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Sample records for delivery condition codes

  1. Under-coding of secondary conditions in coded hospital health data: Impact of co-existing conditions, death status and number of codes in a record.

    Science.gov (United States)

    Peng, Mingkai; Southern, Danielle A; Williamson, Tyler; Quan, Hude

    2017-12-01

    This study examined the coding validity of hypertension, diabetes, obesity and depression related to the presence of their co-existing conditions, death status and the number of diagnosis codes in hospital discharge abstract database. We randomly selected 4007 discharge abstract database records from four teaching hospitals in Alberta, Canada and reviewed their charts to extract 31 conditions listed in Charlson and Elixhauser comorbidity indices. Conditions associated with the four study conditions were identified through multivariable logistic regression. Coding validity (i.e. sensitivity, positive predictive value) of the four conditions was related to the presence of their associated conditions. Sensitivity increased with increasing number of diagnosis code. Impact of death on coding validity is minimal. Coding validity of conditions is closely related to its clinical importance and complexity of patients' case mix. We recommend mandatory coding of certain secondary diagnosis to meet the need of health research based on administrative health data.

  2. Applying a rateless code in content delivery networks

    Science.gov (United States)

    Suherman; Zarlis, Muhammad; Parulian Sitorus, Sahat; Al-Akaidi, Marwan

    2017-09-01

    Content delivery network (CDN) allows internet providers to locate their services, to map their coverage into networks without necessarily to own them. CDN is part of the current internet infrastructures, supporting multi server applications especially social media. Various works have been proposed to improve CDN performances. Since accesses on social media servers tend to be short but frequent, providing redundant to the transmitted packets to ensure lost packets not degrade the information integrity may improve service performances. This paper examines the implementation of rateless code in the CDN infrastructure. The NS-2 evaluations show that rateless code is able to reduce packet loss up to 50%.

  3. Random Linear Network Coding for 5G Mobile Video Delivery

    Directory of Open Access Journals (Sweden)

    Dejan Vukobratovic

    2018-03-01

    Full Text Available An exponential increase in mobile video delivery will continue with the demand for higher resolution, multi-view and large-scale multicast video services. Novel fifth generation (5G 3GPP New Radio (NR standard will bring a number of new opportunities for optimizing video delivery across both 5G core and radio access networks. One of the promising approaches for video quality adaptation, throughput enhancement and erasure protection is the use of packet-level random linear network coding (RLNC. In this review paper, we discuss the integration of RLNC into the 5G NR standard, building upon the ideas and opportunities identified in 4G LTE. We explicitly identify and discuss in detail novel 5G NR features that provide support for RLNC-based video delivery in 5G, thus pointing out to the promising avenues for future research.

  4. Rethinking mobile delivery: using Quick Response codes to access information at the point of need.

    Science.gov (United States)

    Lombardo, Nancy T; Morrow, Anne; Le Ber, Jeanne

    2012-01-01

    This article covers the use of Quick Response (QR) codes to provide instant mobile access to information, digital collections, educational offerings, library website, subject guides, text messages, videos, and library personnel. The array of uses and the value of using QR codes to push customized information to patrons are explained. A case is developed for using QR codes for mobile delivery of customized information to patrons. Applications in use at the Libraries of the University of Utah will be reviewed to provide readers with ideas for use in their library. Copyright © Taylor & Francis Group, LLC

  5. Coding update of the SMFM definition of low risk for cesarean delivery from ICD-9-CM to ICD-10-CM.

    Science.gov (United States)

    Armstrong, Joanne; McDermott, Patricia; Saade, George R; Srinivas, Sindhu K

    2017-07-01

    In 2015, the Society for Maternal-Fetal Medicine developed a low risk for cesarean delivery definition based on administrative claims-based diagnosis codes described by the International Classification of Diseases, Ninth Revision, Clinical Modification. The Society for Maternal-Fetal Medicine definition is a clinical enrichment of 2 available measures from the Joint Commission and the Agency for Healthcare Research and Quality measures. The Society for Maternal-Fetal Medicine measure excludes diagnosis codes that represent clinically relevant risk factors that are absolute or relative contraindications to vaginal birth while retaining diagnosis codes such as labor disorders that are discretionary risk factors for cesarean delivery. The introduction of the International Statistical Classification of Diseases, 10th Revision, Clinical Modification in October 2015 expanded the number of available diagnosis codes and enabled a greater depth and breadth of clinical description. These coding improvements further enhance the clinical validity of the Society for Maternal-Fetal Medicine definition and its potential utility in tracking progress toward the goal of safely lowering the US cesarean delivery rate. This report updates the Society for Maternal-Fetal Medicine definition of low risk for cesarean delivery using International Statistical Classification of Diseases, 10th Revision, Clinical Modification coding. Copyright © 2017. Published by Elsevier Inc.

  6. Appraisal of the Effectiveness of CODE; The Coordinated Delivery System for the South Central Research Library Council, January to December 1970.

    Science.gov (United States)

    Faibisoff, Sylvia G.

    A major concern of the South Central Research Library Council in establishing an interlibrary loan network was the development of a Coordinated Delivery system (CODE). Several means of delivery were considered--the U.S. mails, commercial trucking (Greyhound, United Parcel Service), and use of the public library system's delivery services. A…

  7. Mode of delivery has an independent impact on neonatal condition at birth.

    Science.gov (United States)

    Prior, Tomas; Kumar, Sailesh

    2014-10-01

    Current intra-partum monitoring techniques are often criticized for their poor specificity, with their performance frequently evaluated using measures of the neonatal condition at birth as a surrogate marker for intra-partum fetal compromise. However, these measures may potentially be influenced by a multitude of other factors, including the mode of delivery itself. This study aimed to investigate the impact of mode of delivery on neonatal condition at birth. This prospective observational study, undertaken at a tertiary referral maternity unit in London, UK, included 604 'low risk' women recruited prior to delivery. Commonly assessed neonatal outcome variables (Apgar score at 1 and 5min, umbilical artery pH and base excess, neonatal unit admission, and a composite neonatal outcome score) were used to compare the condition at birth between babies born by different modes of delivery, using one-way ANOVA and chi-squared testing. Infants born by instrumental delivery for presumed fetal compromise had the poorest condition at birth (mean composite score=1.20), whereas those born by Cesarean section for presumed fetal compromise had a better condition at birth (mean composite score=0.64) (p=surrogate marker of intra-partum fetal compromise. When evaluating the efficacy of intra-partum monitoring techniques, the isolated use of Apgar scores, umbilical artery acidosis and neonatal unit admission should be discouraged. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  8. Coding and transmission of subband coded images on the Internet

    Science.gov (United States)

    Wah, Benjamin W.; Su, Xiao

    2001-09-01

    Subband-coded images can be transmitted in the Internet using either the TCP or the UDP protocol. Delivery by TCP gives superior decoding quality but with very long delays when the network is unreliable, whereas delivery by UDP has negligible delays but with degraded quality when packets are lost. Although images are delivered currently over the Internet by TCP, we study in this paper the use of UDP to deliver multi-description reconstruction-based subband-coded images. First, in order to facilitate recovery from UDP packet losses, we propose a joint sender-receiver approach for designing optimized reconstruction-based subband transform (ORB-ST) in multi-description coding (MDC). Second, we carefully evaluate the delay-quality trade-offs between the TCP delivery of SDC images and the UDP and combined TCP/UDP delivery of MDC images. Experimental results show that our proposed ORB-ST performs well in real Internet tests, and UDP and combined TCP/UDP delivery of MDC images provide a range of attractive alternatives to TCP delivery.

  9. ECC delivery to lower plenum under downcomer injection part 2. RELAP5 assessment

    International Nuclear Information System (INIS)

    Bang, Young Seok; Shin, An Dong; Kim, Hho Jung

    2000-01-01

    In the present study, the capability of the thermal-hydraulic codes, RELAP5/MOD3.2.2 gamma, in predicting the steam-water interaction and the related ECC delivery to lower plenum under downcomer injection condition during refill phase is evaluated using the experimental data of the UPTF Test 21A. The facility is modeled in detail, and the test condition simulated for code calculations. The calculation result is compared with the applicable measurement data and discussed for the pressure response, ECC bypass behavior, lower plenum delivery, global water mass distribution, and local behavior in downcomer

  10. Color-coded duplex sonography in the study of thyroid pathologic conditions

    International Nuclear Information System (INIS)

    Anguissola, R.; Bozzini, A.; Campani, R.; Bottinelli, O.; Genovese, E.; Guglielmoni, B.; Fulle, I.; Bandi, G.

    1991-01-01

    The authors examined 110 patients with suspected pathologic conditions of the thyroid by means of color-coded duplex US. In addition to the information yielded by conventional US, this technique allows organ vascularization to be demonstrated. Five normal patients were considered as a control group: no tissue vascularization was demonstrated in these cases. In 8 patients presenting with carcinoma or recurrences, vascularization was markedly increased both peripheral and central to the nodule. A few doubts are still to be solved as to the diagnostic value of color-coded duplex US in the evaluation of non-carcinomas nodular pathologic conditions. As a matter of fact, non-functioning avascular adenomas can be demonstrated only in a very low percentage of cases (66%). Color-coded duplex US proved extremely sensitive and specific in depicting malignant neoplasms. Moreover, the use of fine.needle biopsy could be optimized and subsequently reduced. Color-coded duplex US proved to be markedly superior to othe rmethods and techniques in the study of thyroid diseases, especially thyroiditis and multiple pathologic conditions. The simultaneous presence of hypocapture at scintigraphy and peripheral and central vascularization in a single nodule or within multinodular struma at color-Doppler was highly suggestive of malignant thyroid neoplasm. Color-coded duplex US is a low-cost technique, which can be performed on an outpatient basis. Moreover, it is not invasive, nor does it damage the thyroid. That is why its use is almost mandatory in the study of pathologic conditions of the thyroid

  11. Periodic Boundary Conditions in the ALEGRA Finite Element Code

    International Nuclear Information System (INIS)

    Aidun, John B.; Robinson, Allen C.; Weatherby, Joe R.

    1999-01-01

    This document describes the implementation of periodic boundary conditions in the ALEGRA finite element code. ALEGRA is an arbitrary Lagrangian-Eulerian multi-physics code with both explicit and implicit numerical algorithms. The periodic boundary implementation requires a consistent set of boundary input sets which are used to describe virtual periodic regions. The implementation is noninvasive to the majority of the ALEGRA coding and is based on the distributed memory parallel framework in ALEGRA. The technique involves extending the ghost element concept for interprocessor boundary communications in ALEGRA to additionally support on- and off-processor periodic boundary communications. The user interface, algorithmic details and sample computations are given

  12. IMPORTANCE OF DELIVERY CONDITIONS IN THE EXTERNAL PRICE CALCULATION

    Directory of Open Access Journals (Sweden)

    Violeta ISAI

    2005-01-01

    Full Text Available The delivery conditions of the merchandise at export, established by the rules INCOTERMS2000, influence the external price structure. There are some conditions in which the external priceincludes only the value of the merchandise and other conditions in which, besides the value of themerchandise, the price includes also the external transport and insurance. In the case of the exportson commercial credit, when it appears the notion of external interest, this one may be included in theprice or may be invoiced separately, thus defining gross external prices and net external prices.

  13. Disparities in Chronic Conditions Among Women Hospitalized for Delivery in the United States, 2005-2014.

    Science.gov (United States)

    Admon, Lindsay K; Winkelman, Tyler N A; Moniz, Michelle H; Davis, Matthew M; Heisler, Michele; Dalton, Vanessa K

    2017-12-01

    To estimate trends in the prevalence and socioeconomic distribution of chronic conditions among women hospitalized for obstetric delivery in the United States. A retrospective, serial cross-sectional analysis was conducted using 2005-2014 data from the National Inpatient Sample. We estimated the prevalence of eight common, chronic conditions, each associated with obstetric morbidity and mortality, among all childbearing women and then across socioeconomic predictors of obstetric outcomes. Differences over time were measured and compared across rural and urban residence, income, and payer subgroups for each condition. We identified 8,193,707 delivery hospitalizations, representing 39,273,417 delivery hospitalizations occurring nationally between 2005 and 2014. Identification of at least one chronic condition increased significantly between 2005-2006 and 2013-2014 (66.9 per 1,000 delivery hospitalizations in 2005-2006 compared with 91.8 per 1,000 delivery hospitalizations in 2013-2014). The prevalence of multiple chronic conditions also increased during the study period, from 4.7 (95% CI 4.2-5.2) to 8.1 (95% CI 7.8-8.4) per 1,000 delivery hospitalizations between 2005-2006 and 2013-2014. Chronic respiratory disease, chronic hypertension, substance use disorders, and pre-existing diabetes were the disorders with the greatest increases in prevalence over time. Increasing disparities over time were identified across all socioeconomic subgroups analyzed including rural compared with urban residence, income, and payer. Key areas of concern include the rate at which substance use disorders rose among rural women and the disproportionate burden of each condition among women from the lowest income communities and among women with Medicaid as their primary payer. Between 2005-2006 and 2013-2014, the prevalence of chronic conditions increased across all segments of the childbearing population. Widening disparities were identified over time with key areas of concern including

  14. The analytical solution for drug delivery system with nonhomogeneous moving boundary condition

    Science.gov (United States)

    Saudi, Muhamad Hakimi; Mahali, Shalela Mohd; Harun, Fatimah Noor

    2017-08-01

    This paper discusses the development and the analytical solution of a mathematical model based on drug release system from a swelling delivery device. The mathematical model is represented by a one-dimensional advection-diffusion equation with nonhomogeneous moving boundary condition. The solution procedures consist of three major steps. Firstly, the application of steady state solution method, which is used to transform the nonhomogeneous moving boundary condition to homogeneous boundary condition. Secondly, the application of the Landau transformation technique that gives a significant impact in removing the advection term in the system of equation and transforming the moving boundary condition to a fixed boundary condition. Thirdly, the used of separation of variables method to find the analytical solution for the resulted initial boundary value problem. The results show that the swelling rate of delivery device and drug release rate is influenced by value of growth factor r.

  15. Extending the application range of a fuel performance code from normal operating to design basis accident conditions

    International Nuclear Information System (INIS)

    Van Uffelen, P.; Gyori, C.; Schubert, A.; Laar, J. van de; Hozer, Z.; Spykman, G.

    2008-01-01

    Two types of fuel performance codes are generally being applied, corresponding to the normal operating conditions and the design basis accident conditions, respectively. In order to simplify the code management and the interface between the codes, and to take advantage of the hardware progress it is favourable to generate a code that can cope with both conditions. In the first part of the present paper, we discuss the needs for creating such a code. The second part of the paper describes an example of model developments carried out by various members of the TRANSURANUS user group for coping with a loss of coolant accident (LOCA). In the third part, the validation of the extended fuel performance code is presented for LOCA conditions, whereas the last section summarises the present status and indicates needs for further developments to enable the code to deal with reactivity initiated accident (RIA) events

  16. Co-occurrence of medical conditions: Exposing patterns through probabilistic topic modeling of snomed codes.

    Science.gov (United States)

    Bhattacharya, Moumita; Jurkovitz, Claudine; Shatkay, Hagit

    2018-04-12

    Patients associated with multiple co-occurring health conditions often face aggravated complications and less favorable outcomes. Co-occurring conditions are especially prevalent among individuals suffering from kidney disease, an increasingly widespread condition affecting 13% of the general population in the US. This study aims to identify and characterize patterns of co-occurring medical conditions in patients employing a probabilistic framework. Specifically, we apply topic modeling in a non-traditional way to find associations across SNOMED-CT codes assigned and recorded in the EHRs of >13,000 patients diagnosed with kidney disease. Unlike most prior work on topic modeling, we apply the method to codes rather than to natural language. Moreover, we quantitatively evaluate the topics, assessing their tightness and distinctiveness, and also assess the medical validity of our results. Our experiments show that each topic is succinctly characterized by a few highly probable and unique disease codes, indicating that the topics are tight. Furthermore, inter-topic distance between each pair of topics is typically high, illustrating distinctiveness. Last, most coded conditions grouped together within a topic, are indeed reported to co-occur in the medical literature. Notably, our results uncover a few indirect associations among conditions that have hitherto not been reported as correlated in the medical literature. Copyright © 2018. Published by Elsevier Inc.

  17. Validation of a CFD code for Unsteady Flows with cyclic boundary Conditions

    International Nuclear Information System (INIS)

    Kim, Jong-Tae; Kim, Sang-Baik; Lee, Won-Jae

    2006-01-01

    Currently Lilac code is under development to analyze thermo-hydraulics of a high-temperature gas-cooled reactor (GCR). Interesting thermo-hydraulic phenomena in a nuclear reactor are usually unsteady and turbulent. The analysis of the unsteady flows by using a three dimension CFD code is time-consuming if the flow domain is very large. Hopefully, flow domains commonly encountered in the nuclear thermo-hydraulics is periodic. So it is better to use the geometrical characteristics in order to reduce the computational resources. To get the benefits from reducing the computation domains especially for the calculations of unsteady flows, the cyclic boundary conditions are implemented in the parallelized CFD code LILAC. In this study, the parallelized cyclic boundary conditions are validated by solving unsteady laminar and turbulent flows past a circular cylinder

  18. Geographic data: Zip Codes (Shape File)

    Data.gov (United States)

    Montgomery County of Maryland — This dataset contains all zip codes in Montgomery County. Zip codes are the postal delivery areas defined by USPS. Zip codes with mailboxes only are not included. As...

  19. Inclusion of models to describe severe accident conditions in the fuel simulation code DIONISIO

    Energy Technology Data Exchange (ETDEWEB)

    Lemes, Martín; Soba, Alejandro [Sección Códigos y Modelos, Gerencia Ciclo del Combustible Nuclear, Comisión Nacional de Energía Atómica, Avenida General Paz 1499, 1650 San Martín, Provincia de Buenos Aires (Argentina); Daverio, Hernando [Gerencia Reactores y Centrales Nucleares, Comisión Nacional de Energía Atómica, Avenida General Paz 1499, 1650 San Martín, Provincia de Buenos Aires (Argentina); Denis, Alicia [Sección Códigos y Modelos, Gerencia Ciclo del Combustible Nuclear, Comisión Nacional de Energía Atómica, Avenida General Paz 1499, 1650 San Martín, Provincia de Buenos Aires (Argentina)

    2017-04-15

    The simulation of fuel rod behavior is a complex task that demands not only accurate models to describe the numerous phenomena occurring in the pellet, cladding and internal rod atmosphere but also an adequate interconnection between them. In the last years several models have been incorporated to the DIONISIO code with the purpose of increasing its precision and reliability. After the regrettable events at Fukushima, the need for codes capable of simulating nuclear fuels under accident conditions has come forth. Heat removal occurs in a quite different way than during normal operation and this fact determines a completely new set of conditions for the fuel materials. A detailed description of the different regimes the coolant may exhibit in such a wide variety of scenarios requires a thermal-hydraulic formulation not suitable to be included in a fuel performance code. Moreover, there exist a number of reliable and famous codes that perform this task. Nevertheless, and keeping in mind the purpose of building a code focused on the fuel behavior, a subroutine was developed for the DIONISIO code that performs a simplified analysis of the coolant in a PWR, restricted to the more representative situations and provides to the fuel simulation the boundary conditions necessary to reproduce accidental situations. In the present work this subroutine is described and the results of different comparisons with experimental data and with thermal-hydraulic codes are offered. It is verified that, in spite of its comparative simplicity, the predictions of this module of DIONISIO do not differ significantly from those of the specific, complex codes.

  20. Obstetric Outcomes and Delivery-Related Health Care Utilization and Costs Among Pregnant Women With Multiple Chronic Conditions

    Science.gov (United States)

    Winkelman, Tyler N. A.; Heisler, Michele; Dalton, Vanessa K.

    2018-01-01

    Our objective was to measure obstetric outcomes and delivery-related health care utilization and costs among pregnant women with multiple chronic conditions. We used 2013–2014 data from the National Inpatient Sample to measure obstetric outcomes and delivery-related health care utilization and costs among women with no chronic conditions, 1 chronic condition, and multiple chronic conditions. Women with multiple chronic conditions were at significantly higher risk than women with 1 chronic condition or no chronic conditions across all outcomes measured. High-value strategies are needed to improve birth outcomes among vulnerable mothers and their infants. PMID:29420168

  1. Data delivery method based on neighbor nodes' information in a mobile ad hoc network.

    Science.gov (United States)

    Kashihara, Shigeru; Hayashi, Takuma; Taenaka, Yuzo; Okuda, Takeshi; Yamaguchi, Suguru

    2014-01-01

    This paper proposes a data delivery method based on neighbor nodes' information to achieve reliable communication in a mobile ad hoc network (MANET). In a MANET, it is difficult to deliver data reliably due to instabilities in network topology and wireless network condition which result from node movement. To overcome such unstable communication, opportunistic routing and network coding schemes have lately attracted considerable attention. Although an existing method that employs such schemes, MAC-independent opportunistic routing and encoding (MORE), Chachulski et al. (2007), improves the efficiency of data delivery in an unstable wireless mesh network, it does not address node movement. To efficiently deliver data in a MANET, the method proposed in this paper thus first employs the same opportunistic routing and network coding used in MORE and also uses the location information and transmission probabilities of neighbor nodes to adapt to changeable network topology and wireless network condition. The simulation experiments showed that the proposed method can achieve efficient data delivery with low network load when the movement speed is relatively slow.

  2. Data Delivery Method Based on Neighbor Nodes’ Information in a Mobile Ad Hoc Network

    Directory of Open Access Journals (Sweden)

    Shigeru Kashihara

    2014-01-01

    Full Text Available This paper proposes a data delivery method based on neighbor nodes’ information to achieve reliable communication in a mobile ad hoc network (MANET. In a MANET, it is difficult to deliver data reliably due to instabilities in network topology and wireless network condition which result from node movement. To overcome such unstable communication, opportunistic routing and network coding schemes have lately attracted considerable attention. Although an existing method that employs such schemes, MAC-independent opportunistic routing and encoding (MORE, Chachulski et al. (2007, improves the efficiency of data delivery in an unstable wireless mesh network, it does not address node movement. To efficiently deliver data in a MANET, the method proposed in this paper thus first employs the same opportunistic routing and network coding used in MORE and also uses the location information and transmission probabilities of neighbor nodes to adapt to changeable network topology and wireless network condition. The simulation experiments showed that the proposed method can achieve efficient data delivery with low network load when the movement speed is relatively slow.

  3. Projection of Patient Condition Code Distributions Based on Mechanism of Injury

    National Research Council Canada - National Science Library

    Zouris, James M; Walker, G. J; Blood, Christopher G

    2003-01-01

    The Medical Readiness and Strategic Plan 1998-2004 requires that the military services develop a method for linking real world patient load data with modern patient condition codes to enable planners...

  4. Nonsteady heat conduction code with radiation boundary conditions

    International Nuclear Information System (INIS)

    Fillo, J.A.; Benenati, R.; Powell, J.

    1975-01-01

    A heat-transfer model for studying the temperature build-up in graphite blankets for fusion reactors is presented. In essence, the computer code developed is for two-dimensional, nonsteady heat conduction in heterogeneous, anisotropic solids with nonuniform internal heating. Thermal radiation as well as bremsstrahlung radiation boundary conditions are included. Numerical calculations are performed for two design options by varying the wall loading, bremsstrahlung, surface layer thickness and thermal conductivity, blanket dimensions, time step and grid size. (auth)

  5. A simple blowdown code for SUPER-SARA loop conditions

    International Nuclear Information System (INIS)

    Fritz, G.

    1981-01-01

    The Super Sara test programme (SSTP) is aimed to study in pile the fuel and cluster behaviour under two types of accident conditions: - the ''Large break loss of coolant'' condition (LB-Loca), - the ''Severe fuel damage'' (SFD) in a boildown caused by a small break. BIVOL was developed for the LB-Loca situation. This code is made for a loop where essentially two volumes define the thermohydraulics during the blowdown. In the SUPERSARA loop these two volumes are represented by the hot leg and cold leg pipings together with the respective upper and lower plenum of the test section

  6. The weight hierarchies and chain condition of a class of codes from varieties over finite fields

    Science.gov (United States)

    Wu, Xinen; Feng, Gui-Liang; Rao, T. R. N.

    1996-01-01

    The generalized Hamming weights of linear codes were first introduced by Wei. These are fundamental parameters related to the minimal overlap structures of the subcodes and very useful in several fields. It was found that the chain condition of a linear code is convenient in studying the generalized Hamming weights of the product codes. In this paper we consider a class of codes defined over some varieties in projective spaces over finite fields, whose generalized Hamming weights can be determined by studying the orbits of subspaces of the projective spaces under the actions of classical groups over finite fields, i.e., the symplectic groups, the unitary groups and orthogonal groups. We give the weight hierarchies and generalized weight spectra of the codes from Hermitian varieties and prove that the codes satisfy the chain condition.

  7. A study on the numerical instability of COBRA-series subchannel analysis codes at low-pressure and low-flow conditions

    International Nuclear Information System (INIS)

    Yoo, Y. J.; Hwnag, T. H.; Kim, K. K.; Ji, S. K.

    2001-01-01

    The numerical instability at low-pressure and low-flow conditions has been confirmed to be the common problem of the existing COBRA-series subchannel analysis codes. In addition, the range of operating conditions at which the analyses by the codes are impossible has been evaluated. To evaluate the MATRA's inapplicable range of operating conditions of the SMART core that is to be operated at the low flow condition, i.e. about 30% of the flow of the existing commercial pressurized water reactors at the steady-state condition, the analyses of various operating conditions were performed by using several representative COBRA-series subchannel analysis codes including MATRA. TORC of CE, COBRA3CP of Siemens/KWU, COBRA4I of PNL, and MATRA of KAERI were chosen as the subchannel analysis codes to be evaluated. The various operating conditions used in the CHF tests carried out at the Winfrith Establishment of UKAEA were chosen as the conditions to be analyzed. As the result, the numerical instabilities at low-pressure and low-flow conditions occurred in the analyses by all of the codes. It was revealed that the MATRA code, which numerically more stable thatn the other codes, was not able to analyze the conditions of the pressure not more than 100 bar and the mass velocity not more than 300 kg/sec-m 2 . Hereafter it is required to find out the exact reason for the numerical instability of the existing COBRA-series subchannel analysis codes at low-pressure and low-flow conditions and to devise the new method to get over that numerical problem

  8. Implementation of decommissioning materials conditional clearance process to the OMEGA calculation code

    International Nuclear Information System (INIS)

    Zachar, Matej; Necas, Vladimir; Daniska, Vladimir

    2011-01-01

    The activities performed during nuclear installation decommissioning process inevitably lead to the production of large amount of radioactive material to be managed. Significant part of materials has such low radioactivity level that allows them to be released to the environment without any restriction for further use. On the other hand, for materials with radioactivity slightly above the defined unconditional clearance level, there is a possibility to release them conditionally for a specific purpose in accordance with developed scenario assuring that radiation exposure limits for population not to be exceeded. The procedure of managing such decommissioning materials, mentioned above, could lead to recycling and reuse of more solid materials and to save the radioactive waste repository volume. In the paper an a implementation of the process of conditional release to the OMEGA Code is analyzed in details; the Code is used for calculation of decommissioning parameters. The analytical approach in the material parameters assessment, firstly, assumes a definition of radiological limit conditions, based on the evaluation of possible scenarios for conditionally released materials, and their application to appropriate sorter type in existing material and radioactivity flow system. Other calculation procedures with relevant technological or economical parameters, mathematically describing e.g. final radiation monitoring or transport outside the locality, are applied to the OMEGA Code in the next step. Together with limits, new procedures creating independent material stream allow evaluation of conditional material release process during decommissioning. Model calculations evaluating various scenarios with different input parameters and considering conditional release of materials to the environment are performed to verify the implemented methodology. Output parameters and results of the model assessment are presented, discussed and conduced in the final part of the paper

  9. Optimization of conditions for gene delivery system based on PEI

    Directory of Open Access Journals (Sweden)

    Roya Cheraghi

    2017-01-01

    Full Text Available Objective(s: PEI based nanoparticle (NP due to dual capabilities of proton sponge and DNA binding is known as powerful tool for nucleic acid delivery to cells. However, serious cytotoxicity and complicated conditions, which govern NPs properties and its interactions with cells practically, hindered achievement to high transfection efficiency. Here, we have tried to optimize the properties of PEI/ firefly luciferase plasmid complexes and cellular condition to improve transfection efficiency. Materials and Methods: For this purpose, firefly luciferase, as a robust gene reporter, was complexed with PEI to prepare NPs with different size and charge. The physicochemical properties of nanoparticles were evaluated using agarose gel retardation and dynamic light scattering.  MCF7 and BT474 cells at different confluency were also transfected with prepared nanoparticles at various concentrations for short and long times. Results: The branched PEI can instantaneously bind to DNA and form cationic NPs. The results demonstrated the production of nanoparticles with size about 100-500 nm dependent on N/P ratio. Moreover, increase of nanoparticles concentration on the cell surface drastically improved the transfection rate, so at a concentration of 30 ng/ìl, the highest transfection efficiency was achieved. On the other side, at confluency between 40-60%, the maximum efficiency was obtained. The result demonstrated that N/P ratio of 12 could establish an optimized ratio between transfection efficiency and cytotoxicity of PEI/plasmid nanoparticles. The increase of NPs N/P ratio led to significant cytotoxicity. Conclusion: Obtained results verified the optimum conditions for PEI based gene delivery in different cell lines.

  10. Automated delivery of codes for charge in radiotherapy

    International Nuclear Information System (INIS)

    Sauer, Michael; Volz, Steffen; Hall, Markus; Roehner, Fred; Frommhold, Hermann; Grosu, Anca-Ligia; Heinemann, Felix

    2010-01-01

    Background and purpose: for the medical billing of Radiotherapy every fraction has to be encoded, including date and time of all administered treatments. With fractions averaging 30 per patient and about 2,500 new patients every year the number of Radiotherapy codes reaches an amount of 70,000 and more. Therefore, an automated proceeding for transferring and processing therapy codes has been developed at the Department of Radiotherapy Freiburg, Germany. This is a joint project of the Department of Radiotherapy, the Administration Department, and the Central II Department of the University Hospital of Freiburg. Material and methods: the project consists of several modules whose collaboration makes the projected automated transfer of treatment codes possible. The first step is to extract the data from the department's Clinical Information System (MOSAIQ). These data are transmitted to the Central IT Department via an HL7 interface, where a check for corresponding hospitalization data is performed. In the further processing of the data, a matching table plays an important role allowing the transformation of a treatment code into a valid medical billing code. In a last step, the data are transferred to the medical billing system. Results and conclusion: after assembling and implementing the particular modules successfully, a first beta test was launched. In order to test the modules separately as well as the interaction of the components, extensive tests were performed during March 2006. Soon it became clear that the tested procedure worked efficiently and accurately. In April 2006, a pilot project with a few qualities of treatment (e.g., computed tomography, simulation) was put into practice. Since October 2006, nearly all Radiation Therapy codes (∝ 75,000) are being transferred to the comprehensive Hospital Information System (HIS) automatically in a daily routine. (orig.)

  11. RODSWELL: a computer code for the thermomechanical analysis of fuel rods under LOCA conditions

    International Nuclear Information System (INIS)

    Casadei, F.; Laval, H.; Donea, J.; Jones, P.M.; Colombo, A.

    1984-01-01

    The present report is the user's manual for the computer code RODSWELL developed at the JRC-Ispra for the thermomechanical analysis of LWR fuel rods under simulated loss-of-coolant accident (LOCA) conditions. The code calculates the variation in space and time of all significant fuel rod variables, including fuel, gap and cladding temperature, fuel and cladding deformation, cladding oxidation and rod internal pressure. The essential characteristics of the code are briefly outlined here. The model is particularly designed to perform a full thermal and mechanical analysis in both the azimuthal and radial directions. Thus, azimuthal temperature gradients arising from pellet eccentricity, flux tilt, arbitrary distribution of heat sources in the fuel and the cladding and azimuthal variation of coolant conditions can be treated. The code combines a transient 2-dimensional heat conduction code and a 1-dimentional mechanical model for the cladding deformation. The fuel rod is divided into a number of axial sections and a detailed thermomechanical analysis is performed within each section in radial and azimuthal directions. In the following sections, instructions are given for the definition of the data files and the semi-variable dimensions. Then follows a complete description of the input data. Finally, the restart option is described

  12. Modelling of WWER fuel rod during LOCA conditions using FEM code ANSYS

    International Nuclear Information System (INIS)

    Bogatyr, S. M.; Krupkin, A. V.; Kuznetsov, V. I.; Novikov, V. V.; Petrov, O. M.; Shestopalov, A. A.

    2013-01-01

    The report presents the results of the computer simulation of the IFA-650.6 experiment, the sixth test in Halden LOCA test project series, performed in May 18, 2007 with a pre-irradiated WWER-440 fuel with maximum burnup of 56 MWd/kgU. The thermo-mechanical analysis was fulfilled with the license finite element ANSYS code package.The calculation was carried out with the 2D axisymmetric and 3D problem definitions. Analysis of the calculational results shows that the ANSYS code can adequately simulate thermo-mechanical behavior of cladding under IFA-650.6 test conditions. (authors)

  13. A computer code simulating multistage chemical exchange column under wide range of operating conditions

    International Nuclear Information System (INIS)

    Yamanishi, Toshihiko; Okuno, Kenji

    1996-09-01

    A computer code has been developed to simulate a multistage CECE(Combined Electrolysis Chemical Exchange) column. The solution of basic equations can be found out by the Newton-Raphson method. The independent variables are the atom fractions of D and T in each stage for the case where H is dominant within the column. These variables are replaced by those of H and T under the condition that D is dominant. Some effective techniques have also been developed to get a set of solutions of the basic equations: a setting procedure of initial values of the independent variables; and a procedure for the convergence of the Newton-Raphson method. The computer code allows us to simulate the column behavior under a wide range of the operating conditions. Even for a severe case, where the dominant species changes along the column height, the code can give a set of solutions of the basic equations. (author)

  14. FARST: A computer code for the evaluation of FBR fuel rod behavior under steady-state/transient conditions

    International Nuclear Information System (INIS)

    Nakamura, M.; Sakagami, M.

    1984-01-01

    FARST, a computer code for the evaluation of fuel rod thermal and mechanical behavior under steady-state/transient conditions has been developed. The code characteristics are summarized as follows: (I) FARST evaluates the fuel rod behavior under the transient conditions. The code analyzes thermal and mechanical phenomena within a fuel rod, taking into account the temperature change in coolant surrounding the fuel rod. (II) Permanent strains such as plastic, creep and swelling strains as well as thermoelastic deformations can be analyzed by using the strain increment method. (III) Axial force and contact pressure which act on the fuel stack and cladding are analyzed based on the stick/slip conditions. (IV) FARST used a pellet swelling model which depends on the contact pressure between pellet and cladding, and an empirical pellet relocation model, designated as 'jump relocation model'. The code was successfully applied to analyses of the fuel rod irradiation data from pulse reactor for nuclear safety research in Cadarache (CABRI) and pulse reactor for nuclear safety research in Japan Atomic Energy Research Institute (NSRR). The code was further applied to stress analysis of a 1000 MW class large FBR plant fuel rod during transient conditions. The steady-state model which was used so far gave the conservative results for cladding stress during overpower transient, but underestimated the results for cladding stress during a rapid temperature decrease of coolant. (orig.)

  15. VT ZIP Code Areas

    Data.gov (United States)

    Vermont Center for Geographic Information — (Link to Metadata) A ZIP Code Tabulation Area (ZCTA) is a statistical geographic entity that approximates the delivery area for a U.S. Postal Service five-digit...

  16. SSYST, a code-system for analysing transient LWR fuel rod behaviour under off-normal conditions

    International Nuclear Information System (INIS)

    Borgwaldt, H.; Gulden, W.

    1983-01-01

    SSYST is a code-system for analysing transient fuel rod behaviour under off-normal conditions, developed conjointly by the Institut fuer Kernenergetik und Energiesysteme (IKE), Stuttgart, and Kernforschungszentrum Karlsruhe (KfK) under contract of Projek Nukleare Sicherheit (PNS) at KfK. The main differences between SSYST and similar codes are (1) an open-ended modular code organisation, and (2) a preference for simple models, wherever possible. While the first feature makes SSYST a very flexible tool, easily adapted to changing requirements, the second feature leads to short execution times. The analysis of transient rod behaviour under LOCA boundary conditions takes 2 min cpu-time (IBM-3033), so that extensive parametric studies become possible. This paper gives an outline of the overall code organisation and a general overview of the physical models implemented. Besides explaining the routine application of SSYST in the analysis of loss-of-coolant accidents, examples are given of special applications which have led to a satisfactory understanding of the decisive influence of deviations from rotational symmetry on the fuel rod perimeter. (author)

  17. SSYST: A code-system for analyzing transient LWR fuel rod behaviour under off-normal conditions

    International Nuclear Information System (INIS)

    Borgwaldt, H.; Gulden, W.

    1983-01-01

    SSYST is a code-system for analyzing transient fuel rod behaviour under off-normal conditions, developed conjointly by the Institut fur Kernenergetik und Energiesysteme (IKE), Stuttgart, and Kernforschungszentrum Karlsruhe (KfK) under contract of Projekt Nukleare Sicherheit (PNS) at KfK. The main differences between SSYST and similar codes are an open-ended modular code organization, and a preference for simple models, wherever possible. While the first feature makes SSYST a very flexible tool, easily adapted to changing requirements, the second feature leads to short execution times. The analysis of transient rod behaviour under LOCA boundary conditions takes 2 min cpu-time (IBM-3033), so that extensive parametric studies become possible. This paper gives an outline of the overall code organisation and a general overview of the physical models implemented. Besides explaining the routine application of SSYST in the analysis of loss-of-coolant accidents, examples are given of special applications which have led to a satisfactory understanding of the decisive influence of deviations from rotational symmetry on the fuel rod perimeter

  18. Is preterm delivery still related to physical working conditions in pregnancy?

    OpenAIRE

    Saurel-Cubizolles, M J; Subtil, D; Kaminski, M

    1991-01-01

    STUDY OBJECTIVE--The aim was to determine the relationship between working conditions during pregnancy, women's occupation, and preterm birth. DESIGN--This was a retrospective survey. SETTING--The study was carried out in four public maternity units in France in 1987 and 1988. SUBJECTS--1949 women were interviewed after the delivery during their stay in hospital. Of these, 1002 held a job during pregnancy, but this report is confined to 875 women who had a single live birth and who had worked...

  19. "Hour of Code": A Case Study

    Science.gov (United States)

    Du, Jie; Wimmer, Hayden; Rada, Roy

    2018-01-01

    This study investigates the delivery of the "Hour of Code" tutorials to college students. The college students who participated in this study were surveyed about their opinion of the Hour of Code. First, the students' comments were discussed. Next, a content analysis of the offered tutorials highlights their reliance on visual…

  20. Accuracy of ICD-10 Coding System for Identifying Comorbidities and Infectious Conditions Using Data from a Thai University Hospital Administrative Database.

    Science.gov (United States)

    Rattanaumpawan, Pinyo; Wongkamhla, Thanyarak; Thamlikitkul, Visanu

    2016-04-01

    To determine the accuracy of International Statistical Classification of Disease and Related Health Problems, 10th Revision (ICD-10) coding system in identifying comorbidities and infectious conditions using data from a Thai university hospital administrative database. A retrospective cross-sectional study was conducted among patients hospitalized in six general medicine wards at Siriraj Hospital. ICD-10 code data was identified and retrieved directly from the hospital administrative database. Patient comorbidities were captured using the ICD-10 coding algorithm for the Charlson comorbidity index. Infectious conditions were captured using the groups of ICD-10 diagnostic codes that were carefully prepared by two independent infectious disease specialists. Accuracy of ICD-10 codes combined with microbiological dataf or diagnosis of urinary tract infection (UTI) and bloodstream infection (BSI) was evaluated. Clinical data gathered from chart review was considered the gold standard in this study. Between February 1 and May 31, 2013, a chart review of 546 hospitalization records was conducted. The mean age of hospitalized patients was 62.8 ± 17.8 years and 65.9% of patients were female. Median length of stay [range] was 10.0 [1.0-353.0] days and hospital mortality was 21.8%. Conditions with ICD-10 codes that had good sensitivity (90% or higher) were diabetes mellitus and HIV infection. Conditions with ICD-10 codes that had good specificity (90% or higher) were cerebrovascular disease, chronic lung disease, diabetes mellitus, cancer HIV infection, and all infectious conditions. By combining ICD-10 codes with microbiological results, sensitivity increased from 49.5 to 66%for UTI and from 78.3 to 92.8%for BS. The ICD-10 coding algorithm is reliable only in some selected conditions, including underlying diabetes mellitus and HIV infection. Combining microbiological results with ICD-10 codes increased sensitivity of ICD-10 codes for identifying BSI. Future research is

  1. Modeling of the WWER-1000 fuel-rod behavior in steady-state condition with FRAPCONE-3 computer code

    International Nuclear Information System (INIS)

    Andreeva, Marina; Totev, Totju; Stoyanov, Stoyan

    2008-01-01

    It is presented within the paper the results of the modeling and the assessment of the integral code predictions of the WWER fuel-rod behavior in steady-state condition. The assessments in this paper have used the MASSIH and ANS 5.4 subroutine in the code. The modeling and calculations have been performed with FRAPCONE-3 computer code in Argonne National Laboratory, USA

  2. Synchronized moving aperture radiation therapy (SMART): superimposing tumor motion on IMRT MLC leaf sequences under realistic delivery conditions

    International Nuclear Information System (INIS)

    Xu Jun; Papanikolaou, Nikos; Shi Chengyu; Jiang, Steve B

    2009-01-01

    Synchronized moving aperture radiation therapy (SMART) has been proposed to account for tumor motions during radiotherapy in prior work. The basic idea of SMART is to synchronize the moving radiation beam aperture formed by a dynamic multileaf collimator (DMLC) with the tumor motion induced by respiration. In this paper, a two-dimensional (2D) superimposing leaf sequencing method is presented for SMART. A leaf sequence optimization strategy was generated to assure the SMART delivery under realistic delivery conditions. The study of delivery performance using the Varian LINAC and the Millennium DMLC showed that clinical factors such as collimator angle, dose rate, initial phase and machine tolerance affect the delivery accuracy and efficiency. An in-house leaf sequencing software was developed to implement the 2D superimposing leaf sequencing method and optimize the motion-corrected leaf sequence under realistic clinical conditions. The analysis of dynamic log (Dynalog) files showed that optimization of the leaf sequence for various clinical factors can avoid beam hold-offs which break the synchronization of SMART and fail the SMART dose delivery. Through comparison between the simulated delivered fluence map and the planed fluence map, it was shown that the motion-corrected leaf sequence can greatly reduce the dose error.

  3. Computer code calculations of the TMI-2 accident: initial and boundary conditions

    International Nuclear Information System (INIS)

    Behling, S.R.

    1985-05-01

    Initial and boundary conditions during the Three Mile Island Unit 2 (TMI-2) accident are described and detailed. A brief description of the TMI-2 plant configuration is given. Important contributions to the progression of the accident in the reactor coolant system are discussed. Sufficient information is provided to allow calculation of the TMI-2 accident with computer codes

  4. Code of ethics: principles for ethical leadership.

    Science.gov (United States)

    Flite, Cathy A; Harman, Laurinda B

    2013-01-01

    The code of ethics for a professional association incorporates values, principles, and professional standards. A review and comparative analysis of a 1934 pledge and codes of ethics from 1957, 1977, 1988, 1998, 2004, and 2011 for a health information management association was conducted. Highlights of some changes in the healthcare delivery system are identified as a general context for the codes of ethics. The codes of ethics are examined in terms of professional values and changes in the language used to express the principles of the various codes.

  5. Code Cactus; Code Cactus

    Energy Technology Data Exchange (ETDEWEB)

    Fajeau, M; Nguyen, L T; Saunier, J [Commissariat a l' Energie Atomique, Centre d' Etudes Nucleaires de Saclay, 91 - Gif-sur-Yvette (France)

    1966-09-01

    This code handles the following problems: -1) Analysis of thermal experiments on a water loop at high or low pressure; steady state or transient behavior; -2) Analysis of thermal and hydrodynamic behavior of water-cooled and moderated reactors, at either high or low pressure, with boiling permitted; fuel elements are assumed to be flat plates: - Flowrate in parallel channels coupled or not by conduction across plates, with conditions of pressure drops or flowrate, variable or not with respect to time is given; the power can be coupled to reactor kinetics calculation or supplied by the code user. The code, containing a schematic representation of safety rod behavior, is a one dimensional, multi-channel code, and has as its complement (FLID), a one-channel, two-dimensional code. (authors) [French] Ce code permet de traiter les problemes ci-dessous: 1. Depouillement d'essais thermiques sur boucle a eau, haute ou basse pression, en regime permanent ou transitoire; 2. Etudes thermiques et hydrauliques de reacteurs a eau, a plaques, a haute ou basse pression, ebullition permise: - repartition entre canaux paralleles, couples on non par conduction a travers plaques, pour des conditions de debit ou de pertes de charge imposees, variables ou non dans le temps; - la puissance peut etre couplee a la neutronique et une representation schematique des actions de securite est prevue. Ce code (Cactus) a une dimension d'espace et plusieurs canaux, a pour complement Flid qui traite l'etude d'un seul canal a deux dimensions. (auteurs)

  6. KUPOL-M code for simulation of the VVER's accident localization system under LOCA conditions

    International Nuclear Information System (INIS)

    Efanov, A.D.; Lukyanov, A.A.; Shangin, N.N.; Zajtsev, A.A.; Solov'ev, S.L.

    2004-01-01

    Computer code KUPOL-M is developed for analysis of thermodynamic parameters of medium within full pressure containment for NPPs with VVER under LOCA conditions. The analysis takes into account the effects of non-stationary heat-mass transfer of gas-drop mixture in the containment compartments with natural convection, volume and surface steam condensation in the presence of noncondensables, heat-mass exchange of the compartment atmosphere with water in the sumps. The operation of the main safety systems like a spray system, hydrogen catalytic recombiners, emergency core cooling pumps, valves and a fan system is simulated in KUPOL-M code. The main results of the code verification including the ones of the participation in ISP-47 International Standard Problem on containment thermal-hydraulics are presented. (author)

  7. Determining astronomical seeing conditions at Matjiesfontein by optical and turbulence methods

    Energy Technology Data Exchange (ETDEWEB)

    Nickola, M [Hartebeesthoek Radio Astronomy Observatory (HartRAO) Space Geodesy Programme, PO Box 443, Krugersdorp 1740 (South Africa); Esau, I [G.C. Rieber Climate Institute of the Nansen Environmental and Remote Sensing Center (NERSC), Thoermohlensgate 47, N-5006 Bergen (Norway); Djolov, G [University of Pretoria, Department of Geography, Geoinformatics and Meteorology, Faculty of Natural and Agricultural Sciences, University of Pretoria, Pretoria 0002 (South Africa)

    2010-08-15

    Matjiesfontein in the Karoo has been proposed as a suitable location for a new fundamental space geodetic observatory. On-site geodetic equipment will include a Lunar Laser Ranger (LLR). LLR requires sub-arcsecond optical seeing conditions for delivery of high quality and quantity data. Seeing conditions at the Matjiesfontein site will be evaluated by making use of an automated seeing monitor and by modelling atmospheric turbulence with Large Eddy Simulation Nansen Center Improved Code (LESNIC).

  8. Coding paediatric outpatient data to provide health planners with information on children with chronic conditions and disabilities.

    Science.gov (United States)

    Craig, Elizabeth; Kerr, Neal; McDonald, Gabrielle

    2017-03-01

    In New Zealand, there is a paucity of information on children with chronic conditions and disabilities (CCD). One reason is that many are managed in hospital outpatients where diagnostic coding of health-care events does not occur. This study explores the feasibility of coding paediatric outpatient data to provide health planners with information on children with CCD. Thirty-seven clinicians from six District Health Boards (DHBs) trialled coding over 12 weeks. In five DHBs, the International Classification of Diseases and Related Health Problems, 10th Edition, Australian Modification (ICD-10-AM) and Systematised Nomenclature of Medicine Clinical Terms (SNOMED-CT) were trialled for 6 weeks each. In one DHB, ICD-10-AM was trialled for 12 weeks. A random sample (30%) of ICD-10-AM coded events were also coded by clinical coders. A mix of paper and electronic methods were used. In total 2,604 outpatient events were coded in ICD-10-AM and 693 in SNOMED-CT. Dual coding occurred for 770 (29.6%) ICD-10-AM events. Overall, 34% of ICD-10-AM and 40% of SNOMED-CT events were for developmental and behavioural disorders. Chronic medical conditions were also common. Clinicians were concerned about the workload impacts, particularly for paper-based methods. Coder's were concerned about clinician's adherence to coding guidelines and the poor quality of documentation in some notes. Coded outpatient data could provide planners with a rich source of information on children with CCD. However, coding is also resource intensive. Thus its costs need to be weighed against the costs of managing a much larger health budget using very limited information. © 2016 Paediatrics and Child Health Division (The Royal Australasian College of Physicians).

  9. Beam Delivery Simulation: BDSIM - Development & Optimization

    CERN Document Server

    Nevay, Laurence James; Garcia-Morales, H; Gibson, S M; Kwee-Hinzmann, R; Snuverink, J; Deacon, L C

    2014-01-01

    Beam Delivery Simulation (BDSIM) is a Geant4 and C++ based particle tracking code that seamlessly tracks particles through accelerators and detectors, including the full range of particle interaction physics processes from Geant4. BDSIM has been successfully used to model beam loss and background conditions for many current and future linear accelerators such as the Accelerator Test Facility 2 (ATF2) and the International Linear Collider (ILC). Current developments extend its application for use with storage rings, in particular for the Large Hadron Collider (LHC) and the High Luminosity upgrade project (HL-LHC). This paper presents the latest results from using BDSIM to model the LHC as well as the developments underway to improve performance.

  10. Validation of the TRACR3D code for soil water flow under saturated/unsaturated conditions in three experiments

    International Nuclear Information System (INIS)

    Perkins, B.; Travis, B.; DePoorter, G.

    1985-01-01

    Validation of the TRACR3D code in a one-dimensional form was obtained for flow of soil water in three experiments. In the first experiment, a pulse of water entered a crushed-tuff soil and initially moved under conditions of saturated flow, quickly followed by unsaturated flow. In the second experiment, steady-state unsaturated flow took place. In the final experiment, two slugs of water entered crushed tuff under field conditions. In all three experiments, experimentally measured data for volumetric water content agreed, within experimental errors, with the volumetric water content predicted by the code simulations. The experiments and simulations indicated the need for accurate knowledge of boundary and initial conditions, amount and duration of moisture input, and relevant material properties as input into the computer code. During the validation experiments, limitations on monitoring of water movement in waste burial sites were also noted. 5 references, 34 figures, 9 tables

  11. Safe use of mine winding ropes, volume 4: studies towards a code of practice for rope condition assessment.

    CSIR Research Space (South Africa)

    Borrello, M

    1996-06-01

    Full Text Available The aim of this investigation was the verification of the code of Practice for Rope Condition Assessment. Ropes were meant to be discarded according to the discard criteria as outlined in the code and then tested by the CSIR. The results...

  12. Validation of the ASSERT subchannel code for MAPLE-X10 reactor conditions

    International Nuclear Information System (INIS)

    Carver, M.B.; Kiteley, J.C.; Junop, S.V.; Wasilewicz, J.F.

    1993-01-01

    The ASSERT subchannel analysis code has been developed specifically to model flow and phase distributions within CANDU fuel channels. Recently, ASSERT has been adapted for use in simulating the MAPLE-X10 reactor. ASSERT uses an advanced drift-flux model, which permits the phases to have unequal velocities and unequal temperatures (UVUT), and thus can model non-equilibrium effects such as phase separation tendencies and subcooled boiling. Modelling subcooled boiling accurately is particularly important for MAPLE-X10. This paper briefly summarizes the non-equilibrium model used in the ASSERT code, the equations used to represent these models, and the algorithms used to solve the equations numerically. Very few modifications to the ASSERT models were needed to address MAPLE conditions. These centered on the manner in which finned fuel rods are treated, and they are discussed in the paper. The paper also gives results from validation exercises, in which the ASSERT code predictions of subcooled boiling void-fraction and critical heat flux were compared to experiments using MAPLE-X10 finned fuel elements in annuli and various bundles. 18 refs., 13 figs., 3 tabs

  13. Basic requirements of mechanical properties for nuclear pressure vessel materials in ASME-BPV code

    International Nuclear Information System (INIS)

    Ning Dong; Yao Weida

    2011-01-01

    The four basic aspects of strengths, ductility, toughness and fatigue strengths can be summarized for overall mechanical properties requirements of materials for nuclear pressure-retaining vessels in ASME-BPV code. These mechanical property indexes involve in the factors of melting, manufacture, delivery conditions, check or recheck for mechanical properties and chemical compositions, etc. and relate to degradation and damage accumulation during the use of materials. This paper specifically accounts for the basic requirements and theoretic basis of mechanical properties for nuclear pressure vessel materials in ASME-BPV code and states the internal mutual relationships among the four aspects of mechanical properties. This paper focuses on putting forward at several problems on mechanical properties of materials that shall be concerned about during design and manufacture for nuclear pressure vessels according to ASME-BPV code. (author)

  14. 20 CFR 662.430 - Under what conditions may One-Stop operators designated to operate in a One-Stop delivery system...

    Science.gov (United States)

    2010-04-01

    ... designated to operate in a One-Stop delivery system established prior to the enactment of WIA be designated... DESCRIPTION OF THE ONE-STOP SYSTEM UNDER TITLE I OF THE WORKFORCE INVESTMENT ACT One-Stop Operators § 662.430 Under what conditions may One-Stop operators designated to operate in a One-Stop delivery system...

  15. Providing thermal-hydraulic boundary conditions to the reactor code TINTE through a Flownex-TINTE coupling - HTR2008-58110

    International Nuclear Information System (INIS)

    Marais, D.; Greyvenstein, G. P.

    2008-01-01

    TINTE is a well established reactor analysis code which models the transient behaviour of pebble bed reactor cores but it does not include the capabilities to model a power conversion unit (PCU). This raises the issue that TINTE cannot model full system transients. One way to overcome this problem is to supply TINTE with time-dependant thermal-hydraulic boundary conditions which are obtained from PCU simulations. This study investigates a method to provide boundary conditions for the nuclear code TINTE during full system transients. This was accomplished by creating a high level interface between the systems CFD code Flownex and TINTE. An indirect coupling method is explored whereby characteristics of the PCU are matched to characteristics of the nuclear core. This method eliminates the need to iterate between the two codes. A number of transients are simulated using the coupled code and then compared against stand-alone Flownex simulations. The coupling method introduces relatively small errors when reproducing mass flow, temperature and pressure in steady state analysis, but become more pronounced when dealing with fast thermal-hydraulic transients. Decreasing the maximum time step length of TINTE reduces this problem, but increases the computational time. Copyright ASME 2008. (authors)

  16. Self-complementary circular codes in coding theory.

    Science.gov (United States)

    Fimmel, Elena; Michel, Christian J; Starman, Martin; Strüngmann, Lutz

    2018-04-01

    Self-complementary circular codes are involved in pairing genetic processes. A maximal [Formula: see text] self-complementary circular code X of trinucleotides was identified in genes of bacteria, archaea, eukaryotes, plasmids and viruses (Michel in Life 7(20):1-16 2017, J Theor Biol 380:156-177, 2015; Arquès and Michel in J Theor Biol 182:45-58 1996). In this paper, self-complementary circular codes are investigated using the graph theory approach recently formulated in Fimmel et al. (Philos Trans R Soc A 374:20150058, 2016). A directed graph [Formula: see text] associated with any code X mirrors the properties of the code. In the present paper, we demonstrate a necessary condition for the self-complementarity of an arbitrary code X in terms of the graph theory. The same condition has been proven to be sufficient for codes which are circular and of large size [Formula: see text] trinucleotides, in particular for maximal circular codes ([Formula: see text] trinucleotides). For codes of small-size [Formula: see text] trinucleotides, some very rare counterexamples have been constructed. Furthermore, the length and the structure of the longest paths in the graphs associated with the self-complementary circular codes are investigated. It has been proven that the longest paths in such graphs determine the reading frame for the self-complementary circular codes. By applying this result, the reading frame in any arbitrary sequence of trinucleotides is retrieved after at most 15 nucleotides, i.e., 5 consecutive trinucleotides, from the circular code X identified in genes. Thus, an X motif of a length of at least 15 nucleotides in an arbitrary sequence of trinucleotides (not necessarily all of them belonging to X) uniquely defines the reading (correct) frame, an important criterion for analyzing the X motifs in genes in the future.

  17. INLUX-DBR - A calculation code to calculate indoor natural illuminance inside buildings under various sky conditions

    International Nuclear Information System (INIS)

    Ferraro, V.; Igawa, N.; Marinelli, V.

    2010-01-01

    A calculation code, named INLUX-DBR, is presented, which is a modified version of INLUX code, able to predict the illuminance distribution on the inside surfaces of a room with six walls and a window, and on the work plane. At each desired instant the code solves the system of the illuminance equations of each surface element, characterized by the latter's reflection coefficient and its view factors toward the other elements. In the model implemented in the code, the sky-diffuse luminance distribution, the sun beam light and the light reflected from the ground toward the room are considered. The code was validated by comparing the calculated values of illuminance with the experimental values measured inside a scale model (1:5) of a building room, in various sky conditions of overcast, clear and intermediate days. The validation is performed using the sky luminance data measured by a sky scanner and the measured beam illuminance of the sun as input data. A comparative analysis of some of the well-known calculation models of sky luminance, namely Perez, Igawa and CIE models was also carried out, comparing the code predictions and the measured values of inside illuminance in the scale model.

  18. 43 CFR 418.28 - Conditions of delivery.

    Science.gov (United States)

    2010-10-01

    ... particulars including the known or estimated location and amounts; (3) The amount will not be included as a valid headgate delivery for purposes of computing the Project efficiency and resultant incentive credit... treated directly as a debit to Lahontan storage in the same manner as an efficiency debit. (b) District...

  19. A bar coding system for environmental projects

    International Nuclear Information System (INIS)

    Barber, R.B.; Hunt, B.J.; Burgess, G.M.

    1988-01-01

    This paper presents BeCode systems, a bar coding system which provides both nuclear and commercial clients with a data capture and custody management program that is accurate, timely, and beneficial to all levels of project operations. Using bar code identifiers is an essentially paperless and error-free method which provides more efficient delivery of data through its menu card-driven structure, which speeds collection of essential data for uploading to a compatible device. The effects of this sequence include real-time information for operator analysis, management review, audits, planning, scheduling, and cost control

  20. LFSC - Linac Feedback Simulation Code

    Energy Technology Data Exchange (ETDEWEB)

    Ivanov, Valentin; /Fermilab

    2008-05-01

    The computer program LFSC (Code>) is a numerical tool for simulation beam based feedback in high performance linacs. The code LFSC is based on the earlier version developed by a collective of authors at SLAC (L.Hendrickson, R. McEwen, T. Himel, H. Shoaee, S. Shah, P. Emma, P. Schultz) during 1990-2005. That code was successively used in simulation of SLC, TESLA, CLIC and NLC projects. It can simulate as pulse-to-pulse feedback on timescale corresponding to 5-100 Hz, as slower feedbacks, operating in the 0.1-1 Hz range in the Main Linac and Beam Delivery System. The code LFSC is running under Matlab for MS Windows operating system. It contains about 30,000 lines of source code in more than 260 subroutines. The code uses the LIAR ('Linear Accelerator Research code') for particle tracking under ground motion and technical noise perturbations. It uses the Guinea Pig code to simulate the luminosity performance. A set of input files includes the lattice description (XSIF format), and plane text files with numerical parameters, wake fields, ground motion data etc. The Matlab environment provides a flexible system for graphical output.

  1. PBMC: Pre-conditioned Backward Monte Carlo code for radiative transport in planetary atmospheres

    Science.gov (United States)

    García Muñoz, A.; Mills, F. P.

    2017-08-01

    PBMC (Pre-Conditioned Backward Monte Carlo) solves the vector Radiative Transport Equation (vRTE) and can be applied to planetary atmospheres irradiated from above. The code builds the solution by simulating the photon trajectories from the detector towards the radiation source, i.e. in the reverse order of the actual photon displacements. In accounting for the polarization in the sampling of photon propagation directions and pre-conditioning the scattering matrix with information from the scattering matrices of prior (in the BMC integration order) photon collisions, PBMC avoids the unstable and biased solutions of classical BMC algorithms for conservative, optically-thick, strongly-polarizing media such as Rayleigh atmospheres.

  2. Development of an Information Delivery Manual for Early Stage BIM-based Energy Performance Assessment and Code Compliance as a Part of DGNB Pre-Certification

    DEFF Research Database (Denmark)

    Petrova, Ekaterina Aleksandrova; Romanska, Iva; Stamenov, Martin

    2017-01-01

    for all parties involved. However, the persistent lack of early collaboration and process standardization prevent reaching the full potential of BIM-based performance evaluation. By following buildingSMART’s methodology for development of Information Delivery Manual/Model View Definition, this paper...... presents a framework for BIM-based energy performance assessment and code compliance, as required by the Danish Building Regulations and the DGNB rating system. Standardization of the information exchange would increase efficiency and reduce manual data input, duplication of work and errors due...

  3. INLUX-DBR - A calculation code to calculate indoor natural illuminance inside buildings under various sky conditions

    Energy Technology Data Exchange (ETDEWEB)

    Ferraro, V.; Igawa, N.; Marinelli, V. [Mechanical Engineering Department, University of Calabria, 87036 Arcavacata di Rende (CS) (Italy)

    2010-09-15

    A calculation code, named INLUX-DBR, is presented, which is a modified version of INLUX code, able to predict the illuminance distribution on the inside surfaces of a room with six walls and a window, and on the work plane. At each desired instant the code solves the system of the illuminance equations of each surface element, characterized by the latter's reflection coefficient and its view factors toward the other elements. In the model implemented in the code, the sky-diffuse luminance distribution, the sun beam light and the light reflected from the ground toward the room are considered. The code was validated by comparing the calculated values of illuminance with the experimental values measured inside a scale model (1:5) of a building room, in various sky conditions of overcast, clear and intermediate days. The validation is performed using the sky luminance data measured by a sky scanner and the measured beam illuminance of the sun as input data. A comparative analysis of some of the well-known calculation models of sky luminance, namely Perez, Igawa and CIE models was also carried out, comparing the code predictions and the measured values of inside illuminance in the scale model. (author)

  4. SSYST. A code system to analyze LWR fuel rod behavior under accident conditions

    International Nuclear Information System (INIS)

    Gulden, W.; Meyder, R.; Borgwaldt, H.

    1982-01-01

    SSYST (Safety SYSTem) is a modular system to analyze the behavior of light water reactor fuel rods and fuel rod simulators under accident conditions. It has been developed in close cooperation between Kernforschungszentrum Karlsruhe (KfK) and the Institut fuer Kerntechnik und Energiewandlung (IKE), University Stuttgart, under contract of Projekt Nukleare Sicherheit (PNS) at KfK. Although originally aimed at single rod analysis, features are available to calculate effects such as blockage ratios of bundles and wholes cores. A number of inpile and out-of-pile experiments were used to assess the system. Main differences versus codes like FRAP-T with similar applications are (1) an open-ended modular code organisation, (2) availability of modules of different sophistication levels for the same physical processes, and (3) a preference for simple models, wherever possible. The first feature makes SSYST a very flexible tool, easily adapted to changing requirements; the second enables the user to select computational models adequate to the significance of the physical process. This leads together with the third feature to short execution times. The analysis of transient rod behavior under LOCA boundary conditions e.g. takes 2 mins cpu-time (IBM-3033), so that extensive parametric studies become possible

  5. LFSC - Linac Feedback Simulation Code

    International Nuclear Information System (INIS)

    Ivanov, Valentin; Fermilab

    2008-01-01

    The computer program LFSC ( ) is a numerical tool for simulation beam based feedback in high performance linacs. The code LFSC is based on the earlier version developed by a collective of authors at SLAC (L.Hendrickson, R. McEwen, T. Himel, H. Shoaee, S. Shah, P. Emma, P. Schultz) during 1990-2005. That code was successively used in simulation of SLC, TESLA, CLIC and NLC projects. It can simulate as pulse-to-pulse feedback on timescale corresponding to 5-100 Hz, as slower feedbacks, operating in the 0.1-1 Hz range in the Main Linac and Beam Delivery System. The code LFSC is running under Matlab for MS Windows operating system. It contains about 30,000 lines of source code in more than 260 subroutines. The code uses the LIAR ('Linear Accelerator Research code') for particle tracking under ground motion and technical noise perturbations. It uses the Guinea Pig code to simulate the luminosity performance. A set of input files includes the lattice description (XSIF format), and plane text files with numerical parameters, wake fields, ground motion data etc. The Matlab environment provides a flexible system for graphical output

  6. Variable weight Khazani-Syed code using hybrid fixed-dynamic technique for optical code division multiple access system

    Science.gov (United States)

    Anas, Siti Barirah Ahmad; Seyedzadeh, Saleh; Mokhtar, Makhfudzah; Sahbudin, Ratna Kalos Zakiah

    2016-10-01

    Future Internet consists of a wide spectrum of applications with different bit rates and quality of service (QoS) requirements. Prioritizing the services is essential to ensure that the delivery of information is at its best. Existing technologies have demonstrated how service differentiation techniques can be implemented in optical networks using data link and network layer operations. However, a physical layer approach can further improve system performance at a prescribed received signal quality by applying control at the bit level. This paper proposes a coding algorithm to support optical domain service differentiation using spectral amplitude coding techniques within an optical code division multiple access (OCDMA) scenario. A particular user or service has a varying weight applied to obtain the desired signal quality. The properties of the new code are compared with other OCDMA codes proposed for service differentiation. In addition, a mathematical model is developed for performance evaluation of the proposed code using two different detection techniques, namely direct decoding and complementary subtraction.

  7. Simulation of experiment on aerosol behaviour at severe accident conditions in the LACE experimental facility with the ASTEC CPA code

    International Nuclear Information System (INIS)

    Kljenak, I.; Mavko, B.

