise from force noise due to thermal fluctuations in the damping system. In this paper we demonstrate a passive damping system with adjustable damping strength as a solution for this problem that can be used for low-mass suspension systems without adding additional displacement noise in science mode. We show a reduction of the damping factor by a factor of 8 on a test suspension and provide a general optimization for this system.

  2. Demonstration of high-responsivity epitaxial β-Ga2O3/GaN metal–heterojunction-metal broadband UV-A/UV-C detector

    Science.gov (United States)

    Kalra, Anisha; Vura, Sandeep; Rathkanthiwar, Shashwat; Muralidharan, Rangarajan; Raghavan, Srinivasan; Nath, Digbijoy N.

    2018-06-01

    We demonstrate epitaxial β-Ga2O3/GaN-based vertical metal–heterojunction-metal (MHM) broadband UV-A/UV-C photodetectors with high responsivity (3.7 A/W) at 256 and 365 nm, UV-to-visible rejection >103, and a photo-to-dark current ratio of ∼100. A small (large) conduction (valence) band offset at the heterojunction of pulsed laser deposition (PLD)-grown β-Ga2O3 on metal organic chemical vapor deposition (MOCVD)-grown GaN-on-silicon with epitaxial registry, as confirmed by X-ray diffraction (XRD) azimuthal scanning, is exploited to realize detectors with an asymmetric photoresponse and is explained with one-dimensional (1D) band diagram simulations. The demonstrated novel vertical MHM detectors on silicon are fully scalable and promising for enabling focal plane arrays for broadband ultraviolet sensing.

  3. MO-FG-CAMPUS-IeP2-05: Feasibility Demonstration of High-Voltage Clinical CT and Impact On X-Ray Penetration Through Metal Objects

    International Nuclear Information System (INIS)

    Jin, Y; De Man, B; Robinson, V; Gjesteby, L; Wang, G; Verburg, J; Giantsoudi, D; Paganetti, H

    2016-01-01

    Purpose: To demonstrate the possibility and quantify the impact of operating a clinical CT scanner at exceptionally high x-ray tube voltage for better penetration through metal objects and facilitating metal artifact reduction. Methods: We categorize metal objects according to the data corruption severeness (level of distortion and complete photon starvation fraction). To demonstrate feasibility and investigate the impact of high voltage scanning we modified a commercial GE LightSpeed VCT scanner (generator and software) to enable CT scans with x-ray tube voltages as high as 175 kVp. A 20 cm diameter water phantom with two metal rods (10 mm stainless and 25 mm titanium) and a water phantom with realistic metal object (spine cage) were used to evaluate the data corruption and image artifacts in the absence of any algorithm correction. We also performed simulations to confirm our understanding of the transmitted photon levels through metal objects with different size and composition. Results: The reconstructed images at 175 kVp still have significant dark shading artifacts, as expected since no special scatter correction or beam hardening was performed but show substantially lower noise and photon starvation than at lower kVp due to better beam penetration. Analysis of the raw data shows that the photon starved data is reduced from over 4% at 140 kVp to below 0.2% at 175 kVp. The simulations indicate that for clinically relevant titanium and stainless objects a 175 kVp tube voltage effectively avoids photon starvation. Conclusion: The use of exceptionally high tube voltage on a clinical CT system is a practical and effective solution to avoid photon starvation caused by certain metal implants. Sparse and hybrid high-voltage protocols are being considered to maintain low patient dose. This opens the door to algorithmic physics-based corrections rather than treating the data as missing and relying on missing data algorithms. Some of the authors are employees of General

  4. MO-FG-CAMPUS-IeP2-05: Feasibility Demonstration of High-Voltage Clinical CT and Impact On X-Ray Penetration Through Metal Objects

    Energy Technology Data Exchange (ETDEWEB)

    Jin, Y; De Man, B [GE Global Research, Niskayuna, NY (United States); Robinson, V [GE, Global Research, Niskayuna, NY (United States); Gjesteby, L [Rensselaer Polytechnic Institute, Troy, NY (United States); Wang, G [Rensselaer Polytechnic Institute Troy, NY (United States); Verburg, J [Massachusetts, General Hospital, Boston, MA (United States); Giantsoudi, D; Paganetti, H [Massachusetts General Hospital, Boston, MA (United States)

    2016-06-15

    Purpose: To demonstrate the possibility and quantify the impact of operating a clinical CT scanner at exceptionally high x-ray tube voltage for better penetration through metal objects and facilitating metal artifact reduction. Methods: We categorize metal objects according to the data corruption severeness (level of distortion and complete photon starvation fraction). To demonstrate feasibility and investigate the impact of high voltage scanning we modified a commercial GE LightSpeed VCT scanner (generator and software) to enable CT scans with x-ray tube voltages as high as 175 kVp. A 20 cm diameter water phantom with two metal rods (10 mm stainless and 25 mm titanium) and a water phantom with realistic metal object (spine cage) were used to evaluate the data corruption and image artifacts in the absence of any algorithm correction. We also performed simulations to confirm our understanding of the transmitted photon levels through metal objects with different size and composition. Results: The reconstructed images at 175 kVp still have significant dark shading artifacts, as expected since no special scatter correction or beam hardening was performed but show substantially lower noise and photon starvation than at lower kVp due to better beam penetration. Analysis of the raw data shows that the photon starved data is reduced from over 4% at 140 kVp to below 0.2% at 175 kVp. The simulations indicate that for clinically relevant titanium and stainless objects a 175 kVp tube voltage effectively avoids photon starvation. Conclusion: The use of exceptionally high tube voltage on a clinical CT system is a practical and effective solution to avoid photon starvation caused by certain metal implants. Sparse and hybrid high-voltage protocols are being considered to maintain low patient dose. This opens the door to algorithmic physics-based corrections rather than treating the data as missing and relying on missing data algorithms. Some of the authors are employees of General

  5. Relative Match Intensities at High Altitude in Highly-Trained Young Soccer Players (ISA3600).

    Science.gov (United States)

    Buchheit, Martin; Hammond, Kristal; Bourdon, Pitre C; Simpson, Ben M; Garvican-Lewis, Laura A; Schmidt, Walter F; Gore, Christopher J; Aughey, Robert J

    2015-03-01

    To compare relative match intensities of sea-level versus high-altitude native soccer players during a 2-week camp at 3600 m, data from 7 sea-level (Australian U17 National team, AUS) and 6 high-altitude (a Bolivian U18 team, BOL) native soccer players were analysed. Two matches were played at sea-level and three at 3600 m on Days 1, 6 and 13. The Yo-Yo Intermittent recovery test (vYo-YoIR1) was performed at sea-level, and on Days 3 and 10. Match activity profiles were measured via 10-Hz GPS. Distance covered >14.4 km.h(-1) (D>14.4 km·h(-1)) and >80% of vYo-YoIR1 (D>80%vYo-YoIR1) were examined. Upon arrival at altitude, there was a greater decrement in vYo-YoIR1 (Cohen's d +1.0, 90%CL ± 0.8) and D>14.4 km·h(-1) (+0.5 ± 0.8) in AUS. D>14.4 km.h(-1) was similarly reduced relative to vYo-YoIR1 in both groups, so that D>80%vYo-YoIR1 remained similarly unchanged (-0.1 ± 0.8). Throughout the altitude sojourn, vYo-YoIR1 and D>14.4 km·h(-1) increased in parallel in AUS, so that D>80%vYo-YoIR1 remained stable in AUS (+6.0%/match, 90%CL ± 6.7); conversely D>80%vYo-YoIR1 decreased largely in BOL (-12.2%/match ± 6.2). In sea-level natives competing at high-altitude, changes in match running performance likely follow those in high-intensity running performance. Bolivian data confirm that increases in 'fitness' do not necessarily translate into greater match running performance, but rather in reduced relative exercise intensity. Key pointsWhen playing at high-altitude, players may alter their activities during matches in relation to their transient maximal physical capacities, possibly to maintain a 'tolerable' relative exercise intensity.While there is no doubt that running performance per se in not the main determinant of match outcomes (Carling, 2013), fitness levels influence relative match intensity (Buchheit et al., 2012, Mendez-Villanueva et al., 2013), which in-turn may impact on decision making and skill performance (Rampinini et al., 2008).In the context of

  6. 1H High Resolution Magic-Angle Coil Spinning (HR-MACS µNMR Metabolic Profiling of whole Saccharomyces cervisiae cells: A Demonstrative Study

    Directory of Open Access Journals (Sweden)

    Alan eWong

    2014-06-01

    Full Text Available The low sensitivity of Nuclear Magnetic Resonance (NMR is its prime shortcoming compared to other analytical methods for metabolomic studies. It relies on large sample volume (30–50 µl for HR-MAS for rich metabolic profiling, hindering high-throughput screening especially when the sample requires a labor-intensive preparation or is a sacred specimen. This is indeed the case for some living organisms. This study evaluates a 1H HR-MAS approach for metabolic profiling of small volume (250 nl whole bacterial cells, Saccharomyces cervisiae, using an emerging micro-NMR technology: high-resolution magic-angle coil spinning (HR-MACS. As a demonstrative study for whole cells, we perform two independent metabolomics studies identifying the significant metabolites associated with osmotic stress and aging.

  7. Cultivar Differences in Plant Transpiration Rate at High Relative Air Humidity Are Not Related to Genotypic Variation in Stomatal Responsiveness

    DEFF Research Database (Denmark)

    Gebraegziabher, Habtamu Giday; Kjær, Katrine Heinsvig; Ottosen, Carl-Otto

    2015-01-01

    Plants grown at high relative air humidity (RH) often show disturbed water relations due to less responsive stomata. The attenuation of stomatal responsiveness as a result of high RH during leaf expansion depends on the cultivar. We hypothesized that tolerant cultivars to high RH experience a low...

  8. Demonstration of high mobility and quantum transport in modulation-doped β-(AlxGa1-x)2O3/Ga2O3 heterostructures

    Science.gov (United States)

    Zhang, Yuewei; Neal, Adam; Xia, Zhanbo; Joishi, Chandan; Johnson, Jared M.; Zheng, Yuanhua; Bajaj, Sanyam; Brenner, Mark; Dorsey, Donald; Chabak, Kelson; Jessen, Gregg; Hwang, Jinwoo; Mou, Shin; Heremans, Joseph P.; Rajan, Siddharth

    2018-04-01

    In this work, we demonstrate a high mobility two-dimensional electron gas (2DEG) formed at the β-(AlxGa1-x)2O3/Ga2O3 interface through modulation doping. Shubnikov-de Haas (SdH) oscillations were observed in the modulation-doped β-(AlxGa1-x)2O3/Ga2O3 structure, indicating a high-quality electron channel formed at the heterojunction interface. The formation of the 2DEG channel was further confirmed by the weak temperature dependence of the carrier density, and the peak low temperature mobility was found to be 2790 cm2/Vs, which is significantly higher than that achieved in bulk-doped Beta-phase Gallium Oxide (β-Ga2O3). The observed SdH oscillations allowed for the extraction of the electron effective mass in the (010) plane to be 0.313 ± 0.015 m0 and the quantum scattering time to be 0.33 ps at 3.5 K. The demonstrated modulation-doped β-(AlxGa1-x)2O3/Ga2O3 structure lays the foundation for future exploration of quantum physical phenomena and semiconductor device technologies based on the β-Ga2O3 material system.

  9. A high pressure x-ray photoelectron spectroscopy experimental method for characterization of solid-liquid interfaces demonstrated with a Li-ion battery system

    Energy Technology Data Exchange (ETDEWEB)

    Maibach, Julia; Xu, Chao; Gustafsson, Torbjörn; Edström, Kristina [Department of Chemistry–Ångström Laboratory, Uppsala University, Box 538, SE-751 21 Uppsala (Sweden); Eriksson, Susanna K. [Department of Chemistry–Ångström Laboratory, Uppsala University, Box 523, SE-751 20 Uppsala (Sweden); Åhlund, John [VG Scienta AB, Box 15120, SE-750 15 Uppsala (Sweden); Siegbahn, Hans; Rensmo, Håkan; Hahlin, Maria, E-mail: maria.hahlin@physics.uu.se [Department of Physics and Astronomy, Uppsala University, Box 516, SE-751 20 Uppsala (Sweden)

    2015-04-15

    We report a methodology for a direct investigation of the solid/liquid interface using high pressure x-ray photoelectron spectroscopy (HPXPS). The technique was demonstrated with an electrochemical system represented by a Li-ion battery using a silicon electrode and a liquid electrolyte of LiClO{sub 4} in propylene carbonate (PC) cycled versus metallic lithium. For the first time the presence of a liquid electrolyte was realized using a transfer procedure where the sample was introduced into a 2 mbar N{sub 2} environment in the analysis chamber without an intermediate ultrahigh vacuum (UHV) step in the load lock. The procedure was characterized in detail concerning lateral drop gradients as well as stability of measurement conditions over time. The X-ray photoelectron spectroscopy (XPS) measurements demonstrate that the solid substrate and the liquid electrolyte can be observed simultaneously. The results show that the solid electrolyte interphase (SEI) composition for the wet electrode is stable within the probing time and generally agrees well with traditional UHV studies. Since the methodology can easily be adjusted to various high pressure photoelectron spectroscopy systems, extending the approach towards operando solid/liquid interface studies using liquid electrolytes seems now feasible.

  10. Inseparable Phone Books Demonstration

    Science.gov (United States)

    Balta, Nuri; Çetin, Ali

    2017-01-01

    This study is aimed at first introducing a well-known discrepant event; inseparable phone books and second, turning it into an experiment for high school or middle school students. This discrepant event could be used especially to indicate how friction force can be effective in producing an unexpected result. Demonstration, discussion, explanation…

  11. Demonstration of Selective Catalytic Reduction Technology to Control Nitrogen Oxide Emissions From High-Sulfur, Coal-Fired Boilers: A DOE Assessment

    International Nuclear Information System (INIS)

    Federal Energy Technology Center

    1999-01-01

    The goal of the U.S. Department of Energy (DOE) Clean Coal Technology (CCT) program is to furnish the energy marketplace with a number of advanced, more efficient, and environmentally responsible coal utilization technologies through demonstration projects. These projects seek to establish the commercial feasibility of the most promising advanced coal technologies that have developed beyond the proof-of-concept stage. This document serves as a DOE post-project assessment of a project selected in CCT Round 2. The project is described in the report ''Demonstration of Selective Catalytic Reduction (SCR) Technology for the Control of Nitrogen Oxide (NO(sub x)) Emissions from High-Sulfur, Coal-Fired Boilers'' (Southern Company Services 1990). In June 1990, Southern Company Services (Southern) entered into a cooperative agreement to conduct the study. Southern was a cofunder and served as the host at Gulf Power Company's Plant Crist. Other participants and cofunders were EPRI (formerly the Electric Power Research Institute) and Ontario Hydro. DOE provided 40 percent of the total project cost of$23 million. The long-term operation phase of the demonstration was started in July 1993 and was completed in July 1995. This independent evaluation is based primarily on information from Southern's Final Report (Southern Company Services 1996). The SCR process consists of injecting ammonia (NH(sub 3)) into boiler flue gas and passing the 3 flue gas through a catalyst bed where the NO(sub x) and NH(sub 3) react to form nitrogen and water vapor. The objectives of the demonstration project were to investigate: Performance of a wide variety of SCR catalyst compositions, geometries, and manufacturing methods at typical U.S. high-sulfur coal-fired utility operating conditions; Catalyst resistance to poisoning by trace metal species present in U.S. coals but not present, or present at much lower concentrations, in fuels from other countries; and Effects on the balance-of-plant equipment

  12. Coaching and Demonstration of Evidence-Based Book-Reading Practices: Effects on Head Start Teachers' Literacy-Related Behaviors and Classroom Environment

    Science.gov (United States)

    Gettinger, Maribeth; Stoiber, Karen C.

    2016-01-01

    This study examined the effects of coaching with versus without demonstrations of evidence-based book-reading practices on teachers' use of strategies during independent book-reading periods. A total of 22 Head Start teachers were randomly assigned to one of two cohorts. One cohort (n = 12) participated in biweekly coaching sessions that included…

  13. Fears and Related Anxieties in Chinese High School Students

    Science.gov (United States)

    Li, Huijun; Prevatt, Frances

    2008-01-01

    Chinese students from different high school settings face unique academic and emotional challenges. They are in a very vulnerable position due to high parent and teacher expectations and pressure to succeed in college entrance examinations and honour the family and the school. They are also vulnerable due to possible inappropriate parenting…

  14. Epidemiology of soccer-related injuries among male high school ...

    African Journals Online (AJOL)

    Soccer in Rwandan high schools can expose players to the risk of injury warranting prevention programmes. The aim of this study was to determine the type, causes, severity and management of injuries among high school soccer players in Rwanda, in order to obtain baseline data for injury prevention programmes.

  15. Demonstration of InAlN/AlGaN high electron mobility transistors with an enhanced breakdown voltage by pulsed metal organic chemical vapor deposition

    Energy Technology Data Exchange (ETDEWEB)

    Xue, JunShuai, E-mail: junshuaixue@hotmail.com; Zhang, JinCheng; Hao, Yue [Key Laboratory of Wide Band Gap Semiconductor Materials and Devices, School of Microelectronics, Xidian University, Xi' an 710071 (China)

    2016-01-04

    In this work, InAlN/AlGaN heterostructures employing wider bandgap AlGaN instead of conventional GaN channel were grown on sapphire substrate by pulsed metal organic chemical vapor deposition, where the nominal Al composition in InAlN barrier and AlGaN channel were chosen to be 83% and 5%, respectively, to achieve close lattice-matched condition. An electron mobility of 511 cm{sup 2}/V s along with a sheet carrier density of 1.88 × 10{sup 13 }cm{sup −2} were revealed in the prepared heterostructures, both of which were lower compared with lattice-matched InAlN/GaN due to increased intrinsic alloy disorder scattering resulting from AlGaN channel and compressively piezoelectric polarization in barrier, respectively. While the high electron mobility transistor (HEMT) processed on these structures not only exhibited a sufficiently high drain output current density of 854 mA/mm but also demonstrated a significantly enhanced breakdown voltage of 87 V, which is twice higher than that of reported InAlN/GaN HEMT with the same device dimension, potential characteristics for high-voltage operation of GaN-based electronic devices.

  16. Arctic Solutions The Frozen (Thawing) Relations of the High North

    Energy Technology Data Exchange (ETDEWEB)

    Summers, Ch.

    2010-07-01

    It's cold, inhospitable and deadly. The image of the Arctic in years past is one of bewilderment, ignorance and awe. How the image of the Arctic has changed in recent years can be directly linked to our recognition that the Arctic has a great deal to offer in meeting the basic needs of future generations. Although we are still in awe of the Arctic's cruel beauty, new technologies are making it easier to explore the once unmanageable environment. The Arctic has moved into the mainstream with a host of suitors jockeying for position in the race to possess the Arctic and all that it contains. To highlight this increased interest, Russia's 'National Security Until 2020' initiative, has upgraded the High North to one of Russia's main priorities and identifies the Arctic as liable to produce military conflict in the future linked to competition for the Arctic's abundant raw materials.1 Even Canada, a peaceful and respectful country, has stepped outside the box of traditional Canadian rhetoric by giving Canada's Northern Strategy a tag line: 'Our North, our heritage, our future'. The Arctic is increasingly viewed as central to meeting the challenges of an ever changing world where climate change and economic benefit drive international agreements and policies. However Canada and Russia are not the only actors here. The other Arctic Five states: Denmark, Norway, and the United States of America all lay claims to some area or activity within the Arctic region. The Arctic is a unique part of this world, one that has been left largely untouched by human hands, and one that is on the brink of being changed forever. To fully understand Arctic issues, resource figures must be taken into account. Every nation involved in the Arctic debate has considered and based its policies on its set of numbers and resource estimates. A U.S. Geological Survey (USGS) in 2009 put Arctic resource figures in the range of thirty percent of the

  17. Arctic Solutions The Frozen (Thawing) Relations of the High North

    International Nuclear Information System (INIS)

    Summers, Ch.

    2010-01-01

    It's cold, inhospitable and deadly. The image of the Arctic in years past is one of bewilderment, ignorance and awe. How the image of the Arctic has changed in recent years can be directly linked to our recognition that the Arctic has a great deal to offer in meeting the basic needs of future generations. Although we are still in awe of the Arctic's cruel beauty, new technologies are making it easier to explore the once unmanageable environment. The Arctic has moved into the mainstream with a host of suitors jockeying for position in the race to possess the Arctic and all that it contains. To highlight this increased interest, Russia's 'National Security Until 2020' initiative, has upgraded the High North to one of Russia's main priorities and identifies the Arctic as liable to produce military conflict in the future linked to competition for the Arctic's abundant raw materials.1 Even Canada, a peaceful and respectful country, has stepped outside the box of traditional Canadian rhetoric by giving Canada's Northern Strategy a tag line: 'Our North, our heritage, our future'. The Arctic is increasingly viewed as central to meeting the challenges of an ever changing world where climate change and economic benefit drive international agreements and policies. However Canada and Russia are not the only actors here. The other Arctic Five states: Denmark, Norway, and the United States of America all lay claims to some area or activity within the Arctic region. The Arctic is a unique part of this world, one that has been left largely untouched by human hands, and one that is on the brink of being changed forever. To fully understand Arctic issues, resource figures must be taken into account. Every nation involved in the Arctic debate has considered and based its policies on its set of numbers and resource estimates. A U.S. Geological Survey (USGS) in 2009 put Arctic resource figures in the range of thirty percent of the remaining world reserves of natural gas and ten percent

  18. A mechanical model of stereocilia that demonstrates a shift in the high-sensitivity region due to the interplay of a negative stiffness and an adaptation mechanism

    International Nuclear Information System (INIS)

    Lee, Changwon; Park, Sukyung

    2012-01-01

    Stereocilia are the basic sensory units of nature's inertial sensors and are highly sensitive over broad dynamic ranges, which is a major challenge in the design of conventional engineering sensors. The high sensitivity that is maintained by stereocilia was hypothesized to exist due to a combination of adaptation and negative stiffness mechanisms, which shift the region of highest sensitivity toward the active operation range of the stereocilia bundle. To examine the adaptation hypothesis in terms of its potential applicability to future applications regarding the design of inertial sensors, we developed a mechanical mimicry of the interplay between negative stiffness and the adaptation of the stereocilia that produces spontaneous oscillation of the hair bundle. The mechanical model consists of an inverted pendulum and a fixed T-bar that mimic the interaction of two adjacent stereocilia. To focus on the interaction of one gating spring and the corresponding adaptation motor without the effect of coupling from the other gating springs attached to the neighboring stereocilia, we fixed one bar that contains the adaptation motor. To emulate the negative resistance of the tip-link due to the transient stiffness softening by the gating ion channel, a magnet pair was attached to the top of the inverted pendulum and the fixed T-bar. Readjustment of the tip-link tension by the ‘slipping down and climbing up’ motion of the adaptation molecular motors was demonstrated by the side-to-side movement of the magnet by a step motor. The negative stiffness region was observed near the equilibrium position and shifted with the activation of the adaptation motor. The temporal demonstration of the stiffness shift was measured as a spontaneous oscillation. The results showed that the interplay between the negative stiffness and the adaptation mechanism was mechanically produced by the combination of a repulsive force and its continuous readjustment and is better understood through a

  19. Highly transparent triboelectric nanogenerator for harvesting water-related energy reinforced by antireflection coating

    Science.gov (United States)

    Liang, Qijie; Yan, Xiaoqin; Gu, Yousong; Zhang, Kui; Liang, Mengyuan; Lu, Shengnan; Zheng, Xin; Zhang, Yue

    2015-03-01

    Water-related energy is an inexhaustible and renewable energy resource in our environment, which has huge amount of energy and is not largely dictated by daytime and sunlight. The transparent characteristic plays a key role in practical applications for some devices designed for harvesting water-related energy. In this paper, a highly transparent triboelectric nanogenerator (T-TENG) was designed to harvest the electrostatic energy from flowing water. The instantaneous output power density of the T-TENG is 11.56 mW/m2. Moreover, with the PTFE film acting as an antireflection coating, the maximum transmittance of the fabricated T-TENG is 87.4%, which is larger than that of individual glass substrate. The T-TENG can be integrated with silicon-based solar cell, building glass and car glass, which demonstrates its potential applications for harvesting waste water energy in our living environment and on smart home system and smart car system.

  20. Crown traits of coniferous trees and their relation to shade tolerance can differ with leaf type: a biophysical demonstration using computed tomography scanning data

    OpenAIRE

    Dutilleul, Pierre; Han, Liwen; Valladares, Fernando; Messier, Christian

    2015-01-01

    Plant light interception and shade tolerance are intrinsically related in that they involve structural, morphological and physiological adaptations to manage light capture for photosynthetic utilization, in order to sustain survival, development and reproduction. At the scale of small-size trees, crown traits related to structural geometry of branching pattern and space occupancy through phyllotaxis can be accurately evaluated in 3D, using computed tomography (CT) scanning data. We demonstrat...

  1. Crown traits of coniferous trees and their relation to shade tolerance can differ with leaf type: A biophysical demonstration using computed tomography scanning data

    OpenAIRE

    Pierre eDutilleul; Liwen eHan; Fernando eValladeres; Christian eMessier; Christian eMessier

    2015-01-01

    Plant light interception and shade tolerance are intrinsically related in that they involve structural, morphological and physiological adaptations to manage light capture for photosynthetic utilization, in order to sustain survival, development and reproduction. At the scale of small-size trees, crown traits related to structural geometry of branching pattern and space occupancy through phyllotaxis can be accurately evaluated in 3D, using computed tomography (CT) scanning data. We demonstrat...

  2. Proof-of-principle demonstration of Nb{sub 3}Sn superconducting radiofrequency cavities for high Q{sub 0} applications

    Energy Technology Data Exchange (ETDEWEB)

    Posen, S., E-mail: sep93@cornell.edu; Liepe, M.; Hall, D. L. [Cornell Laboratory for Accelerator-Based Sciences and Education, Ithaca, New York 14853 (United States)

    2015-02-23

    Many future particle accelerators require hundreds of superconducting radiofrequency (SRF) cavities operating with high duty factor. The large dynamic heat load of the cavities causes the cryogenic plant to make up a significant part of the overall cost of the facility. This contribution can be reduced by replacing standard niobium cavities with ones coated with a low-dissipation superconductor such as Nb{sub 3}Sn. In this paper, we present results for single cell cavities coated with Nb{sub 3}Sn at Cornell. Five coatings were carried out, showing that at 4.2 K, high Q{sub 0} out to medium fields was reproducible, resulting in an average quench field of 14 MV/m and an average 4.2 K Q{sub 0} at quench of 8 × 10{sup 9}. In each case, the peak surface magnetic field at quench was well above H{sub c1}, showing that it is not a limiting field in these cavities. The coating with the best performance had a quench field of 17 MV/m, exceeding gradient requirements for state-of-the-art high duty factor SRF accelerators. It is also shown that—taking into account the thermodynamic efficiency of the cryogenic plant—the 4.2 K Q{sub 0} values obtained meet the AC power consumption requirements of state-of-the-art high duty factor accelerators, making this a proof-of-principle demonstration for Nb{sub 3}Sn cavities in future applications.

  3. A method for high accuracy determination of equilibrium relative humidity

    DEFF Research Database (Denmark)

    Jensen, O.M.

    2012-01-01

    This paper treats a new method for measuring equilibrium relative humidity and equilibrium dew-point temperature of a material sample. The developed measuring device is described – a Dew-point Meter – which by means of so-called Dynamic Dew-point Analysis permits quick and very accurate...

  4. High Tide, Low Tide. Ocean Related Curriculum Activities.

    Science.gov (United States)

    Snively, Gloria

    The ocean affects all of our lives. Therefore, awareness of and information about the interconnections between humans and oceans are prerequisites to making sound decisions for the future. Project ORCA (Ocean Related Curriculum Activities) has developed interdisciplinary curriculum materials designed to meet the needs of students and teachers…

  5. Sports-related dentofacial trauma among high school students in ...

    African Journals Online (AJOL)

    Objectives: To determine the prevalence and pattern of occurrence of sports - related dentofacial injuries among athletes participating in Rugby and Football in Nairobi, Kenya. Design: A descriptive cross-sectional study. Setting: Seventeen Secondary schools participating in either or both Rugby tournaments and the ...

  6. ORIGINAL ARTICLES High AIDS-related mortality among young ...

    African Journals Online (AJOL)

    According to a technical report prepared by the South African. Medical Research Council,4 death registration improved from. 54% in 1990 to 89% in 2000, although underreporting persists in rural areas and with regard to patients without government- issued personal ID numbers. An additional problem relates to major ...

  7. New perovskite-related oxides having high dielectric constant ...

    Indian Academy of Sciences (India)

    Unknown

    static and dynamic random access memories, the static dielectric constant of the material. ¶Dedicated to .... 1100°C. It is also observed from the SEM pictures that the materials are highly dense .... Both these oxides merit attention for their.

  8. Creative thinking level of students with high capability in relations and functions by problem-based learning

    Science.gov (United States)

    Nurdyani, F.; Slamet, I.; Sujadi, I.

    2018-03-01

    This research was conducted in order to describe the creative thinking level of students with high capability in relations and functions with Problem Based Learning. The subjects of the research were students with high capability grade VIII at SMPIT Ibnu Abbas Klaten. This research is an qualitative descriptive research. The data were collected using observation, tests and interviews. The result showed that the creative thinking level of students with high capability in relations and functions by Problem Based Learning was at level 4 or very creative because students were able to demonstrate fluency, flexibility, and novelty.

  9. Demonstration of a high-intensity neutron source based on a liquid-lithium target for Accelerator based Boron Neutron Capture Therapy.

    Science.gov (United States)

    Halfon, S; Arenshtam, A; Kijel, D; Paul, M; Weissman, L; Berkovits, D; Eliyahu, I; Feinberg, G; Kreisel, A; Mardor, I; Shimel, G; Shor, A; Silverman, I; Tessler, M

    2015-12-01

    A free surface liquid-lithium jet target is operating routinely at Soreq Applied Research Accelerator Facility (SARAF), bombarded with a ~1.91 MeV, ~1.2 mA continuous-wave narrow proton beam. The experiments demonstrate the liquid lithium target (LiLiT) capability to constitute an intense source of epithermal neutrons, for Accelerator based Boron Neutron Capture Therapy (BNCT). The target dissipates extremely high ion beam power densities (>3 kW/cm(2), >0.5 MW/cm(3)) for long periods of time, while maintaining stable conditions and localized residual activity. LiLiT generates ~3×10(10) n/s, which is more than one order of magnitude larger than conventional (7)Li(p,n)-based near threshold neutron sources. A shield and moderator assembly for BNCT, with LiLiT irradiated with protons at 1.91 MeV, was designed based on Monte Carlo (MCNP) simulations of BNCT-doses produced in a phantom. According to these simulations it was found that a ~15 mA near threshold proton current will apply the therapeutic doses in ~1h treatment duration. According to our present results, such high current beams can be dissipated in a liquid-lithium target, hence the target design is readily applicable for accelerator-based BNCT. Copyright © 2015 Elsevier Ltd. All rights reserved.

  10. Computational Testing for Automated Preprocessing 2: Practical Demonstration of a System for Scientific Data-Processing Workflow Management for High-Volume EEG.

    Science.gov (United States)

    Cowley, Benjamin U; Korpela, Jussi

    2018-01-01

    Existing tools for the preprocessing of EEG data provide a large choice of methods to suitably prepare and analyse a given dataset. Yet it remains a challenge for the average user to integrate methods for batch processing of the increasingly large datasets of modern research, and compare methods to choose an optimal approach across the many possible parameter configurations. Additionally, many tools still require a high degree of manual decision making for, e.g., the classification of artifacts in channels, epochs or segments. This introduces extra subjectivity, is slow, and is not reproducible. Batching and well-designed automation can help to regularize EEG preprocessing, and thus reduce human effort, subjectivity, and consequent error. The Computational Testing for Automated Preprocessing (CTAP) toolbox facilitates: (i) batch processing that is easy for experts and novices alike; (ii) testing and comparison of preprocessing methods. Here we demonstrate the application of CTAP to high-resolution EEG data in three modes of use. First, a linear processing pipeline with mostly default parameters illustrates ease-of-use for naive users. Second, a branching pipeline illustrates CTAP's support for comparison of competing methods. Third, a pipeline with built-in parameter-sweeping illustrates CTAP's capability to support data-driven method parameterization. CTAP extends the existing functions and data structure from the well-known EEGLAB toolbox, based on Matlab, and produces extensive quality control outputs. CTAP is available under MIT open-source licence from https://github.com/bwrc/ctap.

  11. Demonstration of the postcommissural fibres of the fornix in short-inversion time inversion-recovery imaging on a high-field system

    Energy Technology Data Exchange (ETDEWEB)

    Saeki, N.; Kansaku, K.; Higuchi, Y.; Yamaura, A. [Dept. of Neurological Surgery, Chiba University School of Medicine (Japan); Kawano, K.; Iijima, T. [Electrotechnical Lab., Tsukuba (Japan); Inoue, N. [GE Yokagawa Medical Systems, Tokyo (Japan)

    2001-07-01

    Short-inversion time inversion-recovery (STIR) imaging using a 3 tesla system was assessed to reveal the postcommissural fibres (PF) of the fornix, which have rarely been highlighted neuroradiologically in the clinical setting. We studied 27 normal subjects. Sequence parameters were TR/TE/TI 8000/52/150 ms. STIR was expected to take advantage of the high signal-to-noise ratio of a high-field system, due to the long repetition time. PF were identifiable in axial and coronal slices in all cases. They were bordered anteriorly and superiorly by the anterior commissure and posteriorly and inferiorly by the mamillary body. Behind the anterior commissure, they ran in an arch-shaped posterior and inferior course in the hypothalamic nuclei and joined the mamillary body anterolaterally. They usually extended through three 3-mm slices (with 1 mm interslice gap) in anteroposterior and vertical dimensions. Little variation was observed in their course or size. Demonstration of the PF would provide a more detailed correlation of human neuroanatomy to hypothalamic function and individualised understanding of hypothalamic pathology and influence therapy. (orig.)

  12. Demonstration of the postcommissural fibres of the fornix in short-inversion time inversion-recovery imaging on a high-field system

    International Nuclear Information System (INIS)

    Saeki, N.; Kansaku, K.; Higuchi, Y.; Yamaura, A.; Kawano, K.; Iijima, T.; Inoue, N.

