Pattern of Demand For Money

Directory of Open Access Journals (Sweden)

Ahmad Berlian

2017-12-01

Full Text Available In the activity of the modern economy, the availability of money as a means of transaction is very important, because with the money as a means to pay consumers can easily to get the basic material needs are required, the manufacturer can provide the raw materials of labor for production, and distributors can obtain a variety of merchandise to be delivered at the end consumer. The pattern of use of money is influenced by the attitude of the public in the transaction. Researchers assume, that there are differences among communities, either by group differences in income, educational differences, ethnic differences, differences in profession, and perhaps even religious differences embraced. So as to provide information to the monetary authorities, to enrich the theory of demand for money based economic agents in Indonesia, and for the application of the theory of demand for money, the researchers felt the need to study patterns of use of money. Qualitative research, in addition to knowing whether the variables that affect the demand for money as the above theory is still relevant for economic actors in Indonesia at this time, or even are new variables, as well as the motive of money demand. Keywords: Demand for money, Keynes Theory, qualitative method

FOOD DEMAND PATTERNS IN GHANAIAN URBAN HOUSEHOLDS

Directory of Open Access Journals (Sweden)

Bernard SAKYIAMAH

2018-03-01

Full Text Available This paper analysed food consumption patterns in Ghanaian urban households by comparing food commodity budget shares and estimating price and expenditure elasticities for eleven food commodity groups across different income groups. The Linear Approximation Almost Ideal Demand System (LA/AIDS was applied to the data. Demand for most of the food commodity groups was found to be elastic. The study concluded that generally, across income groups, food commodities respond negatively to changes in food prices and that cereals/bread, roots/tubers, vegetables, meat and fish will remain an important component of urban household food expenditure. Generally, household demographic characteristics such as age, gender and household size had significant effects on urban food demand patterns.

Communications technologies for demand side management, DSM, and European utility communications architecture, EurUCA

Energy Technology Data Exchange (ETDEWEB)

Uuspaeae, P. [VTT Energy, Espoo (Finland)

1996-12-31

The scope of this research is data communications for electric utilities. Demand Side Management (DSM) calls for communication between the Electric Utility and the Customer. The communication capacity needed will depend on the functions that are chosen for DSM, and on the number of customers. Some functions may be handled with one-way communications, some functions require two-way communication. Utility Communication Architecture looks for an overall view of the communications needs and communication systems in an electric utility. The objective is to define and specify suitable and compatible communications procedures within the Utility and also to outside parties. (27 refs.)

Communications technologies for demand side management, DSM, and European utility communications architecture, EurUCA

Energy Technology Data Exchange (ETDEWEB)

Uuspaeae, P [VTT Energy, Espoo (Finland)

1997-12-31

The scope of this research is data communications for electric utilities. Demand Side Management (DSM) calls for communication between the Electric Utility and the Customer. The communication capacity needed will depend on the functions that are chosen for DSM, and on the number of customers. Some functions may be handled with one-way communications, some functions require two-way communication. Utility Communication Architecture looks for an overall view of the communications needs and communication systems in an electric utility. The objective is to define and specify suitable and compatible communications procedures within the Utility and also to outside parties. (27 refs.)

The benzodiazepine withdrawal syndrome and its management.

OpenAIRE

Onyett, S R

1989-01-01

The literature on benzodiazepine dependence and withdrawal is reviewed with an emphasis on social and psychological considerations. The problems of when to prescribe, identifying withdrawal symptoms, effective communication with the patient, the structure of withdrawal programmes, and the use of drugs, psychological approaches and other services are discussed.

47 CFR 1.8 - Withdrawal of papers.

Science.gov (United States)

2010-10-01

... 47 Telecommunication 1 2010-10-01 2010-10-01 false Withdrawal of papers. 1.8 Section 1.8 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL PRACTICE AND PROCEDURE General Rules of Practice and Procedure General § 1.8 Withdrawal of papers. The granting of a request to dismiss or withdraw an...

Energy demand patterns

Energy Technology Data Exchange (ETDEWEB)

Hoffmann, L; Schipper, L; Meyers, S; Sathaye, J; Hara, Y

1984-05-01

This report brings together three papers on energy demand presented at the Energy Research Priorities Seminar held in Ottawa on 8-10 August 1983. The first paper suggests a framework in which energy demand studies may be organized if they are to be useful in policy-making. Disaggregation and the analysis of the chain of energy transformations are possible paths toward more stable and reliable parameters. The second paper points to another factor that leads to instability in sectoral parameters, namely a changeover from one technology to another; insofar as technologies producing a product (or service) vary in their energy intensity, a technological shift will also change the energy intensity of the product. Rapid technological change is characteristic of some sectors in developing countries, and may well account for the high aggregate GDP-elasticities of energy consumption observed. The third paper begins with estimates of these elasticities, which were greater than one for all the member countries of the Asian Development Bank in 1961-78. The high elasticities, together with extreme oil dependence, made them vulnerable to the drastic rise in the oil price after 1973. The author distinguishes three diverging patterns of national experience. The oil-surplus countries naturally gained from the rise in the oil price. Among oil-deficit countries, the newly industrialized countries expanded their exports so rapidly that the oil crisis no longer worried them. For the rest, balance of payments adjustments became a prime concern of policy. Whether they dealt with the oil bill by borrowing, by import substitution, or by demand restraint, the impact of energy on their growth was unmistakable. The paper also shows why energy-demand studies, and energy studies in general, deserve to be taken seriously. 16 refs., 4 figs., 18 tabs.

CALCULATING WATER CONSUMPTION AND WITHDRAWAL FROM POWER PLANTS GLOBALLYUsing machine learning, remote sensing and power plant data from the Power Watch platform

Science.gov (United States)

Kressig, A.

2017-12-01

BACKGROUND The Greenhouse Gas Protocol (GHGP), Scope 2 Guidance standardizes how companies measure greenhouse gas emissions from purchased or independently generated electricity (called "scope 2 emissions"). Additionally, the interlinkages between industrial or commercial (nonresidential) energy requirements and water demands have been studied extensively, mostly at the national or provincial scale, focused on industries involved in power generation. However there is little guidance available for companies to systematically and effectively quantify water withdrawals and consumption (herein referred to as "water demand") associated with purchased or acquired electricity(what we call "Scope 2 Water"). This lack of guidance on measuring a company's water demand from electricity use is due to a lack of data on average consumption and withdrawal rates of water associated with purchased electricity. OBJECTIVE There is growing demand from companies in the food, beverage, manufacturing, information communication and technology, and other sectors for a methodology to quantify Scope 2 water demands. By understanding Scope 2 water demands, companies could evaluate their exposure to water-related risks associated with purchased or acquired electricity, and quantify the water benefits of changing to less water-intensive sources of electricity and energy generation such as wind and solar. However, there has never been a way of quantifying Scope 2 Water consumption and withdrawals for a company across its international supply chain. Even with interest in understanding exposure to water related risk and measuring water use reductions, there has been no quantitative way of measuring this information. But WRI's Power Watch provides the necessary data to allow for the Scope 2 Water accounting, because it will provide water withdrawal and consumption rates associated with purchased electricity at the power plant level. By calculating the average consumption and withdrawal rates per

The Effectiveness of Collaborative Couple Therapy on Communication Patterns and Intimacy of Couples Referring to Counseling Centers of Behbahan, Iran

Directory of Open Access Journals (Sweden)

M Sodani

2017-07-01

Full Text Available Abstract Background and Aim: Intimacy is a key characteristic of marital relationships and is one of the most prominent characteristics of a successful marriage. Communication patterns can also determine marital satisfaction. The aim of this study was to determine the effectiveness of coupled collaborative therapy on communication patterns and intimacy of couples referring to Behbahan counseling centers. Methods: In this research, a single-trial experimental design, which was also called a single-trial trial, was used as a clinical trial. This design has different types. In the present study, several asynchronous base lines were used. Contrary to large-scale group comparison schemes, this design focuses on individual levels, not on average differences in pre-test and post-test. Another point of this plan is that fewer subjects are needed and couples completed the intimate questionnaire and communication patterns on the baseline, treatment and follow-up. Purposeful sampling was voluntary. The population of the study consisted of all disturbed couples referring to Behbahan psychological clinics. From these couples, 3 couples were selected based on entry and exit criteria. For analyzing the data, visual analysis (chart drawing, clinical significance (the changeover index and normative comparison, as well as the percentage of recovery, have been used. Results: The results indicated that couples experience improvement in intimacy (30.95% and interactive constructive communication model (47.05%, and in the communication model, the expected return (29.55% and communication pattern Interactive avoidance (33.64% showed a decrease. Likewise, data analysis using normative comparison showed that the couples after the treatment did not differ from the couples to the norm. Conclusion: Participatory couples’s therapy may increase the intimacy and constructive communication patterns and decrease the communication patterns of waiting and withdrawal

Patterns of interhemispheric correlation during human communication.

Science.gov (United States)

Grinberg-Zylberbaum, J; Ramos, J

1987-09-01

Correlation patterns between the electroencephalographic activity of both hemispheres in adult subjects were obtained. The morphology of these patterns for one subject was compared with another subject's patterns during control situations without communication, and during sessions in which direct communication was stimulated. Neither verbalization nor visual or physical contact are necessary for direct communication to occur. The interhemispheric correlation patterns for each subject were observed to become similar during the communication sessions as compared to the control situations. These effects are not due to nonspecific factors such as habituation or fatigue. The results support the syntergic theory proposed by one of the authors (Grinberg-Zylberbaum).

Evaluation of the appropriate use of a CIWA-Ar alcohol withdrawal protocol in the general hospital setting.

Science.gov (United States)

Eloma, Amanda S; Tucciarone, Jason M; Hayes, Edmund M; Bronson, Brian D

2018-01-01

The Clinical Institute Withdrawal Assessment-Alcohol, Revised (CIWA-Ar) is an assessment tool used to quantify alcohol withdrawal syndrome (AWS) severity and inform benzodiazepine treatment for alcohol withdrawal. To evaluate the prescribing patterns and appropriate use of the CIWA-Ar protocol in a general hospital setting, as determined by the presence or absence of documented AWS risk factors, patients' ability to communicate, and provider awareness of the CIWA-Ar order. This retrospective chart review included 118 encounters of hospitalized patients placed on a CIWA-Ar protocol during one year. The following data were collected for each encounter: patient demographics, admitting diagnosis, ability to communicate, and admission blood alcohol level; and medical specialty of the clinician ordering CIWA-Ar, documentation of the presence or absence of established AWS risk factors, specific parameters of the protocol ordered, service admitted to, provider documentation of awareness of the active protocol within 48 h of initial order, total benzodiazepine dose equivalents administered and associated adverse events. 57% of patients who started on a CIWA-Ar protocol had either zero or one documented risk factor for AWS (19% and 38% respectively). 20% had no documentation of recent alcohol use. 14% were unable to communicate. 19% of medical records lacked documentation of provider awareness of the ordered protocol. Benzodiazepine associated adverse events were documented in 15% of encounters. The judicious use of CIWA-Ar protocols in general hospitals requires mechanisms to ensure assessment of validated alcohol withdrawal risk factors, exclusion of patients who cannot communicate, and continuity of care during transitions.

Withdrawal: Expanding a Key Addiction Construct.

Science.gov (United States)

Piper, Megan E

2015-12-01

Withdrawal is an essential component of classical addiction theory; it is a vital manifestation of dependence and motivates relapse. However, the traditional conceptualization of withdrawal as a cohesive collection of symptoms that emerge during drug deprivation and decline with either the passage of time or reinstatement of drug use, may be inadequate to explain scientific findings or fit with modern theories of addiction. This article expands the current understanding of tobacco withdrawal by examining: (1) withdrawal variability; (2) underlying causes of withdrawal variability, including biological and person factors, environmental influences, and the influence of highly routinized behavioral patterns; (3) new withdrawal symptoms that allow for enhanced characterization of the withdrawal experience; and (4) withdrawal-related cognitive processes. These topics provide guidance regarding the optimal assessment of withdrawal and illustrate the potential impact modern withdrawal conceptualization and assessment could have on identifying treatment targets. © The Author 2015. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

INTERCULTURAL COMMUNICATION PATTERNS AND LANGUAGE USE IN COMPUTER MEDIATED-COMMUNICATION

OpenAIRE

Adriana Teodorescu

2012-01-01

This paper aims at analyzing the degree to which intercultural communication patterns are embedded in computer-mediated communication. Drawing on Hall's and Hofstede's intercultural communication dimensions, this study evaluates empirically high-versus-low context cultural orientations as reflected in the electronic medium, namely the blog, in three different cultures. Cultural variation is also analyzed in linguistic features and communication style in a synchronous mode of communication, by...

Integration of Individual Processes and Information Demand Patterns: A Conceptual Analysis

Directory of Open Access Journals (Sweden)

Michael Leyer

2017-12-01

Full Text Available Individuals need a variety of information when performing their personal processes. However, companies typically know little about the underlying individual demand patterns in these processes. Conceptualizing information demand patterns of individuals is expected to allow for using these as foundation to extend the traditional internal information logistic perspective of companies. Digital options could then be used to align individual and organizational information leading not only to new product and service offers, but also to new work structures in organizations. Thus, we extend prior literature regarding business process management and information logistics by highlighting how information demand patterns (IDP have to be adapted to individual processes. Our exploratory approach is to demonstrate conceptually the conditions and implications of individual IDPs.

Patterns of communication in high-fidelity simulation.

Science.gov (United States)

Anderson, Judy K; Nelson, Kimberly

2015-01-01

High-fidelity simulation is commonplace in nursing education. However, critical thinking, decision making, and psychomotor skills scenarios are emphasized. Scenarios involving communication occur in interprofessional or intraprofessional settings. The importance of effective nurse-patient communication is reflected in statements from the American Nurses Association and Quality and Safety Education for Nurses, and in the graduate outcomes of most nursing programs. This qualitative study examined the patterns of communication observed in video recordings of a medical-surgical scenario with 71 senior students in a baccalaureate program. Thematic analysis revealed patterns of (a) focusing on tasks, (b) communicating-in-action, and (c) being therapeutic. Additional categories under the patterns included missing opportunities, viewing the "small picture," relying on informing, speaking in "medical tongues," offering choices…okay?, feeling uncomfortable, and using therapeutic techniques. The findings suggest the importance of using high-fidelity simulation to develop expertise in communication. In addition, the findings reinforce the recommendation to prioritize communication aspects of scenarios and debriefing for all simulations. Copyright 2015, SLACK Incorporated.

Improving operating room coordination: communication pattern assessment.

Science.gov (United States)

Moss, Jacqueline; Xiao, Yan

2004-02-01

To capture communication patterns in operating room (OR) management to characterize the information needs of OR coordination. Technological applications can be used to change system processes to improve communication and information access, thereby decreasing errors and adverse events. The successful design of such applications relies on an understanding of communication patterns among healthcare professionals. Charge nurse communication was observed and documented at four OR suites at three tertiary hospitals. The data collection tool allowed rapid coding of communication patterns in terms of duration, mode, target person, and the purpose of each communication episode. Most (69.24%) of the 2074 communication episodes observed occurred face to face. Coordinating equipment was the most frequently occurring purpose of communication (38.7%) in all suites. The frequency of other purposes in decreasing order were coordinating patient preparedness (25.7%), staffing (18.8%), room assignment (10.7%), and scheduling and rescheduling surgery (6.2%). The results of this study suggest that automating aspects of preparing patients for surgery and surgical equipment management has the potential to reduce information exchange, decreasing interruptions to clinicians and diminishing the possibility of adverse events in the clinical setting.

Pattern of demand for children in Pakistan.

Science.gov (United States)

Ahmed, T

1992-01-01

The study aim was to determine the pattern of demand for children and to suggest ways to introduce the idea of a small-family norm and reduce the unmet need for contraception in Pakistan. The concept of demand for children included the wantedness of the last birth and the timing of the next birth and changed with stage in reproductive life cycle. Data were obtained from the Pakistan Contraception Prevalence Survey of 1984/85. Pakistan's strong patriarchal system emphasized rapid achievement of first pregnancy in order to assure the perpetuation of the lineage. Female status, even with advanced education, emphasized fecundity and producing a male heir. The birthing pattern among rural and urban lower-class women is to bear 3-4 children early in marriage. Evidence from prior surveys showed that educated women plan for a delay in second birth. Of the 6655 ever pregnant and nonsterilized women, about 48% of currently married women desired discontinuation of childbearing. 18% desired a delay of childbearing by 2 years and 10% desired no more children after a last undesired pregnancy. Unmet need was estimated at 17% of all women in the sample. Women desiring no more children were primarily older with 6-8 prior births. Indirect fertility estimates were generated by using Arriaga's techniques for stages of family formation. The resulting estimates showed that higher-parity women desiring no more children still had 2 more children, which was evidence of unmet need. Those desiring more children had higher fertility than those not desiring more children. These women also showed different patterns in their total demand for children, ideal family size, currently living children, and desire for their next birth. Ideal size tended to rise over the length of a marriage, which may mean that women with growing families may justify unwanted fertility. Duration of marriage was viewed as a reasonable indicator of need for fertility control and the concomitant need for outreach

INTERCULTURAL COMMUNICATION PATTERNS AND LANGUAGE USE IN COMPUTER MEDIATED-COMMUNICATION

Directory of Open Access Journals (Sweden)

Adriana Teodorescu

2012-11-01

Full Text Available This paper aims at analyzing the degree to which intercultural communication patterns are embedded in computer-mediated communication. Drawing on Hall’s and Hofstede’s intercultural communication dimensions, this study evaluates empirically high-versus-low context cultural orientations as reflected in the electronic medium, namely the blog, in three different cultures. Cultural variation is also analyzed in linguistic features and communication style in a synchronous mode of communication, by investigating data from several popular blogs from Japan, Germany and Italy.

Demand response driven load pattern elasticity analysis for smart households

NARCIS (Netherlands)

Paterakis, N.G.; Catalao, J.P.S.; Tascikaraoglu, A.; Bakirtzis, A.G.; Erdinc, O.

2015-01-01

The recent interest in smart grid vision enables several smart applications in different parts of the power grid structure, where specific importance should be given to the demand side. As a result, changes in load patterns due to demand response (DR) activities at end-user premises, such as smart

Holidays in lights: Tracking cultural patterns in demand for energy services

Science.gov (United States)

Román, Miguel O.; Stokes, Eleanor C.

2015-06-01

Successful climate change mitigation will involve not only technological innovation, but also innovation in how we understand the societal and individual behaviors that shape the demand for energy services. Traditionally, individual energy behaviors have been described as a function of utility optimization and behavioral economics, with price restructuring as the dominant policy lever. Previous research at the macro-level has identified economic activity, power generation and technology, and economic role as significant factors that shape energy use. However, most demand models lack basic contextual information on how dominant social phenomenon, the changing demographics of cities, and the sociocultural setting within which people operate, affect energy decisions and use patterns. Here we use high-quality Suomi-NPP VIIRS nighttime environmental products to: (1) observe aggregate human behavior through variations in energy service demand patterns during the Christmas and New Year's season and the Holy Month of Ramadan and (2) demonstrate that patterns in energy behaviors closely track sociocultural boundaries at the country, city, and district level. These findings indicate that energy decision making and demand is a sociocultural process as well as an economic process, often involving a combination of individual price-based incentives and societal-level factors. While nighttime satellite imagery has been used to map regional energy infrastructure distribution, tracking daily dynamic lighting demand at three major scales of urbanization is novel. This methodology can enrich research on the relative importance of drivers of energy demand and conservation behaviors at fine scales. Our initial results demonstrate the importance of seating energy demand frameworks in a social context.

Holiday in Lights: Tracking Cultural Patterns in Demand for Energy Services

Science.gov (United States)

Roman, Miguel O.; Stokes, Eleanor C.

2015-01-01

Successful climate change mitigation will involve not only technological innovation, but also innovation in how we understand the societal and individual behaviors that shape the demand for energy services. Traditionally, individual energy behaviors have been described as a function of utility optimization and behavioral economics, with price restructuring as the dominant policy lever. Previous research at the macro-level has identified economic activity, power generation and technology, and economic role as significant factors that shape energy use. However, most demand models lack basic contextual information on how dominant social phenomenon, the changing demographics of cities, and the sociocultural setting within which people operate, affect energy decisions and use patterns. Here we use high-quality Suomi-NPP VIIRS nighttime environmental products to: (1) observe aggregate human behavior through variations in energy service demand patterns during the Christmas and New Year's season and the Holy Month of Ramadan and (2) demonstrate that patterns in energy behaviors closely track sociocultural boundaries at the country, city, and district level. These findings indicate that energy decision making and demand is a sociocultural process as well as an economic process, often involving a combination of individual price-based incentives and societal-level factors. While nighttime satellite imagery has been used to map regional energy infrastructure distribution, tracking daily dynamic lighting demand at three major scales of urbanization is novel. This methodology can enrich research on the relative importance of drivers of energy demand and conservation behaviors at fine scales. Our initial results demonstrate the importance of seating energy demand frameworks in a social context.

Control rod pattern exchange in a BWR/6 utilizing gang mode withdrawal

International Nuclear Information System (INIS)

Auvil, A.B. Jr.; Aldemir, T.; Hajek, B.K.

1986-01-01

The use of checkerboard pattern of alternating inserted and fully withdrawn control rods and the uneven void distribution in boiling water reactor (BWR) cores can cause large burnup gradients even after a short time of operation. To compensate for these effects, power has to be reshaped periodically (typically every two full-power months) by individually manipulating the control rods. During this manipulation process (called the control rod pattern exchange), the core power is reduced to 60% of nominal power by means of flow reduction to limit power swings to tolerable levels and to ensure that fuel thermal limits are not exceeded. A control rod pattern exchange by individual rod manipulation typically takes 4 to 8 h and represents a large cost burden to the utility in terms of reduced system output. The latest generation of BWRs, the BWR/6, possesses the capability to simultaneously move up to four symmetrically located control rods. The rods corresponding to a given gang may have rotational symmetry, mirror symmetry, or a combination of the two. This paper presents a pattern exchange procedure that exploits the capability of gang mode rod withdrawal to reduce the pattern exchange execution time and radial power distribution asymmetry associated with individual rod manipulation. The working model used in the study is the Perry Nuclear Power Plant Unit 1, located in Perry, Ohio, and owned by the Cleveland Electric Illuminating Company

[Interactive patterns detection in family communication with adolescents].

Science.gov (United States)

Gimeno Collado, Adelina; Anguera Argilaga, M Teresa; Berzosa Sanz, Amparo; Ramírez Ramírez, Luis

2006-11-01

Interactive patterns detection in family communication with adolescents. Nondistant communication is a relevant indicator for family functionality valuation. The goal of this study is to analyze this communication in order to identify specific kinds of leadership, interaction patterns and the relation between verbal and nonverbal elements in communication. The observational design exposed is an idiographic one, punctual and multidimensional, which uses field format as observation instrument. Participants were seven standardized families made up of both ancestors and an adolescent son or daughter. According to the family models analyzed, results show a predominantly democratic communication style in adults with recurrent support expressions. The sequential analysis incorporates only categories from the emitter point of view, and detects relevant sequences which show symmetric interaction between all three family members. Verbal and nonverbal channels provide complementary information. Depending on adolescents' gender different patterns in behaviour can be identified as well.

Electricity demand forecasting using regression, scenarios and pattern analysis

CSIR Research Space (South Africa)

Khuluse, S

2009-02-01

Full Text Available The objective of the study is to forecast national electricity demand patterns for a period of twenty years: total annual consumption and understanding seasonal effects. No constraint on the supply of electricity was assumed...

Demand management through centralized control system using power line communication for existing buildings

International Nuclear Information System (INIS)

Al-Mulla, A.; ElSherbini, A.

2014-01-01

Highlights: • A pilot system was developed for demand management of equipment in buildings. • The networking was based on LonWorks platform and power line communication. • Demand strategies led to load reductions up to 74% and energy savings up to 25%. • The peak load reduction is expected to reach 3.44 GW by the year 2030. - Abstract: Managing peak demand efficiently is vital for maintaining uninterrupted supply of electrical power by utility providers. In this work, a pilot system was developed for managing and controlling the demand of major power consuming equipment in buildings from a central server, while relying mostly on existing infrastructure and maintaining consumer comfort. The system was successfully demonstrated on a selected group of buildings using the LonWorks networking platform. At the building level, the system utilized power line and twisted pair communication to control the thermostats of air-conditioning (A/C) units. The higher level communication was executed through extensible markup language (XML) and simple object access protocol (SOAP). The system provided control capabilities based on A/C unit priority, thermostat temperature, building type and geographic location. The development and execution of demand management strategies for selected buildings led to peak load reductions up to 74%, in addition to energy savings up to 25%. Implementing such a system at a national level in Kuwait is estimated to reduce peak demand by 3.44 GW, amounting to capital savings of $4.13 billion. The use of existing infrastructure reduced the cost and installation time of the system. Based on the successful testing of this pilot system, a larger-scale system is being developed

Social transfer of alcohol withdrawal-induced hyperalgesia in female prairie voles.

Science.gov (United States)

Walcott, Andre T; Smith, Monique L; Loftis, Jennifer M; Ryabinin, Andrey E

2018-03-27

The expression of pain serves as a way for animals to communicate potential dangers to nearby conspecifics. Recent research demonstrated that mice undergoing alcohol or morphine withdrawal, or inflammation, could socially communicate their hyperalgesia to nearby mice. However, it is unknown whether such social transfer of hyperalgesia can be observed in other species of rodents. Therefore, the present study investigated if the social transfer of hyperalgesia occurs in the highly social prairie vole (Microtus ochrogaster). We observe that adult female prairie voles undergoing withdrawal from voluntary two-bottle choice alcohol drinking display an increase in nociception. This alcohol withdrawal-induced hypersensitiity is socially transferred to female siblings within the same cage and female strangers housed in separate cages within the same room. These experiments reveal that the social transfer of pain phenomenon is not specific to inbred mouse strains and that prairie voles display alcohol withdrawal and social transfer-induced hyperalgesia.

Development of a demand assignment/TDMA system for international business satellite communications

Science.gov (United States)

Nohara, Mitsuo; Takeuchi, Yoshio; Takahata, Fumio; Hirata, Yasuo; Yamazaki, Yoshiharu

An experimental IBS (international business satellite) communications system based on a demand assignment and TDMA (time-division multiple-access) operation has been developed. The system utilizes a limited satellite resource efficiently and provides various kinds of ISDN services totally. A discussion is presented of the IBS network configurations suitable to international communications and describes the developed communications system from the viewpoint of the hardware and software implementation. The performance in terms of the transmission quality and call processing is also demonstrated.

The effects of withdrawals and drought on groundwater availability in the Northern Guam Lens Aquifer, Guam

Science.gov (United States)

Gingerich, Stephen B.

2013-01-01

Owing to population growth, freshwater demand on Guam has increased in the past and will likely increase in the future. During the early 1970s to 2010, groundwater withdrawals from the limestone Northern Guam Lens Aquifer, the main source of freshwater on the island, tripled from about 15 to 45 million gallons per day. Because of proposed military relocation to Guam and expected population growth, freshwater demand on Guam is projected to increase further. The expected increased demand for groundwater has led to concern over the long-term sustainability of withdrawals from existing and proposed wells. A three-dimensional numerical groundwater flow and transport model was developed to simulate the effects of hypothetical withdrawal and recharge scenarios on water levels and on the transition zone between freshwater and saltwater. The model was constructed by using average recharge during 1961–2005 and withdrawals from 2010. Hydraulic properties used to construct the model were initially based on published estimates but ultimately were adjusted to obtain better agreement between simulated and measured water levels and salinity profiles in the modeled area. Two hypothetical groundwater withdrawal scenarios were simulated: no withdrawal to simulate predevelopment conditions and withdrawal at 2010 rates under a 5-year drought. Simulation results indicate that prior to pumping; the fresh-water lens was 10 to 50 feet thicker in the Yigo-Tumon basin and more than 50 feet thicker in the Hagåtña basin. Results also indicate that continuing the 2010 withdrawal distribution during a 5-year drought would result in decreased water levels, a thinner freshwater lens, and increased salinity of water pumped from wells. The available water with an acceptable salinity (chloride concentration less than 200 milligrams per liter) would decrease from about 34 million gallons per day to 11.5 million gallons per day after 5 years but recover to pre-drought levels 5 years after the

Adolescent-Parent Communication in a Digital World: Differences by Family Communication Patterns

Science.gov (United States)

Rudi, Jessie H.; Walkner, Amy; Dworkin, Jodi

2015-01-01

We examined how family communication patterns (FCPs) are associated with frequency of adolescent-parent communication in person, over the phone, via text message, and via email. Adolescents (N = 195) aged 13 to 18 completed an online survey assessing FCPs and frequency of communication methods used with parents. The results revealed that both…

Open Automated Demand Response Communications in Demand Response for Wholesale Ancillary Services

Energy Technology Data Exchange (ETDEWEB)

Kiliccote, Sila; Piette, Mary Ann; Ghatikar, Girish; Koch, Ed; Hennage, Dan; Hernandez, John; Chiu, Albert; Sezgen, Osman; Goodin, John

2009-11-06

The Pacific Gas and Electric Company (PG&E) is conducting a pilot program to investigate the technical feasibility of bidding certain demand response (DR) resources into the California Independent System Operator's (CAISO) day-ahead market for ancillary services nonspinning reserve. Three facilities, a retail store, a local government office building, and a bakery, are recruited into the pilot program. For each facility, hourly demand, and load curtailment potential are forecasted two days ahead and submitted to the CAISO the day before the operation as an available resource. These DR resources are optimized against all other generation resources in the CAISO ancillary service. Each facility is equipped with four-second real time telemetry equipment to ensure resource accountability and visibility to CAISO operators. When CAISO requests DR resources, PG&E's OpenADR (Open Automated DR) communications infrastructure is utilized to deliver DR signals to the facilities energy management and control systems (EMCS). The pre-programmed DR strategies are triggered without a human in the loop. This paper describes the automated system architecture and the flow of information to trigger and monitor the performance of the DR events. We outline the DR strategies at each of the participating facilities. At one site a real time electric measurement feedback loop is implemented to assure the delivery of CAISO dispatched demand reductions. Finally, we present results from each of the facilities and discuss findings.

Patterns of Physician-Patient Communication Associated with Patient Satisfaction.

Science.gov (United States)

Williams, M. Lee; Clampitt, Phillip G.

Using data drawn from ten initial physician/patient interviews, an original category system was employed to analyze patterns of physician/patient communication. Static analysis, interaction analysis, and Markov chain analysis were used to discover the underlying communication patterns associated with patient satisfaction. Results revealed that…

Communication Patterns, Contradictions, and Family Functions.

Science.gov (United States)

Yerby, Janet; Buerkel-Rothfuss, Nancy L.

Families are rule-governed systems of interdependent individuals whose interaction follows an intricate pattern of behavior. Communication patterns in a family reflect and emerge from contradictions in rules. A function may be defined as something that a system does and must do if it is not to break down. For instance identity and stability…

An up-link power control for demand assignment International Business Satellite Communications Network

Science.gov (United States)

Nohara, Mitsuo; Takeuchi, Yoshio; Takahata, Fumio

Up-link power control (UPC) is one of the essential technologies to provide efficient satellite communication systems operated at frequency bands above 10 GHz. A simple and cost-effective UPC scheme applicable to a demand assignment international business satellite communications system has been developed. This paper presents the UPC scheme, including the hardware implementation and its performance.

Non-electronic communication aids for people with complex communication needs.

Science.gov (United States)

Iacono, Teresa; Lyon, Katie; West, Denise

2011-10-01

Non-electronic communication aids provide one form of augmentative and alternative communication (AAC) for people with complex communication needs. The aim here was to explore non-electronic communication aids as one AAC option and research challenges. This aim was addressed by reviewing funding for the provision of AAC systems, data from an Australian pilot project providing non-electronic communication aids, an audit of aided AAC published studies (2000-2009), and discussion of the review literature. Combined, these sources indicate that although there is great demand for non-electronic communication aids, funding schemes, both in Australia and internationally, have focused on electronic communication aids. Such funding has usually failed to meet the total device costs and has not provided for adequate speech-language pathology support. Data from the pilot indicated the demand for non-electronic communication aids, and patterns suggest potential factors that govern the types selected. Despite the high demand for non-electronic aids, the research literature has tended to focus on electronic communication aids, including within intervention studies and addressing design features and long-term outcomes. Concerns about ensuring that AAC systems are chosen according to the assessed needs of individuals are discussed within the context of limitations in outcomes research and appropriate outcome measures.

Scholarly Communication and Authorship Patterns in Language ...

African Journals Online (AJOL)

2016-10-02

Oct 2, 2016 ... communication behaviour in languages using theses and ... device for communication and technical education, or as a vehicle and .... covering mainly English language titles from North America and Western Europe. .... concluded that theoretical linguistics reflects a publication pattern closer to the social.

Predictors of withdrawal: possible precursors of avoidant personality disorder.

Science.gov (United States)

Eggum, Natalie D; Eisenberg, Nancy; Spinrad, Tracy L; Valiente, Carlos; Edwards, Alison; Kupfer, Anne S; Reiser, Mark

2009-01-01

Relations of avoidant personality disorder (AvPD) with shyness and inhibition suggest that a precursor of AvPD is withdrawal. Using a sample of 4.5- to 7-year-olds studied four times, 2 years apart, four and three classes of children differing in trajectories of mother- and teacher-reported withdrawal, respectively, were identified. Mothers and teachers generally did not agree on children's trajectories but the pattern of findings in the two contexts did not differ markedly. The mother-identified high and declining withdrawal class, in comparison with less withdrawn classes, and the teacher-identified high and declining class compared with low withdrawal classes, were associated with relatively high levels of anger and low levels of attentional control and resiliency. The mother-identified moderate and increasing withdrawal class was distinguished from less problematic withdrawal classes by higher anger, lower resiliency, and sometimes, lower attentional control. The teacher-identified low and increasing withdrawal class was distinguished from less problematic withdrawal classes by lower resiliency and lower attentional control. Findings are discussed in terms of the developmental precursors to social withdrawal and avoidant behavior.

Dependence and withdrawal reactions to benzodiazepines and selective serotonin reuptake inhibitors. How did the health authorities react?

DEFF Research Database (Denmark)

Nielsen, Margrethe; Hansen, Ebba Holme; Gøtzsche, Peter C

2013-01-01

Our objective was to explore communications from drug agencies about benzodiazepine dependence and selective serotonin reuptake inhibitors (SSRIs) withdrawal reactions over time.......Our objective was to explore communications from drug agencies about benzodiazepine dependence and selective serotonin reuptake inhibitors (SSRIs) withdrawal reactions over time....

77 FR 40921 - Communication With Transport Vehicles

Science.gov (United States)

2012-07-11

... NUCLEAR REGULATORY COMMISSION [NRC-2012-0163] Communication With Transport Vehicles AGENCY... Commission (NRC or the Commission), is withdrawing Regulatory Guide 5.32, Revision 1, ``Communication with... withdrawing Regulatory Guide 5.32, revision 1, ``Communication with Transport Vehicles,'' published in May...

Patterns of family health history communication among older African American adults.

Science.gov (United States)

Hovick, Shelly R; Yamasaki, Jill S; Burton-Chase, Allison M; Peterson, Susan K

2015-01-01

This qualitative study examined patterns of communication regarding family health history among older African American adults. The authors conducted 5 focus groups and 6 semi-structured interviews with African Americans aged 60 years and older (N = 28). The authors identified 4 distinct patterns of family health history communication: noncommunication, open communication, selective communication (communication restricted to certain people or topics), and one-way communication (communication not reciprocated by younger family members). In general, participants favored open family health history communication, often resulting from desires to change patterns of noncommunication in previous generations regarding personal and family health history. Some participants indicated that they were selective about what and with whom they shared health information in order to protect their privacy and not worry others. Others described family health history communication as one-way or unreciprocated by younger family members who appeared uninterested or unwilling to share personal and family health information. The communication patterns that the authors identified are consistent with communication privacy management theory and with findings from studies focused on genetic testing results for hereditary conditions, suggesting that individuals are consistent in their communication of health and genetic risk information. Findings may guide the development of health message strategies for African Americans to increase family health history communication.

Impact of realistic communications for fast-acting demand side management

DEFF Research Database (Denmark)

Dambrauskas, Paulius; Syed, Mazheruddin H.; Blair, Steven M.

2017-01-01

The rising penetration of intermittent energy resources is increasing the need for more diverse electrical energy resources that are able to support ancillary services. Demand side management (DSM) has a significant potential to fulfil this role, but several challenges are still impeding the wide......-scale integration of DSM. One of the major challenges is ensuring the performance of the networks that enable communications between control centres and the end DSM resources. This study presents an analysis of all communications networks that typically participate in the activation of DSM, and provides an estimate...... for the overall latency that these networks incur. The most significant sources of delay from each of the components of the communications network are identified which allows the most critical aspects to be determined. This analysis, therefore, offers a detailed evaluation of the performance of DSM resources...

A Pattern Construction Scheme for Neural Network-Based Cognitive Communication

Directory of Open Access Journals (Sweden)

Ozgur Orcay

2011-01-01

Full Text Available Inefficient utilization of the frequency spectrum due to conventional regulatory limitations and physical performance limiting factors, mainly the Signal to Noise Ratio (SNR, are prominent restrictions in digital wireless communication. Pattern Based Communication System (PBCS is an adaptive and perceptual communication method based on a Cognitive Radio (CR approach. It intends an SNR oriented cognition mechanism in the physical layer for improvement of Link Spectral Efficiency (LSE. The key to this system is construction of optimal communication signals, which consist of encoded data in different pattern forms (waveforms depending on spectral availabilities. The signals distorted in the communication medium are recovered according to the pre-trained pattern glossary by the perceptual receiver. In this study, we have shown that it is possible to improve the bandwidth efficiency when largely uncorrelated signal patterns are chosen in order to form a glossary that represents symbols for different length data groups and the information can be recovered by the Artificial Neural Network (ANN in the receiver site.

Machine learning for identifying demand patterns of home energy management systems with dynamic electricity pricing

NARCIS (Netherlands)

Koolen, D. (Derck); Sadat-Razavi, N. (Navid); W. Ketter (Wolfgang)

2017-01-01

textabstractEnergy management plays a crucial role in providing necessary system flexibility to deal with the ongoing integration of volatile and intermittent energy sources. Demand Response (DR) programs enhance demand flexibility by communicating energy market price volatility to the end-consumer.

Power Terminal Communication Access Network Monitoring System Scheme Based on Design Patterns

Science.gov (United States)

Yan, Shengchao; Wu, Desheng; Zhu, Jiang

2018-01-01

In order to realize patterns design for terminal communication monitoring system, this paper introduces manager-workers, tasks-workers design patterns, based on common design patterns such as factory method, chain of responsibility, facade. Using these patterns, the communication monitoring system which combines module-groups like networking communication, business data processing and the peripheral support has been designed successfully. Using these patterns makes this system have great flexibility and scalability and improves the degree of systematic pattern design structure.

Daily patterns of communication and contact between Italian early adolescents and their friends.

Science.gov (United States)

Baiocco, Roberto; Laghi, Fiorenzo; Schneider, Barry H; Dalessio, Maria; Amichai-Hamburger, Yair; Coplan, Robert J; Koszycki, Diana; Flament, Martine

2011-01-01

The goal of the present study was to explore patterns of communication between adolescents and their friends across both "online" and "in-person" contexts. The participants were adolescents (n = 727) aged 11-16 years attending middle schools in urban and rural areas of Italy. Participants completed daily logs of their in-person and online contacts with friends for 20 consecutive school days. Girls reported more total contacts with their friends than did boys as well as friendships that were closer and more intimate. However, boys indicated more contact than girls via electronic communication and online. Contacts with peers in general were less frequent among the older participants, perhaps because of increasing academic demands. Participants who complemented in-person contact with friends with electronic contact were less lonely than their counterparts who were less versatile in accessing different modalities of making contact with friends.

Transient myocardial ischemia after abrupt withdrawal of antianginal therapy in chronic stable angina

DEFF Research Database (Denmark)

Egstrup, K

1988-01-01

In 47 patients with chronic stable angina and proven coronary artery disease, abrupt withdrawal of beta-adrenoceptor blocking agents either as monotherapy or in combination with calcium antagonists (group 1, n = 25) was compared with abrupt withdrawal of calcium antagonist monotherapy (group 2, n...... less than 0.05). These results indicate that a rebound increase in ischemic activity (mainly silent) occurs after abrupt withdrawal of beta-receptor blockade in patients with chronic stable angina. This increase in ischemic activity may be caused by increased myocardial oxygen demand....

It Takes Two: Sexual Communication Patterns and the Sexual and Relational Adjustment of Couples Coping With Provoked Vestibulodynia.

Science.gov (United States)

Rancourt, Kate M; Flynn, Michelle; Bergeron, Sophie; Rosen, Natalie O

2017-03-01

Provoked vestibulodynia (PVD) is a prevalent vulvovaginal pain condition that is associated with sexual and relational consequences for women and their partners. Greater perceived quality of sexual communication has been associated with women's lower pain during intercourse and with couples' better sexual and relational well-being. Whether couples' collaborative (eg, expressing feelings or problem solving) and negative (eg, withdrawing or criticizing) sexual communication patterns (SCPs) are differentially associated with couples' adjustment to PVD is unknown. To examine associations between collaborative and negative SCPs and women's pain and the sexual and relationship adjustment of women with PVD and their partners. Women diagnosed with PVD (N = 87) and their partners completed the Sexual Communication Patterns Questionnaire and measurements of pain (women only), sexual functioning, sexual satisfaction, sexual distress, and relationship satisfaction. (i) Numerical rating scale of pain during intercourse, (ii) Female Sexual Function Index and International Index of Erectile Function, (iii) Global Measure of Sexual Satisfaction, (iv) Female Sexual Distress Scale-Revised, and (v) Couple Satisfaction Index. When women reported greater collaborative SCP, they also reported higher sexual and relationship satisfaction. When women reported greater negative SCP, they reported less relationship satisfaction and had partners who reported greater sexual distress. When partners reported greater collaborative SCP, they also reported higher relationship satisfaction and had female partners who were less sexually distressed. When partners reported higher negative SCP, they also reported less relationship satisfaction. There were no associations between SCP and women's or partners' sexual functioning or women's pain. Collaborative SCP may benefit couples' sexual and relational well-being, whereas negative SCP may impede sexual and relational adjustment to PVD. Findings

CORRELATION BETWEEN FAMILY COMMUNICATION PATTERNS AND JUVENILE DELINQUENCY IN JUNIOR HIGH SCHOOL

Directory of Open Access Journals (Sweden)

Zurriyatun Thoyibah

2017-08-01

Full Text Available Background: Adolescents who are in transition period have high risk behavior of juvenile delinquency. Communication between parents and adolescents effectively and openly could help adolescents to avoid delinquency behavior. Objective: This study aims to examine the relationship between family communication patterns and juvenile delinquency in Junior High School. Methods: This research employed a cross-sectional design with correlation description approach. There were 243 students selected using simple random sampling from the 7th and 8th grade students of Junior High School. A questionnaire of juvenile delinquency and family communication pattern were used in this study. Data were analyzed using Chi Square test. Result: The research showed that the majority juvenile delinquency category was low (65% and the majority of communication pattern was in functional category (73.3%. There was a significant relationship between family communication pattern and juvenile delinquency (p<0.05. Conclusion: Communication pattern within family have significant association with juvenile delinquency.

A demand assignment control in international business satellite communications network

Science.gov (United States)

Nohara, Mitsuo; Takeuchi, Yoshio; Takahata, Fumio; Hirata, Yasuo

An experimental system is being developed for use in an international business satellite (IBS) communications network based on demand-assignment (DA) and TDMA techniques. This paper discusses its system design, in particular from the viewpoints of a network configuration, a DA control, and a satellite channel-assignment algorithm. A satellite channel configuration is also presented along with a tradeoff study on transmission rate, HPA output power, satellite resource efficiency, service quality, and so on.

18 CFR 806.23 - Standards for water withdrawals.

Science.gov (United States)

2010-04-01

...) Investigate additional sources or storage options to meet the demand of the project. (ii) Submit a water... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Standards for water withdrawals. 806.23 Section 806.23 Conservation of Power and Water Resources SUSQUEHANNA RIVER BASIN...

Stochastic demand patterns for Markov service facilities with neutral and active periods

International Nuclear Information System (INIS)

Csenki, Attila

2009-01-01

In an earlier paper, a closed form expression was obtained for the joint interval reliability of a Markov system with a partitioned state space S=U union D, i.e. for the probability that the system will reside in the set of up states U throughout the union of some specific disjoint time intervals I l =[θ l ,θ l +ζ l ],l=1,...,k. The deterministic time intervals I l formed a demand pattern specifying the desired active periods. In the present paper, we admit stochastic demand patterns by assuming that the lengths of the active periods, ζ l , as well as the lengths of the neutral periods, θ l -(θ l-1 +ζ l-1 ), are random. We explore two mechanisms for modelling random demand: (1) by alternating renewal processes; (2) by sojourn times of some continuous time Markov chain with a partitioned state space. The first construction results in an expression in terms of a revised version of the moment generating functions of the sojourns of the alternating renewal process. The second construction involves the probability that a Markov chain follows certain patterns of visits to some groups of states and yields an expression using Kronecker matrix operations. The model of a small computer system is analysed to exemplify the ideas

E-mail communication patterns and job burnout

Science.gov (United States)

2018-01-01

A considerable body of research has documented the negative effects of job burnout on employees and their organizations, emphasizing the importance of the identification of early signs of the phenomenon for the purposes of prevention and intervention. However, such timely identification is difficult due to the time and cost of assessing the burnout levels of all employees in an organization using established scales. In this paper, we propose an innovative way to identify employees at risk of job burnout by analyzing their e-mail communication patterns. Building on the Job Demands–Resources model, we theorize about the relationship between e-mail communication patterns and levels of employee exhaustion and disengagement (two dimensions of burnout). We analyzed 52,190 e-mails exchanged between 57 employees of a medium sized R&D company over a five-month period. We then related these employees’ communication patterns to their levels of burnout, collected using an established scale (the OLBI–Oldenburg Burnout Inventory). Our results provide support for the overall proposition of the paper, that e-mail communications can be used to identify individuals at risk of job burnout. Our models explain up to 34% of the variance of burnout and up to 37% and 19% respectively of the variance of exhaustion and disengagement. They also successfully distinguish between employees with a higher risk of burnout and those with lower levels of risk (F1 score of 84% with recall of 100% and 73% precision). We discuss the implications of our results and present suggestions for future research. PMID:29518128

ТYPES OF BRAIN INTERHEMISPHERIC ORGANIZATION PROFILE AND INDEX OF DEMAND OF COMMUNICATION, DEMAND OF ACHIEVEMENT, ANXIETY AND APPREHENSION OF STUDENTS-PHYSICIANS I-III COURCES

Directory of Open Access Journals (Sweden)

Irina Evgen’evna Kononez

2017-10-01

Full Text Available Background: Definition of percentage of profile versions of lateral brain organization; index of demand of communication, demand of achievement, anxiety and apprehension of students – physicians. Materials and methods: Method of E.D. Homskaya, 1997 [19]; scheme «hand-leg-ear-eye»; methodic on J. Teilor, (N.M. Peisahov, 1977 [12]. Results: Studied profile versions of lateral brain organization (LBO on the scheme «hand-leg-ear-eye» and index of demand of communication (DC, demand of achievement (DA, level of anxiety and apprehension (AA of 320 students-physicians of I–III courses of faculty «General medicine» of the Kyrgyz State Medical Academy in the age from 18 to 22. Revealed that to the third year of study increased versions with left signs of LBO with testees. Level of anxiety-apprehension (AA with the first grade students is truly higher in compare with students of II-III courses, at that index of girls AA truly increases index than boys. Index of DS is higher with only right-handers in compare with mixed types of LBO, and index of DC are more higher than mixed types of LBO, only right-handers are more anxiety than mixed types. Results of research can render assistance in development of practical recommendations for optimization of educational process. Conclusion: 1. To the third year of study increased versions with left signs of profile of lateral brain organization with testees. 2. Index of anxiety-apprehension on the 1 grade are truly higher in compare with students of II–III cources. 3. Index of demand of communication with only right-handers increase index with persons with mixed types of profiles of lateral organization, and demand of achievement is higher than mixed types of LBO. Only right-handers are more anxiety than mixed types.

Communication with parents concerning withholding or withdrawing of life-sustaining interventions in neonatology.

Science.gov (United States)

Janvier, Annie; Barrington, Keith; Farlow, Barbara

2014-02-01

The nature and content of the conversations between the healthcare team and the parents concerning withholding or withdrawing of life-sustaining interventions for neonates vary greatly. These depend upon the status of the infant; for some neonates, death may be imminent, while other infants may be relatively stable, yet with a potential risk for surviving with severe disability. Healthcare providers also need to communicate with prospective parents before the birth of premature infants or neonates with uncertain outcomes. Many authors recommend that parents of fragile neonates receive detailed information about the potential outcomes of their children and the choices they have provided in an unbiased and empathetic manner. However, the exact manner this is to be achieved in clinical practice remains unclear. Parents and healthcare providers may have different values regarding the provision of life-sustaining interventions. However, parents base their decisions on many factors, not just probabilities. The role of emotions, regret, hope, quality of life, resilience, and relationships is rarely discussed. End-of-life discussions with parents should be individualized and personalized. This article suggests ways to personalize these conversations. The mnemonic "SOBPIE" may help providers have fruitful discussions: (1) What is the Situation? Is the baby imminently dying? Should withholding or withdrawing life-sustaining interventions be considered? (2) Opinions and options: personal biases of healthcare professionals and alternatives for patients. (3) Basic human interactions. (4) Parents: their story, their concerns, their needs, and their goals. (5) Information: meeting parental informational needs and providing balanced information. (6) Emotions: relational aspects of decision making which include the following: emotions, social supports, coping with uncertainty, adaptation, and resilience. In this paper, we consider some aspects of this complex process. Copyright �

Significance and basic patterns of risk communication

International Nuclear Information System (INIS)

Obermeier, O.P.

1996-01-01

The philosophically coloured paper on the aspects of risk communication patterns in society shows that debates about risks are governed by a number of stereotype characters representing the individualist and manager type, bureaucracy and law-and-order type, ego-centered embarrassment activist, and fundamentalist. Every risk-relevant group in the study tries to push forward its own interests. Risk communication is understood as a process of social dealing. (HP) [de

17 CFR 41.47 - Withdrawal of margin.

Science.gov (United States)

2010-04-01

... PRODUCTS Customer Accounts and Margin Requirements § 41.47 Withdrawal of margin. (a) By the customer... positions in the account under this Regulation (Subpart E, §§ 41.42 through 41.49). (b) By the security...) Interest charged on credit maintained in the account; (3) Communication or shipping charges with respect to...

Satellite communications - Intelsat and global patterns

Science.gov (United States)

Astrain, S.

1983-10-01

The global pattern of mankind's population growth is examined, taking into account the exponential increase in population which began only in the 17th century. As world population has grown, trade has increased, and transportation and communications have become vitally important. A revolution in global communications was initiated when Intelsat launched the first international communications satellite, 'Early Bird', in April 1965. Since April 1965, a tremendous development in global communications by means of satellites has taken place. The Intelsat VI satellite will have a capacity of 36,000 telephone circuits plus 2 TV channels, while the capacity of Early Bird was only 240 telephone circuits. Today, Intelsat is truly an international organization which includes 108 member countries. Attention is given to the particular importance of the Intelsat services to the developing countries, the exploration of new technologies and system concepts, and the extension of services to those portions of the global village which have remained electronically isolated.

18 CFR 801.3 - Allocations, diversions, withdrawals and release.

Science.gov (United States)

2010-04-01

... wherein the demands upon supply made by water users have developed or threaten to develop to such a degree..., or withdrawals of water be based on the common law principles of riparian rights which entitles... actual and immediate shortage of available and usable water supply, determine and delineate the area of...

18 CFR 430.13 - Protected area permits for new withdrawals.

Science.gov (United States)

2010-04-01

... space heating or cooling that are subsequently used for commercial or industrial water supply purposes... against significant leaks of refrigerant, all ground water heat pump systems shall be equipped with an... resource requirements; evaluate supply-side and demand-side alternatives to meet water withdrawal needs...

Effects of Daily Morphine Administration and Deprivation on Choice and Demand for Remifentanil and Cocaine in Rhesus Monkeys

Science.gov (United States)

Wade-Galuska, Tammy; Galuska, Chad M.; Winger, Gail

2011-01-01

Choice procedures have indicated that the relative reinforcing effectiveness of opioid drugs increases during opioid withdrawal. The demand curve, an absolute measure of reinforcer value, has not been applied to this question. The present study assessed whether mild morphine withdrawal would increase demand for or choice of remifentanil or…

Nicotine Withdrawal Induces Neural Deficits in Reward Processing.

