WorldWideScience

Sample records for deficit reduction act

  1. Medicaid's Role in Financing Health Care for Children with Behavioral Health Care Needs in the Special Education System: Implications of the Deficit Reduction Act

    Science.gov (United States)

    Mandell, David S.; Machefsky, Aliza; Rubin, David; Feudtner, Chris; Pita, Susmita; Rosenbaum, Sara

    2008-01-01

    Background: Recent changes to Medicaid policy may have unintended consequences in the education system. This study estimated the potential financial impact of the Deficit Reduction Act (DRA) on school districts by calculating Medicaid-reimbursed behavioral health care expenditures for school-aged children in general and children in special…

  2. Medicaid’s Role in Financing Health Care for Children With Behavioral Health Care Needs in the Special Education System: Implications of the Deficit Reduction Act

    Science.gov (United States)

    Mandell, David S.; Machefsky, Aliza; Rubin, David; Feudtner, Chris; Pita, Susmita; Rosenbaum, Sara

    2010-01-01

    BACKGROUND Recent changes to Medicaid policy may have unintended consequences in the education system. This study estimated the potential financial impact of the Deficit Reduction Act (DRA) on school districts by calculating Medicaid-reimbursed behavioral health care expenditures for school-aged children in general and children in special education in particular. METHODS Medicaid claims and special education records of youth ages 6 to 18 years in Philadelphia, PA, were merged for calendar year 2002. Behavioral health care volume, type, and expenditures were compared between Medicaid-enrolled children receiving and not receiving special education. RESULTS Significant overlap existed among the 126,533 children who were either Medicaid enrolled (114,257) or received special education (27,620). Medicaid-reimbursed behavioral health care was used by 21% of children receiving special education (37% of those Medicaid enrolled) and 15% of other Medicaid-enrolled children. Total expenditures were $197.8 million, 40% of which was spent on the 5728 children in special education and 60% of which was spent on 15,092 other children. CONCLUSIONS Medicaid-reimbursed behavioral health services disproportionately support special education students, with expenditures equivalent to 4% of Philadelphia’s $2 billion education budget. The results suggest that special education programs depend on Medicaid-reimbursed services, the financing of which the DRA may jeopardize. PMID:18808472

  3. 26 CFR 301.9100-6T - Time and manner of making certain elections under the Deficit Reduction Act of 1984.

    Science.gov (United States)

    2010-04-01

    ... for alcohol used as fuel. The election under section 40(f) (as added by section 474(k) of the Act) not... election under such section 102(d)(3), guidelines for making such an election are not provided in this...

  4. Marine Debris Research, Prevention, and Reduction Act

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Marine Debris Research, Prevention, and Reduction Act legally establishes the National Oceanic and Atmospheric Administration's (NOAA) Marine Debris Program. The...

  5. Accuracy, precision, and lower detection limits (a deficit reduction approach)

    International Nuclear Information System (INIS)

    Bishop, C.T.

    1993-01-01

    The evaluation of the accuracy, precision and lower detection limits of the determination of trace radionuclides in environmental samples can become quite sophisticated and time consuming. This in turn could add significant cost to the analyses being performed. In the present method, a open-quotes deficit reduction approachclose quotes has been taken to keep costs low, but at the same time provide defensible data. In order to measure the accuracy of a particular method, reference samples are measured over the time period that the actual samples are being analyzed. Using a Lotus spreadsheet, data are compiled and an average accuracy is computed. If pairs of reference samples are analyzed, then precision can also be evaluated from the duplicate data sets. The standard deviation can be calculated if the reference concentrations of the duplicates are all in the same general range. Laboratory blanks are used to estimate the lower detection limits. The lower detection limit is calculated as 4.65 times the standard deviation of a set of blank determinations made over a given period of time. A Lotus spreadsheet is again used to compile data and LDLs over different periods of time can be compared

  6. 77 FR 6803 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-02-09

    ... pregnant during Health Questionnaire/ 750 1 20/60 NHANES 1999-2010. Consent Form. 3. State/local vital...-11CE] Agency Forms Undergoing Paperwork Reduction Act Review The Centers for Disease Control and... about the pregnant women at the time of interview. Having information on their children's birth...

  7. 77 FR 37051 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-06-20

    ... Year 1 and Year 2. Informed Consent Form... 4,404 1 2/60 Non-Responder Interview. 792 1 5/60 Kimberly S...] Agency Forms Undergoing Paperwork Reduction Act Review The Centers for Disease Control and Prevention...-minute interview will be conducted with a 10% sample of non-responders (up to 792 individuals). In order...

  8. 75 FR 68360 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-11-05

    ...] Agency Forms Undergoing Paperwork Reduction Act Review The Centers for Disease Control and Prevention... screener questionnaire will be used to determine participation eligibility and obtain oral consent. Approximately 7,000 individuals will be approached and screened (through a 2-minute interview) for eligibility...

  9. 75 FR 6671 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-02-10

    ... programs implemented a new consent form. This form asked participants for permission for CDC to contact...] Agency Forms Undergoing Paperwork Reduction Act Review The Centers for Disease Control and Prevention... prevention behaviors, CDC will conduct telephone interviews of 425 Matter of Balance program participants six...

  10. 75 FR 24706 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-05-05

    ... parent consent 214 1 10/60 form. Child Clinic Visit--Case 107 1 1.5 children packet. Parent Clinic Visit...] Agency Forms Undergoing Paperwork Reduction Act Review The Centers for Disease Control and Prevention...; (4) a telephone interview focusing on pregnancy-related events and early life history (biological...

  11. 76 FR 38654 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-07-01

    ... consent for an interview. After the data collection phase, a multidisciplinary case review team (CRT) will... Post-Partum HIV- FIMR/HIV Maternal 300 1 1.5 infected Women. Interview Form. Daniel L. Holcomb, Reports...] Agency Forms Undergoing Paperwork Reduction Act Review The Centers for Disease Control and Prevention...

  12. 77 FR 12594 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-03-01

    ... Script. Refusal Questions Form.. 62 1 2/60 Individual Consent Form. 250 1 3/60 Contact Information Form... Screening 92 1 5/60 Survey. Informed Consent........ 50 1 1/60 Interview Questionnaire. 50 1 1 Network Size...-12-12BL] Agency Forms Undergoing Paperwork Reduction Act Review The Agency for Toxic Substances and...

  13. 76 FR 55915 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-09-09

    ... type 2 diabetes DPRP Application Form........ 120 1 1 prevention programs. DPRP Evaluation Data... mechanism for recognizing organizations that deliver effective, community-based type 2 diabetes prevention...] Agency Forms Undergoing Paperwork Reduction Act Review The Centers for Disease Control and Prevention...

  14. 76 FR 5377 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-01-31

    ... Budget (OMB) in compliance with the Paperwork Reduction Act (44 U.S.C. Chapter 35). To request a copy of... Project Developing a Sexual Consent Norms Instrument--New--National Center for Injury Prevention and... violence prevention strategies are increasingly focusing on promoting positive behavioral norms such as...

  15. 75 FR 37445 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-06-29

    ... Budget (OMB) in compliance with the Paperwork Reduction Act (44 U.S.C. Chapter 35). To request a copy of... HIV testing, socio-cultural norms, and perceived behavioral control factors that influence HIV testing... identify variables for a survey that will examine attitudes towards HIV testing, socio-cultural norms, and...

  16. 76 FR 24537 - Paperwork Reduction Act; Proposed Collection; Comment Request

    Science.gov (United States)

    2011-05-02

    ... President, Office of National Drug Control Policy, Drug-Free Communities (DFC) Support Program, 750 17th... OFFICE OF NATIONAL DRUG CONTROL POLICY Paperwork Reduction Act; Proposed Collection; Comment Request AGENCY: Office of National Drug Control Policy. ACTION: 60-Day notice and request for comments...

  17. 75 FR 65489 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-10-25

    ... children. The three environmental chemicals, Bisphenol A (BPA), phthalates, and mercury have been selected...] Agency Forms Undergoing Paperwork Reduction Act Review The Centers for Disease Control and Prevention (CDC) publishes a list of information collection requests under review by the Office of Management and...

  18. 77 FR 76045 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-12-26

    ... case classification (disease staging system). Recommendations for revisions in the case definition were... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention [30Day-13-0573] Agency Forms Undergoing Paperwork Reduction Act Review The Centers for Disease Control and Prevention...

  19. 78 FR 9699 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-02-11

    ... Budget (OMB) in compliance with the Paperwork Reduction Act (44 U.S.C. Chapter 35). To request a copy of... Officer, Office of Management and Budget, Washington, DC 20503 or by fax to (202) 395-5806. Written... through advertisements in laboratory trade publications, at professional meetings, and possibly through...

  20. 75 FR 25859 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-05-10

    ... drinking water will also be examined: Parkinson's disease, kidney failure and other severe kidney diseases... Budget (OMB) in compliance with the Paperwork Reduction Act (44 U.S.C. Chapter 35). To request a copy of... comparison group. As required by law, health surveys will also be mailed to those who registered with the...

  1. 77 FR 40363 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-07-09

    ... Methicillin-resistant Staphylococcus aureus (MRSA) among Patients Recently Discharged from Acute Care... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention [30-Day-12-12II] Agency Forms Undergoing Paperwork Reduction Act Review The Centers for Disease Control and Prevention...

  2. 78 FR 40151 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-07-03

    ... resistant Staphylococcus aureus ABCs Case Report Form. ABCs Invasive Pneumococcal 10 41 10/60 Disease in... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention [30-Day 13-13DB] Agency Forms Undergoing Paperwork Reduction Act Review The Centers for Disease Control and Prevention...

  3. 75 FR 20601 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-04-20

    .... Proposed Project Asthma Information Reporting System (AIRS)--New--Air Pollution and Respiratory Health... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention [30Day-10-09CK] Agency Forms Undergoing Paperwork Reduction Act Review The Centers for Disease Control and prevention...

  4. 78 FR 24422 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-04-25

    ... System (AIRS) (0920-0853, Expiration 06/30/2013)--Extension--Air Pollution and Respiratory Health Branch... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention [30Day-13-0853] Agency Forms Undergoing Paperwork Reduction Act Review The Centers for Disease Control and Prevention...

  5. Tau reduction diminishes spatial learning and memory deficits after mild repetitive traumatic brain injury in mice.

    Directory of Open Access Journals (Sweden)

    Jason S Cheng

    Full Text Available OBJECTIVE: Because reduction of the microtubule-associated protein Tau has beneficial effects in mouse models of Alzheimer's disease and epilepsy, we wanted to determine whether this strategy can also improve the outcome of mild traumatic brain injury (TBI. METHODS: We adapted a mild frontal impact model of TBI for wildtype C57Bl/6J mice and characterized the behavioral deficits it causes in these animals. The Barnes maze, Y maze, contextual and cued fear conditioning, elevated plus maze, open field, balance beam, and forced swim test were used to assess different behavioral functions. Magnetic resonance imaging (MRI, 7 Tesla and histological analysis of brain sections were used to look for neuropathological alterations. We also compared the functional effects of this TBI model and of controlled cortical impact in mice with two, one or no Tau alleles. RESULTS: Repeated (2-hit, but not single (1-hit, mild frontal impact impaired spatial learning and memory in wildtype mice as determined by testing of mice in the Barnes maze one month after the injury. Locomotor activity, anxiety, depression and fear related behaviors did not differ between injured and sham-injured mice. MRI imaging did not reveal focal injury or mass lesions shortly after the injury. Complete ablation or partial reduction of tau prevented deficits in spatial learning and memory after repeated mild frontal impact. Complete tau ablation also showed a trend towards protection after a single controlled cortical impact. Complete or partial reduction of tau also reduced the level of axonopathy in the corpus callosum after repeated mild frontal impact. INTERPRETATION: Tau promotes or enables the development of learning and memory deficits and of axonopathy after mild TBI, and tau reduction counteracts these adverse effects.

  6. 77 FR 4044 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-01-26

    ... and ethnic minorities. Priority areas for the program include breast and cervical cancer..., deficits in breast and cervical cancer screening and management, and deficits in adult immunizations... factor surveys that tracked health trends among racial and ethnic minority groups (OMB No. 0920-0805, exp...

  7. The use of cold porcelain orthoses to implement the act of playing of a child with motor deficit

    Directory of Open Access Journals (Sweden)

    Marilda Ferraz Santana

    2012-06-01

    Full Text Available playing of the child with motor deficit. Methods: Applied research, quantitative and qualitative, in the Center for Integrated Healthcare (NAMI in Fortaleza - CE, Brazil. The investigation occurred in the period from February to June 2008. Sample of 22 children, 14 selected in the survey entitled “Reduction in costs for making orthoses” and 8 indicated by professionals. We applied semi-structured interviews with officials, evaluate the play behavior based on the Protocol of Ferland. In the analysis of qualitative information, we used Bardin’s Content Analysis. For quantitative data, we used the statistical treatment of Morettin. Results: The qualitative categories were organized into three: the parents’ opinion about the act of playing of their children, type of toy and improvement in occupationalperformance with the use of orthosis. The quantitative analysis allowed the consolidation of data in tables, after the Behavior Assessment Playful, applied in the beginning and in the end of the study. Conclusions: This study showed, therefore, that the use of “cold porcelain” orthoses interfered, overwhelmingly, both in performing of the act of playing of the children who participated in this research, as well as in occupational performance in various areas, passing by significant changes, bringing value also in the interest, ability to perform an activity and relationships and feelings.

  8. Fluoxetine prevents the memory deficits and reduction in hippocampal cell proliferation caused by valproic acid.

    Science.gov (United States)

    Welbat, Jariya Umka; Sangrich, Preeyanuch; Sirichoat, Apiwat; Chaisawang, Pornthip; Chaijaroonkhanarak, Wunnee; Prachaney, Parichat; Pannangrong, Wanassanun; Wigmore, Peter

    2016-12-01

    Valproic acid (VPA), a commonly used antiepileptic drug, has been reported to cause cognitive impairments in patients. In a previous study, using a rodent model, we showed that VPA treatment impaired cognition which was associated with a reduction in the cell proliferation required for hippocampal neurogenesis. The antidepressant fluoxetine has been shown to increase hippocampal neurogenesis and to reverse the memory deficits found in a number of pathological conditions. In the present study we investigated the protective effects of fluoxetine treatment against the impairments in memory and hippocampal cell proliferation produced by VPA. Male Sprague Dawley rats received daily treatment with fluoxetine (10mg/kg) by oral gavage for 21days. Some rats were co-administered with VPA (300mg/kg, twice daily i.p. injections) for 14days from day 8 to day 21 of the fluoxetine treatment. Spatial memory was tested using the novel object location (NOL) test. The number of proliferating cells present in the sub granular zone of the dentate gyrus was quantified using Ki67 immunohistochemistry at the end of the experiment. Levels of the receptor Notch1, the neurotrophic factor BDNF and the neural differentiation marker DCX were determined by Western blotting. VPA-treated rats showed memory deficits, a decrease in the number of proliferating cells in the sub granular zone and decreases in the levels of Notch1 and BDNF but not DCX compared to control animals. These changes in behavior, cell proliferation and Notch1 and BDNF were prevented in animals which had received both VPA and fluoxetine. Rats receiving fluoxetine alone did not show a significant difference in the number of proliferating cells or behavior compared to controls. These results demonstrated that the spatial memory deficits and reduction of cell proliferation produced by VPA can be ameliorated by the simultaneous administration of the antidepressant fluoxetine. Crown Copyright © 2016. Published by Elsevier B

  9. 78 FR 35272 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-06-12

    ...); sickle cell disease (SCD); attention-deficit/hyperactivity disorder (ADHD); and Tourette syndrome. Birth... blood disorders. Identified priority diseases, disorders, and conditions included in this information collection activity include but are not limited to preconception health; autism spectrum disorders (ASDs) and...

  10. 75 FR 6205 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-02-08

    ...-Child Relationship 190 1 15/60 Inventory. Parent Parents' Mental Health 178 1 5/60 Questionnaire. Parent..., Washington, DC or by fax to (202) 395-5806. Written comments should be received within 30 days of this notice. Proposed Project Longitudinal follow-up of Youth with Attention-Deficit/ Hyperactivity Disorder identified...

  11. 77 FR 49797 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-08-17

    ... social marketing campaigns under the umbrella of the larger Act Against AIDS campaign. The target... Project Formative Research for the Development of CDC's Act Against AIDS Social Marketing Campaigns... period to develop various social marketing campaigns aimed at increasing HIV testing rates, increasing...

  12. Transpedicular hydroxyapatite grafting with indirect reduction for thoracolumbar burst fractures with neurological deficit: A prospective study

    Directory of Open Access Journals (Sweden)

    Toyone Tomoaki

    2007-01-01

    Full Text Available Background: The major problem after posterior correction and instrumentation in the treatment of thoracolumbar burst fractures is failure to support the anterior spinal column leading to loss of correction of kyphosis and hardware breakage. We conducted a prospective consecutive series to evaluate the outcome of the management of acute thoracolumbar burst fractures by transpedicular hydroxyapatite (HA grafting following indirect reduction and pedicle screw fixation. Materials and Methods: Eighteen consecutive patients who had thoracolumbar burst fractures and associated incomplete neurological deficit, operatively treated within four days of admission. Following indirect reduction and pedicle screw fixation, transpedicular intracorporeal HA grafting to the fractured vertebrae was performed. Mean operative time was 125 min and mean blood loss was 150 ml. Their implants were removed within one year and were prospectively followed for at least two years. Results: The neurological function of all 18 patients improved by at least one ASIA grade, with nine (50% patients demonstrating complete neurological recovery. Sagittal alignment was improved from a mean preoperative kyphosis of 17°to -2°(lordosis by operation, but was found to have slightly deteriorated to 1° at final follow-up observation. The CT images demonstrated a mean spinal canal narrowing pre-operatively immediate post-operative and at final followup of 60%, 22% and 11%, respectively . There were no instances of hardware failure. No patient reported severe pain or needed daily dosages of analgesics at the final follow-up. The two-year postoperative MRI demonstrated an increase of one grade in disc degeneration (n = 17 at the disc above and in 11 patients below the fractured vertebra. At the final follow-up, flexion-extension radiographs revealed that a median range of motion was 4, 6 and 34 degrees at the cranial segment of the fractured vertebra, caudal segment and L1-S1, respectively

  13. 75 FR 17410 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-04-06

    ... for Occupational Safety and Health (NIOSH), Centers for Disease Control and Prevention (CDC). [[Page... Health Act, the National Institute for Occupational Safety and Health (NIOSH) has been at the forefront..., NIOSH employs engineers and scientists with experience and expertise in mine safety and health issues...

  14. 75 FR 70929 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-11-19

    ... national anti-terrorism policies and assigned specific missions to federal departments and agencies. The... respond to acts of biological, chemical, or radiological terrorism and other public health emergencies... equipment inventories. The collection of personal identifiable information for the purpose of communication...

  15. 77 FR 70781 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-11-27

    ... comments should be received within 30 days of this notice. Proposed Project Workplace Violence Prevention... prevention programs. However, little is understood about how effective these laws are in reducing violence... facility compliance with the New Jersey Violence Prevention in Health Care Facilities Act, (2) to evaluate...

  16. 77 FR 51807 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-08-27

    ... Cervical Cancer Mortality Prevention Act of 1990. Screening services include clinical breast examinations... Minimum Data Elements (MDEs) for the National Breast and Cervical Cancer Early Detection Program (NBCCEDP... screening and early detection tests for breast and cervical cancer. Mammography is extremely valuable as an...

  17. 76 FR 70729 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-11-15

    ... each of the four grantees. The surveys will capture information from the program's target audience to... Evaluation of Enhanced Implementation of the ``Learn the Signs. Act Early.'' Campaign in 4 Target Sites,--New... effectively reaching the target populations. The evaluation will be accomplished by a pre-implementation...

  18. 78 FR 14554 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-03-06

    ... will focus on specific subpopulations at greatest risk for HIV infection. The target audiences will... Project Formative Research for the Development of CDC's Act Against AIDS Social Marketing Campaigns... period to develop various social marketing campaigns aimed at increasing HIV testing rates, increasing...

  19. 76 FR 23818 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-04-28

    ... Project Evaluating Act Against AIDS Social Marketing Campaign Phases Targeting Consumers--New--National... concurrently. Each phase of the campaign will use mass media and direct-to-consumer channels to deliver HIV... effectiveness of these social marketing messages aimed at increasing HIV awareness and delivering HIV prevention...

  20. 78 FR 35635 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-06-13

    ... the cognitive demands that affect a miner's ability to do his or her job. To be consistent with... Systems Integration Needs in Mining--New--National Institute for Occupational Safety and Health (NIOSH... 91-173 as amended by Public Law 95-164 (Federal Mine Safety and Health Act of 1977), and Public Law...

  1. 78 FR 307 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-01-03

    ... (CDC) publishes a list of information collection requests under review by the Office of Management and.../AIDS Strategic Plan. (3) reporting has been changed from quarterly to semiannual. (4) the number of... how these efforts have contributed to a reduction in HIV transmission; (2) improve ease of reporting...

  2. 46 CFR 147.8 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Science.gov (United States)

    2010-10-01

    ...) DANGEROUS CARGOES HAZARDOUS SHIPS' STORES General Provisions § 147.8 OMB control numbers assigned pursuant... Management and Budget (OMB) pursuant to the Paperwork Reduction Act of 1980 (44 U.S.C. 3501 et seq.). The...

  3. Growth deficits in cystic fibrosis mice begin in utero prior to IGF-1 reduction.

    Directory of Open Access Journals (Sweden)

    Rebecca Darrah

    Full Text Available Growth deficits are common in cystic fibrosis (CF, but their cause is complex, with contributions from exocrine pancreatic insufficiency, pulmonary complications, gastrointestinal obstructions, and endocrine abnormalities. The CF mouse model displays similar growth impairment despite exocrine pancreatic function and in the absence of chronic pulmonary infection. The high incidence of intestinal obstruction in the CF mouse has been suggested to significantly contribute to the observed growth deficits. Previous studies by our group have shown that restoration of the cystic fibrosis transmembrane conductance regulator (CFTR in the intestinal epithelium prevents intestinal obstruction but does not improve growth. In this study, we further investigate growth deficits in CF and gut-corrected CF mice by assessing insulin-like growth factor 1 (IGF-1. IGF-1 levels were significantly decreased in CF and gut-corrected CF adult mice compared to wildtype littermates and were highly correlated with weight. Interestingly, perinatal IGF-1 levels were not significantly different between CF and wildtype littermates, even though growth deficits in CF mice could be detected late in gestation. Since CFTR has been suggested to play a role in water and nutrient exchange in the placenta through its interaction with aquaporins, we analyzed placental aquaporin expression in late-gestation CF and control littermates. While significant differences were observed in Aquaporin 9 expression in CF placentas in late gestation, there was no evidence of placental fluid exchange differences between CF and control littermates. The results from this study indicate that decreased IGF-1 levels are highly correlated with growth in CF mice, independent of CF intestinal obstruction. However, the perinatal growth deficits that are observed in CF mice are not due to decreased IGF-1 levels or differences in placenta-mediated fluid exchange. Further investigation is necessary to understand

  4. Innovative Management of Budget Deficits: A Proportional Salary and Time Reduction Scheme.

    Science.gov (United States)

    Sloper, David

    1989-01-01

    An approach to institutional budgeting designed to alleviate accumulated deficits is described. The proposal introduces flexibility into the salary component, alleviating cash flow difficulties in the short to medium term and encouraging more proactive budgeting, by allowing employees to contract for reduced annual salary in exchange for reduced…

  5. Developmentally Stable Whole-Brain Volume Reductions and Developmentally Sensitive Caudate and Putamen Volume Alterations in Those With Attention-Deficit/Hyperactivity Disorder and Their Unaffected Siblings

    NARCIS (Netherlands)

    Greven, Corina U.; Bralten, Janita; Mennes, Maarten; O'Dwyer, Laurence; van Hulzen, Kimm J. E.; Rommelse, Nanda; Schweren, Lizanne J. S.; Hoekstra, Pieter J.; Hartman, Catharina A.; Heslenfeld, Dirk; Oosterlaan, Jaap; Faraone, Stephen V.; Franke, Barbara; Zwiers, Marcel P.; Arias-Vasquez, Alejandro; Buitelaar, Jan K.

    IMPORTANCE Attention-deficit/hyperactivity disorder (ADHD) is a heritable neurodevelopmental disorder. It has been linked to reductions in total brain volume and subcortical abnormalities. However, owing to heterogeneity within and between studies and limited sample sizes, findings on the

  6. Financial effect of instituting Deficit Reduction Act documentation requirements in family planning clinics in Oregon.

    Science.gov (United States)

    Rodriguez, Maria Isabel; Angus, Lisa; Elman, Emily; Darney, Philip D; Caughey, Aaron B

    2011-06-01

    The study was conducted to estimate the long-term costs for implementing citizenship documentation requirements in a Medicaid expansion program for family planning services in Oregon. A decision-analytic model was developed using two perspectives: the state and society. Our primary outcome was future reproductive health care costs due to pregnancy in the next 5 years. A Markov structure was utilized to capture multiple future pregnancies. Model inputs were retrieved from the existing literature and local hospital and Medicaid data related to reimbursements. One-way and multi-way sensitivity analyses were conducted. A Monte Carlo simulation was performed to simultaneously incorporate uncertainty from all of the model inputs. Screening for citizenship results in a loss of $3119 over 5 years ($39,382 vs. $42,501) for the state and $4209 for society ($63,391 compared to $59,182) for adult women. Among adolescents, requiring proof of identity and citizenship results in a loss of $3123 for the state ($39,378 versus $42,501) and $4214 for society ($63,391 instead of $59,177). Screening for citizenship status in publicly funded family planning clinics leads to financial losses for the state and society. Copyright © 2011 Elsevier Inc. All rights reserved.

  7. 48 CFR 301.106 - Office of Management and Budget approval under the Paperwork Reduction Act.

    Science.gov (United States)

    2010-10-01

    ... Issuance 301.106 Office of Management and Budget approval under the Paperwork Reduction Act. (a) The... approval from the Office of Management and Budget (OMB) before collecting the same information from 10 or... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Office of Management and...

  8. 46 CFR 159.001-9 - OMB Control Numbers assigned pursuant to the Paperwork Reduction Act.

    Science.gov (United States)

    2010-10-01

    .... This section collects and displays the control numbers assigned to information collection and... Paperwork Reduction Act of 1980, (44 U.S.C. 3501 et seq.). The Coast Guard intends that this section comply with the requirements of 44 U.S.C. 3507(f) which requires that agencies display a current control...

  9. 15 CFR 806.18 - OMB control numbers assigned to the Paperwork Reduction Act.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false OMB control numbers assigned to the Paperwork Reduction Act. 806.18 Section 806.18 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF ECONOMIC ANALYSIS, DEPARTMENT OF COMMERCE DIRECT INVESTMENT...

  10. 7 CFR 1425.24 - OMB control number assigned pursuant to Paperwork Reduction Act.

    Science.gov (United States)

    2010-01-01

    ...) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS COOPERATIVE MARKETING ASSOCIATIONS § 1425.24 OMB control number assigned pursuant to Paperwork Reduction Act. The... Office of Management and Budget (OMB) under the provisions of 44 U.S.C. Chapter 35 and have been assigned...

  11. Projects to Improve Air Quality at Ports – 2014 Diesel Emissions Reduction Act (DERA) Funding Opportunity - Closed Announcement FY 2014

    Science.gov (United States)

    OTAQ is soliciting proposals that achieve reductions in diesel emissions produced by diesel engines and diesel emissions exposure, from fleets operating at marine and inland water ports under the Diesel Emissions Reduction Act (DERA).

  12. Projects to Improve Air Quality at Ports – 2013 Diesel Emissions Reduction Act (DERA) Funding Opportunity - Closed Announcement FY 2014

    Science.gov (United States)

    OTAQ is soliciting proposals that achieve reductions in diesel emissions produced by diesel engines and diesel emissions exposure, from fleets operating at marine and inland water ports under the Diesel Emissions Reduction Act (DERA).

  13. [Attention deficit and understanding of non-literal meanings: the interpretation of indirect speech acts and idioms].

    Science.gov (United States)

    Crespo, N; Manghi, D; García, G; Cáceres, P

    To report on the oral comprehension of the non-literal meanings of indirect speech acts and idioms in everyday speech by children with attention deficit hyperactivity disorder (ADHD). The subjects in this study consisted of a sample of 29 Chilean schoolchildren aged between 6 and 13 with ADHD and a control group of children without ADHD sharing similar socio-demographic characteristics. A quantitative method was utilised: comprehension was measured individually by means of an interactive instrument. The children listened to a dialogue taken from a cartoon series that included indirect speech acts and idioms and they had to choose one of the three options they were given: literal, non-literal or distracter. The children without ADHD identified the non-literal meaning more often, especially in idioms. Likewise, it should be pointed out that whereas the children without ADHD increased their scores as their ages went up, those with ADHD remained at the same point. ADHD not only interferes in the inferential comprehension of non-literal meanings but also inhibits the development of this skill in subjects affected by it.

  14. 14 CFR 11.201 - Office of Management and Budget (OMB) control numbers assigned under the Paperwork Reduction Act.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Office of Management and Budget (OMB) control numbers assigned under the Paperwork Reduction Act. 11.201 Section 11.201 Aeronautics and Space... PROCEDURES Paperwork Reduction Act Control Numbers § 11.201 Office of Management and Budget (OMB) control...

  15. A Comparison of Effectiveness of Parent Behavioral Management Training and Methylphenidate on Reduction of Symptomsof Attention Deficit Hyperactivity Disorder

    Directory of Open Access Journals (Sweden)

    Mohammad Reza Mohammadi

    2016-09-01

    Full Text Available Attention deficit hyperactivity disorder (ADHD is one of the most common psychological disorders of childhood. Methylphenidate is highly effective in the treatment of ADHD. This study aimed to determine the effectiveness of combined Parent behavioral management training (PBMT and medication treatment (Methylphenidate in reducing ADHD symptoms in 6-12-year-old children, using randomized sampling. A total of 50 children with ADHD were assigned into two groups: an experimental group of PBMT and a control group of medication treatment (Methylphenidate without other interventions. Conners’ Parent Rating Scale (CPRS-48 was employed before and after interventions to determine the effects. Descriptive Statistics method (consisting of Mean and Standard deviation and Statistical inference method, (including t-test and Levene's Test were used for data analysis.  Findings revealed that the combined behavioral intervention of PBMT and methylphenidate treatment is more effective in reduction of ADHD in children. The difference of means between pre-test and post-test of CPRS in the experimental group was equal to 10.77, and it was equal to 1.88 in the control group. In addition, PBMT was more effective in the case of younger parents (P<0.025. However, parents’ education level did not affect the behavioral intervention (P<0.025.The findings suggest that combined intervention of PBMT and methylphenidate is effective in reducing the symptoms of ADHD in children.

  16. The Massachusetts Toxics Use Reduction Act: a model for nanomaterials regulation?

    Science.gov (United States)

    Nash, Jennifer

    2012-08-01

    Nanomaterials exemplify a new class of emerging technologies that have significant economic and social value, pose uncertain health and environmental risks, and are entering the marketplace at a rapid pace. Effective regimes for regulating emerging technologies generate information about known or suspected hazards and draw on private sector expertise to guide managers' behavior toward risk reduction, even in the absence of clear evidence of harm. This paper considers the extent to which the federal Toxic Substances Control Act (TSCA) accomplishes those objectives. It offers the approach of the Massachusetts Toxics Use Reduction Act (TURA) as a possible supplement to TSCA, filling gaps in agency knowledge and private sector capacities. TURA is notable for its focus on chemicals use and hazard and its emphasis on strengthening firms' internal management systems. Given the current deadlock in Congressional efforts to modernize federal laws such as TSCA, the role of state laws like TURA merit attention. Absent definitive information about risk, a governance strategy that generates information and focuses management attention on reducing hazards is worth considering.

  17. The Massachusetts Toxics Use Reduction Act: a model for nanomaterials regulation?

    International Nuclear Information System (INIS)

    Nash, Jennifer

    2012-01-01

    Nanomaterials exemplify a new class of emerging technologies that have significant economic and social value, pose uncertain health and environmental risks, and are entering the marketplace at a rapid pace. Effective regimes for regulating emerging technologies generate information about known or suspected hazards and draw on private sector expertise to guide managers’ behavior toward risk reduction, even in the absence of clear evidence of harm. This paper considers the extent to which the federal Toxic Substances Control Act (TSCA) accomplishes those objectives. It offers the approach of the Massachusetts Toxics Use Reduction Act (TURA) as a possible supplement to TSCA, filling gaps in agency knowledge and private sector capacities. TURA is notable for its focus on chemicals use and hazard and its emphasis on strengthening firms’ internal management systems. Given the current deadlock in Congressional efforts to modernize federal laws such as TSCA, the role of state laws like TURA merit attention. Absent definitive information about risk, a governance strategy that generates information and focuses management attention on reducing hazards is worth considering.

  18. Pharmacokinetic variability of long-acting stimulants in the treatment of children and adults with attention-deficit hyperactivity disorder.

    Science.gov (United States)

    Ermer, James C; Adeyi, Ben A; Pucci, Michael L

    2010-12-01

    Methylphenidate- and amfetamine-based stimulants are first-line pharmacotherapies for attention-deficit hyperactivity disorder, a common neurobehavioural disorder in children and adults. A number of long-acting stimulant formulations have been developed with the aim of providing once-daily dosing, employing various means to extend duration of action, including a transdermal delivery system, an osmotic-release oral system, capsules with a mixture of immediate- and delayed-release beads, and prodrug technology. Coefficients of variance of pharmacokinetic measures can estimate the levels of pharmacokinetic variability based on the measurable variance between different individuals receiving the same dose of stimulant (interindividual variability) and within the same individual over multiple administrations (intraindividual variability). Differences in formulation clearly impact pharmacokinetic profiles. Many medications exhibit wide interindividual variability in clinical response. Stimulants with low levels of inter- and intraindividual variability may be better suited to provide consistent levels of medication to patients. The pharmacokinetic profile of stimulants using pH-dependent bead technology can vary depending on food consumption or concomitant administration of medications that alter gastric pH. While delivery of methylphenidate with the transdermal delivery system would be unaffected by gastrointestinal factors, intersubject variability is nonetheless substantial. Unlike the beaded formulations and, to some extent (when considering total exposure) the osmotic-release formulation, systemic exposure to amfetamine with the prodrug stimulant lisdexamfetamine dimesylate appears largely unaffected by such factors, likely owing to its dependence on systemic enzymatic cleavage of the precursor molecule, which occurs primarily in the blood involving red blood cells. The high capacity but as yet unidentified enzymatic system for conversion of lisdexamfetamine

  19. ADD-H-Comprehensive Teacher's Rating Scale (ACTeRS): a measure for attention deficit hyperactivity disorder among children with intellectual disability in India.