    2001-01-01

    Short-inversion time inversion-recovery (STIR) imaging using a 3 tesla system was assessed to reveal the postcommissural fibres (PF) of the fornix, which have rarely been highlighted neuroradiologically in the clinical setting. We studied 27 normal subjects. Sequence parameters were TR/TE/TI 8000/52/150 ms. STIR was expected to take advantage of the high signal-to-noise ratio of a high-field system, due to the long repetition time. PF were identifiable in axial and coronal slices in all cases. They were bordered anteriorly and superiorly by the anterior commissure and posteriorly and inferiorly by the mamillary body. Behind the anterior commissure, they ran in an arch-shaped posterior and inferior course in the hypothalamic nuclei and joined the mamillary body anterolaterally. They usually extended through three 3-mm slices (with 1 mm interslice gap) in anteroposterior and vertical dimensions. Little variation was observed in their course or size. Demonstration of the PF would provide a more detailed correlation of human neuroanatomy to hypothalamic function and individualised understanding of hypothalamic pathology and influence therapy. (orig.)

  13. High molecular weight FGF2 isoforms demonstrate canonical receptor-mediated activity and support human embryonic stem cell self-renewal

    Directory of Open Access Journals (Sweden)

    Denis Kole

    2017-05-01

    Full Text Available Basic fibroblast growth factor (FGF2 is a highly pleiotropic member of a large family of growth factors with a broad range of activities, including mitogenesis and angiogenesis (Ornitz et al., 1996; Zhang et al., 2006, and it is known to be essential for maintenance of balance between survival, proliferation, and self-renewal in human pluripotent stem cells (Eiselleova et al., 2009; Zoumaro-Djayoon et al., 2011. A single FGF2 transcript can be translated into five FGF2 protein isoforms, an 18 kDa low molecular weight (LMW isoform and four larger high molecular weight (HMW isoforms (Arese et al., 1999; Arnaud et al., 1999. As they are not generally secreted, high molecular weight (HMW FGF2 isoforms have predominantly been investigated intracellularly; only a very limited number of studies have investigated their activity as extracellular factors. Here we report over-expression, isolation, and biological activity of all recombinant human FGF2 isoforms. We show that HMW FGF2 isoforms can support self-renewal of human embryonic stem cells (hESCs in vitro. Exogenous supplementation with HMW FGF2 isoforms also activates the canonical FGFR/MAPK pathway and induces mitogenic activity in a manner similar to that of the 18 kDa FGF2 isoform. Though all HMW isoforms, when supplemented exogenously, are able to recapitulate LMW FGF2 activity to some degree, it appears that certain isoforms tend to do so more poorly, demonstrating a lesser functional response by several measures. A better understanding of isoform-specific FGF2 effects will lead to a better understanding of developmental and pathological FGF2 signaling.

  14. Losses of radionuclides related to high temperature ashing

    International Nuclear Information System (INIS)

    Carlsson, G.

    1985-01-01

    When measuring radionuclides in samples from the environment of nuclear power plants, a sample preparation step, such as high temperature ashing is often necessary. Althoug much used, this method is subject to controversy because of the risk of losses of several elements. A study, including the ashing of synthetically prepared samples has been undertaken. Controlled and moderate temperature rise rate and a final temperature not exceeding 550 deg. C has been shown vital for recovery

  15. Brief Report: Theory of Mind, Relational Reasoning, and Social Responsiveness in Children with and without Autism--Demonstration of Feasibility for a Larger-Scale Study

    Science.gov (United States)

    Pruett, John R., Jr.; Kandala, Sridhar; Petersen, Steven E.; Povinelli, Daniel J.

    2015-01-01

    Understanding the underpinnings of social responsiveness and theory of mind (ToM) will enhance our knowledge of autism spectrum disorder (ASD). We hypothesize that higher-order relational reasoning (higher-order RR: reasoning necessitating integration of relationships among multiple variables) is necessary but not sufficient for ToM, and that…

  16. Color changes in pork in relation to high pressure treatment

    DEFF Research Database (Denmark)

    Bak, Kathrine Holmgaard

    treatment and during a six-day storage period was investigated via surface reflectance. Spectroscopic studies (in the form of surface reflectance, UV-vis, and circular dichroism) on the effect of HP treatment on the soluble protein fraction of porcine LD were conducted attempting to explain the color......-denatured ferric myoglobin species was not similar to the heat-denatured pigment, ferrihemochrome, but instead a closely related species sharing features of denatured gobin, ferric iron, and brown color. The reversibility of the pressure-induced changes often observed for various myoglobin forms in solution were...

  17. Natural Selection on Genes Related to Cardiovascular Health in High-Altitude Adapted Andeans.

    Science.gov (United States)

    Crawford, Jacob E; Amaru, Ricardo; Song, Jihyun; Julian, Colleen G; Racimo, Fernando; Cheng, Jade Yu; Guo, Xiuqing; Yao, Jie; Ambale-Venkatesh, Bharath; Lima, João A; Rotter, Jerome I; Stehlik, Josef; Moore, Lorna G; Prchal, Josef T; Nielsen, Rasmus

    2017-11-02

    The increase in red blood cell mass (polycythemia) due to the reduced oxygen availability (hypoxia) of residence at high altitude or other conditions is generally thought to be beneficial in terms of increasing tissue oxygen supply. However, the extreme polycythemia and accompanying increased mortality due to heart failure in chronic mountain sickness most likely reduces fitness. Tibetan highlanders have adapted to high altitude, possibly in part via the selection of genetic variants associated with reduced polycythemic response to hypoxia. In contrast, high-altitude-adapted Quechua- and Aymara-speaking inhabitants of the Andean Altiplano are not protected from high-altitude polycythemia in the same way, yet they exhibit other adaptive features for which the genetic underpinnings remain obscure. Here, we used whole-genome sequencing to scan high-altitude Andeans for signals of selection. The genes showing the strongest evidence of selection-including BRINP3, NOS2, and TBX5-are associated with cardiovascular development and function but are not in the response-to-hypoxia pathway. Using association mapping, we demonstrated that the haplotypes under selection are associated with phenotypic variations related to cardiovascular health. We hypothesize that selection in response to hypoxia in Andeans could have vascular effects and could serve to mitigate the deleterious effects of polycythemia rather than reduce polycythemia itself. Copyright © 2017. Published by Elsevier Inc.

  18. Magnetically-related properties of bismuth containing high Tc superconductors

    Science.gov (United States)

    Vezzoli, Gary C.; Chen, M. F.; Craver, F.; Safari, A.; Moon, B. M.; Lalevic, B.; Burke, Terence; Shoga, M.

    1990-08-01

    The effect of magnetic fields to 15 T on electrical resistance has been measured for the BiSrCaCuO superconductor at precise temperatures during the transition to the superconducting state from pre-onset conditions to essentially zero resistance conditions. The results show that the temperature at which the magnetic field causes a divergence in the resistance versus 1000/ T curve is approximately the same temperature as the value at which, during cooling, the positive Hall coefficient begins its abrupt descent to zero. This temperature gives the best measure of Tc. It is also shown that small oscillations of low frequency start near onset conditions, the amplitude of which at a given temperature is B-field dependent. Additionally, Hall effect studies as a function of temperature at 4 T in three separate experiments (including high Tc BiSrCaCu PbO of > 90% theoretical density) show that sharp delta-function-like peaks in + RH are observed near Tc and are superimposed on a broader maximum. The Hall data are explicable in terms of exciton formation and ionization. The bound holes associated with these excitons are believed to be the mediators producing Cooper-pairing, and scale very well with Tc for all the known high Tc oxides.

  19. Pilot-scale demonstration of the OSCAR process for high-temperature multipollutant control of coal combustion flue gas, using carbonated fly ash and mesoporous calcium carbonate

    Energy Technology Data Exchange (ETDEWEB)

    Gupta, H.; Thomas, T.J.; Park, A.H.A.; Iyer, M.V.; Gupta, P.; Agnihotri, R.; Jadhav, R.A.; Walker, H.W.; Weavers, L.K.; Butalia, T.; Fan, L.S. [Ohio State University, Columbus, OH (United States)

    2007-07-15

    A pilot-scale study of the Ohio State Carbonation Ash Reactivation (OSCAR) process was performed to demonstrate the reactivity of two novel calcium-based sorbents toward sulfur and trace heavy metal (arsenic, selenium, and mercury) capture in the furnace sorbent injection (FSI) mode on a 0.365 m{sup 3}/s slipstream of a bituminous coal-fired stoker boiler. The sorbents were synthesized by bubbling CO{sub 2} to precipitate calcium carbonate (a) from the unreacted calcium present in the lime spray dryer ash and (b) from calcium hydroxide slurry that contained a negatively charged dispersant. The heterogeneous reaction between these sorbents and SO{sub 2} gas occurred under entrained flow conditions by injecting fine sorbent powders into the flue gas slipstream. The reacted sorbents were captured either in a hot cyclone (about 650{sup o}C) or in the relatively cooler downstream baghouse (about 230{sup o}C). The baghouse samples indicated about 90% toward sulfation and captured arsenic, selenium and mercury to 800 ppmw, 175 ppmw and 3.6 ppmw, respectively.

  20. Environmental impact assessment relating to the proposed siting of the European Demonstration Fast Reactor Fuel Reprocessing Plant (EDRP) at Dounreay, Caithness

    Energy Technology Data Exchange (ETDEWEB)

    1985-01-01

    This Report assesses the likely environmental impact of the European Demonstration Fast Reactor Fuel Reprocessing Plant (EDRP) which the United Kingdom Atomic Authority (UKAEA) and British Nuclear Fuels plc (BNFL) are proposing to build at the Dounreay Nuclear Power Development Establishment (DNE), Caithness and for which they have sought outline planning permission. The format of the report has been designed to meet the guidelines set out in the European Economic Community's Directive (85/337/EEC) concerning the assessment of the environmental effects of certain public and private projects. The Report is presented in four parts: Part A gives information on the present environment at DNE and explains in detail the environmental monitoring which has been carried out there since 1956. Part B describes the proposed development. Part C assesses the likely effects of the proposed development on the environment. Part D lists all the references quoted in this Report together with a bibliography of other sources of information relevant to the proposed development.

  1. A 2-stage ovarian cancer screening strategy using the Risk of Ovarian Cancer Algorithm (ROCA) identifies early-stage incident cancers and demonstrates high positive predictive value.

    Science.gov (United States)

    Lu, Karen H; Skates, Steven; Hernandez, Mary A; Bedi, Deepak; Bevers, Therese; Leeds, Leroy; Moore, Richard; Granai, Cornelius; Harris, Steven; Newland, William; Adeyinka, Olasunkanmi; Geffen, Jeremy; Deavers, Michael T; Sun, Charlotte C; Horick, Nora; Fritsche, Herbert; Bast, Robert C

    2013-10-01

    A 2-stage ovarian cancer screening strategy was evaluated that incorporates change of carbohydrate antigen 125 (CA125) levels over time and age to estimate risk of ovarian cancer. Women with high-risk scores were referred for transvaginal ultrasound (TVS). A single-arm, prospective study of postmenopausal women was conducted. Participants underwent an annual CA125 blood test. Based on the Risk of Ovarian Cancer Algorithm (ROCA) result, women were triaged to next annual CA125 test (low risk), repeat CA125 test in 3 months (intermediate risk), or TVS and referral to a gynecologic oncologist (high risk). A total of 4051 women participated over 11 years. The average annual rate of referral to a CA125 test in 3 months was 5.8%, and the average annual referral rate to TVS and review by a gynecologic oncologist was 0.9%. Ten women underwent surgery on the basis of TVS, with 4 invasive ovarian cancers (1 with stage IA disease, 2 with stage IC disease, and 1 with stage IIB disease), 2 ovarian tumors of low malignant potential (both stage IA), 1 endometrial cancer (stage I), and 3 benign ovarian tumors, providing a positive predictive value of 40% (95% confidence interval = 12.2%, 73.8%) for detecting invasive ovarian cancer. The specificity was 99.9% (95% confidence interval = 99.7%, 100%). All 4 women with invasive ovarian cancer were enrolled in the study for at least 3 years with low-risk annual CA125 test values prior to rising CA125 levels. ROCA followed by TVS demonstrated excellent specificity and positive predictive value in a population of US women at average risk for ovarian cancer. Copyright © 2013 American Cancer Society.

  2. Comparison of nuclear irradiation parameters of fusion breeder materials in high flux fission test reactors and a fusion power demonstration reactor

    International Nuclear Information System (INIS)

    Fischer, U.; Herring, S.; Hogenbirk, A.; Leichtle, D.; Nagao, Y.; Pijlgroms, B.J.; Ying, A.

    2000-01-01

    Nuclear irradiation parameters relevant to displacement damage and burn-up of the breeder materials Li 2 O, Li 4 SiO 4 and Li 2 TiO 3 have been evaluated and compared for a fusion power demonstration reactor and the high flux fission test reactor (HFR), Petten, the advanced test reactor (ATR, INEL) and the Japanese material test reactor (JMTR, JAERI). Based on detailed nuclear reactor calculations with the MCNP Monte Carlo code and binary collision approximation (BCA) computer simulations of the displacement damage in the polyatomic lattices with MARLOWE, it has been investigated how well the considered HFRs can meet the requirements for a fusion power reactor relevant irradiation. It is shown that a breeder material irradiation in these fission test reactors is well suited in this regard when the neutron spectrum is well tailored and the 6 Li-enrichment is properly chosen. Requirements for the relevant nuclear irradiation parameters such as the displacement damage accumulation, the lithium burn-up and the damage production function W(T) can be met when taking into account these prerequisites. Irradiation times in the order of 2-3 full power years are necessary for the HFR to achieve the peak values of the considered fusion power Demo reactor blanket with regard to the burn-up and, at the same time, the dpa accumulation

  3. Execution techniques and approach for high level radioactive waste disposal in Japan: Demonstration of geological disposal techniques and implementation approach of HLW project

    International Nuclear Information System (INIS)

    Kawanishi, M.; Komada, H.; Kitayama, K.; Akasaka, H.; Tsuchi, H.

    2001-01-01

    In Japan, the high-level radioactive waste (HLW) disposal project is expected to start fully after establishment of the implementing organization, which is planned around the year 2000 and to dispose the wastes in the 2030s to at latest in the middle of 2040s. Considering each step in the implementation of the HLW disposal project in Japan, this paper discusses the execution procedure for HLW disposal project, such as the selection of candidate/planned disposal sites, the construction and operation of the disposal facility, the closure and decommissioning of facilities, and the institutional control and monitoring after the closure of disposal facility, from a technical viewpoint for the rational execution of the project. Furthermore, we investigate and propose some ideas for the concept of the design of geological disposal facility, the validation and demonstration of the reliability on the disposal techniques and performance assessment methods at a candidate/planned site. Based on these investigation results, we made clear a milestone for the execution of the HLW disposal project in Japan. (author)

  4. Real-Time On-Board Airborne Demonstration of High-Speed On-Board Data Processing for Science Instruments (HOPS)

    Science.gov (United States)

    Beyon, Jeffrey Y.; Ng, Tak-Kwong; Davis, Mitchell J.; Adams, James K.; Bowen, Stephen C.; Fay, James J.; Hutchinson, Mark A.

    2015-01-01

    The project called High-Speed On-Board Data Processing for Science Instruments (HOPS) has been funded by NASA Earth Science Technology Office (ESTO) Advanced Information Systems Technology (AIST) program since April, 2012. The HOPS team recently completed two flight campaigns during the summer of 2014 on two different aircrafts with two different science instruments. The first flight campaign was in July, 2014 based at NASA Langley Research Center (LaRC) in Hampton, VA on the NASA's HU-25 aircraft. The science instrument that flew with HOPS was Active Sensing of CO2 Emissions over Nights, Days, and Seasons (ASCENDS) CarbonHawk Experiment Simulator (ACES) funded by NASA's Instrument Incubator Program (IIP). The second campaign was in August, 2014 based at NASA Armstrong Flight Research Center (AFRC) in Palmdale, CA on the NASA's DC-8 aircraft. HOPS flew with the Multifunctional Fiber Laser Lidar (MFLL) instrument developed by Excelis Inc. The goal of the campaigns was to perform an end-to-end demonstration of the capabilities of the HOPS prototype system (HOPS COTS) while running the most computationally intensive part of the ASCENDS algorithm real-time on-board. The comparison of the two flight campaigns and the results of the functionality tests of the HOPS COTS are presented in this paper.

  5. Mnemonic discrimination relates to perforant path integrity: An ultra-high resolution diffusion tensor imaging study.

    Science.gov (United States)

    Bennett, Ilana J; Stark, Craig E L

    2016-03-01

    Pattern separation describes the orthogonalization of similar inputs into unique, non-overlapping representations. This computational process is thought to serve memory by reducing interference and to be mediated by the dentate gyrus of the hippocampus. Using ultra-high in-plane resolution diffusion tensor imaging (hrDTI) in older adults, we previously demonstrated that integrity of the perforant path, which provides input to the dentate gyrus from entorhinal cortex, was associated with mnemonic discrimination, a behavioral outcome designed to load on pattern separation. The current hrDTI study assessed the specificity of this perforant path integrity-mnemonic discrimination relationship relative to other cognitive constructs (identified using a factor analysis) and white matter tracts (hippocampal cingulum, fornix, corpus callosum) in 112 healthy adults (20-87 years). Results revealed age-related declines in integrity of the perforant path and other medial temporal lobe (MTL) tracts (hippocampal cingulum, fornix). Controlling for global effects of brain aging, perforant path integrity related only to the factor that captured mnemonic discrimination performance. Comparable integrity-mnemonic discrimination relationships were also observed for the hippocampal cingulum and fornix. Thus, whereas perforant path integrity specifically relates to mnemonic discrimination, mnemonic discrimination may be mediated by a broader MTL network. Copyright © 2015 Elsevier Inc. All rights reserved.

  6. Probing the distance-duality relation with high- z data

    Energy Technology Data Exchange (ETDEWEB)

    Holanda, R.F.L. [Departamento de Física, Universidade Estadual da Paraíba, 58429-500, Campina Grande—PB (Brazil); Busti, V.C. [Departamento de Física Matemática, Instituto de Física, Universidade de São Paulo, CEP 05508-090, São Paulo—SP (Brazil); Lima, F.S. [Departamento de Física, Universidade Federal de Campina Grande, 58429-900, Campina Grande—PB (Brazil); Alcaniz, J.S., E-mail: holanda@uepb.edu.br, E-mail: viniciusbusti@gmail.com, E-mail: limasdl@bol.com.br, E-mail: alcaniz@on.br [Departamento de Astronomia, Observatório Nacional, 20921-400, Rio de Janeiro—RJ (Brazil)

    2017-09-01

    Measurements of strong gravitational lensing jointly with type Ia supernovae (SNe Ia) observations have been used to test the validity of the cosmic distance duality relation (CDDR), D{sub L}( z )/[(1+ z ){sup 2D{sub A}}( z )]=η=1, where D{sub L}(z) and D{sub A}(z) are the luminosity and the angular diameter distances to a given redshift z , respectively. However, several lensing systems lie in the interval 1.4 ≤ z ≤ 3.6 i.e., beyond the redshift range of current SNe Ia compilations ( z ≈ 1.50), which prevents this kind of test to be fully explored. In this paper, we circumvent this problem by testing the CDDR considering observations of strong gravitational lensing along with SNe Ia and (a subsample from) the latest gamma-ray burst distance modulus data, whose redshift range is 0.033 ≤ z ≤ 9.3. We parameterize their luminosity distances with a second degree polynomial function and search for possible deviations from the CDDR validity by using four different η( z ) functions: η( z )=1+η{sub 0z}, η( z )=1+η{sub 0z}/(1+ z ), η( z )=(1+ z ){sup η{sub 0}} and η( z )=1+η{sub 0ln}(1+ z ). Unlike previous tests done at redshifts lower than 1.50, the likelihood for η{sub 0} depends strongly on the η( z ) function considered, but we find no significant deviation from the CDDR validity (η{sub 0}=0). However, our analyses also point to the fact that caution is needed when one fits data in higher redshifts to test the CDDR as well as a better understanding of the mass distribution of lenses also is required for more accurate results.

  7. Testing high brightness LEDs relative to application environment

    Science.gov (United States)

    Singer, Jeffrey; Mangum, Scott; Lundberg, John

    2006-08-01

    Application of light emitting diodes is expanding as the luminous output and efficiencies of these devices improve. At the same time, the number of LED package types is increasing, making it challenging to determine the appropriate device for use in lighting product designs. A range of factors should be considered when selecting a LED for an application including color coordinates, luminous efficacy, cost, lumen maintenance, application life, packaging and manufacturability. Additional complexities can be introduced as LED packages become obsolete and replacement parts must be selected. The replacement LED characteristics must be understood and assessed against the parameters of the original device, in order to determine if the change will be relatively simple or will force other end-product changes. While some characteristics are readily measured and compared, other factors, such as lumen maintenance, are difficult to verify. This paper will discuss the characteristics of a LED that should be considered during the design process as well as methods to validate these characteristics, particularly those which are not typically on data sheets or, are critical to the design and warrant additional validation. Particular attention will be given to LED lumen maintenance. While published manufacturer data typically provides temperature versus performance curves, the data may not be useful depending upon the application's operating environment. Models must be created to estimate the LED's junction temperature and degradation curve at the applied temperature in order to develop a more precise life estimate. This paper presents one approach to a LED device life and performance study designed with application environments in mind.

  8. Brief Report: Theory of Mind, Relational Reasoning, and Social Responsiveness in Children With and Without Autism: Demonstration of Feasibility for a Larger-Scale Study.

    Science.gov (United States)

    Pruett, John R; Kandala, Sridhar; Petersen, Steven E; Povinelli, Daniel J

    2015-07-01

    Understanding the underpinnings of social responsiveness and theory of mind (ToM) will enhance our knowledge of autism spectrum disorder (ASD). We hypothesize that higher-order relational reasoning (higher-order RR: reasoning necessitating integration of relationships among multiple variables) is necessary but not sufficient for ToM, and that social responsiveness varies independently of higher-order RR. A pilot experiment tested these hypotheses in n = 17 children, 3-14, with and without ASD. No child failing 2nd-order RR passed a false belief ToM test. Contrary to prediction, Social Responsiveness Scale scores did correlate with 2nd-order RR performance, likely due to sample characteristics. It is feasible to translate this comparative cognition-inspired line of inquiry for full-scale studies of ToM, higher-order RR, and social responsiveness in ASD.

  9. Spent fuel pyroprocessing demonstration

    International Nuclear Information System (INIS)

    McFarlane, L.F.; Lineberry, M.J.

    1995-01-01

    A major element of the shutdown of the US liquid metal reactor development program is managing the sodium-bonded spent metallic fuel from the Experimental Breeder Reactor-II to meet US environmental laws. Argonne National Laboratory has refurbished and equipped an existing hot cell facility for treating the spent fuel by a high-temperature electrochemical process commonly called pyroprocessing. Four products will be produced for storage and disposal. Two high-level waste forms will be produced and qualified for disposal of the fission and activation products. Uranium and transuranium alloys will be produced for storage pending a decision by the US Department of Energy on the fate of its plutonium and enriched uranium. Together these activities will demonstrate a unique electrochemical treatment technology for spent nuclear fuel. This technology potentially has significant economic and technical advantages over either conventional reprocessing or direct disposal as a high-level waste option

  10. High energy density physics issues related to Future Circular Collider

    Science.gov (United States)

    Tahir, N. A.; Burkart, F.; Schmidt, R.; Shutov, A.; Wollmann, D.; Piriz, A. R.

    2017-07-01

    A design study for a post-Large Hadron Collider accelerator named, Future Circular Collider (FCC), is being carried out by the International Scientific Community. A complete design report is expected to be ready by spring 2018. The FCC will accelerate two counter rotating beams of 50 TeV protons in a tunnel having a length (circumference) of 100 km. Each beam will be comprised of 10 600 proton bunches, with each bunch having an intensity of 1011 protons. The bunch length is of 0.5 ns, and two neighboring bunches are separated by 25 ns. Although there is an option for 5 ns bunch separation as well, in the present studies, we consider the former case only. The total energy stored in each FCC beam is about 8.5 GJ, which is equivalent to the kinetic energy of Airbus 380 (560 t) flying at a speed of 850 km/h. Machine protection is a very important issue while operating with such powerful beams. It is important to have an estimate of the damage caused to the equipment and accelerator components due to the accidental release of a partial or total beam at a given point. For this purpose, we carried out numerical simulations of full impact of one FCC beam on an extended solid copper target. These simulations have been done employing an energy deposition code, FLUKA, and a two-dimensional hydrodynamic code, BIG2, iteratively. This study shows that although the static range of a single FCC proton and its shower is about 1.5 m in solid copper, the entire beam will penetrate around 350 m into the target. This substantial increase in the range is due to the hydrodynamic tunneling of the beam. Our calculations also show that a large part of the target will be converted into high energy density matter including warm dense matter and strongly coupled plasmas.

  11. Surface morphology of chitin highly related with the isolated body part of butterfly (Argynnis pandora).

    Science.gov (United States)

    Kaya, Murat; Bitim, Betül; Mujtaba, Muhammad; Koyuncu, Turgay

    2015-11-01

    This study was conducted to understand the differences in the physicochemical properties of chitin samples isolated from the wings and the other body parts except the wings (OBP) of a butterfly species (Argynnis pandora). The same isolation method was used for obtaining chitin specimens from both types of body parts. The chitin content of the wings (22%) was recorded as being much higher than the OBP (8%). The extracted chitin samples were characterized via FT-IR, TGA, XRD, SEM, and elemental analysis techniques. Results of these characterizations revealed that the chitins from both structures (wings and OBP) were very similar, except for their surface morphologies. SEM results demonstrated one type of surface morphology for the wings and four different surface morphologies for the OBP. Therefore, it can be hypothesized that the surface morphology of the chitin is highly related with the body part. Copyright © 2015 Elsevier B.V. All rights reserved.

  12. First Detections of the [N II] 122 micron Line at High Redshift: Demonstrating the Utility of the Line for Studying Galaxies in the Early Universe

    Science.gov (United States)

    Ferkinhoff, Carl; Brisbin, Drew; Nikola, Thomas; Parshley, Stephen C.; Stacey, Gordon J.; Phillips, Thomas G.; Falgarone, Edith; Benford, Dominic J.; Staguhn, Johannes G.; Tucker, Carol E.

    2011-01-01

    We report the first detections of the [N II] 122 micron line from a high-redshift galaxy. The line was strongly (>6(sigma)) detected from SMMJ02399-0136, and H1413 + 117 (the Cloverleaf QSO) using the Redshift (zeta) and Early Universe Spectrometer on the Caltech Submillimeter Observatory. The lines from both sources are quite bright with line to far-infrared (FIR) continuum luminosity ratios that are approx.7.0 x 10(exp -4) (Cloverleaf) and 2.1 x 10(exo -3) (SMMJ02399). With ratios 2-10 times larger than the average value for nearby galaxies, neither source exhibits the line to continuum deficits seen in nearby sources. The line strengths also indicate large ionized gas fractions, approx.8%-17% of the molecUlar gas mass. The [O III]/[N II] line ratio is very sensitive to the effective temperature of ionizing stars and the ionization parameter for emission arising in the narrow-line region (NLR) of an active galactic nucleus (AGN). Using Our previous detection of the [O III] 88 micron line, the [O III]/[N II]line ratio for SMMJ02399-0136 indicates that the dominant source of the line emission is either stellar H II regions ionized by O9.5 stars, or the NLR of the AGN with ionization parameter log(U) = -3.3 to -4.0. A composite system, where 30%-50% of the FIR lines arise in the NLR also matches the data. The Cloverleaf is best modeled by a superposition of approx.200 M82-like starbursts accounting for all of the FIR emission and 43% of the [N II]line. The remainder may come from the NLR. This war!< demonstrates the utility of the [N II] and [O III] lines in constraining properties of the ionized medium.

  13. First Detections of the [NII] 122 Micrometer Line at High Redshift: Demonstrating the Utility of the Line for Studying Galaxies in the Early Universe

    Science.gov (United States)

    Ferkinhoff, Carl; Brisbin, Drew; Nikola, Thomas; Parshley, Stephen C.; Stacey, Gordon J.; Phillips, Thomas G.; Falgarone, Edith; Benford, Dominic J.; Staguhn, Johannes G.; Tucker, Carol E.

    2011-01-01

    We report the first detections of the [NIl] 122 {\\mu} m line from a high redshift galaxy. The line was strongly (> 6{\\sigma}) detected from SMMJ02399-0136, and HI413+ 117 (the Cloverleaf QSO) using the Redshift(z) and Early Universe Spectrometer (ZEUS) on the CSO. The lines from both sources are quite bright with line-to-FIR continuum luminosity ratios that are approx.7.0x10(exp -4) (Cloverleaf) and 2.1x10(exp -3) (SMMJ02399). With ratios 2-10 times larger than the average value for nearby galaxies, neither source exhibits the line-to-continuum deficits seen in nearby sources. The line strengths also indicate large ionized gas fractions, approx.8 to 17% of the molecular gas mass. The [OIII]/[NII] line ratio is very sensitive to the effective temperature of ionizing stars and the ionization parameter for emission arising in the narrow-line region (NLR) of an AGN. Using our previous detection of the [01II] 88 {\\mu}m line, the [OIII]/ [NIl] line ratio for SMMJ02399-0136 indicates the dominant source of the line emission is either stellar HII regions ionized by 09.5 stars, or the NLR of the AGN with ionization parameter 10g(U) = -3.3 to -4.0. A composite system, where 30 to 50% of the FIR lines arise in the NLR also matches the data. The Cloverleaf is best modeled by a superposition of approx.200 M82like starbursts accounting for all of the FIR emission and 43% of the [NIl] line. The remainder may come from the NLR. This work demonstrates the utility of the [NIl] and [OIII] lines in constraining properties of the ionized medium.

  14. 3 T MR 3D fast imaging employing steady state acquisition demonstrating branches of intraparotid facial nerve, parotid duct, and relation with parotid tumors

    International Nuclear Information System (INIS)

    Li Yan; Li Chuanting; Zhang Dongsheng; Ai Bin; Zhang Weidong; Wu Lebin

    2010-01-01

    Objective: To investigate the usefulness of 3 T MRI 3D-FIESTA in the evaluation of the intraparotid components of the facial nerve and parotid duct, and compare them with surgical findings. Methods: Twenty-two cases with parotid benign tumors were scanned with conventional and 3D-FIESTA sequences on 3 T MRI scanner. Postprocessed multiplanar images were obtained with the workstation. Parotid ducts and facial nerves and tumors were identified on these images. The relationship of the tumors to the facial nerves and Parotid ducts was confirmed at surgery. Results: Various types of parotid benign tumors had their characteristics on 3 T MR imaging. Parotid benign tumors mainly showed hypo-intensity on T 1 WI in 21 cases, and hyper-intensity on T 2 WI in 22 cases. But on 3D-FIESTA images, they appeared hypointensity (10 cases) or high intensity (12 cases) due to different types. Facial nerves in parotid appeared as linear structures with hypo-inteusity. The indication of the main trunks were 16 and 18 cases for T 1 WI and T 2 WI images, while on 3D-FIESTA images, the main trunks and cervicofacial and temporofacial divisions of the facial nerves were found in 22, 21,22 cases. Parotid ducts appeared as structures with hypo-intensity on T 1 WI and hyper-intensity on multiplanar images (14, 20, 22 cases). Compared with surgical results, the main trunks of the facial nerve were correctly showed by 3D-FIESTA images in 20 cases. However, in 2 cases they were not located in the operation because of shifting. Conclusion: 3 T MR 3D-FIESTA imaging could depict the extracranial facial nerve and the parotid duct in the parotid gland, which is useful for preoperative evaluation of parotid gland tumors. (authors)

  15. 3D-FIESTA MRI at 3 T demonstrating branches of the intraparotid facial nerve, parotid ducts and relation with benign parotid tumours

    International Nuclear Information System (INIS)

    Li Chuanting; Li Yan; Zhang Dongsheng; Yang Zhenzhen; Wu Lebin

    2012-01-01

    Aim: To investigate the usefulness of three-dimensional (3D) fast imaging employing steady state precession (FIESTA) magnetic resonance imaging (MRI) at 3 T in evaluating the intraparotid components of the facial nerve and parotid ducts, and to compare the MRI images with surgical findings. Materials and methods: Thirty-one cases of benign parotid tumours were studied with conventional and 3D FIESTA MRI sequences at 3T using a head coil. The most clinically useful 3D FIESTA images were acquired at parameters of 4.9 ms repetition time (TR); 1.5 effective echo time (TEeff); a flip of 55°, a field of view of 18 to 20 cm, a matrix of 512 × 320, an axial plane, no gaps, and a section thickness of 1 mm. Post-processed multiplanar images were obtained with an Advantage Windows (AW sdc 4.3) workstation. Parotid ducts, facial nerves, and tumours were identified on these images. The relationship of the tumours to the facial nerves and parotid ducts was confirmed at surgery. Results: The facial nerves appeared as linear structures of low intensity. The main trunk of the facial nerve was identified bilaterally in 93.5% of the 3D-FIESTA sequence images. Parotid ducts appeared as structures of high intensity on multiplanar 3D-FIESTA images (100%). The relationships of the tumours with the cervicofacial and temporofacial divisions of the facial nerve were correctly diagnosed in 26 of 31 cases (83.9%) using 3D-FIESTA sequence images. Conclusion: 3D-FIESTA MRI at 3 T depicted the main trunk, cervicofacial and temporofacial divisions of the facial nerve, and the main parotid duct. It is useful for preoperative evaluation of parotid gland tumours.

  16. Waste and Disposal: Demonstration

    International Nuclear Information System (INIS)

    Neerdael, B.; Buyens, M.; De Bruyn, D.; Volckaert, G.

    2002-01-01

    Within the Belgian R and D programme on geological disposal, demonstration experiments have become increasingly important. In this contribution to the scientific report 2001, an overview is given of SCK-CEN's activities and achievements in the field of large-scale demonstration experiments. In 2001, main emphasis was on the PRACLAY project, which is a large-scale experiment to demonstrate the construction and the operation of a gallery for the disposal of HLW in a clay formation. The PRACLAY experiment will contribute to enhance understanding of water flow and mass transport in dense clay-based materials as well as to improve the design of the reference disposal concept. In the context of PRACLAY, a surface experiment (OPHELIE) has been developed to prepare and to complement PRACLAY-related experimental work in the HADES Underground Research Laboratory. In 2001, efforts were focussed on the operation of the OPHELIE mock-up. SCK-CEN also contributed to the SELFRAC roject which studies the self-healing of fractures in a clay formation

  17. Demonstration of HITEX

    International Nuclear Information System (INIS)

    Morrison, H.D.; Woodall, K.B.