Science.gov (United States)

Oliver, Jason A; Evans, David E; Addicott, Merideth A; Potts, Geoffrey F; Brandon, Thomas H; Drobes, David J

2017-06-01

Nicotine withdrawal reduces neurobiological responses to nonsmoking rewards. Insight into these reward deficits could inform the development of targeted interventions. This study examined the effect of withdrawal on neural and behavioral responses during a reward prediction task. Smokers (N = 48) attended two laboratory sessions following overnight abstinence. Withdrawal was manipulated by having participants smoke three regular nicotine (0.6 mg yield; satiation) or very low nicotine (0.05 mg yield; withdrawal) cigarettes. Electrophysiological recordings of neural activity were obtained while participants completed a reward prediction task that involved viewing four combinations of predictive and reward-determining stimuli: (1) Unexpected Reward; (2) Predicted Reward; (3) Predicted Punishment; (4) Unexpected Punishment. The task evokes a medial frontal negativity that mimics the phasic pattern of dopaminergic firing in ventral tegmental regions associated with reward prediction errors. Nicotine withdrawal decreased the amplitude of the medial frontal negativity equally across all trial types (p nicotine dependence (p Nicotine withdrawal had equivocal impact across trial types, suggesting reward processing deficits are unlikely to stem from changes in phasic dopaminergic activity during prediction errors. Effects on tonic activity may be more pronounced. Pharmacological interventions directly targeting the dopamine system and behavioral interventions designed to increase reward motivation and responsiveness (eg, behavioral activation) may aid in mitigating withdrawal symptoms and potentially improving smoking cessation outcomes. Findings from this study indicate nicotine withdrawal impacts reward processing signals that are observable in smokers' neural activity. This may play a role in the subjective aversive experience of nicotine withdrawal and potentially contribute to smoking relapse. Interventions that address abnormal responding to both pleasant and

An Analysis on change of household electricity demand pattern

Energy Technology Data Exchange (ETDEWEB)

Na, In Gang [Korea Energy Economics Institute, Euiwang (Korea)

1999-01-01

The object of this study is to analyze the behavioral pattern change of household electricity demand. Through the cross section analysis using materials from the energy total research report, the change in income elasticity of household electricity demand was studied. In this study, two methodologies were used. Firstly, it was shown that the effect of an income variable was very significant with a positive value in simultaneous equations model using exponential equations of electrical appliances holding. Cross section income effect showed a various distribution according to the season or income level. Overall, it was calculated at 0.111 when the appliances are fixed and 0.432 when even appliances are changed. Secondly, using a choice convenient correction model, it is resulted that lambda, the choice convenient correction factor, has a positive value and is statistically significant. In 1996, income elasticity of electricity demand for households with air-conditioning was 0.305 and for households without air-conditioning was 0.172. Income elasticity of households with air-conditioning is increasing as time goes by while income elasticity of households without air-conditioning is decreasing. (author). 32 refs., 35 tabs.

The Effect of Family Communication Patterns on Adopted Adolescent Adjustment

Science.gov (United States)

Rueter, Martha A.; Koerner, Ascan F.

2008-01-01

Adoption and family communication both affect adolescent adjustment. We proposed that adoption status and family communication interact such that adopted adolescents in families with certain communication patterns are at greater risk for adjustment problems. We tested this hypothesis using a community-based sample of 384 adoptive and 208…

Demand pattern analysis of taxi trip data for anomalies detection and explanation

DEFF Research Database (Denmark)

Markou, Ioulia; Rodrigues, Filipe; Pereira, Francisco Camara

2017-01-01

Due to environmental and economic stress, strong investment exists now towards adaptive transport systems that can efficiently utilize capacity, minimizing costs and environmental impacts. The common vision is a system that dynamically changes itself (the supply) to anticipate traveler needs (the...... demand). In some occasions, unexpected and unwanted demand patterns are noticed in the traffic network that lead to system failures and cost implications. Significantly low speeds or excessively low flows at an unforeseeable time are only some of the phenomena that are often noticed and need...

A cross-cultural analysis of communication patterns between two ...

African Journals Online (AJOL)

Employing the mixed-method research design, the study revealed the cultural affinity in both ethnic groups' communication patterns in the use of honorific greeting, silence, expressiveness (direct or indirectness and touch) and eye contact. This shows that culture has a significant influence on some of the communication ...

Family communication patterns and teen drivers' attitudes toward driving safety.

Science.gov (United States)

Yang, Jingzhen; Campo, Shelly; Ramirez, Marizen; Krapfl, Julia Richards; Cheng, Gang; Peek-Asa, Corinne

2013-01-01

Family communication patterns (FCPs) play an important role in reducing the risk-taking behaviors of teens, such as substance use and safer sex. However, little is known about the relationship between family communication and teen driving safety. We analyzed the baseline data from a randomized trial that included 163 parent-teen dyads, with teens who would be receiving their intermediate driver's license within 3 months. FCPs were divided into four types-pluralistic, protective, consensual, and laissez-faire-and were correlated with the frequency of parent-teen discussions and teens' driving safety attitudes. The ratings on four types of FCPs were distributed quite evenly among teens and parents. Parents and teens agreed on their FCP ratings (p = .64). In families with communication patterns that were laissez-faire, protective, and pluralistic, parents talked to their teens less about safe driving than did parents in families with a consensual communication pattern (p < .01). Moreover, the frequency of parent-teen communication about safe driving was positively associated with teen attitudes toward safe driving (adjusted β = 0.35, p = .03). Health care providers need to encourage parents, particularly those with non-consensual FCPs, to increase frequency of parent-teen interactions. Copyright © 2013 National Association of Pediatric Nurse Practitioners. Published by Mosby, Inc. All rights reserved.

Infants in Drug Withdrawal: A National Description of Nurse Workload, Infant Acuity, and Parental Needs.

Science.gov (United States)

Smith, Jessica G; Rogowski, Jeannette A; Schoenauer, Kathryn M; Lake, Eileen T

Infants in drug withdrawal have complex physiological and behavioral states, requiring intensive nursing care. The study objectives were to describe acuity, parental needs, and nurse workload of infants in drug withdrawal compared with other infants. The design was cross-sectional and involved secondary nurse survey data from 6045 staff nurses from a national sample of 104 neonatal intensive care units. Nurses reported the care of 15 233 infants, 361 (2.4%) of whom were in drug withdrawal. Three-fourths of hospitals had at least 1 infant in drug withdrawal. In these hospitals, the mean number of infants in drug withdrawal was 4.7. Infant acuity was significantly higher among infants in drug withdrawal. Parents of infants in drug withdrawal required significantly more care to address complex social situations (51% vs 12%). The number of infants assigned to nurses with at least 1 infant in withdrawal (mean = 2.69) was significantly higher than typical (mean = 2.51). Given infant acuity and parental needs, policies legislating patient-to-nurse ratios should permit professional discretion on the number of patients to assign nurses caring for infants in drug withdrawal. Managers and charge nurses should consider the demands of caring for infants in drug withdrawal in assignment decisions and provide support and education.

Living antennas on communication satellites

DEFF Research Database (Denmark)

Lumholt, Michael

2003-01-01

Crises change the global pattern of communication. The communications problems occur because the satellites are optimized to cover specific geographic areas, and these areas cannot be altered once the satellites are in Earth orbit. An effective solution to the problem is to equip communication sa...... satellites with "living" antennas that can adjust their radiation coverage areas according to the new demands. The development of living antennas is, therefore, among the focus areas identified and supported by the European Space Agency, ESA....

Perceived information and communication technology (ICT) demands on employee outcomes: the moderating effect of organizational ICT support.

Science.gov (United States)

Day, Arla; Paquet, Stephanie; Scott, Natasha; Hambley, Laura

2012-10-01

Although many employees are using more information communication technology (ICT) as part of their jobs, few studies have examined the impact of ICT on their well-being, and there is a lack of validated measures designed to assess the ICT factors that may impact employee well-being. Therefore, we developed and validated a measure of ICT demands and supports. Using Exploratory Structural Equation Modeling, we found support for 8 ICT demands (i.e., availability, communication, ICT control, ICT hassles, employee monitoring, learning, response expectations, and workload) and two facets of ICT support (personal assistance and resources/upgrades support). Jointly, the ICT demands were associated with increased strain, stress, and burnout and were still associated with stress and strain after controlling for demographics, job variables, and job demands. The two types of ICT support were associated with lower stress, strain, and burnout. Resources/upgrades support moderated the relationship between learning expectations and most strain outcomes and between ICT hassles and strain. Personal assistance support moderated the relationship between ICT hassles and strain.

Information and Communications Systems for Control-by-Price of Distributed Energy Resources and Flexible Demand

OpenAIRE

Nyeng, Preben; Østergaard, Jacob

2011-01-01

The control-by-price concept fits well with controlling small-scale generation, storage and demand. In this paper, we investigate the required information and communications systems that are needed to realize the control-by-price concept for such units. We first present a proposal for overall infrastructure and subsystem design and secondly focus on the design and implementation of the end-user price-responsive controller, interfaces, and communications. The design and its applicability on ex...

The oil industry in Latin America: changing demand patterns and deregulation

International Nuclear Information System (INIS)

Thaler, Harald.

1997-02-01

The Oil Industry in Latin America: changing demand patterns and deregulation analyses the common problems faced by countries in the region in modernising and developing their oil sectors, despite the great variation in domestic natural resources between them. It highlights areas of potential, as well as clearly indicating risks and possible bureaucratic and political problems. (author)

Telehone consultations: At the emergency service, Copenhagen County: Analysis of doctor-patient communication patterns

DEFF Research Database (Denmark)

Larsen, Jan-Helge; Risør, Ole

1997-01-01

Communications patterns, emergency service, out-of-hours service, telehpone consultations, video-supervision......Communications patterns, emergency service, out-of-hours service, telehpone consultations, video-supervision...

Agricultural activity shapes the communication and migration patterns in Senegal

Science.gov (United States)

Martin-Gutierrez, S.; Borondo, J.; Morales, A. J.; Losada, J. C.; Tarquis, A. M.; Benito, R. M.

2016-06-01

The communication and migration patterns of a country are shaped by its socioeconomic processes. The economy of Senegal is predominantly rural, as agriculture employs over 70% of the labor force. In this paper, we use mobile phone records to explore the impact of agricultural activity on the communication and mobility patterns of the inhabitants of Senegal. We find two peaks of phone calls activity emerging during the growing season. Moreover, during the harvest period, we detect an increase in the migration flows throughout the country. However, religious holidays also shape the mobility patterns of the Senegalese people. Hence, in the light of our results, agricultural activity and religious holidays are the primary drivers of mobility inside the country.

Impacts of Seasonal Patterns of Climate on Recurrent Fluctuations in Tourism Demand: Evidence from Aruba

NARCIS (Netherlands)

Ridderstaat, J.R.; Oderber, M.; Croes, R.; Nijkamp, P.; Martens, P.

2014-01-01

This study estimates the effect of seasonal patterns of pull and push climate elements (rainfall, temperature, wind, and cloud coverage) on recurrent fluctuations in tourism demand from the United States (USA) and Venezuela to Aruba. The seasonal patterns were first isolated from the series using

Object relations, reality testing, and social withdrawal in schizophrenia and bipolar disorder.

Science.gov (United States)

Hansen, Charlotte Fredslund; Torgalsbøen, Anne-Kari; Røssberg, Jan Ivar; Romm, Kristin Lie; Andreassen, Ole Andreas; Bell, Morris D; Melle, Ingrid

2013-03-01

In this study, we investigated the relationships between observed social withdrawal (Positive and Negative Syndrome Scale [PANSS] Passive Social Withdrawal and PANSS Active Social Avoidance), subjectively experienced social withdrawal (Social Functioning Scale [SFS] Withdrawal and SFS Interpersonal Behavior), and their associations to the underlying psychological patterns of Object Relations and Reality Testing. Patients with schizophrenia (n = 55) and bipolar disorder (n = 51) from the ongoing Thematically Organized Psychosis project, Oslo University Hospital, Norway, were evaluated using the Bell Object Relations and Reality Testing Inventory, the PANSS, and the SFS. Object relations and reality testing subscales related differentially to PANSS Passive Social Withdrawal and PANSS Active Social Avoidance. These two measures, together with the level of alienation, explained a significant amount of variance in self-experienced social dysfunction. Findings reveal the multidimensional nature of social dysfunction in severe mental disorders.

Electricity deregulation, spot price patterns and demand-side management

International Nuclear Information System (INIS)

Li, Y.; Flynn, P.C.

2006-01-01

This paper examines extensive hourly or half-hourly power price data from 14 deregulated power markets. It analyzes average diurnal patterns, relationship to system load, volatility, and consistency over time. Diurnal patterns indicate the average price spread between off-peak and on-peak and weekend vs. weekday power consumption. Volatility is measured by price velocity: the average normalized hourly change in power price, calculated daily. The calculated price velocity is broken down into an expected component that arises from the diurnal pattern and an unexpected component that arises from unknown factors. The analysis reveals significant differences among markets, suggesting that demand-side management (DSM) of power consumption is far more difficult in some markets than in others. At one extreme, Spain, Britain and Scandinavia show consistent diurnal price patterns, a stable relationship between price and system load, and a low unexplained component of price volatility. A power consumer in these markets could form a reasonable expectation of a reward for DSM of elective power consumption. At the other extreme, two markets in Australia show erratic diurnal price patterns from year to year, low correlation between price and system load, and a high amount of unexpected price velocity. A power consumer in these markets would have far greater difficulty in realizing a benefit from DSM. Markets that experienced one period of very high prices without a clear external cause, such as California and Alberta, appear to have a significant longer-term erosion of public support for deregulation. (author)

Associations between Family Communication Patterns, Sibling Closeness, and Adoptive Status

Science.gov (United States)

Samek, Diana R.; Rueter, Martha A.

2011-01-01

Previous research has demonstrated the protective effect of family and sibling closeness on child adjustment, but fewer studies have investigated how closeness is promoted within families. Guided by Family Communication Patterns Theory, we tested the association between family communication and sibling emotional and behavioral closeness, and…

Use of Taxi-Trip Data in Analysis of Demand Patterns for Detection and Explanation of Anomalies

DEFF Research Database (Denmark)

Markou, Ioulia; Rodrigues, Filipe; Pereira, Francisco Camara

2017-01-01

Because of environmental and economic stress, current strong investment in adaptive transport systems can efficiently use capacity, minimizing costs and environmental impacts. The common vision is of a system that dynamically changes itself (the supply) to anticipate the needs of travelers (the...... demand). In some occasions, unexpected and unwanted demand patterns are noticed in the traffic network; these patterns lead to system failures and cost implications. Significantly, low speeds or excessively low flows at an unforeseeable time are only some of the phenomena that are often noticed and need...

An Empirical Analysis on Individuals’ DepositWithdrawal Behaviors Using Data Collected through a Web-Based Survey

Directory of Open Access Journals (Sweden)

Toshihiko TAKEMURA

2009-11-01

Full Text Available The purpose of this paper is to investigate relationships between individual depositor behaviors, as to whether they will withdraw all of their deposits, and factors behind them such as the degree of trust in information sources, frequency of communication, individuals' transaction with banks, and individuals’ attributes. By doing so, we suggest possible countermeasures whereby depositors will not excessively withdraw their deposits after receiving uncertain information on the financial environment. In this paper, we analyze the relationships by using data collected through a Web-based survey. The results were as follows: First, individuals who trust in information sources such as weekly/monthly magazines, the Internet, and conversations with people at workplace would be more likely to withdraw their deposits. Second, increases in phone calls with friends and in communication frequency at neighborhood and workplaces also make depositors to withdraw funds. Third, their tendency to withdraw deposits is affected by the individuals’ attributes such as gender and education. As the recognition of the deposit insurance scheme among people seems to affect their behavior according to our analysis, we suggest that it is better that authorities advertise the function of deposit insurance schemes to prevent depositors from getting into a panic situation like bank run.

Phase patterns of coupled oscillators with application to wireless communication

Energy Technology Data Exchange (ETDEWEB)

Arenas, A.

2008-01-02

Here we study the plausibility of a phase oscillators dynamical model for TDMA in wireless communication networks. We show that emerging patterns of phase locking states between oscillators can eventually oscillate in a round-robin schedule, in a similar way to models of pulse coupled oscillators designed to this end. The results open the door for new communication protocols in a continuous interacting networks of wireless communication devices.

Demand Moderation in Military Communication Networks

National Research Council Canada - National Science Library

Blackmore, Perry

2002-01-01

.... Demand moderation is the term used to encompass the array of mechanisms aimed at achieving this end. Integrated Defence networks of the future should benefit enormously from demand moderation mechanisms.

Communication Pattern And Skill Of Leaders In Private University Management

OpenAIRE

Ani Yuningsih; Dadan Mulyana

2017-01-01

Communication strategies and skills supported by mutually supportive management tools are one of the managerial skills that must be mastered by private university (PTS) leaders. Leadership communication skills and style will form organizational communication patterns that will become the foundation for a healthy and effective organizational climate to develop its vision and mission. This research is done by using case study method at some PTS which is representation of PTS profile in West Jav...

Assessment of demand-response-driven load pattern elasticity using a combined approach for smart households

NARCIS (Netherlands)

Paterakis, N.G.; Tascikaraoglu, A.; Erdinç, O.; Bakirtzis, A.G.; Catalaõ, J.P.S.

2016-01-01

The recent interest in the smart grid vision and the technological advancement in the communication and control infrastructure enable several smart applications at different levels of the power grid structure, while specific importance is given to the demand side. As a result, changes in load

Preparing Nursing and Social Work Students to Care for Patients in Acute Alcohol Withdrawal.

Science.gov (United States)

Gates, Sharon A; Brown, James R

Alcohol and other drug abuse has become a national crisis with approximately 26% of general medical patients having alcohol-related problems. New nurses and social workers are often not prepared to care for patients with severe alcohol withdrawal symptoms because they lack experience in actual crisis situations. The purpose of this study was to prepare nursing and social work students to care for a patient undergoing an acute alcohol withdrawal process. Nine groups of 8-10 students participated in a 2.5-hour simulation event that included an alcohol withdrawal seizure, team meeting, and discharge of the patient. Students recognized the importance of all the professional roles and how each professional benefits patient care. Before the simulation, students thought they were prepared to care for patients experiencing alcohol withdrawal; however, the crisis of an alcohol seizure decreased the student's ability to perform skills and communicate effectively. These findings suggest that new nurses and social workers may not be prepared to care for the acute alcohol withdrawal patient.

[An examination of the determinants of social withdrawal and affinity for social withdrawal].

Science.gov (United States)

Watanabe, Asami; Matsui, Yutaka; Takatsuka, Yusuke

2010-12-01

This study examined the determinants of social withdrawal using data from a survey by the Tokyo Metropolitan Government Office for Youth Affairs and Public Safety (2008). In addition, this study identified young people who showed an affinity for social withdrawal although they were not in a state of withdrawal, and examined the determinants of an affinity for social withdrawal. The results of stepwise discriminant analysis showed that factors such as social phobia, depression, violence, and emotional bonds with family differentiated between the general youth group and the social withdrawal group and the "affinity group". Social phobia, violence, and refusal to be interfered in self-decision making differentiated between the social withdrawal group and the "affinity group". This study shows that an "affinity group" should be cared as well as an actual withdrawal group.

Different stability of social-communication problems and negative demanding behaviour from infancy to toddlerhood in a large Dutch population sample

Science.gov (United States)

2014-01-01

Background Little is known about the stability of behavioural and developmental problems as children develop from infants to toddlers in the general population. Therefore, we investigated behavioural profiles at two time points and determined whether behaviours are stable during early development. Methods Parents of 4,237 children completed questionnaires with 62 items about externalizing, internalizing, and social-communicative behaviour when the children were 14–15 and 36–37 months old. Factor mixture modelling identified five homogeneous profiles at both time points: three with relatively normal behaviour or with mild/moderate problems, one with clear communication and interaction problems, and another with pronounced negative and demanding behaviour. Results More than 85% of infants with normal behaviour or mild problems at 14–15 months were reported to behave relatively typically as toddlers at 36–37 months. A similar percentage of infants with moderate communication problems outgrew their problems by the time they were toddlers. However, infants with severe problems had mild to severe problems as toddlers, and did not show completely normal behaviour. Improvement over time occurred more often in children with negative and demanding behaviour than in children with communication and interaction problems. The former showed less homotypic continuity than the latter. Conclusions Negative and demanding behaviour is more often transient and a less specific predictor of problems in toddlerhood than communication and interaction problems. PMID:25061477

A critical period of progesterone withdrawal precedes menstruation in macaques

Science.gov (United States)

Slayden, Ov D; Brenner, Robert M

2006-01-01

Macaques are menstruating nonhuman primates that provide important animal models for studies of hormonal regulation in the uterus. In women and macaques the decline of progesterone (P) at the end of the cycle triggers endometrial expression of a variety of matrix metalloproteinase (MMP) enzymes that participate in tissue breakdown and menstrual sloughing. To determine the minimal duration of P withdrawal required to induce menses, we assessed the effects of adding P back at various time points after P withdrawal on both frank bleeding patterns and endometrial MMP expression. Artificial menstrual cycles were induced by treating the animals sequentially with implants releasing estradiol (E2) and progesterone (P). To assess bleeding patterns, P implants were removed at the end of a cycle and then added back at 12, 24, 30, 36, 40, 48, 60, or 72 hours (h) after the initial P withdrawal. Observational analysis of frank bleeding patterns showed that P replacement at 12 and 24 h blocked menses, replacement at 36 h reduced menses but replacement after 36 h failed to block menses. These data indicate that in macaques, a critical period of P withdrawal exists and lasts approximately 36 h. In other similarly cycled animals, we withdrew P and then added P back either during (12–24 h) or after (48 h) the critical period, removed the uterus 24 h after P add back and evaluated endometrial MMP expression. Immunocytochemistry showed that replacement of P during the critical period suppressed MMP-1, -2 and -3 expression along with menses, but replacement of P at 48 h, which failed to suppress mense, suppressed MMP-1 and MMP-3 but did not block MMP-2. We concluded that upregulation of MMPs is essential to menses induction, but that after the critical period, menses will occur even if some MMPs are experimentally blocked. PMID:17118170

Treatment for amphetamine withdrawal.

Science.gov (United States)

Shoptaw, Steven J; Kao, Uyen; Heinzerling, Keith; Ling, Walter

2009-04-15

Few studies examined treatments for amphetamine withdrawal, although it is a common problem among amphetamine users. Its symptoms, in particular intense craving, may be a critical factor leading to relapse to amphetamine use. In clinical practice, medications for cocaine withdrawal are commonly used to manage amphetamine withdrawal although the pharmacodynamic and pharmacokinetic properties of these two illicit substances are different. To assess the effectiveness of pharmacological alone or in combination with psychosocial treatment for amphetamine withdrawals on discontinuation rates, global state, withdrawal symptoms, craving, and other outcomes. MEDLINE (1966 - 2008), CINAHL (1982 - 2008), PsycINFO (1806 - 2008), CENTRAL (Cochrane Library 2008 issue 2), references of obtained articles. All randomised controlled and clinical trials evaluating pharmacological and or psychosocial treatments (alone or combined) for people with amphetamine withdrawal symptoms. Two authors evaluated and extracted data independently. The data were extracted from intention-to-treat analyses. The Relative Risk (RR) with the 95% confidence interval (95% CI) was used to assess dichotomous outcomes. The Weighted Mean Difference (WMD) with 95% CI was used to assess continuous outcomes. Four randomised controlled trials (involving 125 participants) met the inclusion criteria for the review. Two studies found that amineptine significantly reduced discontinuation rates and improved overall clinical presentation, but did not reduce withdrawal symptoms or craving compared to placebo. The benefits of mirtazapine over placebo for reducing amphetamine withdrawal symptoms were not as clear. One study suggested that mirtazapine may reduce hyperarousal and anxiety symptoms associated with amphetamine withdrawal. A more recent study failed to find any benefit of mirtazapine over placebo on retention or on amphetamine withdrawal symptoms. No medication is effective for treatment of amphetamine

Exploring the Pattern of Internal Communication in Total Quality Management Implementation in Manufacturing Companies

Directory of Open Access Journals (Sweden)

Samsudin Sharina

2017-01-01

Full Text Available Communication is an important aspect of organizational dynamic process and it is irrefutable one of the critical success factors of the Total Quality Management (TQM implementation. Although there are increasing awareness concerning the importance of internal organizational communication, knowledge appears to have rarely translated into practice or there is lack of guidance to effectively practicing it. Therefore, a study was proposed to investigate the pattern of internal communication practice in TQM implementation. This paper concerns on focusing into internal communication practices in TQM implementation factors and the communication patterns in terms of message forms and mediums of communication to convey TQM messages. Reliability and Factor analysis were carried out to confirm items that form each factor in internal communication in TQM implementation. Based on the analysis of survey questionnaires distributed to 104 large manufacturing companies implementing TQM in Malaysia, it was found that there are certain communication patterns practice by the management when conveying and disseminating TQM messages, but they have no specific guidelines. Therefore, the internal communication practices are not well planned. Finally, it is suggested that further research should be carried out to explain clearly the role and strategy of communication on this issue in order to boost the success of TQM implementation particularly in manufacturing company.

Residents' perceptions about surrogate decision makers' financial conflicts of interest in ventilator withdrawal.

Science.gov (United States)

Wastila, Lisa J; Farber, Neil J

2014-05-01

There have been no studies to date that examine physicians' decisions to withdraw life-sustaining treatment for patients based on their surrogates' financial gain. The authors' objective was to ascertain physician attitudes about withdrawing life-sustaining treatment when financial considerations are involved. A survey was developed and pretested containing eight scenarios in which a terminally ill patient's spouse had a decision to make regarding withdrawal of the ventilator, which was deemed medically futile. Nested variables included agreement or disagreement between the spouse and patient, decision to withdraw or continue the ventilator, and financial gain or no financial gain for the spouse. The authors surveyed all internal medicine residents at the University of California, San Diego in the autumn of 2011 and winter of 2012. The responses on each of the three variables for which respondents were likely to withdraw the ventilator were analyzed via student's t-tests. Residents were more likely to withdraw the ventilator when requested to do so than when it was requested to be continued. They were also more likely to withdraw the ventilator when there was agreement in the decision between the spouse and the patient. Residents were more likely to withdraw the ventilator when the spouse would not benefit financially. Internal medicine residents make some decisions about whether to withdraw life-sustaining treatment based on financial considerations. There needs to be ongoing communication with residents about end-of-life decisions where conflicts may exist between the surrogate decision makers and patients or physicians.

Opiate and opioid withdrawal

Science.gov (United States)

... opiate withdrawal; Oxycontin - opiate withdrawal; Hydrocodone - opiate withdrawal; Detox - opiates; Detoxification - opiates ... facilities set up to help people with detoxification (detox). In a regular hospital, if symptoms are severe. ...

Distinct neuronal activation patterns are associated with PCP-induced social withdrawal and its reversal by the endocannabinoid-enhancing drug URB597.

Science.gov (United States)

Matricon, Julien; Seillier, Alexandre; Giuffrida, Andrea

2016-09-01

The fatty acid amide hydrolase inhibitor, URB597, an endocannabinoid enhancing drug, reverses social withdrawal in the sub-chronic PCP rat model of schizophrenia, but reduces social interaction (SI) in controls. To identify the anatomical substrates associated with PCP-induced social withdrawal and the contrasting effects of URB597 on SI in PCP- versus saline-treated rats, we analyzed SI-induced c-Fos expression in 28 brain areas relevant to schizophrenia and/or social behavior following vehicle or URB597 administration. In saline-treated rats, SI was accompanied by changes in c-Fos expression in the infralimbic and orbitofrontal cortices, dorsomedial caudate putamen, ventrolateral nucleus of the septum, dorsolateral periaqueductal gray (dlPAG) and central amygdala. Except for the dlPAG, these changes were not observed in PCP-treated rats or in saline-treated rats receiving URB597. In the dorsomedial part of the bed nucleus of the stria terminalis (dmBNST), SI-induced c-Fos expression was observed only in PCP-treated rats. Interestingly, URB597 in PCP-treated rats restored a similar c-Fos expression pattern as observed in saline-treated rats: activation of the orbitofrontal cortex, inhibition of the central amygdala and suppression of activation of the dmBNST. These data suggest that orbitofrontal cortex, central amygdala and dmBNST play a critical role in the reversal of PCP-induced social withdrawal by URB597. Copyright © 2016 Elsevier Ireland Ltd and Japan Neuroscience Society. All rights reserved.

A high-resolution stochastic model of domestic activity patterns and electricity demand

International Nuclear Information System (INIS)

Widen, Joakim; Waeckelgard, Ewa

2010-01-01

Realistic time-resolved data on occupant behaviour, presence and energy use are important inputs to various types of simulations, including performance of small-scale energy systems and buildings' indoor climate, use of lighting and energy demand. This paper presents a modelling framework for stochastic generation of high-resolution series of such data. The model generates both synthetic activity sequences of individual household members, including occupancy states, and domestic electricity demand based on these patterns. The activity-generating model, based on non-homogeneous Markov chains that are tuned to an extensive empirical time-use data set, creates a realistic spread of activities over time, down to a 1-min resolution. A detailed validation against measurements shows that modelled power demand data for individual households as well as aggregate demand for an arbitrary number of households are highly realistic in terms of end-use composition, annual and diurnal variations, diversity between households, short time-scale fluctuations and load coincidence. An important aim with the model development has been to maintain a sound balance between complexity and output quality. Although the model yields a high-quality output, the proposed model structure is uncomplicated in comparison to other available domestic load models.

Evaluating auditory perception and communication demands required to carry out work tasks and complimentary hearing resources and skills for older workers with hearing loss.

Science.gov (United States)

Jennings, M B; Shaw, L; Hodgins, H; Kuchar, D A; Bataghva, L Poost-Foroosh

2010-01-01

For older workers with acquired hearing loss, this loss as well as the changing nature of work and the workforce, may lead to difficulties and disadvantages in obtaining and maintaining employment. Currently there are very few instruments that can assist workplaces, employers and workers to prepare for older workers with hearing loss or with the evaluation of auditory perception demands of work, especially those relevant to communication, and safety sensitive workplaces that require high levels of communication. This paper introduces key theoretical considerations that informed the development of a new framework, The Audiologic Ergonomic (AE) Framework to guide audiologists, work rehabilitation professionals and workers in developing tools to support the identification and evaluation of auditory perception demands in the workplace, the challenges to communication and the subsequent productivity and safety in the performance of work duties by older workers with hearing loss. The theoretical concepts underpinning this framework are discussed along with next steps in developing tools such as the Canadian Hearing Demands Tool (C-HearD Tool) in advancing approaches to evaluate auditory perception and communication demands in the workplace.

Global modeling of withdrawal, allocation and consumptive use of surface water and groundwater resources

NARCIS (Netherlands)

Wada, Y.; Wisser, D.; Bierkens, M. F. P.

2014-01-01

To sustain growing food demand and increasing standard of living, global water withdrawal and consumptive water use have been increasing rapidly. To analyze the human perturbation on water resources consistently over large scales, a number of macro-scale hydrological models (MHMs) have been

Building the evidence on simulation validity: comparison of anesthesiologists' communication patterns in real and simulated cases.

Science.gov (United States)

Weller, Jennifer; Henderson, Robert; Webster, Craig S; Shulruf, Boaz; Torrie, Jane; Davies, Elaine; Henderson, Kaylene; Frampton, Chris; Merry, Alan F

2014-01-01

Effective teamwork is important for patient safety, and verbal communication underpins many dimensions of teamwork. The validity of the simulated environment would be supported if it elicited similar verbal communications to the real setting. The authors hypothesized that anesthesiologists would exhibit similar verbal communication patterns in routine operating room (OR) cases and routine simulated cases. The authors further hypothesized that anesthesiologists would exhibit different communication patterns in routine cases (real or simulated) and simulated cases involving a crisis. Key communications relevant to teamwork were coded from video recordings of anesthesiologists in the OR, routine simulation and crisis simulation and percentages were compared. The authors recorded comparable videos of 20 anesthesiologists in the two simulations, and 17 of these anesthesiologists in the OR, generating 400 coded events in the OR, 683 in the routine simulation, and 1,419 in the crisis simulation. The authors found no significant differences in communication patterns in the OR and the routine simulations. The authors did find significant differences in communication patterns between the crisis simulation and both the OR and the routine simulations. Participants rated team communication as realistic and considered their communications occurred with a similar frequency in the simulations as in comparable cases in the OR. The similarity of teamwork-related communications elicited from anesthesiologists in simulated cases and the real setting lends support for the ecological validity of the simulation environment and its value in teamwork training. Different communication patterns and frequencies under the challenge of a crisis support the use of simulation to assess crisis management skills.

Optimizing withdrawal from drinking water reservoirs to reduce downstream temperature pollution and reservoir hypoxia.

Science.gov (United States)

Weber, M; Rinke, K; Hipsey, M R; Boehrer, B

2017-07-15

Sustainable management of drinking water reservoirs requires balancing the demands of water supply whilst minimizing environmental impact. This study numerically simulates the effect of an improved withdrawal scheme designed to alleviate the temperature pollution downstream of a reservoir. The aim was to identify an optimal withdrawal strategy such that water of a desirable discharge temperature can be supplied downstream without leading to unacceptably low oxygen concentrations within the reservoir. First, we calibrated a one-dimensional numerical model for hydrodynamics and oxygen dynamics (GLM-AED2), verifying that the model reproduced water temperatures and hypolimnetic dissolved oxygen concentrations accurately over a 5 year period. Second, the model was extended to include an adaptive withdrawal functionality, allowing for a prescribed withdrawal temperature to be found, with the potential constraint of hypolimnetic oxygen concentration. Scenario simulations on epi-/metalimnetic withdrawal demonstrate that the model is able to autonomously determine the best withdrawal height depending on the thermal structure and the hypolimnetic oxygen concentration thereby optimizing the ability to supply a desirable discharge temperature to the downstream river during summer. This new withdrawal strategy also increased the hypolimnetic raw water volume to be used for drinking water supply, but reduced the dissolved oxygen concentrations in the deep and cold water layers (hypolimnion). Implications of the results for reservoir management are discussed and the numerical model is provided for operators as a simple and efficient tool for optimizing the withdrawal strategy within different reservoir contexts. Copyright © 2017 Elsevier Ltd. All rights reserved.

Same organization, same electronic health records (EHRs) system, different use: exploring the linkage between practice member communication patterns and EHR use patterns in an ambulatory care setting

Science.gov (United States)

Leykum, Luci K; McDaniel, Reuben R

2011-01-01

Objective Despite efforts made by ambulatory care organizations to standardize the use of electronic health records (EHRs), practices often incorporate these systems into their work differently from each other. One potential factor contributing to these differences is within-practice communication patterns. The authors explore the linkage between within-practice communication patterns and practice-level EHR use patterns. Design Qualitative study of six practices operating within the same multi-specialty ambulatory care organization using the same EHR system. Semistructured interviews and direct observation were conducted with all physicians, nurses, medical assistants, practice managers, and non-clinical staff from each practice. Measurements An existing model of practice relationships was used to analyze communication patterns within the practices. Practice-level EHR use was defined and analyzed as the ways in which a practice uses an EHR as a collective or a group—including the degree of feature use, level of EHR-enabled communication, and frequency that EHR use changes in a practice. Interview and observation data were analyzed for themes. Based on these themes, within-practice communication patterns were categorized as fragmented or cohesive, and practice-level EHR use patterns were categorized as heterogeneous or homogeneous. Practices where EHR use was uniformly high across all users were further categorized as having standardized EHR use. Communication patterns and EHR use patterns were compared across the six practices. Results Within-practice communication patterns were associated with practice-level EHR use patterns. In practices where communication patterns were fragmented, EHR use was heterogeneous. In practices where communication patterns were cohesive, EHR use was homogeneous. Additional analysis revealed that practices that had achieved standardized EHR use (uniformly high EHR use across all users) exhibited high levels of mindfulness and

Same organization, same electronic health records (EHRs) system, different use: exploring the linkage between practice member communication patterns and EHR use patterns in an ambulatory care setting.

Science.gov (United States)

Lanham, Holly Jordan; Leykum, Luci K; McDaniel, Reuben R

2012-01-01

Despite efforts made by ambulatory care organizations to standardize the use of electronic health records (EHRs), practices often incorporate these systems into their work differently from each other. One potential factor contributing to these differences is within-practice communication patterns. The authors explore the linkage between within-practice communication patterns and practice-level EHR use patterns. Qualitative study of six practices operating within the same multi-specialty ambulatory care organization using the same EHR system. Semistructured interviews and direct observation were conducted with all physicians, nurses, medical assistants, practice managers, and non-clinical staff from each practice. An existing model of practice relationships was used to analyze communication patterns within the practices. Practice-level EHR use was defined and analyzed as the ways in which a practice uses an EHR as a collective or a group-including the degree of feature use, level of EHR-enabled communication, and frequency that EHR use changes in a practice. Interview and observation data were analyzed for themes. Based on these themes, within-practice communication patterns were categorized as fragmented or cohesive, and practice-level EHR use patterns were categorized as heterogeneous or homogeneous. Practices where EHR use was uniformly high across all users were further categorized as having standardized EHR use. Communication patterns and EHR use patterns were compared across the six practices. Within-practice communication patterns were associated with practice-level EHR use patterns. In practices where communication patterns were fragmented, EHR use was heterogeneous. In practices where communication patterns were cohesive, EHR use was homogeneous. Additional analysis revealed that practices that had achieved standardized EHR use (uniformly high EHR use across all users) exhibited high levels of mindfulness and respectful interaction, whereas practices that

Global modeling of withdrawal, allocation and consumptive use of surface water and groundwater resources

NARCIS (Netherlands)

Wada, Y.; Wisser, D.; Bierkens, M.F.P.

2013-01-01

To sustain growing food demand and increasing standard of living, global water withdrawal and consumptive water use have been increasing rapidly. To analyze the human perturbation on water resources consistently over a large scale, a number of macro-scale hydrological models (MHMs) have been

Emerging technologies for demand side management. Demand side management jitsugen no tame no saishin gijutsu

Energy Technology Data Exchange (ETDEWEB)

Suzuki, H; Iyoda, I [Mitsubishi Electric Corp., Tokyo (Japan)

1993-11-05

This paper explains the latest situation in hardware technologies to realize the demand side management, divided into the following technologies: communications technology, measurement technology, client information system technology, load controlling technology, home automation technology, and energy storing and saving technologies. Speaking of the communications technology, information exchange between the supply side and the demand side is important in the demand side management, whereas a technology intended of automatic power distribution and automatic meter-reading is advancing in development. The technology covers transmissions using from power lines and telephone lines to optical cables and wireless communications. Power line communications using power transmission lines as communication lines are simple and economical, but weak against noise, and not suitable for long-distance communications. Wireless communications have been drawing attentions along with the development of mobile communication device technologies. These technologies will give benefits to electric power companies in the initial stage of their use, such as for load investigation and general automation in power distribution. They would shift to benefiting users in about 2010 covering from security information such as about power interruption to publicity information and educations. 8 refs., 8 figs., 1 tab.

Patient-provider communication and low-income adults: age, race, literacy, and optimism predict communication satisfaction.

Science.gov (United States)

Jensen, Jakob D; King, Andy J; Guntzviller, Lisa M; Davis, LaShara A

2010-04-01

To assess whether literacy, numeracy, and optimism are related to low-income adults' satisfaction with their healthcare provider's communication skills. Low-income adults (N=131) were recruited from seven counties in Indiana through University extension programs. To achieve research triangulation, participants were surveyed and interviewed about their communication satisfaction with health providers. Survey data revealed that four variables significantly predicted satisfaction: age, race, literacy, and optimism. Low-income adults in the current study were more critical of their healthcare provider's communication skills if they were younger, White, functionally literate, and pessimistic. Follow-up interviews confirmed this pattern and suggested it was a byproduct of patient activism. In low-income populations, communication satisfaction may be lower for groups that are traditionally active in doctor-patient interactions (e.g., younger patients, patients with higher literacy skills). Healthcare providers should be aware that older, non-White, optimistic, and literacy deficient patients report greater communication satisfaction than their younger, White, pessimistic, and functionally literate peers. Both groups may be coping with their situation, the former by withdrawing and the latter by actively pushing for a higher standard of care. Healthcare providers should continue to seek out ways to facilitate dialogue with these underserved groups. 2009 Elsevier Ireland Ltd. All rights reserved.

The environmental cost of a reference withdrawal from surface waters: Definition and geography

Science.gov (United States)

Soligno, Irene; Ridolfi, Luca; Laio, Francesco

2017-12-01

World freshwater ecosystems are significantly deteriorating at a faster rate than other ecosystems. Water withdrawals are recognized as one of the main drivers of growing water stress in river basins worldwide. Over the years, much effort has been devoted to quantify water withdrawals at a global scale; however, comparisons are not simple because the uneven spatiotemporal distribution of surface water resources entails that the same amount of consumed water does not have the same environmental cost in different times or places. In order to account for this spatiotemporal heterogeneity, this work proposes a novel index to assess the environmental cost of a withdrawal from a generic river section. The index depends on (i) the environmental relevance of the impacted fluvial ecosystem (e.g., bed-load transport capacity, width of the riparian belt, biodiversity richness) and (ii) the downstream river network affected by the water withdrawal. The environmental cost has been estimated in each and every river section worldwide considering a reference withdrawal. Being referred to a unitary reference withdrawal that can occur in any river section worldwide, our results can be suitably arranged for describing any scenario of surface water consumption (i.e., as the superposition of the actual pattern of withdrawals). The index aims to support the interpretation of the volumetric measure of surface water withdrawal with a perspective that takes into account the fluvial system where the withdrawal actually occurs. The application of the index highlights the river regions where withdrawals can cause higher environmental costs, with the challenge of weighting each water withdrawal considering the responsibilities that it has on downstream freshwater ecosystems.

Calling patterns in human communication dynamics.

Science.gov (United States)

Jiang, Zhi-Qiang; Xie, Wen-Jie; Li, Ming-Xia; Podobnik, Boris; Zhou, Wei-Xing; Stanley, H Eugene

2013-01-29

Modern technologies not only provide a variety of communication modes (e.g., texting, cell phone conversation, and online instant messaging), but also detailed electronic traces of these communications between individuals. These electronic traces indicate that the interactions occur in temporal bursts. Here, we study intercall duration of communications of the 100,000 most active cell phone users of a Chinese mobile phone operator. We confirm that the intercall durations follow a power-law distribution with an exponential cutoff at the population level but find differences when focusing on individual users. We apply statistical tests at the individual level and find that the intercall durations follow a power-law distribution for only 3,460 individuals (3.46%). The intercall durations for the majority (73.34%) follow a Weibull distribution. We quantify individual users using three measures: out-degree, percentage of outgoing calls, and communication diversity. We find that the cell phone users with a power-law duration distribution fall into three anomalous clusters: robot-based callers, telecom fraud, and telephone sales. This information is of interest to both academics and practitioners, mobile telecom operators in particular. In contrast, the individual users with a Weibull duration distribution form the fourth cluster of ordinary cell phone users. We also discover more information about the calling patterns of these four clusters (e.g., the probability that a user will call the c(r)-th most contact and the probability distribution of burst sizes). Our findings may enable a more detailed analysis of the huge body of data contained in the logs of massive users.

Dynamic temperature dependence patterns in future energy demand models in the context of climate change

International Nuclear Information System (INIS)

Hekkenberg, M.; Moll, H.C.; Uiterkamp, A.J.M. Schoot

2009-01-01

Energy demand depends on outdoor temperature in a 'u' shaped fashion. Various studies have used this temperature dependence to investigate the effects of climate change on energy demand. Such studies contain implicit or explicit assumptions to describe expected socio-economic changes that may affect future energy demand. This paper critically analyzes these implicit or explicit assumptions and their possible effect on the studies' outcomes. First we analyze the interaction between the socio-economic structure and the temperature dependence pattern (TDP) of energy demand. We find that socio-economic changes may alter the TDP in various ways. Next we investigate how current studies manage these dynamics in socio-economic structure. We find that many studies systematically misrepresent the possible effect of socio-economic changes on the TDP of energy demand. Finally, we assess the consequences of these misrepresentations in an energy demand model based on temperature dependence and climate scenarios. Our model results indicate that expected socio-economic dynamics generally lead to an underestimation of future energy demand in models that misrepresent such dynamics. We conclude that future energy demand models should improve the incorporation of socio-economic dynamics. We propose dynamically modeling several key parameters and using direct meteorological data instead of degree days. (author)

Buprenorphine for managing opioid withdrawal.

Science.gov (United States)

Gowing, Linda; Ali, Robert; White, Jason M; Mbewe, Dalitso

2017-02-21

outcome. Buprenorphine is more effective than clonidine or lofexidine for managing opioid withdrawal in terms of severity of withdrawal, duration of withdrawal treatment, and the likelihood of treatment completion.Buprenorphine and methadone appear to be equally effective, but data are limited. It remains possible that the pattern of withdrawal experienced may differ and that withdrawal symptoms may resolve more quickly with buprenorphine.It is not possible to draw any conclusions from the available evidence on the relative effectiveness of different rates of tapering the buprenorphine dose. The divergent findings of studies included in this review suggest that there may be multiple factors affecting the response to the rate of dose taper. One such factor could be whether or not the initial treatment plan includes a transition to subsequent relapse prevention treatment with naltrexone. Indeed, the use of buprenorphine to support transition to naltrexone treatment is an aspect worthy of further research.Most participants in the studies included in this review were male. None of the studies reported outcomes on the basis of sex, preventing any exploration of differences related to this variable. Consideration of sex as a factor influencing response to withdrawal treatment would be relevant research for selecting the most appropriate type of intervention for each individual.

Worldwide withdrawal of medicinal products because of adverse drug reactions: a systematic review and analysis.

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Onakpoya, Igho J; Heneghan, Carl J; Aronson, Jeffrey K

2016-07-01

We have systematically identified medicinal products withdrawn worldwide because of adverse drug reactions, assessed the level of evidence used for making the withdrawal decisions, and explored the patterns of withdrawals over time. We searched PubMed, the WHO database of withdrawn products, and selected texts. We included products that were withdrawn after launch from 1950 onwards, excluding non-human and over-the-counter medicines. We assessed the levels of evidence on which withdrawals were based using the Oxford Center for Evidence Based Medicine Levels of Evidence. Of 353 medicinal products withdrawn from any country, only 40 were withdrawn worldwide. Anecdotal reports were cited as evidence for withdrawal in 30 (75%) and deaths occurred in 27 (68%). Hepatic, cardiac, and nervous system toxicity accounted for over 60% of withdrawals. In 28 cases, the first withdrawal was initiated by the manufacturer. The median interval between the first report of an adverse drug reaction that led to withdrawal and the first withdrawal was 1 year (range 0-43 years). Worldwide withdrawals occurred within 1 year after the first withdrawal in any country. In conclusion, the time it takes for drugs to be withdrawn worldwide after reports of adverse drug reactions has shortened over time. However, there are inconsistencies in current withdrawal procedures when adverse drug reactions are suspected. A uniform method for establishing worldwide withdrawal of approved medicinal products when adverse drug reactions are suspected should be developed, to facilitate global withdrawals. Rapid synthesis of the evidence on harms should be a priority when serious adverse reactions are suspected.

Trajectories of Social Withdrawal from Grades 1 to 6: Prediction from Early Parenting, Attachment, and Temperament

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Booth-LaForce, Cathryn; Oxford, Monica L.

2008-01-01

From 1,092 children in the NICHD Study of Early Child Care and Youth Development, the authors identified 3 trajectory patterns of social withdrawal from teacher reports in Grades 1-6: a normative consistently low group (86%), a decreasing group (5%) with initially high withdrawal that decreased, and an increasing group (9%) with initially low…

Internationalization Patterns of Small High Technology Firms: Keep On, Step Back, or Withdraw

DEFF Research Database (Denmark)

Turcan, Romeo V.; Jones, Marian

activity or withdrawal from international engagement. Future research questions and recommendations to policy makers are provided. As the research findings provide support for an emerging concept of a cyclical mode of internationalisation, the authors suggest furthering the research on the cyclical mode...

Attention biases to threat and behavioral inhibition in early childhood shape adolescent social withdrawal.

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Pérez-Edgar, Koraly; Bar-Haim, Yair; McDermott, Jennifer Martin; Chronis-Tuscano, Andrea; Pine, Daniel S; Fox, Nathan A

2010-06-01

Behavioral inhibition (BI) is a temperament characterized in young children by a heightened sensitivity to novelty, social withdrawal, and anxious behaviors. For many children, these social difficulties dissipate over time. For others, patterns of social withdrawal continue into adolescence. Over time, attention biases to threat may influence the stability of BI and its association with social withdrawal, ultimately modulating the risk for anxiety disorders in BI children. However, we know relatively little about the cognitive processes that accompany BI and shape later socio-emotional functioning. We examined the relations among BI in childhood, attention biases to threat in adolescence, and adolescent social withdrawal in a longitudinal study (N = 126, Mean age = 15 years). As has been reported in anxious adults, adolescents who were behaviorally inhibited as toddlers and young children showed heightened attention bias to threat. In addition, attention bias to threat moderated the relation between childhood BI and adolescent social withdrawal.

Predictive factors of mother-child communication patterns in the mothers referred to Khorramabad Shahid Madani hospital in 2012

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khatereh Anbari

2014-03-01

Full Text Available Background : The quality of mother-child relationship play an important role in personality shaping, social functioning and mental health of children in the future . This study was designed to evaluate the prognostic factors of mother - child relationship patterns.   Materials and Methods: In this cross sectional study 110 mothers admitted to children's hospital of Khorramabad selected by consecutive sampling method. Data gathering tool was Mother - Child Relationship Evaluation (MCRE questionnaire. At first the view points of the mothers about four communication patterns including: over protection, child rejection, overneglignce and child acceptance were examined, then according to each pattern cut off, the type of communication pattern was determined. Fisher's exact test and linear regression were used for data analysis.   Results: The mean age of participants was 28.6±6.46. Communication pattern in 66.4% of the mothers was over protection and 19.1% of them had overneglence pattern. Also communication pattern in 12.8% of the participants was child acceptance and 1.8% followed from child rejectoin communication pattern. A significant statistical relation was seen between age, education level, marital status, mothers residence and pregnancy status with the pattern of their relationship (P <0.05. In linear regression analysis, most important factors in predicting the communication pattern were single parent and unplanned pregnancy.   Conclusion: Raising awareness of mothers through workshops can increase proper child skills and led to the development of social skills and reducing child behavior problems in the future.

Extracting Association Patterns in Network Communications

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Portela, Javier; Villalba, Luis Javier García; Trujillo, Alejandra Guadalupe Silva; Orozco, Ana Lucila Sandoval; Kim, Tai-hoon

2015-01-01

In network communications, mixes provide protection against observers hiding the appearance of messages, patterns, length and links between senders and receivers. Statistical disclosure attacks aim to reveal the identity of senders and receivers in a communication network setting when it is protected by standard techniques based on mixes. This work aims to develop a global statistical disclosure attack to detect relationships between users. The only information used by the attacker is the number of messages sent and received by each user for each round, the batch of messages grouped by the anonymity system. A new modeling framework based on contingency tables is used. The assumptions are more flexible than those used in the literature, allowing to apply the method to multiple situations automatically, such as email data or social networks data. A classification scheme based on combinatoric solutions of the space of rounds retrieved is developed. Solutions about relationships between users are provided for all pairs of users simultaneously, since the dependence of the data retrieved needs to be addressed in a global sense. PMID:25679311

Extracting Association Patterns in Network Communications

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Javier Portela

2015-02-01

Full Text Available In network communications, mixes provide protection against observers hiding the appearance of messages, patterns, length and links between senders and receivers. Statistical disclosure attacks aim to reveal the identity of senders and receivers in a communication network setting when it is protected by standard techniques based on mixes. This work aims to develop a global statistical disclosure attack to detect relationships between users. The only information used by the attacker is the number of messages sent and received by each user for each round, the batch of messages grouped by the anonymity system. A new modeling framework based on contingency tables is used. The assumptions are more flexible than those used in the literature, allowing to apply the method to multiple situations automatically, such as email data or social networks data. A classification scheme based on combinatoric solutions of the space of rounds retrieved is developed. Solutions about relationships between users are provided for all pairs of users simultaneously, since the dependence of the data retrieved needs to be addressed in a global sense.

Neonatal opioid withdrawal syndrome.

Science.gov (United States)

Sutter, Mary Beth; Leeman, Lawrence; Hsi, Andrew

2014-06-01

Neonatal opioid withdrawal syndrome is common due to the current opioid addiction epidemic. Infants born to women covertly abusing prescription opioids may not be identified as at risk until withdrawal signs present. Buprenorphine is a newer treatment for maternal opioid addiction and appears to result in a milder withdrawal syndrome than methadone. Initial treatment is with nonpharmacological measures including decreasing stimuli, however pharmacological treatment is commonly required. Opioid monotherapy is preferred, with phenobarbital or clonidine uncommonly needed as adjunctive therapy. Rooming-in and breastfeeding may decease the severity of withdrawal. Limited evidence is available regarding long-term effects of perinatal opioid exposure. Copyright © 2014 Elsevier Inc. All rights reserved.