    Science.gov (United States)

    Tsheringla, Sherab; Simon, Aby; Russell, Paul Swamidhas Sudhakar; Shankar, SatyaRaj; Russell, Sushila; Mammen, Priya; Nair, M K C

    2014-12-01

    There is no validated measure for assessing Attention Deficit Hyperactivity Disorder (ADHD) in India, and therefore, the authors validated the ADD-H Comprehensive Teacher's Rating Scale (ACTeRS). Teachers/parents/clinicians of 110 children with ADHD completed the ACTeRS. The diagnosis of ADHD was confirmed by an independent multi-disciplinary team using ICD-10 diagnosis for diagnostic accuracy and criterion validity. The convergent and divergent validity were assessed by another rater. The data was analyzed for diagnostic accuracy, reliability and validity appropriately. An ACTeRS score of ≥61 [Sensitivity (Sn) =85.51%; Specificity (Sp) = 90.24%; Area under the curve (AUC) = 0.94] is appropriate for the diagnosis of ADHD. The test-re-test reliability [Intra-class correlation coefficient (ICC) = 0.87], internal consistency (Cronbach's α = 0.80; range of 0.89-0.93), section-total correlation, face and content validity for the ACTeRS were good. Convergent validity of attention deficit, hyperactivity and oppositional subscales of ACTeRS with the corresponding subscales of Swanson, Nolan & Pelham Rating Scale-Revised (SNAP-IV) was moderate (r = 0.60, P = 0.005; r = 0.49, P = 0.02; r = 0.58, P = 0.008 respectively), and negative correlation with the Childhood Autism Rating Scale (r = -0.36; P =0.1) for divergent validity was found. The criterion validity analysis showed a high concordance rate of 82.52% between ACTeRS and International Classification of Diseases, Edition10 (ICD-10) diagnosis of ADHD. A 4-factor structure was replicated. The ACTeRS has adequate psychometric properties for use in the Indian population for identifying ADHD.

  20. Functional improvement and correlations with symptomatic improvement in adults with attention deficit hyperactivity disorder receiving long-acting methylphenidate.

    NARCIS (Netherlands)

    Buitelaar, J.K.; Casas, M.; Philipsen, A.; Kooij, J.J.; Ramos-Quiroga, J.A.; Dejonckheere, J.; Oene, J.C. van; Schauble, B.

    2012-01-01

    BACKGROUND: Data on the relationship between core symptoms and daily functioning in adults with attention deficit hyperactivity disorder (ADHD) are limited. Daily functioning was assessed as part of an open-label extension, and associations with symptom scores were evaluated. METHOD: After a 5-week

  1. 7 CFR 62.400 - OMB control number assigned pursuant to the Paperwork Reduction Act.

    Science.gov (United States)

    2010-01-01

    ...) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 AND THE EGG PRODUCTS INSPECTION ACT (CONTINUED) LIVESTOCK, MEAT, AND OTHER AGRICULTURAL COMMODITIES (QUALITY SYSTEMS VERIFICATION...

  2. 15 CFR 30.63 - Office of Management and Budget control numbers assigned pursuant to the Paperwork Reduction Act.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Office of Management and Budget control numbers assigned pursuant to the Paperwork Reduction Act. 30.63 Section 30.63 Commerce and Foreign... FOREIGN TRADE REGULATIONS General Administrative Provisions § 30.63 Office of Management and Budget...

  3. 78 FR 44188 - Paperwork Reduction Act of 1995, as Amended by Public Law 104-13; Proposed Collection, Comment...

    Science.gov (United States)

    2013-07-23

    ... TENNESSEE VALLEY AUTHORITY Paperwork Reduction Act of 1995, as Amended by Public Law 104-13; Proposed Collection, Comment Request AGENCY: Tennessee Valley Authority. ACTION: Proposed Collection... preference. The information is used to make comparative appraisals and to assist in selections. The affected...

  4. 75 FR 27863 - Paperwork Reduction Act of 1995, as Amended by Public Law 104-13; Proposed Collection, Comment...

    Science.gov (United States)

    2010-05-18

    ... TENNESSEE VALLEY AUTHORITY Paperwork Reduction Act of 1995, as Amended by Public Law 104-13; Proposed Collection, Comment Request AGENCY: Tennessee Valley Authority. ACTION: Proposed collection... preference. The information is used to make comparative appraisals and to assist in selections. The affected...

  5. Association of a carboxylesterase 1 polymorphism with appetite reduction in children and adolescents with attention-deficit/hyperactivity disorder treated with methylphenidate.

    Science.gov (United States)

    Bruxel, E M; Salatino-Oliveira, A; Genro, J P; Zeni, C P; Polanczyk, G V; Chazan, R; Rohde, L A; Hutz, M H

    2013-10-01

    Carboxylesterase 1 is the enzyme involved in methylphenidate (MPH) metabolism. The aim of this study was to evaluate the association between a -75 T>G polymorphism and appetite reduction in children with attention-deficit/hyperactivity disorder (ADHD). A sample of 213 children with ADHD was investigated. The primary outcome was appetite reduction measured by the Barkley Stimulant Side Effect Rating Scale applied at baseline, at 1 and 3 months of treatment. MPH doses were augmented until no further clinical improvement or significant adverse events occurred. The G allele presented a trend for association with appetite reduction scores (P=0.05). A significant interaction between the G allele and treatment over time for appetite reduction scores was also observed (P=0.03). The G allele carriers presented a higher risk for appetite reduction worsening when compared with T allele homozygotes (odds ratio=3.47, P=0.01). The present results suggest an influence of carboxylesterase 1 -75 T>G polymorphism on the worsening of appetite reduction with MPH treatment in youths with ADHD.

  6. Savannah River Site Footprint Reduction Results under the American Recovery and Reinvestment Act - 13302

    Energy Technology Data Exchange (ETDEWEB)

    Flora, Mary [Savannah River Nuclear Solutions Bldg. 730-4B, Aiken, SC 29808 (United States); Adams, Angelia [United States Department of Energy Bldg. 730-B, Aiken, SC 29808 (United States); Pope, Robert [United States Environmental Protection Agency Region IV Atlanta, GA 30303 (United States)

    2013-07-01

    The Savannah River Site (SRS) is an 802 square-kilometer United States Department of Energy (US DOE) nuclear facility located along the Savannah River near Aiken, South Carolina, managed and operated by Savannah River Nuclear Solutions. Construction of SRS began in the early 1950's to enhance the nation's nuclear weapons capability. Nuclear weapons material production began in the early 1950's, eventually utilizing five production reactors constructed to support the national defense mission. Past operations have resulted in releases of hazardous constituents and substances to soil and groundwater, resulting in 515 waste sites with contamination exceeding regulatory thresholds. More than 1,000 facilities were constructed onsite with approximately 300 of them considered radiological, nuclear or industrial in nature. In 2003, SRS entered into a Memorandum of Agreement with its regulators to accelerate the cleanup using an Area Completion strategy. The strategy was designed to focus cleanup efforts on the 14 large industrial areas of the site to realize efficiencies of scale in the characterization, assessment, and remediation activities. This strategy focuses on addressing the contaminated surface units and the vadose zone and addressing groundwater plumes subsequently. This approach streamlines characterization and remediation efforts as well as the required regulatory documentation, while enhancing the ability to make large-scale cleanup decisions. In February 2009, Congress approved the American Reinvestment and Recovery Act (ARRA) to create jobs and promote economic recovery. At SRS, ARRA funding was established in part to accelerate the completion of environmental remediation and facility deactivation and decommissioning (D and D). By late 2012, SRS achieved 85 percent footprint reduction utilizing ARRA funding by accelerating and coupling waste unit remediation with D and D of remnant facilities. Facility D and D activities were sequenced and

  7. Reduction in open field activity in the absence of memory deficits in the AppNL-G-F knock-in mouse model of Alzheimer's disease.

    Science.gov (United States)

    Whyte, Lauren S; Hemsley, Kim M; Lau, Adeline A; Hassiotis, Sofia; Saito, Takashi; Saido, Takaomi C; Hopwood, John J; Sargeant, Timothy J

    2018-01-15

    The recent development of knock-in mouse models of Alzheimer's disease provides distinct advantages over traditional transgenic mouse models that rely on over-expression of amyloid precursor protein. Two such knock-in models that have recently been widely adopted by Alzheimer's researchers are the App NL-F and App NL-G-F mice. This study aimed to further characterise the behavioural phenotype and amyloid plaque distribution of App NL-G-F/NL-G-F (C57BL/6J background) mice at six-months of age. An attempt to replicate a previous study that observed deficits in working memory in the Y-maze, showed no difference between App NL-G-F/NL-G-F and wild-type mice. Further assessment of these mice using the novel object recognition test and Morris water maze also revealed no differences between App NL-G-F/NL-G-F and wild-type mice. Despite a lack of demonstrated cognitive deficits, we report a reduction in locomotor/exploratory activity in an open field. Histological examination of App NL-G-F/NL-G-F mice showed widespread distribution of amyloid plaques at this age. We conclude that whilst at six-months of age, memory deficits are not sufficiently robust to be replicated in varying environments, amyloid plaque burden is significant in App NL-G-F/NL-G-F knock-in brain. Copyright © 2017 Elsevier B.V. All rights reserved.

  8. 7 CFR 33.60 - OMB control number assigned pursuant to the Paperwork Reduction Act.

    Science.gov (United States)

    2010-01-01

    ... MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE COMMODITY STANDARDS AND STANDARD CONTAINER REGULATIONS REGULATIONS ISSUED UNDER AUTHORITY OF THE EXPORT APPLE ACT...

  9. 7 CFR 59.400 - OMB control number assigned pursuant to the Paperwork Reduction Act.

    Science.gov (United States)

    2010-01-01

    ...) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 AND THE EGG PRODUCTS INSPECTION ACT (CONTINUED) LIVESTOCK MANDATORY REPORTING OMB Control Number § 59.400 OMB control number...

  10. Variation in total sugars and reductive sugars in the moss Pleurozium schreberi (hylocomiaceae) under water deficit conditions

    International Nuclear Information System (INIS)

    Montenegro Ruiz, Luis Carlos; Melgarejo Munoz, Luz Marina.

    2012-01-01

    The structural simplicity of the bryophytes exposed them easily to water stress, forcing them to have physiological and biochemical mechanisms that enable them to survive. This study evaluated the variation of total soluble sugars and reducing sugars in relation to relative water content, in Pleurozium schreberi when faced with low water content in the Paramo de Chingaza (Colombia) and under simulated conditions of water deficit in the laboratory. we found that total sugars increase when the plant is dehydrated and returned to their normal content when re-hydrated moss, this could be interpreted as a possible mechanism of osmotic adjustment and osmoprotection of the cell content and cellular structure. Reducing sugars showed no significant variation, showing that monosaccharides do not have a protective role during dehydration.

  11. 22 CFR 201.03 - OMB approval under the Paperwork Reduction Act.

    Science.gov (United States)

    2010-04-01

    .... The information is required from suppliers in order to receive payment for commodities or commodity..., and the Office of Management and Budget, Paperwork Reduction Project (0412-0514), Washington, DC 20503...

  12. 7 CFR 54.1034 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Science.gov (United States)

    2010-01-01

    ...) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 AND THE EGG PRODUCTS..., Processing, and Packaging of Livestock and Poultry Products § 54.1034 OMB control numbers assigned pursuant...

  13. Suicide risk reduction in youths with attention-deficit/hyperactivity disorder prescribed methylphenidate: A Taiwan nationwide population-based cohort study.

    Science.gov (United States)

    Liang, Sophie Hsin-Yi; Yang, Yao-Hsu; Kuo, Ting-Yu; Liao, Yin-To; Lin, Tzu-Chin; Lee, Yena; McIntyre, Roger S; Kelsen, Brent A; Wang, Tsu-Nai; Chen, Vincent Chin-Hung

    2018-01-01

    Attention-deficit/hyperactivity disorder (ADHD) youths have increased suicide risk. Nevertheless, the beneficial effects of methylphenidate (MPH) on suicide attempt have received relatively little attention. To investigate the MPH usage and the risk of suicide attempt among ADHD youths. We identified 84,898 youths less than 18 years old with ADHD diagnosis between 1997 and 2013 from National Health Insurance, and examined whether MPH use affected suicide attempt risk using Cox proportional-hazards models. Among ADHD youths, reduction of suicide risk was found in patients prescribed 90-180days of MPH after adjusting for confounding factors (hazard ratio (HR): 0.41, 95% confidence interval (CI): 0.19-0.90) and a greater reduction in those prescribed more than 180days of MPH (HR: 0.28, 95% CI: 0.17-0.48). We observed a 59% suicide attempt risk reduction among ADHD youths prescribed between 90 and 180days and a 72% risk reduction in those prescribed more than 180days of MPH. The protective benefit observed by the group prescribed MPH for longer duration underscores the importance of psychoeducation and compliance enhancement as part of ADHD management. Indication bias is identified as a limitation of this study, and future self-case control study to investigate the association between suicide attempt and ADHD medication is suggested. This nationwide population-based cohort study showed that among ADHD youths, reduction of suicide risk was observed in patients prescribed MPH for duration 90days and longer, underscoring the importance of appropriate ADHD pharmacotherapy and enhancing drug compliance. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  14. The Energy Policy Act of 1992 and reductions in greenhouse gas emissions: The petroleum industry perspective

    International Nuclear Information System (INIS)

    Baer, M.T.

    1994-01-01

    The Energy Policy Act of 1992 (EPAct) directs the US Department of Energy policies, programs and regulations to stabilize and reduce the quantities of greenhouse gas emissions. These objectives will be accomplished through the regulation of sources associated with the production, transportation/distribution, and end-use of energy resources. Almost all of the 30 titles of the Act affect these sources: from the energy efficiency provisions of Titles 1 and XXI to the alternative fuels and vehicles programs of Titles 3 through 5; from the global climate change requirements of Title XVI to the petroleum alternative research programs of Titles VI, XII, XIII, XX, and XXI; and from the multiple titles pertaining to the development and regulation of nuclear facilities, supplies, and waste. The goals of the law are to: (1) reduce the use of oil in the domestic energy mix from 40% in 1990 to 35% by the year 2005, (2) require the use of alternative fuels and alternative fuel vehicles in designated fleets, (3) replace up to 30% of motor fuels with ''replacement fuels'' by the year 2010, (4) increase the overall efficiency of consumer, residential, and commercial products, (5) reduce and stabilize the emissions of greenhouse gases, and (6) encourage the development and commercialization of renewable and non petroleum energy resources. All these goals are intended to reduce the emissions of greenhouse gases as well. The EPAct's potential to impact all forms of energy and all energy producers and suppliers is obvious and substantial. This paper assesses three goals of the EPAct, now under study by the petroleum industry, that will affect the production, supply, composition, and use of petroleum products, most notably gasoline and natural gas

  15. Recovery Act: SeaMicro Volume Server Power Reduction Research Development

    Energy Technology Data Exchange (ETDEWEB)

    Gary Lauterbach

    2012-03-22

    Cloud data centers are projected to be the fastest growing segment of the server market through 2015, according to IDC. Increasingly people and businesses rely on the Cloud to deliver digital content quickly and efficiently. Recovery Act funding from the Department of Energy has helped SeaMicro's technologies enhance the total cost of operation, performance and energy efficiency in large data center and Cloud environments. SeaMicro's innovative supercomputer fabric connects thousands of processor cores, memory, storage and input/output traffic. The company's fabric supports multiple processor instruction sets. Current systems featuring SeaMicro technology typically use one quarter the power and take one sixth the space of traditional servers with the same compute performance, yet deliver up to 12 times the bandwidth per core. Mozilla and eHarmony are two customers successfully using SeaMicro's technology. Numerous non-public customers have been successfully using the SeaMicro product in test and production facilities. As a result of the Recovery Act funding from the U.S. Department of Energy, more than 50 direct jobs were created at SeaMicro. To date, they primarily have been high-value, engineering jobs. Hardware, software and manufacturing engineering positions have been created, as well as sales and sales engineering. The positions have allowed SeaMicro to significantly accelerate engineering development and accelerate commercialization. As a result, commercialization and delivery to market are months ahead of initial schedule. Additional jobs were indirectly created through the development of the SeaMicro product. Through many years of research and hard work prior to receipt of public funding, SeaMicro was awarded 2 patents for its work. SeaMicro's product led the way for industry leaders to reconsider the market for low power servers and create new product lines. With valuable support of the U.S. Department of Energy and through Sea

  16. Tuition reduction is the key factor determining tax burden of graduate students under the Tax Cuts and Job Act.

    Science.gov (United States)

    Lawston, Patricia M; Parker, Michael T

    2017-01-01

    Background : The proposed Tax Cuts and Jobs Act (H.R.1) has stirred significant public debate on the future of American economics.  While supporters of the plan have championed it as a necessity for economic revitalization, detractors have pointed out areas of serious concern, particularly for low- and middle-income Americans.  One particularly alarming facet of the plan is the radical change to education finance programs and taxation of students in higher education.  Methods :  By analyzing actual income and tuition of a public and a private university student, as well as the 'average' graduate student, we investigated the effect of both the House and Senate versions of H.R. 1 on taxation of students of various family structures.  Results :  Our findings indicate that taxable tuition would be the greatest contributor to graduate student tax burden across all four categories of filing status.  However, when tuition reduction is upheld or a student is on sustaining fees rather than full tuition, graduate students would realize decreases in taxation. Conclusions :  Overall, we conclude that removal of tuition reduction would result in enormous tax burdens for graduate students and their families and that these effects are dependent not only on the status of the student in their degree program but also on their tuition and stipend, and therefore the institution they attend.

  17. Comparative treatment patterns, healthcare resource utilization and costs of atomoxetine and long-acting methylphenidate among children and adolescents with attention-deficit/hyperactivity disorder in Germany.

    Science.gov (United States)

    Greven, Peter; Sikirica, Vanja; Chen, Yaozhu J; Curtice, Tammy G; Makin, Charles

    2017-09-01

    Attention-deficit/hyperactivity disorder (ADHD) imposes a substantial burden on patients and their families. A retrospective, propensity score-matched cohort study compared treatment patterns, healthcare resource utilization (HRU) and costs among children/adolescents with ADHD aged 6-17 years at treatment initiation (index) in Germany who received atomoxetine (ATX) or long-acting methylphenidate (LA-MPH) monotherapy. Patients received at least one prescription for their index medication (ATX/LA-MPH) during 2006-2010; the first prescription marked the index date. ATX- and LA-MPH-indexed cohorts were matched 1:1 (n = 737); a patient subset was identified that had not received ADHD-indicated medications in 12 months prior to index (novel initiators: ATX, n = 486; LA-MPH, n = 488). Treatment patterns were evaluated among novel initiators, and HRU and costs among the matched cohorts in the 12 months after index. No significant differences in baseline characteristics were found between the novel initiator patient subsets. ATX-indexed novel initiators had significantly longer persistence to index medication [mean (standard deviation; SD) days: 222.0 (133.9) vs 203.2 (135.0), P = 0.029) but higher switching rates (8.8 vs 5.5 %, P = 0.045) than LA-MPH-indexed novel initiators. The total ATX-indexed cohort required more prescriptions [any medication; mean (SD): 20.9 (11.5) vs 15.7 (9.0), P < 0.001] and outpatient visits [mean (SD): 10.1 (6.3) vs 8.3 (5.3), P < 0.001], and incurred significantly higher total median healthcare costs (€1144 vs €541, P < 0.001) versus matched LA-MPH patients. These real-world data indicate that, among children/adolescents with ADHD in Germany, ATX-indexed patients may require more prescriptions and physician visits, and incur higher total healthcare costs, than matched LA-MPH patients.

  18. Dose-Response Effects of Long-Acting Liquid Methylphenidate in Children with Attention Deficit/Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD): A Pilot Study

    Science.gov (United States)

    Kim, Soo-Jeong; Shonka, Sophia; French, William P.; Strickland, Jennifer; Miller, Lindsey; Stein, Mark A.

    2017-01-01

    Attention deficit/hyperactivity disorder (ADHD) symptoms are common in youth with autism spectrum disorders (ASD) and are frequently treated with stimulant medications. Twenty-seven children were randomized to different dose titration schedules, and ADHD symptoms, tolerability, and aberrant behaviors were assessed weekly during a 6-week trial with…

  19. Treating attention-deficit/hyperactivity disorder beyond symptom control alone in children and adolescents: a review of the potential benefits of long-acting stimulants.

    NARCIS (Netherlands)

    Buitelaar, J.K.; Medori, R.

    2010-01-01

    Attention-deficit/hyperactivity disorder (ADHD), one of the most common neuropsychiatric conditions of childhood, often has a chronic course and persists into adulthood in many individuals. ADHD may have a clinically important impact on health-related quality of life in children, a significant

  20. Reductions in Negative Parenting Practices Mediate the Effect of a Family-School Intervention for Children with Attention Deficit Hyperactivity Disorder

    Science.gov (United States)

    Booster, Genery D.; Mautone, Jennifer A.; Nissley-Tsiopinis, Jenelle; Van Dyke, Devin; Power, Thomas J.

    2016-01-01

    Accumulating research has identified family behavioral interventions as an empirically supported psychosocial treatment for students with attention deficit hyperactivity disorder (ADHD). The mechanisms behind the effectiveness of these interventions, however, have been less well studied. The current study examined possible mediators of improvement…

  1. Age-related associative deficits and the isolation effect.

    Science.gov (United States)

    Badham, Stephen P; Maylor, Elizabeth A

    2013-01-01

    If all but one of the items in a list are similar (e.g., all black except one red), memory for the different item is enhanced (the isolation effect). Older adults generally show similar or smaller isolation effects compared to young adults, which has been attributed to age-related deficits in associative memory whereby older adults are less able to associate an isolated stimulus to its isolating feature. Experiment 1 examined the isolation effect for isolation based on spatial position, modality and color; in Experiment 2, the criterion for isolation was the associative relation between stimuli. The results consistently showed no differences between young and older participants in the magnitude of the isolation effect. Whilst age deficits in associative memory may act to reduce the isolation effect in older adults, age deficits in self-initiated processing and inhibitory functionality may counteract this reduction by enhancing the isolation effect in older adults.

  2. Learning and memory deficits consequent to reduction of the fragile X mental retardation protein result from metabotropic glutamate receptor-mediated inhibition of cAMP signaling in Drosophila.

    Science.gov (United States)

    Kanellopoulos, Alexandros K; Semelidou, Ourania; Kotini, Andriana G; Anezaki, Maria; Skoulakis, Efthimios M C

    2012-09-19

    Loss of the RNA-binding fragile X protein [fragile X mental retardation protein (FMRP)] results in a spectrum of cognitive deficits, the fragile X syndrome (FXS), while aging individuals with decreased protein levels present with a subset of these symptoms and tremor. The broad range of behavioral deficits likely reflects the ubiquitous distribution and multiple functions of the protein. FMRP loss is expected to affect multiple neuronal proteins and intracellular signaling pathways, whose identity and interactions are essential in understanding and ameliorating FXS symptoms. We used heterozygous mutants and targeted RNA interference-mediated abrogation in Drosophila to uncover molecular pathways affected by FMRP reduction. We present evidence that FMRP loss results in excess metabotropic glutamate receptor (mGluR) activity, attributable at least in part to elevation of the protein in affected neurons. Using high-resolution behavioral, genetic, and biochemical analyses, we present evidence that excess mGluR upon FMRP attenuation is linked to the cAMP decrement reported in patients and models, and underlies olfactory associative learning and memory deficits. Furthermore, our data indicate positive transcriptional regulation of the fly fmr1 gene by cAMP, via protein kinase A, likely through the transcription factor CREB. Because the human Fmr1 gene also contains CREB binding sites, the interaction of mGluR excess and cAMP signaling defects we present suggests novel combinatorial pharmaceutical approaches to symptom amelioration upon FMRP attenuation.

  3. Rebound effects with long-acting amphetamine or methylphenidate stimulant medication preparations among adolescent male drivers with attention-deficit/hyperactivity disorder.

    Science.gov (United States)

    Cox, Daniel J; Moore, Melissa; Burket, Roger; Merkel, R Lawrence; Mikami, Amori Yee; Kovatchev, Boris

    2008-02-01

    This study investigated whether OROS methylphenidate (OROS MPH, Concerta) or extended-release mixed amphetamine salts (se-AMPH ER, Adderall XR) were associated with worsening of driving performance, or drug rebound, relative to placebo 16-17 hours post-ingestion. Nineteen male adolescent drivers aged 17-19 with attention-deficit/hyperactivity disorder (ADHD) were compared on a virtual reality driving simulator and an on-road drive after taking 72 mg of OROS MPH, 30 mg of se-AMPH ER, or placebo. Medication was taken at 08:00 in a randomized, double-blind, placebo-controlled, crossover study. Participants drove a simulator at 17:00, 20:00, 23:00, and 01:00, and drove their own cars over a 16-mile road course at 24:00. The main outcome measures were composite scores of driving performance. Neither OROS MPH nor se-AMPH ER was associated with significant worsening of simulator performance relative to placebo 17 hours post-ingestion in group comparisons. However, inattentive on-road driving errors were significantly more common on se-AMPH ER relative to placebo at midnight (p = 0.04), suggesting possible rebound. During both late simulator and on-road testing, driving performance variance was approximately 300% greater during the se-AMPH ER compared to the OROS MPH condition.

  4. Reduction of 3-methoxytyramine concentrations in the caudate nucleus of rats after exposure to high-energy iron particles: evidence for deficits in dopaminergic neurons

    International Nuclear Information System (INIS)

    Hunt, W.A.; Dalton, T.K.; Joseph, J.A.; Rabin, B.M.

    1990-01-01

    Exposure to low doses of high-energy iron particles can alter motor behavior. The ability of rats to hang from a wire has been reported to be significantly degraded after exposure to doses as low as 0.5 Gy. In addition, deficits in the ability of acetylcholine to regulate dopamine release in the caudate nucleus (an area in the brain important for motor function) have been found. The concentrations of 3-methoxytyramine (3-MT), a metabolite of dopamine whose concentrations reflect dopamine release in vivo, were measured after rats were exposed to different doses of high-energy iron particles to gain further information about the effect of radiation on the dopaminergic system. Concentrations of 3-MT were significantly reduced 3 days after exposure to 5 Gy but returned to control values by 8 days. After 6 months, concentrations were again less than control values. Exposure to 5 Gy of high-energy electrons or gamma photons had no effect 3 days after exposure. Very high doses of electrons were needed to alter 3-MT concentrations. One hundred grays of electrons decreased 3-MT 30 min after irradiation but levels returned to control values by 60 min. Gamma photons had no effect after doses up to 200 Gy. These results provide further evidence that exposure to heavy particles can degrade motor behavior through an action on dopaminergic mechanisms and that this can occur after doses much lower than those needed for low-LET radiation

  5. Analysis & commentary. Health care reform is likely to widen federal budget deficits, not reduce them.

    Science.gov (United States)

    Holtz-Eakin, Douglas; Ramlet, Michael J

    2010-06-01

    The federal government faces a daunting fiscal outlook, which makes the budgetary impact of the Patient Protection and Affordable Care Act even more important. The official Congressional Budget Office (CBO) analysis indicates modest deficit reduction over the next ten years and beyond. We examine the underpinnings of the CBO's projection and conclude that it is built on a shaky foundation of omitted costs, premiums shifted from other entitlements, and politically dubious spending cuts and revenue increases. A more comprehensive and realistic projection suggests that the new reform law will raise the deficit by more than $500 billion during the first ten years and by nearly $1.5 trillion in the following decade.

  6. Rhodium-Coordinated Poly(arylene-ethynylene)-alt-Poly(arylene-vinylene) Copolymer Acting as Photocatalyst for Visible-Light-Powered NAD+/NADH Reduction

    Science.gov (United States)

    2014-01-01

    A 2,2′-bipyridyl-containing poly(arylene-ethynylene)-alt-poly(arylene-vinylene) polymer, acting as a light-harvesting ligand system, was synthesized and coupled to an organometallic rhodium complex designed for photocatalytic NAD+/NADH reduction. The material, which absorbs over a wide spectral range, was characterized by using various analytical techniques, confirming its chemical structure and properties. The dielectric function of the material was determined from spectroscopic ellipsometry measurements. Photocatalytic reduction of nucleotide redox cofactors under visible light irradiation (390–650 nm) was performed and is discussed in detail. The new metal-containing polymer can be used to cover large surface areas (e.g. glass beads) and, due to this immobilization step, can be easily separated from the reaction solution after photolysis. Because of its high stability, the polymer-based catalyst system can be repeatedly used under different reaction conditions for (photo)chemical reduction of NAD+. With this concept, enzymatic, photo-biocatalytic systems for solar energy conversion can be facilitated, and the precious metal catalyst can be recycled. PMID:25130570

  7. Is adjunctive pharmacotherapy in attention-deficit/hyperactivity disorder cost-effective in Canada: a cost-effectiveness assessment of guanfacine extended-release as an adjunctive therapy to a long-acting stimulant for the treatment of ADHD.

    Science.gov (United States)

    Lachaine, Jean; Sikirica, Vanja; Mathurin, Karine

    2016-01-16

    Attention-deficit/hyperactivity disorder (ADHD) is a common psychiatric disorder in children, with worldwide prevalence of ADHD varying from 5.9 to 7.1 %, depending on the reporter. In case of inadequate response to stimulants, combination therapy of stimulants and an adjunctive medication may improve the control of ADHD symptoms, reduce the dose-limiting adverse events, and help control comorbidities. To date, the only medication to be used for adjunctive therapy to psychostimulants is guanfacine extended release (GXR). The aim of this study was to assess the economic impact of GXR as an adjunct therapy with long-acting stimulants (GXR + stimulant) compared to long-acting stimulant monotherapy (stimulant alone) in the treatment of children and adolescents with ADHD in Canada. A Markov model was developed using health states defined based on the clinician-reported Clinical Global Impression-Severity (CGI-S) score (normal, mild, moderate, severe). Transition probabilities were calculated based on patient-level data from a published study. Long-acting stimulants available in Canada were considered in the base-case model: amphetamine mixed salts, methylphenidate HCl formulations, and lisdexamfetamine dimesylate. Analyses were conducted from a Canadian Ministry of Health (MoH; Ontario) and a societal perspective over a 1-year time horizon with weekly cycles. Over a 1-year time horizon, GXR + stimulant was associated with 0.655 quality-adjusted life year (QALY), compared to 0.627 QALY with stimulant alone, for a gain of 0.028 QALY. From a MoH perspective, GXR+ stimulant and stimulant alone were associated with total costs of $CA1,617 and $CA949, respectively (difference of $CA668), which resulted in an incremental cost-effectiveness ratio (ICER) of $CA23,720/QALY. From a societal perspective, GXR + stimulant and stimulant alone were associated with total costs of $CA3,915 and $CA3,582, respectively (difference of $CA334), which resulted in an ICER of $CA11

  8. Tuition reduction is the key factor determining tax burden of graduate students under the Tax Cuts and Job Act [version 2; referees: 2 approved

    Directory of Open Access Journals (Sweden)

    Patricia M. Lawston

    2018-02-01

    Full Text Available Background: The proposed Tax Cuts and Jobs Act (H.R.1 has stirred significant public debate on the future of American economics.  While supporters of the plan have championed it as a necessity for economic revitalization, detractors have pointed out areas of serious concern, particularly for low- and middle-income Americans.  One particularly alarming facet of the plan is the radical change to education finance programs and taxation of students in higher education.  Methods:  By analyzing actual income and tuition of a public and a private university student, as well as the ‘average’ graduate student, we investigated the effect of both the House and Senate versions of H.R. 1 on taxation of students of various family structures.  Results:  Our findings indicate that taxable tuition would be the greatest contributor to graduate student tax burden across all four categories of filing status.  However, when tuition reduction is upheld or a student is on sustaining fees rather than full tuition, graduate students would realize decreases in taxation. Conclusions:  Overall, we conclude that removal of tuition reduction would result in enormous tax burdens for graduate students and their families and that these effects are dependent not only on the status of the student in their degree program but also on their tuition and stipend, and therefore the institution they attend.

  9. Visual search deficits in amblyopia.

    Science.gov (United States)

    Tsirlin, Inna; Colpa, Linda; Goltz, Herbert C; Wong, Agnes M F

    2018-04-01

    Amblyopia is a neurodevelopmental disorder defined as a reduction in visual acuity that cannot be corrected by optical means. It has been associated with low-level deficits. However, research has demonstrated a link between amblyopia and visual attention deficits in counting, tracking, and identifying objects. Visual search is a useful tool for assessing visual attention but has not been well studied in amblyopia. Here, we assessed the extent of visual search deficits in amblyopia using feature and conjunction search tasks. We compared the performance of participants with amblyopia (n = 10) to those of controls (n = 12) on both feature and conjunction search tasks using Gabor patch stimuli, varying spatial bandwidth and orientation. To account for the low-level deficits inherent in amblyopia, we measured individual contrast and crowding thresholds and monitored eye movements. The display elements were then presented at suprathreshold levels to ensure that visibility was equalized across groups. There was no performance difference between groups on feature search, indicating that our experimental design controlled successfully for low-level amblyopia deficits. In contrast, during conjunction search, median reaction times and reaction time slopes were significantly larger in participants with amblyopia compared with controls. Amblyopia differentially affects performance on conjunction visual search, a more difficult task that requires feature binding and possibly the involvement of higher-level attention processes. Deficits in visual search may affect day-to-day functioning in people with amblyopia.

  10. α-Asarone Attenuates Cognitive Deficit in a Pilocarpine-Induced Status Epilepticus Rat Model via a Decrease in the Nuclear Factor-κB Activation and Reduction in Microglia Neuroinflammation

    Directory of Open Access Journals (Sweden)

    Hui-juan Liu

    2017-12-01

    Full Text Available BackgroundTemporal lobe epilepsy (TLE is one of the most drug-resistant types of epilepsy with about 80% of TLE patients falling into this category. Increasing evidence suggests that neuroinflammation, which has a critical role in the epileptogenesis of TLE, is associated with microglial activation. Therefore, agents that act toward the alleviation in microglial activation and the attenuation of neuroinflammation are promising candidates to treat TLE. α-Asarone is a major active ingredient of the Acori Graminei Rhizoma used in Traditional Chinese Medicine, which has been used to improve various disease conditions including stroke and convulsions. In addition, an increasing number of studies suggested that α-asarone can attenuate microglia-mediated neuroinflammation. Thus, we hypothesized that α-asarone is a promising neuroprotective agent for the treatment of the TLE.MethodsThe present study evaluated the therapeutic effects of α-asarone on microglia-mediated neuroinflammation and neuroprotection in vitro and in vivo, using an untreated control group, a status epilepticus (SE-induced group, and an SE-induced α-asarone pretreated group. A pilocarpine-induced rat model of TLE was established to investigate the neuroprotective effects of α-asarone in vivo. For the in vitro study, lipopolysaccharide (LPS-stimulated primary cultured microglial cells were used.ResultsThe results indicated that the brain microglial activation in the rats of the SE rat model led to important learning and memory deficit. Preventive treatment with α-asarone restrained microglial activation and reduced learning and memory deficit. In the in vitro studies, α-asarone significantly suppressed proinflammatory cytokine production in primary cultured microglial cells and attenuated the LPS-stimulated neuroinflammatory responses. Our mechanistic study revealed that α-asarone inhibited inflammatory processes by regulation the transcription levels of kappa-B, by blocking

  11. Brassinosteroids improve photosystem II efficiency, gas exchange, antioxidant enzymes and growth of cowpea plants exposed to water deficit.