    1993-01-01

    A model reactor for HITEX successfully demonstrated the concept of high-temperature isotopic exchange in a closed loop simulating the conditions for fusion fuel cleanup. The catalyst of platinum on alumina pellets provided a surface area large enough to operate the reactor at 400 degrees celsius with flow rates up to 2 L/min. A 15-L tank containing a mixture of 4% CD 4 in H 2 was depleted in deuterium within 75 minutes down to 100 ppm HD above the natural concentration of HD in the make-up hydrogen stream. The application to tritium removal from tritiated impurities in a hydrogen stream will work as well or better

  18. AIDS-Related Non-Hodgkin's Lymphoma in the Era of Highly Active Antiretroviral Therapy

    Directory of Open Access Journals (Sweden)

    Prakash Vishnu

    2012-01-01

    Full Text Available In economically developed countries, AIDS-related lymphoma (ARL accounts for a large proportion of malignances in HIV-infected individuals. Since the introduction of highly active anti-retroviral therapy (HAART in 1996, epidemiology and prognosis of ARL have changed. While there is a slight increase in the incidence of Hodgkin’s lymphoma in HIV-infected individuals, use of HAART has contributed to a decline in the incidence of non-Hodgkin’s lymphoma (NHL and also a decrease in the overall incidence of ARL. Strategies that employ HAART, improved supportive care, and the use of Rituximab with multi-agent chemotherapy have contributed to improved rates of complete remission and survival of patients with ARL that rival those seen in stage and histology matched HIV negative NHL patients. Most recent clinical trials demonstrate better outcomes with the use of rituximab in ARL. Tumor histogenesis (germinal center vs. non-germinal center origin is associated with lymphoma-specific outcomes in the setting of AIDS-related diffuse-large B cell lymphoma. High-dose chemotherapy (HDCT and autologous stem cell rescue (ASCT can be effective for a subset of patients with relapsed ARL. HIV sero-status alone should not preclude consideration of ASCT in the setting of ARL relapse. Clinical trials investigating the role of allogeneic hematopoietic stem cell transplant in ARL are currently underway.

  19. Demonstrating a New Census of Infrared Galaxies with ALMA (DANCING-ALMA). I. FIR Size and Luminosity Relation at z = 0-6 Revealed with 1034 ALMA Sources

    Science.gov (United States)

    Fujimoto, Seiji; Ouchi, Masami; Shibuya, Takatoshi; Nagai, Hiroshi

    2017-11-01

    We present the large statistics of the galaxy effective radius R e in the rest-frame far-infrared (FIR) wavelength {R}{{e}({FIR})} obtained from 1627 Atacama Large Millimeter/submillimeter Array (ALMA) 1 mm band maps that become public by 2017 July. Our ALMA sample consists of 1034 sources with the star formation rate ˜ 100{--}1000 {M}⊙ {{yr}}-1 and the stellar mass ˜ {10}10{--}{10}11.5 {M}⊙ at z = 0-6. We homogeneously derive {R}{{e}({FIR})} and FIR luminosity L FIR of our ALMA sources via the uv-visibility method with the exponential disk model, carefully evaluating selection and measurement incompletenesses by realistic Monte-Carlo simulations. We find that there is a positive correlation between {R}{{e}({FIR})} and L FIR at the >99% significance level. The best-fit power-law function, {R}{{e}({FIR})}\\propto {L}{FIR}α , provides α =0.28+/- 0.07, and shows that {R}{{e}({FIR})} at a fixed L FIR decreases toward high redshifts. The best-fit α and the redshift evolution of {R}{{e}({FIR})} are similar to those of R e in the rest-frame UV (optical) wavelength {R}{{e}({UV})} ({R}{{e}({Opt}.)}) revealed by Hubble Space Telescope (HST) studies. We identify that our ALMA sources have significant trends of {R}{{e}({FIR})}≲ {R}{{e}({UV})} and {R}{{e}({Opt}.)}, which suggests that the dusty starbursts take place in compact regions. Moreover, {R}{{e}({FIR})} of our ALMA sources is comparable to {R}{{e}({Opt}.)} of quiescent galaxies at z ˜ 1-3 as a function of stellar mass, supporting the evolutionary connection between these two galaxy populations. We also investigate rest-frame UV and optical morphologies of our ALMA sources with deep HST images, and find that ˜30%-40% of our ALMA sources are classified as major mergers. This indicates that dusty starbursts are triggered by not only the major mergers but also the other mechanism(s).

  20. Buried Waste Integrated Demonstration lessons learned: 1993 technology demonstrations

    International Nuclear Information System (INIS)

    Kostelnik, K.M.; Owens, K.J.

    1994-01-01

    An integrated technology demonstration was conducted by the Buried Waste Integrated Demonstration (BWID) at the Idaho National Engineering Laboratory Cold Test Pit in the summer of 1993. This program and demonstration was sponsored by the US Department of Energy Office of Technology Development. The demonstration included six technologies representing a synergistic system for the characterization and retrieval of a buried hazardous waste site. The integrated technology demonstration proved very successful and a summary of the technical accomplishments is presented. Upon completion of the integrated technology demonstration, cognizant program personnel participated in a lessons learned exercise. This exercise was conducted at the Simplot Decision Support Center at Idaho State University and lessons learned activity captured additional information relative to the integration of technologies for demonstration purposes. This information will be used by BWID to enhance program planning and strengthen future technology demonstrations

  1. Human exposure to unconventional natural gas development: A public health demonstration of periodic high exposure to chemical mixtures in ambient air.

    Science.gov (United States)

    Brown, David R; Lewis, Celia; Weinberger, Beth I

    2015-01-01

    Directional drilling and hydraulic fracturing of shale gas and oil bring industrial activity into close proximity to residences, schools, daycare centers and places where people spend their time. Multiple gas production sources can be sited near residences. Health care providers evaluating patient health need to know the chemicals present, the emissions from different sites and the intensity and frequency of the exposures. This research describes a hypothetical case study designed to provide a basic model that demonstrates the direct effect of weather on exposure patterns of particulate matter smaller than 2.5 microns (PM2.5) and volatile organic chemicals (VOCs). Because emissions from unconventional natural gas development (UNGD) sites are variable, a short term exposure profile is proposed that determines 6-hour assessments of emissions estimates, a time scale needed to assist physicians in the evaluation of individual exposures. The hypothetical case is based on observed conditions in shale gas development in Washington County, Pennsylvania, and on estimated emissions from facilities during gas development and production. An air exposure screening model was applied to determine the ambient concentration of VOCs and PM2.5 at different 6-hour periods of the day and night. Hourly wind speed, wind direction and cloud cover data from Pittsburgh International Airport were used to calculate the expected exposures. Fourteen months of daily observations were modeled. Higher than yearly average source terms were used to predict health impacts at periods when emissions are high. The frequency and intensity of exposures to PM2.5 and VOCs at a residence surrounded by three UNGD facilities was determined. The findings show that peak PM2.5 and VOC exposures occurred 83 times over the course of 14 months of well development. Among the stages of well development, the drilling, flaring and finishing, and gas production stages produced higher intensity exposures than the

  2. High Penetration Photovoltaic Power Electronics and Energy Management Technology Research, Development and Demonstration: Cooperative Research and Development Final Report, CRADA Number CRD-13-517

    Energy Technology Data Exchange (ETDEWEB)

    Hudgins, Andrew P. [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2018-01-25

    Advanced Energy Industries, Inc., will partner with DOE's National Renewable Energy Laboratory (NREL) to conduct research and development to demonstrate technologies that will increase the penetration of photovoltaic (PV) technologies for commercial and utility applications. Standard PV power control systems use simple control techniques that only provide real power to the grid. A focus of this partnership is to demonstrate how state of the art control and power electronic technologies can be combined to create a utility interactive control platform.

  3. Relative biological effectiveness of high energy protons for a human melanoma

    International Nuclear Information System (INIS)

    Petrovic, I.; Ristic-Fira, A.; Todorovic, D.; Valastro, I.; Cirrone, P.; Cuttone, G.

    2005-01-01

    Relative biological effectiveness (RBE) for the survival of human melanoma cells induced by high linear energy transfer (LET) protons was investigated. Exponentially growing HTB140 cells were irradiated close to the Bragg peak maximum of the 62 MeV protons, as well as with 60 Co γ-rays, over single doses, ranging from 8-24 Gy. Clonogenic survival and cell viability were assessed up to 48 h post-irradiation, therefore considered as early inactivation effects. Dose dependent cell inactivation induced by high LET protons was observed. Surviving fractions have shown great overlapping with estimated cell viability, both with the increase of dose and with prolonged cell incubation. Evaluated RBEs were higher with the rise of dose, being in the range from 2 to 3. All analyzes performed have demonstrated a very radio-resistant nature of HTB140 melanoma cells. However, high LET protons are able to inactivate these cells in a larger extent compared to the effects of γ-rays. (author)

  4. Similarity of High-Resolution Tandem Mass Spectrometry Spectra of Structurally Related Micropollutants and Transformation Products

    Science.gov (United States)

    Schollée, Jennifer E.; Schymanski, Emma L.; Stravs, Michael A.; Gulde, Rebekka; Thomaidis, Nikolaos S.; Hollender, Juliane

    2017-12-01

    High-resolution tandem mass spectrometry (HRMS2) with electrospray ionization is frequently applied to study polar organic molecules such as micropollutants. Fragmentation provides structural information to confirm structures of known compounds or propose structures of unknown compounds. Similarity of HRMS2 spectra between structurally related compounds has been suggested to facilitate identification of unknown compounds. To test this hypothesis, the similarity of reference standard HRMS2 spectra was calculated for 243 pairs of micropollutants and their structurally related transformation products (TPs); for comparison, spectral similarity was also calculated for 219 pairs of unrelated compounds. Spectra were measured on Orbitrap and QTOF mass spectrometers and similarity was calculated with the dot product. The influence of different factors on spectral similarity [e.g., normalized collision energy (NCE), merging fragments from all NCEs, and shifting fragments by the mass difference of the pair] was considered. Spectral similarity increased at higher NCEs and highest similarity scores for related pairs were obtained with merged spectra including measured fragments and shifted fragments. Removal of the monoisotopic peak was critical to reduce false positives. Using a spectral similarity score threshold of 0.52, 40% of related pairs and 0% of unrelated pairs were above this value. Structural similarity was estimated with the Tanimoto coefficient and pairs with higher structural similarity generally had higher spectral similarity. Pairs where one or both compounds contained heteroatoms such as sulfur often resulted in dissimilar spectra. This work demonstrates that HRMS2 spectral similarity may indicate structural similarity and that spectral similarity can be used in the future to screen complex samples for related compounds such as micropollutants and TPs, assisting in the prioritization of non-target compounds. [Figure not available: see fulltext.

  5. Removal of High -Concentration and Refractory Organic Matter from Diosgenin Manufacture Wastewater : a case study of a demonstration project in Hubei Province, P R China

    Science.gov (United States)

    Bao, J.; Wang, L.

    2009-12-01

    Wastewater from diosgenin manufacture is dark brown (3,500 ~4,000 times of the chroma) and acidic(pH=0.8~1.5)with high concentration of organic matter(COD=25,000~38,000 mg/L)and poor biodegradability(BOD5/COD= 0.25~0.30). It is highly toxic to biota due to the water-soluble saponin, tannins and pectin. Therefore removal of the organic matter is of great importance before the discharge of the wastewater into the environment. Here we presented a set of data from a demonstration project in Hubei province, P R China with an improved technics. This technics, focusing on the treatment of diosgenin wastewater, included hydrolytic acidification, internal electrolysis, neutralization, aerating-improved Up-flow Anaerobic Sludge Bed (UASB) and bio-contact oxidation treatment in sequence to remove the organic matter. After 60 days of starting-up, the water quality from hydrolytic acidification reactor was greatly improved. The effluent became clear, indicating the obvious removal of suspended solids in the water; the ratio of BOD/COD increased to 0.44, suggesting an significant increase of biodegradability; the content of volatile fatty acid (VFA) increased from 22.6 mmol/L to 86.8 mmol/L and the volume loading of COD reached 9.48 kg COD/(m3d). Basically at this stage the removal efficiency of COD was stabilized at 25%. Further treatment was conducted on the effluent from hydrolytic acidification reactor through the Improved UASB Reactor after the internal electrolysis and neutralization. The Improved UASB Reactor can start up at room temperature with an influent of 1,500 mg/L COD and inflow rate of 50(m3/d). Then, temperature was increased gradually to 38 oC (± 2 oC) to optimize the growth of the mesophilic anaerobes in the reactor. The content of VFA of the effluent was controlled below 8 mmol/L to guarantee the pH in the range of 6.8~7.2. After 150 days of debugging, the COD of the influent to UASB increased to 9,600 mg/L, hydraulic retaining time (HRT) was around 70 hrs

  6. High-resolution monitoring of catchment nutrient response to the end of the 2011-2012 drought in England, captured by the demonstration test catchments

    Science.gov (United States)

    Outram, F. N.; Lloyd, C.; Jonczyk, J.; Benskin, C. McW. H.; Grant, F.; Dorling, S. R.; Steele, C. J.; Collins, A. L.; Freer, J.; Haygarth, P. M.; Hiscock, K. M.; Johnes, P. J.; Lovett, A. L.

    2013-12-01

    The Demonstration Test Catchments (DTC) project is a UK Government funded initiative to test the effectiveness of on-farm mitigation measures designed to reduce agricultural pollution without compromising farm productivity. Three distinct catchments in England have been chosen to test the efficacy of mitigation measures on working farms in small tributary sub-catchments equipped with continuous water quality monitoring stations. The Hampshire Avon in the south is a mixed livestock and arable farming catchment, the River Wensum in the east is a lowland catchment with predominantly arable farming and land use in the River Eden catchment in the north-west is predominantly livestock farming. One of the many strengths of the DTC as a national research platform is that it provides the ability to investigate catchment hydrology and biogeochemical response across different landscapes and geoclimatic characteristics, with a range of differing flow behaviours, geochemistries and nutrient chemistries. Although numerous authors present studies of individual catchment responses to storms, no studies exist of multiple catchment responses to the same rainfall event captured with in situ high-resolution nutrient monitoring at a national scale. This paper brings together findings from all three DTC research groups to compare the response of the catchments to a major storm event in April 2012. This was one of the first weather fronts to track across the country following a prolonged drought period affecting much of the UK through 2011-2012, marking an unusual meteorological transition when a rapid shift from drought to flood risk occurred. The effects of the weather front on discharge and water chemistry parameters, including nitrogen species (NO3-N and NH4-N) and phosphorus fractions (total P (TP) and total reactive P (TRP)), measured at a half-hourly time step are examined. When considered in the context of one hydrological year, flow and concentration duration curves reveal that

  7. Pilot Demonstration of Technology for the Production of High Value Materials from the Ultra-Fine (PM2.5) Fraction of Coal Combustion Ash

    Energy Technology Data Exchange (ETDEWEB)

    T. L. Robl; J. G. Groppo; R. Rathbone; B. Marrs; R. Jewell

    2008-07-18

    The overall objective of this research was to determine the feasibility of recovering a very fine fraction of fly ash, that is 5 microns in diameter or less and examining the characteristics of these materials in new or at least less traditional applications. These applications included as a polymer filler or as a 'super' pozzolanic concrete additive. As part of the effort the ash from 6 power plants was investigated and characterized. This work included collection from ESP Hoppers and ponds. The ash was thoroughly characterized chemically and physically. Froth flotation was used to reduce the carbon and testing showed that flotation could effectively reduce carbon to acceptable levels (i.e. 0.5% LOI) for most of the substrates tested. in order to enable eventual use as fillers. Hydraulic classification was used in the separation of the fine ash from the coarse ash. Hydraulic classification requires the ash to be dispersed to be effective and a range of dispersants were tested for adsorption as well as sedimentation rate. A wide range of dosages were required (0.3 to 10 g/kg). In general the ponded ash required less dispersant. A model was developed for hydraulic classification. A pilot-scale hydraulic classifier was also designed and operated for the project. Product yields of up to 21% of feed solids were achieved with recoveries of <5 {micro}m particles as high as 64%. Mean particle sizes (D{sub 50}) of the ultra fine ash (UFA) products varied from 3.7 to 10 {micro}m. A patent was filed on the classifier design. A conceptual design of a Process Demonstration Unit (PDU) with a feed rate of 2 tons of raw ash feed per hour was also completed. Pozzolanic activity was determined for the UFA ashes in mortars. In general the overall strength index was excellent with values of 90% achieved in 3 days and {approx}100% in 7 days. Three types of thermoplastic polymers were evaluated with the UFA as a filler: high density polyethylene, thermoplastic elastomer and

  8. Sport-Related Structural Brain Injury: 3 Cases of Subdural Hemorrhage in American High School Football.

    Science.gov (United States)

    Yengo-Kahn, Aaron M; Gardner, Ryan M; Kuhn, Andrew W; Solomon, Gary S; Bonfield, Christopher M; Zuckerman, Scott L

    2017-10-01

    The risk of sport-related concussion (SRC) has emerged as a major public health concern. In rare instances, sport-related head injuries can be even more severe, such as subdural hemorrhage, epidural hemorrhage, or malignant cerebral edema. Unlike SRCs, sport-related structural brain injury (SRSBI) is rare, may require neurosurgical intervention, and can lead to permanent neurologic deficit or death. Data characterizing SRSBI are limited, and many have recognized the need to better understand these catastrophic brain injuries. The goal of the current series is to describe, in detail, the presentation, management, and outcomes of examples of these rare injuries. During the fall of 2015, three high school football players presented with acute subdural hemorrhages following in-game collisions and were treated at our institution within a span of 2 months. For the 2 athletes who required surgical intervention, a previous SRC was sustained within 4 weeks before the catastrophic event. One year after injury, 2 players have returned to school, though with persistent deficits. One patient remains nonverbal and wheelchair bound. None of the athletes has returned to sports. Acute subdural hemorrhage resultant from an in-game football collision is rare. The temporal proximity of the reported SRSBIs to recent SRCs emphasizes the importance of return-to-play protocols and raises questions regarding the possibility of second impact syndrome. Although epidemiologic conclusions cannot be drawn from this small sample, these cases provide a unique opportunity to demonstrate the presentation, management, and long-term outcomes of SRSBI in American high school football. Copyright © 2017 Elsevier Inc. All rights reserved.

  9. Fusion-power demonstration

    International Nuclear Information System (INIS)

    Henning, C.D.; Logan, B.G.; Carlson, G.A.; Neef, W.S.; Moir, R.W.; Campbell, R.B.; Botwin, R.; Clarkson, I.R.; Carpenter, T.J.

    1983-01-01

    As a satellite to the MARS (Mirror Advanced Reactor Study) a smaller, near-term device has been scoped, called the FPD (Fusion Power Demonstration). Envisioned as the next logical step toward a power reactor, it would advance the mirror fusion program beyond MFTF-B and provide an intermediate step toward commercial fusion power. Breakeven net electric power capability would be the goal such that no net utility power would be required to sustain the operation. A phased implementation is envisioned, with a deuterium checkout first to verify the plasma systems before significant neutron activation has occurred. Major tritium-related facilities would be installed with the second phase to produce sufficient fusion power to supply the recirculating power to maintain the neutral beams, ECRH, magnets and other auxiliary equipment

  10. Fusion power demonstration

    International Nuclear Information System (INIS)

    Henning, C.D.; Logan, B.G.

    1983-01-01

    As a satellite to the MARS (Mirror Advanced Reactor Study) a smaller, near-term device has been scoped, called the FPD (Fusion Power Demonstration). Envisioned as the next logical step toward a power reactor, it would advance the mirror fusion program beyond MFTF-B and provide an intermediate step toward commercial fusion power. Breakeven net electric power capability would be the goal such that no net utility power would be required to sustain the operation. A phased implementation is envisioned, with a deuterium checkout first to verify the plasma systems before significant neutron activation has occurred. Major tritium-related facilities would be installed with the second phase to produce sufficient fusion power to supply the recirculating power to maintain the neutral beams, ECRH, magnets and other auxiliary equipment

  11. Sex-related differences in sleep slow wave activity in major depressive disorder: a high-density EEG investigation.

    Science.gov (United States)

    Plante, David T; Landsness, Eric C; Peterson, Michael J; Goldstein, Michael R; Riedner, Brady A; Wanger, Timothy; Guokas, Jeffrey J; Tononi, Giulio; Benca, Ruth M

    2012-09-18

    Sleep disturbance plays an important role in major depressive disorder (MDD). Prior investigations have demonstrated that slow wave activity (SWA) during sleep is altered in MDD; however, results have not been consistent across studies, which may be due in part to sex-related differences in SWA and/or limited spatial resolution of spectral analyses. This study sought to characterize SWA in MDD utilizing high-density electroencephalography (hdEEG) to examine the topography of SWA across the cortex in MDD, as well as sex-related variation in SWA topography in the disorder. All-night recordings with 256 channel hdEEG were collected in 30 unipolar MDD subjects (19 women) and 30 age and sex-matched control subjects. Spectral analyses of SWA were performed to determine group differences. SWA was compared between MDD and controls, including analyses stratified by sex, using statistical non-parametric mapping to correct for multiple comparisons of topographic data. As a group, MDD subjects demonstrated significant increases in all-night SWA primarily in bilateral prefrontal channels. When stratified by sex, MDD women demonstrated global increases in SWA relative to age-matched controls that were most consistent in bilateral prefrontal regions; however, MDD men showed no significant differences relative to age-matched controls. Further analyses demonstrated increased SWA in MDD women was most prominent in the first portion of the night. Women, but not men with MDD demonstrate significant increases in SWA in multiple cortical areas relative to control subjects. Further research is warranted to investigate the role of SWA in MDD, and to clarify how increased SWA in women with MDD is related to the pathophysiology of the disorder.

  12. Relational perceptions in high school physical education: teacher- and peer-related predictors of female students’ motivation, behavioral engagement, and social anxiety

    Science.gov (United States)

    Gairns, Felicity; Whipp, Peter R.; Jackson, Ben

    2015-01-01

    Although researchers have demonstrated the importance of interpersonal processes in school-based physical education (PE), there have been calls for further studies that account for multiple relational perspectives and provide a more holistic understanding of students’ relational perceptions. Guided by principles outlined within self-determination theory and the tripartite efficacy model, our aim was to explore the ways in which students’ perceptions about their teacher and classmates directly and/or indirectly predicted motivation, anxiety, and engagement in PE. A total of 374 female high-school students reported the extent to which their teachers and classmates independently (a) engaged in relatedness-supportive behaviors, (b) satisfied their need for relatedness, and (c) were confident in their ability in PE (i.e., relation-inferred self-efficacy). Students also rated their motivation and anxiety regarding PE, and teachers provided ratings of in-class behavioral engagement for each student. Analyses demonstrated support for the predictive properties of both teacher- and peer-focused perceptions. Students largely reported more positive motivational orientations when they held favorable perceptions regarding their teacher and peers, and autonomous motivation was in turn positively related to behavioral engagement ratings. These findings offer novel insight into the network of interpersonal appraisals that directly and indirectly underpins important in-class outcomes in PE. PMID:26157404

  13. Relational perceptions in high school physical education: teacher- and peer-related predictors of female students' motivation, behavioral engagement, and social anxiety.

    Science.gov (United States)

    Gairns, Felicity; Whipp, Peter R; Jackson, Ben

    2015-01-01

    Although researchers have demonstrated the importance of interpersonal processes in school-based physical education (PE), there have been calls for further studies that account for multiple relational perspectives and provide a more holistic understanding of students' relational perceptions. Guided by principles outlined within self-determination theory and the tripartite efficacy model, our aim was to explore the ways in which students' perceptions about their teacher and classmates directly and/or indirectly predicted motivation, anxiety, and engagement in PE. A total of 374 female high-school students reported the extent to which their teachers and classmates independently (a) engaged in relatedness-supportive behaviors, (b) satisfied their need for relatedness, and (c) were confident in their ability in PE (i.e., relation-inferred self-efficacy). Students also rated their motivation and anxiety regarding PE, and teachers provided ratings of in-class behavioral engagement for each student. Analyses demonstrated support for the predictive properties of both teacher- and peer-focused perceptions. Students largely reported more positive motivational orientations when they held favorable perceptions regarding their teacher and peers, and autonomous motivation was in turn positively related to behavioral engagement ratings. These findings offer novel insight into the network of interpersonal appraisals that directly and indirectly underpins important in-class outcomes in PE.

  14. Relational perceptions in high school physical education: Teacher- and peer-related predictors of female students' motivation, behavioral engagement, and social anxiety

    Directory of Open Access Journals (Sweden)

    Felicity eGairns

    2015-06-01

    Full Text Available Although researchers have demonstrated the importance of interpersonal processes in school-based physical education (PE, there have been calls for further studies that account for multiple relational perspectives and provide a more holistic understanding of students’ relational perceptions. Guided by principles outlined within self-determination theory and the tripartite efficacy model, our aim was to explore the ways in which students’ perceptions about their teacher and classmates directly and/or indirectly predicted motivation, anxiety, and engagement in PE. A total of 374 female high-school students reported the extent to which their teachers and classmates independently (a engaged in relatedness-supportive behaviors, (b satisfied their need for relatedness, and (c were confident in their ability in PE (i.e., relation-inferred self-efficacy. Students also rated their motivation and anxiety regarding PE, and teachers provided ratings of in-class behavioral engagement for each student. Analyses demonstrated support for the predictive properties of both teacher- and peer-focused perceptions. Students largely reported more positive motivational orientations when they held favorable perceptions regarding their teacher and peers, and autonomous motivation was in turn positively related to behavioral engagement ratings. These findings offer novel insight into the network of interpersonal appraisals that directly and indirectly underpins important in-class outcomes in PE.

  15. Regulator's Workshop on The Role of Future Society and Biosphere in Demonstrating Compliance with High-Level Radioactive Waste Disposal Standards and Regulations

    Energy Technology Data Exchange (ETDEWEB)

    Avila, R. [Swedish Radiation Protection Authority, Stockholm (Sweden); Blommaert, W. [Agence Federale de Controle Nucleaire, Bruxelles (Belgium); Clark, R. [US Environmental Protection Agency (United States)] [and others

    2002-09-01

    This report summarizes the proceedings of a workshop, co-sponsored by the U.S. Environmental Protection Agency (US EPA) and the Swedish Radiation Protection Authority (SSI). The invitations to participate in the Workshop were primarily extended to authorities in countries with major nuclear waste programs involving geological disposal and using performance assessment methodology. The main objective of the Workshop was to develop a common understanding among regulators of the role of society and the biosphere in demonstrating compliance with regulations.

  16. Regulator's Workshop on The Role of Future Society and Biosphere in Demonstrating Compliance with High-Level Radioactive Waste Disposal Standards and Regulations

    International Nuclear Information System (INIS)

    Avila, R.; Blommaert, W.; Clark, R.

    2002-09-01

    This report summarizes the proceedings of a workshop, co-sponsored by the U.S. Environmental Protection Agency (US EPA) and the Swedish Radiation Protection Authority (SSI). The invitations to participate in the Workshop were primarily extended to authorities in countries with major nuclear waste programs involving geological disposal and using performance assessment methodology. The main objective of the Workshop was to develop a common understanding among regulators of the role of society and the biosphere in demonstrating compliance with regulations

  17. Is Judgement of Biotechnological Ethical Aspects Related to High School Students' Knowledge?

    Science.gov (United States)

    Črne-Hladnik, Helena; Hladnik, Aleš; Javornik, Branka; Košmelj, Katarina; Peklaj, Cirila

    2012-05-01

    Quantitative and qualitative studies of various aspects of the perception of biotechnology were conducted among 469 Slovenian high school students of average age 17 years. Our research aimed to explore relationships among students' pre-knowledge of molecular and human genetics, and their attitudes to four specific biotechnological applications. These applications-Bt corn, genetically modified (GM) salmon, somatic and germ line gene therapy (GT)-were investigated from the viewpoints of usefulness, moral acceptance and risk perception. In addition, patterns and quality of moral reasoning related to the biotechnological applications from the aspect of moral acceptability were examined. Clear gender differences were found regarding the relationship between our students' pre-knowledge of genetics and their attitudes to biotechnological applications. While females with a better genetics background expressed a higher risk perception in the case of GM salmon, their similarly well-educated male colleagues emphasized the risk associated with the use of germ line GT. With all four biotechnological applications, patterns of both rationalistic-deontological and teleological-and intuitive moral reasoning were identified. Students with poorer genetics pre-knowledge applied an intuitive pattern of moral reasoning more frequently than their peers with better pre-knowledge. A pattern of emotive reasoning was detected only in the case of GM salmon. A relatively low quality of students' moral reasoning, as demonstrated by their brief and small number of supporting justifications (explanations), show that there is a strong need for practising skills of argumentation about socio-scientific issues in Slovenian high schools on a much larger scale. The implications for future research and classroom applications are discussed.

  18. Topographic and sex-related differences in sleep spindles in major depressive disorder: a high-density EEG investigation.

    Science.gov (United States)

    Plante, D T; Goldstein, M R; Landsness, E C; Peterson, M J; Riedner, B A; Ferrarelli, F; Wanger, T; Guokas, J J; Tononi, G; Benca, R M

    2013-03-20

    Sleep spindles are believed to mediate several sleep-related functions including maintaining disconnection from the external environment during sleep, cortical development, and sleep-dependent memory consolidation. Prior studies that have examined sleep spindles in major depressive disorder (MDD) have not demonstrated consistent differences relative to control subjects, which may be due to sex-related variation and limited spatial resolution of spindle detection. Thus, this study sought to characterize sleep spindles in MDD using high-density electroencephalography (hdEEG) to examine the topography of sleep spindles across the cortex in MDD, as well as sex-related variation in spindle topography in the disorder. All-night hdEEG recordings were collected in 30 unipolar MDD participants (19 women) and 30 age and sex-matched controls. Topography of sleep spindle density, amplitude, duration, and integrated spindle activity (ISA) were assessed to determine group differences. Spindle parameters were compared between MDD and controls, including analysis stratified by sex. As a group, MDD subjects demonstrated significant increases in frontal and parietal spindle density and ISA compared to controls. When stratified by sex, MDD women demonstrated increases in frontal and parietal spindle density, amplitude, duration, and ISA; whereas MDD men demonstrated either no differences or decreases in spindle parameters. Given the number of male subjects, this study may be underpowered to detect differences in spindle parameters in male MDD participants. This study demonstrates topographic and sex-related differences in sleep spindles in MDD. Further research is warranted to investigate the role of sleep spindles and sex in the pathophysiology of MDD. Copyright © 2012 Elsevier B.V. All rights reserved.

  19. Demonstration of the trauma nurses talk tough seat belt diversion program in North Carolina reaches high-risk drivers : traffic tech.

    Science.gov (United States)

    2014-03-01

    Nationally, more than 8 of every 10 drivers wear seat belts, but : individual State belt rates vary from as high as 98% to as low as : 69%. Within individual States, rural areas often have lower rates. : Strong seat belt laws and highly visible enfor...

  20. Smart Grid Demonstration Project

    Energy Technology Data Exchange (ETDEWEB)

    Miller, Craig [National Rural Electric Cooperative Association, Arlington, VA (United States); Carroll, Paul [National Rural Electric Cooperative Association, Arlington, VA (United States); Bell, Abigail [National Rural Electric Cooperative Association, Arlington, VA (United States)

    2015-03-11

    The National Rural Electric Cooperative Association (NRECA) organized the NRECA-U.S. Department of Energy (DOE) Smart Grid Demonstration Project (DE-OE0000222) to install and study a broad range of advanced smart grid technologies in a demonstration that spanned 23 electric cooperatives in 12 states. More than 205,444 pieces of electronic equipment and more than 100,000 minor items (bracket, labels, mounting hardware, fiber optic cable, etc.) were installed to upgrade and enhance the efficiency, reliability, and resiliency of the power networks at the participating co-ops. The objective of this project was to build a path for other electric utilities, and particularly electrical cooperatives, to adopt emerging smart grid technology when it can improve utility operations, thus advancing the co-ops’ familiarity and comfort with such technology. Specifically, the project executed multiple subprojects employing a range of emerging smart grid technologies to test their cost-effectiveness and, where the technology demonstrated value, provided case studies that will enable other electric utilities—particularly electric cooperatives— to use these technologies. NRECA structured the project according to the following three areas: Demonstration of smart grid technology; Advancement of standards to enable the interoperability of components; and Improvement of grid cyber security. We termed these three areas Technology Deployment Study, Interoperability, and Cyber Security. Although the deployment of technology and studying the demonstration projects at coops accounted for the largest portion of the project budget by far, we see our accomplishments in each of the areas as critical to advancing the smart grid. All project deliverables have been published. Technology Deployment Study: The deliverable was a set of 11 single-topic technical reports in areas related to the listed technologies. Each of these reports has already been submitted to DOE, distributed to co-ops, and

  1. A Comprehensive General Chemistry Demonstration

    Science.gov (United States)

    Sweeder, Ryan D.; Jeffery, Kathleen A.

    2013-01-01

    This article describes the use of a comprehensive demonstration suitable for a high school or first-year undergraduate introductory chemistry class. The demonstration involves placing a burning candle in a container adjacent to a beaker containing a basic solution with indicator. After adding a lid, the candle will extinguish and the produced…

  2. Biodiesel Mass Transit Demonstration

    Science.gov (United States)

    2010-04-01

    The Biodiesel Mass Transit Demonstration report is intended for mass transit decision makers and fleet managers considering biodiesel use. This is the final report for the demonstration project implemented by the National Biodiesel Board under a gran...

  3. Authoring Effective Demonstrations

    National Research Council Canada - National Science Library

    Fu, Dan; Jensen, Randy; Salas, Eduardo; Rosen, Michael A; Ramachandran, Sowmya; Upshaw, Christin L; Hinkelman, Elizabeth; Lampton, Don

    2007-01-01

    ... or human role-players for each training event. We report our ongoing efforts to (1) research the nature and purpose of demonstration, articulating guidelines for effective demonstration within a training context, and (2...

  4. Polarized Light Corridor Demonstrations.

    Science.gov (United States)

    Davies, G. R.