Machine Learning for Identifying Demand Patterns of Home Energy Management Systems with Dynamic Electricity Pricing

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Derck Koolen

2017-11-01

Full Text Available Energy management plays a crucial role in providing necessary system flexibility to deal with the ongoing integration of volatile and intermittent energy sources. Demand Response (DR programs enhance demand flexibility by communicating energy market price volatility to the end-consumer. In such environments, home energy management systems assist the use of flexible end-appliances, based upon the individual consumer’s personal preferences and beliefs. However, with the latter heterogeneously distributed, not all dynamic pricing schemes are equally adequate for the individual needs of households. We conduct one of the first large scale natural experiments, with multiple dynamic pricing schemes for end consumers, allowing us to analyze different demand behavior in relation with household attributes. We apply a spectral relaxation clustering approach to show distinct groups of households within the two most used dynamic pricing schemes: Time-Of-Use and Real-Time Pricing. The results indicate that a more effective design of smart home energy management systems can lead to a better fit between customer and electricity tariff in order to reduce costs, enhance predictability and stability of load and allow for more optimal use of demand flexibility by such systems.

Control rod withdrawal monitoring device

International Nuclear Information System (INIS)

Ebisuya, Mitsuo.

1984-01-01

Purpose: To prevent the power ramp even if a plurality of control rods are subjected to withdrawal operation at a time, by reducing the reactivity applied to the reactor. Constitution: The control rod withdrawal monitoring device is adapted to monitor and control the withdrawal of the control rods depending on the reactor power and the monitoring region thereof is divided into a control rod group monitoring region a transition region and a control group monitoring not interfere region. In a case if the distance between a plurality of control rods for which the withdrawal positions are selected is less than a limiting value, the coordinate for the control rods, distance between the control rods and that the control rod distance is shorter are displayed on a display panel, and the withdrawal for the control rods are blocked. Accordingly, even if a plurality of control rods are subjected successively to the withdrawal operation contrary to the control rod withdrawal sequence upon high power operation of the reactor, the power ramp can be prevented. (Kawakami, Y.)

Behavioral and Single-Neuron Sensitivity to Millisecond Variations in Temporally Patterned Communication Signals.

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Baker, Christa A; Ma, Lisa; Casareale, Chelsea R; Carlson, Bruce A

2016-08-24

In many sensory pathways, central neurons serve as temporal filters for timing patterns in communication signals. However, how a population of neurons with diverse temporal filtering properties codes for natural variation in communication signals is unknown. Here we addressed this question in the weakly electric fish Brienomyrus brachyistius, which varies the time intervals between successive electric organ discharges to communicate. These fish produce an individually stereotyped signal called a scallop, which consists of a distinctive temporal pattern of ∼8-12 electric pulses. We manipulated the temporal structure of natural scallops during behavioral playback and in vivo electrophysiology experiments to probe the temporal sensitivity of scallop encoding and recognition. We found that presenting time-reversed, randomized, or jittered scallops increased behavioral response thresholds, demonstrating that fish's electric signaling behavior was sensitive to the precise temporal structure of scallops. Next, using in vivo intracellular recordings and discriminant function analysis, we found that the responses of interval-selective midbrain neurons were also sensitive to the precise temporal structure of scallops. Subthreshold changes in membrane potential recorded from single neurons discriminated natural scallops from time-reversed, randomized, and jittered sequences. Pooling the responses of multiple neurons improved the discriminability of natural sequences from temporally manipulated sequences. Finally, we found that single-neuron responses were sensitive to interindividual variation in scallop sequences, raising the question of whether fish may analyze scallop structure to gain information about the sender. Collectively, these results demonstrate that a population of interval-selective neurons can encode behaviorally relevant temporal patterns with millisecond precision. The timing patterns of action potentials, or spikes, play important roles in representing

An Emerging New Paradigm in Opioid Withdrawal: A Critical Role for Glia-Neuron Signaling in the Periaqueductal Gray

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Handong Ouyang

2012-01-01

Full Text Available The chronic use of opiates (i.e., narcotics such as the natural derivatives of opium including morphine or codeine or opioids (i.e., semisynthetic derivatives of opium and other molecules that activate opioid receptors induces dependence, which is associated with various specific behavioral and somatic signs after their withdrawal or after the administration of an opioid antagonist. Among the brain regions implicated in opiate dependence and withdrawal, the periaqueductal gray area (PAG appears to be critical in regulating the complex signs and symptoms of opioid withdrawal. Numerous neurochemical mechanisms in the PAG have been identified that may contribute to the opioid withdrawal syndrome. Accumulating evidence suggests that glial activation leading to the release of proinflammatory molecules acting on neurons is important in the complex syndrome of opioid dependence and withdrawal. This paper focuses on the recent advances in our understanding of the vital role that glia-neuron interactions play in opioid dependence and withdrawal within the PAG. We summarize those neurochemical mechanisms associated with opioid withdrawal including the recently defined importance of TNFα release from activated glial cells that communicate with TNF receptors on PAG neurons.

Time to Death after Terminal Withdrawal of Mechanical Ventilation: Specific Respiratory and Physiologic Parameters May Inform Physician Predictions.

Science.gov (United States)

Long, Ann C; Muni, Sarah; Treece, Patsy D; Engelberg, Ruth A; Nielsen, Elizabeth L; Fitzpatrick, Annette L; Curtis, J Randall

2015-12-01

Discussions about withdrawal of life-sustaining therapies often include family members of critically ill patients. These conversations should address essential components of the dying process, including expected time to death after withdrawal. The study objective was to aid physician communication about the dying process by identifying predictors of time to death after terminal withdrawal of mechanical ventilation. We conducted an observational analysis from a single-center, before-after evaluation of an intervention to improve palliative care. We studied 330 patients who died after terminal withdrawal of mechanical ventilation. Predictors included patient demographics, laboratory, respiratory, and physiologic variables, and medication use. The median time to death for the entire cohort was 0.58 hours (interquartile range (IQR) 0.22-2.25 hours) after withdrawal of mechanical ventilation. Using Cox regression, independent predictors of shorter time to death included higher positive end-expiratory pressure (per 1 cm H2O hazard ratio [HR], 1.07; 95% CI 1.04-1.11); higher static pressure (per 1 cm H2O HR, 1.03; 95% CI 1.01-1.04); extubation prior to death (HR, 1.41; 95% CI 1.06-1.86); and presence of diabetes (HR, 1.75; 95% CI 1.25-2.44). Higher noninvasive mean arterial pressure predicted longer time to death (per 1 mmHg HR, 0.98; 95% CI 0.97-0.99). Comorbid illness and key respiratory and physiologic parameters may inform physician predictions of time to death after withdrawal of mechanical ventilation. An understanding of the predictors of time to death may facilitate discussions with family members of dying patients and improve communication about end-of-life care.

Optimization of ground-water withdrawal in the lower Fox River communities, Wisconsin

Science.gov (United States)

Walker, J.F.; Saad, D.A.; Krohelski, J.T.

1998-01-01

Pumping from closely spaced wells in the Central Brown County area and the Fox Cities area near the north shore of Lake Winnebago has resulted in the formation of deep cones of depression in the vicinity of the two pumping centers. Water-level measurements indicate there has been a steady decline in water levels in the vicinity of these two pumping centers for the past 50 years. This report describes the use of ground-water optimization modeling to efficiently allocate the ground-water resources in the Lower Fox River Valley. A 3-dimensional ground-water flow model was used along with optimization techniques to determine the optimal withdrawal rates for a variety of management alternatives. The simulations were conducted separately for the Central Brown County area and the Fox Cities area. For all simulations, the objective of the optimization was to maximize total ground-water withdrawals. The results indicate that ground water can supply nearly all of the projected 2030 demand for Central Brown County municipalities if all of the wells are managed (including the city of Green Bay), 8 new wells are installed, and the water-levels are allowed to decline to 100 ft below the bottom of the confining unit. Ground water can supply nearly all of the projected 2030 demand for the Fox Cities if the municipalities in Central Brown County convert to surface water; if Central Brown County municipalities follow the optimized strategy described above, there will be a considerable shortfall of available ground water for the Fox Cities communities. Relaxing the water-level constraint in a few wells, however, would likely result in increased availability of water. In all cases examined, optimization alternatives result in a rebound of the steady-state water levels due to projected 2030 withdrawal rates to levels at or near the bottom of the confining unit, resulting in increased well capacity. Because the simulations are steady-state, if all of the conditions of the model remain

A study on the operator's communication pattern characteristics under abnormal operating situation of nuclear power plants

International Nuclear Information System (INIS)

Kim, S. H.; Park, J.

2008-01-01

The quality of a probabilistic safety assessment (PSA) has become more important and a human reliability analysis (HRA) is known as a major contributor to the uncertainty of a PSA. As a part of enhancing the HRA quality, a study was initiated to find out characteristics of communication pattern and to evaluate communication quality of the operators of nuclear power plants. Korea Atomic Energy Research Institute (KAERI) is developing evaluation methods for the effect of human-induced events on risk/performance. This paper describes a study on the operator's communication pattern characteristics under abnormal operating situation of nuclear power plants. The study was carried out in four stages; 1) Video recording 2) Audio scripting 3) Message Classification 4) Communication Pattern Analysis. We recorded eight abnormal simulator training programs from Younggwang nuclear power plant training center. After that we performed message classification and carried out communication pattern analysis. We compared communication patterns of abnormal operating situation with emergency operating situation.As results of analysis, the role of SRO (senior reactor operator) under abnormal operating situation was decreased than the activities under emergency operating situation because each operator (reactor operator, turbine operator, safety supervisor) in main control room (MCR) performs the activity to control by himself with corresponding field engineers with his basic knowledge of the system. On the other hand, the operator's decision making processes and activities under abnormal operating situation were dramatically increased than the emergency operating situation. (authors)

CRISP. Market-oriented online supply-demand matching

International Nuclear Information System (INIS)

Kamphuis, I.G.; Kester, J.C.P.; Carlsson, P; Akkermans, H.

2004-04-01

Current power distribution systems are operated in a top-down manner. Power production control and price formation take place on a central level on the basis of relatively static data from a data collection and dispatching network with a limited scope and granularity. When incorporating a more considerable fraction of small-scale producers on the basis of, for instance, renewable energy, operation of the distribution grid requires more data to be collected from a more extensive information and data communication network. Furthermore, increased local flows, in the form of two-way communication with distributed computation techniques, enable a more dynamic adaptation in power supply and demand patterns paving the way to a flexible way of embedding of ill-predictable supply of some types of renewable energy sources. DSM-programs have been in use in the utility sector for years now. In this document, first, current Demand Side Management (DSM) and Demand Response Resource (DRR) techniques are discussed; then, supply side management especially in a DG (Distributed Generation) context is treated. A framework of novel concepts and possible technology directions is presented subsequently and some preliminary scenarios are shown to illustrate these concepts. An overview of more flexible supply and demand matching schemes is given essentially based on four distinct types of SDM clusters. It appears, that it is possible to fulfil requirements for these distributed environments in terms of needed information and communication technology, ICT, if these are paralleled with the expected future penetration of ever-smaller scale data-exchange networks at power customer sites. Agent technology using algorithms from micro-economic market theory offers a promising possibility for managing the complexity of price formation and supply demand matching in these fine-grained bottom-up control distribution networks. Implication of these technical developments in terms of market and business

Psychometric evaluation of the Dutch version of the Subjective Opiate Withdrawal Scale (SOWS).

Science.gov (United States)

Dijkstra, Boukje A G; Krabbe, Paul F M; Riezebos, Truus G M; van der Staak, Cees P F; De Jong, Cor A J

2007-01-01

To evaluate the psychometric properties of the Dutch version of the 16-item Subjective Opiate Withdrawal Scale (SOWS). The SOWS measures withdrawal symptoms at the time of assessment. The Dutch SOWS was repeatedly administered to a sample of 272 opioid-dependent inpatients of four addiction treatment centers during rapid detoxification with or without general anesthesia. Examination of the psychometric properties of the SOWS included exploratory factor analysis, internal consistency, test-retest reliability, and criterion validity. Exploratory factor analysis of the SOWS revealed a general pattern of four factors with three items not always clustered in the same factors at different points of measurement. After excluding these items from factor analysis four factors were identified during detoxification (temperature dysregulation, tractus locomotorius, tractus gastro-intestinalis and facial disinhibition). The 13-item SOWS shows high internal consistency and test-retest reliability and good validity at different stages of withdrawal. The 13-item SOWS is a reliable and valid instrument to assess opioid withdrawal during rapid detoxification. Three items were deleted because their content does not correspond directly with opioid withdrawal symptoms. Copyright (c) 2007 S. Karger AG, Basel.

Smart Buildings and Demand Response

Science.gov (United States)

Kiliccote, Sila; Piette, Mary Ann; Ghatikar, Girish

2011-11-01

Advances in communications and control technology, the strengthening of the Internet, and the growing appreciation of the urgency to reduce demand side energy use are motivating the development of improvements in both energy efficiency and demand response (DR) systems in buildings. This paper provides a framework linking continuous energy management and continuous communications for automated demand response (Auto-DR) in various times scales. We provide a set of concepts for monitoring and controls linked to standards and procedures such as Open Automation Demand Response Communication Standards (OpenADR). Basic building energy science and control issues in this approach begin with key building components, systems, end-uses and whole building energy performance metrics. The paper presents a framework about when energy is used, levels of services by energy using systems, granularity of control, and speed of telemetry. DR, when defined as a discrete event, requires a different set of building service levels than daily operations. We provide examples of lessons from DR case studies and links to energy efficiency.

Approach and withdrawal motivation in schizophrenia: an examination of frontal brain asymmetric activity.

Science.gov (United States)

Horan, William P; Wynn, Jonathan K; Mathis, Ian; Miller, Gregory A; Green, Michael F

2014-01-01

Although motivational disturbances are common in schizophrenia, their neurophysiological and psychological basis is poorly understood. This electroencephalography (EEG) study examined the well-established motivational direction model of asymmetric frontal brain activity in schizophrenia. According to this model, relative left frontal activity in the resting EEG reflects enhanced approach motivation tendencies, whereas relative right frontal activity reflects enhanced withdrawal motivation tendencies. Twenty-five schizophrenia outpatients and 25 healthy controls completed resting EEG assessments of frontal asymmetry in the alpha frequency band (8-12 Hz), as well as a self-report measure of behavioral activation and inhibition system (BIS/BAS) sensitivity. Patients showed an atypical pattern of differences from controls. On the EEG measure patients failed to show the left lateralized activity that was present in controls, suggesting diminished approach motivation. On the self-report measure, patients reported higher BIS sensitivity than controls, which is typically interpreted as heightened withdrawal motivation. EEG asymmetry scores did not significantly correlate with BIS/BAS scores or with clinical symptom ratings among patients. The overall pattern suggests a motivational disturbance in schizophrenia characterized by elements of both diminished approach and elevated withdrawal tendencies.

Anticonvulsants for the treatment of alcohol withdrawal syndrome and alcohol use disorders.

Science.gov (United States)

Hammond, Christopher J; Niciu, Mark J; Drew, Shannon; Arias, Albert J

2015-04-01

Alcoholic patients suffer from harmful allostatic neuroplastic changes in the brain causing an acute withdrawal syndrome upon cessation of drinking followed by a protracted abstinence syndrome and an increased risk of relapse to heavy drinking. Benzodiazepines have long been the treatment of choice for detoxifying patients and managing alcohol withdrawal syndrome (AWS). Non-benzodiazepine anticonvulsants (NBACs) are increasingly being used both for alcohol withdrawal management and for ongoing outpatient treatment of alcohol dependence, with the goal of either abstinence or harm reduction. This expert narrative review summarizes the scientific basis and clinical evidence supporting the use of NBACs in treating AWS and for reducing harmful drinking patterns. There is less evidence in support of NBAC therapy for AWS, with few placebo-controlled trials. Carbamazepine and gabapentin appear to be the most promising adjunctive treatments for AWS, and they may be useful as monotherapy in select cases, especially in outpatient settings and for the treatment of mild-to-moderate low-risk patients with the AWS. The body of evidence supporting the use of the NBACs for reducing harmful drinking in the outpatient setting is stronger. Topiramate appears to have a robust effect on reducing harmful drinking in alcoholics. Gabapentin is a potentially efficacious treatment for reducing the risk of relapse to harmful drinking patterns in outpatient management of alcoholism. Gabapentin's ease of use, rapid titration, good tolerability, and efficacy in both the withdrawal and chronic phases of treatment make it particularly appealing. In summary, several NBACs appear to be beneficial in treating AWS and alcohol use disorders.

Short communication: Determination of withdrawal time for oxytetracycline in different types of goats for milk consumption.

Science.gov (United States)

Attaie, Rahmat; Bsharat, Mohammed; Mora-Gutierrez, Adela; Woldesenbet, Sela

2015-07-01

Antibiotics are widely used in animal husbandry and the presence of antibiotics in milk is a health hazard. The objective of this study was to determine residual amounts of oxytetracycline in fresh, aged, and pasteurized milk of 3 breeds of goats using HPLC analysis. It was also essential to determine the safe withdrawal period of oxytetracycline in lactating goats. The quantitative results obtained using the HPLC system were compared with the tolerance limit of oxytetracycline in milk in the United States. Fifteen milking does, 5 Nubians, 5 Alpines, and 5 LaManchas were randomly selected from the milking herd at the International Goat Research Center at Prairie View A&M University. A simple sample preparation and isocratic HPLC method using ultraviolet detection was used for analysis of milk samples. The HPLC results indicated that the withdrawal period of oxytetracycline in treated Alpine does was 82h (7 milking), whereas for Nubian does the period was 58h (5 milking), and for LaManchas the period was 72h (6 milking) after drug administration. The overall withdrawal period for all the treated goats of 3 breeds was 72h. Although these results indicated that the depletion rate of this antibiotic was faster in goats than the reported data for cows, the 96-h withdrawal period that is currently used for lactating cows is still necessary for these 3 breeds of goats. Additionally, our results indicated that oxytetracycline is not stable in goat milk at refrigeration temperature or during pasteurization and will decrease significantly. Copyright © 2015 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

An Examination of Strategic Philanthropy and CSR Communication Patterns among the World’s Twenty-One Largest Oil Companies

Directory of Open Access Journals (Sweden)

J. Brad Gatlin

2013-07-01

Full Text Available Fortune Magazine’s 2012 list of 100 largest companies included 21 oil companies. This paper seeks to discern patterns of those 21 companies’ philanthropic efforts and communication thereof. Specifically, the paper will consider issues such as ownership (all companies were either publicly-traded or state-owned, the economic development of the home country, and the citizens’ expectations of corporate citizens. The philanthropic efforts of all 21 companies are discussed in the context of Porter and Kramer’s (2001 framework of the competitive context It is concluded that the oil industry is particularly well-suited to affect factor and, to a lesser extent, demand conditions, through philanthropic efforts. A model for classifying the philanthropic based on ownership and country conditions is proposed, and suggestions for further research are made.

Peri-operative communication patterns and media usage--implications for systems design.

Science.gov (United States)

Karlsen, Ero S; Toussaint, Pieter Jelle

2010-01-01

Inter-hospital communication amounts for a great deal of clinicians' work time. While communication is essential to coordinate care, it can also be time consuming and interruptive, and breakdown in communication is an important source of medical errors. One contributor to the interruptive nature of communication is the use of synchronous media, and there is clearly a potential for novel technologies. To assess communication patterns and media usage we performed an ethnographic field study in the peri-operative environment at a Norwegian hospital, as well as interviews with nurses. We analyze the results with regards to choice of media, characteristics of the conversations taking place and meta-messages, and account for addressing, obtrusiveness and information richness in the message exchanges. We find a relative high degree of interruptiveness in communication, and ascribe it to 1) a lack of situational awareness between locations in the peri-operative domain, as well as 2) use of synchronous media. This suggests that design of novel technology for intra-hospital communication should aim at supporting sender-receiver awareness and signaling of availability.

Demand access communications for TDRSS users

Science.gov (United States)

Zillig, David; Weinberg, Aaron; Mcomber, Robert

1994-01-01

The Tracking and Data Relay Satellite System (TDRSS) has long been used to provide reliable low and high-data rate relay services between user spacecraft in Earth orbit and the ground. To date, these TDRSS services have been implemented via prior scheduling based upon estimates of user needs and mission event timelines. While this approach may be necessary for large users that require greater amounts of TDRSS resources, TDRSS can potentially offer the planned community of smaller science missions (e.g., the small explorer missions), and other emerging users, the unique opportunity for services on demand. In particular, innovative application of the existing TDRSS Multiple Access (MA) subsystem, with its phased array antenna, could be used to implement true demand access services without modification to either the TDRSS satellites or the user transponder, thereby introducing operational and performance benefits to both the user community and the Space Network. In this paper, candidate implementations of demand access service via the TDRSS MA subsystem are examined in detail. Both forward and return link services are addressed and a combination of qualitative and quantitative assessments are provided. The paper also identifies further areas for investigation in this ongoing activity that is being conducted by GSFC/Code 531 under the NASA Code O Advanced Systems Program.

Effect of intensive epilimnetic withdrawal on phytoplankton community in a (subtropical deep reservoir

Directory of Open Access Journals (Sweden)

Man Zhang

2013-10-01

Full Text Available Withdrawal is an important process in reservoir hydrodynamics, removing phytoplankton with flushed water. Zooplankton，the grazers of phytoplankton, having longer generation times, are even more susceptible than phytoplankton to flushing loss. Therefore phytoplankton are affected not only by abiotic conditions linked to hydrodynamics but also by zooplankton due to weakened grazing pressure. During the Asian Games (November 12-27, 2010 in Guangzhou, China, two intensive epilimnetic withdrawals were conducted in Liuxihe, a deep canyon-shaped reservoir. To examine the influence of the intensive epilimnetic withdrawals on the phytoplankton community, a seven-week field observation and a hydrodynamic simulation were carried out. The observation was divided in two stages: stage 1 represented partial surface vertical mixing period, and stage 2 represented intensive epilimnetic withdrawal period. It was found that phytoplankton abundance and biomass declined with water temperature and partial surface vertical mixing in stage 1. However, the intensive epilimnetic withdrawal reversed this decreasing trend and increased phytoplankton biomass and abundance in stage 2. Phytoplankton showed a higher rate of composition change in stage 2. A numerical model (DYRESM-CAEDYM simulated scenarios with and without epilimnetic withdrawal to test their effects on abiotic factors (water temperature, suspended sediment and soluble reactive phosphorus for phytoplankton. The results showed no obvious difference in the abiotic factors between the two scenarios during stage 2. We therefore suggested that the abiotic factors in the water column were probably driven by a seasonal pattern, not by epilimnetic withdrawal. It is likely that the intensive epilimnetic withdrawal could remove large crustaceans. The reduced grazing pressure probably explained the increase of phytoplankton biomass and abundance after the withdrawal. Thus, we suggest that reservoir operation should pay

Scientific communication in clinical psychology: examining patterns of citations and references.

Science.gov (United States)

Kiselica, Andrew M; Ruscio, John

2014-01-01

Previous studies of scientific communication used citation mapping, establishing psychology as a 'hub science' from which many other fields draw information. Within psychology, the clinical and counselling discipline is a major 'knowledge broker'. This study analyzed scientific communication among three major subdisciplines of clinical psychology-the cognitive-behavioural, psychodynamic and humanistic schools of thought-by examining patterns of references within and citations to 305 target articles published in leading journals of these subdisciplines. The results suggest that clinical researchers of each theoretical orientation engage in more insular scientific communication than an integrationist would find desirable and that cognitive-behavioural articles are more closely connected to mainstream psychology and related fields. Eclectic practitioners draw on several different theoretical orientations to inform their practice; as such, they should be interested in understanding the patterns of scientific communication within and across theoretical orientations. Practitioners work in a variety of different mental health settings, with a variety of other professionals in psychology-related fields, and should be interested in how much influence their particular theoretical orientation has on the work of colleagues. Many practitioners rely on new, evidence-based research to inform their work. The results of this study provide these individuals with an objective measure of the influence of empirical work in different areas of clinical psychology. Copyright © 2012 John Wiley & Sons, Ltd.

On the Mobile Communication Requirements for the Demand-Side Management of Electric Vehicles

Directory of Open Access Journals (Sweden)

Stefano Rinaldi

2018-05-01

Full Text Available The rising concerns about global warming and environmental pollution are increasingly pushing towards the replacement of road vehicles powered by Internal Combustion Engines (ICEs. Electric Vehicles (EVs are generally considered the best candidates for this transition, however, existing power grids and EV management systems are not yet ready for a large penetration of EVs, and the current opinion of the scientific community is that further research must be done in this field. The so-called Vehicle-to-Grid (V2G concept plays a relevant role in this scenario by providing the communication capabilities required by advanced control and Demand-Side Management (DSM strategies. Following this research trend, in this paper the communication requirements for the DSM of EVs in urban environments are discussed, by focusing on the mobile communication among EVs and smart grids. A specific system architecture for the DSM of EVs moving inside urban areas is proposed and discussed in terms of the required data throughput. In addition, the use of a Low-Power Wide-Area Network (LPWAN solution—the Long-Range Wide Area Network (LoRaWAN technology—is proposed as a possible alternative to cellular-like solutions, by testing an experimental communication infrastructure in a real environment. The results show that the proposed LPWAN technology is capable to handle an adequate amount of information for the considered application, and that one LoRa base station is able to serve up to 438 EVs per cell, and 1408 EV charging points.

Is this ?complicated? opioid withdrawal?

OpenAIRE

Parkar, S.R.; Seethalakshmi, R; Adarkar, S; Kharawala, S

2006-01-01

Seven patients with opioid dependence admitted in the de-addiction centre for detoxification developed convulsions and delirium during the withdrawal phase. After ruling out all other possible causes of these complications, opioid withdrawal seemed to emerge as the most likely explanation. The unpredictability of the course of opioid dependence and withdrawal needs to be considered when treating patients with opioid dependence.

Communication Disorders and Challenging Behaviors: Supporting Children's Functional Communication Goals in the Classroom

Science.gov (United States)

Gregg, Katy

2017-01-01

Children with communication disorders may express frustrations through challenging behaviors such as aggressive behaviors and social withdrawal. Challenging behaviors may lead to difficulties with building social competencies including emotional regulation and peer engagement. Individualized planning of functional goals for children with…

Conflict and Withdrawal during Marital Interaction: The Roles of Hostility and Defensiveness.

Science.gov (United States)

Newton, Tamara L.; And Others

1995-01-01

Examined whether hostile and defensive personality characteristics contribute to conflict and withdrawal within marriage. Analysis of 90 newly wed couples' discussions showed that, among husbands, high levels of hostility combined with low levels of defensiveness accompanied increased conflict. This same personality pattern led to an increase in…

The Communication Patterns of Chinese Students with Their Lecturers in an Australian University

Science.gov (United States)

Ai, Bin

2017-01-01

Chinese students are now the largest group of international students in the Australian higher education sector. The patterns of Chinese communication and education affect the ways that Chinese students engage with their lecturers and manage their learning relationships. A case study of these patterns provides a small window through which to…

Graduation and Withdrawal from RN Programs. A Report of the Nurse Career-Pattern Study.

Science.gov (United States)

Knopf, Lucille

Based on a larger longitudinal study, this document examines three nursing groups--those entering schools preparing registered nurses in 1962, 1965, and 1967. It describes and compares those who graduated and those who withdrew before graduation and examines the reasons why the students withdraw from both the students' and the program directors'…

Generation of predictive price and trading volume patterns in a model of dynamically evolving free market supply and demand

Directory of Open Access Journals (Sweden)

J. K. Wang

2001-01-01

Full Text Available I present a model of stock market price fluctuations incorporating effects of share supply as a history-dependent function of previous purchases and share demand as a function of price deviation from moving averages. Price charts generated show intervals of oscillations switching amplitude and frequency suddenly in time, forming price and trading volume patterns well-known in market technical analysis. Ultimate price trends agree with traditional predictions for specific patterns. The consideration of dynamically evolving supply and demand in this model resolves the apparent contradiction with the Efficient Market Hypothesis: perceptions of imprecise equity values by a world of investors evolve over non-negligible periods of time, with dependence on price history.

19 CFR 144.38 - Withdrawal for consumption.

Science.gov (United States)

2010-04-01

... 19 Customs Duties 2 2010-04-01 2010-04-01 false Withdrawal for consumption. 144.38 Section 144.38... Withdrawal for consumption. (a) Form. Withdrawals for consumption of merchandise in bonded warehouses shall... considered a withdrawal for consumption pursuant to § 181.53 of this chapter. (c) Information to be shown on...

Patient-Physician Communicative Patterns, Physicians’ Job Satisfaction, and Patients’ Satisfaction: The Case of a Hospital in Isfahan

Directory of Open Access Journals (Sweden)

Maryam Yaghoubi

2014-04-01

Full Text Available Abstract Background and purpose:Now-a-days, patient satisfaction is increasingly receiving the attention of health-service providers, which is a necessary step to enhance the quality of health services. The present study aimed at exploring patient-physician communicative patterns, physicians’ job satisfaction, and patients’ satisfaction at Isfahan, Iran. Materials and Methods:This study was a descriptive analytical and cross-sectional survey in the summer of 2010. Simple random sampling was used to select participants. Data were collected through using three self-designed questionnaires on physicians’ job satisfaction, patient-physician relationship patterns (based on Hollander and Szase’ ideas, and patients’ satisfaction. Validity of the questionnaire was checked by a panel of experts. Furthermore, internal consistency reliability of the questionnaires was confirmed by Cronbach’s alpha (α = 0.80. Different dimensions of the job satisfaction questionnaire were salary, supervision, setting, promotion, fringe benefits, and working conditions. Data were analyzed by using SPSS for Windows 13.0 software. Results:The mean score of patient-physician relationship was 63. Therefore, the most frequent patient-physician communication pattern was guidance-cooperation. The mean score of physician’ job satisfaction was 50.2. The mean score of patients’ satisfaction was 86.5. Physicians’ job satisfaction was found to be related to patient-physician communication pattern (P < 0.05. Conclusion:Although patient-physician communication patterns are important, different variable such as patients’ and physicians’ satisfaction influence the patterns. Furthermore, improvement communication process between health care providers can be useful in the increasing patient satisfaction and patient quality of care.

Cross-Cultural Communication Patterns in Computer Mediated Communication

Science.gov (United States)

Panina, Daria; Kroumova, Maya

2015-01-01

There are important cultural differences in attitudes towards and use of electronic text communication. Consistent with Hall's high-context/low-context conceptualization of culture, electronic inter-cultural communication, just as verbal inter-cultural communication, is affected by the culturally-specific assumptions and preferences of message…

Simulating the effects of ground-water withdrawals on streamflow in a precipitation-runoff model

Science.gov (United States)

Zarriello, Philip J.; Barlow, P.M.; Duda, P.B.

2004-01-01

Precipitation-runoff models are used to assess the effects of water use and management alternatives on streamflow. Often, ground-water withdrawals are a major water-use component that affect streamflow, but the ability of surface-water models to simulate ground-water withdrawals is limited. As part of a Hydrologic Simulation Program-FORTRAN (HSPF) precipitation-runoff model developed to analyze the effect of ground-water and surface-water withdrawals on streamflow in the Ipswich River in northeastern Massachusetts, an analytical technique (STRMDEPL) was developed for calculating the effects of pumped wells on streamflow. STRMDEPL is a FORTRAN program based on two analytical solutions that solve equations for ground-water flow to a well completed in a semi-infinite, homogeneous, and isotropic aquifer in direct hydraulic connection to a fully penetrating stream. One analytical method calculates unimpeded flow at the stream-aquifer boundary and the other method calculates the resistance to flow caused by semipervious streambed and streambank material. The principle of superposition is used with these analytical equations to calculate time-varying streamflow depletions due to daily pumping. The HSPF model can readily incorporate streamflow depletions caused by a well or surface-water withdrawal, or by multiple wells or surface-water withdrawals, or both, as a combined time-varying outflow demand from affected channel reaches. These demands are stored as a time series in the Watershed Data Management (WDM) file. This time-series data is read into the model as an external source used to specify flow from the first outflow gate in the reach where these withdrawals are located. Although the STRMDEPL program can be run independently of the HSPF model, an extension was developed to run this program within GenScn, a scenario generator and graphical user interface developed for use with the HSPF model. This extension requires that actual pumping rates for each well be stored

A description of communication patterns during CPR in ICU.

Science.gov (United States)

Taylor, Katherine L; Ferri, Susan; Yavorska, Tatyana; Everett, Tobias; Parshuram, Christopher

2014-10-01

Deficiencies in communication in health care are a common source of medical error. Preferred communication patterns are a component of resuscitation teaching. We audio-recorded resuscitations in a mixed paediatric medical and surgical ICU to describe communication. In the intensive care unit, resuscitation events were prospectively audio-recorded by two trained observers (using handheld recorders). Recordings were transcribed and anonymised within 24h. We grouped utterances regarding the same subject matter from beginning (irrespective of response) as a communication epoch. For each epoch, we describe the initiator, audience and content of message. Teamwork behaviours were described using Anesthesia Nontechnical Skills framework (ANTS), a behavioural marker system for crisis-resource management. Consent rates from staff were 139/140 (99%) and parents were 67/92 (73%). We analysed 36min 57s of audio dialogue from 4 cardiac arrest events in 363h of prospective screening. There were 180 communication epochs (1 every 12s): 100 (56%) from the team-leader and 80 (44%) from non-team-leader(s). Team-leader epochs were to give or confirm orders or assert authority (61%), clarify patient history (14%) and provide clinical updates (25%). Non-team-leader epochs were more often directed to the team (65%) than the team-leader (35%). Audio-recordings provided information for 80% of the ANTS component elements with scores of 2-4. Communication epochs were frequent, most from the team-leader. We identified an 'outer loop' of communication between team members not including the team-leader, responsible for 44% of all communication events. We discuss difficulties in this research methodology. Future work includes exploring the process of the 'outer loop' by resuscitation team members to evaluate the optimal balance between single leader and team suggestions, the content of the outer loop discussions and in-event communication strategies to improve outcomes. Crown Copyright © 2014

Family Communication Patterns and Relational Maintenance Behavior: Direct and Mediated Associations with Friendship Closeness

Science.gov (United States)

Ledbetter, Andrew M.

2009-01-01

In this study, both face-to-face and online relational maintenance behaviors were tested as mediators of family communication patterns and closeness with a same-sex friend. Participants included 417 young adults recruited from communication courses at a large university in the Midwestern United States. The obtained structural model demonstrated…

Coupling Agent-Based and Groundwater Modeling to Explore Demand Management Strategies for Shared Resources

Science.gov (United States)

Al-Amin, S.

2015-12-01

Municipal water demands in growing population centers in the arid southwest US are typically met through increased groundwater withdrawals. Hydro-climatic uncertainties attributed to climate change and land use conversions may also alter demands and impact the replenishment of groundwater supply. Groundwater aquifers are not necessarily confined within municipal and management boundaries, and multiple diverse agencies may manage a shared resource in a decentralized approach, based on individual concerns and resources. The interactions among water managers, consumers, and the environment influence the performance of local management strategies and regional groundwater resources. This research couples an agent-based modeling (ABM) framework and a groundwater model to analyze the effects of different management approaches on shared groundwater resources. The ABM captures the dynamic interactions between household-level consumers and policy makers to simulate water demands under climate change and population growth uncertainties. The groundwater model is used to analyze the relative effects of management approaches on reducing demands and replenishing groundwater resources. The framework is applied for municipalities located in the Verde River Basin, Arizona that withdraw groundwater from the Verde Formation-Basin Fill-Carbonate aquifer system. Insights gained through this simulation study can be used to guide groundwater policy-making under changing hydro-climatic scenarios for a long-term planning horizon.

Toward Global Communication Networks: How Television is Forging New Thinking Patterns.

Science.gov (United States)

Adams, Dennis M.; Fuchs, Mary

1986-01-01

Recent alliances between communication providers and computer manufacturers will lead to new technological combinations that will deliver visually-based ideas and information to a worldwide audience. Urges that those in charge of future video programs to consider their effects on children's language skills, thinking patterns, and intellectual…

Quantitative work demands, emotional demands, and cognitive stress symptoms in surgery nurses.

Science.gov (United States)

Elfering, Achim; Grebner, Simone; Leitner, Monika; Hirschmüller, Anja; Kubosch, Eva Johanna; Baur, Heiner

2017-06-01

In surgery, cognitive stress symptoms, including problems in concentrating, deciding, memorising, and reflecting are risks to patient safety. Recent evidence points to social stressors as antecedents of cognitive stress symptoms in surgery personnel. The current study tests whether cognitive stress symptoms are positively associated with emotional abuse, emotional- and task-related demands and resources in surgery work. Forty-eight surgery nurses from two hospitals filled out the Copenhagen Psychosocial Questionnaire in its German version. Task-related and emotional demands were positively related to cognitive stress symptoms. In a stepwise, multiple, linear regression of cognitive stress symptoms on task-related and emotional demands, emotional abuse and emotional demands were unique predictors (p emotional abuse, emotional demands, and, therefore, communication and cooperation team climate in surgery personnel.

Effect of training the communication skills with cognitive-behavioral model to drug dependent couples on communication patterns and recurrent relapse

OpenAIRE

M. Rahbarian; R. Hossein zadeh; P. Doosti

2016-01-01

Background: One of the main challenges in methadone maintenance treatment is relapse and lack of sustainability on treatment. Therefore, considering the effective factors in this regard and reducing it through psychological interventions as an adjunct to medication is necessary. Objective: The current study aimed to determine the effectiveness of communication skill training based on cognitive-behavioral model on communication patterns and recurrent relapse in drug dependent couples. Me...

Ethanol demand in Brazil: Regional approach

International Nuclear Information System (INIS)

Freitas, Luciano Charlita de; Kaneko, Shinji

2011-01-01

Successive studies attempting to clarify national aspects of ethanol demand have assisted policy makers and producers in defining strategies, but little information is available on the dynamic of regional ethanol markets. This study aims to analyze the characteristics of ethanol demand at the regional level taking into account the peculiarities of the developed center-south and the developing north-northeast regions. Regional ethanol demand is evaluated based on a set of market variables that include ethanol price, consumer's income, vehicle stock and prices of substitute fuels; i.e., gasoline and natural gas. A panel cointegration analysis with monthly observations from January 2003 to April 2010 is employed to estimate the long-run demand elasticity. The results reveal that the demand for ethanol in Brazil differs between regions. While in the center-south region the price elasticity for both ethanol and alternative fuels is high, consumption in the north-northeast is more sensitive to changes in the stock of the ethanol-powered fleet and income. These, among other evidences, suggest that the pattern of ethanol demand in the center-south region most closely resembles that in developed nations, while the pattern of demand in the north-northeast most closely resembles that in developing nations. - Research highlights: → Article consists of a first insight on regional demand for ethanol in Brazil. → It proposes a model with multiple fuels, i.e., hydrous ethanol, gasohol and natural gas. → Results evidence that figures for regional demand for ethanol differ amongst regions and with values reported for national demand. → Elasticities for the center-south keep similarities to patterns for fuel demand in developed nations while coefficients for the north-northeast are aligned to patterns on developing countries.

Ethanol demand in Brazil: Regional approach

Energy Technology Data Exchange (ETDEWEB)

Freitas, Luciano Charlita de, E-mail: lucianofreitas@hiroshima-u.ac.j [Graduate School for International Development and Cooperation, Development Policy, Hiroshima University 1-5-1 Kagamiyama, Higashi-Hiroshima, Hiroshima 739-8529 (Japan); Kaneko, Shinji [Graduate School for International Development and Cooperation, Development Policy, Hiroshima University 1-5-1 Kagamiyama, Higashi-Hiroshima, Hiroshima 739-8529 (Japan)

2011-05-15

Successive studies attempting to clarify national aspects of ethanol demand have assisted policy makers and producers in defining strategies, but little information is available on the dynamic of regional ethanol markets. This study aims to analyze the characteristics of ethanol demand at the regional level taking into account the peculiarities of the developed center-south and the developing north-northeast regions. Regional ethanol demand is evaluated based on a set of market variables that include ethanol price, consumer's income, vehicle stock and prices of substitute fuels; i.e., gasoline and natural gas. A panel cointegration analysis with monthly observations from January 2003 to April 2010 is employed to estimate the long-run demand elasticity. The results reveal that the demand for ethanol in Brazil differs between regions. While in the center-south region the price elasticity for both ethanol and alternative fuels is high, consumption in the north-northeast is more sensitive to changes in the stock of the ethanol-powered fleet and income. These, among other evidences, suggest that the pattern of ethanol demand in the center-south region most closely resembles that in developed nations, while the pattern of demand in the north-northeast most closely resembles that in developing nations. - Research highlights: {yields} Article consists of a first insight on regional demand for ethanol in Brazil. {yields} It proposes a model with multiple fuels, i.e., hydrous ethanol, gasohol and natural gas. {yields} Results evidence that figures for regional demand for ethanol differ amongst regions and with values reported for national demand. {yields} Elasticities for the center-south keep similarities to patterns for fuel demand in developed nations while coefficients for the north-northeast are aligned to patterns on developing countries.

Development of water demand coefficients for power generation from renewable energy technologies

International Nuclear Information System (INIS)

Ali, Babkir; Kumar, Amit

2017-01-01

Highlights: • Water consumption and withdrawals coefficients for renewable power generation were developed. • Six renewable energy sources (biomass, nuclear, solar, wind, hydroelectricity, and geothermal) were studied. • Life cycle water footprints for 60 electricity generation pathways were considered. • Impact of cooling systems for some power generation pathways was assessed. - Abstract: Renewable energy technology-based power generation is considered to be environmentally friendly and to have a low life cycle greenhouse gas emissions footprint. However, the life cycle water footprint of renewable energy technology-based power generation needs to be assessed. The objective of this study is to develop life cycle water footprints for renewable energy technology-based power generation pathways. Water demand is evaluated through consumption and withdrawals coefficients developed in this study. Sixty renewable energy technology-based power generation pathways were developed for a comprehensive comparative assessment of water footprints. The pathways were based on the use of biomass, nuclear, solar, wind, hydroelectricity, and geothermal as the source of energy. During the complete life cycle, power generation from bio-oil extracted from wood chips, a biomass source, was found to have the highest water demand footprint and wind power the lowest. During the complete life cycle, the water demand coefficients for biomass-based power generation pathways range from 260 to 1289 l of water per kilowatt hour and for nuclear energy pathways from 0.48 to 179 l of water per kilowatt hour. The water demand for power generation from solar energy-based pathways ranges from 0.02 to 4.39 l of water per kilowatt hour, for geothermal pathways from 0.04 to 1.94 l of water per kilowatt hour, and for wind from 0.005 to 0.104 l of water per kilowatt hour. A sensitivity analysis was conducted with varying conversion efficiencies to evaluate the impact of power plant performance on

Anticonvulsants for alcohol withdrawal.

Science.gov (United States)

Minozzi, Silvia; Amato, Laura; Vecchi, Simona; Davoli, Marina

2010-03-17

Alcohol abuse and dependence represents a most serious health problem worldwide with major social, interpersonal and legal interpolations. Besides benzodiazepines, anticonvulsants are often used for the treatment of alcohol withdrawal symptoms. Anticonvulsants drugs are indicated for the treatment of alcohol withdrawal syndrome, alone or in combination with benzodiazepine treatments. In spite of the wide use, the exact role of the anticonvulsants for the treatment of alcohol withdrawal has not yet bee adequately assessed. To evaluate the effectiveness and safety of anticonvulsants in the treatment of alcohol withdrawal. We searched Cochrane Drugs and Alcohol Group' Register of Trials (December 2009), PubMed, EMBASE, CINAHL (1966 to December 2009), EconLIT (1969 to December 2009). Parallel searches on web sites of health technology assessment and related agencies, and their databases. Randomized controlled trials (RCTs) examining the effectiveness, safety and overall risk-benefit of anticonvulsants in comparison with a placebo or other pharmacological treatment. All patients were included regardless of age, gender, nationality, and outpatient or inpatient therapy. Two authors independently screened and extracted data from studies. Fifty-six studies, with a total of 4076 participants, met the inclusion criteria. Comparing anticonvulsants with placebo, no statistically significant differences for the six outcomes considered.Comparing anticonvulsant versus other drug, 19 outcomes considered, results favour anticonvulsants only in the comparison carbamazepine versus benzodiazepine (oxazepam and lorazepam) for alcohol withdrawal symptoms (CIWA-Ar score): 3 studies, 262 participants, MD -1.04 (-1.89 to -0.20), none of the other comparisons reached statistical significance.Comparing different anticonvulsants no statistically significant differences in the two outcomes considered.Comparing anticonvulsants plus other drugs versus other drugs (3 outcomes considered), results

An investigation of communication patterns and strategies between international teaching assistants and undergraduate students in university-level science labs

Science.gov (United States)

Gourlay, Barbara Elas

This research project investigates communication between international teaching assistants and their undergraduate students in university-level chemistry labs. During the fall semester, introductory-level chemistry lab sections of three experienced non-native speaking teaching assistants and their undergraduate students were observed. Digital audio and video recordings documented fifteen hours of lab communication, focusing on the activities and interactions in the first hour of the chemistry laboratory sessions. In follow-up one-on-one semi-structured interviews, the participants (undergraduates, teaching assistants, and faculty member) reviewed interactions and responded to a 10-item, 7-point Likert-scaled interview. Interactions were classified into success categories based on participants' opinions. Quantitative and qualitative data from the observations and interviews guided the analysis of the laboratory interactions, which examined patterns of conversational listening. Analysis of laboratory communication reveals that undergraduates initiated nearly two-thirds of laboratory communication, with three-fourths of interactions less than 30 seconds in duration. Issues of gender and topics of interaction activity were also explored. Interview data identified that successful undergraduate-teaching assistant communication in interactive science labs depends on teaching assistant listening comprehension skills to interpret and respond successfully to undergraduate questions. Successful communication in the chemistry lab depended on the coordination of visual and verbal sources of information. Teaching assistant responses that included explanations and elaborations were also seen as positive features in the communicative exchanges. Interaction analysis focusing on the listening comprehension demands placed on international teaching assistants revealed that undergraduate-initiated questions often employ deixis (exophoric reference), requiring teaching assistants to

Crisis Communication during Natural Disasters: Meeting Real and Perceived Needs

Science.gov (United States)

Jones, L.

2017-12-01

When significant natural disasters strike, our modern information-driven society turns to scientists, demanding information about the event. As part of their civic duty scientists respond, recognizing how the scientific information could be used to improve response to the disaster and reduce losses. However, what we often find is that the demand for information is not for improved response but to satisfy psychological, often subconscious needs. Human beings evolved our larger brains to better survive against larger and stronger predators. Recognizing that a movement of grass and the lack of birdsong means that a predator is hiding would in turn mean a greater likelihood of having progeny. Our ability to theorize comes from the need to create patterns in the face of danger that will keep us safe. From wondering about someone's exercise habits when we hear they have a heart attack, to blaming hurricane victims for not heeding evacuation orders even if they had no means to evacuate, we respond to disasters by trying to make a pattern that means that we will not suffer the same fate. Much of the demand for information after a natural disaster is a search for these patterns. Faced with a random distribution, many people still make patterns that can reduce their anxiety. The result is that meanings are ascribed to the information that is not supported by the data and was not part of the communication as intended by the scientist. The challenge for science communicators is to recognize this need and present the information is a way that both reduces the anxiety that arises from a lack of knowledge or uncertainty while making clear what patterns can or cannot be made about future risks.

Information and communication technology demands at work : the association with job strain, effort-reward imbalance and self-rated health in different socio-economic strata

OpenAIRE

Stadin, Magdalena; Nordin, Maria; Broström, Anders; Magnusson Hanson, Linda L.; Westerlund, Hugo; Fransson, Eleonor I.

2016-01-01

The use of information and communication technology (ICT) is common in modern working life. ICT demands may give rise to experience of work-related stress. Knowledge about ICT demands in relation to other types of work-related stress and to self-rated health is limited. Consequently, the aim of this study was to examine the association between ICT demands and two types of work-related stress [job strain and effort-reward imbalance (ERI)] and to evaluate the association between these work-rela...

Observing Consistency in Online Communication Patterns for User Re-Identification.

Science.gov (United States)

Adeyemi, Ikuesan Richard; Razak, Shukor Abd; Salleh, Mazleena; Venter, Hein S

2016-01-01

Comprehension of the statistical and structural mechanisms governing human dynamics in online interaction plays a pivotal role in online user identification, online profile development, and recommender systems. However, building a characteristic model of human dynamics on the Internet involves a complete analysis of the variations in human activity patterns, which is a complex process. This complexity is inherent in human dynamics and has not been extensively studied to reveal the structural composition of human behavior. A typical method of anatomizing such a complex system is viewing all independent interconnectivity that constitutes the complexity. An examination of the various dimensions of human communication pattern in online interactions is presented in this paper. The study employed reliable server-side web data from 31 known users to explore characteristics of human-driven communications. Various machine-learning techniques were explored. The results revealed that each individual exhibited a relatively consistent, unique behavioral signature and that the logistic regression model and model tree can be used to accurately distinguish online users. These results are applicable to one-to-one online user identification processes, insider misuse investigation processes, and online profiling in various areas.

Perinatal risk factors and social withdrawal behaviour.

Science.gov (United States)

Guedeney, Antoine; Marchand-Martin, Laetitia; Cote, Sylvana J; Larroque, Béatrice

2012-04-01

The objectives of the study were (1) to assess prevalence of social withdrawal behaviour in infants aged 12 months included in the French Perinatal Risk Factor Study Eden; (2) To study the correlation between relational withdrawal and several perinatal and parental factors assessed in the EDEN study. A longitudinal study using the ADBB scale was conducted within the Eden Cohort in the year 2008. 1,586 infants were included in the study. Fourteen percent of the children who had an ADBB assessment had a score at 5 and over on the ADBB, a scale designed to assess social withdrawal behaviour at age 0-24 months. Social withdrawal at 12 months was associated with low birth weight, low gestational age and with intra uterine growth retardation. Social withdrawal was independently associated with several maternal and paternal risk factors. The level of social withdrawal behaviour increased with a score of maternal difficulties. This study on a large longitudinally followed volunteer sample demonstrate a clear association of social withdrawal behaviour at age one with low birth weight and preterm birth, possibly mediated by parental vulnerabilities. Social withdrawal behaviour seems to be an important alarm signal to detect early on particularly in premature and small for date babies. © Springer-Verlag 2012

Demand for electrical energy

International Nuclear Information System (INIS)

Bergougnoux, J.; Fouquet, D.

1983-01-01

The different utilizations of electric energy are reviewed in the residential and tertiary sectors, in the industry. The competitive position of electricity in regard to other fuels has been strengthned by the sudden rise in the price of oil in 1973-1974 and 1979-1980. The evolution of electricity prices depended on the steps taken to adjust the electricity generation system. The substitution of electricity applications for hydro-carbons is an essential point of energy policy. The adjustment at all times, at least cost and most reliability, of the supply of electricity to the demand for it is a major problem in the design and operation of electric systems. National demand for power at a given moment is extremely diversified. Electricity consumption presents daily and seasonal variations, and variations according to the different sectors. Forecasting power requirements is for any decision on operation or investment relating to an electrical system. Load management is desirable (prices according to the customers, optional tariffs for ''peak-day withdrawal''). To conclude, prospects for increased electricity consumption are discussed [fr

Optical wireless communications an emerging technology

CERN Document Server

Capsoni, Carlo; Ghassemlooy, Zabih; Boucouvalas, Anthony; Udvary, Eszter

2016-01-01

This book focuses on optical wireless communications (OWC), an emerging technology with huge potential for the provision of pervasive and reliable next-generation communications networks. It shows how the development of novel and efficient wireless technologies can contribute to a range of transmission links essential for the heterogeneous networks of the future to support various communications services and traffic patterns with ever-increasing demands for higher data-transfer rates. The book starts with a chapter reviewing the OWC field, which explains different sub-technologies (visible-light, ultraviolet (UV) and infrared (IR) communications) and introduces the spectrum of application areas (indoor, vehicular, terrestrial, underwater, intersatellite, deep space, etc.). This provides readers with the necessary background information to understand the specialist material in the main body of the book, which is in four parts. The first of these deals with propagation modelling and channel characterization of ...

Clinical management of alcohol withdrawal: A systematic review

Directory of Open Access Journals (Sweden)

Shivanand Kattimani

2013-01-01

Full Text Available Alcohol withdrawal is commonly encountered in general hospital settings. It forms a major part of referrals received by a consultation-liaison psychiatrist. This article aims to review the evidence base for appropriate clinical management of the alcohol withdrawal syndrome. We searched Pubmed for articles published in English on pharmacological management of alcohol withdrawal in humans with no limit on the date of publication. Articles not relevant to clinical management were excluded based on the titles and abstract available. Full-text articles were obtained from this list and the cross-references. There were four meta-analyses, 9 systematic reviews, 26 review articles and other type of publications like textbooks. Alcohol withdrawal syndrome is a clinical diagnosis. It may vary in severity. Complicated alcohol withdrawal presents with hallucinations, seizures or delirium tremens. Benzodiazepines have the best evidence base in the treatment of alcohol withdrawal, followed by anticonvulsants. Clinical institutes withdrawal assessment-alcohol revised is useful with pitfalls in patients with medical comorbidities. Evidence favors an approach of symptom-monitored loading for severe withdrawals where an initial dose is guided by risk factors for complicated withdrawals and further dosing may be guided by withdrawal severity. Supportive care and use of vitamins is also discussed.