    Science.gov (United States)

    Lima, J V; Lobato, A K S

    2017-01-01

    Water deficit is considered the main abiotic stress that limits agricultural production worldwide. Brassinosteroids (BRs) are natural substances that play roles in plant tolerance against abiotic stresses, including water deficit. This research aims to determine whether BRs can mitigate the negative effects caused by water deficiency, revealing how BRs act and their possible contribution to increased tolerance of cowpea plants to water deficit. The experiment was a factorial design with the factors completely randomised, with two water conditions (control and water deficit) and three levels of brassinosteroids (0, 50 and 100 nM 24-epibrassinolide; EBR is an active BRs). Plants sprayed with 100 nM EBR under the water deficit presented significant increases in Φ PSII , q P and ETR compared with plants subjected to the water deficit without EBR. With respect to gas exchange, P N , E and g s exhibited significant reductions after water deficit, but application of 100 nM EBR caused increases in these variables of 96, 24 and 33%, respectively, compared to the water deficit + 0 nM EBR treatment. To antioxidant enzymes, EBR resulted in increases in SOD, CAT, APX and POX, indicating that EBR acts on the antioxidant system, reducing cell damage. The water deficit caused significant reductions in Chl a , Chl b and total Chl, while plants sprayed with 100 nM EBR showed significant increases of 26, 58 and 33% in Chl a , Chl b and total Chl, respectively. This study revealed that EBR improves photosystem II efficiency, inducing increases in Φ PSII , q P and ETR. This substance also mitigated the negative effects on gas exchange and growth induced by the water deficit. Increases in SOD, CAT, APX and POX of plants treated with EBR indicate that this steroid clearly increased the tolerance to the water deficit, reducing reactive oxygen species, cell damage, and maintaining the photosynthetic pigments. Additionally, 100 nM EBR resulted in a better dose-response of cowpea

  12. PF-05231023, a long-acting FGF21 analogue, decreases body weight by reduction of food intake in non-human primates.

    Science.gov (United States)

    Thompson, W Clayton; Zhou, Yingjiang; Talukdar, Saswata; Musante, Cynthia J

    2016-08-01

    PF-05231023, a long-acting FGF21 analogue, is a promising potential pharmacotherapy for the treatment of obesity and associated comorbidities. Previous studies have shown the potential of FGF21 and FGF21-like compounds to decrease body weight in mice, non-human primates, and humans; the precise mechanisms of action remain unclear. In particular, there have been conflicting reports on the degree to which FGF21-induced weight loss in non-human primates is attributable to a decrease in food intake versus an increase in energy expenditure. Here, we present a semi-mechanistic mathematical model of energy balance and body composition developed from similar work in mice. This model links PF-05231023 administration and washout to changes in food intake, which in turn drives changes in body weight. The model is calibrated to and compared with recently published data from cynomolgus macaques treated with PF-05231023, demonstrating its accuracy in describing pharmacotherapy-induced weight loss in these animals. The results are consistent with the hypothesis that PF-05231023 decreases body weight in cynomolgus macaques solely by a reduction in food intake, with no direct effect on energy expenditure.

  13. Electroencephalography reveals lower regional blood perfusion and atrophy of the temporoparietal network associated with memory deficits and hippocampal volume reduction in mild cognitive impairment due to Alzheimer’s disease

    Directory of Open Access Journals (Sweden)

    Moretti DV

    2015-02-01

    Full Text Available Davide Vito MorettiNational Institute for the research and cure of Alzheimer’s disease, S. John of God, Fatebenefratelli, Brescia, Italy Background: An increased electroencephalographic (EEG upper/lower alpha power ratio has been associated with less regional blood perfusion, atrophy of the temporoparietal region of the brain, and reduction of hippocampal volume in subjects affected by mild cognitive impairment due to Alzheimer’s disease as compared with subjects who do not develop the disease. Moreover, EEG theta frequency activity is quite different in these groups. This study investigated the correlation between biomarkers and memory performance.Methods: EEG α3/α2 power ratio and cortical thickness were computed in 74 adult subjects with prodromal Alzheimer’s disease. Twenty of these subjects also underwent assessment of blood perfusion by single-photon emission computed tomography (SPECT. Pearson’s r was used to assess the correlation between cortical thinning, brain perfusion, and memory impairment.Results: In the higher α3/α2 frequency power ratio group, greater cortical atrophy and lower regional perfusion in the temporoparietal cortex was correlated with an increase in EEG theta frequency. Memory impairment was more pronounced in the magnetic resonance imaging group and SPECT groups.Conclusion: A high EEG upper/low alpha power ratio was associated with cortical thinning and less perfusion in the temporoparietal area. Moreover, atrophy and less regional perfusion were significantly correlated with memory impairment in subjects with prodromal Alzheimer’s disease. The EEG upper/lower alpha frequency power ratio could be useful for identifying individuals at risk for progression to Alzheimer’s dementia and may be of value in the clinical context.Keywords: electroencephalography, perfusion, atrophy, temporoparietal network, memory deficits, hippocampal volume, mild cognitive impairment, Alzheimer’s disease

  14. Long-acting methylphenidate-OROS in youths with attention-deficit hyperactivity disorder suboptimally controlled with immediate-release methylphenidate : a study of cost effectiveness in The Netherlands

    NARCIS (Netherlands)

    Faber, Adrianne; van Agthoven, Michel; Kalverdijk, Luuk J; Tobi, Hiltje; de Jong-van den Berg, Lolkje T W; Annemans, Lieven; Postma, Maarten J

    2008-01-01

    Background: Attention-deficit hyperactivity disorder (ADHD) is the most common mental health disorder in youths. Stimulants are the drugs of first choice in the treatment of ADHD. It has been suggested that full costs associated with the treatment of ADHD may be reduced by once-daily administration

  15. Long-Acting Methylphenidate-OROS in Youths with Attention-Deficit Hyperactivity Disorder Suboptimally Controlled with Immediate-Release Methylphenidate. A study of cost effectiveness in The Netherlands.

    NARCIS (Netherlands)

    Faber, A.; Agthoven, van M.; Kalverdijk, L.J.; Tobi, H.; Jong-van den Berg, de L.T.W.; Annemans, L.; Postma, M.J.

    2008-01-01

    BACKGROUND: Attention-deficit hyperactivity disorder (ADHD) is the most common mental health disorder in youths. Stimulants are the drugs of first choice in the treatment of ADHD. It has been suggested that full costs associated with the treatment of ADHD may be reduced by once-daily administration

  16. The 21st Century Cures Act Implications for the Reduction of Racial Health Disparities in the US Criminal Justice System: a Public Health Approach.

    Science.gov (United States)

    Cole, Donna M; Thomas, Dawna Marie; Field, Kelsi; Wool, Amelia; Lipiner, Taryn; Massenberg, Natalie; Guthrie, Barbara J

    2017-11-09

    Past drug epidemics have disproportionately criminalized drug addiction among African Americans, leading to disparate health outcomes, increased rates of HIV/AIDS, and mass incarceration. Conversely, the current opioid addiction crisis in the USA focuses primarily on white communities and is being addressed as a public health problem. The 21st Century Cures Act has the potential to reduce racial health disparities in the criminal justice system through the Act's public health approach to addiction and mental health issues. The 21st Century Cures Act is a progressive step in the right direction; however, given the historical context of segregation and the criminalization of drug addiction among African Americans, the goals of health equity are at risk of being compromised. This paper discusses the implications of this landmark legislation and its potential to decrease racial health disparities, highlighting the importance of ensuring that access to treatment and alternatives to incarceration must include communities of color. In this paper, the authors explain the key components of the 21st Century Cures Act that are specific to criminal justice reform, including a key objective, which is treatment over incarceration. We suggest that without proper attention to how, and where, funding mechanisms are distributed, the 21st Century Cures Act has the potential to increase racial health disparities rather than alleviate them.

  17. Impact of the Pharma Economic Act on Diffusion of Innovation and Reduction of Costs in the Hungarian Prescription Drug Market (2007-2010).

    Science.gov (United States)

    Hren, Rok

    In this study, we examined the impact of the Pharma Economic Act, which was introduced in Hungary in 2007. We used detailed data on the Hungarian prescription drug market, which had been made publicly available by the authorities. We evaluated the effect of the Pharma Economic Act on both dynamic and static efficiencies and also on equity, which has been historically a controversial issue in Hungary. We analyzed the overall prescription drug market and statin and atorvastatin markets; as a proxy for determining dynamic efficiency, we examined the oncology drug market for some specific products (e.g., bortezomib) and the long-acting atypical antipsychotic drugs market. There is no denying that the authorities managed to control the overall prescription drug costs; however, they were still paying excessive rents for off-patent drugs. Examples of oncology and long-acting atypical antipsychotic drugs showed that the diffusion of innovation was on per-capita basis at least comparable to G-5 countries. While the share of out-of-pocket co-payments markedly increased and the reimbursement was lowered, the concurrent price decreases often meant that the co-payment per milligram of a given dispensed drug was actually lower than that before the Act, thereby benefiting the patient. It appears that strong mechanisms to control volume rather than price on the supply side (marketing authorization holders) contained the drug expenditure, while offering enough room to strive for innovation. Making data on prescription drug expenditures and associated co-payments publicly available is an item that should be definitely followed by the surrounding jurisdictions. Copyright © 2013, International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc.

  18. Impact of regulated deficit irrigation on the physiological ...

    African Journals Online (AJOL)

    2011

    2012-03-22

    Mar 22, 2012 ... in plant response to water deficit under field conditions ... firstly related to the reduction in photosynthesis and CO2 ... However, varieties with the highest osmotic ... Indeed, the high potassium consumption in both stressed.

  19. Reduction of undesired lateral forces acting on the flapper of a flapper–nozzle pilot valve by using an innovative flapper shape

    International Nuclear Information System (INIS)

    Zhang, Shengzhuo; Aung, Nay Zar; Li, Songjing

    2015-01-01

    Highlights: • The simulated flow rate and main flow force show a good agreement with experiments. • The innovative flapper has little influence on the flow-pressure characteristics. • The innovative flapper can greatly reduce the Y direction force on the upper part. • The innovative flapper reduces both the X and Z direction forces on the lower part. - Abstract: The stability and dynamic performance of a flapper–nozzle pilot valve significantly depend on the flow forces acting on the flapper. Due to the shape of the flapper and flow structure in the flapper–nozzle pilot valve there are undesired lateral forces acting on the flapper, which are very potential to interfere with the stability of the flapper. Aiming to reduce these undesired lateral forces, an innovative flapper shape is proposed and a comparative study of flow forces acting on the two different flapper shapes is conducted. A simple rectangle shape is selected as the innovative flapper shape. The flow forces acting on the traditional flapper shape and innovative flapper shape are evaluated by means of CFD (Computational Fluid Dynamics) simulations and verified with the results from the semi-experimental approach. The evaluation of the flow forces is performed for each flapper shape with two different flapper–nozzle clearances of 0.10 mm and 0.05 mm under seven different flow conditions with the variation of inlet pressures from 1 MPa to 7 MPa. A good agreement between CFD results and semi-experimental results shows that the proposed innovative flapper shape has no effect on flow control characteristics since it is giving approximately the same flow rate and main flow force as the traditional flapper shape at every flow condition. Meanwhile the innovative flapper shape effectively reduces the undesired lateral forces acting on the flapper by altering the flow structure and reducing the strength of the jet flow and cavitation occurred in the flow field of flapper–nozzle pilot valve. At the

  20. An unexpected role for the yeast nucleotide exchange factor Sil1 as a reductant acting on the molecular chaperone BiP

    Science.gov (United States)

    Siegenthaler, Kevin D; Pareja, Kristeen A; Wang, Jie; Sevier, Carolyn S

    2017-01-01

    Unfavorable redox conditions in the endoplasmic reticulum (ER) can decrease the capacity for protein secretion, altering vital cell functions. While systems to manage reductive stress are well-established, how cells cope with an overly oxidizing ER remains largely undefined. In previous work (Wang et al., 2014), we demonstrated that the chaperone BiP is a sensor of overly oxidizing ER conditions. We showed that modification of a conserved BiP cysteine during stress beneficially alters BiP chaperone activity to cope with suboptimal folding conditions. How this cysteine is reduced to reestablish 'normal' BiP activity post-oxidative stress has remained unknown. Here we demonstrate that BiP's nucleotide exchange factor – Sil1 – can reverse BiP cysteine oxidation. This previously unexpected reductant capacity for yeast Sil1 has potential implications for the human ataxia Marinesco-Sjögren syndrome, where it is interesting to speculate that a disruption in ER redox-signaling (due to genetic defects in SIL1) may influence disease pathology. DOI: http://dx.doi.org/10.7554/eLife.24141.001 PMID:28257000

  1. Acute IPPS - Readmissions Reduction Program

    Data.gov (United States)

    U.S. Department of Health & Human Services — Section 3025 of the Affordable Care Act added section 1886(q) to the Social Security Act establishing the Hospital Readmissions Reduction Program, which requires CMS...

  2. Direct-acting Antivirals in Kidney Transplant Patients: Successful Hepatitis C Treatment and Short Term Reduction in Urinary Protein/Creatinine Ratios

    Directory of Open Access Journals (Sweden)

    Michael R. Goetsch

    2017-09-01

    Full Text Available Introduction: The role of Hepatitis C Virus (HCV clearance in long-term kidney graft survival is unknown. In this study, we examined short-term trends of urinary protein/creatinine (P/C ratios in a cohort of HCV-infected kidney transplant recipients with stable graft function and treated with direct-acting antivirals (DAAs. Methods: We conducted a retrospective study of 19 kidney transplant patients with chronic HCV infection treated with DAAs at the University of Alabama at Birmingham 1917 Viral Hepatitis Clinic between January 2013 and June 2016. Markers of glomerular damage were assessed using average protein/creatinine (P/C ratios measured pre- and post-treatment. We also described treatment efficacy using sustained virologic response at 12 weeks post-HCV treatment (SVR12. Results: The median age of the 19 patients included was 59 years (Q1=58, Q3=64 at completion of treatment. Of these patients, 68% were African American, 32% were White and 63% were male. The median time between kidney transplant and initiation of DAA therapy was 2.25 years (Q1=0.79, Q3=3.79. Post-treatment P/C ratios (median=0.127, Q1=0.090, Q3=0.220 were significantly lower (p=0.01 than pre-treatment ratios (median=0.168, Q1=0.118, Q3=0.385. P/C ratios decreased in 14 of 19 patients (74% with median change of -0.072 (median percent change= -40%. Post-treatment eGFRs (median=58.9, Q1=48.9, Q3=72.3 were not significantly different (p=0.82 than the pre-treatment values (median=57.0, Q1=48.8, Q3=67.8. Conclusions: In this preliminary study, there was a statistically significant decrease in P/C ratios associated with HCV clearance, suggesting a potential role for DAAs in improving kidney graft survival. Larger cohort studies will be needed to assess the clinical and long-term benefits of DAAs in this special population of HCV infected patients.

  3. The Twin Deficits Hypothesis: An Empirical Analysis for Tanzania

    Directory of Open Access Journals (Sweden)

    Manamba Epaphra

    2017-09-01

    Full Text Available This paper examines the relationship between current account and government budget deficits in Tanzania. The paper tests the validity of the twin deficits hypothesis, using annual time series data for the 1966-2015 period. The paper is thought to be significant because the concept of the twin deficit hypothesis is fraught with controversy. Some researches support the hypothesis that there is a positive relationship between current account deficits and fiscal deficits in the economy while others do not. In this paper, the empirical tests fail to reject the twin deficits hypothesis, indicating that rising budget deficits put more strain on the current account deficits in Tanzania. Specifically, the Vector Error Correction Model results support the conventional theory of a positive relationship between fiscal and external balances, with a relatively high speed of adjustment toward the equilibrium position. This evidence is consistent with a small open economy. To address the problem that may result from this kind of relationship, appropriate policy variables for reducing budget deficits such as reduction in non-development expenditure, enhancement of domestic revenue collection and actively fight corruption and tax evasion should be adopted. The government should also target export oriented firms and encourage an import substitution industry by creating favorable business environments.

  4. Privacy Act

    Science.gov (United States)

    Learn about the Privacy Act of 1974, the Electronic Government Act of 2002, the Federal Information Security Management Act, and other information about the Environmental Protection Agency maintains its records.

  5. Attention deficit hyperactivity disorder (ADHD)

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/001551.htm Attention deficit hyperactivity disorder To use the sharing features on this page, please enable JavaScript. Attention deficit hyperactivity disorder (ADHD) is a problem caused by ...

  6. Beyond the knowledge deficit

    DEFF Research Database (Denmark)

    Hansen, Janus Staffan; Holm, Lotte; Frewer, Lynn

    2003-01-01

    The paper reviews psychological and social scientific research on lay attitudes to food risks. Many experts (scientists, food producers and public health advisors) regard public unease about food risks as excessive. This expert-lay discrepancy is often attributed to a 'knowledge deficit' among la...... in institutions and experts. It suggests that an interdisciplinary, contextualised and psychologically sound approach to the study of risk is needed.......The paper reviews psychological and social scientific research on lay attitudes to food risks. Many experts (scientists, food producers and public health advisors) regard public unease about food risks as excessive. This expert-lay discrepancy is often attributed to a 'knowledge deficit' among lay...... people. However, much research in psychology and sociology suggests that lay risk assessments are complex, situationally sensitive expressions of personal value systems. The paper is organised around four themes: risk perception, the communication of risk, lay handling of risk, and public trust...

  7. Attention Deficit Hyperactivity Disorder

    OpenAIRE

    Jaime O. Oliver

    2017-01-01

    Attention Deficit Hyperactivity Disorder (ADHD) is considered as among the most common yet serious brain disorders significant number of children are subjected to; the seriousness of which manifests in the ability of the disorder to continue to show up even after the childhood years, during the period of adolescence as well as adulthood. Considering the findings delivered by Brain Imaging Studies conducted on youth, it is revealed that people suffering from ADHD experiences del...

  8. Attention deficits and divorce.

    Science.gov (United States)

    Bouchard, Geneviève; Saint-Aubin, Jean

    2014-09-01

    Building on previous work on the role of attention deficits associated with the regulation of executive control in psychiatric disorders, we examine whether these attention deficits are related to an interpersonal disturbance, the experience of divorce. Attentional capacities of 95 randomly selected couples from the general population were measured with a well-established task, the Attentional Network Task, which assesses the efficiency of 3 attention networks (that is, alerting, orienting, and executive control). Among the 190 participants, 32 had experienced a divorce in the past. ANCOVAs were used to compare divorced people in marital or cohabiting unions with people in first unions in their performance on this purely cognitive task. Our findings indicate that divorced people who are currently living in a cohabiting relationship show significantly lower executive control than other adults living as couples, after controlling for sex, age, income, and education. This subgroup of divorced people not only exhibit greater difficulty in responding to some stimuli while ignoring irrelevant ones but also manifest cognitive deficits in conflict resolution. This study highlights the links between attention and the long-term maintenance of intimate relationships. Our results may have important implications for the identification of people at risk for divorce.

  9. Ballistic deficit correction

    International Nuclear Information System (INIS)

    Duchene, G.; Moszynski, M.; Curien, D.

    1991-01-01

    The EUROGAM data-acquisition has to handle a large number of events/s. Typical in-beam experiments using heavy-ion fusion reactions assume the production of about 50 000 compound nuclei per second deexciting via particle and γ-ray emissions. The very powerful γ-ray detection of EUROGAM is expected to produce high-fold event rates as large as 10 4 events/s. Such high count rates introduce, in a common dead time mode, large dead times for the whole system associated with the processing of the pulse, its digitization and its readout (from the preamplifier pulse up to the readout of the information). In order to minimize the dead time the shaping time constant τ, usually about 3 μs for large volume Ge detectors has to be reduced. Smaller shaping times, however, will adversely affect the energy resolution due to ballistic deficit. One possible solution is to operate the linear amplifier, with a somewhat smaller shaping time constant (in the present case we choose τ = 1.5 μs), in combination with a ballistic deficit compensator. The ballistic deficit can be corrected in different ways using a Gated Integrator, a hardware correction or even a software correction. In this paper we present a comparative study of the software and hardware corrections as well as gated integration

  10. Increasing Northern Hemisphere water deficit

    Science.gov (United States)

    McCabe, Gregory J.; Wolock, David M.

    2015-01-01

    A monthly water-balance model is used with CRUTS3.1 gridded monthly precipitation and potential evapotranspiration (PET) data to examine changes in global water deficit (PET minus actual evapotranspiration) for the Northern Hemisphere (NH) for the years 1905 through 2009. Results show that NH deficit increased dramatically near the year 2000 during both the cool (October through March) and warm (April through September) seasons. The increase in water deficit near 2000 coincides with a substantial increase in NH temperature and PET. The most pronounced increases in deficit occurred for the latitudinal band from 0 to 40°N. These results indicate that global warming has increased the water deficit in the NH and that the increase since 2000 is unprecedented for the 1905 through 2009 period. Additionally, coincident with the increase in deficit near 2000, mean NH runoff also increased due to increases in P. We explain the apparent contradiction of concurrent increases in deficit and increases in runoff.

  11. The Contribution of Deficits in Emotional Clarity to Stress Responses and Depression

    OpenAIRE

    Flynn, Megan; Rudolph, Karen D.

    2010-01-01

    This research investigated the contribution of deficits in emotional clarity to children’s socioemotional adjustment. Specifically, this study examined the proposal that deficits in emotional clarity are associated with maladaptive interpersonal stress responses, and that maladaptive interpersonal stress responses act as a mechanism linking deficits in emotional clarity to childhood depressive symptoms. Participants included 345 3rd graders (M age = 8.89, SD = .34) assessed at two waves, appr...

  12. A neurocomputational account of reward and novelty processing and effects of psychostimulants in attention deficit hyperactivity disorder.

    Science.gov (United States)

    Sethi, Arjun; Voon, Valerie; Critchley, Hugo D; Cercignani, Mara; Harrison, Neil A

    2018-05-01

    Computational models of reinforcement learning have helped dissect discrete components of reward-related function and characterize neurocognitive deficits in psychiatric illnesses. Stimulus novelty biases decision-making, even when unrelated to choice outcome, acting as if possessing intrinsic reward value to guide decisions toward uncertain options. Heightened novelty seeking is characteristic of attention deficit hyperactivity disorder, yet how this influences reward-related decision-making is computationally encoded, or is altered by stimulant medication, is currently uncertain. Here we used an established reinforcement-learning task to model effects of novelty on reward-related behaviour during functional MRI in 30 adults with attention deficit hyperactivity disorder and 30 age-, sex- and IQ-matched control subjects. Each participant was tested on two separate occasions, once ON and once OFF stimulant medication. OFF medication, patients with attention deficit hyperactivity disorder showed significantly impaired task performance (P = 0.027), and greater selection of novel options (P = 0.004). Moreover, persistence in selecting novel options predicted impaired task performance (P = 0.025). These behavioural deficits were accompanied by a significantly lower learning rate (P = 0.011) and heightened novelty signalling within the substantia nigra/ventral tegmental area (family-wise error corrected P attention deficit hyperactivity disorder participants' overall task performance (P = 0.011), increased reward-learning rates (P = 0.046) and enhanced their ability to differentiate optimal from non-optimal novel choices (P = 0.032). It also reduced substantia nigra/ventral tegmental area responses to novelty. Preliminary cross-sectional evidence additionally suggested an association between long-term stimulant treatment and a reduction in the rewarding value of novelty. These data suggest that aberrant substantia nigra/ventral tegmental area novelty processing plays an

  13. The Contribution of Deficits in Emotional Clarity to Stress Responses and Depression

    Science.gov (United States)

    Flynn, Megan; Rudolph, Karen D.

    2010-01-01

    This research investigated the contribution of deficits in emotional clarity to children's socioemotional adjustment. Specifically, this study examined the proposal that deficits in emotional clarity are associated with maladaptive interpersonal stress responses, and that maladaptive interpersonal stress responses act as a mechanism linking…

  14. ACTS 2014

    DEFF Research Database (Denmark)

    Co-curator of ACTS 2014 together with Rasmus Holmboe, Judith Schwarzbart and Sanne Kofoed. ACTS is the Museum of Contemporary Art’s international bi-annual festival. ACTS was established in 2011 and, while the primary focus is on sound and performance art, it also looks toward socially oriented art....... For the 2014 festival, the museum has entered into a collaboration with the Department for Performance Design at Roskilde University – with continued focus on sound and performance art, and social art in public spaces. With ACTS, art moves out of its usual exhibition space and instead utilizes the city, its...... various possibilities and public spaces as a stage. ACTS takes place in and around the museum and diverse locations in Roskilde city. ACTS is partly curated by the museum staff and partly by guest curators. ACTS 2014 is supported by Nordea-fonden and is a part of the project The Museum goes downtown....

  15. Ischemia may be the primary cause of the neurologic deficits in classic migraine

    DEFF Research Database (Denmark)

    Skyhøj Olsen, T; Friberg, L; Lassen, N A

    1987-01-01

    This study investigates whether the cerebral blood flow reduction occurring in attacks of classic migraine is sufficient to cause neurologic deficits. Regional cerebral blood flow measured with the xenon 133 intracarotid injection technique was analyzed in 11 patients in whom a low-flow area...... ischemia and neurologic deficits. Hence, this study suggests a vascular origin of the prodromal neurologic deficits that may accompany attacks of classic migraine....

  16. [DMS-5 - attention-deficit/hyperactivity disorder].

    Science.gov (United States)

    Banaschewski, Tobias; Döpfner, Manfred

    2014-07-01

    Modifications to the DSM-5 criteria for the diagnosis of attention-deficit/hyperactivity disorders are described and discussed. The main modifications concern the onset of the disorder, the reduction on the number of criteria fulfilled for a diagnosis in patients aged 17 years or older, and the elimination of autism spectrum disorders as an exclusion criterion for this diagnosis. These changes are mainly welcomed. However, the demanded increase in the age for the latest onset of the disorder may prove to be problematic.

  17. Attention Deficit Hyperactivity Disorder

    Science.gov (United States)

    Matthews, Marguerite; Nigg, Joel T.

    2014-01-01

    Over the last two decades, there have been numerous technical and methodological advances available to clinicians and researchers to better understand attention deficit hyperactivity disorder (ADHD) and its etiology. Despite the growing body of literature investigating the disorder’s pathophysiology, ADHD remains a complex psychiatric disorder to characterize. This chapter will briefly review the literature on ADHD, with a focus on its history, the current genetic insights, neurophysiologic theories, and the use of neuroimaging to further understand the etiology. We address some of the major concerns that remain unclear about ADHD, including subtype instability, heterogeneity, and the underlying neural correlates that define the disorder. We highlight that the field of ADHD is rapidly evolving; the descriptions provided here will hopefully provide a sturdy foundation for which to build and improve our understanding of the disorder. PMID:24214656

  18. Defining Efficient Deficit Irrigation for Winegrape Cultivars Merlot and Cabernet Sauvignon under Semiarid Conditions

    Science.gov (United States)

    Efficient deficit irrigation balances enhanced berry attributes with acceptable reduction in yield. The present study relates pre and post-veraison midday leaf water potential with the growth and composition of east and west-facing berries. Two deficit irrigation treatments were applied over four g...

  19. Canada's Clean Air Act

    International Nuclear Information System (INIS)

    2006-01-01

    This paper provided an outline of Canada's Clean Air Act and examined some of the regulatory changes that will occur as a result of its implementation. The Act is being introduced to strengthen the legislative basis for taking action on reducing air pollution and GHGs, and will allow the government to regulate both indoor and outdoor air pollutants and GHGs. The Act will require the Ministers of the Environment and Health to establish national air quality objectives, as well as to monitor and report on their attainment. The Canadian Environmental Protection Act will be amended to enable the government to regulate the blending of fuels and their components. The Motor Vehicle Fuel Consumption Standards Act will also be amended to enhance the government's authority to regulate vehicle fuel efficiency. The Energy Efficiency Act will also be expanded to allow the government to set energy efficiency standards and labelling requirements for a wider range of consumer and commercial products. The Act will commit to short, medium and long-term industrial air pollution targets. Regulations will be proposed for emissions from industry; on-road and off-road vehicles and engines; and consumer and commercial products. It was concluded that the Government of Canada will continue to consult with provinces, territories, industries and Canadians to set and reach targets for the reduction of both indoor and outdoor air pollutants and GHG emissions. 6 figs

  20. Attention deficit hyperactivity disorder symptoms mediate early-onset smoking

    NARCIS (Netherlands)

    Huizink, A.C.; Van Lier, P.A.C.; Crijnen, A.A.M.

    2009-01-01

    Background/Aims: Symptoms of attention deficit hyperactivity disorder (ADHD) have often been associated with early-onset smoking. We hypothesize that reductions in ADHD symptoms due to an intervention have a mediating effect on early-onset smoking. Methods: In a universal, school-based, randomized

  1. Attention Deficit Hyperactivity Disorder Symptoms Mediate Early-Onset Smoking

    NARCIS (Netherlands)

    Huizink, A.C.; Lier, P.A.C. van; Crijnen, A.A.M.

    2009-01-01

    Background/Aims: Symptoms of attention deficit hyperactivity disorder (ADHD) have often been associated with early-onset smoking. We hypothesize that reductions in ADHD symptoms due to an intervention have a mediating effect on early-onset smoking. Methods: In a universal, school-based, randomized

  2. Attention deficit hyperactivity disorder symptoms mediate early-onset smoking

    NARCIS (Netherlands)

    A.C. Huizink (Anja); P.A.C. van Lier (Pol); A.A.M. Crijnen (Alfons)

    2008-01-01

    textabstractBackground/Aims: Symptoms of attention deficit hyperactivity disorder (ADHD) have often been associated with early-onset smoking. We hypothesize that reductions in ADHD symptoms due to an intervention have a mediating effect on early-onset smoking. Methods: In a universal, school-based,

  3. Potential for waste reduction

    International Nuclear Information System (INIS)

    Warren, J.L.

    1990-01-01

    The author focuses on wastes considered hazardous under the Resource Conservation and Recovery Act. This chapter discusses wastes that are of interest as well as the factors affecting the quantity of waste considered available for waste reduction. Estimates are provided of the quantities of wastes generated. Estimates of the potential for waste reduction are meaningful only to the extent that one can understand the amount of waste actually being generated. Estimates of waste reduction potential are summarized from a variety of government and nongovernment sources

  4. Curatorial Acts

    NARCIS (Netherlands)

    Bal, M.

    2012-01-01

    In a self-critical inquiry into my own recent work of co-curating and the experience of seeing my video work being curated by others, this article examines acts of framing as performative acts that seek to transform visitors' preconceptions. This affective effect is pursued by means of immersion,

  5. The congressional viewpoint: Deficit reduction and risk legislation

    Energy Technology Data Exchange (ETDEWEB)

    Chakoff, H.E.

    1995-12-31

    This presentation will provide a current congressional status of legislation related to low-level waste and DOE cleanup. Key legislation discussed will include S. 755 for Privatization of the Uranium Enrichment Corporation and the markup of H.R. 1020, the Nuclear Waste Legislation. In addition, the session will include a discussion of legislation related to the approval of the Texas compact.

  6. The congressional viewpoint: Deficit reduction and risk legislation

    International Nuclear Information System (INIS)

    Chakoff, H.E.

    1995-01-01

    This presentation will provide a current congressional status of legislation related to low-level waste and DOE cleanup. Key legislation discussed will include S. 755 for Privatization of the Uranium Enrichment Corporation and the markup of H.R. 1020, the Nuclear Waste Legislation. In addition, the session will include a discussion of legislation related to the approval of the Texas compact

  7. Pragmatic communication deficits in children with epilepsy

    NARCIS (Netherlands)

    Broeders, Mark; Geurts, Hilde; Jennekens-Schinkel, Aag

    2010-01-01

    Background: Various psychiatric and neurological disorders including epilepsy have been associated with language deficits. Pragmatic language deficits, however, have seldom been the focus of earlier studies in children with epilepsy. Moreover, it is unknown whether these pragmatic deficits are

  8. ACT Test

    Science.gov (United States)

    ... to clot, the higher the degree of clotting inhibition. During surgery, the ACT is kept above a ... What is ECLS? An Introduction to Extracorporeal Life Support. University of Michigan Health System [On-line information]. ...

  9. Reduction redux.

    Science.gov (United States)

    Shapiro, Lawrence

    2018-04-01

    Putnam's criticisms of the identity theory attack a straw man. Fodor's criticisms of reduction attack a straw man. Properly interpreted, Nagel offered a conception of reduction that captures everything a physicalist could want. I update Nagel, introducing the idea of overlap, and show why multiple realization poses no challenge to reduction so construed. Copyright © 2017 Elsevier Ltd. All rights reserved.

  10. The Effect of Karate Techniques Training on Communication Deficit of Children with Autism Spectrum Disorders.

    Science.gov (United States)

    Bahrami, Fatimah; Movahedi, Ahmadreza; Marandi, Sayed Mohammad; Sorensen, Carl

    2016-03-01

    This investigation examined the long term effect of Karate techniques training on communication of children with autism spectrum disorders (ASD). Thirty school aged children with ASD were randomly assigned to an exercise (n = 15) or a control group (n = 15). Participants in the exercise group were engaged in 14 weeks of Karate techniques training. Communication deficit at baseline, post-intervention (week 14), and at 1 month follow up were evaluated. Exercise group showed significant reduction in communication deficit compared to control group. Moreover, reduction in communication deficit in the exercise group at one month follow up remained unchanged compared to post-intervention time. We concluded that teaching Karate techniques to children with ASD leads to significant reduction in their communication deficit.

  11. A Proper Perspective on the Twin Deficits

    Science.gov (United States)

    1989-05-01

    deficit twins, the relation between them, and their consanguine parentage. The trade deficit or, to be more accurate, the current account deficit, is...In general, there is a small negative, but statistically significant, relationship between the size of the federal deficit in one year and the

  12. PRAGMATIC DEFICITS OF ASPERGER SYNDROME

    Directory of Open Access Journals (Sweden)

    Silmy Arizatul Humaira’

    2015-08-01

    Full Text Available Human being is social creature who needs other people to interact with. One of the ways to interact with others is communication with language. However, communication could be a complicated problem for those who were born with developmental disorder called Asperger Syndrome (AS. The communication challenge of Asperger’s is the difficulty using language appropriately for social purposes or known as pragmatic deficits. Many excellent books about autism are published whereas knowledge on pragmatic deficits are still very limited. Thus, it is expected to be a beneficial reference to understand the pragmatic deficits and to create strategies for them to communicate effectively. Therefore, this study aimed at exploring the kinds of pragmatic deficits of an individual with AS. The verbal language profiles of autism purposed by MacDonald (2004 is used to analyzed the data in depth. The descriptive qualitative method is applied to develop a comprehensive understanding about the AS case in Temple Grandin movie.The finding shows that all of the five types of communication deficits are appearing and the dominant of which is unresponsive.

  13. Automatic Deficits can lead to executive deficits in ADHD

    Directory of Open Access Journals (Sweden)

    Gabriella Martino

    2017-12-01

    Full Text Available It has been well documented an executive dysfunction in children with Attention Deficit Hyperactivity Disorder (ADHD and with Reading Disorder (RD. The purpose of the present study was to test an alternative hypothesis that deficits in executive functioning within ADHD may be partially due to an impairment of the automatic processing. In addition, since the co-occurrence between ADHD and RD, we tested the hypothesis that the automatic processing may be  a possible common cognitive factor between ADHD and RD. We investigated the automatic processing of selective visual attention through two experiments. 12 children with ADHD, 17 with ADHD+RD and 29 typically developing children, matched for age and gender, performed two tasks: Visual Information Processing Task and Clock Test. As expected, ADHD and ADHD+RD groups differed from the control group in controlled process task, suggesting a deficit in executive functioning. All clinical subjects also exhibited a lower performance in automatic processes, compared to control group. The results of this study suggest that executive deficits within ADHD can be partially due to an impairment of automatic processing.