    2007-01-01

    The experiment LACE LA4 on thermal-hydraulics and aerosol behavior in a nuclear power plant containment, which was performed in the LACE experimental facility, was simulated with the ASTEC CPA module of the severe accident computer code ASTEC V1.2. The specific purpose of the work was to assess the capability of the module (code) to simulate thermal-hydraulic conditions and aerosol behavior in the containment of a light-water-reactor nuclear power plant at severe accident conditions. The test was simulated with boundary conditions, described in the experiment report. Results of thermal-hydraulic conditions in the test vessel, as well as dry aerosol concentrations in the test vessel atmosphere, are compared to experimental results and analyzed. (author)

  8. A simplified treatment of the boundary conditions of the k- ε model in coarse-mesh CFD-type codes

    International Nuclear Information System (INIS)

    Analytis, G.Th.; Andreani, M.

    1999-01-01

    In coarse-mesh, CFD-type codes such as the containment analysis code GOTHIC, one of the options that can be used for modelling of turbulence is the k - ε model. However, in contrast to most other CFD codes which are designed to perform detailed CFD calculations with a large number of spatial meshes, codes such as GOTHIC are primarily aimed at simplified calculation of transients in large spaces (e.g., reactor containments), and generally use coarse meshes. The solution of the two parabolic equations for the k - ε model requires the definition of boundary conditions at physical boundaries and this, in turn, requires very small spatial meshes near these boundaries. Hence, while in codes like CFX this is done in a rigorous and consistent manner, codes like GOTHIC adopt an indirect and heuristic approach, due to the fact that the spatial meshes are usually large. This can have adverse consequences during the calculation of a transient and in this work, we shall give some examples of this and outline a method by which this problem can be avoided. (author)

  9. VALIDATION OF SIMBAT-PWR USING STANDARD CODE OF COBRA-EN ON REACTOR TRANSIENT CONDITION

    Directory of Open Access Journals (Sweden)

    Muhammad Darwis Isnaini

    2016-03-01

    Full Text Available The validation of Pressurized Water Reactor typed Nuclear Power Plant simulator developed by BATAN (SIMBAT-PWR using standard code of COBRA-EN on reactor transient condition has been done. The development of SIMBAT-PWR has accomplished several neutronics and thermal-hydraulic calculation modules. Therefore, the validation of the simulator is needed, especially in transient reactor operation condition. The research purpose is for characterizing the thermal-hydraulic parameters of PWR1000 core, which be able to be applied or as a comparison in developing the SIMBAT-PWR. The validation involves the calculation of the thermal-hydraulic parameters using COBRA-EN code. Furthermore, the calculation schemes are based on COBRA-EN with fixed material properties and dynamic properties that calculated by MATPRO subroutine (COBRA-EN+MATPRO for reactor condition of startup, power rise and power fluctuation from nominal to over power. The comparison of the temperature distribution at nominal 100% power shows that the fuel centerline temperature calculated by SIMBAT-PWR has 8.76% higher result than COBRA-EN result and 7.70% lower result than COBRA-EN+MATPRO. In general, SIMBAT-PWR calculation results on fuel temperature distribution are mostly between COBRA-EN and COBRA-EN+MATPRO results. The deviations of the fuel centerline, fuel surface, inner and outer cladding as well as coolant bulk temperature in the SIMBAT-PWR and the COBRA-EN calculation, are due to the value difference of the gap heat transfer coefficient and the cladding thermal conductivity.

  10. Bridging Inter-flow and Intra-flow Network Coding for Video Applications

    DEFF Research Database (Denmark)

    Hansen, Jonas; Krigslund, Jeppe; Roetter, Daniel Enrique Lucani

    2013-01-01

    transmission approach to decide how much and when to send redundancy in the network, and a minimalistic feedback mechanism to guarantee delivery of generations of the different flows. Given the delay constraints of video applications, we proposed a simple yet effective coding mechanism, Block Coding On The Fly...

  11. Network-Coded Content Delivery in Femtocaching-Assisted Cellular Networks

    KAUST Repository

    Shnaiwer, Yousef N.; Sorour, Sameh; Aboutorab, Neda; Sadeghi, Parastoo; Al-Naffouri, Tareq Y.

    2015-01-01

    Next-generation cellular networks are expected to be assisted by femtocaches (FCs), which collectively store the most popular files for the clients. Given any arbitrary non-fragmented placement of such files, a strict no-latency constraint, and clients' prior knowledge, new file download requests could be efficiently handled by both the FCs and the macrocell base station (MBS) using opportunistic network coding (ONC). In this paper, we aim to find the best allocation of coded file downloads to the FCs so as to minimize the MBS involvement in this download process. We first formulate this optimization problem over an ONC graph, and show that it is NP-hard. We then propose a greedy approach that maximizes the number of files downloaded by the FCs, with the goal to reduce the download share of the MBS. This allocation is performed using a dual conflict ONC graph to avoid conflicts among the FC downloads. Simulations show that our proposed scheme almost achieves the optimal performance and significantly saves on the MBS bandwidth.

  12. Network-Coded Content Delivery in Femtocaching-Assisted Cellular Networks

    KAUST Repository

    Shnaiwer, Yousef N.

    2015-12-06

    Next-generation cellular networks are expected to be assisted by femtocaches (FCs), which collectively store the most popular files for the clients. Given any arbitrary non-fragmented placement of such files, a strict no-latency constraint, and clients\\' prior knowledge, new file download requests could be efficiently handled by both the FCs and the macrocell base station (MBS) using opportunistic network coding (ONC). In this paper, we aim to find the best allocation of coded file downloads to the FCs so as to minimize the MBS involvement in this download process. We first formulate this optimization problem over an ONC graph, and show that it is NP-hard. We then propose a greedy approach that maximizes the number of files downloaded by the FCs, with the goal to reduce the download share of the MBS. This allocation is performed using a dual conflict ONC graph to avoid conflicts among the FC downloads. Simulations show that our proposed scheme almost achieves the optimal performance and significantly saves on the MBS bandwidth.

  13. RODSWELL: a computer code for the thermomechanical analysis of fuel rods under LOCA conditions

    International Nuclear Information System (INIS)

    Casadei, F.; Laval, H.; Donea, J.; Jones, P.M.; Colombo, A.

    1984-01-01

    The code calculates the variation in space and time of all significant fuel rod variables, including fuel, gap and cladding temperature, fuel and cladding deformation, cladding oxidation and rod internal pressure. The code combines a transient 2-dimensional heat conduction code and a 1-dimensional mechanical model for the cladding deformation. The first sections of this report deal with the heat conduction model and the finite element discretization used for the thermal analysis. The mechanical deformation model is presented next: modelling of creep, phase change and oxidation of the zircaloy cladding is discussed in detail. A model describing the effect of oxidation and oxide cracking on the mechanical strength of the cladding is presented too. Next a mechanical restraint model, which allows the simulation of the presence of the neighbouring rods and is particularly important in assessing the amount of channel blockage during a transient, is presented. A description of the models used for the coolant conditions and for the power generation follows. The heat source can be placed either in the fuel or in the cladding, and direct or indirect clad heating by electrical power can be simulated. Then a section follows, dealing with the steady-state and transient types of calculation and with the automatic variable time step selection during the transient. The last sections deal with presentation of results, graphical output, test problems and an example of general application of the code

  14. Coding Partitions

    Directory of Open Access Journals (Sweden)

    Fabio Burderi

    2007-05-01

    Full Text Available Motivated by the study of decipherability conditions for codes weaker than Unique Decipherability (UD, we introduce the notion of coding partition. Such a notion generalizes that of UD code and, for codes that are not UD, allows to recover the ``unique decipherability" at the level of the classes of the partition. By tacking into account the natural order between the partitions, we define the characteristic partition of a code X as the finest coding partition of X. This leads to introduce the canonical decomposition of a code in at most one unambiguouscomponent and other (if any totally ambiguouscomponents. In the case the code is finite, we give an algorithm for computing its canonical partition. This, in particular, allows to decide whether a given partition of a finite code X is a coding partition. This last problem is then approached in the case the code is a rational set. We prove its decidability under the hypothesis that the partition contains a finite number of classes and each class is a rational set. Moreover we conjecture that the canonical partition satisfies such a hypothesis. Finally we consider also some relationships between coding partitions and varieties of codes.

  15. Fission Product Transport Models Adopted in REFPAC Code for LOCA Conditions in PWR and WWER NPPS

    International Nuclear Information System (INIS)

    Strupczewski, A.

    2003-01-01

    The report presents assumptions and physical models used for calculations of fission product releases from nuclear reactors, their behavior inside the containment and leakages to the environment after large break loss of coolant accident LB LOCA. They are the basis of code REFPAC (RElease of Fission Products under Accident Conditions), designed primarily to represent significant physical processes occurring after LB LOCA. The code describes these processes using three different models. Model 1 corresponds to established US and Russian practice, Model 2 includes all conservative assumptions that are in agreement with the actual state-of-the-art, and Model 3 incorporates formulae and parameter values actually used in EU practice. (author)

  16. Highly stable and degradable multifunctional microgel for self-regulated insulin delivery under physiological conditions

    Science.gov (United States)

    Zhang, Xinjie; Lü, Shaoyu; Gao, Chunmei; Chen, Chen; Zhang, Xuan; Liu, Mingzhu

    2013-06-01

    The response to glucose, pH and temperature, high drug loading capacity, self-regulated drug delivery and degradation in vivo are simultaneously probable by applying a multifunctional microgel under a rational design in a colloid chemistry method. Such multifunctional microgels are fabricated with N-isopropylacrylamide (NIPAAm), (2-dimethylamino)ethyl methacrylate (DMAEMA) and 3-acrylamidephenylboronic acid (AAPBA) through a precipitation emulsion method and cross-linked by reductive degradable N,N'-bis(arcyloyl)cystamine (BAC). This novel kind of microgel with a narrow size distribution (~250 nm) is suitable for diabetes because it can adapt to the surrounding medium of different glucose concentrations over a clinically relevant range (0-20 mM), control the release of preloaded insulin and is highly stable under physiological conditions (pH 7.4, 0.15 M NaCl, 37 °C). When synthesized multifunctional microgels regulate drug delivery, they gradually degrade as time passes and, as a result, show enhanced biocompatibility. This exhibits a new proof-of-concept for diabetes treatment that takes advantage of the properties of each building block from a multifunctional micro-object. These highly stable and versatile multifunctional microgels have the potential to be used for self-regulated therapy and monitoring of the response to treatment, or even simultaneous diagnosis as nanobiosensors.The response to glucose, pH and temperature, high drug loading capacity, self-regulated drug delivery and degradation in vivo are simultaneously probable by applying a multifunctional microgel under a rational design in a colloid chemistry method. Such multifunctional microgels are fabricated with N-isopropylacrylamide (NIPAAm), (2-dimethylamino)ethyl methacrylate (DMAEMA) and 3-acrylamidephenylboronic acid (AAPBA) through a precipitation emulsion method and cross-linked by reductive degradable N,N'-bis(arcyloyl)cystamine (BAC). This novel kind of microgel with a narrow size

  17. Software Build and Delivery Systems

    Energy Technology Data Exchange (ETDEWEB)

    Robey, Robert W. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-07-10

    This presentation deals with the hierarchy of software build and delivery systems. One of the goals is to maximize the success rate of new users and developers when first trying your software. First impressions are important. Early successes are important. This also reduces critical documentation costs. This is a presentation focused on computer science and goes into detail about code documentation.

  18. RAP-3A Computer code for thermal and hydraulic calculations in steady state conditions for fuel element clusters

    International Nuclear Information System (INIS)

    Popescu, C.; Biro, L.; Iftode, I.; Turcu, I.

    1975-10-01

    The RAP-3A computer code is designed for calculating the main steady state thermo-hydraulic parameters of multirod fuel clusters with liquid metal cooling. The programme provides a double accuracy computation of temperatures and axial enthalpy distributions of pressure losses and axial heat flux distributions in fuel clusters before boiling conditions occur. Physical and mathematical models as well as a sample problem are presented. The code is written in FORTRAN-4 language and is running on a IBM-370/135 computer

  19. Induction of transplantation tolerance by combining non-myeloablative conditioning with delivery of alloantigen by T cells

    Science.gov (United States)

    Tian, Chaorui; Yuan, Xueli; Bagley, Jessamyn; Blazar, Bruce R.; Sayegh, Mohamed H.; Iacomini, John

    2008-01-01

    The observation that bone marrow derived hematopoietic cells are potent inducers of tolerance has generated interest in trying to establish transplantation tolerance by inducing a state of hematopoietic chimerism through allogeneic bone marrow transplantation. However, this approach is associated with serious complications that limit its utility for tolerance induction. Here we describe the development of a novel approach that allows for tolerance induction without the need for an allogeneic bone marrow transplant by combining non-myeloablative host conditioning with delivery of donor alloantigen by adoptively transferred T cells. CBA/Ca mice were administered 2.5Gy whole body irradiation (WBI). The following day the mice received Kb disparate T cells from MHC class I transgenic CBK donor mice, as well as rapamycin on days 0–13 and anti-CD40L monoclonal antibody on days 0–5, 8,11 and 14 relative to T cell transfer. Mice treated using this approach were rendered specifically tolerant to CBK skin allografts through a mechanism involving central and peripheral deletion of alloreactive T cells. These data suggest robust tolerance can be established without the need for bone marrow transplantation using clinically relevant non-myeloablative conditioning combined with antigen delivery by T cells. PMID:18280792

  20. Anesthetic and Obstetric Management of Syringomyelia During Labor and Delivery: A Case Series and Systematic Review.

    Science.gov (United States)

    Garvey, Gráinne Patricia; Wasade, Vibhangini S; Murphy, Kellie E; Balki, Mrinalini

    2017-09-01

    Syringomyelia is a rare, slowly progressive neurological condition characterized by the presence of a syrinx within the spinal cord. Consensus regarding the safest mode of delivery and anesthetic management in patients with syringomyelia remains controversial and presents management dilemmas. This study reviews the cases of syringomyelia at our institution and provides a systematic review of the literature to guide decisions regarding labor and delivery management. A retrospective review of cases at our hospital from 2002 to 2014 and a systematic review of the literature from 1946 to 2014 were undertaken. Hospital records and electronic databases were interrogated using International Classification of Diseases, 10th Revision codes and the keywords "syringomyelia," "syringobulbia," and "pregnancy." Data regarding demographics, diagnosis, radiology reports, neurological symptoms, mode of delivery, anesthetic management, and maternal-fetal outcomes were collected. We collected and analyzed data on a total of 43 pregnancies in 39 patients. The most common location for syrinx was in the cervicothoracic region (41.9%). The large majority of patients (n = 34; 87%) demonstrated signs and symptoms associated with syringomyelia before delivery. Syringomyelia associated with Arnold Chiari malformation was documented in 49% (n = 21) cases. General anesthesia was the most commonly used (n = 21/30, 70%) anesthetic technique for cesarean delivery. The majority (n = 9/13, 69%) of patients had an epidural sited for labor analgesia. There were no maternal or neonatal complications associated with neuraxial anesthesia; however, 3 cases (14%) raised concerns regarding general anesthesia including difficult intubation, transient worsening of neurological symptoms postpartum, and prolonged muscle paralysis after atracurium. Despite concerns regarding aggravation of the syrinx with vaginal delivery, this mode of delivery has never caused any documented long-term worsening of neurological

  1. Simulation of KAEVER experiments on aerosol behavior in a nuclear power plant containment at accident conditions with the ASTEC code

    International Nuclear Information System (INIS)

    Kljenak, I.; Mavko, B.

    2006-01-01

    Experiments on aerosol behaviour in saturated and non-saturated atmosphere, which were performed in the KAEVER experimental facility, were simulated with the severe accident computer code ASTEC CPA V1.2. The specific purpose of the work was to assess the capability of the code to model aerosol condensation and deposition in the containment of a light-water-reactor nuclear power plant at severe accident conditions, if the atmosphere saturation conditions are simulated adequately. Five different tests were first simulated with boundary conditions, obtained from the experiments. In all five tests, a non-saturated atmosphere was simulated, although, in four tests, the atmosphere was allegedly saturated. The simulations were repeated with modified boundary conditions, to obtain a saturated atmosphere in all tests. Results of dry and wet aerosol concentrations in the test vessel atmosphere for both sets of simulations are compared to experimental results. (author)

  2. Delivery of therapeutics for deep-seated ocular conditions - status quo.

    Science.gov (United States)

    Nguyen, Hubert; Eng, Shawn; Ngo, Thanh; Dass, Crispin R

    2018-04-19

    There is a need for research into designing effective pharmaceutical systems for delivering therapeutic drugs to the posterior of the eye for glaucoma-related pathology, macular degeneration, diabetic retinopathy, macular oedema, retinitis and choroiditis. Conventionally, eye drops have been extensively utilised for topical drug delivery to the anterior segment of the eye, but are less effective for delivery of therapeutics to the back of the eye due to significant barriers hampering drug penetration into the target intraocular tissue. This review explores some of the current and novel delivery systems employed to deliver therapeutics to the back of the eye such as those using liposomes, ocular implants, in situ gels, and nanoparticles, and how they can overcome some of these limitations. Issues such as blinking, precorneal fluid drainage, tear dilution and turnover, conjunctiva and nasal drug absorption, the corneal epithelium, vitreous drug clearance, and the blood-ocular barriers are reviewed and discussed. Further studies are needed to address their shortcomings such as drug compatibility and stability, economic viability and patient compliance. © 2018 Royal Pharmaceutical Society.

  3. Communication Between Devices in the Viola Document Delivery System

    Directory of Open Access Journals (Sweden)

    Theodor Tolstoy

    2015-01-01

    Full Text Available Viola is a newly developed document delivery system that handles incoming and outgoing requests for printed books, articles, sharing electronic resources, and other document delivery services on the local level in a library organisation. An important part of Viola is the stack fetching Android application that enables librarians to collect books in the open and closed stacks in an efficient manner using a smartphone and a Bluetooth connected portable printer. The aim of this article is to show how information is transferred between systems and devices in Viola. The article presents code examples from Viola that use current .NET technologies. The examples span from the creation of high-level REST-based JSON APIs to byte array communication with a Bluetooth connected printer and the reading of RFID tags. Please note that code examples in this article are for illustration purposes only. Null checking and other exception handling has been removed for clarity. Code that is separated in Viola for testability and other reasons has been brought together to make it more readable.

  4. Estimation of reactor core calculation by HELIOS/MASTER at power generating condition through DeCART, whole-core transport code

    International Nuclear Information System (INIS)

    Kim, H. Y.; Joo, H. G.; Kim, K. S.; Kim, G. Y.; Jang, M. H.

    2003-01-01

    The reactivity and power distribution errors of the HELIOS/MASTER core calculation under power generating conditions are assessed using a whole core transport code DeCART. For this work, the cross section tablesets were generated for a medium sized PWR following the standard procedure and two group nodal core calculations were performed. The test cases include the HELIOS calculations for 2-D assemblies at constant thermal conditions, MASTER 3D assembly calculations at power generating conditions, and the core calculations at HZP, HFP, and an abnormal power conditions. In all these cases, the results of the DeCART code in which pinwise thermal feedback effects are incorporated are used as the reference. The core reactivity, assemblywise power distribution, axial power distribution, peaking factor, and thermal feedback effects are then compared. The comparison shows that the error of the HELIOS/MASTER system in the core reactivity, assembly wise power distribution, pin peaking factor are only 100∼300 pcm, 3%, and 2%, respectively. As far as the detailed pinwise power distribution is concerned, however, errors greater than 15% are observed

  5. Improved inter-assembly heat transfer modeling under low flow conditions for the Super System Code (SSC)

    International Nuclear Information System (INIS)

    Horak, W.C.; Guppy, J.G.

    1984-01-01

    The Super System Code (SSC) was developed at the Brookhaven National Laboratory (BNL) for the thermal hydraulic analysis of natural circulation transients, operational transients, and other system wide transients in nuclear power plants. SSC is a generic, best estimate code that models the in-vessel components, heat transport loops, plant protection systems and plant control systems. SSC also simulates the balance of plant when interfaced with the MINET code. SSC has been validated against both numerical and experimental data bases and is now used by several outside users. An important area of interest in LMFBR transient analysis is the prediction of the response of the reactor core under low flow conditions, such as experienced during a natural circulation event. Under these circumstances there are many physical phenomena which must be modeled to provide an adequate representation by a computer code simulation. The present version of SSC contains numerous models which account for most of the major phenomena. However, one area where the present model in SSC is being improved is in the representation of heat transfer and buoyancy effects under low flow operation. To properly improve the present version, the addition of models to represent certain inter-assembly effects is required

  6. The effect of code user and boundary conditions on RELAP calculations of MTR research reactor transient scenarios

    Directory of Open Access Journals (Sweden)

    Khedr Ahmed

    2005-01-01

    Full Text Available The safety evaluation of nuclear power and re search reactors is a very important step before their construction and during their operation. This evaluation based on the best estimate calculations requires qualified codes qualified users, and qualified nodalizations. The effect of code users on the RELAP5 results during the analysis of loss of flow transient in MTR research reactors is presented in this pa per. To clarify this effect, two nodalizations for research reactor different in the simulation of the open water surface boundary conditions of the reactor pool have been used. Very different results are obtained with few choices for code users. The core natural circulation flow with the be ginning of core boiling doesn't stop but in creases. The in creasing in the natural circulation flow shifts out the boiling from the core and the clad temperature decreases be low the local saturation temperature.

  7. CODE-RADE - Community Infrastructure for the Delivery of Physics Applications

    OpenAIRE

    Becker, Bruce; Murray, Sean

    2017-01-01

    Scientific computing can in some sense be distilled to the execution of an application - or rather sets of applications which are combined into complex workflows. Due to the complexity and number both of scientific packages as well as computing platforms, delivering these applications to end users has always been a significant challenge through the grid era, and remains so in the cloud era. In this contribution we describe a platform for user-driven, continuous integration and delivery of res...

  8. Quantum Codes From Cyclic Codes Over The Ring R 2

    International Nuclear Information System (INIS)

    Altinel, Alev; Güzeltepe, Murat

    2016-01-01

    Let R 2 denotes the ring F 2 + μF 2 + υ 2 + μυ F 2 + wF 2 + μwF 2 + υwF 2 + μυwF 2 . In this study, we construct quantum codes from cyclic codes over the ring R 2 , for arbitrary length n, with the restrictions μ 2 = 0, υ 2 = 0, w 2 = 0, μυ = υμ, μw = wμ, υw = wυ and μ (υw) = (μυ) w. Also, we give a necessary and sufficient condition for cyclic codes over R 2 that contains its dual. As a final point, we obtain the parameters of quantum error-correcting codes from cyclic codes over R 2 and we give an example of quantum error-correcting codes form cyclic codes over R 2 . (paper)

  9. Multiple component codes based generalized LDPC codes for high-speed optical transport.

    Science.gov (United States)

    Djordjevic, Ivan B; Wang, Ting

    2014-07-14

    A class of generalized low-density parity-check (GLDPC) codes suitable for optical communications is proposed, which consists of multiple local codes. It is shown that Hamming, BCH, and Reed-Muller codes can be used as local codes, and that the maximum a posteriori probability (MAP) decoding of these local codes by Ashikhmin-Lytsin algorithm is feasible in terms of complexity and performance. We demonstrate that record coding gains can be obtained from properly designed GLDPC codes, derived from multiple component codes. We then show that several recently proposed classes of LDPC codes such as convolutional and spatially-coupled codes can be described using the concept of GLDPC coding, which indicates that the GLDPC coding can be used as a unified platform for advanced FEC enabling ultra-high speed optical transport. The proposed class of GLDPC codes is also suitable for code-rate adaption, to adjust the error correction strength depending on the optical channel conditions.

  10. Source Code Analysis Laboratory (SCALe) for Energy Delivery Systems

    Science.gov (United States)

    2010-12-01

    technical competence for the type of tests and calibrations SCALe undertakes. Testing and calibration laboratories that comply with ISO / IEC 17025 ...and exec t [ ISO / IEC 2005]. f a software system indicates that the SCALe analysis di by a CERT secure coding standard. Successful conforma antees that...to be more secure than non- systems. However, no study has yet been performed to p t ssment in accordance with ISO / IEC 17000: “a demonstr g to a

  11. New quantum codes derived from a family of antiprimitive BCH codes

    Science.gov (United States)

    Liu, Yang; Li, Ruihu; Lü, Liangdong; Guo, Luobin

    The Bose-Chaudhuri-Hocquenghem (BCH) codes have been studied for more than 57 years and have found wide application in classical communication system and quantum information theory. In this paper, we study the construction of quantum codes from a family of q2-ary BCH codes with length n=q2m+1 (also called antiprimitive BCH codes in the literature), where q≥4 is a power of 2 and m≥2. By a detailed analysis of some useful properties about q2-ary cyclotomic cosets modulo n, Hermitian dual-containing conditions for a family of non-narrow-sense antiprimitive BCH codes are presented, which are similar to those of q2-ary primitive BCH codes. Consequently, via Hermitian Construction, a family of new quantum codes can be derived from these dual-containing BCH codes. Some of these new antiprimitive quantum BCH codes are comparable with those derived from primitive BCH codes.

  12. Analysis of Non-binary Hybrid LDPC Codes

    OpenAIRE

    Sassatelli, Lucile; Declercq, David

    2008-01-01

    In this paper, we analyse asymptotically a new class of LDPC codes called Non-binary Hybrid LDPC codes, which has been recently introduced. We use density evolution techniques to derive a stability condition for hybrid LDPC codes, and prove their threshold behavior. We study this stability condition to conclude on asymptotic advantages of hybrid LDPC codes compared to their non-hybrid counterparts.

  13. Input/output manual of light water reactor fuel performance code FEMAXI-7 and its related codes

    Energy Technology Data Exchange (ETDEWEB)

    Suzuki, Motoe; Udagawa, Yutaka; Nagase, Fumihisa [Japan Atomic Energy Agency, Nuclear Safety Research Center, Tokai, Ibaraki (Japan); Saitou, Hiroaki [ITOCHU Techno-Solutions Corp., Tokyo (Japan)

    2012-07-15

    A light water reactor fuel analysis code FEMAXI-7 has been developed for the purpose of analyzing the fuel behavior in normal conditions and in anticipated transient conditions. Numerous functional improvements and extensions have been incorporated in FEMAXI-7, which has been fully disclosed in the code model description published recently as JAEA-Data/Code 2010-035. The present manual, which is the counterpart of this description, gives detailed explanations of operation method of FEMAXI-7 code and its related codes, methods of Input/Output, methods of source code modification, features of subroutine modules, and internal variables in a specific manner in order to facilitate users to perform a fuel analysis with FEMAXI-7. This report includes some descriptions which are modified from the original contents of JAEA-Data/Code 2010-035. A CD-ROM is attached as an appendix. (author)

  14. Input/output manual of light water reactor fuel performance code FEMAXI-7 and its related codes

    International Nuclear Information System (INIS)

    Suzuki, Motoe; Udagawa, Yutaka; Nagase, Fumihisa; Saitou, Hiroaki

    2012-07-01

    A light water reactor fuel analysis code FEMAXI-7 has been developed for the purpose of analyzing the fuel behavior in normal conditions and in anticipated transient conditions. Numerous functional improvements and extensions have been incorporated in FEMAXI-7, which has been fully disclosed in the code model description published recently as JAEA-Data/Code 2010-035. The present manual, which is the counterpart of this description, gives detailed explanations of operation method of FEMAXI-7 code and its related codes, methods of Input/Output, methods of source code modification, features of subroutine modules, and internal variables in a specific manner in order to facilitate users to perform a fuel analysis with FEMAXI-7. This report includes some descriptions which are modified from the original contents of JAEA-Data/Code 2010-035. A CD-ROM is attached as an appendix. (author)

  15. Coding Labour

    Directory of Open Access Journals (Sweden)

    Anthony McCosker

    2014-03-01

    Full Text Available As well as introducing the Coding Labour section, the authors explore the diffusion of code across the material contexts of everyday life, through the objects and tools of mediation, the systems and practices of cultural production and organisational management, and in the material conditions of labour. Taking code beyond computation and software, their specific focus is on the increasingly familiar connections between code and labour with a focus on the codification and modulation of affect through technologies and practices of management within the contemporary work organisation. In the grey literature of spreadsheets, minutes, workload models, email and the like they identify a violence of forms through which workplace affect, in its constant flux of crisis and ‘prodromal’ modes, is regulated and governed.

  16. The Aster code; Code Aster

    Energy Technology Data Exchange (ETDEWEB)

    Delbecq, J.M

    1999-07-01

    The Aster code is a 2D or 3D finite-element calculation code for structures developed by the R and D direction of Electricite de France (EdF). This dossier presents a complete overview of the characteristics and uses of the Aster code: introduction of version 4; the context of Aster (organisation of the code development, versions, systems and interfaces, development tools, quality assurance, independent validation); static mechanics (linear thermo-elasticity, Euler buckling, cables, Zarka-Casier method); non-linear mechanics (materials behaviour, big deformations, specific loads, unloading and loss of load proportionality indicators, global algorithm, contact and friction); rupture mechanics (G energy restitution level, restitution level in thermo-elasto-plasticity, 3D local energy restitution level, KI and KII stress intensity factors, calculation of limit loads for structures), specific treatments (fatigue, rupture, wear, error estimation); meshes and models (mesh generation, modeling, loads and boundary conditions, links between different modeling processes, resolution of linear systems, display of results etc..); vibration mechanics (modal and harmonic analysis, dynamics with shocks, direct transient dynamics, seismic analysis and aleatory dynamics, non-linear dynamics, dynamical sub-structuring); fluid-structure interactions (internal acoustics, mass, rigidity and damping); linear and non-linear thermal analysis; steels and metal industry (structure transformations); coupled problems (internal chaining, internal thermo-hydro-mechanical coupling, chaining with other codes); products and services. (J.S.)

  17. Input/output manual of light water reactor fuel analysis code FEMAXI-7 and its related codes

    Energy Technology Data Exchange (ETDEWEB)

    Suzuki, Motoe; Udagawa, Yutaka; Nagase, Fumihisa [Japan Atomic Energy Agency, Nuclear Safety Research Center, Tokai, Ibaraki (Japan); Saitou, Hiroaki [ITOCHU Techno-Solutions Corporation, Tokyo (Japan)

    2013-10-15

    A light water reactor fuel analysis code FEMAXI-7 has been developed, as an extended version from the former version FEMAXI-6, for the purpose of analyzing the fuel behavior in normal conditions and in anticipated transient conditions. Numerous functional improvements and extensions have been incorporated in FEMAXI-7, which are fully disclosed in the code model description published in the form of another JAEA-Data/Code report. The present manual, which is the very counterpart of this description document, gives detailed explanations of files and operation method of FEMAXI-7 code and its related codes, methods of input/output, sample Input/Output, methods of source code modification, subroutine structure, and internal variables in a specific manner in order to facilitate users to perform fuel analysis by FEMAXI-7. (author)

  18. Input/output manual of light water reactor fuel analysis code FEMAXI-7 and its related codes

    International Nuclear Information System (INIS)

    Suzuki, Motoe; Udagawa, Yutaka; Nagase, Fumihisa; Saitou, Hiroaki

    2013-10-01

    A light water reactor fuel analysis code FEMAXI-7 has been developed, as an extended version from the former version FEMAXI-6, for the purpose of analyzing the fuel behavior in normal conditions and in anticipated transient conditions. Numerous functional improvements and extensions have been incorporated in FEMAXI-7, which are fully disclosed in the code model description published in the form of another JAEA-Data/Code report. The present manual, which is the very counterpart of this description document, gives detailed explanations of files and operation method of FEMAXI-7 code and its related codes, methods of input/output, sample Input/Output, methods of source code modification, subroutine structure, and internal variables in a specific manner in order to facilitate users to perform fuel analysis by FEMAXI-7. (author)

  19. Polarization diversity scheme on spectral polarization coding optical code-division multiple-access network

    Science.gov (United States)

    Yen, Chih-Ta; Huang, Jen-Fa; Chang, Yao-Tang; Chen, Bo-Hau

    2010-12-01

    We present an experiment demonstrating the spectral-polarization coding optical code-division multiple-access system introduced with a nonideal state of polarization (SOP) matching conditions. In the proposed system, the encoding and double balanced-detection processes are implemented using a polarization-diversity scheme. Because of the quasiorthogonality of Hadamard codes combining with array waveguide grating routers and a polarization beam splitter, the proposed codec pair can encode-decode multiple code words of Hadamard code while retaining the ability for multiple-access interference cancellation. The experimental results demonstrate that when the system is maintained with an orthogonal SOP for each user, an effective reduction in the phase-induced intensity noise is obtained. The analytical SNR values are found to overstate the experimental results by around 2 dB when the received effective power is large. This is mainly limited by insertion losses of components and a nonflattened optical light source. Furthermore, the matching conditions can be improved by decreasing nonideal influences.

  20. HVAC-DYNAMICS - a tool for quality assurance in relation to delivery of air-conditioning systems. [Heating, ventilating and air conditioning]. HVAC-DYNAMICS - et redskap for kvalitetsikring av sluttleveransen i klima-anlegg

    Energy Technology Data Exchange (ETDEWEB)

    Novakovic, V [SINTEF Varmeteknikk, Seksjon VVS (NO)

    1990-07-01

    HVAC-DYNAMICS is a computerized tool for quality assurance of the functioning of an air-conditioning system at the time of delivery. The system's efficiency in the case of fluctuating and critical operation is evaluated. The HVAC-DYNAMICS gives an optimal choice for air-conditioning systems regarding indoor climate, efficiency demands and energy consumption. The program can also be use for calibration of regulators, fault-finding, and training purposes. (CLS).

  1. BEAVRS full core burnup calculation in hot full power condition by RMC code

    International Nuclear Information System (INIS)

    Liu, Shichang; Liang, Jingang; Wu, Qu; Guo, JuanJuan; Huang, Shanfang; Tang, Xiao; Li, Zeguang; Wang, Kan

    2017-01-01

    Highlights: • TMS and thermal scattering interpolation were developed to treat cross sections OTF. • Hybrid coupling system was developed for HFP burnup calculation of BEAVRS benchmark. • Domain decomposition was applied to handle memory problem of full core burnup. • Critical boron concentration with burnup by RMC agrees with the benchmark results. • RMC is capable of multi-physics coupling for simulations of nuclear reactors in HFP. - Abstract: Monte Carlo method can provide high fidelity neutronics analysis of different types of nuclear reactors, owing to its advantages of the flexible geometry modeling and the use of continuous-energy nuclear cross sections. However, nuclear reactors are complex systems with multi-physics interacting and coupling. MC codes can couple with depletion solver and thermal-hydraulics (T/H) codes simultaneously for the “transport-burnup-thermal-hydraulics” coupling calculations. MIT BEAVRS is a typical “transport-burnup-thermal-hydraulics” coupling benchmark. In this paper, RMC was coupled with sub-channel code COBRA, equipped with on-the-fly temperature-dependent cross section treatment and large-scale detailed burnup calculation based on domain decomposition. Then RMC was applied to the full core burnup calculations of BEAVRS benchmark in hot full power (HFP) condition. The numerical tests show that domain decomposition method can achieve the consistent results compared with original version of RMC while enlarging the computational burnup regions. The results of HFP by RMC agree well with the reference values of BEAVRS benchmark and also agree well with those of MC21. This work proves the feasibility and accuracy of RMC in multi-physics coupling and lifecycle simulations of nuclear reactors.

  2. Bar-code automated waste tracking system

    International Nuclear Information System (INIS)

    Hull, T.E.

    1994-10-01

    The Bar-Code Automated Waste Tracking System was designed to be a site-Specific program with a general purpose application for transportability to other facilities. The system is user-friendly, totally automated, and incorporates the use of a drive-up window that is close to the areas dealing in container preparation, delivery, pickup, and disposal. The system features ''stop-and-go'' operation rather than a long, tedious, error-prone manual entry. The system is designed for automation but allows operators to concentrate on proper handling of waste while maintaining manual entry of data as a backup. A large wall plaque filled with bar-code labels is used to input specific details about any movement of waste

  3. Calculation of local flow conditions in the lower core of a PWR with code-Saturne

    International Nuclear Information System (INIS)

    Fournier, Y.

    2003-01-01

    In order to better understand the stresses to which fuel rods are subjected, we need to improve our knowledge of the fluid flow inside the core. A code specialized for calculations in tube bundles is used to calculate the flow inside the whole of the core, with a resolution at the assembly level. Still, it is necessary to obtain realistic entry conditions, and these depend on the flow in the downcomer and lower plenum. Also, the flow in the first stages of the core features 4 incoming jets per assembly, and requires a resolution much finer than that used for the whole core calculation. A series of calculations are thus run with our incompressible Navier-Stokes solver, Code-Saturne, using a classical Ranse turbulence model. The first calculations involve a detailed geometry, including part of the cold legs, downcomer, lower plenum, and lower core of a pressurized water reactor. The level of detail includes most obstacles below the core. The lower core plate, being pierced with close to 800 holes, cannot be realistically represented within a practical mesh size, so that a head loss model is used. The lower core itself requiring even more detail is also represented with head losses. We make full use of Code-Saturne's non conforming mesh possibilities to represent a complex geometry, being careful to retain a good mesh quality. Starting just under the lower core, the mesh is aligned with fuel rod assemblies, so that different types of assemblies can be represented through different head loss coefficients. These calculations yield steady-state or near steady-state results, which are compared to experimental data, and should be sufficient to yield realistic entry conditions for full core calculations at assembly width resolution, and beyond those mechanical strain calculations. We are also interested in more detailed flow conditions and fluctuations in the lower core area, so as to better quantify vibrational input. This requires a much higher resolution, which we limit

  4. Adjustment of the thermohydraulic NUCIRC 2.0 code to the present aging conditions of the Embalse nuclear power plant

    International Nuclear Information System (INIS)

    Rabiti, Arnaldo; Coutsiers, Ernesto; Schivo, Miguel; Mazanttini, Oscar

    2003-01-01

    This work gives a description of the adjustment process of NUCIRC code to the actual aging conditions of Embalse nuclear power plant. For this adjustment the flow of the fuel channels of the primary heat transport system (PHTS) is calculated using the channel heat balance flow (CHBF) methodology. Then roughness and the localized loss of charge are modified in NUCIRC code for different groups of channels. These adjustments are done in way to fit by regions the channels flows calculated with NUCIRC to the CHBF flows. The fitting results in a discrepancy by regions of less than 0,1% and an average quadratic error of 5% approximately. These values indicate that the code NUCIRC is right adjusted for critical channel power calculations and aging tracking of PHTS. (author)

  5. Preliminary Coupling of MATRA Code for Multi-physics Analysis

    International Nuclear Information System (INIS)

    Kim, Seongjin; Choi, Jinyoung; Yang, Yongsik; Kwon, Hyouk; Hwang, Daehyun

    2014-01-01

    The boundary conditions such as the inlet temperature, mass flux, averaged heat flux, power distributions of the rods, and core geometry is given by constant values or functions of time. These conditions are separately calculated and provided by other codes, such as a neutronics or a system codes, into the MATRA code. In addition, the coupling of several codes in the different physics field is focused and embodied. In this study, multiphysics coupling methods were developed for a subchannel code (MATRA) with neutronics codes (MASTER, DeCART) and a fuel performance code (FRAPCON-3). Preliminary evaluation results for representative sample cases are presented. The MASTER and DeCART codes provide the power distribution of the rods in the core to the MATRA code. In case of the FRAPCON-3 code, the variation of the rod diameter induced by the thermal expansion is yielded and provided. The MATRA code transfers the thermal-hydraulic conditions that each code needs. Moreover, the coupling method with each code is described

  6. Verification of reactor safety codes

    International Nuclear Information System (INIS)

    Murley, T.E.

    1978-01-01

    The safety evaluation of nuclear power plants requires the investigation of wide range of potential accidents that could be postulated to occur. Many of these accidents deal with phenomena that are outside the range of normal engineering experience. Because of the expense and difficulty of full scale tests covering the complete range of accident conditions, it is necessary to rely on complex computer codes to assess these accidents. The central role that computer codes play in safety analyses requires that the codes be verified, or tested, by comparing the code predictions with a wide range of experimental data chosen to span the physical phenomena expected under potential accident conditions. This paper discusses the plans of the Nuclear Regulatory Commission for verifying the reactor safety codes being developed by NRC to assess the safety of light water reactors and fast breeder reactors. (author)

  7. Dynamic benchmarking of simulation codes

    International Nuclear Information System (INIS)

    Henry, R.E.; Paik, C.Y.; Hauser, G.M.

    1996-01-01

    Computer simulation of nuclear power plant response can be a full-scope control room simulator, an engineering simulator to represent the general behavior of the plant under normal and abnormal conditions, or the modeling of the plant response to conditions that would eventually lead to core damage. In any of these, the underlying foundation for their use in analysing situations, training of vendor/utility personnel, etc. is how well they represent what has been known from industrial experience, large integral experiments and separate effects tests. Typically, simulation codes are benchmarked with some of these; the level of agreement necessary being dependent upon the ultimate use of the simulation tool. However, these analytical models are computer codes, and as a result, the capabilities are continually enhanced, errors are corrected, new situations are imposed on the code that are outside of the original design basis, etc. Consequently, there is a continual need to assure that the benchmarks with important transients are preserved as the computer code evolves. Retention of this benchmarking capability is essential to develop trust in the computer code. Given the evolving world of computer codes, how is this retention of benchmarking capabilities accomplished? For the MAAP4 codes this capability is accomplished through a 'dynamic benchmarking' feature embedded in the source code. In particular, a set of dynamic benchmarks are included in the source code and these are exercised every time the archive codes are upgraded and distributed to the MAAP users. Three different types of dynamic benchmarks are used: plant transients; large integral experiments; and separate effects tests. Each of these is performed in a different manner. The first is accomplished by developing a parameter file for the plant modeled and an input deck to describe the sequence; i.e. the entire MAAP4 code is exercised. The pertinent plant data is included in the source code and the computer

  8. Discriminative sparse coding on multi-manifolds

    KAUST Repository

    Wang, J.J.-Y.; Bensmail, H.; Yao, N.; Gao, Xin

    2013-01-01

    Sparse coding has been popularly used as an effective data representation method in various applications, such as computer vision, medical imaging and bioinformatics. However, the conventional sparse coding algorithms and their manifold-regularized variants (graph sparse coding and Laplacian sparse coding), learn codebooks and codes in an unsupervised manner and neglect class information that is available in the training set. To address this problem, we propose a novel discriminative sparse coding method based on multi-manifolds, that learns discriminative class-conditioned codebooks and sparse codes from both data feature spaces and class labels. First, the entire training set is partitioned into multiple manifolds according to the class labels. Then, we formulate the sparse coding as a manifold-manifold matching problem and learn class-conditioned codebooks and codes to maximize the manifold margins of different classes. Lastly, we present a data sample-manifold matching-based strategy to classify the unlabeled data samples. Experimental results on somatic mutations identification and breast tumor classification based on ultrasonic images demonstrate the efficacy of the proposed data representation and classification approach. 2013 The Authors. All rights reserved.

  9. Discriminative sparse coding on multi-manifolds

    KAUST Repository

    Wang, J.J.-Y.

    2013-09-26

    Sparse coding has been popularly used as an effective data representation method in various applications, such as computer vision, medical imaging and bioinformatics. However, the conventional sparse coding algorithms and their manifold-regularized variants (graph sparse coding and Laplacian sparse coding), learn codebooks and codes in an unsupervised manner and neglect class information that is available in the training set. To address this problem, we propose a novel discriminative sparse coding method based on multi-manifolds, that learns discriminative class-conditioned codebooks and sparse codes from both data feature spaces and class labels. First, the entire training set is partitioned into multiple manifolds according to the class labels. Then, we formulate the sparse coding as a manifold-manifold matching problem and learn class-conditioned codebooks and codes to maximize the manifold margins of different classes. Lastly, we present a data sample-manifold matching-based strategy to classify the unlabeled data samples. Experimental results on somatic mutations identification and breast tumor classification based on ultrasonic images demonstrate the efficacy of the proposed data representation and classification approach. 2013 The Authors. All rights reserved.

  10. PC-version of RAM6-code for calculation of parameters of the effective logarithmic boundary condition at the absorbent rod surface in reactor

    International Nuclear Information System (INIS)

    Le Van Ngoc; Ngo Dang Nhan

    1990-01-01

    The RAM-6 code for calculation of parameters of the effective logarithmic boundary condition at the absorbent rod surface in reactor is suitably modofied to work on IBM PC, the instructions for its usage are presented and capabilities of the personal cpmputer oriented RAM-6 code are demonstrated. (author). 4 refs, 5 tabs, 2 figs

  11. Verification of Dinamika-5 code on experimental data of water level behaviour in PGV-440 under dynamic conditions

    Energy Technology Data Exchange (ETDEWEB)

    Beljaev, Y.V.; Zaitsev, S.I.; Tarankov, G.A. [OKB Gidropress (Russian Federation)

    1995-12-31

    Comparison of the results of calculational analysis with experimental data on water level behaviour in horizontal steam generator (PGV-440) under the conditions with cessation of feedwater supply is presented in the report. Calculational analysis is performed using DIMANIKA-5 code, experimental data are obtained at Kola NPP-4. (orig.). 2 refs.

  12. Verification of Dinamika-5 code on experimental data of water level behaviour in PGV-440 under dynamic conditions

    Energy Technology Data Exchange (ETDEWEB)

    Beljaev, Y V; Zaitsev, S I; Tarankov, G A [OKB Gidropress (Russian Federation)

    1996-12-31

    Comparison of the results of calculational analysis with experimental data on water level behaviour in horizontal steam generator (PGV-440) under the conditions with cessation of feedwater supply is presented in the report. Calculational analysis is performed using DIMANIKA-5 code, experimental data are obtained at Kola NPP-4. (orig.). 2 refs.

  13. The analysis of the annular fuel performance in steady state condition by using AFPAC code

    International Nuclear Information System (INIS)

    He Xiaojun; Ji Songtao; Zhang Yingchao

    2012-01-01

    The fuel performance code AFPAC v1.0 is used to analyze annular fuel's behavior under steady state conditions, including neutronics, thermal hydraulic, rod deformation, fission gas release and rod internal pressure. The calculation results show that: 1) Annular fuel has a good steady irradiation performance at 150% power level as current LWRs' with burnup up to 50 GWd/t, and all parameters, such as temperature, rod internal pressure and rod deformation, are meet the rod design criteria for current fuel of PWRs: 2) Compared to the solid fuel under the same irradiation condition. annular fuel has lower temperature, smaller deformation, lower fission gas release and lower pressure at EOL. From the point of view of steady irradiation performance, the safety of reactors can significantly improved by u sing the annular fuel. (authors)

  14. The RETRAN-03 computer code

    International Nuclear Information System (INIS)

    Paulsen, M.P.; McFadden, J.H.; Peterson, C.E.; McClure, J.A.; Gose, G.C.; Jensen, P.J.

    1991-01-01

    The RETRAN-03 code development effort is designed to overcome the major theoretical and practical limitations associated with the RETRAN-02 computer code. The major objectives of the development program are to extend the range of analyses that can be performed with RETRAN, to make the code more dependable and faster running, and to have a more transportable code. The first two objectives are accomplished by developing new models and adding other models to the RETRAN-02 base code. The major model additions for RETRAN-03 are as follows: implicit solution methods for the steady-state and transient forms of the field equations; additional options for the velocity difference equation; a new steady-state initialization option for computer low-power steam generator initial conditions; models for nonequilibrium thermodynamic conditions; and several special-purpose models. The source code and the environmental library for RETRAN-03 are written in standard FORTRAN 77, which allows the last objective to be fulfilled. Some models in RETRAN-02 have been deleted in RETRAN-03. In this paper the changes between RETRAN-02 and RETRAN-03 are reviewed

  15. Joint design of QC-LDPC codes for coded cooperation system with joint iterative decoding

    Science.gov (United States)

    Zhang, Shunwai; Yang, Fengfan; Tang, Lei; Ejaz, Saqib; Luo, Lin; Maharaj, B. T.

    2016-03-01

    In this paper, we investigate joint design of quasi-cyclic low-density-parity-check (QC-LDPC) codes for coded cooperation system with joint iterative decoding in the destination. First, QC-LDPC codes based on the base matrix and exponent matrix are introduced, and then we describe two types of girth-4 cycles in QC-LDPC codes employed by the source and relay. In the equivalent parity-check matrix corresponding to the jointly designed QC-LDPC codes employed by the source and relay, all girth-4 cycles including both type I and type II are cancelled. Theoretical analysis and numerical simulations show that the jointly designed QC-LDPC coded cooperation well combines cooperation gain and channel coding gain, and outperforms the coded non-cooperation under the same conditions. Furthermore, the bit error rate performance of the coded cooperation employing jointly designed QC-LDPC codes is better than those of random LDPC codes and separately designed QC-LDPC codes over AWGN channels.

  16. On locality of Generalized Reed-Muller codes over the broadcast erasure channel

    KAUST Repository

    Alloum, Amira

    2016-07-28

    One to Many communications are expected to be among the killer applications for the currently discussed 5G standard. The usage of coding mechanisms is impacting broadcasting standard quality, as coding is involved at several levels of the stack, and more specifically at the application layer where Rateless, LDPC, Reed Slomon codes and network coding schemes have been extensively studied, optimized and standardized in the past. Beyond reusing, extending or adapting existing application layer packet coding mechanisms based on previous schemes and designed for the foregoing LTE or other broadcasting standards; our purpose is to investigate the use of Generalized Reed Muller codes and the value of their locality property in their progressive decoding for Broadcast/Multicast communication schemes with real time video delivery. Our results are meant to bring insight into the use of locally decodable codes in Broadcasting. © 2016 IEEE.

  17. Computer modelling of the WWER fuel elements under high burnup conditions by the computer codes PIN-W and RODQ2D

    Energy Technology Data Exchange (ETDEWEB)

    Valach, M; Zymak, J; Svoboda, R [Nuclear Research Inst. Rez plc, Rez (Czech Republic)

    1997-08-01

    This paper presents the development status of the computer codes for the WWER fuel elements thermomechanical behavior modelling under high burnup conditions at the Nuclear Research Institute Rez. The accent is given on the analysis of the results from the parametric calculations, performed by the programmes PIN-W and RODQ2D, rather than on their detailed theoretical description. Several new optional correlations for the UO2 thermal conductivity with degradation effect caused by burnup were implemented into the both codes. Examples of performed calculations document differences between previous and new versions of both programmes. Some recommendations for further development of the codes are given in conclusion. (author). 6 refs, 9 figs.

  18. Computer modelling of the WWER fuel elements under high burnup conditions by the computer codes PIN-W and RODQ2D

    International Nuclear Information System (INIS)

    Valach, M.; Zymak, J.; Svoboda, R.

    1997-01-01

    This paper presents the development status of the computer codes for the WWER fuel elements thermomechanical behavior modelling under high burnup conditions at the Nuclear Research Institute Rez. The accent is given on the analysis of the results from the parametric calculations, performed by the programmes PIN-W and RODQ2D, rather than on their detailed theoretical description. Several new optional correlations for the UO2 thermal conductivity with degradation effect caused by burnup were implemented into the both codes. Examples of performed calculations document differences between previous and new versions of both programmes. Some recommendations for further development of the codes are given in conclusion. (author). 6 refs, 9 figs

  19. Hermitian self-dual quasi-abelian codes

    Directory of Open Access Journals (Sweden)

    Herbert S. Palines

    2017-12-01

    Full Text Available Quasi-abelian codes constitute an important class of linear codes containing theoretically and practically interesting codes such as quasi-cyclic codes, abelian codes, and cyclic codes. In particular, the sub-class consisting of 1-generator quasi-abelian codes contains large families of good codes. Based on the well-known decomposition of quasi-abelian codes, the characterization and enumeration of Hermitian self-dual quasi-abelian codes are given. In the case of 1-generator quasi-abelian codes, we offer necessary and sufficient conditions for such codes to be Hermitian self-dual and give a formula for the number of these codes. In the case where the underlying groups are some $p$-groups, the actual number of resulting Hermitian self-dual quasi-abelian codes are determined.

  20. Adaptive decoding of convolutional codes

    Science.gov (United States)

    Hueske, K.; Geldmacher, J.; Götze, J.

    2007-06-01

    Convolutional codes, which are frequently used as error correction codes in digital transmission systems, are generally decoded using the Viterbi Decoder. On the one hand the Viterbi Decoder is an optimum maximum likelihood decoder, i.e. the most probable transmitted code sequence is obtained. On the other hand the mathematical complexity of the algorithm only depends on the used code, not on the number of transmission errors. To reduce the complexity of the decoding process for good transmission conditions, an alternative syndrome based decoder is presented. The reduction of complexity is realized by two different approaches, the syndrome zero sequence deactivation and the path metric equalization. The two approaches enable an easy adaptation of the decoding complexity for different transmission conditions, which results in a trade-off between decoding complexity and error correction performance.

  1. Studies on the Corrosion Behavior of TiCode-12 with the Variation of Environmental Factors and Heat Treatment Conditions

    International Nuclear Information System (INIS)

    Yoon, S. R.; Kim, T. Y.; Lee, K. H.

    1989-01-01

    Corrosion behavior of TiCode-12 (Ti-0.8Ni-0.3Mo) has been studied by means of electrochemical polarization measurements and corrosion morphology examinations in various corrosive environments and different heat treatment conditions of the alloy. 1N H 2 SO 4 at 45 .deg. C was taken as a standard corrosive solution in which Cl - , Fe 3+ and Br - ion were added to investigate their effects. Acid concentration and temperature were also varied. Polarization behaviors of pure Ti, Ni, Mo and Ti 2 Ni were compared with those of heat-treated TiCode-12 specimens to find out how the constituent elements and the intermetallic compound formed during heat treatment of TiCode-12 affect the corrosion of the alloy. Mill-annealed TiCode-12 showed primary and secondary active-passive transition behavior in all the tested H 2 SO 4 solutions. The former behavior was confirmed to be due to Ti and the latter due to Ni and Mo. The passive current densities increased with increased Cl - ion concentration but decreased reversely beyond certain concentration. Fe 3+ ion raised the corrosion potential of TiCode-12 to the passive region, thus reducing the corrosion rate. Br - ion was turned out to be a critical species to induce the pitting of TiCode-12 by some unknown reason. Cathodic polarization behavior of pure Ni and Ti 2 Ni revealed that hydrogen evolution reaction was promoted on these electrodes in acid media. This was ascribed to the cause for sensitization phenomena of TiCode-12 heat-treated in the temperature range in which the eutectoid reaction β→α + Ti 2 Ni occurs. Near pits, observed on a sensitized TiCode-12 specimen immersed in H 2 SO 4 , always found were β crystals in which Ni peak was detected by EDS

  2. The Redox Code.

    Science.gov (United States)

    Jones, Dean P; Sies, Helmut

    2015-09-20

    The redox code is a set of principles that defines the positioning of the nicotinamide adenine dinucleotide (NAD, NADP) and thiol/disulfide and other redox systems as well as the thiol redox proteome in space and time in biological systems. The code is richly elaborated in an oxygen-dependent life, where activation/deactivation cycles involving O₂ and H₂O₂ contribute to spatiotemporal organization for differentiation, development, and adaptation to the environment. Disruption of this organizational structure during oxidative stress represents a fundamental mechanism in system failure and disease. Methodology in assessing components of the redox code under physiological conditions has progressed, permitting insight into spatiotemporal organization and allowing for identification of redox partners in redox proteomics and redox metabolomics. Complexity of redox networks and redox regulation is being revealed step by step, yet much still needs to be learned. Detailed knowledge of the molecular patterns generated from the principles of the redox code under defined physiological or pathological conditions in cells and organs will contribute to understanding the redox component in health and disease. Ultimately, there will be a scientific basis to a modern redox medicine.

  3. A real-time virtual delivery system for photon radiotherapy delivery monitoring

    Directory of Open Access Journals (Sweden)

    Feng Shi

    2014-03-01

    Full Text Available Purpose: Treatment delivery monitoring is important for radiotherapy, which enables catching dosimetric error at the earliest possible opportunity. This project develops a virtual delivery system to monitor the dose delivery process of photon radiotherapy in real-time using GPU-based Monte Carlo (MC method.Methods: The simulation process consists of 3 parallel CPU threads. A thread T1 is responsible for communication with a linac, which acquires a set of linac status parameters, e.g. gantry angles, MLC configurations, and beam MUs every 20 ms. Since linac vendors currently do not offer interface to acquire data in real time, we mimic this process by fetching information from a linac dynalog file at the set frequency. Instantaneous beam fluence map (FM is calculated based. A FM buffer is also created in T1 and the instantaneous FM is accumulated to it. This process continues, until a ready signal is received from thread T2 on which an in-house developed MC dose engine executes on GPU. At that moment, the accumulated FM is transferred to T2 for dose calculations, and the FM buffer in T1 is cleared. Once the dose calculation finishes, the resulting 3D dose distribution is directed to thread T3, which displays it in three orthogonal planes in color wash overlaid on the CT image. This process continues to monitor the 3D dose distribution in real-time.Results: An IMRT and a VMAT cases used in our patient-specific QA are studied. Maximum dose differences between our system and treatment planning system are 0.98% and 1.58% for the IMRT and VMAT cases, respectively. The update frequency is >10Hz and the relative uncertainty level is 2%.Conclusion: By embedding a GPU-based MC code in a novel data/work flow, it is possible to achieve real-time MC dose calculations to monitor delivery process.------------------------------Cite this article as: Shi F, Gu X, Graves YJ, Jiang S, Jia X. A real-time virtual delivery system for photon radiotherapy delivery

  4. Validation of thermalhydraulic codes

    International Nuclear Information System (INIS)

    Wilkie, D.

    1992-01-01

    Thermalhydraulic codes require to be validated against experimental data collected over a wide range of situations if they are to be relied upon. A good example is provided by the nuclear industry where codes are used for safety studies and for determining operating conditions. Errors in the codes could lead to financial penalties, to the incorrect estimation of the consequences of accidents and even to the accidents themselves. Comparison between prediction and experiment is often described qualitatively or in approximate terms, e.g. ''agreement is within 10%''. A quantitative method is preferable, especially when several competing codes are available. The codes can then be ranked in order of merit. Such a method is described. (Author)

  5. An information theoretic approach to use high-fidelity codes to calibrate low-fidelity codes

    Energy Technology Data Exchange (ETDEWEB)

    Lewis, Allison, E-mail: lewis.allison10@gmail.com [Department of Mathematics, North Carolina State University, Raleigh, NC 27695 (United States); Smith, Ralph [Department of Mathematics, North Carolina State University, Raleigh, NC 27695 (United States); Williams, Brian [Los Alamos National Laboratory, Los Alamos, NM 87545 (United States); Figueroa, Victor [Sandia National Laboratories, Albuquerque, NM 87185 (United States)

    2016-11-01

    For many simulation models, it can be prohibitively expensive or physically infeasible to obtain a complete set of experimental data to calibrate model parameters. In such cases, one can alternatively employ validated higher-fidelity codes to generate simulated data, which can be used to calibrate the lower-fidelity code. In this paper, we employ an information-theoretic framework to determine the reduction in parameter uncertainty that is obtained by evaluating the high-fidelity code at a specific set of design conditions. These conditions are chosen sequentially, based on the amount of information that they contribute to the low-fidelity model parameters. The goal is to employ Bayesian experimental design techniques to minimize the number of high-fidelity code evaluations required to accurately calibrate the low-fidelity model. We illustrate the performance of this framework using heat and diffusion examples, a 1-D kinetic neutron diffusion equation, and a particle transport model, and include initial results from the integration of the high-fidelity thermal-hydraulics code Hydra-TH with a low-fidelity exponential model for the friction correlation factor.

  6. Adaptive decoding of convolutional codes

    Directory of Open Access Journals (Sweden)

    K. Hueske

    2007-06-01

    Full Text Available Convolutional codes, which are frequently used as error correction codes in digital transmission systems, are generally decoded using the Viterbi Decoder. On the one hand the Viterbi Decoder is an optimum maximum likelihood decoder, i.e. the most probable transmitted code sequence is obtained. On the other hand the mathematical complexity of the algorithm only depends on the used code, not on the number of transmission errors. To reduce the complexity of the decoding process for good transmission conditions, an alternative syndrome based decoder is presented. The reduction of complexity is realized by two different approaches, the syndrome zero sequence deactivation and the path metric equalization. The two approaches enable an easy adaptation of the decoding complexity for different transmission conditions, which results in a trade-off between decoding complexity and error correction performance.

  7. MUFITS Code for Modeling Geological Storage of Carbon Dioxide at Sub- and Supercritical Conditions

    Science.gov (United States)

    Afanasyev, A.

    2012-12-01

    Two-phase models are widely used for simulation of CO2 storage in saline aquifers. These models support gaseous phase mainly saturated with CO2 and liquid phase mainly saturated with H2O (e.g. TOUGH2 code). The models can be applied to analysis of CO2 storage only in relatively deeply-buried reservoirs where pressure exceeds CO2 critical pressure. At these supercritical reservoir conditions only one supercritical CO2-rich phase appears in aquifer due to CO2 injection. In shallow aquifers where reservoir pressure is less than the critical pressure CO2 can split in two different liquid-like and gas-like phases (e.g. Spycher et al., 2003). Thus a region of three-phase flow of water, liquid and gaseous CO2 can appear near the CO2 injection point. Today there is no widely used and generally accepted numerical model capable of the three-phase flows with two CO2-rich phases. In this work we propose a new hydrodynamic simulator MUFITS (Multiphase Filtration Transport Simulator) for multiphase compositional modeling of CO2-H2O mixture flows in porous media at conditions of interest for carbon sequestration. The simulator is effective both for supercritical flows in a wide range of pressure and temperature and for subcritical three-phase flows of water, liquid CO2 and gaseous CO2 in shallow reservoirs. The distinctive feature of the proposed code lies in the methodology for mixture properties determination. Transport equations and Darcy correlation are solved together with calculation of the entropy maximum that is reached in thermodynamic equilibrium and determines the mixture composition. To define and solve the problem only one function - mixture thermodynamic potential - is required. The potential is determined using a three-parametric generalization of Peng-Robinson equation of state fitted to experimental data (Todheide, Takenouchi, Altunin etc.). We apply MUFITS to simple 1D and 2D test problems of CO2 injection in shallow reservoirs subjected to phase changes between

  8. Ensemble Weight Enumerators for Protograph LDPC Codes

    Science.gov (United States)

    Divsalar, Dariush

    2006-01-01

    Recently LDPC codes with projected graph, or protograph structures have been proposed. In this paper, finite length ensemble weight enumerators for LDPC codes with protograph structures are obtained. Asymptotic results are derived as the block size goes to infinity. In particular we are interested in obtaining ensemble average weight enumerators for protograph LDPC codes which have minimum distance that grows linearly with block size. As with irregular ensembles, linear minimum distance property is sensitive to the proportion of degree-2 variable nodes. In this paper the derived results on ensemble weight enumerators show that linear minimum distance condition on degree distribution of unstructured irregular LDPC codes is a sufficient but not a necessary condition for protograph LDPC codes.

  9. Therapeutic targeting of non-coding RNAs in cancer

    Czech Academy of Sciences Publication Activity Database

    Slabý, O.; Laga, Richard; Sedláček, Ondřej

    2017-01-01

    Roč. 474, č. 24 (2017), s. 4219-4251 ISSN 0264-6021 R&D Projects: GA MŠk(CZ) LQ1604; GA MŠk(CZ) ED1.1.00/02.0109 Institutional support: RVO:61389013 Keywords : non-coding RNA * RNA delivery * polymer carriers Subject RIV: EB - Genetics ; Molecular Biology OBOR OECD: Biochemical research methods Impact factor: 3.797, year: 2016

  10. The modeling of fuel rod behaviour under RIA conditions in the code DYN3D

    International Nuclear Information System (INIS)

    Rohde, U.

    1998-01-01

    A description of the fuel rod behaviour and heat transfer model used in the code DYN3D for nuclear reactor core dynamic simulations is given. Besides the solution of heat conduction equations in fuel and cladding, the model comprises detailed description of heat transfer in the gas gap by conduction, radiation and fuel-cladding contact. The gas gap behaviour is modeled in a mechanistic way taking into account transient changes of the gas gap parameters based on given conditions for the initial state. Thermal, elastic and plastic deformations of fuel and cladding are taken into account within 1D approximation. Numerical studies concerning the fuel rod behaviour under RIA conditions in power reactors are reported. Fuel rod behaviour at high pressures and flow rates in power reactors is different from the behaviour under atmospheric pressure and stagnant flow conditions in the experiments. The mechanisms of fuel rod failure for fresh and burned fuel reported from the literature can be qualitatively reproduced by the DYN3D model. (author)

  11. Interface requirements for coupling a containment code to a reactor system thermal hydraulic codes

    International Nuclear Information System (INIS)

    Baratta, A.J.

    1997-01-01

    To perform a complete analysis of a reactor transient, not only the primary system response but the containment response must also be accounted for. Such transients and accidents as a loss of coolant accident in both pressurized water and boiling water reactors and inadvertent operation of safety relief valves all challenge the containment and may influence flows because of containment feedback. More recently, the advanced reactor designs put forth by General Electric and Westinghouse in the US and by Framatome and Seimens in Europe rely on the containment to act as the ultimate heat sink. Techniques used by analysts and engineers to analyze the interaction of the containment and the primary system were usually iterative in nature. Codes such as RELAP or RETRAN were used to analyze the primary system response and CONTAIN or CONTEMPT the containment response. The analysis was performed by first running the system code and representing the containment as a fixed pressure boundary condition. The flows were usually from the primary system to the containment initially and generally under choked conditions. Once the mass flows and timing are determined from the system codes, these conditions were input into the containment code. The resulting pressures and temperatures were then calculated and the containment performance analyzed. The disadvantage of this approach becomes evident when one performs an analysis of a rapid depressurization or a long term accident sequence in which feedback from the containment can occur. For example, in a BWR main steam line break transient, the containment heats up and becomes a source of energy for the primary system. Recent advances in programming and computer technology are available to provide an alternative approach. The author and other researchers have developed linkage codes capable of transferring data between codes at each time step allowing discrete codes to be coupled together

  12. Interface requirements for coupling a containment code to a reactor system thermal hydraulic codes

    Energy Technology Data Exchange (ETDEWEB)

    Baratta, A.J.