    1990-01-01

    Eleven demonstrations of light polarization are presented. Each includes a brief description of the apparatus and the effect demonstrated. Illustrated are strain patterns, reflection, scattering, the Faraday Effect, interference, double refraction, the polarizing microscope, and optical activity. (CW)

  5. Peer Relations and Peer Deviance as Predictors of Reactive and Proactive Aggression among High School Girls

    Science.gov (United States)

    Uz Bas, Asli; Öz Soysal, Fatma Selda

    2016-01-01

    This study aimed to investigate associations between reactive and proactive aggression and peer relations and peer deviance among high school girls. A total of 442 high school students participated in this study. Reactive-Proactive Aggression Questionnaire, the Peer Relations Scale, and the Peer Deviance Scale were used to collect data. Results…

  6. Mass and metallicity scaling relations of high-redshift star-forming galaxies selected by GRBs

    DEFF Research Database (Denmark)

    Arabsalmani, M.; Møller, P.; Perley, D.~A.

    2018-01-01

    -metallicity relation of the general population. It is hard to decide whether this relatively small offset is due to systematic effects or the intrinsic nature of GRB hosts. We also investigate the possibility of using absorption-line metallicity measurements of GRB hosts to study the mass-metallicity relation at high...

  7. Strategy Guideline: Demonstration Home

    Energy Technology Data Exchange (ETDEWEB)

    Savage, C.; Hunt, A.

    2012-12-01

    This guideline will provide a general overview of the different kinds of demonstration home projects, a basic understanding of the different roles and responsibilities involved in the successful completion of a demonstration home, and an introduction into some of the lessons learned from actual demonstration home projects. Also, this guideline will specifically look at the communication methods employed during demonstration home projects. And lastly, we will focus on how to best create a communication plan for including an energy efficient message in a demonstration home project and carry that message to successful completion.

  8. Strategy Guideline. Demonstration Home

    Energy Technology Data Exchange (ETDEWEB)

    Hunt, A.; Savage, C.

    2012-12-01

    This guideline will provide a general overview of the different kinds of demonstration home projects, a basic understanding of the different roles and responsibilities involved in the successful completion of a demonstration home, and an introduction into some of the lessons learned from actual demonstration home projects. Also, this guideline will specifically look at the communication methods employed during demonstration home projects. And lastly, we will focus on how to best create a communication plan for including an energy efficient message in a demonstration home project and carry that message to successful completion.

  9. Health-Related Quality of Life in Children with High-Functioning Autism

    Science.gov (United States)

    Potvin, Marie-Christine; Snider, Laurie; Prelock, Patricia A.; Wood-Dauphinee, Sharon; Kehayia, Eva

    2015-01-01

    The health-related quality of life of school-aged children with high-functioning autism is poorly understood. The objectives of this study were to compare the health-related quality of life of children with high-functioning autism to that of typically developing peers and to compare child-self and parent-proxy reports of health-related quality of…

  10. Demonstration of AlGaN/GaN metal-oxide-semiconductor high-electron-mobility transistors with silicon-oxy-nitride as the gate insulator

    International Nuclear Information System (INIS)

    Balachander, K.; Arulkumaran, S.; Egawa, T.; Sano, Y.; Baskar, K.

    2005-01-01

    AlGaN/GaN metal-oxide-semiconductor high-electron-mobility transistors (MOSHEMTs) were fabricated with plasma enhanced chemical vapor deposited silicon oxy-nitride (SiON) as an insulating layer. The compositions of SiON thin films were confirmed using X-ray photoelectron spectroscopy. The fabricated MOSHEMTs exhibited a very high saturation current density of 1.1 A/mm coupled with high positive operational gate voltage up to +7 V. The MOSHEMTs also exhibited four orders of low gate leakage current and high forward-on voltage when compared with the conventional HEMTs. The drain current collapse using gate pulse measurements showed only a negligible difference in the saturation current density revealing the drastic improvement in passivation of the surface states due to the high quality of dielectric thin films deposited. Thus, based on the improved direct-current operation, SiON can be considered to be a potential gate oxide comparable with other dielectric insulators

  11. Development and Demonstration of a High Efficiency, Rapid Heating, Low NOx Alternative to Conventional Heating of Round Steel Shapes, Steel Substrate (Strip) and Coil Box Transfer Bars

    Energy Technology Data Exchange (ETDEWEB)

    Kurek, Harry; Wagner, John

    2010-01-25

    Direct Flame Impingement involves the use of an array of very high-velocity flame jets impinging on a work piece to rapidly heat the work piece. The predominant mode of heat transfer is convection. Because of the locally high rate of heat transfer at the surface of the work piece, the refractory walls and exhaust gases of a DFI furnace are significantly cooler than in conventional radiant heating furnaces, resulting in high thermal efficiency and low NOx emissions. A DFI furnace is composed of a successive arrangement of heating modules through or by which the work piece is conveyed, and can be configured for square, round, flat, and curved metal shapes (e.g., billets, tubes, flat bars, and coiled bars) in single- or multi-stranded applications.

  12. Mapping of Junior High School Students’ Social Relation Problem and the Needed Assisting Model

    OpenAIRE

    Arbin Janu Setiyowati; Marthen Pali; Bambang Budi Wiyono; Triyono

    2017-01-01

    This research aims to describe Junior High School students’ social relation problem and the needed assisting model. This research used descriptive design with survey method. The subjects of this research were Junior High School students in the three cities in East Java. This research used purposive sampling as well. The data was collected by using questionnaire. The data analysis was conducted descriptively. This research found that Junior High School students’ social relation problems includ...

  13. Material-related issues at high-power and high-energy ion beam facilities

    CERN Document Server

    Bender, M.; Tomut, M.; Trautmann, C.

    2015-01-01

    When solids are exposed to energetic ions (MeV-GeV), their physical and chemical structure can be severely modified. The change is governed by ultrafast dynamical processes starting from the deposition of large energy densities, electronic excitation and ionization processes, and finally damage creation in the atomic lattice system. In many materials, each projectile creates a cylindrical track with a few nanometers in diameter and up to many μm in length. To study and monitor the creation of damage, the GSI irradiation facility dedicated to materials science provides different in-situ and on-line techniques such as high resolution microscopy, X-ray diffraction, optical absorption spectroscopy, thermal imaging and residual gas analysis. The irradiation experiments can be performed under various gas atmospheres and under cryogenic or elevated temperature.

  14. Highly tissue specific expression of Sphinx supports its male courtship related role in Drosophila melanogaster.

    Science.gov (United States)

    Chen, Ying; Dai, Hongzheng; Chen, Sidi; Zhang, Luoying; Long, Manyuan

    2011-04-26

    Sphinx is a lineage-specific non-coding RNA gene involved in regulating courtship behavior in Drosophila melanogaster. The 5' flanking region of the gene is conserved across Drosophila species, with the proximal 300 bp being conserved out to D. virilis and a further 600 bp region being conserved amongst the melanogaster subgroup (D. melanogaster, D. simulans, D. sechellia, D. yakuba, and D. erecta). Using a green fluorescence protein transformation system, we demonstrated that a 253 bp region of the highly conserved segment was sufficient to drive sphinx expression in male accessory gland. GFP signals were also observed in brain, wing hairs and leg bristles. An additional ∼800 bp upstream region was able to enhance expression specifically in proboscis, suggesting the existence of enhancer elements. Using anti-GFP staining, we identified putative sphinx expression signal in the brain antennal lobe and inner antennocerebral tract, suggesting that sphinx might be involved in olfactory neuron mediated regulation of male courtship behavior. Whole genome expression profiling of the sphinx knockout mutation identified significant up-regulated gene categories related to accessory gland protein function and odor perception, suggesting sphinx might be a negative regulator of its target genes.

  15. Highly tissue specific expression of Sphinx supports its male courtship related role in Drosophila melanogaster.

    Directory of Open Access Journals (Sweden)

    Ying Chen

    2011-04-01

    Full Text Available Sphinx is a lineage-specific non-coding RNA gene involved in regulating courtship behavior in Drosophila melanogaster. The 5' flanking region of the gene is conserved across Drosophila species, with the proximal 300 bp being conserved out to D. virilis and a further 600 bp region being conserved amongst the melanogaster subgroup (D. melanogaster, D. simulans, D. sechellia, D. yakuba, and D. erecta. Using a green fluorescence protein transformation system, we demonstrated that a 253 bp region of the highly conserved segment was sufficient to drive sphinx expression in male accessory gland. GFP signals were also observed in brain, wing hairs and leg bristles. An additional ∼800 bp upstream region was able to enhance expression specifically in proboscis, suggesting the existence of enhancer elements. Using anti-GFP staining, we identified putative sphinx expression signal in the brain antennal lobe and inner antennocerebral tract, suggesting that sphinx might be involved in olfactory neuron mediated regulation of male courtship behavior. Whole genome expression profiling of the sphinx knockout mutation identified significant up-regulated gene categories related to accessory gland protein function and odor perception, suggesting sphinx might be a negative regulator of its target genes.

  16. Delirium and High Creatine Kinase and Myoglobin Levels Related to Synthetic Cannabinoid Withdrawal

    Directory of Open Access Journals (Sweden)

    Ahmet Bulent Yazici

    2017-01-01

    Full Text Available Synthetic cannabinoids (SCs are included in a group of drugs called new psychoactive substances. Effects of SCs on the central nervous system are similar to other cannabinoids, but 2–100 times more potent than marijuana. Thus, addiction and withdrawal symptoms are more severe than natural cannabinoids. Withdrawal symptoms of SCs were reported in the literature previously. But there is no report about SC withdrawal delirium and its treatment. Several studies reported that agonists of CB1 receptors play a role in GABA and glutamatergic neurotransmission, which is similar to the effects of alcohol on GABA and glutamatergic receptors. Previous studies on alcohol delirium cases suggested that elevated creatine kinase (CK can be a marker of progress. This study reports delirium and high serum CK levels related to SC withdrawal and offers a treatment with benzodiazepine for them. We described two cases treated in our inpatient clinic about SC withdrawal with increase of serum CK level and other laboratory parameters. One of them demonstrated delirium symptoms and the other did not with early rapid treatment.

  17. Studies Related to Chemical Mechanisms of Gas Formation in Hanford High-Level Nuclear Wastes

    International Nuclear Information System (INIS)

    Barefield, E. Kent; Liotta, Charles L.; Neumann, Henry M.

    2002-01-01

    The objective of this work is to develop a more detailed mechanistic understanding of the thermal reactions that lead to gas production in certain high-level waste storage tanks at the Hanford, Washington site. Prediction of the combustion hazard for these wastes and engineering parameters for waste processing depend upon both a knowledge of the composition of stored wastes and the changes that they undergo as a result of thermal and radiolytic decomposition. Since 1980 when Delagard first demonstrated that gas production (H2and N2O initially, later N2 and NH3)in the affected tanks was related to oxidative degradation of metal complexants present in the waste, periodic attempts have been made to develop detailed mechanisms by which the gases were formed. These studies have resulted in the postulation of a series of reactions that account for many of the observed products, but which involve several reactions for which there is limited, or no, precedent. For example, Al(OH)4 has been postulated to function as a Lewis acid to catalyze the reaction of nitrite ion with the metal complexants, NO is proposed as an intermediate, and the ratios of gaseous products may be a result of the partitioning of NO between two or more reactions. These reactions and intermediates have been the focus of this project since its inception in 1996

  18. A highly pathogenic avian influenza virus H5N1 with 2009 pandemic H1N1 internal genes demonstrated increased replication and transmission in pigs

    Science.gov (United States)

    This study investigated the pathogenicity and transmissibility of a reverse-genetics derived highly pathogenic avian influenza (HPAI) H5N1 influenza A virus (IAV), A/Iraq/775/06, and a reassortant virus comprised of the HA and NA from A/Iraq/775/06 and the internal genes of a 2009 pandemic H1N1, A/N...

  19. Learning to Learn: An Analysis of Early Learning Behaviours Demonstrated by Young Deaf/Hard-of-Hearing Children with High/Low Mathematics Ability

    Science.gov (United States)

    Pagliaro, Claudia M.; Kritzer, Karen L.

    2010-01-01

    Using a multiple case-study design, this study compares the early learning behaviours of young deaf/hard-of-hearing (d/hh) children with high/low mathematics ability (as defined by test score on the Test of Early Mathematics Ability-3). Children's simultaneous use of multiple learning behaviours was also examined as were contributing adult…

  20. Teaching High School Physical Education According to National Standards: The 6 Verbs of Success--Demonstrate, Understand, Participate, Achieve, Exhibit and Value

    Science.gov (United States)

    Bert, Greg

    2010-01-01

    The six national content standards from NASPE define what a student should know and be able to do as a result of a high quality physical education program. The "NASPE SIX" serve as a North Star to guide teachers as they prepare and implement programs. Simply stated, the NASPE Standards for Physical Education are all about six simple…

  1. Technology Research, Integration, and Demonstration (TRIAD) Program, Delivery Order 0013: High Strain Rate Tension Testing of Titanium 6-2-4-2S at Temperature

    Science.gov (United States)

    2016-06-01

    ASSIGNED DISTRIBUTION STATEMENT. *//Signature// //Signature// BRIAN T. GOCKEL MICHAEL S. BROWN, Chief Program Manager Hypersonic Sciences Branch...Washington Headquarters Services, Directorate for Information Operations and Reports (0704-0188), 1215 Jefferson Davis Highway, Suite 1204, Arlington...STATEMENT A: Approved for public release. Distribution is unlimited. Figure 3. Room-Temperature High-Speed DIC Tensile Setup A slack adapter was

  2. HPV type-related chromosomal profiles in high-grade cervical intraepithelial neoplasia

    Directory of Open Access Journals (Sweden)

    Bierkens Mariska

    2012-01-01

    Full Text Available Abstract Background The development of cervical cancer and its high-grade precursor lesions (Cervical Intraepithelial Neoplasia grade 2/3 [CIN2/3] result from a persistent infection with high-risk human papillomavirus (hrHPV types and the accumulation of (epigenetic host cell aberrations. Epidemiological studies have demonstrated variable CIN2/3 and cancer risks between different hrHPV types. Recent genomic profiling studies revealed substantial heterogeneity in the chromosomal aberrations detected in morphologically indistinguishable CIN2/3 suggestive of varying cancer risk. The current study aimed to investigate whether CIN2/3 with different hrHPV types vary with respect to their chromosomal profiles, both in terms of the number of aberrations and chromosomal loci affected. Methods Chromosomal profiles were determined of 43 p16INK4a-immunopositive CIN2/3 of women with long-term hrHPV infection (≥ 5 years. Sixteen lesions harboured HPV16, 3 HPV18, 14 HPV31, 1 HPV33, 4 HPV45, 1 HPV51, 2 HPV52 and 2 HPV58. Results Unsupervised hierarchical clustering analysis of the chromosomal profiles revealed two major clusters, characterised by either few or multiple chromosomal aberrations, respectively. A majority of 87.5% of lesions with HPV16 were in the cluster with relatively few aberrations, whereas no such unbalanced distribution was seen for lesions harbouring other hrHPV types. Analysis of the two most prevalent types (HPV16 and HPV31 in this data set revealed a three-fold increase in the number of losses in lesions with HPV31 compared to HPV16-positive lesions. In particular, losses at chromosomes 2q, 4p, 4q, 6p, 6q, 8q & 17p and gain at 1p & 1q were significantly more frequent in HPV31-positive lesions (FDR Conclusions Chromosomal aberrations in CIN2/3 are at least in part related to the hrHPV type present. The relatively low number of chromosomal aberrations observed in HPV16-positive CIN2/3 suggests that the development of these lesions is

  3. Safety of high speed ground transportation systems: X2000 US demonstration vehicle dynamics trials, preliminary test report. Report for October 1992-January 1993

    Energy Technology Data Exchange (ETDEWEB)

    Whitten, B.T.; Kesler, J.K.

    1993-01-01

    The report documents the procedures, events, and results of vehicle dynamic tests carried out on the ASEA-Brown Boveri (ABB) X2000 tilt body trainset in the US between October 1992 and January 1993. These tests, sponsored by Amtrak and supported by the FRA, were conducted to assess the suitability of the X2000 trainset for safe operation at elevated cant deficiencies and speeds in Amtrak's Northeast Corridor under existing track conditions in a revenue service demonstration. The report describes the safety criteria against which the performance of the X2000 test train was examined, the instrumentation used, the test locations, and the track conditions. Preliminary results are presented from tests conducted on Amtrak lines between Philadelphia and Harrisburg, PA, and between Washington DC and New York NY, in which cant deficiencies of 12.5 inches and speeds of 154 mph were reached in a safe and controlled manner. The significance of the results is discussed, and preliminary conclusions and recommendations are presented.

  4. Manufacturing Demonstration Facility (MDF)

    Data.gov (United States)

    Federal Laboratory Consortium — The U.S. Department of Energy Manufacturing Demonstration Facility (MDF) at Oak Ridge National Laboratory (ORNL) provides a collaborative, shared infrastructure to...

  5. Demonstrating the use of high-volume electronic medical claims data to monitor local and regional influenza activity in the US.

    Directory of Open Access Journals (Sweden)

    Cécile Viboud

    Full Text Available Fine-grained influenza surveillance data are lacking in the US, hampering our ability to monitor disease spread at a local scale. Here we evaluate the performances of high-volume electronic medical claims data to assess local and regional influenza activity.We used electronic medical claims data compiled by IMS Health in 480 US locations to create weekly regional influenza-like-illness (ILI time series during 2003-2010. IMS Health captured 62% of US outpatient visits in 2009. We studied the performances of IMS-ILI indicators against reference influenza surveillance datasets, including CDC-ILI outpatient and laboratory-confirmed influenza data. We estimated correlation in weekly incidences, peak timing and seasonal intensity across datasets, stratified by 10 regions and four age groups (<5, 5-29, 30-59, and 60+ years. To test IMS-Health performances at the city level, we compared IMS-ILI indicators to syndromic surveillance data for New York City. We also used control data on laboratory-confirmed Respiratory Syncytial Virus (RSV activity to test the specificity of IMS-ILI for influenza surveillance.Regional IMS-ILI indicators were highly synchronous with CDC's reference influenza surveillance data (Pearson correlation coefficients rho≥0.89; range across regions, 0.80-0.97, P<0.001. Seasonal intensity estimates were weakly correlated across datasets in all age data (rho≤0.52, moderately correlated among adults (rho≥0.64 and uncorrelated among school-age children. IMS-ILI indicators were more correlated with reference influenza data than control RSV indicators (rho = 0.93 with influenza v. rho = 0.33 with RSV, P<0.05. City-level IMS-ILI indicators were highly consistent with reference syndromic data (rho≥0.86.Medical claims-based ILI indicators accurately capture weekly fluctuations in influenza activity in all US regions during inter-pandemic and pandemic seasons, and can be broken down by age groups and fine geographical areas

  6. Demonstration of Multi-Gbps Data Rates at Ka-Band Using Software-Defined Modem and Broadband High Power Amplifier for Space Communications

    Science.gov (United States)

    Simons, Rainee N.; Wintucky, Edwin G.; Landon, David G.; Sun, Jun Y.; Winn, James S.; Laraway, Stephen; McIntire, William K.; Metz, John L.; Smith, Francis J.

    2011-01-01

    The paper presents the first ever research and experimental results regarding the combination of a software-defined multi-Gbps modem and a broadband high power space amplifier when tested with an extended form of the industry standard DVB-S2 and LDPC rate 9/10 FEC codec. The modem supports waveforms including QPSK, 8-PSK, 16-APSK, 32-APSK, 64-APSK, and 128-QAM. The broadband high power amplifier is a space qualified traveling-wave tube (TWT), which has a passband greater than 3 GHz at 33 GHz, output power of 200 W and efficiency greater than 60 percent. The modem and the TWTA together enabled an unprecedented data rate at 20 Gbps with low BER of 10(exp -9). The presented results include a plot of the received waveform constellation, BER vs. E(sub b)/N(sub 0) and implementation loss for each of the modulation types tested. The above results when included in an RF link budget analysis show that NASA s payload data rate can be increased by at least an order of magnitude (greater than 10X) over current state-of-practice, limited only by the spacecraft EIRP, ground receiver G/T, range, and available spectrum or bandwidth.

  7. Perfectionism in High-Ability Students: Relational Precursors and Influences on Achievement Motivation

    Science.gov (United States)

    Speirs Neumeister, Kristie L.; Finch, Holmes

    2006-01-01

    The purpose of the present study was to create and test a model that (a) illustrated variables influencing the development of perfectionism, and (b) demonstrated how different types of perfectionism may influence the achievement goals of high-ability students. Using a multiple groups path analysis, the researchers found that parenting style was…

  8. Kinesthetic Transverse Wave Demonstration

    Science.gov (United States)

    Pantidos, Panagiotis; Patapis, Stamatis

    2005-09-01

    This is a variation on the String and Sticky Tape demonstration "The Wave Game," suggested by Ron Edge. A group of students stand side by side, each one holding a card chest high with both hands. The teacher cues the first student to begin raising and lowering his card. When he starts lowering his card, the next student begins to raise his. As succeeding students move their cards up and down, a wave such as that shown in the figure is produced. To facilitate the process, students' motions were synchronized with the ticks of a metronome (without such synchronization it was nearly impossible to generate a satisfactory wave). Our waves typically had a frequency of about 1 Hz and a wavelength of around 3 m. We videotaped the activity so that the students could analyze the motions. The (17-year-old) students had not received any prior instruction regarding wave motion and did not know beforehand the nature of the exercise they were about to carry out. During the activity they were asked what a transverse wave is. Most of them quickly realized, without teacher input, that while the wave propagated horizontally, the only motion of the transmitting medium (them) was vertical. They located the equilibrium points of the oscillations, the crests and troughs of the waves, and identified the wavelength. The teacher defined for them the period of the oscillations of the motion of a card to be the total time for one cycle. The students measured this time and then several asserted that it was the same as the wave period. Knowing the length of the waves and the number of waves per second, the next step can easily be to find the wave speed.

  9. Optimization of a micro-scale, high throughput process development tool and the demonstration of comparable process performance and product quality with biopharmaceutical manufacturing processes.

    Science.gov (United States)

    Evans, Steven T; Stewart, Kevin D; Afdahl, Chris; Patel, Rohan; Newell, Kelcy J

    2017-07-14

    In this paper, we discuss the optimization and implementation of a high throughput process development (HTPD) tool that utilizes commercially available micro-liter sized column technology for the purification of multiple clinically significant monoclonal antibodies. Chromatographic profiles generated using this optimized tool are shown to overlay with comparable profiles from the conventional bench-scale and clinical manufacturing scale. Further, all product quality attributes measured are comparable across scales for the mAb purifications. In addition to supporting chromatography process development efforts (e.g., optimization screening), comparable product quality results at all scales makes this tool is an appropriate scale model to enable purification and product quality comparisons of HTPD bioreactors conditions. The ability to perform up to 8 chromatography purifications in parallel with reduced material requirements per run creates opportunities for gathering more process knowledge in less time. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.

  10. Examining Relational Engagement across the Transition to High Schools in Three US High Schools Reformed to Improve Relationship Quality

    Science.gov (United States)

    Davis, Heather A.; Chang, Mei-Lin; Andrzejewski, Carey E.; Poirier, Ryan R.

    2014-01-01

    The purpose of this study was to examine changes in students' relational engagement across the transition to high school in three schools reformed to improve the quality of student-teacher relationships. In order to analyze this data we employed latent growth curve (LGC) modeling techniques (n = 637). We ran three LGC models on three…

  11. Obese individuals with more components of the metabolic syndrome and/or prediabetes demonstrate decreased activation of reward-related brain centers in response to food cues in both the fed and fasting states: a preliminary fMRI study.

    Science.gov (United States)

    Farr, O M; Mantzoros, C S

    2017-03-01

    It remains unknown whether obese individuals with more components of the metabolic syndrome and/or prediabetes demonstrate altered activation of brain centers in response to food cues. We examined obese individuals with prediabetes (n=26) vs obese individuals without prediabetes (n=11) using fMRI. We also performed regression analyses on the basis of the number of MetS components per subject. Obese individuals with prediabetes have decreased activation of the reward-related putamen in the fasting state and decreased activation of the salience- and reward-related insula after eating. Obese individuals with more components of MetS demonstrate decreased activation of the putamen while fasting. All these activations remain significant when corrected for BMI, waist circumference (WC), HbA1c and gender. Decreased activation in the reward-related central nervous system areas among the obese is more pronounced in subjects with prediabetes and MetS. Prospective studies are needed to quantify their contributions to the development of prediabetes/MetS and to study whether they may predispose to the exacerbation of obesity and the development of comorbidities over time.

  12. Emotional reactions to alcohol-related words: Differences between low- and high-risk drinkers.

    Science.gov (United States)

    Gantiva, Carlos; Delgado, Rafael; Romo-González, Tania

    2015-11-01

    Research that has examined responses to alcohol-related words in drinkers has mostly linked such responses to memory, attentional, and perceptual bias. However, studies of emotional processing in alcoholics have not received much attention. The main goal of the present study was to identify the features and differences of emotional responses to alcohol-related words in low- and high-risk drinkers. A total of 149 low-risk drinkers and 125 high-risk drinkers evaluated five alcohol-related words and 15 words from the Affective Norms for English Words in the dimensions of valence, arousal, and dominance using the Self-Assessment Manikin. The results indicated that high-risk drinkers evaluated alcohol-related words as more appetitive and arousing. These results, together with findings in the attention and memory research literature, suggest that alcohol-related words can serve as conditioned cues in alcohol consumption. Copyright © 2015 Elsevier Ltd. All rights reserved.

  13. High-grade renal injuries are often isolated in sports-related trauma

    OpenAIRE

    Patel, Darshan P.; Redshaw, Jeffrey D.; Breyer, Benjamin N.; Smith, Thomas G.; Erickson, Bradley A.; Majercik, Sarah D.; Gaither, Thomas W.; Craig, James R.; Gardner, Scott; Presson, Angela P.; Zhang, Chong; Hotaling, James M.; Brant, William O.; Myers, Jeremy B.

    2015-01-01

    © 2015 Elsevier Ltd. All rights reserved. Introduction: Most high-grade renal injuries (American Association for Surgery of Trauma (AAST) grades III-V) result from motor vehicle collisions associated with numerous concomitant injuries. Sports-related blunt renal injury tends to have a different mechanism, a solitary blow to the flank. We hypothesized that high-grade renal injury is often isolated in sports-related renal trauma. Material and methods: We identified patients with AAST grades III...

  14. Preparation and demonstration of poly(dopamine)-triggered attapulgite-anchored polyurethane as a high-performance rod-like elastomer to reinforce soy protein-isolated composites

    Science.gov (United States)

    Zhao, Shujun; Wen, Yingying; Wang, Zhong; Kang, Haijiao; Li, Jianzhang; Zhang, Shifeng; Ji, Yong

    2018-06-01

    Nanophase modification is an effective path to improve composite properties, however, it remains a great challenge to increase the mechanical strength of the modified materials without sacrificing elongation and toughness. This study presents a novel and efficient design for interface anchoring of a waterborne polyurethane (WPU) elastomer with attapulgite (ATP) triggered by poly(dopamine) (PDA) formation due to self-polymerization of the dopamine moieties. The WPU-PDA-ATP (WDA) rod-like elastomer served as an active enhancer for a soy protein isolate (SPI)-based composite to facilitate multiple interactions between SPI and the elastomer. As expected, the PDA layer was coated onto ATP, inducing the nanofiller to successfully anchor onto the WPU elastomer, as confirmed by solid-state 13C NMR, XPS, and ATR-FTIR results. Compared with the control SPI-based film, the tensile strength and toughness increased by 145.6% and 118.3% respectively by introducing WDA rod-like elastomer. The water resistance and thermal stability of the prepared SPI composites were also favorable. The proposed approach represents an efficient way to utilize high-performance elastomer in biobased materials to concurrently enhance strength and toughness.

  15. A decade of telerobotics in rehabilitation: Demonstrated utility blocked by the high cost of manipulation and the complexity of the user interface

    Science.gov (United States)

    Leifer, Larry; Michalowski, Stefan; Vanderloos, Machiel

    1991-01-01

    The Stanford/VA Interactive Robotics Laboratory set out in 1978 to test the hypothesis that industrial robotics technology could be applied to serve the manipulation needs of severely impaired individuals. Five generations of hardware, three generations of system software, and over 125 experimental subjects later, we believe that genuine utility is achievable. The experience includes development of over 65 task applications using voiced command, joystick control, natural language command and 3D object designation technology. A brief foray into virtual environments, using flight simulator technology, was instructive. If reality and virtuality come for comparable prices, you cannot beat reality. A detailed review of assistive robot anatomy and the performance specifications needed to achieve cost/beneficial utility will be used to support discussion of the future of rehabilitation telerobotics. Poised on the threshold of commercial viability, but constrained by the high cost of technically adequate manipulators, this worthy application domain flounders temporarily. In the long run, it will be the user interface that governs utility.

  16. Simultaneous production of l-lactic acid with high optical activity and a soil amendment with food waste that demonstrates plant growth promoting activity.

    Science.gov (United States)

    Kitpreechavanich, Vichien; Hayami, Arisa; Talek, Anfal; Chin, Clament Fui Seung; Tashiro, Yukihiro; Sakai, Kenji

    2016-07-01

    A unique method to produce highly optically-active l-lactic acid and soil amendments that promote plant growth from food waste was proposed. Three Bacillus strains Bacillus subtilis KBKU21, B. subtilis N3-9 and Bacillus coagulans T27, were used. Strain KBKU21 accumulated 36.9 g/L l-lactic acid with 95.7% optical activity and 98.2% l-lactic acid selectivity when fermented at 43°C for 84 h in a model kitchen refuse (MKR) medium. Residual precipitate fraction (anaerobically-fermented MKR (AFM) compost) analysis revealed 4.60%, 0.70% and 0.75% of nitrogen (as N), phosphorous (as P2O5), and potassium (as K2O), respectively. Additionally, the carbon to nitrogen ratio decreased from 13.3 to 10.6. AFM compost with KBKU21 promoted plant growth parameters, including leaf length, plant height and fresh weight of Brassica rapa (Komatsuna), than that by chemical fertilizers or commercial compost. The concept provides an incentive for the complete recycling of food waste, contributing towards a sustainable production system. Copyright © 2016 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

  17. Health-related quality of life in children with high-functioning autism.

    Science.gov (United States)

    Potvin, Marie-Christine; Snider, Laurie; Prelock, Patricia A; Wood-Dauphinee, Sharon; Kehayia, Eva

    2015-01-01

    The health-related quality of life of school-aged children with high-functioning autism is poorly understood. The objectives of this study were to compare the health-related quality of life of children with high-functioning autism to that of typically developing peers and to compare child-self and parent-proxy reports of health-related quality of life of children. A cross-sectional study of children with high-functioning autism (n = 30) and peers (n = 31) was conducted using the Pediatric Quality of Life Inventory 4.0 Generic Core Scales. Children with high-functioning autism had significantly poorer health-related quality of life than peers whether reported by themselves (p children and parental scores suggested variance in points of view. This study specifically investigated health-related quality of life in children with high-functioning autism as compared to a sample of peers, from the child's perspective. It strengthens earlier findings that children with high-functioning autism experience poorer health-related quality of life than those without this disorder and points to the importance of clinicians working with families to identify areas in a child's life that promote or hinder their sense of well-being. © The Author(s) 2013.

  18. Senior High School Students' Errors on the Use of Relative Words

    Science.gov (United States)

    Bao, Xiaoli

    2015-01-01

    Relative clause is one of the most important language points in College English Examination. Teachers have been attaching great importance to the teaching of relative clause, but the outcomes are not satisfactory. Based on Error Analysis theory, this article aims to explore the reasons why senior high school students find it difficult to choose…

  19. Misconceptions of High School Students Related to the Conceptions of Absolutism and Constitutionalism in History Courses

    Science.gov (United States)

    Bal, Mehmet Suat

    2011-01-01

    The goal of this study is to analyze the 10th grade high school students' misconceptions related to the sense of ruling in the Ottoman State during the absolutist and constitutional periods and to investigate the causes of these misconceptions. The data were collected through eight open-ended questions related to the concepts of absolutism and…

  20. High School Students' Time Management Skills in Relation to Research Anxiety

    Science.gov (United States)

    Akcoltekin, Alpturk

    2015-01-01

    This study aimed to determine the opinions of high school students relating to time management and present a correlation of their time management skills with demographic variables, as well as examining the relation between their level of research anxiety and time management skills. The study group composed 270 12th-grade students (127 males and…

  1. Verbal Memory Deficits in Relation to Organization Strategy in High- and Low-Functioning Autistic Children

    Science.gov (United States)

    Cheung, Mei-chun; Chan, Agnes S.; Sze, Sophia L.; Leung, Winnie W.; To, Cho Yee

    2010-01-01

    The present study examined the verbal memory profile and its relation to organizational strategies in high-functioning (Hi-AUT) and low-functioning (Lo-AUT) children with autism. Twenty-two Hi-AUT and 16 Lo-AUT, and 22 age-, gender- and handedness-matched normal children (NC) were required to remember a list of semantically related words for…

  2. High-Performance Classrooms for Women? Applying a Relational Frame to Management/Organizational Behavior Courses.

    Science.gov (United States)

    Buttner, E. Holly

    2002-01-01

    Attributes of relational theory, based on women's development, include preventive connecting, mutual empowering, achieving, and team building. These attributes are compatible with the practices of high performance work organizations. Relational practices should be integrated into management and organizational behavior courses. (Contains 53…

  3. Innovative technology demonstration

    International Nuclear Information System (INIS)

    Anderson, D.B.; Luttrell, S.P.; Hartley, J.N.; Hinchee, R.

    1992-04-01

    The Innovative Technology Demonstration (ITD) program at Tinker Air Force Base (TAFB), Oklahoma City, Oklahoma, will demonstrate the overall utility and effectiveness of innovative technologies for site characterization, monitoring, and remediation of selected contaminated test sites. The current demonstration test sites include a CERCLA site on the NPL list, located under a building (Building 3001) that houses a large active industrial complex used for rebuilding military aircraft, and a site beneath and surrounding an abandoned underground tank vault used for storage of jet fuels and solvents. The site under Building 3001 (the NW Test Site) is contaminated with TCE and Cr +6 ; the site with the fuel storage vault (the SW Tanks Site) is contaminated with fuels, BTEX and TCE. These sites and others have been identified for cleanup under the Air Force's Installation Restoration Program (IRP). This document describes the demonstrations that have been conducted or are planned for the TAFB

  4. Laser Communications Relay Demonstration

    Data.gov (United States)

    National Aeronautics and Space Administration — LCRD is a minimum two year flight demonstration in geosynchronous Earth orbit to advance optical communications technology toward infusion into Deep Space and Near...