  14. Widespread auditory deficits in tune deafness.

    Science.gov (United States)

    Jones, Jennifer L; Zalewski, Christopher; Brewer, Carmen; Lucker, Jay; Drayna, Dennis

    2009-02-01

    than the normal control group. Approximately one-third of our participants with tune deafness displayed evidence of attention deficit with hyperactivity disorder on the Test of Variables of Attention. Test of Variables of Attention scores were significantly correlated with gap-detection scores, but not significantly correlated with any of the other experimental measures, including the DTT, DLF, and auditory pattern discrimination tests. Short- and long-term memory was not significantly related to any of the experimental measures. Individuals with tune deafness identified by the DTT have poor performance on many tests of auditory function. These include pure-tone frequency discrimination, pitch and duration pattern discrimination, and temporal resolution. Overall, reduction in performance does not seem to derive from deficits in memory or attention. However, because of the prevalence of attention deficit with hyperactivity disorder in those with tune deafness, this variable should be considered as a potentially confounding factor in future studies of tune deafness and its characteristics. Pure-tone frequency discrimination varied widely in individuals with tune deafness, and the high degree of intertrial variability suggests that frequency discrimination may be unstable in tune-deaf individuals.

  15. Attention Deficit Hyperactivity Disorder (ADHD)

    Centers for Disease Control (CDC) Podcasts

    2014-04-10

    This podcast discusses Attention Deficit Hyperactivity Disorder, or ADHD, the most common behavioral disorder in children. Learn about symptoms, risk factors, and treatment.  Created: 4/10/2014 by National Center on Birth Defects and Developmental Disabilities (NCBDDD).   Date Released: 5/7/2014.

  16. Rhythm Deficits in "Tone Deafness"

    Science.gov (United States)

    Foxton, Jessica M.; Nandy, Rachel K.; Griffiths, Timothy D.

    2006-01-01

    It is commonly observed that "tone deaf" individuals are unable to hear the beat of a tune, yet deficits on simple timing tests have not been found. In this study, we investigated rhythm processing in nine individuals with congenital amusia ("tone deafness") and nine controls. Participants were presented with pairs of 5-note sequences, and were…

  17. Neurocognitive impairment in deficit and non-deficit schizophrenia: a meta-analysis.

    Science.gov (United States)

    Bora, E; Binnur Akdede, B; Alptekin, K

    2017-10-01

    Most studies suggested that patients with deficit schizophrenia have more severe impairment compared with patients with non-deficit schizophrenia. However, it is not clear whether deficit and non-deficit schizophrenia are associated with differential neurocognitive profiles. The aim of this meta-analytic review was to compare cognitive performances of deficit and non-deficit patients with each other and with healthy controls. In the current meta-analysis, differences in cognitive abilities between 897 deficit and 1636 non-deficit patients with schizophrenia were examined. Cognitive performances of 899 healthy controls were also compared with 350 patients with deficit and 592 non-deficit schizophrenia. Both deficit (d = 1.04-1.53) and non-deficit (d = 0.68-1.19) schizophrenia were associated with significant deficits in all cognitive domains. Deficit patients underperformed non-deficit patients in all cognitive domains (d = 0.24-0.84) and individual tasks (d = 0.39-0.93). The relationship between deficit syndrome and impairment in olfaction, social cognition, verbal fluency, and speed-based cognitive tasks were relatively stronger. Our findings suggest that there is consistent evidence for a significant relationship between deficit syndrome and more severe cognitive impairment in schizophrenia.

  18. Perception in attention deficit hyperactivity disorder

    NARCIS (Netherlands)

    Fuermaier, Anselm B.M.; Hüpen, Philippa; De Vries, Stefanie M.; Müller, Morgana; Kok, Francien M.; Koerts, Janneke; Heutink, Joost; Tucha, Lara; Gerlach, Manfred; Tucha, Oliver

    A large body of research demonstrated that individuals with attention deficit hyperactivity disorder (ADHD) suffer from various neuropsychological deficits. In contrast, less is known and only divergent evidence exists on perceptual functions of individuals with ADHD. This is problematic as

  19. Focusing on ADHD - Attention Deficit Hyperactivity Disorder

    Science.gov (United States)

    ... September 2014 Print this issue Focusing on ADHD Attention Deficit Hyperactivity Disorder En español Send us your comments ... might be signs of a developmental disorder called attention deficit hyperactivity disorder, or ADHD. ADHD is a common ...

  20. Attention-Deficit Hyperactivity Disorder (ADHD)

    Science.gov (United States)

    ... Tube DysfunctionStrep ThroatAnemiaHyperthyroidismOpioid AddictionDiabetesCroup Home Diseases and Conditions Attention-Deficit Hyperactivity Disorder (ADHD) Condition Attention-Deficit Hyperactivity Disorder ( ...

  1. Adult Attention-Deficit / Hyperactivity Disorder (ADHD)

    Science.gov (United States)

    Adult attention-deficit/hyperactivity disorder (ADHD) Overview Adult attention-deficit/hyperactivity disorder (ADHD) is a mental health disorder that includes a combination of persistent problems, such as difficulty paying attention, ...

  2. Faststats: Attention Deficit Hyperactivity Disorder (ADHD)

    Science.gov (United States)

    ... this? Submit What's this? Submit Button NCHS Home Attention Deficit Hyperactivity Disorder (ADHD)* Recommend on Facebook Tweet Share Compartir Data ... attention deficit disorder (ADD)” is used rather than “attention deficit hyperactivity disorder (ADHD)” in some data sources. More data Tables ...

  3. Pragmatic Communication Deficits in Children with Epilepsy

    Science.gov (United States)

    Broeders, Mark; Geurts, Hilde; Jennekens-Schinkel, Aag

    2010-01-01

    Background: Various psychiatric and neurological disorders including epilepsy have been associated with language deficits. Pragmatic language deficits, however, have seldom been the focus of earlier studies in children with epilepsy. Moreover, it is unknown whether these pragmatic deficits are related to general intellectual functioning. Both…

  4. Water-deficit tolerant classification in mutant lines of indica rice

    Directory of Open Access Journals (Sweden)

    Suriyan Cha-um

    2012-04-01

    Full Text Available Water shortage is a major abiotic stress for crop production worldwide, limiting the productivity of crop species, especially in dry-land agricultural areas. This investigation aimed to classify the water-deficit tolerance in mutant rice (Oryza sativa L. spp. indica genotypes during the reproductive stage. Proline content in the flag leaf of mutant lines increased when plants were subjected to water deficit. Relative water content (RWC in the flag leaf of different mutant lines dropped in relation to water deficit stress. A decrease RWC was positively related to chlorophyll a degradation. Chlorophyll a , chlorophyll b , total chlorophyll , total carotenoids , maximum quantum yield of PSII , stomatal conductance , transpiration rate and water use efficiency in mutant lines grown under water deficit conditions declined in comparison to the well-watered, leading to a reduction in net-photosynthetic rate. In addition, when exposed to water deficit, panicle traits, including panicle length and fertile grains were dropped. The biochemical and physiological data were subjected to classify the water deficit tolerance. NSG19 (positive control and DD14 were identified as water deficit tolerant, and AA11, AA12, AA16, BB13, BB16, CC12, CC15, EE12, FF15, FF17, G11 and IR20 (negative control as water deficit sensitive, using Ward's method.

  5. Comparison of duloxetine and methylphenidate in the treatment of children with attention-deficit/hyperactivity disorder

    Directory of Open Access Journals (Sweden)

    Nasrin Dodangi

    2016-06-01

    Full Text Available Background: Attention-deficit/hyperactivity disorder (ADHD is a common and mostly chronic mental health condition that affects children, adolescents, and adults. Stimulants and atomoxetine are first-line agents for the treatment of ADHD. Despite the impressive track record of stimulants in the treatment of ADHD, they fail in 25% of patients due to lack of efficacy or the emergence of unwanted side effects. Accordingly, this study carried out to compare efficacy and safety of duloxetine (a serotonin and norepinephrine reuptake inhibitor and methylphenidate (a short acting stimulant in the treatment of children with attention-deficit/hyperactivity disorder. Methods: Twenty-four children diagnosed with ADHD participated in this 6 weeks open clinical trial. Patients were between 6 to 11 years old that had been referred to psychiatry clinic at Akhavan and Rofide Medical and Rehabilitation Center in Tehran from September 2012 to July 2014. Diagnosis was made by two child psychiatrist according to DSM-IV TR criteria. Thirteen patients received duloxetine and others received methylphenidate. Conner’ parent rating scale-revised-short form (CPRS-RS and ADHD-rating scale (ADHD-RS were used at the beginning and then each two weeks to assess efficacy of treatment. Routine laboratory tests and electrocardiogram (ECG was carried out in the beginning and end of the trial. Results: Twenty children with ADHD completed the study (Ten in methylphenidate and ten in duloxetine group. In both groups, scales of CPRS-RS and ADHD-RS were reduced from baseline to endpoint, but this reduction in methylphenidate group was significantly greater than duloxetine group (P= 0.000. The most common side effect was gastrointestinal problems in duloxetine group and anorexia in methylphenidate group. No serious side effects and no changes in laboratory and ECG indexes were seen in both groups. Conclusion: Duloxetine is not efficacious as well as methylphenidate in treatment of

  6. Reduction corporoplasty.

    Science.gov (United States)

    Hakky, Tariq S; Martinez, Daniel; Yang, Christopher; Carrion, Rafael E

    2015-01-01

    Here we present the first video demonstration of reduction corporoplasty in the management of phallic disfigurement in a 17 year old man with a history sickle cell disease and priapism. Surgical management of aneurysmal dilation of the corpora has yet to be defined in the literature. We preformed bilateral elliptical incisions over the lateral corpora as management of aneurysmal dilation of the corpora to correct phallic disfigurement. The patient tolerated the procedure well and has resolution of his corporal disfigurement. Reduction corporoplasty using bilateral lateral elliptical incisions in the management of aneurysmal dilation of the corpora is a safe an feasible operation in the management of phallic disfigurement.

  7. Brain and behavioural correlates of action semantic deficits in autism.

    Directory of Open Access Journals (Sweden)

    Rachel Louise Moseley

    2013-11-01

    Full Text Available Action-perception circuits comprising neurons in the motor system have been proposed as main building blocks of higher cognition; accordingly, motor dysfunction should entail cognitive deficits. Autism spectrum conditions (ASC are marked by motor impairments but the implications of such motor dysfunction for higher cognition remain unclear. We here used word reading and semantic judgement tasks to interrogate action-related motor cognition and its corresponding fMRI brain activation in high-functioning adults with ASC. These participants exhibited hypoactivity of motor cortex in language processing relative to typically developing (TD controls. Crucially, we also found a deficit in semantic processing of action-related words, which, intriguingly, significantly correlated with their underactivation of motor cortex to these items. Furthermore, the word-induced hypoactivity in the motor system also predicted the severity of ASC as expressed by the number of autistic symptoms measured by the Autism-Spectrum Quotient (Baron-Cohen et al, 2001. These significant correlations between word-induced activation of the motor system and a newly discovered semantic deficit in a condition known to be characterised by motor impairments, along with the correlation of such activation with general autistic traits confirm critical predictions of causal theories explaining cognitive and semantic deficits in ASC, in part, to dysfunctional action-perception circuits and resultant reduction of motor system activation.

  8. Attention-deficit hyperactivity disorder.

    Science.gov (United States)

    Meek, D C

    1990-09-01

    The attention-deficit hyperactivity disorder is a common chronic disorder of childhood. No precise definition or approach to treatment is universally accepted; however, an extensive literature exists on which to base a rational approach to management. Symptomatic treatment with stimulant medication in selected patients is effective and safe, but not curative. Successful outcome depends on multimodality therapy, involving parents, teachers, and other professionals. Associated conditions, including learning disorders and emotional disturbance, must be identified and dealt with.

  9. Unraveling the involvement of ABA in the water deficit-induced modulation of nitrogen metabolism in Medicago truncatula seedlings.

    Science.gov (United States)

    Planchet, Elisabeth; Rannou, Olivier; Ricoult, Claudie; Limami, Anis M

    2011-07-01

    Effects of water deficit and/or abscisic acid (ABA) were investigated on early seedling growth of Medicago truncatula, and on glutamate metabolism under dark conditions. Water deficit (simulated by polyethylene glycol, PEG), ABA and their combination resulted in a reduction in growth rate of the embryo axis, and also in a synergistic increase of free amino acid (AA) content. However, the inhibition of water uptake retention induced by water deficit seemed to occur in an ABA-independent manner. Expression of several genes involved in glutamate metabolism was induced during water deficit, whereas ABA, in combination or not with PEG, repressed them. The only exception came from a gene encoding 1-pyrroline-5-carboxylate synthetase (P5CS) which appeared to be induced in an ABA-dependent manner under water deficit. Our results demonstrate clearly the involvement of an ABA-dependent and an ABA-independent regulatory system, governing growth and glutamate metabolism under water deficit.

  10. 78 FR 661 - Waiver From Rescission of Unobligated Funds Under the American Recovery and Reinvestment Act of 2009

    Science.gov (United States)

    2013-01-04

    ... Fund Symbol codes and names, not to exceed the amounts stated: Department of Defense: 97-0501--Military... deficit reduction and prohibited from use as an offset for other spending increases or revenue reductions...

  11. Association between the attention deficits and delinquency

    Directory of Open Access Journals (Sweden)

    Robert Opora

    2011-12-01

    Full Text Available In the society we can find a lot of prejudices concerning AD/HD. The article contains facts and evidence based on research presenting that the delinquency is very often a distant complication of attention deficits but it doesn’t mean that a child with attention deficits has to be delinquent. The article describes the association between the attention deficits and delinquency. There are presented some risk factors coming from the attention deficits and protective factors which let the child follow the social norms. The research was based on 108 delinquent juveniles staying under the probation supervision. The purpose of the research was to evaluate the frequency of the attention deficits among delinquent juveniles staying under supervision. The research findings concern also the association between the attention deficit and external behavioural disorders. In the summary several conditions are described which are important to protect children with attention deficit from delinquency.

  12. TANZANIA'S 2002 RECORDS AND ARCHIVES MANAGEMENT ACT

    African Journals Online (AJOL)

    However, some critical areas that need serious revisiting include supporting the Act with adequate resources, training, provisions on electronic records and records created by Union Government. The paper recommends facilitation of ample resources, training on the Act, reduction of power of director of the Records and ...

  13. Reduction Corporoplasty

    Directory of Open Access Journals (Sweden)

    Tariq S. Hakky

    2015-04-01

    Full Text Available Objective Here we present the first video demonstration of reduction corporoplasty in the management of phallic disfigurement in a 17 year old man with a history sickle cell disease and priapism. Introduction Surgical management of aneurysmal dilation of the corpora has yet to be defined in the literature. Materials and Methods: We preformed bilateral elliptical incisions over the lateral corpora as management of aneurysmal dilation of the corpora to correct phallic disfigurement. Results The patient tolerated the procedure well and has resolution of his corporal disfigurement. Conclusions Reduction corporoplasty using bilateral lateral elliptical incisions in the management of aneurysmal dilation of the corpora is a safe an feasible operation in the management of phallic disfigurement.

  14. Current pharmacotherapy of attention deficit hyperactivity disorder.

    Science.gov (United States)

    Reddy, D S

    2013-10-01

    Attention deficit hyperactivity disorder (ADHD) is a neurobehavioral developmental disorder in children and adults characterized by a persistent pattern of impulsiveness, inattention and hyperactivity. It affects about 3-10% of children and 2-5% of adolescents and adults and occurs about four times more commonly in boys than girls. The cause of ADHD is unknown, but it has strong genetic and environment components. The first-line treatment options for ADHD include behavioral therapy, pharmacotherapy with stimulants or both. Methylphenidate and amphetamine salts are the stimulant drugs of choice for ADHD treatment. Amphetamines act by increasing presynaptic release of dopamine and other biogenic amines in the brain. Methylphenidate inhibits the reuptake of dopamine and norepinephrine and therefore its pharmacology is identical to that of amphetamines. Lisdex-amfetamine is a prodrug of dextroamphetamine with low feasibility for abuse. Atomoxetine, a selective norepinephrine reuptake inhibitor, is an alternative, non-stimulant drug for ADHD but it is less efficacious than stimulants. Stimulants are generally safe but are associated with adverse effects including headache, insomnia, anorexia and weight loss. There is increased awareness about serious cardiovascular and psychiatric adverse events with ADHD drugs including concern for growth suppression in children. Stimulants have a high potential for abuse and dependence, and should be handled safely to prevent misuse and abuse. Copyright 2013 Prous Science, S.A.U. or its licensors. All rights reserved.

  15. Special Education for Children with Attention Deficit Disorder: Current Issues. CRS Report for Congress.

    Science.gov (United States)

    Aleman, Steven R.

    This paper examines issues concerning the eligibility of children with attention deficit disorder (ADD) for special education and related services under the Individuals with Disabilities Education Act (IDEA). A policy memorandum was issued by the Department of Education in September 1991, identifying those circumstances under which such children…

  16. A Controlled Trial of Extended-Release Guanfacine and Psychostimulants for Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Wilens, Timothy E.; Bukstein, Oscar; Brams, Matthew; Cutler, Andrew J.; Childress, Ann; Rugino, Thomas; Lyne, Andrew; Grannis, Kara; Youcha, Sharon

    2012-01-01

    Objective: To examine efficacy, tolerability, and safety of guanfacine extended release (GXR; less than or equal to 4 mg/d) adjunctive to a long-acting psychostimulant for the treatment of attention-deficit/hyperactivity disorder (ADHD) in children and adolescents 6 to 17 years of age with suboptimal, but partial, response to psychostimulant…

  17. Snubber reduction

    International Nuclear Information System (INIS)

    Olson, D.E.; Singh, A.K.

    1986-01-01

    Many safety-related piping systems in nuclear power plants have been oversupported. Since snubbers make up a large percentage of the pipe supports or restraints used in a plant, a plant's snubber population is much larger than required to adequately restrain the piping. This has resulted in operating problems and unnecessary expenses for maintenance and inservice inspections (ISIs) of snubbers. This paper presents an overview of snubber reduction, including: the incentives for removing snubbers, a historical perspective on how piping became oversupported, why it is possible to remove snubbers, and the costs and benefits of doing so

  18. Budget Deficits Effects on Economic Growth

    Directory of Open Access Journals (Sweden)

    L.C.Risti

    2013-06-01

    Full Text Available The budget deficit can not be analyzed autarchically, as it affects all the macroeconomic processes and, is itself influenced by all other macroeconomic indicators. Most analyses and studies on public finance and budget balance measure the impact that budgetary deficits accumulation has on economy. Therefore, the present paper aims at following and analyzing the mutual impact between budget deficit and another economic macro indicator, namely the economic growth.

  19. Neurocognitive Deficits in Borderline Personality Disorder

    DEFF Research Database (Denmark)

    Thomsen, Marianne Skovgaard; Ruocco, Anthony C; Carcone, Dean

    2017-01-01

    completed a comprehensive battery of neurocognitive tests, a retrospective questionnaire on early life trauma and a dimensional measure of personality psychopathology. Patients with BPD primarily showed deficits in verbal comprehension, sustained visual attention, working memory and processing speed...... suggest that patients with BPD display deficits mainly in higher-order thinking abilities that may be exacerbated by PTSD and substantial early life trauma. Potential relationships between neurocognitive deficits and dimensions of personality psychopathology in BPD need further examination....

  20. Radon reduction

    International Nuclear Information System (INIS)

    Hamilton, M.A.

    1990-01-01

    During a radon gas screening program, elevated levels of radon gas were detected in homes on Mackinac Island, Mich. Six homes on foundations with crawl spaces were selected for a research project aimed at reducing radon gas concentrations, which ranged from 12.9 to 82.3 pCi/l. Using isolation and ventilation techniques, and variations thereof, radon concentrations were reduced to less than 1 pCi/l. This paper reports that these reductions were achieved using 3.5 mil cross laminated or 10 mil high density polyethylene plastic as a barrier without sealing to the foundation or support piers, solid and/or perforated plastic pipe and mechanical fans. Wind turbines were found to be ineffective at reducing concentrations to acceptable levels. Homeowners themselves installed all materials

  1. Atomic Energy Commission Act, 2000 (Act 588)

    International Nuclear Information System (INIS)

    2000-01-01

    Act 588 of the Republic of Ghana entitled, Atomic Energy Commission Act, 2000, amends and consolidates the Atomic Energy Commission Act, 204 of 1963 relating to the establishment of the Atomic Energy Commission. Act 588 makes provision for the Ghana Atomic Energy Commission to establish more institutes for the purpose of research in furtherance of its functions and also promote the commercialization of its research and development results. (E.A.A.)

  2. The deficit of current account balances and budgetary deficit in countries in transition

    OpenAIRE

    Sandra Krtalic; Ines Kersan

    1998-01-01

    In restructuring process of their own economies, countries in transition deal with many common problems. One of the problems that transition brought to those countries is deficit in current account, as well as budget deficit. Deficits represent limit to a healthy and fast economic development and progress. Balance in balance of payments, as well as balanced budget are components of macroeconomic system. The authors will give an review of activities on deficits in countries in transition, and ...

  3. Adults with attention-deficit/hyperactivity disorder - a brain magnetic resonance spectroscopy study

    DEFF Research Database (Denmark)

    Dramsdahl, Margaretha; Ersland, Lars; Plessen, Kerstin J

    2011-01-01

    Background: Impaired cognitive control in individuals with attention-deficit/hyperactivity disorder (ADHD) may be related to a prefrontal cortical glutamatergic deficit. We assessed the glutamate level in the left and the right midfrontal region including the anterior cingulate cortex in adults...... groups. Results: The ADHD group showed a significant reduction of Glu/Cre in the left midfrontal region compared to the controls. Conclusion: The reduction of Glu/Cre in the left midfrontal region in the ADHD group may reflect a glutamatergic deficit in prefrontal neuronal circuitry in adults with ADHD...... with ADHD and healthy controls. Methods: Twenty-nine adults with ADHD and 38 healthy controls were included. We used Proton Magnetic Resonance Imaging with single voxel point-resolved spectroscopy to measure the ratio of glutamate to creatine (Glu/Cre) in the left and the right midfrontal region in the two...

  4. Detection of neurological deficits by computed tomography in sacral fracture patients

    International Nuclear Information System (INIS)

    Nakai, Daisuke; Numazaki, Shin; Katsumura, Tetsu; Tamaru, Tomohiko; Sugiyama, Mitsugi; Nakamura, Jun-ichiro; Saitoh, Tomoyuki

    2006-01-01

    The purpose of this study is to evaluate the correlation between sacral fractures and neurological deficits as complications. From November 2002 to February 2005, 12 patients (15 fractures) were found to have sacral fractures without other spinal injuries or brain injuries and were evaluated by plain CT scans immediately after trauma. This group included 6 males and 6 females, whose age ranged from 17 to 67 years with mean of 39.9±17.4. All patients were classified according to AO (Arbeitsgemeinschaft fuer Osteosynthesefragen) classification (pelvic ring fracture) and Denis's classification. Displacements of sacral fractures were evaluated by plain CT scans for all patients. We defined displacements using the key slice in CT scans that included the first foramen in the sacrum. Five cases, including 2 with bi-lateral sacral fractures, were complicated with neurological deficits. There was one case with a neurological deficit of 7 Type B fractures (14%) and 4 cases with neurological deficits of 5 Type C fractures (80%) in the AO classification. There were 6 fractures with neurological deficits of 12 Zone II fractures (50%) and one fracture with neurological deficits of one Zone III fractures (100%) in Denis's classification. There was a significant correlation between the extent in the displacement of the sacral fractures and neurological deficits. For more than 3 mm displacements in the medial or lateral or anterior directions, neurological deficits increased significantly. In emergency medicine, it is difficult to evaluate the neurological findings of patients with impaired consciousness. Our evaluation using CT scan is valuable as a predictor of neurological deficits and for an optimal reduction in sacral fractures in patients with in impaired consciousness. (author)

  5. [Nutritional aspects of attention-deficit/hyperactive disorder].

    Science.gov (United States)

    Quintero, J; Rodríguez-Quirós, J; Correas-Lauffer, J; Pérez-Templado, J

    Attention-deficit/hyperactive disorder (ADHD) has received in the past years a lot of attention from the paediatrician's specialties. Even though the studies of its etiopathology have advanced, mainly the ones related with genetics and neuroimaging, the final cause today is still unclear. It has been related to many factors such as diet, like some allergies to additives, toxicity to heavy metals and other toxic substances from the environment, due to low protein diets with a high carbohydrate content, unbalanced minerals, essential fatty acids and phospholipid deficit, amino acid deficits, thyroid disorders, and vitamin B complex disorders and phytochemicals. The way our lifestyle has changed in general and the diet in particular nowadays is being considered as a hypothesis for many disorders and health problems, but what about ADHD? One of the changes that we want to emphasize is related to vegetable fat and oils that dominate human consumption and the reduction income of fatty acids from the omega-3 family, including alpha-linolenic acid, eicosapentaenoic acid and docosapentaenoic acid. The fact is even worse when the amount of omega-6 increases and the ratio between both changes. It is a fact that these kinds of nutrients play an important role in the nervous system development. In this paper the essential fatty acids in neuropsychiatric disorders in general, ADHD in particular, is reviewed.

  6. Measuring Working Memory Deficits in Aphasia

    Science.gov (United States)

    Mayer, Jamie F.; Murray, Laura L.

    2012-01-01

    Purpose: Many adults with aphasia demonstrate concomitant deficits in working memory (WM), but such deficits are difficult to quantify because of a lack of validated measures as well as the complex interdependence between language and WM. We examined the feasibility, reliability, and internal consistency of an "n"-back task for…

  7. Traumatic brain injury and olfactory deficits

    DEFF Research Database (Denmark)

    Fortin, Audrey; Lefebvre, Mathilde Beaulieu; Ptito, Maurice

    2010-01-01

    . Between 40-44% of the patients showing olfactory impairments were not aware of their deficit. CONCLUSIONS: Since a significant proportion of the patients showing olfactory impairments were not aware of their deficit, it is recommended than clinicians systematically evaluate olfactory functions using...

  8. Neurologic deficit after resection of the sacrum.

    Science.gov (United States)

    Biagini, R; Ruggieri, P; Mercuri, M; Capanna, R; Briccoli, A; Perin, S; Orsini, U; Demitri, S; Arlecchini, S

    1997-01-01

    The authors describe neurologic deficit (sensory, motor, and sphincteral) resulting from sacrifice of the sacral nerve roots removed during resection of the sacrum. The anatomical and functional bases of sphincteral continence and the amount of neurologic deficit are discussed based on level of sacral resection. A large review of the literature on the subject is reported and discussed. The authors emphasize how the neurophysiological bases of sphincteral continence (rectum and bladder) and of sexual ability are still not well known, and how the literature reveals disagreement on the subject. A score system is proposed to evaluate neurologic deficit. The clinical model of neurologic deficit caused by resection of the sacrum may be extended to an evaluation of post-traumatic deficit.

  9. Effect of Deficit Irrigation Treatments on Vegetative Characteristics and Quantity and Quality of Golden Delicious Apple

    Directory of Open Access Journals (Sweden)

    I. Arji

    2016-07-01

    Full Text Available Introduction: Since Iran is located in arid and semi-arid region of the world, so consumption and saving of water must be taking into account. Water is often a valuable natural resource, thus proper application methods - for increase water efficiency can be very important. Regulated deficit irrigation (RDI is one of the most important methods to increase water use efficiency and fruit quality. Apple is one of the most important fruit trees from economical point of view. Studies showed that regulated deficit irrigation led to growth reduction in apple trees and sometimes fruit quality increased. The aim of this study was to evaluate the effect deficit irrigation on vegetative growth and fruit quantity and quality of Golden delicious apple trees in Gahvareh region of Kermanshah province. Materials and Methods: This experiment was conducted on 10 years old Golden delicious apple trees in a randomized complete block design with 5 irrigation treatments and three replications during 2006. Three apple trees assigned to each experimental unit. Irrigation treatments were: T1= early deficit irrigation (40% water requirement, T2= early deficit irrigation (60% water requirement, T3= late deficit irrigation (40% water requirement, T4=late deficit irrigation (60% water requirement, T5=control (C (100% water requirement. Early deficit irrigation starts 55 days after full bloom (15th Jun and continued 60 days (16th Aug, while late deficit irrigation starts 115 days after from full bloom (16th Aug and continued 40 days near to harvesting time (23th Sept. Control trees were full irrigated based on water requirement, which calculated based on national water document of Iran and irrigation amount was calculated based on the following formulas: Q=0.0184.L.H3/2 Where Q is volumetric flow rate (liter/Second, L is parshall flume crown length (cm and H is water height (cm. Irrigation time was calculated based on national water document of Iran and volumetric flow rate

  10. Relationships Between Functional Outcomes and Symptomatic Improvement in Atomoxetine-Treated Adult Patients with Attention-Deficit/Hyperactivity Disorder: Post Hoc Analysis of an Integrated Database

    NARCIS (Netherlands)

    Bruyckere, K. De; Bushe, C.; Bartel, C.; Berggren, L.; Kan, C.C.; Dittmann, R.W.

    2016-01-01

    BACKGROUND: Atomoxetine treatment is associated with improvements in functional outcomes in patients with attention-deficit/hyperactivity disorder (ADHD), although relationships between improvements in these outcomes and reductions in ADHD symptoms have not been comprehensively investigated in

  11. Source-sink relationships in two soybean cultivars with indeterminate growth under water deficit

    Directory of Open Access Journals (Sweden)

    Alexandre José da Silva

    Full Text Available Abstract Water deficit is a major factor limiting crop yield in rainfed areas. We hypothesized that under water deficit the decrease of photosynthetic production stimulates: carbohydrate remobilization from leaves, stems and roots to reproductive organs; and decreasing flowering intensity and pod development. The present work aims to study the effect of water deficit during bloom and grain pod-filling stages in two indeterminate soybean cultivar, Vtop and Nidera. The following physiological parameters were evaluated by means of daily CO2 assimilation rate (Ai, dynamic of carbohydrates in tissues, plant growth, grain yield and yield components. The study was conducted in a greenhouse with plants sown in tanks of 0.5 m3. Regardless of the phenological phase, water deficit reduced Ai, plant growth and number of pods and seeds per plant. The fact that grain yield was less affected by water deficit at bloom than at grain pod-filling stage was attributed to larger seeds found at bloom. In both treatments, a sharp reduction on carbohydrate content was found in leaves, stem and roots at the beginning of pod formation. The high amounts of carbohydrates remobilized for seed growth, along with the high values of Ai observed in well-watered plants, indicate that grain yield of soybeans is source rather than sink limited. On the other hand, in water deficit treatments, a new stimulus for carbohydrate storage was found in the leaves and stem at the beginning of grain maturity, suggesting that grain yield was limited by sink capacity.

  12. Nuclear Regulatory Authority Act, 2015 (Act 895)

    International Nuclear Information System (INIS)

    2015-04-01

    An Act to establish a Nuclear Regulatory Authority in Ghana. This Act provides for the regulation and management of activities and practices for the peaceful use of nuclear material or energy, and to provide for the protection of persons and the environment against the harmful effects of radiation; and to ensure the effective implementation of the country’s international obligations and for related matters. This Act replaced the Radiation Protection Instrument, of 1993 (LI 1559).

  13. Dissociations between developmental dyslexias and attention deficits

    Science.gov (United States)

    Lukov, Limor; Friedmann, Naama; Shalev, Lilach; Khentov-Kraus, Lilach; Shalev, Nir; Lorber, Rakefet; Guggenheim, Revital

    2014-01-01

    We examine whether attention deficits underlie developmental dyslexia, or certain types of dyslexia, by presenting double dissociations between the two. We took into account the existence of distinct types of dyslexia and of attention deficits, and focused on dyslexias that may be thought to have an attentional basis: letter position dyslexia (LPD), in which letters migrate within words, attentional dyslexia (AD), in which letters migrate between words, neglect dyslexia, in which letters on one side of the word are omitted or substituted, and surface dyslexia, in which words are read via the sublexical route. We tested 110 children and adults with developmental dyslexia and/or attention deficits, using extensive batteries of reading and attention. For each participant, the existence of dyslexia and the dyslexia type were tested using reading tests that included stimuli sensitive to the various dyslexia types. Attention deficit and its type was established through attention tasks assessing sustained, selective, orienting, and executive attention functioning. Using this procedure, we identified 55 participants who showed a double dissociation between reading and attention: 28 had dyslexia with normal attention and 27 had attention deficits with normal reading. Importantly, each dyslexia with suspected attentional basis dissociated from attention: we found 21 individuals with LPD, 13 AD, 2 neglect dyslexia, and 12 surface dyslexia without attention deficits. Other dyslexia types (vowel dyslexia, phonological dyslexia, visual dyslexia) also dissociated from attention deficits. Examination of 55 additional individuals with both a specific dyslexia and a certain attention deficit found no attention function that was consistently linked with any dyslexia type. Specifically, LPD and AD dissociated from selective attention, neglect dyslexia dissociated from orienting, and surface dyslexia dissociated from sustained and executive attention. These results indicate that

  14. Effectiveness of Manual Therapy and Stretching for Baseball Players With Shoulder Range of Motion Deficits.

    Science.gov (United States)

    Bailey, Lane B; Thigpen, Charles A; Hawkins, Richard J; Beattie, Paul F; Shanley, Ellen

    Baseball players displaying deficits in shoulder range of motion (ROM) are at increased risk of arm injury. Currently, there is a lack of consensus regarding the best available treatment options to restore shoulder ROM. Instrumented manual therapy with self-stretching will result in clinically significant deficit reductions when compared with self-stretching alone. Controlled laboratory study. Shoulder ROM and humeral torsion were assessed in 60 active baseball players (mean age, 19 ± 2 years) with ROM deficits (nondominant - dominant, ≥15°). Athletes were randomly assigned to receive a single treatment of instrumented manual therapy plus self-stretching (n = 30) or self-stretching only (n = 30). Deficits in internal rotation, horizontal adduction, and total arc of motion were compared between groups immediately before and after a single treatment session. Treatment effectiveness was determined by mean comparison data, and a number-needed-to-treat (NNT) analysis was used for assessing the presence of ROM risk factors. Prior to intervention, players displayed significant ( P < 0.001) dominant-sided deficits in internal rotation (-26°), total arc of motion (-18°), and horizontal adduction (-17°). After the intervention, both groups displayed significant improvements in ROM, with the instrumented manual therapy plus self-stretching group displaying greater increases in internal rotation (+5°, P = 0.010), total arc of motion (+6°, P = 0.010), and horizontal adduction (+7°, P = 0.004) compared with self-stretching alone. For horizontal adduction deficits, the added use of instrumented manual therapy with self-stretching decreased the NNT to 2.2 (95% CI, 2.1-2.4; P = 0.010). Instrumented manual therapy with self-stretching significantly reduces ROM risk factors in baseball players with motion deficits when compared with stretching alone. The added benefits of manual therapy may help to reduce ROM deficits in clinical scenarios where stretching alone is

  15. Economical benzene emission reduction

    International Nuclear Information System (INIS)

    Schuetz, R.