    1997-07-01

    To perform a complete analysis of a reactor transient, not only the primary system response but the containment response must also be accounted for. Such transients and accidents as a loss of coolant accident in both pressurized water and boiling water reactors and inadvertent operation of safety relief valves all challenge the containment and may influence flows because of containment feedback. More recently, the advanced reactor designs put forth by General Electric and Westinghouse in the US and by Framatome and Seimens in Europe rely on the containment to act as the ultimate heat sink. Techniques used by analysts and engineers to analyze the interaction of the containment and the primary system were usually iterative in nature. Codes such as RELAP or RETRAN were used to analyze the primary system response and CONTAIN or CONTEMPT the containment response. The analysis was performed by first running the system code and representing the containment as a fixed pressure boundary condition. The flows were usually from the primary system to the containment initially and generally under choked conditions. Once the mass flows and timing are determined from the system codes, these conditions were input into the containment code. The resulting pressures and temperatures were then calculated and the containment performance analyzed. The disadvantage of this approach becomes evident when one performs an analysis of a rapid depressurization or a long term accident sequence in which feedback from the containment can occur. For example, in a BWR main steam line break transient, the containment heats up and becomes a source of energy for the primary system. Recent advances in programming and computer technology are available to provide an alternative approach. The author and other researchers have developed linkage codes capable of transferring data between codes at each time step allowing discrete codes to be coupled together.

  13. Synthesizing Certified Code

    Science.gov (United States)

    Whalen, Michael; Schumann, Johann; Fischer, Bernd

    2002-01-01

    Code certification is a lightweight approach to demonstrate software quality on a formal level. Its basic idea is to require producers to provide formal proofs that their code satisfies certain quality properties. These proofs serve as certificates which can be checked independently. Since code certification uses the same underlying technology as program verification, it also requires many detailed annotations (e.g., loop invariants) to make the proofs possible. However, manually adding theses annotations to the code is time-consuming and error-prone. We address this problem by combining code certification with automatic program synthesis. We propose an approach to generate simultaneously, from a high-level specification, code and all annotations required to certify generated code. Here, we describe a certification extension of AUTOBAYES, a synthesis tool which automatically generates complex data analysis programs from compact specifications. AUTOBAYES contains sufficient high-level domain knowledge to generate detailed annotations. This allows us to use a general-purpose verification condition generator to produce a set of proof obligations in first-order logic. The obligations are then discharged using the automated theorem E-SETHEO. We demonstrate our approach by certifying operator safety for a generated iterative data classification program without manual annotation of the code.

  14. Efficiency and economics of hydrogen delivery

    International Nuclear Information System (INIS)

    Liu, Y.; Bharadwaj, R.; Balan, C.; Garces, L.; Smith, D.

    2003-01-01

    The viability and penetration of fuel cell based electricity production will be mainly determined by the efficient, cost effective production and delivery of hydrogen. This study focuses on the transportation efficiency and cost of hydrogen delivery for both centrally produced hydrogen as well as electricity scenarios. The efficiency and economics of energy delivery depend on the quantity of energy to be transported and transportation distance. Energy delivery models were developed for Hydrogen delivery as compressed gas or cryogenic liquid using truck or pipeline. For comparison, models were also developed for high voltage AC electricity transmission. Major parameters that influence the performance of the energy transmission systems under normal operating conditions were modeled. The models use energy transported and delivery distance as independent variables. The results were validated against similar reports, government surveys and other publications. Energy delivery efficiency and costs were used to compare and evaluate the different delivery options. Effect of uncertainty and sensitivity of parameters on modeling results were also studied. The systems were compared on an equivalent basis. The analysis also identifies the trade-offs for electricity transmission and electrolysis application at the point of use for Hydrogen delivery. These results provide a consistent framework for evaluation of delivery options on energy efficiency basis. (author)

  15. Coding with partially hidden Markov models

    DEFF Research Database (Denmark)

    Forchhammer, Søren; Rissanen, J.

    1995-01-01

    Partially hidden Markov models (PHMM) are introduced. They are a variation of the hidden Markov models (HMM) combining the power of explicit conditioning on past observations and the power of using hidden states. (P)HMM may be combined with arithmetic coding for lossless data compression. A general...... 2-part coding scheme for given model order but unknown parameters based on PHMM is presented. A forward-backward reestimation of parameters with a redefined backward variable is given for these models and used for estimating the unknown parameters. Proof of convergence of this reestimation is given....... The PHMM structure and the conditions of the convergence proof allows for application of the PHMM to image coding. Relations between the PHMM and hidden Markov models (HMM) are treated. Results of coding bi-level images with the PHMM coding scheme is given. The results indicate that the PHMM can adapt...

  16. SMART POLYMERS: INNOVATIONS IN NOVEL DRUG DELIVERY

    OpenAIRE

    Apoorva Mahajan; Geeta Aggarwal

    2011-01-01

    Smart polymers are attracting the researchers for development of novel drug delivery systems. Importance of smart polymers is rising day by day as these polymers undergo large reversible, physical or chemical changes in response to small changes in the environmental conditions such as pH, temperature, dual- stimuli, light and phase transition. Smart polymers are representing promising means for targeted drug delivery, enhanced drug delivery, gene therapy, actuator stimuli and protein folders....

  17. The Aesthetics of Coding

    DEFF Research Database (Denmark)

    Andersen, Christian Ulrik

    2007-01-01

    Computer art is often associated with computer-generated expressions (digitally manipulated audio/images in music, video, stage design, media facades, etc.). In recent computer art, however, the code-text itself – not the generated output – has become the artwork (Perl Poetry, ASCII Art, obfuscated...... code, etc.). The presentation relates this artistic fascination of code to a media critique expressed by Florian Cramer, claiming that the graphical interface represents a media separation (of text/code and image) causing alienation to the computer’s materiality. Cramer is thus the voice of a new ‘code...... avant-garde’. In line with Cramer, the artists Alex McLean and Adrian Ward (aka Slub) declare: “art-oriented programming needs to acknowledge the conditions of its own making – its poesis.” By analysing the Live Coding performances of Slub (where they program computer music live), the presentation...

  18. Protein-Based Drug-Delivery Materials

    OpenAIRE

    Jao, Dave; Xue, Ye; Medina, Jethro; Hu, Xiao

    2017-01-01

    There is a pressing need for long-term, controlled drug release for sustained treatment of chronic or persistent medical conditions and diseases. Guided drug delivery is difficult because therapeutic compounds need to survive numerous transport barriers and binding targets throughout the body. Nanoscale protein-based polymers are increasingly used for drug and vaccine delivery to cross these biological barriers and through blood circulation to their molecular site of action. Protein-based pol...

  19. Computer codes for ventilation in nuclear facilities

    International Nuclear Information System (INIS)

    Mulcey, P.

    1987-01-01

    In this paper the authors present some computer codes, developed in the last years, for ventilation and radioprotection. These codes are used for safety analysis in the conception, exploitation and dismantlement of nuclear facilities. The authors present particularly: DACC1 code used for aerosol deposit in sampling circuit of radiation monitors; PIAF code used for modelization of complex ventilation system; CLIMAT 6 code used for optimization of air conditioning system [fr

  20. Methodology, status and plans for development and assessment of Cathare code

    Energy Technology Data Exchange (ETDEWEB)

    Bestion, D.; Barre, F.; Faydide, B. [CEA - Grenoble (France)

    1997-07-01

    This paper presents the methodology, status and plans for the development, assessment and uncertainty evaluation of the Cathare code. Cathare is a thermalhydraulic code developed by CEA (DRN), IPSN, EDF and FRAMATOME for PWR safety analysis. First, the status of the code development and assessment is presented. The general strategy used for the development and the assessment of the code is presented. Analytical experiments with separate effect tests, and component tests are used for the development and the validation of closure laws. Successive Revisions of constitutive laws are implemented in successive Versions of the code and assessed. System tests or integral tests are used to validate the general consistency of the Revision. Each delivery of a code Version + Revision is fully assessed and documented. A methodology is being developed to determine the uncertainty on all constitutive laws of the code using calculations of many analytical tests and applying the Discrete Adjoint Sensitivity Method (DASM). At last, the plans for the future developments of the code are presented. They concern the optimization of the code performance through parallel computing - the code will be used for real time full scope plant simulators - the coupling with many other codes (neutronic codes, severe accident codes), the application of the code for containment thermalhydraulics. Also, physical improvements are required in the field of low pressure transients and in the modeling for the 3-D model.

  1. Conservation of concrete structures according to fib Model Code 2010

    NARCIS (Netherlands)

    Matthews, S.; Bigaj-Van Vliet, A.; Ueda, T.

    2013-01-01

    Conservation of concrete structures forms an essential part of the fib Model Code for Concrete Structures 2010 (fib Model Code 2010). In particular, Chapter 9 of fib Model Code 2010 addresses issues concerning conservation strategies and tactics, conservation management, condition surveys, condition

  2. Non-technical skills for obstetricians conducting forceps and vacuum deliveries: qualitative analysis by interviews and video recordings.

    Science.gov (United States)

    Bahl, Rachna; Murphy, Deirdre J; Strachan, Bryony

    2010-06-01

    Non-technical skills are cognitive and social skills required in an operational task. These skills have been identified and taught in the surgical domain but are of particular relevance to obstetrics where the patient is awake, the partner is present and the clinical circumstances are acute and often stressful. The aim of this study was to define the non-technical skills of an operative vaginal delivery (forceps or vacuum) to facilitate transfer of skills from expert obstetricians to trainee obstetricians. Qualitative study using interviews and video recordings. The study was conducted at two university teaching hospitals (St. Michael's Hospital, Bristol and Ninewells Hospital, Dundee). Participants included 10 obstetricians and eight midwives identified as experts in conducting or supporting operative vaginal deliveries. Semi-structured interviews were carried out using routine clinical scenarios. The experts were also video recorded conducting forceps and vacuum deliveries in a simulation setting. The interviews and video recordings were transcribed verbatim and analysed using thematic coding. The anonymised data were independently coded by the three researchers and then compared for consistency of interpretation. The experts reviewed the coded data for respondent validation and clarification. The themes that emerged were used to identify the non-technical skills required for conducting an operative vaginal delivery. The final skills list was classified into seven main categories. Four categories (situational awareness, decision making, task management, and team work and communication) were similar to the categories identified in surgery. Three further categories unique to obstetrics were also identified (professional relationship with the woman, maintaining professional behaviour and cross-monitoring of performance). This explicitly defined skills taxonomy could aid trainees' understanding of the non-technical skills to be considered when conducting an operative

  3. [Footwear according to the "business dress code", and the health condition of women's feet--computer-assisted holistic evaluation].

    Science.gov (United States)

    Lorkowski, Jacek; Mrzygłód, Mirosław; Kotela, Ireneusz; Kiełbasiewicz-Lorkowska, Ewa; Teul, Iwona

    2013-01-01

    According to the verdict of the Supreme Court in 2005, an employer may dismiss an employee if their conduct (including dress) exposes the employer to losses or threatens his interests. The aim of the study was a holistic assessment of the pleiotropic effects of high-heeled pointed shoes on the health condition of women's feet, wearing them at work, in accordance with the existing rules of the "business dress code". A holistic multidisciplinary analysis was performed. It takes into account: 1) women employees of banks and other large corporations (82 persons); 2) 2D FEM computer model developed by the authors of foot deformed by pointed high-heeled shoes; 3) web site found after entering the code "business dress code". Over 60% of women in the office wore high-heeled shoes. The following has been found among people walking to work in high heels: 1) reduction in the quality of life in about 70% of cases, through periodic occurrence of pain and reduction of functional capacity of the feet; 2) increase in the pressure on the plantar side of the forefoot at least twice; 3) the continued effects the forces deforming the forefoot. 1. An evolutionary change of "dress code" shoes is necessary in order to lead to a reduction in non-physiological overload of feet and the consequence of their disability. 2. These changes are particularly urgent in patients with so-called "sensitive foot".

  4. Documentation of the heat conduction code TRANCO

    International Nuclear Information System (INIS)

    Callahan, G.D.

    1975-01-01

    A transient heat conduction code used for thermal, thermoelastic, thermoelastic/plastic, and thermo/viscoelastic analyses is presented. The code can solve two-dimensional X-Y and axially symmetric R-theta-z thermal problems with the following conditions: constant temperature, constant flux, convective, or adiabatic boundary conditions; time-dependent or constant internal heat generation; and anisotropic thermal conductivities

  5. 48 CFR 52.211-9 - Desired and Required Time of Delivery.

    Science.gov (United States)

    2010-10-01

    ... and rejected. (End of clause) Alternate I (APR 1984). If the delivery schedule is expressed in terms... the ordinary mails. Alternate II (APR 1984). If the delivery schedule is expressed in terms of... that propose delivery of a quantity under such terms or conditions that delivery will not clearly fall...

  6. Code Modernization of VPIC

    Science.gov (United States)

    Bird, Robert; Nystrom, David; Albright, Brian

    2017-10-01

    The ability of scientific simulations to effectively deliver performant computation is increasingly being challenged by successive generations of high-performance computing architectures. Code development to support efficient computation on these modern architectures is both expensive, and highly complex; if it is approached without due care, it may also not be directly transferable between subsequent hardware generations. Previous works have discussed techniques to support the process of adapting a legacy code for modern hardware generations, but despite the breakthroughs in the areas of mini-app development, portable-performance, and cache oblivious algorithms the problem still remains largely unsolved. In this work we demonstrate how a focus on platform agnostic modern code-development can be applied to Particle-in-Cell (PIC) simulations to facilitate effective scientific delivery. This work builds directly on our previous work optimizing VPIC, in which we replaced intrinsic based vectorisation with compile generated auto-vectorization to improve the performance and portability of VPIC. In this work we present the use of a specialized SIMD queue for processing some particle operations, and also preview a GPU capable OpenMP variant of VPIC. Finally we include a lessons learnt. Work performed under the auspices of the U.S. Dept. of Energy by the Los Alamos National Security, LLC Los Alamos National Laboratory under contract DE-AC52-06NA25396 and supported by the LANL LDRD program.

  7. Establishment of Technical Collaboration basis between Korea and France for the development of severe accident assessment computer code under high burnup condition

    International Nuclear Information System (INIS)

    Kim, H. D.; Kim, D. H.; Park, S. Y.; Park, J. H.

    2005-10-01

    This project was performed by KAERI in the frame of construction of the international cooperative basis on the nuclear energy. This was supported from MOST under the title of 'Establishment of Technical Collaboration basis between Korea and France for the development of severe accident assessment computer code under high burn up condition'. The current operating NPP are converting the burned fuel to the wasted fuel after burn up of 40 GWD/MTU. But in Korea, burn up of more than 60 GWD/MTU will be expected because of the high fuel efficiency but also cost saving for storing the wasted fuel safely. The domestic research for the purpose of developing the fuel and the cladding that can be used under the high burn up condition up to 100 GWD/MTU is in progress now. But the current computer code adopts the model and the data that are valid only up to the 40 GWD/MTU at most. Therefore the current model could not take into account the phenomena that may cause differences in the fission product release behavior or in the core damage process due to the high burn up operation (more than 40 GWD/MTU). To evaluate the safety of the NPP with the high burn up fuel, the improvement of current severe accident code against the high burn up condition is an important research item. Also it should start without any delay. Therefore, in this study, an expert group was constructed to establish the research basis for the severe accident under high burn up conditions. From this expert group, the research items regarding the high burn up condition were selected and identified through discussion and technical seminars. Based on these selected items, the meeting between IRSN and KAERI to find out the cooperative research items on the severe accident under the high burn up condition was held in the IRSN headquater in Paris. After the meeting, KAERI and IRSN agreed to cooperate with each other on the selected items, and to co-host the international seminar, and to develop the model and to

  8. Non-binary Entanglement-assisted Stabilizer Quantum Codes

    OpenAIRE

    Riguang, Leng; Zhi, Ma

    2011-01-01

    In this paper, we show how to construct non-binary entanglement-assisted stabilizer quantum codes by using pre-shared entanglement between the sender and receiver. We also give an algorithm to determine the circuit for non-binary entanglement-assisted stabilizer quantum codes and some illustrated examples. The codes we constructed do not require the dual-containing constraint, and many non-binary classical codes, like non-binary LDPC codes, which do not satisfy the condition, can be used to c...

  9. Level-2 Milestone 6007: Sierra Early Delivery System Deployed to Secret Restricted Network

    Energy Technology Data Exchange (ETDEWEB)

    Bertsch, A. D. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2017-09-06

    This report documents the delivery and installation of Shark, a CORAL Sierra early delivery system deployed on the LLNL SRD network. Early ASC program users have run codes on the machine in support of application porting for the final Sierra system which will be deployed at LLNL in CY2018. In addition to the SRD resource, Shark, unclassified resources, Rzmanta and Ray, have been deployed on the LLNL Restricted Zone and Collaboration Zone networks in support of application readiness for the Sierra platform.

  10. Cesarean delivery on maternal request.

    Science.gov (United States)

    Viswanathan, Meera; Visco, Anthony G; Hartmann, Katherine; Wechter, Mary Ellen; Gartlehner, Gerald; Wu, Jennifer M; Palmieri, Rachel; Funk, Michele Jonsson; Lux, Linda; Swinson, Tammeka; Lohr, Kathleen N

    2006-03-01

    The RTI International-University of North Carolina at Chapel Hill Evidence-based Practice Center (RTI-UNC EPC) systematically reviewed the evidence on the trend and incidence of cesarean delivery (CD) in the United States and in other developed countries, maternal and infant outcomes of cesarean delivery on maternal request (CDMR) compared with planned vaginal delivery (PVD), factors affecting the magnitude of the benefits and harms of CDMR, and future research directions. We searched MEDLINE, Cochrane Collaboration resources, and Embase and identified 1,406 articles to examine against a priori inclusion criteria. We included studies published from 1990 to the present, written in English. Studies had to include comparison between the key reference group (CDMR or proxies) and PVD. A primary reviewer abstracted detailed data on key variables from included articles; a second senior reviewer confirmed accuracy. We identified 13 articles for trends and incidence of CD, 54 for maternal and infant outcomes, and 5 on modifiers of CDMR. The incidence of CDMR appears to be increasing. However, accurately assessing either its true incidence or trends over time is difficult because currently CDMR is neither a well-recognized clinical entity nor an accurately reported indication for diagnostic coding or reimbursement. Virtually no studies exist on CDMR, so the knowledge base rests chiefly on indirect evidence from proxies possessing unique and significant limitations. Furthermore, most studies compared outcomes by actual routes of delivery, resulting in great uncertainty as to their relevance to planned routes of delivery. Primary CDMR and planned vaginal delivery likely do differ with respect to individual outcomes for either mothers or infants. However, our comprehensive assessment, across many different outcomes, suggests that no major differences exist between primary CDMR and planned vaginal delivery, but the evidence is too weak to conclude definitively that differences

  11. The Coding Question.

    Science.gov (United States)

    Gallistel, C R

    2017-07-01

    Recent electrophysiological results imply that the duration of the stimulus onset asynchrony in eyeblink conditioning is encoded by a mechanism intrinsic to the cerebellar Purkinje cell. This raises the general question - how is quantitative information (durations, distances, rates, probabilities, amounts, etc.) transmitted by spike trains and encoded into engrams? The usual assumption is that information is transmitted by firing rates. However, rate codes are energetically inefficient and computationally awkward. A combinatorial code is more plausible. If the engram consists of altered synaptic conductances (the usual assumption), then we must ask how numbers may be written to synapses. It is much easier to formulate a coding hypothesis if the engram is realized by a cell-intrinsic molecular mechanism. Copyright © 2017 Elsevier Ltd. All rights reserved.

  12. Use of Electronic Nicotine Delivery Systems among Adults with Mental Health Conditions, 2015

    Directory of Open Access Journals (Sweden)

    Claire Adams Spears

    2016-12-01

    Full Text Available Adults with mental health conditions (MHC are especially likely to smoke and experience tobacco-related health disparities. Individuals with MHC may also use electronic nicotine delivery devices (ENDS at disproportionately high rates. However, there is a relative dearth of knowledge regarding ENDS use among individuals with MHC. In a large representative sample of U.S. adults (n = 6051, associations between self-reported MHC diagnoses and ENDS use and susceptibility were examined, stratified by smoking status. Participants with MHC were approximately 1.5 times more likely to have used ENDS in their lifetime and almost twice as likely to currently use ENDS as those without MHC. MHC status was most strongly linked to higher ENDS use among former smokers, and former smokers with MHC were more likely to report using ENDS during past smoking quit attempts than those without MHC. Among participants who had not tried ENDS, former smokers with MHC were especially susceptible to future ENDS use. The potential advantage of ENDS for cessation purposes should be balanced with the risk of attracting former smokers with MHC to ENDS.

  13. Application of the SCANAIR code for VVER RIA conditions - Boron dilution accident

    International Nuclear Information System (INIS)

    Arffman, A.; Cazalis, B.

    2010-01-01

    This paper consists of two parts. In part A, RIA pulse tests conducted at the Russian BIGR reactor are being analysed at IRSN with SCANAIR V6 fuel performance code as a part of the code validation for VVER fuel. Recently a new version of the SCANAIR code was made available to VTT Technical Research Centre of Finland, and part B of the paper covers the introduction of the code version at VTT by a calculation of a hypothetical boron dilution accident in a VVER-440 power reactor. Concerning part A, it appears that the SCANAIR V6 version, including a BIGR/NSRR heat transfer model, validated by Japanese NSRR experiments, and a Norton viscoplastic clad mechanical behaviour, is able to simulate the rod thermal behaviour in BIGR tests. Concerning the clad mechanics, it has been seen that a pellet swelling model is able to simulate the average rod deformation. Nonetheless, the current clad creep model associated with the free volume equilibrium assumption is not suited to predict the maximum clad deformation and the possible post DNB rod failure because they do not simulate local balloons. Furthermore, it has been shown that the clad deformation is strongly dependent on transient gas transfer. Concerning part B, a boron dilution accident previously calculated with SCANAIR V2 was recalculated with SCANAIR V6. A limited amount of result parameters were compared with the results of VTT's neutronics code TRAB. Divergence problems encountered previously when reaching the DNB limit were not present anymore. Fuel and cladding temperatures produced by SCANAIR were in good agreement with those calculated with TRAB

  14. Association of the position of a hospital-acquired condition diagnosis code with changes in medicare severity diagnosis-related group assignment.

    Science.gov (United States)

    Johnson, Tricia; Kane, Jason M; Odwazny, Richard; McNutt, Robert

    2014-11-01

    Incentives to improve quality include paying less for adverse events, including the Centers for Medicare and Medicaid Services' policy to not pay additionally for events classified as hospital-acquired conditions (HACs). This policy is controversial, as variable coding practices at hospitals may lead to differences in the inclusion and position of HACs in the list of codes used for Medicare Severity Diagnosis-Related Group (MS-DRG) assignment. Evaluate changes in MS-DRG assignment for patients with an HAC and test the association of the position of an HAC in the list of International Classification of Diseases, 9th Revision (ICD-9) diagnosis codes with change in MS-DRG assignment. Retrospective analysis of patients discharged from hospital members of the University HealthSystem Consortium's Clinical Data Base between October 2007 and April 2008. Comparisons were made between the MS-DRG assigned when the HAC was not included in the list of ICD-9 diagnosis codes and the MS-DRG that would have been assigned had the HAC code been included in the assignment. Of the 7027 patients with an HAC, 13.8% changed MS-DRG assignment when the HAC was removed. An HAC in the second position versus third position or lower was associated with a 40-fold increase in the likelihood of MS-DRG change. The position of an HAC in the list of diagnosis codes, rather than the presence of an HAC, is associated with a change in MS-DRG assignment. HACs have little effect on reimbursement unless the HAC is in the second position and patients have minor severity of illness. © 2014 Society of Hospital Medicine.

  15. Development of RETRAN-03/MOV code for thermal-hydraulic analysis of nuclear reactor under moving conditions

    International Nuclear Information System (INIS)

    Kim, Hak Jae; Park, Goon Cherl

    1996-01-01

    Nuclear ship reactors have several; features different from land-based PWR's. Especially, effects of ship motions on reactor thermal-hydraulics and good load following capability for abrupt load changes are essential characteristics of nuclear ship reactors. This study modified the RETRAN-03 to analyze the thermal-hydraulic transients under three-dimensional ship motions, named RETRAN-03/MOV in order to apply to future marine reactors. First Japanese nuclear ship MUTSU reactor have been analyzed under various ship motions to verify this code. Calculations have been performed under rolling,heaving and stationary inclination conditions during normal operation. Also, the natural circulation has been analyzed, which can provide the decay heat removed to ensure the passive safety of marine reactors. As results, typical thermal-hydraulic characteristics of marine reactors such as flow rate oscillations and S/G water level oscillations have been successfully simulated at various conditions. 7 refs., 11 figs. (author)

  16. Challenges and opportunities in dermal/transdermal delivery

    Science.gov (United States)

    Paudel, Kalpana S; Milewski, Mikolaj; Swadley, Courtney L; Brogden, Nicole K; Ghosh, Priyanka; Stinchcomb, Audra L

    2010-01-01

    Transdermal drug delivery is an exciting and challenging area. There are numerous transdermal delivery systems currently available on the market. However, the transdermal market still remains limited to a narrow range of drugs. Further advances in transdermal delivery depend on the ability to overcome the challenges faced regarding the permeation and skin irritation of the drug molecules. Emergence of novel techniques for skin permeation enhancement and development of methods to lessen skin irritation would widen the transdermal market for hydrophilic compounds, macromolecules and conventional drugs for new therapeutic indications. As evident from the ongoing clinical trials of a wide variety of drugs for various clinical conditions, there is a great future for transdermal delivery of drugs. PMID:21132122

  17. On Coding Non-Contiguous Letter Combinations

    Directory of Open Access Journals (Sweden)

    Frédéric eDandurand

    2011-06-01

    Full Text Available Starting from the hypothesis that printed word identification initially involves the parallel mapping of visual features onto location-specific letter identities, we analyze the type of information that would be involved in optimally mapping this location-specific orthographic code onto a location-invariant lexical code. We assume that some intermediate level of coding exists between individual letters and whole words, and that this involves the representation of letter combinations. We then investigate the nature of this intermediate level of coding given the constraints of optimality. This intermediate level of coding is expected to compress data while retaining as much information as possible about word identity. Information conveyed by letters is a function of how much they constrain word identity and how visible they are. Optimization of this coding is a combination of minimizing resources (using the most compact representations and maximizing information. We show that in a large proportion of cases, non-contiguous letter sequences contain more information than contiguous sequences, while at the same time requiring less precise coding. Moreover, we found that the best predictor of human performance in orthographic priming experiments was within-word ranking of conditional probabilities, rather than average conditional probabilities. We conclude that from an optimality perspective, readers learn to select certain contiguous and non-contiguous letter combinations as information that provides the best cue to word identity.

  18. Contributing Indications to the Rising Cesarean Delivery Rate

    Science.gov (United States)

    BARBER, Emma L.; LUNDSBERG, Lisbet; BELANGER, Kathleen; PETTKER, Christian M.; FUNAI, Edmund F.; ILLUZZI, Jessica L.

    2013-01-01

    OBJECTIVE To examine physician-documented indications for cesarean delivery in order to investigate the specific indications contributing to this increase. METHODS We analyzed rates of primary and repeat cesarean delivery, including indications for the procedure, among 32,443 live births at a major academic hospital between 2003–2009. Time trends for each indication were modeled to estimate the absolute and cumulative annualized relative risk of cesarean by indication over time and the relative contribution of each indication to the overall increase in primary cesarean delivery rate. RESULTS The cesarean delivery rate increased from 26% to 36.5% between 2003 and 2009; 50.0% of the increase was attributable to an increase in primary cesarean delivery. Among the documented indications, nonreassuring fetal status, arrest of dilation, multiple gestation, pre-eclampsia, suspected macrosomia, and maternal request increased over time, while arrest of descent, malpresentation, maternal-fetal indications, and other obstetric indications (eg, cord prolapse, placenta previa) did not increase. The relative contributions of each indication to the total increase in primary cesarean rate were: Non-reassuring fetal status (32%), labor arrest disorders (18%), multiple gestation (16%), suspected macrosomia (10%), pre-eclampsia (10%), maternal request (8%), maternal-fetal conditions (5%), and other obstetric conditions (1%). CONCLUSION Primary cesarean births accounted for 50% of the increasing cesarean rate. Among primary cesareans, more subjective indications (nonreassuring fetal status and arrest of dilation) contributed larger proportions than more objective indications (malpresentation, maternal-fetal, and obstetric conditions). PMID:21646928

  19. Quality correction factors of composite IMRT beam deliveries: Theoretical considerations

    International Nuclear Information System (INIS)

    Bouchard, Hugo

    2012-01-01

    Purpose: In the scope of intensity modulated radiation therapy (IMRT) dosimetry using ionization chambers, quality correction factors of plan-class-specific reference (PCSR) fields are theoretically investigated. The symmetry of the problem is studied to provide recommendable criteria for composite beam deliveries where correction factors are minimal and also to establish a theoretical limit for PCSR delivery k Q factors. Methods: The concept of virtual symmetric collapsed (VSC) beam, being associated to a given modulated composite delivery, is defined in the scope of this investigation. Under symmetrical measurement conditions, any composite delivery has the property of having a k Q factor identical to its associated VSC beam. Using this concept of VSC, a fundamental property of IMRT k Q factors is demonstrated in the form of a theorem. The sensitivity to the conditions required by the theorem is thoroughly examined. Results: The theorem states that if a composite modulated beam delivery produces a uniform dose distribution in a volume V cyl which is symmetric with the cylindrical delivery and all beams fulfills two conditions in V cyl : (1) the dose modulation function is unchanged along the beam axis, and (2) the dose gradient in the beam direction is constant for a given lateral position; then its associated VSC beam produces no lateral dose gradient in V cyl , no matter what beam modulation or gantry angles are being used. The examination of the conditions required by the theorem lead to the following results. The effect of the depth-dose gradient not being perfectly constant with depth on the VSC beam lateral dose gradient is found negligible. The effect of the dose modulation function being degraded with depth on the VSC beam lateral dose gradient is found to be only related to scatter and beam hardening, as the theorem holds also for diverging beams. Conclusions: The use of the symmetry of the problem in the present paper leads to a valuable theorem showing

  20. Geochemical computer codes. A review

    International Nuclear Information System (INIS)

    Andersson, K.

    1987-01-01

    In this report a review of available codes is performed and some code intercomparisons are also discussed. The number of codes treating natural waters (groundwater, lake water, sea water) is large. Most geochemical computer codes treat equilibrium conditions, although some codes with kinetic capability are available. A geochemical equilibrium model consists of a computer code, solving a set of equations by some numerical method and a data base, consisting of thermodynamic data required for the calculations. There are some codes which treat coupled geochemical and transport modeling. Some of these codes solve the equilibrium and transport equations simultaneously while other solve the equations separately from each other. The coupled codes require a large computer capacity and have thus as yet limited use. Three code intercomparisons have been found in literature. It may be concluded that there are many codes available for geochemical calculations but most of them require a user that us quite familiar with the code. The user also has to know the geochemical system in order to judge the reliability of the results. A high quality data base is necessary to obtain a reliable result. The best results may be expected for the major species of natural waters. For more complicated problems, including trace elements, precipitation/dissolution, adsorption, etc., the results seem to be less reliable. (With 44 refs.) (author)

  1. Development of steam explosion simulation code JASMINE

    Energy Technology Data Exchange (ETDEWEB)

    Moriyama, Kiyofumi; Yamano, Norihiro; Maruyama, Yu; Kudo, Tamotsu; Sugimoto, Jun [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; Nagano, Katsuhiro; Araki, Kazuhiro

    1995-11-01

    A steam explosion is considered as a phenomenon which possibly threatens the integrity of the containment vessel of a nuclear power plant in a severe accident condition. A numerical calculation code JASMINE (JAeri Simulator for Multiphase INteraction and Explosion) purposed to simulate the whole process of steam explosions has been developed. The premixing model is based on a multiphase flow simulation code MISTRAL by Fuji Research Institute Co. In JASMINE code, the constitutive equations and the flow regime map are modified for the simulation of premixing related phenomena. The numerical solution method of the original code is succeeded, i.e. the basic equations are discretized semi-implicitly, BCGSTAB method is used for the matrix solver to improve the stability and convergence, also TVD scheme is applied to capture a steep phase distribution accurately. Test calculations have been performed for the conditions correspond to the experiments by Gilbertson et al. and Angelini et al. in which mixing of solid particles and water were observed in iso-thermal condition and with boiling, respectively. (author).

  2. Development of steam explosion simulation code JASMINE

    International Nuclear Information System (INIS)

    Moriyama, Kiyofumi; Yamano, Norihiro; Maruyama, Yu; Kudo, Tamotsu; Sugimoto, Jun; Nagano, Katsuhiro; Araki, Kazuhiro.

    1995-11-01

    A steam explosion is considered as a phenomenon which possibly threatens the integrity of the containment vessel of a nuclear power plant in a severe accident condition. A numerical calculation code JASMINE (JAeri Simulator for Multiphase INteraction and Explosion) purposed to simulate the whole process of steam explosions has been developed. The premixing model is based on a multiphase flow simulation code MISTRAL by Fuji Research Institute Co. In JASMINE code, the constitutive equations and the flow regime map are modified for the simulation of premixing related phenomena. The numerical solution method of the original code is succeeded, i.e. the basic equations are discretized semi-implicitly, BCGSTAB method is used for the matrix solver to improve the stability and convergence, also TVD scheme is applied to capture a steep phase distribution accurately. Test calculations have been performed for the conditions correspond to the experiments by Gilbertson et al. and Angelini et al. in which mixing of solid particles and water were observed in iso-thermal condition and with boiling, respectively. (author)

  3. Code-To-Code Benchmarking Of The Porflow And GoldSim Contaminant Transport Models Using A Simple 1-D Domain - 11191

    International Nuclear Information System (INIS)

    Hiergesell, R.; Taylor, G.

    2010-01-01

    An investigation was conducted to compare and evaluate contaminant transport results of two model codes, GoldSim and Porflow, using a simple 1-D string of elements in each code. Model domains were constructed to be identical with respect to cell numbers and dimensions, matrix material, flow boundary and saturation conditions. One of the codes, GoldSim, does not simulate advective movement of water; therefore the water flux term was specified as a boundary condition. In the other code, Porflow, a steady-state flow field was computed and contaminant transport was simulated within that flow-field. The comparisons were made solely in terms of the ability of each code to perform contaminant transport. The purpose of the investigation was to establish a basis for, and to validate follow-on work that was conducted in which a 1-D GoldSim model developed by abstracting information from Porflow 2-D and 3-D unsaturated and saturated zone models and then benchmarked to produce equivalent contaminant transport results. A handful of contaminants were selected for the code-to-code comparison simulations, including a non-sorbing tracer and several long- and short-lived radionuclides exhibiting both non-sorbing to strongly-sorbing characteristics with respect to the matrix material, including several requiring the simulation of in-growth of daughter radionuclides. The same diffusion and partitioning coefficients associated with each contaminant and the half-lives associated with each radionuclide were incorporated into each model. A string of 10-elements, having identical spatial dimensions and properties, were constructed within each code. GoldSim's basic contaminant transport elements, Mixing cells, were utilized in this construction. Sand was established as the matrix material and was assigned identical properties (e.g. bulk density, porosity, saturated hydraulic conductivity) in both codes. Boundary conditions applied included an influx of water at the rate of 40 cm/yr at one

  4. Cesarean Delivery for a Life‑threatening Preterm Placental Abruption

    African Journals Online (AJOL)

    Following a failed induction of labor with a deteriorating maternal condition despite resuscitation, emergency cesarean delivery was offered with good maternal outcome. Cesarean delivery could avert further disease progression and possible maternal death in cases of severe preterm placental abruption where vaginal ...

  5. Code Package to Analyze Parameters of the WWER Fuel Rod. TOPRA-2 Code - Verification Data

    International Nuclear Information System (INIS)

    Scheglov, A.; Proselkov, V.; Passage, G.; Stefanova, S.

    2009-01-01

    Presented are the data for computer codes to analyze WWER fuel rods, used in the WWER department of RRC 'Kurchatov Institute'. Presented is the description of TOPRA-2 code intended for the engineering analysis of thermophysical and strength parameters of the WWER fuel rod - temperature distributions along the fuel radius, gas pressures under the cladding, stresses in the cladding, etc. for the reactor operation in normal conditions. Presented are some results of the code verification against test problems and the data obtained in the experimental programs. Presented are comparison results of the calculations with TOPRA-2 and TRANSURANUS (V1M1J06) codes. Results obtained in the course of verification demonstrate possibility of application of the methodology and TOPRA-2 code for the engineering analysis of the WWER fuel rods

  6. Soft-decision decoding of RS codes

    DEFF Research Database (Denmark)

    Justesen, Jørn

    2005-01-01

    By introducing a few simplifying assumptions we derive a simple condition for successful decoding using the Koetter-Vardy algorithm for soft-decision decoding of RS codes. We show that the algorithm has a significant advantage over hard decision decoding when the code rate is low, when two or more...

  7. Optimal codes as Tanner codes with cyclic component codes

    DEFF Research Database (Denmark)

    Høholdt, Tom; Pinero, Fernando; Zeng, Peng

    2014-01-01

    In this article we study a class of graph codes with cyclic code component codes as affine variety codes. Within this class of Tanner codes we find some optimal binary codes. We use a particular subgraph of the point-line incidence plane of A(2,q) as the Tanner graph, and we are able to describe ...

  8. The impact of international codes of conduct on employment ...

    African Journals Online (AJOL)

    The study examined how international codes of conduct address employment conditions and gender issues in the Chinese flower industry. A sample of 20 companies was purposively selected and 200 workers from these companies were interviewed. The adoption of international codes did not improve workers conditions ...

  9. Tidal volume delivery from ICU ventilators at BTPS conditions: a bench study.

    Science.gov (United States)

    Duchateau, Paul; Guérin, Claude

    2013-04-01

    Even though it is not a common practice, an external filter to the expiratory limb of the breathing circuit may protect the expiratory valve from water saturation in case of nebulization, or from the environment in case of lung infection with multi-drug-resistant micro-organisms or H1N1 influenza. We added an external filter to the expiratory limb and measured tidal volume (VT) from 6 ICU ventilators: 2 with built-in expiratory filter (Avea, Puritan Bennett 840), and 4 without (Engström Carestation, Evita XL, Evita V500, and Servo-i), set in volume controlled mode, at BTPS (body temperature and pressure saturated) condition, with a heated humidifier and a lung model (compliance 16 mL/cm H2O, resistance 20 cm H2O/L/s) placed inside a neonatal incubator. The temperature was targeted at 37°C for both the heated humidifier and the incubator. The setup was run continuously for 24 hours. In the latter 4 ICU ventilators, a Hygrobac or Sterivent S external filter was placed upstream from the expiratory valve for an additional 24-hour period for each. At the end of this period, VT was measured at 4 nominal VT values (300, 400, 500, and 800 mL) with a pneumotachograph. The volume error computed from the ratio of set to measured VT (% set VT) was the primary end point. In these warm and wet conditions, volume error averaged 96 ± 3% for Avea, 100 ± 7% for Puritan Bennett 840, 90 ± 2% for Evita XL, 100 ± 7% for Evita V500, 105 ± 2% for Servo-i, and 108 ± 4% for Engström Carestation (P ventilators for VT delivery, with further significant changes occurring after addition of a filter at the distal expiratory limb.

  10. Optimizing oxygenation and intubation conditions during awake fibre-optic intubation using a high-flow nasal oxygen-delivery system.

    Science.gov (United States)

    Badiger, S; John, M; Fearnley, R A; Ahmad, I

    2015-10-01

    Awake fibre-optic intubation is a widely practised technique for anticipated difficult airway management. Despite the administration of supplemental oxygen during the procedure, patients are still at risk of hypoxia because of the effects of sedation, local anaesthesia, procedural complications, and the presence of co-morbidities. Traditionally used oxygen-delivery devices are low flow, and most do not have a sufficient reservoir or allow adequate fresh gas flow to meet the patient's peak inspiratory flow rate, nor provide an adequate fractional inspired oxygen concentration to prevent desaturation should complications arise. A prospective observational study was conducted using a high-flow humidified transnasal oxygen-delivery system during awake fibre-optic intubation in 50 patients with anticipated difficult airways. There were no episodes of desaturation or hypercapnia using the high-flow system, and in all patients the oxygen saturation improved above baseline values, despite one instance of apnoea resulting from over-sedation. All patients reported a comfortable experience using the device. The high-flow nasal oxygen-delivery system improves oxygenation saturation, decreases the risk of desaturation during the procedure, and potentially, optimizes conditions for awake fibre-optic intubation. The soft nasal cannulae uniquely allow continuous oxygenation and simultaneous passage of the fibrescope and tracheal tube. The safety of the procedure may be increased, because any obstruction, hypoventilation, or periods of apnoea that may arise may be tolerated for longer, allowing more time to achieve ventilation in an optimally oxygenated patient. © The Author 2015. Published by Oxford University Press on behalf of the British Journal of Anaesthesia. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  11. A Low-Jitter Wireless Transmission Based on Buffer Management in Coding-Aware Routing

    Directory of Open Access Journals (Sweden)

    Cunbo Lu

    2015-08-01

    Full Text Available It is significant to reduce packet jitter for real-time applications in a wireless network. Existing coding-aware routing algorithms use the opportunistic network coding (ONC scheme in a packet coding algorithm. The ONC scheme never delays packets to wait for the arrival of a future coding opportunity. The loss of some potential coding opportunities may degrade the contribution of network coding to jitter performance. In addition, most of the existing coding-aware routing algorithms assume that all flows participating in the network have equal rate. This is unrealistic, since multi-rate environments often appear. To overcome the above problem and expand coding-aware routing to multi-rate scenarios, from the view of data transmission, we present a low-jitter wireless transmission algorithm based on buffer management (BLJCAR, which decides packets in coding node according to the queue-length based threshold policy instead of the regular ONC policy as used in existing coding-aware routing algorithms. BLJCAR is a unified framework to merge the single rate case and multiple rate case. Simulations results show that the BLJCAR algorithm embedded in coding-aware routing outperforms the traditional ONC policy in terms of jitter, packet delivery delay, packet loss ratio and network throughput in network congestion in any traffic rates.

  12. Maternal asthma, diabetes, and high blood pressure are associated with low birth weight and increased hospital birth and delivery charges; Hawai'i hospital discharge data 2003-2008.

    Science.gov (United States)

    Hayes, Donald K; Feigal, David W; Smith, Ruben A; Fuddy, Loretta J

    2014-02-01

    Asthma, diabetes, and high blood pressure are common maternal conditions that can impact birth outcomes. Data from hospital discharges in Hawai'i were analyzed for 107,034 singleton births from 2003-2008. Categories were determined using the International Statistical Classification of Diseases, ninth revision (ICD-9) from linked delivery records of mother and infant. Prevalence estimates of asthma (ICD-9: 493), diabetes (ICD-9: 250,648.0, 648.8), high blood pressure (ICD-9: 401-405,642) as coded on the delivery record, low birth weight (4500 grams), Cesarean delivery, and median hospital charges were calculated. Median regression analysis assessed total hospital charges adjusting for maternal age, maternal race, insurance, and Cesarean delivery. Maternal asthma was present in 4.3% (95% confidence interval=4.1-4.4%), maternal diabetes was present in 7.7% (95% CI=7.6-7.9%), and maternal high blood pressure was present in 9.2% (95% CI=9.0-9.3%) of births. In the adjusted median regression analysis, mothers with asthma had $999 (95% CI: $886 to $1,112) higher hospital charges compared to those without; mothers with diabetes had $743 (95% CI: $636 to $850) higher charges compared to those without; and mothers with high blood pressure had $2,314 (95% CI: $2,194 to $2,434) higher charges compared to those without. Asthma, diabetes, and high blood pressure are associated with higher hospital delivery charges and low birth weight. Diabetes and high blood pressure were also associated with Cesarean delivery. An increased awareness of the impact of these conditions on both adverse birth outcomes and the development of chronic disease is needed.

  13. Tristan code and its application

    Science.gov (United States)

    Nishikawa, K.-I.

    Since TRISTAN: The 3-D Electromagnetic Particle Code was introduced in 1990, it has been used for many applications including the simulations of global solar windmagnetosphere interaction. The most essential ingridients of this code have been published in the ISSS-4 book. In this abstract we describe some of issues and an application of this code for the study of global solar wind-magnetosphere interaction including a substorm study. The basic code (tristan.f) for the global simulation and a local simulation of reconnection with a Harris model (issrec2.f) are available at http:/www.physics.rutger.edu/˜kenichi. For beginners the code (isssrc2.f) with simpler boundary conditions is suitable to start to run simulations. The future of global particle simulations for a global geospace general circulation (GGCM) model with predictive capability (for Space Weather Program) is discussed.

  14. Durability of switchable QR code carriers under hydrolytic and photolytic conditions

    International Nuclear Information System (INIS)

    Ecker, Melanie; Pretsch, Thorsten

    2013-01-01

    Following a guest diffusion approach, the surface of a shape memory poly(ester urethane) (PEU) was either black or blue colored. Bowtie-shaped quick response (QR) code carriers were then obtained from laser engraving and cutting, before thermo-mechanical functionalization (programming) was applied to stabilize the PEU in a thermo-responsive (switchable) state. The stability of the dye within the polymer surface and long-term functionality of the polymer were investigated against UVA and hydrolytic ageing. Spectrophotometric investigations verified UVA ageing-related color shifts from black to yellow-brownish and blue to petrol-greenish whereas hydrolytically aged samples changed from black to greenish and blue to light blue. In the case of UVA ageing, color changes were accompanied by dye decolorization, whereas hydrolytic ageing led to contrast declines due to dye diffusion. The Michelson contrast could be identified as an effective tool to follow ageing-related contrast changes between surface-dyed and laser-ablated (undyed) polymer regions. As soon as the Michelson contrast fell below a crucial value of 0.1 due to ageing, the QR code was no longer decipherable with a scanning device. Remarkably, the PEU information carrier base material could even then be adequately fixed and recovered. Hence, the surface contrast turned out to be the decisive parameter for QR code carrier applicability. (paper)

  15. Durability of switchable QR code carriers under hydrolytic and photolytic conditions

    Science.gov (United States)

    Ecker, Melanie; Pretsch, Thorsten

    2013-09-01

    Following a guest diffusion approach, the surface of a shape memory poly(ester urethane) (PEU) was either black or blue colored. Bowtie-shaped quick response (QR) code carriers were then obtained from laser engraving and cutting, before thermo-mechanical functionalization (programming) was applied to stabilize the PEU in a thermo-responsive (switchable) state. The stability of the dye within the polymer surface and long-term functionality of the polymer were investigated against UVA and hydrolytic ageing. Spectrophotometric investigations verified UVA ageing-related color shifts from black to yellow-brownish and blue to petrol-greenish whereas hydrolytically aged samples changed from black to greenish and blue to light blue. In the case of UVA ageing, color changes were accompanied by dye decolorization, whereas hydrolytic ageing led to contrast declines due to dye diffusion. The Michelson contrast could be identified as an effective tool to follow ageing-related contrast changes between surface-dyed and laser-ablated (undyed) polymer regions. As soon as the Michelson contrast fell below a crucial value of 0.1 due to ageing, the QR code was no longer decipherable with a scanning device. Remarkably, the PEU information carrier base material could even then be adequately fixed and recovered. Hence, the surface contrast turned out to be the decisive parameter for QR code carrier applicability.

  16. Recalculating the steady state conditions of the V-1000 zero-power facility at Kurchatov Institute using Monte Carlo and nodal diffusion codes

    Energy Technology Data Exchange (ETDEWEB)

    Sahlberg, Ville [VTT Technical Research Centre of Finland Ltd, VTT (Finland)

    2017-09-15

    Continuous-energy Monte Carlo reactor physics code Serpent 2 was used to model the critical steady state conditions measured in V-1000 zero-power critical facility at Kurchatov Institute (KI), Moscow in 1990-1992. The Serpent 2 results were compared to measurements and Serpent 2 was used to generate group constants for reactor dynamics code HEXTRAN. The results of a HEXTRAN calculation of the steady state were compared to Serpent 2. The relative power density distribution of the SERPENT2 calculations compared with the measurements was within the statistical accuracy. The comparison of HEXTRAN and Serpent 2 node-wise relative power density distributions showed an accuracy of ±10%.

  17. Bilayer Protograph Codes for Half-Duplex Relay Channels

    Science.gov (United States)

    Divsalar, Dariush; VanNguyen, Thuy; Nosratinia, Aria

    2013-01-01

    Direct to Earth return links are limited by the size and power of lander devices. A standard alternative is provided by a two-hops return link: a proximity link (from lander to orbiter relay) and a deep-space link (from orbiter relay to Earth). Although direct to Earth return links are limited by the size and power of lander devices, using an additional link and a proposed coding for relay channels, one can obtain a more reliable signal. Although significant progress has been made in the relay coding problem, existing codes must be painstakingly optimized to match to a single set of channel conditions, many of them do not offer easy encoding, and most of them do not have structured design. A high-performing LDPC (low-density parity-check) code for the relay channel addresses simultaneously two important issues: a code structure that allows low encoding complexity, and a flexible rate-compatible code that allows matching to various channel conditions. Most of the previous high-performance LDPC codes for the relay channel are tightly optimized for a given channel quality, and are not easily adapted without extensive re-optimization for various channel conditions. This code for the relay channel combines structured design and easy encoding with rate compatibility to allow adaptation to the three links involved in the relay channel, and furthermore offers very good performance. The proposed code is constructed by synthesizing a bilayer structure with a pro to graph. In addition to the contribution to relay encoding, an improved family of protograph codes was produced for the point-to-point AWGN (additive white Gaussian noise) channel whose high-rate members enjoy thresholds that are within 0.07 dB of capacity. These LDPC relay codes address three important issues in an integrative manner: low encoding complexity, modular structure allowing for easy design, and rate compatibility so that the code can be easily matched to a variety of channel conditions without extensive

  18. Extension of the code COCOSYS to a dispersion code for smoke and carbon monoxide

    International Nuclear Information System (INIS)

    Sdouz, Gert; Mayrhofer, Robert

    2009-01-01

    The code COCOSYS (Containment Code SYStem) was developed by GRS in Germany to simulate processes and nuclear plant states during severe accidents in the containments of light water reactors. It contains several physical models, especially a module for aerosol behaviour. The goal of this work was to extend COCOSYS for applications in more general geometries mainly for complex public buildings. For the application in public buildings models for air condition systems and different boundary conditions according to different environments were developed. The principal application of the extended code COCOSYS is in the area of emergency situations especially in the simulation for carbon monoxide and smoke dispersion. After developing and implementing the new models several test calculations were performed to evaluate the functionality of the extended code. The comparison of the results with those of the original COCOSYS code showed no discrepancies. For the first realistic application several fire emergency scenarios in the Vienna General Hospital (AKH) were selected in agreement with the fire department of the hospital. One of the scenarios addresses the danger of carbon monoxide (CO) and smoke leaking into a fire protection section through a damaged fire protection flap. As a result of the dispersion simulation the CO-concentration in all of the rooms is obtained. Together with additional results as deposition and smoke dispersion the outcome of the simulation can be used for training. Among the next steps are the validation of the new models and the selection of critical scenarios. (author)

  19. Maternal Asthma, Diabetes, and High Blood Pressure are Associated with Low Birth Weight and Increased Hospital Birth and Delivery Charges; Hawai‘i Hospital Discharge Data 2003–2008

    Science.gov (United States)

    Feigal, David W; Smith, Ruben A; Fuddy, Loretta J

    2014-01-01

    Asthma, diabetes, and high blood pressure are common maternal conditions that can impact birth outcomes. Data from hospital discharges in Hawai‘i were analyzed for 107,034 singleton births from 2003–2008. Categories were determined using the International Statistical Classification of Diseases, ninth revision (ICD-9) from linked delivery records of mother and infant. Prevalence estimates of asthma (ICD-9: 493), diabetes (ICD-9: 250,648.0, 648.8), high blood pressure (ICD-9: 401–405,642) as coded on the delivery record, low birth weight (4500 grams), Cesarean delivery, and median hospital charges were calculated. Median regression analysis assessed total hospital charges adjusting for maternal age, maternal race, insurance, and Cesarean delivery. Maternal asthma was present in 4.3% (95% confidence interval=4.1–4.4%), maternal diabetes was present in 7.7% (95% CI=7.6–7.9%), and maternal high blood pressure was present in 9.2% (95% CI=9.0–9.3%) of births. In the adjusted median regression analysis, mothers with asthma had $999 (95% CI: $886 to $1,112) higher hospital charges compared to those without; mothers with diabetes had $743 (95% CI: $636 to $850) higher charges compared to those without; and mothers with high blood pressure had $2,314 (95% CI: $2,194 to $2,434) higher charges compared to those without. Asthma, diabetes, and high blood pressure are associated with higher hospital delivery charges and low birth weight. Diabetes and high blood pressure were also associated with Cesarean delivery. An increased awareness of the impact of these conditions on both adverse birth outcomes and the development of chronic disease is needed. PMID:24567868

  20. Assessment of the computer code COBRA/CFTL

    International Nuclear Information System (INIS)

    Baxi, C.B.; Burhop, C.J.

    1981-07-01

    The COBRA/CFTL code has been developed by Oak Ridge National Laboratory (ORNL) for thermal-hydraulic analysis of simulated gas-cooled fast breeder reactor (GCFR) core assemblies to be tested in the core flow test loop (CFTL). The COBRA/CFTL code was obtained by modifying the General Atomic code COBRA*GCFR. This report discusses these modifications, compares the two code results for three cases which represent conditions from fully rough turbulent flow to laminar flow. Case 1 represented fully rough turbulent flow in the bundle. Cases 2 and 3 represented laminar and transition flow regimes. The required input for the COBRA/CFTL code, a sample problem input/output and the code listing are included in the Appendices

  1. Protein-Based Drug-Delivery Materials

    Directory of Open Access Journals (Sweden)

    Dave Jao

    2017-05-01

    Full Text Available There is a pressing need for long-term, controlled drug release for sustained treatment of chronic or persistent medical conditions and diseases. Guided drug delivery is difficult because therapeutic compounds need to survive numerous transport barriers and binding targets throughout the body. Nanoscale protein-based polymers are increasingly used for drug and vaccine delivery to cross these biological barriers and through blood circulation to their molecular site of action. Protein-based polymers compared to synthetic polymers have the advantages of good biocompatibility, biodegradability, environmental sustainability, cost effectiveness and availability. This review addresses the sources of protein-based polymers, compares the similarity and differences, and highlights characteristic properties and functionality of these protein materials for sustained and controlled drug release. Targeted drug delivery using highly functional multicomponent protein composites to guide active drugs to the site of interest will also be discussed. A systematical elucidation of drug-delivery efficiency in the case of molecular weight, particle size, shape, morphology, and porosity of materials will then be demonstrated to achieve increased drug absorption. Finally, several important biomedical applications of protein-based materials with drug-delivery function—including bone healing, antibiotic release, wound healing, and corneal regeneration, as well as diabetes, neuroinflammation and cancer treatments—are summarized at the end of this review.

  2. Community household income and resource utilization for common inpatient pediatric conditions.

    Science.gov (United States)

    Fieldston, Evan S; Zaniletti, Isabella; Hall, Matthew; Colvin, Jeffrey D; Gottlieb, Laura; Macy, Michelle L; Alpern, Elizabeth R; Morse, Rustin B; Hain, Paul D; Sills, Marion R; Frank, Gary; Shah, Samir S

    2013-12-01

    Child health is influenced by biomedical and socioeconomic factors. Few studies have explored the relationship between community-level income and inpatient resource utilization for children. Our objective was to analyze inpatient costs for children hospitalized with common conditions in relation to zip code-based median annual household income (HHI). Retrospective national cohort from 32 freestanding children's hospitals for asthma, diabetes, bronchiolitis and respiratory syncytial virus, pneumonia, and kidney and urinary tract infections. Standardized cost of care for individual hospitalizations and across hospitalizations for the same patient and condition were modeled by using mixed-effects methods, adjusting for severity of illness, age, gender, and race. Main exposure was median annual HHI. Posthoc tests compared adjusted standardized costs for patients from the lowest and highest income groups. From 116,636 hospitalizations, 4 of 5 conditions had differences at the hospitalization and at the patient level, with lowest-income groups having higher costs. The individual hospitalization level cost differences ranged from $187 (4.1%) to $404 (6.4%). Patient-level cost differences ranged from $310 to $1087 or 6.5% to 15% higher for the lowest-income patients. Higher costs were typically not for laboratory, imaging, or pharmacy costs. In total, patients from lowest income zip codes had $8.4 million more in hospitalization-level costs and $13.6 million more in patient-level costs. Lower community-level HHI is associated with higher inpatient costs of care for 4 of 5 common pediatric conditions. These findings highlight the need to consider socioeconomic status in health care system design, delivery, and reimbursement calculations.

  3. Mathematical model and computer code for coated particles performance at normal operating conditions

    International Nuclear Information System (INIS)

    Golubev, I.; Kadarmetov, I.; Makarov, V.

    2002-01-01

    Computer modeling of thermo-mechanical behavior of coated particles during operating both at normal and off-normal conditions has a very significant role particularly on a stage of new reactors development. In Russia a big experience has been accumulated on fabrication and reactor tests of CP and fuel elements with UO 2 kernels. However, this experience cannot be using in full volume for development of a new reactor installation GT-MHR. This is due to very deep burn-up of the fuel based on plutonium oxide (up to 70% fima). Therefore the mathematical modeling of CP thermal-mechanical behavior and failure prediction becomes particularly important. The authors have a clean understanding that serviceability of fuel with high burn-ups are defined not only by thermo-mechanics, but also by structured changes in coating materials, thermodynamics of chemical processes, 'amoeba-effect', formation CO etc. In the report the first steps of development of integrate code for numerical modeling of coated particles behavior and some calculating results concerning the influence of various design parameters on fuel coated particles endurance for GT-MHR normal operating conditions are submitted. A failure model is developed to predict the fraction of TRISO-coated particles. In this model it is assumed that the failure of CP depends not only on probability of SiC-layer fracture but also on the PyC-layers damage. The coated particle is considered as a uniform design. (author)

  4. TACO: a finite element heat transfer code

    International Nuclear Information System (INIS)

    Mason, W.E. Jr.

    1980-02-01

    TACO is a two-dimensional implicit finite element code for heat transfer analysis. It can perform both linear and nonlinear analyses and can be used to solve either transient or steady state problems. Either plane or axisymmetric geometries can be analyzed. TACO has the capability to handle time or temperature dependent material properties and materials may be either isotropic or orthotropic. A variety of time and temperature dependent loadings and boundary conditions are available including temperature, flux, convection, and radiation boundary conditions and internal heat generation. Additionally, TACO has some specialized features such as internal surface conditions (e.g., contact resistance), bulk nodes, enclosure radiation with view factor calculations, and chemical reactive kinetics. A user subprogram feature allows for any type of functional representation of any independent variable. A bandwidth and profile minimization option is also available in the code. Graphical representation of data generated by TACO is provided by a companion post-processor named POSTACO. The theory on which TACO is based is outlined, the capabilities of the code are explained, the input data required to perform an analysis with TACO are described. Some simple examples are provided to illustrate the use of the code

  5. A proposed metamodel for the implementation of object oriented software through the automatic generation of source code

    Directory of Open Access Journals (Sweden)

    CARVALHO, J. S. C.

    2008-12-01

    Full Text Available During the development of software one of the most visible risks and perhaps the biggest implementation obstacle relates to the time management. All delivery deadlines software versions must be followed, but it is not always possible, sometimes due to delay in coding. This paper presents a metamodel for software implementation, which will rise to a development tool for automatic generation of source code, in order to make any development pattern transparent to the programmer, significantly reducing the time spent in coding artifacts that make up the software.

  6. Volunteer Delivery of a Community-Based Strength Training Program: Comparison of Adopting and Nonadopting Extension Educator Perspectives

    Directory of Open Access Journals (Sweden)

    Lisa T. Washburn

    2016-10-01

    Full Text Available Volunteer leaders are increasingly being utilized to deliver community strength training classes, but the factors affecting adoption of volunteer delivery approaches by educators or program managers have not been well explored. This study sought to identify these factors by comparing perspectives of adopting and nonadopting county Extension educators for a group strength training program delivered through county Cooperative Extension offices. Semistructured interviews were conducted with a purposive sample of adopting (n=6 and nonadopting (n=13 educators. Interviews were recorded, transcribed verbatim, and coded using thematic content analysis. Review of codes related to adoption or nonadoption of volunteer delivery approaches produced common themes. Both groups acknowledged role differences between educators and volunteers and expressed concerns about maintaining program quality. Adopters expressed greater comfort with volunteer-led program approaches and understanding of the educator-volunteer role. Nonadopters were hesitant to request program participants serve as leaders but felt participants were capable. Both groups were motivated to offer the program for dual personal and community benefit, but nonadopters expressed reliance on the program to maintain physical activity habits and for social support. Findings can inform others seeking to adapt community programs for volunteer delivery or engage volunteers in existing program delivery.

  7. Basic Pilot Code Development for Two-Fluid, Three-Field Model

    International Nuclear Information System (INIS)

    Jeong, Jae Jun; Bae, S. W.; Lee, Y. J.; Chung, B. D.; Hwang, M.; Ha, K. S.; Kang, D. H.

    2006-03-01

    A basic pilot code for one-dimensional, transient, two-fluid, three-field model has been developed. Using 9 conceptual problems, the basic pilot code has been verified. The results of the verification are summarized below: - It was confirmed that the basic pilot code can simulate various flow conditions (such as single-phase liquid flow, bubbly flow, slug/churn turbulent flow, annular-mist flow, and single-phase vapor flow) and transitions of the flow conditions. A mist flow was not simulated, but it seems that the basic pilot code can simulate mist flow conditions. - The pilot code was programmed so that the source terms of the governing equations and numerical solution schemes can be easily tested. - The mass and energy conservation was confirmed for single-phase liquid and single-phase vapor flows. - It was confirmed that the inlet pressure and velocity boundary conditions work properly. - It was confirmed that, for single- and two-phase flows, the velocity and temperature of non-existing phase are calculated as intended. - During the simulation of a two-phase flow, the calculation reaches a quasisteady state with small-amplitude oscillations. The oscillations seem to be induced by some numerical causes. The research items for the improvement of the basic pilot code are listed in the last section of this report

  8. Basic Pilot Code Development for Two-Fluid, Three-Field Model

    Energy Technology Data Exchange (ETDEWEB)

    Jeong, Jae Jun; Bae, S. W.; Lee, Y. J.; Chung, B. D.; Hwang, M.; Ha, K. S.; Kang, D. H

    2006-03-15

    A basic pilot code for one-dimensional, transient, two-fluid, three-field model has been developed. Using 9 conceptual problems, the basic pilot code has been verified. The results of the verification are summarized below: - It was confirmed that the basic pilot code can simulate various flow conditions (such as single-phase liquid flow, bubbly flow, slug/churn turbulent flow, annular-mist flow, and single-phase vapor flow) and transitions of the flow conditions. A mist flow was not simulated, but it seems that the basic pilot code can simulate mist flow conditions. - The pilot code was programmed so that the source terms of the governing equations and numerical solution schemes can be easily tested. - The mass and energy conservation was confirmed for single-phase liquid and single-phase vapor flows. - It was confirmed that the inlet pressure and velocity boundary conditions work properly. - It was confirmed that, for single- and two-phase flows, the velocity and temperature of non-existing phase are calculated as intended. - During the simulation of a two-phase flow, the calculation reaches a quasisteady state with small-amplitude oscillations. The oscillations seem to be induced by some numerical causes. The research items for the improvement of the basic pilot code are listed in the last section of this report.

  9. Time trends in births and cesarean deliveries among women with disabilities.

    Science.gov (United States)

    Horner-Johnson, Willi; Biel, Frances M; Darney, Blair G; Caughey, Aaron B

    2017-07-01

    Although it is likely that childbearing among women with disabilities is increasing, no empirical data have been published on changes over time in the numbers of women with disabilities giving birth. Further, while it is known that women with disabilities are at increased risk of cesarean delivery, temporal trends in cesarean deliveries among women with disabilities have not been examined. To assess time trends in births by any mode and in primary cesarean deliveries among women with physical, sensory, or intellectual/developmental disabilities. We conducted a retrospective cohort study using linked vital records and hospital discharge data from all deliveries in California, 2000-2010 (n = 4,605,061). We identified women with potential disabilities using ICD-9 codes. We used descriptive statistics and visualizations to examine time patterns. Logistic regression analyses assessed the association between disability and primary cesarean delivery, stratified by year. Among all women giving birth, the proportion with a disability increased from 0.27% in 2000 to 0.80% in 2010. Women with disabilities had significantly elevated odds of primary cesarean delivery in each year, but the magnitude of the odds ratio decreased over time from 2.60 (95% CI = 2.25 = 2.99) in 2000 to 1.66 (95% CI = 1.51-1.81) in 2010. Adequate clinician training is needed to address the perinatal care needs of the increasing numbers of women with disabilities giving birth. Continued efforts to understand cesarean delivery patterns and reasons for cesarean deliveries may help guide further reductions in proportions of cesarean deliveries among women with disabilities relative to women without disabilities. Copyright © 2017 Elsevier Inc. All rights reserved.

  10. NALAP: an LMFBR system transient code

    International Nuclear Information System (INIS)

    Martin, B.A.; Agrawal, A.K.; Albright, D.C.; Epel, L.G.; Maise, G.