The Relationship Between Family Communication Patterns and Frequency and Intensity of Parent-Adolescent Conflict

Directory of Open Access Journals (Sweden)

خدیجه جعفرنژاد

2015-11-01

Full Text Available This study examined the role of family communication patterns (conversation and conformity orientation to predict frequency and intensity of parent adolescent conflict. Participants included 189 students (37 girls and 116 boys selected from Birjand high schools. The measures of study include Asadi Younsi Parent-Adolescent Conflict Questionnaire (2011 and Koerner and Fitzpatrick Revised Version of Family Communication Patterns Instrument (2002. Alpha Cronbach were calculated to examine reliability of the measures. Pearson’s correlation and regression analysis were performed for the data analysis. Results indicated: A conversation orientation was a negative predictor of intensity conflict in girls and boys; B conformity orientation was significant and positive predictor of intensity conflict in boys. Thus the importance of education in the field of adolescent behavior and interaction with parents and families to improve the quality of communication skills can be a deterrent in reducing conflicts between parents and Adolescents.

Does teaching method affect students' perceptions regarding communication patterns in pediatric dentistry? A comparison of lecture and video methods.

Science.gov (United States)

Kalwitzki, Matthias; Meller, Christina; Beyer, Christine

2011-08-01

The purpose of this study was to determine whether dental students' perceptions regarding six communication patterns for use in pediatric dentistry differed depending on whether they were taught by lecturing or by video-based teaching. Prior to the introduction of interpersonal skills in a clinical course in pediatric dentistry, four consecutive cohorts of students (n=107) in a German dental school were divided equally into two groups. Group one (n=57) was taught by video sequences and group two (n=50) by conventional lecture. Six communication patterns were presented: involvement of the child's toy(s), speaking in positive phrases, mentioning a personal aspect, recalling positive behavior of the patient, addressing fear verbally, and complimenting the patient. Immediately after the presentation, students were asked by means of a questionnaire about their assessment of and intentions regarding the clinical application of the communication patterns presented. After completion of the course, they were asked about the communication patterns that had been used. There were significant differences for three communication patterns in favor of video-based teaching (pstudents perceived differences between video-based teaching and lecturing regarding ease of use, but they did not seem to benefit from one method over the other regarding clinical application.

Leaders' Communication Pattern: A Predictor of Lecturers' Job Performance in Nigeria

Science.gov (United States)

Oluwatoyin, Fashiku Christopher

2016-01-01

The study investigated the influence leaders' communication pattern has on lecturers' job performance in Kwara State Colleges of Education, Nigeria. Using the descriptive survey method, the population of the study was made up of all lecturers and students of the existing three state government owned Colleges of Education in the state. Five hundred…

Visualized study on specific points on demand curves and flow patterns in a single-side heated narrow rectangular channel

International Nuclear Information System (INIS)

Wang Junfeng; Huang Yanping; Wang Yanlin

2011-01-01

Highlights: → Specific points on the demand curve and flow patterns are visually studied. → Bubbly, churn, and annular flows were observed. → Onset of flow instability and bubbly-churn transition occurs at the same time. → The evolution of specific points and flow pattern transitions were examined. - Abstract: A simultaneous visualization and measurement study on some specific points on demand curves, such as onset of nucleate boiling (ONB), onset of significant void (OSV), onset of flow instability (OFI), and two-phase flow patterns in a single-side heated narrow rectangular channel, having a width of 40 mm and a gap of 3 mm, was carried out. New experimental approaches were adopted to identify OSV and OFI in a narrow rectangular channel. Under experimental conditions, the ONB could be predicted well by the Sato and Matsumura model. The OSV model of Bowring can reasonably predict the OSV if the single-side heated condition is considered. The OFI was close to the saturated boiling point and could be described accurately by Kennedy's correlation. The two-phase flow patterns observed in this experiment could be classified into bubbly, churn, and annular flow. Slug flow was never observed. The OFI always occurred when the bubbles at the channel exit began to coalesce, which corresponded to the beginning of the bubbly-churn transition in flow patterns. Finally, the evolution of specific points and flow pattern transitions were examined in a single-side heated narrow rectangular channel.

Prediction of withdrawal symptoms during opioid detoxification

NARCIS (Netherlands)

Dijkstra, Boukje A G; Krabbe, Paul F M; De Jong, Cor A J; van der Staak, Cees P F

2008-01-01

OBJECTIVE: The severity of self-reported withdrawal symptoms varies during detoxification of opioid-dependent patients. The aim of this study is to identify subgroups of withdrawal symptoms within the detoxification trajectory and to predict the severity of withdrawal symptoms on the basis of

Prediction of withdrawal symptoms during opioid detoxification

NARCIS (Netherlands)

Dijkstra, B.A.G.; Krabbe, P.F.M.; Jong, C.A.J. de; Staak, C.P.F. van der

2008-01-01

Objective: The severity of self-reported withdrawal symptoms varies during detoxification of opioid-dependent patients. The aim of this study is to identify subgroups of withdrawal symptoms within the detoxification trajectory and to predict the severity of withdrawal symptoms on the basis of

Communication patterns and satisfaction levels in three-dimensional versus real-life intimate relationships.

Science.gov (United States)

Gilbert, Richard L; Murphy, Nora A; Ávalos, M Clementina

2011-10-01

The present study compared communication patterns and satisfaction levels between three-dimensional (3D) and real-life intimate relationships using a sample of 71 participants who were concurrently involved in an intimate relationship within Second Life and a separate real-life romantic relationship. Participants indicated that the quality of their communication was significantly better in their Second-Life relationship and that they experienced higher levels of satisfaction with their virtual partners. The more positive or idealized view of the 3D relationships may have been due to higher levels of focused interaction and reduced stressors in the virtual world and the greater length, and associated problems, in participant's real-life relationships. In addition, the presence of a concurrent relationship within Second Life could have negatively affected participant's judgments of their real-life relationships. These data offer the first detailed assessment of communication patterns and satisfaction levels in intimate relationships across the real and 3D virtual realms as the number of users and romantic partners in immersive virtual environments continue to grow.

Communication patterns within a group of shelter dogs and implications for their welfare.

Science.gov (United States)

Petak, Irena

2013-01-01

Keeping shelter dogs in groups provides them with a more socially and physically enriched environment, but eventually it may cause them stress. Understanding dogs' communication could help shelter staff recognize and prevent undesirable communicative patterns and encourage desirable ones. Therefore, the objective of this study was to determine communication patterns in a group of dogs in a shelter. The observed dogs were engaged in different classes of dyadic and group interactions. Certain dogs were frequently initiators of dyadic interactions, and different dogs were the recipients. The predominant form of dyadic interactions was a neutral one, and aggressive behavior was rarely observed. The tendency of certain dogs to interact continuously may represent a nuisance for less social individuals. All of the dogs participated in 3 defined classes of group interactions. At the group level, the dogs frequently interact vocally or olfactorily. A major welfare problem may be very vocal dogs because their vocalizations are noisy and broadcast far-reaching signals. The frequency of some group interactions was reduced by the amount of time the dogs had in the shelter.

Impacts of impervious cover, water withdrawals, and climate change on river flows in the conterminous US

Directory of Open Access Journals (Sweden)

P. V. Caldwell

2012-08-01

demand for water, relocation of agricultural production, and/or water conservation measures. Given that the impacts of land use, withdrawals and climate may be either additive or offsetting in different magnitudes, integrated and spatially explicit modeling and management approaches are necessary to effectively manage water resources for aquatic life and human use in the face of global change.

Why do care workers withdraw from elderly care?

DEFF Research Database (Denmark)

Liveng, Anne

2012-01-01

. The article illustrates how working consciously with the researcher's subjectivity makes it possible to understand apparently irrational patterns. The insights thus gained may be used to prevent withdrawals in care work as an argument for care workers' need for emotional supervision....... relations, independently of whether we are in the role of care providers or care receivers. Through collusion theory, the interpretation accepts both the anxiety which the helpless elderly people arouse in the care workers and their motivation for care work as two sides of a subjectively important theme...

Control rod excess withdrawal prevention device

International Nuclear Information System (INIS)

Takayama, Yoshihito.

1992-01-01

Excess withdrawal of a control rod of a BWR type reactor is prevented. That is, the device comprises (1) a speed detector for detecting the driving speed of a control rod, (2) a judging circuit for outputting an abnormal signal if the driving speed is greater than a predetermined level and (3) a direction control valve compulsory closing circuit for controlling the driving direction of inserting and withdrawing a control rod based on an abnormal signal. With such a constitution, when the with drawing speed of a control rod is greater than a predetermined level, it is detected by the speed detector and the judging circuit. Then, all of the direction control valve are closed by way of the direction control valve compulsory closing circuit. As a result, the operation of the control rod is stopped compulsorily and the withdrawing speed of the control rod can be lowered to a speed corresponding to that upon gravitational withdrawal. Accordingly, excess withdrawal can be prevented. (I.S)

19 CFR 144.37 - Withdrawal for exportation.

Science.gov (United States)

2010-04-01

...) Class 9 warehouse withdrawals for exportation—(1) Applicability of sales ticket procedure. Merchandise... be eligible for withdrawal under the sales ticket procedure specified in this paragraph. (2) Sales ticket content and handling. Sales ticket withdrawals must be made only under a blanket permit to...

Mapping the online communication patterns of political conversations

Science.gov (United States)

Borondo, J.; Morales, A. J.; Benito, R. M.; Losada, J. C.

2014-11-01

The structure of the social networks in which individuals are embedded influences their political choices and therefore their voting behavior. Nowadays, social media represent a new channel for individuals to communicate, what together with the availability of the data, makes it possible to analyze the online social network resulting from political conversations. Here, by taking advantage of the recently developed techniques to analyze complex systems, we map the communication patterns resulting from Spanish political conversations. We identify the different existing communities, building networks of communities, and finding that users cluster themselves in politically homogeneous networks. We found that while most of the collective attention was monopolized by politicians, traditional media accounts were still the preferred sources from which to propagate information. Finally, we propose methods to analyze the use of different languages, finding a clear trend from sympathizers of several political parties to overuse or infra-use each language. We conclude that, on the light of a social media analysis perspective, the political conversation is constrained by both ideology and language.

5 CFR 362.207 - Withdrawal and readmission.

Science.gov (United States)

2010-01-01

... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Withdrawal and readmission. 362.207... PRESIDENTIAL MANAGEMENT FELLOWS PROGRAM Program Administration § 362.207 Withdrawal and readmission. (a...) An agency must notify OPM when a Fellow or Senior Fellow withdraws from the Program. (b) Readmission...

Tobacco withdrawal among opioid-dependent smokers.

Science.gov (United States)

Streck, Joanna M; Heil, Sarah H; Higgins, Stephen T; Bunn, Janice Y; Sigmon, Stacey C

2018-04-01

Prevalence of cigarette smoking among opioid-dependent individuals is 6-fold that of the general U.S. adult population and their quit rates are notoriously poor. One possible reason for the modest cessation outcomes in opioid-dependent smokers may be that they experience more severe tobacco withdrawal upon quitting. In this secondary analysis, we evaluated tobacco withdrawal in opioid-dependent (OD) smokers versus smokers without co-occurring substance use disorders (SUDs). Participants were 47 methadone- or buprenorphine-maintained smokers and 25 non-SUD smokers who completed 1 of several 2-week studies involving daily visits for biochemical monitoring, delivery of financial incentives contingent on smoking abstinence, and assessment of withdrawal via the Minnesota Nicotine Withdrawal Scale (MNWS). Prior to quitting smoking, OD smokers presented with higher baseline withdrawal scores than non-SUD smokers (1.7 ± 0.2 vs. 0.7 ± 0.2, respectively; F [1, 63] = 7.31, p non-SUD smokers, suggesting that elevated withdrawal severity following quitting may not be a major factor contributing to the poor cessation outcomes consistently observed among OD smokers. Further scientific efforts are needed to improve our understanding of the high smoking rates and modest cessation outcomes in this challenging population. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

Open Automated Demand Response for Small Commerical Buildings

Energy Technology Data Exchange (ETDEWEB)

Dudley, June Han; Piette, Mary Ann; Koch, Ed; Hennage, Dan

2009-05-01

This report characterizes small commercial buildings by market segments, systems and end-uses; develops a framework for identifying demand response (DR) enabling technologies and communication means; and reports on the design and development of a low-cost OpenADR enabling technology that delivers demand reductions as a percentage of the total predicted building peak electric demand. The results show that small offices, restaurants and retail buildings are the major contributors making up over one third of the small commercial peak demand. The majority of the small commercial buildings in California are located in southern inland areas and the central valley. Single-zone packaged units with manual and programmable thermostat controls make up the majority of heating ventilation and air conditioning (HVAC) systems for small commercial buildings with less than 200 kW peak electric demand. Fluorescent tubes with magnetic ballast and manual controls dominate this customer group's lighting systems. There are various ways, each with its pros and cons for a particular application, to communicate with these systems and three methods to enable automated DR in small commercial buildings using the Open Automated Demand Response (or OpenADR) communications infrastructure. Development of DR strategies must consider building characteristics, such as weather sensitivity and load variability, as well as system design (i.e. under-sizing, under-lighting, over-sizing, etc). Finally, field tests show that requesting demand reductions as a percentage of the total building predicted peak electric demand is feasible using the OpenADR infrastructure.

On the relationship between Indian monsoon withdrawal and Iran's fall precipitation onset

Science.gov (United States)

Babaeian, Iman; Rezazadeh, Parviz

2017-09-01

Indian monsoon is the most prominent of the world's monsoon systems which primarily affects synoptic patterns of India and adjacent countries such as Iran in interaction with large-scale weather systems. In this article, the relationship between the withdrawal date of the Indian monsoon and the onset of fall precipitation in Iran has been studied. Data included annual time series of withdrawal dates of the Indian monsoon prepared by the Indian Institute for Tropical Meteorology, and time series of the first date of 25 mm accumulated precipitation over Iran's synoptic weather stations in a 10-day period which is the basis for the cultivation date. Both time series were considered in Julian calendar with the starting date on August 1. The studied period is 1960-2014 which covers 55 years of data from 36 meteorological stations in Iran. By classifying the withdrawal dates of the Indian monsoon in three stages of late, normal, and early withdrawals, its relation with the onset of fall precipitation in western, southwestern, southern, eastern, central, and northern regions of Iran was studied. Results demonstrated that in four out of the six mentioned regions, the late withdrawal of the Indian monsoon postpones the onset of fall precipitation over Iran. No significant relation was found between the onset of fall precipitation in central region of Iran and the monsoon's withdrawal date. In the western, southwestern, southern, and eastern regions of Iran, the late monsoon delays the onset of fall's precipitation; while in the south Caspian Sea coastal area, it causes the early onset of autumnal precipitation. The lag in onset of fall precipitation in Iran which is coordinated with the late withdrawal of monsoon is accompanied with prolonged subtropical high settling over Iran's plateau that prevents the southward movement of polar jet frontal systems. Such conditions enhance northerly wind currents over the Caspian Sea which, in turn, increase the precipitation in Caspian

Water withdrawals in Florida, 2012

Science.gov (United States)

Marella, Richard L.

2015-09-01

In 2012, the total amount of water withdrawn in Florida was estimated to be 14,237 million gallons per day (Mgal/d). Saline water accounted for 7,855 Mgal/d (55 percent), and freshwater accounted for 6,383 Mgal/d (45 percent). Groundwater accounted for 4,167 Mgal/d (65 percent) of freshwater withdrawals, and surface water accounted for the remaining 2,216 Mgal/d (35 percent). Surface water accounted for nearly all (99.9 percent) saline-water withdrawals. Freshwater withdrawals were greatest in Palm Beach County (682 Mgal/d), and saline-water withdrawals were greatest in Pasco County (1,822 Mgal/d). Fresh groundwater provided drinking water (through either public supply or private domestic wells) for 17.699 million residents (93 percent of Florida’s population), and fresh surface water provided drinking water for 1.375 million residents (7 percent). The statewide public-supply gross per capita water use for 2012 was estimated at 136 gallons per day.

29 CFR 102.104 - Withdrawal of petition.

Science.gov (United States)

2010-07-01

... 29 Labor 2 2010-07-01 2010-07-01 false Withdrawal of petition. 102.104 Section 102.104 Labor... Orders and Advisory Opinions Regarding Board Jurisdiction § 102.104 Withdrawal of petition. The petitioner may withdraw his petition at any time prior to issuance of the Board's advisory opinion. ...

Quantifying the Clinical Significance of Cannabis Withdrawal

Science.gov (United States)

Allsop, David J.; Copeland, Jan; Norberg, Melissa M.; Fu, Shanlin; Molnar, Anna; Lewis, John; Budney, Alan J.

2012-01-01

Background and Aims Questions over the clinical significance of cannabis withdrawal have hindered its inclusion as a discrete cannabis induced psychiatric condition in the Diagnostic and Statistical Manual of Mental Disorders (DSM IV). This study aims to quantify functional impairment to normal daily activities from cannabis withdrawal, and looks at the factors predicting functional impairment. In addition the study tests the influence of functional impairment from cannabis withdrawal on cannabis use during and after an abstinence attempt. Methods and Results A volunteer sample of 49 non-treatment seeking cannabis users who met DSM-IV criteria for dependence provided daily withdrawal-related functional impairment scores during a one-week baseline phase and two weeks of monitored abstinence from cannabis with a one month follow up. Functional impairment from withdrawal symptoms was strongly associated with symptom severity (p = 0.0001). Participants with more severe cannabis dependence before the abstinence attempt reported greater functional impairment from cannabis withdrawal (p = 0.03). Relapse to cannabis use during the abstinence period was associated with greater functional impairment from a subset of withdrawal symptoms in high dependence users. Higher levels of functional impairment during the abstinence attempt predicted higher levels of cannabis use at one month follow up (p = 0.001). Conclusions Cannabis withdrawal is clinically significant because it is associated with functional impairment to normal daily activities, as well as relapse to cannabis use. Sample size in the relapse group was small and the use of a non-treatment seeking population requires findings to be replicated in clinical samples. Tailoring treatments to target withdrawal symptoms contributing to functional impairment during a quit attempt may improve treatment outcomes. PMID:23049760

Quantifying the clinical significance of cannabis withdrawal.

Directory of Open Access Journals (Sweden)

David J Allsop

Full Text Available Questions over the clinical significance of cannabis withdrawal have hindered its inclusion as a discrete cannabis induced psychiatric condition in the Diagnostic and Statistical Manual of Mental Disorders (DSM IV. This study aims to quantify functional impairment to normal daily activities from cannabis withdrawal, and looks at the factors predicting functional impairment. In addition the study tests the influence of functional impairment from cannabis withdrawal on cannabis use during and after an abstinence attempt.A volunteer sample of 49 non-treatment seeking cannabis users who met DSM-IV criteria for dependence provided daily withdrawal-related functional impairment scores during a one-week baseline phase and two weeks of monitored abstinence from cannabis with a one month follow up. Functional impairment from withdrawal symptoms was strongly associated with symptom severity (p=0.0001. Participants with more severe cannabis dependence before the abstinence attempt reported greater functional impairment from cannabis withdrawal (p=0.03. Relapse to cannabis use during the abstinence period was associated with greater functional impairment from a subset of withdrawal symptoms in high dependence users. Higher levels of functional impairment during the abstinence attempt predicted higher levels of cannabis use at one month follow up (p=0.001.Cannabis withdrawal is clinically significant because it is associated with functional impairment to normal daily activities, as well as relapse to cannabis use. Sample size in the relapse group was small and the use of a non-treatment seeking population requires findings to be replicated in clinical samples. Tailoring treatments to target withdrawal symptoms contributing to functional impairment during a quit attempt may improve treatment outcomes.

19 CFR 144.36 - Withdrawal for transportation.

Science.gov (United States)

2010-04-01

... 19 Customs Duties 2 2010-04-01 2010-04-01 false Withdrawal for transportation. 144.36 Section 144... § 144.36 Withdrawal for transportation. (a) Time limit. Merchandise may be withdrawn from warehouse for transportation to another port of entry if withdrawal for consumption or exportation can be accomplished at the...

Simulated effects of increased groundwater withdrawals in the Cave Springs area, Hixson, Tennessee

Science.gov (United States)

Haugh, Connor J.

2014-01-01

Concern for future water supplies in Tennessee has grown in recent years as a result of increased awareness of competing needs, the impact of droughts, and the need for more water to support growing populations. The U.S. Geological Survey conducts investigations to improve the knowledge about interactions of geology, climate, humans, and ecosystems with the water cycle, which is critical to understanding and optimizing water availability. The Hixson Utility District in Hamilton County, Tennessee, uses groundwater resources in the Cave Springs area as a water supply, withdrawing water from two well fields located at Cave Springs and Walkers Corner. Historically, Hixson Utility District has withdrawn about 5 million gallons per day (Mgal/d) at the Cave Springs well field and between 2 and 3 Mgal/d at the Walkers Corner well field. To assess the capacity of the groundwater resources in the Cave Springs area to meet future demands, four different scenarios of increased groundwater withdrawals were analyzed using computer model simulations.

Psychosis following Tramadol Withdrawal

OpenAIRE

Rajabizadeh, Ghodratolah; Kheradmand, Ali; Nasirian, Mansoureh

2009-01-01

Background: Tramadol is a centrally acting opioid analgesic used to treat moderate to sever pain. It has more advantage and less opioid adverse effects than conventional opioid analgesia. Case Report: This article reports a patient with tramadol dependency that had psychosis after tramadol withdrawal. Conclusion: By the increase of tramadol usage for relief of chronic pain, tramadol abuse and dependency is increased. Some of tramadol withdrawal symptoms are not related to opioid, for example ...

Chicago's water market: Dynamics of demand, prices and scarcity rents

Science.gov (United States)

Ipe, V.C.; Bhagwat, S.B.

2002-01-01

Chicago and its suburbs are experiencing an increasing demand for water from a growing population and economy and may experience water scarcity in the near future. The Chicago metropolitan area has nearly depleted its groundwater resources to a point where interstate conflicts with Wisconsin could accompany an increased reliance on those sources. Further, the withdrawals from Lake Michigan is limited by the Supreme Court decree. The growing demand and indications of possible scarcity suggest a need to reexamine the pricing policies and the dynamics of demand. The study analyses the demand for water and develops estimates of scarcity rents for water in Chicago. The price and income elasticities computed at the means are -0.002 and 0.0002 respectively. The estimated scarcity rents ranges from $0.98 to $1.17 per thousand gallons. The results indicate that the current prices do not fully account for the scarcity rents and suggest a current rate with in the range $1.53 to $1.72 per thousand gallons.

Methods for Estimating Water Withdrawals for Mining in the United States, 2005

Science.gov (United States)

Lovelace, John K.

2009-01-01

The mining water-use category includes groundwater and surface water that is withdrawn and used for nonfuels and fuels mining. Nonfuels mining includes the extraction of ores, stone, sand, and gravel. Fuels mining includes the extraction of coal, petroleum, and natural gas. Water is used for mineral extraction, quarrying, milling, and other operations directly associated with mining activities. For petroleum and natural gas extraction, water often is injected for secondary oil or gas recovery. Estimates of water withdrawals for mining are needed for water planning and management. This report documents methods used to estimate withdrawals of fresh and saline groundwater and surface water for mining during 2005 for each county and county equivalent in the United States, Puerto Rico, and the U.S. Virgin Islands. Fresh and saline groundwater and surface-water withdrawals during 2005 for nonfuels- and coal-mining operations in each county or county equivalent in the United States, Puerto Rico, and the U.S. Virgin Islands were estimated. Fresh and saline groundwater withdrawals for oil and gas operations in counties of six states also were estimated. Water withdrawals for nonfuels and coal mining were estimated by using mine-production data and water-use coefficients. Production data for nonfuels mining included the mine location and weight (in metric tons) of crude ore, rock, or mineral produced at each mine in the United States, Puerto Rico, and the U.S. Virgin Islands during 2004. Production data for coal mining included the weight, in metric tons, of coal produced in each county or county equivalent during 2004. Water-use coefficients for mined commodities were compiled from various sources including published reports and written communications from U.S. Geological Survey National Water-use Information Program (NWUIP) personnel in several states. Water withdrawals for oil and gas extraction were estimated for six States including California, Colorado, Louisiana, New

High-dose benzodiazepine dependence: a qualitative study of patients' perception on cessation and withdrawal.

Science.gov (United States)

Liebrenz, Michael; Gehring, Marie-Therese; Buadze, Anna; Caflisch, Carlo

2015-05-13

Benzodiazepine withdrawal syndrome has been reported following attempts to withdraw even from low or therapeutic doses and has been compared to barbiturate and alcohol withdrawal. This experience is known to deter patients from future cessation attempts. Research on other psychotropic substances shows that the reasons and motivations for withdrawal attempts - as well as the experiences surrounding those attempts - at least partially predict future efforts at discontinuation as well as relapse. We therefore aimed to qualitatively explore what motivates patients to discontinue this medication as well as to examine their experiences surrounding previous and current withdrawal attempts and treatment interventions in order to positively influence future help-seeking behavior and compliance. To understand these patients better, we conducted a series of 41 unstructured, narrative, in-depth interviews among adult Swiss patients with a long-term dependent use of benzodiazepines in doses equivalent to more than 40 mg diazepam per day and/or otherwise problematic use (mixing benzodiazepines, escalating dosage, recreational use or illegal purchase). Mayring's qualitative content analysis was used to evaluate findings. These high-dose benzodiazepine-dependent patients decision to change consumption patterns were affected by health concerns, the feeling of being addicted and social factors. Discontinuation attempts were frequent and not very successful with fast relapse. Withdrawal was perceived to be a difficult, complicated, and highly unpredictable process. The first attempt at withdrawal occurred at home and typically felt better than at the clinic. Inpatient treatment was believed to be more effective with long term treatment (approaches) than short term. Patients preferred gradual reduction of usage to abrupt cessation (and had experienced both). While no clear preferences for withdrawal were found for benzodiazepines with specific pharmacokinetic properties, participants

A study on family communication pattern and parenting styles with quality of life in adolescent

International Nuclear Information System (INIS)

Sanavi, F.S.; Baghbanian, A.; Shovey, M.F.; Moghaddam, A.A

2013-01-01

Objective: To investigate the relationship between parenting styles and family communication patterns with adolescent's quality of life. Methods: The cross-sectional study was carried out on 439 randomly selected adolescents in the city of Zahedan, Iran, from January to July 2011. The subjects were asked to complete the KIDSCREEN-52 health-related quality of life questionnaire, while their parents were asked to complete the Diana Brinder's Test to show their parenting styles. SPSS 15 was used to analyse data. Results: Most parents had authoritative parenting style (n=380; 86.6%). Pluralistic (n=170; 38.7%) and consensual (n=152; 34.6%) patterns were the most frequent styles of communication in families. Data suggested a significant relationship between parenting style and some dimensions of quality of life, including physical well-being, psychological well-being, social support and peers, and autonomy (p<0.05). There was also a significant relationship between family communication patterns and parent relation and home life (p<0.001) as well as autonomy (p<0.006). Conclusion: Families play a critical role in increasing adolescents, health-related quality-of-life. Effort should be made to address problems facing parents while raising their children. (author)

Implementing new technologies for public safety communication: competing frequency demands and standardization issues

Science.gov (United States)

Stevens, Kathryn J.

1997-01-01

Attempting to incorporate new technology into an existing environment is often very difficult. The problems are lengthy to resolve, wrought with confusion and seldom turn out like anyone expected. This document represents an overview of one such attempt. It outlines the general areas of concern which could be affected by a transition, and potential problems that may be encountered as a result of the effort. Over the past several decades, many local, state and federal agencies are pressing for more efficient use of frequency spectrums. The urgency of this issue has grown due to the demands of several groups wanting access to these channels for commercial use. Pager systems, cellular telephones, radio systems for private businesses all demand more space. Public safety agencies are starting to fear their needs will diminish in importance as the available channel spectrums are consumed by commercial ventures. How to share these channels, purchase appropriate equipment to meet your needs, and stay within a reasonable budget are not easy tasks. Public safety agencies who rely on communication networks in the performance of their jobs also know why encryption is important. Protecting the rights of citizens as police exchange information over the air, maintaining the integrity of an investigation and officer safety are all concerns police must address each time they use a radio.

Withdrawal-associated injury site pain (WISP): a descriptive case series of an opioid cessation phenomenon.

Science.gov (United States)

Rieb, Launette Marie; Norman, Wendy V; Martin, Ruth Elwood; Berkowitz, Jonathan; Wood, Evan; McNeil, Ryan; Milloy, M-J

2016-12-01

Withdrawal pain can be a barrier to opioid cessation. Yet, little is known about old injury site pain in this context. We conducted an exploratory mixed-methods descriptive case series using a web-based survey and in-person interviews with adults recruited from pain and addiction treatment and research settings. We included individuals who self-reported a past significant injury that was healed and pain-free before the initiation of opioids, which then became temporarily painful upon opioid cessation-a phenomenon we have named withdrawal-associated injury site pain (WISP). Screening identified WISP in 47 people, of whom 34 (72%) completed the descriptive survey, including 21 who completed qualitative interviews. Recalled pain severity scores for WISP were typically high (median: 8/10; interquartile range [IQR]: 2), emotionally and physically aversive, and took approximately 2 weeks to resolve (median: 14; IQR: 24 days). Withdrawal-associated injury site pain intensity was typically slightly less than participants' original injury pain (median: 10/10; IQR: 3), and more painful than other generalized withdrawal symptoms which also lasted approximately 2 weeks (median: 13; IQR: 25 days). Fifteen surveyed participants (44%) reported returning to opioid use because of WISP in the past. Participants developed theories about the etiology of WISP, including that the pain is the brain's way of communicating a desire for opioids. This research represents the first known documentation that previously healed, and pain-free injury sites can temporarily become painful again during opioid withdrawal, an experience which may be a barrier to opioid cessation, and a contributor to opioid reinitiation.

Team communication patterns in emergency resuscitation: a mixed methods qualitative analysis.

Science.gov (United States)

Calder, Lisa Anne; Mastoras, George; Rahimpour, Mitra; Sohmer, Benjamin; Weitzman, Brian; Cwinn, A Adam; Hobin, Tara; Parush, Avi

2017-12-01

In order to enhance patient safety during resuscitation of critically ill patients, we need to optimize team communication and enhance team situational awareness but little is known about resuscitation team communication patterns. The objective of this study is to understand how teams communicate during resuscitation; specifically to assess for a shared mental model (organized understanding of a team's relationships) and information needs. We triangulated 3 methods to evaluate resuscitation team communication at a tertiary care academic trauma center: (1) interviews; (2) simulated resuscitation observations; (3) live resuscitation observations. We interviewed 18 resuscitation team members about shared mental models, roles and goals of team members and procedural expectations. We observed 30 simulated resuscitation video recordings and documented the timing, source and destination of communication and the information category. We observed 12 live resuscitations in the emergency department and recorded baseline characteristics of the type of resuscitations, nature of teams present and type and content of information exchanges. The data were analyzed using a qualitative communication analysis method. We found that resuscitation team members described a shared mental model. Respondents understood the roles and goals of each team member in order to provide rapid, efficient and life-saving care with an overall need for situational awareness. The information flow described in the interviews was reflected during the simulated and live resuscitations with the most responsible physician and charting nurse being central to team communication. We consolidated communicated information into six categories: (1) time; (2) patient status; (3) patient history; (4) interventions; (5) assistance and consultations; 6) team members present. Resuscitation team members expressed a shared mental model and prioritized situational awareness. Our findings support a need for cognitive aids to

20 CFR 408.355 - Can you withdraw your application?

Science.gov (United States)

2010-04-01

... Section 408.355 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SPECIAL BENEFITS FOR CERTAIN WORLD WAR II VETERANS Filing Applications Withdrawal of Application § 408.355 Can you withdraw your application? (a) Request for withdrawal filed before a determination is made. You may withdraw your application...

Examining the Relationship between Communication Patterns of Source Family and Self-Consciousness with Defensive Styles of Discordant Couples

OpenAIRE

Ma’asoomeh Kheirkhah; Ebrahim Namani

2016-01-01

Research has shown the relationship between communication patterns of source family with defensive styles of discordant couples. For this reason, the present research has examined the relationship between communication patterns of source family and self-consciousness with defensive styles of discordant couples. This study is a descriptive-correlation type. Its population consisted of all discordant couples referred to counseling centers of Mashhad in 2015. Among the referred 140 disc...

Opioid interruptions, pain, and withdrawal symptoms in nursing home residents.

Science.gov (United States)

Redding, Sarah E; Liu, Sophia; Hung, William W; Boockvar, Kenneth S

2014-11-01

Interruptions in opioid use have the potential to cause pain relapse and withdrawal symptoms. The objectives of this study were to observe patterns of opioid interruption during acute illness in nursing home residents and examine associations between interruptions and pain and withdrawal symptoms. Patients from 3 nursing homes in a metropolitan area who were prescribed opioids were assessed for symptoms of pain and withdrawal by researchers blinded to opioid dosage received, using the Brief Pain Inventory Scale and the Clinical Opioid Withdrawal Scale, respectively, during prespecified time periods. The prespecified time periods were 2 weeks after onset of acute illness (eg, urinary tract infection), and 2 weeks after hospital admission and nursing home readmission, if they occurred. Opioid dosing was recorded and a significant interruption was defined as a complete discontinuation or a reduction in dose of >50% for ≥1 day. The covariates age, sex, race, comorbid conditions, initial opioid dose, and initial pain level were recorded. Symptoms pre- and post-opioid interruptions were compared and contrasted with those in a group without opioid interruptions. Sixty-six patients receiving opioids were followed for a mean of 10.9 months and experienced a total of 104 acute illnesses. During 64 (62%) illnesses, patients experienced any reduction in opioid dosing, with a mean (SD) dose reduction of 63.9% (29.9%). During 39 (38%) illnesses, patients experienced a significant opioid interruption. In a multivariable model, residence at 1 of the 3 nursing homes was associated with a lower risk of interruption (odds ratio = 0.073; 95% CI, 0.009 to 0.597; P pain score (difference -0.50 [2.66]; 95% CI, -3.16 to 2.16) and withdrawal score (difference -0.91 [3.12]; 95% CI, -4.03 to 2.21) after the interruption as compared with before interruption. However, when compared with patients without interruptions, patients with interruptions experienced larger increases in pain scores

21 CFR 514.7 - Withdrawal of applications without prejudice.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Withdrawal of applications without prejudice. 514... Withdrawal of applications without prejudice. The sponsor may withdraw his pending application from.... Such withdrawal may be made without prejudice to a future filing. Upon resubmission, the time...

Preferences, constraints or schemas of devotion? Exploring Norwegian mothers' withdrawals from high-commitment careers.

Science.gov (United States)

Halrynjo, Sigtona; Lyng, Selma Therese

2009-06-01

Despite decades of focus on gender equality and work-family balance, parenthood still affects mothers' and fathers' careers differently. Drawing on in-depth interviews with Norwegian mothers who are relinquishing high-commitment careers of law and consultancy, this paper questions the adequacy of established explanations emphasizing constraints vs. individual preferences. Our sample of female professionals living in a well-developed welfare state is particularly apt to explore the processes and mechanisms upholding the statistically gendered pattern of women reducing their work commitment after childbirth. These doubly privileged mothers might be considered to have the best odds for combining career and work commitment with motherhood. Thus, we argue that the approach emphasizing practical constraints does not sufficiently account for the withdrawal from high-commitment careers among these female professionals. Nevertheless, we are not content with the claim of Preference Theory that this shift in commitment is merely a matter of 'not-so-dedicated' women discovering their 'genuine' preferences. Rather, in order to understand why and how this shift occurs, we explore the culturally constructed rationalities and schemas of both work and family devotions. We specifically examine the circumstances, mechanisms and steps in a seemingly individual process of making the shift in commitment from a promising career to a family-friendly job. Moreover, the analysis demonstrates how generous parental leave arrangements designed to enhance gender equality and work-family balance by simply reducing practical constraints may have limited--or even counterproductive--impact within high-commitment occupations where the 'irreplaceability' of workers is taken for granted. Our findings indicate that unless the culturally (re)produced discourses, demands and expectations of both work and family are exposed and challenged, even intentionally gender neutral work-family policies will

Competing effects of groundwater withdrawals and climate change on water availability in semi-arid India

Science.gov (United States)

Sishodia, R. P.; Shukla, S.

2017-12-01

India, a global leader in groundwater use (250 km3/yr), is experiencing groundwater depletion. There has been a 130-fold increase in number of irrigation wells since 1960. Anticipated future increase in groundwater demand is likely to exacerbate the water availability in the semi-arid regions of India. Depending on the direction of change, future climate change may either worsen or enhance the water availability. This study uses an integrated hydrologic modeling approach (MIKE SHE MIKE 11) to compare and combine the effects of future (2040-2069) increased groundwater withdrawals and climate change on surface and groundwater flows and availability for an agricultural watershed in semi-arid south India. Modeling results showed that increased groundwater withdrawals in the future resulted in reduced surface flows (25%) and increased frequency and duration (90 days/yr) of well drying. In contrast, projected future increase in rainfall (7-43%) under the changed climate showed increased groundwater recharge (15-67%) and surface flows (9-155%). Modeling results suggest that the positive effects of climate change may enhance the water availability in this semi-arid region of India. However, in combination with increased withdrawals, climate change was shown to increase the well drying and reduce the water availability especially during dry years. A combination of management options such as flood to drip conversion, energy subsidy reductions and water storage can support increased groundwater irrigated area in the future while mitigating the well drying. A cost-benefit analysis showed that dispersed water storage and flood to drip conversion can be highly cost-effective in this semi-arid region. The study results suggest that the government and management policies need to be focused towards an integrated management of demand and supply to create a sustainable food-water-energy nexus in the region.

Determinants of early withdrawal and of early withdrawal by reason of disability from the Irish labour force in the third age

OpenAIRE

Lawless, Martin

2015-01-01

III – Abstract: Determinants of early withdrawal and early withdrawal by reason of disability from the Irish labour force in the Third Age.Background. This study examines the relationship between early withdrawal and early withdrawal through disability from the Irish labour force in the Third Age. The relationship between unemployment or early retirement and ill health has been determined by a number of studies and, while unemployment through ill health or occupational disability may lead to ...

20 CFR 404.640 - Withdrawal of an application.

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Withdrawal of an application. 404.640 Section 404.640 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Filing of Applications and Other Forms Withdrawal of Application § 404.640 Withdrawal of...

20 CFR 416.355 - Withdrawal of an application.

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Withdrawal of an application. 416.355 Section 416.355 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Filing of Applications Withdrawal of Application § 416.355 Withdrawal of an...

Withdrawal symptoms in internet gaming disorder: A systematic review.

Science.gov (United States)

Kaptsis, Dean; King, Daniel L; Delfabbro, Paul H; Gradisar, Michael

2016-02-01

Internet gaming disorder (IGD) is currently positioned in the appendix of the DSM-5 as a condition requiring further study. The aim of this review was to examine the state of current knowledge of gaming withdrawal symptomatology, given the importance of withdrawal in positioning the disorder as a behavioral addiction. A total of 34 studies, including 10 qualitative studies, 17 research reports on psychometric instruments, and 7 treatment studies, were evaluated. The results indicated that the available evidence on Internet gaming withdrawal is very underdeveloped. Internet gaming withdrawal is most consistently referred to as 'irritability' and 'restlessness' following cessation of the activity. There exists a concerning paucity of qualitative studies that provide detailed clinical descriptions of symptoms arising from cessation of internet gaming. This has arguably compromised efforts to quantify withdrawal symptoms in empirical studies of gaming populations. Treatment studies have not reported on the natural course of withdrawal and/or withdrawal symptom trajectory following intervention. It is concluded that many more qualitative clinical studies are needed, and should be prioritised, to develop our understanding of gaming withdrawal. This should improve clinical descriptions of problematic internet gaming and in turn improve the quantification of IGD withdrawal and thus treatments for harmful internet gaming. Copyright © 2015 Elsevier Ltd. All rights reserved.

Significance and basic patterns of risk communication; Bedeutung und Grundzuege der Risikokommunikation

Energy Technology Data Exchange (ETDEWEB)

Obermeier, O.P. [Gerling Akademie fuer Risikoforschung AG, Muenchen (Germany)]|[Gerling Akademie fuer Risikoforschung AG, Zurich (Switzerland)]|[Augsburg Univ. (Germany)

1996-11-01

The philosophically coloured paper on the aspects of risk communication patterns in society shows that debates about risks are governed by a number of stereotype characters representing the individualist and manager type, bureaucracy and law-and-order type, ego-centered embarrassment activist, and fundamentalist. Every risk-relevant group in the study tries to push forward its own interests. Risk communication is understood as a process of social dealing. (HP) [Deutsch] Die nahezu philosophischen Ueberlegungen zum Thema Risiko belegen, dass alle Risikodiskussionen von den Besitzindividualisten, Buerokraten, Betroffenheitsaktivisten und Fundamentalisten dominiert werden. Jede risikorelevante Gruppierung versucht ihre Gruppenegoismen durchzusetzen. Risikokommunikation wird als Prozess des sozialen Aushandelns aufgefasst. (HP)

Automated pattern analysis in gesture research : similarity measuring in 3D motion capture models of communicative action

NARCIS (Netherlands)

Schueller, D.; Beecks, C.; Hassani, M.; Hinnell, J.; Brenger, B.; Seidl, T.; Mittelberg, I.

2017-01-01

The question of how to model similarity between gestures plays an important role in current studies in the domain of human communication. Most research into recurrent patterns in co-verbal gestures – manual communicative movements emerging spontaneously during conversation – is driven by qualitative

SSRI and SNRI withdrawal symptoms reported on an internet forum.

Science.gov (United States)

Stockmann, Tom; Odegbaro, Dolapo; Timimi, Sami; Moncrieff, Joanna

2018-05-09

Antidepressant withdrawal symptoms are well-recognised, but their potential duration remains uncertain. We aimed to describe the characteristics of withdrawal associated with two popular classes of antidepressants, including duration. We analysed the content of a sample of posts on an antidepressant withdrawal website. We compared the characteristics of withdrawal associated with SSRIs and SNRIs, including time of onset, duration and nature of symptoms. 110 posts about SSRI withdrawal, and 63 concerning SNRI withdrawal, were analysed. The mean duration of withdrawal symptoms was significantly longer with SSRIs than SNRIs: 90.5 weeks (standard deviation, SD, 150.0) and 50.8 weeks (SD 76.0) respectively; p = 0.043). Neurological symptoms, such as 'brain zaps,' were more common among SNRI users (p = 0.023). Psychosexual/genitourinary symptoms may be more common among SSRI users (p = 0.054). The website aims to help people with antidepressant withdrawal, and is therefore likely to attract people who have difficulties. Length of prior use of antidepressants was long, with a mean of 252.2 weeks (SD 250.8). People accessing antidepressant withdrawal websites report experiencing protracted withdrawal symptoms. There are some differences in the characteristics of withdrawal associated with different classes of antidepressants.

The Non-Proliferation Treaty and the Withdrawal Clause

International Nuclear Information System (INIS)

Boutherin, Gregory

2008-01-01

Like any international agreement, the NPT includes a withdrawal clause. The North Korean withdrawal, which was announced in 1993 and became effective in 2003, shows how difficult it is to preserve this possibility, while guaranteeing compliance with signed agreements. To achieve this target, two conditions are required: first, enhancing the means by which the reasons for withdrawals can be made clear and second, to allow the Security Council to draw all the consequences of withdrawals that could imply that a treaty has been violated

The Bursts and Lulls of Multimodal Interaction: Temporal Distributions of Behavior Reveal Differences Between Verbal and Non-Verbal Communication.

Science.gov (United States)

Abney, Drew H; Dale, Rick; Louwerse, Max M; Kello, Christopher T

2018-04-06

Recent studies of naturalistic face-to-face communication have demonstrated coordination patterns such as the temporal matching of verbal and non-verbal behavior, which provides evidence for the proposal that verbal and non-verbal communicative control derives from one system. In this study, we argue that the observed relationship between verbal and non-verbal behaviors depends on the level of analysis. In a reanalysis of a corpus of naturalistic multimodal communication (Louwerse, Dale, Bard, & Jeuniaux, ), we focus on measuring the temporal patterns of specific communicative behaviors in terms of their burstiness. We examined burstiness estimates across different roles of the speaker and different communicative modalities. We observed more burstiness for verbal versus non-verbal channels, and for more versus less informative language subchannels. Using this new method for analyzing temporal patterns in communicative behaviors, we show that there is a complex relationship between verbal and non-verbal channels. We propose a "temporal heterogeneity" hypothesis to explain how the language system adapts to the demands of dialog. Copyright © 2018 Cognitive Science Society, Inc.

Communication Patterns in the Perioperative Environment During Epic Electronic Health Record System Implementation.

Science.gov (United States)

Friend, Tynan H; Jennings, Samantha J; Levine, Wilton C

2017-02-01

In April 2016, Massachusetts General Hospital (MGH) went live with the Epic electronic health records (EHR) system, replacing a variety of EHRs that previously existed in different departments throughout the hospital. At the time of implementation, the Vocera® Badge Communication System, a wireless hands-free communication device distributed to perioperative team members, had increased perioperative communication flow and efficiency. As a quality improvement effort to better understand communication patterns during an EHR go-live, we monitored our Vocera call volume and user volume before, during and after our go-live. We noticed that call volume and user volume significantly increased during our immediate go-live period and quickly returned to baseline levels. We also noticed that call volume increased during periods of unplanned EHR downtime long after our immediate go-live period. When planning the implementation of a new EHR, leadership must plan for and support this critical communication need at the time of the go-live and must also be aware of these needs during unplanned downtime.

Withdrawal-oriented therapy for smokers.

Science.gov (United States)

Hajek, P

1989-06-01

The treatment approach of the Maudsley Hospital Smokers Clinic is described. It stems from the notion that smokers seeking help are dependent on nicotine, and that withdrawal discomfort is a major block to their success in quitting. Accordingly, therapy focuses on helping clients overcome nicotine deprivation. It uses nicotine replacement and a special format of group treatment. Details are given of preparation of clients, use of nicotine chewing gum, use of group-oriented groupwork, use of information about withdrawal, and training in withdrawal-oriented therapy. Data are presented concerning characteristics of the clientele, treatment adherence, and treatment results. A number of controversial issues are addressed, such as the optimal duration of treatment, timing of the quit date, the value of educational input, and the value of individualization of treatment goals.

Demand response in Indian electricity market

International Nuclear Information System (INIS)

Siddiqui, Md Zakaria; Maere d'Aertrycke, Gauthier de; Smeers, Yves

2012-01-01

This paper outlines a methodology for implementing cost of service regulation in retail market for electricity in India when wholesale market is liberalised and operates through an hourly spot market. As in a developing country context political considerations make tariff levels more important than supply security, satisfying the earmarked level of demand takes a back seat. Retail market regulators are often forced by politicians to keep the retail tariff at suboptimal level. This imposes budget constraint on distribution companies to procure electricity that it requires to meet the earmarked level of demand. This is the way demand response is introduced in the system and has its impact on spot market prices. We model such a situation of not being able to serve the earmarked demand as disutility to the regulator which has to be minimised and we compute associated equilibrium. This results in systematic mechanism for cutting loads. We find that even a small cut in ability of the distribution companies to procure electricity from the spot market has profound impact on the prices in the spot market. - Highlights: ► Modelling the impact of retail tariff in different states on spot prices of electricity in India. ► Retail tariffs are usually fixed below appropriate levels by states due to political reasons. ► Due to revenue constraint distribution utility withdraws demand from spot market in peak hours. ► This adversely affects the scarcity rent of generators and subsequently future investment. ► We show possibility of strategic behaviour among state level regulators in setting retail tariff.

Optimised control and pipe burst detection by water demand forecasting

NARCIS (Netherlands)

Bakker, M.

2014-01-01

Water demand forecasting The total water demand in an area is the sum of the water demands of all individual domestic and industrial consumers in that area. These consumers behave in repetitive daily, weekly and annual patterns, and the same repetitive patterns can be observed in the drinking water

Uranium supply and demand

Energy Technology Data Exchange (ETDEWEB)

Spriggs, M J

1976-01-01

Papers were presented on the pattern of uranium production in South Africa; Australian uranium--will it ever become available; North American uranium resources, policies, prospects, and pricing; economic and political environment of the uranium mining industry; alternative sources of uranium supply; whither North American demand for uranium; and uranium demand and security of supply--a consumer's point of view. (LK)

Associations between clinical and sociodemographic data and patterns of communication in pediatric oncology

Directory of Open Access Journals (Sweden)

Marina Kohlsdorf

2016-01-01

Full Text Available Abstract Pediatric communication directly contributes to treatment adherence, fewer symptoms, better clinical responses, healthier treatment adaptation and management of psychosocial issues. This study aimed to evaluate associations between the clinical and sociodemographic data of caregivers and children and the communicative patterns of pediatricians. Three oncohematology physicians and 44 child-caregiver dyads took part, with audio recording of 146 medical consultations. The physicians interacted more often with older children, offering more guidance, clarifying doubts, and asking for information. The number of questions from children and caregivers was positively correlated with the physician’s communicative behaviors. However, there was no association between the age of the children and the number of doubts of the patients. The diagnosis, treatment time, family income, marital status and caregiver’s level of education were associated with the amount of interaction provided by physicians to the children and caregivers. This study offers subsides relevant to psychosocial interventions that may improve communication in pediatric oncohematology settings.

Attending to Communication and Patterns of Interaction: Culturally Sensitive Mental Health Care for Groups of Urban, Ethnically Diverse, Impoverished, and Underserved Women.

Science.gov (United States)

Molewyk Doornbos, Mary; Zandee, Gail Landheer; DeGroot, Joleen

2014-07-01

The United States is ethnically diverse. This diversity presents challenges to nurses, who, without empirical evidence to design culturally congruent interventions, may contribute to mental health care disparities. Using Leininger's theory of culture care diversity and universality, this study documented communication and interaction patterns of ethnically diverse, urban, impoverished, and underserved women. Using a community-based participatory research framework, 61 Black, Hispanic, and White women participated in focus groups around their experiences with anxiety/depression. Researchers recorded verbal communication, nonverbal behavior, and patterns of interaction. The women's communication and interaction patterns gave evidence of three themes that were evident across all focus groups and five subthemes that emerged along ethnic lines. The results suggest cultural universalities and cultural uniquenesses relative to the communication and interaction patterns of urban, ethnically diverse, impoverished, and underserved women that may assist in the design of culturally sensitive mental health care. © The Author(s) 2014.

Water Withdrawals, Use, and Trends in Florida, 2005

Science.gov (United States)

Marella, Richard L.

2009-01-01

In 2005, the total amount of water withdrawals in Florida was estimated at 18,359 million gallons per day (Mgal/d). Saline water accounted for 11,486 Mgal/d (63 percent), and freshwater accounted for 6,873 Mgal/d (37 percent). Groundwater accounted for 4,247 Mgal/d (62 percent) of freshwater withdrawals, and surface water accounted for the remaining 2,626 Mgal/d (38 percent). Surface water accounted for nearly all (99.9 percent) saline-water withdrawals. An additional 660 Mgal/d of reclaimed wastewater was used in Florida during 2005. The largest amount of freshwater was withdrawn from Palm Beach County, and the largest amount of saline water was withdrawn from Pasco County. Fresh groundwater provided drinking water (public supplied and self-supplied) for 16.19 million people (90 percent of Florida's population), and fresh surface water provided drinking water for 1.73 million people (10 percent). The majority of groundwater withdrawals (nearly 60 percent) in 2005 was obtained from the Floridan aquifer system which is present throughout the entire State. The majority of fresh surface-water withdrawals (59 percent) came from the southern Florida hydrologic unit subregion and is associated with Lake Okeechobee and the canals in the Everglades Agricultural Area of Glades, Hendry, and Palm Beach Counties, as well as the Caloosahatchee River and its tributaries in the agricultural areas of Collier, Glades, Hendry, and Lee Counties. Overall, agricultural irrigation accounted for 40 percent of the total freshwater withdrawals (ground and surface), followed by public supply with 37 percent. Public supply accounted for 52 percent of groundwater withdrawals, followed by agricultural self-supplied (31 percent), ommercial-industrial-mining self-supplied (8.5 percent), recreational irrigation and domestic self-supplied (4 percent each), and power generation (0.5 percent). Agricultural self-supplied accounted for 56 percent of fresh surface-water withdrawals, followed by power

Opiate Withdrawal Complicated by Tetany and Cardiac Arrest

Directory of Open Access Journals (Sweden)

Irfanali R. Kugasia

2014-01-01

Full Text Available Patients with symptoms of opiate withdrawal, after the administration of opiate antagonist by paramedics, are a common presentation in the emergency department of hospitals. Though most of opiate withdrawal symptoms are benign, rarely they can become life threatening. This case highlights how a benign opiate withdrawal symptom of hyperventilation led to severe respiratory alkalosis that degenerated into tetany and cardiac arrest. Though this patient was successfully resuscitated, it is imperative that severe withdrawal symptoms are timely identified and immediate steps are taken to prevent catastrophes. An easier way to reverse the severe opiate withdrawal symptom would be with either low dose methadone or partial opiate agonists like buprenorphine. However, if severe acid-base disorder is identified, it would be safer to electively intubate these patients for better control of their respiratory and acid-base status.