  5. Spacecraft Fire Safety Demonstration

    Data.gov (United States)

    National Aeronautics and Space Administration — The objective of the Spacecraft Fire Safety Demonstration project is to develop and conduct large-scale fire safety experiments on an International Space Station...

  6. Banks-Casher-type relation for the BCS gap at high density

    OpenAIRE

    Kanazawa, Takuya; Wettig, Tilo; Yamamoto, Naoki

    2012-01-01

    We derive a new Banks-Casher-type relation which relates the density of complex Dirac eigenvalues at the origin to the BCS gap of quarks at high density. Our relation is applicable to QCD and QCD-like theories without a sign problem, such as two-color QCD and adjoint QCD with baryon chemical potential, and QCD with isospin chemical potential. It provides us with a method to measure the BCS gap through the Dirac spectrum on the lattice.

  7. Scintiscanning demonstration of thymoma

    International Nuclear Information System (INIS)

    Yuzuriha, Hideki; Morimoto, Masami; Inokawa, Koichi; Hikita, Hitoshi; Iida, Futoshi; Nakanishi, Fumiko; Sone, Shunsuke

    1986-01-01

    Thymus scintigraphy was performed using 201 Tl-chloride, 67 Ga-citrate and 75 Se-selenomethionine on 30 thymoma patients with or without myasthenia gravis. Mass negativity was observed in 6 out of 17 (35.3 per cent) and 3 out of 13 cases (23.1 per cent), respectively. A rate of 70 per cent (21 cases out of 30) of mass positivity was observed by thymus scan using 201 Tl. With regard to the relation between thymus scan and cell type, 201 Tl-scan exhibited a high rate of mass positivity, regardless of the cell type while the 75 Se-scan showed a trend toward mass positivity in epithelial cell predominant cases. With 201 Tl, mass positivity was observed when the CPM/g ratio for tumors and blood exceeded 3.0. This trend can serve as an index for the suitability of supplementary chemo- and radiotherapies, as well as for prognosis in cases of relapse, and in those for whom excision was not complete. (author)

  8. Education Payload Operation - Demonstrations

    Science.gov (United States)

    Keil, Matthew

    2009-01-01

    Education Payload Operation - Demonstrations (EPO-Demos) are recorded video education demonstrations performed on the International Space Station (ISS) by crewmembers using hardware already onboard the ISS. EPO-Demos are videotaped, edited, and used to enhance existing NASA education resources and programs for educators and students in grades K-12. EPO-Demos are designed to support the NASA mission to inspire the next generation of explorers.

  9. Development of Probabilistic Safety Assessment with respect to the first demonstration nuclear power plant of high temperature gas cooled reactor in China

    International Nuclear Information System (INIS)

    Tong Jiejuan; Zhao Jun; Liu Tao; Xue Dazhi

    2012-01-01

    Due to the unique concept of HTR-PM (High Temperature Gas Cooled Reactor-Pebble Bed Module) design, Chinese nuclear authority has anticipated that HTR-PM will bring challenge to the present regulation. The pilot use of PSA (Probabilistic Safety Assessment) during HTR-PM design and safety review is deemed to be the necessary and efficient tool to tackle the problem, and is actively encouraged as indicated in the authority's specific policy statement on HTR-PM project. The paper summarizes the policy statement to set up the base of PSA development and application activities. The up-to-date status of HTR-PM PSA development and the risk-informed application activities are introduced in this paper as the follow-up response to the policy statement. For open discussion, the paper hereafter puts forward several technical issues which have been encountered during HTR-PM PSA development. Since HTR-PM PSA development experience has the general conclusion that many of the PSA elements can be and have been implemented successfully by the traditional PSA techniques, only the issues which extra innovative efforts may be needed are highlighted in this paper. They are safety goal and risk metrics, PSA modeling framework for the non-water reactors, passive system reliability evaluation, initiating events frequencies and component reliability data estimation techniques for the new reactors and so on. The paper presents the way in which the encountered technical issues were or will be solved, although the proposed way may not be the ultimate best solution. The paper intends to express the standpoint that although the PSA of new reactor has the inherent weakness due to the insufficient information and larger data uncertainty, the problem of component reliability data is much less severe than people have conceived. The unique design conception and functional features of the reactors can influence the results more significantly than the component reliability data. What we are benefited

  10. Buried Waste Integrated Demonstration

    International Nuclear Information System (INIS)

    1994-03-01

    The Buried Waste Integrated Demonstration (BWID) supports the applied research, development, demonstration, and evaluation of a suite of advanced technologies that offer promising solutions to the problems associated with the remediation of buried waste. BWID addresses the difficult remediation problems associated with DOE complex-wide buried waste, particularly transuranic (TRU) contaminated buried waste. BWID has implemented a systems approach to the development and demonstration of technologies that will characterize, retrieve, treat, and dispose of DOE buried wastes. This approach encompasses the entire remediation process from characterization to post-monitoring. The development and demonstration of the technology is predicated on how a technology fits into the total remediation process. To address all of these technological issues, BWID has enlisted scientific expertise of individuals and groups from within the DOE Complex, as well as experts from universities and private industry. The BWID mission is to support development and demonstration of a suite of technologies that, when integrated with commercially-available technologies, forms a comprehensive, remediation system for the effective and efficient remediation of buried waste throughout the DOE Complex. BWID will evaluate and validate demonstrated technologies and transfer this information and equipment to private industry to support the Office of Environmental Restoration (ER), Office of Waste Management (WM), and Office of Facility Transition (FT) remediation planning and implementation activities

  11. Citation Rate of Highly-Cited Papers in 100 Kinesiology-Related Journals

    Science.gov (United States)

    Knudson, Duane

    2015-01-01

    This study extended previous research on several citation-based bibliometric variables for highly cited articles in a large (N = 100) number of journals related to Kinesiology. Total citations and citation rate of the 30 most highly cited articles in each journal were identified by searchers of "Google Scholar (GS)". Other major…

  12. Special Theory of Relativity in South Korean High School Textbooks and New Teaching Guidelines

    Science.gov (United States)

    Gim, Jinyeong

    2016-01-01

    South Korean high school students are being taught Einstein's Special Theory of Relativity. In this article, I examine the portrayal of this theory in South Korean high school physics textbooks and discuss an alternative method used to solve the analyzed problems. This examination of how these South Korean textbooks present this theory has…

  13. Work-related fatigue: the specific case of highly educated women in the Netherlands

    NARCIS (Netherlands)

    Verdonk, P.; Hooftman, W.E.; Veldhoven, M.J.P.M. van; Boelens, L.R.M.; Koppes, L.L.J.

    2009-01-01

    Purpose: This study aims to establish the prevalence of high work-related fatigue (need for recovery, NFR) among employees and to explain group differences categorized by gender, age, and education. The study particularly aims to clarify prevalence and explanatory factors in highly educated women.

  14. Patients with hepatic breast cancer metastases demonstrate highly specific profiles of matrix metalloproteinases MMP-2 and MMP-9 after SIRT treatment as compared to other primary and secondary liver tumours

    International Nuclear Information System (INIS)

    Golubnitschaja, Olga; Yeghiazaryan, Kristina; Stricker, Helena; Trog, Daniela; Schild, Hans H.; Berliner, Leonard

    2016-01-01

    Patients with primary and metastatic liver malignancies represent a highly heterogeneous patient pool characterised by some of the shortest life expectancies amongst oncology patients. Investigation and better understanding of liver malignancies is an emerging field which requires high-quality multidisciplinary research and collaboration. A study of 158 patients with primary hepatic carcinomas and secondary liver metastases, altogether 15 cancer types of different origin, who underwent selective internal radiation therapy (SIRT) with Yttrium 90 or transarterial chemoembolisation, was undertaken in an effort to detect distinguishing features with respect to activity profiles of both blood matrix metalloproteinase (MMP-2 and MMP-9). Noteworthy, stratification of all hepatic cancer groups with respect to MMP-2 and MMP-9 activities revealed characteristic patterns specifically in patients with hepatic breast cancer metastases who had undergone SIRT. In contrast to all other groups, these patients demonstrated well-consolidated profiles of both MMPs, reflecting a common feature, namely an immediate and durable increase of their activity after the SIRT treatment. Although the total number of patients in the breast cancer group is relatively small (15 patients), since increased activities of MMP-2 and MMP-9 are well known prognostic factors for poor outcomes of oncologic patients, the significance and clear group-specificity (from 15 ones investigated here) of this previously unanticipated finding requires particular attention and further investigations. Particularly important is to determine, whether this increase of the metalloproteinase activity was provoked by SIRT, as well as whether special selection criteria are required for patients with breast cancer metastases to the liver who are being considered for SIRT. It is recommended that a more focused, multidisciplinary and large-scaled investigations of the possible adverse effects of SIRT in patients with advanced

  15. [Analysis of highly cited papers related to malaria in Chinese journals from 2006 to 2013].

    Science.gov (United States)

    Yao, Deng; Jin-Yu, Mo; Jian, Li

    2016-01-25

    To analyze the highly cited malaria papers published in Chinese journals from 2006 to 2013, so as to provide the evidence for formulating the plan of selecting topics to the journal editors. The published articles related to malaria included in CNKI and Wanfang medical network from 2006 to 2013 were collected, and the highly cited papers were selected according to the citation frequency calculated by Price's formula. Then the characteristics of the highly cited papers were analyzed. From 2006 to 2013, a total of 1 976 published papers related to malaria were searched in Chinese journals and 98 papers of them were selected as highly cited papers. In the highly cited papers, 18 papers were published in China Tropical Medicine , and 16 and 15 papers were published in Chinese Journal of Parasitology and Parasitic Diseases and Chinese Journal of Schistosomiasis Control , respectively; and original articles accounted for 42.86%; the first authors of these papers were from 44 institutions, and 40.91% of them were from centers for disease control and prevention (CDCs); a percentage of 22.45% of the highly cited papers received fund programs, and most of them were national or provincial funds. The research hotspots were focused on the epidemiology and control, and epidemic situation of malaria. The highly cited papers related to malaria are mainly from CDCs and research institutions, and the related journals could use this information to chose topics and solicit contributions to improve their influence.

  16. Demonstration of Cauchy: Understanding Algebraic

    Directory of Open Access Journals (Sweden)

    T.L. Costa

    2012-11-01

    Full Text Available ABSTRACT: In this study we present some considerations about the End of Course Work undergraduate Full Degree in Mathematics / UFMT, drafted in 2011, and by taking title "A story about Cauchy and Euler's theorem on polyhedra" that gave birth to our research project Master of Education, begun in 2012, on the approaches of Euler's theorem on polyhedra in mathematics textbooks. At work in 2011 presented some considerations about the history of Euler's theorem for polyhedra which focus the demonstration presented by Cauchy (1789-1857, who tries to generalize it, relying on assumptions not observable in Euclidean geometry. Therefore, we seek the accessible literature on the history of mathematics; relate some aspects of the demonstration Cauchy with historical events on the development of mathematics in the nineteenth century, which allowed the acceptance of such a demonstration by mathematicians of his time.Keywords: History of Mathematics. Euler's Theorem on Polyhedra. Demonstration of Cauchy.

  17. Learning From Demonstration?

    DEFF Research Database (Denmark)

    Koch, Christian; Bertelsen, Niels Haldor

    2014-01-01

    Demonstration projects are often used in the building sector to provide a basis for using new processes and/or products. The climate change agenda implies that construction is not only required to deliver value for the customer, cost reductions and efficiency but also sustainable buildings....... This paper reports on an early demonstration project, the Building of a passive house dormitory in the Central Region of Denmark in 2006-2009. The project was supposed to deliver value, lean design, prefabrication, quality in sustainability, certification according to German standards for passive houses......, and micro combined heat and power using hydrogen. Using sociological and business economic theories of innovation, the paper discusses how early movers of innovation tend to obtain only partial success when demonstrating their products and often feel obstructed by minor details. The empirical work...

  18. Solar renovation demonstration projects

    Energy Technology Data Exchange (ETDEWEB)

    Bruun Joergensen, O [ed.

    1998-10-01

    In the framework of the IEA SHC Programme, a Task on building renovation was initiated, `Task 20, Solar Energy in Building Renovation`. In a part of the task, Subtask C `Design of Solar Renovation Projects`, different solar renovation demonstration projects were developed. The objective of Subtask C was to demonstrate the application of advanced solar renovation concepts on real buildings. This report documents 16 different solar renovation demonstration projects including the design processes of the projects. The projects include the renovation of houses, schools, laboratories, and factories. Several solar techniques were used: building integrated solar collectors, glazed balconies, ventilated solar walls, transparent insulation, second skin facades, daylight elements and photovoltaic systems. These techniques are used in several simple as well as more complex system designs. (au)

  19. Biodenitrification demonstration test report

    International Nuclear Information System (INIS)

    Benear, A.K.; Murray, S.J.; Lahoda, E.J.; Leslie, J.W.; Patton, J.B.; Menako, C.R.

    1987-08-01

    A two-column biodenitrification (BDN) facility was constructed at the Feed Materials Production Center (FMPC) in 1985 and 1986 to test the feasibility of biological treatment for industrial nitrate-bearing waste water generated at FMPC. This demonstration facility comprises one-half of the proposed four-column production facility. A demonstration test was conducted over a four month period in 1987. The results indicate the proposed BDN production facility can process FMPC industrial wastewater in a continuous manner while maintaining an effluent that will consistently meet the proposed NPDES limits for combined nitrate nitrogen (NO 3 -N) and nitrite nitrogen (NO 2 -N). The proposed NPDES limits are 62 kg/day average and 124 kg/day maximum. These limits were proportioned to determine that the two-column demonstration facility should meet the limits of 31 kg/day average and 62 kg/day maximum

  20. Distributed picture compilation demonstration

    Science.gov (United States)

    Alexander, Richard; Anderson, John; Leal, Jeff; Mullin, David; Nicholson, David; Watson, Graham

    2004-08-01

    A physical demonstration of distributed surveillance and tracking is described. The demonstration environment is an outdoor car park overlooked by a system of four rooftop cameras. The cameras extract moving objects from the scene, and these objects are tracked in a decentralized way, over a real communication network, using the information form of the standard Kalman filter. Each node therefore has timely access to the complete global picture and because there is no single point of failure in the system, it is robust. The demonstration system and its main components are described here, with an emphasis on some of the lessons we have learned as a result of applying a corpus of distributed data fusion theory and algorithms in practice. Initial results are presented and future plans to scale up the network are also outlined.

  1. Photovoltaic demonstration projects

    Energy Technology Data Exchange (ETDEWEB)

    Gillett, W B; Hacker, R J; Kaut, W [eds.

    1991-01-01

    This book, the proceedings of the fourth PV-Contractors' Meeting organized by the Commission of the European Communities, Directorate-General for Energy, held at Brussels on 21 and 22 November 1989, provides an overview of the photovoltaic demonstration projects which have been supported in the framework of the Energy Demonstration Program since 1983. It includes reports by each of the contractors who submitted proposals in 1983, 1984, 1985 and 1986, describing progress with their projects. Summaries of the discussions held at the meeting, which included contractors whose projects were submitted in 1987, are also presented. The different technologies which are being demonstrated concern the modules, the cabling of the array, structure design, storage strategy and power conditioning. The various applications include desalination, communications, dairy farms, water pumping, and warning systems. Papers have been processed separately for inclusion on the data base.

  2. Electric vehicle demonstration

    Energy Technology Data Exchange (ETDEWEB)

    Ouellet, M. [National Centre for Advanced Transportation, Saint-Jerome, PQ (Canada)

    2010-07-01

    The desirable characteristics of Canadian projects that demonstrate vehicle use in real-world operation and the appropriate mechanism to collect and disseminate the monitoring data were discussed in this presentation. The scope of the project was on passenger cars and light duty trucks operating in plug-in electric vehicle (PHEV) or battery electric vehicle modes. The presentation also discussed the funding, stakeholders involved, Canadian travel pattern analysis, regulatory framework, current and recent electric vehicle demonstration projects, and project guidelines. It was concluded that some demonstration project activities may have been duplicated as communication between the proponents was insufficient. It was recommended that data monitoring using automatic data logging with minimum reliance on logbooks and other user entry should be emphasized. figs.

  3. High-grade renal injuries are often isolated in sports-related trauma.

    Science.gov (United States)

    Patel, Darshan P; Redshaw, Jeffrey D; Breyer, Benjamin N; Smith, Thomas G; Erickson, Bradley A; Majercik, Sarah D; Gaither, Thomas W; Craig, James R; Gardner, Scott; Presson, Angela P; Zhang, Chong; Hotaling, James M; Brant, William O; Myers, Jeremy B

    2015-07-01

    Most high-grade renal injuries (American Association for Surgery of Trauma (AAST) grades III-V) result from motor vehicle collisions associated with numerous concomitant injuries. Sports-related blunt renal injury tends to have a different mechanism, a solitary blow to the flank. We hypothesized that high-grade renal injury is often isolated in sports-related renal trauma. We identified patients with AAST grades III-V blunt renal injuries from four level 1 trauma centres across the United States between 1/2005 and 1/2014. Patients were divided into "Sport" or "Non-sport" related groups. Outcomes included rates of hypotension (systolic blood pressure 110bpm), concomitant abdominal injury, and procedural/surgical intervention between sports and non-sports related injury. 320 patients met study criteria. 18% (59) were sports-related injuries with the most common mechanisms being skiing, snowboarding and contact sports (25%, 25%, and 24%, respectively). Median age was 24 years for sports and 30 years for non-sports related renal injuries (p=0.049). Males were more commonly involved in sports related injuries (85% vs. 72%, p=0.011). Median injury severity score was lower for sports related injuries (10 vs. 27, pinjury scale scores. Sports related trauma was more likely to be isolated without other significant injury (69% vs. 39% (psports and non-sports renal injuries (p=0.30). Sports injuries had lower transfusion (7% vs. 47%, psports vs. 18% non-sports, p=0.95). High-grade sports-related blunt renal trauma is more likely to occur in isolation without other abdominal or thoracic injuries and clinicians must have a high suspicion of renal injury with significant blows to the flank during sports activities. Copyright © 2015 Elsevier Ltd. All rights reserved.

  4. Innovative technology demonstrations

    International Nuclear Information System (INIS)

    Anderson, D.B.; Luttrell, S.P.; Hartley, J.N.

    1992-08-01

    Environmental Management Operations (EMO) is conducting an Innovative Technology Demonstration Program for Tinker Air Force Base (TAFB). Several innovative technologies are being demonstrated to address specific problems associated with remediating two contaminated test sites at the base. Cone penetrometer testing (CPT) is a form of testing that can rapidly characterize a site. This technology was selected to evaluate its applicability in the tight clay soils and consolidated sandstone sediments found at TAFB. Directionally drilled horizontal wells was selected as a method that may be effective in accessing contamination beneath Building 3001 without disrupting the mission of the building, and in enhancing the extraction of contamination both in ground water and in soil. A soil gas extraction (SGE) demonstration, also known as soil vapor extraction, will evaluate the effectiveness of SGE in remediating fuels and TCE contamination contained in the tight clay soil formations surrounding the abandoned underground fuel storage vault located at the SW Tanks Site. In situ sensors have recently received much acclaim as a technology that can be effective in remediating hazardous waste sites. Sensors can be useful for determining real-time, in situ contaminant concentrations during the remediation process for performance monitoring and in providing feedback for controlling the remediation process. Following the SGE demonstration, the SGE system and SW Tanks test site will be modified to demonstrate bioremediation as an effective means of degrading the remaining contaminants in situ. The bioremediation demonstration will evaluate a bioventing process in which the naturally occurring consortium of soil bacteria will be stimulated to aerobically degrade soil contaminants, including fuel and TCE, in situ

  5. Innovative technology demonstrations

    International Nuclear Information System (INIS)

    Anderson, D.B.; Hartley, J.N.; Luttrell, S.P.

    1992-04-01

    Currently, several innovative technologies are being demonstrated at Tinker Air Force Base (TAFB) to address specific problems associated with remediating two contaminated test sites at the base. Cone penetrometer testing (CPT) is a form of testing that can rapidly characterize a site. This technology was selected to evaluate its applicability in the tight clay soils and consolidated sandstone sediments found at TAFB. Directionally drilled horizontal wells have been successfully installed at the US Department of Energy's (DOE) Savannah River Site to test new methods of in situ remediation of soils and ground water. This emerging technology was selected as a method that may be effective in accessing contamination beneath Building 3001 without disrupting the mission of the building, and in enhancing the extraction of contamination both in ground water and in soil. A soil gas extraction (SGE) demonstration, also known as soil vapor extraction, will evaluate the effectiveness of SGE in remediating fuels and TCE contamination contained in the tight clay soil formations surrounding the abandoned underground fuel storage vault located at the SW Tanks Site. In situ sensors have recently received much acclaim as a technology that can be effective in remediating hazardous waste sites. Sensors can be useful for determining real-time, in situ contaminant concentrations during the remediation process for performance monitoring and in providing feedback for controlling the remediation process. A demonstration of two in situ sensor systems capable of providing real-time data on contamination levels will be conducted and evaluated concurrently with the SGE demonstration activities. Following the SGE demonstration, the SGE system and SW Tanks test site will be modified to demonstrate bioremediation as an effective means of degrading the remaining contaminants in situ

  6. Photovoltaic demonstration projects 2

    Energy Technology Data Exchange (ETDEWEB)

    Gillett, W B; Hacker, R J [Halcrow (William) and Partners, Swindon (UK); Kaut, W [eds.

    1989-01-01

    This book, the proceedings of the third Photovoltaic Contractors' Meeting organised by the Commission of the European Communities, Directorate-General for Energy provides an overview of the photovoltaic demonstration projects which have been supported by the Energy Directorate of the Commission of the European Communities since 1983. It includes reports by each of the contractors who submitted proposals in 1983, 1984 and 1985, describing progress with their projects. The different technologies which are being demonstrated concern the modules, the cabling of the array, structure design, storage strategy and power conditioning. The various applications include powering of houses, villages, recreation centres, water desalination, communications, dairy farms, water pumping and warning systems. (author).

  7. Good-to-Great Superintendents: An Examination of Jim Collins' Good-to-Great Level Five Leadership Attributes as Demonstrated by the Leadership Behaviors of Superintendents of High-Performing California Public Single-School Districts

    Science.gov (United States)

    Brown, James D.

    2010-01-01

    Purpose: The purpose of this study was to examine Collins' good-to-great Level Five leadership attributes, as demonstrated by the leadership behaviors of superintendents of high-performing California public single-school districts. Methodology: The researcher used a case study design to conduct this study. Personal interviews were conducted in…

  8. High Performance Auxiliary Power Unit Technology Demonstrator.

    Science.gov (United States)

    1980-12-01

    aft bearings 1.13 P3 - Power producer CDP 1.14 DPHE - Lube pressure drop at heat exchanger 1.15 POFP - Load airflow orifice pressure 1.16 DPOFP - Load...P𔃽I -PSI G PEBL -PSIG P2 -PS.IG DPHE -PID POFP -F Iu 0. 022±_ 77. 3478 6o5. 6 4±4 ±8L-. 4852 19. 51-17.4 DPOFP -PSID Ni -,. N2-i -RPM NSATM -FPM...28. 0250 83. 3505 29. 861 1:9. 7680 PGi -PSIG PEBL -PSIG P3 -PSIG DPHE -PSID POFP -PSIG 0. 0100 77. 9199 72.4862 17. 25 ±19. 4122 1= DPOFP -PSID NI

  9. Actinide Separation Demonstration Facility, Tarapur

    International Nuclear Information System (INIS)

    Vishwaraj, I.

    2017-01-01

    Partitioning of minor actinide from high level waste could have a substantial impact in lowering the radio toxicity associated with high level waste as well as it will reduce the burden on geological repository. In Indian context, the partitioned minor actinide could be routed into the fast breeder reactor systems scheduled for commissioning in the near period. The technological breakthrough in solvent development has catalyzed the partitioning programme in India, leading to the setting up and hot commissioning of the Actinide Separation Demonstration Facility (ASDF) at BARC, Tarapur. The engineering scale Actinide Separation Demonstration Facility (ASDF) has been retrofitted in an available radiological hot cell situated adjacent to the Advanced Vitrification Facility (AVS). This location advantage ensures an uninterrupted supply of high-level waste and facilitates the vitrification of the high-level waste after separation of minor actinides

  10. Nasal variation in relation to high-altitude adaptations among Tibetans and Andeans.

    Science.gov (United States)

    Butaric, Lauren N; Klocke, Ross P

    2018-05-01

    High-altitude (>2500 m) populations face several pressures, including hypoxia and cold-dry air, resulting in greater respiratory demand to obtain more oxygen and condition inspired air. While cardiovascular and pulmonary adaptations to high-altitude hypoxia have been extensively studied, adaptations of upper-respiratory structures, e.g., nasal cavity, remain untested. This study investigates whether nasal morphology presents adaptations to hypoxic (larger noses) and/or cold-dry (tall/narrow noses) conditions among high-altitude samples. CT scans of two high- and four low-altitude samples from diverse climates were collected (n = 130): high-altitude Tibetans and Peruvians; low-altitude Peruvians, Southern Chinese (temperate), Mongolian-Buriats (cold-dry), and Southeast Asians (hot-wet). Facial and nasal distances were calculated from 3D landmarks placed on digitally-modeled crania. Temperature, precipitation, and barometric pressure data were also obtained. Principal components analysis and analyses of variance primarily indicate size-related differences among the cold-dry (Mongolian-Buriats) and hot-wet (Southeast Asians) adapted groups. Two-block partial least squares (PLS) analysis show weak relationships between size-standardized nasal dimensions and environmental variables. However, among PLS1 (85.90% of covariance), Tibetans display relatively larger nasal cavities related to lower temperatures and barometric pressure; regression analyses also indicate high-altitude Tibetans possess relatively larger internal nasal breadths and heights for their facial size. Overall, nasal differences relate to climate among the cold-dry and hot-wet groups. Specific nasal adaptations were not identified among either Peruvian group, perhaps due to their relatively recent migration history and population structure. However, high-altitude Tibetans seem to exhibit a compromise in nasal morphology, serving in increased oxygen uptake, and air-conditioning processes. © 2018

  11. PHARUS ASAR demonstrator

    NARCIS (Netherlands)

    Smith, A.J.E.; Bree, R.J.P. van; Calkoen, C.J.; Dekker, R.J.; Otten, M.P.G.; Rossum, W.L. van

    2001-01-01

    PHARUS is a polarimetric phased array C-band Synthetic Aperture Radar (SAR), designed and built for airborne use. Advanced SAR (ASAR) data in image and alternating polarization mode have been simulated with PHARUS to demonstrate the use of Envisat for a number of typical SAR applications that are

  12. Demonstrating the Gas Laws.

    Science.gov (United States)

    Holko, David A.

    1982-01-01

    Presents a complete computer program demonstrating the relationship between volume/pressure for Boyle's Law, volume/temperature for Charles' Law, and volume/moles of gas for Avagadro's Law. The programing reinforces students' application of gas laws and equates a simulated moving piston to theoretical values derived using the ideal gas law.…

  13. Astronomy LITE Demonstrations

    Science.gov (United States)

    Brecher, Kenneth

    2006-12-01

    Project LITE (Light Inquiry Through Experiments) is a materials, software, and curriculum development project. It focuses on light, optics, color and visual perception. According to two recent surveys of college astronomy faculty members, these are among the topics most often included in the large introductory astronomy courses. The project has aimed largely at the design and implementation of hands-on experiences for students. However, it has also included the development of lecture demonstrations that employ novel light sources and materials. In this presentation, we will show some of our new lecture demonstrations concerning geometrical and physical optics, fluorescence, phosphorescence and polarization. We have developed over 200 Flash and Java applets that can be used either by teachers in lecture settings or by students at home. They are all posted on the web at http://lite.bu.edu. For either purpose they can be downloaded directly to the user's computer or run off line. In lecture demonstrations, some of these applets can be used to control the light emitted by video projectors to produce physical effects in materials (e.g. fluorescence). Other applets can be used, for example, to demonstrate that the human percept of color does not have a simple relationship with the physical frequency of the stimulating source of light. Project LITE is supported by Grant #DUE-0125992 from the NSF Division of Undergraduate Education.

  14. A Magnetic Circuit Demonstration.

    Science.gov (United States)

    Vanderkooy, John; Lowe, June

    1995-01-01

    Presents a demonstration designed to illustrate Faraday's, Ampere's, and Lenz's laws and to reinforce the concepts through the analysis of a two-loop magnetic circuit. Can be made dramatic and challenging for sophisticated students but is suitable for an introductory course in electricity and magnetism. (JRH)

  15. Identifying practice-related factors for high-volume prescribers of antibiotics in Danish general practice

    DEFF Research Database (Denmark)

    Aabenhus, Rune; Siersma, Volkert Dirk; Sandholdt, Håkon

    2017-01-01

    practice-related factors driving high antibiotic prescribing rates. Results: We included 98% of general practices in Denmark (n = 1962) and identified a 10% group of high prescribers who accounted for 15% of total antibiotic prescriptions and 18% of critically important antibiotic prescriptions. Once case...... prescriptions issued over the phone compared with all antibiotic prescriptions; and a high number of consultations per 1000 patients. We also found that a low number of consultations per 1000 patients was associated with a reduced likelihood of being a high prescriber of antibiotics. Conclusions: An apparent...

  16. THE RELATION OF HIGH-PERFORMANCE WORK SYSTEMS WITH EMPLOYEE INVOLVEMENT

    Directory of Open Access Journals (Sweden)

    Bilal AFSAR

    2010-01-01

    Full Text Available The basic aim of high performance work systems is to enable employees to exercise decision making, leading to flexibility, innovation, improvement and skill sharing. By facilitating the development of high performance work systems we help organizations make continuous improvement a way of life.The notion of a high-performance work system (HPWS constitutes a claim that there exists a system of work practices for core workers in an organisation that leads in some way to superior performance. This article will discuss the relation that HPWS has with the improvement of firms’ performance and high involvement of the employees.

  17. High Dietary Protein Intake and Protein-Related Acid Load on Bone Health.

    Science.gov (United States)

    Cao, Jay J

    2017-12-01

    Consumption of high-protein diets is increasingly popular due to the benefits of protein on preserving lean mass and controlling appetite and satiety. The paper is to review recent clinical research assessing dietary protein on calcium metabolism and bone health. Epidemiological studies show that long-term, high-protein intake is positively associated with bone mineral density and reduced risk of bone fracture incidence. Short-term interventional studies demonstrate that a high-protein diet does not negatively affect calcium homeostasis. Existing evidence supports that the negative effects of the acid load of protein on urinary calcium excretion are offset by the beneficial skeletal effects of high-protein intake. Future research should focus on the role and the degree of contribution of other dietary and physiological factors, such as intake of fruits and vegetables, in reducing the acid load and further enhancing the anabolic effects of protein on the musculoskeletal system.

  18. Comparative analysis of Ligusticum chuanxiong and related umbelliferous medicinal plants by high performance liquid chromatography-electrospray ionization mass spectrometry.

    Science.gov (United States)

    Yi, Tao; Leung, Kelvin Sze-Yin; Lu, Guang-Hua; Zhang, Hao

    2007-04-01

    A highly precise and accurate method, based on high performance liquid chromatography-electrospray ionization mass spectrometry (HPLC-ESI-MS), was developed for the qualitative and quantitative comparison of the main constituents in the rhizome of Ligusticum chuanxiong (LC) and three related umbelliferous medicinal plants. A comprehensive validation of the developed method was conducted, and the method was highly sensitive, reproducible and accurate. The unique properties of the present method were validated by analyzing 20 related herbal samples including 5 LC samples, 5 Cnidium officinale samples (CO), 5 Angelica sinensis samples (AS) and 5 Angelica acutiloba samples (AA). Twelve compounds including phenolic constituents, alkylphthalides and phthalide dimers were identified by online ESI-MS and by comparison with literature data and standard compounds, and six of them were quantified by HPLC-DAD simultaneously. The results demonstrated that identical compound types were identified as the main constituents of LC, CO, AS and AA herbs. The results also support the alternative application of these medicinal plants in Chinese and Japanese folk medicines. In the present study, it was found that the variation in the abundance of senkyunolide A was significant in these related herbs; it is therefore feasible to choose senkyunolide A as a characteristic compound for quality evaluation and chemical authentication of these herbs.

  19. Improving asthma-related health outcomes among low-income, multiethnic, school-aged children: results of a demonstration project that combined continuous quality improvement and community health worker strategies.

    Science.gov (United States)

    Fox, Patrick; Porter, Patricia G; Lob, Sibylle H; Boer, Jennifer Holloman; Rocha, David A; Adelson, Joel W

    2007-10-01

    The purpose of this work was to improve asthma-related health outcomes in an ethnically and geographically disparate population of economically disadvantaged school-aged children by using a team-based approach using continuous quality improvement and community health workers. A demonstration project was conducted with 7 community clinics treating approximately 3000 children with asthma 5 to 18 years of age. The overall clinic population with asthma was assessed for care-process changes through random cross-sectional chart reviews at baseline and 24 months (N = 560). A subset of patients with either moderate or severe persistent asthma or poorly controlled asthma (N = 405) was followed longitudinally for specific asthma-related clinical outcomes, satisfaction with care, and confidence managing asthma by family interview at baseline and at 12 or 24 months. Patient-centered and care-process outcomes included patient/parent assessment of quality of care and confidence in self-management, asthma action plan review, and documentation of guideline-based indicators of quality of care. Direct clinical outcomes included daytime and nighttime symptoms, use of rescue medications, acute care and emergency department visits, hospitalizations, and missed school days. Each clinic site's degree of adherence to the intervention model was evaluated and ranked to examine the correlation between model adherence and outcomes. Cross-sectional data showed clinic-wide improvements in the documentation of asthma severity, review of action plans, health services use, and asthma symptoms. At follow-up in the longitudinal sample, fewer patients reported acute visits, emergency department visits, hospitalizations, frequent daytime and nighttime symptoms, and missed school days compared with baseline. More patients reported excellent or very good quality of care and confidence in asthma self-management. Linear regression analysis of the clinical sites' model adherence ranks against site

  20. High Accuracy Acoustic Relative Humidity Measurement inDuct Flow with Air

    Directory of Open Access Journals (Sweden)

    Cees van der Geld

    2010-08-01

    Full Text Available An acoustic relative humidity sensor for air-steam mixtures in duct flow is designed and tested. Theory, construction, calibration, considerations on dynamic response and results are presented. The measurement device is capable of measuring line averaged values of gas velocity, temperature and relative humidity (RH instantaneously, by applying two ultrasonic transducers and an array of four temperature sensors. Measurement ranges are: gas velocity of 0–12 m/s with an error of ±0.13 m/s, temperature 0–100 °C with an error of ±0.07 °C and relative humidity 0–100% with accuracy better than 2 % RH above 50 °C. Main advantage over conventional humidity sensors is the high sensitivity at high RH at temperatures exceeding 50 °C, with accuracy increasing with increasing temperature. The sensors are non-intrusive and resist highly humid environments.