    1975-07-01

    NALAP is a LMFBR system transient code. This code, adapted from the light water reactor transient code RELAP 3B, simulates thermal-hydraulic response of sodium cooled fast breeder reactors when subjected to postulated accidents such as a massive pipe break as well as a variety of other upset conditions that do not disrupt the system geometry. Various components of the plant are represented by control volumes. These control volumes are connected by junctions some of which may be leak or fill junctions. The fluid flow equations are modeled as compressible, single-stream flow with momentum flux in one dimension. The transient response is computed by integrating the thermal-hydraulic conservation equations from user-initialized operating conditions by an implicit numerical scheme. Point kinetics approximation is used to represent the time dependent heat generation in the reactor core

  11. Error analysis of supercritical water correlations using ATHLET system code under DHT conditions

    Energy Technology Data Exchange (ETDEWEB)

    Samuel, J., E-mail: jeffrey.samuel@uoit.ca [Univ. of Ontario Inst. of Tech., Oshawa, ON (Canada)

    2014-07-01

    The thermal-hydraulic computer code ATHLET (Analysis of THermal-hydraulics of LEaks and Transients) is used for analysis of anticipated and abnormal plant transients, including safety analysis of Light Water Reactors (LWRs) and Russian Graphite-Moderated High Power Channel-type Reactors (RBMKs). The range of applicability of ATHLET has been extended to supercritical water by updating the fluid-and transport-properties packages, thus enabling the code to the used in analysis of SuperCritical Water-cooled Reactors (SCWRs). Several well-known heat-transfer correlations for supercritical fluids were added to the ATHLET code and a numerical model was created to represent an experimental test section. In this work, the error in the Heat Transfer Coefficient (HTC) calculation by the ATHLET model is studied along with the ability of the various correlations to predict different heat transfer regimes. (author)

  12. Lossy/lossless coding of bi-level images

    DEFF Research Database (Denmark)

    Martins, Bo; Forchhammer, Søren

    1997-01-01

    Summary form only given. We present improvements to a general type of lossless, lossy, and refinement coding of bi-level images (Martins and Forchhammer, 1996). Loss is introduced by flipping pixels. The pixels are coded using arithmetic coding of conditional probabilities obtained using a template...... as is known from JBIG and proposed in JBIG-2 (Martins and Forchhammer). Our new state-of-the-art results are obtained using the more general free tree instead of a template. Also we introduce multiple refinement template coding. The lossy algorithm is analogous to the greedy `rate...

  13. A user input manual for single fuel rod behaviour analysis code FEMAXI-III

    International Nuclear Information System (INIS)

    Saito, Hiroaki; Yanagisawa, Kazuaki; Fujita, Misao.

    1983-03-01

    Principal objectives of Safety related research in connection with lighr water reactor fuel rods under normal operating condition are mainly addressed 1) to assess fuel integrity under steady state condition and 2) to generate initial condition under hypothetical accident. These assessments have to be relied principally upon steady state fuel behaviour computing code that is able to calculate fuel conditions to tbe occurred in a various manner. To achieve these objectives, efforts have been made to develope analytical computer code that calculates in-reactor fuel rod behaviour in best estimate manner. The computer code developed for the prediction of the long-term burnup response of single fuel rod under light water reactor condition is the third in a series of code versions:FEMAMI-III. The code calculates temperature, rod internal gas pressure, fission gas release and pellet-cladding interaction related rod deformation as a function of time-dependent fuel rod power and coolant boundary conditions. This document serves as a user input manual for the code FEMAMI-III which has opened to the public in year of 1982. A general description of the code input and output are included together with typical examples of input data. A detailed description of structures, analytical submodels and solution schemes in the code shall be given in the separate document to be published. (author)

  14. Subchannel analysis code development for CANDU fuel channel

    International Nuclear Information System (INIS)

    Park, J. H.; Suk, H. C.; Jun, J. S.; Oh, D. J.; Hwang, D. H.; Yoo, Y. J.

    1998-07-01

    Since there are several subchannel codes such as COBRA and TORC codes for a PWR fuel channel but not for a CANDU fuel channel in our country, the subchannel analysis code for a CANDU fuel channel was developed for the prediction of flow conditions on the subchannels, for the accurate assessment of the thermal margin, the effect of appendages, and radial/axial power profile of fuel bundles on flow conditions and CHF and so on. In order to develop the subchannel analysis code for a CANDU fuel channel, subchannel analysis methodology and its applicability/pertinence for a fuel channel were reviewed from the CANDU fuel channel point of view. Several thermalhydraulic and numerical models for the subchannel analysis on a CANDU fuel channel were developed. The experimental data of the CANDU fuel channel were collected, analyzed and used for validation of a subchannel analysis code developed in this work. (author). 11 refs., 3 tabs., 50 figs

  15. SU-E-T-254: Optimization of GATE and PHITS Monte Carlo Code Parameters for Uniform Scanning Proton Beam Based On Simulation with FLUKA General-Purpose Code

    Energy Technology Data Exchange (ETDEWEB)

    Kurosu, K [Department of Radiation Oncology, Osaka University Graduate School of Medicine, Osaka (Japan); Department of Medical Physics ' Engineering, Osaka University Graduate School of Medicine, Osaka (Japan); Takashina, M; Koizumi, M [Department of Medical Physics ' Engineering, Osaka University Graduate School of Medicine, Osaka (Japan); Das, I; Moskvin, V [Department of Radiation Oncology, Indiana University School of Medicine, Indianapolis, IN (United States)

    2014-06-01

    Purpose: Monte Carlo codes are becoming important tools for proton beam dosimetry. However, the relationships between the customizing parameters and percentage depth dose (PDD) of GATE and PHITS codes have not been reported which are studied for PDD and proton range compared to the FLUKA code and the experimental data. Methods: The beam delivery system of the Indiana University Health Proton Therapy Center was modeled for the uniform scanning beam in FLUKA and transferred identically into GATE and PHITS. This computational model was built from the blue print and validated with the commissioning data. Three parameters evaluated are the maximum step size, cut off energy and physical and transport model. The dependence of the PDDs on the customizing parameters was compared with the published results of previous studies. Results: The optimal parameters for the simulation of the whole beam delivery system were defined by referring to the calculation results obtained with each parameter. Although the PDDs from FLUKA and the experimental data show a good agreement, those of GATE and PHITS obtained with our optimal parameters show a minor discrepancy. The measured proton range R90 was 269.37 mm, compared to the calculated range of 269.63 mm, 268.96 mm, and 270.85 mm with FLUKA, GATE and PHITS, respectively. Conclusion: We evaluated the dependence of the results for PDDs obtained with GATE and PHITS Monte Carlo generalpurpose codes on the customizing parameters by using the whole computational model of the treatment nozzle. The optimal parameters for the simulation were then defined by referring to the calculation results. The physical model, particle transport mechanics and the different geometrybased descriptions need accurate customization in three simulation codes to agree with experimental data for artifact-free Monte Carlo simulation. This study was supported by Grants-in Aid for Cancer Research (H22-3rd Term Cancer Control-General-043) from the Ministry of Health

  16. Implementation and Analysis Audio Steganography Used Parity Coding for Symmetric Cryptography Key Delivery

    Directory of Open Access Journals (Sweden)

    Afany Zeinata Firdaus

    2013-12-01

    Full Text Available In today's era of communication, online data transactions is increasing. Various information even more accessible, both upload and download. Because it takes a capable security system. Blowfish cryptographic equipped with Audio Steganography is one way to secure the data so that the data can not be accessed by unauthorized parties. In this study Audio Steganography technique is implemented using parity coding method that is used to send the key cryptography blowfish in e-commerce applications based on Android. The results obtained for the average computation time on stage insertion (embedding the secret message is shorter than the average computation time making phase (extracting the secret message. From the test results can also be seen that the more the number of characters pasted the greater the noise received, where the highest SNR is obtained when a character is inserted as many as 506 characters is equal to 11.9905 dB, while the lowest SNR obtained when a character is inserted as many as 2006 characters at 5,6897 dB . Keywords: audio steganograph, parity coding, embedding, extractin, cryptography blowfih.

  17. CACTI: free, open-source software for the sequential coding of behavioral interactions.

    Science.gov (United States)

    Glynn, Lisa H; Hallgren, Kevin A; Houck, Jon M; Moyers, Theresa B

    2012-01-01

    The sequential analysis of client and clinician speech in psychotherapy sessions can help to identify and characterize potential mechanisms of treatment and behavior change. Previous studies required coding systems that were time-consuming, expensive, and error-prone. Existing software can be expensive and inflexible, and furthermore, no single package allows for pre-parsing, sequential coding, and assignment of global ratings. We developed a free, open-source, and adaptable program to meet these needs: The CASAA Application for Coding Treatment Interactions (CACTI). Without transcripts, CACTI facilitates the real-time sequential coding of behavioral interactions using WAV-format audio files. Most elements of the interface are user-modifiable through a simple XML file, and can be further adapted using Java through the terms of the GNU Public License. Coding with this software yields interrater reliabilities comparable to previous methods, but at greatly reduced time and expense. CACTI is a flexible research tool that can simplify psychotherapy process research, and has the potential to contribute to the improvement of treatment content and delivery.

  18. Context quantization by minimum adaptive code length

    DEFF Research Database (Denmark)

    Forchhammer, Søren; Wu, Xiaolin

    2007-01-01

    Context quantization is a technique to deal with the issue of context dilution in high-order conditional entropy coding. We investigate the problem of context quantizer design under the criterion of minimum adaptive code length. A property of such context quantizers is derived for binary symbols....

  19. Locality-preserving logical operators in topological stabilizer codes

    Science.gov (United States)

    Webster, Paul; Bartlett, Stephen D.

    2018-01-01

    Locality-preserving logical operators in topological codes are naturally fault tolerant, since they preserve the correctability of local errors. Using a correspondence between such operators and gapped domain walls, we describe a procedure for finding all locality-preserving logical operators admitted by a large and important class of topological stabilizer codes. In particular, we focus on those equivalent to a stack of a finite number of surface codes of any spatial dimension, where our procedure fully specifies the group of locality-preserving logical operators. We also present examples of how our procedure applies to codes with different boundary conditions, including color codes and toric codes, as well as more general codes such as Abelian quantum double models and codes with fermionic excitations in more than two dimensions.

  20. IRSN Code of Ethics and Professional Conduct. Annex VII [TSO Mission Statement and Code of Ethics

    International Nuclear Information System (INIS)

    2018-01-01

    IRSN has adopted, in 2013, a Code of Ethics and Professional Conduct, the contents of which are summarized. As a preamble, it is indicated that the Code, which was adopted in 2013 by the Ethics Commission of IRSN and the Board of IRSN, complies with relevant constitutional and legal requirements. The introduction to the Code presents the role and missions of IRSN in the French system, as well as the various conditions and constraints that frame its action, in particular with respect to ethical issues. It states that the Code sets principles and establishes guidance for addressing these constraints and resolving conflicts that may arise, thus constituting references for the Institute and its staff, and helping IRSN’s partners in their interaction with the Institute. The stipulations of the Code are organized in four articles, reproduced and translated.

  1. Fission gas release behavior of MOX fuels under simulated daily-load-follow operation condition. IFA-554/555 test evaluation with FASTGRASS code

    International Nuclear Information System (INIS)

    Ikusawa, Yoshihisa; Ozawa, Takayuki

    2008-03-01

    IFA-554/555 load-follow tests were performed in HALDEN reactor (HBWR) to study the MOX fuel behavior under the daily-load-follow operation condition in the framework of ATR-MOX fuel development in JAEA. IFA-554/555 rig had the instruments of rod inner pressure, fuel center temperature, fuel stack elongation, and cladding elongation. Although the daily-load-follow operation in nuclear power plant is one of the available options for economical improvement, the power change in a short period in this operation causes the change of thermal and mechanical irradiation conditions. In this report, FP gas release behavior of MOX fuel rod was evaluated under the daily-load-follow operation condition with the examination data from IFA-554/555 by using the computation code 'FASTGRASS'. From the computation results of FASTGRASS code which could compute the FP gas release behavior under the transient condition, it could be concluded that FP gas was released due to the relaxation of fuel pellet inner stress and pellet temperature increase, which were caused by the cyclic power change during the daily-load-follow operation. In addition, since the amount of released FP gas decreased during the steady operation after the daily-load-follow, it could be mentioned that the total of FP gas release at the end of life with the daily-load-follow is not so much different from that without the daily-load-follow. (author)

  2. Tree Coding of Bilevel Images

    DEFF Research Database (Denmark)

    Martins, Bo; Forchhammer, Søren

    1998-01-01

    Presently, sequential tree coders are the best general purpose bilevel image coders and the best coders of halftoned images. The current ISO standard, Joint Bilevel Image Experts Group (JBIG), is a good example. A sequential tree coder encodes the data by feeding estimates of conditional...... is one order of magnitude slower than JBIG, obtains excellent and highly robust compression performance. A multipass free tree coding scheme produces superior compression results for all test images. A multipass free template coding scheme produces significantly better results than JBIG for difficult...... images such as halftones. By utilizing randomized subsampling in the template selection, the speed becomes acceptable for practical image coding...

  3. Development and Application of Subchannel Analysis Code Technology for Advanced Reactor Systems

    International Nuclear Information System (INIS)

    Hwang, Dae Hyun; Seo, K. W.

    2006-01-01

    A study has been performed for the development and assessment of a subchannel analysis code which is purposed to be used for the analysis of advanced reactor conditions with various configurations of reactor core and several kinds of reactor coolant fluids. The subchannel analysis code was developed on the basis of MATRA code which is being developed at KAERI. A GUI (Graphic User Interface) system was adopted in order to reduce input error and to enhance user convenience. The subchannel code was complemented in the property calculation modules by including various fluids such as heavy liquid metal, gas, refrigerant,and supercritical water. The subchannel code was applied to calculate the local thermal hydraulic conditions inside the non-square test bundles which was employed for the analysis of CHF. The applicability of the subchannel code was evaluated for a high temperature gas cooled reactor condition and supercritical pressure conditions with water and Freon. A subchannel analysis has been conducted for European ADS(Accelerator-Driven subcritical System) with Pb-Bi coolant through the international cooperation work between KAERI and FZK, Germany. In addition, the prediction capability of the subchannel code was evaluated for the subchannel void distribution data by participating an international code benchmark program which was organized by OECD/NRC

  4. Development and Application of Subchannel Analysis Code Technology for Advanced Reactor Systems

    Energy Technology Data Exchange (ETDEWEB)

    Hwang, Dae Hyun; Seo, K. W

    2006-01-15

    A study has been performed for the development and assessment of a subchannel analysis code which is purposed to be used for the analysis of advanced reactor conditions with various configurations of reactor core and several kinds of reactor coolant fluids. The subchannel analysis code was developed on the basis of MATRA code which is being developed at KAERI. A GUI (Graphic User Interface) system was adopted in order to reduce input error and to enhance user convenience. The subchannel code was complemented in the property calculation modules by including various fluids such as heavy liquid metal, gas, refrigerant,and supercritical water. The subchannel code was applied to calculate the local thermal hydraulic conditions inside the non-square test bundles which was employed for the analysis of CHF. The applicability of the subchannel code was evaluated for a high temperature gas cooled reactor condition and supercritical pressure conditions with water and Freon. A subchannel analysis has been conducted for European ADS(Accelerator-Driven subcritical System) with Pb-Bi coolant through the international cooperation work between KAERI and FZK, Germany. In addition, the prediction capability of the subchannel code was evaluated for the subchannel void distribution data by participating an international code benchmark program which was organized by OECD/NRC.

  5. The Aster code

    International Nuclear Information System (INIS)

    Delbecq, J.M.

    1999-01-01

    The Aster code is a 2D or 3D finite-element calculation code for structures developed by the R and D direction of Electricite de France (EdF). This dossier presents a complete overview of the characteristics and uses of the Aster code: introduction of version 4; the context of Aster (organisation of the code development, versions, systems and interfaces, development tools, quality assurance, independent validation); static mechanics (linear thermo-elasticity, Euler buckling, cables, Zarka-Casier method); non-linear mechanics (materials behaviour, big deformations, specific loads, unloading and loss of load proportionality indicators, global algorithm, contact and friction); rupture mechanics (G energy restitution level, restitution level in thermo-elasto-plasticity, 3D local energy restitution level, KI and KII stress intensity factors, calculation of limit loads for structures), specific treatments (fatigue, rupture, wear, error estimation); meshes and models (mesh generation, modeling, loads and boundary conditions, links between different modeling processes, resolution of linear systems, display of results etc..); vibration mechanics (modal and harmonic analysis, dynamics with shocks, direct transient dynamics, seismic analysis and aleatory dynamics, non-linear dynamics, dynamical sub-structuring); fluid-structure interactions (internal acoustics, mass, rigidity and damping); linear and non-linear thermal analysis; steels and metal industry (structure transformations); coupled problems (internal chaining, internal thermo-hydro-mechanical coupling, chaining with other codes); products and services. (J.S.)

  6. Calculation of accurate albedo boundary conditions for three-dimensional nodal diffusion codes by the method of characteristics

    International Nuclear Information System (INIS)

    Petkov, Petko T.

    2000-01-01

    Most of the few-group three-dimensional nodal diffusion codes used for neutronics calculations of the WWER reactors use albedo type boundary conditions on the core-reflector boundary. The conventional albedo are group-to-group reflection probabilities, defined on each outer node face. The method of characteristics is used to calculate accurate albedo by the following procedure. A many-group two-dimensional heterogeneous core-reflector problem, including a sufficient part of the core and detailed description of the adjacent reflector, is solved first. From this solution the angular flux on the core-reflector boundary is calculated in all groups for all traced neutron directions. Accurate boundary conditions can be calculated for the radial, top and bottom reflectors as well as for the absorber part of the WWER-440 reactor control assemblies. The algorithm can be used to estimate also albedo, coupling outer node faces on the radial reflector in the axial direction. Numerical results for the WWER-440 reactor are presented. (Authors)

  7. The MELTSPREAD Code for Modeling of Ex-Vessel Core Debris Spreading Behavior, Code Manual – Version3-beta

    Energy Technology Data Exchange (ETDEWEB)

    Farmer, M. T. [Argonne National Lab. (ANL), Argonne, IL (United States)

    2017-09-01

    MELTSPREAD3 is a transient one-dimensional computer code that has been developed to predict the gravity-driven flow and freezing behavior of molten reactor core materials (corium) in containment geometries. Predictions can be made for corium flowing across surfaces under either dry or wet cavity conditions. The spreading surfaces that can be selected are steel, concrete, a user-specified material (e.g., a ceramic), or an arbitrary combination thereof. The corium can have a wide range of compositions of reactor core materials that includes distinct oxide phases (predominantly Zr, and steel oxides) plus metallic phases (predominantly Zr and steel). The code requires input that describes the containment geometry, melt “pour” conditions, and cavity atmospheric conditions (i.e., pressure, temperature, and cavity flooding information). For cases in which the cavity contains a preexisting water layer at the time of RPV failure, melt jet breakup and particle bed formation can be calculated mechanistically given the time-dependent melt pour conditions (input data) as well as the heatup and boiloff of water in the melt impingement zone (calculated). For core debris impacting either the containment floor or previously spread material, the code calculates the transient hydrodynamics and heat transfer which determine the spreading and freezing behavior of the melt. The code predicts conditions at the end of the spreading stage, including melt relocation distance, depth and material composition profiles, substrate ablation profile, and wall heatup. Code output can be used as input to other models such as CORQUENCH that evaluate long term core-concrete interaction behavior following the transient spreading stage. MELTSPREAD3 was originally developed to investigate BWR Mark I liner vulnerability, but has been substantially upgraded and applied to other reactor designs (e.g., the EPR), and more recently to the plant accidents at Fukushima Daiichi. The most recent round of

  8. Analysis of some antecipated transients without scram for PWR type reactors by coupling of the CORAN code to the ALMOD code system

    International Nuclear Information System (INIS)

    Carvalho, F. de A.T. de.

    1985-01-01

    This study investigates some antecipated transients without scram for a pressurized water cooled reactor, using coupling of the containment CORAN code to the ALMOD code system, under severe random conditions. This coupling has the objective of including containment model as part of an unified code system. These severe conditions include failure of reactor scram, following a station black-out and emergency power initiation for the burn-up status at the beginning and end of the cycle. Furthermore, for the burn-up status at the end of the cycle, a failure in the closure of the pressurizer relief valve was also investigated. (Author) [pt

  9. Physics options in the plasma code VOA

    International Nuclear Information System (INIS)

    Eltgroth, P.G.

    1976-06-01

    A two dimensional relativistic plasma physics code has been modified to accomodate general electromagnetic boundary conditions and various approximations of basic physics. The code can treat internal conductors and insulators, imposed electromagnetic fields, the effects of external circuitry and non-equilibrium starting conditions. Particle dynamics options include a full microscopic treatment, fully relaxed electrons, a low frequency electron approximation and a combination of approximations for specified zones. Electromagnetic options include the full wave treatment, an electrostatic approximation and two varieties of magnetohydrodynamic approximations in specified zones

  10. 7 CFR 46.44 - Good delivery.

    Science.gov (United States)

    2010-01-01

    ... Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE MARKETING OF PERISHABLE AGRICULTURAL COMMODITIES REGULATIONS (OTHER... conditions, will meet the following additional requirements on delivery at the contract destination: (a...

  11. Efficient Delivery of Scalable Video Using a Streaming Class Model

    Directory of Open Access Journals (Sweden)

    Jason J. Quinlan

    2018-03-01

    Full Text Available When we couple the rise in video streaming with the growing number of portable devices (smart phones, tablets, laptops, we see an ever-increasing demand for high-definition video online while on the move. Wireless networks are inherently characterised by restricted shared bandwidth and relatively high error loss rates, thus presenting a challenge for the efficient delivery of high quality video. Additionally, mobile devices can support/demand a range of video resolutions and qualities. This demand for mobile streaming highlights the need for adaptive video streaming schemes that can adjust to available bandwidth and heterogeneity, and can provide a graceful changes in video quality, all while respecting viewing satisfaction. In this context, the use of well-known scalable/layered media streaming techniques, commonly known as scalable video coding (SVC, is an attractive solution. SVC encodes a number of video quality levels within a single media stream. This has been shown to be an especially effective and efficient solution, but it fares badly in the presence of datagram losses. While multiple description coding (MDC can reduce the effects of packet loss on scalable video delivery, the increased delivery cost is counterproductive for constrained networks. This situation is accentuated in cases where only the lower quality level is required. In this paper, we assess these issues and propose a new approach called Streaming Classes (SC through which we can define a key set of quality levels, each of which can be delivered in a self-contained manner. This facilitates efficient delivery, yielding reduced transmission byte-cost for devices requiring lower quality, relative to MDC and Adaptive Layer Distribution (ALD (42% and 76% respective reduction for layer 2, while also maintaining high levels of consistent quality. We also illustrate how selective packetisation technique can further reduce the effects of packet loss on viewable quality by

  12. The Nordic Obstetric Surveillance Study: a study of complete uterine rupture, abnormally invasive placenta, peripartum hysterectomy, and severe blood loss at delivery.

    Science.gov (United States)

    Colmorn, Lotte B; Petersen, Kathrine B; Jakobsson, Maija; Lindqvist, Pelle G; Klungsoyr, Kari; Källen, Karin; Bjarnadottir, Ragnheidur I; Tapper, Anna-Maija; Børdahl, Per E; Gottvall, Karin; Thurn, Lars; Gissler, Mika; Krebs, Lone; Langhoff-Roos, Jens

    2015-07-01

    To assess the rates and characteristics of women with complete uterine rupture, abnormally invasive placenta, peripartum hysterectomy, and severe blood loss at delivery in the Nordic countries. Prospective, Nordic collaboration. The Nordic Obstetric Surveillance Study (NOSS) collected cases of severe obstetric complications in the Nordic countries from April 2009 to August 2012. Cases were reported by clinicians at the Nordic maternity units and retrieved from medical birth registers, hospital discharge registers, and transfusion databases by using International Classification of Diseases, 10th revision codes on diagnoses and the Nordic Medico-Statistical Committee Classification of Surgical Procedure codes. Rates of the studied complications and possible risk factors among parturients in the Nordic countries. The studied complications were reported in 1019 instances among 605 362 deliveries during the study period. The reported rate of severe blood loss at delivery was 11.6/10 000 deliveries, complete uterine rupture was 5.6/10 000 deliveries, abnormally invasive placenta was 4.6/10 000 deliveries, and peripartum hysterectomy was 3.5/10 000 deliveries. Of the women, 25% had two or more complications. Women with complications were more often >35 years old, overweight, with a higher parity, and a history of cesarean delivery compared with the total population. The studied obstetric complications are rare. Uniform definitions and valid reporting are essential for international comparisons. The main risk factors include previous cesarean section. The detailed information collected in the NOSS database provides a basis for epidemiologic studies, audits, and educational activities. © 2015 Nordic Federation of Societies of Obstetrics and Gynecology.

  13. Physical models and codes for prediction of activity release from defective fuel rods under operation conditions and in leakage tests during refuelling

    International Nuclear Information System (INIS)

    Likhanskii, V.; Evdokimov, I.; Khoruzhii, O.; Sorokin, A.; Novikov, V.

    2003-01-01

    It is appropriate to use the dependences, based on physical models, in the design-analytical codes for improving of reliability of defective fuel rod detection and for determination of defect characteristics by activity measuring in the primary coolant. In the paper the results on development of some physical models and integral mechanistic codes, assigned for prediction of defective fuel rod behaviour are presented. The analysis of mass transfer and mass exchange between fuel rod and coolant showed that the rates of these processes depends on many factors, such as coolant turbulent flow, pressure, effective hydraulic diameter of defect, fuel rod geometric parameters. The models, which describe these dependences, have been created. The models of thermomechanical fuel behaviour, stable gaseous FP release were modified and new computer code RTOP-CA was created thereupon for description of defective fuel rod behaviour and activity release into the primary coolant. The model of fuel oxidation in in-pile conditions, which includes radiolysis and RTOP-LT after validation of physical models are planned to be used for prediction of defective fuel rods behaviour

  14. Rural and Urban Differences in Vocational Rehabilitation Case Mix, Delivery Practices, and Employment Outcomes

    Science.gov (United States)

    Ipsen, Catherine; Swicegood, Grant

    2015-01-01

    Purpose: To examine rural and urban differences in Vocational Rehabilitation (VR) case mix, delivery practices, and employment outcomes. Methods: Rehabilitation Services Administration 911 (RSA-911) case data do not include location indicators that allow for rural analyses. We compiled RSA-911 data with county and ZIP code information from 47 VR…

  15. Manipulation of the Commodity Futures Market Delivery Process.

    OpenAIRE

    Pirrong, Stephen Craig

    1993-01-01

    An analysis of the futures market delivery 'end game' specifies necessary and sufficient conditions for long and short traders to manipulate futures prices at contract expiration. The empirical and welfare implications of manipulation are derived as well. Manipulation is most likely to occur in markets where economic frictions (such as transportation and transactions costs) make it inefficient to return excessive deliveries to their original owners. These consumption distortions induce price ...

  16. Assessing the INTERTRAN code for application in Asian environs

    International Nuclear Information System (INIS)

    Yoshimura, S.

    1986-10-01

    A Japanese study, which was carried out as part of the IAEA Coordinated Research Programme on Radiation Protection Implications of Transport Accidents Involving Radioactive Materials, provided evaluations of transport conditions of nuclear fuel in Japan. Nuclear fuel is transported in Japan in the form of UO 2 , UF 6 , fresh fuel assemblies and spent fuel. Based on these transport conditions calculations were made using the INTERTRAN code which was developed as part of the IAEA Coordinated Research Programme on Safe Transport of Radioactive Materials (1980-1985), for assessing doses to workers and to the public due to the transport of nuclear fuel. As a part of the study, a new code was developed for evaluating radiological impacts of the transport of radioactive materials. The code was also used for assessing doses from the transport of nuclear fuel in Japan. The results indicate that doses to workers and to the public due to the incident-free transport of nuclear fuel are low, i.e., of the order of 1-30 man mSv/100 km. The doses calculated by the Japanese code were in general slightly smaller than the doses calculated using the INTERTRAN code. The study concerned normal conditions of transport, i.e., no impact from incidents or accidents was evaluated. The study resulted, in addition, in some suggestions for further developing the INTERTRAN code

  17. Premature delivery

    Directory of Open Access Journals (Sweden)

    Bernardita Donoso Bernales

    2012-09-01

    Full Text Available Preterm delivery is the single most important cause of perinatal morbidity and mortality. In Chile, preterm births have increased in the past decade, although neonatal morbidity and mortality attributable to it shows a downward trend, thanks to improvements in neonatal care of premature babies, rather than the success of obstetric preventive and therapeutic strategies. This article describes clinical entities, disease processes and conditions that constitute predisposing factors of preterm birth, as well as an outline for the prevention and clinical management of women at risk of preterm birth.

  18. Selective encryption for H.264/AVC video coding

    Science.gov (United States)

    Shi, Tuo; King, Brian; Salama, Paul

    2006-02-01

    Due to the ease with which digital data can be manipulated and due to the ongoing advancements that have brought us closer to pervasive computing, the secure delivery of video and images has become a challenging problem. Despite the advantages and opportunities that digital video provide, illegal copying and distribution as well as plagiarism of digital audio, images, and video is still ongoing. In this paper we describe two techniques for securing H.264 coded video streams. The first technique, SEH264Algorithm1, groups the data into the following blocks of data: (1) a block that contains the sequence parameter set and the picture parameter set, (2) a block containing a compressed intra coded frame, (3) a block containing the slice header of a P slice, all the headers of the macroblock within the same P slice, and all the luma and chroma DC coefficients belonging to the all the macroblocks within the same slice, (4) a block containing all the ac coefficients, and (5) a block containing all the motion vectors. The first three are encrypted whereas the last two are not. The second method, SEH264Algorithm2, relies on the use of multiple slices per coded frame. The algorithm searches the compressed video sequence for start codes (0x000001) and then encrypts the next N bits of data.

  19. [Optimum approach to delivery for control of premature birth (author's transl)].

    Science.gov (United States)

    Nieder, J; Lattorff, E

    1980-01-01

    Foetal condition and neonatal mortality of 637 prematurely born children with birth weights below 2,501 g were analysed, depending on modes of delivery, such as spontaneous birth, speculum delivery, use of forceps, manual support, and caesarean section. The clinical condition of the newborn, assessed five minutes from parturition by Apgar score 1, was found to depend primarily on birth weight rather than on the mode of delivery. The average Apgar values were lower for less mature newborns. While Apgar scores were worst for newborns after caesarean section delivery, the differences between approaches to delivery could not be statistically secured. Neonatal mortality went up, according to expectation, along with dropping birth weight. The mortality rate of premature births below 1,501 g was not affected by delivery modes. Prophylactic use of Shute forceps and speculum delivery appeared to be superior to spontaneous birth in the medium weight class, between 1,501 g and 2,000 g. Yet, not even here were the differences between clear postnatal mortality rates statistically secured. -Lowest mortality figures were recorded from spontaneous birth in the weight class between 2,001 g and 2,500 g, but significant differences were established only to speculum delivery. Premature newborns after caesarean section had poorer prospects than all variants of vaginal birth, but among the latter premature births from breech presentation were more endangered than others. Decisions as to vaginal, abdominal, spontaneous proprophylactically surgical approaches to premature deliveries should be taken for every individual case and due consideration of many factors.

  20. Evaluation of the FRAPCON-3 Computer Code

    Energy Technology Data Exchange (ETDEWEB)

    Jernkvist, Lars Olof; Massih, Ali [Quantum Technologies AB, Uppsala (Sweden)

    2002-03-01

    The FRAPCON-3 computer code has been evaluated with respect to its applicability, modeling capability, user friendliness, source code structure and supporting experimental database. The code is intended for thermo-mechanical analyses of light water reactor nuclear fuel rods under steady-state operational conditions and moderate power excursions. It is applicable to both boiling- and pressurized water reactor fuel rods with UO{sub 2} fuel, ranging up to about 65 MWd/kg U in rod average burnup. The models and numerical methods in FRAPCON-3 are relatively simple, which makes the code transparent and also fairly easy to modify and extend for the user. The fundamental equations for heat transfer, structural analysis and fuel fission gas release are solved in one-dimensional (radial) and stationary (time-independent) form, and interaction between axial segments of the rod is confined to calculations of coolant axial flow and rod internal gas pressure. The code is fairly easy to use; fuel rod design data and time histories of fuel rod power and coolant inlet conditions are input via a single text file, and the corresponding calculated variation with time of important fuel rod parameters are printed to a single output file in textual form. The results can also be presented in graphical form through an interface to the general graphics program xmgr. FRAPCON-3 also provides the possibility to export calculated results to the transient fuel rod analysis code FRAPTRAN, where the data can be used as burnup-dependent initial conditions to a postulated transient. Most of the source code to FRAPCON-3 is written in Fortran-IV, which is an archaic, non-standard dialect of the Fortran programming language. Since Fortran-IV is not accepted by all compilers for the latest standard of the language, Fortran-95, there is a risk that the source code must be partly rewritten in the future. Documentation of the code comprises (i) a general code description, which briefly presents models

  1. Evaluation of the FRAPCON-3 Computer Code

    International Nuclear Information System (INIS)

    Jernkvist, Lars Olof; Massih, Ali

    2002-03-01

    The FRAPCON-3 computer code has been evaluated with respect to its applicability, modeling capability, user friendliness, source code structure and supporting experimental database. The code is intended for thermo-mechanical analyses of light water reactor nuclear fuel rods under steady-state operational conditions and moderate power excursions. It is applicable to both boiling- and pressurized water reactor fuel rods with UO 2 fuel, ranging up to about 65 MWd/kg U in rod average burnup. The models and numerical methods in FRAPCON-3 are relatively simple, which makes the code transparent and also fairly easy to modify and extend for the user. The fundamental equations for heat transfer, structural analysis and fuel fission gas release are solved in one-dimensional (radial) and stationary (time-independent) form, and interaction between axial segments of the rod is confined to calculations of coolant axial flow and rod internal gas pressure. The code is fairly easy to use; fuel rod design data and time histories of fuel rod power and coolant inlet conditions are input via a single text file, and the corresponding calculated variation with time of important fuel rod parameters are printed to a single output file in textual form. The results can also be presented in graphical form through an interface to the general graphics program xmgr. FRAPCON-3 also provides the possibility to export calculated results to the transient fuel rod analysis code FRAPTRAN, where the data can be used as burnup-dependent initial conditions to a postulated transient. Most of the source code to FRAPCON-3 is written in Fortran-IV, which is an archaic, non-standard dialect of the Fortran programming language. Since Fortran-IV is not accepted by all compilers for the latest standard of the language, Fortran-95, there is a risk that the source code must be partly rewritten in the future. Documentation of the code comprises (i) a general code description, which briefly presents models

  2. A wireless actuating drug delivery system

    International Nuclear Information System (INIS)

    Jo, Won-Jun; Baek, Seung-Ki; Park, Jung-Hwan

    2015-01-01

    A wireless actuating drug delivery system was devised. The system is based on induction heating for drug delivery. In this study, thermally generated nitrogen gas produced by induction heating of azobisisobutyronitrile (AIBN) was utilized for pressure-driven release of the drug. The delivery device consists of an actuator chamber, a drug reservoir, and a microchannel. A semicircular copper disc (5 and 6 mm in diameter and 100 µm thick), and thermal conductive tape were integrated as the heating element in the actuator chamber. The final device was 2.7 mm thick. 28 µl of drug solution were placed in the reservoir and the device released the drug quickly at the rate of 6 µl s −1 by induction heating at 160 µT of magnetic intensity. The entire drug solution was released and dispersed after subcutaneous implantation under identical experimental condition. This study demonstrates that the device was simply prepared and drug delivery could be achieved by wireless actuation of a thin, pressure-driven actuator. (paper)

  3. Data exchange between zero dimensional code and physics platform in the CFETR integrated system code

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Guoliang [School of Nuclear Science and Technology, University of Science and Technology of China, Hefei 230026 China (China); Shi, Nan [Institute of Plasma Physics, Chinese Academy of Sciences, No. 350 Shushanhu Road, Hefei (China); Zhou, Yifu; Mao, Shifeng [School of Nuclear Science and Technology, University of Science and Technology of China, Hefei 230026 China (China); Jian, Xiang [State Key Laboratory of Advanced Electromagnetic Engineering and Technology, School of Electrical and Electronics Engineering, Huazhong University of Science and Technology, Wuhan 430074 (China); Chen, Jiale [Institute of Plasma Physics, Chinese Academy of Sciences, No. 350 Shushanhu Road, Hefei (China); Liu, Li; Chan, Vincent [School of Nuclear Science and Technology, University of Science and Technology of China, Hefei 230026 China (China); Ye, Minyou, E-mail: yemy@ustc.edu.cn [School of Nuclear Science and Technology, University of Science and Technology of China, Hefei 230026 China (China)

    2016-11-01

    Highlights: • The workflow of the zero dimensional code and the multi-dimension physics platform of CFETR integrated system codeis introduced. • The iteration process among the codes in the physics platform. • The data transfer between the zero dimensionalcode and the physical platform, including data iteration and validation, and justification for performance parameters.. - Abstract: The China Fusion Engineering Test Reactor (CFETR) integrated system code contains three parts: a zero dimensional code, a physics platform and an engineering platform. We use the zero dimensional code to identify a set of preliminary physics and engineering parameters for CFETR, which is used as input to initiate multi-dimension studies using the physics and engineering platform for design, verification and validation. Effective data exchange between the zero dimensional code and the physical platform is critical for the optimization of CFETR design. For example, in evaluating the impact of impurity radiation on core performance, an open field line code is used to calculate the impurity transport from the first-wall boundary to the pedestal. The impurity particle in the pedestal are used as boundary conditions in a transport code for calculating impurity transport in the core plasma and the impact of core radiation on core performance. Comparison of the results from the multi-dimensional study to those from the zero dimensional code is used to further refine the controlled radiation model. The data transfer between the zero dimensional code and the physical platform, including data iteration and validation, and justification for performance parameters will be presented in this paper.

  4. METHOD OF CHOOSING THE TECHNOLOGY OF VEHICLE OPERATION ON DELIVERY ROUTES

    Directory of Open Access Journals (Sweden)

    Ye. Nagornyi

    2014-10-01

    Full Text Available A method for determining the technology of vehicles operation on delivery (team routes, which allows to determine the optimal sequence of cargo delivery to customers by vehicles of certain capacity in order to meet the requirements of cargo owners regarding the conditions of service is offered. Recommendations for creation of an automated system of forming the technology of vehicles operation on delivery routes are developed.

  5. Data Dissemination Based on Fuzzy Logic and Network Coding in Vehicular Networks

    Directory of Open Access Journals (Sweden)

    Xiaolan Tang

    2017-01-01

    Full Text Available Vehicular networks, as a significant technology in intelligent transportation systems, improve the convenience, efficiency, and safety of driving in smart cities. However, because of the high velocity, the frequent topology change, and the limited bandwidth, it is difficult to efficiently propagate data in vehicular networks. This paper proposes a data dissemination scheme based on fuzzy logic and network coding for vehicular networks, named SFN. It uses fuzzy logic to compute a transmission ability for each vehicle by comprehensively considering the effects of three factors: the velocity change rate, the velocity optimization degree, and the channel quality. Then, two nodes with high abilities are selected as primary backbone and slave backbone in every road segment, which propagate data to other vehicles in this segment and forward them to the backbones in the next segment. The backbone network helps to increase the delivery ratio and avoid invalid transmissions. Additionally, network coding is utilized to reduce transmission overhead and accelerate data retransmission in interbackbone forwarding and intrasegment broadcasting. Experiments show that, compared with existing schemes, SFN has a high delivery ratio and a short dissemination delay, while the backbone network keeps high reliability.

  6. OpenQ∗D simulation code for QCD+QED

    DEFF Research Database (Denmark)

    Campos, Isabel; Fritzsch, Patrick; Hansen, Martin

    2018-01-01

    The openQ∗D code for the simulation of QCD+QED with C∗ boundary conditions is presented. This code is based on openQCD-1.6, from which it inherits the core features that ensure its efficiency: the locally-deflated SAP-preconditioned GCR solver, the twisted-mass frequency splitting of the fermion....... An alpha version of this code is publicly available and can be downloaded from http://rcstar.web.cern.ch/....

  7. An implicit Smooth Particle Hydrodynamic code

    Energy Technology Data Exchange (ETDEWEB)

    Knapp, Charles E. [Univ. of New Mexico, Albuquerque, NM (United States)

    2000-05-01

    An implicit version of the Smooth Particle Hydrodynamic (SPH) code SPHINX has been written and is working. In conjunction with the SPHINX code the new implicit code models fluids and solids under a wide range of conditions. SPH codes are Lagrangian, meshless and use particles to model the fluids and solids. The implicit code makes use of the Krylov iterative techniques for solving large linear-systems and a Newton-Raphson method for non-linear corrections. It uses numerical derivatives to construct the Jacobian matrix. It uses sparse techniques to save on memory storage and to reduce the amount of computation. It is believed that this is the first implicit SPH code to use Newton-Krylov techniques, and is also the first implicit SPH code to model solids. A description of SPH and the techniques used in the implicit code are presented. Then, the results of a number of tests cases are discussed, which include a shock tube problem, a Rayleigh-Taylor problem, a breaking dam problem, and a single jet of gas problem. The results are shown to be in very good agreement with analytic solutions, experimental results, and the explicit SPHINX code. In the case of the single jet of gas case it has been demonstrated that the implicit code can do a problem in much shorter time than the explicit code. The problem was, however, very unphysical, but it does demonstrate the potential of the implicit code. It is a first step toward a useful implicit SPH code.

  8. Debarring from succession – Comparing the regulations of the former civil code and the New Civil Code from 2009

    Directory of Open Access Journals (Sweden)

    Ioana NICOLAE

    2012-01-01

    Full Text Available This paper presents the changes in the legal framework regarding succession issue. These changes have been examined in light of three hypotheses arising from the former Civil Code. The distinction between judiciary debarring and lawful debarring introduced by the New Civil Code from 2009 is also presented. The conditions for cancelling the effects of debarring from succession stipulated by the New Civil Code are explained. Finally, several legal circumstances for declaring a person unworthy of succession are comparatively presented.

  9. From concatenated codes to graph codes

    DEFF Research Database (Denmark)

    Justesen, Jørn; Høholdt, Tom

    2004-01-01

    We consider codes based on simple bipartite expander graphs. These codes may be seen as the first step leading from product type concatenated codes to more complex graph codes. We emphasize constructions of specific codes of realistic lengths, and study the details of decoding by message passing...

  10. Analysis of Market Opportunities for Chinese Private Express Delivery Industry

    Science.gov (United States)

    Jiang, Changbing; Bai, Lijun; Tong, Xiaoqing

    China's express delivery market has become the arena in which each express enterprise struggles to chase due to the huge potential demand and high profitable prospects. So certain qualitative and quantitative forecast for the future changes of China's express delivery market will help enterprises understand various types of market conditions and social changes in demand and adjust business activities to enhance their competitiveness timely. The development of China's express delivery industry is first introduced in this chapter. Then the theoretical basis of the regression model is overviewed. We also predict the demand trends of China's express delivery market by using Pearson correlation analysis and regression analysis from qualitative and quantitative aspects, respectively. Finally, we draw some conclusions and recommendations for China's express delivery industry.

  11. Recent developments in the CONTAIN-LMR code

    International Nuclear Information System (INIS)

    Murata, K.K.

    1990-01-01

    Through an international collaborative effort, a special version of the CONTAIN code is being developed for integrated mechanistic analysis of the conditions in liquid metal reactor (LMR) containments during severe accidents. The capabilities of the most recent code version, CONTAIN LMR/1B-Mod.1, are discussed. These include new models for the treatment of two condensables, sodium condensation on aerosols, chemical reactions, hygroscopic aerosols, and concrete outgassing. This code version also incorporates all of the previously released LMR model enhancements. The results of an integral demonstration calculation of a sever core-melt accident scenario are given to illustrate the features of this code version. 11 refs., 7 figs., 1 tab

  12. OM Code Requirements For MOVs -- OMN-1 and Appendix III

    Energy Technology Data Exchange (ETDEWEB)

    Kevin G. DeWall

    2011-08-01

    The purpose or scope of the ASME OM Code is to establish the requirements for pre-service and in-service testing of nuclear power plant components to assess their operational readiness. For MOVs this includes those that perform a specific function in shutting down a reactor to the safe shutdown condition, maintaining the safe shutdown condition, and mitigating the consequences of an accident. This paper will present a brief history of industry and regulatory activities related to MOVs and the development of Code requirements to address weaknesses in earlier versions of the OM Code. The paper will discuss the MOV requirements contained in the 2009 version of ASME OM Code, specifically Mandatory Appendix III and OMN-1, Revision 1.

  13. OM Code Requirements For MOVs -- OMN-1 and Appendix III

    International Nuclear Information System (INIS)

    DeWall, Kevin G.

    2011-01-01

    The purpose or scope of the ASME OM Code is to establish the requirements for pre-service and in-service testing of nuclear power plant components to assess their operational readiness. For MOVs this includes those that perform a specific function in shutting down a reactor to the safe shutdown condition, maintaining the safe shutdown condition, and mitigating the consequences of an accident. This paper will present a brief history of industry and regulatory activities related to MOVs and the development of Code requirements to address weaknesses in earlier versions of the OM Code. The paper will discuss the MOV requirements contained in the 2009 version of ASME OM Code, specifically Mandatory Appendix III and OMN-1, Revision 1.

  14. GFP expression by intracellular gene delivery of GFP-coding fragments using nanocrystal quantum dots

    International Nuclear Information System (INIS)

    Hoshino, Akiyoshi; Manabe, Noriyoshi; Fujioka, Kouki; Hanada, Sanshiro; Yamamoto, Kenji; Yasuhara, Masato; Kondo, Akihiko

    2008-01-01

    Gene therapy is an attractive approach to supplement a deficient gene function. Although there has been some success with specific gene delivery using various methods including viral vectors and liposomes, most of these methods have a limited efficiency or also carry a risk for oncogenesis. We herein report that quantum dots (QDs) conjugated with nuclear localizing signal peptides (NLSP) successfully introduced gene-fragments with promoter elements, which promoted the expression of the enhanced green fluorescent protein (eGFP) gene in mammalian cells. The expression of eGFP protein was observed when the QD/gene-construct was added to the culture media. The gene-expression efficiency varied depending on multiple factors around QDs, such as (1) the reading direction of the gene-fragments, (2) the quantity of gene-fragments attached on the surface of the QD-constructs, (3) the surface electronic charges varied according to the structure of the QD/gene-constructs, and (4) the particle size of QD/gene complex varied according to the structure and amounts of gene-fragments. Using this QD/gene-construct system, eGFP protein could be detected 28 days after the gene-introduction whereas the fluorescence of QDs had disappeared. This system therefore provides another method for the intracellular delivery of gene-fragments without using either viral vectors or specific liposomes.

  15. Building climate change into infrastructure codes and standards

    International Nuclear Information System (INIS)

    Auld, H.; Klaasen, J.; Morris, R.; Fernandez, S.; MacIver, D.; Bernstein, D.

    2009-01-01

    'Full text:' Building codes and standards and the climatic design values embedded within these legal to semi-legal documents have profound safety, health and economic implications for Canada's infrastructure systems. The climatic design values that have been used for the design of almost all of today's more than $5.5 Trillion in infrastructure are based on historical climate data and assume that the extremes of the past will represent future conditions. Since new infrastructure based on codes and standards will be built to survive for decades to come, it is critically important that existing climatic design information be as accurate and up-to-date as possible, that the changing climate be monitored to detect and highlight vulnerabilities of existing infrastructure, that forensic studies of climate-related failures be undertaken and that codes and standards processes incorporate future climates and extremes as much as possible. Uncertainties in the current climate change models and their scenarios currently challenge our ability to project future extremes regionally and locally. Improvements to the spatial and temporal resolution of these climate change scenarios, along with improved methodologies to treat model biases and localize results, will allow future codes and standards to better reflect the extremes and weathering conditions expected over the lifespan of structures. In the meantime, other information and code processes can be used to incorporate changing climate conditions into upcoming infrastructure codes and standards, to “bridge” the model uncertainty gap and to complement the state of existing projections. This presentation will outline some of the varied information and processes that will be used to incorporate climate change adaptation into the next development cycle of the National Building Code of Canada and numerous other national CSA infrastructure standards. (author)

  16. Development of chemical equilibrium analysis code 'CHEEQ'

    International Nuclear Information System (INIS)

    Nagai, Shuichiro

    2006-08-01

    'CHEEQ' code which calculates the partial pressure and the mass of the system consisting of ideal gas and pure condensed phase compounds, was developed. Characteristics of 'CHEEQ' code are as follows. All the chemical equilibrium equations were described by the formation reactions from the mono-atomic gases in order to simplify the code structure and input preparation. Chemical equilibrium conditions, Σν i μ i =0 for the gaseous compounds and precipitated condensed phase compounds and Σν i μ i > 0 for the non-precipitated condensed phase compounds, were applied. Where, ν i and μ i are stoichiometric coefficient and chemical potential of component i. Virtual solid model was introduced to perform the calculation of constant partial pressure condition. 'CHEEQ' was consisted of following 3 parts, (1) analysis code, zc132. f. (2) thermodynamic data base, zmdb01 and (3) input data file, zindb. 'CHEEQ' code can calculate the system which consisted of elements (max.20), condensed phase compounds (max.100) and gaseous compounds. (max.200). Thermodynamic data base, zmdb01 contains about 1000 elements and compounds, and 200 of them were Actinide elements and their compounds. This report describes the basic equations, the outline of the solution procedure and instructions to prepare the input data and to evaluate the calculation results. (author)

  17. A global health delivery framework approach to epilepsy care in resource-limited settings.

    Science.gov (United States)

    Cochran, Maggie F; Berkowitz, Aaron L

    2015-11-15

    The Global Health Delivery (GHD) framework (Farmer, Kim, and Porter, Lancet 2013;382:1060-69) allows for the analysis of health care delivery systems along four axes: a care delivery value chain that incorporates prevention, diagnosis, and treatment of a medical condition; shared delivery infrastructure that integrates care within existing healthcare delivery systems; alignment of care delivery with local context; and generation of economic growth and social development through the health care delivery system. Here, we apply the GHD framework to epilepsy care in rural regions of low- and middle-income countries (LMIC) where there are few or no neurologists. Copyright © 2015 Elsevier B.V. All rights reserved.

  18. Immunization delivery in British Columbia

    Science.gov (United States)

    Omura, John; Buxton, Jane; Kaczorowski, Janusz; Catterson, Jason; Li, Jane; Derban, Andrea; Hasselback, Paul; Machin, Shelagh; Linekin, Michelle; Morgana, Tamsin; O’Briain, Barra; Scheifele, David; Dawar, Meena

    2014-01-01

    Abstract Objective To explore the experiences of family physicians and pediatricians delivering immunizations, including perceived barriers and supports. Design Qualitative study using focus groups. Setting Ten cities throughout British Columbia. Participants A total of 46 family physicians or general practitioners, 10 pediatricians, and 2 residents. Methods A semistructured dialogue guide was used by a trained facilitator to explore participants’ experiences and views related to immunization delivery in British Columbia. Verbatim transcriptions were independently coded by 2 researchers. Key themes were analyzed and identified in an iterative manner using interpretive description. Main findings Physicians highly valued vaccine delivery. Factors facilitating physician-delivered immunizations included strong beliefs in the value of vaccines and having adequate information. Identified barriers included the large time commitment and insufficient communication about program changes, new vaccines, and the adult immunization program in general. Some physicians reported good relationships with local public health, while others reported the opposite experience, and this varied by geographic location. Conclusion These findings suggest that physicians are supportive of delivering vaccines. However, there are opportunities to improve the sustainability of physician-delivered immunizations. While compensation schemes remain under the purview of the provincial governments, local public health authorities can address the information needs of physicians. PMID:24627403

  19. Validation uncertainty of MATRA code for subchannel void distributions

    Energy Technology Data Exchange (ETDEWEB)

    Hwang, Dae-Hyun; Kim, S. J.; Kwon, H.; Seo, K. W. [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2014-10-15

    To extend code capability to the whole core subchannel analysis, pre-conditioned Krylov matrix solvers such as BiCGSTAB and GMRES are implemented in MATRA code as well as parallel computing algorithms using MPI and OPENMP. It is coded by fortran 90, and has some user friendly features such as graphic user interface. MATRA code was approved by Korean regulation body for design calculation of integral-type PWR named SMART. The major role subchannel code is to evaluate core thermal margin through the hot channel analysis and uncertainty evaluation for CHF predictions. In addition, it is potentially used for the best estimation of core thermal hydraulic field by incorporating into multiphysics and/or multi-scale code systems. In this study we examined a validation process for the subchannel code MATRA specifically in the prediction of subchannel void distributions. The primary objective of validation is to estimate a range within which the simulation modeling error lies. The experimental data for subchannel void distributions at steady state and transient conditions was provided on the framework of OECD/NEA UAM benchmark program. The validation uncertainty of MATRA code was evaluated for a specific experimental condition by comparing the simulation result and experimental data. A validation process should be preceded by code and solution verification. However, quantification of verification uncertainty was not addressed in this study. The validation uncertainty of the MATRA code for predicting subchannel void distribution was evaluated for a single data point of void fraction measurement at a 5x5 PWR test bundle on the framework of OECD UAM benchmark program. The validation standard uncertainties were evaluated as 4.2%, 3.9%, and 2.8% with the Monte-Carlo approach at the axial levels of 2216 mm, 2669 mm, and 3177 mm, respectively. The sensitivity coefficient approach revealed similar results of uncertainties but did not account for the nonlinear effects on the

  20. Nanocarriers in ocular drug delivery: an update review.

    Science.gov (United States)

    Wadhwa, Sheetu; Paliwal, Rishi; Paliwal, Shivani Rai; Vyas, S P

    2009-01-01

    Controlled drug delivery to eye is one of the most challenging fields of pharmaceutical research. Low drug-contact time and poor ocular bioavailability due to drainage of solution, tear turnover and its dilution or lacrimation are the problems associated with conventional systems. In addition, anatomical barriers and physiological conditions of eye are also important parameters which control designing of drug delivery systems. Nanosized carriers like micro/nano-suspensions, liposome, niosome, dendrimer, nanoparticles, ocular inserts, implants, hydrogels and prodrug approaches have been developed for this purpose. These novel systems offer manifold advantages over conventional systems as they increase the efficiency of drug delivery by improving the release profile and also reduce drug toxicity. Conventional delivery systems get diluted with tear, washed away through the lacrimal gland and usually require administering at regular time intervals whereas nanocarriers release drug at constant rate for a prolonged period of time and thus enhance its absorption and site specific delivery. This review presents an overview of the various aspects of the ocular drug delivery, with special emphasis on nanocarrier based strategies, including structure of eye, its barriers, delivery routes and the challenges/limitations associated with development of novel nanocarriers. The recent progresses in therapy of ocular disease like gene therapy have also been included so that future options should also be considered from the delivery point of view. Recent progress in the delivery of proteins and peptides via ocular route has also been incorporated for reader benefit.

  1. Peptide and protein delivery using new drug delivery systems.

    Science.gov (United States)

    Jain, Ashish; Jain, Aviral; Gulbake, Arvind; Shilpi, Satish; Hurkat, Pooja; Jain, Sanjay K

    2013-01-01

    Pharmaceutical and biotechnological research sorts protein drug delivery systems by importance based on their various therapeutic applications. The effective and potent action of the proteins/peptides makes them the drugs of choice for the treatment of numerous diseases. Major research issues in protein delivery include the stabilization of proteins in delivery devices and the design of appropriate target-specific protein carriers. Many efforts have been made for effective delivery of proteins/peptidal drugs through various routes of administrations for successful therapeutic effects. Nanoparticles made of biodegradable polymers such as poly lactic acid, polycaprolactone, poly(lactic-co-glycolic acid), the poly(fumaric-co-sebacic) anhydride chitosan, and modified chitosan, as well as solid lipids, have shown great potential in the delivery of proteins/peptidal drugs. Moreover, scientists also have used liposomes, PEGylated liposomes, niosomes, and aquasomes, among others, for peptidal drug delivery. They also have developed hydrogels and transdermal drug delivery systems for peptidal drug delivery. A receptor-mediated delivery system is another attractive strategy to overcome the limitation in drug absorption that enables the transcytosis of the protein across the epithelial barrier. Modification such as PEGnology is applied to various proteins and peptides of the desired protein and peptides also increases the circulating life, solubility and stability, pharmacokinetic properties, and antigenicity of protein. This review focuses on various approaches for effective protein/peptidal drug delivery, with special emphasis on insulin delivery.

  2. openQ*D simulation code for QCD+QED

    Science.gov (United States)

    Campos, Isabel; Fritzsch, Patrick; Hansen, Martin; Krstić Marinković, Marina; Patella, Agostino; Ramos, Alberto; Tantalo, Nazario

    2018-03-01

    The openQ*D code for the simulation of QCD+QED with C* boundary conditions is presented. This code is based on openQCD-1.6, from which it inherits the core features that ensure its efficiency: the locally-deflated SAP-preconditioned GCR solver, the twisted-mass frequency splitting of the fermion action, the multilevel integrator, the 4th order OMF integrator, the SSE/AVX intrinsics, etc. The photon field is treated as fully dynamical and C* boundary conditions can be chosen in the spatial directions. We discuss the main features of openQ*D, and we show basic test results and performance analysis. An alpha version of this code is publicly available and can be downloaded from http://rcstar.web.cern.ch/.

  3. COOLII code conversion from Cyber to HP

    International Nuclear Information System (INIS)

    Lee, Hae Cho; Kim, Hee Kyung

    1996-06-01

    COOLII computer code determines the time required to cooldown the plant from shutdown cooling system initiation condition to cold shutdown or refueling condition. Required time for cooldown is calculated under the various assumption on shutdown cooling heat exchanger(SDCHX) availability, reactor coolant system (RCS) low pressure safety injection(LPSI) flowrate. RCS cooldown rates and component cooling system flow rates. This report firstly describes detailed work carried out for installation of COOLII on HP 9000/700 series as well as relevant code validation results. Attached is a report on software verification and validation results. 7 refs. (Author) .new

  4. NASA Lewis Steady-State Heat Pipe Code Architecture

    Science.gov (United States)

    Mi, Ye; Tower, Leonard K.

    2013-01-01

    NASA Glenn Research Center (GRC) has developed the LERCHP code. The PC-based LERCHP code can be used to predict the steady-state performance of heat pipes, including the determination of operating temperature and operating limits which might be encountered under specified conditions. The code contains a vapor flow algorithm which incorporates vapor compressibility and axially varying heat input. For the liquid flow in the wick, Darcy s formula is employed. Thermal boundary conditions and geometric structures can be defined through an interactive input interface. A variety of fluid and material options as well as user defined options can be chosen for the working fluid, wick, and pipe materials. This report documents the current effort at GRC to update the LERCHP code for operating in a Microsoft Windows (Microsoft Corporation) environment. A detailed analysis of the model is presented. The programming architecture for the numerical calculations is explained and flowcharts of the key subroutines are given

  5. Benchmarking of codes for electron cyclotron heating and electron cyclotron current drive under ITER conditions

    NARCIS (Netherlands)

    Prater, R.; Farina, D.; Gribov, Y.; Harvey, R. W.; Ram, A. K.; Lin-Liu, Y. R.; Poli, E.; Smirnov, A. P.; Volpe, F.; Westerhof, E.; Zvonkovo, A.

    2008-01-01

    Optimal design and use of electron cyclotron heating requires that accurate and relatively quick computer codes be available for prediction of wave coupling, propagation, damping and current drive at realistic levels of EC power. To this end, a number of codes have been developed in laboratories

  6. Ultrasound strain imaging using Barker code

    Science.gov (United States)

    Peng, Hui; Tie, Juhong; Guo, Dequan

    2017-01-01

    Ultrasound strain imaging is showing promise as a new way of imaging soft tissue elasticity in order to help clinicians detect lesions or cancers in tissues. In this paper, Barker code is applied to strain imaging to improve its quality. Barker code as a coded excitation signal can be used to improve the echo signal-to-noise ratio (eSNR) in ultrasound imaging system. For the Baker code of length 13, the sidelobe level of the matched filter output is -22dB, which is unacceptable for ultrasound strain imaging, because high sidelobe level will cause high decorrelation noise. Instead of using the conventional matched filter, we use the Wiener filter to decode the Barker-coded echo signal to suppress the range sidelobes. We also compare the performance of Barker code and the conventional short pulse in simulation method. The simulation results demonstrate that the performance of the Wiener filter is much better than the matched filter, and Baker code achieves higher elastographic signal-to-noise ratio (SNRe) than the short pulse in low eSNR or great depth conditions due to the increased eSNR with it.

  7. MINI-SLAR delivery system

    International Nuclear Information System (INIS)

    Alstein, D.

    1996-01-01

    In the Spring of 1993, a need to complete Spacer Location and Repositioning (SLAR) on the Bruce 'A', Unit 1 Reactor was identified. An alternate SLAR delivery system was required due to conversion constraints that prevented the existing Bruce SLAR System from being used in Unit 1. A Portable SLAR Delivery System called MINI-SLAR Delivery System was developed, designed and fabricated in a 14 month period, then used to successfully SLAR 109 channels. The system is a portable remotely operated Nuclear Class 1 registered fitting that is independent of the Fuelling Machine, allowing the station to continue normal Fuelling and Maintenance activities. It is designed to a Level 'D' faulted condition of HPECI Pressure thus minimizing PHT Heat Sink configuration requirements and minimizing outage set-up times. The system is based on a modular design allowing for easy fabrication, assembly and repair. It consists of a Snout Assembly, a Closure Plug Assembly, Shield Plug Assembly, SLAR Ram assembly, Work Table Assembly and Control Panel. Controls are through a Programmable Logic Controller with software tested and certified to a Software Quality Assurance of Level Ill. (author). 2 refs., 2 figs

  8. MINI-SLAR delivery system

    Energy Technology Data Exchange (ETDEWEB)

    Alstein, D [Ontario Hydro, Tiverton, ON (Canada). Bruce Nuclear Generating Station-A; Dalton, K [Spectrum Engineering, Peterborough, ON (Canada)

    1997-12-31

    In the Spring of 1993, a need to complete Spacer Location and Repositioning (SLAR) on the Bruce `A`, Unit 1 Reactor was identified. An alternate SLAR delivery system was required due to conversion constraints that prevented the existing Bruce SLAR System from being used in Unit 1. A Portable SLAR Delivery System called MINI-SLAR Delivery System was developed, designed and fabricated in a 14 month period, then used to successfully SLAR 109 channels. The system is a portable remotely operated Nuclear Class 1 registered fitting that is independent of the Fuelling Machine, allowing the station to continue normal Fuelling and Maintenance activities. It is designed to a Level `D` faulted condition of HPECI Pressure thus minimizing PHT Heat Sink configuration requirements and minimizing outage set-up times. The system is based on a modular design allowing for easy fabrication, assembly and repair. It consists of a Snout Assembly, a Closure Plug Assembly, Shield Plug Assembly, SLAR Ram assembly, Work Table Assembly and Control Panel. Controls are through a Programmable Logic Controller with software tested and certified to a Software Quality Assurance of Level Ill. (author). 2 refs., 2 figs.

  9. Drug delivery from the oral cavity: a focus on mucoadhesive buccal drug delivery systems.

    Science.gov (United States)

    Shinkar, Dattatraya Manohar; Dhake, Avinash Sridhar; Setty, Chitral Mallikarjuna

    2012-01-01

    Since the early 1980s the concept of mucoadhesion has gained considerable interest in pharmaceutical technology. The various advantages associated with these systems made buccal drug delivery as a novel route of drug administration. It prolongs the residence time of the dosage form at the site of application. These systems remain in close contact with the absorption tissue, the mucous membrane, and thus contribute to improved and/or better therapeutic performance of the drug and of both local and systemic effects. This review highlights the anatomy and structure of oral mucosa, mechanism and theories of mucoadhesion, factors affecting mucoadhesion, characteristics and properties of desired mucoadhesive polymers, various types of dosage forms, and general considerations in design of mucoadhesive buccal dosage forms, permeation enhancers, and evaluation methods. Over the past few decades the mucoadhesive buccal drug delivery system has received a great deal of attention to develop mucoadhesive dosage forms to enable the prolonged retention at the site of action, providing a controlled release of drug for improved therapeutic outcome. Mucoadhesive drug delivery gives facility to include a permeation enhancer/enzyme inhibitor or pHmodifier in the formulation and versatility in designing as multidirectional or unidirectional release systems for local and systemic action. Local delivery to tissues of the oral cavity has a number of applications, including treatment of local conditions such as periodontal disease, bacterial and fungal infections, and aphthous stomatitis and vesiculo bullous diseases. For the treatment of chronic diseases, the mucoadhesive buccal drug delivery system allows easily accessibility and is generally well-accepted for administeringdrugs by systemic action.

  10. SIMULATE-3 K coupled code applications

    Energy Technology Data Exchange (ETDEWEB)

    Joensson, Christian [Studsvik Scandpower AB, Vaesteraas (Sweden); Grandi, Gerardo; Judd, Jerry [Studsvik Scandpower Inc., Idaho Falls, ID (United States)

    2017-07-15

    This paper describes the coupled code system TRACE/SIMULATE-3 K/VIPRE and the application of this code system to the OECD PWR Main Steam Line Break. A short description is given for the application of the coupled system to analyze DNBR and the flexibility the system creates for the user. This includes the possibility to compare and evaluate the result with the TRACE/SIMULATE-3K (S3K) coupled code, the S3K standalone code (core calculation) as well as performing single-channel calculations with S3K and VIPRE. This is the typical separate-effect-analyses required for advanced calculations in order to develop methodologies to be used for safety analyses in general. The models and methods of the code systems are presented. The outline represents the analysis approach starting with the coupled code system, reactor and core model calculation (TRACE/S3K). This is followed by a more detailed core evaluation (S3K standalone) and finally a very detailed thermal-hydraulic investigation of the hot pin condition (VIPRE).

  11. ''Iodine delivery rate'' with catheterangiography under pressure conditions of hand injection

    International Nuclear Information System (INIS)

    Busch, H.P.; Stocker, K.P.

