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Sample records for cycle validation experimentale

  1. Estudios Experimentales 2 Parte: Estudios Cuasi-Experimentales

    OpenAIRE

    Manterola, Carlos; Otzen, Tamara

    2015-01-01

    Los estudios experimentales, se caracterizan por la valoración del efecto de una o más intervenciones, habitualmente de forma comparativa con otra intervención, o un placebo; y el carácter prospectivo, de la recolección de datos y seguimiento. Agrupados bajo esta denominación, existe una diversidad de diseños, entre los que se encuentran los estudios cuasi-experimentales (ECE), que se caracterizan especialmente por la ausencia de asignación aleatoria. El objetivo de este manuscrito, es report...

  2. Estudios Experimentales 1 Parte: El Ensayo Clínico

    OpenAIRE

    Manterola, Carlos; Otzen, Tamara

    2015-01-01

    Los estudios experimentales, se caracterizan por la valoración del efecto de una o más intervenciones, habitualmente de forma comparativa con otra intervención, o un placebo; y el carácter prospectivo, de la recolección de los datos y el seguimiento de los grupos en estudio. Bajo la denominación de estudios experimentales, existe una diversidad de diseños, desde los ensayos clínicos (EC) y sus variantes, hasta los estudios cuasi-experimentales y los experientos naturales. El objetivo de este ...

  3. 40 CFR 1065.514 - Cycle-validation criteria for operation over specified duty cycles.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Cycle-validation criteria for operation over specified duty cycles. 1065.514 Section 1065.514 Protection of Environment ENVIRONMENTAL... Over Specified Duty Cycles § 1065.514 Cycle-validation criteria for operation over specified duty...

  4. Validity of Wearable Activity Monitors during Cycling and Resistance Exercise.

    Science.gov (United States)

    Boudreaux, Benjamin D; Hebert, Edward P; Hollander, Daniel B; Williams, Brian M; Cormier, Corinne L; Naquin, Mildred R; Gillan, Wynn W; Gusew, Emily E; Kraemer, Robert R

    2018-03-01

    The use of wearable activity monitors has seen rapid growth; however, the mode and intensity of exercise could affect the validity of heart rate (HR) and caloric (energy) expenditure (EE) readings. There is a lack of data regarding the validity of wearable activity monitors during graded cycling regimen and a standard resistance exercise. The present study determined the validity of eight monitors for HR compared with an ECG and seven monitors for EE compared with a metabolic analyzer during graded cycling and resistance exercise. Fifty subjects (28 women, 22 men) completed separate trials of graded cycling and three sets of four resistance exercises at a 10-repetition-maximum load. Monitors included the following: Apple Watch Series 2, Fitbit Blaze, Fitbit Charge 2, Polar H7, Polar A360, Garmin Vivosmart HR, TomTom Touch, and Bose SoundSport Pulse (BSP) headphones. HR was recorded after each cycling intensity and after each resistance exercise set. EE was recorded after both protocols. Validity was established as having a mean absolute percent error (MAPE) value of ≤10%. The Polar H7 and BSP were valid during both exercise modes (cycling: MAPE = 6.87%, R = 0.79; resistance exercise: MAPE = 6.31%, R = 0.83). During cycling, the Apple Watch Series 2 revealed the greatest HR validity (MAPE = 4.14%, R = 0.80). The BSP revealed the greatest HR accuracy during resistance exercise (MAPE = 6.24%, R = 0.86). Across all devices, as exercise intensity increased, there was greater underestimation of HR. No device was valid for EE during cycling or resistance exercise. HR from wearable devices differed at different exercise intensities; EE estimates from wearable devices were inaccurate. Wearable devices are not medical devices, and users should be cautious when using these devices for monitoring physiological responses to exercise.