  1. High accuracy acoustic relative humidity measurement in duct flow with air.

    Science.gov (United States)

    van Schaik, Wilhelm; Grooten, Mart; Wernaart, Twan; van der Geld, Cees

    2010-01-01

    An acoustic relative humidity sensor for air-steam mixtures in duct flow is designed and tested. Theory, construction, calibration, considerations on dynamic response and results are presented. The measurement device is capable of measuring line averaged values of gas velocity, temperature and relative humidity (RH) instantaneously, by applying two ultrasonic transducers and an array of four temperature sensors. Measurement ranges are: gas velocity of 0-12 m/s with an error of ± 0.13 m/s, temperature 0-100 °C with an error of ± 0.07 °C and relative humidity 0-100% with accuracy better than 2 % RH above 50 °C. Main advantage over conventional humidity sensors is the high sensitivity at high RH at temperatures exceeding 50 °C, with accuracy increasing with increasing temperature. The sensors are non-intrusive and resist highly humid environments.

  2. Education-Related Parameters in High Myopia: Adults versus School Children.

    Directory of Open Access Journals (Sweden)

    Jost B Jonas

    Full Text Available Since high myopia in the younger generation may differ etiologically from high myopia in older generations, we examined whether education-related parameters differ between high myopia in today´s school children and high pathological myopia in today´s elderly generation.The investigation included the adult populations of the population-based Beijing Eye Study (BES (3468 adults;mean age:64.6±9.8years;range:50-93years and Central India Eye and Medical Study (CIEMS (4711 adults;age:49.±13.2years;range:30-100years, and the children and teenager populations of the Shandong Children Eye Study (SCES (6026 children;age:9.7±3.3years;range:4-18years;cycloplegic refractometry, Gobi Desert Children Eye Study (1565;age:11.9±3.5years;range:6-21 years;cycloplegic refractometry, Beijing Pediatric Eye Study (681 children;age:7.7±1.6years;range:5-13 years;non-cycloplegic refractometry,calculation of axial length to corneal curvature radius ratio, Beijing Children Eye Study (15066 children;age:13.2±3.4years;range:7-18years;non-cycloplegic refractometry, Beijing High School Teenager Eye Study (4677 children;age:16.9±0.7years;range:16-18years;non-cycloplegic refractometry.In the BES and CIEMS, educational level did not differ significantly between, or was significantly lower in the highly myopic group (myopic refractive error ≥6 diopters than in the non-highly myopic group. In all non-adult study populations, higher prevalence of high myopia was significantly associated with higher degree of education related parameters such as attendance of high-level schools, and more time spent for indoors near work versus time spent outdoors.Comparing associations of old or genetic high myopia in adults with new or acquired high myopia in school children revealed that education-related parameters did not show a clear association with old or genetic high myopia, while in contrast, new high myopia showed strong associations with education. It confirms previous studies

  3. Relation of high harmonic spectra to electronic structure in N2

    International Nuclear Information System (INIS)

    Farrell, J.P.; McFarland, B.K.; Guehr, M.; Bucksbaum, P.H.

    2009-01-01

    High harmonics of N 2 exhibit a number of features that are related to the electronic structure and sub-femtosecond dynamics of the molecule. Through measurements and simulations, we show how the harmonic spectral shape, spectral phase, alignment angle dependence, and intensity dependence can be related to the strong-field ionization and recombination dynamics of the HOMO and HOMO-1 electron orbitals. A field-free static model of the molecule is insufficient to explain the observations.

  4. Pembentukan Sikap Konsumen Pada Cause Related Marketing Produk Utilitarian Dan High Involvement

    OpenAIRE

    Singgih Santoso

    2016-01-01

    With popularity growing of social marketing concepts and consciousness of the environmental issues in recent days, cause related marketing activities oriented in environmental conservation issues is also growing. Research aims is to examine the formation of consumer attitudes on cause related marketing activities, a marketing activities which undertaken a commercial brand with a nonprofit organization; in this research product is utilitarian product and also high involvement product, namely A...

  5. Remote monitoring demonstration

    International Nuclear Information System (INIS)

    Caskey, Susan; Olsen, John

    2006-01-01

    The recently upgraded remote monitoring system at the Joyo Experimental Reactor uses a DCM-14 camera module and GEMINI software. The final data is compatible both with the IAEA-approved GARS review software and the ALIS software that was used for this demonstration. Features of the remote monitoring upgrade emphasized compatibility with IAEA practice. This presentation gives particular attention to the selection process for meeting network security considerations at the O'arai site. The Joyo system is different from the NNCA's ACPF system, in that it emphasizes use of IAEA standard camera technology and data acquisition and transmission software. In the demonstration itself, a temporary virtual private network (VPN) between the meeting room and the server at Sandia in Albuquerque allowed attendees to observe data stored from routine transmissions from the Joyo Fresh Fuel Storage to Sandia. Image files from a fuel movement earlier in the month showed Joyo workers and IAEA inspectors carrying out a transfer. (author)

  6. Commercial incineration demonstration

    International Nuclear Information System (INIS)

    Borduin, L.C.; Neuls, A.S.

    1981-01-01

    Low-level radioactive wastes (LLW) generated by nuclear utilities presently are shipped to commercial burial grounds for disposal. Substantially increasing shipping and disposal charges have sparked renewed industry interest in incineration and other advanced volume reduction techniques as potential cost-saving measures. Repeated inquiries from industry sources regarding LLW applicability of the Los Alamos controlled-air incineration (CAI) design led DOE to initiate this commercial demonstration program in FY-1980. The selected program approach to achieving CAI demonstration at a utility site is a DOE sponsored joint effort involving Los Alamos, a nuclear utility, and a liaison subcontractor. Required development tasks and responsibilities of the particpants are described. Target date for project completion is the end of FY-1985

  7. Photovoltaic demonstration projects

    Energy Technology Data Exchange (ETDEWEB)

    Kaut, W [Commission of the European Communities, Brussels (Belgium); Gillett, W B; Hacker, R J [Halcrow Gilbert Associates Ltd., Swindon (GB)

    1992-12-31

    This publication, comprising the proceedings of the fifth contractor`s meeting organized by the Commission of the European Communities, Directorate-General for Energy, provides an overview of the photovoltaic demonstration projects which have been supported in the framework of the energy demonstration programme since 1983. It includes reports by each of the contractors who submitted proposals in 1987 and 1988, describing progress within their projects. Projects accepted from earlier calls for proposals and not yet completed were reviewed by a rapporteur and are discussed in the summary section. The results of the performance monitoring of all projects and the lessons drawn from the practical experience of the projects are also presented in the summaries and conclusions. Contractors whose projects were submitted in 1989 were also present at the meeting and contributed to the reported discussions. This proceeding is divided into four sessions (General, Housing, technical presentations, other applications) and 24 papers are offered.

  8. AVNG system demonstration

    Energy Technology Data Exchange (ETDEWEB)

    Thron, Jonathan Louis [Los Alamos National Laboratory; Mac Arthur, Duncan W [Los Alamos National Laboratory; Kondratov, Sergey [VNIIEF; Livke, Alexander [VNIIEF; Razinkov, Sergey [VNIIEF

    2010-01-01

    An attribute measurement system (AMS) measures a number of unclassified attributes of potentially classified material. By only displaying these unclassified results as red or green lights, the AMS protects potentially classified information while still generating confidence in the measurement result. The AVNG implementation that we describe is an AMS built by RFNC - VNIIEF in Sarov, Russia. To provide additional confidence, the AVNG was designed with two modes of operation. In the secure mode, potentially classified measurements can be made with only the simple red light/green light display. In the open mode, known unclassified material can be measured with complete display of the information collected from the radiation detectors. The AVNG demonstration, which occurred in Sarov, Russia in June 2009 for a joint US/Russian audience, included exercising both modes of AVNG operation using a number of multi-kg plutonium sources. In addition to describing the demonstration, we will show photographs and/or video taken of AVNG operation.

  9. High-voltage measurements on the 5 ppm relative uncertainty level with collinear laser spectroscopy

    Science.gov (United States)

    Krämer, J.; König, K.; Geppert, Ch; Imgram, P.; Maaß, B.; Meisner, J.; Otten, E. W.; Passon, S.; Ratajczyk, T.; Ullmann, J.; Nörtershäuser, W.

    2018-04-01

    We present the results of high-voltage collinear laser spectroscopy measurements on the 5 ppm relative uncertainty level using a pump and probe scheme at the 4s ^2S1/2 → 4p ^2P3/2 transition of {\\hspace{0pt}}40Ca+ involving the 3d ^2D5/2 metastable state. With two-stage laser interaction and a reference measurement we can eliminate systematic effects such as differences in the contact potentials due to different electrode materials and thermoelectric voltages, and the unknown starting potential of the ions in the ion source. Voltage measurements were performed between  -5 kV and  -19 kV and parallel measurements with stable high-voltage dividers calibrated to 5 ppm relative uncertainty were used as a reference. Our measurements are compatible with the uncertainty limits of the high-voltage dividers and demonstrate an unprecedented (factor of 20) increase in the precision of direct laser-based high-voltage measurements.

  10. Antares: preliminary demonstrator results

    International Nuclear Information System (INIS)

    Kouchner, A.

    2000-05-01

    The ANTARES collaboration is building an undersea neutrino telescope off Toulon (Mediterranean sea) with effective area ∼ 0.1 km 2 . An extensive study of the site properties has been achieved together with software analysis in order to optimize the performance of the detector. Results are summarized here. An instrumented line, linked to shore for first time via an electro-optical cable, has been immersed late 1999. The preliminary results of this demonstrator line are reported. (author)

  11. The Majorana Demonstrator

    Energy Technology Data Exchange (ETDEWEB)

    Aguayo, Estanislao; Fast, James E.; Hoppe, Eric W.; Keillor, Martin E.; Kephart, Jeremy D.; Kouzes, Richard T.; LaFerriere, Brian D.; Merriman, Jason H.; Orrell, John L.; Overman, Nicole R.; Avignone, Frank T.; Back, Henning O.; Combs, Dustin C.; Leviner, L.; Young, A.; Barabash, Alexander S.; Konovalov, S.; Vanyushin, I.; Yumatov, Vladimir; Bergevin, M.; Chan, Yuen-Dat; Detwiler, Jason A.; Loach, J. C.; Martin, R. D.; Poon, Alan; Prior, Gersende; Vetter, Kai; Bertrand, F.; Cooper, R. J.; Radford, D. C.; Varner, R. L.; Yu, Chang-Hong; Boswell, M.; Elliott, S.; Gehman, Victor M.; Hime, Andrew; Kidd, M. F.; LaRoque, B. H.; Rielage, Keith; Ronquest, M. C.; Steele, David; Brudanin, V.; Egorov, Viatcheslav; Gusey, K.; Kochetov, Oleg; Shirchenko, M.; Timkin, V.; Yakushev, E.; Busch, Matthew; Esterline, James H.; Tornow, Werner; Christofferson, Cabot-Ann; Horton, Mark; Howard, S.; Sobolev, V.; Collar, J. I.; Fields, N.; Creswick, R.; Doe, Peter J.; Johnson, R. A.; Knecht, A.; Leon, Jonathan D.; Marino, Michael G.; Miller, M. L.; Robertson, R. G. H.; Schubert, Alexis G.; Wolfe, B. A.; Efremenko, Yuri; Ejiri, H.; Hazama, R.; Nomachi, Masaharu; Shima, T.; Finnerty, P.; Fraenkle, Florian; Giovanetti, G. K.; Green, M.; Henning, Reyco; Howe, M. A.; MacMullin, S.; Phillips, D.; Snavely, Kyle J.; Strain, J.; Vorren, Kris R.; Guiseppe, Vincente; Keller, C.; Mei, Dong-Ming; Perumpilly, Gopakumar; Thomas, K.; Zhang, C.; Hallin, A. L.; Keeter, K.; Mizouni, Leila; Wilkerson, J. F.

    2011-09-03

    A brief review of the history and neutrino physics of double beta decay is given. A description of the MAJORANA DEMONSTRATOR research and development program, including background reduction techniques, is presented in some detail. The application of point contact (PC) detectors to the experiment is discussed, including the effectiveness of pulse shape analysis. The predicted sensitivity of a PC detector array enriched to 86% to 76Ge is given.

  12. IGCC technology and demonstration

    Energy Technology Data Exchange (ETDEWEB)

    Palonen, J [A. Ahlstrom Corporation, Karhula (Finland). Hans Ahlstrom Lab.; Lundqvist, R G [A. Ahlstrom Corporation, Helsinki (Finland); Staahl, K [Sydkraft AB, Malmoe (Sweden)

    1997-12-31

    Future energy production will be performed by advanced technologies that are more efficient, more environmentally friendly and less expensive than current technologies. Integrated gasification combined cycle (IGCC) power plants have been proposed as one of these systems. Utilising biofuels in future energy production will also be emphasised since this lowers substantially carbon dioxide emissions into the atmosphere due to the fact that biomass is a renewable form of energy. Combining advanced technology and biomass utilisation is for this reason something that should and will be encouraged. A. Ahlstrom Corporation of Finland and Sydkraft AB of Sweden have as one part of company strategies adopted this approach for the future. The companies have joined their resources in developing a biomass-based IGCC system with the gasification part based on pressurised circulating fluidized-bed technology. With this kind of technology electrical efficiency can be substantially increased compared to conventional power plants. As a first concrete step, a decision has been made to build a demonstration plant. This plant, located in Vaernamo, Sweden, has already been built and is now in commissioning and demonstration stage. The system comprises a fuel drying plant, a pressurised CFB gasifier with gas cooling and cleaning, a gas turbine, a waste heat recovery unit and a steam turbine. The plant is the first in the world where the integration of a pressurised gasifier with a gas turbine will be realised utilising a low calorific gas produced from biomass. The capacity of the Vaernamo plant is 6 MW of electricity and 9 MW of district heating. Technology development is in progress for design of plants of sizes from 20 to 120 MWe. The paper describes the Bioflow IGCC system, the Vaernamo demonstration plant and experiences from the commissioning and demonstration stages. (orig.)

  13. IGCC technology and demonstration

    Energy Technology Data Exchange (ETDEWEB)

    Palonen, J. [A. Ahlstrom Corporation, Karhula (Finland). Hans Ahlstrom Lab.; Lundqvist, R.G. [A. Ahlstrom Corporation, Helsinki (Finland); Staahl, K. [Sydkraft AB, Malmoe (Sweden)

    1996-12-31

    Future energy production will be performed by advanced technologies that are more efficient, more environmentally friendly and less expensive than current technologies. Integrated gasification combined cycle (IGCC) power plants have been proposed as one of these systems. Utilising biofuels in future energy production will also be emphasised since this lowers substantially carbon dioxide emissions into the atmosphere due to the fact that biomass is a renewable form of energy. Combining advanced technology and biomass utilisation is for this reason something that should and will be encouraged. A. Ahlstrom Corporation of Finland and Sydkraft AB of Sweden have as one part of company strategies adopted this approach for the future. The companies have joined their resources in developing a biomass-based IGCC system with the gasification part based on pressurised circulating fluidized-bed technology. With this kind of technology electrical efficiency can be substantially increased compared to conventional power plants. As a first concrete step, a decision has been made to build a demonstration plant. This plant, located in Vaernamo, Sweden, has already been built and is now in commissioning and demonstration stage. The system comprises a fuel drying plant, a pressurised CFB gasifier with gas cooling and cleaning, a gas turbine, a waste heat recovery unit and a steam turbine. The plant is the first in the world where the integration of a pressurised gasifier with a gas turbine will be realised utilising a low calorific gas produced from biomass. The capacity of the Vaernamo plant is 6 MW of electricity and 9 MW of district heating. Technology development is in progress for design of plants of sizes from 20 to 120 MWe. The paper describes the Bioflow IGCC system, the Vaernamo demonstration plant and experiences from the commissioning and demonstration stages. (orig.)

  14. Lunar Water Resource Demonstration

    Science.gov (United States)

    Muscatello, Anthony C.

    2008-01-01

    In cooperation with the Canadian Space Agency, the Northern Centre for Advanced Technology, Inc., the Carnegie-Mellon University, JPL, and NEPTEC, NASA has undertaken the In-Situ Resource Utilization (ISRU) project called RESOLVE. This project is a ground demonstration of a system that would be sent to explore permanently shadowed polar lunar craters, drill into the regolith, determine what volatiles are present, and quantify them in addition to recovering oxygen by hydrogen reduction. The Lunar Prospector has determined these craters contain enhanced hydrogen concentrations averaging about 0.1%. If the hydrogen is in the form of water, the water concentration would be around 1%, which would translate into billions of tons of water on the Moon, a tremendous resource. The Lunar Water Resource Demonstration (LWRD) is a part of RESOLVE designed to capture lunar water and hydrogen and quantify them as a backup to gas chromatography analysis. This presentation will briefly review the design of LWRD and some of the results of testing the subsystem. RESOLVE is to be integrated with the Scarab rover from CMIJ and the whole system demonstrated on Mauna Kea on Hawaii in November 2008. The implications of lunar water for Mars exploration are two-fold: 1) RESOLVE and LWRD could be used in a similar fashion on Mars to locate and quantify water resources, and 2) electrolysis of lunar water could provide large amounts of liquid oxygen in LEO, leading to lower costs for travel to Mars, in addition to being very useful at lunar outposts.

  15. Epidemiology, trends, assessment and management of sport-related concussion in United States high schools.

    Science.gov (United States)

    Guerriero, Réjean M; Proctor, Mark R; Mannix, Rebekah; Meehan, William P

    2012-12-01

    Sport-related concussion affects athletes at every level of participation. The short and long-term effects of concussions that occur during childhood and adolescence are not fully understood. The purpose of this review is to describe the current burden of disease, current practice patterns and current recommendations for the assessment and management of sport-related concussions sustained by United States high school athletes. Millions of high school students participate in organized sports in the United States. Current estimates suggest that, across all sports, approximately 2.5 concussions occur for every 10 000 athletic exposures, in which an athletic exposure is defined as one athlete participating in one game or practice. At schools that employ at least one athletic trainer, most high school athletes who sustain sport-related concussions will be cared for by athletic trainers and primary care physicians. Approximately 40% will undergo computerized neurocognitive assessment. The number of high school athletes being diagnosed with sport-related concussions is rising. American football has the highest number of concussions in high school with girls' soccer having the second highest total number. Fortunately, coaches are becoming increasingly aware of these injuries and return-to-play guidelines are being implemented.

  16. Analysis of relation between geomorphologic processes and alpine vegetation in the high mountain landscape (Tatry Mts.)

    International Nuclear Information System (INIS)

    Boltiziar, M.

    2003-01-01

    The aim was to present some information about starting of high mountains ecological monitoring and its first partial results. The research is focused on a long-term observation of vegetation changes (species composition, species spatial distribution) in relation to geomorphic processes and geo-relief attributes at meso- and micro-scale of landscape. We established in 2002 for this purpose six permanent plots (4 x 4 m) in the selected localities of High and Belianske Tatras Mts. (Author)

  17. Prevalence of Depression among High School Students and its Relation to Family Structure

    OpenAIRE

    Ali Daryanavard; Abdoulhossain Madani; Mohammad S. Mahmoodi; Shafei Rahimi; Fatemeh Nourooziyan; Mahmood Hosseinpoor

    2011-01-01

    Problem statement: Depression is common in adolescents and especially in high school students. The aim of this study was to determine the prevalence of depression among high school students and its relation to parental configurations. Approach: A cross-sectional study was conducted during first term of the academic year 2003-2004. Data was collected by Beck Depression Inventory questionnaire (BDI-21 test) and researcher made questionnaire for demographic characteristics, using census procedur...

  18. Metallorganic precursors route for high Tc superconducting materials and related phases

    International Nuclear Information System (INIS)

    Beltran-porter, D.; Gonzalez, A.; Sanchis, M.J.; Beltran-porter, A.; Ibanez, R.; Sapina, F.

    1991-01-01

    The adequacy of the precursors approach for high Tc superconducting materials is validated by means of three examples of a new synthesis of mixed oxides which are directly related to the high Tc superconductors. The synthesis temperature is lowered significantly, and the need for extending the classic 'building block' approach is shown. The hypothesis that topochemical reactions from molecular to extended solids are posssible is proven. 28 refs

  19. Work-related fatigue: the specific case of highly educated women in the Netherlands

    OpenAIRE

    Verdonk, Petra; Hooftman, Wendela E.; van Veldhoven, Marc J. P. M.; Boelens, Louise R. M.; Koppes, Lando L. J.

    2009-01-01

    Purpose This study aims to establish the prevalence of high work-related fatigue (need for recovery, NFR) among employees and to explain group differences categorized by gender, age, and education. The study particularly aims to clarify prevalence and explanatory factors in highly educated women. Methods In 2005 and 2006, large representative samples of 80,000 Dutch employees (net response rate 33.0%; N?=?47,263) received the Netherlands working conditions survey questionnaire. First, we calc...

  20. Application of high-throughput sequencing in understanding human oral microbiome related with health and disease

    OpenAIRE

    Chen, Hui; Jiang, Wen

    2014-01-01

    The oral microbiome is one of most diversity habitat in the human body and they are closely related with oral health and disease. As the technique developing,, high throughput sequencing has become a popular approach applied for oral microbial analysis. Oral bacterial profiles have been studied to explore the relationship between microbial diversity and oral diseases such as caries and periodontal disease. This review describes the application of high-throughput sequencing for characterizati...

  1. International note: between-domain relations of Chinese high school students' academic achievements.

    Science.gov (United States)

    Yangyang, Liu

    2012-08-01

    The present study examined the between-domain relations of Chinese high school students' academic achievements. In a sample of 1870 Chinese 10th grade students, the results indicated that Chinese high school students' academic achievements were correlated across nine subjects. In line with the previous Western findings, the findings suggested that academic achievement was largely domain-general in nature. Copyright © 2012 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

  2. Work-related fatigue: the specific case of highly educated women in the Netherlands.

    Science.gov (United States)

    Verdonk, Petra; Hooftman, Wendela E; van Veldhoven, Marc J P M; Boelens, Louise R M; Koppes, Lando L J

    2010-03-01

    This study aims to establish the prevalence of high work-related fatigue (need for recovery, NFR) among employees and to explain group differences categorized by gender, age, and education. The study particularly aims to clarify prevalence and explanatory factors in highly educated women. In 2005 and 2006, large representative samples of 80,000 Dutch employees (net response rate 33.0%; N = 47,263) received the Netherlands working conditions survey questionnaire. First, we calculated the prevalence of high NFR for men and women with different age and education levels. The average prevalence of high NFR was 28.8% and was highest among highly educated women (35.2%) in particular those aged 50-64 years (40.3%). Second, logistic regression analyses were used to compare subgroups' NFR in relation to situational factors, working conditions, and health. Three comparisons were made: (1) highly educated women versus men; (2) highly educated versus lower educated women and; (3) older highly educated versus younger highly educated women. The situational, working conditions and health factors in our model did not explain the gender differences among highly educated employees (OR = 1.37; CI = 1.3-1.5, adjusted for all factors OR = 1.32; CI = 1.2-1.5). Despite that lower autonomy and workplace violence explained highly educated women's NFR, working fewer hours counterbalanced this. Time pressure in work largely explained the differences in NFR among women at different education levels (crude OR 1.44; CI = 1.4-1.5, adjusted OR 1.14; CI = 1.0-1.3). In the age comparison, lower health ratings, more adverse working conditions, and working as a teacher explained older highly educated women's high prevalence of high NFR (crude OR 1.32; CI = 1.2-1.5, adjusted OR 0.94; CI = 0.8-1.2). NFR has high prevalence in highly educated women (35.2%) in particular those aged 50-64 years (40.3%). Our model did not explain gender differences in NFR, because working fewer hours counterbalanced the

  3. IgG4-related hypophysitis is highly prevalent among cases of histologically confirmed hypophysitis.

    Science.gov (United States)

    Bernreuther, Christian; Illies, Christopher; Flitsch, Jörg; Buchfelder, Michael; Buslei, Rolf; Glatzel, Markus; Saeger, Wolfgang

    2017-11-01

    IgG4-related disease is an immune-mediated disease with manifestations in most organ systems among them the pituitary gland. To date, few cases of histologically confirmed cases of IgG-related hypophysitis have been reported. The aim of this study was to retrospectively determine the prevalence of IgG4-related hypophysitis among cases previously diagnosed as primary hypophysitis (lymphocytic hypophysitis, granulomatous hypophysitis and hypophysitis not otherwise specified). Histological and immunohistochemical analysis revealed that 12 of 29 cases (41.4%) previously diagnosed as primary hypophysitis fulfilled the criteria for IgG4-related disease and, thus, IgG4-related hypophysitis should always be considered in the differential diagnosis of primary hypophysitis. All cases of IgG4-related hypophysitis showed a dense lymphoplasmacytic infiltrate with more than 10 IgG4-positive cells per high power field and a ratio of IgG4/IgG-positive cells of more than 40%, whereas storiform fibrosis was an inconsistent histological feature and was also seen in few cases of non-IgG-related hypophysitis, thus lacking sensitivity and specificity. Obliterative phlebitis was not seen in any case. Thus, histological criteria defined for IgG4-related disease in other organs should be modified for IgG4-related hypophysitis, accordingly. © 2016 International Society of Neuropathology.

  4. Environmental analysis for pipeline gas demonstration plants

    Energy Technology Data Exchange (ETDEWEB)

    Stinton, L.H.

    1978-09-01

    The Department of Energy (DOE) has implemented programs for encouraging the development and commercialization of coal-related technologies, which include coal gasification demonstration-scale activities. In support of commercialization activities the Environmental Analysis for Pipeline Gas Demonstration Plants has been prepared as a reference document to be used in evaluating potential environmental and socioeconomic effects from construction and operation of site- and process-specific projects. Effluents and associated impacts are identified for six coal gasification processes at three contrasting settings. In general, impacts from construction of a high-Btu gas demonstration plant are similar to those caused by the construction of any chemical plant of similar size. The operation of a high-Btu gas demonstration plant, however, has several unique aspects that differentiate it from other chemical plants. Offsite development (surface mining) and disposal of large quantities of waste solids constitute important sources of potential impact. In addition, air emissions require monitoring for trace metals, polycyclic aromatic hydrocarbons, phenols, and other emissions. Potential biological impacts from long-term exposure to these emissions are unknown, and additional research and data analysis may be necessary to determine such effects. Possible effects of pollutants on vegetation and human populations are discussed. The occurrence of chemical contaminants in liquid effluents and the bioaccumulation of these contaminants in aquatic organisms may lead to adverse ecological impact. Socioeconomic impacts are similar to those from a chemical plant of equivalent size and are summarized and contrasted for the three surrogate sites.

  5. Visual Electricity Demonstrator

    Science.gov (United States)

    Lincoln, James

    2017-09-01

    The Visual Electricity Demonstrator (VED) is a linear diode array that serves as a dynamic alternative to an ammeter. A string of 48 red light-emitting diodes (LEDs) blink one after another to create the illusion of a moving current. Having the current represented visually builds an intuitive and qualitative understanding about what is happening in a circuit. In this article, I describe several activities for this device and explain how using this technology in the classroom can enhance the understanding and appreciation of physics.

  6. Exploration Medical System Demonstration

    Science.gov (United States)

    Rubin, D. A.; Watkins, S. D.

    2014-01-01

    BACKGROUND: Exploration class missions will present significant new challenges and hazards to the health of the astronauts. Regardless of the intended destination, beyond low Earth orbit a greater degree of crew autonomy will be required to diagnose medical conditions, develop treatment plans, and implement procedures due to limited communications with ground-based personnel. SCOPE: The Exploration Medical System Demonstration (EMSD) project will act as a test bed on the International Space Station (ISS) to demonstrate to crew and ground personnel that an end-to-end medical system can assist clinician and non-clinician crew members in optimizing medical care delivery and data management during an exploration mission. Challenges facing exploration mission medical care include limited resources, inability to evacuate to Earth during many mission phases, and potential rendering of medical care by non-clinicians. This system demonstrates the integration of medical devices and informatics tools for managing evidence and decision making and can be designed to assist crewmembers in nominal, non-emergent situations and in emergent situations when they may be suffering from performance decrements due to environmental, physiological or other factors. PROJECT OBJECTIVES: The objectives of the EMSD project are to: a. Reduce or eliminate the time required of an on-orbit crew and ground personnel to access, transfer, and manipulate medical data. b. Demonstrate that the on-orbit crew has the ability to access medical data/information via an intuitive and crew-friendly solution to aid in the treatment of a medical condition. c. Develop a common data management framework that can be ubiquitously used to automate repetitive data collection, management, and communications tasks for all activities pertaining to crew health and life sciences. d. Ensure crew access to medical data during periods of restricted ground communication. e. Develop a common data management framework that

  7. Commercial incineration demonstration

    International Nuclear Information System (INIS)

    Vavruska, J.S.; Borduin, L.C.

    1982-01-01

    Low-level radioactive wastes (LLW) generated by nuclear utilities presently are shipped to commercial burial grounds for disposal. Increasing transportation and disposal costs have caused industry to consider incineration as a cost-effective means of volume reduction of combustible LLW. Repeated inquiries from the nuclear industry regarding the applicability of the Los Alamos controlled air incineration (CAI) design led the DOE to initiate a commercial demonstration program in FY-1980. Development studies and results in support of this program involving ion exchange resin incineration and fission/activation product distributions within the Los Alamos CAI are described

  8. Demonstration tokamak power plant

    International Nuclear Information System (INIS)

    Abdou, M.; Baker, C.; Brooks, J.; Ehst, D.; Mattas, R.; Smith, D.L.; DeFreece, D.; Morgan, G.D.; Trachsel, C.

    1983-01-01

    A conceptual design for a tokamak demonstration power plant (DEMO) was developed. A large part of the study focused on examining the key issues and identifying the R and D needs for: (1) current drive for steady-state operation, (2) impurity control and exhaust, (3) tritium breeding blanket, and (4) reactor configuration and maintenance. Impurity control and exhaust will not be covered in this paper but is discussed in another paper in these proceedings, entitled Key Issues of FED/INTOR Impurity Control System

  9. Health-related quality of life of long-term high-grade glioma survivors

    NARCIS (Netherlands)

    Bosma, Ingeborg; Reijneveld, Jaap C.; Douw, Linda; Vos, Maaike J.; Postma, Tjeerd J.; Aaronson, Neil K.; Muller, Martin; Vandertop, W. Peter; Slotman, Ben J.; Taphoorn, Martin J. B.; Heimans, Jan J.; Klein, Martin

    2009-01-01

    The objective of this study was to compare the health-related quality of life (HRQOL) of long-term to short-term high-grade glioma (HGG) survivors, determine the prognostic value of HRQOL for overall survival, and determine the effect of tumor recurrence on HRQOL for long-term survivors. Following

  10. Haptoglobin-related protein is a high-affinity hemoglobin-binding plasma protein

    DEFF Research Database (Denmark)

    Nielsen, Marianne Jensby; Petersen, Steen Vang; Jacobsen, Christian

    2006-01-01

    Haptoglobin-related protein (Hpr) is a primate-specific plasma protein associated with apolipoprotein L-I (apoL-I)-containing high-density lipoprotein (HDL) particles shown to be a part of the innate immune defense. Despite the assumption hitherto that Hpr does not bind to hemoglobin, the present...

  11. [Work-related fatigue in highly-educated women older than 50].

    NARCIS (Netherlands)

    Knoers, N.V.A.M.

    2010-01-01

    Recent findings by Verdonk et al. show that the prevalence of work-related fatigue among 47,000 Dutch employees is greatest in highly-educated women, aged 50-64 years. Although the study has several limitations, the findings are alarming, demand urgent measures and should be on the shortlist of

  12. School District Wellness Policy Quality and Weight-Related Outcomes among High School Students in Minnesota

    Science.gov (United States)

    Hoffman, Pamela K.; Davey, Cynthia S.; Larson, Nicole; Grannon, Katherine Y.; Hanson, Carlie; Nanney, Marilyn S.

    2016-01-01

    Weight-related outcomes were examined among high school students in Minnesota public school districts according to the quality of district wellness policies. Wellness policy strength and comprehensiveness were scored using the Wellness School Assessment Tool (WellSAT) for 325 Minnesota public school districts in 2013. The associations between…

  13. Gender differences in trajectories of relational aggression perpetration and victimization from middle to high school.

    Science.gov (United States)

    Orpinas, Pamela; McNicholas, Caroline; Nahapetyan, Lusine

    2015-01-01

    Relational aggression refers to harming others through damaging or manipulating peer relationships. In a cohort of students surveyed annually from middle to high school, this study identified groups of adolescents who followed distinct trajectories of perpetration and of victimization of relational aggression, compared the proportion of boys and girls in each trajectory, and examined the overlap between perpetration and victimization trajectories. The sample consisted of 620 randomly selected sixth graders. Students completed yearly surveys from Grade 6-12. We used group-based trajectory modeling to identify the trajectories. Adolescents followed three developmental trajectories of perpetration and three similar trajectories of victimization: Low (lowest aggression), Moderate, and High Declining (high in middle school, with a steep decline in high school). All trajectories declined from Grade 6-12. The largest groups were the Low perpetration (55%) and Low victimization (48%). Relational aggression trajectories differed by gender: more boys reported perpetration, and more girls reported victimization. For perpetration, slightly more boys than girls were classified in the two trajectories of higher aggression. For victimization, significantly fewer girls than boys were classified in the Low trajectory, and significantly more girls than boys were classified in the Moderate trajectory. There was substantial overlap of the perpetration and victimization trajectories. These findings highlight the importance of implementing programs to reduce relational aggression for boys and for girls. © 2014 Wiley Periodicals, Inc.