    1998-01-01

    Purpose: The aim of this study was to record the flow-rate and to calculate the 'iodine delivery rate' (IDR) of contrast media of various viscosities when the contrast media are injected by hand. Methods: Five different catheters for coronary angiography were tested with the injection system Medral Mark V Plus. Injections were performed with pressures of 100, 200 and 400 PSI. The contrast media examined were Imeron 350, Imeron 400, Omnipaque 350 and Ultravist 370. The IDR was calculated on the basis of the measured flow rate and the Iodine content of the contrast medium. Results: As was expected, the IDR was higher as the pressure increased. In addition to the iodine content the viscosity of the contrast medium is a very important factor for the IDR. At both 100 PSI and 200 PSI the increase of the IDR was higher with Imeron 350 than with Imeron 400. The comparison of contrast media with identical iodine contents but differing viscosities (Imeron 350, Omnipaque 350) clearly showed that the IDR depended on viscosity. Conclusion: The 'iodine delivery rate' is a decisive factor in the opacification of arterial vessels. Both iodine content and viscosity of a contrast medium are important for the IDR. Because of the low pressure at manual injection, contrast media with low viscosities should be used. A further possibility to increase the IDR is warming-up the contrast medium to body temperature. (orig.) [de

  12. Development and application of the BOA code in Spain

    International Nuclear Information System (INIS)

    Tortuero Lopez, C.; Doncel Gutierrez, N.; Culebras, F.

    2012-01-01

    The BOA code allows to quantitatively establish the level of risk of Axial Offset Anomaly and increased deposition of crud on the basis of specific conditions in each case. For this reason, the code is parameterized according to the individual characteristics of each plant. This paper summarizes the results obtained in the implementation of the code, as well as its future perspective.

  13. 50 CFR Table 1a to Part 679 - Delivery Condition and Product Codes

    Science.gov (United States)

    2010-10-01

    .... Includes all internal organs (ancillary only). 35 Surimi. Paste from fish flesh and additives. 30 Whole fish or shellfish/food fish. 01 Wings. On skates, side fins are cut off next to body. 13 SHELLFISH ONLY... Bled only. Throat or isthmus slit to allow blood to drain. 03 Bled fish destined for fish meal...

  14. Toric Varieties and Codes, Error-correcting Codes, Quantum Codes, Secret Sharing and Decoding

    DEFF Research Database (Denmark)

    Hansen, Johan Peder

    We present toric varieties and associated toric codes and their decoding. Toric codes are applied to construct Linear Secret Sharing Schemes (LSSS) with strong multiplication by the Massey construction. Asymmetric Quantum Codes are obtained from toric codes by the A.R. Calderbank P.W. Shor and A.......M. Steane construction of stabilizer codes (CSS) from linear codes containing their dual codes....

  15. A computer code to design liquid containers for vehicles

    International Nuclear Information System (INIS)

    Parizi, H.B.; Fard, M.P.; Dolatabadi, A.

    2003-01-01

    We are presenting the development of a modular code for the simulation of the fluid sloshing that occurs in the liquid containers in vehicles. Sloshing occurs when a partially filled container of liquid goes through transient or steady external forces. Under such conditions, the free surface of the liquid may move and the liquid may impact on the walls of the container, exchanging forces. These forces may cause numerous harmful and undesirable consequences in the operation of the vehicle, such as vehicle turn over. The fluid mechanic equations that describe the fluid sloshing in the container and the dynamic equations that describe the movement of the container are solved separately in two different codes. The codes are coupled weekly, such that the output of one code will be used as the input to the other code in the same time step. The outputs of the fluid code are the forces and torques that are applied to the body of the container due to sloshing, whereas the output of the dynamic code are the translational and rotational velocities and accelerations of the container. The proposed software can be used to test the performance of the designed container under various operating condition and allow effective improvements to the container design. The proposed code is different than the presently available codes, in that it will provide a true simulation of the coupled fluid and structure interaction. (author)

  16. High efficiency video coding (HEVC) algorithms and architectures

    CERN Document Server

    Budagavi, Madhukar; Sullivan, Gary

    2014-01-01

    This book provides developers, engineers, researchers and students with detailed knowledge about the High Efficiency Video Coding (HEVC) standard. HEVC is the successor to the widely successful H.264/AVC video compression standard, and it provides around twice as much compression as H.264/AVC for the same level of quality. The applications for HEVC will not only cover the space of the well-known current uses and capabilities of digital video – they will also include the deployment of new services and the delivery of enhanced video quality, such as ultra-high-definition television (UHDTV) and video with higher dynamic range, wider range of representable color, and greater representation precision than what is typically found today. HEVC is the next major generation of video coding design – a flexible, reliable and robust solution that will support the next decade of video applications and ease the burden of video on world-wide network traffic. This book provides a detailed explanation of the various parts ...

  17. Development of HTGR plant dynamics simulation code

    International Nuclear Information System (INIS)

    Ohashi, Kazutaka; Tazawa, Yujiro; Mitake, Susumu; Suzuki, Katsuo.

    1987-01-01

    Plant dynamics simulation analysis plays an important role in the design work of nuclear power plant especially in the plant safety analysis, control system analysis, and transient condition analysis. The authors have developed the plant dynamics simulation code named VESPER, which is applicable to the design work of High Temperature Engineering Test Reactor, and have been improving the code corresponding to the design changes made in the subsequent design works. This paper describes the outline of VESPER code and shows its sample calculation results selected from the recent design work. (author)

  18. SU-E-T-403: Evaluation of the Beam Performance of a Varian TrueBeam Linear Accelerator Under External Device-Based Gated Delivery Conditions

    International Nuclear Information System (INIS)

    Kobulnicky, K; Pawlak, D; Purwar, A

    2015-01-01

    Purpose: To examine the beam performance of a Varian TrueBeam linear accelerator under external device-based gated delivery conditions. Methods: Six gating cycles were used to evaluate the gating performance of a standard production TrueBeam system that was not specially tuned in any way. The system was equipped with a factory installed external gating interface (EXGI). An in-house EXGI tester box was used to simulate the input gating signals. The gating cycles were selected based on long beam-on and short beam-off times, short beam-on and long beam-off times, or equal beam on and off times to check linac performance. The beam latencies were measured as the time difference between the logic high gating signal and the first or last target pulses with an oscilloscope. Tissue-Phantom Ratio, beam flatness, and dose distributions from 5 different plans were measured using the 6 different gating durations and the un-gated irradiation. A PTW 729 2-D array was used to compare 5 plans versus the un-gated delivery with a 1%/1mm gamma index passing criteria. Results: The beam latencies of the linac were based off of 20 samples for beam-on and beam-off, for each gating cycle. The average beam-on delays were measured to be between 57 and 66msec, with a maximum of 88 msec. The beam off latencies averaged between 19 and 26msec, with a maximum of 48 msec. TPR20,10 measurements showed beam energy stability within 0.5% of the un-gated delivery. Beam flatness was better than 2.5% for all gated cycles. All but two deliveries, the open field with 4 seconds on, 1 second off, and a five field IMRT plan with 0.5 seconds on, 2.5 seconds off, had >90% passing rate. Conclusion: TrueBeam demonstrates excellent beam stability with minimal beam latencies under external device-based gated operations. Dosimetric measurements show minimal variation in beam energy, flatness, and plan delivery. Authors are employees of Varian Medical Systems, Inc

  19. SU-E-T-403: Evaluation of the Beam Performance of a Varian TrueBeam Linear Accelerator Under External Device-Based Gated Delivery Conditions

    Energy Technology Data Exchange (ETDEWEB)

    Kobulnicky, K; Pawlak, D; Purwar, A [Varian Medical Systems, Inc., Palo Alto, CA (United States)

    2015-06-15

    Purpose: To examine the beam performance of a Varian TrueBeam linear accelerator under external device-based gated delivery conditions. Methods: Six gating cycles were used to evaluate the gating performance of a standard production TrueBeam system that was not specially tuned in any way. The system was equipped with a factory installed external gating interface (EXGI). An in-house EXGI tester box was used to simulate the input gating signals. The gating cycles were selected based on long beam-on and short beam-off times, short beam-on and long beam-off times, or equal beam on and off times to check linac performance. The beam latencies were measured as the time difference between the logic high gating signal and the first or last target pulses with an oscilloscope. Tissue-Phantom Ratio, beam flatness, and dose distributions from 5 different plans were measured using the 6 different gating durations and the un-gated irradiation. A PTW 729 2-D array was used to compare 5 plans versus the un-gated delivery with a 1%/1mm gamma index passing criteria. Results: The beam latencies of the linac were based off of 20 samples for beam-on and beam-off, for each gating cycle. The average beam-on delays were measured to be between 57 and 66msec, with a maximum of 88 msec. The beam off latencies averaged between 19 and 26msec, with a maximum of 48 msec. TPR20,10 measurements showed beam energy stability within 0.5% of the un-gated delivery. Beam flatness was better than 2.5% for all gated cycles. All but two deliveries, the open field with 4 seconds on, 1 second off, and a five field IMRT plan with 0.5 seconds on, 2.5 seconds off, had >90% passing rate. Conclusion: TrueBeam demonstrates excellent beam stability with minimal beam latencies under external device-based gated operations. Dosimetric measurements show minimal variation in beam energy, flatness, and plan delivery. Authors are employees of Varian Medical Systems, Inc.

  20. Electrical Aversion Conditioning with Chronic Alcoholics

    Science.gov (United States)

    Vogler, Roger E.; And Others

    1970-01-01

    Pseudoconditioning (random shock delivery), sham conditioning (no shock), and ward controls (routine hospital treatment) ( were compared with two conditioning groups. Conditioning only (contingent shock) and booster Ss (additional conditioning sessions after release from hospital) were shocked for drinking and reinforced by shock termination for…

  1. Topical and transdermal drug delivery: principles and practice

    National Research Council Canada - National Science Library

    Benson, Heather A. E; Watkinson, Adam C

    2012-01-01

    .... Providing an overview of the current science in drug and cosmetic application to and through the skin, Topical and Transdermal Drug Delivery includes treatment of skin conditions, skin permeation...

  2. Automatic coding method of the ACR Code

    International Nuclear Information System (INIS)

    Park, Kwi Ae; Ihm, Jong Sool; Ahn, Woo Hyun; Baik, Seung Kook; Choi, Han Yong; Kim, Bong Gi

    1993-01-01

    The authors developed a computer program for automatic coding of ACR(American College of Radiology) code. The automatic coding of the ACR code is essential for computerization of the data in the department of radiology. This program was written in foxbase language and has been used for automatic coding of diagnosis in the Department of Radiology, Wallace Memorial Baptist since May 1992. The ACR dictionary files consisted of 11 files, one for the organ code and the others for the pathology code. The organ code was obtained by typing organ name or code number itself among the upper and lower level codes of the selected one that were simultaneous displayed on the screen. According to the first number of the selected organ code, the corresponding pathology code file was chosen automatically. By the similar fashion of organ code selection, the proper pathologic dode was obtained. An example of obtained ACR code is '131.3661'. This procedure was reproducible regardless of the number of fields of data. Because this program was written in 'User's Defined Function' from, decoding of the stored ACR code was achieved by this same program and incorporation of this program into program in to another data processing was possible. This program had merits of simple operation, accurate and detail coding, and easy adjustment for another program. Therefore, this program can be used for automation of routine work in the department of radiology

  3. APR1400 Containment Simulation with CONTAIN code

    Energy Technology Data Exchange (ETDEWEB)

    Hwang, Moon Kyu; Chung, Bub Dong [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2010-05-15

    The more realistic containment pressure variation predicted by the CONTAIN code through the coupled analysis during a large break loss of coolant accident in the nuclear power plant is expected to provide more accurate prediction for the plant behavior than a standalone MARS-KS calculation. The input deck has been generated based on the already available ARP- 1400 input for CONTEMPT code. Similarly to the CONTEMPT input deck, a simple two-cell model was adopted to model the containment behavior, one cell for the containment inner volume and another cell for the environment condition. The developed input for the CONTAIN code is to be eventually applied for the coupled code calculation of MARS-KS/CONTAIN

  4. APR1400 Containment Simulation with CONTAIN code

    International Nuclear Information System (INIS)

    Hwang, Moon Kyu; Chung, Bub Dong

    2010-01-01

    The more realistic containment pressure variation predicted by the CONTAIN code through the coupled analysis during a large break loss of coolant accident in the nuclear power plant is expected to provide more accurate prediction for the plant behavior than a standalone MARS-KS calculation. The input deck has been generated based on the already available ARP- 1400 input for CONTEMPT code. Similarly to the CONTEMPT input deck, a simple two-cell model was adopted to model the containment behavior, one cell for the containment inner volume and another cell for the environment condition. The developed input for the CONTAIN code is to be eventually applied for the coupled code calculation of MARS-KS/CONTAIN

  5. Redesigning Care Delivery with Patient Support Personnel: Learning from Accountable Care Organizations

    Science.gov (United States)

    Gorbenko, Ksenia O.; Fraze, Taressa; Lewis, Valerie A.

    2017-01-01

    INTRODUCTION Accountable care organizations (ACOs) are a value-based payment model in the United States rooted in holding groups of healthcare providers financially accountable for the quality and total cost of care of their attributed population. To succeed in reaching their quality and efficiency goals, ACOs implement a variety of care delivery changes, including workforce redesign. Patient support personnel (PSP)—non-physician staff such as care coordinators, community health workers, and others—are critical to restructuring care delivery. Little is known about how ACOs are redesigning their patient support personnel in terms of responsibilities, location, and evaluation. METHODS We conducted semi-structured one-hour interviews with 25 executives at 16 distinct ACOs. The interviews were recorded, transcribed, and coded for themes, using a qualitative coding and analysis process. RESULTS ACOs deployed PSP to perform four clusters of responsibilities: care provision, care coordination, logistical help with transportation, and social and emotional support. ACOs deployed these personnel strategically across settings (primary care, inpatient services, emergency department, home care and community) depending on their population needs. Most ACOs used personnel with the same level of training across settings. Few ACOs planned to conduct a comprehensive evaluation of their PSP to optimize their value. DISCUSSION ACO strategies in workforce redesign indicate a shift from a physician-centered to a team-based approach. Employing personnel with varying levels of clinical training to perform different tasks can help further optimize care delivery. More robust evaluation of the deployment of PSP and their performance is needed to demonstrate cost-saving benefits of workforce redesign. PMID:28217305

  6. Improvement of blow down model for LEAP code

    International Nuclear Information System (INIS)

    Itooka, Satoshi; Fujimata, Kazuhiro

    2003-03-01

    In Japan Nuclear Cycle Development Institute, the improvement of analysis method for overheating tube rapture was studied for the accident of sodium-water reactions in the steam generator of a fast breeder reactor and the evaluation of heat transfer condition in the tube were carried out based on study of critical heat flux (CHF) and post-CHF heat transfer equation in Light Water Reactors. In this study, the improvement of blow down model for the LEAP code was carried out taking into consideration the above-mentioned evaluation of heat transfer condition. Improvements of the LEAP code were following items. Calculations and verification were performed with the improved LEAP code in order to confirm the code functions. The addition of critical heat flux (CHF) by the formula of Katto and the formula of Tong. The addition of post-CHF heat transfer equation by the formula of Condie-BengstonIV and the formula of Groeneveld 5.9. The physical properties of the water and steam are expanded to the critical conditions of the water. The expansion of the total number of section and the improvement of the input form. The addition of the function to control the valve setting by the PID control model. (author)

  7. Maximum Likelihood Blind Channel Estimation for Space-Time Coding Systems

    Directory of Open Access Journals (Sweden)

    Hakan A. Çırpan

    2002-05-01

    Full Text Available Sophisticated signal processing techniques have to be developed for capacity enhancement of future wireless communication systems. In recent years, space-time coding is proposed to provide significant capacity gains over the traditional communication systems in fading wireless channels. Space-time codes are obtained by combining channel coding, modulation, transmit diversity, and optional receive diversity in order to provide diversity at the receiver and coding gain without sacrificing the bandwidth. In this paper, we consider the problem of blind estimation of space-time coded signals along with the channel parameters. Both conditional and unconditional maximum likelihood approaches are developed and iterative solutions are proposed. The conditional maximum likelihood algorithm is based on iterative least squares with projection whereas the unconditional maximum likelihood approach is developed by means of finite state Markov process modelling. The performance analysis issues of the proposed methods are studied. Finally, some simulation results are presented.

  8. Development, validation and application of NAFA 2D-CFD code

    International Nuclear Information System (INIS)

    Vaidya, A.M.; Maheshwari, N.K.; Vijayan, P.K.; Saha, D.

    2010-01-01

    A 2D axi-symmetric code named NAFA (Version 1.0) is developed for studying the pipe flow under various conditions. It can handle laminar/ turbulent flows, with or without heat transfer, under sub-critical/super-critical conditions. The code solves for momentum, energy equations with standard k-ε turbulence model (with standard wall functions). It solves pipe flow subjected to 'velocity inlet', 'wall', 'axis' and 'pressure outlet' boundary conditions. It is validated for several cases by comparing its results with experimental data/analytical solutions/correlations. The code has excellent convergence characteristics as verified from fall of equation residual in each case. It has proven capability of generating mesh independent results for laminar as well as turbulent flows. The code is applied to supercritical flows. For supercritical flows, the effect of mesh size on prediction of heat transfer coefficient is studied. With grid refinement, the Y + reduces and reaches the limiting value of 11.63. Hence the accuracy is found to increase with grid refinement. NAFA is able to qualitatively predict the effect of heat flux and operating pressure on heat transfer coefficient. The heat transfer coefficient matches well with experimental values under various conditions. (author)

  9. [Reflection around the code of ethics for nurses].

    Science.gov (United States)

    Depoire, Nathalie

    2017-09-01

    The code of ethics for nurses highlights the values, principles and obligations which characterise our profession. It also emphasises the conditions required to enable nurses to perform their professional practice with the autonomy granted to them by the Public Health Code. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  10. QOS-aware error recovery in wireless body sensor networks using adaptive network coding.

    Science.gov (United States)

    Razzaque, Mohammad Abdur; Javadi, Saeideh S; Coulibaly, Yahaya; Hira, Muta Tah

    2014-12-29

    Wireless body sensor networks (WBSNs) for healthcare and medical applications are real-time and life-critical infrastructures, which require a strict guarantee of quality of service (QoS), in terms of latency, error rate and reliability. Considering the criticality of healthcare and medical applications, WBSNs need to fulfill users/applications and the corresponding network's QoS requirements. For instance, for a real-time application to support on-time data delivery, a WBSN needs to guarantee a constrained delay at the network level. A network coding-based error recovery mechanism is an emerging mechanism that can be used in these systems to support QoS at very low energy, memory and hardware cost. However, in dynamic network environments and user requirements, the original non-adaptive version of network coding fails to support some of the network and user QoS requirements. This work explores the QoS requirements of WBSNs in both perspectives of QoS. Based on these requirements, this paper proposes an adaptive network coding-based, QoS-aware error recovery mechanism for WBSNs. It utilizes network-level and user-/application-level information to make it adaptive in both contexts. Thus, it provides improved QoS support adaptively in terms of reliability, energy efficiency and delay. Simulation results show the potential of the proposed mechanism in terms of adaptability, reliability, real-time data delivery and network lifetime compared to its counterparts.

  11. Linear and nonlinear verification of gyrokinetic microstability codes

    Science.gov (United States)

    Bravenec, R. V.; Candy, J.; Barnes, M.; Holland, C.

    2011-12-01

    Verification of nonlinear microstability codes is a necessary step before comparisons or predictions of turbulent transport in toroidal devices can be justified. By verification we mean demonstrating that a code correctly solves the mathematical model upon which it is based. Some degree of verification can be accomplished indirectly from analytical instability threshold conditions, nonlinear saturation estimates, etc., for relatively simple plasmas. However, verification for experimentally relevant plasma conditions and physics is beyond the realm of analytical treatment and must rely on code-to-code comparisons, i.e., benchmarking. The premise is that the codes are verified for a given problem or set of parameters if they all agree within a specified tolerance. True verification requires comparisons for a number of plasma conditions, e.g., different devices, discharges, times, and radii. Running the codes and keeping track of linear and nonlinear inputs and results for all conditions could be prohibitive unless there was some degree of automation. We have written software to do just this and have formulated a metric for assessing agreement of nonlinear simulations. We present comparisons, both linear and nonlinear, between the gyrokinetic codes GYRO [J. Candy and R. E. Waltz, J. Comput. Phys. 186, 545 (2003)] and GS2 [W. Dorland, F. Jenko, M. Kotschenreuther, and B. N. Rogers, Phys. Rev. Lett. 85, 5579 (2000)]. We do so at the mid-radius for the same discharge as in earlier work [C. Holland, A. E. White, G. R. McKee, M. W. Shafer, J. Candy, R. E. Waltz, L. Schmitz, and G. R. Tynan, Phys. Plasmas 16, 052301 (2009)]. The comparisons include electromagnetic fluctuations, passing and trapped electrons, plasma shaping, one kinetic impurity, and finite Debye-length effects. Results neglecting and including electron collisions (Lorentz model) are presented. We find that the linear frequencies with or without collisions agree well between codes, as do the time averages of

  12. Delivery presentations

    Science.gov (United States)

    Pregnancy - delivery presentation; Labor - delivery presentation; Occiput posterior; Occiput anterior; Brow presentation ... The mother can walk, rock, and try different delivery positions during labor to help encourage the baby ...

  13. Large-Scale Analysis of Remote Code Injection Attacks in Android Apps

    Directory of Open Access Journals (Sweden)

    Hyunwoo Choi

    2018-01-01

    Full Text Available It is pretty well known that insecure code updating procedures for Android allow remote code injection attack. However, other than codes, there are many resources in Android that have to be updated, such as temporary files, images, databases, and configurations (XML and JSON. Security of update procedures for these resources is largely unknown. This paper investigates general conditions for remote code injection attacks on these resources. Using this, we design and implement a static detection tool that automatically identifies apps that meet these conditions. We apply the detection tool to a large dataset comprising 9,054 apps, from three different types of datasets: official market, third-party market, and preinstalled apps. As a result, 97 apps were found to be potentially vulnerable, with 53 confirmed as vulnerable to remote code injection attacks.

  14. Coding in pigeons: Multiple-coding versus single-code/default strategies.

    Science.gov (United States)

    Pinto, Carlos; Machado, Armando

    2015-05-01

    To investigate the coding strategies that pigeons may use in a temporal discrimination tasks, pigeons were trained on a matching-to-sample procedure with three sample durations (2s, 6s and 18s) and two comparisons (red and green hues). One comparison was correct following 2-s samples and the other was correct following both 6-s and 18-s samples. Tests were then run to contrast the predictions of two hypotheses concerning the pigeons' coding strategies, the multiple-coding and the single-code/default. According to the multiple-coding hypothesis, three response rules are acquired, one for each sample. According to the single-code/default hypothesis, only two response rules are acquired, one for the 2-s sample and a "default" rule for any other duration. In retention interval tests, pigeons preferred the "default" key, a result predicted by the single-code/default hypothesis. In no-sample tests, pigeons preferred the key associated with the 2-s sample, a result predicted by multiple-coding. Finally, in generalization tests, when the sample duration equaled 3.5s, the geometric mean of 2s and 6s, pigeons preferred the key associated with the 6-s and 18-s samples, a result predicted by the single-code/default hypothesis. The pattern of results suggests the need for models that take into account multiple sources of stimulus control. © Society for the Experimental Analysis of Behavior.

  15. Electronic health record standards, coding systems, frameworks, and infrastructures

    CERN Document Server

    Sinha, Pradeep K; Bendale, Prashant; Mantri, Manisha; Dande, Atreya

    2013-01-01

    Discover How Electronic Health Records Are Built to Drive the Next Generation of Healthcare Delivery The increased role of IT in the healthcare sector has led to the coining of a new phrase ""health informatics,"" which deals with the use of IT for better healthcare services. Health informatics applications often involve maintaining the health records of individuals, in digital form, which is referred to as an Electronic Health Record (EHR). Building and implementing an EHR infrastructure requires an understanding of healthcare standards, coding systems, and frameworks. This book provides an

  16. Mathematic preprocessor for RELAP5 code using Microsoft Excel

    International Nuclear Information System (INIS)

    Paladino, Patricia Andrea

    2006-01-01

    Computational program are used for thermal hydraulic analysis of accidents and transients conditions in nuclear power plants. The RELAP5 code has been developed to simulate accidents and transients conditions, performing a best estimate analysis, in Pressurized Water Reactors (PWR) and auxiliary systems. The RELAP5 code, which has been used as a toll for licensing nuclear facilities in Brazil, is the objective of the study performed in this work. The main problem in using the RELAP5 code is the huge amount of information necessary to model the nuclear reactor and thus to simulate thermal-hydraulic accidents. Moreover, the RELAP5 code input data requires a large amount of mathematical operations to calculate the geometry of the plant components. Therefore, in order to make easier the data input for the RELAP5 code a friendly preprocessor has been developed. The preprocessor accepts basic information about the geometry of the plant components and performs all the calculations needed for the RELAP5 input. This preprocessor has been developed based on the MS-Excel software. (author)

  17. Consent Codes: Upholding Standard Data Use Conditions.

    Directory of Open Access Journals (Sweden)

    Stephanie O M Dyke

    2016-01-01

    Full Text Available A systematic way of recording data use conditions that are based on consent permissions as found in the datasets of the main public genome archives (NCBI dbGaP and EMBL-EBI/CRG EGA.

  18. Analysis of fuel pin behavior under slow-ramp type transient overpower condition by using the fuel performance evaluation code 'FEMAXI-FBR'

    International Nuclear Information System (INIS)

    Tsuboi, Yasushi; Ninokata, Hisashi; Endo, Hiroshi; Ishizu, Tomoko; Tatewaki, Isao; Saito, Hiroaki

    2012-01-01

    FEMAXI-FBR has been developed as the one module of the core disruptive accident analysis code 'ASTERIA-FBR' in order to evaluate the mixed oxide (MOX) fuel performance under steady, transient and accident conditions of fast reactors consistently. On the basis of light water reactor (LWR) fuel performance evaluation code 'FEMAXI-6', FEMAXI-FBR develops specific models for the fast reactor fuel performance, such as restructuring, material migration during steady state and transient, melting cavity formation and pressure during accident, so that it can evaluate the fuel failure during accident. The analysis of test pin with slow transient over power test of CABRI-2 program was conducted from steady to transient. The test pin was pre-irradiated and tested under transient overpower with several % P 0 /s (P 0 : steady state power) of the power rate. Analysis results of the gas release ratio, pin failure time, and fuel melt radius were compared to measured values. The analysis results of the steady and transient performances were also compared with the measured values. The compared performances are gas release ratio, fuel restructuring for steady state and linear power and melt radius at failure during transient. This analysis result reproduces the measured value. It was concluded that FEMAXI-FBR is effective to evaluate fast reactor fuel performances from steady state to accident conditions. (author)

  19. Change in MS-DRG assignment and hospital reimbursement as a result of Centers for Medicare & Medicaid changes in payment for hospital-acquired conditions: is it coding or quality?

    Science.gov (United States)

    McNutt, Robert; Johnson, Tricia J; Odwazny, Richard; Remmich, Zachary; Skarupski, Kimberly; Meurer, Steven; Hohmann, Samuel; Harting, Brian

    2010-01-01

    In October 2008, the Centers for Medicare & Medicaid Services reduced payments to hospitals for a group of hospital-acquired conditions (HACs) not documented as present on admission (POA). It is unknown what proportion of Medicare severity diagnosis related group (MS-DRG) assignments will change when the International Classification of Disease, 9th Revision, Clinical Modification (ICD-9-CM) diagnosis code for the HAC is not taken into account even before considering the POA status. The primary objectives were to estimate the proportion of cases that change MS-DRG assignment when HACs are removed from the calculation, the subsequent changes in reimbursement to hospitals, and the attenuation in changes in MS-DRG assignment after factoring in those that may be POA. Last, we explored the effect of the numbers of ICD-9-CM diagnosis codes on MS-DRG assignment. We obtained 2 years of discharge data from academic medical centers that were members of the University Health System Consortium and identified all cases with 1 of 7 HACs coded through ICD-9-CM diagnosis codes. We calculated the MS-DRG for each case with and without the HAC and, hence, the proportion where MS-DRG assignment changed. Next, we used a bootstrap method to calculate the range in the proportion of cases changing assignment to account for POA status. Changes in reimbursement were estimated by using the 2008 MS-DRG weights payment formula. Of 184,932 cases with at least 1 HAC, 27.6% (n = 52,272) would experience a change in MS-DRG assignment without the HAC factored into the assignment. After taking into account those conditions that were potentially POA, 7.5% (n = 14,176) of the original cases would change MS-DRG assignment, with an average loss in reimbursement per case ranging from $1548 with a catheter-associated urinary tract infection to $7310 for a surgical site infection. These reductions would translate into a total reimbursement loss of $50 261,692 (range: $38 330,747-$62 344,360) for the 86

  20. Lossless, Near-Lossless, and Refinement Coding of Bi-level Images

    DEFF Research Database (Denmark)

    Martins, Bo; Forchhammer, Søren Otto

    1999-01-01

    We present general and unified algorithms for lossy/lossless coding of bi-level images. The compression is realized by applying arithmetic coding to conditional probabilities. As in the current JBIG standard the conditioning may be specified by a template.For better compression, the more general...... to the specialized soft pattern matching techniques which work better for text. Template based refinement coding is applied for lossy-to-lossless refinement. Introducing only a small amount of loss in halftoned test images, compression is increased by up to a factor of four compared with JBIG. Lossy, lossless......, and refinement decoding speed and lossless encoding speed are less than a factor of two slower than JBIG. The (de)coding method is proposed as part of JBIG2, an emerging international standard for lossless/lossy compression of bi-level images....

  1. On entanglement-assisted quantum codes achieving the entanglement-assisted Griesmer bound

    Science.gov (United States)

    Li, Ruihu; Li, Xueliang; Guo, Luobin

    2015-12-01

    The theory of entanglement-assisted quantum error-correcting codes (EAQECCs) is a generalization of the standard stabilizer formalism. Any quaternary (or binary) linear code can be used to construct EAQECCs under the entanglement-assisted (EA) formalism. We derive an EA-Griesmer bound for linear EAQECCs, which is a quantum analog of the Griesmer bound for classical codes. This EA-Griesmer bound is tighter than known bounds for EAQECCs in the literature. For a given quaternary linear code {C}, we show that the parameters of the EAQECC that EA-stabilized by the dual of {C} can be determined by a zero radical quaternary code induced from {C}, and a necessary condition under which a linear EAQECC may achieve the EA-Griesmer bound is also presented. We construct four families of optimal EAQECCs and then show the necessary condition for existence of EAQECCs is also sufficient for some low-dimensional linear EAQECCs. The four families of optimal EAQECCs are degenerate codes and go beyond earlier constructions. What is more, except four codes, our [[n,k,d_{ea};c

  2. A method for modeling co-occurrence propensity of clinical codes with application to ICD-10-PCS auto-coding.

    Science.gov (United States)

    Subotin, Michael; Davis, Anthony R

    2016-09-01

    Natural language processing methods for medical auto-coding, or automatic generation of medical billing codes from electronic health records, generally assign each code independently of the others. They may thus assign codes for closely related procedures or diagnoses to the same document, even when they do not tend to occur together in practice, simply because the right choice can be difficult to infer from the clinical narrative. We propose a method that injects awareness of the propensities for code co-occurrence into this process. First, a model is trained to estimate the conditional probability that one code is assigned by a human coder, given than another code is known to have been assigned to the same document. Then, at runtime, an iterative algorithm is used to apply this model to the output of an existing statistical auto-coder to modify the confidence scores of the codes. We tested this method in combination with a primary auto-coder for International Statistical Classification of Diseases-10 procedure codes, achieving a 12% relative improvement in F-score over the primary auto-coder baseline. The proposed method can be used, with appropriate features, in combination with any auto-coder that generates codes with different levels of confidence. The promising results obtained for International Statistical Classification of Diseases-10 procedure codes suggest that the proposed method may have wider applications in auto-coding. © The Author 2016. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  3. FRAPTRAN Fuel Rod Code and its Coupled Transient Analysis with the GENFLO Thermal-Hydraulic Code

    International Nuclear Information System (INIS)

    Valtonen, Keijo; Hamalainen, Anitta; Cunningham, Mitchel E.

    2002-01-01

    The FRAPTRAN computer code has been developed for the U.S. Nuclear Regulatory Commission (NRC) to calculate fuel behavior during power and/or cooling transients at burnup levels up to 65 MWd/kgM. FRAPTRAN has now been assessed and peer reviewed. STUK/VTT have coupled GENFLO to FRAPTRAN for calculations with improved coolant boundary conditions and prepared example calculations to show the effect of improving the coolant boundary conditions.

  4. FRAPTRAN Fuel Rod Code and its Coupled Transient Analysis with the GENFLO Thermal-Hydraulic Code

    Energy Technology Data Exchange (ETDEWEB)

    Valtonen, Keijo (Radiation and Nuclear Safety Authority, Finland); Hamalainen, Anitta (VTT Energy, Finland); Cunningham, Mitchel E.(BATTELLE (PACIFIC NW LAB))

    2002-05-01

    The FRAPTRAN computer code has been developed for the U.S. Nuclear Regulatory Commission (NRC) to calculate fuel behavior during power and/or cooling transients at burnup levels up to 65 MWd/kgM. FRAPTRAN has now been assessed and peer reviewed. STUK/VTT have coupled GENFLO to FRAPTRAN for calculations with improved coolant boundary conditions and prepared example calculations to show the effect of improving the coolant boundary conditions.

  5. Light water reactor fuel analysis code FEMAXI-7; model and structure

    International Nuclear Information System (INIS)

    Suzuki, Motoe; Udagawa, Yutaka; Saitou, Hiroaki

    2011-03-01

    A light water reactor fuel analysis code FEMAXI-7 has been developed for the purpose of analyzing the fuel behavior in both normal conditions and anticipated transient conditions. This code is an advanced version which has been produced by incorporating the former version FEMAXI-6 with numerous functional improvements and extensions. In FEMAXI-7, many new models have been added and parameters have been clearly arranged. Also, to facilitate effective maintenance and accessibility of the code, modularization of subroutines and functions have been attained, and quality comment descriptions of variables or physical quantities have been incorporated in the source code. With these advancements, the FEMAXI-7 code has been upgraded to a versatile analytical tool for high burnup fuel behavior analyses. This report describes in detail the design, basic theory and structure, models and numerical method, and improvements and extensions. (author)

  6. General Labour Code (Act No. 2 of 1986), 5 April 1986. [Selected provisions].

    Science.gov (United States)

    1989-01-01

    Guinea-Bissau's General Labor Code, Act No. 2 of 1986, requires that employers adopt non-discriminatory procedures in dealing with their employees, disallowing discrimination based on gender, race, national origin, religion, political ideology or inclination, or on whether or not an employee is affiliated to a worker's union. Women are guaranteed equality with men in work opportunity and employment treatment; they are assured access to any type of job, profession, or position which does not pose any potential or actual threat to their genetic functioning. Additional legislation shall establish the conditions and prohibitions for contracting woman for heavy labor, for jobs performed under insalubrious conditions, for underground work, and for other types of jobs which might endanger a woman's genetic functioning. Job offers must not discriminate, unless the restrictions or specifications are essential to the nature of the job, rendering the job qualitatively differentiable when performed by a man or a woman. The employer must ensure that female workers have the same job opportunity and treatment for professional training and career development. Different specific job categories may not be created for men and women if a woman's salary is inferior to that of a man performing equivalent work in a corresponding professional category. Protection during pregnancy and delivery guarantees a woman the right to decline medically inadvisable tasks without loss of wages; to decline overtime work; to be absent from work when necessary for maternal medical care without loss of wages; to interrupt daily work to nurse her children for 1 hour or 2 for half-hour periods for up to 1 year without the loss of wages. Every female employee has the right to 60 days pregnancy and maternity leave, without loss of wages, for whatever clinical type of delivery, including for still births and for births where the infant died shortly thereafter.

  7. Evaluation Codes from an Affine Veriety Code Perspective

    DEFF Research Database (Denmark)

    Geil, Hans Olav

    2008-01-01

    Evaluation codes (also called order domain codes) are traditionally introduced as generalized one-point geometric Goppa codes. In the present paper we will give a new point of view on evaluation codes by introducing them instead as particular nice examples of affine variety codes. Our study...... includes a reformulation of the usual methods to estimate the minimum distances of evaluation codes into the setting of affine variety codes. Finally we describe the connection to the theory of one-pointgeometric Goppa codes. Contents 4.1 Introduction...... . . . . . . . . . . . . . . . . . . . . . . . 171 4.9 Codes form order domains . . . . . . . . . . . . . . . . . . . . . . . . . . . . 173 4.10 One-point geometric Goppa codes . . . . . . . . . . . . . . . . . . . . . . . . 176 4.11 Bibliographical Notes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 178 References...

  8. 76 FR 36231 - American Society of Mechanical Engineers (ASME) Codes and New and Revised ASME Code Cases

    Science.gov (United States)

    2011-06-21

    ...The NRC is amending its regulations to incorporate by reference the 2005 Addenda (July 1, 2005) and 2006 Addenda (July 1, 2006) to the 2004 ASME Boiler and Pressure Vessel Code, Section III, Division 1; 2007 ASME Boiler and Pressure Vessel Code, Section III, Division 1, 2007 Edition (July 1, 2007), with 2008a Addenda (July 1, 2008); 2005 Addenda (July 1, 2005) and 2006 Addenda (July 1, 2006) to the 2004 ASME Boiler and Pressure Vessel Code, Section XI, Division 1; 2007 ASME Boiler and Pressure Vessel Code, Section XI, Division 1, 2007 Edition (July 1, 2007), with 2008a Addenda (July 1, 2008); and 2005 Addenda, ASME OMa Code-2005 (approved July 8, 2005) and 2006 Addenda, ASME OMb Code-2006 (approved July 6, 2006) to the 2004 ASME Code for Operation and Maintenance of Nuclear Power Plants (OM Code). The NRC is also incorporating by reference (with conditions on their use) ASME Boiler and Pressure Vessel Code Case N-722-1, ``Additional Examinations for PWR Pressure Retaining Welds in Class 1 Components Fabricated with Alloy 600/82/182 Materials, Section XI, Division 1,'' Supplement 8, ASME approval date: January 26, 2009, and ASME Boiler and Pressure Vessel Code Case N-770-1, ``Alternative Examination Requirements and Acceptance Standards for Class 1 PWR Piping and Vessel Nozzle Butt Welds Fabricated With UNS N06082 or UNS W86182 Weld Filler Material With or Without Application of Listed Mitigation Activities, Section XI, Division 1,'' ASME approval date: December 25, 2009.

  9. Esophageal function testing: Billing and coding update.

    Science.gov (United States)

    Khan, A; Massey, B; Rao, S; Pandolfino, J

    2018-01-01

    Esophageal function testing is being increasingly utilized in diagnosis and management of esophageal disorders. There have been several recent technological advances in the field to allow practitioners the ability to more accurately assess and treat such conditions, but there has been a relative lack of education in the literature regarding the associated Common Procedural Terminology (CPT) codes and methods of reimbursement. This review, commissioned and supported by the American Neurogastroenterology and Motility Society Council, aims to summarize each of the CPT codes for esophageal function testing and show the trends of associated reimbursement, as well as recommend coding methods in a practical context. We also aim to encourage many of these codes to be reviewed on a gastrointestinal (GI) societal level, by providing evidence of both discrepancies in coding definitions and inadequate reimbursement in this new era of esophageal function testing. © 2017 John Wiley & Sons Ltd.

  10. Transdermal drug delivery

    Science.gov (United States)

    Prausnitz, Mark R.; Langer, Robert

    2009-01-01

    Transdermal drug delivery has made an important contribution to medical practice, but has yet to fully achieve its potential as an alternative to oral delivery and hypodermic injections. First-generation transdermal delivery systems have continued their steady increase in clinical use for delivery of small, lipophilic, low-dose drugs. Second-generation delivery systems using chemical enhancers, non-cavitational ultrasound and iontophoresis have also resulted in clinical products; the ability of iontophoresis to control delivery rates in real time provides added functionality. Third-generation delivery systems target their effects to skin’s barrier layer of stratum corneum using microneedles, thermal ablation, microdermabrasion, electroporation and cavitational ultrasound. Microneedles and thermal ablation are currently progressing through clinical trials for delivery of macromolecules and vaccines, such as insulin, parathyroid hormone and influenza vaccine. Using these novel second- and third-generation enhancement strategies, transdermal delivery is poised to significantly increase impact on medicine. PMID:18997767

  11. Independent validation testing of the FLAME computer code, Version 1.0

    International Nuclear Information System (INIS)

    Martian, P.; Chung, J.N.

    1992-07-01

    Independent testing of the FLAME computer code, Version 1.0, was conducted to determine if the code is ready for use in hydrological and environmental studies at Department of Energy sites. This report describes the technical basis, approach, and results of this testing. Validation tests, (i.e., tests which compare field data to the computer generated solutions) were used to determine the operational status of the FLAME computer code and were done on a qualitative basis through graphical comparisons of the experimental and numerical data. These tests were specifically designed to check: (1) correctness of the FORTRAN coding, (2) computational accuracy, and (3) suitability to simulating actual hydrologic conditions. This testing was performed using a structured evaluation protocol which consisted of: (1) independent applications, and (2) graduated difficulty of test cases. Three tests ranging in complexity from simple one-dimensional steady-state flow field problems under near-saturated conditions to two-dimensional transient flow problems with very dry initial conditions

  12. Repeat cesarean delivery: what indications are recorded in the medical chart?

    Science.gov (United States)

    Lydon-Rochelle, Mona T; Gardella, Carolyn; Cárdenas, Vicky; Easterling, Thomas R

    2006-03-01

    National surveillance estimates reported a troubling 63 percent decline in the rate of vaginal birth after cesarean delivery (VBAC) from 1996 (28.3%) to 2003 (10.6%), with subsequent rising rates of repeat cesarean delivery. The study objective was to examine patterns of documented indications for repeat cesarean delivery in women with and without labor. We conducted a population-based validation study of 19 nonfederal short-stay hospitals in Washington state. Of the 4,541 women who had live births in 2000, 11 percent (n = 493) had repeat cesarean without labor and 3 percent (n = 138) had repeat cesarean with labor. Incidence of medical conditions and pregnancy complications, patterns of documented indications for repeat cesarean delivery, and perioperative complications in relation to repeat cesarean delivery with and without labor were calculated. Of the 493 women who underwent a repeat cesarean delivery without labor, "elective"(36%) and "maternal request"(18%) were the most common indications. Indications for maternal medical conditions (3.0%) were uncommon. Among the 138 women with repeat cesarean delivery with labor, 60.1 percent had failure to progress, 24.6 percent a non-reassuring fetal heart rate, 8.0 percent cephalopelvic disproportion, and 7.2 percent maternal request during labor. Fetal indications were less common (5.8%). Breech, failed vacuum, abruptio placentae, maternal complications, and failed forceps were all indicated less than 5.0 percent. Women's perioperative complications did not vary significantly between women without and with labor. Regardless of a woman's labor status, nearly 10 percent of women with repeat cesarean delivery had no documented indication as to why a cesarean delivery was performed. "Elective" and "maternal request" were common indications among women undergoing repeat cesarean delivery without labor, and nearly 10 percent of women had undocumented indications for repeat cesarean delivery in their medical record

  13. Regional TEC model under quiet geomagnetic conditions and low-to-moderate solar activity based on CODE GIMs

    Science.gov (United States)

    Feng, Jiandi; Jiang, Weiping; Wang, Zhengtao; Zhao, Zhenzhen; Nie, Linjuan

    2017-08-01

    Global empirical total electron content (TEC) models based on TEC maps effectively describe the average behavior of the ionosphere. However, the accuracy of these global models for a certain region may not be ideal. Due to the number and distribution of the International GNSS Service (IGS) stations, the accuracy of TEC maps is geographically different. The modeling database derived from the global TEC maps with different accuracy is likely one of the main reasons that limits the accuracy of the new models. Moreover, many anomalies in the ionosphere are geographic or geomagnetic dependent, and as such the accuracy of global models can deteriorate if these anomalies are not fully incorporated into the modeling approach. For regional models built in small areas, these influences on modeling are immensely weakened. Thus, the regional TEC models may better reflect the temporal and spatial variations of TEC. In our previous work (Feng et al., 2016), a regional TEC model TECM-NEC is proposed for northeast China. However, this model is only directed against the typical region of Mid-latitude Summer Nighttime Anomaly (MSNA) occurrence, which is meaningless in other regions without MSNA. Following the technique of TECM-NEC model, this study proposes another regional empirical TEC model for other regions in mid-latitudes. Taking a small area BeiJing-TianJin-Tangshan (JJT) region (37.5°-42.5° N, 115°-120° E) in China as an example, a regional empirical TEC model (TECM-JJT) is proposed using the TEC grid data from January 1, 1999 to June 30, 2015 provided by the Center for Orbit Determination in Europe (CODE) under quiet geomagnetic conditions. The TECM-JJT model fits the input CODE TEC data with a bias of 0.11TECU and a root mean square error of 3.26TECU. Result shows that the regional model TECM-JJT is consistent with CODE TEC data and GPS-TEC data.

  14. The modeling of fuel rod behaviour under RIA conditions in the code DYN3D

    International Nuclear Information System (INIS)

    Rohde, U.

    2001-01-01

    A description of the fuel rod behaviour and heat transfer model used in the code DYN3D for nuclear reactor core dynamic simulations is given. Besides the solution of heat conduction equations in fuel and cladding, the model comprises a detailed description of heat transfer in the gas gap by conduction, radiation and fuel-cladding contact. The gas gap behaviour is modeled in a mechanistic way taking into account transient changes of the gas gap parameters based on given conditions for the initial state. Thermal, elastic and plastic deformations of fuel and cladding are taken into account within 1D approximation. A creeping law for time-dependent estimation of plastic deformations is implemented. Metal-water reaction of the cladding material in the high temperature region is considered. The cladding-coolant heat transfer regime map covers the region from one-phase liquid convection to dispersed flow with superheated steam. Special emphasis is put on taking into account the impact of thermodynamic non-equilibrium conditions on heat transfer. For the validation of the model, experiments on fuel rod behaviour during RIAs carried out in Russian and Japanese pulsed research reactors with shortened probes of fresh fuel rods are calculated. Comparisons between calculated and measured results are shown and discussed. It is shown, that the fuel rod behaviour is significantly influenced by plastic deformation of the cladding, post crisis heat transfer with sub-cooled liquid conditions and heat release from the metal-water reaction. Numerical studies concerning the fuel rod behaviour under RIA conditions in power reactors are reported on. It is demonstrated, that the fuel rod behaviour at high pressures and flow rates in power reactors is different from the behaviour under atmospheric pressure and stagnant flow conditions in the experiments. The mechanisms of fuel rod failure for fresh and burned fuel reported from the literature can be qualitatively reproduced by the DYN3D

  15. An Optimal Linear Coding for Index Coding Problem

    OpenAIRE

    Pezeshkpour, Pouya

    2015-01-01

    An optimal linear coding solution for index coding problem is established. Instead of network coding approach by focus on graph theoric and algebraic methods a linear coding program for solving both unicast and groupcast index coding problem is presented. The coding is proved to be the optimal solution from the linear perspective and can be easily utilize for any number of messages. The importance of this work is lying mostly on the usage of the presented coding in the groupcast index coding ...

  16. Application of the thermal-hydraulic codes in VVER-440 steam generators modelling

    Energy Technology Data Exchange (ETDEWEB)

    Matejovic, P.; Vranca, L.; Vaclav, E. [Nuclear Power Plant Research Inst. VUJE (Slovakia)

    1995-12-31

    Performances with the CATHARE2 V1.3U and RELAP5/MOD3.0 application to the VVER-440 SG modelling during normal conditions and during transient with secondary water lowering are described. Similar recirculation model was chosen for both codes. In the CATHARE calculation, no special measures were taken with the aim to optimize artificially flow rate distribution coefficients for the junction between SG riser and steam dome. Contrary to RELAP code, the CATHARE code is able to predict reasonable the secondary swell level in nominal conditions. Both codes are able to model properly natural phase separation on the SG water level. 6 refs.

  17. Application of the thermal-hydraulic codes in VVER-440 steam generators modelling

    Energy Technology Data Exchange (ETDEWEB)

    Matejovic, P; Vranca, L; Vaclav, E [Nuclear Power Plant Research Inst. VUJE (Slovakia)

    1996-12-31

    Performances with the CATHARE2 V1.3U and RELAP5/MOD3.0 application to the VVER-440 SG modelling during normal conditions and during transient with secondary water lowering are described. Similar recirculation model was chosen for both codes. In the CATHARE calculation, no special measures were taken with the aim to optimize artificially flow rate distribution coefficients for the junction between SG riser and steam dome. Contrary to RELAP code, the CATHARE code is able to predict reasonable the secondary swell level in nominal conditions. Both codes are able to model properly natural phase separation on the SG water level. 6 refs.

  18. [Evaluation of changes in the mode of twin deliveries over the years].

    Science.gov (United States)

    Madej, Anna; Szymusik, Iwona; Oledzka, Magdalena; Kosińska-Kaczyńska, Katarzyna; Bomba-Opoń, Dorota A; Wielgoś, Mirosław

    2012-10-01

    The aim of the study was to evaluate changes in the course of twin deliveries over the years, with particular emphasis on the history of infertility duration of pregnancy mode of delivery indications for caesarean section (CS) and infant condition. The study consisted of three groups of patients who delivered twins at the First Department of Obstetrics & Gynecology Medical University of Warsaw: 92 women in years 1987-1991 (G1), 62 in years 1997-2001 (G2) and 126 in years 2007-2010 (G3). The history of infertility treatment (especially in vitro fertilization), mode of delivery indications for cesarean section and newborn condition were taken into account. The results were afterwards compared among the groups and the differences were analyzed with the use of Statistica 10.0 software, with p value Manual maneuvers on the 2nd twins were applied in 25% vs. 6.5% vs. 0.79% of deliveries (pApgar scores of the first twins in the 1st and 5th minute of life among the studied groups. However, second twins were delivered in significantly better condition in G2 and G3 than in G1 (5-minute Apgar of 8-10 points: 79.7% vs. 93.3% vs. 92.6%; p<0.05). Twin pregnancy rate almost doubled over the years, mostly due to a growing popularity of the infertility treatment. Cesarean section is increasingly being chosen to deliver twins. The non-cephalic position of the 2nd fetus has become an important indication for cesarean section. Change in the mode of twin deliveries can be beneficial for the condition of the 2nd twin.

  19. Mucosal delivery of liposome-chitosan nanoparticle complexes.

    Science.gov (United States)

    Carvalho, Edison L S; Grenha, Ana; Remuñán-López, Carmen; Alonso, Maria José; Seijo, Begoña

    2009-01-01

    Designing adequate drug carriers has long been a major challenge for those working in drug delivery. Since drug delivery strategies have evolved for mucosal delivery as the outstanding alternative to parenteral administration, many new drug delivery systems have been developed which evidence promising properties to address specific issues. Colloidal carriers, such as nanoparticles and liposomes, have been referred to as the most valuable approaches, but still have some limitations that can become more inconvenient as a function of the specific characteristics of administration routes. To overcome these limitations, we developed a new drug delivery system that results from the combination of chitosan nanoparticles and liposomes, in an approach of combining their advantages, while avoiding their individual limitations. These lipid/chitosan nanoparticle complexes are, thus, expected to protect the encapsulated drug from harsh environmental conditions, while concomitantly providing its controlled release. To prepare these assemblies, two different strategies have been applied: one focusing on the simple hydration of a previously formed dry lipid film with a suspension of chitosan nanoparticles, and the other relying on the lyophilization of both basic structures (nanoparticles and liposomes) with a subsequent step of hydration with water. The developed systems are able to provide a controlled release of the encapsulated model peptide, insulin, evidencing release profiles that are dependent on their lipid composition. Moreover, satisfactory in vivo results have been obtained, confirming the potential of these newly developed drug delivery systems as drug carriers through distinct mucosal routes.

  20. Assisted Vaginal Delivery

    Science.gov (United States)

    ... Education & Events Advocacy For Patients About ACOG Assisted Vaginal Delivery Home For Patients Search FAQs Assisted Vaginal ... Vaginal Delivery FAQ192, February 2016 PDF Format Assisted Vaginal Delivery Labor, Delivery, and Postpartum Care What is ...

  1. QoS-Aware Error Recovery in Wireless Body Sensor Networks Using Adaptive Network Coding

    Directory of Open Access Journals (Sweden)

    Mohammad Abdur Razzaque

    2014-12-01

    Full Text Available Wireless body sensor networks (WBSNs for healthcare and medical applications are real-time and life-critical infrastructures, which require a strict guarantee of quality of service (QoS, in terms of latency, error rate and reliability. Considering the criticality of healthcare and medical applications, WBSNs need to fulfill users/applications and the corresponding network’s QoS requirements. For instance, for a real-time application to support on-time data delivery, a WBSN needs to guarantee a constrained delay at the network level. A network coding-based error recovery mechanism is an emerging mechanism that can be used in these systems to support QoS at very low energy, memory and hardware cost. However, in dynamic network environments and user requirements, the original non-adaptive version of network coding fails to support some of the network and user QoS requirements. This work explores the QoS requirements of WBSNs in both perspectives of QoS. Based on these requirements, this paper proposes an adaptive network coding-based, QoS-aware error recovery mechanism for WBSNs. It utilizes network-level and user-/application-level information to make it adaptive in both contexts. Thus, it provides improved QoS support adaptively in terms of reliability, energy efficiency and delay. Simulation results show the potential of the proposed mechanism in terms of adaptability, reliability, real-time data delivery and network lifetime compared to its counterparts.

  2. QoS-Aware Error Recovery in Wireless Body Sensor Networks Using Adaptive Network Coding

    Science.gov (United States)

    Razzaque, Mohammad Abdur; Javadi, Saeideh S.; Coulibaly, Yahaya; Hira, Muta Tah

    2015-01-01

    Wireless body sensor networks (WBSNs) for healthcare and medical applications are real-time and life-critical infrastructures, which require a strict guarantee of quality of service (QoS), in terms of latency, error rate and reliability. Considering the criticality of healthcare and medical applications, WBSNs need to fulfill users/applications and the corresponding network's QoS requirements. For instance, for a real-time application to support on-time data delivery, a WBSN needs to guarantee a constrained delay at the network level. A network coding-based error recovery mechanism is an emerging mechanism that can be used in these systems to support QoS at very low energy, memory and hardware cost. However, in dynamic network environments and user requirements, the original non-adaptive version of network coding fails to support some of the network and user QoS requirements. This work explores the QoS requirements of WBSNs in both perspectives of QoS. Based on these requirements, this paper proposes an adaptive network coding-based, QoS-aware error recovery mechanism for WBSNs. It utilizes network-level and user-/application-level information to make it adaptive in both contexts. Thus, it provides improved QoS support adaptively in terms of reliability, energy efficiency and delay. Simulation results show the potential of the proposed mechanism in terms of adaptability, reliability, real-time data delivery and network lifetime compared to its counterparts. PMID:25551485

  3. FUMACS-G, a Graphical User Interface for FUMACS Code Package

    International Nuclear Information System (INIS)

    Trontl, K.; Gergeta, K.; Smuc, T.

    2002-01-01

    The FUMACS (FUel MAnagement Code System) code package has been developed at Rudjer Boskovic Institute in year 1991 with the aim to enable in-core fuel management analysis of the NPP Krsko core for nominal conditions. Due to modernization and uprating of the NPP Krsko core in year 2000 and the original 1991 FUMACS inadequacy in simulating NPP Krsko core in these uprated conditions, in the year 2001 a new version of FUMACS code package has been developed - FUMACS/FEEC 2001. The code package upgrading procedure consisted of two main aspects: modifications of master files, libraries and codes necessary for proper modeling of the uprated NPP Krsko core and development of the code package structure suitable for Windows-32 environment. The latter included upgrading the source of the code from FORTRAN F77 to F90 level and development of a graphical, user-friendly interface with fully integrated electronic help system. Since the original FUMACS code package has been developed as a DOS based application, running of the code package on a Windows operating system proved to be rather inefficient and lacking in advantages of a standard Windows application. Therefore, FUMACS-G has been developed as a user friendly environment for handling off all project input and output files, as well as for easier overall project management. The design of FUMACS-G shell has been based on Microsoft application design guidelines. (author)

  4. Intracranial drug delivery for subarachnoid hemorrhage.

    Science.gov (United States)

    Macdonald, Robert Loch; Leung, Ming; Tice, Tom

    2012-01-01

    Tice and colleagues pioneered site-specific, sustained-release drug delivery to the brain almost 30 years ago. Currently there is one drug approved for use in this manner. Clinical trials in subarachnoid hemorrhage have led to approval of nimodipine for oral and intravenous use, but other drugs, such as clazosentan, hydroxymethylglutaryl CoA reductase inhibitors (statins) and magnesium, have not shown consistent clinical efficacy. We propose that intracranial delivery of drugs such as nimodipine, formulated in sustained-release preparations, are good candidates for improving outcome after subarachnoid hemorrhage because they can be administered to patients that are already undergoing surgery and who have a self-limited condition from which full recovery is possible.

  5. Light water reactor fuel analysis code FEMAXI-7. Model and structure

    International Nuclear Information System (INIS)

    Suzuki, Motoe; Udagawa, Yutaka; Nagase, Fumihisa; Saitou, Hiroaki

    2013-07-01

    A light water reactor fuel analysis code FEMAXI-7 has been developed for the purpose of analyzing the fuel behavior in both normal conditions and anticipated transient conditions. This code is an advanced version which has been produced by incorporating the former version FEMAXI-6 with numerous functional improvements and extensions. In FEMAXI-7, many new models have been added and parameters have been clearly arranged. Also, to facilitate effective maintenance and accessibility of the code, modularization of subroutines and functions have been attained, and quality comment descriptions of variables or physical quantities have been incorporated in the source code. With these advancements, the FEMAXI-7 code has been upgraded to a versatile analytical tool for high burnup fuel behavior analyses. This report describes in detail the design, basic theory and structure, models and numerical method of FEMAXI-7, and its improvements and extensions. (author)

  6. Network Coded Cooperative Communication in a Real-Time Wireless Hospital Sensor Network.

    Science.gov (United States)

    Prakash, R; Balaji Ganesh, A; Sivabalan, Somu

    2017-05-01

    The paper presents a network coded cooperative communication (NC-CC) enabled wireless hospital sensor network architecture for monitoring health as well as postural activities of a patient. A wearable device, referred as a smartband is interfaced with pulse rate, body temperature sensors and an accelerometer along with wireless protocol services, such as Bluetooth and Radio-Frequency transceiver and Wi-Fi. The energy efficiency of wearable device is improved by embedding a linear acceleration based transmission duty cycling algorithm (NC-DRDC). The real-time demonstration is carried-out in a hospital environment to evaluate the performance characteristics, such as power spectral density, energy consumption, signal to noise ratio, packet delivery ratio and transmission offset. The resource sharing and energy efficiency features of network coding technique are improved by proposing an algorithm referred as network coding based dynamic retransmit/rebroadcast decision control (LA-TDC). From the experimental results, it is observed that the proposed LA-TDC algorithm reduces network traffic and end-to-end delay by an average of 27.8% and 21.6%, respectively than traditional network coded wireless transmission. The wireless architecture is deployed in a hospital environment and results are then successfully validated.

  7. Effect of initial conditions and Mach number on the Richtmyer-Meshkov instability in ICF like conditions

    Science.gov (United States)

    Rao, Pooja; She, Dan; Lim, Hyunkyung; Glimm, James

    2015-11-01

    The qualitative and quantitative effect of initial conditions (linear and non-linear) and high Mach number (1.3 and 1.45) is studied on the turbulent mixing induced by the Richtmyer-Meshkov instability in idealized ICF conditions. The Richtmyer-Meshkov instability seeds Rayleigh-taylor instabilities in ICF experiments and is one of the factors that contributes to reduced performance of ICF experiments. Its also found in collapsing cores of stars and supersonic combustion. We use the Stony Brook University code, FronTier, which is verified via a code comparison study against the AMR multiphysics code FLASH, and validated against vertical shock tube experiments done by the LANL Extreme Fluids Team. These simulations are designed as a step towards simulating more realistic ICF conditions and quantifying the detrimental effects of mixing on the yield.

  8. The assessment of containment codes by experiments simulating severe accident scenarios

    International Nuclear Information System (INIS)

    Karwat, H.

    1992-01-01

    Hitherto, a generally applicable validation matrix for codes simulating the containment behaviour under severe accident conditions did not exist. Past code applications have shown that most problems may be traced back to inaccurate thermalhydraulic parameters governing gas- or aerosol-distribution events. A provisional code-validation matrix is proposed, based on a careful selection of containment experiments performed during recent years in relevant test facilities under various operating conditions. The matrix focuses on the thermalhydraulic aspects of the containment behaviour after severe accidents as a first important step. It may be supplemented in the future by additional suitable tests

  9. Regulation on the general conditions of sale and delivery of radioactive materials of the 15th December 1987

    International Nuclear Information System (INIS)

    1988-01-01

    The regulation governing the cooperation between suppliers and customers of radioactive materials was issued by the Ministry of Chemical Industry and entered into force on 1 March 1988. The following articles are covered: definition, contents and form of supply contracts, licensing and registration, quality and labelling, delivery note, transport, terms of delivery, quality control, packaging, and reuse

  10. Monte-Carlo code calculation of 3D reactor core model with usage of burnt fuel isotopic compositions, obtained by engineering codes

    Energy Technology Data Exchange (ETDEWEB)

    Aleshin, Sergey S.; Gorodkov, Sergey S.; Shcherenko, Anna I. [National Research Centre ' Kurchatov Institute' , Moscow (Russian Federation)

    2016-09-15

    A burn-up calculation of large systems by Monte-Carlo code (MCU) is complex process and it requires large computational costs. Previously prepared isotopic compositions are proposed to be used for the Monte-Carlo code calculations of different system states with burnt fuel. Isotopic compositions are calculated by an approximation method. The approximation method is based on usage of a spectral functionality and reference isotopic compositions, that are calculated by the engineering codes (TVS-M, BIPR-7A and PERMAK-A). The multiplication factors and power distributions of FAs from a 3-D reactor core are calculated in this work by the Monte-Carlo code MCU using earlier prepared isotopic compositions. The separate conditions of the burnt core are observed. The results of MCU calculations were compared with those that were obtained by engineering codes.

  11. COUPLED SIMULATION OF GAS COOLED FAST REACTOR FUEL ASSEMBLY WITH NESTLE CODE SYSTEM

    Directory of Open Access Journals (Sweden)

    Filip Osusky

    2018-05-01

    Full Text Available The paper is focused on coupled calculation of the Gas Cooled Fast Reactor. The proper modelling of coupled neutronics and thermal-hydraulics is the corner stone for future safety assessment of the control and emergency systems. Nowadays, the system and channel thermal-hydraulic codes are accepted by the national regulatory authorities in European Union for license purposes, therefore the code NESTLE was used for the simulation. The NESTLE code is a coupled multigroup neutron diffusion code with thermal-hydraulic sub-channel code. In the paper, the validation of NESTLE code 5.2.1 installation is presented. The processing of fuel assembly homogeneous parametric cross-section library for NESTLE code simulation is made by the sequence TRITON of SCALE code package system. The simulated case in the NESTLE code is one fuel assembly of GFR2400 concept with reflective boundary condition in radial direction and zero flux boundary condition in axial direction. The results of coupled calculation are presented and are consistent with the GFR2400 study of the GoFastR project.

  12. Self-nanoemulsifying drug delivery systems for oral insulin delivery

    DEFF Research Database (Denmark)

    Li, Ping; Tan, Angel; Prestidge, Clive A

    2014-01-01

    This study aims at evaluating the combination of self-nanoemulsifying drug delivery systems (SNEDDS) and enteric-coated capsules as a potential delivery strategy for oral delivery of insulin. The SNEDDS preconcentrates, loaded with insulin-phospholipid complex at different levels (0, 2.5 and 10% w...

  13. An Adaptive Coding Scheme For Effective Bandwidth And Power ...

    African Journals Online (AJOL)

    Codes for communication channels are in most cases chosen on the basis of the signal to noise ratio expected on a given transmission channel. The worst possible noise condition is normally assumed in the choice of appropriate codes such that a specified minimum error shall result during transmission on the channel.

  14. Transdermal drug delivery

    OpenAIRE

    Prausnitz, Mark R.; Langer, Robert

    2008-01-01

    Transdermal drug delivery has made an important contribution to medical practice, but has yet to fully achieve its potential as an alternative to oral delivery and hypodermic injections. First-generation transdermal delivery systems have continued their steady increase in clinical use for delivery of small, lipophilic, low-dose drugs. Second-generation delivery systems using chemical enhancers, non-cavitational ultrasound and iontophoresis have also resulted in clinical products; the ability ...

  15. Safety in nuclear power plant siting. A code of practice

    International Nuclear Information System (INIS)

    1978-01-01

    This publication is brought out within the framework of establishing Codes of Practice and Safety Guides for nuclear power plants: NUSS programme. The scope of the document encompasses site and site-plant interaction factors related to operational states and accident conditions. The purpose of the Code is to give criteria and procedures to be applied as appropriate to operational states and accident conditions, including those which could lead to emergency situations. This Code is mainly concerned with severe events of low probability which relate to the siting of nuclear power plants and have to be considered in designing a particular nuclear power plant. Annex: Examples of natural and man-made events relevant for design basis evaluation

  16. Advanced thermionic reactor systems design code

    International Nuclear Information System (INIS)

    Lewis, B.R.; Pawlowski, R.A.; Greek, K.J.; Klein, A.C.

    1991-01-01

    An overall systems design code is under development to model an advanced in-core thermionic nuclear reactor system for space applications at power levels of 10 to 50 kWe. The design code is written in an object-oriented programming environment that allows the use of a series of design modules, each of which is responsible for the determination of specific system parameters. The code modules include a neutronics and core criticality module, a core thermal hydraulics module, a thermionic fuel element performance module, a radiation shielding module, a module for waste heat transfer and rejection, and modules for power conditioning and control. The neutronics and core criticality module determines critical core size, core lifetime, and shutdown margins using the criticality calculation capability of the Monte Carlo Neutron and Photon Transport Code System (MCNP). The remaining modules utilize results of the MCNP analysis along with FORTRAN programming to predict the overall system performance

  17. Real depletion in nodal diffusion codes

    International Nuclear Information System (INIS)

    Petkov, P.T.