    1999-01-01

    Benzene has been classified as a toxic compound under the Canadian Environmental Protection Act. This has prompted the Alberta Energy and Utilities Board (AEUB) to introduce specific reporting and monitoring guidelines for the oil and gas industry regarding excessive benzene emissions. Glycol dehydration units have been determined to be the major single source of benzene emissions causing air and soil pollution. DualTank Corp. has designed a condensation and storage tank unit to enhance emission reduction, odour elimination and liquid recovery from dehydration units. Their newly designed combined tank unit consists of a large, uninsulated surface area for cooling, and an excessive internal volume for increased retention time. The first prototype was installed in December 1998 at an Enerplus Resources Site. The system provides excellent benzene emission reduction and the elimination of odours and visual plumes. Effective January 1, 1999, the petroleum and natural gas industry must either clean up excessive emissions voluntarily or face government imposed regulations, facility shutdowns and/or fines. 1 fig

  16. In science communication, why does the idea of a public deficit always return? How do the shifting information flows in healthcare affect the deficit model of science communication?

    Science.gov (United States)

    Ko, Henry

    2016-05-01

    The healthcare field contains a multitude of opportunities for science communication. Given the many stakeholders dancing together in a multidirectional tango of communication, we need to ask how much does the deficit model apply to the health field? History dictates that healthcare professionals are the holders of all knowledge, and the patients and other stakeholders are the ones that need the scientific information communicated to them. This essay argues otherwise, in part due to the rise of shared decision-making and patients and other stakeholders acting as partners in healthcare. The traditional deficit model in health held that: (1) doctors were experts and patients were consumers, (2) it is impossible for the public to grasp the many disciplines of knowledge in medicine, (3) if experts have trouble keeping up with medical research then the public surely can't keep up, and (4) it is safer for healthcare professionals to communicate to the public using a deficit model. However, with the rise of partnerships with patients in healthcare decision-making, the deficit model might be weakening. Examples of public participation in healthcare decision-making include: (1) crowd-sourcing public participation in systematic reviews, (2) public participation in health policy, (3) public collaboration in health research, and (4) health consumer groups acting as producers of health information. With the challenges to the deficit model in science communication in health, caution is needed with the increasing role of technology and social media, and how these may affect the legitimacy of healthcare information flows away from the healthcare professional. © The Author(s) 2016.

  17. 76 FR 55393 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-09-07

    ... potential short-term and long-term health effects among children who lived in FEMA-provided temporary... adverse health effects among children who resided in Federal Emergency Management Agency (FEMA)-provided.... Proposed Project Children's Health After the Storms (CHATS)--New--National Center for Environmental Health...

  18. 75 FR 41206 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-07-15

    ... in all 50 states, the District of Columbia, Puerto Rico, and the U.S. Virgin Islands. All awardees... funded for four program areas: Tobacco control, diabetes prevention and control, Healthy Communities, and... programs (OMB No. 0920-0601, exp. 5/31/2010) and diabetes prevention and control programs (OMB No. 0920...

  19. 78 FR 60283 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-10-01

    ... Columbia, Puerto Rico, and the Virgin Islands will continue to submit semi-annual progress reports through..., Tobacco Control, Diabetes Prevention and Control, and Behavioral Risk Factor Surveillance System. These... under the DP09-901 cooperative agreement: diabetes prevention and control, state BRFSS activities, and...

  20. 75 FR 3736 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-01-22

    ... Career Development (OWCD), Centers for Disease Control and Prevention (CDC). Background and Brief... activities to professionals worldwide. Employees of hospitals, universities, medical centers, laboratories, State and Federal agencies, and State and local health departments apply for training to learn up-to...

  1. 78 FR 16269 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-03-14

    ...-0017, Expiration 03/31/ 2013)--Revision--Scientific Education and Professional Development Program... activities to professionals worldwide. Employees of hospitals, universities, medical centers, laboratories, state and federal agencies, and state and local health departments apply for training to learn up-to...

  2. 75 FR 25860 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-05-10

    ... notice. Proposed Project Development and Testing of an HIV Prevention Intervention Targeting Black... interventions. Previous research indicates that 20% to 40% of Black MSM also have female sex partners...-American MSMW. The purpose of the proposed study is to develop and pilot-test three novel behavioral...

  3. 75 FR 43987 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-07-27

    ... from infection. This research is being conducted by three sites to pilot test three unique HIV risk... efficacy in reducing HIV risk behaviors. Findings from this research will also contribute knowledge on how...-demographic background, sexual health, substance use, history of incarceration, HIV testing history, self...

  4. 76 FR 17867 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-03-31

    .... Proposed Project Registration of Individuals Displaced by the Hurricanes Katrina and Rita (Pilot Project... objective and credible research, of air quality conditions present in FEMA housing units to guide FEMA...-term study of the health effects among residents if feasible. Formaldehyde testing conducted and...

  5. 78 FR 64942 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-10-30

    ...) a computer-based intervention (CBI) in which patients see short videos of HIV medical providers (not... safer sex; and (3) one-on-one counseling from a prevention specialist if needed. The following data will... risk behavior that are completed before patients see the CBI videos. Patients with detectable viral...

  6. 78 FR 69855 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-11-21

    ... groups, online focus groups, computer-assisted, in-person, or telephone interviews, and online surveys... revision will adjust for screening and recruitment by allocating 20,000 additional respondents, and 667... Public and Special Populations Screening and 20,000 1 2/60 Recruitment. In-depth Interviews (In 67 1 1...

  7. 75 FR 69673 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-11-15

    ... making and for effective and efficient execution of CDC's response activities. Public health partners... impact and implications. Epi-X was specifically designed to provide public health decision-makers at the... Secure Communication Network (Epi-X))--Revision--Office of Public Health Preparedness and Response (OPHPR...

  8. 76 FR 75885 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-12-05

    ... availability of bridge medications, Medicaid re- enrollment processes, and the number of inmates with mental... regarding the capacity of prison facilities to deliver medical and mental health services, NCHS in...) of healthcare services and specialty healthcare services; and the types of of medical, dental, mental...

  9. 76 FR 5378 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-01-31

    ... from each awardee's landscape, history, and culture. Example activities include the cultivation of... health messages through storytelling, audio and video recordings, and printed materials. CDC requests OMB...

  10. 75 FR 22137 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-04-27

    ... conducting research. The type of information requested reflects a diversity of needs. Topics include homecare, orthopedics, physical therapy, rare factor deficiencies, psychosocial issues, blood safety, women's health..., advocacy and research for people and families with hemophilia and other bleeding disorders. The Hemophilia...

  11. 78 FR 9697 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-02-11

    .../28/2012). In 2012, CDC conducted web-based surveys of smokers and non-smokers in the U.S. for... the sample) and behaviors related to non-smokers' encouragement of smokers to quit smoking... smokers and non-smokers in the U.S. were exposed to cumulative Phase 1 and Phase 2 Campaigns and to...

  12. 77 FR 508 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-01-05

    ... survey will be used to estimate the extent to which smokers and non-smokers in the U.S. were exposed to... through on-line questionnaires involving adult smokers and non-smokers in the U.S., ages 18-54... online sampling in the U.S. Respondents who are non-smokers will be recruited from Knowledge Networks...

  13. 78 FR 33095 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-06-03

    ... various sources (including sodium from processed and restaurant foods, sodium inherent in foods, and salt... collection will include an observational component as well as a sub-study designed to refine the accuracy of...

  14. 75 FR 43985 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-07-27

    ... investigators' prior research, approximately 240 dyads of Hispanic adolescents and their primary caregivers (a... adolescents which it currently lacks. Approximately 400 dyads of Hispanic adolescents and their primary caregivers (a total of 800 people), recruited through two high schools in Miami-Dade County, will be screened...

  15. 75 FR 67373 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-11-02

    ... these requests, call the CDC Reports Clearance Officer at (404) 639-5960 or send an e-mail to [email protected] of human disease. The revisions to the ``Application for Permit to Import or Transport Etiologic... day- to-day processing of these forms. The ``Application for Permit to Import or Transport Live Bats...

  16. 78 FR 68451 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-11-14

    ... target population to which generalization will be made, the sampling frame, the sample design (including... for submission for other generic mechanisms that are designed to yield quantitative results. The... insights on perceptions and opinions, but are not statistical surveys that yield quantitative results that...

  17. 76 FR 77835 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-12-14

    ... population to which generalizations will be made, the sampling frame, the sample design (including... for submission for other generic mechanisms that are designed to yield quantitative results. The... and opinions, but are not statistical surveys that yield quantitative results that can be generalized...

  18. 77 FR 61409 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-10-09

    ... population to which generalizations will be made, the sampling frame, the sample design (including... for submission for other generic mechanisms that are designed to yield quantitative results. The... opinions, but are not statistical surveys that yield quantitative results that can be generalized to the...

  19. 78 FR 52770 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-08-26

    ... population to which generalizations will be made, the sampling frame, the sample design (including... for submission for other generic mechanisms that are designed to yield quantitative results. The... opinions, but are not statistical surveys that yield quantitative results that can be generalized to the...

  20. 77 FR 51808 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-08-27

    ... original BioSense application to the BioSense 2.0 application that has new governance, a new organizational structure, and a new process for data submission and management. The Association of State and Territorial... application BioSense Program maintains 3 different types of information collection: (1) contact information...

  1. 78 FR 47699 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-08-06

    ... risk management practices in these non-hospital settings. In a small study, the National Institute for... on research-to-practice principles and will be assisted by a strong network of dental professional... (CDC) publishes a list of information collection requests under review by the Office of Management and...

  2. 77 FR 70780 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-11-27

    ... requirements or power calculations that justify the proposed sample size, the expected response rate, methods... notice. Proposed Project Generic Clearance for the Collection of Qualitative Feedback on Agency Service... Collection of Qualitative Feedback on Agency Service Delivery'' to OMB for approval under the Paperwork...

  3. 77 FR 61406 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-10-09

    ... recruited to diversify the research sample. Data will be collected one time at each mine; this is not a... variety of statistical and qualitative analyses are conducted on the data to obtain conclusions with... emerge. These include safety culture characteristic differences depending on the size of the mine and...

  4. 78 FR 26033 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-05-03

    ... precision requirements or power calculations that justify the proposed sample size, the expected response... Collection of Qualitative Feedback on Agency Service Delivery--NEW--Epidemiology and Analysis Program Office... Clearance for the Collection of Qualitative Feedback on Agency Service Delivery'' to OMB for approval under...

  5. 77 FR 27062 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-05-08

    ... calculations that justify the proposed sample size, the expected response rate, methods for assessing potential... Project NIOSH Generic Clearance for the Collection of Qualitative Feedback on Agency Service Delivery--NEW... Collection Request (Generic ICR): ``Generic Clearance for the Collection of Qualitative Feedback on Agency...

  6. 75 FR 47818 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-08-09

    .... Qualitative data will be collected through student focus groups and teacher interviews. Students will complete.... Informed written consent from parents for each student's participation and informed written assent from... interviews. Students and teachers will be asked about their experiences with the Safe Dates program and ideas...

  7. 77 FR 6802 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-02-09

    ... Prevention (CDC). Background and Brief Description Latinos are the largest and fastest growing ethnic... 2005, and for more than one-half of HIV infections among South American, Cuban, and Mexican-born Latino..., culturally congruent HIV/STD prevention interventions for Latino MSM. The purpose of this project is to test...

  8. 76 FR 2123 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-01-12

    ... control; improving nutrition, physical activity, and food safety; reducing healthcare-associated... planning, response and recovery activities of subsequent emergencies, and fill gaps in knowledge that will...

  9. 76 FR 51982 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-08-19

    ... in a laboratory study to investigate choice strategies based on the dynamic development of cues... critical skill/knowledge gaps identified in mining (MSTTC, 2006). Their report strongly supports the need...

  10. 78 FR 35933 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-06-14

    ... collection strategies, including self- report pre-and post-test instruments for assessing trainee reaction... over three years. The respondents targeted for this study include rank-and-file miners, mine rescue... immersive VR environments for teaching critical mine safety and health skills. To assess learning as a...

  11. 76 FR 29246 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-05-20

    ... barriers to usage in the field, and possible gateways to this behavior change is needed before developing..., occupation, driving behaviors, attitudes & knowledge of policies, and details of prior motor-vehicle crashes...

  12. 77 FR 28881 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-05-16

    ... used to assess changes in knowledge, attitudes, beliefs and behavior regarding cervical cancer... are to: (1) Assess follow-up of women with positive test results and (2) determine provider knowledge...

  13. 76 FR 14020 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-03-15

    ..., adolescent, parent, and family health, well-being, and knowledge, attitude, and behaviors; children with... care; program participation; adoption; and changes in health insurance coverage and experiences. Users...

  14. 77 FR 42314 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-07-18

    ... Assisted Reproductive Technology (ART) Program Reporting System (0920-0556, exp. 9/30/2012)--Revision... estimated number of responding clinics and an increase in the estimated number of responses per respondent... number of data items deemed important to explain variability in success rates across ART programs and...

  15. 77 FR 41790 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-07-16

    ... Assisted Reproductive Technology (ART) Program Reporting System (0920-0556, exp. 9/30/2012)--Revision... estimated number of responding clinics and an increase in the estimated number of responses per respondent... number of data items deemed important to explain variability in success rates across ART programs and...

  16. 75 FR 43988 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-07-27

    ... questions being explored are relevant for understanding how interpersonal communication with members of one... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention [30Day-10-09BC... Project Exploring HIV Prevention Communication Among Black Men Who Have Sex With Men in New York City...

  17. 77 FR 43286 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-07-24

    ... information are broken into nine separate questions (data fields) for computer entry. General information... Questions. Kimberly S. Lane, Deputy Director, Office of Science Integrity, Office of the Associate Director... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention [30-Day-12-0040...

  18. 77 FR 29350 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-05-17

    ... using audio computer assisted self-interview (ACASI). The ACASI interview includes questions about... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention [30Day-12-12EL... Exit Interview 10 1 30/60 Kimberly S. Lane, Deputy Director, Office of Science Integrity, Office of the...

  19. 77 FR 75167 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-12-19

    ... (NACCHO) and Knowledge Networks will disseminate the study results to the public through reports prepared for/by CDC, NACCHO and Knowledge Networks and through peer-reviewed journal articles and related... draw a sample of participants has many advantages. First, because the panel is already recruited...

  20. 78 FR 22886 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-04-17

    ... in national standards for cancer diagnosis, treatment, and coding. These changes will affect the... leukemia. The enhanced data items will support more in-depth analysis of treatment strategies and patient... year. The first report will consist of a single-year file for data that includes diagnosis 12 months...

  1. 77 FR 55478 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-09-10

    ..., obesity, smoking, drug and alcohol use, physical activity, environmental exposures, and diet. NHANES data... studies the relationship between diet, nutrition and health in a representative sample of the United...

  2. 78 FR 9699 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-02-11

    .... However, high quality evidence demonstrating their effectiveness, by way of controlled trials, is lacking. This project will be conducted as a partnership between NIOSH and Toyota Motors Engineering & Manufacturing North America, Inc. (TEMA), with the intervention evaluation study taking place at the Toyota...

  3. 77 FR 40360 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-07-09

    ... Tuberculosis; Smallpox; Yellow fever; and Viral Hemorrhagic Fevers), as well as most communicable diseases in... Death Investigation Forms--Airline, Maritime, Land/Border Crossing Illness and Death Investigation Forms... arrival in the United States. An ``ill person'' is defined in statute by: --Fever (>=100 [deg]F or 38 [deg...

  4. 77 FR 72867 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-12-06

    ... cancer, diabetes, and access to health care. It is a leading source of data for the Congressionally... adult) 44,000 1 15/60 Child Core (adult family member) 17,000 1 10/60 Child/Teen Record Check (medical...

  5. 76 FR 44337 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-07-25

    ... issues, such as cancer, diabetes, and access to health care. It is a leading source of data for the... 1 23/60 Adult Core (sample adult) 44,250 1 14/60 Child Core (adult family member) 17,550 1 9/60 Child Record Check (medical provider) 2,120 1 5/60 Teen Record Check (medical provider) 8,450 1 5/60...

  6. 76 FR 29245 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-05-20

    ... United States. When diabetes strikes during childhood, it is routinely assumed to be type 1, or juvenile-onset, diabetes. Type 1 diabetes (T1D) develops when the body's immune system destroys pancreatic cells... of both type 1 and type 2 diabetes in youth have been among the most concerning aspects of the...

  7. 77 FR 65552 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-10-29

    ... certain workplace and other factors (e.g., co-worker and supervisory support, anti-discrimination policies... outcomes and (3) the organizational (e.g., organizational characteristics, policies and practices) and... (2) their health and safety status and (3) organizational characteristics, policies and practices...

  8. 77 FR 58142 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-09-19

    ...). Background and Brief Description Violence is an important public health problem. In the United States... two years ago may well miss the mark. Local and Federal criminal justice agencies such as the Federal.... Ultimately, this information will guide states in designing programs that reduce multiple forms of violence...

  9. 78 FR 12320 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-02-22

    ... Description The Division of Violence Prevention (DVP), National Center for Injury Prevention and Control... contribute to the understanding of fatal violence associated with schools, guide further research in the area... victim and alleged offender(s)--including demographic data, their academic and criminal records, and...

  10. 76 FR 22902 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-04-25

    ... `black lung'. Demographic and logistical information is gathered from coal mine operators and... and x-ray findings. There are no costs of the NCWAS to respondents other than their time. The total...

  11. 75 FR 65488 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-10-25

    ... these requests, call the CDC Reports Clearance Officer at (404) 639-5960 or send an e-mail to [email protected] CDC at variable frequencies, either weekly or monthly. CDC then calculates and publishes weekly... is no cost to respondents other than their time. The total estimated annualized burden hours are 36...

  12. 78 FR 23766 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-04-22

    ... released into the local air, soil, and surface water. In 1996, residents found out they were exposed... pressure, height, weight, hip, and body girth. A questionnaire will be answered by computer-assisted...

  13. 78 FR 23767 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-04-22

    ... air, soil, and surface water. In 1996, residents found out they were exposed. Concerns grew and led to... informed consent, clinical assessments will be done. These will be for blood pressure, height, weight, hip...

  14. 76 FR 41260 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-07-13

    ...). Background and Brief Description This study directly supports the Healthy People 2020 Healthy Homes' health... green affordable housing's potential to promote healthy homes principles. The title of this study has... particulate matter. To obtain sufficient statistical power, approximately 1000 adults (mothers/primary...

  15. 78 FR 26780 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-05-08

    ... age, race or ethnicity, gender, and family history of individuals who are diagnosed with the disease... registry will collect personal health information that may provide a basis for further scientific studies... will lead to further in-depth studies. The existence of the Web site ( http://wwwn.cdc.gov/als ) is...

  16. 78 FR 4411 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-01-22

    ... Impact of Newborn Screening for Congenital Cytomegalovirus (CMV) Infection--New--National Center for.... Newborn CMV screening offers some clear potential benefits, but few studies have assessed the potential... approval for one year to collect information about newborn CMV screening. The purpose of this information...

  17. 77 FR 50695 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-08-22

    ... health practice, as CDC and OPA will tailor future dissemination activities, and develop needed provider... specializing in obstetrics/ gynecology, family medicine, and adolescent medicine); (b) 2,000 public-sector...

  18. 78 FR 34385 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-06-07

    ... health and social services, nutrition services, healthy and safe school environment, faculty and staff...) State Officials State Recruitment Script 42 1 30/60 (for 2014 study). State Recruitment Script 44 1 30/60 (for 2016 study). District Officials District Recruitment Script 320 1 30/60 (for 2014 study...

  19. 76 FR 24028 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-04-29

    ... 1 30/60 School Environment. State Mental Health and 51 1 30/60 Social Services. State Recruitment... Social Services. District Faculty and Staff 685 1 20/60 Health Promotion. District Recruitment Script.... The components are: Health education, physical education, health services, mental health and social...

  20. 75 FR 58394 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-09-24

    ... obesity, and even childhood leukemia and sudden infant death syndrome (SIDS). However, the groups that are.... National and state reports will use de-identified data to describe incremental changes in practices and...

  1. 77 FR 37677 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-06-22

    ... (202) 395-5806. Written comments should be received within 30 days of this notice. Proposed Project... by chemical name and Chemical Abstract Service (CAS) Registration Number, consistent with accepted... of the Associate Director for Science (OADS), Office of the Director, Centers for Disease Control and...

  2. 76 FR 60497 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-09-29

    ... for any of the three major types of CM (physical abuse, sexual abuse, and neglect) is estimated at... adolescents 0-17 has been estimated at nearly 14%, while physical and sexual abuse are estimated at 3.7% and 0... validated questions to identify 5 types of past child abuse and neglect. Final results will provide an...

  3. 75 FR 57959 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-09-23

    ... Prevention and Health Promotion (NCCDPHP), Centers for Disease Control and Prevention (CDC). Background and... importance of various proposals for policy and environmental change, and whether change has occurred in...

  4. 76 FR 60499 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-09-29

    ... creative concept testing, and online focus groups, primarily for social media concept testing. The... by telephone or online, for campaign evaluation, quantitative social media concept testing, and... purpose, use, methodology, and burden on respondents. A variety of methods will be employed, including: (1...

  5. 76 FR 76413 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-12-07

    ... representatives in state regulatory agencies in the 50 states and the District of Columbia primarily via telephone... exclusively are excluded. Nursing homes and skilled nursing facilities are also excluded, unless they have a...

  6. 77 FR 33745 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-06-07

    ... Medicaid Services (CMS) data on nursing home, home health, and hospice care); (3) update data more... will be collected in the 50 states and the District of Columbia from two types of LTC facilities: 11...

  7. 78 FR 25741 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-05-02

    ..., poor concentration and memory, constantly being on-guard, disturbed sleep, high irritability); and... Veteran's attitudes and perceptions about physical, psychological, physiological, and functional barriers...

  8. 78 FR 44566 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-07-24

    ... Work@Health Program: Phase 1 Needs Assessment and Pilot Training Evaluation--New--National Center for... Work@Health Program, a comprehensive workplace health promotion training program, to support employers... lifestyle choices. The Work@Health curriculum will be based on a problem-solving approach to improving...

  9. 75 FR 48349 - Agency Forms Undergoing Paperwork Reduction Act review

    Science.gov (United States)

    2010-08-10

    ... monitor syndrome-based (e.g., case information collected in emergency departments (EDs) and diagnostic... syndromic surveillance systems. EARS has been designed and used to monitor syndromic data from emergency... events such as the Beijing Summer Olympics; multiple Superbowls (football) and World Series (baseball...

  10. 78 FR 22551 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-04-16

    ... messaging and smartphone Web access are immediate, accessible, and anonymous, a combination of features that... feasibility study to evaluate the process of conducting Web surveys by smartphone [[Page 22552

  11. 77 FR 35404 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-06-13

    ... public health. Text messaging and smartphone web access are immediate, accessible, and anonymous, a combination of features that could make smartphones ideal for the ongoing research, surveillance, and... message and smartphone, the outcomes of the surveys, and the value of the surveys. The universe for this...

  12. 78 FR 22552 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-04-16

    ... Form with a Participant Biosafety Compliance Letter of Agreement; (c) revision of the Pre-shipment... the development of practice standards. Participants in this program include domestic clinical and... response (in respondent hours) Domestic Laboratory Participant Biosafety 93 2 5/60 Compliance Letter of...

  13. 77 FR 66468 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-11-05

    ... intentions, practices, behaviors, skills, self-efficacy, and health information needs and sources. The... hard-to-reach populations in order to improve routine and emergency public health programs and...

  14. 77 FR 2730 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-01-19

    ... numerous, and they occur at many levels. In 2009, CDC issued guidance outlining 24 community-based strategies to encourage healthy eating and active living. Some of these strategies are being implemented by... costs to respondents other than their time. The total estimated annualized burden hours are 291...

  15. 75 FR 38104 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-07-01

    ... relationships. Communication research indicates that campaign planning implementation must employ a consumer...) knowledge and attitudes regarding healthy and unhealthy relationships, and obtain their feedback regarding... diverse groups of young people to complete: (1) Ten-minute online surveys, with 200 respondents, up to...

  16. 78 FR 65655 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-11-01

    ... which will include (1) an introduction to the project, (2) a pre-test concerning miners' attitude... computer that has the appropriate software. It is estimated it will take no more than 5 minutes for the..., Office of Scientific Integrity, Office of the Associate Director for Science, Office of the Director...

  17. 76 FR 51984 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-08-19

    ... promotional strategies, the populations affected by these strategies, and their effect on QL and Web-based... advertising; impact in relation to QL call volume; and client characteristics. Up to 50 state-based TCPs will...

  18. 76 FR 21747 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-04-18

    ... Project Development and Evaluation of Eagle Books and Youth Eagle Books for American Indians and Alaska...), Centers for Disease Control and Prevention (CDC). Background and Brief Description The development of... physical activity, and social support. A number of health communication products have been developed...

  19. 76 FR 12964 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-03-09

    ..., and the effect on the physical environment in which they live. An ongoing public health concern... from other surveys designed to measure anxiety, depression, and potential stress-associated physical... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention [30Day-11-11BH...

  20. 76 FR 16629 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-03-24

    ... Project Formative Research to Develop Social Marketing Campaigns--Routine HIV Testing for Emergency... formative research study to support CDC's efforts in further developing three social marketing campaigns targeting infectious disease specialists, primary care physicians, and emergency department physicians. The...

  1. 75 FR 64732 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-10-20

    ... customer satisfaction surveys. These surveys provide the public with ongoing opportunity to express their... the public. Customers are defined as any individual or group seeking health or public health... customer satisfaction surveys. The Interactive Voice Response Survey--offered in English and Spanish and...

  2. 75 FR 53311 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-08-31

    ...; customer satisfaction surveying; ethnography/observational studies; and mystery shopping. The data will be... improvements in people's health. To do this, the agency is defining specific health protection goals to... development, implementation and satisfaction regarding public health services, products, communication...

  3. 75 FR 65487 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-10-25

    ...; customer satisfaction surveying; ethnography/observational studies; and mystery shopping. The data will be... improvements in people's health. To do this, the agency is defining specific health protection goals to... development, implementation and satisfaction regarding public health services, products, communication...

  4. 75 FR 16128 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-03-31

    ..., the Division of Nutrition, Physical Activity, and Obesity (DNPAO) at the Centers for Disease Control... physical activity levels among children in low-income communities. The New York City Health Bucks program... participants; identify factors serving as barriers and facilitators to program implementation and expected...

  5. 75 FR 44795 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-07-29

    ... reconvened workgroups with these same organizations to revise the data collection instruments, in order to.... Proposed Project National Public Health Performance Standards Program Local Public Health Governance... State, Tribal, Local and Territorial Support is proposing to extend the formal, voluntary data...

  6. 75 FR 44798 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-07-29

    ... of public health. In 2005, CDC reconvened workgroups with these same organizations to revise the data.... Proposed Project National Public Health Performance Standards Program Local Public Health Governance..., voluntary data collection that assesses the capacity of local boards of health to deliver the essential...

  7. 75 FR 69086 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-11-10

    ... Substances and Disease Registry (ATSDR). Background and Brief Description On October 10, 2008, President Bush... factors (such as age, race or ethnicity, gender, and family history of individuals diagnosed with the... than their time. The estimated annualized burden hours are 703. Estimated Annualized Burden Hours...

  8. 78 FR 33096 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-06-03

    ... Disease Control and Prevention (CDC). Background and Brief Description This project involves a... the participant prior to the testing session. We also included the time needed to review the informed... is to study the natural history of lung disease. For this study, we plan on interviewing and...

  9. 76 FR 78924 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-12-20

    ... Control and Prevention (CDC). Background and Brief Description The scope of the HIV epidemic in the United... collected in these MSAs at two time points between 2012 and 2014. Two surveys will be used in this project..., alcohol and drug use history, HIV testing experiences, exposure to HIV prevention messages, and...

  10. 77 FR 73470 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-12-10

    ...). Background and Brief Description Congenital syphilis (CS) is an important sentinel health event that marks...: ``Mothers obstetric history'', ``Did mother have treponemal test result: If so, when was the test performed... respondents other than their time. The total estimated annual burden hours are 62. Estimate of Annualized...

  11. 76 FR 17869 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-03-31

    ... Brief Description CDC began formally partnering with CBOs in the late 1980s to expand the reach of HIV... of their history and credibility with target populations and their access to groups that may not be easily reached. Over time, CDC's program for HIV prevention by CBOs has grown in size, scope, and...

  12. 78 FR 70563 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-11-26

    ... physical activity, and policies and practices that support access to healthy food and healthy eating. Data... solutions for healthy behaviors or choices. Finally, information collected through this survey may serve as... for one year. Participation is voluntary and there are no costs to respondents other than their time...

  13. 77 FR 13607 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-03-07

    ... their associated monetary impacts under various scenarios. CDC and NIH have previously collaborated on..., community-based programs that employ multiple policy and environmental change strategies. Information to be...

  14. 76 FR 64351 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-10-18

    ... hospital administrators, security directors and/or risk managers, many of whom participated in the... events, violence prevention committee, written violence prevention plan, violence risk assessments, post... enactment of the regulations. Third, we will conduct a nurse survey. The survey will describe the workplace...

  15. 77 FR 65894 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-10-31

    ... drinking water distribution systems. A study conducted in Norway from 2003-2004 found that people exposed... or adult household member employed at daycare, pets in the household and other animal contact, and...

  16. 75 FR 9902 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-03-04

    ...), Cyclospora, Dengue, Hantavirus, Kawasaki Syndrome, Legionellosis, Lyme disease, Malaria, Plague, Q Fever... for possible causes or sources of the diseases, and develop guidelines for prevention and treatment............ 55 200 25/60 CJD 20 2 20/60 Cyclosporiasis 55 10 15/60 Dengue 55 182 15/60 Hantavirus 40 3 20/60...

  17. 78 FR 15368 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-03-11

    ... include: Creutzfeldt-Jakob Disease (CJD), Cyclosporiasis, Dengue, Hantavirus, Kawasaki Syndrome... treatment. The data collected will also be used to recommend target areas most in need of vaccinations for... Epidemiologist Dengue 55 182 15/60 Epidemiologist Hantavirus 46 3 20/60 Epidemiologist Kawasaki Syndrome...

  18. 77 FR 27064 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-05-08

    ... identified in a traditional survey interview, such as interpretive errors and recall accuracy, are uncovered... contract) research, demonstrations, and evaluations respecting new or improved methods for obtaining... CDC surveys (such as the NCHS National Health Interview Survey, OMB No. 0920-0214) and other federally...

  19. 75 FR 6670 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-02-10

    ... (CDC) publishes a list of information collection requests under review by the Office of Management and... application of Federal regulations. The regulations in 42 Part 70 were developed to facilitate Federal action... permit issued by State health authority. 42 CFR 70.4 Report by the master of a Master of a vessel or 1...

  20. 78 FR 4149 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-01-18

    ... (CDC) publishes a list of information collection requests under review by the Office of Management and... forms based on the type of respondent: an ill traveler, or the master of a vessel or conveyance engaged... application of Federal regulations. The regulations in 42 Part 70 were developed to facilitate Federal action...

  1. 78 FR 20920 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-04-08

    ... such as medicines taken, food eaten, hobbies, jobs, etc. In addition, ATSDR asks questions on... manner. The benefits to using the EI Generic Clearance include submission of a standardized OMB review...., breathing, eating, touching), and number of other sources of the chemical(s) (e.g., products used, jobs...

  2. 78 FR 59700 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-09-27

    ... phases of the survey). Infection prevention personnel in participating hospitals and EIP site personnel...-Associated Infections (HAIs) and Antimicrobial Use in U.S. Acute Care Hospitals--Reinstatement--(0920- 0852... Control and Prevention (CDC). Background and Brief Description Preventing healthcare-associated infections...

  3. 78 FR 13344 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-02-27

    ... phases of the survey). Infection prevention personnel in participating hospitals and EIP site personnel... respondent in hours Infection Prevention Personnel in Participating Hospitals.... 500 75 15/60 [[Page 13345...-Associated Infections (HAIs) in Acute Care Hospitals in the United States--Extension--(0920-0852 exp.5/ 31/13...

  4. 75 FR 10803 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-03-09

    ... were collected from a sample of 338 hospitals; 5% of hospitalized patients acquired an infection not... local and national policy makers and hospital infection control personnel regarding appropriate targets... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention [30Day-10-09AM...

  5. 76 FR 32212 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-06-03

    ... (CDC) publishes a list of information collection requests under review by the Office of Management and....gov . Send written comments to CDC Desk Officer, Office of Management and Budget, Washington, DC or by... to fill funding gaps in programs that deal with the leading causes of death and disability. Block...

  6. 78 FR 44568 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-07-24

    ... developmental milestones among parents of 3-year-old children and actively engage them in the monitoring of their child's development. CDC partnered with Lysol and Reach Out and Read (ROR), a non-profit... clinics each received 300 copies of Amazing Me for distribution to parents of 3-year-old children during...

  7. 77 FR 76492 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-12-28

    ... up. To compound the problem, many pediatric audiologists may be proficient evaluating children age 5... Agencies (DSHPSHWA), Healthcare Resources and Services Administration (HRSA), University of Maine Center..., on-demand access by the audiologists. Financial cost is minimized because no mailing fee will be...

  8. 78 FR 6327 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-01-30

    ... of illness and disability of the population of the United States. This three-year clearance request... submitting inpatient level data in the form of electronic Uniform Bill (UB-04) administrative claims data as... include universities, research organizations, many in the private sector, foundations, and a variety of...

  9. 76 FR 76415 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-12-07

    ... Health and Human Services (HHS) to make and enforce regulations necessary to prevent the introduction... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention [30 Day-12-11JQ... Project Data Collection for Evaluation of Education, Communication, and Training Activities--New--National...

  10. 75 FR 12753 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-03-17

    ... United States and the volume of laboratory tests available certainly warrant such a model. The Laboratory... or studies demonstrating practice effectiveness in the peer reviewed literature, but that they... literature. Healthcare organizations and facilities (laboratories, hospitals, clinics) will have the...

  11. 77 FR 69484 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-11-19

    ... surrounding and preceding the onset of a problem. The data must be collected in a timely fashion so that... causative agent(s), transmission patterns, and severity of the outbreak. These data, together with trend...

  12. 77 FR 52334 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-08-29

    .... Efforts are focused in communities with high rates of teen pregnancy in under- served African American and... strategies to reduce teen pregnancy; and (4) supporting the sustainability of the community-wide teen... organizations, which have been funded to support community-wide teen pregnancy prevention (TPP) activities. The...

  13. 78 FR 27390 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-05-10

    ... programs voluntarily self-nominate their practice or healthcare system by completing a web-based nomination... CDC with a ranked list of nominees. Finalists will be asked to participate in a data verification process that includes verification of how information was obtained from electronic records, remote...

  14. 75 FR 65355 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-10-22

    ... involving media, access, price, point of purchase decision, and support services (MAPPS). These approaches... modify the environmental determinants of risk factors for chronic diseases, prevent or delay chronic... collect information from a subset of CPPW States and communities to gain insight into the factors that...

  15. 76 FR 65512 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-10-21

    ... (CDC) publishes a list of information collection requests under review by the Office of Management and....gov . Send written comments to CDC Desk Officer, Office of Management and Budget, Washington, DC 20503... parents; brand ambassadors; educators; school leadership; program implementers; community representatives...

  16. 77 FR 11539 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-02-27

    ... (CDC) publishes a list of information collection requests under review by the Office of Management and... . Send written comments to CDC Desk Officer, Office of Management and Budget, Washington, DC 20503 or by... where participants include: Middle school students age 11 to 14 years; middle school parents; brand...