  14. Gender Differences in Factors Related to Parenting Styles: A Study of High Performing Science Students.

    Science.gov (United States)

    Hein, Carol; Lewko, John H.

    1994-01-01

    Examined parenting styles within families of high performing science students and explored gender differences in the factors associated with authoritative parenting style. Found that the authoritative parenting style was predominant among study participants and that a greater number of family-related variables emerge for females, whereas more…

  15. "Approaches to the Teaching of Special Relativity Theory in High School and University Textbooks of Argentina"

    Science.gov (United States)

    Arriassecq, Irene; Greca, Ileana Maria

    2007-01-01

    In this work, we presented an analysis of the representation of the special relativity theory (SRT) in the most used texts in high school, Polimodal level and university level in the teaching in the Argentine Republic, from a historic, epistemological and didactic perspective. The results show that none of the analyzed texts would allow a…

  16. The burden of high blood pressure and related risk factors in urban ...

    African Journals Online (AJOL)

    Objective: To provide the current burden of high blood pressure and related risk factors in urban setting in Cameroon. Methods:We used the WHO STEPS approach for Surveillance of non-communicable diseases and their risk factors to collect data from 2,559 adults aged 15-99 years, residing at Cite des Palmiers in Douala ...

  17. The Study of Relations between Life Satisfaction, Burnout, Work Engagement and Hopelessness of High School Students

    Science.gov (United States)

    Çapri, Burhan; Gündüz, Bülent; Akbay, Sinem Evin

    2013-01-01

    The purpose of this research is to determine the relations between high school students' life satisfaction, burnout, work engagement and hopelessness scores and examine the contribution of their burnout, work engagement and hopelessness scores in the prediction of their life satisfaction scores. The Satisfaction with Life Scale (SWLS), Maslach…

  18. Humor in High School and the Role of Teacher Leaders in School Public Relations

    Science.gov (United States)

    Kosiczky, Bonnie; Mullen, Carol A.

    2013-01-01

    How can public schools improve public relations strategies, particularly in communications between teachers and students? The purposes of this study were to investigate teacher leaders' perceptions of the use of humor in the high school classroom and discover how humor might bridge instruction to student learning and strengthen teacher-student…

  19. The Relative Importance of Low Significance Level and High Power in Multiple Tests of Significance.

    Science.gov (United States)

    Westermann, Rainer; Hager, Willi

    1983-01-01

    Two psychological experiments--Anderson and Shanteau (1970), Berkowitz and LePage (1967)--are reanalyzed to present the problem of the relative importance of low Type 1 error probability and high power when answering a research question by testing several statistical hypotheses. (Author/PN)

  20. High/Scope Preschool Key Experiences: Initiative and Social Relations. [with] Curriculum Videotape.

    Science.gov (United States)

    Graves, Michelle

    As preschoolers develop the ability to carry out their ideas and play alone and with others, they are developing the foundation for social competence. This booklet and a companion videotape help teachers and parents recognize and support nine High/Scope key experiences in initiative and social relations: (1) making and expressing choices, plans,…

  1. Women Leaders in High-Poverty Community Schools: Work-Related Stress and Family Impact

    Science.gov (United States)

    Lawson, Jennifer E.

    2008-01-01

    This qualitative study explores the experiences of women administrators in high-poverty community schools, investigating four women's perspectives on work demands and the impact on their families. Their work demands are related to the characteristics of impoverished communities, whereas their work resources are based on intrinsic rewards and…

  2. Maladaptive Personality and Neuropsychological Features of Highly Relationally Aggressive Adolescent Girls

    Directory of Open Access Journals (Sweden)

    Michael Savage

    2017-07-01

    Full Text Available The maladaptive personality and neuropsychological features of highly relationally aggressive females were examined in a group of 30 grade 6, 7, and 8 girls and group-matched controls. Employing a multistage cluster sampling procedure a group of highly, yet almost exclusively, relationally aggressive females were identified and matched on a number of variables to a group of nonaggressive females. Parents of the students in both groups completed the Coolidge Personality and Neuropsychological Inventory, a 200-item DSM-IV-TR aligned, parent-as-respondent, standardized measure of children’s psychological functioning. It was found that high levels of relational aggression, in the absence of physical and verbal aggression, were associated with symptoms of DSM-IV-TR Axis I oppositional defiant disorder and conduct disorder. The highly relationally aggressive group also exhibited a wide variety of personality traits associated with DSM-IV-TR Axis II paranoid, borderline, narcissistic, histrionic, schizotypal, and passive aggressive personality disorders that were not exhibited by the matched controls. Implications of these findings are discussed.

  3. Dispersion relation and Landau damping of waves in high-energy density plasmas

    International Nuclear Information System (INIS)

    Zhu Jun; Ji Peiyong

    2012-01-01

    We present a theoretical investigation on the propagation of electromagnetic waves and electron plasma waves in high energy density plasmas using the covariant Wigner function approach. Based on the covariant Wigner function and Dirac equation, a relativistic quantum kinetic model is established to describe the physical processes in high-energy density plasmas. With the zero-temperature Fermi–Dirac distribution, the dispersion relation and Landau damping of waves containing the relativistic quantum corrected terms are derived. The relativistic quantum corrections to the dispersion relation and Landau damping are analyzed by comparing our results with those obtained in classical and non-relativistic quantum plasmas. We provide a detailed discussion on the Landau damping obtained in classical plasmas, non-relativistic Fermi plasmas and relativistic Fermi plasmas. The contributions of the Bohm potential, the Fermi statistics pressure and relativistic effects to the dispersion relation and Landau damping of waves are quantitatively calculated with real plasma parameters. (paper)

  4. Smoking Frequency and some Related Factors among High School Students of Kashan City, Iran

    Directory of Open Access Journals (Sweden)

    Hammamizade O.R.1 BSc,

    2015-09-01

    Full Text Available Aims The dramatic increase of smoking in adolescents has become one of the major challenges in most countries and it needs further consideration. The aim of this study was to determine the smoking prevalence and some related factors among high school students. Instrument & Methods This descriptive, cross-sectional study was done in 2012-13 academic year in male and female high school students of Kashan City, Iran and 328 students were selected by multi-stage random cluster sampling method. Data were collected by a researcher-made questionnaire which had three parts; demographic data, history of smoking in the family, and ways of smoking. Data analysis was done using Chi-square and ANOVA tests. Findings 19.3% (52 students of the high school students of Kashan City, Iran, were smokers; 41 boys (20.2% and 11 girls (8.8%. Smoking had significant relations with sex, grade and having a smoker in the family. 30.3% of the students had a cigarette smoker and 32.40% had a hookah smoker in their family. Hookah was the most prevalent tobacco product. Friends (47.8% in boys and 10.4% in girls and then relatives (13.4% in boys and 8.2% in girls contributed to students’ smoking. Conclusion Smoking hookah and cigarette have a high prevalence in sophomore and junior high school boys and having a smoker family member or friend is a main risk factor of start smoking in adolescents.

  5. Physical and relational aggression as predictors of drug use: gender differences among high school students.

    Science.gov (United States)

    Skara, Silvana; Pokhrel, Pallav; Weiner, Michelle D; Sun, Ping; Dent, Clyde W; Sussman, Steve

    2008-12-01

    The present study investigated the longitudinal relationships between physical and relational aggression and later drug use, as moderated by gender. Self-reported data were gathered from 2064 high school students at pretest and 1-year post-test to test the hypotheses that (1) males would engage in more physical aggression than females, whereas females would engage in more relational aggression than males; and (2) physical aggression would be a stronger drug use predictor for males and relational aggression a stronger predictor for females. Results indicated that males reported engaging in more physical aggression than females at baseline; however, females and males reported engaging in similar rates of relational aggression. After controlling for relational aggression, baseline drug use, and demographic variables, physical aggression at baseline was found to predict alcohol use 1-year later for males but not for females. After controlling for physical aggression, baseline drug use, and demographic variables, relational aggression was found to predict cigarette use and marijuana use for females but not for males. However, relational aggression was found to predict later alcohol and hard drug equally across gender. These findings suggest that both physical and relational aggression are predictive of subsequent drug use and have important implications for violence and drug use prevention intervention efforts.

  6. Relations between high and low power groups: the importance of legitimacy.

    Science.gov (United States)

    Hornsey, Matthew J; Spears, Russell; Cremers, Iris; Hogg, Michael A

    2003-02-01

    Using a social identity perspective, two experiments examined the effects of power and the legitimacy of power differentials on intergroup bias. In Experiment 1, 125 math-science students were led to believe that they had high or low representation in a university decision-making body relative to social-science students and that this power position was either legitimate or illegitimate. Power did not have an independent effect on bias; rather, members of both high and low power groups showed more bias when the power hierarchy was illegitimate than when it was legitimate. This effect was replicated in Experiment 2 (N = 105). In addition, Experiment 2 showed that groups located within an unfair power hierarchy expected the superordinate power body to be more discriminatory than did those who had legitimately high or low power. The results are discussed in terms of their implications for group relations. Copyright 2003 Society for Personality and Social Psychology, Inc.

  7. Electrodynamic Dust Shield Demonstrator

    Science.gov (United States)

    Stankie, Charles G.

    2013-01-01

    The objective of the project was to design and manufacture a device to demonstrate a new technology developed by NASA's Electrostatics and Surface Physics Laboratory. The technology itself is a system which uses magnetic principles to remove regolith dust from its surface. This project was to create an enclosure that will be used to demonstrate the effectiveness of the invention to The Office of the Chief Technologist. ONE of the most important challenges of space exploration is actually caused by something very small and seemingly insignificant. Dust in space, most notably on the moon and Mars, has caused many unforeseen issues. Dirt and dust on Earth, while a nuisance, can be easily cleaned and kept at bay. However, there is considerably less weathering and erosion in space. As a result, the microscopic particles are extremely rough and abrasive. They are also electrostatically charged, so they cling to everything they make contact with. This was first noted to be a major problem during the Apollo missions. Dust would stick to the spacesuits, and could not be wiped off as predicted. Dust was brought back into the spacecraft, and was even inhaled by astronauts. This is a major health hazard. Atmospheric storms and other events can also cause dust to coat surfaces of spacecraft. This can cause abrasive damage to the craft. The coating can also reduce the effectiveness of thermal insulation and solar panels.' A group of engineers at Kennedy Space Center's Electrostatics and Surface Physics Laboratory have developed a new technology, called the Electrodynamic Dust Shield, to help alleviate these problems. It is based off of the electric curtain concept developed at NASA in 1967. "The EDS is an active dust mitigation technology that uses traveling electric fields to transport electrostatically charged dust particles along surfaces. To generate the traveling electric fields, the EDS consists of a multilayer dielectric coating with an embedded thin electrode grid

  8. Fuel Cell Demonstration Program

    Energy Technology Data Exchange (ETDEWEB)

    Gerald Brun

    2006-09-15

    In an effort to promote clean energy projects and aid in the commercialization of new fuel cell technologies the Long Island Power Authority (LIPA) initiated a Fuel Cell Demonstration Program in 1999 with six month deployments of Proton Exchange Membrane (PEM) non-commercial Beta model systems at partnering sites throughout Long Island. These projects facilitated significant developments in the technology, providing operating experience that allowed the manufacturer to produce fuel cells that were half the size of the Beta units and suitable for outdoor installations. In 2001, LIPA embarked on a large-scale effort to identify and develop measures that could improve the reliability and performance of future fuel cell technologies for electric utility applications and the concept to establish a fuel cell farm (Farm) of 75 units was developed. By the end of October of 2001, 75 Lorax 2.0 fuel cells had been installed at the West Babylon substation on Long Island, making it the first fuel cell demonstration of its kind and size anywhere in the world at the time. Designed to help LIPA study the feasibility of using fuel cells to operate in parallel with LIPA's electric grid system, the Farm operated 120 fuel cells over its lifetime of over 3 years including 3 generations of Plug Power fuel cells (Lorax 2.0, Lorax 3.0, Lorax 4.5). Of these 120 fuel cells, 20 Lorax 3.0 units operated under this Award from June 2002 to September 2004. In parallel with the operation of the Farm, LIPA recruited government and commercial/industrial customers to demonstrate fuel cells as on-site distributed generation. From December 2002 to February 2005, 17 fuel cells were tested and monitored at various customer sites throughout Long Island. The 37 fuel cells operated under this Award produced a total of 712,635 kWh. As fuel cell technology became more mature, performance improvements included a 1% increase in system efficiency. Including equipment, design, fuel, maintenance

  9. Suppressing images of desire: Neural correlates of chocolate-related thoughts in high and low trait chocolate cravers.

    Science.gov (United States)

    Miedl, Stephan F; Blechert, Jens; Meule, Adrian; Richard, Anna; Wilhelm, Frank H

    2018-03-05

    Chocolate is the most often craved food in Western societies and many individuals try to resist its temptation due to weight concerns. Suppressing chocolate-related thoughts might, however, lead to paradoxical enhancements of these thoughts and this effect might be more pronounced in individuals with frequent chocolate cravings. In the current study, neural and cognitive correlates of chocolate thought suppression were investigated as a function of trait chocolate craving. Specifically, 20 high and 20 low trait chocolate cravers followed suppression vs. free thinking instructions after being exposed to chocolate and neutral images. Enhanced cue reactivity was evident in high trait chocolate cravers in that they reported more chocolate-related thoughts selectively after chocolate images compared to their low trait craving counterparts. This cue reactivity was mirrored neurally by higher activation in the ventral and dorsal striatum, demonstrating enhanced reward system activity. Unexpectedly, high trait chocolate cravers successfully reduced their elevated chocolate thoughts in the suppression condition. This lends support for the use of thought suppression as a means of regulating unwanted thoughts, cravings and imagery. Whether this thought manipulation is able to curb the elevated cue reactivity and the underlying reward sensitivity in chocolate cravers in applied settings remains to be shown. Copyright © 2018 Elsevier Ltd. All rights reserved.

  10. Industrial demonstration trials

    International Nuclear Information System (INIS)

    Gelee, M.; Fabre, C.; Villepoix, R. de; Fra, J.; Le Foulgoc, L.; Morel, Y.; Querite, P.; Roques, R.

    1975-01-01

    Prototypes of the plant components, meeting the specifications set by the process and built by industrial firms in collaboration with the supervisor and the C.E.A., are subjected to trial runs on the UF 6 test bench of the Pierrelatte testing zone. These items of equipment (diffuser, compressor, exchanger) are placed in an industrial operation context very similar to that of an enrichment plant. Their performance is measured within a broad region around the working point and their reliability observed over periods up to several tens of thousands of hours. Between 1969 and 1973 six industrial demonstration test benches have been built, marking the stages in the technical preparation of the 1973 file on the basis of which the decision of building was taken by Eurodif [fr

  11. Fusion Power Demonstration III

    International Nuclear Information System (INIS)

    Lee, J.D.

    1985-07-01

    This is the third in the series of reports covering the Fusion Power Demonstration (FPD) design study. This volume considers the FPD-III configuration that incorporates an octopole end plug. As compared with the quadrupole end-plugged designs of FPD-I and FPD-II, this octopole configuration reduces the number of end cell magnets and shortens the minimum ignition length of the central cell. The end-cell plasma length is also reduced, which in turn reduces the size and cost of the end cell magnets and shielding. As a contiuation in the series of documents covering the FPD, this report does not stand alone as a design description of FPD-III. Design details of FPD-III subsystems that do not differ significantly from those of the FPD-II configuration are not duplicated in this report

  12. TPA device for demonstration

    International Nuclear Information System (INIS)

    1980-02-01

    The TPA (torus plasma for amature) is a small race-trac type device made by the technical service division to demonstrate basic properties of plasma such as electron temperature, conductivity, effect of helical field for toroidal drift, and shape of plasma in mirror and cusp magnetic field in linear section. The plasmas are produced by RF discharge (-500W) and/or DC discharge (-30 mA) within glass discharge tube. Where major radius is 50 cm, length of linear section is 50 cm, toroidal magnetic field is 200 gauss. The device has been designed to be compact with only 100 V power source (-3.2 KW for the case without helical field) and to be full automatic sequence of operation. (author)

  13. Dynamic wall demonstration project

    Energy Technology Data Exchange (ETDEWEB)

    Nakatsui, L.; Mayhew, W.

    1990-12-01

    The dynamic wall concept is a ventilation strategy that can be applied to a single family dwelling. With suitable construction, outside air can be admitted through the exterior walls of the house to the interior space to function as ventilation air. The construction and performance monitoring of a demonstration house built to test the dynamic wall concept in Sherwood Park, Alberta, is described. The project had the objectives of demonstrating and assessing the construction methods; determining the cost-effectiveness of the concept in Alberta; analyzing the operation of the dynamic wall system; and determining how other components and systems in the house interact with the dynamic wall. The exterior wall construction consisted of vinyl siding, spun-bonded polyolefin-backed (SBPO) rigid fiberglass sheathing, 38 mm by 89 mm framing, fiberglass batt insulation and 12.7 mm drywall. The mechanical system was designed to operate in the dynamic (negative pressure) mode, however flexibility was provided to allow operation in the static (balanced pressure) mode to permit monitoring of the walls as if they were in a conventional house. The house was monitored by an extensive computerized monitoring system. Dynamic wall operation was dependent on pressure and temperature differentials between indoor and outdoor as well as wind speed and direction. The degree of heat gain was found to be ca 74% of the indoor-outdoor temperature differential. Temperature of incoming dynamic air was significantly affected by solar radiation and measurement of indoor air pollutants found no significant levels. 4 refs., 34 figs., 11 tabs.

  14. High Dietary Fructose Intake on Cardiovascular Disease Related Parameters in Growing Rats.

    Science.gov (United States)

    Yoo, SooYeon; Ahn, Hyejin; Park, Yoo Kyoung

    2016-12-26

    The objective of this study was to determine the effects of a high-fructose diet on cardiovascular disease (CVD)-related parameters in growing rats. Three-week-old female Sprague Dawley rats were randomly assigned to four experimental groups; a regular diet group (RD: fed regular diet based on AIN-93G, n = 8), a high-fructose diet group (30Frc: fed regular diet with 30% fructose, n = 8), a high-fat diet group (45Fat: fed regular diet with 45 kcal% fat, n = 8) or a high fructose with high-fat diet group (30Frc + 45Fat, fed diet 30% fructose with 45 kcal% fat, n = 8). After an eight-week treatment period, the body weight, total-fat weight, serum glucose, insulin, lipid profiles and pro-inflammatory cytokines, abdominal aortic wall thickness, and expressions of eNOS and ET-1 mRNA were analyzed. The result showed that total-fat weight was higher in the 30Frc, 45Fat, and 30Frc + 45Fat groups compared to the RD group ( p fructose consumption and high fat consumption in growing rats had similar negative effects on CVD-related parameters.

  15. DRD4 long allele carriers show heightened attention to high-priority items relative to low-priority items.

    Science.gov (United States)

    Gorlick, Marissa A; Worthy, Darrell A; Knopik, Valerie S; McGeary, John E; Beevers, Christopher G; Maddox, W Todd

    2015-03-01

    Humans with seven or more repeats in exon III of the DRD4 gene (long DRD4 carriers) sometimes demonstrate impaired attention, as seen in attention-deficit hyperactivity disorder, and at other times demonstrate heightened attention, as seen in addictive behavior. Although the clinical effects of DRD4 are the focus of much work, this gene may not necessarily serve as a "risk" gene for attentional deficits, but as a plasticity gene where attention is heightened for priority items in the environment and impaired for minor items. Here we examine the role of DRD4 in two tasks that benefit from selective attention to high-priority information. We examine a category learning task where performance is supported by focusing on features and updating verbal rules. Here, selective attention to the most salient features is associated with good performance. In addition, we examine the Operation Span (OSPAN) task, a working memory capacity task that relies on selective attention to update and maintain items in memory while also performing a secondary task. Long DRD4 carriers show superior performance relative to short DRD4 homozygotes (six or less tandem repeats) in both the category learning and OSPAN tasks. These results suggest that DRD4 may serve as a "plasticity" gene where individuals with the long allele show heightened selective attention to high-priority items in the environment, which can be beneficial in the appropriate context.

  16. Radionuclide accumulation peculiarities demonstrated by vegetable varieties

    International Nuclear Information System (INIS)

    Kruk, A.V.; Goncharenko, G.G.; Kilchevsky, A.V.

    2004-01-01

    This study focused on ecological and genetic aspects of radionuclide accumulation demonstrated by a number of vegetable varieties. The researches resulted in determining the cabbage varieties which were characterised by the minimal level of radionuclide accumulation. It was shown that the above varieties manifested the relation between radionuclide accumulation and morphobiological characteristics such as vegetation period duration and yield criteria. The study specified the genotypes with high ecological stability as regards to radionuclide accumulation: 'Beloruskaya 85' cabbage and 'Dokhodny' tomato showed the best response to Cs 137, while 'Beloruskaya 85', 'Rusinovka', 'Amager 611' cabbage varieties and 'Sprint' tomato showed the minimal level of Sr 90 accumulation. (authors)

  17. Highly cited articles in wind tunnel-related research: a bibliometric analysis.

    Science.gov (United States)

    Mo, Ziwei; Fu, Hui-Zhen; Ho, Yuh-Shan

    2018-03-22

    Wind tunnels have been widely employed in aerodynamic research. To characterize the high impact research, a bibliometric analysis was conducted on highly cited articles related to wind tunnel based on the Science Citation Index Expanded (SCI-EXPANDED) database from 1900 to 2014. Articles with at least 100 citations from the Web of Science Core Collection were selected and analyzed in terms of publication years, authors, institutions, countries/territories, journals, Web of Science categories, and citation life cycles. The results show that a total of 77 highly cited articles in 37 journals were published between 1959 and 2008. Journal of Fluid Mechanics published the most of highly cited articles. The USA was the most productive country and most frequent partner of internationally collaboration. The prolific institutions were mainly located in the USA and UK. The authors who were both first author and corresponding author published 88% of the articles. The Y index was also deployed to evaluate the publication characteristics of authors. Moreover, the articles with high citations in both history and the latest year with their citation life cycles were examined to provide insights for high impact research. The highly cited articles were almost earliest wind tunnel experimental data and reports on their own research specialty, and thus attracted high citations. It was revealed that classic works of wind tunnel research was frequently occurred in 1990s but much less in 2000s, probably due to the development of numerical models of computational fluid dynamic (CFD) in recent decades.

  18. Factors related to cancer information scanning and seeking behavior among high school students in Korea.

    Science.gov (United States)

    Kye, Su Yeon; Yun, E Hwa; Park, Keeho

    2012-01-01

    This paper aimed to determine the relationship between cancer information scanning and seeking experience of adolescents and cancer preventive behavior, perceived cancer risk, and levels of cancer- related knowledge. The study sample comprised 1,000 second-year students from 6 high schools: the general and vocational school systems were each represented by 1 boys', 1 girls', and 1 coeducational high school. In July 2011, trained researchers visited each classroom, explained the purpose of the study, distributed questionnaires to the students who agreed to participate, instructed them to complete the survey by self-reporting, and collected the completed questionnaires. The students who attended general high schools (as compared with vocational high schools), earned higher grades, consumed more vegetables, had a higher perceived cancer risk, and answered the cancer-related questions more correctly and had more cancer information scanning and seeking experience. These results reinforce the importance of cancer prevention health education. Furthermore, the results may help in preparing a strategy that enables people to acquire accurate cancer-related information easily and quickly.

  19. Assessment and management of sport-related concussions in United States high schools.

    Science.gov (United States)

    Meehan, William P; d'Hemecourt, Pierre; Collins, Christy L; Comstock, R Dawn

    2011-11-01

    Little existing data describe which medical professionals and which medical studies are used to assess sport-related concussions in high school athletes. To describe the medical providers and medical studies used when assessing sport-related concussions. To determine the effects of medical provider type on timing of return to play, frequency of imaging, and frequency of neuropsychological testing. Descriptive epidemiology study. All concussions recorded by the High School Reporting Information Online (HS RIO) injury surveillance system during the 2009 to 2010 academic year were included. χ(2) analyses were conducted for categorical variables. Fisher exact test was used for nonparametric data. Logistic regression analyses were used when adjusting for potential confounders. Statistical significance was considered for P sport-related concussions, representing 14.6% of all injuries. Most (94.4%) concussions were assessed by athletic trainers (ATs), 58.8% by a primary care physician. Few concussions were managed by specialists. The assessment of 21.2% included computed tomography. Computerized neuropsychological testing was used for 41.2%. For 50.1%, a physician decided when to return the athlete to play; for 46.2%, the decision was made by an AT. After adjusting for potential confounders, no associations between timing of return to play and the type of provider (physician vs AT) deciding to return the athlete to play were found. Concussions account for nearly 15% of all sport-related injuries in high school athletes. The timing of return to play after a sport-related concussion is similar regardless of whether the decision to return the athlete to play is made by a physician or an AT. When a medical doctor is involved, most concussions are assessed by primary care physicians as opposed to subspecialists. Computed tomography is obtained during the assessment of 1 of every 5 concussions occurring in high school athletes.

  20. Small demonstration HTGR concept

    International Nuclear Information System (INIS)

    Kiryushin, A.I.

    1989-01-01

    Currently the USSR is investigating two high-temperature gas-cooled reactors. The first plant is the VGM, a modular type HTGR with power rating of 180-250 MWth. The second plant is the VG-400 with 1000 MWth and a prestressed concrete reactor vessel. The paper contains the description of the VGM design and its main components. (author). 1 fig., 1 tab

  1. Reference satellite selection method for GNSS high-precision relative positioning

    Directory of Open Access Journals (Sweden)

    Xiao Gao

    2017-03-01

    Full Text Available Selecting the optimal reference satellite is an important component of high-precision relative positioning because the reference satellite directly influences the strength of the normal equation. The reference satellite selection methods based on elevation and positional dilution of precision (PDOP value were compared. Results show that all the above methods cannot select the optimal reference satellite. We introduce condition number of the design matrix in the reference satellite selection method to improve structure of the normal equation, because condition number can indicate the ill condition of the normal equation. The experimental results show that the new method can improve positioning accuracy and reliability in precise relative positioning.

  2. Triton-3He relative and differential flows and the high density behavior of nuclear symmetry

    International Nuclear Information System (INIS)

    Yong, Gaochan; Li, Baoan; Chen, Liewen

    2010-01-01

    Using a transport model coupled with a phase-space coalescence after-burner we study the triton- 3 He relative and differential transverse flows in semi-central 132 Sn + 124 Sn reactions at a beam energy of 400 MeV/nucleon. We find that the triton- 3 He pairs carry interesting information about the density dependence of the nuclear symmetry energy. The t- 3 He relative flow can be used as a particularly powerful probe of the high-density behavior of the nuclear symmetry energy. (author)

  3. Comparative performance measures of relational and object-oriented databases using High Energy Physics data

    International Nuclear Information System (INIS)

    Marstaller, J.

    1993-12-01

    The major experiments at the SSC are expected to produce up to 1 Petabyte of data per year. The use of database techniques can significantly reduce the time it takes to access data. The goal of this project was to test which underlying data model, the relational or the object-oriented, would be better suited for archival and accessing high energy data. We describe the relational and the object-oriented data model and their implementation in commercial database management systems. To determine scalability we tested both implementations for 10-MB and 100-MB databases using storage and timing criteria

  4. Affect of school related factors in the student's choices of the high school

    OpenAIRE

    Gönül Cengiz; Osman Titrek; Özcan Erkan Akgün

    2007-01-01

    It is studied that to determine the school related factors which affects the students’ choices of the high school, according to the type of the schools. This is a survey study. The participants are 523  9 th grade students in 21 secondary schools in Adapazarı. SPSS is used for analyzing data. Kay-Kare Test is used to determine the demografic differences due to the type of the school. To analyze the data for the school related factors, Kruskal Wallis is used. As a result, it is expr...

  5. A Demonstration of Lusail

    KAUST Repository

    Mansour, Essam; Abdelaziz, Ibrahim; Ouzzani, Mourad; Aboulnaga, Ashraf; Kalnis, Panos

    2017-01-01

    There has been a proliferation of datasets available as interlinked RDF data accessible through SPARQL endpoints. This has led to the emergence of various applications in life science, distributed social networks, and Internet of Things that need to integrate data from multiple endpoints. We will demonstrate Lusail; a system that supports the need of emerging applications to access tens to hundreds of geo-distributed datasets. Lusail is a geo-distributed graph engine for querying linked RDF data. Lusail delivers outstanding performance using (i) a novel locality-aware query decomposition technique that minimizes the intermediate data to be accessed by the subqueries, and (ii) selectivityawareness and parallel query execution to reduce network latency and to increase parallelism. During the demo, the audience will be able to query actually deployed RDF endpoints as well as large synthetic and real benchmarks that we have deployed in the public cloud. The demo will also show that Lusail outperforms state-of-the-art systems by orders of magnitude in terms of scalability and response time.

  6. A Demonstration of Lusail

    KAUST Repository

    Mansour, Essam

    2017-05-10

    There has been a proliferation of datasets available as interlinked RDF data accessible through SPARQL endpoints. This has led to the emergence of various applications in life science, distributed social networks, and Internet of Things that need to integrate data from multiple endpoints. We will demonstrate Lusail; a system that supports the need of emerging applications to access tens to hundreds of geo-distributed datasets. Lusail is a geo-distributed graph engine for querying linked RDF data. Lusail delivers outstanding performance using (i) a novel locality-aware query decomposition technique that minimizes the intermediate data to be accessed by the subqueries, and (ii) selectivityawareness and parallel query execution to reduce network latency and to increase parallelism. During the demo, the audience will be able to query actually deployed RDF endpoints as well as large synthetic and real benchmarks that we have deployed in the public cloud. The demo will also show that Lusail outperforms state-of-the-art systems by orders of magnitude in terms of scalability and response time.

  7. Demonstration exercise 'Cavtat 09'

    International Nuclear Information System (INIS)

    Trut, D.

    2009-01-01

    The demonstration exercise is to show a terrorist attack in urban area resulting in a certain number of injured people. On 7th April 2009 a terrorist group HAL 9000 is in Cavtat and set up an explosive devices with chemical reagents in several spots with intention to activate them and cause great number of victims. On the same day, in area of the Cavtat Croatia Hotel, which is hosting the world CBMTS Congress, Cavtat Police Station notice several masked persons, in escapement. Hotel personnel alerted the County 112 Center about noticed devices placed by chlorine dioxide tanks, for water conditioning. Intervention police came to block entrance to this area and evacuate hotel's guests and congress members. An explosion and fire occurs from where the position of water-conditioning plant and chlorine dioxide tank. The 112 Center alarms fire-fighters for fight fire and decontamination action and HAZMAT Civil Support Team from Georgia (participated the congress). In the meantime, guests have been instructed not to leave their rooms and to hermetically close doors and windows with available material to keep away potential toxic fume. Decision makers form the County Protection and Rescue Headquarters monitors the situation till the end of alert for the population in the area of Cavtat.(author)

  8. Tidd PFBC demonstration project

    Energy Technology Data Exchange (ETDEWEB)

    Marrocco, M. [American Electric Power, Columbus, OH (United States)

    1997-12-31

    The Tidd project was one of the first joint government-industry ventures to be approved by the US Department of Energy (DOE) in its Clean Coal Technology Program. In March 1987, DOE signed an agreement with the Ohio Power Company, a subsidiary of American Electric Power, to refurbish the then-idle Tidd plant on the banks of the Ohio River with advanced pressurized fluidized bed technology. Testing ended after 49 months of operation, 100 individual tests, and the generation of more than 500,000 megawatt-hours of electricity. The demonstration plant has met its objectives. The project showed that more than 95 percent of sulfur dioxide pollutants could be removed inside the advanced boiler using the advanced combustion technology, giving future power plants an attractive alternative to expensive, add-on scrubber technology. In addition to its sulfur removal effectiveness, the plant`s sustained periods of steady-state operation boosted its availability significantly above design projections, heightening confidence that pressurized fluidized bed technology will be a reliable, baseload technology for future power plants. The technology also controlled the release of nitrogen oxides to levels well below the allowable limits set by federal air quality standards. It also produced a dry waste product that is much easier to handle than wastes from conventional power plants and will likely have commercial value when produced by future power plants.

  9. Prevalence of Facebook Addiction and Related Factors Among Thai High School Students.

    Science.gov (United States)

    Khumsri, Jiraporn; Yingyeun, Rungmanee; Mereerat Manwong; Hanprathet, Nitt; Phanasathit, Muthita

    2015-04-01

    To determine the prevalence ofFacebook (FB) addiction and its related factors among Thai high school students. This cross-sectional study was performed among 972 high school students in four provinces associated with high economic prosperity in Thailand: Bangkok, Ubon Ratchathani, Chiang Mai and Songkhla, utilizing a multistage cluster sampling technique. A self-administrative questionnaire was produced composing of three parts; demographic data, a Thai version of the Bergen Facebook Addiction Scale (Thai-BFAS) and the Thai version of the General Health Questionnaire-28 items. Multivariate analysis was employed to analyze thefactors associated with FB addiction. The prevalence ofFB addiction amongst Thai adolescents was 41.8% (95% CI; 38.6, 45.2). Related factors included gender school location, sufficiency ofpersonalfinance, devices ofFB access, duration ofstaying online via FB, andFB usage during holidays. In addition, every 1-hour increase in usage enhanced the risk for FB addiction (OR = 1.12, 95% CI; 1.05, 1.19). The prevalence of FB addiction in Thai high school students was found to be higher than in many other countries. Relatedfactors should be controlled in order to reduce FB addiction and its detrimental impacts, such as behavior modification and the promotion of healthier free-time activities. Further studies are recommended to understand why FB addiction is so high in Thailand.

  10. Relative chronology in high-grade crystalline terrain of the Eastern Ghats, India: new insights

    Science.gov (United States)

    Bhattacharya, S.; Kar, R.; Saw, A. K.; Das, P.

    2011-01-01

    The two major lithology or gneiss components in the polycyclic granulite terrain of the Eastern Ghats, India, are the supracrustal rocks, commonly described as khondalites, and the charnockite-gneiss. Many of the workers considered the khondalites as the oldest component with unknown basement and the charnockite-protoliths as intrusive into the khondalites. However, geochronological data do not corroborate the aforesaid relations. The field relations of the hornblende- mafic granulite with the two gneiss components together with geocronological data indicate that khondalite sediments were deposited on older mafic crustal rocks. We propose a different scenario: Mafic basement and supracrustal rocks were subsequently deformed and metamorphosed together at high to ultra-high temperatures - partial melting of mafic rocks producing the charnockitic melt; and partial melting of pelitic sediments producing the peraluminous granitoids. This is compatible with all the geochronological data as well as the petrogenetic model of partial melting for the charnockitic rocks in the Eastern Ghats Belt.