  5. Modelisation numerique et validation experimentale d'un systeme de protection contre le givre par elements piezoelectriques

    Science.gov (United States)

    Harvey, Derek

    Le degivrage au moyen d'actuateurs piezoelectriques est considere comme une avenue prometteuse pour le developpement de systemes a faible consommation d'energie applicables aux helicopteres legers. Ce type de systeme excite des frequences de resonances d'une structure pour produire des deformations suffisantes pour rompre l'adherence de la glace. Par contre, la conception de tel systeme demeure generalement mal comprise. Ce projet de maitrise etudie l'utilisation de methodes numeriques pour assister la conception des systemes de protection contre le givre a base d'elements piezoelectriques. La methodologie retenue pour ce projet a ete de modeliser differentes structures simples et de simuler l'excitation harmonique des frequences de resonance au moyen d'actuateurs piezoelectriques. Le calcul des frequences de resonances ainsi que la simulation de leur excitation a ensuite ete validee a l'aide de montages experimentaux. La procedure a ete realisee pour une poutre en porte-a-faux et pour une plaque plane a l'aide du logiciel de calcul par elements finis, Abaqus. De plus, le modele de la plaque plane a ete utilise afin de realiser une etude parametrique portant sur le positionnement des actuateurs, l'effet de la rigidite ainsi que de l'epaisseur de la plaque. Finalement, la plaque plane a ete degivree en chambre climatique. Des cas de degivrage ont ete simules numeriquement afin d'etudier la possibilite d'utiliser un critere base sur la deformation pour predire le succes du systeme. La validation experimentale a confirme la capacite du logiciel a calculer precisement a la fois les frequences et les modes de resonance d'une structure et a simuler leur excitation par des actuateurs piezoelectriques. L'etude revele que la definition de l'amortissement dans le modele numerique est essentiel pour l'obtention de resultats precis. Les resultats de l'etude parametrique ont demontre l'importance de minimiser l'epaisseur et la rigidite afin de reduire la valeur des frequences

  6. Diseños cuasi-experimentales y longitudinales

    OpenAIRE

    Bono Cabré, Roser

    2012-01-01

    Los diseños cuasi-experimentales son estrategias que, guiadas por unos objetivos, pretenden examinar las relaciones existentes entre una o más variables independientes y la variable dependiente o de respuesta. En el diseño cuasi-experimental, dado que los grupos son naturales, la equivalencia inicial se garantiza mediante la selección de grupos comparables o a través de alguna técnica de ajuste estadístico. Con los diseños longitudinales el investigador incorpora, dentro de la estructura del ...

  7. Validation and application of a physics database for fast reactor fuel cycle analysis

    International Nuclear Information System (INIS)

    McKnight, R.D.; Stillman, J.A.; Toppel, B.J.; Khalil, H.S.

    1994-01-01

    An effort has been made to automate the execution of fast reactor fuel cycle analysis, using EBR-II as a demonstration vehicle, and to validate the analysis results for application to the IFR closed fuel cycle demonstration at EBR-II and its fuel cycle facility. This effort has included: (1) the application of the standard ANL depletion codes to perform core-follow analyses for an extensive series of EBR-II runs, (2) incorporation of the EBR-II data into a physics database, (3) development and verification of software to update, maintain and verify the database files, (4) development and validation of fuel cycle models and methodology, (5) development and verification of software which utilizes this physics database to automate the application of the ANL depletion codes, methods and models to perform the core-follow analysis, and (6) validation studies of the ANL depletion codes and of their application in support of anticipated near-term operations in EBR-II and the Fuel Cycle Facility. Results of the validation tests indicate the physics database and associated analysis codes and procedures are adequate to predict required quantities in support of early phases of FCF operations

  8. El proceso enseñanza-aprendizaje de las Ciencias experimentales en una comunidad de aprendizaje

    OpenAIRE

    Ortega Quevedo, Vanessa

    2016-01-01

    La finalidad de este estudio es analizar el proceso de enseñanza-aprendizaje de las Ciencias Experimentales en una comunidad de aprendizaje. Para ello, se ha realizado una pequeña investigación sobre cómo profesores de un centro que ostenta el cargo de Comunidad de Aprendizaje trabajan las ciencias. Además, diseñan y llevan a la práctica una intervención que fusiona los modelos didácticos más usuales en la enseñanza de las Ciencias Experimentales, con la concepción comunicativa de la enseñanz...