The alcohol withdrawal syndrome.

LENUS (Irish Health Repository)

McKeon, A

2008-08-01

The alcohol withdrawal syndrome (AWS) is a common management problem in hospital practice for neurologists, psychiatrists and general physicians alike. Although some patients have mild symptoms and may even be managed in the outpatient setting, others have more severe symptoms or a history of adverse outcomes that requires close inpatient supervision and benzodiazepine therapy. Many patients with AWS have multiple management issues (withdrawal symptoms, delirium tremens, the Wernicke-Korsakoff syndrome, seizures, depression, polysubstance abuse, electrolyte disturbances and liver disease), which requires a coordinated, multidisciplinary approach. Although AWS may be complex, careful evaluation and available treatments should ensure safe detoxification for most patients.

42 CFR 457.170 - Withdrawal process.

Science.gov (United States)

2010-10-01

... 42 Public Health 4 2010-10-01 2010-10-01 false Withdrawal process. 457.170 Section 457.170 Public... Plans for Child Health Insurance Programs and Outreach Strategies § 457.170 Withdrawal process. (a... amendment, or any portion of a proposed State plan or plan amendment, at any time during the review process...

Effect of Morphine Withdrawal Syndrome on Cerebral Ischemia

Directory of Open Access Journals (Sweden)

Mohammad Allahtavakoli

2011-01-01

Full Text Available Objective(sOpioid abuse is still remained a major mental health problem, a criminal legal issue and may cause ischemic brain changes including stroke and brain edema. In the present study, we investigated whether spontaneously withdrawal syndrome might affect stroke outcomes.Materials and MethodsAddiction was induced by progressive incremental doses of morphine over 7 days. Behavioral signs of withdrawal were observed 24, 48 and 72 hr after morphine deprivation and total withdrawal score was determined. Cerebral ischemia was induced 18-22 hr after the last morphine injection by placing a natural clot into the middle cerebral artery (MCA. Neurological deficits were evaluated at 2, 24 and 48 hr after ischemia induction, and infarct size and brain edema were determined at 48 hr after stroke.ResultsMorphine withdrawal animals showed a significant increase in total withdrawal score and decrease of weight gain during the 72 hr after the last morphine injection. Compared to the addicted and control animals, infarct volume and brain edema were significantly increased in the morphine deprived animals (P< 0.05 at 48 hr after cerebral ischemia. Also, neurological deficits were higher in the morphine-withdrawn rats at 48 hr after stroke (P< 0.05. ConclusionOur data indicates that spontaneous withdrawal syndrome may worsen stroke outcomes. Further investigations are necessary to elucidate mechanisms of opiate withdrawal syndrome on stroke.

Mitragynine attenuates withdrawal syndrome in morphine-withdrawn zebrafish.

Directory of Open Access Journals (Sweden)

Beng-Siang Khor

Full Text Available A major obstacle in treating drug addiction is the severity of opiate withdrawal syndrome, which can lead to unwanted relapse. Mitragynine is the major alkaloid compound found in leaves of Mitragyna speciosa, a plant widely used by opiate addicts to mitigate the harshness of drug withdrawal. A series of experiments was conducted to investigate the effect of mitragynine on anxiety behavior, cortisol level and expression of stress pathway related genes in zebrafish undergoing morphine withdrawal phase. Adult zebrafish were subjected to two weeks chronic morphine exposure at 1.5 mg/L, followed by withdrawal for 24 hours prior to tests. Using the novel tank diving tests, we first showed that morphine-withdrawn zebrafish display anxiety-related swimming behaviors such as decreased exploratory behavior and increased erratic movement. Morphine withdrawal also elevated whole-body cortisol levels, which confirms the phenotypic stress-like behaviors. Exposing morphine-withdrawn fish to mitragynine however attenuates majority of the stress-related swimming behaviors and concomitantly lower whole-body cortisol level. Using real-time PCR gene expression analysis, we also showed that mitragynine reduces the mRNA expression of corticotropin releasing factor receptors and prodynorphin in zebrafish brain during morphine withdrawal phase, revealing for the first time a possible link between mitragynine's ability to attenuate anxiety during opiate withdrawal with the stress-related corticotropin pathway.

Modeling and clustering water demand patterns from real-world smart meter data

Directory of Open Access Journals (Sweden)

N. Cheifetz

2017-08-01

Full Text Available Nowadays, drinking water utilities need an acute comprehension of the water demand on their distribution network, in order to efficiently operate the optimization of resources, manage billing and propose new customer services. With the emergence of smart grids, based on automated meter reading (AMR, a better understanding of the consumption modes is now accessible for smart cities with more granularities. In this context, this paper evaluates a novel methodology for identifying relevant usage profiles from the water consumption data produced by smart meters. The methodology is fully data-driven using the consumption time series which are seen as functions or curves observed with an hourly time step. First, a Fourier-based additive time series decomposition model is introduced to extract seasonal patterns from time series. These patterns are intended to represent the customer habits in terms of water consumption. Two functional clustering approaches are then used to classify the extracted seasonal patterns: the functional version of K-means, and the Fourier REgression Mixture (FReMix model. The K-means approach produces a hard segmentation and K representative prototypes. On the other hand, the FReMix is a generative model and also produces K profiles as well as a soft segmentation based on the posterior probabilities. The proposed approach is applied to a smart grid deployed on the largest water distribution network (WDN in France. The two clustering strategies are evaluated and compared. Finally, a realistic interpretation of the consumption habits is given for each cluster. The extensive experiments and the qualitative interpretation of the resulting clusters allow one to highlight the effectiveness of the proposed methodology.

Modeling and clustering water demand patterns from real-world smart meter data

Science.gov (United States)

Cheifetz, Nicolas; Noumir, Zineb; Samé, Allou; Sandraz, Anne-Claire; Féliers, Cédric; Heim, Véronique

2017-08-01

Nowadays, drinking water utilities need an acute comprehension of the water demand on their distribution network, in order to efficiently operate the optimization of resources, manage billing and propose new customer services. With the emergence of smart grids, based on automated meter reading (AMR), a better understanding of the consumption modes is now accessible for smart cities with more granularities. In this context, this paper evaluates a novel methodology for identifying relevant usage profiles from the water consumption data produced by smart meters. The methodology is fully data-driven using the consumption time series which are seen as functions or curves observed with an hourly time step. First, a Fourier-based additive time series decomposition model is introduced to extract seasonal patterns from time series. These patterns are intended to represent the customer habits in terms of water consumption. Two functional clustering approaches are then used to classify the extracted seasonal patterns: the functional version of K-means, and the Fourier REgression Mixture (FReMix) model. The K-means approach produces a hard segmentation and K representative prototypes. On the other hand, the FReMix is a generative model and also produces K profiles as well as a soft segmentation based on the posterior probabilities. The proposed approach is applied to a smart grid deployed on the largest water distribution network (WDN) in France. The two clustering strategies are evaluated and compared. Finally, a realistic interpretation of the consumption habits is given for each cluster. The extensive experiments and the qualitative interpretation of the resulting clusters allow one to highlight the effectiveness of the proposed methodology.

Asian oil demand

International Nuclear Information System (INIS)

Fesharaki, F.

2005-01-01

This conference presentation examined global oil market development and the role of Asian demand. It discussed plateau change versus cyclical movement in the global oil market; supply and demand issues of OPEC and non-OPEC oil; if high oil prices reduce demand; and the Asian oil picture in the global context. Asian oil demand has accounted for about 50 per cent of the global incremental oil market growth. The presentation provided data charts in graphical format on global and Asia-Pacific incremental oil demand from 1990-2005; Asia oil demand growth for selected nations; real GDP growth in selected Asian countries; and, Asia-Pacific oil production and net import requirements. It also included charts in petroleum product demand for Asia-Pacific, China, India, Japan, and South Korea. Other data charts included key indicators for China's petroleum sector; China crude production and net oil import requirements; China's imports and the share of the Middle East; China's oil exports and imports; China's crude imports by source for 2004; China's imports of main oil products for 2004; India's refining capacity; India's product balance for net-imports and net-exports; and India's trade pattern of oil products. tabs., figs

Laser-induced superhydrophobic grid patterns on PDMS for droplet arrays formation

Energy Technology Data Exchange (ETDEWEB)

Farshchian, Bahador [Ingram School of Engineering, Texas State University, San Marcos, TX 78666 (United States); Gatabi, Javad R. [Materials Science, Engineering and Commercialization, Texas State University, San Marcos, TX 78666 (United States); Bernick, Steven M.; Park, Sooyeon [Ingram School of Engineering, Texas State University, San Marcos, TX 78666 (United States); Lee, Gwan-Hyoung [Department of Materials Science and Engineering, Yonsei University, Seoul 03722 (Korea, Republic of); Droopad, Ravindranath [Ingram School of Engineering, Texas State University, San Marcos, TX 78666 (United States); Materials Science, Engineering and Commercialization, Texas State University, San Marcos, TX 78666 (United States); Kim, Namwon, E-mail: n_k43@txstate.edu [Ingram School of Engineering, Texas State University, San Marcos, TX 78666 (United States)

2017-02-28

Highlights: • Superhydrophobic grid patterns were processed on the surface of PDMS using a pulsed nanosecond laser. • Droplet arrays form instantly on the laser-patterned PDMS with the superhydrophobic grid pattern when the PDMS sample is simply immersed in and withdrawn from water. • Droplet size can be controlled by controlling the pitch size of superhydrophobic grid and the withdrawal speed. - Abstract: We demonstrate a facile single step laser treatment process to render a polydimethylsiloxane (PDMS) surface superhydrophobic. By synchronizing a pulsed nanosecond laser source with a motorized stage, superhydrophobic grid patterns were written on the surface of PDMS. Hierarchical micro and nanostructures were formed in the irradiated areas while non-irradiated areas were covered by nanostructures due to deposition of ablated particles. Arrays of droplets form spontaneously on the laser-patterned PDMS with superhydrophobic grid pattern when the PDMS sample is simply immersed in and withdrawn from water due to different wetting properties of the irradiated and non-irradiated areas. The effects of withdrawal speed and pitch size of superhydrophobic grid on the size of formed droplets were investigated experimentally. The droplet size increases initially with increasing the withdrawal speed and then does not change significantly beyond certain points. Moreover, larger droplets are formed by increasing the pitch size of the superhydrophobic grid. The droplet arrays formed on the laser-patterned PDMS with wettability contrast can be used potentially for patterning of particles, chemicals, and bio-molecules and also for cell screening applications.

Information and communication technology demands at work: the association with job strain, effort-reward imbalance and self-rated health in different socio-economic strata.

Science.gov (United States)

Stadin, Magdalena; Nordin, Maria; Broström, Anders; Magnusson Hanson, Linda L; Westerlund, Hugo; Fransson, Eleonor I

2016-10-01

The use of information and communication technology (ICT) is common in modern working life. ICT demands may give rise to experience of work-related stress. Knowledge about ICT demands in relation to other types of work-related stress and to self-rated health is limited. Consequently, the aim of this study was to examine the association between ICT demands and two types of work-related stress [job strain and effort-reward imbalance (ERI)] and to evaluate the association between these work-related stress measures and self-rated health, in general and in different SES strata. This study is based on cross-sectional data from the Swedish Longitudinal Occupational Survey of Health collected in 2014, from 14,873 gainfully employed people. ICT demands, job strain, ERI and self-rated health were analysed as the main measures. Sex, age, SES, lifestyle factors and BMI were used as covariates. ICT demands correlated significantly with the dimensions of the job strain and ERI models, especially with the demands (r = 0.42; p work-related stress in modern working life.

Getting to the Heart of Masculinity Stressors: Masculinity Threats Induce Pronounced Vagal Withdrawal During a Speaking Task.

Science.gov (United States)

Kramer, Brandon L; Himmelstein, Mary S; Springer, Kristen W

2017-12-01

Previous work has found that traditional masculinity ideals and behaviors play a crucial role in higher rates of morbidity and mortality for men. Some studies also suggest that threatening men's masculinity can be stressful. Over time, this stress can weigh on men's cardiovascular and metabolic systems, which may contribute to men's higher rates of cardiometabolic health issues. The purpose of this study is to explore how masculinity threats affect men's heart rate and heart rate variability reactivity (i.e., vagal withdrawal) to masculinity feedback on a social speaking task. Two hundred and eighty-five undergraduate males were randomly assigned to one of six conditions during a laboratory-based speech task. They received one of two feedback types (masculinity or control) and one of three feedback levels (low, high, or dropping) in order to assess whether masculinity threats influence heart rate reactivity and vagal withdrawal patterns during the speech task. Men who receive low masculinity feedback during the speech task experienced more pronounced vagal withdrawal relative to those who received the control. Masculinity threats can induce vagal withdrawal that may accumulate over the life course to contribute to men's relatively worse cardiometabolic health.

Withdrawing to a Virtual World: Associations between Subtypes of Withdrawal, Media Use, and Maladjustment in Emerging Adults

Science.gov (United States)

Nelson, Larry J.; Coyne, Sarah M.; Howard, Emily; Clifford, Brandon N.

2016-01-01

An approach-avoidance model of social withdrawal (Asendorpf, 1990) identifies 3 types of social withdrawal including shyness, unsociability, and avoidance. Each appears to be uniquely associated with varying indicators of maladjustment in emerging adulthood (Nelson, 2013) but little, if any, work has been done to see how they might be linked to…

An overview of research on social withdrawal in childhood

OpenAIRE

野村, あすか; NOMURA, Asuka

2013-01-01

In recent years, “HIKIKOMORI” in adolescence or adulthood has grown into a serious problem in Japan and the need for early intervention and support has been emphasized. Among the risk factors of “HIKIKOMORI” is social withdrawal in childhood. With this in mind, I reviewed previous studies on the social withdrawal in children living abroad. The review commences with an examination of definitions of social withdrawal, which showed that in some foreign countries, social withdrawal refers to the ...

Why withdrawal from the European Union is undemocratic

DEFF Research Database (Denmark)

Olsen, Tore Vincents; Rostbøll, Christian F.

2017-01-01

The Lisbon Treaty from 2009 introduced the possibility for individual member states to withdraw from the European Union (EU) on the basis of a unilateral decision. In June 2016 the UK decided to leave the EU invoking article 50 of the treaty. But is withdrawal democratically legitimate? In fact......, the all affected principle suggests that it is undemocratic for subunits to leave larger political units when it adversely affects other citizens without including them in the decision. However, it is unclear what the currency of this affectedness is and, hence, why withdrawal would be undemocratic. We...... argue that it is the effect of withdrawal on the status of citizens as free and equal that is decisive and that explains why unilateral withdrawal of subunits from larger units is democratically illegitimate. Moreover, on the ‘all affected status principle’ that we develop, even multilaterally agreed...

Development of life cycle water-demand coefficients for coal-based power generation technologies

International Nuclear Information System (INIS)

Ali, Babkir; Kumar, Amit

2015-01-01

Highlights: • We develop water consumption and withdrawals coefficients for coal power generation. • We develop life cycle water footprints for 36 coal-based electricity generation pathways. • Different coal power generation technologies were assessed. • Sensitivity analysis of plant performance and coal transportation on water demand. - Abstract: This paper aims to develop benchmark coefficients for water consumption and water withdrawals over the full life cycle of coal-based power generation. This study considered not only all of the unit operations involved in the full electricity generation life cycle but also compared different coal-based power generating technologies. Overall this study develops the life cycle water footprint for 36 different coal-based electricity generation pathways. Power generation pathways involving new technologies of integrated gasification combined cycle (IGCC) or ultra supercritical technology with coal transportation by conventional means and using dry cooling systems have the least complete life cycle water-demand coefficients of about 1 L/kW h. Sensitivity analysis is conducted to study the impact of power plant performance and coal transportation on the water demand coefficients. The consumption coefficient over life cycle of ultra supercritical or IGCC power plants are 0.12 L/kW h higher when conventional transportation of coal is replaced by coal-log pipeline. Similarly, if the conventional transportation of coal is replaced by its transportation in the form of a slurry through a pipeline, the consumption coefficient of a subcritical power plant increases by 0.52 L/kW h

DISCOVERING AND LABELLING OF TEMPORAL GRANULARITY PATTERNS IN ELECTRIC POWER DEMAND WITH A BRAZILIAN CASE STUDY

Directory of Open Access Journals (Sweden)

Gabriela Servidone

Full Text Available ABSTRACT Clustering is commonly used to group data in order to represent the behaviour of a system as accurately as possible by obtaining patterns and profiles. In this paper, clustering is applied with partitioning-clustering techniques, specifically, Partitioning around Medoids (PAM to analyse load curves from a city of South-eastern Brazil in São Paulo state. A top-down approach in time granularity is performed to detect and to label profiles which could be affected by seasonal trends and daily/hourly time blocks. Time-granularity patterns are useful to support the improvement of activities related to distribution, transmission and scheduling of energy supply. Results indicated four main patterns which were post-processed in hourly blocks by using shades of grey to help final-user to understand demand thresholds according to the meaning of dark grey, light grey and white colours. A particular and different behaviour of load curve was identified for the studied city if it is compared to the classical behaviour of urban cities.

How physician electronic health record screen sharing affects patient and doctor non-verbal communication in primary care.

Science.gov (United States)

Asan, Onur; Young, Henry N; Chewning, Betty; Montague, Enid

2015-03-01

Use of electronic health records (EHRs) in primary-care exam rooms changes the dynamics of patient-physician interaction. This study examines and compares doctor-patient non-verbal communication (eye-gaze patterns) during primary care encounters for three different screen/information sharing groups: (1) active information sharing, (2) passive information sharing, and (3) technology withdrawal. Researchers video recorded 100 primary-care visits and coded the direction and duration of doctor and patient gaze. Descriptive statistics compared the length of gaze patterns as a percentage of visit length. Lag sequential analysis determined whether physician eye-gaze influenced patient eye gaze, and vice versa, and examined variations across groups. Significant differences were found in duration of gaze across groups. Lag sequential analysis found significant associations between several gaze patterns. Some, such as DGP-PGD ("doctor gaze patient" followed by "patient gaze doctor") were significant for all groups. Others, such DGT-PGU ("doctor gaze technology" followed by "patient gaze unknown") were unique to one group. Some technology use styles (active information sharing) seem to create more patient engagement, while others (passive information sharing) lead to patient disengagement. Doctors can engage patients in communication by using EHRs in the visits. EHR training and design should facilitate this. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

15 CFR 10.13 - Withdrawal of a published standard.

Science.gov (United States)

2010-01-01

...) Before withdrawing a standard published under these procedures, the Director will review the relative... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Withdrawal of a published standard. 10... DEVELOPMENT OF VOLUNTARY PRODUCT STANDARDS § 10.13 Withdrawal of a published standard. (a) Standards published...

75 FR 7526 - Withdrawal of Regulatory Guide

Science.gov (United States)

2010-02-19

...'s Electronic Reading Room at http://www.nrc.gov/reading-rm/doc-collections . Regulatory guides are... NUCLEAR REGULATORY COMMISSION [NRC-2010-0052] Withdrawal of Regulatory Guide AGENCY: Nuclear Regulatory Commission. ACTION: Withdrawal of Regulatory Guide 1.56, ``Maintenance of Water Purity in Boiling...

Acupuncture for alcohol withdrawal: a randomized controlled trial.

Science.gov (United States)

Trümpler, François; Oez, Suzan; Stähli, Peter; Brenner, Hans Dieter; Jüni, Peter

2003-01-01

Previous trials on acupuncture in alcohol addiction were in outpatients and focused on relapse prevention. Rates of dropout were high and interpretation of results difficult. We compared auricular laser and needle acupuncture with sham laser stimulation in reducing the duration of alcohol withdrawal. Inpatients undergoing alcohol withdrawal were randomly allocated to laser acupuncture (n = 17), needle acupuncture (n = 15) or sham laser stimulation (n = 16). Attempts were made to blind patients, therapists and outcome assessors, but this was not feasible for needle acupuncture. The duration of withdrawal symptoms (as assessed using a nurse-rated scale) was the primary outcome; the duration of sedative prescription was the secondary outcome. Patients randomized to laser and sham laser had identical withdrawal symptom durations (median 4 days). Patients randomized to needle stimulation had a shorter duration of withdrawal symptoms (median 3 days; P = 0.019 versus sham intervention), and tended to have a shorter duration of sedative use, but these differences diminished after adjustment for baseline differences. The data from this pilot trial do not suggest a relevant benefit of auricular laser acupuncture for alcohol withdrawal. A larger trial including adequate sham interventions is needed, however, to reliably determine the effectiveness of any type of auricular acupuncture in this condition.

45 CFR 400.301 - Withdrawal from the refugee program.

Science.gov (United States)

2010-10-01

... 45 Public Welfare 2 2010-10-01 2010-10-01 false Withdrawal from the refugee program. 400.301... Waivers and Withdrawals § 400.301 Withdrawal from the refugee program. (a) In the event that a State... assistance, social services, preventive health, and an unaccompanied minors program if appropriate. A State...

Digitizing Patterns of Power - Cartographic Communication for Digital Humanities

Science.gov (United States)

Kriz, Karel; Pucher, Alexander; Breier, Markus

2018-05-01

The representation of space in medieval texts, the appropriation of land and the subsequent installation of new structures of power are central research topics of the project "Digitizing Patterns of Power" (DPP). The project focuses on three regional case studies: the Eastern Alps and the Morava-Thaya region, the historical region of Macedonia, and historical Southern Armenia. DPP is a multidisciplinary project, conducted by the Austrian Academy of Sciences the Institute for Medieval Research (IMAFO) in cooperation with the University of Vienna, Department of Geography and Regional Research. It is part of an initiative to promote digital humanities research in Austria. DPP brings together expertise from historical and archaeological research as well as cartography and geocommunication to explore medieval geographies. The communication of space, time and spatial interconnectivity is an essential aspect of DPP. By incorporating digital cartographic expertise, relevant facts can be depicted in a more effective visual form. Optimal cartographic visualization of base data as well as the historical and archaeological information in an interactive map-based online platform are important features. However, the multidisciplinary of the project presents the participants with various challenges. The different involved disciplines, among them cartography, archaeology and history each have their own approaches to relevant aspects of geography and geocommunication. This paper treats geocommunication characteristics and approaches to interactive mapping in a historical and archaeological context within a multidisciplinary project environment. The fundamental challenges of cartographic communication within DPP will be presented. Furthermore, recent results on the communication of historical topographic, as well as uncertain thematic content will be demonstrated.

Effect of Potassium Channel Modulators on Morphine Withdrawal in Mice

Directory of Open Access Journals (Sweden)

Vikas Seth

2010-01-01

Full Text Available The present study was conducted to investigate the effect of potassium channel openers and blockers on morphine withdrawal syndrome. Mice were rendered dependent on morphine by subcutaneous injection of morphine; four hours later, withdrawal was induced by using an opioid antagonist, naloxone. Mice were observed for 30 minutes for the withdrawal signs ie, the characteristic jumping, hyperactivity, urination and diarrhea. ATP-dependent potassium (K + ATP channel modulators were injected intraperitoneally (i.p. 30 minutes before the naloxone. It was found that a K + ATP channel opener, minoxidil (12.5–50 mg/kg i.p., suppressed the morphine withdrawal significantly. On the other hand, the K + ATP channel blocker glibenclamide (12.5–50 mg/kg i.p. caused a significant facilitation of the withdrawal. Glibenclamide was also found to abolish the minoxidil's inhibitory effect on morphine withdrawal. The study concludes that K + ATP channels play an important role in the genesis of morphine withdrawal and K + ATP channel openers could be useful in the management of opioid withdrawal. As morphine opens K + ATP channels in neurons, the channel openers possibly act by mimicking the effects of morphine on neuronal K + currents.

Resource Demand Scenarios for the Major Metals.

Science.gov (United States)

Elshkaki, Ayman; Graedel, T E; Ciacci, Luca; Reck, Barbara K

2018-03-06

The growth in metal use in the past few decades raises concern that supplies may be insufficient to meet demands in the future. From the perspective of historical and current use data for seven major metals-iron, manganese, aluminum, copper, nickel, zinc, and lead-we have generated several scenarios of potential metal demand from 2010 to 2050 under alternative patterns of global development. We have also compared those demands with various assessments of potential supply to midcentury. Five conclusions emerge: (1) The calculated demand for each of the seven metals doubles or triples relative to 2010 levels by midcentury; (2) The largest demand increases relate to a scenario in which increasingly equitable values and institutions prevail throughout the world; (3) The metal recycling flows in the scenarios meet only a modest fraction of future metals demand for the next few decades; (4) In the case of copper, zinc, and perhaps lead, supply may be unlikely to meet demand by about midcentury under the current use patterns of the respective metals; (5) Increased rates of demand for metals imply substantial new energy provisioning, leading to increases in overall global energy demand of 21-37%. These results imply that extensive technological transformations and governmental initiatives could be needed over the next several decades in order that regional and global development and associated metal demand are not to be constrained by limited metal supply.

Differential associations between sensory response patterns and language, social, and communication measures in children with autism or other developmental disabilities.

Science.gov (United States)

Watson, Linda R; Patten, Elena; Baranek, Grace T; Poe, Michele; Boyd, Brian A; Freuler, Ashley; Lorenzi, Jill

2011-12-01

To examine patterns of sensory responsiveness (i.e., hyperresponsiveness, hyporesponsiveness, and sensory seeking) as factors that may account for variability in social-communicative symptoms of autism and variability in language, social, and communication skill development in children with autism or other developmental disabilities (DDs). Children with autistic disorder (AD; n = 72, mean age = 52.3 months) and other DDs (n = 44, mean age = 48.1 months) participated in a protocol measuring sensory response patterns; social-communicative symptoms of autism; and language, social, and communication skills. Hyporesponsiveness was positively associated with social-communicative symptom severity, with no significant group difference in the association. Hyperresponsiveness was not significantly associated with social-communicative symptom severity. A group difference emerged for sensory seeking and social-communicative symptom severity, with a positive association for the AD group only. For the 2 groups of children combined, hyporesponsiveness was negatively associated with language skills and social adaptive skills. Sensory seeking also was negatively associated with language skills. These associations did not differ between the 2 groups. Aberrant sensory processing may play an important role in the pathogenesis of autism and other DDs as well as in the rate of acquisition of language, social, and communication skills.

Decomposing issue patterns in crisis communication : the case of the lost airliner

OpenAIRE

Zhang, Boyang; Vos, Marita; Veijalainen, Jari

2018-01-01

This research explores the relation between a crisis and public discussion on related issues. In organisational crisis communication, a singleissue strategy is often proposed. Such a strategy, however, may not be adequate in more complex crises where the crisis lifecycle is likely to encompass shorter lifecycles of issues that generate media attention. Decomposing the online crisis debate into a pattern of issues supports understanding of public perceptions, and hence of cri...

Water withdrawals, use, and trends in Florida, 2010

Science.gov (United States)

Marella, Richard L.

2014-01-01

In 2010, the total amount of water withdrawn in Florida was estimated to be 14,988 million gallons per day (Mgal/d). Saline water accounted for 8,589 Mgal/d (57 percent) and freshwater accounted for 6,399 Mgal/d (43 percent). Groundwater accounted for 4,166 Mgal/d (65 percent) of freshwater withdrawals, and surface water accounted for the remaining 2,233 Mgal/d (35 percent). Surface water accounted for nearly all (99.9 percent) saline-water withdrawals. An additional 659 Mgal/d of reclaimed wastewater was used in Florida during 2010. Freshwater withdrawals were greatest in Palm Beach County (707 Mgal/d), and saline-water withdrawals were greatest in Hillsborough County (1,715 Mgal/d). Fresh groundwater provided drinking water (public supplied and self-supplied) for 17.33 million people (92 percent of Florida’s population), and fresh surface water provided drinking water for 1.47 million people (8 percent). The statewide public-supply gross per capita use for 2010 was 134 gallons per day, whereas the statewide public-supply domestic per capita use was 85 gallons per day. The majority of groundwater withdrawals (almost 62 percent) in 2010 were obtained from the Floridan aquifer system, which is present throughout most of the State. The majority of fresh surface-water withdrawals (56 percent) came from the southern Florida hydrologic unit subregion and is associated with Lake Okeechobee and the canals in the Everglades Agricultural Area of Glades, Hendry, and Palm Beach Counties, as well as the Caloosahatchee River and its tributaries in the agricultural areas of Collier, Glades, Hendry, and Lee Counties. Overall, agricultural irrigation accounted for 40 percent of the total freshwater withdrawals (ground and surface), followed by public supply with 35 percent. Public supply accounted for 48 percent of groundwater withdrawals, followed by agricultural self-supplied (34 percent), commercial-industrial-mining self-supplied (7 percent), recreational

A psychometric validation of the Short Alcohol Withdrawal Scale (SAWS)

DEFF Research Database (Denmark)

Elholm, Bjarne; Larsen, Klaus; Hornnes, Nete

2010-01-01

The study aimed to evaluate psychometrically a Danish translation of the Short Alcohol Withdrawal Scale (SAWS) in an outpatient setting in patients with Alcohol Dependence (AD) and Alcohol Withdrawal Symptoms/Syndrome (AWS).......The study aimed to evaluate psychometrically a Danish translation of the Short Alcohol Withdrawal Scale (SAWS) in an outpatient setting in patients with Alcohol Dependence (AD) and Alcohol Withdrawal Symptoms/Syndrome (AWS)....

[The effect of palonosetron on rocuronium-induced withdrawal movement].

Science.gov (United States)

Park, Ki-Bum; Jeon, Younghoon; Yi, Junggu; Kim, Ji-Hyun; Chung, Seung-Yeon; Kwak, Kyung-Hwa

Rocuronium causes pain and withdrawal movement during induction of anesthesia. In this study, palonosetron was investigated to have analgesic effect on the reduction of rocuronium-induced withdrawal movement. 120 patients were randomly assigned to one of three groups to receive either saline, lidocaine 20mg, or palonosetron 0.075mg with a tourniquet applied two minutes before thiopental sodium (5mg.kg -1 ) was given intravenously. After loss of consciousness, rocuronium (0.6mg.kg -1 ) was injected and the withdrawal movement was estimated by 4-point scale in a double-blind manner. The overall incidence of rocuronium withdrawal movement was 50% with lidocaine (p=0.038), 38% with palonosetron (p=0.006) compared with 75% for saline. The incidence of no pain to mild pain was significantly lower in the lidocaine and palonosetron groups (85% and 92% respectively) than in the saline group (58%). However, there was no significant difference in withdrawal movement between the lidocaine and palonosetron groups. There was no severe movement with palonosetron. Pretreatment of palonosetron with venous occlusion may attenuate rocuronium-induced withdrawal movement as effective as the use of lidocaine. It suggested that peripheral action of palonosetron was effective to reduce rocuronium-induced withdrawal movement. Copyright © 2016. Publicado por Elsevier Editora Ltda.

[Treatment of gamma-hydroxybutyrate withdrawal].

Science.gov (United States)

Strand, Niels August Willer; Petersen, Tonny Studsgaard; Nielsen, Lars Martin; Boegevig, Soren

2017-12-11

Gamma-hydroxybutyrate (GHB) is a drug of abuse, for which physical addiction develops quickly. GHB withdrawal can develop into a life-threatening condition and has previously been treated mainly with benzodiazepines. These have not always proven effective, leading to long hospitalizations in intensive care units. Based on successful Dutch treatment results for using GHB to treat GHB withdrawal symptoms, we propose to implement a similar method in Denmark. The method requires an interdisciplinary effort for which The Danish Poison Information Centre should be consulted for expertise.

21 CFR 171.7 - Withdrawal of petition without prejudice.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Withdrawal of petition without prejudice. 171.7... Withdrawal of petition without prejudice. (a) In some cases the Commissioner will notify the petitioner that... clarification or the obtaining of additional data. This withdrawal will be without prejudice to a future filing...

21 CFR 571.7 - Withdrawal of petition without prejudice.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Withdrawal of petition without prejudice. 571.7... Withdrawal of petition without prejudice. (a) In some cases the Commissioner will notify the petitioner that... clarification or the obtaining of additional data. This withdrawal will be without prejudice to a future filing...

Creating a perfect storm to increase consumer demand for Wisconsin's Tobacco Quitline.

Science.gov (United States)

Sheffer, Megan A; Redmond, Lezli A; Kobinsky, Kate H; Keller, Paula A; McAfee, Tim; Fiore, Michael C

2010-03-01

Telephone quitlines are a clinically proven and cost-effective population-wide tobacco-dependence treatment, and this option is now available in all 50 states. Yet, only 1% of the smoking population accesses these services annually. This report describes a series of policy, programmatic, and communication initiatives recently implemented in Wisconsin that resulted in a dramatic increase in consumer demand for the Wisconsin Tobacco Quitline (WTQL). In 2007, the Wisconsin legislature voted to increase the state cigarette excise tax rate by $1.00, from $0.77/pack to $1.77/pack effective January 1, 2008. In preparation for the tax increase, the Wisconsin Tobacco Prevention and Control Program, the University of Wisconsin Center for Tobacco Research and Intervention, which manages the WTQL, and the state's quitline service provider, Free & Clear, Inc., collaborated to enhance quitline knowledge, availability, and services with the goal of increasing consumer demand for services. The enhancements included for the first time, a free 2-week supply of over-the-counter nicotine replacement medication for tobacco users who agreed to receive multi-session quitline counseling. A successful statewide earned media campaign intensified the impact of these activities, which were timed to coincide with temporal smoking-cessation behavioral patterns (i.e., New Year's resolutions). As a result, the WTQL fielded a record 27,000 calls during the first 3 months of 2008, reaching nearly 3% of adult Wisconsin smokers. This experience demonstrates that consumer demand for quitline services can be markedly enhanced through policy and communication initiatives to increase the population reach of this evidence-based treatment. Published by Elsevier Inc.

Distinct effects of protracted withdrawal on affect, craving, selective attention and executive functions among alcohol-dependent patients.

Science.gov (United States)

Cordovil De Sousa Uva, Mariana; Luminet, Olivier; Cortesi, Marie; Constant, Eric; Derely, Marc; De Timary, Philippe

2010-01-01

The present study examined the effects of protracted alcohol withdrawal on affectivity, craving, selective attention and executive functions (EFs) in alcohol-dependent patients. Selective attention (The D2 Cancellation Test), flexibility (Trail Making Test), inhibition (Stroop Task), decision making (Iowa Gambling Task), craving (Obsessive-Compulsive Drinking Scale) and state affectivity (Positive and Negative Affectivity Schedule) were assessed in alcohol-dependent patients (DSM-IV, n = 35) matched to non-alcohol-dependent participants (n = 22) at the onset (T1: day 1 or 2) and at the end (T2: days 14-18) of protracted withdrawal during rehab. Alcohol-dependent patients' abilities to focus their attention on relevant information, to switch from one pattern to another, to inhibit irrelevant information and to make advantageous choices were lower than those of control participants during both times of a withdrawal cure. No effect of time emerged from analyses for selective attention and EF deficits. Conversely, significant differences between T1 and T2 were observed for craving and affect scores indicating a weakening of alcohol craving and negative affect as well as an improvement of positive affect among patients from onset to the end of cure. Control functions of the Supervisory Attentional System (Norman and Shallice, 1986) were impaired and did not improve during a 3-week withdrawal cure, whereas alcohol craving and negative state affectivity significantly improved in parallel during this period. Implications for understanding the clinical processes of withdrawal are discussed.

The Assessment of Climatological Impacts on Agricultural Production and Residential Energy Demand

Science.gov (United States)

Cooter, Ellen Jean

The assessment of climatological impacts on selected economic activities is presented as a multi-step, inter -disciplinary problem. The assessment process which is addressed explicitly in this report focuses on (1) user identification, (2) direct impact model selection, (3) methodological development, (4) product development and (5) product communication. Two user groups of major economic importance were selected for study; agriculture and gas utilities. The broad agricultural sector is further defined as U.S.A. corn production. The general category of utilities is narrowed to Oklahoma residential gas heating demand. The CERES physiological growth model was selected as the process model for corn production. The statistical analysis for corn production suggests that (1) although this is a statistically complex model, it can yield useful impact information, (2) as a result of output distributional biases, traditional statistical techniques are not adequate analytical tools, (3) the model yield distribution as a whole is probably non-Gausian, particularly in the tails and (4) there appears to be identifiable weekly patterns of forecasted yields throughout the growing season. Agricultural quantities developed include point yield impact estimates and distributional characteristics, geographic corn weather distributions, return period estimates, decision making criteria (confidence limits) and time series of indices. These products were communicated in economic terms through the use of a Bayesian decision example and an econometric model. The NBSLD energy load model was selected to represent residential gas heating consumption. A cursory statistical analysis suggests relationships among weather variables across the Oklahoma study sites. No linear trend in "technology -free" modeled energy demand or input weather variables which would correspond to that contained in observed state -level residential energy use was detected. It is suggested that this trend is largely the

On the relationship between Indian summer monsoon withdrawal and Indo-Pacific SST anomalies before and after 1976/1977 climate shift

Energy Technology Data Exchange (ETDEWEB)

Sabeerali, C.T.; Rao, Suryachandra A. [Indian Institute of Tropical Meteorology, Pune (India); Ajayamohan, R.S. [University of Victoria, Canadian Centre for Climate Modelling and Analysis, Victoria, BC (Canada); Murtugudde, Raghu [University of Maryland, Earth System Science Interdisciplinary Center, College Park, MD (United States)

2012-08-15

A clear shift in the withdrawal dates of the Indian Summer Monsoon is observed in the long term time series of rainfall data. Prior (posterior) to the 1976/1977 climate shift most of the withdrawal dates are associated with a late (an early) withdrawal. As a result, the length of the rainy season (LRS) over the Indian land mass has also undergone similar changes (i.e., longer (shorter) LRS prior (posterior) to the climate shift). In this study, probable reasons for this significant shift in withdrawal dates and the LRS are investigated using reanalysis/observed datasets and also with the help of an atmospheric general circulation model. Reanalysis/observational datasets indicate that prior to the climate shift the sea surface temperature (SST) anomalies in the eastern equatorial Pacific Ocean and the Arabian Sea exerted a strong influence on both the withdrawal and the LRS. After the climate shift, the influence of the eastern equatorial Pacific Ocean SST has decreased and surprisingly, the influence of the Arabian Sea SST is almost non-existent. On the other hand, the influence of the southeastern equatorial Indian Ocean has increased significantly. It is observed that the upper tropospheric temperature gradient over the dominant monsoon region has decreased and the relative influence of the Indian Ocean SST variability on the withdrawal of the Indian Summer Monsoon has increased in the post climate shift period. Sensitivity experiments with the contrasting SST patterns on withdrawal dates and the LRS in the pre- and post- climate shift scenarios, confirm the observational evidences presented above. (orig.)

Narp regulates long-term aversive effects of morphine withdrawal

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Reti, Irving M.; Crombag, Hans S.; Takamiya, Kogo; Sutton, Jeffrey M.; Guo, Ning; Dinenna, Megan L.; Huganir, Richard L.; Holland, Peter C.; Baraban, Jay M.

2008-01-01

Although long-lasting effects of drug withdrawal are thought to play a key role in motivating continued drug use, the mechanisms mediating this type of drug-induced plasticity are unclear. As Narp is an immediate early gene product that is secreted at synaptic sites and binds to AMPA receptors, it has been implicated in mediating enduring forms of synaptic plasticity. In previous studies, we found that Narp is selectively induced by morphine withdrawal in the extended amygdala, a group of limbic nuclei that mediate aversive behavioral responses. Accordingly, in this study, we evaluated whether long-term aversive effects of morphine withdrawal are altered in Narp KO mice. We found that acute physical signs of morphine withdrawal are unaffected by Narp deletion. However, Narp KO mice acquire and sustain more aversive responses to the environment conditioned with morphine withdrawal than WT controls. Paradoxically, Narp KO mice undergo accelerated extinction of this heightened aversive response. Taken together, these studies suggest that Narp modulates both acquisition and extinction of aversive responses to morphine withdrawal and, therefore, may regulate plasticity processes underlying drug addiction. PMID:18729628

A case of rhabdomyolysis associated with severe opioid withdrawal.

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Gangahar, Deepali

2015-08-01

While the risk of opioid overdose is widely accepted, the dangers of opioid withdrawal are far less clearly defined. The purpose of this publication is to provide evidence against the erroneous clinical dictum that opioid withdrawal is never life-threatening. This case report (N = 1) illustrates an unfortunate, common scenario of a man abusing prescription opioids and heroin. His attempt at self-detoxification with buprenorphine-naloxone resulted in life-threatening opioid withdrawal. A detailed account of each day of his withdrawal period was documented by patient and family report and review of all medical records. The patient was contacted three months after hospitalization to verify information and determine progress in treatment and abstinence from drugs and alcohol. A review of the literature was completed on severe cases of precipitated and spontaneous opioid withdrawal followed by a discussion of the significance as it relates to this case. Given the widespread use of prescription opioids and opioid maintenance treatment, physicians should be aware of the complications of acute opioid withdrawal and should be equipped to treat these complications. © American Academy of Addiction Psychiatry.

Effects of chronic morphine and morphine withdrawal on gene expression in rat peripheral blood mononuclear cells.

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Desjardins, Stephane; Belkai, Emilie; Crete, Dominique; Cordonnier, Laurie; Scherrmann, Jean-Michel; Noble, Florence; Marie-Claire, Cynthia

2008-12-01

Chronic morphine treatment alters gene expression in brain structures. There are increasing evidences showing a correlation, in gene expression modulation, between blood cells and brain in psychological troubles. To test whether gene expression regulation in blood cells could be found in drug addiction, we investigated gene expression profiles in peripheral blood mononuclear (PBMC) cells of saline and morphine-treated rats. In rats chronically treated with morphine, the behavioral signs of spontaneous withdrawal were observed and a withdrawal score was determined. This score enabled to select the time points at which the animals displayed the mildest and strongest withdrawal signs (12 h and 36 h after the last injection). Oligonucleotide arrays were used to assess differential gene expression in the PBMCs and quantitative real-time RT-PCR to validate the modulation of several candidate genes 12 h and 36 h after the last injection. Among the 812 differentially expressed candidates, several genes (Adcy5, Htr2a) and pathways (Map kinases, G-proteins, integrins) have already been described as modulated in the brain of morphine-treated rats. Sixteen out of the twenty-four tested candidates were validated at 12 h, some of them showed a sustained modulation at 36 h while for most of them the modulation evolved as the withdrawal score increased. This study suggests similarities between the gene expression profile in PBMCs and brain of morphine-treated rats. Thus, the searching of correlations between the severity of the withdrawal and the PBMCs gene expression pattern by transcriptional analysis of blood cells could be promising for the study of the mechanisms of addiction.

Low efficacy of non-opioid drugs in opioid withdrawal symptoms.

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Hermann, Derik; Klages, Eckard; Welzel, Helga; Mann, Karl; Croissant, Bernhard

2005-06-01

Opioid withdrawal, stress or cues associated with opioid consumption can induce opioid craving. If opioids are not available, opioid-dependent patients usually search for alternative drugs. Because several non-opioid drugs stimulate the endogenous opioidergic system, this concept may explain their frequent use by opioid-dependent patients. We hypothesized that non-opioid drugs alleviate opioid withdrawal symptoms and are therefore consumed by opioid addicts. We asked 89 opioid-dependent patients participating in an out-patient opioid maintenance program to estimate the potential of several non-opioid drugs in being able to alleviate opioid withdrawal. We applied a five-point Lickert scale (1 = very good reduction of opioid withdrawal; 5 = no reduction of opioid withdrawal). Patients could also indicate a worsening of opioid withdrawal. Values (mean +/- SD) were: for benzodiazepines, 3.2 +/- 1.1; tricyclic antidepressants, 3.6 +/- 1.1; cannabis, 3.6 +/- 1.0; alcohol, 4.1 +/- 1.1; cocaine, 4.2 +/- 1.1; amphetamine, 4.4 +/- 0.9; nicotine, 4.7 +/- 0.7; and caffeine, 4.9 +/- 0.5. A worsening of opioid withdrawal was reported by 62% of the patients for cocaine, 62% for amphetamine, 50% for caffeine, 37.5% for cannabis, 27% for nicotine, 26% for alcohol, 8% for tricyclic antidepressants and 3% for benzodiazepines. Our study shows a low efficacy of non-opioid drugs in alleviating opioid withdrawal symptoms. The data basis of this study was good and the sample was suitable to be asked for estimations of drug-drug interactions. Of the patients, 26 - 62% even reported a worsening of opioid withdrawal for cannabis, alcohol, cocaine and amphetamine. Only benzodiazepines and tricyclic antidepressants were reported to have a moderate positive effect on opioid withdrawal.

49 CFR 450.16 - Withdrawal of delegation.

Science.gov (United States)

2010-10-01

... 49 Transportation 6 2010-10-01 2010-10-01 false Withdrawal of delegation. 450.16 Section 450.16... SECURITY SAFETY APPROVAL OF CARGO CONTAINERS GENERAL Procedure for Delegation to Approval Authorities § 450.16 Withdrawal of delegation. (a) The Chief, Office of Operating and Environmental Standards (CG-522...

20 CFR 410.690 - Withdrawal of charges.

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2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Withdrawal of charges. 410.690 Section 410.690 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL COAL MINE HEALTH AND SAFETY ACT OF 1969... Review, Finality of Decisions, and Representation of Parties § 410.690 Withdrawal of charges. If an...

Rating Algorithm for Pronunciation of English Based on Audio Feature Pattern Matching

Directory of Open Access Journals (Sweden)

Li Kun

2015-01-01

Full Text Available With the increasing internationalization of China, language communication has become an important channel for us to adapt to the political and economic environment. How to improve English learners’ language learning efficiency in limited conditions has turned into a problem demanding prompt solution at present. This paper applies two pronunciation patterns according to the actual needs of English pronunciation rating: to-be-evaluated pronunciation pattern and standard pronunciation pattern. It will translate the patterns into English pronunciation rating results through European distance. Besides, this paper will introduce the design philosophy of the whole algorithm in combination with CHMM matching pattern. Each link of the CHMM pattern will be given selective analysis while a contrast experiment between the CHMM matching pattern and the other two patterns will be conducted. From the experiment results, it can be concluded that CHMM pattern is the best option.

CONSUMER'S RIGHT TO WITHDRAW

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ANCA NICOLETA GHEORGHE

2013-05-01

Full Text Available The right of withdrawal (of a contract belongs to the consumer, and is an essential means for the improvement of regulations that protect the consumer.. Right of withdrawal is not a recent creation and is not even specific to the consumer field. He was previously recognized in civil and commercial law (without special regulation. The right to withdraw may even have as ground the parties will. Thus, based on the contractual freedom, the parties may agree that one of them has the right to terminate the contract unilaterally The possibility of unilateral denunciation of the contract, gives the consumer, added protection by being able to reflect the decision and to check how the trader fulfil its obligations. In this context, through its effects, the right of denunciation, forces the professional parties to conduct themselves as fair as possible to the consumer and to execute the contract properly. In the study of the consumer protection, the time of conclusion is essential because in this stage is manifested, the inequality between the consumer and professional. Thus, the lack of information, the major of products and activities, commercial practices, influence the formation of consumer will, preventing the expression of a freely and knowingly consent.

Neural mechanisms underlying morphine withdrawal in addicted patients: a review

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Nima Babhadiashar

2015-06-01

Full Text Available Morphine is one of the most potent alkaloid in opium, which has substantial medical uses and needs and it is the first active principle purified from herbal source. Morphine has commonly been used for relief of moderate to severe pain as it acts directly on the central nervous system; nonetheless, its chronic abuse increases tolerance and physical dependence, which is commonly known as opiate addiction. Morphine withdrawal syndrome is physiological and behavioral symptoms that stem from prolonged exposure to morphine. A majority of brain regions are hypofunctional over prolonged abstinence and acute morphine withdrawal. Furthermore, several neural mechanisms are likely to contribute to morphine withdrawal. The present review summarizes the literature pertaining to neural mechanisms underlying morphine withdrawal. Despite the fact that morphine withdrawal is a complex process, it is suggested that neural mechanisms play key roles in morphine withdrawal.

Small Business Demand Response with Communicating Thermostats: SMUD's Summer Solutions Research Pilot

Energy Technology Data Exchange (ETDEWEB)

Herter, Karen; Wayland, Seth; Rasin, Josh

2009-09-25

This report documents a field study of 78 small commercial customers in the Sacramento Municipal Utility District service territory who volunteered for an integrated energy-efficiency/demand-response (EE-DR) program in the summer of 2008. The original objective for the pilot was to provide a better understanding of demand response issues in the small commercial sector. Early findings justified a focus on offering small businesses (1) help with the energy efficiency of their buildings in exchange for occasional load shed, and (2) a portfolio of options to meet the needs of a diverse customer sector. To meet these expressed needs, the research pilot provided on-site energy efficiency advice and offered participants several program options, including the choice of either a dynamic rate or monthly payment for air-conditioning setpoint control. An analysis of hourly load data indicates that the offices and retail stores in our sample provided significant demand response, while the restaurants did not. Thermostat data provides further evidence that restaurants attempted to precool and reduce AC service during event hours, but were unable to because their air-conditioning units were undersized. On a 100 F reference day, load impacts of all participants during events averaged 14%, while load impacts of office and retail buildings (excluding restaurants) reached 20%. Overall, pilot participants including restaurants had 2007-2008 summer energy savings of 20% and bill savings of 30%. About 80% of participants said that the program met or surpassed their expectations, and three-quarters said they would probably or definitely participate again without the $120 participation incentive. These results provide evidence that energy efficiency programs, dynamic rates and load control programs can be used concurrently and effectively in the small business sector, and that communicating thermostats are a reliable tool for providing air-conditioning load shed and enhancing the ability

On-Demand Sensor Node Wake-Up Using Solar Panels and Visible Light Communication

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Carolina Carrascal

2016-03-01

Full Text Available To significantly reduce, or eliminate completely, the energy waste caused by the standby (idle mode of wireless sensor nodes, we propose a novel on-demand wake-up system, which allows the nodes to be put into sleep mode unless their activation is truly necessary. Although there have been many studies proposing RF-based wake-up radio systems, in this work, we develop the first visible light communication (VLC-based wake-up system. The developed system can extend the existing VLC systems and can be exploited to derive new application areas such as VLC tags. The system uses an off-the-shell indoor solar panel as receptor device of the wake-up signal as well as for energy harvesting purposes, through which it is able to harvest enough energy for its autonomous work. The design, implementation details and the experimental evaluation results are presented, which include flickering characterization and wake-up range evaluations. The results show that the developed system achieve reasonable wake-up distances for indoor environments, mainly where the use of VLC systems are considered.

On-Demand Sensor Node Wake-Up Using Solar Panels and Visible Light Communication.

Science.gov (United States)

Carrascal, Carolina; Demirkol, Ilker; Paradells, Josep

2016-03-22

To significantly reduce, or eliminate completely, the energy waste caused by the standby (idle) mode of wireless sensor nodes, we propose a novel on-demand wake-up system, which allows the nodes to be put into sleep mode unless their activation is truly necessary. Although there have been many studies proposing RF-based wake-up radio systems, in this work, we develop the first visible light communication (VLC)-based wake-up system. The developed system can extend the existing VLC systems and can be exploited to derive new application areas such as VLC tags. The system uses an off-the-shell indoor solar panel as receptor device of the wake-up signal as well as for energy harvesting purposes, through which it is able to harvest enough energy for its autonomous work. The design, implementation details and the experimental evaluation results are presented, which include flickering characterization and wake-up range evaluations. The results show that the developed system achieve reasonable wake-up distances for indoor environments, mainly where the use of VLC systems are considered.