  11. E/Z MAS demonstration

    International Nuclear Information System (INIS)

    Boor, M.G.; Hurford, J.M.; Landry, R.P.; Martinez, B.J.; Solem, A.M.; Whiteson, R.; Zardecki, A.

    1998-01-01

    Los Alamos National Laboratory has developed E/Z MAS, a new generation nuclear material accountability application based on the latest technology and designed for facilities required to track nuclear materials with a simple-to-use interface. E/Z MAS is based on years of experience spent developing nuclear material accounting systems. E/Z MAS uses a modern relational database with a web server and enables users on a classified local area network to interact with the database with web browsers. The E/Z MAS Demonstration poster session demonstrates the E/Z MAS functions required by an operational nuclear facility to track material as it enters and leaves a facility and to account for the material as it moves through a process. The generation of internal facility reports and external reports for the Russian Federal system will be demonstrated. Bar-code readers will be used to demonstrate the ability of EZ MAS to automate certain functions, such as physical inventories at facilities

  12. Relativity

    CERN Document Server

    Einstein, Albert

    2013-01-01

    Time magazine's ""Man of the Century"", Albert Einstein is the founder of modern physics and his theory of relativity is the most important scientific idea of the modern era. In this short book, Einstein explains, using the minimum of mathematical terms, the basic ideas and principles of the theory that has shaped the world we live in today. Unsurpassed by any subsequent books on relativity, this remains the most popular and useful exposition of Einstein's immense contribution to human knowledge.With a new foreword by Derek Raine.

  13. Hypercalcemia and high parathyroid hormone-related protein concentration associated with malignant melanoma in a dog.

    Science.gov (United States)

    Pressler, Barrak M; Rotstein, David S; Law, Jerry M; Rosol, Thomas J; LeRoy, Bruce; Keene, Bruce W; Jackson, Mark W

    2002-07-15

    A 12-year-old Cocker Spaniel with an oral malignant melanoma was evaluated for progressive lethargy and anorexia. No metastases were identified during antemortem evaluation, but severe hypercalcemia was evident. Antemortem diagnostic testing failed to identify a cause for the hypercalcemia. No neoplasms other than the melanoma were identified on postmortem examination. Serum parathyroid hormone-related protein concentration was markedly high, and the melanoma had moderate to marked immunostaining for this protein. Paraneoplastic syndromes are rare in dogs with malignant melanoma.

  14. The Relation between Reflection-Impulsivity and Perceived Competence in Junior High School Children

    OpenAIRE

    桜井, 茂男

    1990-01-01

    The purpose of this study was to investigate the relation between perceived competence and reflection-impulsivity in junior high school students. Two scales, i. e. , the Perceived Competence Scale for Children developed by Sakurai (1983) and the Matching Familiar Figures (MFF) test developed by Sugihara (1977) , were administrated to 70 eighth male students and 70 eighth female students. The performance, Impulsivity (I) score, and Efficiency (E) score (see Salkind & Wright, 1977) in MFF test ...

  15. Work Sectors with High Risk for Work-Related Musculoskeletal Disorders in Korean Men and Women

    OpenAIRE

    Jungsun Park; Yangho Kim; Boyoung Han

    2018-01-01

    Background: To identify work sectors with high risk for work-related musculoskeletal disorders (MSDs) in Korean men and women. Methods: We analyzed nationwide data to identify ergonomic risk factors in Korean employees. In particular, we analyzed data on exposure to five ergonomic risk factors (painful/tiring postures, lifting/moving heavy materials, standing/walking, repetitive hand/arm movements, and hand/arm vibration) according to employment sector, sex, and age, using the 2014 Fourth Kor...

  16. Assessment and Management of Sport-Related Concussions in United States High Schools

    Science.gov (United States)

    Meehan, William P.; d’Hemecourt, Pierre; Collins, Christy L.; Comstock, R. Dawn

    2012-01-01

    Background Little existing data describe which medical professionals and which medical studies are used to assess sport-related concussions in high school athletes. Purpose To describe the medical providers and medical studies used when assessing sport-related concussions. To determine the effects of medical provider type on timing of return to play, frequency of imaging, and frequency of neuropsychological testing. Study Design Descriptive epidemiology study. Methods All concussions recorded by the High School Reporting Information Online (HS RIO) injury surveillance system during the 2009 to 2010 academic year were included. χ2 analyses were conducted for categorical variables. Fisher exact test was used for nonparametric data. Logistic regression analyses were used when adjusting for potential confounders. Statistical significance was considered for P concussions, representing 14.6% of all injuries. Most (94.4%) concussions were assessed by athletic trainers (ATs), 58.8% by a primary care physician. Few concussions were managed by specialists. The assessment of 21.2% included computed tomography. Computerized neuropsychological testing was used for 41.2%. For 50.1%, a physician decided when to return the athlete to play; for 46.2%, the decision was made by an AT. After adjusting for potential confounders, no associations between timing of return to play and the type of provider (physician vs AT) deciding to return the athlete to play were found. Conclusion Concussions account for nearly 15% of all sport-related injuries in high school athletes. The timing of return to play after a sport-related concussion is similar regardless of whether the decision to return the athlete to play is made by a physician or an AT. When a medical doctor is involved, most concussions are assessed by primary care physicians as opposed to subspecialists. Computed tomography is obtained during the assessment of 1 of every 5 concussions occurring in high school athletes. PMID:21969181

  17. CALDERON COKEMAKING PROCESS/DEMONSTRATION PROJECT

    International Nuclear Information System (INIS)

    Albert Calderon

    1999-01-01

    This project deals with the demonstration of a coking process using proprietary technology of Calderon, with the following objectives geared to facilitate commercialization: (1) making coke of such quality as to be suitable for use in hard-driving, large blast furnaces; (2) providing proof that such process is continuous and environmentally closed to prevent emissions; (3) demonstrating that high-coking-pressure (non-traditional) coal blends which cannot be safely charged into conventional by-product coke ovens can be used in the Calderon process; and (4) demonstrating that coke can be produced economically, at a level competitive with coke imports. The activities of the past quarter were focused on the following: Consolidation of the team of stakeholders; Move the site for the commercial demonstration to LTV Steel, Cleveland, Ohio; Permitting for new site; Site specific engineering; Cost update of the project as it relates to the Cleveland location; FETC update; DCAA audit; and Updated endorsement of Calderon process by Ohio EPA and U.S. EPA, Region 5

  18. Experimental and Numerical Investigation of Thermoacoustic Sources Related to High-Frequency Instabilities

    Directory of Open Access Journals (Sweden)

    Mathieu Zellhuber

    2014-03-01

    Full Text Available Flame dynamics related to high-frequency instabilities in gas turbine combustors are investigated using experimental observations and numerical simulations. Two different combustor types are studied, a premix swirl combustor (experiment and a generic reheat combustor (simulation. In both cases, a very similar dynamic behaviour of the reaction zone is observed, with the appearance of transverse displacement and coherent flame wrinkling. From these observations, a model for the thermoacoustic feedback linked to transverse modes is proposed. The model splits heat release rate fluctuations into distinct contributions that are related to flame displacement and variations of the mass burning rate. The decomposition procedure is applied on the numerical data and successfully verified by comparing a reconstructed Rayleigh index with the directly computed value. It thus allows to quantify the relative importance of various feedback mechanisms for a given setup.

  19. Individual differences at high perceptual load: the relation between trait anxiety and selective attention.

    Science.gov (United States)

    Sadeh, Naomi; Bredemeier, Keith

    2011-06-01

    Attentional control theory (Eysenck et al., 2007) posits that taxing attentional resources impairs performance efficiency in anxious individuals. This theory, however, does not explicitly address if or how the relation between anxiety and attentional control depends upon the perceptual demands of the task at hand. Consequently, the present study examined the relation between trait anxiety and task performance using a perceptual load task (Maylor & Lavie, 1998). Sixty-eight male college students completed a visual search task that indexed processing of irrelevant distractors systematically across four levels of perceptual load. Results indicated that anxiety was related to difficulty suppressing the behavioural effects of irrelevant distractors (i.e., decreased reaction time efficiency) under high, but not low, perceptual loads. In contrast, anxiety was not associated with error rates on the task. These findings are consistent with the prediction that anxiety is associated with impairments in performance efficiency under conditions that tax attentional resources.

  20. Health-related quality of life in patients with high-grade gliomas

    DEFF Research Database (Denmark)

    Piil, K; Jakobsen, J; Christensen, Karl Bang

    2015-01-01

    follow-up after 1 year. Scores of Karnofsky Performance Status (KPS), physical activity, anxiety and depression and health-related quality of life (FACT-Br) are obtained. Patients' physical activity level and KPS decrease during the disease- and treatment trajectory. The majority of patients did......The diagnosis of a high-grade glioma usual is followed by functional impairment(s), cognitive decline and an impaired psycho-social well-being. This might well have a significant and negative impact on the health related quality of life. The purpose of this study was to explore physical activity...... levels, prevalence and severity of anxiety and depressive symptoms and health-related quality of life among patients with a highgrade glioma. This paper is based on a longitudinal mixed methods study. Patients (n = 30) completed questionnaires at 5 time points from time of diagnosis until the final...

  1. Measurement of the positron-drift time relation of a high-pressure drift chamber

    International Nuclear Information System (INIS)

    Pruefert, W.

    1989-04-01

    As a test of its performance, the measurement of the drift time versus drift distance relation of a high pressure drift chamber using cosmic rays is described. Two multiwire proportional chambers, mounted above and below the detector, are used to define the track of the cosmic particle in the drift chamber. The drift chamber is read out by FADCs (Flash Analog to Digital Converter), and the drift time is determined from the FADC signals by the DOS- (Difference Of Samples) method. The measured drift time versus drift distance relation showed good agreement with the relation, which is expected from the spatial dependence of the electric field and the dependence of the drift velocity on this field. (orig.) [de

  2. Relative variations of gut microbiota in disordered cholesterol metabolism caused by high-cholesterol diet and host genetics.

    Science.gov (United States)

    Bo, Tao; Shao, Shanshan; Wu, Dongming; Niu, Shaona; Zhao, Jiajun; Gao, Ling

    2017-08-01

    Recent studies performed provide mechanistic insight into effects of the microbiota on cholesterol metabolism, but less focus was given to how cholesterol impacts the gut microbiota. In this study, ApoE -/- Sprague Dawley (SD) rats and their wild-type counterparts (n = 12) were, respectively, allocated for two dietary condition groups (normal chow and high-cholesterol diet). Total 16S rDNA of fecal samples were extracted and sequenced by high-throughput sequencing to determine differences in microbiome composition. Data were collected and performed diversity analysis and phylogenetic analysis. The influence of cholesterol on gut microbiota was discussed by using cholesterol dietary treatment as exogenous cholesterol disorder factor and genetic modification as endogenous metabolic disorder factor. Relative microbial variations were compared to illustrate the causality and correlation of cholesterol and gut microbiota. It turned out comparing to genetically modified rats, exogenous cholesterol intake may play more effective role in changing gut microbiota profile, although the serum cholesterol level of genetically modified rats was even higher. Relative abundance of some representative species showed that the discrepancies due to dietary variation were more obvious, whereas some low abundance species changed because of genetic disorders. Our results partially demonstrated that gut microbiota are relatively more sensitive to dietary variation. Nevertheless, considering the important effect of bacteria in cholesterol metabolism, the influence to gut flora by "genetically caused cholesterol disorder" cannot be overlooked. Manipulation of gut microbiota might be an effective target for preventing cholesterol-related metabolic disorders. © 2017 The Authors. MicrobiologyOpen published by John Wiley & Sons Ltd.

  3. Sports-related injuries among high school athletes--United States, 2005-06 school year.

    Science.gov (United States)

    2006-09-29

    Participation in high school sports helps promote a physically active lifestyle. High school sports participation has grown from an estimated 4 million participants during the 1971-72 school year to an estimated 7.2 million in 2005-06. However, despite the documented health benefits of increased physical activity (e.g., weight management, improved self-esteem, and increased strength, endurance, and flexibility), those who participate in athletics are at risk for sports-related injuries. High school athletes account for an estimated 2 million injuries, 500,000 doctor visits, and 30,000 hospitalizations annually. To date, the study of these injuries has been limited by inabilities to calculate injury rates, compare results among groups, and generalize findings from small, nonrepresentative samples. During the 2005-06 school year, researchers at a children's hospital in Ohio used an Internet-based data-collection tool to pilot an injury surveillance system among athletes from a representative national sample of U.S. high schools. This report summarizes the findings of that study, which indicated that participation in high school sports resulted in an estimated 1.4 million injuries at a rate of 2.4 injuries per 1,000 athlete exposures (i.e., practices or competitions). Surveillance of exposure-based injury rates in a nationally representative sample of high school athletes and analysis of injury patterns can help guide activities aimed at reducing these injuries.

  4. Advanced technologies related to a high temperature superconductor for small laboratory experiments

    International Nuclear Information System (INIS)

    Ogawa, Yuichi; Mito, Toshiyuki; Yanagi, Nagato

    2006-01-01

    Advanced technologies related to a high temperature superconductor materials and small refrigerator are reviewed. Mini-RT/RT-1 is designed and constructed as a plasma examination device. The element technology of low temperature apparatus, the results of performance tests and application examples are explained. The superconductors such as Bi 2 Sr 2 CaCu 2 O 8 (Bi-2212) for the low temperature phase, Bi 2 Sr 2 Ca 2 Cu 3 O 10 (Bi-2223) for the high temperature phase, and YBa 2 Cu 3 O y (YBCO or Y123) are described. Advanced 4K-Giford-Mcmahon (GM) refrigerator on the market put superconductor coil made of low temperature superconductor metals to practical use and extends its application field. Small laboratory is able to experiment on the high temperature superconductor materials. (S.Y.)

  5. What's Past is Prologue: Relations Between Early Mathematics Knowledge and High School Achievement.

    Science.gov (United States)

    Watts, Tyler W; Duncan, Greg J; Siegler, Robert S; Davis-Kean, Pamela E

    2014-10-01

    Although previous research has established the association between early-grade mathematics knowledge and later mathematics achievement, few studies have measured mathematical skills prior to school entry, nor have they investigated the predictive power of early gains in mathematics ability. The current paper relates mathematical skills measured at 54 months to adolescent mathematics achievement using multi-site longitudinal data. We find that preschool mathematics ability predicts mathematics achievement through age 15, even after accounting for early reading, cognitive skills, and family and child characteristics. Moreover, we find that growth in mathematical ability between age 54 months and first grade is an even stronger predictor of adolescent mathematics achievement. These results demonstrate the importance of pre-kindergarten mathematics knowledge and early math learning for later achievement.

  6. What’s Past is Prologue: Relations Between Early Mathematics Knowledge and High School Achievement

    Science.gov (United States)

    Watts, Tyler W.; Duncan, Greg J.; Siegler, Robert S.; Davis-Kean, Pamela E.

    2015-01-01

    Although previous research has established the association between early-grade mathematics knowledge and later mathematics achievement, few studies have measured mathematical skills prior to school entry, nor have they investigated the predictive power of early gains in mathematics ability. The current paper relates mathematical skills measured at 54 months to adolescent mathematics achievement using multi-site longitudinal data. We find that preschool mathematics ability predicts mathematics achievement through age 15, even after accounting for early reading, cognitive skills, and family and child characteristics. Moreover, we find that growth in mathematical ability between age 54 months and first grade is an even stronger predictor of adolescent mathematics achievement. These results demonstrate the importance of pre-kindergarten mathematics knowledge and early math learning for later achievement. PMID:26806961

  7. 40 CFR 117.14 - Demonstration projects.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 21 2010-07-01 2010-07-01 false Demonstration projects. 117.14 Section... DETERMINATION OF REPORTABLE QUANTITIES FOR HAZARDOUS SUBSTANCES Applicability § 117.14 Demonstration projects... research or demonstration projects relating to the prevention, control, or abatement of hazardous substance...

  8. Validation of visualized transgenic zebrafish as a high throughput model to assay bradycardia related cardio toxicity risk candidates.

    Science.gov (United States)

    Wen, Dingsheng; Liu, Aiming; Chen, Feng; Yang, Julin; Dai, Renke

    2012-10-01

    Drug-induced QT prolongation usually leads to torsade de pointes (TdP), thus for drugs in the early phase of development this risk should be evaluated. In the present study, we demonstrated a visualized transgenic zebrafish as an in vivo high-throughput model to assay the risk of drug-induced QT prolongation. Zebrafish larvae 48 h post-fertilization expressing green fluorescent protein in myocardium were incubated with compounds reported to induce QT prolongation or block the human ether-a-go-go-related gene (hERG) K⁺ current. The compounds sotalol, indapaminde, erythromycin, ofoxacin, levofloxacin, sparfloxacin and roxithromycin were additionally administrated by microinjection into the larvae yolk sac. The ventricle heart rate was recorded using the automatic monitoring system after incubation or microinjection. As a result, 14 out of 16 compounds inducing dog QT prolongation caused bradycardia in zebrafish. A similar result was observed with 21 out of 26 compounds which block hERG current. Among the 30 compounds which induced human QT prolongation, 25 caused bradycardia in this model. Thus, the risk of compounds causing bradycardia in this transgenic zebrafish correlated with that causing QT prolongation and hERG K⁺ current blockage in established models. The tendency that high logP values lead to high risk of QT prolongation in this model was indicated, and non-sensitivity of this model to antibacterial agents was revealed. These data suggest application of this transgenic zebrafish as a high-throughput model to screen QT prolongation-related cardio toxicity of the drug candidates. Copyright © 2012 John Wiley & Sons, Ltd.

  9. High-precision gravity measurements using absolute and relative gravimeters at Mount Etna (Sicily, Italy

    Directory of Open Access Journals (Sweden)

    Ciro Del Negro

    2011-12-01

    Full Text Available Accurate detection of time gravity changes attributable to the dynamics of volcanoes requires high-precision gravity measurements. With the aim of improving the quality of data from the Mount Etna gravity network, we used both absolute and relative gravimeters in a hybrid method. In this report, some of the techniques for gravity surveys are reviewed, and the results related to each method are compared. We show how the total uncertainty estimated for the gravity measurements performed with this combined use of absolute and relative gravimeters is roughly comparable to that calculated when the measurements are acquired using only relative gravimeters (the traditional method. However, the data highlight how the hybrid approach improves the measurement capabilities for surveying the Mount Etna volcanic area. This approach enhances the accuracy of the data, and then of the four-dimensional surveying, which minimizes ambiguities inherent in the gravity measurements. As a case study, we refer to two gravity datasets acquired in 2005 and 2010 from the western part of the Etna volcano, which included five absolute and 13 relative stations of the Etna gravity network.

  10. Plasma hearth process demonstration project

    International Nuclear Information System (INIS)

    Geimer, R.M.; Gillins, R.L.

    1995-01-01

    The Plasma Hearth Process (PHP) demonstration project is one of the key technology projects in the US Department of Energy (DOE) Office of Technology Development Mixed Waste Focus Area. The PHP is a high temperature thermal treatment process using a plasma arc torch in a stationary, refractory lined chamber that destroys organics and stabilizes the residuals in a nonleaching, vitrified waste form, greatly improving the disposability of the waste. This paper describes the PHP system and summarizes test results to date, including volume reduction, destruction and removal efficiencies for organic wastes, and emission characteristics. Tests performed so far demonstrate that the PHP adresses DOE mixed waste final waste form requirements and US Environmental Protection Agency Toxicity Characteristic Leaching Procedure requirements

  11. Subway-Related Trauma: An Urban Public Health Issue with a High Case-Fatality Rate.

    Science.gov (United States)

    Rodier, Simon G; DiMaggio, Charles J; Wall, Stephen; Sim, Vasiliy; Frangos, Spiros G; Ayoung-Chee, Patricia; Bukur, Marko; Tandon, Manish; Todd, S Rob; Marshall, Gary T

    2018-05-09

    Between 1990 and 2003, there were 668 subway-related fatalities in New York City. However, subway-related trauma remains an understudied area of injury-related morbidity and mortality. The objective of this study was to characterize the injuries and events leading up to the injuries of all patients admitted after subway-related trauma. We conducted a retrospective case series of subway-related trauma at a Level I trauma center from 2001 to 2016. Descriptive epidemiology of patient demographics, incident details, injuries, and outcomes were analyzed. Over 15 years, 254 patients were admitted for subway-related trauma. The mean (standard error of the mean) age was 41 (1.0) years, 80% were male (95% confidence interval [CI] 74-84%) and median Injury Severity Score was 14 (interquartile range [IQR] 5-24). The overall case-fatality rate was 10% (95% CI 7-15%). The most common injuries were long-bone fractures, intracranial hemorrhage, and traumatic amputations. Median length of stay was 6 days (IQR 1-18 days). Thirty-seven percent of patients required surgical intervention. At the time of injury, 55% of patients (95% CI 49-61%) had a positive urine drug or alcohol screen, 16% (95% CI 12-21%) were attempting suicide, and 39% (95% CI 33-45%) had a history of psychiatric illness. Subway-related trauma is associated with a high case-fatality rate. Alcohol or drug intoxication and psychiatric illness can increase the risk of this type of injury. Copyright © 2018 Elsevier Inc. All rights reserved.

  12. Contrasting dynamic spin susceptibility models and their relation to high-temperature superconductivity

    International Nuclear Information System (INIS)

    Schuettler, H.; Norman, M.R.

    1996-01-01

    We compare the normal-state resistivities ρ and the critical temperatures T c for superconducting d x 2 -y 2 pairing due to antiferromagnetic (AF) spin fluctuation exchange in the context of two phenomenological dynamical spin susceptibility models for the cuprate high-T c materials, one based on fits to NMR data on Y-Ba-Cu-O (YBCO) proposed by Millis, Monien, and Pines (MMP) and Monthoux and Pines (MP), and the other based on fits to neutron scattering data on YBCO proposed by Radtke, Ullah, Levin, and Norman (RULN). Assuming comparable electronic bandwidths and resistivities in both models, we show that the RULN model gives a much lower d-wave T c (approx-lt 20 K) than the MMP model (with T c ∼100 K). We demonstrate that these profound differences in the T c close-quote s arise from fundamental differences in the spectral weight distributions of the two model susceptibilities at high (>100 meV) frequencies and are not primarily caused by differences in the calculational techniques employed by MP and RULN. Further neutron scattering experiments, to explore the spectral weight distribution at all wave vectors over a sufficiently large excitation energy range, will thus be of crucial importance to resolve the question whether AF spin fluctuation exchange can provide a viable mechanism to account for high-T c superconductivity. Limitations of the Migdal-Eliashberg approach in such models will be discussed. copyright 1996 The American Physical Society

  13. Wind-related orientation patterns in diurnal, crepuscular and nocturnal high-altitude insect migrants

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    Gao eHu

    2016-02-01

    Full Text Available Most insect migrants fly at considerable altitudes (hundreds of meters above the ground where they utilize fast-flowing winds to achieve rapid and comparatively long-distance transport. The nocturnal aerial migrant fauna has been well studied with entomological radars, and many studies have demonstrated that flight orientations are frequently grouped around a common direction in a range of nocturnal insect migrants. Common orientation typically occurs close to the downwind direction (thus ensuring that a large component of the insects’ self-powered speed is directed downstream, and in nocturnal insects at least, the downwind headings are seemingly maintained by direct detection of wind-related turbulent cues. Despite being far more abundant and speciose, the day-flying windborne migrant fauna has been much less studied by radar; thus the frequency of wind-related common orientation patterns and the sensory mechanisms involved in their formation remain to be established. Here we analyze a large dataset of >600,000 radar-detected ‘medium-sized’ windborne insect migrants (body mass from 10 to 70 mg, flying hundreds of meters above southern UK, during the afternoon, in the period around sunset, and in the middle of the night. We found that wind-related common orientation was almost ubiquitous during the day (present in 97% of all ‘migration events’ analyzed, and was also frequent at sunset (85% and at night (81%. Headings were systematically offset to the right of the flow at night-time (as predicted from the use of turbulence cues for flow assessment, but there was no directional bias in the offsets during the day or at sunset. Orientation ‘performance’ significantly increased with increasing flight altitude throughout the day and night. We conclude by discussing sensory mechanisms which most likely play a role in the selection and maintenance of wind-related flight headings.

  14. Study of Raman Spectroscopy on Phase Relations of CaCO3 at High Temperature and High Pressure

    Science.gov (United States)

    Li, M.; Zheng, H.; Duan, T.

    2006-05-01

    Laser Raman Spectroscopy was used to study phase relations between calcite I, calcite II and aragonite at high pressure and high temperature. The experiment was performed in an externally heated Basselt type diamond anvil cell (DAC). Natural calcite (calcite I) was used as starting mineral. The sample and a small chip of quartz were loaded in a cavity (300 μm in diameter and 250 μm in depth) in a rhenium gasket. The Na2CO3 aqueous solution of 1mol/L was also loaded as a pressure medium to yield hydrostatic pressure. The whole assembly was pressurized first and then heated stepwise to 400°C. Pressure and temperature in the chamber were determined by the shift of Raman band at 464 cm-1 of quartz and by NiCr-NiSi thermocouple, respectively. The Raman spectra were measured by a Renishaw 1000 spetrometer with 50 mW of 514.5nm argon-ion laser as the excitation light source. The slit width was 50 μm and the corresponding resolution was ±1 cm-1. From the experiments, we observed the phase transitions between calcite I and calcite II, calcite I and aragonite, calcite II and aragonite, respectively. Our data showed a negative slope for the boundary between calcite I and calcite II, which was similar to Bridgman's result, although Hess et al. gave a positive slope. The boundary with a negative slope for calcite II and aragonite was also defined, which had never been done before. And all these data can yield a more complete phase diagram of CaCO3 than the studies of Hess et al. and Suito et al.Reference:Bridgeman P. W.(1939) Journal: American Journal of Science, Vol. 237, p. 7-18Bassett W. A. et al. (1993) Journal: Review of Scientific Instruments, Vol. 64, p. 2340-2345Suito K. et al. (2001) Journal: American Mineralogist, Vol. 86, p. 997- 1002Hess N. J. et al. (1991) In A. K. Singh, Ed., Recent Trends in High Pressure Research; Proc. X IIIth AIRAPT International Conference on High Pressure Science and Technology, p. 236-241. Oxford & IBH Publishing Co. Pvt, Ltd., New

  15. Impact of Sport-related Games on High School Students’ Communication Skills

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    Ozturk Ozden Tepekoylu

    2015-09-01

    Full Text Available In Recent studies underline the fact that adolescents are, at many times, likely to experience serious communication problems with their families and close environments. So, the aim of this study is to determine positive impact of sport-related games, which are performed as extracurricular activities, on high school students’ communication skills. In the study, pre, & post-tests was utilized with the control group’s experimental patterns. Two participant groups were made up of totally 30 high school students, 15 of whom would be in the experimental group and the rest of whom were in the control group. The former group was given sport- related 20 applications for 10 weeks during which the latter group would not deal with any extracurricular activities. Meanwhile, before and after the applications, data was collected by means of “The Communication Skills Scale” which was developed by Korkut (1996 and then analysed through “two-way ANCOVA” test techniques. Results clarify that the considerable gap in scores of the students’ pre, & post-tests perception concerning their communication skills are clearly attributed to sport-related games and it was also established that scores of the students in the experimental group were meaningfully higher than ones in the control group. However, perception of communication skills in the both groups was not significantly different by sex of the students. Moreover, the common effect of sex and participation on sport- related games was not found statistically meaningful in terms of communication skills. Consequently, it could be said that sport-related games impact positively communication skills.

  16. Work Sectors with High Risk for Work-Related Musculoskeletal Disorders in Korean Men and Women

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    Jungsun Park

    2018-03-01

    Full Text Available Background: To identify work sectors with high risk for work-related musculoskeletal disorders (MSDs in Korean men and women. Methods: We analyzed nationwide data to identify ergonomic risk factors in Korean employees. In particular, we analyzed data on exposure to five ergonomic risk factors (painful/tiring postures, lifting/moving heavy materials, standing/walking, repetitive hand/arm movements, and hand/arm vibration according to employment sector, sex, and age, using the 2014 Fourth Korean Working Conditions Survey. We also used workers' compensation data on work-related MSDs in 2010, which is available by sex. Results: The different work sectors had different gender distributions. “Manufacturing” (27.7% and “construction” (11.3% were dominated by males, whereas “human health and social work activities” (12.4%, “hotel and restaurants” (11.7%, and “education” (10.4% were dominated by females. However, “wholesale and retail trade” and “public administration and defense” employed large numbers of males and females. Furthermore, the work sectors with a greater proportion of work-related MSDs and with multiple ergonomic risk factors were different for men and women. For men, “construction” and “manufacturing” had the highest risk for work-related MSDs; for women, “hotel and restaurants” had the highest risk for work-related MSDs. Conclusion: Ergonomic interventions for workers should consider gender and should focus on work sectors with high risk for MSDs, with multiple ergonomic risk factors, and with the largest number of workers. Keywords: ergonomic, risk factor, Korean workers, musculoskeletal disorder

  17. The identification of high potential archers based on relative psychological coping skills variables: A Support Vector Machine approach

    Science.gov (United States)

    Taha, Zahari; Muazu Musa, Rabiu; Majeed, A. P. P. Abdul; Razali Abdullah, Mohamad; Aizzat Zakaria, Muhammad; Muaz Alim, Muhammad; Arif Mat Jizat, Jessnor; Fauzi Ibrahim, Mohamad

    2018-03-01

    Support Vector Machine (SVM) has been revealed to be a powerful learning algorithm for classification and prediction. However, the use of SVM for prediction and classification in sport is at its inception. The present study classified and predicted high and low potential archers from a collection of psychological coping skills variables trained on different SVMs. 50 youth archers with the average age and standard deviation of (17.0 ±.056) gathered from various archery programmes completed a one end shooting score test. Psychological coping skills inventory which evaluates the archers level of related coping skills were filled out by the archers prior to their shooting tests. k-means cluster analysis was applied to cluster the archers based on their scores on variables assessed. SVM models, i.e. linear and fine radial basis function (RBF) kernel functions, were trained on the psychological variables. The k-means clustered the archers into high psychologically prepared archers (HPPA) and low psychologically prepared archers (LPPA), respectively. It was demonstrated that the linear SVM exhibited good accuracy and precision throughout the exercise with an accuracy of 92% and considerably fewer error rate for the prediction of the HPPA and the LPPA as compared to the fine RBF SVM. The findings of this investigation can be valuable to coaches and sports managers to recognise high potential athletes from the selected psychological coping skills variables examined which would consequently save time and energy during talent identification and development programme.

  18. The topographic relations of the high jugular fossa to the inner ear

    International Nuclear Information System (INIS)

    Wadin, K.; Wilbrand, H.

    1986-01-01

    The radioanatomy of high jugular fossae and their topographic relations to the inner ear structures were investigated in 245 unselected temporal bones. One hundred and fifty specimens were submitted to multidirectional and 10 to computed tomography. After careful chemical and fermentative maceration plastic casts were made, using polyester resin and silicone rubber. With the use of vacuum, even minute structures became filled with the casting material. The specimens offered a three-dimensional view of the jugular fossae and surrounding structures. Fifty-eight (24%) of the total 245 specimens had high jugular fossae at a level above the lower border of the round window. Five casts showed a dehiscence of the peripheral portion of the vestibular aqueduct caused by the high jugular fossa. In 2 casts the proximal portion of the cochlear aqueduct was affected. In some casts the posterior semicircular canal, the facial canal, the stapedial muscle and the round window lay so close to the fossa that a dehiscence could not be excluded. In a clinical material of 102 high fossae the radiographic findings were in accordance with the experimental results. High jugular fossae were predominantly found in pyramids with low-grade mastoid bone pneumatization and sparse or no perilabyrinthine air cells. (orig.)

  19. Winter cloudiness variability over Northern Eurasia related to the Siberian High during 1966–2010

    International Nuclear Information System (INIS)

    Chernokulsky, Alexander; Mokhov, Igor I; Nikitina, Natalia

    2013-01-01

    This letter presents an assessment of winter cloudiness variability over Northern Eurasia regions related to the Siberian High intensity (SHI) variations during 1966–2010. An analysis of cloud fraction and the occurrence of different cloud types was carried out based on visual observations from almost 500 Russian meteorological stations. The moonlight criterion was implemented to reduce the uncertainty of night observations. The SHI was defined based on sea-level pressure fields from different reanalyses. We found a statistically significant negative correlation of cloud cover with the SHI over central and southern Siberia and the southern Urals with regression coefficients around 3% hPa −1 for total cloud fraction (TCF) for particular stations near the Siberian High center. Cross-wavelet analysis of TCF and SHI revealed a long-term relationship between cloudiness and the Siberian High. Generally, the Siberian High intensification by 1 hPa leads to a replacement of one overcast day with one day without clouds, which is associated mainly with a decrease in precipitating and stratiform clouds. These changes point to a positive feedback between cloudiness and the Siberian High. (letter)

  20. Rapid L2 Word Learning through High Constraint Sentence Context: An Event-Related Potential Study

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    Baoguo Chen

    2017-12-01

    Full Text Available Previous studies have found quantity of exposure, i.e., frequency of exposure (Horst et al., 1998; Webb, 2008; Pellicer-Sánchez and Schmitt, 2010, is important for second language (L2 contextual word learning. Besides this factor, context constraint and L2 proficiency level have also been found to affect contextual word learning (Pulido, 2003; Tekmen and Daloglu, 2006; Elgort et al., 2015; Ma et al., 2015. In the present study, we adopted the event-related potential (ERP technique and chose high constraint sentences as reading materials to further explore the effects of quantity of exposure and proficiency on L2 contextual word learning. Participants were Chinese learners of English with different English proficiency levels. For each novel word, there were four high constraint sentences with the critical word at the end of the sentence. Learners read sentences and made semantic relatedness judgment afterwards, with ERPs recorded. Results showed that in the high constraint condition where each pseudoword was embedded in four sentences with consistent meaning, N400 amplitude upon this pseudoword decreased significantly as learners read the first two sentences. High proficiency learners responded faster in the semantic relatedness judgment task. These results suggest that in high quality sentence contexts, L2 learners could rapidly acquire word meaning without multiple exposures, and L2 proficiency facilitated this learning process.