  9. Experimental validation of calculated capture rate for nucleus involved in fuel cycle; Validation experimentale du calcul du taux de capture des noyaux intervenant dans le cycle du combustible

    Energy Technology Data Exchange (ETDEWEB)

    Benslimane-Bouland, A

    1997-09-01

    The framework of this study was the evaluation of the nuclear data requirements for Actinides and Fission Products applied to current nuclear reactors as well as future applications. This last item includes extended irradiation campaigns, 100 % Mixed Oxide fuel, transmutation or even incineration. The first part of this study presents different types of integral measurements which are available for capture rate measurements, as well as the methods used for reactor core calculation route design and nuclear data library validation. The second section concerns the analysis of three specific irradiation experiments. The results have shown the extent of the current knowledge on nuclear data as well as the associated uncertainties. The third and last section shows both the coherency between all the results, and the statistical method applied for nuclear data library adjustment. A relevant application of this method has demonstrated that only specifically chosen integral experiments can be of use for the validation of nuclear data libraries. The conclusion is reached that even if co-ordinated efforts between reactor and nuclear physicists have made possible a huge improvement in the knowledge of capture cross sections of the main nuclei such as uranium and plutonium, some improvements are currently necessary for the minor actinides (Np, Am and Cm). Both integral and differential measurements are recommended to improve the knowledge of minor actinide cross sections. As far as integral experiments are concerned, a set of criteria to be followed during the experimental conception have been defined in order to both reduce the number of required calculation approximations, and to increase as much as possible the maximum amount of extracted information. (author)

  10. Validation of a mathematical model of the bovine estrous cycle for cows with different estrous cycle characteristics.

    Science.gov (United States)

    Boer, H M T; Butler, S T; Stötzel, C; Te Pas, M F W; Veerkamp, R F; Woelders, H

    2017-11-01

    A recently developed mechanistic mathematical model of the bovine estrous cycle was parameterized to fit empirical data sets collected during one estrous cycle of 31 individual cows, with the main objective to further validate the model. The a priori criteria for validation were (1) the resulting model can simulate the measured data correctly (i.e. goodness of fit), and (2) this is achieved without needing extreme, probably non-physiological parameter values. We used a least squares optimization procedure to identify parameter configurations for the mathematical model to fit the empirical in vivo measurements of follicle and corpus luteum sizes, and the plasma concentrations of progesterone, estradiol, FSH and LH for each cow. The model was capable of accommodating normal variation in estrous cycle characteristics of individual cows. With the parameter sets estimated for the individual cows, the model behavior changed for 21 cows, with improved fit of the simulated output curves for 18 of these 21 cows. Moreover, the number of follicular waves was predicted correctly for 18 of the 25 two-wave and three-wave cows, without extreme parameter value changes. Estimation of specific parameters confirmed results of previous model simulations indicating that parameters involved in luteolytic signaling are very important for regulation of general estrous cycle characteristics, and are likely responsible for differences in estrous cycle characteristics between cows.

  11. Ciencias Experimentales en el aula de Educación Infantil

    OpenAIRE

    Zamalloa Echevarría, Teresa

    2013-01-01

    Duración (en horas): Más de 50 horas, Destinatario: Estudiante Mediante la metodología de ABP el alumnado de tercer curso del grado de Educación infantil elaborará propuestas didácticas en grupos para el estudio de los contenidos de ciencias experimentales empleando diferentes estrategias y recursos didácticos para la enseñanza/aprendizaje del medio físico y natural en Educación Infantil.

  12. Development and validation of a partial life-cycle test with Potamopyrgus antipodarum

    DEFF Research Database (Denmark)

    Geiss, Cornelia; Holbech, Henrik; Kinnberg, Karin Lund

    endpoints. The present study aims to develop and validate the partial life-cycle test on the reproduction of P. antipodarum. Here, results from two pre-validation studies of the reproduction test with the chemicals tributyltin (TBT) with nominal concentrations of 10 - 400 ng TBT-Sn/L and cadmium...