  17. 75 FR 80055 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-12-21

    .... Information is collected electronically through a web-based Cost Assessment Tool (CAT) and includes: Staff and... Minimum Data Elements (MDE) for the NBCCEDP (OMB 0920-0571, exp. 11/30/2012). Cost information to be collected through the CAT will complement information currently collected through the MDE project. There are...

  18. 77 FR 38065 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-06-26

    ... information about congenital CMV to the target audiences and adopting CMV preventive guidelines. We will also...- and post- interventions with a larger target audience sample (N=800). We estimate that we will screen...

  19. 76 FR 60498 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-09-29

    ... influential as possible, target audience members or representatives must be involved in developing the messages and provisional versions of the messages must be tested with members of the target audience..., salience, appeal, and persuasiveness to target audiences. Guide the action of health communication...

  20. 77 FR 61410 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-10-09

    ... collected to assess whether the YSI program can be implemented with fidelity; reach its target audience of... obtained through Google Analytics to assess how visitors (particularly the target audience) navigate and... use with other audiences. Primary information collection will consist of two Web-based surveys of YSI...

  1. 75 FR 52953 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-08-30

    ... responsible for establishing and managing the national reporting system of epidemiologic data for notifiable... jurisdiction's response to the questionnaire will be used by the NEDSS implementation and management teams to..., the maximum annual frequency of responses per jurisdiction is three. The NEDSS team will request the...

  2. 77 FR 5519 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-02-03

    ... respondents for completing the survey questionnaire; conducting a limited process evaluation that identifies... burden. The third objective is to identify and critically evaluate different methods of study recruitment... one of two groups: a low-intensity recruitment group or a moderate- intensity recruitment group. All...

  3. 77 FR 17063 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-03-23

    ... transmission: Sexual and drug use behaviors; patients' access to, use of and barriers to receiving HIV- related... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention [30Day-12-0740.../Adolescent Spectrum of HIV Disease (ASD). Both projects stopped data collection in 2004. Although CDC...

  4. 76 FR 62412 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-10-07

    ... for Registration, (2) Request to Transfer Select Agent or Toxin, (3) Report of Theft, Loss, or Release..., or Release of Select Agent and Toxin, (4) Report of Identification of Select Agent or Toxin. There... Release of Select Agent or Toxin; (4) Report of Identification of Select Agent or Toxin; and (5) Request...

  5. 77 FR 27775 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-05-11

    ...-framed (SMART). CTG awardees are required to provide semi-annual reports to CDC that describe and update... the CTG initiative from the Department of Health and Human Services (HHS), the White House, Congress...

  6. 76 FR 63925 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-10-14

    ... efficacy in reducing HIV transmission among MSM of color. Given the conspicuous absence of (1) evidence... participants with the information, motivation, and skills necessary to reduce their risk of transmitting or...

  7. 76 FR 34705 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-06-14

    ... Project Focus Group Study for Raising Public Awareness of Deep Vein Thrombosis/Pulmonary Embolism--New..., thigh, or pelvis, but they can also occur in the arm. In more than one third of people affected by DVT... risk by understanding DVT/PE and its risk factors. DVT/PE affects people of all races and ages. [[Page...

  8. 78 FR 65652 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-11-01

    ... 12 and older), grip strength (ages 6 and older), anthropometry (all ages), 24-hour dietary recall... absorptiometry (total body composition ages 6-59 and osteoporosis, vertebral fractures and aortic calcification... provided for mailing it back; a second 24-hour dietary recall (all ages) is scheduled to be conducted by...

  9. 76 FR 15315 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-03-21

    ... material. Health care providers manage both routine surge (predictable fluctuations in demand associated... and Primary Care 43 1 1 Public Health and Preparedness/Coalition Leader 20 1 1 Petunia Gissendaner...

  10. 75 FR 46942 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-08-04

    ... 1985 by NIOSH; and, in 2000 the Institute of Medicine conducted a workforce assessment at NIOSH's... desired professional competencies (i.e., knowledge, skills, and abilities) required for the coming decade...

  11. 77 FR 17064 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-03-23

    .... The NSFG program produces descriptive statistics which measure factors associated with birth and pregnancy rates, including contraception, infertility, marriage, divorce, and sexual activity, in the US population 15-44; and behaviors that affect the risk of sexually transmitted diseases (STD), including HIV...

  12. 75 FR 80505 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-12-22

    ... environment and interview the store managers in person. Data will be collected on compliance with the safety.... Proposed Project The Evaluation of Ordinances to Prevent Workplace Violence in Convenience Stores--NEW--National Institute for Occupational Safety and Health (NIOSH), Centers for Disease Control and Prevention...

  13. 78 FR 45201 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-07-26

    ... general population survey includes questions related to knowledge of and attitudes toward colorectal... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention [30Day-13-12QU... Disease Prevention and Health Promotion (NCCDPHP), Centers for Disease Control and Prevention (CDC...

  14. 78 FR 42079 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-07-15

    ... violence prevention services, social desirability, and attitudes toward dating violence. These measures... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention [30Day-13-0861... make it a public health concern that requires early and effective prevention. To date, only three...

  15. 75 FR 33622 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-06-14

    ... the health and safety of workers. In this capacity, NIOSH will conduct a national survey of long-haul... injuries. In evaluating the potential health effects of the 2005 hours-of-service ruling, the Federal Motor... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention [30-Day-10-09AX...

  16. 75 FR 16485 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-04-01

    ... notice. Proposed Project Survey of Healthcare Workers' Health and Safety Practices--New-- National... responsibility to conduct research to advance the health and safety of workers. In this capacity, NIOSH will... risk for many of the types of adverse health effects potentially caused by exposure to hazardous...

  17. 78 FR 15366 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-03-11

    ... research to advance the health and safety of workers. In this capacity, NIOSH will conduct an exposure... of the size of the workforce exposed to nanomaterials. Health effects from exposure to nanomaterials... manufacturing settings. Thus, an epidemiologic study to determine whether early or late health effects occur...

  18. 75 FR 22138 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-04-27

    ... the health and safety of workers. In this capacity, NIOSH will conduct a national survey of long-haul... injuries. In evaluating the potential health effects of the 2005 hours-of-service ruling, the Federal Motor... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention [30 Day-10-09AX...

  19. 76 FR 44590 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-07-26

    ... verbally to participants in English. Once this study is complete, results will be made available via... study, it is expected that improved use of OSH programs will lower rates of injuries and fatalities for...) is to promote safety and health at work for all people through research and prevention. In this...

  20. 77 FR 28597 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-05-15

    ... order to increase the wealth of data on health care utilization in hospitals across episodes of care and... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention [30Day-12-12AL... Hospital Care Survey--New-- National Center for Health Statistics (NCHS), Centers for Disease Control and...

  1. 75 FR 6671 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-02-10

    ... Project Congenital Syphilis (CS) Case Investigation and Report Form (CDC73.126), OMB No. 0920-0128, (exp. 02/28/2010)--revision--National Center for HIV/AIDS, Viral Hepatitis, STD and TB Prevention (NCHHSTP... proposed revision is to continue data collection for congenital syphilis case investigations with a revised...

  2. 76 FR 63924 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-10-14

    ...), National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP), Centers for Disease... review and/or onsite investigations by TB control staff. The purpose of this information collection...

  3. 75 FR 8725 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-02-25

    .... Proposed Project CDC Web site and Communication Channels Usability Evaluation, (OMB no. 0925-0735, exp. 3/31/2010)--Revision--National Center for Health Marketing (NCHM), Centers for Disease Control and..., mobile-based or other electronic communication channels hosting CDC content on an ongoing basis. It is...

  4. 76 FR 78262 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-12-16

    ... Project Web-Based HIV Behavioral Survey among Men who have Sex with Men-- New--National Center for HIV... of the proposed web-based behavioral survey of internet-using MSM are to (a) describe the prevalence... areas (MSAs) with high AIDS prevalence. Internet-using MSM will be recruited through a direct marketing...

  5. 77 FR 34951 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-06-12

    ... activities such as establishing a worksite committee, having senior leadership support, and forming community partnerships and health coalitions, and (3) to promote peer-to-peer business mentoring that encourages...

  6. 78 FR 72087 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-12-02

    ... and their infants. The collection of saliva cells by the mother, father and infant takes about 15... or birth hospital records; mothers of case and control infants will be interviewed using a computer... cheek and gum; parents will be asked to swab a total of five sponges per infant. The infant's mother and...

  7. 77 FR 24960 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-04-26

    ... themselves and their infants for DNA testing. The collection of cheek cells by the mother, father, and infant... questionnaire. 3,600 1 1 Mothers, fathers, infants Cheek Cell Specimen 10,800 1 10/60 Collection. [[Page 24961... from birth certificates or birth hospital records. Mothers of case and control infants are interviewed...

  8. 77 FR 51806 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-08-27

    ... support evidence-based prevention and wellness strategies. The cornerstone of the initiative is the... National Prevention Media Initiative. Although originally planned as a national campaign, CDC determined... campaigns. OMB approval is requested for one year. The estimated burden per response is one minute or less...

  9. 77 FR 24207 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-04-23

    ... dogs upon arrival to the United States are also requested. The CDC form 75.37, ``Notice of Importers of Dogs'' will now be identified as CDC form 75.37 ``NOTICE TO OWNERS AND IMPORTERS OF DOGS: Requirement for Dog Confinement.'' The form has been changed to enhance clarity around the purpose of the form...

  10. 76 FR 4910 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-01-27

    ..., Viral Hepatitis, STD, and TB Prevention (NCHHSTP), Centers for Disease Control and Prevention (CDC... Health Service for the prevention and control of HIV infection, viral hepatitis, sexually transmitted... information on HIV/ AIDS, viral hepatitis, STDs, and TB, supporting NCHHSTP's mission to link Americans to...

  11. 78 FR 68848 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-11-15

    ... HIV/AIDS, Viral Hepatitis, STD, & TB Prevention (NCHHSTP), Centers for Disease Control and Prevention (CDC). Background and Brief Description The National Center for HIV/AIDS, Viral Hepatitis, STD, and TB.... Public Health Service for the prevention and control of HIV infection, viral hepatitis, sexually...

  12. 77 FR 71794 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-12-04

    ... Development--(OMB 0920-0840, Exp. 1/31/2013)--Revision--National Center for HIV/AIDS, Viral Hepatitis, STD, TB... transmitted diseases/infections (STD/STI), viral hepatitis, and tuberculosis elimination. Formative research... identities, and health care that underlie the epidemiology of HIV/AIDS, viral hepatitis, STDs, and TB in the...

  13. 77 FR 40887 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-07-11

    ... Network (SSuN)-(OMB 0920-0842 Exp: 1/31/2013)-- Revision--National Center for HIV/AIDS, Viral Hepatitis... to established and emerging trends in STDs, HIV, and viral hepatitis; and (3) to identify and... in STDs, HIV, and viral hepatitis. SSuN will help identify and evaluate the effectiveness of public...

  14. 75 FR 67365 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-11-02

    ...)-- Reinstatement with Change--National Center for HIV/AIDS, Viral Hepatitis, STD, & TB Prevention (NCHHSTP... HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP) proposes to continue data collection for... prevention and control of HIV infection, viral hepatitis, sexually transmitted diseases (STDs), and...

  15. 76 FR 74066 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-11-30

    ... leading cause of death for the first four decades of life, regardless of gender, race, or socioeconomic... child maltreatment, a NCIPC priority, CDC is collaborating with the Health Resources and Services...

  16. 76 FR 12121 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-03-04

    ... Project National HIV Behavioral Surveillance System (NHBS) 0920-0770 (exp. 03/31/2011)--Revision-National...-based organizations, community planning groups and other stakeholders. This project addresses the goals... health care access and utilization, use of pre-exposure prophylaxis, homophobia, HIV stigma, and...

  17. 76 FR 12359 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-03-07

    ... Project National HIV Behavioral Surveillance System (NHBS)--0920-0770 exp. 03/31/2011)--Revision-National...-based organizations, community planning groups and other stakeholders. This project addresses the goals... health care access and utilization, use of pre-exposure prophylaxis, homophobia, HIV stigma, and...

  18. 78 FR 57640 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-09-19

    ...: Examples that compliment qualitative research on evidence based interventions. 4. Demonstrating return on... and track; therefore, OPHPR must use a creative method to collect relevant stories on the impacts of... Annualized Burden Hours Number of Average burden Type of respondents Form name Number of responses per per...

  19. 78 FR 75568 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-12-12

    ... obtain data using two qualitative data collection methods. The first method includes focus groups to... audiences for this research: First responders, including police, fire fighters and emergency medical service... telephone. Although the Recruitment Screeners vary by respondent type, the same Moderator's Guide will be...

  20. 78 FR 52771 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-08-26

    ... community preparedness and recovery with attention to types of services that most effectively promote the natural resilience of survivors. Two primary research questions will guide the proposed study: 1. How did... recovery. Specifically, the study design includes two main components (qualitative and quantitative...

  1. 78 FR 21160 - Paperwork Reduction Act; 30-Day Notice

    Science.gov (United States)

    2013-04-09

    ... the continuity and improvement of the Media Campaign. Type of Collections: OMB 3201-0011-Qualitative...--Qualitative Research--Quarterly; OMB 3201-0006--Copy testing--Quarterly; OMB 3201-0010--Tracking Study...--Qualitative Research--$19,800; OMB 3201-0006--Copy testing--$16,500; OMB 3201-0010--Tracking Study-- $37,700...

  2. 77 FR 64808 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-10-23

    ... related to health such as arthritis, asthma, osteoporosis, infectious diseases, diabetes, high blood pressure, high cholesterol, obesity, smoking, drug and alcohol use, physical activity, environmental...

  3. 77 FR 58843 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-09-24

    .... All of these effects have lifelong implications. Health care professionals play a crucial role in... surveys of multiple provider types that although they might be familiar with the teratology and clinical...

  4. 76 FR 53135 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-08-25

    ...)--National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP), Centers for Disease...-female transgender persons to assess prevalence of and trends in: (1) Risk behaviors for HIV infection... proportion of people who consistently engage in behaviors that reduce risk of HIV transmission or acquisition...

  5. 78 FR 9698 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-02-11

    ... standard in healthcare, this has been limited in laboratory medicine. No single-evidence-based model for... United States and the volume of laboratory tests available certainly warrant such a model. The Laboratory... Integrity (OSI), Office of the Associate Director for Science (OADS), Office of the Director, Centers for...

  6. 78 FR 17409 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-03-21

    ... the social ecological model (SEM) that coordinate and align with existing prevention strategies at the... reporting. Dated: March 15, 2013. Ron A. Otten, Director, Office of Scientific Integrity (OSI), Office of...

  7. 78 FR 11886 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-02-20

    ... the evaluation, a standard model of TDV prevention (Safe Dates administered in 8th grade) will be compared to a comprehensive model (programs administered in 6th, 7th, and 8th grade as well as parent.... Dated: February 12, 2013. Ron A. Otten, Director, Office of Scientific Integrity (OSI), Office of the...

  8. 77 FR 2729 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-01-19

    ...) characterize individual and employment characteristics that are associated with non-reporting of workplace... workplace injuries. This presumed undercount potentially decreases health and safety funding because of a... National Academy of [[Page 2730

  9. 75 FR 80506 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-12-22

    ..., because it directly impacts the infection control and personal protective measures that should be taken by... participants will be screened using a short health questionnaire to verify that they have influenza-like... a previous study using similar forms, we estimate that the health questionnaire will require about 5...

  10. 76 FR 68464 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-11-04

    ... asthma supplement will collect information on the clinical decisions providers make when confronted with... patient care. In 2006, physicians and mid-level providers (i.e., nurse practitioners, physician assistants, and nurse midwives) practicing in community health centers (CHCs) were added to the NAMCS sample, and...

  11. 75 FR 8724 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-02-25

    ... Project A Controlled Evaluation of Expect Respect Support Groups (ERSG): Preventing and Interrupting Teen... (CDC). Background and Brief Description The prevalence and consequences of teen dating violence make it... prevented sexual violence. In order to protect young people and build the evidence for effective prevention...

  12. 76 FR 78925 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-12-20

    ... wishes to conduct a study to identify barriers to, and facilitators of, asthma education among health... Project Asthma Education Study: Making Health Care Providers Better Asthma Educators--New-National Center... action at appropriate times. From this, it follows that the education provided by health care providers...

  13. 78 FR 40742 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-07-08

    ... family. The purpose of the DELTA FOCUS (Domestic Violence Prevention Enhancement and Leadership Through... CDC efforts to support them; process, program and strategy implementation factors that affect their... the public health approach; and sustainability of prevention activities and successes. The DF Survey...

  14. 76 FR 13191 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-03-10

    .... Proposed Project FoodNet Non-O157 Shiga toxin-Producing E. coli Study: Assessment of Risk Factors for... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention [30-Day-11-11BI... cases, life-threatening hemolytic uremic syndrome (HUS). HUS occurs most frequently following infection...

  15. 75 FR 57960 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-09-23

    ... violence in one rural North Carolina school district, but appropriateness of the program with urban, high-risk adolescents is unknown. CDC has learned additional information about violence and risk factors for...). Background and Brief Description Safe Dates, a dating violence prevention curriculum for 8th and 9th grade...

  16. 76 FR 28233 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-05-16

    ... Student and School-wide Experiences of Violence and Fear--New--National Center for Injury Prevention and... and violence, and related variables. If the CSA tool is shown to measure characteristics of the school environment that are associated with fear and violence-related behaviors in school, then it may be used as the...

  17. 77 FR 45616 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-08-01

    ... has grown in size, scope, and complexity, responding to changes in approaches to addressing the epidemic, including the introduction of new guidances; effective behavioral, biomedical, and structural... Prevention (DHAP) provides national leadership and support for capacity building assistance (CBA) to help...

  18. 75 FR 24704 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-05-05

    ... babies, children, and adults with disabilities. As part of these efforts the Center is actively involved... changes include adding a question about how many infants with hearing loss are receiving only monitoring...

  19. 76 FR 58517 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-09-21

    ... then be used to determine effective food safety prevention methods. The purpose of this food safety... to conduct a recruiting screener with approximately 2,057 worker respondents to obtain the needed... 3 minutes. As we plan to conduct up to 3 data collections annually, the maximum annual recruiting...

  20. 75 FR 3737 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-01-22

    ... days of this notice. Proposed Project Questionnaire Design Research Laboratory (QDRL) 2010-2012, (OMB... of health services in the United States. The Questionnaire Design Research Laboratory (QDRL) conducts... is the cognitive interview. In a cognitive interview, a questionnaire design specialist interviews a...

  1. 77 FR 27065 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-05-08

    ... Prevention and Health Promotion (NCCDPHP), Centers for Disease Control and Prevention (CDC) and the Center..., cigarette smoking costs more than $193 billion; $97 billion in lost productivity plus $96 billion in health...

  2. 75 FR 52952 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-08-30

    ... Prevention and Health Promotion (NCCDPHP), Centers for Disease Control and Prevention (CDC). Background and... survey asks registry managers to identify training needs that would improve registry productivity, and to...

  3. 75 FR 28620 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-05-21

    ... Promotion (NCCDPHP), Centers for Disease Control and Prevention (CDC). Background and Brief Description... approximately 440,000 deaths annually and contributing to $92 billion annually in lost worker productivity...

  4. 77 FR 40359 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-07-09

    ... Chronic Disease Prevention and Health Promotion (NCCDPHP), Centers for Disease Control and Prevention (CDC... annually in lost worker productivity. Although the prevalence of current smoking among adults decreased...

  5. 76 FR 27326 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-05-11

    .... The survey covers basic physician demographic characteristics (year of birth, gender, years in... tools, and computerized order entry systems. To date, no systematic study has been conducted to...

  6. 78 FR 71615 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-11-29

    ... 2 Training and Technical Assistance Evaluation--New--National Center for Chronic Disease Prevention..., implementation, and evaluation of effective worksite health strategies and interventions; and (3) Increase the...) A ``Hands-on'' instructor- led workshop model (T1), (2) a self-paced ``Online'' model (T2), (3) a...

  7. 78 FR 9695 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-02-11

    ... interventions. This information is needed to complete a research study of the costs and costs savings to society...: 1. Effects on fatalities and injury prevention: We have specifically determined fatality and injury... facility costs. This Information Collection Request (ICR) is being requested to fill these gaps in...

  8. 75 FR 67374 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-11-02

    ... workers on their job satisfaction and clients on their satisfaction with caregiver services, on the... demographic variables including age, sex, race, education, income, primary language, and marital status...

  9. 76 FR 41797 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-07-15

    .... Proposed Project Community Assessment and Engagement Process--New--Division of Health Assessment and... implement ATSDR's programs, the agency works with communities by listening to and understanding their health concerns and seeking their guidance on where, when, and how to take public health actions. Communities in...

  10. 76 FR 61363 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-10-04

    ... Project Central America Water and Sanitation Program Sustainability Evaluation and Qualitative Interview... into a study of the long-term sustainability of WASH interventions. This research will focus on... how to best maximize their investments to ensure long-term community health. This research includes...

  11. 78 FR 75920 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-12-13

    ... using computer assisted personal interviews (CAPI). A core set of data is collected each year that... should be received within 30 days of this notice. Proposed Project The National Health Interview Survey... National Health Interview Survey is a major source of general statistics on the health of the U.S...

  12. 78 FR 67148 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-11-08

    ... and treatment for emergency responders; recovery and cleanup workers; and residents, building... the Program must complete an enrollment form. The following information includes the definition of... (whether fire or emergency personnel, active or retired), worked for a recovery or cleanup contractor, or...

  13. 78 FR 20110 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-04-03

    ... Project Science to Practice: Developing and Testing a Marketing Strategy for Preventing Alcohol-related... marketing strategy for The Safer Campuses and Communities intervention, a comprehensive, community-based... the spring and fall semester of the 2012-2013 academic years, and will constitute a marketing strategy...

  14. 32 CFR 22.525 - Paperwork Reduction Act.

    Science.gov (United States)

    2010-07-01

    ... the Office of Management and Budget before collecting information using forms, schedules... other than agencies, instrumentalities, or employees of the United States. (2) Questions from agencies, instrumentalities, or employees of the United States which are to be used for statistical compilations of general...

  15. 75 FR 9223 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-03-01

    ... school dismissals due to rapidly increasing absenteeism among students or staff that impacted at least.... Optional data elements include: name of person submitting information; the organization/agency; phone number of the organization/agency; and e-mail address. There is no cost to respondents other than their...

  16. 78 FR 18598 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-03-27

    ... increasing absenteeism among students or staff. These dismissals impacted at least 824,966 students and 53... and organizations and not as private citizens. The data collection does not involve personally...

  17. 75 FR 14163 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-03-24

    ... resulted in at least 1351 school dismissals due to rapidly increasing absenteeism among students or staff... information; the organization/agency; phone number of the organization/agency; and e-mail address. There is no...

  18. 76 FR 76733 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-12-08

    ... point-of-sale. The EDI transmission occurs in real-time as the prescription transaction is made. The... appeal the decision. Once someone is enrolled, he or she may request approval for reimbursement of travel if the individual must travel more than 250 miles to receive healthcare services. Healthcare...

  19. 77 FR 47073 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-08-07

    ... accelerometry data. An adult YABS respondent who is the parent or guardian of a child in the household will be... secondhand smoke and to improve nutrition and physical activity among children and adults (and are part of... circumference, secondhand smoke exposure, and blood pressure. Each adult respondent in the YABS will be asked to...

  20. 78 FR 21126 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-04-09

    ... Employees International Union (SEIU) Local 1199. Only health care workers whose job titles are in one of...) techs, registered nurses (RNs), respiratory therapists, and dental assistants. Furthermore, recruitment... SEIU1199 members will be done either online or over the telephone. After the initial recruitment period...

  1. 77 FR 61407 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-10-09

    ... agreements and advertising, however, smoking restrictions in MUH have largely been limited to common areas... study will demonstrate how SHS exposure can be measured and will quantify how exposure changes when... implementation of smoke-free policies in MUH and the cost-effectiveness of these policies. CDC is authorized to...

  2. 76 FR 45257 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-07-28

    ... Behavioral Intervention for Tics (CBIT) treatment. In addition, a range of professional health education.... Proposed Project Tourette Syndrome National Education and Outreach Program--New-- National Center on Birth... movement disorder characterized by involuntary motor and vocal tics that typically manifest during...

  3. 77 FR 61406 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-10-09

    ... series of working groups comprised of local, state, and federal public health partners. Burden hours are... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention [30Day-12-12PK... days to weeks and may cause interviews to occur long after a person becomes ill. CDC requests OMB...

  4. 77 FR 52740 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-08-30

    ... series of working groups comprised of local, state, and federal public health partners. Burden hours are... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention [30Day-12-12PK... days to weeks and may cause interviews to occur long after a person becomes ill. CDC requests OMB...

  5. 75 FR 70007 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-11-16

    ... collection techniques or other forms of information technology. Written comments should be received within 60... conditions, as well as leading to nicotine addiction and dependence. Furthermore, SLT use is not a safe...

  6. 77 FR 12595 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-03-01

    ... techniques or other forms of information technology. Written comments should be received within 60 days of... conditions, as well as leading to nicotine addiction and dependence. Furthermore, SLT use is not a safe...

  7. 78 FR 65323 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-10-31

    ... forms of information technology. Written comments should be received within 60 days of this notice... as leading to nicotine addiction and dependence. Furthermore, SLT use is not a safe substitute for...

  8. 78 FR 52533 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-08-23

    ... susceptibility data required on all of the healthcare-associated infection (HAI) report forms (i.e., BSI, UTI... Infection (UTI). Staff RN 57.116: Denominators for 6,000 9 3 Neonatal Intensive Care Unit (NICU). Staff RN.... Registered Nurse (Infection 57.140: Urinary Tract 250 9 27/60 Preventionist). Infection (UTI) for LTCF...

  9. 76 FR 12119 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-03-04

    ... 75 15/60 Pneumonia (PNEU) 6,000 72 32/60 Urinary Tract Infection 6,000 27 32/60 (UTI). Staff RN... Prevention 250 3 7/60 Process Measures Monthly Monitoring for LTCF. Urinary Tract Infection 250 9 30/60 (UTI...

  10. 76 FR 74064 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-11-30

    ... 75 15/60 Pneumonia (PNEU) 6,000 72 32/60 Urinary Tract Infection 6,000 27 32/60 (UTI). Staff RN... Prevention 250 3 7/60 Process Measures Monthly Monitoring for LTCF. Urinary Tract Infection 250 9 30/60 (UTI...

  11. 77 FR 65192 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-10-25

    ...). 57.114: Urinary Tract Infection (UTI). Infection Preventionist. 6,000 27 32/60 57.116: Denominators... (UTI) Registered Nurse 250 9 30/60 for LTCF. (Infection Preventionist). 57.141: Monthly Reporting Plan...

  12. 77 FR 65191 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-10-25

    ..., attitudes, and beliefs; support for NPAO-related policy/ environmental change; intentions to change NPAO... prevention communication efforts operating within the broader context of community-level change efforts. As...

  13. Atomic Act amended

    International Nuclear Information System (INIS)

    Drabova, D.

    2002-01-01

    In the paper by the chairwoman of the Czech nuclear regulatory authority, the history of Czech nuclear legislation is outlined, the reasons for the amendment of the Atomic Act (Act No. 18/1997) are explained, and the amendments themselves are highlighted. The Act No. 13/2002 of 18 December 2001 is reproduced from the official Collection of Acts of the Czech Republic in the facsimile form. The following acts were thereby amended: Atomic Act No. 18/1997, Metrology Act No. 505/1990, Public Health Protection Act No. 258/2000, and Act No. 2/1969 on the Establishment of Ministries and Other Governmental Agencies of the Czech Republic. (P.A.)

  14. [Hereditary factors in attention deficit hyperactivity disorder

    NARCIS (Netherlands)

    Fliers, E.A.; Franke, B.

    2005-01-01

    Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by concentration problems, hyperactivity and impulsivity. Disturbances in dopamine and/or noradrenalin neurotransmission are probably the underlying pathophysiological mechanisms of ADHD. Around 80% of

  15. Remediation of attention deficits in head injury.

    OpenAIRE

    Nag S; Rao S

    1999-01-01

    Head injury is associated with psychological sequelae which impair the patient′s psychosocial functioning. Information processing, attention and memory deficits are seen in head injuries of all severity. We attempted to improve deficits of focused, sustained and divided attention. The principle of overlapping sources of attention resource pools was utilised in devising the remediation programme. Tasks used simple inexpensive materials. Four head injured young adult males with post conc...

  16. Saudi Arabia: persistent but tenable deficits

    International Nuclear Information System (INIS)

    Anon.

    1996-01-01

    In this article is described the economic situation of Saudi Arabia. In a first time, Saudi Arabia drew from external reserves to finance gulf war and covered its budget deficits, then the internal debts took over. The actual strategy in order to transfer from state to private national and foreign sector a great part of new projects financing is become a necessity to control the deficits in a country where state is strongly got in debt. (N.C.). 2 tabs

  17. Magnified Neural Envelope Coding Predicts Deficits in Speech Perception in Noise.

    Science.gov (United States)

    Millman, Rebecca E; Mattys, Sven L; Gouws, André D; Prendergast, Garreth

    2017-08-09

    Verbal communication in noisy backgrounds is challenging. Understanding speech in background noise that fluctuates in intensity over time is particularly difficult for hearing-impaired listeners with a sensorineural hearing loss (SNHL). The reduction in fast-acting cochlear compression associated with SNHL exaggerates the perceived fluctuations in intensity in amplitude-modulated sounds. SNHL-induced changes in the coding of amplitude-modulated sounds may have a detrimental effect on the ability of SNHL listeners to understand speech in the presence of modulated background noise. To date, direct evidence for a link between magnified envelope coding and deficits in speech identification in modulated noise has been absent. Here, magnetoencephalography was used to quantify the effects of SNHL on phase locking to the temporal envelope of modulated noise (envelope coding) in human auditory cortex. Our results show that SNHL enhances the amplitude of envelope coding in posteromedial auditory cortex, whereas it enhances the fidelity of envelope coding in posteromedial and posterolateral auditory cortex. This dissociation was more evident in the right hemisphere, demonstrating functional lateralization in enhanced envelope coding in SNHL listeners. However, enhanced envelope coding was not perceptually beneficial. Our results also show that both hearing thresholds and, to a lesser extent, magnified cortical envelope coding in left posteromedial auditory cortex predict speech identification in modulated background noise. We propose a framework in which magnified envelope coding in posteromedial auditory cortex disrupts the segregation of speech from background noise, leading to deficits in speech perception in modulated background noise. SIGNIFICANCE STATEMENT People with hearing loss struggle to follow conversations in noisy environments. Background noise that fluctuates in intensity over time poses a particular challenge. Using magnetoencephalography, we demonstrate

  18. Ganaxolone improves behavioral deficits in a mouse model of post-traumatic stress disorder.

    Science.gov (United States)

    Pinna, Graziano; Rasmusson, Ann M

    2014-01-01

    Allopregnanolone and its equipotent stereoisomer, pregnanolone (together termed ALLO), are neuroactive steroids that positively and allosterically modulate the action of gamma-amino-butyric acid (GABA) at GABAA receptors. Levels of ALLO are reduced in the cerebrospinal fluid of female premenopausal patients with post-traumatic stress disorder (PTSD), a severe, neuropsychiatric condition that affects millions, yet is without a consistently effective therapy. This suggests that restoring downregulated brain ALLO levels in PTSD may be beneficial. ALLO biosynthesis is also decreased in association with the emergence of PTSD-like behaviors in socially isolated (SI) mice. Similar to PTSD patients, SI mice also exhibit changes in the frontocortical and hippocampal expression of GABAA receptor subunits, resulting in resistance to benzodiazepine-mediated sedation and anxiolysis. ALLO acts at a larger spectrum of GABAA receptor subunits than benzodiazepines, and increasing corticolimbic ALLO levels in SI mice by injecting ALLO or stimulating ALLO biosynthesis with a selective brain steroidogenic stimulant, such as S-norfluoxetine, at doses far below those that block serotonin reuptake, reduces PTSD-like behavior in these mice. This suggests that synthetic analogs of ALLO, such as ganaxolone, may also improve anxiety, aggression, and other PTSD-like behaviors in the SI mouse model. Consistent with this hypothesis, ganaxolone (3.75-30 mg/kg, s.c.) injected 60 min before testing of SI mice, induced a dose-dependent reduction in aggression toward a same-sex intruder and anxiety-like behavior in an elevated plus maze. The EC50 dose of ganaxolone used in these tests also normalized exaggerated contextual fear conditioning and, remarkably, enhanced fear extinction retention in SI mice. At these doses, ganaxolone failed to change locomotion in an open field test. Therefore, unlike benzodiazepines, ganaxolone at non-sedating concentrations appears to improve dysfunctional emotional

  19. Airway Clearance Techniques (ACTs)

    Medline Plus

    Full Text Available ... Therapeutics Lab Developing New Treatments The CF Foundation offers a number of resources for learning about clinical ... her father: Demonstrate and discuss common ACT therapies Offer their tips for fitting ACTs into daily life ...

  20. Airway Clearance Techniques (ACTs)

    Medline Plus

    Full Text Available ... Treatments and Therapies Airway Clearance Airway Clearance Techniques (ACTs) There are different ways to clear your airways. ... or caregiver. Older kids and adults can choose ACTs that they can do on their own. Share ...

  1. Nuclear Installations Act 1965

    International Nuclear Information System (INIS)

    1965-01-01

    This Act governs all activities related to nuclear installations in the United Kingdom. It provides for the licensing procedure for nuclear installations, the duties of licensees, the competent authorities and carriers of nuclear material in respect of nuclear occurrences, as well as for the system of third party liability and compensation for nuclear damage. The Act repeals the Nuclear Installations (Licensing and Insurance) Act 1959 and the Nuclear Installations (Amendment Act) 1965 except for its Section 17(2). (NEA) [fr

  2. Title X may get 10% funding increase despite cutbacks for deficit.

    Science.gov (United States)

    Kaeser, L

    1994-04-01

    The politics of the US budget deficit and President's Clinton proposed health budget are described. The proposed health budget included the following items and expenditure levels: Title X planning with a 10% increase to 199 million; abstinence-based programs deleted and funding directed to the Office of Adolescent Health for $6.8 million; Community Health Centers with a 1% increase to $604 million; WIC with a 12% increase to $3.7 billion; Title IIIb of the Ryan White CARE Act on AIDS prevention with a 40% increase to $67 million; National Institute of Child Heath and Human Development, including contraceptive research, with a 5% increase to $581 million; Sexually Transmitted Disease Prevention for $100 million; Breast and Cervical Cancer Screening for $78 million; and Maternal and Child Health Block Grant with a 1% increase to $679 million. Abortion funding for poor women was an item deleted from the appropriations budget for the next fiscal year, because of its inclusion in health care reform. Final funding levels may diverge greatly from Clinton's proposed budget outlined above. Appropriations subcommittees will consider funding for each of the departments. There is no certainty on how the administration will support the proposed budget, or what actions on health care reform will impact on appropriations. If the cost of health care reform is enough, it may be that other health funding will be cut. The president's budget was sent to Congress on February 7, 1994, and included mandatory entitlement programs, which are 66% of the entire federal budget, and discretionary spending, such as for family planning. The prior Bush and Reagan administrations reduced discretionary funding, and Clinton is in the awkward position of having politically supported both increased health funding and federal budget reduction. The agreement between Congress and President Clinton in 1993 to cut federal spending over the next 5 years has reduced the ability to include new spending.