Current and future groundwater withdrawals: Effects, management and energy policy options for a semi-arid Indian watershed

Science.gov (United States)

Sishodia, Rajendra P.; Shukla, Sanjay; Graham, Wendy D.; Wani, Suhas P.; Jones, James W.; Heaney, James

2017-12-01

Effects of future expansion/intensification of irrigated agriculture on groundwater and surface water levels and availability in a semi-arid watershed were evaluated using an integrated hydrologic model (MIKE SHE/MIKE 11) in conjunction with biophysical measurements. Improved water use efficiency, water storage, and energy policy options were evaluated for their ability to sustain the future (2035) increased groundwater withdrawals. Three future withdrawal scenarios (low = 20, medium = 30, high = 50 wells/100 km2/year) based on the historical rate of growth of irrigation wells were formulated. While well drying from falling groundwater levels was limited to drought and consecutive below average rainfall years, under the current (2015) withdrawals, significant increases in frequency and duration (17-97 days/year) of well drying along with 13-26% (19-37 mm) reductions in surface flows were predicted under the future withdrawals. Higher (27-108%) energy demands of existing irrigation pumps due to declining groundwater levels and reduced hydroelectric generation due to decreased surface flows would create a vicious water-food-energy nexus in the future. Crop failure, one of the main causes of farmers' emotional distress and death in the region, is predicted to exacerbate under the future withdrawal scenarios. Shift to negative net recharge (-63 mm) and early and prolonged drying of wells under the high scenario will reduce the groundwater availability and negatively affect crop production in more than 60% and 90% of cropped areas in the Rabi (November-February) and summer (March-May) seasons, respectively during a drought year. Individual and combined demand (drip irrigation and reduced farm electricity subsidy) and supply (water storage) management options improved groundwater levels and reduced well drying by 55-97 days/year compared to business-as-usual management under the high scenario. The combined management (50% drip conversion, 50% reduction in subsidy, and

A study on family communication pattern and parenting styles with quality of life in adolescent.

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Sanavi, Fariba Shahhraki; Baghbanian, Abdolvahab; Shovey, Mehdi Faraji; Ansari-Moghaddam, Alireza

2013-11-01

To investigate the relationship between parenting styles and family communication patterns with adolescent's quality of life. The cross-sectional study was carried out on 439 randomly selected adolescents in the city of Zahedan, Iran, from January to July 2011.The subjects were asked to complete the KIDSCREEN-52 health-related quality of life questionnaire, while their parents were asked to complete the Diana Brinder's Test to show their parenting styles. SPSS 15 was used to analyse data. Most parents had 'authoritative' parenting style (n = 380; 86.6%). Pluralistic (n = 170; 38.7%) and consensual (n = 152; 34.6%) patterns were the most frequent styles of communication in families. Data suggested a significant relationship between parenting style and some dimensions of quality of life, including physical well-being, psychological well-being, social support and peers, and autonomy (p parent relation and home life (p parents while raising their children.

Multi-Connection Pattern Analysis: Decoding the representational content of neural communication.

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Li, Yuanning; Richardson, Robert Mark; Ghuman, Avniel Singh

2017-11-15

The lack of multivariate methods for decoding the representational content of interregional neural communication has left it difficult to know what information is represented in distributed brain circuit interactions. Here we present Multi-Connection Pattern Analysis (MCPA), which works by learning mappings between the activity patterns of the populations as a factor of the information being processed. These maps are used to predict the activity from one neural population based on the activity from the other population. Successful MCPA-based decoding indicates the involvement of distributed computational processing and provides a framework for probing the representational structure of the interaction. Simulations demonstrate the efficacy of MCPA in realistic circumstances. In addition, we demonstrate that MCPA can be applied to different signal modalities to evaluate a variety of hypothesis associated with information coding in neural communications. We apply MCPA to fMRI and human intracranial electrophysiological data to provide a proof-of-concept of the utility of this method for decoding individual natural images and faces in functional connectivity data. We further use a MCPA-based representational similarity analysis to illustrate how MCPA may be used to test computational models of information transfer among regions of the visual processing stream. Thus, MCPA can be used to assess the information represented in the coupled activity of interacting neural circuits and probe the underlying principles of information transformation between regions. Copyright © 2017 Elsevier Inc. All rights reserved.

Spatial analysis of electricity demand patterns in Greece: Application of a GIS-based methodological framework

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Tyralis, Hristos; Mamassis, Nikos; Photis, Yorgos N.

2016-04-01

We investigate various uses of electricity demand in Greece (agricultural, commercial, domestic, industrial use as well as use for public and municipal authorities and street lightning) and we examine their relation with variables such as population, total area, population density and the Gross Domestic Product. The analysis is performed on data which span from 2008 to 2012 and have annual temporal resolution and spatial resolution down to the level of prefecture. We both visualize the results of the analysis and we perform cluster and outlier analysis using the Anselin local Moran's I statistic as well as hot spot analysis using the Getis-Ord Gi* statistic. The definition of the spatial patterns and relationships of the aforementioned variables in a GIS environment provides meaningful insight and better understanding of the regional development model in Greece and justifies the basis for an energy demand forecasting methodology. Acknowledgement: This research has been partly financed by the European Union (European Social Fund - ESF) and Greek national funds through the Operational Program "Education and Lifelong Learning" of the National Strategic Reference Framework (NSRF) - Research Funding Program: ARISTEIA II: Reinforcement of the interdisciplinary and/ or inter-institutional research and innovation (CRESSENDO project; grant number 5145).

Opioid antagonists with minimal sedation for opioid withdrawal.

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Gowing, Linda; Ali, Robert; White, Jason M

2017-05-29

Managed withdrawal is a necessary step prior to drug-free treatment or as the endpoint of long-term substitution treatment. To assess the effects of opioid antagonists plus minimal sedation for opioid withdrawal. Comparators were placebo as well as more established approaches to detoxification, such as tapered doses of methadone, adrenergic agonists, buprenorphine and symptomatic medications. We updated our searches of the following databases to December 2016: CENTRAL, MEDLINE, Embase, PsycINFO and Web of Science. We also searched two trials registers and checked the reference lists of included studies for further references to relevant studies. We included randomised and quasi-randomised controlled clinical trials along with prospective controlled cohort studies comparing opioid antagonists plus minimal sedation versus other approaches or different opioid antagonist regimens for withdrawal in opioid-dependent participants. We used standard methodological procedures expected by Cochrane. Ten studies (6 randomised controlled trials and 4 prospective cohort studies, involving 955 participants) met the inclusion criteria for the review. We considered 7 of the 10 studies to be at high risk of bias in at least one of the domains we assessed.Nine studies compared an opioid antagonist-adrenergic agonist combination versus a treatment regimen based primarily on an alpha 2 -adrenergic agonist (clonidine or lofexidine). Other comparisons (placebo, tapered doses of methadone, buprenorphine) made by included studies were too diverse for any meaningful analysis. This review therefore focuses on the nine studies comparing an opioid antagonist (naltrexone or naloxone) plus clonidine or lofexidine versus treatment primarily based on clonidine or lofexidine.Five studies took place in an inpatient setting, two studies were in outpatients with day care, two used day care only for the first day of opioid antagonist administration, and one study described the setting as outpatient

Gradual withdrawal of remifentanil infusion may prevent opioid-induced hyperalgesia.

Science.gov (United States)

Comelon, M; Raeder, J; Stubhaug, A; Nielsen, C S; Draegni, T; Lenz, H

2016-04-01

The aim of this study was to examine if gradual withdrawal of remifentanil infusion prevented opioid-induced hyperalgesia (OIH) as opposed to abrupt withdrawal. OIH duration was also evaluated. Nineteen volunteers were enrolled in this randomized, double-blinded, placebo-controlled, crossover study. All went through three sessions: abrupt or gradual withdrawal of remifentanil infusion and placebo. Remifentanil was administered at 2.5 ng ml(-1) for 30 min before abrupt withdrawal or gradual withdrawal by 0.6 ng ml(-1) every five min. Pain was assessed at baseline, during infusion, 45-50 min and 105-110 min after end of infusions using the heat pain test (HPT) and the cold pressor test (CPT). The HPT 45 min after infusion indicated OIH development in the abrupt withdrawal session with higher pain scores compared with the gradual withdrawal and placebo sessions (both Pwithdrawal compared with placebo (P=0.93). In the CPT 50 min after end of infusion there was OIH in both remifentanil sessions compared with placebo (gradual P=0.01, abrupt Pwithdrawal of remifentanil infusion in the HPT. After abrupt withdrawal OIH was present in the HPT. In the CPT there was OIH after both gradual and abrupt withdrawal of infusion. The duration of OIH was less than 105 min for both pain modalities. NCT 01702389. EudraCT number 2011-002734-39. © The Author 2016. Published by Oxford University Press on behalf of the British Journal of Anaesthesia. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Two-day thionamide withdrawal prior to radioiodine uptake sufficiently increases uptake and does not exacerbate hyperthyroidism compared to 7-day withdrawal in Graves' disease

International Nuclear Information System (INIS)

Kubota, Sumihisa; Ohye, Hidemi; Yano, Genichiro; Nishihara, Eijun; Kudo, Takumi; Ito, Mitsuru; Fukata, Shuji; Amino, Nobuyuki; Kuma, Kanji; Miyauchi, Akira

2006-01-01

The appropriate period of antithyroid drug (ATD) discontinuation before radioiodine therapy is the most critical problem in Graves' disease patients under going treatment with ATD. To determine the optimal period that does not alter the outcome of radioiodine therapy or exacerbate hyperthyroidism, we compared serum FT4 levels at radioiodine uptake (RAIU) and therapy outcomes between a 2-day withdrawal group and 7-day withdrawal group. We prospectively recruited 43 patients for the 2-day withdrawal protocol and retrospectively reviewed 49 patients treated with radioiodine following the protocol of 7-day withdrawal. There was no significant difference in RAIU between the 2 groups. The mean serum FT4 level measured on the first day of 24-h RAIU of the 7-day group was significantly higher than that in the 2-day group. There were no significant differences in the outcomes at each point (6 months, 1 year, and 2 years after therapy) between the 2 groups. Our results indicated that withdrawal of ATD for 2 days is superior to 7 days in that 2 days discontinuation did not exacerbate hyperthyroidism. In order to prevent serum thyroid hormone increase after ATD withdrawal and radioiodine therapy, a 2-day ATD withdrawal period before radioiodine therapy may be useful for high-risk patients such as the elderly and patients with cardiac complications. We believe that the 2-day ATD withdrawal method may be useful for patients undergoing treatment with ATD who are to undergo radioiodine therapy. (author)

Effects of caffeine and caffeine withdrawal on mood and cognitive performance degraded by sleep restriction.

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Rogers, Peter J; Heatherley, Susan V; Hayward, Robert C; Seers, Helen E; Hill, Joanne; Kane, Marian

2005-06-01

effects. Different patterns of effects (or lack of effects) of caffeine and caffeine withdrawal were found for other variables, but overall these results also suggest that there is little benefit to be gained from caffeine consumption.

Acute coronary ischemia during alcohol withdrawal: a case report

Directory of Open Access Journals (Sweden)

Sriram Ganeshalingam

2011-08-01

Full Text Available Abstract Introduction The potential of alcohol withdrawal to cause acute coronary events is an area that needs the urgent attention of clinicians and researchers. Case presentation We report the case of a 52-year-old heavy-alcohol-using Sri Lankan man who developed electocardiogram changes suggestive of an acute coronary event during alcohol withdrawal. Despite the patient being asymptomatic, subsequent echocardiogram showed evidence of ischemic myocardial dysfunction. We review the literature on precipitation of myocardial ischemia during alcohol withdrawal and propose possible mechanisms. Conclusions Alcohol withdrawal is a commonly observed phenomenon in hospitals. However, the number of cases reported in the literature of acute coronary events occurring during withdrawal is few. Many cases of acute ischemia or sudden cardiac deaths may be attributed to other well known complications of delirium tremens. This is an area needing the urgent attention of clinicians and epidemiologists.

Overlapping and permeability: Research on the pattern hierarchy of communication space and design strategy based on environmental behavior

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Leilei, Sun; Liang, Zhang; Bing, Chen; Hong, Xi

2017-11-01

This thesis is to analyze the basic pattern hierarchy of communication space by using the theory of environmental psychology and behavior combined with relevant principles in architecture, to evaluate the design and improvement of communication space in specific meaning, and to bring new observation ideas and innovation in design methods to the system of space, environment and behavior.

Communication and laboratory performance in parapsychology experiments: demand characteristics and the social organization of interaction.

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Wooffitt, Robin

2007-09-01

This paper reports findings from a conversation analytic study of experimenter-participant interaction in parapsychology experiments. It shows how properties of communication through which the routine business of the experiment is conducted may have an impact on the research participant's subsequent performance. In this, the study explores social psychological features of the psychology laboratory. In particular, it examines aspects of Orne's (1962) account of what he called the demand characteristics of the psychological experiment. The data come from a corpus of audio recordings of experimenter-participant interaction during experiments on extra-sensory perception. These kinds of experiments, and the phenomena they purport to study, are undoubtedly controversial; however, the paper argues that there are grounds for social psychologists to consider parapsychology experiments as a class (albeit distinctive) of psychology experiments, and, therefore, as sites in which general social psychological and communicative phenomena can be studied. The empirical sections of the paper examine interaction during part of the experimental procedure when the experimenter verbally reviews a record of the participant's imagery reported during an earlier part of the experiment. The analysis shows that the way in which the experimenter acknowledges the research participants' utterances may be significant for the trajectory of the experiment and explores how the participants' subsequent performance in the experiment may be influenced by interactionally generated contingencies.

Energy demand: Facts and trends

Energy Technology Data Exchange (ETDEWEB)

Chateau, B; Lapillonne, B

1982-01-01

The relationship between economic development and energy demand is investigated in this book. It gives a detailed analysis of the energy demand dynamics in industrialized countries and compares the past evolution of the driving factors behind energy demand by sector and by end-uses for the main OECD countries: residential sector (space heating, water heating, cooking...), tertiary sector, passenger and goods transport by mode, and industry (with particular emphasis on the steel and cement industry). This analysis leads to a more precise understanding of the long-term trends of energy demand; highlighting the influence on these trends of energy prices, especially after the oil price shocks, and of the type of economic development pattern.

TRACY transient experiment databook. 2) ramp withdrawal experiment

International Nuclear Information System (INIS)

Nakajima, Ken; Yamane, Yuichi; Ogawa, Kazuhiko; Aizawa, Eiju; Yanagisawa, Hiroshi; Miyoshi, Yoshinori

2002-03-01

This is a databook of TRACY ''ramp withdrawal'' experiments. TRACY is a reactor to perform supercritical experiments using low-enriched uranyl nitrate aqueous solution. The excess reactivity of TRACY is 3$ at maximum, and it is inserted by feeding the solution to a core tank or by withdrawing a control rod, which is called as the transient rod, from the core. In the ramp withdrawal experiment, the supercritical experiment is initiated by withdrawing the transient rod from the core in a constant speed using a motor drive system. The data in the present databook consist of datasheets and graphs. Experimental conditions and typical values of measured parameters are tabulated in the datasheet. In the graph, power and temperature profiles are plotted. Those data are useful for the investigation of criticality accidents with fissile solutions, and for validation of criticality accident analysis codes. (author)

Cannabis Withdrawal in Adults With Attention-Deficit/Hyperactivity Disorder.

Science.gov (United States)

Chauchard, Emeline; Hartwell, Karen J; McRae-Clark, Aimee L; Sherman, Brian J; Gorelick, David A

2018-02-22

Cannabis withdrawal has not been studied in adults with attention-deficit/hyperactivity disorder (ADHD) who have high rates of cannabis use. We aimed to describe cannabis withdrawal, motivations to quit, and strategies to quit cannabis use in cannabis-dependent adults with ADHD. Twenty-three adults with ADHD enrolled in a controlled clinical trial of pharmacotherapy (atomoxetine) for cannabis dependence (DSM-IV criteria) completed the Marijuana Quit Questionnaire (MJQQ) to provide information on their "most serious" quit attempt made without formal treatment. The study was conducted between November 2005 and June 2008. Participants were predominantly male (82.6%, n = 19), with a mean (SD) age of 27.4 (8.5) years (range, 18-53) at the start of their index quit attempt. The most common motive for quitting cannabis was "to save money" (87%, n = 20); the most common strategy to maintain abstinence was "stopped associating with people who smoke marijuana" (43%, n = 10). Almost all (96%, n = 22) subjects reported ≥ 1 cannabis withdrawal symptom; 7 (30%) met DSM-5 diagnostic criteria for cannabis withdrawal syndrome. Participants with comorbid ADHD and cannabis dependence reported withdrawal symptoms similar to other samples of non-treatment-seeking cannabis-dependent adults with no psychiatric comorbidity. These findings suggest that ADHD does not influence cannabis withdrawal in the way that it does tobacco (nicotine) withdrawal. Data used in this secondary analysis came from ClinicalTrials.gov identifier: NCT00360269. © Copyright 2018 Physicians Postgraduate Press, Inc.

Balancing food security and water demand for freshwater ecosystems

Science.gov (United States)

Pastor, Amandine; Palazzo, Amanda; Havlik, Petr; Obersteiner, Michael; Biemans, Hester; Wada, Yoshihide; Kabat, Pavel; Ludwig, Fulco

2017-04-01

Water is not an infinite resource and demand from irrigation, household and industry is constantly increasing. This study focused on including global water availability including environmental flow requirements with water withdrawal from irrigation and other sectors at a monthly time-step in the GLOBIOM model. This model allows re-adjustment of land-use allocation, crop management, consumption and international trade. The GLOBIOM model induces an endogenous change in water price depending on water supply and demand. In this study, the focus was on how the inclusion of water resources affects land-use and, in particular, how global change will influence repartition of irrigated and rainfed lands at global scale. We used the climate change scenario including a radiative forcing of 8.5 W/m2 (RCP8.5), the socio-economic scenario (SSP2: middle-of-road), and the environmental flow method based on monthly flow allocation (the Variable Monthly Flow method) with high and low restrictions. Irrigation withdrawals were adjusted to a monthly time-step to account for biophysical water limitations at finer time resolution. Our results show that irrigated land might decrease up to 40% on average depending on the choice of EFR restrictions. Several areas were identified as future hot-spots of water stress such as the Mediterranean and Middle-East regions. Other countries were identified to be in safe position in terms of water stress such as North-European countries. Re-allocation of rainfed and irrigated land might be useful information for land-use planners and water managers at an international level to decide on appropriate legislations on climate change mitigation/adaptation when exposure and sensitivity to climate change is high and/or on adaptation measures to face increasing water demand. For example, some countries are likely to adopt measures to increase their water use efficiencies (irrigation system, soil and water conservation practices) to face water shortages, while

40 CFR 97.86 - Withdrawal from NOX Budget Trading Program.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Withdrawal from NOX Budget Trading... PROGRAMS (CONTINUED) FEDERAL NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS Individual Unit Opt-ins. § 97.86 Withdrawal from NOX Budget Trading Program. (a) Requesting withdrawal. To...

42 CFR 8.6 - Withdrawal of approval of accreditation bodies.

Science.gov (United States)

2010-10-01

... PROVISIONS CERTIFICATION OF OPIOID TREATMENT PROGRAMS Accreditation § 8.6 Withdrawal of approval of... 42 Public Health 1 2010-10-01 2010-10-01 false Withdrawal of approval of accreditation bodies. 8.6... to establish that the problems that were grounds for withdrawal of approval have been resolved. (2...

Neurobiology of opioid withdrawal: Role of the endothelin system.

Science.gov (United States)

Bhalla, Shaifali; Andurkar, Shridhar V; Gulati, Anil

2016-08-15

Morphine and oxycodone are potent opioid analgesics most commonly used for the management of moderate to severe acute and chronic pain. Their clinical utility is limited by undesired side effects like analgesic tolerance, dependence, and withdrawal. We have previously demonstrated that endothelin-A (ETA) receptor antagonists potentiate opioid analgesia and eliminate analgesic tolerance. Mechanistically, G proteins and regulatory proteins such as β-arrestins have shown to play an important role in mediating opioid tolerance, dependence, and withdrawal. Recently, the involvement of central ET mechanisms in opioid withdrawal was investigated. ETA receptor antagonist was shown to block majority of the signs and symptoms associated with opioid withdrawal. This review focuses on ET as one of the potential novel strategies to manage the challenge of opioid withdrawal. An overview of additional players in this process (G proteins and β-arrestin2), and the possible therapeutic implications of these findings are presented. Copyright © 2016 Elsevier Inc. All rights reserved.

Tobacco withdrawal symptoms mediate motivation to reinstate smoking during abstinence.

Science.gov (United States)

Aguirre, Claudia G; Madrid, Jillian; Leventhal, Adam M

2015-08-01

Withdrawal-based theories of addiction hypothesize that motivation to reinstate drug use following acute abstinence is mediated by withdrawal symptoms. Experimental tests of this hypothesis in the tobacco literature are scant and may be subject to methodological limitations. This study utilized a robust within-subject laboratory experimental design to investigate the extent to which composite tobacco withdrawal symptomatology level and 3 unique withdrawal components (i.e., low positive affect, negative affect, and urge to smoke) mediated the effect of smoking abstinence on motivation to reinstate smoking. Smokers (≥10 cigarettes per day; N = 286) attended 2 counterbalanced sessions at which abstinence duration was differentially manipulated (1 hr vs. 17 hr). At both sessions, participants reported current withdrawal symptoms and subsequently completed a task in which they were monetarily rewarded proportional to the length of time they delayed initiating smoking, with shorter latency reflecting stronger motivation to reinstate smoking. Abstinence reduced latency to smoking initiation and positive affect and increased composite withdrawal symptom level, urge, and negative affect. Abstinence-induced reductions in latency to initiating smoking were mediated by each withdrawal component, with stronger effects operating through urge. Combined analyses suggested that urge, negative affect, and low positive affect operate through empirically unique mediational pathways. Secondary analyses suggested similar effects on smoking quantity, few differences among specific urge and affect subtypes, and that dependence amplifies some abstinence effects. This study provides the first experimental evidence that within-person variation in abstinence impacts motivation to reinstate drug use through withdrawal. Urge, negative affect, and low positive affect may reflect unique withdrawal-mediated mechanisms underlying tobacco addiction. (c) 2015 APA, all rights reserved).

Social Withdrawal, Friendship, and Depressed Mood in Adolescents

NARCIS (Netherlands)

Aleva, A.E.|info:eu-repo/dai/nl/141299789; van Beek, Y.|info:eu-repo/dai/nl/107292300

2017-01-01

Social withdrawal in children may develop into a depressed mood in early adolescence , through experiences of problematic peer relationships, while friendship may function as a buffer (Rubin, Coplan, & Bowker, 2009). Our study examines the predictive relation between social withdrawal and depressive

Nonlinear Pricing in Markets with Interdependent Demand

OpenAIRE

Shmuel S. Oren; Stephen A. Smith; Robert B. Wilson

1982-01-01

This paper provides a mathematical framework for modeling demand and determining optimal price schedules in markets which have demand externalities and can sustain nonlinear pricing. These fundamental economic concepts appear in the marketplace in the form of mutual buyers' benefits and quantity discounts. The theory addressing these aspects is relevant to a wide variety of goods and services. Examples include tariffs for electronic communications services, pricing of franchises, and royalty ...

Environmental enrichment may protect against neural and behavioural damage caused by withdrawal from chronic alcohol intake.

Science.gov (United States)

Nobre, Manoel Jorge

2016-12-01

Exposure to stress and prolonged exposure to alcohol leads to neuronal damages in several brain regions, being the medial prefrontal cortex (mPFC) one of the most affected. These changes presumably reduce the ability of the organism to cope with these stimuli and may underlie a series of maladaptive behaviours among which include drug addiction and withdrawal. Drug-addicted individuals show a pattern of behavior similar to patients with lesions of the mPFC. This impairment in the decision-making could be one of the mechanisms responsible for the transition from the casual to compulsive drug use. The environmental enrichment (EE) has a protective effect on the neural and cognitive impairments induced by psychoactive drugs, including ethyl alcohol. The present study aims to determine the influence of withdrawal from intermittent long-term alcohol exposure on alcohol preference, emotional reactivity and neural aspects of early isolated or grouped reared rats kept under standard or complex environments and the influence of social isolation on these measures, as well. Our results point out new insights on this matter showing that the EE can attenuate the adverse effects of withdrawal and social isolation on rat's behavior. This effect is probably due to its protective action on the mPFC integrity, including the cingulate area 1 (Cg1), and the prelimbic (PrL) and infralimbic cortex (IL), what could account for the absence of changes in the emotional reactivity in EE alcohol withdrawal rats. We argue that morphological changes at these cortical levels can afford the emotional, cognitive and behavioural dysregulations verified following withdrawal from chronic alcohol intake. Copyright © 2016 ISDN. Published by Elsevier Ltd. All rights reserved.

Hourly price elasticity pattern of electricity demand in the German day-ahead market

OpenAIRE

Knaut, Andreas; Paulus, Simon

2016-01-01

System security in electricity markets relies crucially on the interaction between demand and supply over time. However, research on electricity markets has been mainly focusing on the supply side arguing that demand is rather inelastic. Assuming perfectly inelastic demand might lead to delusive statements regarding the price formation in electricity markets. In this article we quantify the short-run price elasticity of electricity demand in the German day-ahead market and show that demand is...

Socio-Semiotic Patterns in Digital Meaning-Making: Semiotic Choice as Indicator of Communicative Experience

Science.gov (United States)

Sofkova Hashemi, Sylvana

2017-01-01

Access to digital technology in the classroom enables the composition and organization of ideas on screen with a variety of semiotic systems of different modes and media. This study explores patterns of communication and preference of design in digital meaning-making of twelve 7-8 years old students. Meanings were shaped in complex uses and…

Identification and Description of Healthcare Customer Communication Patterns Among Individuals with Diabetes in Clalit Health Services: A Retrospective Database Study.

Science.gov (United States)

Benis, Arriel; Harel, Nissim; Barkan, Refael; Sela, Tomer; Feldman, Becca

2017-01-01

HMOs record medical data and their interactions with patients. Using this data we strive to identify sub-populations of healthcare customers based on their communication patterns and characterize these sub-populations by their socio-demographic, medical, treatment effectiveness, and treatment adherence profiles. This work will be used to develop tools and interventions aimed at improving patient care. The process included: (1) Extracting socio-demographic, clinical, laboratory, and communication data of 309,460 patients with diabetes in 2015, aged 32+ years, having 7+ years of the disease treated by Clalit Healthcare Services; (2) Reducing dimensions of continuous variables; (3) Finding the K communication-patterns clusters; (4) Building a hierarchical clustering and its associated heatmap to summarize the discovered clusters; (5) Analyzing the clusters found; (6) Validating results epidemiologically. Such a process supports understanding different communication-channel usage and the implementation of personalized services focusing on patients' needs and preferences.

Prolonged social withdrawal disorder: a hikikomori case in Spain.

Science.gov (United States)

Ovejero, Santiago; Caro-Cañizares, Irene; de León-Martínez, Victoria; Baca-Garcia, Enrique

2014-09-01

The Japanese term hikikomori means literally 'to be confined'. Social withdrawal can be present in severe psychiatric disorders; however, in Japan, hikikomori is a defined nosologic entity. There have been only a few reported cases in occidental culture. We present a case report of a Spanish man with prolonged social withdrawal lasting for 4 years. This is a case of prolonged social withdrawal not bound to culture, as well as the second case of hikikomori reported in Spain. We propose prolonged social withdrawal disorder as a disorder not linked to culture, in contrast to hikikomori. Further documentation of this disorder is still needed to encompass all cases reported in Japan and around the world. © The Author(s) 2013.

Alcohol withdrawal delirium manifested by manic symptoms in an elderly patient.

Science.gov (United States)

Chan, Hung-Yu; Lee, Kuan-I

2015-03-01

Alcohol withdrawal syndrome is a commonly seen problem in psychiatric practice. Alcohol withdrawal delirium is associated with significant morbidity and mortality. Withdrawal symptoms usually include tremulousness, psychotic and perceptual symptoms, seizures, and consciousness disturbance. Herein, we report a case involving a 63-year-old man who had alcohol withdrawal delirium that was manifested mainly by manic symptoms. © 2014 The Authors. Psychogeriatrics © 2014 Japanese Psychogeriatric Society.

Trends and patterns in communication research on Asia: A review of publications in top SSCI journals, 1995-2014

Directory of Open Access Journals (Sweden)

Xun "Sunny" Liu

2017-06-01

Full Text Available Communication research in Asia has enjoyed rapid growth in the 20th century amid Asia’s economic boom, rapid growth in communication technologies and expanded university faculty. To explore the extent to which the rise of Asian communication research continued in the 21st century, a total of 558 publications on Asian communication research in 14 top-ranked SSCI communication journals from 1995 to 2014 were analyzed. Results indicate that the rise of Asian communication research is afoot in the 21st century. However, the results of also suggest patterns of unevenness of the published scholarship in terms of publishing year, journals, region, research topics and methodology: Asian communication research was dominated by East Asia, which was dominated by China, South Korea and Japan; in terms of research areas by topic, Asian communication scholarship focused on a few areas, including media effects, political communication, communication technology, and health communication; in terms of research methodologies, the quantitative approach was found to be dominant in the publications, which accounts for more than twice that of qualitative research.

Social Withdrawal and Maladjustment in a Very Group-Oriented Society

Science.gov (United States)

Valdivia, Ibis Alvarez; Schneider, Barry H.; Chavez, Kenia Lorenzo; Chen, Xinyin

2005-01-01

Elementary-school children in Cuba and Canada participated in measures of loneliness, sociometric status, friendship, aggression, and social withdrawal. Withdrawal was associated with loneliness in the Cuban data from both cohorts, Grade 4 and Grade 6. In the Canadian data, withdrawal was only linked to loneliness in Grade 6. In contrast with…

The impact of senior medical students' personal difficulties on their communication patterns in breaking bad news.

Science.gov (United States)

Meitar, Dafna; Karnieli-Miller, Orit; Eidelman, Shmuel

2009-11-01

To evaluate the possible influence of personal difficulties and barriers that are within the news bearer and his or her self-awareness (SA) of them, on the patterns of communication during encounters involving breaking bad news (BBN). Following an intensive BBN course in 2004, 103 senior medical students at the Sackler School of Medicine, Tel Aviv University, were evaluated for BBN competencies by the analysis of their written descriptions of how they visualized their manner of delivering bad news to a patient described in a challenging vignette. The students were further asked to reflect on their own difficulties and barriers that surfaced in response to reading the narrative presented in the vignette and in delivering the bad news. Using an immersion crystallization narrative analysis method, the authors analyzed the relationship between the students' BBN strategies and their self-perceived barriers and difficulties. Four types of communicators were identified and related to 45 different personal and professional barriers that the students, through self-reflection, found in themselves. These perceived barriers as well as the ability to self-reflect on them influenced their patterns of communication in their envisioned and written-down encounters, including the level of emotional connectedness, information provided, and the chosen focus-of-care paradigm (physician-centered, patient-centered, or relationship-centered). These findings empirically demonstrate that intrapersonal difficulties within the communicator and his or her level of SA about them influenced the manner and content of the communication during the encounter. This finding suggests that enhancing SA and addressing personal and professional difficulties could help physicians' capability to cope with challenging communication tasks. The authors propose a working tool (the Preparatory SPIKES) to facilitate the integration of self-reflection (by identifying personal difficulties) into day-by-day planning

Monitoring device for withdrawing control rods

International Nuclear Information System (INIS)

Higashigawa, Yuichi.

1985-01-01

Purpose: To improve the sensitivity and the responsivity to an equivalent extent to those in the case where local power range monitors are densely arranged near each of the control rods, with no actual but pseudo increase of the number of local power range monitors. Constitution: The monitor arrangement is patterned by utilizing the symmetricity of the reactor core and stored in a monitor designating device. The symmetricity of control rods to be selected and withdrawn by an operator is judged by a control rod symmetry monitoring device, while the symmetricity of the withdrawn control rods is judged by a control rod withdrawal state monitoring device. Then, only when both of the devices judge the symmetricity, the control rods are subjected to gang driving by the control rod drive mechanisms. In this way, monitoring at a high sensitivity and responsivity is enabled with no increase for the number of monitors. (Yoshino, Y.)

Satisfying the demand for financial information in public traded companies

DEFF Research Database (Denmark)

Holm, Claus

A public traded company which wishes to comply with IAS standards and stock exchange requirements for full public disclosure of relevant information faces a major communication task. The Investor Relation policy of such a company has to satisfy a demand for financial information which seems...... line focus to the disclosure of cash flow surrogates like EBITA and EBITDA. Overall, the findings suggest a communication strategy intended to satisfy the demand from the professional analysts. However, the shear number of different key figures and financial ratios identified in the study suggest...

Ethical Analysis of Withdrawing Total Artificial Heart Support.

Science.gov (United States)

DeMartino, Erin S; Wordingham, Sara E; Stulak, John M; Boilson, Barry A; Fuechtmann, Kayla R; Singh, Nausheen; Sulmasy, Daniel P; Pajaro, Octavio E; Mueller, Paul S

2017-05-01

To describe the characteristics of patients who undergo withdrawal of total artificial heart support and to explore the ethical aspects of withdrawing this life-sustaining treatment. We retrospectively reviewed the medical records of all adult recipients of a total artificial heart at Mayo Clinic from the program's inception in 2007 through June 30, 2015. Management of other life-sustaining therapies, approach to end-of-life decision making, engagement of ethics and palliative care consultation, and causes of death were analyzed. Of 47 total artificial heart recipients, 14 patients or their surrogates (30%) requested withdrawal of total artificial heart support. No request was denied by treatment teams. All 14 patients were supported with at least 1 other life-sustaining therapy. Only 1 patient was able to participate in decision making. It is widely held to be ethically permissible to withdraw a life-sustaining treatment when the treatment no longer meets the patient's health care-related goals (ie, the burdens outweigh the benefits). These data suggest that some patients, surrogates, physicians, and other care providers believe that this principle extends to the withdrawal of total artificial heart support. Copyright © 2017 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.

Alcohol Withdrawal Mimicking Organophosphate Poisoning

Directory of Open Access Journals (Sweden)

Nezihat Rana Disel

2014-02-01

Full Text Available Organophosphates, which can cause occupational poisoning due to inappropriate personal protective measures, are widely used insecticides in agricultural regions of southern Turkey. Therefore, the classical clinical findings of this cholinergic poisoning are myosis, excessive secretions, bradicardia and fasciculations are easy to be recognized by local medical stuff. Diseases and conditions related to alcoholism such as mental and social impairments, coma, toxicity, withdrawal, and delirium are frequent causes of emergency visits of chronic alcoholic patients. Here we present a case diagnosed and treated as organophosphate poisoning although it was an alcohol withdrawal in the beginning and became delirium tremens, due to similar symptoms.

Demands for Space Transportation Systems for the next 30 years

Indian Academy of Sciences (India)

First page Back Continue Last page Overview Graphics. Demands for Space Transportation Systems for the next 30 years. Meeting the in-house and commercial launch demand for Communication and Remote Sensing spacecraft. Payload capability enhancement for expendable launch vehicles to meet the national needs.

Induction of synaptic long-term potentiation after opioid withdrawal.

Science.gov (United States)

Drdla, Ruth; Gassner, Matthias; Gingl, Ewald; Sandkühler, Jürgen

2009-07-10

mu-Opioid receptor (MOR) agonists represent the gold standard for the treatment of severe pain but may paradoxically also enhance pain sensitivity, that is, lead to opioid-induced hyperalgesia (OIH). We show that abrupt withdrawal from MOR agonists induces long-term potentiation (LTP) at the first synapse in pain pathways. Induction of opioid withdrawal LTP requires postsynaptic activation of heterotrimeric guanine nucleotide-binding proteins and N-methyl-d-aspartate receptors and a rise of postsynaptic calcium concentrations. In contrast, the acute depression by opioids is induced presynaptically at these synapses. Withdrawal LTP can be prevented by tapered withdrawal and shares pharmacology and signal transduction pathways with OIH. These findings provide a previously unrecognized target to selectively combat pro-nociceptive effects of opioids without compromising opioid analgesia.

Sedative-hypnotic drug withdrawal syndrome: recognition and treatment [digest].

Science.gov (United States)

Santos, Cynthia; Olmedo, Ruben E; Kim, Jeremy

2017-03-22

Sedative-hypnotic drugs include gamma-Aminobutyric acid (GABA)ergic agents such as benzodiazepines, barbiturates, gamma-Hydroxybutyric acid [GHB], gamma-Butyrolactone [GBL], baclofen, and ethanol. Chronic use of these substances can cause tolerance, and abrupt cessation or a reduction in the quantity of the drug can precipitate a life-threatening withdrawal syndrome. Benzodiazepines, phenobarbital, propofol, and other GABA agonists or analogues can effectively control symptoms of withdrawal from GABAergic agents. Managing withdrawal symptoms requires a patient-specific approach that takes into account the physiologic pathways of the particular drugs used as well as the patient's age and comorbidities. Adjunctive therapies include alpha agonists, beta blockers, anticonvulsants, and antipsychotics. Newer pharmacological therapies offer promise in managing withdrawal symptoms. [Points & Pearls is a digest of Emergency Medicine Practice].

Caffeine Withdrawal and Dependence: A Convenience Survey Among Addiction Professionals.

Science.gov (United States)

Budney, Alan J; Brown, Pamela C; Griffiths, Roland R; Hughes, John R; Juliano, Laura M

2013-06-01

Caffeine withdrawal was included in the research appendix of the DSM-IV to encourage additional research to assist with determining its status for the next version of the manual. Caffeine dependence was not included because of a lack of empirical research at the time of publication. This study assessed the beliefs of addiction professionals about the clinical importance of caffeine withdrawal and dependence. A 6-item survey was developed and delivered electronically to the members of six professional organizations that focus on addiction. Open-ended comments were also solicited. Five hundred members responded. The majority (95%) thought that cessation of caffeine could produce a withdrawal syndrome, and that caffeine withdrawal can have clinical importance (73%); however, only half (48%) thought that caffeine withdrawal should be included in the Diagnostic and Statistical Manual of Mental Disorders (DSM). A majority (58%) believed that some people develop caffeine dependence; however, only 44% indicated that it should be in the DSM. Comments suggested that trepidation about inclusion of caffeine diagnoses was due to the concerns about the field of psychiatry being criticized for including common disorders with a relatively low clinical severity. Others, however, expressed an urgent need to take caffeine-related problems more seriously. The majority of addiction professionals believe that caffeine withdrawal and dependence disorders exist and are clinically important; however, these professionals are divided in whether caffeine withdrawal and dependence should be included in DSM. Wider dissemination of the extant literature on caffeine withdrawal and additional research on caffeine dependence will be needed to provide additional guidance to policymakers and healthcare workers.

Sizewell: UK power demand

International Nuclear Information System (INIS)

Anon.

1986-01-01

The Sizewell Inquiry was about whether the next power stations to be built in the UK should be nuclear or coal and, if nuclear, PWRs or AGRs. During the period of the Inquiry forecasts of demand for electricity were low. Now, however, it seems that the forecast demand is much increased. This uncertainty in demand and the wide regional variations are examined in some detail. Facts and figures on electricity sales (area by area) are presented. Also the minutes of supply lost per consumer per year. These show that security of supply is also a problem. It is also shown that the way electricity is used has changed. Whilst electricity generation has been changing to large-scale, centralised power stations the demand patterns may make smaller scale, quickly-constructed units more sensible. The questions considered at the Sizewell Inquiry may, indeed, no longer be the right ones. (UK)

Textbook Factor Demand Curves.

Science.gov (United States)

Davis, Joe C.

1994-01-01

Maintains that teachers and textbook graphics follow the same basic pattern in illustrating changes in demand curves when product prices increase. Asserts that the use of computer graphics will enable teachers to be more precise in their graphic presentation of price elasticity. (CFR)

Store-directed price promotions and communications strategies improve healthier food supply and demand: impact results from a randomized controlled, Baltimore City store-intervention trial.

Science.gov (United States)

Budd, Nadine; Jeffries, Jayne K; Jones-Smith, Jessica; Kharmats, Anna; McDermott, Ann Yelmokas; Gittelsohn, Joel

2017-12-01

Small food store interventions show promise to increase healthy food access in under-resourced areas. However, none have tested the impact of price discounts on healthy food supply and demand. We tested the impact of store-directed price discounts and communications strategies, separately and combined, on the stocking, sales and prices of healthier foods and on storeowner psychosocial factors. Factorial design randomized controlled trial. Twenty-four corner stores in low-income neighbourhoods of Baltimore City, MD, USA. Stores were randomized to pricing intervention, communications intervention, combined pricing and communications intervention, or control. Stores that received the pricing intervention were given a 10-30 % price discount by wholesalers on selected healthier food items during the 6-month trial. Communications stores received visual and interactive materials to promote healthy items, including signage, taste tests and refrigerators. All interventions showed significantly increased stock of promoted foods v. There was a significant treatment effect for daily unit sales of healthy snacks (β=6·4, 95 % CI 0·9, 11·9) and prices of healthy staple foods (β=-0·49, 95 % CI -0·90, -0·03) for the combined group v. control, but not for other intervention groups. There were no significant intervention effects on storeowner psychosocial factors. All interventions led to increased stock of healthier foods. The combined intervention was effective in increasing sales of healthier snacks, even though discounts on snacks were not passed to the consumer. Experimental research in small stores is needed to understand the mechanisms by which store-directed price promotions can increase healthy food supply and demand.

[Alcohol withdrawal syndrome dynamics during treatment with nooclerin (deanoli aceglumas)].

Science.gov (United States)

Agibalova, T V; Buzik, O Zh; Rychkova, O V; Smyshlyaev, A V; Rumbesht, V V

2018-01-01

To study the efficacy of nooclerin (deanoli aceglumas) in alcohol withdrawal syndrome assessed by clinical and biochemical characteristics. A multicenter, open, randomized, comparative study of nooclerin in the complex treatment of alcohol withdrawal syndrome included 90 patients. The patients were randomized into nooclerin group (n=55) and control group (n=35). Nooclerin reduced alcohol withdrawal symptoms more significantly throughout the whole study period. There were significant between-group differences on the Clinical Institute Withdrawal Assessment of Alcohol Scale (CIWA-Ar) and the Multidimensional Fatigue Inventory (МFI-20). However, patients exhibited no excessive activity. No adverse side-effects were observed.

Opioid withdrawal syndrome: emerging concepts and novel therapeutic targets.

Science.gov (United States)

Rehni, Ashish K; Jaggi, Amteshwar S; Singh, Nirmal

2013-02-01

Opioid withdrawal syndrome is a debilitating manifestation of opioid dependence and responds poorly to the available clinical therapies. Studies from various in vivo and in vitro animal models of opioid withdrawal syndrome have led to understanding of its pathobiology which includes complex interrelated pathways leading to adenylyl cyclase superactivation based central excitation. Advancements in the elucidation of opioid withdrawal syndrome mechanisms have revealed a number of key targets that have been hypothesized to modulate clinical status. The present review discusses the neurobiology of opioid withdrawal syndrome and its therapeutic target recptors like calcitonin gene related peptide receptors (CGRP), N-methyl-D-aspartate (NMDA) receptors, gamma aminobutyric acid receptors (GABA), G-proteingated inwardly rectifying potassium (GIRK) channels and calcium channels. The present review further details the potential role of second messengers like calcium (Ca2+) / calmodulin-dependent protein kinase (CaMKII), nitric oxide synthase, cytokines, arachidonic acid metabolites, corticotropin releasing factor, fos and src kinases in causing opioid withdrawal syndrome. The exploitation of these targets may provide effective therapeutic agents for the management of opioid dependence-induced abstinence syndrome.

Monitoring Changes of Ecosystem Services Supply and Demand Pattern in Central and Southern Liaoning Urban Agglomerations, China Using Landsat Images

Science.gov (United States)

Li, B.; Huang, F.; Chang, S.; Qi, H.; Zhai, H.

2018-04-01

Indentifying the spatio-temporal patterns of ecosystem services supply and demand and the driving forces is of great significance to the regional ecological security and sustainable socio-economic development. Due to long term and high-intensity development, the ecological environment in central and southern Liaoning urban agglomerations has been greatly destroyed thereafter has restricted sustainable development in this region. Based on Landsat ETM and OLI images, land use of this urban agglomeration in 2005, 2010 and 2015 was extracted. The integrative index of multiple-ecosystem services (IMES) was used to quantify the supply (IMESs), demand (IMESd) and balance (IMESb) of multiple-ecosystem services, The spatial patterns of ecosystem services and its dynamics for the period of 2005-2015 were revealed. The multiple regression and stepwise regression analysis were used to explore relationships between ecosystem services and socioeconomic factors. The results showed that the IMESs of the region increased by 2.93 %, whereas IMESd dropped 38 %. The undersupplied area was reduced to 2. The IMESs and IMESb were mainly negatively correlated with gross domestic product (GDP), population density, foreign investment and industrial output, while GDP per capita and the number of teachers had significant positive impacts on ecosystem services supply. The positive correlation between IMESd and GDP, population density and foreign investment were found. The ecosystem services models were established. Supply and balance of multiple-ecosystem services were positively correlated with population density, but the demand was the opposite. The results can provide some reference value for the coordinately economic and ecological development in the study area.

Evaluation of Ashwagandha in alcohol withdrawal syndrome

Directory of Open Access Journals (Sweden)

Ruby B

2012-10-01

Full Text Available Objective: To evaluate the effect of Ashwagandha (ASW in attenuation of alcohol withdrawal in ethanol withdrawal mice model. Methods: Alcohol dependence was induced in mice by the oral, once-daily administration of 10% v/v ethanol (2 g/kg for one week. Once the animals were withdrawn from alcohol, the efficacy of ASW (200mg/kg and 500mg/kg in comparison with diazepam (1 mg/kg in the attenuation of withdrawal was studied using, pentylenetetrazole (PTZ kindling test for seizure threshold, forced swim test (FST for depression and locomotor activity (LCA in open field test (OFT. 6 hours after the last ethanol administration, seizure threshold was measured in all the groups by administering the convulsant drug, PTZ with a subconvulsive dose of 30 mg/kg i.p. In FST, mice were forced to swim and the total duration of immobility (seconds was measured during the last 4 min of a single 6-min test session. In OFT, number of crossings of the lines marked on the floor was recorded for a period of 5 min. Results: Compared to ethanol group, ASW (500 mg/Kg has suppressed the PTZ kindling seizures in ethanol withdrawal animals [0% convulsion], FST has shown decreased immobility time and OFT has exhibited increase in the number of line crossing activity by mice which may be the consequence of anxiolytic activity of ASW similar to that of diazepam. Conclusions: The present study provides satisfactory evidence to use ASW as a safe and reliable alternative to diazepam in alcohol withdrawal conditions.

78 FR 12702 - Control of Communicable Diseases: Interstate; Scope and Definitions

Science.gov (United States)

2013-02-25

... Control of Communicable Diseases: Interstate; Scope and Definitions AGENCY: Centers for Disease Control... rulemaking; withdrawal. SUMMARY: The Centers for Disease Control and Prevention (CDC) within the Department... Rulemaking (NPRM) that solicited public comment on updates to the Scope and Definitions for its regulations...

Variability of electricity load patterns and its effect on demand response: A critical peak pricing experiment on Korean commercial and industrial customers

International Nuclear Information System (INIS)

Jang, Dongsik; Eom, Jiyong; Jae Park, Min; Jeung Rho, Jae

2016-01-01

To the extent that demand response represents an intentional electricity usage adjustment to price changes or incentive payments, consumers who exhibit more-variable load patterns on normal days may be capable of altering their loads more significantly in response to dynamic pricing plans. This study investigates the variation in the pre-enrollment load patterns of Korean commercial and industrial electricity customers and their impact on event-day loads during a critical peak pricing experiment in the winter of 2013. Contrary to conventional approaches to profiling electricity loads, this study proposes a new clustering technique based on variability indices that collectively represent the potential demand–response resource that these customers would supply. Our analysis reveals that variability in pre-enrollment load patterns does indeed have great predictive power for estimating their impact on demand–response loads. Customers in relatively low-variability clusters provided limited or no response, whereas customers in relatively high-variability clusters consistently presented large load impacts, accounting for most of the program-level peak reductions. This study suggests that dynamic pricing programs themselves may not offer adequate motivation for meaningful adjustments in load patterns, particularly for customers in low-variability clusters. - Highlights: • A method of clustering customers by variability indices is developed. • Customers in high-variability clusters provide substantial peak reductions. • Low-variability clusters exhibit limited reductions. • For low-variability customers, alternative policy instruments is well advised. • A model of discerning customer's demand response potential is suggested.

USA Withdrawal from Paris Agreement – What Next?

OpenAIRE

Sergey Chestnoy; Dinara Gershinkova

2017-01-01

In June 2017, President Trump announced the USA’s withdrawal from the Paris Climate Accord, which had been ratified for less than a year, thanks in large part to the USA. That drastic shift followed the change in residency at the White House. Withdrawing from the Paris Accord presents an interesting topic for analysis. There’s the practical side of the withdrawal procedure as set out in Article 28 of the agreement, not to mention the consequences of US non-participation in address...

Cocaine withdrawal causes delayed dysregulation of stress genes in the hippocampus.

Directory of Open Access Journals (Sweden)

M Julia García-Fuster

Full Text Available Relapse, even following an extended period of withdrawal, is a major challenge in substance abuse management. Delayed neurobiological effects of the drug during prolonged withdrawal likely contribute to sustained vulnerability to relapse. Stress is a major trigger of relapse, and the hippocampus regulates the magnitude and duration of stress responses. Recent work has implicated hippocampal plasticity in various aspects of substance abuse. We asked whether changes in stress regulatory mechanisms in the hippocampus may participate in the neuroadaptations that occur during prolonged withdrawal. We therefore examined changes in the rat stress system during the course of withdrawal from extended daily access (5-hours of cocaine self-administration, an animal model of addiction. Tissue was collected at 1, 14 and 28 days of withdrawal. Plasma corticosterone levels were determined and corticosteroid receptors (GR, MR, MR/GR mRNA ratios and expression of other stress-related molecules (HSP90AA1 and HSP90AB1 mRNA were measured in hippocampal subfields using in situ hybridization. Results showed a delayed emergence of dysregulation of stress genes in the posterior hippocampus following 28 days of cocaine withdrawal. This included increased GR mRNA in DG and CA3, increased MR and HSP90AA1 mRNA in DG, and decreased MR/GR mRNA ratio in DG and CA1. Corticosterone levels progressively decreased during the course of withdrawal, were normalized following 28 days of withdrawal, and were correlated negatively with GR and positively with MR/GR mRNA ratio in DG. These results suggest a role for the posterior hippocampus in the neuroadaptations that occur during prolonged withdrawal, and point to a signaling partner of GR, HSP90AA1, as a novel dysregulated target during cocaine withdrawal. These delayed neurobiological effects of extended cocaine exposure likely contribute to sustained vulnerability to relapse.

Simulated effects of groundwater withdrawals from the Kirkwood-Cohansey aquifer system and Piney Point aquifer, Maurice and Cohansey River Basins, Cumberland County and vicinity, New Jersey

Science.gov (United States)

Gordon, Alison D.; Buxton, Debra E.

2018-05-10

groundwater demand in 2050 at municipal public-supply wells; and (5) estimated 2050 monthly groundwater demand at municipal public-supply wells for which pumping of selected municipal public-supply wells was moved to a deeper part of the Kirkwood-Cohansey aquifer system. The results of the baseline scenario (scenario 1) were used for comparison with the results of scenarios 2‒5.The results of scenarios 2‒3 indicate that simulated water-level declines occurred in the Cohansey River Basin when full-allocation groundwater withdrawals were incorporated (scenarios 2 and 3). In scenarios 2 and 3, full-allocation withdrawals in the Cohansey River Basin were approximately 266 and 407 percent greater, respectively, than in the baseline scenario. In scenario 2, the largest decline in simulated water levels was more than 67 ft in June and September of scenario year 11, whereas in scenario 3, simulated water levels declined as much as 90 ft in June and more than 100 ft in September of scenario year 11. These simulated declines occurred in a small area around one pumped well in the Cohansey River Basin. The average decline in simulated water levels for this basin was less than 10 ft for scenario 2 and less than 20 ft for scenario 3. In scenario 2, the Menantico Creek subbasin in the Maurice River Basin had a decrease in base flow during about 29 percent of the 11-year simulation period, and in scenario 3, the decrease occurred during about 71 percent of the 11-year simulation period. In scenario 3, base flow in the Cohansey River Basin was less than the 7-day 10-year low flow in all months of simulation years 7 through 11. Several agricultural-irrigation wells and a number of public-supply wells are within the Cohansey River Basin and the Menantico Creek subbasin.Three additional scenarios were simulated to evaluate the possible use of the Piney Point aquifer in the Cumberland County study area using the New Jersey Regional Aquifer-System Analysis model, which incorporates all

Chronic agmatine treatment prevents behavioral manifestations of nicotine withdrawal in mice.

Science.gov (United States)

Kotagale, Nandkishor R; Chopde, Chandrabhan T; Umekar, Milind J; Taksande, Brijesh G

2015-05-05

Smoking cessation exhibits an aversive withdrawal syndrome characterized by both increases in somatic signs and affective behaviors including anxiety and depression. In present study, abrupt withdrawal of daily nicotine injections (2mg/kg, s.c., four times daily, for 10 days) significantly increased somatic signs viz. rearing, grooming, jumping, genital licking, leg licking, head shakes with associated depression (increased immobility in forced swim test) as well as anxiety (decreased the number of entries and time spent in open arm in elevated plus maze) in nicotine dependent animals. The peak effect was observed at 24h time point of nicotine withdrawal. Repeated administration of agmatine (40-80µg/mouse, i.c.v.) before the first daily dose of nicotine from day 5 to 10 attenuated the elevated scores of somatic signs and abolished the depression and anxiety like behavior induced by nicotine withdrawal in dependent animals. However, in separate groups, its acute administration 30min before behavior analysis of nicotine withdrawal was ineffective. This result clearly shows the role of agmatine in development of nicotine dependence and its withdrawal. In extension to behavioral experiments, brain agmatine analyses, carried out at 24h time point of nicotine withdrawal demonstrated marked decrease in basal brain agmatine concentration as compared to control animals. Taken together, these data support the role of agmatine as common biological substrate for somatic signs and affective symptoms of nicotine withdrawal. This data may project therapies based on agmatine in anxiety, depression and mood changes associated with tobacco withdrawal. Copyright © 2015 Elsevier B.V. All rights reserved.