    2002-01-01

    The fuel depletion is described by more than one hundred fuel isotopes in the advanced lattice codes like HELIOS, but only a few fuel isotopes are accounted for even in the advanced steady-state diffusion codes. The general assumption that the number densities of the majority of the fuel isotopes depend only on the fuel burnup is seriously in error if high burnup is considered. The real depletion conditions in the reactor core differ from the asymptotic ones at the stage of lattice depletion calculations. This study reveals which fuel isotopes should be explicitly accounted for in the diffusion codes in order to predict adequately the real depletion effects in the core. A somewhat strange conclusion is that if the real number densities of the main fissionable isotopes are not explicitly accounted for in the diffusion code, then Sm-149 should not be accounted for either, because the net error in k-inf is smaller (Authors)

  18. Nonlinear to Linear Elastic Code Coupling in 2-D Axisymmetric Media.

    Energy Technology Data Exchange (ETDEWEB)

    Preston, Leiph [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-08-01

    Explosions within the earth nonlinearly deform the local media, but at typical seismological observation distances, the seismic waves can be considered linear. Although nonlinear algorithms can simulate explosions in the very near field well, these codes are computationally expensive and inaccurate at propagating these signals to great distances. A linearized wave propagation code, coupled to a nonlinear code, provides an efficient mechanism to both accurately simulate the explosion itself and to propagate these signals to distant receivers. To this end we have coupled Sandia's nonlinear simulation algorithm CTH to a linearized elastic wave propagation code for 2-D axisymmetric media (axiElasti) by passing information from the nonlinear to the linear code via time-varying boundary conditions. In this report, we first develop the 2-D axisymmetric elastic wave equations in cylindrical coordinates. Next we show how we design the time-varying boundary conditions passing information from CTH to axiElasti, and finally we demonstrate the coupling code via a simple study of the elastic radius.

  19. Thermal hydraulic-severe accident code interfaces for SCDAP/RELAP5/MOD3.2

    Energy Technology Data Exchange (ETDEWEB)

    Coryell, E.W.; Siefken, L.J.; Harvego, E.A. [Idaho National Engineering Lab., Idaho Falls, ID (United States)] [and others

    1997-07-01

    The SCDAP/RELAP5 computer code is designed to describe the overall reactor coolant system thermal-hydraulic response, core damage progression, and fission product release during severe accidents. The code is being developed at the Idaho National Engineering Laboratory under the primary sponsorship of the Office of Nuclear Regulatory Research of the U.S. Nuclear Regulatory Commission. The code is the result of merging the RELAP5, SCDAP, and COUPLE codes. The RELAP5 portion of the code calculates the overall reactor coolant system, thermal-hydraulics, and associated reactor system responses. The SCDAP portion of the code describes the response of the core and associated vessel structures. The COUPLE portion of the code describes response of lower plenum structures and debris and the failure of the lower head. The code uses a modular approach with the overall structure, input/output processing, and data structures following the pattern established for RELAP5. The code uses a building block approach to allow the code user to easily represent a wide variety of systems and conditions through a powerful input processor. The user can represent a wide variety of experiments or reactor designs by selecting fuel rods and other assembly structures from a range of representative core component models, and arrange them in a variety of patterns within the thermalhydraulic network. The COUPLE portion of the code uses two-dimensional representations of the lower plenum structures and debris beds. The flow of information between the different portions of the code occurs at each system level time step advancement. The RELAP5 portion of the code describes the fluid transport around the system. These fluid conditions are used as thermal and mass transport boundary conditions for the SCDAP and COUPLE structures and debris beds.

  20. Thermal hydraulic-severe accident code interfaces for SCDAP/RELAP5/MOD3.2

    International Nuclear Information System (INIS)

    Coryell, E.W.; Siefken, L.J.; Harvego, E.A.

    1997-01-01

    The SCDAP/RELAP5 computer code is designed to describe the overall reactor coolant system thermal-hydraulic response, core damage progression, and fission product release during severe accidents. The code is being developed at the Idaho National Engineering Laboratory under the primary sponsorship of the Office of Nuclear Regulatory Research of the U.S. Nuclear Regulatory Commission. The code is the result of merging the RELAP5, SCDAP, and COUPLE codes. The RELAP5 portion of the code calculates the overall reactor coolant system, thermal-hydraulics, and associated reactor system responses. The SCDAP portion of the code describes the response of the core and associated vessel structures. The COUPLE portion of the code describes response of lower plenum structures and debris and the failure of the lower head. The code uses a modular approach with the overall structure, input/output processing, and data structures following the pattern established for RELAP5. The code uses a building block approach to allow the code user to easily represent a wide variety of systems and conditions through a powerful input processor. The user can represent a wide variety of experiments or reactor designs by selecting fuel rods and other assembly structures from a range of representative core component models, and arrange them in a variety of patterns within the thermalhydraulic network. The COUPLE portion of the code uses two-dimensional representations of the lower plenum structures and debris beds. The flow of information between the different portions of the code occurs at each system level time step advancement. The RELAP5 portion of the code describes the fluid transport around the system. These fluid conditions are used as thermal and mass transport boundary conditions for the SCDAP and COUPLE structures and debris beds

  1. Safe delivery practices: experience from cross-sectional data of Bangladeshi women.

    Science.gov (United States)

    Kabir, M A; Goh, Kim-Leng; Khan, M M H; Al-Amin, Abul Quasem; Azam, Mohammad Nurul

    2015-03-01

    This study examines the safe delivery practices of Bangladeshi women using data on 4905 ever-married women aged 15 to 49 years from the 2007 Bangladesh Demographic and Health Survey. Variables that included age, region of origin, education level of respondent and spouse, residence, working status, religion, involvement in NGOs, mass media exposure, and wealth index were analyzed to find correlates of safe delivery practices. More than 80% of the deliveries took place at home, and only 18% were under safe and hygienic conditions. The likelihood of safe deliveries was significantly lower among younger and older mothers than middle-aged mothers and higher among educated mothers and those living in urban areas. Economically better-off mothers and those with greater exposure to mass media had a significantly higher incidence of safe delivery practices. A significant association with religion and safe delivery practices was revealed. Demographic, socioeconomic, cultural, and programmatic factors that are strongly associated with safe delivery practices should be considered in the formulation of reproductive health policy. © 2012 APJPH.

  2. The Effect of Different Delivery Conditions on the Accelerated Degradation of Structural Steel in the Coal Mine Environment / Wpływ Różnego Stanu Dostawy Na Przyspieszoną Degradację Stali Konstrukcyjnej W Środowisku Kopalnianym

    Science.gov (United States)

    Pawłowski, Bogdan; Bała, Piotr

    2012-12-01

    The main objective of this work was to determine the effect of different delivery conditions on the accelerated degradation of structural steels used for lifting beams (rails) of the monorail transport systems. Some of these rails, made of the same steel grade as others, undergoes accelerated corrosion in the coal mine environment. Corrosion degradation occurs much faster (more than two times faster), comparing to the same steel grade rails operated under the same conditions but with different microstructures. However, all the provided rails meet the requirements of appropriate standards for steel on the lifting beams of the monorail transport systems. The investigations were carried out on rails made of the same steel grade but with different microstructures and showed that the main factor influencing the accelerated corrosion degradation of tested steels is the delivery condition, so-called "as rolled" condition. The greatest resistance to the accelerated corrosion showed rails in the normalized or normalizing rolling condition.

  3. Large-Scale Analysis of Remote Code Injection Attacks in Android Apps

    OpenAIRE

    Choi, Hyunwoo; Kim, Yongdae

    2018-01-01

    It is pretty well known that insecure code updating procedures for Android allow remote code injection attack. However, other than codes, there are many resources in Android that have to be updated, such as temporary files, images, databases, and configurations (XML and JSON). Security of update procedures for these resources is largely unknown. This paper investigates general conditions for remote code injection attacks on these resources. Using this, we design and implement a static detecti...

  4. Pretest aerosol code comparisons for LWR aerosol containment tests LA1 and LA2

    International Nuclear Information System (INIS)

    Wright, A.L.; Wilson, J.H.; Arwood, P.C.

    1986-01-01

    The Light-Water-Reactor (LWR) Aerosol Containment Experiments (LACE) are being performed in Richland, Washington, at the Hanford Engineering Development Laboratory (HEDL) under the leadership of an international project board and the Electric Power Research Institute. These tests have two objectives: (1) to investigate, at large scale, the inherent aerosol retention behavior in LWR containments under simulated severe accident conditions, and (2) to provide an experimental data base for validating aerosol behavior and thermal-hydraulic computer codes. Aerosol computer-code comparison activities are being coordinated at the Oak Ridge National Laboratory. For each of the six LACE tests, ''pretest'' calculations (for code-to-code comparisons) and ''posttest'' calculations (for code-to-test data comparisons) are being performed. The overall goals of the comparison effort are (1) to provide code users with experience in applying their codes to LWR accident-sequence conditions and (2) to evaluate and improve the code models

  5. Advances in the Applications of Polyhydroxyalkanoate Nanoparticles for Novel Drug Delivery System

    Directory of Open Access Journals (Sweden)

    Anupama Shrivastav

    2013-01-01

    Full Text Available Drug delivery technology is emerging as an interdisciplinary science aimed at improving human health. The controlled delivery of pharmacologically active agents to the specific site of action at the therapeutically optimal rate and dose regimen has been a major goal in designing drug delivery systems. Over the past few decades, there has been considerable interest in developing biodegradable drug carriers as effective drug delivery systems. Polymeric materials from natural sources play an important role in controlled release of drug at a particular site. Polyhydroxyalkanoates, due to their origin from natural sources, are given attention as candidates for drug delivery materials. Biodegradable and biocompatible polyhydroxyalkanoates are linear polyesters produced by microorganisms under unbalanced growth conditions, which have emerged as potential polymers for use as biomedical materials for drug delivery due to their unique physiochemical and mechanical properties. This review summarizes many of the key findings in the applications of polyhydroxyalkanoates and polyhydroxyalkanoate nanoparticles for drug delivery system.

  6. Complications of cesarean deliveries among HIV-infected women in the United States

    Science.gov (United States)

    Kourtis, Athena P.; Ellington, Sascha; Pazol, Karen; Flowers, Lisa; Haddad, Lisa; Jamieson, Denise J.

    2015-01-01

    Objective To compare rates of complications associated with cesarean delivery in HIV-infected and HIV-uninfected women in the United States and to investigate trends in such complications across four study cycles spanning the implementation of HAART in the United States (1995–1996, 2000–2001, 2005–2006, 2010–2011). Design The Nationwide Inpatient Sample from the Healthcare Cost and Utilization Project is the largest all-payer hospital inpatient care database in the United States; when weighted to account for the complex sampling design, nationally representative estimates are derived. After restricting the study sample to women aged 15–49 years, our study sample consisted of approximately 1 090 000 cesarean delivery hospitalizations annually. Methods Complications associated with cesarean deliveries were categorized as infection, hemorrhage, or surgical trauma, based on groups of specific International Classification of Diseases 9th revision codes. Length of hospitalization, hospital charges, and in-hospital deaths were also examined. Results The rate of complications significantly decreased during the study periods for HIV-infected and HIV-uninfected women. However, rates of infectious complications and surgical trauma associated with cesarean deliveries remained higher among HIV-infected, compared with HIV-uninfected women in 2010–2011, as did prolonged hospital stay and in-hospital deaths. Length of hospitalization decreased over time for cesarean deliveries of HIV-infected women to a greater extent compared with HIV-uninfected women. Conclusion In the United States, rates of cesarean delivery complications decreased from 1995 to 2011. However, rates of infection, surgical trauma, hospital deaths, and prolonged hospitalization are still higher among HIV-infected women. Clinicians should remain alert to this persistently increased risk of cesarean delivery complications among HIV-infected women. PMID:25574961

  7. Use of computer codes to improve nuclear power plant operation

    International Nuclear Information System (INIS)

    Misak, J.; Polak, V.; Filo, J.; Gatas, J.

    1985-01-01

    For safety and economic reasons, the scope for carrying out experiments on operational nuclear power plants (NPPs) is very limited and any changes in technical equipment and operating parameters or conditions have to be supported by theoretical calculations. In the Nuclear Power Plant Scientific Research Institute (NIIAEhS), computer codes are systematically used to analyse actual operating events, assess safety aspects of changes in equipment and operating conditions, optimize the conditions, preparation and analysis of NPP startup trials and review and amend operating instructions. In addition, calculation codes are gradually being introduced into power plant computer systems to perform real time processing of the parameters being measured. The paper describes a number of specific examples of the use of calculation codes for the thermohydraulic analysis of operating and accident conditions aimed at improving the operation of WWER-440 units at the Jaslovske Bohunice V-1 and V-2 nuclear power plants. These examples confirm that computer calculations are an effective way of solving operating problems and of further increasing the level of safety and economic efficiency of NPP operation. (author)

  8. Void fraction prediction of NUPEC PSBT tests by CATHARE code

    International Nuclear Information System (INIS)

    Del Nevo, A.; Michelotti, L.; Moretti, F.; Rozzia, D.; D'Auria, F.

    2011-01-01

    The current generation of thermal-hydraulic system codes benefits of about sixty years of experiments and forty years of development and are considered mature tools to provide best estimate description of phenomena and detailed reactor system representations. However, there are continuous needs for checking the code capabilities in representing nuclear system, for drawing attention to their weak points, for identifying models which need to be refined for best-estimate calculations. Prediction of void fraction and Departure from Nucleate Boiling (DNB) in system thermal-hydraulics is currently based on empirical approaches. The database carried out by Nuclear Power Engineering Corporation (NUPEC), Japan addresses these issues. It is suitable for supporting the development of new computational tools based on more mechanistic approaches (i.e. three-field codes, two-phase CFD, etc.) as well as for validating current generation of thermal-hydraulic system codes. Selected experiments belonging to this database are used for the OECD/NRC PSBT benchmark. The paper reviews the activity carried out by CATHARE2 code on the basis of the subchannel (four test sections) and presents rod bundle (different axial power profile and test sections) experiments available in the database in steady state and transient conditions. The results demonstrate the accuracy of the code in predicting the void fraction in different thermal-hydraulic conditions. The tests are performed varying the pressure, coolant temperature, mass flow and power. Sensitivity analyses are carried out addressing nodalization effect and the influence of the initial and boundary conditions of the tests. (author)

  9. Toward Understanding Mechanisms Controlling Urea Delivery in a Coastal Plain Watershed

    Science.gov (United States)

    Tzilkowski, S. S.; Buda, A. R.; Boyer, E. W.; Bryant, R. B.; May, E. B.

    2012-12-01

    Improved understanding of nutrient mobilization and delivery to surface waters is critical to protecting water quality in agricultural watersheds. Urea, a form of organic nitrogen, is a common nutrient found in fertilizers, manures, and human waste, and is gaining recognition as an important driver of coastal eutrophication, particularly through the development of harmful algal blooms. While several studies have documented elevated urea concentrations in tributaries draining to the Chesapeake Bay, little is known about the potential sources and flow pathways responsible for urea delivery from the landscape to surface waters, as well as how these sources and pathways might vary with changing seasons, antecedent conditions, and storm types. In this study, we investigated hydrologic controls on urea delivery in the Manokin River watershed through the analysis of urea concentration dynamics and hysteresis patterns during seven storm events that occurred in 2010 and 2011. The Manokin River is a Coastal Plain watershed (11.1 km2) on the Delmarva Peninsula that drains directly to the Chesapeake Bay and is characterized by extensive rural development coupled with intensive agriculture, particularly poultry production. Sampling was conducted through monthly grab sampling at baseflow conditions and by time-weighted, automated (Sigma) samplers during stormflow events. Monitored storms were chosen to represent a spectrum of antecedent conditions based on precipitation and groundwater levels in the area. Flushing from the landscape during events was found to be the predominant urea delivery mechanism, as urea concentrations increased 3-9 times above baseflow concentrations during storms. The timing and number of flushes, as well as the degree of increased concentrations were dependent on antecedent conditions and the characteristics of the storm event. For instance, during an intense (13.7 mm hr-1), short-duration (4 hrs) storm in August of 2010 when antecedent conditions were

  10. Rate-adaptive BCH codes for distributed source coding

    DEFF Research Database (Denmark)

    Salmistraro, Matteo; Larsen, Knud J.; Forchhammer, Søren

    2013-01-01

    This paper considers Bose-Chaudhuri-Hocquenghem (BCH) codes for distributed source coding. A feedback channel is employed to adapt the rate of the code during the decoding process. The focus is on codes with short block lengths for independently coding a binary source X and decoding it given its...... strategies for improving the reliability of the decoded result are analyzed, and methods for estimating the performance are proposed. In the analysis, noiseless feedback and noiseless communication are assumed. Simulation results show that rate-adaptive BCH codes achieve better performance than low...... correlated side information Y. The proposed codes have been analyzed in a high-correlation scenario, where the marginal probability of each symbol, Xi in X, given Y is highly skewed (unbalanced). Rate-adaptive BCH codes are presented and applied to distributed source coding. Adaptive and fixed checking...

  11. Pancreatic Cancer Gene Therapy: From Molecular Targets to Delivery Systems

    Energy Technology Data Exchange (ETDEWEB)

    Fillat, Cristina, E-mail: cristina.fillat@crg.es; Jose, Anabel; Ros, Xavier Bofill-De; Mato-Berciano, Ana; Maliandi, Maria Victoria; Sobrevals, Luciano [Programa Gens i Malaltia, Centre de Regulació Genòmica-CRG, UPF, Parc de Recerca Biomedica de Barcelona-PRBB and Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Barcelona (Spain)

    2011-01-18

    The continuous identification of molecular changes deregulating critical pathways in pancreatic tumor cells provides us with a large number of novel candidates to engineer gene-targeted approaches for pancreatic cancer treatment. Targets—both protein coding and non-coding—are being exploited in gene therapy to influence the deregulated pathways to facilitate cytotoxicity, enhance the immune response or sensitize to current treatments. Delivery vehicles based on viral or non-viral systems as well as cellular vectors with tumor homing characteristics are a critical part of the design of gene therapy strategies. The different behavior of tumoral versus non-tumoral cells inspires vector engineering with the generation of tumor selective products that can prevent potential toxic-associated effects. In the current review, a detailed analysis of the different targets, the delivery vectors, the preclinical approaches and a descriptive update on the conducted clinical trials are presented. Moreover, future possibilities in pancreatic cancer treatment by gene therapy strategies are discussed.

  12. Code manual for CONTAIN 2.0: A computer code for nuclear reactor containment analysis

    International Nuclear Information System (INIS)

    Murata, K.K.; Williams, D.C.; Griffith, R.O.; Gido, R.G.; Tadios, E.L.; Davis, F.J.; Martinez, G.M.; Washington, K.E.; Tills, J.

    1997-12-01

    The CONTAIN 2.0 computer code is an integrated analysis tool used for predicting the physical conditions, chemical compositions, and distributions of radiological materials inside a containment building following the release of material from the primary system in a light-water reactor accident. It can also predict the source term to the environment. CONTAIN 2.0 is intended to replace the earlier CONTAIN 1.12, which was released in 1991. The purpose of this Code Manual is to provide full documentation of the features and models in CONTAIN 2.0. Besides complete descriptions of the models, this Code Manual provides a complete description of the input and output from the code. CONTAIN 2.0 is a highly flexible and modular code that can run problems that are either quite simple or highly complex. An important aspect of CONTAIN is that the interactions among thermal-hydraulic phenomena, aerosol behavior, and fission product behavior are taken into account. The code includes atmospheric models for steam/air thermodynamics, intercell flows, condensation/evaporation on structures and aerosols, aerosol behavior, and gas combustion. It also includes models for reactor cavity phenomena such as core-concrete interactions and coolant pool boiling. Heat conduction in structures, fission product decay and transport, radioactive decay heating, and the thermal-hydraulic and fission product decontamination effects of engineered safety features are also modeled. To the extent possible, the best available models for severe accident phenomena have been incorporated into CONTAIN, but it is intrinsic to the nature of accident analysis that significant uncertainty exists regarding numerous phenomena. In those cases, sensitivity studies can be performed with CONTAIN by means of user-specified input parameters. Thus, the code can be viewed as a tool designed to assist the knowledge reactor safety analyst in evaluating the consequences of specific modeling assumptions

  13. Code manual for CONTAIN 2.0: A computer code for nuclear reactor containment analysis

    Energy Technology Data Exchange (ETDEWEB)

    Murata, K.K.; Williams, D.C.; Griffith, R.O.; Gido, R.G.; Tadios, E.L.; Davis, F.J.; Martinez, G.M.; Washington, K.E. [Sandia National Labs., Albuquerque, NM (United States); Tills, J. [J. Tills and Associates, Inc., Sandia Park, NM (United States)

    1997-12-01

    The CONTAIN 2.0 computer code is an integrated analysis tool used for predicting the physical conditions, chemical compositions, and distributions of radiological materials inside a containment building following the release of material from the primary system in a light-water reactor accident. It can also predict the source term to the environment. CONTAIN 2.0 is intended to replace the earlier CONTAIN 1.12, which was released in 1991. The purpose of this Code Manual is to provide full documentation of the features and models in CONTAIN 2.0. Besides complete descriptions of the models, this Code Manual provides a complete description of the input and output from the code. CONTAIN 2.0 is a highly flexible and modular code that can run problems that are either quite simple or highly complex. An important aspect of CONTAIN is that the interactions among thermal-hydraulic phenomena, aerosol behavior, and fission product behavior are taken into account. The code includes atmospheric models for steam/air thermodynamics, intercell flows, condensation/evaporation on structures and aerosols, aerosol behavior, and gas combustion. It also includes models for reactor cavity phenomena such as core-concrete interactions and coolant pool boiling. Heat conduction in structures, fission product decay and transport, radioactive decay heating, and the thermal-hydraulic and fission product decontamination effects of engineered safety features are also modeled. To the extent possible, the best available models for severe accident phenomena have been incorporated into CONTAIN, but it is intrinsic to the nature of accident analysis that significant uncertainty exists regarding numerous phenomena. In those cases, sensitivity studies can be performed with CONTAIN by means of user-specified input parameters. Thus, the code can be viewed as a tool designed to assist the knowledge reactor safety analyst in evaluating the consequences of specific modeling assumptions.

  14. Development of Monte Carlo-based pebble bed reactor fuel management code

    International Nuclear Information System (INIS)

    Setiadipura, Topan; Obara, Toru

    2014-01-01

    Highlights: • A new Monte Carlo-based fuel management code for OTTO cycle pebble bed reactor was developed. • The double-heterogeneity was modeled using statistical method in MVP-BURN code. • The code can perform analysis of equilibrium and non-equilibrium phase. • Code-to-code comparisons for Once-Through-Then-Out case were investigated. • Ability of the code to accommodate the void cavity was confirmed. - Abstract: A fuel management code for pebble bed reactors (PBRs) based on the Monte Carlo method has been developed in this study. The code, named Monte Carlo burnup analysis code for PBR (MCPBR), enables a simulation of the Once-Through-Then-Out (OTTO) cycle of a PBR from the running-in phase to the equilibrium condition. In MCPBR, a burnup calculation based on a continuous-energy Monte Carlo code, MVP-BURN, is coupled with an additional utility code to be able to simulate the OTTO cycle of PBR. MCPBR has several advantages in modeling PBRs, namely its Monte Carlo neutron transport modeling, its capability of explicitly modeling the double heterogeneity of the PBR core, and its ability to model different axial fuel speeds in the PBR core. Analysis at the equilibrium condition of the simplified PBR was used as the validation test of MCPBR. The calculation results of the code were compared with the results of diffusion-based fuel management PBR codes, namely the VSOP and PEBBED codes. Using JENDL-4.0 nuclide library, MCPBR gave a 4.15% and 3.32% lower k eff value compared to VSOP and PEBBED, respectively. While using JENDL-3.3, MCPBR gave a 2.22% and 3.11% higher k eff value compared to VSOP and PEBBED, respectively. The ability of MCPBR to analyze neutron transport in the top void of the PBR core and its effects was also confirmed

  15. Two-phase flow characteristics analysis code: MINCS

    International Nuclear Information System (INIS)

    Watanabe, Tadashi; Hirano, Masashi; Akimoto, Masayuki; Tanabe, Fumiya; Kohsaka, Atsuo.

    1992-03-01

    Two-phase flow characteristics analysis code: MINCS (Modularized and INtegrated Code System) has been developed to provide a computational tool for analyzing two-phase flow phenomena in one-dimensional ducts. In MINCS, nine types of two-phase flow models-from a basic two-fluid nonequilibrium (2V2T) model to a simple homogeneous equilibrium (1V1T) model-can be used under the same numerical solution method. The numerical technique is based on the implicit finite difference method to enhance the numerical stability. The code structure is highly modularized, so that new constitutive relations and correlations can be easily implemented into the code and hence evaluated. A flow pattern can be fixed regardless of flow conditions, and state equations or steam tables can be selected. It is, therefore, easy to calculate physical or numerical benchmark problems. (author)

  16. Diagonal Eigenvalue Unity (DEU) code for spectral amplitude coding-optical code division multiple access

    Science.gov (United States)

    Ahmed, Hassan Yousif; Nisar, K. S.

    2013-08-01

    Code with ideal in-phase cross correlation (CC) and practical code length to support high number of users are required in spectral amplitude coding-optical code division multiple access (SAC-OCDMA) systems. SAC systems are getting more attractive in the field of OCDMA because of its ability to eliminate the influence of multiple access interference (MAI) and also suppress the effect of phase induced intensity noise (PIIN). In this paper, we have proposed new Diagonal Eigenvalue Unity (DEU) code families with ideal in-phase CC based on Jordan block matrix with simple algebraic ways. Four sets of DEU code families based on the code weight W and number of users N for the combination (even, even), (even, odd), (odd, odd) and (odd, even) are constructed. This combination gives DEU code more flexibility in selection of code weight and number of users. These features made this code a compelling candidate for future optical communication systems. Numerical results show that the proposed DEU system outperforms reported codes. In addition, simulation results taken from a commercial optical systems simulator, Virtual Photonic Instrument (VPI™) shown that, using point to multipoint transmission in passive optical network (PON), DEU has better performance and could support long span with high data rate.

  17. List Decoding of Matrix-Product Codes from nested codes: an application to Quasi-Cyclic codes

    DEFF Research Database (Denmark)

    Hernando, Fernando; Høholdt, Tom; Ruano, Diego

    2012-01-01

    A list decoding algorithm for matrix-product codes is provided when $C_1,..., C_s$ are nested linear codes and $A$ is a non-singular by columns matrix. We estimate the probability of getting more than one codeword as output when the constituent codes are Reed-Solomon codes. We extend this list...... decoding algorithm for matrix-product codes with polynomial units, which are quasi-cyclic codes. Furthermore, it allows us to consider unique decoding for matrix-product codes with polynomial units....

  18. Recent progress on weight distributions of cyclic codes over finite fields

    Directory of Open Access Journals (Sweden)

    Hai Q. Dinh

    2015-01-01

    Full Text Available Cyclic codes are an interesting type of linear codes and have wide applications in communication and storage systems due to their efficient encoding and decoding algorithms. In coding theory it is often desirable to know the weight distribution of a cyclic code to estimate the error correcting capability and error probability. In this paper, we present the recent progress on the weight distributions of cyclic codes over finite fields, which had been determined by exponential sums. The cyclic codes with few weights which are very useful are discussed and their existence conditions are listed. Furthermore, we discuss the more general case of constacyclic codes and give some equivalences to characterize their weight distributions.

  19. SSI and the Environmental Code

    International Nuclear Information System (INIS)

    Loefgren, T.

    1997-12-01

    Radiation is, to some extent, included in the environmental code being prepared by the government. As a consequence both the Radiation Protection Institute and the proposed Environmental Court may set legal conditions concerning radiation protection for the proponent. Legal and other matters related to this issue are discussed in the report

  20. Severe Maternal Morbidity and Hospital Cost among Hospitalized Deliveries in the United States.

    Science.gov (United States)

    Chen, Han-Yang; Chauhan, Suneet P; Blackwell, Sean C

    2018-05-03

     The objective of this study was to estimate the contemporary national rate of severe maternal morbidity (SMM) and its associated hospital cost during delivery hospitalization.  We conducted a retrospective study identifying all delivery hospitalizations in the United States between 2011 and 2012. We used data from the National (Nationwide) Inpatient sample of the Healthcare Cost and Utilization Project. The delivery hospitalizations with SMM were identified by having at least one of the 25 previously established list of diagnosis and procedure codes. Aggregate and mean hospital costs were estimated. A generalized linear regression model was used to examine the association between SMM and hospital costs.  Of 7,438,946 delivery hospitalizations identified, the rate of SMM was 154 per 10,000 delivery hospitalizations. Without any SMM, the mean hospital cost was $4,300 and with any SMM, the mean hospital cost was $11,000. After adjustment, comparing to those without any SMM, the mean cost of delivery hospitalizations with any SMM was 2.1 (95% confidence interval: 2.1-2.2) times higher, and this ratio increases from 1.7-fold in those with only one SMM to 10.3-fold in those with five or more concurrent SMM.  The hospital cost with any SMM was 2.1 times higher than those without any SMM. Our findings highlight the need to identify interventions and guide research efforts to mitigate the rate of SMM and its economic burden. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

  1. Developing HYDMN code to include the transient of MNSR

    International Nuclear Information System (INIS)

    Al-Barhoum, M.

    2000-11-01

    A description of the programs added to HYDMN code (a code for thermal-hydraulic steady state of MNSR) to include the transient of the same MNSR is presented. The code asks the initial conditions for the power (in k W) and the cold initial core inlet temperature (in degrees centigrade). A time-dependent study of the coolant inlet and outlet temperature, its speed, pool and tank temperatures is done for MNSR in general and for the Syrian MNSR in particular. The study solves the differential equations taken from reference (1) by using some numerical methods found in reference (3). The code becomes this way independent of any external information source. (Author)

  2. Neutron spallation source and the Dubna cascade code

    CERN Document Server

    Kumar, V; Goel, U; Barashenkov, V S

    2003-01-01

    Neutron multiplicity per incident proton, n/p, in collision of high energy proton beam with voluminous Pb and W targets has been estimated from the Dubna cascade code and compared with the available experimental data for the purpose of benchmarking of the code. Contributions of various atomic and nuclear processes for heat production and isotopic yield of secondary nuclei are also estimated to assess the heat and radioactivity conditions of the targets. Results obtained from the code show excellent agreement with the experimental data at beam energy, E < 1.2 GeV and differ maximum up to 25% at higher energy. (author)

  3. Combinatorial neural codes from a mathematical coding theory perspective.

    Science.gov (United States)

    Curto, Carina; Itskov, Vladimir; Morrison, Katherine; Roth, Zachary; Walker, Judy L

    2013-07-01

    Shannon's seminal 1948 work gave rise to two distinct areas of research: information theory and mathematical coding theory. While information theory has had a strong influence on theoretical neuroscience, ideas from mathematical coding theory have received considerably less attention. Here we take a new look at combinatorial neural codes from a mathematical coding theory perspective, examining the error correction capabilities of familiar receptive field codes (RF codes). We find, perhaps surprisingly, that the high levels of redundancy present in these codes do not support accurate error correction, although the error-correcting performance of receptive field codes catches up to that of random comparison codes when a small tolerance to error is introduced. However, receptive field codes are good at reflecting distances between represented stimuli, while the random comparison codes are not. We suggest that a compromise in error-correcting capability may be a necessary price to pay for a neural code whose structure serves not only error correction, but must also reflect relationships between stimuli.

  4. Codes of practice and protocols for the dosimetry in reference conditions of proton and ion beams

    International Nuclear Information System (INIS)

    Vatnitsky, S.; Andreo, P.

    2002-01-01

    The advantages of radiotherapy protons and heavier charged-particle beams, the technological feasibility, and the clinical results obtained so far have led to the establishment of about 20 treatment facilities worldwide and plans to open another 20 proton and light-ion therapy centres in the next five years. In order to meet the expanding capabilities of treatment techniques, considerable effort has been devoted during the last fifteen years to the development of the dosimetry and calibration of such beams. This paper reviews these developments and summarizes the present status of Codes of Practice and protocols for the dosimetry in reference conditions of proton and ion beams. The first dosimetry protocol for heavy-particle radiotherapy beams, AAPM TG 20, was based on the use of Faraday cups and calorimeters, whereas ionization chamber dosimetry received little attention. Following the trends in 'nuclear particle' radiotherapy, TG 20 included recommendations for specifying 'dose to tissue'. The lack of availability of a harmonized set of data for the different particles made this protocol to include data for stopping-powers and for the mean energy required to produce and ion pair in air, W air , from multiple authors, without enough attention being paid to their consistency. The increased focus into proton beams was materialized in the publication of the ECHED Code of Practice, dedicated exclusively to protons, where ionization dosimetry received more attention than in TG 20. It was not until the publication of the Supplement to the ECHED recommendations that ionization chambers having a 60 CO calibration factor were recommended as a reference detector for proton dosimetry, and data supplied for chambers with different wall materials. The emphasis on ionization chamber-based proton dosimetry was complemented with a recommendation for using water as dosimetry phantom material and the necessary data on tissue and water to air stopping-power ratios and W air . One of

  5. LDGM Codes for Channel Coding and Joint Source-Channel Coding of Correlated Sources

    Directory of Open Access Journals (Sweden)

    Javier Garcia-Frias

    2005-05-01

    Full Text Available We propose a coding scheme based on the use of systematic linear codes with low-density generator matrix (LDGM codes for channel coding and joint source-channel coding of multiterminal correlated binary sources. In both cases, the structures of the LDGM encoder and decoder are shown, and a concatenated scheme aimed at reducing the error floor is proposed. Several decoding possibilities are investigated, compared, and evaluated. For different types of noisy channels and correlation models, the resulting performance is very close to the theoretical limits.

  6. The Initial Atmospheric Transport (IAT) Code: Description and Validation

    Energy Technology Data Exchange (ETDEWEB)

    Morrow, Charles W. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Bartel, Timothy James [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-10-01

    The Initial Atmospheric Transport (IAT) computer code was developed at Sandia National Laboratories as part of their nuclear launch accident consequences analysis suite of computer codes. The purpose of IAT is to predict the initial puff/plume rise resulting from either a solid rocket propellant or liquid rocket fuel fire. The code generates initial conditions for subsequent atmospheric transport calculations. The Initial Atmospheric Transfer (IAT) code has been compared to two data sets which are appropriate to the design space of space launch accident analyses. The primary model uncertainties are the entrainment coefficients for the extended Taylor model. The Titan 34D accident (1986) was used to calibrate these entrainment settings for a prototypic liquid propellant accident while the recent Johns Hopkins University Applied Physics Laboratory (JHU/APL, or simply APL) large propellant block tests (2012) were used to calibrate the entrainment settings for prototypic solid propellant accidents. North American Meteorology (NAM )formatted weather data profiles are used by IAT to determine the local buoyancy force balance. The IAT comparisons for the APL solid propellant tests illustrate the sensitivity of the plume elevation to the weather profiles; that is, the weather profile is a dominant factor in determining the plume elevation. The IAT code performed remarkably well and is considered validated for neutral weather conditions.

  7. Complexity control algorithm based on adaptive mode selection for interframe coding in high efficiency video coding

    Science.gov (United States)

    Chen, Gang; Yang, Bing; Zhang, Xiaoyun; Gao, Zhiyong

    2017-07-01

    The latest high efficiency video coding (HEVC) standard significantly increases the encoding complexity for improving its coding efficiency. Due to the limited computational capability of handheld devices, complexity constrained video coding has drawn great attention in recent years. A complexity control algorithm based on adaptive mode selection is proposed for interframe coding in HEVC. Considering the direct proportionality between encoding time and computational complexity, the computational complexity is measured in terms of encoding time. First, complexity is mapped to a target in terms of prediction modes. Then, an adaptive mode selection algorithm is proposed for the mode decision process. Specifically, the optimal mode combination scheme that is chosen through offline statistics is developed at low complexity. If the complexity budget has not been used up, an adaptive mode sorting method is employed to further improve coding efficiency. The experimental results show that the proposed algorithm achieves a very large complexity control range (as low as 10%) for the HEVC encoder while maintaining good rate-distortion performance. For the lowdelayP condition, compared with the direct resource allocation method and the state-of-the-art method, an average gain of 0.63 and 0.17 dB in BDPSNR is observed for 18 sequences when the target complexity is around 40%.

  8. Interface requirements to couple thermal-hydraulic codes to severe accident codes: ATHLET-CD

    Energy Technology Data Exchange (ETDEWEB)

    Trambauer, K. [GRS, Garching (Germany)

    1997-07-01

    The system code ATHLET-CD is being developed by GRS in cooperation with IKE and IPSN. Its field of application comprises the whole spectrum of leaks and large breaks, as well as operational and abnormal transients for LWRs and VVERs. At present the analyses cover the in-vessel thermal-hydraulics, the early phases of core degradation, as well as fission products and aerosol release from the core and their transport in the Reactor Coolant System. The aim of the code development is to extend the simulation of core degradation up to failure of the reactor pressure vessel and to cover all physically reasonable accident sequences for western and eastern LWRs including RMBKs. The ATHLET-CD structure is highly modular in order to include a manifold spectrum of models and to offer an optimum basis for further development. The code consists of four general modules to describe the reactor coolant system thermal-hydraulics, the core degradation, the fission product core release, and fission product and aerosol transport. Each general module consists of some basic modules which correspond to the process to be simulated or to its specific purpose. Besides the code structure based on the physical modelling, the code follows four strictly separated steps during the course of a calculation: (1) input of structure, geometrical data, initial and boundary condition, (2) initialization of derived quantities, (3) steady state calculation or input of restart data, and (4) transient calculation. In this paper, the transient solution method is briefly presented and the coupling methods are discussed. Three aspects have to be considered for the coupling of different modules in one code system. First is the conservation of masses and energy in the different subsystems as there are fluid, structures, and fission products and aerosols. Second is the convergence of the numerical solution and stability of the calculation. The third aspect is related to the code performance, and running time.

  9. Exploration of ICD-9-CM Coding of Chronic Disease within the Elixhauser Comorbidity Measure in Patients with Chronic Heart Failure

    Science.gov (United States)

    Garvin, Jennifer Hornung; Redd, Andrew; Bolton, Dan; Graham, Pauline; Roche, Dominic; Groeneveld, Peter; Leecaster, Molly; Shen, Shuying; Weiner, Mark G.

    2013-01-01

    Introduction International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes capture comorbidities that can be used to risk adjust nonrandom patient groups. We explored the accuracy of capturing comorbidities associated with one risk adjustment method, the Elixhauser Comorbidity Measure (ECM), in patients with chronic heart failure (CHF) at one Veterans Affairs (VA) medical center. We explored potential reasons for the differences found between the original codes assigned and conditions found through retrospective review. Methods This descriptive, retrospective study used a cohort of patients discharged with a principal diagnosis coded as CHF from one VA medical center in 2003. One admission per patient was used in the study; with multiple admissions, only the first admission was analyzed. We compared the assignment of original codes assigned to conditions found in a retrospective, manual review of the medical record conducted by an investigator with coding expertise as well as by physicians. Members of the team experienced with assigning ICD-9-CM codes and VA coding processes developed themes related to systemic reasons why chronic conditions were not coded in VA records using applied thematic techniques. Results In the 181-patient cohort, 388 comorbid conditions were identified; 305 of these were chronic conditions, originally coded at the time of discharge with an average of 1.7 comorbidities related to the ECM per patient. The review by an investigator with coding expertise revealed a total of 937 comorbidities resulting in 618 chronic comorbid conditions with an average of 3.4 per patient; physician review found 872 total comorbidities with 562 chronic conditions (average 3.1 per patient). The agreement between the original and the retrospective coding review was 88 percent. The kappa statistic for the original and the retrospective coding review was 0.375 with a 95 percent confidence interval (CI) of 0.352 to 0.398. The kappa

  10. Linking Terrigenous Sediment Delivery to Declines in Coral ...

    Science.gov (United States)

    Worldwide coral reef conditions continue to decline despite the valuable socioeconomic benefits of these ecosystems. There is growing recognition that quantifying reefs in terms reflecting what stakeholders value is vital for comparing inherent tradeoffs among coastal management decisions. Terrestrial sediment runoff ranks high as a stressor to coral reefs and is a key concern in Puerto Rico where reefs are among the most threatened in the Caribbean. This research aimed to identify the degree to which sediment runoff impacts production of coral reef ecosystem services and the potential for watershed management actions to improve these services. Ecosystem service production functions were applied to map and translate metrics of ecological reef condition into ecosystem service production under a gradient of increasing sediment delivery. We found that higher sediment delivery decreased provisioning of most ecosystem services, including ecosystem integrity, bioprospecting discovery, and reef-based recreational opportunities and fisheries production. However, shoreline protection and services with a strong contribution from non-reef habitats (e.g., mangroves, seagrasses) were higher in locations with high sediment delivery, although there was a strong inshore effect suggesting the influence of distance to shore, depth, and inshore habitats. Differences among services may indicate potential tradeoffs and the need to consider habitat connectivity, nursery habitat, acce

  11. Comparative simulation of Stirling and Sibling cycle cryocoolers with two codes

    International Nuclear Information System (INIS)

    Mitchell, M.P.; Wilson, K.J.; Bauwens, L.

    1989-01-01

    The authors present a comparative analysis of Stirling and Sibling Cycle cryocoolers conducted with two different computer simulation codes. One code (CRYOWEISS) performs an initial analysis on the assumption of isothermal conditions in the machines and adjusts that result with decoupled loss calculations. The other code (MS*2) models fluid flows and heat transfers more realistically but ignores significant loss mechanisms, including flow friction and heat conduction through the metal of the machines. Surprisingly, MS*2 is less optimistic about performance of all machines even though it ignores losses that are modelled by CRYOWEISS. Comparison between constant-bore Stirling and Sibling machines shows that their performance is generally comparable over a range of temperatures, pressures and operating speeds. No machine was consistently superior or inferior according to both codes over the whole range of conditions studied

  12. [Risk of certain obstetric pathologies in women employed in working conditions non-complying with the current legal status on work load and working conditions appropriate for pregnant women].

    Science.gov (United States)

    Makowiec-Dabrowska, Teresa; Hanke, Wojciech; Sobala, Wojciech; Radwan-Włodarczyk, Zyta; Koszada-Włodarczyk, Wiesława

    2003-01-01

    The aim of the study was to define the incidence of prematurity and small-for-gestational age (SGA) infants in occupationally involved pregnant women, and to find out how far working conditions departing from binding regulations contribute to the risk of the development of these pathologies. The study was carried out on a representative sample of 3050 women employed for longer than one week during pregnancy in the Łódź district. An interview conducted with the subjects few days after delivery was the source of information about working conditions. The obtained information was compared with the real situation in about 10% of randomly selected workposts. A high level of consistence was observed. The study revealed that almost 60% of women work in conditions, which do not comply with the Labor Code provisions setting working conditions permissible for pregnant women. In the study group, 4.68% of prematurity and 6.15% of SGA were recorded. A 66% excess in the risk of delivering SGA infants in case of at least one factor not complying with regulations was revealed. The excess was growing with the increased number of departures from regulations and continuation of employment during pregnancy. It was estimated that the number of SGA cases would decrease by 28% if the working conditions would have met the requirements. A prolonged time of work, local vibration for > 4h/shift, forced work pace, excessive effort and forced body position during the work performance contributed mostly to the risk of pathology. Interestingly, the risk of premature delivery was lower by about 40% in women working in unsatisfactory conditions, which is attributed to termination of work immediately after the occurrence of pregnancy-threatening symptoms. Only those women whose pregnancy was not threatened with pathology could continue their work. The study revealed a quite large number of workplaces not complying with regulations on working conditions permissible for pregnant women. Therefore

  13. GAPCON-THERMAL-3 code description

    International Nuclear Information System (INIS)

    Lanning, D.D.; Mohr, C.L.; Panisko, F.E.; Stewart, K.B.

    1978-01-01

    GAPCON-3 is a computer program that predicts the thermal and mechanical behavior of an operating fuel rod during its normal lifetime. The code calculates temperatures, dimensions, stresses, and strains for the fuel and the cladding in both the radial and axial directions for each step of the user specified power history. The method of weighted residuals is for the steady state temperature calculation, and is combined with a finite difference approximation of the time derivative for transient conditions. The stress strain analysis employs an iterative axisymmetric finite element procedure that includes plasticity and creep for normal and pellet-clad mechanical interaction loads. GAPCON-3 can solve steady state and operational transient problems. Comparisons of GAPCON-3 predictions to both closed form analytical solutions and actual inpile instrumented fuel rod data have demonstrated the ability of the code to calculate fuel rod behavior. GAPCON-3 features a restart capability and an associated plot package unavailable in previous GAPCON series codes

  14. GAPCON-THERMAL-3 code description

    Energy Technology Data Exchange (ETDEWEB)

    Lanning, D.D.; Mohr, C.L.; Panisko, F.E.; Stewart, K.B.

    1978-01-01

    GAPCON-3 is a computer program that predicts the thermal and mechanical behavior of an operating fuel rod during its normal lifetime. The code calculates temperatures, dimensions, stresses, and strains for the fuel and the cladding in both the radial and axial directions for each step of the user specified power history. The method of weighted residuals is for the steady state temperature calculation, and is combined with a finite difference approximation of the time derivative for transient conditions. The stress strain analysis employs an iterative axisymmetric finite element procedure that includes plasticity and creep for normal and pellet-clad mechanical interaction loads. GAPCON-3 can solve steady state and operational transient problems. Comparisons of GAPCON-3 predictions to both closed form analytical solutions and actual inpile instrumented fuel rod data have demonstrated the ability of the code to calculate fuel rod behavior. GAPCON-3 features a restart capability and an associated plot package unavailable in previous GAPCON series codes.

  15. Software Certification - Coding, Code, and Coders

    Science.gov (United States)

    Havelund, Klaus; Holzmann, Gerard J.

    2011-01-01

    We describe a certification approach for software development that has been adopted at our organization. JPL develops robotic spacecraft for the exploration of the solar system. The flight software that controls these spacecraft is considered to be mission critical. We argue that the goal of a software certification process cannot be the development of "perfect" software, i.e., software that can be formally proven to be correct under all imaginable and unimaginable circumstances. More realistically, the goal is to guarantee a software development process that is conducted by knowledgeable engineers, who follow generally accepted procedures to control known risks, while meeting agreed upon standards of workmanship. We target three specific issues that must be addressed in such a certification procedure: the coding process, the code that is developed, and the skills of the coders. The coding process is driven by standards (e.g., a coding standard) and tools. The code is mechanically checked against the standard with the help of state-of-the-art static source code analyzers. The coders, finally, are certified in on-site training courses that include formal exams.

  16. Comparison of secondary flows predicted by a viscous code and an inviscid code with experimental data for a turning duct

    Science.gov (United States)

    Schwab, J. R.; Povinelli, L. A.

    1984-01-01

    A comparison of the secondary flows computed by the viscous Kreskovsky-Briley-McDonald code and the inviscid Denton code with benchmark experimental data for turning duct is presented. The viscous code is a fully parabolized space-marching Navier-Stokes solver while the inviscid code is a time-marching Euler solver. The experimental data were collected by Taylor, Whitelaw, and Yianneskis with a laser Doppler velocimeter system in a 90 deg turning duct of square cross-section. The agreement between the viscous and inviscid computations was generally very good for the streamwise primary velocity and the radial secondary velocity, except at the walls, where slip conditions were specified for the inviscid code. The agreement between both the computations and the experimental data was not as close, especially at the 60.0 deg and 77.5 deg angular positions within the duct. This disagreement was attributed to incomplete modelling of the vortex development near the suction surface.

  17. Modeling chemical gradients in sediments under losing and gaining flow conditions: The GRADIENT code

    Science.gov (United States)

    Boano, Fulvio; De Falco, Natalie; Arnon, Shai

    2018-02-01

    Interfaces between sediments and water bodies often represent biochemical hotspots for nutrient reactions and are characterized by steep concentration gradients of different reactive solutes. Vertical profiles of these concentrations are routinely collected to obtain information on nutrient dynamics, and simple codes have been developed to analyze these profiles and determine the magnitude and distribution of reaction rates within sediments. However, existing publicly available codes do not consider the potential contribution of water flow in the sediments to nutrient transport, and their applications to field sites with significant water-borne nutrient fluxes may lead to large errors in the estimated reaction rates. To fill this gap, the present work presents GRADIENT, a novel algorithm to evaluate distributions of reaction rates from observed concentration profiles. GRADIENT is a Matlab code that extends a previously published framework to include the role of nutrient advection, and provides robust estimates of reaction rates in sediments with significant water flow. This work discusses the theoretical basis of the method and shows its performance by comparing the results to a series of synthetic data and to laboratory experiments. The results clearly show that in systems with losing or gaining fluxes, the inclusion of such fluxes is critical for estimating local and overall reaction rates in sediments.

  18. Mental Illness Stigma Intervention in African Americans: Examining Two Delivery Methods.

    Science.gov (United States)

    Vinson, Ebony S; Abdullah, Tahirah; Brown, Tamara L

    2016-05-01

    Stigma surrounding mental illness and mental health treatment remains a significant problem, particularly among African Americans. This study sought to examine the effects of 2 intervention delivery methods in reducing reported stigma. African Americans (n = 158) were nonrandomly assigned to an in-person contact or video condition and administered a survey immediately before, after, and 2 weeks following the stigma intervention. The in vivo contact condition consisted of an African American man discussing his experiences with mental illness and psychotherapy. The session was recorded, and the recording was used for the video condition. There were no significant effects based on delivery method; however, there was a significant effect for time on stigma and help-seeking attitude measures. Further research is needed to determine the overall effectiveness of the intervention.

  19. Discussion on LDPC Codes and Uplink Coding

    Science.gov (United States)

    Andrews, Ken; Divsalar, Dariush; Dolinar, Sam; Moision, Bruce; Hamkins, Jon; Pollara, Fabrizio

    2007-01-01

    This slide presentation reviews the progress that the workgroup on Low-Density Parity-Check (LDPC) for space link coding. The workgroup is tasked with developing and recommending new error correcting codes for near-Earth, Lunar, and deep space applications. Included in the presentation is a summary of the technical progress of the workgroup. Charts that show the LDPC decoder sensitivity to symbol scaling errors are reviewed, as well as a chart showing the performance of several frame synchronizer algorithms compared to that of some good codes and LDPC decoder tests at ESTL. Also reviewed is a study on Coding, Modulation, and Link Protocol (CMLP), and the recommended codes. A design for the Pseudo-Randomizer with LDPC Decoder and CRC is also reviewed. A chart that summarizes the three proposed coding systems is also presented.

  20. Mother code specifications (Appendix to CEA report 2472)

    International Nuclear Information System (INIS)

    Pillard, Denise; Soule, Jean-Louis

    1964-12-01

    The Mother code (written in Fortran for IBM 7094) computes the integral cross section and the first two moments of energy transfer of a thermalizer. Computation organisation and methods are presented in an other document. This document presents code specifications, i.e. input data (for spectrum description, printing options, input record formats, conditions to be met by values), and results (printing formats and options, writing and punching options and formats)

  1. Examination of the accuracy of coding hospital-acquired pressure ulcer stages.

    Science.gov (United States)

    Coomer, Nicole M; McCall, Nancy T

    2013-01-01

    Pressure ulcers (PU) are considered harmful conditions that are reasonably prevented if accepted standards of care are followed. They became subject to the payment adjustment for hospitalacquired conditions (HACs) beginning October 1, 2008. We examined several aspects of the accuracy of coding for pressure ulcers under the Medicare Hospital-Acquired Condition Present on Admission (HAC-POA) Program. We used the "4010" claim format as a basis of reference to show some of the issues of the old format, such as the underreporting of pressure ulcer stages on pressure ulcer claims and how the underreporting varied by hospital characteristics. We then used the rate of Stage III and IV pressure ulcer HACs reported in the Hospital Cost and Utilization Project State Inpatient Databases data to look at the sensitivity of PU HAC-POA coding to the number of diagnosis fields. We examined Medicare claims data for FYs 2009 and 2010 to examine the degree that the presence of stage codes were underreported on pressure ulcer claims. We selected all claims with a secondary diagnosis code of pressure ulcer site (ICD-9 diagnosis codes 707.00-707.09) that were not reported as POA (POA of "N" or "U"). We then created a binary indicator for the presence of any pressure ulcer stage diagnosis code. We examine the percentage of claims with a diagnosis of a pressure ulcer site code with no accompanying pressure ulcer stage code. Our results point to underreporting of PU stages under the "4010" format and that the reporting of stage codes varied across hospital type and location. Further, our results indicate that under the "5010" format, a higher number of pressure ulcer HACs can be expected to be reported and we should expect to encounter a larger percentage of pressure ulcers incorrectly coded as POA under the new format. The combination of the capture of 25 diagnosis codes under the new "5010" format and the change from ICD-9 to ICD-10 will likely alleviate the observed underreporting of

  2. More Than Bar Codes: Integrating Global Standards-Based Bar Code Technology Into National Health Information Systems in Ethiopia and Pakistan to Increase End-to-End Supply Chain Visibility.

    Science.gov (United States)

    Hara, Liuichi; Guirguis, Ramy; Hummel, Keith; Villanueva, Monica

    2017-12-28

    The United Nations Population Fund (UNFPA) and the United States Agency for International Development (USAID) DELIVER PROJECT work together to strengthen public health commodity supply chains by standardizing bar coding under a single set of global standards. From 2015, UNFPA and USAID collaborated to pilot test how tracking and tracing of bar coded health products could be operationalized in the public health supply chains of Ethiopia and Pakistan and inform the ecosystem needed to begin full implementation. Pakistan had been using proprietary bar codes for inventory management of contraceptive supplies but transitioned to global standards-based bar codes during the pilot. The transition allowed Pakistan to leverage the original bar codes that were preprinted by global manufacturers as opposed to printing new bar codes at the central warehouse. However, barriers at lower service delivery levels prevented full realization of end-to-end data visibility. Key barriers at the district level were the lack of a digital inventory management system and absence of bar codes at the primary-level packaging level, such as single blister packs. The team in Ethiopia developed an open-sourced smartphone application that allowed the team to scan bar codes using the mobile phone's camera and to push the captured data to the country's data mart. Real-time tracking and tracing occurred from the central warehouse to the Addis Ababa distribution hub and to 2 health centers. These pilots demonstrated that standardized product identification and bar codes can significantly improve accuracy over manual stock counts while significantly streamlining the stock-taking process, resulting in efficiencies. The pilots also showed that bar coding technology by itself is not sufficient to ensure data visibility. Rather, by using global standards for identification and data capture of pharmaceuticals and medical devices, and integrating the data captured into national and global tracking systems

  3. REFLA-1D/MODE3: a computer code for reflood thermo-hydrodynamic analysis during PWR-LOCA

    International Nuclear Information System (INIS)

    Murao, Yoshio; Okubo, Tsutomu; Sugimoto, Jun; Iguchi, Tadashi; Sudoh, Takashi.

    1985-02-01

    This manual describes the REFLA-1D/MODE3 reflood system analysis code. This code can solve the core thermo-hydrodynamics under forced flooding conditions and gravity feed conditions in a system similar to FLECHT-SET Phase A. This manual describes the REFLA-1D/MODE3 models and provides application information required to utilize the code. (author)

  4. RBMK-LOCA-Analyses with the ATHLET-Code

    Energy Technology Data Exchange (ETDEWEB)

    Petry, A. [Gesellschaft fuer Anlagen- und Reaktorsicherheit (GRS) mbH Kurfuerstendamm, Berlin (Germany); Domoradov, A.; Finjakin, A. [Research and Development Institute of Power Engineering, Moscow (Russian Federation)

    1995-09-01

    The scientific technical cooperation between Germany and Russia includes the area of adaptation of several German codes for the Russian-designed RBMK-reactor. One point of this cooperation is the adaptation of the Thermal-Hydraulic code ATHLET (Analyses of the Thermal-Hydraulics of LEaks and Transients), for RBMK-specific safety problems. This paper contains a short description of a RBMK-1000 reactor circuit. Furthermore, the main features of the thermal-hydraulic code ATHLET are presented. The main assumptions for the ATHLET-RBMK model are discussed. As an example for the application, the results of test calculations concerning a guillotine type rupture of a distribution group header are presented and discussed, and the general analysis conditions are described. A comparison with corresponding RELAP-calculations is given. This paper gives an overview on some problems posed and experience by application of Western best-estimate codes for RBMK-calculations.

  5. Adaptation of multidimensional group particle tracking and particle wall-boundary condition model to the FDNS code

    Science.gov (United States)

    Chen, Y. S.; Farmer, R. C.

    1992-01-01

    A particulate two-phase flow CFD model was developed based on the FDNS code which is a pressure based predictor plus multi-corrector Navier-Stokes flow solver. Turbulence models with compressibility correction and the wall function models were employed as submodels. A finite-rate chemistry model was used for reacting flow simulation. For particulate two-phase flow simulations, a Eulerian-Lagrangian solution method using an efficient implicit particle trajectory integration scheme was developed in this study. Effects of particle-gas reaction and particle size change to agglomeration or fragmentation were not considered in this investigation. At the onset of the present study, a two-dimensional version of FDNS which had been modified to treat Lagrangian tracking of particles (FDNS-2DEL) had already been written and was operational. The FDNS-2DEL code was too slow for practical use, mainly because it had not been written in a form amenable to vectorization on the Cray, nor was the full three-dimensional form of FDNS utilized. The specific objective of this study was to reorder to calculations into long single arrays for automatic vectorization on the Cray and to implement the full three-dimensional version of FDNS to produce the FDNS-3DEL code. Since the FDNS-2DEL code was slow, a very limited number of test cases had been run with it. This study was also intended to increase the number of cases simulated to verify and improve, as necessary, the particle tracking methodology coded in FDNS.

  6. Fast dose assessment models, parameters and code under accident conditions for Qinshan Nuclear Power Plant

    International Nuclear Information System (INIS)

    Zhang, Z.Y.; Hu, E.B.; Meng, X.C.; Zhang, Y.; Yao, R.T.

    1993-01-01

    According to requirement of accident emergency plan for Qinshan Nuclear Power Plant, a Gaussian straight-line model was adopted for estimating radionuclide concentration in surface air. In addition, the effects of mountain body on atmospheric dispersion was considered. By combination of field atmospheric dispersion experiment and wind tunnel modeling test, necessary modifications have been done for some models and parameters. A computer code for assessment was written in Quick BASIC (V4.5) language. The radius of assessment region is 10 km and the code is applicable to early accident assessment. (1 tab.)

  7. Sample problem manual for benchmarking of cask analysis codes

    International Nuclear Information System (INIS)

    Glass, R.E.

    1988-02-01

    A series of problems have been defined to evaluate structural and thermal codes. These problems were designed to simulate the hypothetical accident conditions given in Title 10 of the Code of Federal Regulation, Part 71 (10CFR71) while retaining simple geometries. This produced a problem set that exercises the ability of the codes to model pertinent physical phenomena without requiring extensive use of computer resources. The solutions that are presented are consensus solutions based on computer analyses done by both national laboratories and industry in the United States, United Kingdom, France, Italy, Sweden, and Japan. The intent of this manual is to provide code users with a set of standard structural and thermal problems and solutions which can be used to evaluate individual codes. 19 refs., 19 figs., 14 tabs

  8. The potential of the Code for Sustainable Homes to deliver genuine 'sustainable energy' in the UK social housing sector

    International Nuclear Information System (INIS)

    McManus, A.; Gaterell, M.R.; Coates, L.E.

    2010-01-01

    Environmental concern in light of anthropogenic climate change will impact the housing sector as one of the major energy-consuming and carbon dioxide producing sectors. For new housing, currently the most important policy to combat this issue is the Code for Sustainable Homes. The social housing sector is under obligation to comply with these standards, which entails a significant increase in the cost of housing delivery. The sector is also under pressure to increase much-needed housebuilding, without increased funding being available. The quandary facing the sector is how to achieve both aims. Therefore any policy, such as the Code, which impacts on the ability of the sector to deliver unit numbers must be truly effective at delivering its own main aim. This paper explores the current situation, with a preliminary analysis of how the Code may not be able to deliver its 'sustainable energy' goals due to the ways in which 'low and zero carbon technologies' are assessed and how they behave in real world situations. It demonstrates that further research and policy changes are needed to deliver sustainable energy for this sector and ensure the delivery of crucial new housing is not hampered whilst also failing to meet energy goals.

  9. A restructuring of TF package for MIDAS computer code

    International Nuclear Information System (INIS)

    Park, S. H.; Song, Y. M.; Kim, D. H.

    2002-01-01

    TF package which defines some interpolation and extrapolation condition through user defined table has been restructured in MIDAS computer code. To do this, data transferring methods of current MELCOR code are modified and adopted into TF package. The data structure of the current MELCOR code using FORTRAN77 causes a difficult grasping of the meaning of the variables as well as waste of memory. New features of FORTRAN90 make it possible to allocate the storage dynamically and to use the user-defined data type, which lead to an efficient memory treatment and an easy understanding of the code. Restructuring of TF package addressed in this paper does module development and subroutine modification, and treats MELGEN which is making restart file as well as MELCOR which is processing calculation. The validation has been done by comparing the results of the modified code with those from the existing code, and it is confirmed that the results are the same. It hints that the similar approach could be extended to the entire code package. It is expected that code restructuring will accelerate the code domestication thanks to direct understanding of each variable and easy implementation of modified or newly developed models

  10. An axisymmetric gravitational collapse code

    Energy Technology Data Exchange (ETDEWEB)

    Choptuik, Matthew W [CIAR Cosmology and Gravity Program, Department of Physics and Astronomy, University of British Columbia, Vancouver BC, V6T 1Z1 (Canada); Hirschmann, Eric W [Department of Physics and Astronomy, Brigham Young University, Provo, UT 84604 (United States); Liebling, Steven L [Southampton College, Long Island University, Southampton, NY 11968 (United States); Pretorius, Frans [Theoretical Astrophysics, California Institute of Technology, Pasadena, CA 91125 (United States)

    2003-05-07

    We present a new numerical code designed to solve the Einstein field equations for axisymmetric spacetimes. The long-term goal of this project is to construct a code that will be capable of studying many problems of interest in axisymmetry, including gravitational collapse, critical phenomena, investigations of cosmic censorship and head-on black-hole collisions. Our objective here is to detail the (2+1)+1 formalism we use to arrive at the corresponding system of equations and the numerical methods we use to solve them. We are able to obtain stable evolution, despite the singular nature of the coordinate system on the axis, by enforcing appropriate regularity conditions on all variables and by adding numerical dissipation to hyperbolic equations.

  11. An axisymmetric gravitational collapse code

    International Nuclear Information System (INIS)

    Choptuik, Matthew W; Hirschmann, Eric W; Liebling, Steven L; Pretorius, Frans

    2003-01-01

    We present a new numerical code designed to solve the Einstein field equations for axisymmetric spacetimes. The long-term goal of this project is to construct a code that will be capable of studying many problems of interest in axisymmetry, including gravitational collapse, critical phenomena, investigations of cosmic censorship and head-on black-hole collisions. Our objective here is to detail the (2+1)+1 formalism we use to arrive at the corresponding system of equations and the numerical methods we use to solve them. We are able to obtain stable evolution, despite the singular nature of the coordinate system on the axis, by enforcing appropriate regularity conditions on all variables and by adding numerical dissipation to hyperbolic equations

  12. Treatment of isomers in nucleosynthesis codes

    Science.gov (United States)

    Reifarth, René; Fiebiger, Stefan; Göbel, Kathrin; Heftrich, Tanja; Kausch, Tanja; Köppchen, Christoph; Kurtulgil, Deniz; Langer, Christoph; Thomas, Benedikt; Weigand, Mario

    2018-03-01

    The decay properties of long-lived excited states (isomers) can have a significant impact on the destruction channels of isotopes under stellar conditions. In sufficiently hot environments, the population of isomers can be altered via thermal excitation or de-excitation. If the corresponding lifetimes are of the same order of magnitude as the typical time scales of the environment, the isomers have to be treated explicitly. We present a general approach to the treatment of isomers in stellar nucleosynthesis codes and discuss a few illustrative examples. The corresponding code is available online at http://exp-astro.de/isomers/.

  13. IFR code for secondary particle dynamics

    International Nuclear Information System (INIS)

    Teague, M.R.; Yu, S.S.

    1985-01-01

    A numerical simulation has been constructed to obtain a detailed, quantitative estimate of the electromagnetic fields and currents existing in the Advanced Test Accelerator under conditions of laser guiding. The code treats the secondary electrons by particle simulation and the beam dynamics by a time-dependent envelope model. The simulation gives a fully relativistic description of secondary electrons moving in self-consistent electromagnetic fields. The calculations are made using coordinates t, x, y, z for the electrons and t, ct-z, r for the axisymmetric electromagnetic fields and currents. Code results, showing in particular current enhancement effects, will be given

  14. Shadowfax: Moving mesh hydrodynamical integration code

    Science.gov (United States)

    Vandenbroucke, Bert

    2016-05-01

    Shadowfax simulates galaxy evolution. Written in object-oriented modular C++, it evolves a mixture of gas, subject to the laws of hydrodynamics and gravity, and any collisionless fluid only subject to gravity, such as cold dark matter or stars. For the hydrodynamical integration, it makes use of a (co-) moving Lagrangian mesh. The code has a 2D and 3D version, contains utility programs to generate initial conditions and visualize simulation snapshots, and its input/output is compatible with a number of other simulation codes, e.g. Gadget2 (ascl:0003.001) and GIZMO (ascl:1410.003).

  15. Three Dimensional Numerical Code for the Expanding Flat Universe

    Directory of Open Access Journals (Sweden)

    Kyoung W. Min

    1987-12-01

    Full Text Available The current distribution of galaxies may contain clues to the condition of the universe when the galaxies condensed and to the nature of the subsequent expansion of the universe. The development of this large scale structure can be studied by employing N-body computer simulations. The present paper describes the code developed for this purpose. The computer code calculates the motion of collisionless matter action under the force of gravity in an expanding flat universe. The test run of the code shows the error less than 0.5% in 100 iterations.

  16. Fault tree analysis. Implementation of the WAM-codes

    International Nuclear Information System (INIS)

    Bento, J.P.; Poern, K.