  3. Effect of OROS methylphenidate on encopresis in children with attention-deficit/hyperactivity disorder.

    Science.gov (United States)

    Yılmaz, Savaş; Bilgiç, Ayhan; Hergüner, Sabri

    2014-04-01

    Although encopresis shows a high rate of comorbidity in patients with attention-deficit/hyperactivity disorder (ADHD), the etiologic origin of this relationship and the effect of ADHD drugs on encopresis are unclear. In this chart review, we explored the effect of OROS long-acting methylphenidate (MPH) treatment on encopresis in children with ADHD. We also evaluated the relationship between the clinical variables of ADHD and encopresis. The sample consisted of 21 children and adolescents (20 boys and 1 girl) with encopresis and coexisting ADHD 7-15 years of age. Their clinical characteristics and baseline (visit 1) and end of the second months' (visit 2) Conners' Parent Rating Scale (CPRS) subscores were recorded. Retrospective clinician determinations were made using the Clinical Global Impressions-Severity subscale (CGI-S) for encopresis severity and the Clinical Global Impressions-Improvement subscale (CGI-I) for encopresis response. According to the CGI-I, 14 subjects (71.4 %) showed much or very much improvement in their encopresis at the second visit. All of the CPRS scores showed a significant reduction during the second visit. No association was found between the CGI-I score and the changes in any of the CPRS scores. Baseline oppositional defiant disorder (ODD) and conduct disorder (CD) scores were correlated with the CGI-S score; however, no association was found between core ADHD symptom severity and the CGI-S score. With regard to the encopresis outcome, the baseline CD score was negatively correlated with the CGI-I score, and the baseline ODD score was prone to show a negative correlation with the CGI-I score. These results suggest that coexisting behavioral problems may be a vulnerability factor based on the severity of encopresis, and that MPH treatment may have a positive effect on encopresis in children and adolescents with ADHD.

  4. Neuroleptic-induced deficit syndrome in bipolar disorder with psychosis

    Directory of Open Access Journals (Sweden)

    Ueda S

    2016-02-01

    Full Text Available Satoshi Ueda,1 Takeshi Sakayori,1 Ataru Omori,2 Hajime Fukuta,3 Takashi Kobayashi,3 Kousuke Ishizaka,1 Tomoyuki Saijo,4 Yoshiro Okubo1 1Department of Neuropsychiatry, Nippon Medical School, Tokyo, Japan; 2Tamachuo Hospital, Tokyo, Japan; 3Kurumegaoka Hospital, Tokyo, Japan; 4Saijo Clinic, Tokyo, Japan Abstract: Neuroleptics can induce not only physical adverse effects but also mental effects that produce deficit status in thought, affect, cognition, and behavior. This condition is known as neuroleptic-induced deficit syndrome (NIDS, which includes apathy, lack of initiative, anhedonia, indifference, blunted affect, and reduced insight into disease. Although this old concept now appears almost forgotten, neuroleptics, whether typical or atypical, can make depression or bipolar disorder resemble other more refractory conditions, readily leading to mistaken diagnosis and inappropriate treatment. The authors describe three cases of NIDS superimposed on depressive phase in bipolar disorder with psychosis, where the attending psychiatrist’s failure to recognize NIDS prevented patients from receiving effective treatment and achieving remission. All cases achieved remission after reduction of neuroleptics and intensive therapy, including electroconvulsive therapy, for bipolar depression. The concept of NIDS was originally introduced for schizophrenia, and it has rarely been highlighted in other diseases. In recent years, however, atypical antipsychotics are being more often administered to patients with bipolar disorder. Psychiatrists, therefore, should also remember and exercise caution regarding NIDS in the pharmacotherapy of bipolar disorder with and without psychosis. The authors believe that the concept of NIDS needs to be reappraised in current psychiatry. Keywords: neuroleptic-induced deficit syndrome (NIDS, bipolar disorder, psychosis, atypical antipsychotics, electroconvulsive therapy

  5. Ischemia may be the primary cause of the neurologic deficits in classic migraine

    International Nuclear Information System (INIS)

    Skyhoj Olsen, T.; Friberg, L.; Lassen, N.A.

    1987-01-01

    This study investigates whether the cerebral blood flow reduction occurring in attacks of classic migraine is sufficient to cause neurologic deficits. Regional cerebral blood flow measured with the xenon 133 intracarotid injection technique was analyzed in 11 patients in whom a low-flow area developed during attacks of classic migraine. When measured with this technique, regional cerebral blood flow in focal low-flow areas will be overestimated because of the effect of scattered radiation (Compton scatter) on the recordings. In this study, this effect was particularly taken into account when evaluating the degree of blood flow reduction. During attacks of classic migraine, cerebral blood flow reductions averaging 52% were observed focally in the 11 patients. Cerebral blood flow levels known to be insufficient for normal cortical function (less than 16 to 23 mL/100 g/min) were measured in seven patients during the attacks. This was probably also the case in the remaining four patients, but the effect of scattered radiation made a reliable evaluation of blood flow impossible. It is concluded that the blood flow reduction that occurs during attacks of classic migraine is sufficient to cause ischemia and neurologic deficits. Hence, this study suggests a vascular origin of the prodromal neurologic deficits that may accompany attacks of classic migraine

  6. Analysis of Budget deficit in Romania during 2000-2013

    OpenAIRE

    Moraru Camelia; Popovici Norina

    2014-01-01

    Worldwide, over time, the years of economic crisis were defined by significant increases in the levels of budget deficits. Discussions on sizing budget deficits, financing, especially the volume of public debt became more intense, both politically and academically. The impact of budget deficit on economic growth is a common theme found in the economic policies adopted. The present paper aims to analyze the evolution of budget deficit and the structural budget deficit in Romania during 2000-20...

  7. Color perception deficits in co-existing attention-deficit/hyperactivity disorder and chronic tic disorders

    NARCIS (Netherlands)

    Roessner, V.; Banaschewski, T.; Fillmer-Otte, A.; Becker, A.; Albrecht, B.; Uebel, H.; Sergeant, J.A.; Tannock, R.; Rothenberger, A.

    2008-01-01

    Preliminary findings suggest that color perception, particularly of blue-yellow stimuli, is impaired in attention-deficit/hyperactivity disorder (ADHD) as well as in chronic tic disorders (CTD). However, these findings have been not replicated and it is unclear what these deficits mean for the

  8. Beyond Auditory Sensory Processing Deficits: Lexical Tone Perception Deficits in Chinese Children with Developmental Dyslexia

    Science.gov (United States)

    Tong, Xiuhong; Tong, Xiuli; King Yiu, Fung

    2018-01-01

    Increasing evidence suggests that children with developmental dyslexia exhibit a deficit not only at the segmental level of phonological processing but also, by extension, at the suprasegmental level. However, it remains unclear whether such a suprasegmental phonological processing deficit is due to a difficulty in processing acoustic cues of…

  9. Story Comprehension and Academic Deficits in Children with Attention Deficit Hyperactivity Disorder: What Is the Connection?

    Science.gov (United States)

    Berthiaume, Kristen S.

    2006-01-01

    Based on the reliable findings that children with attention deficit hyperactivity disorder (ADHD) have both attentional and academic difficulties, it is assumed that the attentional deficit contributes to the academic problems. In this article, existing support for a link between the attentional and academic difficulties experienced by children…

  10. Water deficit modifies the carbon isotopic composition of lipids, soluble sugars and leaves of Copaifera langsdorffii Desf. (Fabaceae

    Directory of Open Access Journals (Sweden)

    Angelo Albano da Silva Bertholdi

    2017-11-01

    Full Text Available ABSTRACT Water deficit is most frequent in forest physiognomies subjected to climate change. As a consequence, several tree species alter tissue water potential, gas exchange and production of carbon compounds to overcome damage caused by water deficiency. The working hypothesis, that a reduction in gas exchange by plants experiencing water deficit will affect the composition of carbon compounds in soluble sugars, lipids and vegetative structures, was tested on Copaifera langsdorffii. Stomatal conductance, leaf water potential, and CO2 assimilation rate declined after a period of water deficit. After rehydration, leaf water potential and leaf gas exchange did not recover completely. Water deficit resulted in 13C enrichment in leaves, soluble sugars and root lipids. Furthermore, the amount of soluble sugars and root lipids decreased after water deficit. In rehydration, the carbon isotopic composition and amount of root lipids returned to levels similar to the control. Under water deficit, 13C-enriched in root lipids assists in the adjustment of cellular membrane turgidity and avoids damage to the process of water absorption by roots. These physiological adjustments permit a better understanding of the responses of Copaifera langsdorffi to water deficit.

  11. MDMA, serotonergic neurotoxicity, and the diverse functional deficits of recreational 'Ecstasy' users.

    Science.gov (United States)

    Parrott, Andrew C

    2013-09-01

    Serotonergic neurotoxicity following MDMA is well-established in laboratory animals, and neuroimaging studies have found lower serotonin transporter (SERT) binding in abstinent Ecstasy/MDMA users. Serotonin is a modulator for many different psychobiological functions, and this review will summarize the evidence for equivalent functional deficits in recreational users. Declarative memory, prospective memory, and higher cognitive skills are often impaired. Neurocognitive deficits are associated with reduced SERT in the hippocampus, parietal cortex, and prefrontal cortex. EEG and ERP studies have shown localised reductions in brain activity during neurocognitive performance. Deficits in sleep, mood, vision, pain, psychomotor skill, tremor, neurohormonal activity, and psychiatric status, have also been demonstrated. The children of mothers who take Ecstasy/MDMA during pregnancy have developmental problems. These psychobiological deficits are wide-ranging, and occur in functions known to be modulated by serotonin. They are often related to lifetime dosage, with light users showing slight changes, and heavy users displaying more pronounced problems. In summary, abstinent Ecstasy/MDMA users can show deficits in a wide range of biobehavioral functions with a serotonergic component. Copyright © 2013 Elsevier Ltd. All rights reserved.

  12. Deficits in agency in schizophrenia, and additional deficits in body image, body schema and internal timing, in passivity symptoms.

    Directory of Open Access Journals (Sweden)

    Kyran Trent Graham

    2014-09-01

    Full Text Available Individuals with schizophrenia, particularly those with passivity symptoms, may not feel in control of their actions, believing them to be controlled by external agents. Cognitive operations that contribute to these symptoms may include abnormal processing in agency, as well as body representations that deal with body schema and body image. However, these operations in schizophrenia are not fully understood, and the questions of general versus specific deficits in individuals with different symptom profiles remain unanswered. Using the projected hand illusion (a digital video version of the rubber hand illusion with syn-chronous and asynchronous stroking (500 ms delay, and a hand laterality judgment task, we assessed sense of agency, body image and body schema in 53 people with clinically stable schizophrenia (with a current, past, and no history of passivity symptoms and 48 healthy controls. The results revealed a stable trait in schizophrenia with no difference be-tween clinical subgroups (sense of agency, and some quantitative (specific differences de-pending on the passivity symptom profile (body image and body schema. Specifically, a reduced sense of self-agency was a common feature of all clinical subgroups. However, subgroup comparisons showed that individuals with passivity symptoms (both current and past had significantly greater deficits on tasks assessing body image and body schema, relative to the other groups. In addition, patients with current passivity symptoms failed to demonstrate the normal reduction in body illusion typically seen with a 500 ms delay in visual feedback (asynchronous condition, suggesting internal timing problems. Altogether, the results underscore self-abnormalities in schizophrenia, provide evidence for both trait abnormalities and state changes specific to passivity symptoms, and point to a role for internal timing deficits as a mechanistic explanation for external cues becoming a possible source of self

  13. THE IMPLICATIONS OF GROSS FIXED CAPITAL AND UNEMPLOYMENT RATE ON GENERAL GOVERNMENT DEFICIT. EMPIRICAL STUDY AT THE EUROPEAN LEVEL

    Directory of Open Access Journals (Sweden)

    Mihai Carp

    2010-12-01

    Full Text Available In this paper we have evaluated the influence of the modification of public investment level and unemployment rate on the general government deficit at the European Union level. We have created a regression model that shows that a sustained and increased investment policy and the reduction of unemployment rate have a favorable effect on the objective of minimizing the budget deficit. In the last years European Union’s countries had to face a difficult problem concerning fiscal policy. They had to make public investments to stimulate economic growth and, in the same time, they had to meet the convergence criteria’s of public deficit. On the other hand, EU has to deal with a higher rate of unemployment. Through our model we try to see how European Union countries should implement their political strategies on unemployment and investment with the main objective of reducing the general government deficit.

  14. Psychometric properties of Persian version of the Sustained Auditory Attention Capacity Test in children with attention deficit-hyperactivity disorder.

    Science.gov (United States)

    Soltanparast, Sanaz; Jafari, Zahra; Sameni, Seyed Jalal; Salehi, Masoud

    2014-01-01

    The purpose of the present study was to evaluate the psychometric properties (validity and reliability) of the Persian version of the Sustained Auditory Attention Capacity Test in children with attention deficit hyperactivity disorder. The Persian version of the Sustained Auditory Attention Capacity Test was constructed to assess sustained auditory attention using the method provided by Feniman and colleagues (2007). In this test, comments were provided to assess the child's attentional deficit by determining inattention and impulsiveness error, the total scores of the sustained auditory attention capacity test and attention span reduction index. In the present study for determining the validity and reliability of in both Rey Auditory Verbal Learning test and the Persian version of the Sustained Auditory Attention Capacity Test (SAACT), 46 normal children and 41 children with Attention Deficit Hyperactivity (ADHD), all right-handed and aged between 7 and 11 of both genders, were evaluated. In determining convergent validity, a negative significant correlation was found between the three parts of the Rey Auditory Verbal Learning test (first, fifth, and immediate recall) and all indicators of the SAACT except attention span reduction. By comparing the test scores between the normal and ADHD groups, discriminant validity analysis showed significant differences in all indicators of the test except for attention span reduction (pAttention Capacity test has good validity and reliability, that matches other reliable tests, and it can be used for the identification of children with attention deficits and if they suspected to have Attention Deficit Hyperactivity Disorder.

  15. Finding optimal exact reducts

    KAUST Repository

    AbouEisha, Hassan M.

    2014-01-01

    The problem of attribute reduction is an important problem related to feature selection and knowledge discovery. The problem of finding reducts with minimum cardinality is NP-hard. This paper suggests a new algorithm for finding exact reducts

  16. Neuropsychological deficits in patients with Lyme borreliosis

    Directory of Open Access Journals (Sweden)

    Katja Pruša

    2001-09-01

    Full Text Available Slovenia is an endemic area for Lyme borreliosis, a disease that affects many organic systems. Decline in cognitive abilities and emotional changes can appear in acute and chronic stage of the disease beside somatic difficulties. Early antibiotic therapy is of great importance in recovery. Attention and concentration deficits, memory deficits, impaired executive functioning, depression and other symptoms reduce work efficiency and life quality of people with Lyme borreliosis. Neuropsychological deficits can be explained with central nervous system impairment and partly also with reactive psychological factors. On account of symptomatic complexity, broad differential diagnostic and unreliable diagnostic technology neuropsychological evaluation can help to correctly diagnose and accurately treat this disease, and thus to enable appropriate cognitive rehabilitation and psychotherapeutic assistance.

  17. Neural Substrates of Auditory Emotion Recognition Deficits in Schizophrenia.

    Science.gov (United States)

    Kantrowitz, Joshua T; Hoptman, Matthew J; Leitman, David I; Moreno-Ortega, Marta; Lehrfeld, Jonathan M; Dias, Elisa; Sehatpour, Pejman; Laukka, Petri; Silipo, Gail; Javitt, Daniel C

    2015-11-04

    Deficits in auditory emotion recognition (AER) are a core feature of schizophrenia and a key component of social cognitive impairment. AER deficits are tied behaviorally to impaired ability to interpret tonal ("prosodic") features of speech that normally convey emotion, such as modulations in base pitch (F0M) and pitch variability (F0SD). These modulations can be recreated using synthetic frequency modulated (FM) tones that mimic the prosodic contours of specific emotional stimuli. The present study investigates neural mechanisms underlying impaired AER using a combined event-related potential/resting-state functional connectivity (rsfMRI) approach in 84 schizophrenia/schizoaffective disorder patients and 66 healthy comparison subjects. Mismatch negativity (MMN) to FM tones was assessed in 43 patients/36 controls. rsfMRI between auditory cortex and medial temporal (insula) regions was assessed in 55 patients/51 controls. The relationship between AER, MMN to FM tones, and rsfMRI was assessed in the subset who performed all assessments (14 patients, 21 controls). As predicted, patients showed robust reductions in MMN across FM stimulus type (p = 0.005), particularly to modulations in F0M, along with impairments in AER and FM tone discrimination. MMN source analysis indicated dipoles in both auditory cortex and anterior insula, whereas rsfMRI analyses showed reduced auditory-insula connectivity. MMN to FM tones and functional connectivity together accounted for ∼50% of the variance in AER performance across individuals. These findings demonstrate that impaired preattentive processing of tonal information and reduced auditory-insula connectivity are critical determinants of social cognitive dysfunction in schizophrenia, and thus represent key targets for future research and clinical intervention. Schizophrenia patients show deficits in the ability to infer emotion based upon tone of voice [auditory emotion recognition (AER)] that drive impairments in social cognition

  18. Consequences of the Budget Deficit in the Current Crisis in Romania. Implications on the Labor Market

    Directory of Open Access Journals (Sweden)

    Gabriela MOLĂNESCU

    2011-02-01

    Full Text Available In the current economic activity conditions, in which the need of financial resources is usually higher than the existing funds, the elaborations of budgets at any level is one of the primary issues, particularly as regards the principle of budgetary balance. Approaches regarding sizing budgets deficits, means of financing and particularly sizing public debt get a series of touches of precise nature for different economies. Actual economic, financial, social and administrative conditions put up a series of problems which impose an extremely serious approach of the potential adverse impact by sizing of budget deficits and public debt over the real possibilities of noninflationary financing. In Romania, in the highly complex framework in which the economic activity takes place, in the attempt to show the place held by the budget deficit, a special role is assigned to determine the share of public financial deficit in the consolidated budget revenue and expenditure. Currently, knowledge and concern for reducing the budget deficit are still of great importance, especially as Romania is facing great difficulties in economic development. Amid deepening structural crisis phenomena, increasing budget deficits financed over a non-inflationary limits comes as an additional factor that contributes to imbalances of the economy. In addition, where budgetary expenditures are targeted to satisfy, primary, the redistribution function and to state subsidies, because of the lack of a real multiplier coefficient, the state budget deficit worsens. Influences such as introducing economic disturbance in the mechanisms which cause them to increase budget deficits can be summarized and grouped into two broad categories: economic influences and psychological influences. Regarding economic influences, we can say that they act strongly and strictly determined by how meanings used to cover budget deficit. The modalities used are subject to an analysis by direct or indirect

  19. The history of attention deficit hyperactivity disorder

    Science.gov (United States)

    Reichl, Susanne; Lange, Katharina M.; Tucha, Lara; Tucha, Oliver

    2010-01-01

    The contemporary concept of attention deficit hyperactivity disorder (ADHD) as defined in the DSM-IV-TR (American Psychiatric Association 2000) is relatively new. Excessive hyperactive, inattentive, and impulsive children have been described in the literature since the nineteenth century. Some of the early depictions and etiological theories of hyperactivity were similar to current descriptions of ADHD. Detailed studies of the behavior of hyperactive children and increasing knowledge of brain function have changed the concepts of the fundamental behavioral and neuropathological deficits underlying the disorder. This article presents an overview of the conceptual history of modern-day ADHD. PMID:21258430

  20. The deficit syndrome of schizophrenia: towards heterogeneity.

    Science.gov (United States)

    Thibaut, F; Petit, M

    1997-01-01

    Since the turn of the century, psychiatrists have been concerned with both the unity and diversity of schizophrenia. From these early descriptions until now, many authors have attempted to delineate clinically meaningful subtypes within this disorder. In this connection, negative/positive subtyping has generated great interest. Carpenter and his team have emphasized the origin of the negative symptoms observed. They have proposed that primary enduring negative symptoms should be distinguished from transient negative symptoms resulting from treatment, depression or social deprivation and should be termed deficit symptoms. The validity of this subtyping is supported by clinical, biochemical or electrophysiological studies showing differences between deficit and nondeficit patients.

  1. Breast Reduction Surgery

    Science.gov (United States)

    ... considering breast reduction surgery, consult a board-certified plastic surgeon. It's important to understand what breast reduction surgery entails — including possible risks and complications — as ...

  2. Evaluation Yield of Sunflower (Farrokh cultivar under Effects of Conventional Deficit Irrigation and Partial Root Zone Drying

    Directory of Open Access Journals (Sweden)

    A. Rezaei Estakhroeih

    2015-06-01

    Full Text Available Water shortage is the most important factors on crop production in the world. Several methods of deficit irrigation are solutions for reduction of irrigation water. To understand the effects of conventional deficit irrigation and partial root zone drying treatments on yield, yield components and water use efficiency of sunflower (Farrokh cultivar, one study was carried out. The research was conducted on Shahid Bahonar University of Kerman in the spring of 2011. A factorial experiment in a randomized complete block design with one control (full irrigation and 18 deficit irrigation treatments in three replications was considered. Deficit irrigation treatments were: conventional deficit irrigation (irrigation with %80, %60 and %40 ETP and partial root zone drying (irrigation with %80, %60 and %40 ETP. Every deficit irrigation treatment was conducted in three growth stage of sunflower (all periods of growth, vegetative growth stage and reproductive growth stage.The results showed that the conventional deficit irrigation treatments (irrigation with 80% ETP in vegetative growth had the highest plant height, leaf area, leaf area index and head diameter. Also, the maximum biological yield equal to49054, maximum grain yield is equal to 9934/3 and maximum oil yield is equal to 2441/2 kg per hectare in the conventional deficit irrigation treatments (irrigation with 80% ETP in vegetative growth occurred.The highest water use efficiency for grain yield is equal to 1/46,forbiological yield equal to7/21 and for dry forage yield is equal 5/7 kilograms per cubic meter of water. According to results,conventional deficit irrigation (irrigation with %80, %60 and %40 ETP is recommended on based.

  3. Radioactive Substances Act 1960

    International Nuclear Information System (INIS)

    1960-01-01

    This Act regulates the keeping and use of radioactive material and makes provision for the disposal and storage of radioactive waste in the United Kingdom. It provides for a licensing system for such activities and for exemptions therefrom, in particular as concerns the United Kingdom Atomic Energy Authority. The Act repeals Section 4(5) of the Atomic Energy Authority Act, 1954 which made temporary provision for discharge of waste on or from premises occupied by the Authority. (NEA) [fr

  4. Learning dialog act processing

    OpenAIRE

    Wermter, Stefan; Löchel, Matthias

    1996-01-01

    In this paper we describe a new approach for learning dialog act processing. In this approach we integrate a symbolic semantic segmentation parser with a learning dialog act network. In order to support the unforeseeable errors and variations of spoken language we have concentrated on robust data-driven learning. This approach already compares favorably with the statistical average plausibility method, produces a segmentation and dialog act assignment for all utterances in a robust manner,...

  5. Airway Clearance Techniques (ACTs)

    Medline Plus

    Full Text Available ... Reform Could Impact People With CF The Preserving Employee Wellness Programs Act Our Advocacy Work Advocacy Achievements Advocacy News Briefings, Testimonies, and Regulatory ...

  6. Radiological Protection Act 1970

    International Nuclear Information System (INIS)

    1970-01-01

    This Act provides for the establishment of a Radiological Protection Board to undertake research and advise on protection from radiation hazards. Its functions include provision of advice to Government departments with responsibilities in relation to protection of sectors of the community or the community as a whole against the hazards of ionizing radiation. The Act, which lays down that the Board shall replace certain departments concerned with radiation protection, repeals several Sections of the Radioactive Substances Act 1948 and the Science and Technology Act 1965. (NEA) [fr

  7. 25 CFR 700.33 - Act (The Act).

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false Act (The Act). 700.33 Section 700.33 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES General Policies and Instructions Definitions § 700.33 Act (The Act). (a) The Act. The Act is Pub. L. 93-531, (88 Stat...

  8. Guanfacine Extended Release in Children and Adolescents with Attention-Deficit/Hyperactivity Disorder: A Placebo-Controlled Trial

    Science.gov (United States)

    Sallee, Floyd R.; McGough, James; Wigal, Tim; Donahue, Jessica; Lyne, Andrew; Biederman, Joseph

    2009-01-01

    A double-blind, 9-week, randomized trial was done to compare the efficacy of guanfacine extended release (GXR) with a placebo in treating children and adolescents with attention-deficit/hyperactivity disorders (ADHD). Results find a significant reduction in ADHD from baseline to endpoint for all daily doses of GXR which were measured at 1-, 2-,…

  9. Traumatic Posterior Atlantoaxial Dislocation Without Associated Fracture but With Neurological Deficit

    Science.gov (United States)

    Xu, Yong; Li, Feng; Guan, Hanfeng; Xiong, Wei

    2015-01-01

    Abstract Posterior atlantoaxial dislocation without odontoid fracture is extremely rare and often results in fatal spinal cord injury. According to the reported literature, all cases presented mild or no neurologic deficit, with no definite relation to upper spinal cord injury. Little is reported about traumatic posterior atlantoaxial dislocation, with incomplete quadriplegia associated with a spinal cord injury. We present a case of posterior atlantoaxial dislocation without associated fracture, but with quadriplegia, and accompanying epidural hematoma and subarachnoid hemorrhage. The patient underwent gentle traction in the neutral position until repeated cranial computed tomography revealed no progression of the epidural hematoma. Thereafter, the atlantoaxial dislocation was reduced by using partial odontoidectomy via a video-assisted transcervical approach and maintained with posterior polyaxial screw-rod constructs and an autograft. Neurological status improved immediately after surgery, and the patient recovered completely after 1 year. Posterior fusion followed by closed reduction is the superior strategy for posterior atlantoaxial dislocation without odontoid fracture, according to literature. But for cases with severe neurological deficit, open reduction may be the safest choice to avoid the lethal complication of overdistraction of the spinal cord. Also, open reduction and posterior srew-rod fixation are safe and convenient strategies in dealing with traumatic posterior atlantoaxial dislocation patients with neurological deficit. PMID:26512572

  10. [A core deficit in Parkinson disease?].

    Science.gov (United States)

    Benítez-Burraco, A; Herrera, E; Cuetos, F

    2016-05-01

    Parkinson disease is a neurodegenerative condition involving motor, cognitive, and linguistic deficits. It is important to know why all these different deficits co-occur in the affected people. This paper aims to clarify whether these comorbid deficits result from the selective impairment of a computational primitive, namely, a context-sensitive computational ability according to Chomsky's Hierarchy (a well-established research tool in comparative neuroscience). A total of 15 medicated subjects with Parkinson disease and 15 controls were selected. They were matched in age and education. A battery of tasks was designed to test 3 different domains (motor capacities, cognition, and language) and 2 different computational abilities (context-free and context-sensitive operations). Significant differences between groups were observed only regarding the linguistic task involving context-sensitive computations (correferences). The observed deficits in our patients with Parkinson disease cannot be explained in terms of the selective impairment of one only unspecific, low-level computational process. At the same time, differences between patients and controls are expected to be greater if the former are not medicated. Moreover, we should pursue in the search of (this kind of) computational primitives than can be selectively impaired in people with Parkinson disease, because they may help to achieve an earlier diagnosis of this condition. Copyright © 2014 Sociedad Española de Neurología. Published by Elsevier España, S.L.U. All rights reserved.

  11. Intervertebral Disc Characteristic on Progressive Neurological Deficit

    Directory of Open Access Journals (Sweden)

    Farid Yudoyono

    2017-09-01

    Full Text Available Objective: To examine the intervertebral disc characteristic on magnetic resonance imaging (MRI in lumbar herniated disc (LHD patients with progressive neurological deficit. Methods: Patients were collected retrospectively from Dr. Hasan Sadikin General Hospital Database from 2011–2013 with LHD, had neurological deficit such as radiculopathy and cauda equine syndrome for less than four weeks with a positive sign confirmed by neurological examination and confirmatory with MRI examination. Results: A total of 14 patients with lumbar herniated disc disease (10 males, 4 females suffered from progressive neurological deficit with an average age of (52.07±10.9 years old. Early disc height was 9.38±0.5 mm and progressive neurological deficit state disc height was 4.03±0.53 mm, which were significantly different statisticaly (p<0.01. Symptoms of radiculopathy were seen in 11 patients and cauda equine syndrome in three patients. Modic changes grade 1 was found in five patients, grade 2 in eight patients,grade 3 in one patient, Pfirmman grade 2 in eleven patients and grade 3 in three patients. Thecal sac compression 1/3 compression was seen in four patients and 2/3 compression in ten patients. Conclusions: Neurosurgeon should raise concerns on the characteristic changes of intervertebral disc in magnetic resonance imaging examination to avoid further neural injury in lumbar herniated disc patients.

  12. Stigma in attention deficit hyperactivity disorder

    NARCIS (Netherlands)

    Müller, Kathi; Fuermaier, Anselm B M; Koerts, Janneke; Tucha, Lara

    Attention deficit hyperactivity disorder (ADHD) is a frequently diagnosed disorder in child- and adulthood with a high impact affecting multiple facets of social life. Therefore, patients suffering from ADHD are at high risk to be confronted with stigma, prejudices, and discrimination. A review of

  13. Nature, Nurture, and Attention Deficit Hyperactivity Disorder.

    Science.gov (United States)

    Faraone, Stephen V.; Biederman, Joseph

    2000-01-01

    Comments on Joseph's review of the genetics of attention deficit disorder, demonstrating errors of scientific logic and oversight of relevant research in Joseph's argument. Argues for the validity of twin studies in supporting a genetic link for ADHD and for the complementary role of nature and nurture in the etiology of the disorder. (JPB)

  14. Medication Treatment for Attention Deficit Hyperactivity Disorder

    Science.gov (United States)

    Ryan, Joseph B.; Katsiyannis, Antonis; Hughes, Elizabeth M.

    2011-01-01

    Attention deficit hyperactivity disorder (ADHD) has become the most commonly diagnosed psychiatric disorder among school-age children. For more than half a century, physicians have prescribed medications to help manage behaviors such as hyperactivity, impulsivity, and inattention. Today, there is a growing consensus that ADHD is a biologically…

  15. Reducing the Deficit: Spending and Revenue Options

    Science.gov (United States)

    1994-03-01

    357 B SPENDING OPTIONS BY BUDGET FUNCION ...... 363 TABLES 1. Baseline Deficit Projections, Fiscal Years 1993-2004...direct control of the Congress. abled beneficiaries and beneficiaries with end-stage renal disease. Nonhealth changes enacted in The total that is

  16. ATTENTION DEFICIT/HYPERACTIVITY DISORDER (ADHD)

    African Journals Online (AJOL)

    Enrique

    People who suffer from ADHD are far more likely than normal to drop out of school (32 ... secondary to learning disabilities, partial sensory deficits or even low cognitive ... bad days (Fig. 3), which can lead to frustration for teachers, parents and the child, as there is always the feeling that ... boys who often present very young.

  17. Invest to Improve: The Cybersecurity Talent Deficit

    Science.gov (United States)

    Business-Higher Education Forum, 2017

    2017-01-01

    "Invest to Improve: The Cybersecurity Talent Deficit" provides recommendations for cybersecurity stakeholders--employers, government agencies, and higher education institutions--to enable regional partnerships to meet today's cybersecurity skills needs. This report combines data from a 2017 Gallup survey of business executives and higher…

  18. Linguistic coding deficits in foreign language learners.

    Science.gov (United States)

    Sparks, R; Ganschow, L; Pohlman, J

    1989-01-01

    As increasing numbers of colleges and universities require a foreign language for graduation in at least one of their degree programs, reports of students with difficulties in learning a second language are multiplying. Until recently, little research has been conducted to identify the nature of this problem. Recent attempts by the authors have focused upon subtle but ongoing language difficulties in these individuals as the source of their struggle to learn a foreign language. The present paper attempts to expand upon this concept by outlining a theoretical framework based upon a linguistic coding model that hypothesizes deficits in the processing of phonological, syntactic, and/or semantic information. Traditional psychoeducational assessment batteries of standardized intelligence and achievement tests generally are not sensitive to these linguistic coding deficits unless closely analyzed or, more often, used in conjunction with a more comprehensive language assessment battery. Students who have been waived from a foreign language requirement and their proposed type(s) of linguistic coding deficits are profiled. Tentative conclusions about the nature of these foreign language learning deficits are presented along with specific suggestions for tests to be used in psychoeducational evaluations.

  19. Financing the U.S. Trade Deficit

    National Research Council Canada - National Science Library

    Jackson, James K

    2007-01-01

    The U.S. merchandise trade deficit is a part of the overall U.S. balance of payments, a summary statement of all economic transactions between the residents of the United States and the rest of the world, during a given period of time...

  20. Attention Deficit Hyperactivity Disorder: A Parent's Perspective.

    Science.gov (United States)

    Thompson, Anna M.

    1996-01-01

    A parent and educator who has spent the past 10 years struggling to help her own ADHD (attention deficit-hyperactivity disorder) child offers suggestions for managing the challenges facing such children and enhancing the quality of their lives. Since drug regimens have limitations, parents need to read appropriate literature and receive…

  1. Primary School Teacher's knowledge towards Attention Deficit ...

    African Journals Online (AJOL)

    The work of the teacher becomes much more demanding when some learners have Attention-Deficit/Hyperactivity Disorder (ADHD), as their problems with attention span, impulse control and activity level frequently interfere with activities in the classroom and socially. This study revealed the teachers good knowledge about ...

  2. Magnesium supplementation in children with attention deficit ...

    African Journals Online (AJOL)

    Background: Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder with associated mineral deficiency. Aim: To assess magnesium level in ADHD children and compare it to the normal levels in children. Then, to detect the effect of magnesium supplementation as an add on therapy, ...

  3. Did goethe describe attention deficit hyperactivity disorder?

    Science.gov (United States)

    Bonazza, Sara; Scaglione, Cesa; Poppi, Massimo; Rizzo, Giovanni

    2011-01-01

    As early as 1846, the typical symptoms of attention deficit hyperactivity disorder (ADHD) were described by Heinrich Hoffmann (1809-1894). However, in Goethe's masterpiece Faust (1832), the character of Euphorion strongly suggests ADHD diagnosis. Copyright © 2011 S. Karger AG, Basel.

  4. Heterogeneity of Developmental Dyscalculia: Cases with Different Deficit Profiles.

    Science.gov (United States)

    Träff, Ulf; Olsson, Linda; Östergren, Rickard; Skagerlund, Kenny

    2016-01-01

    Developmental Dyscalculia (DD) has long been thought to be a monolithic learning disorder that can be attributed to a specific neurocognitive dysfunction. However, recent research has increasingly recognized the heterogeneity of DD, where DD can be differentiated into subtypes in which the underlying cognitive deficits and neural dysfunctions may differ. The aim was to further understand the heterogeneity of developmental dyscalculia (DD) from a cognitive psychological perspective. Utilizing four children (8-9 year-old) we administered a comprehensive cognitive test battery that shed light on the cognitive-behavioral profile of each child. The children were compared against norm groups of aged-matched peers. Performance was then contrasted against predominant hypotheses of DD, which would also give insight into candidate neurocognitive correlates. Despite showing similar mathematical deficits, these children showed remarkable interindividual variability regarding cognitive profile and deficits. Two cases were consistent with the approximate number system deficit account and also the general magnitude-processing deficit account. These cases showed indications of having domain-general deficits as well. One case had an access deficit in combination with a general cognitive deficit. One case suffered from general cognitive deficits only. The results showed that DD cannot be attributed to a single explanatory factor. These findings support a multiple deficits account of DD and suggest that some cases have multiple deficits, whereas other cases have a single deficit. We discuss a previously proposed distinction between primary DD and secondary DD, and suggest hypotheses of dysfunctional neurocognitive correlates responsible for the displayed deficits.