Ketogenic Diet suppresses Alcohol Withdrawal Syndrome in Rats

DEFF Research Database (Denmark)

Dencker, Ditte; Molander, Anna; Thomsen, Morgane

2018-01-01

, we investigated the potential therapeutic benefit of a ketogenic diet in managing alcohol withdrawal symptoms during detoxification. METHODS: Male Sprague Dawley rats fed either ketogenic or regular diets were administered ethanol or water orally, twice daily for 6 days while the diet conditions were...... maintained. Abstinence symptoms were rated 6, 24, 48, and 72 hours after the last alcohol administration. RESULTS: Maintenance on a ketogenic diet caused a significant decrease in the alcohol withdrawal symptoms 'rigidity' and 'irritability'. CONCLUSION: Our preclinical pilot study suggests that a ketogenic...... diet may be a novel approach for treating alcohol withdrawal symptoms in humans. This article is protected by copyright. All rights reserved....

Emergence of dormant conditioned incentive approach by conditioned withdrawal in nicotine addiction.

Science.gov (United States)

Scott, Daniel; Hiroi, Noboru

2010-10-15

Nicotine is one of the determinants for the development of persistent smoking, and this maladaptive behavior is characterized by many symptoms, including withdrawal and nicotine seeking. The process by which withdrawal affects nicotine seeking is poorly understood. The impact of a withdrawal-associated cue on nicotine (.2 mg/kg)-conditioned place preference was assessed in male C57BL/6J mice (n = 8-17/group). To establish a cue selectively associated with withdrawal distinct from those associated with nicotine, a tone was paired with withdrawal in their home cages; mice were chronically exposed to nicotine (200 μg/mL for 15 days) from drinking water in their home cages and received the nicotinic acetylcholine receptor antagonist mecamylamine (2.5 mg/kg) to precipitate withdrawal in the presence of a tone. The effect of the withdrawal-associated tone on nicotine-conditioned place preference was then evaluated in the place-conditioning apparatus after a delay, when nicotine-conditioned place preference spontaneously disappeared. A cue associated with precipitated withdrawal reactivated the dormant effect of nicotine-associated cues on conditioned place preference. This effect occurred during continuous exposure to nicotine but not during abstinence. A conditioned withdrawal cue could directly amplify the incentive properties of cues associated with nicotine. This observation extends the contemporary incentive account of the role of withdrawal in addiction to cue-cue interaction. Copyright © 2010 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.

The impacts of China’s household consumption expenditure patterns on energy demand and carbon emissions towards 2050

International Nuclear Information System (INIS)

Dai, Hancheng; Masui, Toshihiko; Matsuoka, Yuzuru; Fujimori, Shinichiro

2012-01-01

This paper explores how China’s household consumption patterns over the period 2005–2050 influence the total energy demand and carbon dioxide (CO 2 ) emissions in two baseline scenarios, and how it influences carbon prices as well as the economic cost in the corresponding carbon mitigation scenarios. To this end we first put forward two possible household consumption expenditure patterns up to 2050 using the Working–Leser model, taking into account total expenditure increase and urbanization. For comparison, both expenditure patterns are then incorporated in a hybrid recursive dynamic computable general equilibrium model. The results reveal that as income level increases in the coming decades, the direct and indirect household energy requirements and CO 2 emissions would rise drastically. When household expenditure shifts from material products and transport to service-oriented goods, around 21,000 mtce of primary energy and 45 billion tons of CO 2 emissions would be saved over the 45-year period from 2005 to 2050. Moreover, carbon prices in the dematerialized mitigation scenario would fall by 13% in 2050, thus reducing the economic cost. - Highlights: ► Propose two household expenditure patterns considering income rise and urbanization. ► Much energy and CO 2 emissions would be saved in low-carbon consumption scenario. ► Carbon prices would reduce a lot in low-carbon consumption scenario.

Time-course of the DSM-5 cannabis withdrawal symptoms in poly-substance abusers

DEFF Research Database (Denmark)

Hesse, Morten; Thylstrup, Birgitte

2013-01-01

Background Evidence is accumulating that a cannabis withdrawal syndrome is common, of clinical significance, and has a clear time course. Up till now, very limited data exist on the cannabis withdrawal symptoms in patients with co-morbid substance use disorders, other than cannabis use and tobacco...... the DSM-5 Withdrawal Symptom Check List with withdrawal symptoms from all classes of substances, with no indication that the described symptoms should be attributed to withdrawal. Self-reported time since last use of cannabis was used as a predictor of cannabis withdrawal severity. Results...... With the exception of loss of appetite, time since last use of cannabis was associated with all types of withdrawal symptoms listed in the DSM-5. Only four of 19 symptoms intended to measure withdrawal from other substances were related to time since last use of cannabis, including vivid, unpleasant dreams...

Tolerance and withdrawal from prolonged opioid use in critically ill children.

Science.gov (United States)

Anand, Kanwaljeet J S; Willson, Douglas F; Berger, John; Harrison, Rick; Meert, Kathleen L; Zimmerman, Jerry; Carcillo, Joseph; Newth, Christopher J L; Prodhan, Parthak; Dean, J Michael; Nicholson, Carol

2010-05-01

After prolonged opioid exposure, children develop opioid-induced hyperalgesia, tolerance, and withdrawal. Strategies for prevention and management should be based on the mechanisms of opioid tolerance and withdrawal. Relevant manuscripts published in the English language were searched in Medline by using search terms "opioid," "opiate," "sedation," "analgesia," "child," "infant-newborn," "tolerance," "dependency," "withdrawal," "analgesic," "receptor," and "individual opioid drugs." Clinical and preclinical studies were reviewed for data synthesis. Mechanisms of opioid-induced hyperalgesia and tolerance suggest important drug- and patient-related risk factors that lead to tolerance and withdrawal. Opioid tolerance occurs earlier in the younger age groups, develops commonly during critical illness, and results more frequently from prolonged intravenous infusions of short-acting opioids. Treatment options include slowly tapering opioid doses, switching to longer-acting opioids, or specifically treating the symptoms of opioid withdrawal. Novel therapies may also include blocking the mechanisms of opioid tolerance, which would enhance the safety and effectiveness of opioid analgesia. Opioid tolerance and withdrawal occur frequently in critically ill children. Novel insights into opioid receptor physiology and cellular biochemical changes will inform scientific approaches for the use of opioid analgesia and the prevention of opioid tolerance and withdrawal.

A double blind, within subject comparison of spontaneous opioid withdrawal from buprenorphine versus morphine.

Science.gov (United States)

Tompkins, D Andrew; Smith, Michael T; Mintzer, Miriam Z; Campbell, Claudia M; Strain, Eric C

2014-02-01

Preliminary evidence suggests that there is minimal withdrawal after the cessation of chronically administered buprenorphine and that opioid withdrawal symptoms are delayed compared with those of other opioids. The present study compared the time course and magnitude of buprenorphine withdrawal with a prototypical μ-opioid agonist, morphine. Healthy, out-of-treatment opioid-dependent residential volunteers (N = 7) were stabilized on either buprenorphine (32 mg/day i.m.) or morphine (120 mg/day i.m.) administered in four divided doses for 9 days. They then underwent an 18-day period of spontaneous withdrawal, during which four double-blind i.m. placebo injections were administered daily. Stabilization and spontaneous withdrawal were assessed for the second opioid using the same time course. Opioid withdrawal measures were collected eight times daily. Morphine withdrawal symptoms were significantly (P withdrawal as measured by mean peak ratings of Clinical Opiate Withdrawal Scale (COWS), Subjective Opiate Withdrawal Scale (SOWS), all subscales of the Profile of Mood States (POMS), sick and pain (0-100) Visual Analog Scales, systolic and diastolic blood pressure, heart rate, respiratory rate, and pupil dilation. Peak ratings on COWS and SOWS occurred on day 2 of morphine withdrawal and were significantly greater than on day 2 of buprenorphine withdrawal. Subjective reports of morphine withdrawal resolved on average by day 7. There was minimal evidence of buprenorphine withdrawal on any measure. In conclusion, spontaneous withdrawal from high-dose buprenorphine appears subjectively and objectively milder compared with that of morphine for at least 18 days after drug cessation.

Bulimic symptoms and the social withdrawal syndrome.

Science.gov (United States)

Rotenberg, Ken J; Bharathi, Carla; Davies, Helen; Finch, Tom

2013-08-01

One hundred and thirty-seven undergraduates (81 females; mean age = 21 years-10 months) completed the Bulimic SEDS subscale and standardized measures of trust beliefs in close others (mother, father, and friend), disclosure to them, and loneliness. Structural Equation Modelling yielded: (1) a negative path between Bulimic Symptoms and trust beliefs, (2) a positive path between trust beliefs and disclosure, (3) a negative path between trust beliefs and loneliness, and (4) a negative path between disclosure and loneliness. As expected, trust beliefs statistically mediated the relations between Bulimic Symptoms and both disclosure and loneliness and disclosure statistically mediated the relation between trust beliefs and loneliness. The findings supported the conclusion that individuals with bulimia nervosa are prone to the social withdrawal syndrome comprising a coherent and integrated pattern of low trust beliefs in close others, low disclosure to close others, and high loneliness. Copyright © 2013 Elsevier Ltd. All rights reserved.

Capturing well-being in activity pattern models within activity-based travel demand models.

Science.gov (United States)

2013-04-01

The activity-based approach which is based on the premise that the demand for travel is derived : from the demand for activities, currently constitutes the state of the art in metropolitan travel : demand forecasting and particularly in a form known ...

The Study of the Role of Contributor Factors in Addiction Withdrawal

Directory of Open Access Journals (Sweden)

Omar Kianipour

2012-08-01

Full Text Available Introduction: The present paper investigated the factors contributing to addiction withdrawal so as to it would be possible to set preventive and rehabilitative programs for addicts. Method: The study was ex-post facto and causal-comparative one. Population included all addicts referred to addiction withdrawal centers of Kahnouj city and the sample was selected of addicts of Yaran addiction withdrawal Center by voluntary sampling. Bar-on emotional intelligence inventory, family boundary questionnaire and demographic information were administered among selected sample. Results: The results showed that normal family boundaries, higher emotional intelligence and opium use in comparison of crack and crystal glass are effective on addiction withdrawal. But disengaged family boundaries, crack and crystal glass use can be led to addiction recursion. Age, addiction duration, marital status, and education level are not effective on addiction withdrawal. Conclusion: Altogether, the results represented the role and importance of variables namely: family, emotional intelligence, and the kind of used material in addiction withdrawal.

20 CFR 410.232 - Withdrawal of a claim.

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Withdrawal of a claim. 410.232 Section 410.232 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL COAL MINE HEALTH AND SAFETY ACT OF 1969... Claims and Evidence § 410.232 Withdrawal of a claim. (a) Before adjudication of claim. A claimant (or an...

12 CFR 563g.11 - Withdrawal or abandonment.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Withdrawal or abandonment. 563g.11 Section 563g.11 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY SECURITIES OFFERINGS § 563g.11 Withdrawal or abandonment. (a) Any offering circular, amendment, or exhibit may be withdrawn...

27 CFR 19.997 - Withdrawal of fuel alcohol.

Science.gov (United States)

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Withdrawal of fuel alcohol. 19.997 Section 19.997 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU... and Transfers § 19.997 Withdrawal of fuel alcohol. For each shipment or other removal of fuel alcohol...

Dental family stress and coping patterns.

Science.gov (United States)

Nevin, R S; Sampson, V M

1986-10-01

This exploratory study of 28 married male dentists and their families was designed to gain an understanding about the stressors that dentists and their spouses experience, the life events and family strains they incur, the behavioral coping patterns they utilize, and their psychosocial characteristics. The study found that although stable dental families did encounter a significant number of stressors arising from both the dental practice and the family, they maintained their sense of balance through strong family coping skills and family resources. The effect of the dentist's office-related stress was directly felt in the family, especially by the spouse. Strong coping patterns resulted when dentists and spouses maintained a balance of time and responsibility, satisfaction in work and family activity, regular communication, sharing of decision making, good physical health, and the inclusion of an active exercise program within multiple demands on their time.

Application of spinal code for performance improvement in free-space optical communications

Science.gov (United States)

Saiki, Naoya; Okamoto, Eiji; Takenaka, Hideki; Toyoshima, Morio

2017-09-01

In recent years, the demand for high-capacity communication has grown, and fiber-optic transmission is being used in wired communications to meet this demand. Similarly, free-space optics (FSO), which is an optical wireless communication technology that uses laser light, has attracted much attention and has been considered as a suitable alternative to satisfy this demand in wireless communications. Free-space optical communication uses a hundred THz frequency band and allows for high-speed and radio-regulation free transmission, which may provide a solution for the current shortage of radio frequency bands.

Indirect pathways between depressive symptoms and marital distress: the role of conflict communication, attributions, and attachment style.

Science.gov (United States)

Heene, Els L D; Buysse, Ann; Van Oost, Paulette

2005-12-01

Previous studies have focused on concomitants of depression and marital distress in order to help explain the relationship between the two, suggesting that several variables, such as conflict communication, attributions, and attachment style, are associated with depression, marital distress, or both. Our contention is that the selected variables may be important mediators (hypothesis 1) or moderators (hypothesis 2) of the concomitance between depression and marital adjustment, exploring the direct and indirect ways in which depressive symptoms and marital adjustment are related. In total, 415 heterosexual couples were recruited, and a series of regression analyses was conducted to test our hypotheses separately for men and women. Results indicated that demand-withdrawal, avoidance, causal attributions, and secure, ambivalent, and avoidant attachment mediated the relation between depressive symptoms and marital adjustment in the female sample, whereas constructive communication and causal and responsible attributions were significant mediators of men's levels of depressive symptoms and marital adjustment. In addition, avoidance and secure attachment moderated the association between depressive symptoms and marital adjustment in the female sample, and causal attributions were significant moderators of the association between depressive symptoms and marital adjustment for men. Several conclusions and implications for theory and future research are discussed.

Affective communication in rodents: ultrasonic vocalizations as a tool for research on emotion and motivation.

Science.gov (United States)

Wöhr, Markus; Schwarting, Rainer K W

2013-10-01

Mice and rats emit and perceive calls in the ultrasonic range, i.e., above the human hearing threshold of about 20 kHz: so-called ultrasonic vocalizations (USV). Juvenile and adult rats emit 22-kHz USV in aversive situations, such as predator exposure and fighting or during drug withdrawal, whereas 50-kHz USV occur in appetitive situations, such as rough-and-tumble play and mating or in response to drugs of abuse, e.g., amphetamine. Aversive 22-kHz USV and appetitive 50-kHz USV serve distinct communicative functions. Whereas 22-kHz USV induce freezing behavior in the receiver, 50-kHz USV lead to social approach behavior. These opposite behavioral responses are paralleled by distinct patterns of brain activation. Freezing behavior in response to 22-kHz USV is paralleled by increased neuronal activity in brain areas regulating fear and anxiety, such as the amygdala and periaqueductal gray, whereas social approach behavior elicited by 50-kHz USV is accompanied by reduced activity levels in the amygdala but enhanced activity in the nucleus accumbens, a brain area implicated in reward processing. These opposing behavioral responses, together with distinct patterns of brain activation, particularly the bidirectional tonic activation or deactivation of the amygdala elicited by 22-kHz and 50-kHz USV, respectively, concur with a wealth of behavioral and neuroimaging studies in humans involving emotionally salient stimuli, such as fearful and happy facial expressions. Affective ultrasonic communication therefore offers a translational tool for studying the neurobiology underlying socio-affective communication. This is particularly relevant for rodent models of neurodevelopmental disorders characterized by social and communication deficits, such as autism and schizophrenia.

Seven Trends Driving U.S. Food Demands

OpenAIRE

Kinsey, Jean D.

1992-01-01

Seven trends have a great deal to say about how demand for food will evolve into the 21 st century. They relate to the slow growth in total food demand, diversity in foods, global homogenization of food consumption patterns, demand for convenience, public services related to food, relationships between food production and its distribution to the environment, and, better health. Paying close attention to these factors can help distinguish between fads that will soon be gone and more fundamenta...

Psychosocial withdrawal characteristics of nicotine compared with alcohol and caffeine.

Science.gov (United States)

Miyata, Hisatsugu; Hironaka, Naoyuki; Takada, Kohji; Miyasato, Katsumasa; Nakamura, Koichi; Yanagita, Tomoji

2008-10-01

The purpose of the present study was to observe the psychosocial characteristics of withdrawal from cigarette smoking in comparison with those from caffeine (CAF) and alcoholic (ALC) beverage withdrawal. Twenty-seven healthy volunteers at a medial level of dependence on both cigarettes (nicotine, NCT) and either CAF or ALC, as judged by the DSM-IV-TR criteria for substance dependence, participated in this study. The participants were required to abstain from smoking and either CAF or ALC for 7 days, each one after another, with a 7-day interval. The order of abstinence was counterbalanced among the participants. Psychosocial parameters, including a desire for substances, social activity function, well-being, withdrawal symptoms, and vital signs, were assessed during the withdrawal periods. The study protocol was approved by the Jikei University Review Board. The results indicated that there were no differences in the maximum level of desire for a substance and the influence on social activity function between NCT and other substances during the withdrawal periods. As for withdrawal symptoms, NCT caused a more intensive degree of irritability than CAF or ALC, and a more intensive degree of difficulty concentrating and restlessness than did withdrawal from ALC. However, the subjective well-being questionnaire indicated no differences in these symptoms between NCT and other substances. The present results suggest that there are no significant differences in psychosocial manifestations regarding the difficulty in abstaining from NCT, CAF, and ALC.

Communication, the cornerstone of organizational life: business communication tools used by Portuguese companies

OpenAIRE

Simões, Anabela Valente; Dimas, Isabel Dórdio; Calvão, Ana Rita

2016-01-01

As a dynamic, complex and multidimensional human process, communication implies a social relation based on which subjects share a certain meaning. Bearing in mind that each social system in which subjects interact is founded and developed through communicational acts, communication is also, therefore, the core of organizational life, both in its endogenous and exogenous dimension. Without communication, there isn’t organization, management, cooperation, motivation, sales, offer and demand, ma...

The Treatment of Clozapine-Withdrawal Delirium with Electroconvulsive Therapy

Directory of Open Access Journals (Sweden)

Anish Modak

2017-01-01

Full Text Available Clozapine, a commonly used atypical antipsychotic, can precipitate a severe withdrawal syndrome. In this report, we describe a case of delirium with catatonic features emerging after the immediate cessation of clozapine subsequent to concerns of developing neuroleptic malignant syndrome. After multiple treatments were found to be inefficacious, electroconvulsive therapy (ECT was initiated, resulting in significant improvement. A literature search revealed six previous cases of clozapine-withdrawal syndromes of varied symptomatology treated with ECT. To our knowledge, the present case represents the first reported clozapine-withdrawal delirium treated successfully with ECT.

Youth social withdrawal behavior (hikikomori): A systematic review of qualitative and quantitative studies.

Science.gov (United States)

Li, Tim M H; Wong, Paul W C

2015-07-01

Acute and/or severe social withdrawal behavior among youth was seen as a culture-bound psychiatric syndrome in Japan, but more youth social withdrawal cases in different countries have been discovered recently. However, due to the lack of a formal definition and diagnostic tool for youth social withdrawal, cross-cultural observational and intervention studies are limited. We aimed to consolidate existing knowledge in order to understand youth social withdrawal from diverse perspectives and suggest different interventions for different trajectories of youth social withdrawal. This review examined the current available scientific information on youth social withdrawal in the academic databases: ProQuest, ScienceDirect, Web of Science and PubMed. We included quantitative and qualitative studies of socially withdrawn youths published in English and academic peer-reviewed journals. We synthesized the information into the following categories: (1) definitions of youth social withdrawal, (2) developmental theories, (3) factors associated with youth social withdrawal and (4) interventions for socially withdrawn youths. Accordingly, there are diverse and controversial definitions for youth social withdrawal. Studies of youth social withdrawal are based on models that lead to quite different conclusions. Researchers with an attachment perspective view youth social withdrawal as a negative phenomenon, whereas those who adopt Erikson's developmental theory view it more positively as a process of seeking self-knowledge. Different interventions for socially withdrawn youths have been developed, mainly in Japan, but evidence-based practice is almost non-existent. We propose a theoretical framework that views youth social withdrawal as resulting from the interplay between psychological, social and behavioral factors. Future validation of the framework will help drive forward advances in theory and interventions for youth social withdrawal as an emerging issue in developed

The Comparison of Relationship between Family Communication Patterns and Self Concept with Coping Styles in Male and Female Students

Directory of Open Access Journals (Sweden)

R Taheri

2012-10-01

Full Text Available Background & Aim: Since people have different coping styles, the purpose of the present research was to compare the relationship between family communication patterns and self-concept with coping styles among male and female students of Eram Higher Education Institution in Shiraz. Methods: In the present correlation study conducted in 2011 at Eram Higher Education Institution in Shiraz, 229 participants (91 males &119 females were selected by simple random sampling method. Data was collected by using the revised version of family communication patterns questionnaire (RFCP, Koerner & Fitz patrik (2002, Beck's Self-concept Test (CST (1990 and Coping Inventory for Stressful Situations (CISS Endler & Parker (1990. Data was analyzed using correlation matrix & independent t-test analysis. Results: According to the result, there was significant correlation between family communication patterns and self-concept with coping styles among male and female students. In the female group, task oriented coping and avoidance oriented coping with conversation orientation and emotion oriented coping with conforming orientation showed positive significant correlation. In male group avoidance orientation coping with conversation orientation and emotion oriented coping with conforming orientation showed positive significant correlation. Also, related to self concept variable, results showed female students task oriented coping and avoidance oriented coping had significant correlation with the self concept variable, but the male students avoidance oriented coping had significant correlation with the self concept variable(P<0/05. Also, the result showed significant difference between two male and female students, in emotion oriented coping, so the female group, emotion oriented coping with (51/48 was more than the orientation within the male group with (48/18, (p<0.05. Conclusion: Family communication patterns and the concept are effective on coping styles. Therefore

Smartphone Restriction and its Effect on Subjective Withdrawal Related Scores

OpenAIRE

Aarestad, Sarah Helene; Eide, Tine Almenning

2017-01-01

Smartphone overuse is associated with a number of negative consequences for the individual and the environment. In the right end of the distribution of smartphone usage, concepts such as smartphone addiction seem warranted. An area that so far lacks research concerns the effect of smartphone restriction generally and specifically on subjective withdrawal related scores across different degrees of smartphone usage. The present study examined withdrawal related scores on the Smartphone Withdraw...

Comparison of parent-child communication patterns and parental role satisfaction among mothers with and without breast cancer.

Science.gov (United States)

Cho, Ok-Hee; Yoo, Yang-Sook; Hwang, Kyung-Hye

2015-05-01

This study compared parent-child communication (PCC) patterns and parental role satisfaction (PRS) between women with breast cancer and healthy women. A limited number of studies have examined PCC and the impact of PRS between cancer patients and their children. It was a descriptive survey design comprising the Parent-Adolescent Communication Scale and a PRS measure. Data from 202 participants in total were analysed with two-way analyses of variance and t-tests. Closed communication was higher in both groups than open communication, but higher still in children of women with breast cancer than in children of healthy women. PRS was lower in women with breast cancer than in healthy women. Educational programs should be developed to support parents and children during the post-treatment adjustment period for mothers with breast cancer. Such programs should take a practical approach toward increasing open parent-child communication while considering personal characteristics and cultural backgrounds. Copyright © 2014 Elsevier Inc. All rights reserved.

Communication Techniques for Individual and Organizational Coping with Job Burnout.

Science.gov (United States)

Cronin, Michael

This paper reviews the literature on the causes of job burnout, a condition which has been linked with high personnel turnover, friction with co-workers and supervisors, increased dissatisfaction with both the job and the organization, job withdrawal, decreased productivity and absenteeism. The paper discusses the communication skills necessary to…

78 FR 12702 - Control of Communicable Diseases: Foreign; Scope and Definitions

Science.gov (United States)

2013-02-25

... Control of Communicable Diseases: Foreign; Scope and Definitions AGENCY: Centers for Disease Control and...; withdrawal. SUMMARY: The Centers for Disease Control and Prevention (CDC) within the Department of Health and... solicited public comment on updates to the Scope and Definitions for its regulations. DATES: The Notice of...

Conceptual framework for load controlling : with demand reduction bidding & consumer retention

NARCIS (Netherlands)

Babar, M.; Ahamed, I.; Al-Ammar, E.A.

2013-01-01

Advancement in demand side management strategies enables smart grid to cope with the increasing energy demand and provide economic benefit to all of its stakeholders. Moreover, emerging concept of smart pricing and advances in load control and communication generate new business opportunities as a

The acute tobacco withdrawal syndrome among black smokers.

Science.gov (United States)

Robinson, Cendrine D; Pickworth, Wallace B; Heishman, Stephen J; Waters, Andrew J

2014-03-01

Black smokers have greater difficulty quitting tobacco than White smokers, but the mechanisms underlying between-race differences in smoking cessation are not clear. One possibility is that Black smokers experience greater acute withdrawal than Whites. We investigated whether Black (n = 104) and White smokers (n = 99) differed in abstinence-induced changes in self-report, physiological, and cognitive performance measures. Smokers not wishing to quit completed two counterbalanced experimental sessions. Before one session, they abstained from smoking for at least 12 hr. They smoked normally before the other session. Black smokers reported smaller abstinence-induced changes on a number of subjective measures including the total score of the 10-item Questionnaire for Smoking Urges (QSU) and the total score of the Wisconsin Smoking Withdrawal Scale (WSWS). However, on most subjective measures, and on all objective measures, there were no between-race differences in abstinence-induced change scores. Moreover, Black participants did not report lower QSU and WSWS ratings at the abstinent session, but they did experience significantly higher QSU and WSWS ratings at the nonabstinent session. Abstinence-induced changes in subjective, physiological, and cognitive measures in White smokers were similar for smokers of nonflavored and menthol-flavored cigarettes. There was no evidence that Black smokers experienced greater acute tobacco withdrawal than Whites. To the contrary, Black participants experienced smaller abstinence-induced changes in self-reported craving and withdrawal on some measures. Racial differences in smoking cessation are unlikely to be explained by acute withdrawal.

5 CFR 831.1207 - Withdrawal of disability retirement applications.

Science.gov (United States)

2010-01-01

... type. (d) OPM also considers a disability retirement application to be withdrawn when the agency... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Withdrawal of disability retirement...) CIVIL SERVICE REGULATIONS (CONTINUED) RETIREMENT Disability Retirement § 831.1207 Withdrawal of...

Opioid withdrawal signs and symptoms in children: frequency and determinants.

Science.gov (United States)

Fisher, Deborah; Grap, Mary Jo; Younger, Janet B; Ameringer, Suzanne; Elswick, R K

2013-01-01

The purpose of this study was to, in a pediatric population, describe the frequency of opioid withdrawal signs and symptoms and to identify factors associated with these opioid withdrawal signs and symptoms. Opioids are used routinely in the pediatric intensive care population for analgesia, sedation, blunting of physiologic responses to stress, and safety. In children, physical dependence may occur in as little as 2-3 days of continuous opioid therapy. Once the child no longer needs the opioid, the medications are reduced over time. A prospective, descriptive study was conducted. The sample of 26 was drawn from all patients, ages 2 weeks to 21 years admitted to the Children's Hospital of Richmond pediatric intensive care unit (PICU) and who have received continuous infusion or scheduled opioids for at least 5 days. Data collected included: opioid withdrawal score (WAT-1), opioid taper rate (total dose of opioid per day in morphine equivalents per kilogram [MEK]), pretaper peak MEK, pretaper cumulative MEK, number of days of opioid exposure prior to taper, and age. Out of 26 enrolled participants, only 9 (45%) had opioid withdrawal on any given day. In addition, there was limited variability in WAT-1 scores. The most common symptoms notes were diarrhea, vomit, sweat, and fever. For optimal opioid withdrawal assessments, clinicians should use a validated instrument such as the WAT-1 to measure for signs and symptoms of opioid withdrawal. Further research is indicated to examine risk factors for opioid withdrawal in children. Copyright © 2013 Elsevier Inc. All rights reserved.

Communication Patterns and Intellectual Teamwork.

Science.gov (United States)

Galegher, Jolene

1992-01-01

Finds that both experienced scientists and college students found it difficult to carry out intellectual teamwork involving collaboratively authored documents without the interactivity and expressiveness permitted by face-to-face communication. (SR)

ADHD symptoms impact smoking outcomes and withdrawal in response to Varenicline treatment for smoking cessation.

Science.gov (United States)

Bidwell, L Cinnamon; Karoly, Hollis C; Hutchison, Kent E; Bryan, Angela D

2017-10-01

Attention-Deficit/Hyperactivity Disorder (ADHD) is associated with nicotine dependence and difficulty quitting smoking. Few cessation trials specifically consider the impact of ADHD on treatment outcomes, including those testing established pharmacological therapies, such as varenicline. The current study focused on the impact of pretreatment ADHD inattention (IN) and hyperactivity-impulsivity (HI) symptoms on treatment outcome in a randomized controlled trial of varenicline [N=205, average age=34.13(10.07), average baseline cigarettes per day=14.71(7.06)]. Given that varenicline's putative therapeutic mechanism is attenuation of withdrawal severity during abstinence, we also tested changes in withdrawal as a mediator of treatment effects in high and low ADHD groups. ADHD symptom severity in this sample was in the subclinical range. Cessation was associated with HI, but not IN, such that high HI individuals on varenicline reported the lowest smoking levels at the end of treatment across all groups (3.06cig/day for high HI vs 4.02cig/day for low HI). Individuals with high HI who received placebo had the highest smoking at the end of treatment (7.69cigs/day for high HI vs 5.56cig/day for low HI). Patterns continued at follow-up. Varenicline significantly reduced withdrawal for those with high HI, but not low HI. However, path models did not support an indirect effect of medication on reducing smoking via withdrawal in either group, suggesting that unmeasured variables are involved in varenicline's effect on reducing smoking. These data add to a gap in the smoking cessation literature regarding the impact of ADHD symptoms on the efficacy and mechanisms of frontline pharmacological treatments. Copyright © 2017 Elsevier B.V. All rights reserved.

Network analysis of team communication in a busy emergency department

Science.gov (United States)

2013-01-01

Background The Emergency Department (ED) is consistently described as a high-risk environment for patients and clinicians that demands colleagues quickly work together as a cohesive group. Communication between nurses, physicians, and other ED clinicians is complex and difficult to track. A clear understanding of communications in the ED is lacking, which has a potentially negative impact on the design and effectiveness of interventions to improve communications. We sought to use Social Network Analysis (SNA) to characterize communication between clinicians in the ED. Methods Over three-months, we surveyed to solicit the communication relationships between clinicians at one urban academic ED across all shifts. We abstracted survey responses into matrices, calculated three standard SNA measures (network density, network centralization, and in-degree centrality), and presented findings stratified by night/day shift and over time. Results We received surveys from 82% of eligible participants and identified wide variation in the magnitude of communication cohesion (density) and concentration of communication between clinicians (centralization) by day/night shift and over time. We also identified variation in in-degree centrality (a measure of power/influence) by day/night shift and over time. Conclusions We show that SNA measurement techniques provide a comprehensive view of ED communication patterns. Our use of SNA revealed that frequency of communication as a measure of interdependencies between ED clinicians varies by day/night shift and over time. PMID:23521890

U.S. withdrawal from the Paris Agreement: Reasons, impacts, and China's response

OpenAIRE

Hai-Bin Zhang; Han-Cheng Dai; Hua-Xia Lai; Wen-Tao Wang

2017-01-01

Applying qualitative and quantitative methods, this article explains the driving forces behind U.S. President Donald Trump's decision to withdraw from the Paris Agreement, assesses the impacts of this withdrawal on the compliance prospects of the agreement, and proposes how China should respond. The withdrawal undercuts the foundation of global climate governance and upsets the process of climate cooperation, and the impacts are manifold. The withdrawal undermines the universality of the Pari...

Opportunities, Barriers and Actions for Industrial Demand Response in California

Energy Technology Data Exchange (ETDEWEB)

McKane, Aimee T.; Piette, Mary Ann; Faulkner, David; Ghatikar, Girish; Radspieler Jr., Anthony; Adesola, Bunmi; Murtishaw, Scott; Kiliccote, Sila

2008-01-31

In 2006 the Demand Response Research Center (DRRC) formed an Industrial Demand Response Team to investigate opportunities and barriers to implementation of Automated Demand Response (Auto-DR) systems in California industries. Auto-DR is an open, interoperable communications and technology platform designed to: Provide customers with automated, electronic price and reliability signals; Provide customers with capability to automate customized DR strategies; Automate DR, providing utilities with dispatchable operational capability similar to conventional generation resources. This research began with a review of previous Auto-DR research on the commercial sector. Implementing Auto-DR in industry presents a number of challenges, both practical and perceived. Some of these include: the variation in loads and processes across and within sectors, resource-dependent loading patterns that are driven by outside factors such as customer orders or time-critical processing (e.g. tomato canning), the perceived lack of control inherent in the term 'Auto-DR', and aversion to risk, especially unscheduled downtime. While industry has demonstrated a willingness to temporarily provide large sheds and shifts to maintain grid reliability and be a good corporate citizen, the drivers for widespread Auto-DR will likely differ. Ultimately, most industrial facilities will balance the real and perceived risks associated with Auto-DR against the potential for economic gain through favorable pricing or incentives. Auto-DR, as with any ongoing industrial activity, will need to function effectively within market structures. The goal of the industrial research is to facilitate deployment of industrial Auto-DR that is economically attractive and technologically feasible. Automation will make DR: More visible by providing greater transparency through two-way end-to-end communication of DR signals from end-use customers; More repeatable, reliable, and persistent because the automated

Addressing Energy Demand through Demand Response. International Experiences and Practices

Energy Technology Data Exchange (ETDEWEB)

Shen, Bo [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Ghatikar, Girish [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Ni, Chun Chun [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Dudley, Junqiao [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Martin, Phil [Enernoc, Inc., Boston, MA (United States); Wikler, Greg

2012-06-01

Demand response (DR) is a load management tool which provides a cost-effective alternative to traditional supply-side solutions to address the growing demand during times of peak electrical load. According to the US Department of Energy (DOE), demand response reflects “changes in electric usage by end-use customers from their normal consumption patterns in response to changes in the price of electricity over time, or to incentive payments designed to induce lower electricity use at times of high wholesale market prices or when system reliability is jeopardized.” 1 The California Energy Commission (CEC) defines DR as “a reduction in customers’ electricity consumption over a given time interval relative to what would otherwise occur in response to a price signal, other financial incentives, or a reliability signal.” 2 This latter definition is perhaps most reflective of how DR is understood and implemented today in countries such as the US, Canada, and Australia where DR is primarily a dispatchable resource responding to signals from utilities, grid operators, and/or load aggregators (or DR providers).

Phenobarbital compared to benzodiazepines in alcohol withdrawal treatment

DEFF Research Database (Denmark)

Askgaard, Gro; Hallas, Jesper; Fink-Jensen, Anders

2016-01-01

BACKGROUND: Long-acting benzodiazepines such as chlordiazepoxide are recommended as first-line treatment for alcohol withdrawal. These drugs are known for their abuse liability and might increase alcohol consumption among problem drinkers. Phenobarbital could be an alternative treatment option......, possibly with the drawback of a more pronounced acute toxicity. We evaluated if phenobarbital compared to chlordiazepoxide decreased the risk of subsequent use of benzodiazepines, alcohol recidivism and mortality. METHODS: The study was a register-based cohort study of patients admitted for alcohol...... withdrawal 1998-2013 and treated with either phenobarbital or chlordiazepoxide. Patients were followed for one year. We calculated hazard ratios (HR) for benzodiazepine use, alcohol recidivism and mortality associated with alcohol withdrawal treatment, while adjusting for confounders. RESULTS: A total...

Devising a New Model of Demand-Based Learning Integrated with Social Networks and Analyses of its Performance

Directory of Open Access Journals (Sweden)

Bekim Fetaji

2018-02-01

Full Text Available The focus of the research study is to devise a new model for demand based learning that will be integrated with social networks such as Facebook, twitter and other. The study investigates this by reviewing the published literature and realizes a case study analyses in order to analyze the new models’ analytical perspectives of practical implementation. The study focuses on analyzing demand-based learning and investigating how it can be improved by devising a specific model that incorporates social network use. Statistical analyses of the results of the questionnaire through research of the raised questions and hypothesis showed that there is a need for introducing new models in the teaching process. The originality stands on the prologue of the social login approach to an educational environment, whereas the approach is counted as a contribution of developing a demand-based web application, which aims to modernize the educational pattern of communication, introduce the social login approach, and increase the process of knowledge transfer as well as improve learners’ performance and skills. Insights and recommendations are provided, argumented and discussed.

A characterization of the current communication patterns in Danish community pharmacies - an observational study.

Science.gov (United States)

Kaae, Susanne; Mygind, Anna; Saleem, Sahdia

2013-01-01

Community pharmacies have been trying to expand their core function by counseling customers at the counter. This has been challenging given that customers' interest in receiving counseling may be limited. To characterize the current pharmacist-customer communication patterns to inform future studies and models of communication. Non-participant structured observations based on the works of Stevenson et al. were conducted. A random selection of one hundred encounters in five pharmacies in Denmark was obtained. Type of encounter, type of medicine purchased and the age and gender of the customer were observed, and associations between the parameters identified. Customers initiated 13% of the dialogs, whereas 60% were initiated by the staff (with 38% of the customers declining the offer). 26% of the encounters saw no communication about the medicine. The customers' level of interest in counseling varied significantly and more with the type of medicine purchased than the level of encouragement from the staff to initiate a dialog. The customers' interest in dialog, in contrast with the staff behavior, depended significantly on age and gender. Customers' interest in counseling varies significantly. Pharmacy staff should take this into consideration when trying to optimize communication. Copyright © 2013 Elsevier Inc. All rights reserved.

Multichannel pension communication : An integrated perspective on policies, practices, and literacy demands

NARCIS (Netherlands)

Nell, M.L.

2017-01-01

The design of pension communication environments often leaves to be desired. This is partly due to pension communication legislation, which communication professionals often find difficult to interpret and to comply with. Out of discontent with the legally required media, many pension organizations

Lessons Learned : Communication studies in transition

NARCIS (Netherlands)

drs. Korien van Vuuren - Verkerk; dr. ir. J. (Jan) van der Stoep

2018-01-01

Jobs of communication professionals are closely linked to transformations in society and therefore the role of these professionals is changing rapidly. Communication students must be prepared for the new demands put on communication professionals in the field. In Ede, a new curriculum in

Probabilistic Quantification of Potentially Flexible Residential Demand

DEFF Research Database (Denmark)

Kouzelis, Konstantinos; Mendaza, Iker Diaz de Cerio; Bak-Jensen, Birgitte

2014-01-01

The balancing of power systems with high penetration of renewable energy is a serious challenge to be faced in the near future. One of the possible solutions, recently capturing a lot of attention, is demand response. Demand response can only be achieved by power consumers holding loads which allow...... them to modify their normal power consumption pattern, namely flexible consumers. However flexibility, despite being constantly mentioned, is usually not properly defined and even rarer quantified. This manuscript introduces a methodology to identify and quantify potentially flexible demand...

75 FR 12804 - Withdrawal of Regulatory Guide 8.6

Science.gov (United States)

2010-03-17

... ``Regulatory Guides'' in the NRC's Electronic Reading Room at http://www.nrc.gov/reading-rm/doc-collections... NUCLEAR REGULATORY COMMISSION [NRC-2010-0103] Withdrawal of Regulatory Guide 8.6 AGENCY: Nuclear Regulatory Commission. ACTION: Withdrawal of Regulatory Guide 8.6, ``Standard Test Procedure for Geiger-M...

40 CFR 180.8 - Withdrawal of petitions without prejudice.

Science.gov (United States)

2010-07-01

... prejudice. 180.8 Section 180.8 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... § 180.8 Withdrawal of petitions without prejudice. In some cases the Administrator will notify the... clarification or the obtaining of additional data. This withdrawal may be without prejudice to a future filing...

Quantitative Content Analysis of Communication Patterns on Facebook: A Case Study of the Croatian Government

Directory of Open Access Journals (Sweden)

Mato Brautović

2013-12-01

Full Text Available In the process of involving citizens more deeply in the democratic process, Facebook is becoming an increasingly important tool for governments in policy making. Facebook has the potential to increase political participation, but many governments fail to use it in the right way, because they just share information online and do not engage with their followers/citizens. This paper shows how the Croatian government is using Facebook and the communication patterns resulting from their work. The quantitative analysis of 20,546 posts and 52,311 comments show that communication is one way, rather than interactive. Government users do not follow the 90-9-1- rule of thumb for social networks.

Caffeine withdrawal symptoms and self-administration following caffeine deprivation.

Science.gov (United States)

Mitchell, S H; de Wit, H; Zacny, J P

1995-08-01

This study examined the effects of complete or partial caffeine deprivation on withdrawal symptomatology and self-administration of coffee in caffeine-dependent coffee drinkers. Nine habitual coffee drinkers abstained from dietary sources of caffeine for 33.5 h. Caffeine deprivation was manipulated by administering capsules containing 0%, 50%, or 100% of each subject's daily caffeine intake (complete, partial, and no deprivation conditions). Caffeine withdrawal symptomatology was measured using self-report questionnaires. Caffeine self-administration was measured using: i) the amount of coffee subjects earned on a series of concurrent random-ratio schedules that yielded coffee and money reinforcers; ii) the amount of earned coffee they consumed. Saliva samples revealed that subjects complied with the caffeine abstinence instructions. Caffeine withdrawal symptoms occurred reliably following complete caffeine deprivation, though not in the partial deprivation condition. Caffeine self-administration was not related to deprivation condition. We conclude that caffeine withdrawal symptomatology is not necessarily associated with increased caffeine consumption.

Steroid withdrawal in renal transplant patients: the Irish experience.

LENUS (Irish Health Repository)

Phelan, P J

2012-02-01

BACKGROUND: Steroid therapy is associated with significant morbidity in renal transplant recipients. However, there is concern that steroid withdrawal will adversely affect outcome. METHODS: We report on 241 renal transplant recipients on different doses of corticosteroids at 3 months (zero, <\\/= 5 mg\\/day, > 5 mg\\/day). Parameters analysed included blood pressure, lipid profile, weight change, new onset diabetes after transplantation (NODAT), allograft survival and acute rejection. RESULTS: Elimination of corticosteroids had no impact on allograft survival at 1 year. There were no cases of NODAT in the steroid withdrawal group compared with over 7% in each of the steroid groups. There were no significant improvements in weight gain, blood pressure control or total cholesterol with withdrawal of steroids before 3 months. CONCLUSIONS: In renal transplant patients treated with tacrolimus and mycophenolate, early withdrawal of steroids does not appear to adversely affect allograft outcome at 1 year. It may result in less NODAT.

Steroid withdrawal in renal transplant patients: the Irish experience.

LENUS (Irish Health Repository)

Phelan, P J

2010-10-29

BACKGROUND: Steroid therapy is associated with significant morbidity in renal transplant recipients. However, there is concern that steroid withdrawal will adversely affect outcome. METHODS: We report on 241 renal transplant recipients on different doses of corticosteroids at 3 months (zero, ≤5 mg\\/day, >5 mg\\/day). Parameters analysed included blood pressure, lipid profile, weight change, new onset diabetes after transplantation (NODAT), allograft survival and acute rejection. RESULTS: Elimination of corticosteroids had no impact on allograft survival at 1 year. There were no cases of NODAT in the steroid withdrawal group compared with over 7% in each of the steroid groups. There were no significant improvements in weight gain, blood pressure control or total cholesterol with withdrawal of steroids before 3 months. CONCLUSIONS: In renal transplant patients treated with tacrolimus and mycophenolate, early withdrawal of steroids does not appear to adversely affect allograft outcome at 1 year. It may result in less NODAT.

Determination of Screw and Nail Withdrawal Resistance of Some Important Wood Species

Directory of Open Access Journals (Sweden)

Alper Aytekin

2008-04-01

Full Text Available In this study, screw and nail withdrawal resistance of fir (Abies nordmanniana, oak (Quercus robur L. black pine (Pinus nigra Arnold and Stone pine (Pinus pinea L. wood were determined and compared. The data represent the testing of withdrawal resistance of three types of screws as smart, serrated and conventional and common nails. The specimens were prepared according to TS 6094 standards. The dimensions of the specimens were 5x5x15cm and for all of the directions. Moreover, the specimens were conditioned at ambient room temperature and 65±2% relative humidity. The screws and nails were installed according to ASTM-D 1761 standards. Nail dimensions were 2.5mm diameter and 50 mm length, conventional screws were 4x50mm, serrated screws were 4x45mm and smart screws were 4x50mm. Results show that the maximum screw withdrawal resistance value was found in Stone pine for the serrated screw. There were no significant differences between Stone pine and oak regarding screw withdrawal resistance values. Conventional screw yielded the maximum screw withdrawal resistance value in oak, followed by Stone pine, black pine and fir. Oak wood showed the maximum screw withdrawal resistance value for the smart screw, followed by Stone pine, black pine, and fir. Oak wood showed higher nail withdrawal resistances than softwood species. It was also determined that oak shows the maximum nail withdrawal resistance in all types. The nail withdrawal resistances at the longitudinal direction are lower with respect to radial and tangential directions.

A genetic perspective on the proposed inclusion of cannabis withdrawal in the DSM-5

Science.gov (United States)

Verweij, K.J.H.; Agrawal, A.; Nat, N.O.; Creemers, H.E.; Huizink, A.C.; Martin, N.G.; Lynskey, M.T.

2013-01-01

Background Various studies support the inclusion of cannabis withdrawal to the diagnosis of cannabis use disorders in the upcoming DSM-5. The aims of the current study were to (1) estimate the prevalence of DSM-5 cannabis withdrawal (Criterion B), (2) estimate the role of genetic and environmental influences on individual differences in cannabis withdrawal, and (3) determine the extent to which genetic and environmental influences on cannabis withdrawal overlap with those on DSM-IV defined abuse/dependence. Methods The sample included 2276 lifetime cannabis-using adult Australian twins. Cannabis withdrawal was defined in accordance with Criterion B of the proposed DSM-5 revisions. Cannabis abuse/dependence was defined as endorsing one or more DSM-IV criteria of abuse or three or more dependence criteria. The classical twin model was used to estimate the genetic and environmental influences on variation in cannabis withdrawal, as well as its covariation with abuse/dependence. Results Of all cannabis users 11.9% met criteria for cannabis withdrawal. Around 50% of between-individual variation in withdrawal could be attributed to additive genetic variation, and the rest of the variation was mostly due to non-shared environmental influences. Importantly, the genetic influences on cannabis withdrawal almost completely (99%) overlapped with those on abuse/dependence. Conclusions We showed that cannabis withdrawal symptoms exist among cannabis users, and that cannabis withdrawal is moderately heritable. Genetic influences on cannabis withdrawal are the same as those influencing abuse/dependence. These results add to the wealth of literature that recommends the addition of cannabis withdrawal to the diagnosis of DSM-5 cannabis use disorders. PMID:23194657

Enhancing On-Demand Multicast Routing Protocols using Mobility Prediction in Mobile Ad-hoc Network

Directory of Open Access Journals (Sweden)

Nermin Makhlouf

2014-08-01

Full Text Available A Mobile Ad hoc Network (MANET is a self-organizing wireless communication network in which mobile devices are based on no infrastructure like base stations or access points. Minimal configuration and quick deployment make ad hoc networks suitable for emergency situations like disaster recovery or military conflict. Since node mobility may cause links to be broken frequently, a very important issue for routing in MANETs is how to set reliable paths which can last as long as possible. To solve this problem, non-random behaviors for the mobility patterns that mobile users exhibit are exploited. This paper introduces a scheme to improve On-Demand Multicast Routing Protocol (ODMRP performances by using mobility prediction. 

Opioid withdrawal suppression efficacy of oral dronabinol in opioid dependent humans.

Science.gov (United States)

Lofwall, Michelle R; Babalonis, Shanna; Nuzzo, Paul A; Elayi, Samy Claude; Walsh, Sharon L

2016-07-01

The cannabinoid (CB) system is a rational novel target for treating opioid dependence, a significant public health problem around the world. This proof-of-concept study examined the potential efficacy of a CB1 receptor partial agonist, dronabinol, in relieving signs and symptoms of opioid withdrawal. Twelve opioid dependent adults participated in this 5-week, inpatient, double-blind, randomized, placebo-controlled study. Volunteers were maintained on double-blind oxycodone (30mg oral, four times/day) and participated in a training session followed by 7 experimental sessions, each testing a single oral test dose (placebo, oxycodone 30 and 60mg, dronabinol 5, 10, 20, and 30mg [decreased from 40mg]). Placebo was substituted for oxycodone maintenance doses for 21h before each session in order to produce measurable opioid withdrawal. Outcomes included observer- and participant-ratings of opioid agonist, opioid withdrawal and psychomotor/cognitive performance. Oxycodone produced prototypic opioid agonist effects (i.e. suppressing withdrawal and increasing subjective effects indicative of abuse liability). Dronabinol 5 and 10mg produced effects most similar to placebo, while the 20 and 30mg doses produced modest signals of withdrawal suppression that were accompanied by dose-related increases in high, sedation, bad effects, feelings of heart racing, and tachycardia. Dronabinol was not liked more than placebo, showed some impairment in cognitive performance, and was identified as marijuana with increasing dose. CB1 receptor activation is a reasonable strategy to pursue for the treatment of opioid withdrawal; however, dronabinol is not a likely candidate given its modest withdrawal suppression effects of limited duration and previously reported tachycardia during opioid withdrawal. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Experiential, Collaborative and Team Projects: Communication Audits in the MBA Communication Course

Science.gov (United States)

Hart, Claudia; Vroman, Margo; Stulz, Karin

2015-01-01

In this paper the authors discuss the challenges and rewards of building a graduate level Managerial Communication course around an experiential communication audit project. The purpose of the project was to provide MBA (Master of Business Administration) students with exposure to the real world responsibilities and demands of working in a complex…

Caffeine, sleep and wakefulness: implications of new understanding about withdrawal reversal.

Science.gov (United States)

James, Jack E; Keane, Michael A

2007-12-01

The broad aim of this review is to critically examine the implications of new understanding concerning caffeine withdrawal and withdrawal reversal in the context of research concerned with the effects of caffeine on sleep and wakefulness. A comprehensive search was conducted for relevant experimental studies in the PubMED and PsycINFO databases. Studies were assessed with particular reference to methodological adequacy for controlling against confounding due to caffeine withdrawal and withdrawal reversal. This assessment was used to clarify evidence of effects, highlight areas of ambiguity and derive recommendations for future research. It was found that researchers have generally failed to take account of the fact that habitual use of caffeine, even at moderate levels, leads to physical dependence evidenced by physiological, behavioural and subjective withdrawal effects during periods of abstinence. Consequently, there has been near-complete absence of adequate methodological controls against confounding due to reversal of withdrawal effects when caffeine is experimentally administered. The findings of what has been a substantial research effort to elucidate the effects of caffeine on sleep and wakefulness, undertaken over a period spanning decades, are ambiguous. Current shortcomings can be redressed by incorporating suitable controls in new experimental designs.

Children's judgements of social withdrawal behaviours.

Science.gov (United States)

Watling, Dawn

2015-06-01

Ding et al. (Brit. J. Dev. Psychol., 2015; 33, 159-173) demonstrated that Chinese children discriminate between the three subtypes of social withdrawal: Shyness, unsociability, and social avoidance. This commentary on the Ding et al.'s paper highlights the need to further explore the following: (1) children's understanding of the implications of being shy, unsociable, or socially avoidant, including assessing these which we know are associated with outcomes for socially withdrawn children; (2) what additional subtypes might exist naturally within the Chinese culture; and (3) consider the implications of social withdrawal on children's developing social skills. © 2015 The British Psychological Society.

The pattern and distribution of communicable diseases among ...

African Journals Online (AJOL)

Background: Global and regional estimates show that non-communicable diseases are rising in importance relative to other causes of ill health as populations age and the fight continues against communicable diseases. However, communicable diseases remain a major cause of mortality and morbidity in the developing ...