    1979-07-01

    The report describes work going on at Studsvik at the implementation of the WAM code package for fault tree analysis. These codes originally developed under EPRI contract by Sciences Applications Inc, allow, in contrast with other fault tree codes, all Boolean operations, thus allowing modeling of ''NOT'' conditions and dependent components. To concretize the implementation of these codes, the auxiliary feed-water system of the Swedish BWR Oskarshamn 2 was chosen for the reliability analysis. For this system, both the mean unavailability and the probability density function of the top event - undesired event - of the system fault tree were calculated, the latter using a Monte-Carlo simulation technique. The present study is the first part of a work performed under contract with the Swedish Nuclear Power Inspectorate. (author)

  17. Analysis of the SPERT III E-core experiment using the EUREKA-2 code

    International Nuclear Information System (INIS)

    Harami, Taikan; Uemura, Mutsumi; Ohnishi, Nobuaki

    1986-09-01

    EUREKA-2, a coupled nuclear thermal hydrodynamic kinetic code, was adapted for the testing of models and methods. Code evaluations were made with the reactivity addition experiments of the SPERT III E-Core, a slightly enriched oxide core. The code was tested for non damaging power excursions including a wide range of initial operating conditions, such as cold-startup, hot-startup, hot-standby and operating-power initial conditions. Comparisons resulted in a good agreement within the experimental errors between calculated and experimental power, energy, reactivity and clad surface temperature. (author)

  18. Modelling of WWER-440 fuel rod behaviour under operational conditions with the PIN-micro code

    International Nuclear Information System (INIS)

    Stefanova, S.; Vitkova, M.; Simeonova, V.; Passage, G.; Manolova, M.; Haralampieva, Z.; Scheglov, A.; Proselkov, V.

    1997-01-01

    The report summarizes the first practical experience obtained by fuel rod performance modelling at the Institute for Nuclear Research and Nuclear Energy, Bulgarian Academy of Sciences. The results of application of the PIN-micro code and the code modification PINB1 for thermomechanical analysis of WWER-440 fuel assemblies (FAs) are presented. The aim of this analysis is to study the fuel rod behaviour of the operating WWER reactors. The performance of two FAs with maximal linear power and varying geometrical and technological parameters is analyzed. On the basis of recent publications on WWER fuel performance modelling at extended burnup, a modified PINB1 version of the standard PIN-micro code is shortly described and applied for the selected FAs. Comparison of the calculated results is performed. The PINB1 version predicts higher fuel temperatures and more adequate FGR rate, accounting for the extended burnup. The results presented in this paper prove the existence of sufficient safety margins, for the fuel performance limiting parameters during the whole considered period of core operation. (author). 8 refs, 16 figs, 1 tab

  19. Modelling of WWER-440 fuel rod behaviour under operational conditions with the PIN-micro code

    Energy Technology Data Exchange (ETDEWEB)

    Stefanova, S; Vitkova, M; Simeonova, V; Passage, G; Manolova, M [Institute for Nuclear Research and Nuclear Energy, Sofia (Bulgaria); Haralampieva, Z [National Electric Company Ltd., Kozloduy (Bulgaria); Scheglov, A; Proselkov, V [Institute of Nuclear Reactors, RSC Kurchatov Inst., Moscow (Russian Federation)

    1997-08-01

    The report summarizes the first practical experience obtained by fuel rod performance modelling at the Institute for Nuclear Research and Nuclear Energy, Bulgarian Academy of Sciences. The results of application of the PIN-micro code and the code modification PINB1 for thermomechanical analysis of WWER-440 fuel assemblies (FAs) are presented. The aim of this analysis is to study the fuel rod behaviour of the operating WWER reactors. The performance of two FAs with maximal linear power and varying geometrical and technological parameters is analyzed. On the basis of recent publications on WWER fuel performance modelling at extended burnup, a modified PINB1 version of the standard PIN-micro code is shortly described and applied for the selected FAs. Comparison of the calculated results is performed. The PINB1 version predicts higher fuel temperatures and more adequate FGR rate, accounting for the extended burnup. The results presented in this paper prove the existence of sufficient safety margins, for the fuel performance limiting parameters during the whole considered period of core operation. (author). 8 refs, 16 figs, 1 tab.

  20. New quantum codes constructed from quaternary BCH codes

    Science.gov (United States)

    Xu, Gen; Li, Ruihu; Guo, Luobin; Ma, Yuena

    2016-10-01

    In this paper, we firstly study construction of new quantum error-correcting codes (QECCs) from three classes of quaternary imprimitive BCH codes. As a result, the improved maximal designed distance of these narrow-sense imprimitive Hermitian dual-containing quaternary BCH codes are determined to be much larger than the result given according to Aly et al. (IEEE Trans Inf Theory 53:1183-1188, 2007) for each different code length. Thus, families of new QECCs are newly obtained, and the constructed QECCs have larger distance than those in the previous literature. Secondly, we apply a combinatorial construction to the imprimitive BCH codes with their corresponding primitive counterpart and construct many new linear quantum codes with good parameters, some of which have parameters exceeding the finite Gilbert-Varshamov bound for linear quantum codes.

  1. Nano/Micro Formulations for Bacteriophage Delivery.

    Science.gov (United States)

    Cortés, Pilar; Cano-Sarabia, Mary; Colom, Joan; Otero, Jennifer; Maspoch, Daniel; Llagostera, Montserrat

    2018-01-01

    Encapsulation methodologies allow the protection of bacteriophages for overcoming critical environmental conditions. Moreover, they improve the stability and the controlled delivery of bacteriophages which is of great innovative value in bacteriophage therapy. Here, two different encapsulation methodologies of bacteriophages are described using two biocompatible materials: a lipid cationic mixture and a combination of alginate with the antacid CaCO 3 . To perform bacteriophage encapsulation, a purified lysate highly concentrated (around 10 10 -10 11  pfu/mL) is necessary, and to dispose of a specific equipment. Both methodologies have been successfully applied for encapsulating Salmonella bacteriophages with different morphologies. Also, the material employed does not modify the antibacterial action of bacteriophages. Moreover, both technologies can also be adapted to any bacteriophage and possibly to any delivery route for bacteriophage therapy.

  2. Development of 2-d cfd code

    International Nuclear Information System (INIS)

    Mirza, S.A.

    1999-01-01

    In the present study, a two-dimensional computer code has been developed in FORTRAN using CFD technique, which is basically a numerical scheme. This computer code solves the Navier Stokes equations and continuity equation to find out the velocity and pressure fields within a given domain. This analysis has been done for the developed within a square cavity driven by the upper wall which has become a bench mark for testing and comparing the newly developed numerical schemes. Before to handle this task, different one-dimensional cases have been studied by CFD technique and their FORTRAN programs written. The cases studied are Couette flow, Poiseuille flow with and without using symmetric boundary condition. Finally a comparison between CFD results and analytical results has also been made. For the cavity flow the results from the developed code have been obtained for different Reynolds numbers which are finally presented in the form of velocity vectors. The comparison of the developed code results have been made with the results obtained from the share ware version of a commercially available code for Reynolds number of 10.0. The disagreement in the results quantitatively and qualitatively at some grid points of the calculation domain have been discussed and future recommendations in this regard have also been made. (author)

  3. The development and application of a sub-channel code in ocean environment

    International Nuclear Information System (INIS)

    Wu, Pan; Shan, Jianqiang; Xiang, Xiong; Zhang, Bo; Gou, Junli; Zhang, Bin

    2016-01-01

    Highlights: • A sub-channel code named ATHAS/OE is developed for nuclear reactors in ocean environment. • ATHAS/OE is verified by another modified sub-channel code based on COBRA-IV. • ATHAS/OE is used to analyze thermal hydraulic of a typical SMR in heaving and rolling motion. • Calculation results show that ocean condition affect the thermal hydraulic of a reactor significantly. - Abstract: An upgraded version of ATHAS sub-channel code ATHAS/OE is developed for the investigation of the thermal hydraulic behavior of nuclear reactor core in ocean environment with consideration of heaving and rolling motion effect. The code is verified by another modified sub-channel code based on COBRA-IV and used to analyze the thermal hydraulic characteristics of a typical SMR under heaving and rolling motion condition. The calculation results show that the heaving and rolling motion affect the thermal hydraulic behavior of a reactor significantly.

  4. Electromagnetic simulations of the ASDEX Upgrade ICRF Antenna with the TOPICA code

    International Nuclear Information System (INIS)

    Krivska, A.; Milanesio, D.; Bobkov, V.; Braun, F.; Noterdaeme, J.-M.

    2009-01-01

    Accurate and efficient simulation tools are necessary to optimize the ICRF antenna design for a set of operational conditions. The TOPICA code was developed for performance prediction and for the analysis of ICRF antenna systems in the presence of plasma, given realistic antenna geometries. Fully 3D antenna geometries can be adopted in TOPICA, just as in available commercial codes. But while those commercial codes cannot operate with a plasma loading, the TOPICA code correctly accounts for realistic plasma loading conditions, by means of the coupling with 1D FELICE code. This paper presents the evaluation of the electric current distribution on the structure, of the parallel electric field in the region between the straps and the plasma and the computation of sheaths driving RF potentials. Results of TOPICA simulations will help to optimize and re-design the ICRF ASDEX Upgrade antenna in order to reduce tungsten (W) sputtering attributed to the rectified sheath effect during ICRF operation.

  5. Methods and metrics challenges of delivery-system research

    Directory of Open Access Journals (Sweden)

    Alexander Jeffrey A

    2012-03-01

    Full Text Available Abstract Background Many delivery-system interventions are fundamentally about change in social systems (both planned and unplanned. This systems perspective raises a number of methodological challenges for studying the effects of delivery-system change--particularly for answering questions related to whether the change will work under different conditions and how the change is integrated (or not into the operating context of the delivery system. Methods The purpose of this paper is to describe the methodological and measurement challenges posed by five key issues in delivery-system research: (1 modeling intervention context; (2 measuring readiness for change; (3 assessing intervention fidelity and sustainability; (4 assessing complex, multicomponent interventions; and (5 incorporating time in delivery-system models to discuss recommendations for addressing these issues. For each issue, we provide recommendations for how research may be designed and implemented to overcome these challenges. Results and conclusions We suggest that a more refined understanding of the mechanisms underlying delivery-system interventions (treatment theory and the ways in which outcomes for different classes of individuals change over time are fundamental starting points for capturing the heterogeneity in samples of individuals exposed to delivery-system interventions. To support the research recommendations outlined in this paper and to advance understanding of the "why" and "how" questions of delivery-system change and their effects, funding agencies should consider supporting studies with larger organizational sample sizes; longer duration; and nontraditional, mixed-methods designs. A version of this paper was prepared under contract with the Agency for Healthcare Research and Quality (AHRQ, US Department of Health and Human Services for presentation and discussion at a meeting on "The Challenge and Promise of Delivery System Research," held in Sterling, VA, on

  6. Entanglement-assisted quantum MDS codes from negacyclic codes

    Science.gov (United States)

    Lu, Liangdong; Li, Ruihu; Guo, Luobin; Ma, Yuena; Liu, Yang

    2018-03-01

    The entanglement-assisted formalism generalizes the standard stabilizer formalism, which can transform arbitrary classical linear codes into entanglement-assisted quantum error-correcting codes (EAQECCs) by using pre-shared entanglement between the sender and the receiver. In this work, we construct six classes of q-ary entanglement-assisted quantum MDS (EAQMDS) codes based on classical negacyclic MDS codes by exploiting two or more pre-shared maximally entangled states. We show that two of these six classes q-ary EAQMDS have minimum distance more larger than q+1. Most of these q-ary EAQMDS codes are new in the sense that their parameters are not covered by the codes available in the literature.

  7. Visualizing code and coverage changes for code review

    NARCIS (Netherlands)

    Oosterwaal, Sebastiaan; van Deursen, A.; De Souza Coelho, R.; Sawant, A.A.; Bacchelli, A.

    2016-01-01

    One of the tasks of reviewers is to verify that code modifications are well tested. However, current tools offer little support in understanding precisely how changes to the code relate to changes to the tests. In particular, it is hard to see whether (modified) test code covers the changed code.

  8. Homological stabilizer codes

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, Jonas T., E-mail: jonastyleranderson@gmail.com

    2013-03-15

    In this paper we define homological stabilizer codes on qubits which encompass codes such as Kitaev's toric code and the topological color codes. These codes are defined solely by the graphs they reside on. This feature allows us to use properties of topological graph theory to determine the graphs which are suitable as homological stabilizer codes. We then show that all toric codes are equivalent to homological stabilizer codes on 4-valent graphs. We show that the topological color codes and toric codes correspond to two distinct classes of graphs. We define the notion of label set equivalencies and show that under a small set of constraints the only homological stabilizer codes without local logical operators are equivalent to Kitaev's toric code or to the topological color codes. - Highlights: Black-Right-Pointing-Pointer We show that Kitaev's toric codes are equivalent to homological stabilizer codes on 4-valent graphs. Black-Right-Pointing-Pointer We show that toric codes and color codes correspond to homological stabilizer codes on distinct graphs. Black-Right-Pointing-Pointer We find and classify all 2D homological stabilizer codes. Black-Right-Pointing-Pointer We find optimal codes among the homological stabilizer codes.

  9. MIDAS/PK code development using point kinetics model

    International Nuclear Information System (INIS)

    Song, Y. M.; Park, S. H.

    1999-01-01

    In this study, a MIDAS/PK code has been developed for analyzing the ATWS (Anticipated Transients Without Scram) which can be one of severe accident initiating events. The MIDAS is an integrated computer code based on the MELCOR code to develop a severe accident risk reduction strategy by Korea Atomic Energy Research Institute. In the mean time, the Chexal-Layman correlation in the current MELCOR, which was developed under a BWR condition, is appeared to be inappropriate for a PWR. So as to provide ATWS analysis capability to the MIDAS code, a point kinetics module, PKINETIC, has first been developed as a stand-alone code whose reference model was selected from the current accident analysis codes. In the next step, the MIDAS/PK code has been developed via coupling PKINETIC with the MIDAS code by inter-connecting several thermal hydraulic parameters between the two codes. Since the major concern in the ATWS analysis is the primary peak pressure during the early few minutes into the accident, the peak pressure from the PKINETIC module and the MIDAS/PK are compared with the RETRAN calculations showing a good agreement between them. The MIDAS/PK code is considered to be valuable for analyzing the plant response during ATWS deterministically, especially for the early domestic Westinghouse plants which rely on the operator procedure instead of an AMSAC (ATWS Mitigating System Actuation Circuitry) against ATWS. This capability of ATWS analysis is also important from the view point of accident management and mitigation

  10. Interdelivery weight gain and risk of cesarean delivery following a prior vaginal delivery.

    Science.gov (United States)

    Dude, Annie M; Lane-Cordova, Abbi D; Grobman, William A

    2017-09-01

    Approximately one third of all deliveries in the United States are via cesarean. Previous research indicates weight gain during pregnancy is associated with an increased risk of cesarean delivery. It remains unclear, however, whether and to what degree weight gain between deliveries (ie, interdelivery weight gain) is associated with cesarean delivery in a subsequent pregnancy following a vaginal delivery. The objective of the study was to determine whether interdelivery weight gain is associated with an increased risk of intrapartum cesarean delivery following a vaginal delivery. This was a case-control study of women who had 2 consecutive singleton births of at least 36 weeks' gestation between 2005 and 2016, with a vaginal delivery in the index pregnancy. Women were excluded if they had a contraindication to a trial of labor (eg, fetal malpresentation or placenta previa) in the subsequent pregnancy. Maternal characteristics and delivery outcomes for both pregnancies were abstracted from the medical record. Maternal weight gain between deliveries was measured as the change in body mass index at delivery. Women who underwent a subsequent cesarean delivery were compared with those who had a repeat vaginal delivery using χ 2 statistics for categorical variables and Student t tests or analysis of variance for continuous variables. Multivariable logistic regression was used to determine whether interdelivery weight gain remained independently associated with intrapartum cesarean delivery after adjusting for potential confounders. Of 10,396 women who met eligibility criteria and had complete data, 218 (2.1%) had a cesarean delivery in the subsequent pregnancy. Interdelivery weight gain was significantly associated with cesarean delivery and remained significant in multivariable analysis for women with a body mass index increase of at least 2 kg/m 2 (adjusted odds ratio, 1.53, 95% confidence interval, 1.03-2.27 for a body mass index increase of 2 kg/m 2 to gained 2 kg

  11. SPECTRAL AMPLITUDE CODING OCDMA SYSTEMS USING ENHANCED DOUBLE WEIGHT CODE

    Directory of Open Access Journals (Sweden)

    F.N. HASOON

    2006-12-01

    Full Text Available A new code structure for spectral amplitude coding optical code division multiple access systems based on double weight (DW code families is proposed. The DW has a fixed weight of two. Enhanced double-weight (EDW code is another variation of a DW code family that can has a variable weight greater than one. The EDW code possesses ideal cross-correlation properties and exists for every natural number n. A much better performance can be provided by using the EDW code compared to the existing code such as Hadamard and Modified Frequency-Hopping (MFH codes. It has been observed that theoretical analysis and simulation for EDW is much better performance compared to Hadamard and Modified Frequency-Hopping (MFH codes.

  12. Comparison of strongly heat-driven flow codes for unsaturated media

    International Nuclear Information System (INIS)

    Updegraff, C.D.

    1989-08-01

    Under the sponsorship of the US Nuclear Regulatory Commission, Sandia National Laboratories (SNL) is developing a performance assessment methodology for the analysis of long-term disposal of high-level radioactive waste (HLW) in unsaturated welded tuff. As part of this effort, SNL evaluated existing strongly heat-driven flow computer codes for simulating ground-water flow in unsaturated media. The three codes tested, NORIA, PETROS, and TOUGH, were compared against a suite of problems for which analytical and numerical solutions or experimental results exist. The problems were selected to test the abilities of the codes to simulate situations ranging from simple, uncoupled processes, such as two-phase flow or heat transfer, to fully coupled processes, such as vaporization caused by high temperatures. In general, all three codes were found to be difficult to use because of (1) built-in time stepping criteria, (2) the treatment of boundary conditions, and (3) handling of evaporation/condensation problems. A drawback of the study was that adequate problems related to expected repository conditions were not available in the literature. Nevertheless, the results of this study suggest the need for thorough investigations of the impact of heat on the flow field in the vicinity of an unsaturated HLW repository. Recommendations are to develop a new flow code combining the best features of these three codes and eliminating the worst ones. 19 refs., 49 figs

  13. The fuel performance code future

    International Nuclear Information System (INIS)

    Ronchi, C.; Van de Laar, J.

    1988-01-01

    The paper describes the LWR version of the fuel performance code FUTURE, which was recently developed to calculate the fuel response (swelling, cladding deformation, release) to reactor transient conditions, starting from a broad-based description of the processes of major concern. The main physical models assumed are presented together with the scheme of the computer program

  14. Analysis of pipe stress using CAESAR II code

    International Nuclear Information System (INIS)

    Sitandung, Y.B.; Bandriyana, B.

    2002-01-01

    Analysis of this piping stress with the purpose of knowing stress distribution piping system in order to determine pipe supports configuration. As an example of analysis, Gas Exchanger to Warm Separator Line was chosen with, input data was firstly prepared in a document, i.e. piping analysis specification that its content named as pipe characteristics, material properties, operation conditions, guide equipment's and so on. Analysis result such as stress, load, displacement and the use support type were verified based on requirements in the code, standard, and regularities were suitable with piping system condition analyzed. As the proof that piping system is in safety condition, it can be indicated from analysis results (actual loads) which still under allowable load. From the analysis steps that have been done CAESAR II code fulfill requirements to be used as a tool of piping stress analysis as well as nuclear and non nuclear installation piping system

  15. eDelivery

    Data.gov (United States)

    US Agency for International Development — eDelivery provides the electronic packaging and delivery of closed and complete OPM investigation files to government agencies, including USAID, in a secure manner....

  16. Automated uncertainty analysis methods in the FRAP computer codes

    International Nuclear Information System (INIS)

    Peck, S.O.

    1980-01-01

    A user oriented, automated uncertainty analysis capability has been incorporated in the Fuel Rod Analysis Program (FRAP) computer codes. The FRAP codes have been developed for the analysis of Light Water Reactor fuel rod behavior during steady state (FRAPCON) and transient (FRAP-T) conditions as part of the United States Nuclear Regulatory Commission's Water Reactor Safety Research Program. The objective of uncertainty analysis of these codes is to obtain estimates of the uncertainty in computed outputs of the codes is to obtain estimates of the uncertainty in computed outputs of the codes as a function of known uncertainties in input variables. This paper presents the methods used to generate an uncertainty analysis of a large computer code, discusses the assumptions that are made, and shows techniques for testing them. An uncertainty analysis of FRAP-T calculated fuel rod behavior during a hypothetical loss-of-coolant transient is presented as an example and carried through the discussion to illustrate the various concepts

  17. Detected-jump-error-correcting quantum codes, quantum error designs, and quantum computation

    International Nuclear Information System (INIS)

    Alber, G.; Mussinger, M.; Beth, Th.; Charnes, Ch.; Delgado, A.; Grassl, M.

    2003-01-01

    The recently introduced detected-jump-correcting quantum codes are capable of stabilizing qubit systems against spontaneous decay processes arising from couplings to statistically independent reservoirs. These embedded quantum codes exploit classical information about which qubit has emitted spontaneously and correspond to an active error-correcting code embedded in a passive error-correcting code. The construction of a family of one-detected-jump-error-correcting quantum codes is shown and the optimal redundancy, encoding, and recovery as well as general properties of detected-jump-error-correcting quantum codes are discussed. By the use of design theory, multiple-jump-error-correcting quantum codes can be constructed. The performance of one-jump-error-correcting quantum codes under nonideal conditions is studied numerically by simulating a quantum memory and Grover's algorithm

  18. Current lead thermal analysis code 'CURRENT'

    International Nuclear Information System (INIS)

    Yamaguchi, Masahito; Tada, Eisuke; Shimamoto, Susumu; Hata, Kenichiro.

    1985-08-01

    Large gas-cooled current lead with the capacity more than 30 kA and 22 kV is required for superconducting toroidal and poloidal coils for fusion application. The current lead is used to carry electrical current from the power supply system at room temperature to the superconducting coil at 4 K. Accordingly, the thermal performance of the current lead is significantly important to determine the heat load requirements of the coil system at 4 K. Japan Atomic Energy Research Institute (JAERI) has being developed the large gas-cooled current leads with the optimum condition in which the heat load is around 1 W per 1 kA at 4 K. In order to design the current lead with the optimum thermal performances, JAERI developed thermal analysis code named as ''CURRENT'' which can theoretically calculate the optimum geometric shape and cooling conditions of the current lead. The basic equations and the instruction manual of the analysis code are described in this report. (author)

  19. Linking CATHENA with other computer codes through a remote process

    Energy Technology Data Exchange (ETDEWEB)

    Vasic, A.; Hanna, B.N.; Waddington, G.M. [Atomic Energy of Canada Limited, Chalk River, Ontario (Canada); Sabourin, G. [Atomic Energy of Canada Limited, Montreal, Quebec (Canada); Girard, R. [Hydro-Quebec, Montreal, Quebec (Canada)

    2005-07-01

    'Full text:' CATHENA (Canadian Algorithm for THErmalhydraulic Network Analysis) is a computer code developed by Atomic Energy of Canada Limited (AECL). The code uses a transient, one-dimensional, two-fluid representation of two-phase flow in piping networks. CATHENA is used primarily for the analysis of postulated upset conditions in CANDU reactors; however, the code has found a wider range of applications. In the past, the CATHENA thermalhydraulics code included other specialized codes, i.e. ELOCA and the Point LEPreau CONtrol system (LEPCON) as callable subroutine libraries. The combined program was compiled and linked as a separately named code. This code organizational process is not suitable for independent development, maintenance, validation and version tracking of separate computer codes. The alternative solution to provide code development independence is to link CATHENA to other computer codes through a Parallel Virtual Machine (PVM) interface process. PVM is a public domain software package, developed by Oak Ridge National Laboratory and enables a heterogeneous collection of computers connected by a network to be used as a single large parallel machine. The PVM approach has been well accepted by the global computing community and has been used successfully for solving large-scale problems in science, industry, and business. Once development of the appropriate interface for linking independent codes through PVM is completed, future versions of component codes can be developed, distributed separately and coupled as needed by the user. This paper describes the coupling of CATHENA to the ELOCA-IST and the TROLG2 codes through a PVM remote process as an illustration of possible code connections. ELOCA (Element Loss Of Cooling Analysis) is the Industry Standard Toolset (IST) code developed by AECL to simulate the thermo-mechanical response of CANDU fuel elements to transient thermalhydraulics boundary conditions. A separate ELOCA driver program

  20. Linking CATHENA with other computer codes through a remote process

    International Nuclear Information System (INIS)

    Vasic, A.; Hanna, B.N.; Waddington, G.M.; Sabourin, G.; Girard, R.

    2005-01-01

    'Full text:' CATHENA (Canadian Algorithm for THErmalhydraulic Network Analysis) is a computer code developed by Atomic Energy of Canada Limited (AECL). The code uses a transient, one-dimensional, two-fluid representation of two-phase flow in piping networks. CATHENA is used primarily for the analysis of postulated upset conditions in CANDU reactors; however, the code has found a wider range of applications. In the past, the CATHENA thermalhydraulics code included other specialized codes, i.e. ELOCA and the Point LEPreau CONtrol system (LEPCON) as callable subroutine libraries. The combined program was compiled and linked as a separately named code. This code organizational process is not suitable for independent development, maintenance, validation and version tracking of separate computer codes. The alternative solution to provide code development independence is to link CATHENA to other computer codes through a Parallel Virtual Machine (PVM) interface process. PVM is a public domain software package, developed by Oak Ridge National Laboratory and enables a heterogeneous collection of computers connected by a network to be used as a single large parallel machine. The PVM approach has been well accepted by the global computing community and has been used successfully for solving large-scale problems in science, industry, and business. Once development of the appropriate interface for linking independent codes through PVM is completed, future versions of component codes can be developed, distributed separately and coupled as needed by the user. This paper describes the coupling of CATHENA to the ELOCA-IST and the TROLG2 codes through a PVM remote process as an illustration of possible code connections. ELOCA (Element Loss Of Cooling Analysis) is the Industry Standard Toolset (IST) code developed by AECL to simulate the thermo-mechanical response of CANDU fuel elements to transient thermalhydraulics boundary conditions. A separate ELOCA driver program starts, ends

  1. Patient Involvement in Safe Delivery: A Qualitative Study.

    Science.gov (United States)

    Olfati, Forozun; Asefzadeh, Saeid; Changizi, Nasrin; Keramat, Afsaneh; Yunesian, Masud

    2015-09-28

    Patient involvement in safe delivery planning is considered important yet not widely practiced. The present study aimed at identifythe factors that affect patient involvementin safe delivery, as recommended by parturient women. This study was part of a qualitative research conducted by content analysis method and purposive sampling in 2013.The data were collected through 63 semi-structured interviews in4 hospitalsand analyzed using thematic content analysis. The participants in this research were women before discharge and after delivery. Findings were analyzed using Colaizzi's method. Four categories of factors that could affect patient involvement in safe delivery emerged from our analysis: patient-related (true and false beliefs, literacy, privacy, respect for patient), illness-related (pain, type of delivery, patient safety incidents), health care professional-relatedand task-related factors (behavior, monitoring &training), health care setting-related (financial aspects, facilities). More research is needed to explore the factors affecting the participation of mothers. It is therefore, recommended to: 1) take notice of mother education, their husbands, midwives and specialists; 2) provide pregnant women with insurance coverage from the outset of pregnancy, especially during prenatal period; 3) form a labor pain committee consisting of midwives, obstetricians, and anesthesiologists in order to identify the preferred painless labor methods based on the existing facilities and conditions, 4) carry out research on observing patients' privacy and dignity; 5) pay more attention on the factors affecting cesarean.

  2. Hybrid microscopic depletion model in nodal code DYN3D

    International Nuclear Information System (INIS)

    Bilodid, Y.; Kotlyar, D.; Shwageraus, E.; Fridman, E.; Kliem, S.

    2016-01-01

    Highlights: • A new hybrid method of accounting for spectral history effects is proposed. • Local concentrations of over 1000 nuclides are calculated using micro depletion. • The new method is implemented in nodal code DYN3D and verified. - Abstract: The paper presents a general hybrid method that combines the micro-depletion technique with correction of micro- and macro-diffusion parameters to account for the spectral history effects. The fuel in a core is subjected to time- and space-dependent operational conditions (e.g. coolant density), which cannot be predicted in advance. However, lattice codes assume some average conditions to generate cross sections (XS) for nodal diffusion codes such as DYN3D. Deviation of local operational history from average conditions leads to accumulation of errors in XS, which is referred as spectral history effects. Various methods to account for the spectral history effects, such as spectral index, burnup-averaged operational parameters and micro-depletion, were implemented in some nodal codes. Recently, an alternative method, which characterizes fuel depletion state by burnup and 239 Pu concentration (denoted as Pu-correction) was proposed, implemented in nodal code DYN3D and verified for a wide range of history effects. The method is computationally efficient, however, it has applicability limitations. The current study seeks to improve the accuracy and applicability range of Pu-correction method. The proposed hybrid method combines the micro-depletion method with a XS characterization technique similar to the Pu-correction method. The method was implemented in DYN3D and verified on multiple test cases. The results obtained with DYN3D were compared to those obtained with Monte Carlo code Serpent, which was also used to generate the XS. The observed differences are within the statistical uncertainties.

  3. UAV Delivery Monitoring System

    Directory of Open Access Journals (Sweden)

    San Khin Thida

    2018-01-01

    Full Text Available UAV-based delivery systems are increasingly being used in the logistics field, particularly to achieve faster last-mile delivery. This study develops a UAV delivery system that manages delivery order assignments, autonomous flight operation, real time control for UAV flights, and delivery status tracking. To manage the delivery item assignments, we apply the concurrent scheduler approach with a genetic algorithm. The present paper describes real time flight data based on a micro air vehicle communication protocol (MAVLink. It also presents the detailed hardware components used for the field tests. Finally, we provide UAV component analysis to choose the suitable components for delivery in terms of battery capacity, flight time, payload weight and motor thrust ratio.

  4. Interactive Video Coding and Transmission over Heterogeneous Wired-to-Wireless IP Networks Using an Edge Proxy

    Directory of Open Access Journals (Sweden)

    Modestino James W

    2004-01-01

    Full Text Available Digital video delivered over wired-to-wireless networks is expected to suffer quality degradation from both packet loss and bit errors in the payload. In this paper, the quality degradation due to packet loss and bit errors in the payload are quantitatively evaluated and their effects are assessed. We propose the use of a concatenated forward error correction (FEC coding scheme employing Reed-Solomon (RS codes and rate-compatible punctured convolutional (RCPC codes to protect the video data from packet loss and bit errors, respectively. Furthermore, the performance of a joint source-channel coding (JSCC approach employing this concatenated FEC coding scheme for video transmission is studied. Finally, we describe an improved end-to-end architecture using an edge proxy in a mobile support station to implement differential error protection for the corresponding channel impairments expected on the two networks. Results indicate that with an appropriate JSCC approach and the use of an edge proxy, FEC-based error-control techniques together with passive error-recovery techniques can significantly improve the effective video throughput and lead to acceptable video delivery quality over time-varying heterogeneous wired-to-wireless IP networks.

  5. Nanoparticle bioconjugate for controlled cellular delivery of doxorubicin

    Science.gov (United States)

    Sangtani, Ajmeeta; Petryayeva, Eleonora; Wu, Miao; Susumu, Kimihiro; Oh, Eunkeu; Huston, Alan L.; Lasarte-Aragones, Guillermo; Medintz, Igor L.; Algar, W. Russ; Delehanty, James B.

    2018-02-01

    Nanoparticle (NP)-mediated drug delivery offers the potential to overcome limitations of systemic delivery, including the ability to specifically target cargo and control release of NP-associated drug cargo. Doxorubicin (DOX) is a widely used FDA-approved cancer therapeutic; however, multiple side effects limit its utility. Thus, there is wide interest in modulating toxicity after cell delivery. Our goal here was to realize a NP-based DOX-delivery system that can modulate drug toxicity by controlling the release kinetics of DOX from the surface of a hard NP carrier. To achieve this, we employed a quantum dot (QD) as a central scaffold which DOX was appended via three different peptidyl linkages (ester, disulfide, hydrazone) that are cleavable in response to various intracellular conditions. Attachment of a cell penetrating peptide (CPP) containing a positively charged polyarginine sequence facilitates endocytosis of the ensemble. Polyhistidine-driven metal affinity coordination was used to self-assemble both peptides to the QD surface, allowing for fine control over both the ratio of peptides attached to the QD as well as DOX dose delivered to cells. Microplate-based Förster resonance energy transfer assays confirmed the successful ratiometric assembly of the conjugates and functionality of the linkages. Cell delivery experiments and cytotoxicity assays were performed to compare the various cleavable linkages to a control peptide where DOX is attached through an amide bond. The role played by various attachment chemistries used in QD-peptide-drug assemblies and their implications for the rationale in design of NPbased constructs for drug delivery is described here.

  6. Calibration of the TIME2 environmental simulation code

    International Nuclear Information System (INIS)

    Wilmot, R.D.; Hiscock, K.; Lloyd, J.

    1991-04-01

    The TARGET finite-difference groundwater modelling code has been used to reconstruct the hydrogeological environment of the area around Killingholme, Humberside, UK. Reconstructions have been made for the present day and for three periods during the past 120,000 years. Permeability development in the Chalk and the stratified nature of the current groundwater system act as boundary conditions for these reconstructions. The results from these reconstructions have been compared with values used by the environmental simulation code TIME2. With optimisation of partition coefficients within the water budget sub-model, values for recharge from TIME2 accord closely with those from this study for temperate and boreal conditions. TIME2 over-estimates recharge during tundra climate states because it does not account for permafrost. (author)

  7. A general purpose code for Monte Carlo simulations

    International Nuclear Information System (INIS)

    Wilcke, W.W.; Rochester Univ., NY

    1984-01-01

    A general-purpose computer code MONTHY has been written to perform Monte Carlo simulations of physical systems. To achieve a high degree of flexibility the code is organized like a general purpose computer, operating on a vector describing the time dependent state of the system under simulation. The instruction set of the 'computer' is defined by the user and is therefore adaptable to the particular problem studied. The organization of MONTHY allows iterative and conditional execution of operations. (orig.)

  8. DLLExternalCode

    Energy Technology Data Exchange (ETDEWEB)

    2014-05-14

    DLLExternalCode is the a general dynamic-link library (DLL) interface for linking GoldSim (www.goldsim.com) with external codes. The overall concept is to use GoldSim as top level modeling software with interfaces to external codes for specific calculations. The DLLExternalCode DLL that performs the linking function is designed to take a list of code inputs from GoldSim, create an input file for the external application, run the external code, and return a list of outputs, read from files created by the external application, back to GoldSim. Instructions for creating the input file, running the external code, and reading the output are contained in an instructions file that is read and interpreted by the DLL.

  9. High efficiency video coding coding tools and specification

    CERN Document Server

    Wien, Mathias

    2015-01-01

    The video coding standard High Efficiency Video Coding (HEVC) targets at improved compression performance for video resolutions of HD and beyond, providing Ultra HD video at similar compressed bit rates as for HD video encoded with the well-established video coding standard H.264 | AVC. Based on known concepts, new coding structures and improved coding tools have been developed and specified in HEVC. The standard is expected to be taken up easily by established industry as well as new endeavors, answering the needs of todays connected and ever-evolving online world. This book presents the High Efficiency Video Coding standard and explains it in a clear and coherent language. It provides a comprehensive and consistently written description, all of a piece. The book targets at both, newbies to video coding as well as experts in the field. While providing sections with introductory text for the beginner, it suits as a well-arranged reference book for the expert. The book provides a comprehensive reference for th...

  10. Outcome of deliveries in healthy but obese women: obesity and delivery outcome

    Directory of Open Access Journals (Sweden)

    Kaplan-Sturk Rebecka

    2013-02-01

    Full Text Available Abstract Background Obesity among fertile women is a global problem. 25% of pregnant Swedish women are overweight at admission to the antenatal clinic and 12% of them are considered as obese. Previous studies have shown an increased risk of delivery complications with an elevated maternal BMI. The aim of this study was to evaluate delivery outcomes in relation to maternal BMI on admission to the antenatal clinic. A healthy group of 787 women with full-term pregnancies and spontaneous onset of labor were included in the study. Delivery outcome was assessed in relation to maternal BMI when attending the antenatal clinic. Results The results indicated that in deliveries where the maternal BMI was >30 a high frequency of abnormal CTG trace during the last 30 minutes of labor was shown. A blood sample for evaluation of risk of fetal hypoxia was performed in only eight percent of these deliveries. A spontaneous vaginal delivery without intervention was noted in 85.7%, and 12% of neonates were delivered with an adverse fetal outcome compared to 2.8% in the group with a maternal BMI Conclusion These results indicate an increased risk at delivery for healthy, but obese women in labor. Furthermore, the delivery management may not always be optimal in these deliveries.

  11. CTCN: Colloid transport code -- nuclear

    International Nuclear Information System (INIS)

    Jain, R.

    1993-01-01

    This report describes the CTCN computer code, designed to solve the equations of transient colloidal transport of radionuclides in porous and fractured media. This Fortran 77 package solves systems of coupled nonlinear differential-algebraic equations with a wide range of boundary conditions. The package uses the Method of Lines technique with a special section which forms finite-difference discretizations in up to four spatial dimensions to automatically convert the system into a set of ordinary differential equations. The CTCN code then solves these equations using a robust, efficient ODE solver. Thus CTCN can be used to solve population balance equations along with the usual transport equations to model colloid transport processes or as a general problem solver to treat up to four-dimensional differential-algebraic systems

  12. Correlation between Kind of Delivery and Posttraumatic Stress ...

    African Journals Online (AJOL)

    Background: Posttraumatic stress disorder (PTSD) is a very common mental condition and a unique anxiety disorder. Aim: The present study tried to examine the correlation between kind of delivery and PTSD. Subjects and Methods: This prospective study evaluated 240 Iranian female residents of Tehran, Iran, during the ...

  13. Timing of delivery after external cephalic version and the risk for cesarean delivery.

    Science.gov (United States)

    Kabiri, Doron; Elram, Tamar; Aboo-Dia, Mushira; Elami-Suzin, Matan; Elchalal, Uriel; Ezra, Yossef

    2011-08-01

    To estimate the association between time of delivery after external cephalic version at term and the risk for cesarean delivery. This retrospective cohort study included all successful external cephalic versions performed in a tertiary center between January 1997 and January 2010. Stepwise logistic regression was used to calculate the odds ratio (OR) for cesarean delivery. We included 483 external cephalic versions in this study, representing 53.1% of all external cephalic version attempts. The incidence of cesarean delivery for 139 women (29%) who gave birth less than 96 hours from external cephalic version was 16.5%; for 344 women (71%) who gave birth greater than 96 hours from external cephalic version, the incidence of cesarean delivery was 7.8% (P = .004). The adjusted OR for cesarean delivery was 2.541 (95% confidence interval 1.36-4.72). When stratified by parity, the risk for cesarean delivery when delivery occurred less than 96 hours after external cephalic version was 2.97 and 2.28 for nulliparous and multiparous women, respectively. Delivery at less than 96 hours after successful external cephalic version was associated with an increased risk for cesarean delivery. III.

  14. Balanced Reed-Solomon codes for all parameters

    KAUST Repository

    Halbawi, Wael; Liu, Zihan; Hassibi, Babak

    2016-01-01

    We construct balanced and sparsest generator matrices for cyclic Reed-Solomon codes with any length n and dimension k. By sparsest, we mean that each row has the least possible number of nonzeros, while balanced means that the number of nonzeros in any two columns differs by at most one. Codes allowing such encoding schemes are useful in distributed settings where computational load-balancing is critical. The problem was first studied by Dau et al. who showed, using probabilistic arguments, that there always exists an MDS code over a sufficiently large field such that its generator matrix is both sparsest and balanced. Motivated by the need for an explicit construction with efficient decoding, the authors of the current paper showed that the generator matrix of a cyclic Reed-Solomon code of length n and dimension k can always be transformed to one that is both sparsest and balanced, when n and k are such that k/n (n-k+1) is an integer. In this paper, we lift this condition and construct balanced and sparsest generator matrices for cyclic Reed-Solomon codes for any set of parameters.

  15. Balanced Reed-Solomon codes for all parameters

    KAUST Repository

    Halbawi, Wael

    2016-10-27

    We construct balanced and sparsest generator matrices for cyclic Reed-Solomon codes with any length n and dimension k. By sparsest, we mean that each row has the least possible number of nonzeros, while balanced means that the number of nonzeros in any two columns differs by at most one. Codes allowing such encoding schemes are useful in distributed settings where computational load-balancing is critical. The problem was first studied by Dau et al. who showed, using probabilistic arguments, that there always exists an MDS code over a sufficiently large field such that its generator matrix is both sparsest and balanced. Motivated by the need for an explicit construction with efficient decoding, the authors of the current paper showed that the generator matrix of a cyclic Reed-Solomon code of length n and dimension k can always be transformed to one that is both sparsest and balanced, when n and k are such that k/n (n-k+1) is an integer. In this paper, we lift this condition and construct balanced and sparsest generator matrices for cyclic Reed-Solomon codes for any set of parameters.

  16. Research Plan: Foam Delivery of Remedial Amendments to Deep Vadose Zone for Metals and Radionuclides Remediation

    International Nuclear Information System (INIS)

    Zhong, Lirong; Hart, Andrea T.; Szecsody, James E.; Zhang, Z.F.; Freedman, Vicky L.; Ankeny, Mark; Hull, Laurence; Oostrom, Martinus; Freshley, Mark D.; Wellman, Dawn M.

    2009-01-01

    Research proposals were submitted to the Scientific and Technical Basis for In Situ Treatment of Metals and Radionuclides Technical Working Group under the US Department of Energy (DOE) Environmental Management Office (specifically, EM-22). After a peer review and selection process, the proposal, 'Foam Delivery of Remedial Amendments to Deep Vadose Zone for Metals and Radionuclides Remediation,' submitted by Pacific Northwest National Laboratory (PNNL) was selected for support by the program. A research plan was requested for this EM funded project. The overall objective of this project is to develop foam delivery technology for the distribution of remedial amendments to deep vadose zone sediments for in situ immobilization of metal and radionuclide contaminants. The focus of this research in FY 2009 is on the physical aspects of the foam delivery approach. Specific objectives are to (1) study the foam quality (i.e. the gas volume fraction in foam) influence on injection pressure, (2) study the sediment air permeability influence on injection pressure, (3) investigate liquid uptake in sediment and determine whether a water front will be formed during foam delivery, (4) test amendment distance (and mass) delivery by foam from the injection point, (5) study the enhanced sweeping over heterogeneous systems (i.e., low K zones) by foam delivery relative to water-based delivery under vadose zone conditions, and (6) numerically simulate foam delivery processes in the vadose zone. Laboratory scale experiments will be conducted at PNNL to study a range of basic physical aspects of the foam propagation in sediments, including foam quality and sediment permeability influence on injection pressure, liquid uptake, and foam sweeping across heterogeneous systems. This study will be augmented with separate studies to be conducted at MSE Technology Applications, Inc. (MSE) to evaluate foam transport and amendment delivery at the intermediate-scale. The results of intermediate

  17. Performance of asynchronous fiber-optic code division multiple access system based on three-dimensional wavelength/time/space codes and its link analysis.

    Science.gov (United States)

    Singh, Jaswinder

    2010-03-10

    A novel family of three-dimensional (3-D) wavelength/time/space codes for asynchronous optical code-division-multiple-access (CDMA) systems with "zero" off-peak autocorrelation and "unity" cross correlation is reported. Antipodal signaling and differential detection is employed in the system. A maximum of [(W x T+1) x W] codes are generated for unity cross correlation, where W and T are the number of wavelengths and time chips used in the code and are prime. The conditions for violation of the cross-correlation constraint are discussed. The expressions for number of generated codes are determined for various code dimensions. It is found that the maximum number of codes are generated for S systems. The codes have a code-set-size to code-size ratio greater than W/S. For instance, with a code size of 2065 (59 x 7 x 5), a total of 12,213 users can be supported, and 130 simultaneous users at a bit-error rate (BER) of 10(-9). An arrayed-waveguide-grating-based reconfigurable encoder/decoder design for 2-D implementation for the 3-D codes is presented so that the need for multiple star couplers and fiber ribbons is eliminated. The hardware requirements of the coders used for various modulation/detection schemes are given. The effect of insertion loss in the coders is shown to be significantly reduced with loss compensation by using an amplifier after encoding. An optical CDMA system for four users is simulated and the results presented show the improvement in performance with the use of loss compensation.

  18. Converter of a continuous code into the Grey code

    International Nuclear Information System (INIS)

    Gonchar, A.I.; TrUbnikov, V.R.

    1979-01-01

    Described is a converter of a continuous code into the Grey code used in a 12-charged precision amplitude-to-digital converter to decrease the digital component of spectrometer differential nonlinearity to +0.7% in the 98% range of the measured band. To construct the converter of a continuous code corresponding to the input signal amplitude into the Grey code used is the regularity in recycling of units and zeroes in each discharge of the Grey code in the case of a continuous change of the number of pulses of a continuous code. The converter is constructed on the elements of 155 series, the frequency of continuous code pulse passing at the converter input is 25 MHz

  19. MODELING OF TARGETED DRUG DELIVERY PART II. MULTIPLE DRUG ADMINISTRATION

    Directory of Open Access Journals (Sweden)

    A. V. Zaborovskiy

    2017-01-01

    Full Text Available In oncology practice, despite significant advances in early cancer detection, surgery, radiotherapy, laser therapy, targeted therapy, etc., chemotherapy is unlikely to lose its relevance in the near future. In this context, the development of new antitumor agents is one of the most important problems of cancer research. In spite of the importance of searching for new compounds with antitumor activity, the possibilities of the “old” agents have not been fully exhausted. Targeted delivery of antitumor agents can give them a “second life”. When developing new targeted drugs and their further introduction into clinical practice, the change in their pharmacodynamics and pharmacokinetics plays a special role. The paper describes a pharmacokinetic model of the targeted drug delivery. The conditions under which it is meaningful to search for a delivery vehicle for the active substance were described. Primary screening of antitumor agents was undertaken to modify them for the targeted delivery based on underlying assumptions of the model.

  20. The METEOR/TRANSURANUS fuel performance code

    International Nuclear Information System (INIS)

    Struzik, C.; Guerin, Y.

    1996-01-01

    The first calculations for the FUMEX exercise were performed using version 1.1 of the METEOR/TRANSURANUS code. Since then, important improvements have been implemented on several models. In its present state, the code describes fuel rod behaviour in standard PWR conditions. Its validity extends to UO 2 and MOX fuels clad in Zircaloy-4. Power transient calculations for UO 2 and Gd doped fuel calculations are possible, but further developments are in progress, and the applications will be fully qualified in version 2.0. A considerable effort is made to replace semi-empirical models with models that have a sounder physical basis. (authors). 14 refs

  1. Modified montmorillonite as vector for gene delivery.

    Science.gov (United States)

    Lin, Feng-Huei; Chen, Chia-Hao; Cheng, Winston T K; Kuo, Tzang-Fu

    2006-06-01

    Currently, gene delivery systems can be divided into two parts: viral or non-viral vectors. In general, viral vectors have a higher efficiency on gene delivery. However, they may sometimes provoke mutagenesis and carcinogenesis once re-activating in human body. Lots of non-viral vectors have been developed that tried to solve the problems happened on viral vectors. Unfortunately, most of non-viral vectors showed relatively lower transfection rate. The aim of this study is to develop a non-viral vector for gene delivery system. Montmorillonite (MMT) is one of clay minerals that consist of hydrated aluminum with Si-O tetrahedrons on the bottom of the layer and Al-O(OH)2 octahedrons on the top. The inter-layer space is about 12 A. The room is not enough to accommodate DNA for gene delivery. In the study, the cationic hexadecyltrimethylammonium (HDTMA) will be intercalated into the interlayer of MMT as a layer expander to expand the layer space for DNA accommodation. The optimal condition for the preparation of DNA-HDTMA-MMT is as follows: 1 mg of 1.5CEC HDTMA-MMT was prepared under pH value of 10.7 and with soaking time for 2 h. The DNA molecules can be protected from nuclease degradation, which can be proven by the electrophoresis analysis. DNA was successfully transfected into the nucleus of human dermal fibroblast and expressed enhanced green fluorescent protein (EGFP) gene with green fluorescence emission. The HDTMA-MMT has a great potential as a vector for gene delivery in the future.

  2. Codes of conduct: An extra suave instrument of EU governance?

    DEFF Research Database (Denmark)

    Borras, Susana

    able to coordinate actors successfully (effectiveness)? and secondly, under what conditions are codes of conduct able to generate democratically legitimate political processes? The paper examines carefully a recent case study, the “Code of Conduct for the Recruitment of Researchers” (CCRR). The code...... establishes a specific set of voluntary norms and principles that shall guide the recruiting process of researchers by European research organizations (universities, public research organizations and firms) in the 33 countries of the single market minded initiative of the European Research Area. A series...

  3. Ultrasound-Mediated Drug/Gene Delivery in Solid Tumor Treatment

    Directory of Open Access Journals (Sweden)

    Yufeng Zhou

    2013-01-01

    Full Text Available Ultrasound is an emerging modality for drug delivery in chemotherapy. This paper reviews this novel technology by first introducing the designs and characteristics of three classes of drug/gene vehicles, microbubble (including nanoemulsion, liposomes, and micelles. In comparison to conventional free drug, the targeted drug-release and delivery through vessel wall and interstitial space to cancerous cells can be activated and enhanced under certain sonication conditions. In the acoustic field, there are several reactions of these drug vehicles, including hyperthermia, bubble cavitation, sonoporation, and sonodynamics, whose physical properties are illustrated for better understanding of this approach. In vitro and in vivo results are summarized, and future directions are discussed. Altogether, ultrasound-mediated drug/gene delivery under imaging guidance provides a promising option in cancer treatment with enhanced agent release and site specificity and reduced toxicity.

  4. NACOM - a code for sodium spray fire analysis

    International Nuclear Information System (INIS)

    Rao, P.M.; Kannan, S.E.

    2002-01-01

    Full text: In liquid metal fast breeder reactors (LMFBR), leakage of sodium can result in a spray fire. Because of higher burning rates in droplet form combustion of sodium in spray fire, thermal consequences are more severe than that in a sodium pool fire. The code NACOM was developed for the analysis of sodium spray fires in LMFBRs facilities. The code uses the validated model for estimating the falling droplet burning rates in pre-ignition and vapour phase combustion stages. It uses a distribution system to generate the droplet groups of different diameters that represent the spray. The code requires about 20 input parameters like sodium leak rates, sodium temperature, initial cell conditions like oxygen concentration, temperature and dimensions. NACOM is a validated code based on experiments with sodium inventory up to 650 kg in 0 to 21 % O 2 atmospheres. The paper brings out the salient features of the code along with the sensitivity analysis of the main input parameters like spray volume mean diameter, oxygen concentration etc. based on the results obtained. The limitations of the code and the confidence margins applicable to results obtained are also brought out

  5. Strength evaluation code STEP for brittle materials

    International Nuclear Information System (INIS)

    Ishihara, Masahiro; Futakawa, Masatoshi.

    1997-12-01

    In a structural design using brittle materials such as graphite and/or ceramics it is necessary to evaluate the strength of component under complex stress condition. The strength of ceramic materials is said to be influenced by the stress distribution. However, in the structural design criteria simplified stress limits had been adopted without taking account of the strength change with the stress distribution. It is, therefore, important to evaluate the strength of component on the basis of the fracture model for brittle material. Consequently, the strength evaluation program, STEP, on a brittle fracture of ceramic materials based on the competing risk theory had been developed. Two different brittle fracture modes, a surface layer fracture mode dominated by surface flaws and an internal fracture mode by internal flaws, are treated in the STEP code in order to evaluate the strength of brittle fracture. The STEP code uses stress calculation results including complex shape of structures analyzed by the generalized FEM stress analysis code, ABAQUS, so as to be possible to evaluate the strength of brittle fracture for the structures having complicate shapes. This code is, therefore, useful to evaluate the structural integrity of arbitrary shapes of components such as core graphite components in the HTTR, heat exchanger components made of ceramics materials etc. This paper describes the basic equations applying to the STEP code, code system with a combination of the STEP and the ABAQUS codes and the result of the verification analysis. (author)

  6. A method for assessing fidelity of delivery of telephone behavioral support for smoking cessation.

    Science.gov (United States)

    Lorencatto, Fabiana; West, Robert; Bruguera, Carla; Michie, Susan

    2014-06-01

    Behavioral support for smoking cessation is delivered through different modalities, often guided by treatment manuals. Recently developed methods for assessing fidelity of delivery have shown that face-to-face behavioral support is often not delivered as specified in the service treatment manual. This study aimed to extend this method to evaluate fidelity of telephone-delivered behavioral support. A treatment manual and transcripts of 75 audio-recorded behavioral support sessions were obtained from the United Kingdom's national Quitline service and coded into component behavior change techniques (BCTs) using a taxonomy of 45 smoking cessation BCTs. Interrater reliability was assessed using percentage agreement. Fidelity was assessed by comparing the number of BCTs identified in the manual with those delivered in telephone sessions by 4 counselors. Fidelity was assessed according to session type, duration, counselor, and BCT. Differences between self-reported and actual BCT use were examined. Average coding reliability was high (81%). On average, 41.8% of manual-specified BCTs were delivered per session (SD = 16.2), with fidelity varying by counselor from 32% to 49%. Fidelity was highest in pre-quit sessions (46%) and for BCT "give options for additional support" (95%). Fidelity was lowest for quit-day sessions (35%) and BCT "set graded tasks" (0%). Session duration was positively correlated with fidelity (r = .585; p reliably coded in terms of BCTs. This can be used to assess fidelity to treatment manuals and to in turn identify training needs. The observed low fidelity underlines the need to establish routine procedures for monitoring delivery of behavioral support. PsycINFO Database Record (c) 2014 APA, all rights reserved.

  7. Survey on Monitoring and Quality Controlling of the Mobile Biosignal Delivery.

    Science.gov (United States)

    Pawar, Pravin A; Edla, Damodar R; Edoh, Thierry; Shinde, Vijay; van Beijnum, Bert-Jan

    2017-10-31

    A Mobile Patient Monitoring System (MPMS) acquires patient's biosignals and transmits them using wireless network connection to the decision-making module or healthcare professional for the assessment of patient's condition. A variety of wireless network technologies such as wireless personal area networks (e.g., Bluetooth), mobile ad-hoc networks (MANET), and infrastructure-based networks (e.g., WLAN and cellular networks) are in practice for biosignals delivery. The wireless network quality-of-service (QoS) requirements of biosignals delivery are mainly specified in terms of required bandwidth, acceptable delay, and tolerable error rate. An important research challenge in the MPMS is how to satisfy QoS requirements of biosignals delivery in the environment characterized by patient mobility, deployment of multiple wireless network technologies, and variable QoS characteristics of the wireless networks. QoS requirements are mainly application specific, while available QoS is largely dependent on QoS provided by wireless network in use. QoS provisioning refers to providing support for improving QoS experience of networked applications. In resource poor conditions, application adaptation may also be required to make maximum use of available wireless network QoS. This survey paper presents a survey of recent developments in the area of QoS provisioning for MPMS. In particular, our contributions are as follows: (1) overview of wireless networks and network QoS requirements of biosignals delivery; (2) survey of wireless networks' QoS performance evaluation for the transmission of biosignals; and (3) survey of QoS provisioning mechanisms for biosignals delivery in MPMS. We also propose integrating end-to-end QoS monitoring and QoS provisioning strategies in a mobile patient monitoring system infrastructure to support optimal delivery of biosignals to the healthcare professionals.

  8. What we have learned about scheduling elective repeat cesarean delivery at term.

    Science.gov (United States)

    Tita, Alan T N

    2016-08-01

    The optimal timing of delivery in the setting of various clinical conditions and scenarios remains one of the most common questions for obstetric providers. Over the past 5-10 years, the optimal timing of delivery at term, particularly for elective repeat cesareans, has been the subject of considerable investigation and discussion. There is an increasing consensus that when women opt for an elective repeat cesarean delivery, it should be performed at term rather than preterm. The recent redefinition of the "term" period into early term (37-38 weeks), full-term (39-40 weeks), late term (41 weeks), and post term designations (≥42 weeks) underscores observed heterogeneity in outcomes following delivery at term. The American College of Obstetricians and Gynecologists currently recommends that elective repeat cesarean delivery be performed at full-term. Herein, the available data to support this recommendation regarding timing of elective repeat cesarean delivery are reviewed, including contributions from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Maternal-Fetal Medicine Units (MFMU) Network. Copyright © 2016. Published by Elsevier Inc.

  9. Entanglement-assisted quantum MDS codes constructed from negacyclic codes

    Science.gov (United States)

    Chen, Jianzhang; Huang, Yuanyuan; Feng, Chunhui; Chen, Riqing

    2017-12-01

    Recently, entanglement-assisted quantum codes have been constructed from cyclic codes by some scholars. However, how to determine the number of shared pairs required to construct entanglement-assisted quantum codes is not an easy work. In this paper, we propose a decomposition of the defining set of negacyclic codes. Based on this method, four families of entanglement-assisted quantum codes constructed in this paper satisfy the entanglement-assisted quantum Singleton bound, where the minimum distance satisfies q+1 ≤ d≤ n+2/2. Furthermore, we construct two families of entanglement-assisted quantum codes with maximal entanglement.

  10. Relating quantum discord with the quantum dense coding capacity

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Xin; Qiu, Liang, E-mail: lqiu@cumt.edu.cn; Li, Song; Zhang, Chi [China University of Mining and Technology, School of Sciences (China); Ye, Bin [China University of Mining and Technology, School of Information and Electrical Engineering (China)

    2015-01-15

    We establish the relations between quantum discord and the quantum dense coding capacity in (n + 1)-particle quantum states. A necessary condition for the vanishing discord monogamy score is given. We also find that the loss of quantum dense coding capacity due to decoherence is bounded below by the sum of quantum discord. When these results are restricted to three-particle quantum states, some complementarity relations are obtained.

  11. Relating quantum discord with the quantum dense coding capacity

    International Nuclear Information System (INIS)

    Wang, Xin; Qiu, Liang; Li, Song; Zhang, Chi; Ye, Bin

    2015-01-01

    We establish the relations between quantum discord and the quantum dense coding capacity in (n + 1)-particle quantum states. A necessary condition for the vanishing discord monogamy score is given. We also find that the loss of quantum dense coding capacity due to decoherence is bounded below by the sum of quantum discord. When these results are restricted to three-particle quantum states, some complementarity relations are obtained

  12. Computational and experimental model of transdermal iontophorethic drug delivery system.

    Science.gov (United States)

    Filipovic, Nenad; Saveljic, Igor; Rac, Vladislav; Graells, Beatriz Olalde; Bijelic, Goran

    2017-11-30

    The concept of iontophoresis is often applied to increase the transdermal transport of drugs and other bioactive agents into the skin or other tissues. It is a non-invasive drug delivery method which involves electromigration and electroosmosis in addition to diffusion and is shown to be a viable alternative to conventional administration routs such as oral, hypodermic and intravenous injection. In this study we investigated, experimentally and numerically, in vitro drug delivery of dexamethasone sodium phosphate to porcine skin. Different current densities, delivery durations and drug loads were investigated experimentally and introduced as boundary conditions for numerical simulations. Nernst-Planck equation was used for calculation of active substance flux through equivalent model of homogeneous hydrogel and skin layers. The obtained numerical results were in good agreement with experimental observations. A comprehensive in-silico platform, which includes appropriate numerical tools for fitting, could contribute to iontophoretic drug-delivery devices design and correct dosage and drug clearance profiles as well as to perform much faster in-silico experiments to better determine parameters and performance criteria of iontophoretic drug delivery. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. Neonatal outcomes in fetuses with cardiac anomalies and the impact of delivery route.

    Science.gov (United States)

    Parikh, Laura I; Grantz, Katherine L; Iqbal, Sara N; Huang, Chun-Chih; Landy, Helain J; Fries, Melissa H; Reddy, Uma M

    2017-10-01

    Congenital fetal cardiac anomalies compromise the most common group of fetal structural anomalies. Several previous reports analyzed all types of fetal cardiac anomalies together without individualized neonatal morbidity outcomes based on cardiac defect. Mode of delivery in cases of fetal cardiac anomalies varies greatly as optimal mode of delivery in these complex cases is unknown. We sought to determine rates of neonatal outcomes for fetal cardiac anomalies and examine the role of attempted route of delivery on neonatal morbidity. Gravidas with fetal cardiac anomalies and delivery >34 weeks, excluding stillbirths and aneuploidies (n = 2166 neonates, n = 2701 cardiac anomalies), were analyzed from the Consortium on Safe Labor, a retrospective cohort study of electronic medical records. Cardiac anomalies were determined using International Classification of Diseases, Ninth Revision codes and organized based on morphology. Neonates were assigned to each cardiac anomaly classification based on the most severe cardiac defect present. Neonatal outcomes were determined for each fetal cardiac anomaly. Composite neonatal morbidity (serious respiratory morbidity, sepsis, birth trauma, hypoxic ischemic encephalopathy, and neonatal death) was compared between attempted vaginal delivery and planned cesarean delivery for prenatal and postnatal diagnosis. We used multivariate logistic regression to calculate adjusted odds ratio for composite neonatal morbidity controlling for race, parity, body mass index, insurance, gestational age, maternal disease, single or multiple anomalies, and maternal drug use. Most cardiac anomalies were diagnosed postnatally except hypoplastic left heart syndrome, which had a higher prenatal than postnatal detection rate. Neonatal death occurred in 8.4% of 107 neonates with conotruncal defects. Serious respiratory morbidity occurred in 54.2% of 83 neonates with left ventricular outflow tract defects. Overall, 76.3% of pregnancies with fetal

  14. System transient analysis code development for low pressure and low power

    International Nuclear Information System (INIS)

    Kim, Hee Cheol

    1998-02-01

    A real time reactor system analysis code, ARTIST, based on drift flux model has been developed to investigate the transient system behavior under low pressure, low flow and low power conditions with noncondensable gas present in the system. The governing equations of the ARTIST code consist of three mass continuity equations (steam, liquid and noncondensable), two energy equations (gas and mixture) and one momentum equation (mixture) constituted with the drift flux model. The capability of ARTIST in predicting two-phase flow void distribution in the system has been validated against experimental data. The results of the ARTIST axial void distribution at low pressure and low flow, are far better than the results of both the homogeneous model of TASS code and the two-fluid model of RELAP5/MOD3 code. Also, RELAP5/MOD3 calculation shows the large amplitude of void fraction oscillations at low pressure. These results imply that interfacial momentum transfer terms in the two-fluid model formulation should be carefully constituted, especially for the low pressure condition due to the big density differences between steam and water. Thermal-hydraulic state solution scheme is developed when noncondensable gas exists. Numerical consistency and convergence of obtaining equilibrium state is tested with the ideal problems for various situations including very low partial pressure conditions. Calculated thermal-hydraulic state for each test shows consistent and expected behaviour. A new multi-layer back propagation network algorithm for calculating the departure from nucleate boiling ratio (DNBR) is developed and adopted in ARTIST code in order to have real-time DNBR evaluation by eliminating the tandem procedure of the transient DNBR calculation. The algorithm trained by different patterns generated by latin hypercube sampling method on the performance space is tested for the randomly sampled untrained data and the transient DNBR data. The uncertainty of the algorithm is

  15. Error-correction coding

    Science.gov (United States)

    Hinds, Erold W. (Principal Investigator)

    1996-01-01

    This report describes the progress made towards the completion of a specific task on error-correcting coding. The proposed research consisted of investigating the use of modulation block codes as the inner code of a concatenated coding system in order to improve the overall space link communications performance. The study proposed to identify and analyze candidate codes that will complement the performance of the overall coding system which uses the interleaved RS (255,223) code as the outer code.

  16. Evaporation over sump surface in containment studies: code validation on TOSQAN tests

    International Nuclear Information System (INIS)

    Malet, J.; Gelain, T.; Degrees du Lou, O.; Daru, V.

    2011-01-01

    During the course of a severe accident in a Nuclear Power Plant, water can be collected in the sump containment through steam condensation on walls and spray systems activation. The objective of this paper is to present code validation on evaporative sump tests performed on the TOSQAN facility. The ASTEC-CPA code is used as a lumped-parameter code and specific user-defined-functions are developed for the TONUS-CFD code. The tests are air-steam tests, as well as tests with other non-condensable gases (He, CO 2 and SF 6 ) under steady and transient conditions. The results show a good agreement between codes and experiments, indicating a good behaviour of the sump models in both codes. (author)

  17. Environmental conditions using thermal-hydraulics computer code GOTHIC for beyond design basis external events

    International Nuclear Information System (INIS)

    Pleskunas, R.J.