  5. Infinitary Combinatory Reduction Systems: Normalising Reduction Strategies

    NARCIS (Netherlands)

    Ketema, J.; Simonsen, Jakob Grue

    2010-01-01

    We study normalising reduction strategies for infinitary Combinatory Reduction Systems (iCRSs). We prove that all fair, outermost-fair, and needed-fair strategies are normalising for orthogonal, fully-extended iCRSs. These facts properly generalise a number of results on normalising strategies in

  6. Robotic identification of kinesthetic deficits after stroke.

    Science.gov (United States)

    Semrau, Jennifer A; Herter, Troy M; Scott, Stephen H; Dukelow, Sean P

    2013-12-01

    Kinesthesia, the sense of body motion, is essential to proper control and execution of movement. Despite its importance for activities of daily living, no current clinical measures can objectively measure kinesthetic deficits. The goal of this study was to use robotic technology to quantify prevalence and severity of kinesthetic deficits of the upper limb poststroke. Seventy-four neurologically intact subjects and 113 subjects with stroke (62 left-affected, 51 right-affected) performed a robot-based kinesthetic matching task with vision occluded. The robot moved the most affected arm at a preset speed, direction, and magnitude. Subjects were instructed to mirror-match the movement with their opposite arm (active arm). A large number of subjects with stroke were significantly impaired on measures of kinesthesia. We observed impairments in ability to match movement direction (69% and 49% impaired for left- and right-affected subjects, respectively) and movement magnitude (42% and 31%). We observed impairments to match movement speed (32% and 27%) and increased response latencies (48% and 20%). Movement direction errors and response latencies were related to clinical measures of function, motor recovery, and dexterity. Using a robotic approach, we found that 61% of acute stroke survivors (n=69) had kinesthetic deficits. Additionally, these deficits were highly related to existing clinical measures, suggesting the importance of kinesthesia in day-to-day function. Our methods allow for more sensitive, accurate, and objective identification of kinesthetic deficits after stroke. With this information, we can better inform clinical treatment strategies to improve poststroke rehabilitative care and outcomes.

  7. Regulated deficit irrigation alters anthocyanins, tannins and sensory properties of cabernet sauvignon grapes and wines.

    Science.gov (United States)

    Casassa, Luis Federico; Keller, Markus; Harbertson, James F

    2015-04-29

    Four regulated deficit irrigation (RDI) regimes were applied to Cabernet Sauvignon grapes, which were analyzed for phenolics and also made into wine over three consecutive growing seasons. Relative to an industry standard regime (IS), yield was reduced over the three years by 37% in a full-deficit (FD) regime and by 18% in an early deficit (ED) regime, whereas no yield reduction occurred with a late deficit (LD) regime. Relative to IS, skin anthocyanin concentration (fresh weight basis) was 18% and 24% higher in ED and FD, respectively, whereas no effect was seen in LD. Seed tannin concentration was 3% and 8% higher in ED and FD, respectively, relative to the other two RDI regimes, whereas seed tannin content (amount per berry) was higher in IS than in FD. There were no practically relevant effects on the basic chemistry of the wines. The finished wines showed concentrations of tannins and anthocyanins that generally mirrored observed differences in skin and seed phenolic concentrations, although these were amplified in FD wines. Descriptive sensory analysis of the 2008 wines showed that FD wines were the most saturated in color, with higher purple hue, roughness, dryness and harshness, followed by ED wines, whereas IS and LD wines were less saturated in color and with higher brown and red hues. Overall, FD and ED seemed to yield fruit and wine with greater concentrations of phenolics than IS and LD, with the additional advantage of reducing water usage. However, these apparent benefits need to be balanced out with reductions in crop yields and potential long-term effects associated with pre-véraison water deficits.

  8. Regulated Deficit Irrigation Alters Anthocyanins, Tannins and Sensory Properties of Cabernet Sauvignon Grapes and Wines

    Directory of Open Access Journals (Sweden)

    Luis Federico Casassa

    2015-04-01

    Full Text Available Four regulated deficit irrigation (RDI regimes were applied to Cabernet Sauvignon grapes, which were analyzed for phenolics and also made into wine over three consecutive growing seasons. Relative to an industry standard regime (IS, yield was reduced over the three years by 37% in a full-deficit (FD regime and by 18% in an early deficit (ED regime, whereas no yield reduction occurred with a late deficit (LD regime. Relative to IS, skin anthocyanin concentration (fresh weight basis was 18% and 24% higher in ED and FD, respectively, whereas no effect was seen in LD. Seed tannin concentration was 3% and 8% higher in ED and FD, respectively, relative to the other two RDI regimes, whereas seed tannin content (amount per berry was higher in IS than in FD. There were no practically relevant effects on the basic chemistry of the wines. The finished wines showed concentrations of tannins and anthocyanins that generally mirrored observed differences in skin and seed phenolic concentrations, although these were amplified in FD wines. Descriptive sensory analysis of the 2008 wines showed that FD wines were the most saturated in color, with higher purple hue, roughness, dryness and harshness, followed by ED wines, whereas IS and LD wines were less saturated in color and with higher brown and red hues. Overall, FD and ED seemed to yield fruit and wine with greater concentrations of phenolics than IS and LD, with the additional advantage of reducing water usage. However, these apparent benefits need to be balanced out with reductions in crop yields and potential long-term effects associated with pre-véraison water deficits.

  9. Visual sensory processing deficits in patients with bipolar disorder revealed through high-density electrical mapping.

    LENUS (Irish Health Repository)

    Yeap, Sherlyn

    2009-11-01

    BACKGROUND: Etiological commonalities are apparent between bipolar disorder and schizophrenia. For example, it is becoming clear that both populations show similar electrophysiological deficits in the auditory domain. Recent studies have also shown robust visual sensory processing deficits in patients with schizophrenia using the event-related potential technique, but this has not been formally tested in those with bipolar disorder. Our goal here was to assess whether early visual sensory processing in patients with bipolar disorder, as indexed by decreased amplitude of the P1 component of the visual evoked potential (VEP), would show a similar deficit to that seen in those with schizophrenia. Since the P1 deficit has already been established as an endophenotype in schizophrenia, a finding of commonality between disorders would raise the possibility that it represents a measure of common genetic liability. METHODS: We visually presented isolated-check stimuli to euthymic patients with a diagnosis of bipolar disorder and age-matched healthy controls within a simple go\\/no-go task and recorded VEPs using high-density (72-channel) electroencephalography. RESULTS: The P1 VEP amplitude was substantially reduced in patients with bipolar disorder, with an effect size of f = 0.56 (large according to Cohen\\'s criteria). LIMITATIONS: Our sample size was relatively small and as such, did not allow for an examination of potential relations between the physiologic measures and clinical measures. CONCLUSION: This reduction in P1 amplitude among patients with bipolar disorder represents a dysfunction in early visual processing that is highly similar to that found repeatedly in patients with schizophrenia and their healthy first-degree relatives. Since the P1 deficit has been related to susceptibility genes for schizophrenia, our results raise the possibility that the deficit may in fact be more broadly related to the development of psychosis and that it merits further

  10. Oculomotor Anomalies in Attention-Deficit/Hyperactivity Disorder: Evidence for Deficits in Response Preparation and Inhibition

    Science.gov (United States)

    Mahone, E. Mark; Mostofsky, Stewart H.; Lasker, Adrian G.; Zee, David; Denckla, Martha B.

    2009-01-01

    Girls, but not boys, with attention deficit hyperactivity disorder (ADHD) have significantly longer visually guided saccades latencies. It is found that sex differences in children with ADHD extend beyond symptom presentation to the development of oculomotor control.

  11. Marine Mammal Protection Act

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Marine Mammal Protection Act (MMPA or Act) prohibits, with certain exceptions, the "take" of marine mammals in U.S. waters and by U.S. citizens on the high seas,...

  12. Collective speech acts

    NARCIS (Netherlands)

    Meijers, A.W.M.; Tsohatzidis, S.L.

    2007-01-01

    From its early development in the 1960s, speech act theory always had an individualistic orientation. It focused exclusively on speech acts performed by individual agents. Paradigmatic examples are ‘I promise that p’, ‘I order that p’, and ‘I declare that p’. There is a single speaker and a single

  13. Americans with Disabilities Act.

    Science.gov (United States)

    Kaesberg, Mary Ann; Murray, Kenneth T.

    1994-01-01

    Presents a 35-item checklist of practical activities for school district compliance with the Americans with Disabilities Act (ADA). The checklist is based on ADA statutes, other civil rights legislation and litigation, as well as pertinent regulations and the legislative history of the act contained in the Congressional Record. (MLF)

  14. Radiation emitting devices act

    International Nuclear Information System (INIS)

    1970-01-01

    This Act, entitled the Radiation Emitting Devices Act, is concerned with the sale and importation of radiation emitting devices. Laws relating to the sale, lease or import, labelling, advertising, packaging, safety standards and inspection of these devices are listed as well as penalties for any person who is convicted of breaking these laws

  15. Nuclear Installations Act 1969

    International Nuclear Information System (INIS)

    1969-01-01

    The purpose of this Act is to amend the Nuclear Installations Act 1965 to bring it into full compliance with the international conventions on nuclear third party liability to which the United Kingdom is a Signatory, namely, the Paris Convention, the Brussels Supplementary Convention and the Vienna Convention. (NEA) [fr

  16. Attention-Deficit / Hyperactivity Disorder (ADHD): Data and Statistics

    Science.gov (United States)

    ... Search Form Controls Cancel Submit Search the CDC Attention-Deficit / Hyperactivity Disorder (ADHD) Note: Javascript is disabled or ... claims to understand diagnosis and treatment patterns for Attention-Deficit/Hyperactivity Disorder (ADHD). On this page you can ...

  17. Children and Adults with Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    ... Renew CHADD Annual Conference Children and Adults with Attention-Deficit/Hyperactivity Disorder (CHADD), is a national nonprofit organization ... ADHD community. © 2017 by Children and Adults with Attention-Deficit/Hyperactivity Disorder (CHADD). All Rights Reserved. Press Privacy ...

  18. Persistence of attention deficit/hyperactivity disorder into adulthood ...

    African Journals Online (AJOL)

    Persistence of attention deficit/hyperactivity disorder into adulthood: A study conducted on parents of children diagnosed with attention deficit/hyperactivity disorder. ... 10, No 1 (2007) >. Log in or Register to get access to full text downloads.

  19. Attention Deficit Hyperactivity Disorder and Tuberous Sclerosis Complex

    Science.gov (United States)

    ... Privacy Policy Sitemap Learn Engage Donate About TSC Attention Deficit Hyperactivity Disorder and TSC What is ADHD? Attention Deficit Hyperactivity Disorder (ADHD) is a common neurobehavioral disorder. It is ...

  20. The Double-Deficit Hypothesis in Spanish Developmental Dyslexia

    Science.gov (United States)

    Jimenez, Juan E.; Hernandez-Valle, Isabel; Rodriguez, Cristina; Guzman, Remedios; Diaz, Alicia; Ortiz, Rosario

    2008-01-01

    The double-deficit hypothesis (DDH) of developmental dyslexia was investigated in seven to twelve year old Spanish children. It was observed that the double deficit (DD) group had the greatest difficulty with reading.

  1. The impact of a budget deficit on inflation in Zimbabwe

    OpenAIRE

    Makochekanwa, Albert

    2008-01-01

    The Zimbabwean economy is one of the many numbers of countries that has experienced a relatively high fiscal deficit for a prolonged period with the result of a high inflationary environment. This paper examines the deficit-inflation nexus in the Zimbabwean economy and establishes the causal link that runs from the budget deficit to the inflation rate using Johansen (1991, 1995) cointegration technique over the period 1980 – 2005. Due to massive monetization of the budget deficit, significant...

  2. Impact of Budget Deficit on Inflation in Zimbabwe

    OpenAIRE

    Albert Makochekanwa

    2011-01-01

    The Zimbabwean economy is one of the countries that once experienced a relatively high fiscal deficit for a prolonged period which resulted in a hyper inflationary environment. This paper examines the deficit-inflation nexus in the Zimbabwean economy and establishes the causal link that runs from the budget deficit to the inflation rate using Johansen (1991, 1995) cointegration technique over the period 1980 to 2005. Due to massive monetization of the budget deficit, significant inflationary ...

  3. Cognitive deficits in the remitted state of unipolar depressive disorder

    DEFF Research Database (Denmark)

    Hasselbalch, Bo Jacob; Knorr, Ulla Benedichte Søsted; Hasselbalch, Steen

    2012-01-01

    Patients with unipolar depressive disorder may present with cognitive deficits in the remitted state, and the aim of the present study was to investigate whether cognitive deficits within specific cognitive domains are present.......Patients with unipolar depressive disorder may present with cognitive deficits in the remitted state, and the aim of the present study was to investigate whether cognitive deficits within specific cognitive domains are present....

  4. Global Analysis of Ecosystem Evapotranspiration Response to Precipitation Deficits

    Science.gov (United States)

    He, Bin; Wang, Haiyan; Guo, Lanlan; Liu, Junjie

    2017-12-01

    Changes in ecosystem evapotranspiration (ET) due to precipitation deficits (PD) can relieve or aggravate soil moisture shortages, thus impacting drought severity. Previous findings have conflicted with regard to response of ET to PD. The present study relies on a global land ET synthesis data set (ETsyn) and observations from eddy-covariance towers (ETobs) to thoroughly examine the sensitivity of ET to PD, which is represented by the standardized precipitation index. There was a contrast in the response to PD between arid and humid ecosystems. ETsyn of arid ecosystems was typically reduced promptly in response to a reduction of precipitation, while ETsyn in humid ecosystems experienced a two-staged change: First, there was an enhancement, and then a reduction associated with persisting PD. Compared with ETsyn, ETobs suggests the occurrence of a more significant ET transition in response to PD. In arid ecosystems, ET typically negatively correlated with low PD, but this was limited by a large PD. Findings from this study are crucial for understanding the role of ET in drought evolution.

  5. Human brain lesion-deficit inference remapped.

    Science.gov (United States)

    Mah, Yee-Haur; Husain, Masud; Rees, Geraint; Nachev, Parashkev

    2014-09-01

    Our knowledge of the anatomical organization of the human brain in health and disease draws heavily on the study of patients with focal brain lesions. Historically the first method of mapping brain function, it is still potentially the most powerful, establishing the necessity of any putative neural substrate for a given function or deficit. Great inferential power, however, carries a crucial vulnerability: without stronger alternatives any consistent error cannot be easily detected. A hitherto unexamined source of such error is the structure of the high-dimensional distribution of patterns of focal damage, especially in ischaemic injury-the commonest aetiology in lesion-deficit studies-where the anatomy is naturally shaped by the architecture of the vascular tree. This distribution is so complex that analysis of lesion data sets of conventional size cannot illuminate its structure, leaving us in the dark about the presence or absence of such error. To examine this crucial question we assembled the largest known set of focal brain lesions (n = 581), derived from unselected patients with acute ischaemic injury (mean age = 62.3 years, standard deviation = 17.8, male:female ratio = 0.547), visualized with diffusion-weighted magnetic resonance imaging, and processed with validated automated lesion segmentation routines. High-dimensional analysis of this data revealed a hidden bias within the multivariate patterns of damage that will consistently distort lesion-deficit maps, displacing inferred critical regions from their true locations, in a manner opaque to replication. Quantifying the size of this mislocalization demonstrates that past lesion-deficit relationships estimated with conventional inferential methodology are likely to be significantly displaced, by a magnitude dependent on the unknown underlying lesion-deficit relationship itself. Past studies therefore cannot be retrospectively corrected, except by new knowledge that would render them redundant

  6. Perceived Cognitive Deficits, Emotional Distress and Disability following Whiplash Injury

    Directory of Open Access Journals (Sweden)

    Michael JL Sullivan

    2002-01-01

    Full Text Available OBJECTIVES: To describe the pattern of perceived cognitive deficits in patients with whiplash injury, to examine the relation between perceived cognitive deficits and disability, and to examine the determinants of perceived cognitive deficits in patients with whiplash injury.

  7. Greenhouse evaluation of deficit irrigation on the growth of tomato ...

    African Journals Online (AJOL)

    Deficit irrigation is considered to be an important approach for crop cultivation in dry regions where water resources are scarce. Deficit irrigation can be used also to decrease the level of infections by some moisturedependent plant pests and diseases such as root-knot nematode disease. Therefore, deficit irrigation at levels ...

  8. Word Processing in Dyslexics: An Automatic Decoding Deficit?

    Science.gov (United States)

    Yap, Regina; Van Der Leu, Aryan

    1993-01-01

    Compares dyslexic children with normal readers on measures of phonological decoding and automatic word processing. Finds that dyslexics have a deficit in automatic phonological decoding skills. Discusses results within the framework of the phonological deficit and the automatization deficit hypotheses. (RS)

  9. The Radiation Protection Act

    International Nuclear Information System (INIS)

    Persson, L.

    1989-01-01

    The new Radiation Protection Act (1988:220) entered into force in Sweden on July 1st, 1988. This book presents the Act as well as certain regulations connected to it. As previously, the main responsibility for public radiation protection will rest with one central radiation protection authority. According to the 1988 Act, the general obligations with regard to radiation protection will place a greater responsibility than in the past on persons carrying out activities involving radiation. Under the act, it is possible to adjust the licensing and supervisory procedures to the level of danger of the radiation source and the need for adequate competence, etc. The Act recognises standardised approval procedures combined with technical regulations for areas where the risks are well known. The Act contains several rules providing for more effective supervision. The supervising authority may in particular decide on the necessary regulations and prohibitions for each individual case. The possibilities of using penal provisions have been extended and a rule on the mandatory execution of orders has been introduced. The Ordinance on Radiation Protection (1988:293) designates the National Institute of Radiation Protection (SSI) as the central authority referred to in the Radiation Protection Act. The book also gives a historic review of radiation protection laws in Sweden, lists regulations issued by SSI and presents explanations of radiation effects and international norms in the area. (author)

  10. Reduction in language testing

    DEFF Research Database (Denmark)

    Dimova, Slobodanka; Jensen, Christian

    2013-01-01

    /video recorded speech samples and written reports produced by two experienced raters after testing. Our findings suggest that reduction or reduction-like pronunciation features are found in tested L2 speech, but whenever raters identify and comment on such reductions, they tend to assess reductions negatively......This study represents an initial exploration of raters' comments and actual realisations of form reductions in L2 test speech performances. Performances of three L2 speakers were selected as case studies and illustrations of how reductions are evaluated by the raters. The analysis is based on audio...

  11. The Energy Act 1983

    International Nuclear Information System (INIS)

    1983-01-01

    Part II of This Act came into force on 1 September 1983 and is concerned with nuclear installations. Its main purpose is to amend the Nuclear Installations Act 1965 to give effect to the provisions of two Protocols amending the Paris Convention on nuclear third party liability and the Brussels Convention Supplementary to the Paris Convention respectively. The principal effect of these modifications is to increase the sums available to meet claims for nuclear damage. The United Kingdom is a Party to both Conventions and the provisions of the 1983 Act will enable it to ratify the Protocols. (NEA) [fr

  12. Motivation deficits and use of alcohol and illicit drugs among individuals with schizophrenia.

    Science.gov (United States)

    Bahorik, Amber L; Greeno, Catherine G; Cochran, Gerald; Cornelius, Jack R; Eack, Shaun M

    2017-07-01

    This study examined the impact of substance use on intrinsic motivation and evaluated the association between intrinsic motivation and substance use recovery among individuals with schizophrenia. Alcohol and illicit drug use and intrinsic motivation were evaluated at baseline and 6-months for 1434 individuals with schizophrenia from the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) using self-rated substance use assessments and a derived motivation measure from the Heinrichs-Carpenter Quality of Life Scale. Results revealed patients had moderate motivation deficits overall and a considerable number were using alcohol or illicit drugs at baseline (n=576; 40.2%). Regression models at baseline showed patients with low levels of motivation had higher odds of substance use and those who were using substances had greater motivation deficits. At 6-months, substance using patients continued to demonstrate greater motivation deficits; however, those with high levels of motivation exhibited a greater reduction in their use of substances. Findings remained significant after adjusting for clinical confounds and were consistent across any substance, alcohol, and cannabis use. Our results emphasize concerns about substance use compounding motivation deficits in schizophrenia, and suggest that disentangling the motivation-substance use relationship in schizophrenia may facilitate efforts aimed at ameliorating these challenges and improving outcomes. Copyright © 2017 Elsevier Ireland Ltd. All rights reserved.

  13. Yield response of cotton, maize, soybean, sugar beet, sunflower and wheat to deficit irrigation

    International Nuclear Information System (INIS)

    Kirda, C.; Kanber, R.; Tulucu, K.

    1995-01-01

    Results of several field experiments on deficit irrigation programmes in Turkey are discussed. Deficit irrigation of sugar beet with water stress imposed (i e.,irrigation omitted)during ripening,stage saved nearly 22 % water, yet with no significant yield decrease. An experiment, conducted in Turkey Region, the European part of Turkey,and aimed at studying water production functions of sunflower(i e,yield vs water consumption), revealed that water stress imposed at either head forming or seed filling stags influence yield the least , and 40 % savings of irrigation water supply , compared with traditional practices in the region, can be achieved without significant yield reduction. Water stress imposed at vegetative and flowering stages of maize hindered the yield most significantly. The results showed that deficit irrigation can be a feasible option under limited supply of irrigation if stress occurs during yield formation stage. A four year field experiments aiming at developing deficit irrigation strategies for soybean showed that soybean was at the most sensitive to water stress during flowering and pod filling stages, and irrigation during these stages would ensure high yields. Results of experiments on cotton showed that irrigations omitted during yield formation stage did not significantly hinder the yield. Similarly wheat give good yield response if irrigated at booting,heading and milking stages, depending on w heather conditions. In areas where rainfall at planting is limited, supplementary irrigation during this period can ensure good establishment of wheat crop. 1 tab; 9 figs; 59 refs (Author)

  14. Olanzapine Reverses MK-801-Induced Cognitive Deficits and Region-Specific Alterations of NMDA Receptor Subunits

    Science.gov (United States)

    Liu, Xiao; Li, Jitao; Guo, Chunmei; Wang, Hongli; Sun, Yaxin; Wang, Han; Su, Yun-Ai; Li, Keqing; Si, Tianmei

    2018-01-01

    Cognitive dysfunction constitutes an essential component in schizophrenia for its early presence in the pathophysiology of the disease and close relatedness to life quality of patients. To develop effective treatment of cognitive deficits, it is important to understand their neurobiological causes and to identify potential therapeutic targets. In this study, adopting repeated MK-801 treatment as an animal model of schizophrenia, we investigated whether antipsychotic drugs, olanzapine and haloperidol, can reverse MK-801-induced cognitive deficits and how the reversal processes recruited proteins involved in glutamate neurotransmission in rat medial prefrontal cortex (mPFC) and hippocampus. We found that low-dose chronic MK-801 treatment impaired object-in-context recognition memory and reversal learning in the Morris water maze, leaving reference memory relatively unaffected, and that these cognitive deficits can be partially reversed by olanzapine, not haloperidol, treatment. At the molecular level, chronic MK-801 treatment resulted in the reduction of multiple N-methyl-D-aspartate (NMDA) receptor subunits in rat mPFC and olanzapine, not haloperidol, treatment restored the levels of GluN1 and phosphorylated GluN2B in this region. Taken together, MK-801-induced cognitive deficits may be associated with region-specific changes in NMDA receptor subunits and the reversal of specific NMDA receptor subunits may underlie the cognition-enhancing effects of olanzapine. PMID:29375333

  15. 75 FR 63703 - Privacy Act of 1974; Privacy Act Regulation

    Science.gov (United States)

    2010-10-18

    ... FEDERAL RESERVE SYSTEM 12 CFR Part 261a [Docket No. R-1313] Privacy Act of 1974; Privacy Act... implementing the Privacy Act of 1974 (Privacy Act). The primary changes concern the waiver of copying fees... records under the Privacy Act; the amendment of special procedures for the release of medical records to...

  16. Terminological and Definitional Problems of Deficit and Debt in the Polish and EU Law of Public Finance

    Directory of Open Access Journals (Sweden)

    Ewa Lotko

    2016-06-01

    Full Text Available In the Polish and the EU public finances law there are serious terminological difficulties concerning the deficit and the debt. They arise first from the terminological chaos in this field and second from the parallel application of the EU and the Polish methodology of calculating of deficit and debt. Thus, the paper aims to explain the terminological and definitional problems of deficit and debt in the public finances law using unobtrusive research consisting of the detailed analysis of the Polish and EU legislation. Although there is no doubt that it would be desirable to order the applied terms, in the current legal situation, it would be extremely difficult, as it would require the changes to the Constitution, laws, and modification of translations of UE acts. The solution to the problem, presenting additional advantages, could consist of full transition to the EU methodology by the renouncement from the Polish methodology.

  17. Traumatic brain injury: analysis of functional deficits and posthospital rehabilitation outcomes.

    Science.gov (United States)

    Lewis, Frank D; Horn, Gordon J

    2013-01-01

    admitted more than 1 year postinjury, t(78) = 8.05, p < .0001. Skill deficits interfering with reintegration into home and community are highly interrelated and should be treated with the understanding that progress in one area may be dependent on change in another area. Cognitive skills including memory, attention/ concentration, novel problem solving, and awareness of deficits were highly correlated with measures of overall functional outcome. Posthospital programs using a multidisciplinary treatment approach achieved significant reduction in disability from program admission to discharge. The benefits of these programs were realized even for the most chronically-impaired participants. 2013.

  18. Traumatic knee extension deficit (the locked knee)

    DEFF Research Database (Denmark)

    Helmark, I C; Neergaard, K; Krogsgaard, M R

    2007-01-01

    In the present study we investigated the validity of magnetic resonance imaging (MRI) and arthroscopy in knees with acute, traumatic extension deficit (the "locked knee"), and evaluated whether arthroscopy of knees with no mechanical pathology could be avoided by MRI evaluation. The study consisted...... of 50 patients who had an acute, traumatic extension deficit of the knee. All patients were submitted to MRI prior to arthroscopy. Following MRI and surgery, standardized forms were filled out, attempting to objectify the findings. The orthopaedic surgeon was not aware of the MRI result prior to surgery....... Evaluating MRI, all grade-3 meniscal lesions were considered able to cause a mechanical block as well as acute partial or total anterior cruciate ligament (ACL)-ruptures. ACL-ruptures with an old appearance were not considered able to cause locking. Assuming that arthroscopy was the gold standard...

  19. Flood Risk Assessment Based On Security Deficit Analysis

    Science.gov (United States)

    Beck, J.; Metzger, R.; Hingray, B.; Musy, A.

    degree of security deficit if the risk is unacceptable. Resulting risk maps showed that the risk to the majority of objects in the floodplain is acceptable. Unacceptable risk was identified though, so mitigation should be considered for the concerned objects. This methodology, if done for a large region (such as a large river basin), would be quite helpful to water- way managers to prioritize the mitigation and, furthermore, to estimate the impact of possible risk reduction measures.

  20. Common Cognitive Deficits in Children with Attention-Deficit/Hyperactivity Disorder and Autism: Working Memory and Visual-Motor Integration

    Science.gov (United States)

    Englund, Julia A.; Decker, Scott L.; Allen, Ryan A.; Roberts, Alycia M.

    2014-01-01

    Cognitive deficits in working memory (WM) are characteristic features of Attention-Deficit/Hyperactivity Disorder (ADHD) and autism. However, few studies have investigated cognitive deficits using a wide range of cognitive measures. We compared children with ADHD ("n" = 49) and autism ("n" = 33) with a demographically matched…

  1. The deficit mechanism of the Hungarian municipalities

    OpenAIRE

    Vasvári, Tamás

    2012-01-01

    The management of the Hungarian municipal sector has received special attention since the crisis in 2008 and interest in the sector increased further due to the changes in legislation in 2011. A great number of economy experts and speakers on behalf of the government or the municipalities provided further details on prevailing issues in the municipal sector, however, their assessment of the severity of these issues varied greatly. By describing the logical framework of the deficit mechanism t...

  2. Sensorimotor gating deficits in multiple system atrophy

    DEFF Research Database (Denmark)

    Zoetmulder, Marielle; Biernat, Heidi Bryde; Nikolic, Miki

    2014-01-01

    Prepulse inhibition (PPI) of the auditory blink reflex is a measure of sensorimotor gating, which reflects an organism's ability to filter out irrelevant sensory information. PPI has never been studied in patients with multiple system atrophy (MSA), although sensorimotor deficits are frequently a...... associated with synucleinopathies. We investigated whether alterations in PPI were more pronounced in MSA compared with Parkinson's disease (PD), idiopathic rapid eye movement sleep behavior disorder (iRBD) and healthy controls....

  3. ATTENTION DEFICIT HYPERACTIVITY DISORDER. A CLINICAL LECTURE

    OpenAIRE

    A. S. Kotov; M. N. Borisova; M. V. Panteleeva; Yu. V. Matyuk; A. V. Shatalin

    2015-01-01

    Attention deficit hyperactivity disorder (ADHD) is a serious problem to pediatric neurologists. The prevalence of ADHD in developed countries ranges from 1 to 20 %. ADHD is characterized by a triad of symptoms: inattention, hyperactivity, and impulsivity (the International Statistical Classification of Diseases, 10th revision, codes it as F90) and it is the most common conduct disorder in children. The etiology of ADHD remains disсutable to the present day; there are a few basic concepts of t...

  4. Evidence of female-specific glial deficits in the hippocampus in a mouse model of prenatal stress.

    LENUS (Irish Health Repository)

    Behan, Aine T

    2011-01-01

    Prenatal stress (PS) has been associated with an increased incidence of numerous neuropsychiatric disorders, including depression, anxiety, schizophrenia, and autism. To determine the effects of PS on hippocampal-dependent behaviour hippocampal morphology, we examined behavioural responses and hippocampal cytoarchitecture of a maternal restraint stress paradigm of PS in C57BL6 mice. Female offspring only showed a reduction in hippocampal glial count in the pyramidal layer following PS. Additionally, only PS females showed increased depressive-like behaviour with cognitive deficits predominantly in female offspring when compared to males. This data provides evidence for functional female-specific glial deficits within the hippocampus as a consequence of PS.

  5. Evidence of female-specific glial deficits in the hippocampus in a mouse model of prenatal stress.

    LENUS (Irish Health Repository)

    Behan, Aine T

    2012-02-01

    Prenatal stress (PS) has been associated with an increased incidence of numerous neuropsychiatric disorders, including depression, anxiety, schizophrenia, and autism. To determine the effects of PS on hippocampal-dependent behaviour hippocampal morphology, we examined behavioural responses and hippocampal cytoarchitecture of a maternal restraint stress paradigm of PS in C57BL6 mice. Female offspring only showed a reduction in hippocampal glial count in the pyramidal layer following PS. Additionally, only PS females showed increased depressive-like behaviour with cognitive deficits predominantly in female offspring when compared to males. This data provides evidence for functional female-specific glial deficits within the hippocampus as a consequence of PS.

  6. Abandoned Shipwreck Act

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data represents the extent of the Abandoned Shipwreck Act (ASA). The ASA allows states to manage a broad range of resources within submerged lands, including...

  7. Airway Clearance Techniques (ACTs)

    Medline Plus

    Full Text Available ... The Preserving Employee Wellness Programs Act Our Advocacy Work Advocacy ... the value of tapping into the expertise that only people with CF and their families have. We invite you to share insights to ...

  8. Energy Policy Act

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Energy Policy Act (EPA) addresses energy production in the United States, including: (1) energy efficiency; (2) renewable energy; (3) oil and gas; (4) coal; (5)...

  9. ACTS – SUCCESS STORY

    Indian Academy of Sciences (India)

    First page Back Continue Last page Overview Graphics. ACTS – SUCCESS STORY. Totally 103 experiments were conducted and the programme succeeded in the areas. Medicine; Education; Defence; Emergency Response; Maritime and Aeronautical Mobile Communications; Science and Astronomy.

  10. Airway Clearance Techniques (ACTs)

    Medline Plus

    Full Text Available ... There are different ways to clear your airways. Most are easy to do. Infants and toddlers will ... best ACT is the one that you are most likely to perform as part of your daily ...

  11. Airway Clearance Techniques (ACTs)

    Medline Plus

    Full Text Available ... to loosen mucus from airway walls. See how different airway clearance techniques work to help you clear the thick, sticky mucus ... Offer their tips for fitting ACTs into daily life Airway Clearance Techniques | Webcast ... Facebook Twitter ...

  12. Airway Clearance Techniques (ACTs)

    Medline Plus

    Full Text Available ... CF Community in Health Care Reform Milestones in Health Care Reform How Tax Reform Could Impact People With CF The Preserving Employee Wellness Programs Act Our Advocacy Work Advocacy Achievements ...

  13. Clean Water Act

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — These data represent geographic terms used within the Clean Water Act (CWA). The CWA establishes the basic structure for regulating the addition of pollutants...

  14. Airway Clearance Techniques (ACTs)

    Medline Plus

    Full Text Available ... toddlers will need help from a parent or caregiver. Older kids and adults can choose ACTs that ... into the smaller airways to attack bacteria. Choose What's Best for You Your respiratory therapist or another ...

  15. Airway Clearance Techniques (ACTs)

    Medline Plus

    Full Text Available ... that help thin and move the mucus, and antibiotics. Bronchodilators should be inhaled before you start ACTs. This medication helps to widen your airways (bronchi) by relaxing the ...

  16. Endangered Species Act

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The purpose of the Endangered Species Act (ESA) is to protect and recover imperiled species and the ecosystems upon which they depend. The U.S. Fish and Wildlife...

  17. Airway Clearance Techniques (ACTs)

    Medline Plus

    Full Text Available ... Reform Could Impact People With CF The Preserving Employee Wellness Programs Act Our Advocacy Work Advocacy Achievements ... on their own. Share Facebook Twitter Email More options Print Share Facebook Twitter Email Print Permalink All ...

  18. Airway Clearance Techniques (ACTs)

    Medline Plus

    Full Text Available ... 3-D Structure Consortium CFTR Folding Consortium Epithelial Stem Cell Consortium Mucociliary Clearance Consortium SUCCESS WITH THERAPIES RESEARCH ... ACTs involve coughing or huffing . Many of them use percussion (clapping) or vibration to loosen mucus from ...

  19. Airway Clearance Techniques (ACTs)

    Medline Plus

    Full Text Available ... today. ANNUAL FUND Become a Corporate Supporter Cause Marketing Make a Charitable Gift Our Corporate Supporters Workplace ... Clearance Airway Clearance Techniques (ACTs) There are different ways to clear your airways. Most are easy to ...

  20. Marine Pollution Prevention Act

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Marine Pollution Prevention Act of 2008 implements the International Convention for the Prevention of Pollution from Ships, including related Protocols (MARPOL)...