Home Network Technologies and Automating Demand Response

Energy Technology Data Exchange (ETDEWEB)

McParland, Charles

2009-12-01

Over the past several years, interest in large-scale control of peak energy demand and total consumption has increased. While motivated by a number of factors, this interest has primarily been spurred on the demand side by the increasing cost of energy and, on the supply side by the limited ability of utilities to build sufficient electricity generation capacity to meet unrestrained future demand. To address peak electricity use Demand Response (DR) systems are being proposed to motivate reductions in electricity use through the use of price incentives. DR systems are also be design to shift or curtail energy demand at critical times when the generation, transmission, and distribution systems (i.e. the 'grid') are threatened with instabilities. To be effectively deployed on a large-scale, these proposed DR systems need to be automated. Automation will require robust and efficient data communications infrastructures across geographically dispersed markets. The present availability of widespread Internet connectivity and inexpensive, reliable computing hardware combined with the growing confidence in the capabilities of distributed, application-level communications protocols suggests that now is the time for designing and deploying practical systems. Centralized computer systems that are capable of providing continuous signals to automate customers reduction of power demand, are known as Demand Response Automation Servers (DRAS). The deployment of prototype DRAS systems has already begun - with most initial deployments targeting large commercial and industrial (C & I) customers. An examination of the current overall energy consumption by economic sector shows that the C & I market is responsible for roughly half of all energy consumption in the US. On a per customer basis, large C & I customers clearly have the most to offer - and to gain - by participating in DR programs to reduce peak demand. And, by concentrating on a small number of relatively

Conducting a Withdrawal Survey.

Science.gov (United States)

Aldridge, Sue; Rowley, Jennifer

2001-01-01

A survey at Edge Hill College of Higher Education in Canada, designed to be part of the mechanism for monitoring and evaluating the quality of the student experience, revealed that key factors influencing withdrawal were: course not as expected, traveling difficulties, institution not as expected, domestic difficulties, and financial difficulties.…

Communications technology handbook

CERN Document Server

Lewis, Geoff

2013-01-01

This is the first point of reference for the communications industries. It offers an introduction to a wide range of topics and concepts encountered in the field of communications technology. Whether you are looking for a simple explanation, or need to go into a subject in more depth, the Communications Technology Handbook provides all the information you need in one single volume.This second edition has been updated to include the latest technology including: Video on DemandWire-less Distribution systemsHigh spee

Renewable energy: GIS-based mapping and modelling of potentials and demand

Science.gov (United States)

Blaschke, Thomas; Biberacher, Markus; Schardinger, Ingrid.; Gadocha, Sabine; Zocher, Daniela

2010-05-01

Worldwide demand of energy is growing and will continue to do so for the next decades to come. IEA has estimated that global primary energy demand will increase by 40 - 50% from 2003 to 2030 (IEA, 2005) depending on the fact whether currently contemplated energy policies directed towards energy-saving and fuel-diversification will be effectuated. The demand for Renewable Energy (RE) is undenied but clear figures and spatially disaggregated potentials for the various energy carriers are very rare. Renewable Energies are expected to reduce pressures on the environment and CO2 production. In several studies in Germany (North-Rhine Westphalia and Lower Saxony) and Austria we studied the current and future pattern of energy production and consumption. In this paper we summarize and benchmark different RE carriers, namely wind, biomass (forest and non-forest, geothermal, solar and hydro power. We demonstrate that GIS-based scalable and flexible information delivery sheds new light on the prevailing metaphor of GIS as a processing engine serving needs of users more on demand rather than through ‘maps on stock'. We compare our finding with those of several energy related EU-FP7 projects in Europe where we have been involved - namely GEOBENE, REACCESS, ENERGEO - and demonstrate that more and more spatial data will become available together with tools that allow experts to do their own analyses and to communicate their results in ways which policy makers and the public can readily understand and use as a basis for their own actions. Geoportals in combination with standardised geoprocessing today supports the older vision of an automated presentation of data on maps, and - if user privileges are given - facilities to interactively manipulate these maps. We conclude that the most critical factor in modelling energy supply and demand remain the economic valuation of goods and services, especially the forecast of future end consumer energy costs.

Time-dependent negative reinforcement of ethanol intake by alleviation of acute withdrawal.

Science.gov (United States)

Cunningham, Christopher L; Fidler, Tara L; Murphy, Kevin V; Mulgrew, Jennifer A; Smitasin, Phoebe J

2013-02-01

Drinking to alleviate the symptoms of acute withdrawal is included in diagnostic criteria for alcoholism, but the contribution of acute withdrawal relief to high alcohol intake has been difficult to model in animals. Ethanol dependence was induced by passive intragastric ethanol infusions in C57BL/6J (B6) and DBA/2J (D2) mice; nondependent control animals received water infusions. Mice were then allowed to self-administer ethanol or water intragastrically. The time course of acute withdrawal was similar to that produced by chronic ethanol vapor exposure in mice, reaching a peak at 7 to 9 hours and returning to baseline within 24 hours; withdrawal severity was greater in D2 than in B6 mice (experiment 1). Postwithdrawal delays in initial ethanol access (1, 3, or 5 days) reduced the enhancement in later ethanol intake normally seen in D2 (but not B6) mice allowed to self-infuse ethanol during acute withdrawal (experiment 2). The postwithdrawal enhancement of ethanol intake persisted over a 5-day abstinence period in D2 mice (experiment 3). D2 mice allowed to drink ethanol during acute withdrawal drank more ethanol and self-infused more ethanol than nondependent mice (experiment 4). Alcohol access during acute withdrawal increased later alcohol intake in a time-dependent manner, an effect that may be related to a genetic difference in sensitivity to acute withdrawal. This promising model of negative reinforcement encourages additional research on the mechanisms underlying acute withdrawal relief and its role in determining risk for alcoholism. Copyright © 2013 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.

Acute pregabalin withdrawal: a case report and review of the literature

Directory of Open Access Journals (Sweden)

Barrett JA

2015-05-01

Full Text Available Objective: Pregabalin is a commonly prescribed GABA analog most commonly used for the treatment of neuralgia. Recently, case reports on pregabalin have been published describing episodes that may be associated with withdrawal-like symptoms after extended or aggressive therapy. This report describes a case in which long term exposure of high dose pregabalin may have resulted in acute withdrawal, and outlines the subsequent medical management of these symptoms. Case Summary: A 61-year-old male presenting with severe agitation presumed to be withdrawal from long term and high dose exposure to pregabalin. Medical management included the use of haloperidol, diphenhydramine, lorazepam and the addition of clonidine over the course of several days for the pharmacological management of withdrawal symptoms. Discussion: Although case reports are available to guide clinicians in the recognition of acute pregabalin withdrawal, definitive evidence on how best to treat these patients remains severely limited. With an increase in the prescribing practices of pregabalin, insight into the acute management by fellow clinicians is further needed. Conclusion: Caution must be practiced when prescribing and educating patients on the use of pregabalin to prevent associated withdrawal-like symptoms. In addition, documentation by the medical community on methods utilized to treat pregabalin withdrawal syndromes remains crucial for the advancement of patient care. Benzodiazepines and clonidine are the current therapies that have been documented as potentially effective treatment modalities at this time.

Impacts of crop insurance on water withdrawals for irrigation

Science.gov (United States)

Deryugina, Tatyana; Konar, Megan

2017-12-01

Agricultural production remains particularly vulnerable to weather fluctuations and extreme events, such as droughts, floods, and heat waves. Crop insurance is a risk management tool developed to mitigate some of this weather risk and protect farmer income in times of poor production. However, crop insurance may have unintended consequences for water resources sustainability, as the vast majority of freshwater withdrawals go to agriculture. The causal impact of crop insurance on water use in agriculture remains poorly understood. Here, we determine the empirical relationship between crop insurance and irrigation water withdrawals in the United States. Importantly, we use an instrumental variables approach to establish causality. Our methodology exploits a major policy change in the crop insurance system - the 1994 Federal Crop Insurance Reform Act - which imposed crop insurance requirements on farmers. We find that a 1% increase in insured crop acreage leads to a 0.223% increase in irrigation withdrawals, with most coming from groundwater aquifers. We identify farmers growing more groundwater-fed cotton as an important mechanism contributing to increased withdrawals. A 1% increase in insured crop acreage leads to a 0.624% increase in cotton acreage, or 95,602 acres. These results demonstrate that crop insurance causally leads to more irrigation withdrawals. More broadly, this work underscores the importance of determining causality in the water-food nexus as we endeavor to achieve global food security and water resources sustainability.

Gut microbiota modulates alcohol withdrawal-induced anxiety in mice.

Science.gov (United States)

Xiao, Hui-Wen; Ge, Chang; Feng, Guo-Xing; Li, Yuan; Luo, Dan; Dong, Jia-Li; Li, Hang; Wang, Haichao; Cui, Ming; Fan, Sai-Jun

2018-05-01

Excessive alcohol consumption remains a major public health problem that affects millions of people worldwide. Accumulative experimental evidence has suggested an important involvement of gut microbiota in the modulation of host's immunological and neurological functions. However, it is previously unknown whether enteric microbiota is implicated in the formation of alcohol withdrawal-induced anxiety. Using a murine model of chronic alcoholism and withdrawal, we examined the impact of alcohol consumption on the possible alterations of gut microbiota as well as alcohol withdrawal-induced anxiety and behavior changes. The 16S rRNA sequencing revealed that alcohol consumption did not alter the abundance of bacteria, but markedly changed the composition of gut microbiota. Moreover, the transplantation of enteric microbes from alcohol-fed mice to normal healthy controls remarkably shaped the composition of gut bacteria, and elicited behavioral signs of alcohol withdrawal-induced anxiety. Using quantitative real-time polymerase chain reaction, we further confirmed that the expression of genes implicated in alcohol addiction, BDNF, CRHR1 and OPRM1, was also altered by transplantation of gut microbes from alcohol-exposed donors. Collectively, our findings suggested a possibility that the alterations of gut microbiota composition might contribute to the development of alcohol withdrawal-induced anxiety, and reveal potentially new etiologies for treating alcohol addiction. Copyright © 2018 The Author(s). Published by Elsevier B.V. All rights reserved.

Parent-child communication and psychological adjustment in children with a brain tumor.

Science.gov (United States)

Adduci, Annarita; Jankovic, Momcilo; Strazzer, Sandra; Massimino, Maura; Clerici, Carlo; Poggi, Geraldina

2012-08-01

Internalizing problems, anxiety, depression, withdrawal, and consequent social problems are frequently observed in children with brain tumors. The objective of this work is to describe the relationship between these psychological problems and the type of parent-child communication established about the disease. A group of 64 children surviving a brain tumor (aged 4-18 years) underwent psychological assessment by means of parent reports on the Child Behavior Checklist (CBCL) and the Vineland Adaptive Behavior Scales (VABS). A semi-structured interview with each child and their parents enabled us to classify the method of communication regarding the disease as "avoidance," "ineffective," and "effective." Demographic, clinical, and functional data relating to the disease were also collected. A significant relationship between the onset of Internalizing problems, withdrawal, anxiety-depression, and social problems and the presence of avoidance or ineffective communication about the disease was observed (P = 0.001, P = 0.001, P = 0.001, and P = 0.01, respectively). These psychological problems did not prove to be associated to demographic or clinical variables; however, they were found to be related to the children's residual functional problems. By contrast, the method of communication proved to be unrelated to clinical or functional variables, but it was associated to demographic variables such as sex and age at assessment. Effective (complete, truthful, consistent, comprehensible, gradual and continuous, and tailored) communication to the child about his/her condition proved to be associated with a better psychological outcome. Copyright © 2012 Wiley Periodicals, Inc.

I-centric Communications

CERN Document Server

Arbanowski, S; Steglich, S; Popescu-Zeletin, R

2001-01-01

During the last years, a variety of concepts for service integration and corresponding systems have gained momentum. On the one hand, they aim for the interworking and integration of classical telecommunications and data communications services. On the other hand, they are focusing on universal service access from a variety of end user systems. Looking at humans' communication behavior and communication space, it is obvious that human beings interact frequently in a set of contexts in their environment (communication space). Following this view, we want to build communication systems on the analysis of the individual communication spaces. The results are communication systems adapted to the specific demands of each individual. The authors introduce I-centric Communication Systems, an approach to design communication systems which adapt to the individual communication space and individual environment and situation. In this context "I" means I, or individual, "Centric" means adaptable to I requirements and a ce...

Pay for load demand - electricity pricing with load demand component

International Nuclear Information System (INIS)

Pyrko, Jurek; Sernhed, Kerstin; Abaravicius, Juozas

2003-01-01

This publication is part of a project called Direct and Indirect Load Control in Buildings. Peak load problems have attracted considerable attention in Sweden during last three winters, caused by a significant decrease in available reserve power, which is a consequence of political decisions and liberalisation of the electricity market. A possible way to lower peak loads, avoiding electricity shortages and reducing electricity costs both for users and utilities, is to make customers experience the price difference during peak load periods and, in this way, become more aware of their energy consumption pattern and load demand. As of January 1st 2001, one of the Swedish energy utilities - Sollentuna Energi - operating in the Stockholm area, introduced a new electricity tariff with differentiated grid fees based on a mean value of the peak load every month. This tariff was introduced for all residential customers in the service area. The objective of this study is to investigate the extent to which a Load Demand Component, included in electricity pricing, can influence energy use and load demand in residential buildings. What are the benefits and disadvantages for customers and utilities? This paper investigates the impact of the new tariff on the utility and different types of typical residential customers, making comparisons with previous tariff. Keywords Load demand, electricity pricing, tariff, residential customers, energy behaviour

Sclerosis: Implications for Interhemispheric Communication

Directory of Open Access Journals (Sweden)

A. Lunardelli

2014-01-01

Full Text Available We report a case of a 47-year-old woman with 35-year history of multiple sclerosis, who showed alien hand signs, a rare behavioural disorder that involves unilateral goal-directed movements that are contrary to the individual's intention. Alien hand syndrome has been described in multiple sclerosis (MS only occasionally and is generally suggestive of callosal disconnection. The patient presented also with bilateral limb apraxia and left hand agraphia, raising the possibility of cortical dysfunction or disconnection, in addition to corpus callosum and white matter involvement. Her specific pattern of symptoms supports the role of the corpus callosum in interhemispheric communication for complex as well as fine motor activities and may indicate that it can serve as both an inhibitory and excitatory function depending on task demands.

A rare case of complicated opioid withdrawal in delirium without convulsions

OpenAIRE

B Neeraj Raj; N Manamohan; Divya Hegde; Chandrashekar B Huded; Johnson Pradeep

2017-01-01

Opioids are one of the commonly abused substances in India. Opioid withdrawal symptoms classically include severe muscle cramps, bone aches, autonomic symptoms, anxiety, restlessness, insomnia, and temperature dysregulation. However, reports of cases with delirium during withdrawal are few. A 25-year-old male with severe opioid withdrawal symptoms developed delirium. Investigations were normal. There were no comorbidities, no significant past history and family history. Patient treated for op...

An alcohol withdrawal test battery measuring multiple behavioral symptoms in mice.

Science.gov (United States)

Metten, Pamela; Schlumbohm, Jason P; Huang, Lawrence C; Greenberg, Gian D; Hack, Wyatt R; Spence, Stephanie E; Crabbe, John C

2018-05-01

Despite acceptance that risk for alcohol-use disorder (AUD) has a large genetic component, the identification of genes underlying various components of risk for AUD has been hampered in humans, in part by the heterogeneity of expression of the phenotype. One aspect of AUD is physical dependence. Alcohol withdrawal is a serious consequence of alcohol dependence with multiple symptoms, many of which are seen in multiple species, and can be experienced over a wide-ranging time course. In the present three studies, we developed a battery of withdrawal tests in mice, examining behavioral symptoms from multiple domains that could be measured over time. To permit eventual use of the battery in different strains of mice, we used male and female mice of a genetically heterogeneous stock developed from intercrossing eight inbred strains. Withdrawal symptoms were assessed using commonly used tests after administration of ethanol in vapor for 72 continuous hours. We found significant effects of ethanol withdrawal versus air-breathing controls on nearly all symptoms, spanning 4 days following ethanol vapor inhalation. Withdrawal produced hypothermia, greater neurohyperexcitability (seizures and tremor), anxiety-like behaviors using an apparatus (such as reduced transitions between light and dark compartments), anhedonia (reduced sucrose preference), Straub tail, backward walking, and reductions in activity; however, there were no changes in thermal pain sensitivity, hyper-reactivity to handling, or anxiety-like emergence behaviors in other apparatus. Using these data, we constructed a refined battery of withdrawal tests. Individual differences in severity of withdrawal among different tests were weakly correlated at best. This battery should be useful for identifying genetic influences on particular withdrawal behaviors, which should reflect the influences of different constellations of genes. Published by Elsevier Inc.

Dependence and withdrawal reactions to benzodiazepines and sellective serotonin reuptake inhibitors: How did the health authorities react?

DEFF Research Database (Denmark)

Nielsen, Margrethe

2013-01-01

AIM: Our objective was to explore communications from drug agencies about benzodiazepine dependence and selective serotonin reuptake inhibitors (SSRIs) withdrawal reactions over time. METHODS: Documentary study. We searched the web-sites of the European Medicines Agency and the drug agencies in USA...... it is difficult for many patients to stop treatment. In the perspective of a precautionary principle, drug agencies have failed to acknowledge that SSRIs can cause dependence and have minimised the problem with regard to its frequency and severity. In the perspective of a risk management principle, the drug...

27 CFR 19.532 - Withdrawals of spirits for use in wine production.

Science.gov (United States)

2010-04-01

... use in wine production. 19.532 Section 19.532 Alcohol, Tobacco Products and Firearms ALCOHOL AND... Withdrawals Withdrawal of Spirits Without Payment of Tax § 19.532 Withdrawals of spirits for use in wine production. Wine spirits may be withdrawn to a bonded wine cellar without payment of tax for use in wine...

Evolution of Metabolic Abnormalities in Alcoholic Patients during Withdrawal

Directory of Open Access Journals (Sweden)

X. Vandemergel

2015-01-01

Full Text Available Chronic alcohol intoxication is accompanied by metabolic abnormalities. Evolution during the early withdrawal period has been poorly investigated. The aim of this study was to determine the evolution of metabolic parameters during alcohol withdrawal. Patients and Methods. Thirty-three patients admitted in our department for alcohol withdrawal were prospectively included. Results. Baseline hypophosphatemia was found in 24% of cases. FEPO4 was reduced from 14.2 ± 9% at baseline to 7.3 ± 4.2% at day 3 (Pnl, respectively. No correlation was found between the sodium and CPK levels (P=0.75 nor between the CPK level and the amount of alcohol ingested (rs = 0.084, P=0.097. Baseline urate level was elevated and returned to normal after three days. Baseline magnesium concentration was normal and stable over time. Conclusion. Chronic alcohol intoxication was accompanied by phosphaturia, rapidly reversible after alcohol withdrawal and inversely correlated with albuminemia, slight hyponatremia, low levels of 25 hydroxy vitamin D, elevated CPK level in about 30% of women, and hyperuricemia with rapid normalization.

It's self defense: how perceived discrimination promotes employee withdrawal.

Science.gov (United States)

Volpone, Sabrina D; Avery, Derek R

2013-10-01

Integrating theory on stress, stigma, and coping, the present study sheds light on how employees react to perceived discrimination (PD) in the workplace. Using three national samples, we found that PD based on race, sex, age, family obligation, and sexual orientation related to physical withdrawal (i.e., lateness, absenteeism,and intent to quit) indirectly through psychological withdrawal (i.e., burnout and engagement) such that PD corresponded in less engagement and more burnout, which related to increased lateness, absenteeism, and intent to quit [corrected].Further, these indirect relationships were moderated by employees' coping mechanisms with those who were more apt to change the situation or to avoid the stressor exhibiting weaker relationships between PD and psychological withdrawal. Though each of these studies is cross-sectional in nature and therefore cannot provide strong evidence of causal ordering of the variables in our model, the replication and extension of results over three databases and multiple forms of discrimination, coping, psychological, and physical withdrawal demonstrates that understanding the relationships explored in these studies can aid researchers and practitioners in enhancing employee quality of life and productivity.

Transcending communication barriers: A case for hybrid ...

African Journals Online (AJOL)

Therefore, communication can be improved by combining both feminine and masculine styles of communication, because male and female leaders can adapt to the demands of leadership in the transformational mode. Key words: secondary school; transformational leadership; channels of communication; cultural barriers ...

Variations in Withdrawal, Return Flow, and Consumptive Use of Water in Ohio and Indiana, with Selected Data from Wisconsin, 1999-2004

Science.gov (United States)

Shaffer, Kimberly H.

2009-01-01

This report contains an analysis of water withdrawal and return-flow data for Ohio and withdrawal data for Indiana and Wisconsin to compute consumptive-use coefficients and to describe monthly variability of withdrawals and consumptive use. Concurrent data were available for most water-use categories from 1999 through 2004. Average monthly water withdrawals are discussed for a variety of water-use categories, and average water use per month is depicted graphically for Ohio, Indiana, and Wisconsin (public supply only). For most water-use categories, the summer months were those of highest withdrawal and highest consumptive use. For public supply, average monthly withdrawals ranged from 1,380 million gallons per day (Mgal/d) (November) to 1,620 Mgal/d (July) in Ohio, 621 Mgal/d (December) to 816 Mgal/d (July) in Indiana, and 515 Mgal/d (December) to 694 Mgal/d (July) in Wisconsin. Ohio and Indiana thermoelectric facilities had large increases in average monthly withdrawals in the summer months (5,520 Mgal/d in March to 7,510 Mgal/d in August for Indiana; 7,380 Mgal/d in February to 10,040 Mgal/d in July for Ohio), possibly because of increased electricity production in the summer, a need for additional cooling-water withdrawals when intake-water temperature is high, or use of different types of cooling methods during different times of the year. Average industrial withdrawals ranged from 2,220 Mgal/d (December) to 2,620 Mgal/d (August) in Indiana and from 707 Mgal/d (January) to 787 Mgal/d (August) in Ohio. The Ohio and Indiana irrigation data showed that most withdrawals were in May through October for golf courses, nurseries, and crop irrigation. Commercial water withdrawals ranged from 30.4 Mgal/d (January) to 65.0 Mgal/d (September) in Indiana and from 23.2 Mgal/d (November) to 49.5 Mgal/d (August) in Ohio; commercial facilities that have high water demand in Ohio and Indiana are medical facilities, schools, amusement facilities, wildlife facilities, large stores

Neural communication patterns underlying conflict detection, resolution, and adaptation.

Science.gov (United States)

Oehrn, Carina R; Hanslmayr, Simon; Fell, Juergen; Deuker, Lorena; Kremers, Nico A; Do Lam, Anne T; Elger, Christian E; Axmacher, Nikolai

2014-07-30

In an ever-changing environment, selecting appropriate responses in conflicting situations is essential for biological survival and social success and requires cognitive control, which is mediated by dorsomedial prefrontal cortex (DMPFC) and dorsolateral prefrontal cortex (DLPFC). How these brain regions communicate during conflict processing (detection, resolution, and adaptation), however, is still unknown. The Stroop task provides a well-established paradigm to investigate the cognitive mechanisms mediating such response conflict. Here, we explore the oscillatory patterns within and between the DMPFC and DLPFC in human epilepsy patients with intracranial EEG electrodes during an auditory Stroop experiment. Data from the DLPFC were obtained from 12 patients. Thereof four patients had additional DMPFC electrodes available for interaction analyses. Our results show that an early θ (4-8 Hz) modulated enhancement of DLPFC γ-band (30-100 Hz) activity constituted a prerequisite for later successful conflict processing. Subsequent conflict detection was reflected in a DMPFC θ power increase that causally entrained DLPFC θ activity (DMPFC to DLPFC). Conflict resolution was thereafter completed by coupling of DLPFC γ power to DMPFC θ oscillations. Finally, conflict adaptation was related to increased postresponse DLPFC γ-band activity and to θ coupling in the reverse direction (DLPFC to DMPFC). These results draw a detailed picture on how two regions in the prefrontal cortex communicate to resolve cognitive conflicts. In conclusion, our data show that conflict detection, control, and adaptation are supported by a sequence of processes that use the interplay of θ and γ oscillations within and between DMPFC and DLPFC. Copyright © 2014 the authors 0270-6474/14/3410438-15$15.00/0.

8 CFR 246.4 - Immigration judge's authority; withdrawal and substitution.

Science.gov (United States)

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Immigration judge's authority; withdrawal... IMMIGRATION REGULATIONS RESCISSION OF ADJUSTMENT OF STATUS § 246.4 Immigration judge's authority; withdrawal and substitution. In any proceeding conducted under this part, the immigration judge shall have...

20 CFR 416.360 - Cancellation of a request to withdraw.

Science.gov (United States)

2010-04-01

....360 Section 416.360 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Filing of Applications Withdrawal of Application § 416.360... received after we have approved the withdrawal, the cancellation request is filed no later than 60 days...

Trajectories of Social Withdrawal from Middle Childhood to Early Adolescence

Science.gov (United States)

Oh, Wonjung; Rubin, Kenneth H.; Bowker, Julie C.; Booth-LaForce, Cathryn; Rose-Krasnor, Linda; Laursen, Brett

2008-01-01

Heterogeneity and individual differences in the developmental course of social withdrawal were examined longitudinally in a community sample (N = 392). General Growth Mixture Modeling (GGMM) was used to identify distinct pathways of social withdrawal, differentiate valid subgroup trajectories, and examine factors that predicted change in…

Temporal-pattern recognition by single neurons in a sensory pathway devoted to social communication behavior.

Science.gov (United States)

Carlson, Bruce A

2009-07-29

Sensory systems often encode stimulus information into the temporal pattern of action potential activity. However, little is known about how the information contained within these patterns is extracted by postsynaptic neurons. Similar to temporal coding by sensory neurons, social information in mormyrid fish is encoded into the temporal patterning of an electric organ discharge. In the current study, sensitivity to temporal patterns of electrosensory stimuli was found to arise within the midbrain posterior exterolateral nucleus (ELp). Whole-cell patch recordings from ELp neurons in vivo revealed three patterns of interpulse interval (IPI) tuning: low-pass neurons tuned to long intervals, high-pass neurons tuned to short intervals, and bandpass neurons tuned to intermediate intervals. Many neurons within each class also responded preferentially to either increasing or decreasing IPIs. Playback of electric signaling patterns recorded from freely behaving fish revealed that the IPI and direction tuning of ELp neurons resulted in selective responses to particular social communication displays characterized by distinct IPI patterns. The postsynaptic potential responses of many neurons indicated a combination of excitatory and inhibitory synaptic input, and the IPI tuning of ELp neurons was directly related to rate-dependent changes in the direction and amplitude of postsynaptic potentials. These results suggest that differences in the dynamics of short-term synaptic plasticity in excitatory and inhibitory pathways may tune central sensory neurons to particular temporal patterns of presynaptic activity. This may represent a general mechanism for the processing of behaviorally relevant stimulus information encoded into temporal patterns of activity by sensory neurons.

A Water-Withdrawal Input-Output Model of the Indian Economy.

Science.gov (United States)

Bogra, Shelly; Bakshi, Bhavik R; Mathur, Ritu

2016-02-02

Managing freshwater allocation for a highly populated and growing economy like India can benefit from knowledge about the effect of economic activities. This study transforms the 2003-2004 economic input-output (IO) table of India into a water withdrawal input-output model to quantify direct and indirect flows. This unique model is based on a comprehensive database compiled from diverse public sources, and estimates direct and indirect water withdrawal of all economic sectors. It distinguishes between green (rainfall), blue (surface and ground), and scarce groundwater. Results indicate that the total direct water withdrawal is nearly 3052 billion cubic meter (BCM) and 96% of this is used in agriculture sectors with the contribution of direct green water being about 1145 BCM, excluding forestry. Apart from 727 BCM direct blue water withdrawal for agricultural, other significant users include "Electricity" with 64 BCM, "Water supply" with 44 BCM and other industrial sectors with nearly 14 BCM. "Construction", "miscellaneous food products"; "Hotels and restaurants"; "Paper, paper products, and newsprint" are other significant indirect withdrawers. The net virtual water import is found to be insignificant compared to direct water used in agriculture nationally, while scarce ground water associated with crops is largely contributed by northern states.

Consequences of dextropropoxyphene market withdrawal in elderly patients with chronic pain.

Science.gov (United States)

Becquemont, Laurent; Delespierre, Tiba; Bauduceau, Bernard; Benattar-Zibi, Linda; Berrut, Gilles; Corruble, Emmanuelle; Danchin, Nicolas; Derumeaux, Geneviève; Doucet, Jean; Falissard, Bruno; Forette, Francoise; Hanon, Olivier; Pasquier, Florence; Pinget, Michel; Ourabah, Rissane; Bucher, Sophie; Lazkani, Aida; Piedvache, Celine; Bertin, Philippe

2014-10-01

Describe the consequences of dextropropoxyphene (DXP) market withdrawal on analgesic prescriptions and on the quality of therapeutic management of chronic pain. From a cohort of non-institutionalised elderly patients with chronic pain recruited by general practitioners, we selected patients who were treated with DXP daily for at least 6 months just prior to DXP market withdrawal and who had an evaluation of pain and its impact on daily activities before and after DXP withdrawal. One hundred three patients took DXP daily for chronic pain. Immediately after DXP market withdrawal, 42 (40.8%), 55 (53.4%) and 3 (2.9%) patients were treated with step 1, 2 and 3 analgesics, respectively, and 3 patients (2.9%) were no longer receiving any analgesic medication. Among the 55 patients who continued on step 2 analgesics, 37 were treated with tramadol, 14 with codeine and 9 with opium. Pain intensity and the impact of pain on daily activities remained stable. DXP market withdrawal had no consequences on the intensity or impact of chronic pain in elderly patients.

Flumazenil in treatment benzodiazepine withdrawal syndrome: Case report

Directory of Open Access Journals (Sweden)

Ramah Aleksandar J.

2015-01-01

Full Text Available Background: Today in the world and in Serbia is growing number of people who are addicted to benzodiazepine. A particular problem is the process of detoxification and treatment of benzodiazepine withdrawal syndrome due to a recurrence of symptoms of anxiety disorder, availability of benzodiazepines, falling motivation. Standard procedures have often proved unsuccessful and the last decade, and the search for new protocols, including the flumazenil, benzodiazepine receptor antagonist, is actualized. Case report: The patient aged 48 years was admitted to the specialist psychiatric clinic, for treatment of benzodiazepine addiction. Anxiety disorder was diagnosed since adolescence perennial addiction on benzodiazepines and the initial withdrawal syndrome. Former motivated topical treatments for detoxification were unsuccessful. The presence of dual diagnosis, persistence of both disorders in perennial cycle, treatment resistance and actual motivation contributed to the decision to opt rapid detoxification from benzodiazepines by flumazenil application protocol, for hospital treatment by adjuvant therapy with lamotrigine. After discharge from hospital in stable condition it was with no signs of withdrawal syndrome and a rebound of anxiety symptoms. Lamotrigine medication continued including CBT, held during the one-year abstinence monitoring, with sufficient social functionality. Discussion: The efficacy and safety of flumazenil in the treatment of benzodiazepine withdrawal syndrome was investigated in numerous clinical trials, and the mechanism of action is complex, from the benzodiazepine antagonist to inverse agonist in certain circumstances, as well as 'up-regulation' receptors, which together leads to a reduction in symptoms of abstinence syndrome and anxiety in the longer term after treatment, thereby acting favorably to the adherence and remission. Conclusions: Flumazenil protocol is an efficient method in the treatment of the benzodiazepine

WISDOM: A GIS-based supply demand mapping tool for woodfuel management

International Nuclear Information System (INIS)

Masera, Omar; Ghilardi, Adrian; Drigo, Rudi; Angel Trossero, Miguel

2006-01-01

In this paper, it is argued that adequately assessing the implications of the current patterns of woodfuel production and use, and the sustainable potentials of woodfuel resources, requires a holistic view and a better knowledge of the spatial patterns of woodfuel supply and demand. There is a need to conduct multi-scale spatially explicit analyses of woodfuel supply and demand that are able to articulate local heterogeneity at the regional and national levels. Studies that provide full-country coverage and are based on consistent integration of data at lower geographical scales are woefully lacking. This paper describes the Woodfuel Integrated Supply/Demand Overview Mapping model (WISDOM). This is a GIS-based tool, aimed at analyzing woodfuel demand and supply spatial patterns from a new perspective that includes: (a) the assembling of existing but dispersed information into single data sets, (b) a modular integration of these data sets, based on the analysis of key variables associated with woodfuel demand and supply patterns, and (c) a multiple-scale and spatially explicit representation of the results, in order to rank or highlight areas in which several criteria of interest coincide. The final objective of WISDOM is to assess the sustainability of woodfuel as a renewable and widespread energy source, while supporting strategic planning and policy formulation. Three case studies for Mexico, Slovenia, and Senegal illustrate the practical implementation and innovative results of using WISDOM. (author)

Estimation of the demand for public services communications. [market research and economic analysis for a communications satellite system

Science.gov (United States)

1976-01-01

Market analyses and economic studies are presented to support NASA planning for a communications satellite system to provide public services in health, education, mobile communications, data transfer, and teleconferencing.

Fast, Broad, and Frequent: Campus Crisis Communications Today Demand Social Media

Science.gov (United States)

Liggett, Billy

2012-01-01

The importance of communication during a school crisis has not changed in the 21st century. What has changed--and quite dramatically since 1999--is the way people communicate. Social media tools are now used in some form by 100 percent of all four-year universities in the United States as a way to reach students, according to a 2011 University of…

The energy demand in the Narino Department

International Nuclear Information System (INIS)

Unidad de Planeacion Minero Energetica, UPME

2000-01-01

In the object of making a first approach of regional energy requirements analysis and the good way of satisfying them, the UPME undertook a global energy study for the Narino Department. In this study (UPME 1999) was carried out an analysis of the energy demand and of the socioeconomic factors that determine it; they were also studied the consumptions and the current energy offer and the alternatives of future evolution, with the purpose of having the basic tools of a departmental energy plan. The present article refers specifically to the analysis of the demand and it seeks to show the readers the complexity and the volume of necessary information to carry out the demand studies. They are multiple factors that determine the energy demand in the Narino Department. The size, growth populations, geographical distribution and cultural characteristic, the border condition, the faulty infrastructure of communications, the agricultural economic structure and the low entrance per capita

Impact of realistic communications for fast-acting demand side management

DEFF Research Database (Denmark)

Dambrauskas, Paulius; Syed, Mazheruddin H.; Blair, Steven M.

2017-01-01

The rising penetration of intermittent energy resources is increasing the need for more diverse electrical energy resources that are able to support ancillary services. Demand side management (DSM) has a significant potential to fulfil this role, but several challenges are still impeding the wide...

Deadly pressure pneumothorax after withdrawal of misplaced feeding tube

DEFF Research Database (Denmark)

Andresen, Erik Nygaard; Frydland, Martin; Usinger, Lotte

2016-01-01

BACKGROUND: Many patients have a nasogastric feeding tube inserted during admission; however, misplacement is not uncommon. In this case report we present, to the best of our knowledge, the first documented fatality from pressure pneumothorax following nasogastric tube withdrawal. CASE PRESENTATION......, but our patient died less than an hour after withdrawal. The autopsy report stated that cause of death was tension pneumothorax, which developed following withdrawal of the misplaced feeding tube. CONCLUSIONS: The indications for insertion of nasogastric feeding tubes are many and the procedure...... is considered harmless; however, if the tube is misplaced there is good reason to be cautious on removal as this can unmask puncture of the pleura eliciting pneumothorax and, as this case report shows, result in an ultimately deadly tension pneumothorax....

DEMAND FOR MALAYSIA'S EXPORTS: EVIDENCE FROM THE ELECTRONICS INDUSTRY

OpenAIRE

Koi Nyen Wong

2006-01-01

This study estimates the determinants of foreign demand for Malaysia's top five electronics exports by SITC (Standard International Trade Classification) product groups from 1990 to 2001. Cointegration results indicate a unique long-run relationship between export demand for electronic products and relative prices and foreign income. Both the estimated long-run income and price elasticities of export demand are greater than 1, conforming to a pattern found in most fast-growing economies and i...

Estimated water withdrawals and return flows in Vermont in 2005 and 2020

Science.gov (United States)

Medalie, Laura; Horn, Marilee A.

2010-01-01

In 2005, about 12 percent of total water withdrawals (440 million gallons per day (Mgal/d)) in Vermont were from groundwater sources (51 Mgal/d), and about 88 percent were from surface-water sources (389 Mgal/d). Of total water withdrawals, about 78 percent were used for cooling at a power plant, 9 percent were withdrawn by public suppliers, about 5 percent were withdrawn for domestic use, about 3 percent were withdrawn for use at fish hatcheries, and the remaining 5 percent were divided among commercial/industrial, irrigation, livestock, and snowmaking uses. About 49 percent of the population of Vermont was supplied with drinking water by a public supplier, and 51 percent was self supplied. Some of the Minor Civil Divisions (MCDs) that had large self-supplied populations were located near the major cities of St. Albans, Burlington, Montpelier, Barre, and Rutland, where the cities themselves were served largely by public supply, but the surrounding areas were not. Most MCDs where withdrawals by community water systems totaled more than 1 Mgal/d used predominantly surface water, and those where withdrawals by community water systems totaled 1 Mgal/d or less used predominantly groundwater. Withdrawals of groundwater greater than 1 Mgal/d were made in Middlebury, Bethel, Hartford, Springfield, and Bennington, and withdrawals of surface water greater than 2 Mgal/d were made in Grand Isle, Burlington, South Burlington, Mendon, Brattleboro, and Vernon. Increases in groundwater withdrawals greater than 0.1 Mgal/d are projected for 2020 for Fairfax, Hardwick, Middlebury, Sharon, Proctor, Springfield, and Manchester. The largest projected increases in surface-water withdrawals from 2005 to 2020 are located along the center axis of the Green Mountains in the ski-area towns of Stowe, Warren, Mendon, Killington, and Wilmington. In 2005, withdrawals were at least 1 Mgal/d greater than return flows in South Burlington, Waterford, Orange, Mendon, Woodford, and Vernon. Many of

Caching Patterns and Implementation

Directory of Open Access Journals (Sweden)

Octavian Paul ROTARU

2006-01-01

Full Text Available Repetitious access to remote resources, usually data, constitutes a bottleneck for many software systems. Caching is a technique that can drastically improve the performance of any database application, by avoiding multiple read operations for the same data. This paper addresses the caching problems from a pattern perspective. Both Caching and caching strategies, like primed and on demand, are presented as patterns and a pattern-based flexible caching implementation is proposed.The Caching pattern provides method of expensive resources reacquisition circumvention. Primed Cache pattern is applied in situations in which the set of required resources, or at least a part of it, can be predicted, while Demand Cache pattern is applied whenever the resources set required cannot be predicted or is unfeasible to be buffered.The advantages and disadvantages of all the caching patterns presented are also discussed, and the lessons learned are applied in the implementation of the pattern-based flexible caching solution proposed.

Multi-Model Prediction for Demand Forecast in Water Distribution Networks

Directory of Open Access Journals (Sweden)

Rodrigo Lopez Farias

2018-03-01

Full Text Available This paper presents a multi-model predictor called Qualitative Multi-Model Predictor Plus (QMMP+ for demand forecast in water distribution networks. QMMP+ is based on the decomposition of the quantitative and qualitative information of the time-series. The quantitative component (i.e., the daily consumption prediction is forecasted and the pattern mode estimated using a Nearest Neighbor (NN classifier and a Calendar. The patterns are updated via a simple Moving Average scheme. The NN classifier and the Calendar are executed simultaneously every period and the most suited model for prediction is selected using a probabilistic approach. The proposed solution for water demand forecast is compared against Radial Basis Function Artificial Neural Networks (RBF-ANN, the statistical Autoregressive Integrated Moving Average (ARIMA, and Double Seasonal Holt-Winters (DSHW approaches, providing the best results when applied to real demand of the Barcelona Water Distribution Network. QMMP+ has demonstrated that the special modelling treatment of water consumption patterns improves the forecasting accuracy.

Potential harms, anonymization, and the right to withdraw consent to biobank research.

Science.gov (United States)

Eriksson, Stefan; Helgesson, Gert

2005-09-01

This paper discusses the potential harms involved in biobank research and how ethical review, informed consent, withdrawals, and anonymization of samples should be handled in the light of these harms. There is less risk involved in biobank research than in human subject research; it should therefore be treated differently. In our view, anonymization should not be an automatically permissible response to requests for withdrawal. Nor should a request for withdrawal necessarily stop research on identifiable samples. Apart from not being particularly appropriate for protecting the interests of individuals, anonymization of samples has a negative impact on research. We suggest that the current view on withdrawal from research, supported by the Declaration of Helsinki and subsequent ethical guidelines, be abandoned in the context of biobank research and be replaced by an approach inspired by the Nuremberg Code. This approach requires those wishing to withdraw their samples from research to present sufficient reason for doing so. Our interpretation of 'sufficient reason' includes all those involving genuine, deeply felt concerns that are not based on misconceptions. Still, this underlines the fact that we all share a responsibility for health research and that no one should take withdrawal from biobank research lightly.

A 'symptom-triggered' approach to alcohol withdrawal management.

Science.gov (United States)

Murdoch, Jay; Marsden, Janet

In acute hospital settings, alcohol withdrawal often causes significant management problems and complicates a wide variety of concurrent conditions, placing a huge burden on the NHS. A significant number of critical incidents around patients who were undergoing detoxification in a general hospital setting led to the need for a project to implement and evaluate an evidence-based approach to the management of alcohol detoxification-a project that included a pre-intervention case note audit, the implementation of an evidence-based symptom-triggered detoxification protocol, and a post-intervention case note audit. This change in practice resulted in an average reduction of almost 60% in length of hospital stay and a 66% reduction in the amount of chlordiazepoxide used in detoxification, as well as highlighting that 10% of the sample group did not display any signs of withdrawal and did not require any medication. Even with these reductions, no patient post-intervention developed any severe signs of withdrawal phenomena, such as seizures or delirium tremens. The savings to the trust (The Pennine Acute Hospital Trust) are obvious,but the development of a consistent, quality service will lead to fewer long-term negative effects for patients that can be caused by detoxification. This work is a project evaluation of a locally implemented strategy, which, it was hypothesised,would improve care by providing an individualised treatment plan for the management of alcohol withdrawal symptoms.

Obesity and the Social Withdrawal Syndrome.

Science.gov (United States)

Rotenberg, Ken J; Bharathi, Carla; Davies, Helen; Finch, Tom

2017-08-01

The relation between obesity and Social Withdrawal Syndrome (SWS) was examined using the data gathered by Rotenberg, Bharathi, Davies, and Finch (2013). One hundred and 35 undergraduates (80 females; Mage=21years-10months) completed standardized scales that assessed the SWS (low emotional trust beliefs in close others, low disclosure to close others, and high loneliness). BMI was calculated from self-reported weight and height. As hypothesized, quadratic relations were found in which participants with BMI>30 (i.e., obese) demonstrated the SWS pattern of low emotional trust beliefs in close others, low disclosure to close others, and high loneliness. As further evidence, lower emotional trust in close others, lower disclosure to close others, and greater loneliness were found for obese participants (>30 BMI, n=27) than both normal weight (<25 BMI, n=67) and overweight participants (25 to 30 BMI, n=41). The findings confirmed the hypothesis that obesity was associated with the SWS. The findings suggested that the lack of trust in others by obese individuals contributes to their unwillingness to seek out help for health and psychosocial problems. Copyright © 2017 Elsevier Ltd. All rights reserved.

A Case Report of Severe Delirium after Amantadine Withdrawal

Directory of Open Access Journals (Sweden)

Franz Marxreiter

2017-03-01

Full Text Available Amantadine is frequently used in addition to dopaminergic substances like dopamine agonists or L-Dopa in advanced Parkinson disease (PD. However, adverse effects like hallucinations limit its use. PD patients developing severe psychotic symptoms upon treatment with either dopaminergic substances and/or amantadine need to stop intake of any psychotropic substance. Here, we report the case of a 71-year-old PD patient without previously known cognitive impairment. He presented with drug-induced psychotic symptoms due to changes in his therapeutic regimen (increase in COMT inhibitors, newly introduced MAO B inhibitors. Also, amantadine had been part of his long-term medication for more than 2 years. The severity of his psychotic symptoms required a L-Dopa monotherapy. After changing his medication, the patient developed severe delirium that resolved rapidly after i.v. amantadine infusion, suggesting an amantadine withdrawal syndrome. Amantadine withdrawal syndrome is a rare adverse event that may present even in PD patients without cognitive impairment. This case report highlights the need for a gradual withdrawal of amantadine even if acute and severe psychotic symptoms are present. Moreover, this is the first report of a cognitively unimpaired patient developing an amantadine withdrawal syndrome.

20 CFR 404.641 - Cancellation of a request to withdraw.

Science.gov (United States)

2010-04-01

....641 Section 404.641 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Filing of Applications and Other Forms Withdrawal of Application § 404.641... received after we have approved the withdrawal, the request is filed no later than 60 days after the date...

Blocking of beta-2 adrenergic receptors hastens recovery from hypoglycemia-associated social withdrawal.

Science.gov (United States)

Park, Min Jung; Guest, Christopher B; Barnes, Meredith B; Martin, Jonathan; Ahmad, Uzma; York, Jason M; Freund, Gregory G

2008-11-01

Hypoglycemia is associated with a variety of adverse behaviors including fatigue, confusion and social withdrawal. While these clinical symptoms are well characterized, the mechanism of their cause is not understood. Here we investigated how insulin-induced hypoglycemia causes social withdrawal. Male 8-12-week-old C57BL/6J mice were injected intraperitoneally (IP) with or without and/or insulin, norepinephrine (NE) and epinephrine (Epi), terbutaline and butoxamine with subsequent measurement of blood glucose, social withdrawal and plasma catecholamines. Insulin generated (0.75h post-injection) significant hypoglycemia with blood glucose nadirs of 64+/-4 and 48+/-5mg/dl for 0.8 and 1.2units/kg of insulin, respectively. Insulin (0.8 or 1.2units/kg) caused near total social withdrawal at 0.75h with full recovery not occurring until 4h (0.8units/kg) or 8h (1.2units/kg) post-insulin injection. Insulin also caused a marked elevation in plasma catecholamines. Basal 12h fasting NE and Epi were 287+/-38 and 350+/-47pg/ml, respectively. Insulin at 0.8units/kg increased plasma NE and Epi to 994+/-73 and 1842+/-473pg/ml, respectively. Administration of exogenous NE or Epi caused social withdrawal similar in magnitude to insulin. Importantly, administration of the beta-2 adrenergic receptor agonist terbutaline also caused social withdrawal while administration of the beta-2 adrenergic receptor antagonist butoxamine blocked NE-induced social withdrawal. Finally, butoxamine blocked insulin-induced social withdrawal. These data demonstrate that hypoglycemia-associated social withdrawal is dependent on catecholamines via a beta-2 receptor-mediated pathway.

Window-Based Popularity Caching for IPTV On-Demand Services

OpenAIRE

Hsuan Chiu; Chi-He Chang; Chao-Wei Tseng; Chi-Shi Liu

2011-01-01

In recent years, many telecommunication companies have regarded IP network as a new delivery platform for providing TV services because IP network is equipped with two-way and high-speed communication abilities which are appropriate to provide on-demand services and linear TV programs. However, in this IPTV system, the requests of VOD (video on demand) are usually aggregated in a short period intensively and user preferences are fluctuated dynamically. Moreover, the VOD content is updated fre...

Safety of oral dronabinol during opioid withdrawal in humans.

Science.gov (United States)

Jicha, Crystal J; Lofwall, Michelle R; Nuzzo, Paul A; Babalonis, Shanna; Elayi, Samy Claude; Walsh, Sharon L

2015-12-01

Opioid dependence remains a significant public health problem worldwide with only three FDA-approved treatments, all targeting the mu-opioid receptor. Dronabinol, a cannabinoid (CB) 1 receptor agonist, is currently under investigation as a novel opioid withdrawal treatment. This study reports on safety outcomes of dronabinol among adults in opioid withdrawal. Twelve adults physically dependent on short-acting opioids participated in this 5-week within-subject, randomized, double blind, placebo-controlled inpatient study. Volunteers were maintained on oral oxycodone 30 mg qid. Double-blind placebo substitutions occurred for 21 h before each of 7 experimental sessions in order to produce opioid withdrawal. A single oral test dose was administered each session (placebo, oxycodone 30 and 60 mg, dronabinol 5, 10, 20, and 30 mg [decreased from 40 mg]). Heart rate, blood pressure, respiratory outcomes and pupil diameter were assessed repeatedly. Dronabinol 40 mg produced sustained sinus tachycardia accompanied by anxiety and panic necessitating dose reduction to 30 mg. Sinus tachycardia and anxiety also occurred in one volunteer after dronabinol 20mg. Compared to placebo, dronabinol 20 and 30 mg produced significant increases in heart rate beginning 1h after drug administration that lasted approximately 2h (popioid agonist effects (e.g., miosis). Dronabinol 20mg and higher increased heart rate among healthy adults at rest who were in a state of opioid withdrawal, raising concern about its safety. These results have important implications for future dosing strategies and may limit the utility of dronabinol as a treatment for opioid withdrawal. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Method for Estimating Water Withdrawals for Livestock in the United States, 2005

Science.gov (United States)

Lovelace, John K.

2009-01-01

Livestock water use includes ground water and surface water associated with livestock watering, feedlots, dairy operations, and other on-farm needs. The water may be used for drinking, cooling, sanitation, waste disposal, and other needs related to the animals. Estimates of water withdrawals for livestock are needed for water planning and management. This report documents a method used to estimate withdrawals of fresh ground water and surface water for livestock in 2005 for each county and county equivalent in the United States, Puerto Rico, and the U.S. Virgin Islands. Categories of livestock included dairy cattle, beef and other cattle, hogs and pigs, laying hens, broilers and other chickens, turkeys, sheep and lambs, all goats, and horses (including ponies, mules, burros, and donkeys). Use of the method described in this report could result in more consistent water-withdrawal estimates for livestock that can be used by water managers and planners to determine water needs and trends across the United States. Water withdrawals for livestock in 2005 were estimated by using water-use coefficients, in gallons per head per day for each animal type, and livestock-population data. Coefficients for various livestock for most States were obtained from U.S. Geological Survey water-use program personnel or U.S. Geological Survey water-use publications. When no coefficient was available for an animal type in a State, the median value of reported coefficients for that animal was used. Livestock-population data were provided by the National Agricultural Statistics Service. County estimates were further divided into ground-water and surface-water withdrawals for each county and county equivalent. County totals from 2005 were compared to county totals from 1995 and 2000. Large deviations from 1995 or 2000 livestock withdrawal estimates were investigated and generally were due to comparison with reported withdrawals, differences in estimation techniques, differences in livestock

Linguistic Communication: A Comparative Field Study. Esperanto Document 46A.

Science.gov (United States)

Piron, Claude

This paper explores the various options available for dealing with the demands and costs of communication in a world of many languages. Globalization has increased the demand for language services necessary to accomplish effective communication. It is argued that the day is not far off when the complications, costs, and inequalities of language…

21 CFR 314.530 - Withdrawal procedures.

Science.gov (United States)

2010-04-01

... Serious or Life-Threatening Illnesses § 314.530 Withdrawal procedures. (a) For new drugs approved under... benefit; (2) The applicant fails to perform the required postmarketing study with due diligence; (3) Use...

Emplotting Hikikomori: Japanese Parents' Narratives of Social Withdrawal.

Science.gov (United States)

Rubinstein, Ellen

2016-12-01

Hikikomori, often glossed as "social withdrawal," emerged as a sociomedical condition among Japanese youth at the end of the twentieth century, and it continues to fascinate and concern the public. Explanatory frameworks for hikikomori abound, with different stakeholders attributing it to individual psychopathology, poor parenting, and/or a lack of social support structures. This article takes an interpretive approach to hikikomori by exploring parents' narrative constructions of hikikomori children in support group meetings and in-depth interviews. I argue that some parents were able to find hope in hikikomori by 'emplotting' their children's experiences into a larger narrative about onset, withdrawal, and recovery, which helped them remain invested in the present by maintaining a sense of possibility about the future. Contrary to literature that examines hikikomori as an epidemic of isolated individuals, I demonstrate how parents play a key role in hikikomori through meaning-making activities that have the potential to shape their children's experiences of withdrawal.

Control device for the withdrawal of control rod

International Nuclear Information System (INIS)

Ando, Masaki.

1985-01-01

Purpose: To significantly suppress the maximum value of the control-rod worth upon control rod withdrawal. Constitution: At first, a signal for designating the first class is sent from a class-control section to the group-control section. In the group-control section, the peripheral group among the first class is designated by which the withdrawal of the control rods other than the peripheral group is inhibited and the control-rods in the peripheral group are withdrawn one by one. When all of them have been withdrawn, the group-control section designates the central group of the first class. All the control rods of the central group have been withdrawn, then the group-control section designates the peripheral group of the second class. Thereafter, the central group in the second class is designated. The control rods are thus withdrawn in the same manner hereinafter. The maximum value for the control-rod worth can be decreased by such a withdrawing sequence for the control rods. (Horiuchi, T.)

40 CFR 96.86 - Withdrawal from NOX Budget Trading Program.