    2015-01-01

    In response to the Fukushima Dai-ichi beyond design basis accident in March 2011, the Nuclear Regulatory Commission (NRC) issued Order EA-12-049, 'Issuance of Order to Modify Licenses with Regard to Requirements for Mitigation Strategies Beyond-Design-Basis-External-Events'. To outline the process to be used by individual licensees to define and implement site-specific diverse and flexible mitigation strategies (FLEX) that reduce the risks associated with beyond design basis conditions, Nuclear Energy Institute document NEI 12-06, 'Diverse and Flexible Coping Strategies (FLEX) Implementation Guide', was issued. A beyond design basis external event (BDBEE) is postulated to cause an Extended Loss of AC Power (ELAP), which will result in a loss of ventilation which has the potential to impact room habitability and equipment operability. During the ELAP, portable FLEX equipment will be used to achieve and maintain safe shutdown, and only a minimal set of instruments and controls will be available. Given these circumstances, analysis is required to determine the environmental conditions in several vital areas of the Nuclear Power Plant. The BDBEE mitigating strategies require certain room environments to be maintained such that they can support the occupancy of personnel and the functionality of equipment located therein, which is required to support the strategies associated with compliance to NRC Order EA-12-049. Three thermal-hydraulic analyses of vital areas during an extended loss of AC power using the GOTHIC computer code will be presented: 1) Safety-related pump and instrument room transient analysis; 2) Control Room transient analysis; and 3) Auxiliary/Control Building transient analysis. GOTHIC (Generation of Thermal-Hydraulic Information for Containment) is a general purpose thermal-hydraulics software package for the analysis of nuclear power plant containments, confinement buildings, and system components. It is a volume/path/heat sink

  18. Effect of severity of illness on cesarean delivery rates in Washington State.

    Science.gov (United States)

    Hitti, Jane; Walker, Suzan; Benedetti, Thomas J

    2017-10-01

    Hospitals and providers are increasingly held accountable for their cesarean delivery rates. In the perinatal quality improvement arena, there is vigorous debate about whether all hospitals can be held to the same benchmark for an acceptable cesarean rate regardless of patient acuity. However, the causes of variation in hospital cesarean delivery rates are not well understood. We sought to evaluate the association and temporal trends between severity of illness at admission and the primary term singleton vertex cesarean delivery rate among hospitals in Washington State. We hypothesized that hospitals with higher patient acuity would have higher cesarean delivery rates and that this pattern would persist over time. In this cross-sectional analysis, we analyzed aggregate hospital-level data for all nonmilitary hospitals in Washington State with ≥100 deliveries/y during federal fiscal years 2010 through 2014 (287,031 deliveries). Data were obtained from the Washington State Comprehensive Hospital Abstract Reporting System, which includes inpatient demographic, diagnosis, procedure, and discharge information derived from hospital billing systems. Age, admission diagnoses and procedure codes were converted to patient-level admission severity-of-illness scores using the All Patient Refined Diagnosis Related Groups classification system. This system is widely used throughout the United States to adjust hospital data for severity of illness. Mean admission hospital-level severity-of-illness scores were calculated for each fiscal year among the term singleton vertex population with no history of cesarean delivery. We used linear regression to evaluate the association between hospital admission severity of illness and the primary term singleton vertex cesarean delivery rate, calculated Pearson correlation coefficients, and compared regression line slopes and 95% confidence intervals for each fiscal year. Hospitals were diverse with respect to delivery volume, level of care

  19. Turbo-Gallager Codes: The Emergence of an Intelligent Coding ...

    African Journals Online (AJOL)

    Today, both turbo codes and low-density parity-check codes are largely superior to other code families and are being used in an increasing number of modern communication systems including 3G standards, satellite and deep space communications. However, the two codes have certain distinctive characteristics that ...

  20. Large-eddy simulation of stratified atmospheric flows with the CFD code Code-Saturne

    International Nuclear Information System (INIS)

    Dall'Ozzo, Cedric

    2013-01-01

    Large-eddy simulation (LES) of the physical processes in the atmospheric boundary layer (ABL) remains a complex subject. LES models have difficulties to capture the evolution of the turbulence in different conditions of stratification. Consequently, LES of the whole diurnal cycle of the ABL including convective situations in daytime and stable situations in the nighttime is seldom documented. The simulation of the stable atmospheric boundary layer which is characterized by small eddies and by weak and sporadic turbulence is especially difficult. Therefore The LES ability to well reproduce real meteorological conditions, particularly in stable situations, is studied with the CFD code developed by EDF R and D, Code-Saturne. The first study consist in validate LES on a quasi-steady state convective case with homogeneous terrain. The influence of the sub-grid-scale models (Smagorinsky model, Germano-Lilly model, Wong-Lilly model and Wall-Adapting Local Eddy-viscosity model) and the sensitivity to the parametrization method on the mean fields, flux and variances are discussed. In a second study, the diurnal cycle of the ABL during Wangara experiment is simulated. The deviation from the measurement is weak during the day, so this work is focused on the difficulties met during the night to simulate the stable atmospheric boundary layer. The impact of the different sub-grid-scale models and the sensitivity to the Smagorinsky constant are been analysed. By coupling radiative forcing with LES, the consequences of infra-red and solar radiation on the nocturnal low level jet and on thermal gradient, close to the surface, are exposed. More, enhancement of the domain resolution to the turbulence intensity and the strong atmospheric stability during the Wangara experiment are analysed. Finally, a study of the numerical oscillations inherent to Code-Saturne is realized in order to decrease their effects. (author) [fr

  1. [Towards a new Tunisian Medical Code of Deontology].

    Science.gov (United States)

    Aissaoui, Abir; Haj Salem, Nidhal; Chadly, Ali

    2010-06-01

    The Medical Code of Deontology is a legal text including the physician's duties towards his patients, colleagues, auxiliaries and the community. Considering the scientific, legal and social changes, the deontology code should be revised periodically. The first Tunisian Medical Code of Deontology (TMCD) was promulgated in 1973 and abrogated in 1993 by the new Code. This version has never been reviewed and does not seem to fit the current conditions of medical practice. The TMCD does not contain texts referring to information given to the patient, pain control, palliative care and management of the end of life as well as protection of medical data. Furthermore, the TMCD does not include rules related to tissues and organs transplantation and medical assisted human reproduction in accordance with Tunisian legal texts. We aim in this paper at analyzing the insufficiencies of the TMCD and suggesting modifications in order to update it.

  2. TASS code topical report. V.1 TASS code technical manual

    International Nuclear Information System (INIS)

    Sim, Suk K.; Chang, W. P.; Kim, K. D.; Kim, H. C.; Yoon, H. Y.

    1997-02-01

    TASS 1.0 code has been developed at KAERI for the initial and reload non-LOCA safety analysis for the operating PWRs as well as the PWRs under construction in Korea. TASS code will replace various vendor's non-LOCA safety analysis codes currently used for the Westinghouse and ABB-CE type PWRs in Korea. This can be achieved through TASS code input modifications specific to each reactor type. The TASS code can be run interactively through the keyboard operation. A simimodular configuration used in developing the TASS code enables the user easily implement new models. TASS code has been programmed using FORTRAN77 which makes it easy to install and port for different computer environments. The TASS code can be utilized for the steady state simulation as well as the non-LOCA transient simulations such as power excursions, reactor coolant pump trips, load rejections, loss of feedwater, steam line breaks, steam generator tube ruptures, rod withdrawal and drop, and anticipated transients without scram (ATWS). The malfunctions of the control systems, components, operator actions and the transients caused by the malfunctions can be easily simulated using the TASS code. This technical report describes the TASS 1.0 code models including reactor thermal hydraulic, reactor core and control models. This TASS code models including reactor thermal hydraulic, reactor core and control models. This TASS code technical manual has been prepared as a part of the TASS code manual which includes TASS code user's manual and TASS code validation report, and will be submitted to the regulatory body as a TASS code topical report for a licensing non-LOCA safety analysis for the Westinghouse and ABB-CE type PWRs operating and under construction in Korea. (author). 42 refs., 29 tabs., 32 figs

  3. Improved overall delivery documentation following implementation of a standardized shoulder dystocia delivery form

    Science.gov (United States)

    Moragianni, Vasiliki A.; Hacker, Michele R.; Craparo, Frank J.

    2013-01-01

    Objective Our objective was to evaluate whether using a standardized shoulder dystocia delivery form improved documentation. A standardized delivery form was added to our institution’s obstetrical record in August 2003. Methods A retrospective cohort study was conducted comparing 100 vaginal deliveries complicated by shoulder dystocia before, and 81 after implementation of the standardized delivery form. The two groups were compared in terms of obstetric characteristics, neonatal outcomes and documentation components. Results Charts that included the standardized delivery form were more likely to contain documentation of estimated fetal weight (82.7% vs. 39.0% without the form, Pdystocia, and second stage duration. Conclusions Inclusion of a standardized form in the delivery record improves the rate of documentation of both shoulder dystocia-specific and general delivery components. PMID:22017330

  4. Independent verification and validation testing of the FLASH computer code, Versiion 3.0

    International Nuclear Information System (INIS)

    Martian, P.; Chung, J.N.

    1992-06-01

    Independent testing of the FLASH computer code, Version 3.0, was conducted to determine if the code is ready for use in hydrological and environmental studies at various Department of Energy sites. This report describes the technical basis, approach, and results of this testing. Verification tests, and validation tests, were used to determine the operational status of the FLASH computer code. These tests were specifically designed to test: correctness of the FORTRAN coding, computational accuracy, and suitability to simulating actual hydrologic conditions. This testing was performed using a structured evaluation protocol which consisted of: blind testing, independent applications, and graduated difficulty of test cases. Both quantitative and qualitative testing was performed through evaluating relative root mean square values and graphical comparisons of the numerical, analytical, and experimental data. Four verification test were used to check the computational accuracy and correctness of the FORTRAN coding, and three validation tests were used to check the suitability to simulating actual conditions. These tests cases ranged in complexity from simple 1-D saturated flow to 2-D variably saturated problems. The verification tests showed excellent quantitative agreement between the FLASH results and analytical solutions. The validation tests showed good qualitative agreement with the experimental data. Based on the results of this testing, it was concluded that the FLASH code is a versatile and powerful two-dimensional analysis tool for fluid flow. In conclusion, all aspects of the code that were tested, except for the unit gradient bottom boundary condition, were found to be fully operational and ready for use in hydrological and environmental studies

  5. The development of the fuel rod transient performance analysis code FTPAC

    International Nuclear Information System (INIS)

    Han Zhijie; Ji Songtao

    2014-01-01

    Fuel rod behavior, especially the integrity of cladding, played an important role in fuel safety research during reactor transient and hypothetical accidents conditions. In order to study fuel rod performance under transient accidents, FTPAC (Fuel Transient Performance Analysis Code) has been developed for simulating light water reactor fuel rod transient behavior when power or coolant boundary conditions are rapidly changing. It is composed of temperature, mechanical deformation, cladding oxidation and gas pressure model. The assessment was performed by comparing FTPAC code analysis result to experiments data and FRAPTRAN code calculations. Comparison shows that, the FTPAC gives reasonable agreement in temperature, deformation and gas pressure prediction. And the application of slip coefficient is more suitable for simulating the sliding between pellet and cladding when the gap is closed. (authors)

  6. Use of GOTHIC Code for Assessment of Equipment Environmental Qualification

    International Nuclear Information System (INIS)

    Cavlina, N.; Feretic, D.; Grgic, D.; Spalj, S.; Spiler, J.

    1996-01-01

    Environmental qualification (EQ) of equipment important to safety in nuclear power plants ensures its capability to perform designated safety function on demand under postulated service conditions, including harsh accident environment (e. g. LOCA, HELB). The computer code GOTHIC was used to calculate pressure and temperature profiles inside NPP Krsko containment during limiting LOCA and MSLB accidents. The results of the new best-estimate containment code are compared to the older CONTEMPT code using the same input data and assumptions. The predictions obtained by both codes are very similar. As a result of the calculation the envelopes of the LOCA and MSLB pressures and temperatures, as used in FSAR/USAR Chapter 6, can be used in EQ project. (author)

  7. Methodology for Evaluating Cost-effectiveness of Commercial Energy Code Changes

    Energy Technology Data Exchange (ETDEWEB)

    Hart, Philip R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Liu, Bing [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2015-01-31

    This document lays out the U.S. Department of Energy’s (DOE’s) method for evaluating the cost-effectiveness of energy code proposals and editions. The evaluation is applied to provisions or editions of the American Society of Heating, Refrigerating and Air-Conditioning Engineers (ASHRAE) Standard 90.1 and the International Energy Conservation Code (IECC). The method follows standard life-cycle cost (LCC) economic analysis procedures. Cost-effectiveness evaluation requires three steps: 1) evaluating the energy and energy cost savings of code changes, 2) evaluating the incremental and replacement costs related to the changes, and 3) determining the cost-effectiveness of energy code changes based on those costs and savings over time.

  8. Features of RAPTA-SFD code modelling of chemical interactions of basic materials of the WWER active zone in accident conditions with severe fuel damage

    International Nuclear Information System (INIS)

    Bibilashvili, Yu.K.; Sokolov, N.B.; Salatov, A.V.; Nechaeva, O.A.; Andreyeva-Andrievskaya, L.N.; Vlasov, F.Yu.

    1996-01-01

    A brief description of RAPTA-SFD code intended for computer simulations of WWER-type fuel elements (simulator or absorber element) in conditions of accident with severe damage of fuel. Presented are models of chemical interactions of basic materials of the active zone, emphasized are special feature of their application in carrying out of the CORA-W2 experiment within the framework of International Standard Problem ISP-36. Results obtained confirm expediency of phenomenological models application. (author). 6 refs, 7 figs, 1 tab

  9. Decoding of concatenated codes with interleaved outer codes

    DEFF Research Database (Denmark)

    Justesen, Jørn; Høholdt, Tom; Thommesen, Christian

    2004-01-01

    Recently Bleichenbacher et al. proposed a decoding algorithm for interleaved (N, K) Reed-Solomon codes, which allows close to N-K errors to be corrected in many cases. We discuss the application of this decoding algorithm to concatenated codes.......Recently Bleichenbacher et al. proposed a decoding algorithm for interleaved (N, K) Reed-Solomon codes, which allows close to N-K errors to be corrected in many cases. We discuss the application of this decoding algorithm to concatenated codes....

  10. Adverse obstetric outcomes during delivery hospitalizations complicated by suicidal behavior among US pregnant women.

    Science.gov (United States)

    Zhong, Qiu-Yue; Gelaye, Bizu; Smoller, Jordan W; Avillach, Paul; Cai, Tianxi; Williams, Michelle A

    2018-01-01

    The effects of suicidal behavior on obstetric outcomes remain dangerously unquantified. We sought to report on the risk of adverse obstetric outcomes for US women with suicidal behavior at the time of delivery. We performed a cross-sectional analysis of delivery hospitalizations from 2007-2012 National (Nationwide) Inpatient Sample. From the same hospitalization record, International Classification of Diseases codes were used to identify suicidal behavior and adverse obstetric outcomes. Adjusted odds ratios (aOR) and 95% confidence intervals (CI) were obtained using logistic regression. Of the 23,507,597 delivery hospitalizations, 2,180 were complicated by suicidal behavior. Women with suicidal behavior were at a heightened risk for outcomes including antepartum hemorrhage (aOR = 2.34; 95% CI: 1.47-3.74), placental abruption (aOR = 2.07; 95% CI: 1.17-3.66), postpartum hemorrhage (aOR = 2.33; 95% CI: 1.61-3.37), premature delivery (aOR = 3.08; 95% CI: 2.43-3.90), stillbirth (aOR = 10.73; 95% CI: 7.41-15.56), poor fetal growth (aOR = 1.70; 95% CI: 1.10-2.62), and fetal anomalies (aOR = 3.72; 95% CI: 2.57-5.40). No significant association was observed for maternal suicidal behavior with cesarean delivery, induction of labor, premature rupture of membranes, excessive fetal growth, and fetal distress. The mean length of stay was longer for women with suicidal behavior. During delivery hospitalization, women with suicidal behavior are at increased risk for many adverse obstetric outcomes, highlighting the importance of screening for and providing appropriate clinical care for women with suicidal behavior during pregnancy.

  11. original article predictors of safe delivery service utilization in arsi

    African Journals Online (AJOL)

    Abrham

    There is limited information on the mothers' use of skilled delivery services in the ... to conditions related to pregnancy and child birth. 99% of .... having favourable attitude towards utilization of ... two injections of Tetanus Toxoid vaccine during.

  12. Fast Coding Unit Encoding Mechanism for Low Complexity Video Coding

    OpenAIRE

    Gao, Yuan; Liu, Pengyu; Wu, Yueying; Jia, Kebin; Gao, Guandong

    2016-01-01

    In high efficiency video coding (HEVC), coding tree contributes to excellent compression performance. However, coding tree brings extremely high computational complexity. Innovative works for improving coding tree to further reduce encoding time are stated in this paper. A novel low complexity coding tree mechanism is proposed for HEVC fast coding unit (CU) encoding. Firstly, this paper makes an in-depth study of the relationship among CU distribution, quantization parameter (QP) and content ...

  13. Development of a Performance Analysis Code for the Off-design conditions of a S-CO2 Brayton Cycle Energy Conversion System

    International Nuclear Information System (INIS)

    Yoo, Yong-Hwan; Cha, Jae-Eun; Lee, Tae-Ho; Eoh, Jae-Hyuk; Kim, Seong-O

    2008-01-01

    For the development of a supercritical carbon dioxide (S-CO2) Brayton cycle energy conversion system coupled to KALIMER-600, a thermal balance has been established on 100% power operating conditions including all the reactor system models such as a primary heat transport system (PHTS), an intermediate heat transport system (IHTS), and an energy conversion system. The S-CO2 Brayton cycle energy conversion system consists of a sodium-CO2 heat exchanger (Hx), turbine, high temperature recuperate (HTR), low temperature recuperate (LTR), precooler, compressor no.1, and compressor no.2. Two compressors were employed to avoid a sharp change of the physical properties near their critical point with a corresponding pressure. The component locations and their operating conditions are illustrated. Energy balance of the power conversion system in KALIMER-600 was designed with the full power condition of each component. Therefore, to predict the off-design conditions and to evaluate each component, an off-design performance analysis code should be accomplished. An off-design performance analysis could be classified into overall system control logic and local system control logic. The former means that mass flow rate and power are controlled by valves, and the latter implies that a bypass or inventory control is an admitted system balance. The ultimate goal of this study is development of the overall system control logic

  14. Nanostructures for delivery of natural antimicrobials in food.

    Science.gov (United States)

    Lopes, Nathalie Almeida; Brandelli, Adriano

    2017-04-10

    Natural antimicrobial compounds are a topic of utmost interest in food science due to the increased demand for safe and high-quality foods with minimal processing. The use of nanostructures is an interesting alternative to protect and delivery antimicrobials in food, also providing controlled release of natural compounds such as bacteriocins and antimicrobial proteins, and also for delivery of plant derived antimicrobials. A diversity of nanostructures are capable of trapping natural antimicrobials maintaining the stability of substances that are frequently sensitive to food processing and storage conditions. This article provides an overview on natural antimicrobials incorporated in nanostructures, showing an effective antimicrobial activity on a diversity of food spoilage and pathogenic microorganisms.

  15. Fuel behaviour calculations with version 2.0 of the code FUROM

    International Nuclear Information System (INIS)

    Kulacsy, K.

    2011-01-01

    The fuel modelling code FUROM (FUel ROd Model), suitable for calculating the normal operation condition behaviour of PWR and WWER fuels, has been developed at AEKI for several years. In 2010 the new version of the code, FUROM-2.0 was released. Calculations performed with this version and results are presented. (author)

  16. Codes Over Hyperfields

    Directory of Open Access Journals (Sweden)

    Atamewoue Surdive

    2017-12-01

    Full Text Available In this paper, we define linear codes and cyclic codes over a finite Krasner hyperfield and we characterize these codes by their generator matrices and parity check matrices. We also demonstrate that codes over finite Krasner hyperfields are more interesting for code theory than codes over classical finite fields.

  17. PCCE-A Predictive Code for Calorimetric Estimates in actively cooled components affected by pulsed power loads

    International Nuclear Information System (INIS)

    Agostinetti, P.; Palma, M. Dalla; Fantini, F.; Fellin, F.; Pasqualotto, R.

    2011-01-01

    The analytical interpretative models for calorimetric measurements currently available in the literature can consider close systems in steady-state and transient conditions, or open systems but only in steady-state conditions. The PCCE code (Predictive Code for Calorimetric Estimations), here presented, introduces some novelties. In fact, it can simulate with an analytical approach both the heated component and the cooling circuit, evaluating the heat fluxes due to conductive and convective processes both in steady-state and transient conditions. The main goal of this code is to model heating and cooling processes in actively cooled components of fusion experiments affected by high pulsed power loads, that are not easily analyzed with purely numerical approaches (like Finite Element Method or Computational Fluid Dynamics). A dedicated mathematical formulation, based on concentrated parameters, has been developed and is here described in detail. After a comparison and benchmark with the ANSYS commercial code, the PCCE code is applied to predict the calorimetric parameters in simple scenarios of the SPIDER experiment.

  18. Amino acid codes in mitochondria as possible clues to primitive codes

    Science.gov (United States)

    Jukes, T. H.

    1981-01-01

    Differences between mitochondrial codes and the universal code indicate that an evolutionary simplification has taken place, rather than a return to a more primitive code. However, these differences make it evident that the universal code is not the only code possible, and therefore earlier codes may have differed markedly from the previous code. The present universal code is probably a 'frozen accident.' The change in CUN codons from leucine to threonine (Neurospora vs. yeast mitochondria) indicates that neutral or near-neutral changes occurred in the corresponding proteins when this code change took place, caused presumably by a mutation in a tRNA gene.

  19. Preserving Envelope Efficiency in Performance Based Code Compliance

    Energy Technology Data Exchange (ETDEWEB)

    Thornton, Brian A. [Thornton Energy Consulting (United States); Sullivan, Greg P. [Efficiency Solutions (United States); Rosenberg, Michael I. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Baechler, Michael C. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2015-06-20

    The City of Seattle 2012 Energy Code (Seattle 2014), one of the most progressive in the country, is under revision for its 2015 edition. Additionally, city personnel participate in the development of the next generation of the Washington State Energy Code and the International Energy Code. Seattle has pledged carbon neutrality by 2050 including buildings, transportation and other sectors. The United States Department of Energy (DOE), through Pacific Northwest National Laboratory (PNNL) provided technical assistance to Seattle in order to understand the implications of one potential direction for its code development, limiting trade-offs of long-lived building envelope components less stringent than the prescriptive code envelope requirements by using better-than-code but shorter-lived lighting and heating, ventilation, and air-conditioning (HVAC) components through the total building performance modeled energy compliance path. Weaker building envelopes can permanently limit building energy performance even as lighting and HVAC components are upgraded over time, because retrofitting the envelope is less likely and more expensive. Weaker building envelopes may also increase the required size, cost and complexity of HVAC systems and may adversely affect occupant comfort. This report presents the results of this technical assistance. The use of modeled energy code compliance to trade-off envelope components with shorter-lived building components is not unique to Seattle and the lessons and possible solutions described in this report have implications for other jurisdictions and energy codes.

  20. Optimal delivery of aerosols to infants during mechanical ventilation.

    Science.gov (United States)

    Longest, P Worth; Azimi, Mandana; Hindle, Michael

    2014-10-01

    The objective of this study was to determine optimal aerosol delivery conditions for a full-term (3.6 kg) infant receiving invasive mechanical ventilation by evaluating the effects of aerosol particle size, a new wye connector, and timing of aerosol delivery. In vitro experiments used a vibrating mesh nebulizer and evaluated drug deposition fraction and emitted dose through ventilation circuits containing either a commercial (CM) or new streamlined (SL) wye connector and 3-mm endotracheal tube (ETT) for aerosols with mass median aerodynamic diameters of 880 nm, 1.78 μm, and 4.9 μm. The aerosol was released into the circuit either over the full inhalation cycle (T1 delivery) or over the first half of inhalation (T2 delivery). Validated computational fluid dynamics (CFD) simulations and whole-lung model predictions were used to assess lung deposition and exhaled dose during cyclic ventilation. In vitro experiments at a steady-state tracheal flow rate of 5 L/min resulted in 80-90% transmission of the 880-nm and 1.78-μm aerosols from the ETT. Based on CFD simulations with cyclic ventilation, the SL wye design reduced depositional losses in the wye by a factor of approximately 2-4 and improved lung delivery efficiencies by a factor of approximately 2 compared with the CM device. Delivery of the aerosol over the first half of the inspiratory cycle (T2) reduced exhaled dose from the ventilation circuit by a factor of 4 compared with T1 delivery. Optimal lung deposition was achieved with the SL wye connector and T2 delivery, resulting in 45% and 60% lung deposition for optimal polydisperse (∼1.78 μm) and monodisperse (∼2.5 μm) particle sizes, respectively. Optimization of selected factors and use of a new SL wye connector can substantially increase the lung delivery efficiency of medical aerosols to infants from current values of <1-10% to a range of 45-60%.

  1. HETERO code, heterogeneous procedure for reactor calculation

    International Nuclear Information System (INIS)

    Jovanovic, S.M.; Raisic, N.M.

    1966-11-01

    This report describes the procedure for calculating the parameters of heterogeneous reactor system taking into account the interaction between fuel elements related to established geometry. First part contains the analysis of single fuel element in a diffusion medium, and criticality condition of the reactor system described by superposition of elements interactions. the possibility of performing such analysis by determination of heterogeneous system lattice is described in the second part. Computer code HETERO with the code KETAP (calculation of criticality factor η n and flux distribution) is part of this report together with the example of RB reactor square lattice

  2. Benchmark calculation of subchannel analysis codes

    International Nuclear Information System (INIS)

    1996-02-01

    In order to evaluate the analysis capabilities of various subchannel codes used in thermal-hydraulic design of light water reactors, benchmark calculations were performed. The selected benchmark problems and major findings obtained by the calculations were as follows: (1)As for single-phase flow mixing experiments between two channels, the calculated results of water temperature distribution along the flow direction were agreed with experimental results by tuning turbulent mixing coefficients properly. However, the effect of gap width observed in the experiments could not be predicted by the subchannel codes. (2)As for two-phase flow mixing experiments between two channels, in high water flow rate cases, the calculated distributions of air and water flows in each channel were well agreed with the experimental results. In low water flow cases, on the other hand, the air mixing rates were underestimated. (3)As for two-phase flow mixing experiments among multi-channels, the calculated mass velocities at channel exit under steady-state condition were agreed with experimental values within about 10%. However, the predictive errors of exit qualities were as high as 30%. (4)As for critical heat flux(CHF) experiments, two different results were obtained. A code indicated that the calculated CHF's using KfK or EPRI correlations were well agreed with the experimental results, while another code suggested that the CHF's were well predicted by using WSC-2 correlation or Weisman-Pei mechanistic model. (5)As for droplets entrainment and deposition experiments, it was indicated that the predictive capability was significantly increased by improving correlations. On the other hand, a remarkable discrepancy between codes was observed. That is, a code underestimated the droplet flow rate and overestimated the liquid film flow rate in high quality cases, while another code overestimated the droplet flow rate and underestimated the liquid film flow rate in low quality cases. (J.P.N.)

  3. Efficient File Sharing by Multicast - P2P Protocol Using Network Coding and Rank Based Peer Selection

    Science.gov (United States)

    Stoenescu, Tudor M.; Woo, Simon S.

    2009-01-01

    In this work, we consider information dissemination and sharing in a distributed peer-to-peer (P2P highly dynamic communication network. In particular, we explore a network coding technique for transmission and a rank based peer selection method for network formation. The combined approach has been shown to improve information sharing and delivery to all users when considering the challenges imposed by the space network environments.

  4. Multifunctional Nanoparticles for Drug Delivery Applications Imaging, Targeting, and Delivery

    CERN Document Server

    Prud'homme, Robert

    2012-01-01

    This book clearly demonstrates the progression of nanoparticle therapeutics from basic research to applications. Unlike other books covering nanoparticles used in medical applications, Multifunctional Nanoparticles for Drug Delivery Applications presents the medical challenges that can be reduced or even overcome by recent advances in nanoscale drug delivery. Each chapter highlights recent progress in the design and engineering of select multifunctional nanoparticles with topics covering targeting, imaging, delivery, diagnostics, and therapy.

  5. Calculation code of mass and heat transfer in a pulsed column for Purex process

    International Nuclear Information System (INIS)

    Tsukada, Takeshi; Takahashi, Keiki

    1993-01-01

    A calculation code for extraction behavior analysis in a pulsed column employed at an extraction process of a reprocessing plant was developed. This code was also combined with our previously developed calculation code for axial temperature profiles in a pulsed column. The one-dimensional dispersion model was employed for both of the extraction behavior analysis and the axial temperature profile analysis. The reported values of the fluid characteristics coefficient, the transfer coefficient and the diffusivities in the pulsed column were used. The calculated concentration profiles of HNO 3 , U and Pu for the steady state have a good agreement with the reported experimental results. The concentration and temperature profiles were calculated under the operation conditions which induce the abnormal U extraction behavior, i.e. U extraction zone is moved to the bottom of the column. Thought there is slight difference between calculated and experimental value, it is appeared that our developed code can be applied to the simulation under the normal operation condition and the relatively slowly transient condition. Pu accumulation phenomena was analyzed with this code and the accumulation tendency is similar to the reported analysis results. (author)

  6. The ELOCA fuel modelling code: past, present and future

    International Nuclear Information System (INIS)

    Williams, A.F.

    2005-01-01

    ELOCA is the Industry Standard Toolset (IST) computer code for modelling CANDU fuel under the transient coolant conditions typical of an accident scenario. Since its original inception in the early 1970's, the code has undergone continual development and improvement. The code now embodies much of the knowledge and experience of fuel behaviour gained by the Canadian nuclear industry over this period. ELOCA has proven to be a valuable tool for the safety analyst, and continues to be used extensively to support the licensing cases of CANDU reactors. This paper provides a brief and much simplified view of this development history, its current status, and plans for future development. (author)

  7. RODMOD: a code for control rod positioning

    International Nuclear Information System (INIS)

    Vondy, D.R.; Fowler, T.B.

    1978-11-01

    The report documents a computer code which has been implemented to position control rods according to a prescribed schedule during the calculation of a reactor history. Control rods may be represented explicitly with or without internal black absorber conditions in selected energy groups, or fractional insertion may be done, or both, in a problem. There is provision for control rod follower, movement of materials through a series of zones in a closed loop, and shutdown rod insertion and subsequent removal to allow the reactor history calculation to be continued. This code is incorporated in the system containing the VENTURE diffusion theory neutronics and the BURNER exposure codes for routine use. The implemented automated procedures cause the prescribed control rod insertion schedule to be applied without the access of additional user input data during the calculation of a reactor operating history

  8. Analysis of quantum error-correcting codes: Symplectic lattice codes and toric codes

    Science.gov (United States)

    Harrington, James William

    Quantum information theory is concerned with identifying how quantum mechanical resources (such as entangled quantum states) can be utilized for a number of information processing tasks, including data storage, computation, communication, and cryptography. Efficient quantum algorithms and protocols have been developed for performing some tasks (e.g. , factoring large numbers, securely communicating over a public channel, and simulating quantum mechanical systems) that appear to be very difficult with just classical resources. In addition to identifying the separation between classical and quantum computational power, much of the theoretical focus in this field over the last decade has been concerned with finding novel ways of encoding quantum information that are robust against errors, which is an important step toward building practical quantum information processing devices. In this thesis I present some results on the quantum error-correcting properties of oscillator codes (also described as symplectic lattice codes) and toric codes. Any harmonic oscillator system (such as a mode of light) can be encoded with quantum information via symplectic lattice codes that are robust against shifts in the system's continuous quantum variables. I show the existence of lattice codes whose achievable rates match the one-shot coherent information over the Gaussian quantum channel. Also, I construct a family of symplectic self-dual lattices and search for optimal encodings of quantum information distributed between several oscillators. Toric codes provide encodings of quantum information into two-dimensional spin lattices that are robust against local clusters of errors and which require only local quantum operations for error correction. Numerical simulations of this system under various error models provide a calculation of the accuracy threshold for quantum memory using toric codes, which can be related to phase transitions in certain condensed matter models. I also present

  9. Solid lipid nanoparticles for pulmonary delivery of insulin.

    Science.gov (United States)

    Liu, Jie; Gong, Tao; Fu, Hualin; Wang, Changguang; Wang, Xiuli; Chen, Qian; Zhang, Qin; He, Qin; Zhang, Zhirong

    2008-05-22

    Growing attention has been given to the potential of pulmonary route as an alternative for non-invasive systemic delivery of therapeutic agents. In this study, novel nebulizer-compatible solid lipid nanoparticles (SLNs) for pulmonary drug delivery of insulin were developed by reverse micelle-double emulsion method. The influences of the amount of sodium cholate (SC) and soybean phosphatidylcholine (SPC) on the deposition properties of the nanoparticles were investigated. Under optimal conditions, the entrapment delivery (ED), respirable fraction (RF) and nebulization efficiency (NE) of SLNs could reach 96.53, 82.11 and 63.28%, respectively, and Ins-SLNs remained stable during nebulization. Fasting plasma glucose level was reduced to 39.41% and insulin level was increased to approximately 170 microIU/ml 4h after pulmonary administration of 20 IU/kg Ins-SLNs. A pharmacological bioavailability of 24.33% and a relative bioavailability of 22.33% were obtained using subcutaneous injection as a reference. Incorporating fluorescent-labelled insulin into SLNs, we found that the SLNs were effectively and homogeneously distributed in the lung alveoli. These findings suggested that SLNs could be used as a potential carrier for pulmonary delivery of insulin by improving both in vitro and in vivo stability as well as prolonging hypoglycemic effect, which inevitably resulted in enhanced bioavailability.

  10. Multi-protein delivery by nanodiamonds promotes bone formation.

    Science.gov (United States)

    Moore, L; Gatica, M; Kim, H; Osawa, E; Ho, D

    2013-11-01

    Bone morphogenetic proteins (BMPs) are well-studied regulators of cartilage and bone development that have been Food and Drug Administration (FDA)-approved for the promotion of bone formation in certain procedures. BMPs are seeing more use in oral and maxillofacial surgeries because of recent FDA approval of InFUSE(®) for sinus augmentation and localized alveolar ridge augmentation. However, the utility of BMPs in medical and dental applications is limited by the delivery method. Currently, BMPs are delivered to the surgical site by the implantation of bulky collagen sponges. Here we evaluate the potential of detonation nanodiamonds (NDs) as a delivery vehicle for BMP-2 and basic fibroblast growth factor (bFGF). Nanodiamonds are biocompatible, 4- to 5-nm carbon nanoparticles that have previously been used to deliver a wide variety of molecules, including proteins and peptides. We find that both BMP-2 and bFGF are readily loaded onto NDs by physisorption, forming a stable colloidal solution, and are triggered to release in slightly acidic conditions. Simultaneous delivery of BMP-2 and bFGF by ND induces differentiation and proliferation in osteoblast progenitor cells. Overall, we find that NDs provide an effective injectable alternative for the delivery of BMP-2 and bFGF to promote bone formation.

  11. Effect of milk sample delivery methods and arrival conditions on bacterial contamination rates.

    Science.gov (United States)

    Dinsmore, R P; English, P B; Matthews, J C; Sears, P M

    1990-07-01

    A cross sectional study was performed of factors believed to contribute to the contamination of bovine milk sample cultures submitted to the Ithaca Regional Laboratory of the Quality Milk Promotion Services/New York State Mastitis Control. Of 871 samples entered in the study, 137 (15.7%) were contaminated. There were interactions between the sample source (veterinarian vs dairyman), delivery method, and time between sample collection and arrival at the laboratory. If only those samples collected and hand delivered by the dairyman within 1 day of collection were compared to a like subset of samples collected and hand delivered by veterinarians, no statistically significant differences in milk sample contamination rate (MSCR) were found. Samples were delivered to the laboratory by hand, US Postal Service, United Parcel Service, via the New York State College of Veterinary Medicine Diagnostic Laboratory, or Northeast Dairy Herd Improvement Association Courier. The MSCR was only 7.6% for hand delivered samples, while 26% of Postal Service samples were contaminated. These rates differed significantly from other delivery methods (P less than 0.0001). The USPS samples arrived a longer time after sampling than did samples sent by other routes, and time had a significant effect on MSCR (0 to 1 day, 8.9%; greater than 1 day, 25.9%; P less than 0.01). Samples packaged with ice packs sent by routes other than the Postal Service had a lower MSCR than those not packaged with ice packs, but ice packs did not reduce the MSCR for samples sent by the Postal Service.(ABSTRACT TRUNCATED AT 250 WORDS)

  12. The MCU-RFFI Monte Carlo code for reactor design applications

    International Nuclear Information System (INIS)

    Gomin, E.A.; Maiorov, L.V.

    1995-01-01

    MCU-RFFI is a general-purpose, continuous-energy, general geometry Monte Carlo code for solving external source or criticality problems for neutron transport in the energy range of 20 MeV to 10 -5 eV. The main fields of MCU-RFFI applications are as follows: (a) nuclear data validation; (b) design calculations (space reactors and other); (c) verification of design codes. MCU-RFFI is also supplied with tools to check the accuracy of design codes. These tools permit the user to calculate: the few group parameters of reactor cells, including the diffusion coefficients defined in a variety of ways, reaction rates for various nuclei, energy and space bins, and the kinetic parameters of systems, taking into account delayed neutrons. Boundary conditions include vacuum, white and specular reflection, and the condition of translational symmetry. The criticals with the neutron leakage given by the buckling vector may be calculated by solving Benoist's problem. The curve of criticality coefficient dependence on buckling may be determined during the single code run and critical buckling may be determined. Double heterogeneous systems with fuel elements containing many thousands of spherical microcells can be solved

  13. Chitosan microspheres in novel drug delivery systems.

    Science.gov (United States)

    Mitra, Analava; Dey, Baishakhi

    2011-07-01

    The main aim in the drug therapy of any disease is to attain the desired therapeutic concentration of the drug in plasma or at the site of action and maintain it for the entire duration of treatment. A drug on being used in conventional dosage forms leads to unavoidable fluctuations in the drug concentration leading to under medication or overmedication and increased frequency of dose administration as well as poor patient compliance. To minimize drug degradation and loss, to prevent harmful side effects and to increase drug bioavailability various drug delivery and drug targeting systems are currently under development. Handling the treatment of severe disease conditions has necessitated the development of innovative ideas to modify drug delivery techniques. Drug targeting means delivery of the drug-loaded system to the site of interest. Drug carrier systems include polymers, micelles, microcapsules, liposomes and lipoproteins to name some. Different polymer carriers exert different effects on drug delivery. Synthetic polymers are usually non-biocompatible, non-biodegradable and expensive. Natural polymers such as chitin and chitosan are devoid of such problems. Chitosan comes from the deacetylation of chitin, a natural biopolymer originating from crustacean shells. Chitosan is a biocompatible, biodegradable, and nontoxic natural polymer with excellent film-forming ability. Being of cationic character, chitosan is able to react with polyanions giving rise to polyelectrolyte complexes. Hence chitosan has become a promising natural polymer for the preparation of microspheres/nanospheres and microcapsules. The techniques employed to microencapsulate with chitosan include ionotropic gelation, spray drying, emulsion phase separation, simple and complex coacervation. This review focuses on the preparation, characterization of chitosan microspheres and their role in novel drug delivery systems.

  14. Coding for dummies

    CERN Document Server

    Abraham, Nikhil

    2015-01-01

    Hands-on exercises help you learn to code like a pro No coding experience is required for Coding For Dummies,your one-stop guide to building a foundation of knowledge inwriting computer code for web, application, and softwaredevelopment. It doesn't matter if you've dabbled in coding or neverwritten a line of code, this book guides you through the basics.Using foundational web development languages like HTML, CSS, andJavaScript, it explains in plain English how coding works and whyit's needed. Online exercises developed by Codecademy, a leading online codetraining site, help hone coding skill

  15. Benchmarking Severe Accident Computer Codes for Heavy Water Reactor Applications

    International Nuclear Information System (INIS)

    2013-12-01

    Requests for severe accident investigations and assurance of mitigation measures have increased for operating nuclear power plants and the design of advanced nuclear power plants. Severe accident analysis investigations necessitate the analysis of the very complex physical phenomena that occur sequentially during various stages of accident progression. Computer codes are essential tools for understanding how the reactor and its containment might respond under severe accident conditions. The IAEA organizes coordinated research projects (CRPs) to facilitate technology development through international collaboration among Member States. The CRP on Benchmarking Severe Accident Computer Codes for HWR Applications was planned on the advice and with the support of the IAEA Nuclear Energy Department's Technical Working Group on Advanced Technologies for HWRs (the TWG-HWR). This publication summarizes the results from the CRP participants. The CRP promoted international collaboration among Member States to improve the phenomenological understanding of severe core damage accidents and the capability to analyse them. The CRP scope included the identification and selection of a severe accident sequence, selection of appropriate geometrical and boundary conditions, conduct of benchmark analyses, comparison of the results of all code outputs, evaluation of the capabilities of computer codes to predict important severe accident phenomena, and the proposal of necessary code improvements and/or new experiments to reduce uncertainties. Seven institutes from five countries with HWRs participated in this CRP

  16. Performance analysis of data delivery schemes for a multi-sink wireless sensor network

    NARCIS (Netherlands)

    Tan, H.P.; Gabor, A.F.; Seah, W.K.G.; Lee, P.W.Q.

    2008-01-01

    Wireless sensor networks are expected to be deployed in harsh environments characterised by extremely poor and fluctuating channel conditions. With the commonly adopted single-sink architecture, such conditions are exemplified by contention near the sink as a result of multipath delivery. This may

  17. Improvement on reaction model for sodium-water reaction jet code and application analysis

    International Nuclear Information System (INIS)

    Itooka, Satoshi; Saito, Yoshinori; Okabe, Ayao; Fujimata, Kazuhiro; Murata, Shuuichi

    2000-03-01

    In selecting the reasonable DBL on steam generator (SG), it is necessary to improve analytical method for estimating the sodium temperature on failure propagation due to overheating. Improvement on sodium-water reaction (SWR) jet code (LEAP-JET ver.1.30) and application analysis to the water injection tests for confirmation of code propriety were performed. On the improvement of the code, a gas-liquid interface area density model was introduced to develop a chemical reaction model with a little dependence on calculation mesh size. The test calculation using the improved code (LEAP-JET ver.1.40) were carried out with conditions of the SWAT-3·Run-19 test and an actual scale SG. It is confirmed that the SWR jet behavior on the results and the influence to analysis result of a model are reasonable. For the application analysis to the water injection tests, water injection behavior and SWR jet behavior analyses on the new SWAT-1 (SWAT-1R) and SWAT-3 (SWAT-3R) tests were performed using the LEAP-BLOW code and the LEAP-JET code. In the application analysis of the LEAP-BLOW code, parameter survey study was performed. As the results, the condition of the injection nozzle diameter needed to simulate the water leak rate was confirmed. In the application analysis of the LEAP-JET code, temperature behavior of the SWR jet was investigated. (author)

  18. State of art in FE-based fuel performance codes

    International Nuclear Information System (INIS)

    Kim, Hyo Chan; Yang, Yong Sik; Kim, Dae Ho; Bang, Je Geon; Kim, Sun Ki; Koo, Yang Hyun

    2013-01-01

    Fuel performance codes approximate this complex behavior using an axisymmetric, axially-stacked, one-dimensional radial representation to save computation cost. However, the need for improved modeling of PCMI and, particularly, the importance of multidimensional capability for accurate fuel performance simulation has been identified as safety margin decreases. Finite element (FE) method that is reliable and proven solution in mechanical field has been introduced into fuel performance codes for multidimensional analysis. The present state of the art in numerical simulation of FE-based fuel performance predominantly involves 2-D axisymmetric model and 3-D volumetric model. The FRAPCON and FRAPTRAN own 1.5-D and 2-D FE model to simulate PCMI and cladding ballooning. In 2-D simulation, the FALCON code, developed by EPRI, is a 2-D (R-Z and R-θ) fully thermal-mechanically coupled steady-state and transient FE-based fuel behavior code. The French codes TOUTATIS and ALCYONE which are 3-D, and typically used to investigate localized behavior. In 2008, the Idaho National Laboratory (INL) has been developing multidimensional (2-D and 3-D) nuclear fuel performance code called BISON. In this paper, the current state of FE-based fuel performance code and their models are presented. Based on investigation into the codes, requirements and direction of development for new FE-based fuel performance code can be discussed. Based on comparison of models in FE-based fuel performance code, status of art in the codes can be discussed. A new FE-based fuel performance code should include typical pellet and cladding models which all codes own. In particular, specified pellet and cladding model such as gaseous swelling and high burnup structure (HBS) model should be developed to improve accuracy of code as well as consider AC condition. To reduce computation cost, the approximated gap and the optimized contact model should be also developed

  19. Development of parallel Fokker-Planck code ALLAp

    International Nuclear Information System (INIS)

    Batishcheva, A.A.; Sigmar, D.J.; Koniges, A.E.

    1996-01-01

    We report on our ongoing development of the 3D Fokker-Planck code ALLA for a highly collisional scrape-off-layer (SOL) plasma. A SOL with strong gradients of density and temperature in the spatial dimension is modeled. Our method is based on a 3-D adaptive grid (in space, magnitude of the velocity, and cosine of the pitch angle) and a second order conservative scheme. Note that the grid size is typically 100 x 257 x 65 nodes. It was shown in our previous work that only these capabilities make it possible to benchmark a 3D code against a spatially-dependent self-similar solution of a kinetic equation with the Landau collision term. In the present work we show results of a more precise benchmarking against the exact solutions of the kinetic equation using a new parallel code ALLAp with an improved method of parallelization and a modified boundary condition at the plasma edge. We also report first results from the code parallelization using Message Passing Interface for a Massively Parallel CRI T3D platform. We evaluate the ALLAp code performance versus the number of T3D processors used and compare its efficiency against a Work/Data Sharing parallelization scheme and a workstation version

  20. Detecting non-coding selective pressure in coding regions

    Directory of Open Access Journals (Sweden)

    Blanchette Mathieu

    2007-02-01

    Full Text Available Abstract Background Comparative genomics approaches, where orthologous DNA regions are compared and inter-species conserved regions are identified, have proven extremely powerful for identifying non-coding regulatory regions located in intergenic or intronic regions. However, non-coding functional elements can also be located within coding region, as is common for exonic splicing enhancers, some transcription factor binding sites, and RNA secondary structure elements affecting mRNA stability, localization, or translation. Since these functional elements are located in regions that are themselves highly conserved because they are coding for a protein, they generally escaped detection by comparative genomics approaches. Results We introduce a comparative genomics approach for detecting non-coding functional elements located within coding regions. Codon evolution is modeled as a mixture of codon substitution models, where each component of the mixture describes the evolution of codons under a specific type of coding selective pressure. We show how to compute the posterior distribution of the entropy and parsimony scores under this null model of codon evolution. The method is applied to a set of growth hormone 1 orthologous mRNA sequences and a known exonic splicing elements is detected. The analysis of a set of CORTBP2 orthologous genes reveals a region of several hundred base pairs under strong non-coding selective pressure whose function remains unknown. Conclusion Non-coding functional elements, in particular those involved in post-transcriptional regulation, are likely to be much more prevalent than is currently known. With the numerous genome sequencing projects underway, comparative genomics approaches like that proposed here are likely to become increasingly powerful at detecting such elements.

  1. Colloidal drug delivery system: amplify the ocular delivery.

    Science.gov (United States)

    Ali, Javed; Fazil, Mohd; Qumbar, Mohd; Khan, Nazia; Ali, Asgar

    2016-01-01

    The ocular perceivers are the most voluntarily accessible organs in terms of location in the body, yet drug distribution to these tissues is one of the most intriguing and challenging endeavors and problematic to the pharmaceutical scientist. The most of ocular diseases are treated with topical application of conventional formulation, i.e. solutions, suspensions and ointment. Typically on installation of these conventional formulations, only <5% of the applied dose penetrates the cornea and reaches intraocular tissues, while a major fraction of the instilled dose is wastage due to the presence of many ocular barriers like external barriers, rapid loss of the instilled solution from the precorneal area and nasolacrimal drainage system. Systemic absorption caused systemic side effects varying from mild to life-threatening events. The main objective of this review is to explore the role of colloidal delivery of drug to minimize the drawbacks associated with them. This review provides an insight into the various constraints associated with ocular drug delivery, summarizes recent findings and applications of colloidal delivery systems, i.e. nanoparticles, nanosuspensions, liposomes, niosomes, dendrimers and contact lenses containing nanoparticles have the capacity to distribute ocular drugs to categorical target sites and hold promise to revolutionize the therapy of many ocular perceiver diseases and minimized the circumscription of conventional delivery. Form the basis of literature review, it has been found that the novel delivery system have greater impact to maximize ocular drug absorption, and minimize systemic absorption and side effects.

  2. Lossless, Near-Lossless, and Refinement Coding of Bi-level Images

    DEFF Research Database (Denmark)

    Martins, Bo; Forchhammer, Søren Otto

    1997-01-01

    We present general and unified algorithms for lossy/lossless codingof bi-level images. The compression is realized by applying arithmetic coding to conditional probabilities. As in the current JBIG standard the conditioning may be specified by a template.For better compression, the more general....... Introducing only a small amount of loss in halftoned test images, compression is increased by up to a factor of four compared with JBIG. Lossy, lossless, and refinement decoding speed and lossless encoding speed are less than a factor of two slower than JBIG. The (de)coding method is proposed as part of JBIG......-2, an emerging international standard for lossless/lossy compression of bi-level images....

  3. Dynamic Shannon Coding

    OpenAIRE

    Gagie, Travis

    2005-01-01

    We present a new algorithm for dynamic prefix-free coding, based on Shannon coding. We give a simple analysis and prove a better upper bound on the length of the encoding produced than the corresponding bound for dynamic Huffman coding. We show how our algorithm can be modified for efficient length-restricted coding, alphabetic coding and coding with unequal letter costs.

  4. Qualification of FEAST 3.0 and FEAT 4.0 computer codes

    International Nuclear Information System (INIS)

    Xu, Z.; Lai, L.; Sim, K.-S.; Huang, F.; Wong, B.

    2005-01-01

    FEAST (Finite Element Analysis for Stresses) is an AECL computer code used to assess the structural integrity of the CANDU fuel element. FEAST models the thermo-elastic, thermo-elasto-plastic and creep deformations in CANDU fuel. FEAT (Finite Element Analysis for Temperature) is another AECL computer code and is used to assess the thermal integrity of fuel elements. FEAT models the steady-state and transient heat flows in CANDU fuel, under conditions such as flux depression, end flux peaking, temperature-dependent thermal conductivity, and non-uniform time-dependent boundary conditions. Both computer programs are used in design and qualification analyses of CANDU fuel. Formal qualifications (including coding verification and validation) of both codes were performed, in accordance with AECL software quality assurance (SQA) manual and procedures that are consistent with CSA N286.7-99. Validation of FEAST 3.0 shows very good agreement with independent analytical solutions or measurements. Validation of FEAT 4.0 also shows very good agreement with independent WIMS-AECL calculations, analytical solutions, ANSYS calculations and measurement. (author)

  5. Qualification of FEAST 3.0 and FEAT 4.0 computer codes

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Z.; Lai, L.; Sim, K.-S.; Huang, F.; Wong, B. [Atomic Energy of Canada Limited, Mississauga, Ontario (Canada)

    2005-07-01

    FEAST (Finite Element Analysis for Stresses) is an AECL computer code used to assess the structural integrity of the CANDU fuel element. FEAST models the thermo-elastic, thermo-elasto-plastic and creep deformations in CANDU fuel. FEAT (Finite Element Analysis for Temperature) is another AECL computer code and is used to assess the thermal integrity of fuel elements. FEAT models the steady-state and transient heat flows in CANDU fuel, under conditions such as flux depression, end flux peaking, temperature-dependent thermal conductivity, and non-uniform time-dependent boundary conditions. Both computer programs are used in design and qualification analyses of CANDU fuel. Formal qualifications (including coding verification and validation) of both codes were performed, in accordance with AECL software quality assurance (SQA) manual and procedures that are consistent with CSA N286.7-99. Validation of FEAST 3.0 shows very good agreement with independent analytical solutions or measurements. Validation of FEAT 4.0 also shows very good agreement with independent WIMS-AECL calculations, analytical solutions, ANSYS calculations and measurement. (author)

  6. The correspondence between projective codes and 2-weight codes

    NARCIS (Netherlands)

    Brouwer, A.E.; Eupen, van M.J.M.; Tilborg, van H.C.A.; Willems, F.M.J.

    1994-01-01

    The hyperplanes intersecting a 2-weight code in the same number of points obviously form the point set of a projective code. On the other hand, if we have a projective code C, then we can make a 2-weight code by taking the multiset of points E PC with multiplicity "Y(w), where W is the weight of

  7. General features of the neutronics design code EQUICYCLE

    International Nuclear Information System (INIS)

    Jirlow, K.

    1978-10-01

    The neutronics code EQUICYCLE has been developed and improved over a long period of time. It is expecially adapted to survey type design calculations of large fast power reactors with particular emphasis on the nuclear parameters for a realistic equilibrium fuel cycle. Thus the code is used to evaluate the breeding performance, the power distributions and the uranium and plutonium mass balance for realistic refuelling schemes. In addition reactivity coefficients can be calculated and the influence of burnup could be assessed. The code is two-dimensional and treats the reactor core in R-Z geometry. The basic ideas of the calculating scheme are successive iterative improvement of cross-section sets and flux spectra and use of the mid-cycle flux for burning the fuel according to a specified refuelling scheme. Normally given peak burn-ups and maximum power densities are used as boundary conditions. The code is capable of handling the unconventional, so called heterogeneous cores. (author)

  8. Neonatal outcomes and operative vaginal delivery versus cesarean delivery.

    LENUS (Irish Health Repository)

    Contag, Stephen A

    2010-06-01

    We compared outcomes for neonates with forceps-assisted, vacuum-assisted, or cesarean delivery in the second stage of labor. This is a secondary analysis of a randomized trial in laboring, low-risk, nulliparous women at >or=36 weeks\\' gestation. Neonatal outcomes after use of forceps, vacuum, and cesarean were compared among women in the second stage of labor at station +1 or below (thirds scale) for failure of descent or nonreassuring fetal status. Nine hundred ninety women were included in this analysis: 549 (55%) with an indication for delivery of failure of descent and 441 (45%) for a nonreassuring fetal status. Umbilical cord gases were available for 87% of neonates. We found no differences in the base excess (P = 0.35 and 0.78 for failure of descent and nonreassuring fetal status) or frequencies of pH below 7.0 (P = 0.73 and 0.34 for failure of descent and nonreassuring fetal status) among the three delivery methods. Birth outcomes and umbilical cord blood gas values were similar for those neonates with a forceps-assisted, vacuum-assisted, or cesarean delivery in the second stage of labor. The occurrence of significant fetal acidemia was not different among the three delivery methods regardless of the indication.

  9. Protein Nanoparticles as Drug Delivery Carriers for Cancer Therapy

    Directory of Open Access Journals (Sweden)

    Warangkana Lohcharoenkal

    2014-01-01

    Full Text Available Nanoparticles have increasingly been used for a variety of applications, most notably for the delivery of therapeutic and diagnostic agents. A large number of nanoparticle drug delivery systems have been developed for cancer treatment and various materials have been explored as drug delivery agents to improve the therapeutic efficacy and safety of anticancer drugs. Natural biomolecules such as proteins are an attractive alternative to synthetic polymers which are commonly used in drug formulations because of their safety. In general, protein nanoparticles offer a number of advantages including biocompatibility and biodegradability. They can be prepared under mild conditions without the use of toxic chemicals or organic solvents. Moreover, due to their defined primary structure, protein-based nanoparticles offer various possibilities for surface modifications including covalent attachment of drugs and targeting ligands. In this paper, we review the most significant advancements in protein nanoparticle technology and their use in drug delivery arena. We then examine the various sources of protein materials that have been used successfully for the construction of protein nanoparticles as well as their methods of preparation. Finally, we discuss the applications of protein nanoparticles in cancer therapy.

  10. Protein nanoparticles as drug delivery carriers for cancer therapy.

    Science.gov (United States)

    Lohcharoenkal, Warangkana; Wang, Liying; Chen, Yi Charlie; Rojanasakul, Yon

    2014-01-01

    Nanoparticles have increasingly been used for a variety of applications, most notably for the delivery of therapeutic and diagnostic agents. A large number of nanoparticle drug delivery systems have been developed for cancer treatment and various materials have been explored as drug delivery agents to improve the therapeutic efficacy and safety of anticancer drugs. Natural biomolecules such as proteins are an attractive alternative to synthetic polymers which are commonly used in drug formulations because of their safety. In general, protein nanoparticles offer a number of advantages including biocompatibility and biodegradability. They can be prepared under mild conditions without the use of toxic chemicals or organic solvents. Moreover, due to their defined primary structure, protein-based nanoparticles offer various possibilities for surface modifications including covalent attachment of drugs and targeting ligands. In this paper, we review the most significant advancements in protein nanoparticle technology and their use in drug delivery arena. We then examine the various sources of protein materials that have been used successfully for the construction of protein nanoparticles as well as their methods of preparation. Finally, we discuss the applications of protein nanoparticles in cancer therapy.

  11. Quality Improvement of MARS Code and Establishment of Code Coupling

    International Nuclear Information System (INIS)

    Chung, Bub Dong; Jeong, Jae Jun; Kim, Kyung Doo

    2010-04-01

    The improvement of MARS code quality and coupling with regulatory auditing code have been accomplished for the establishment of self-reliable technology based regulatory auditing system. The unified auditing system code was realized also by implementing the CANDU specific models and correlations. As a part of the quality assurance activities, the various QA reports were published through the code assessments. The code manuals were updated and published a new manual which describe the new models and correlations. The code coupling methods were verified though the exercise of plant application. The education-training seminar and technology transfer were performed for the code users. The developed MARS-KS is utilized as reliable auditing tool for the resolving the safety issue and other regulatory calculations. The code can be utilized as a base technology for GEN IV reactor applications

  12. The synergistic effect of breastfeeding discontinuation and cesarean section delivery on postpartum depression: A nationwide population-based cohort study in Korea.

    Science.gov (United States)

    Nam, Jin Young; Choi, Young; Kim, Juyeong; Cho, Kyoung Hee; Park, Eun-Cheol

    2017-08-15

    The relationships between breastfeeding discontinuation and cesarean section delivery, and the occurrence of postpartum depression (PPD) remain unclear. Therefore, we aimed to investigate the association of breastfeeding discontinuation and cesarean section delivery with PPD during the first 6 months after delivery. Data were extracted from the Korean National Health Insurance Service-National Sample Cohort for 81,447 women who delivered during 2004-2013. PPD status was determined using the diagnosis code at outpatient or inpatient visit during the 6-month postpartum period. Breastfeeding discontinuation and cesarean section delivery were identified from prescription of lactation suppression drugs and diagnosis, respectively. Cox proportional hazards models were used to calculate adjusted hazard ratios. Of the 81,447 women, 666 (0.82%) had PPD. PPD risk was higher in women who discontinued breastfeeding than in those who continued breastfeeding (hazard ratio=3.23, Pwomen with cesarean section delivery than in those with vaginal delivery (hazard ratio=1.26, P=0.0040), and in women with cesarean section delivery who discontinued breastfeeding than in those with vaginal delivery who continued breastfeeding (hazard ratio=4.92, Pworking status, which could introduce selection bias and errors due to miscoding; and potential lack of adjustment for important confounders. Breastfeeding discontinuation and cesarean section delivery were associated with PPD during the 6-month postpartum period. Our results support the implementation of breastfeeding promoting policies, and PPD screening and treatment programs during the early postpartum period. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. Light water reactor fuel analysis code FEMAXI-7. Model and structure [Revised edition

    International Nuclear Information System (INIS)

    Suzuki, Motoe; Udagawa, Yutaka; Amaya, Masaki; Saitou, Hiroaki

    2014-03-01

    A light water reactor fuel analysis code FEMAXI-7 has been developed for the purpose of analyzing the fuel behavior in both normal conditions and anticipated transient conditions. This code is an advanced version which has been produced by incorporating the former version FEMAXI-6 with numerous functional improvements and extensions. In FEMAXI-7, many new models have been added and parameters have been clearly arranged. Also, to facilitate effective maintenance and accessibility of the code, modularization of subroutines and functions have been attained, and quality comment descriptions of variables or physical quantities have been incorporated in the source code. With these advancements, the FEMAXI-7 code has been upgraded to a versatile analytical tool for high burnup fuel behavior analyses. This report is the revised edition of the first one which describes in detail the design, basic theory and structure, models and numerical method, and improvements and extensions. The first edition, JAEA-Data/Code 2010-035, was published in 2010. The first edition was extended by orderly addition and disposition of explanations of models and organized as the revised edition after three years interval. (author)

  14. Assisted delivery with forceps

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/patientinstructions/000509.htm Assisted delivery with forceps To use the sharing features on ... called vacuum assisted delivery . When is a Forceps Delivery Needed? Even after your cervix is fully dilated ( ...

  15. Generalized rank weights of reducible codes, optimal cases and related properties

    DEFF Research Database (Denmark)

    Martinez Peñas, Umberto

    2018-01-01

    in network coding. In this paper, we study their security behavior against information leakage on networks when applied as coset coding schemes, giving the following main results: 1) we give lower and upper bounds on their generalized rank weights (GRWs), which measure worst case information leakage...... to the wire tapper; 2) we find new parameters for which these codes are MRD (meaning that their first GRW is optimal) and use the previous bounds to estimate their higher GRWs; 3) we show that all linear (over the extension field) codes, whose GRWs are all optimal for fixed packet and code sizes but varying...... length are reducible codes up to rank equivalence; and 4) we show that the information leaked to a wire tapper when using reducible codes is often much less than the worst case given by their (optimal in some cases) GRWs. We conclude with some secondary related properties: conditions to be rank...

  16. Steam condensation modelling in aerosol codes

    International Nuclear Information System (INIS)

    Dunbar, I.H.

    1986-01-01

    The principal subject of this study is the modelling of the condensation of steam into and evaporation of water from aerosol particles. These processes introduce a new type of term into the equation for the development of the aerosol particle size distribution. This new term faces the code developer with three major problems: the physical modelling of the condensation/evaporation process, the discretisation of the new term and the separate accounting for the masses of the water and of the other components. This study has considered four codes which model the condensation of steam into and its evaporation from aerosol particles: AEROSYM-M (UK), AEROSOLS/B1 (France), NAUA (Federal Republic of Germany) and CONTAIN (USA). The modelling in the codes has been addressed under three headings. These are the physical modelling of condensation, the mathematics of the discretisation of the equations, and the methods for modelling the separate behaviour of different chemical components of the aerosol. The codes are least advanced in area of solute effect modelling. At present only AEROSOLS/B1 includes the effect. The effect is greater for more concentrated solutions. Codes without the effect will be more in error (underestimating the total airborne mass) the less condensation they predict. Data are needed on the water vapour pressure above concentrated solutions of the substances of interest (especially CsOH and CsI) if the extent to which aerosols retain water under superheated conditions is to be modelled. 15 refs

  17. A smart pill for drug delivery with sensing capabilities.

    Science.gov (United States)

    Goffredo, R; Accoto, D; Santonico, M; Pennazza, G; Guglielmelli, E

    2015-08-01

    In this paper a novel system for local drug delivery is described. The actuation principle of the micropump used for drug delivery relies on the electrolysis of a water-based solution, which is separated from a drug reservoir by an elastic membrane. The electrolytically produced gases pressurize the electrolytic solution reservoir, causing the deflection of the elastic membrane. Such deflection, in turn, forces the drug out of its reservoir through a nozzle. The proposed system is integrated in a swallowable capsule, equipped with an impedance sensor useful to acquire information on the physiological conditions of the tissue. Such information can be used to control pump activation.

  18. Implementation of data management and effect on chronic disease coding in a primary care organisation: A parallel cohort observational study.

    Science.gov (United States)

    Greiver, Michelle; Wintemute, Kimberly; Aliarzadeh, Babak; Martin, Ken; Khan, Shahriar; Jackson, Dave; Leggett, Jannet; Lambert-Lanning, Anita; Siu, Maggie

    2016-10-12

    Consistent and standardized coding for chronic conditions is associated with better care; however, coding may currently be limited in electronic medical records (EMRs) used in Canadian primary care.Objectives To implement data management activities in a community-based primary care organisation and to evaluate the effects on coding for chronic conditions. Fifty-nine family physicians in Toronto, Ontario, belonging to a single primary care organisation, participated in the study. The organisation implemented a central analytical data repository containing their EMR data extracted, cleaned, standardized and returned by the Canadian Primary Care Sentinel Surveillance Network (CPCSSN), a large validated primary care EMR-based database. They used reporting software provided by CPCSSN to identify selected chronic conditions and standardized codes were then added back to the EMR. We studied four chronic conditions (diabetes, hypertension, chronic obstructive pulmonary disease and dementia). We compared changes in coding over six months for physicians in the organisation with changes for 315 primary care physicians participating in CPCSSN across Canada. Chronic disease coding within the organisation increased significantly more than in other primary care sites. The adjusted difference in the increase of coding was 7.7% (95% confidence interval 7.1%-8.2%, p Data management activities were associated with an increase in standardized coding for chronic conditions. Exploring requirements to scale and spread this approach in Canadian primary care organisations may be worthwhile.

  19. TRANSDERMAL DRUG DELIVERY SYSTEM: REVIEW

    OpenAIRE

    Vishvakarama Prabhakar; Agarwal Shivendra; Sharma Ritika; Saurabh Sharma

    2012-01-01

    Various new technologies have been developed for the transdermal delivery of some important drugs. Today about 74% of drugs are taken orally and are found not to be as effective as desired. To improve such characters transdermal drug delivery system was emerged. Drug delivery through the skin to achieve a systemic effect of a drug is commonly known as transdermal drug delivery and differs from traditional topical drug delivery. Transdermal drug delivery systems (TDDS) are dosage forms involve...

  20. Transient heat transfer analysis up to dryout in 3D fuel rods under unideal conditions through the development of a computer code

    International Nuclear Information System (INIS)

    Martins, Rodolfo I.; Affonso, Renato R.W.; Moreira, Maria de Lourdes; Sampaio, Paulo A. B. de

    2017-01-01

    In this paper we analyze a conjugated transient heat transfer problem consisting of a nuclear reactor's fuel rod and its intrinsic coolant channel. Our analysis is made possible through a computer code being developed at the Instituto de Engenharia Nuclear (IEN/CNEN). This code is meant to study the temperature behavior in fuel rods which exhibit deviation from their ideal conditions, that is, rods in which the cladding is deformed or the fuel is dislocated. It is also designed to avoid the use of the computationally expensive Navier-Stokes equations. For these reasons, its physical model has as basis a three-dimensional fuel rod coupled to a one-dimensional coolant channel, which are discretized using the finite element method. Intending to study accidental conditions in which the coolant (light water) transcends its saturation temperature, turning into vapor, a homogeneous mixture is used to represent the two-phase flow, and so the coolant channel's energy equation is described using enthalpy. Owing to the fact that temperature and enthalpy are used in the physical model, it became impractical to generate a fully coupled method for solving the pertinent equations. Thus, the conjugated heat transfer problem is solved in a segregated manner through the implementation of an iterative method. Finally, as study cases for this paper we present analyses concerning the behavior of the hottest fuel rod in a Pressurized Water Reactor during a shutdown wherein the residual heat removal system is lost (loss of the reactor's coolant pumps). These studies contemplate cases in which the fuel rod's geometry is ideal or curved. Analyses are also performed for two circumstances of positioning of the fuel inside the rod: concentric and eccentric. (author)