  13. Reliability and validity of four alternative definitions of rapid-cycling bipolar disorder.

    Science.gov (United States)

    Maj, M; Pirozzi, R; Formicola, A M; Tortorella, A

    1999-09-01

    This study tested the reliability and validity of four definitions of rapid cycling. Two trained psychiatrists, using the Schedule for Affective Disorders and Schizophrenia, independently assessed 210 patients with bipolar disorder. They checked whether each patient met four definitions of rapid cycling: one consistent with DSM-IV criteria, one waiving criteria for duration of affective episodes, one waiving such criteria and requiring at least one switch from mania to depression or vice versa during the reference year, and one waiving duration criteria and requiring at least 8 weeks of fully symptomatic affective illness during the reference year. The interrater reliability was calculated by Cohen's kappa statistic. Patients who met each definition according to both psychiatrists were compared to those who did not meet any definition (nonrapid-cycling group) on demographic and clinical variables. All patients were followed up for 1 year. Kappa values were 0.93, 0.73, 0.75, and 0.80, respectively, for the four definitions of rapid cycling. The groups meeting the second and third definitions included significantly more female and bipolar II patients than did the nonrapid-cycling group. Those two groups also had the lowest proportion of patients with a favorable lithium prophylaxis outcome and the highest stability of the rapid-cycling pattern on follow-up. The four groups of rapid-cycling patients did not differ significantly among themselves on any of the assessed variables. The expression "rapid cycling" encompasses a spectrum of conditions. The DSM-IV definition, although quite reliable, covers only part of this spectrum, and the conditions that are excluded are very typical in terms of key validators and are relatively stable over time.

  14. Development and Validation of A Nuclear Fuel Cycle Analysis Tool: A FUTURE Code

    Energy Technology Data Exchange (ETDEWEB)

    Kim, S. K.; Ko, W. I. [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Lee, Yoon Hee [Korea Advanced Institute of Science and Technology, Daejeon (Korea, Republic of)

    2013-10-15

    This paper presents the development and validation methods of the FUTURE (FUel cycle analysis Tool for nUcleaR Energy) code, which was developed for a dynamic material flow evaluation and economic analysis of the nuclear fuel cycle. This code enables an evaluation of a nuclear material flow and its economy for diverse nuclear fuel cycles based on a predictable scenario. The most notable virtue of this FUTURE code, which was developed using C and MICROSOFT SQL DBMS, is that a program user can design a nuclear fuel cycle process easily using a standard process on the canvas screen through a drag-and-drop method. From the user's point of view, this code is very easy to use thanks to its high flexibility. In addition, the new code also enables the maintenance of data integrity by constructing a database environment of the results of the nuclear fuel cycle analyses.

  15. Validation of different instruments for caffeine measurement among premenopausal women in the BioCycle study.

    Science.gov (United States)

    Schliep, Karen C; Schisterman, Enrique F; Mumford, Sunni L; Perkins, Neil J; Ye, Aijun; Pollack, Anna Z; Zhang, Cuilin; Porucznik, Christina A; VanDerslice, James A; Stanford, Joseph B; Wactawski-Wende, Jean

    2013-04-01

    Effects of caffeine on women's health are inconclusive, in part because of inadequate exposure assessment. In this study we determined 1) validity of a food frequency questionnaire compared with multiple 24-hour dietary recalls (24HDRs) for measuring monthly caffeine and caffeinated beverage intakes; and 2) validity of the 24HDR compared with the prior day's diary record for measuring daily caffeinated coffee intake. BioCycle Study (2005-2007) participants, women (n = 259) aged 18-44 years from western New York State, were followed for 2 menstrual cycles. Participants completed a food frequency questionnaire at the end of each cycle, four 24HDRs per cycle, and daily diaries. Caffeine intakes reported for the food frequency questionnaires were greater than those reported for the 24HDRs (mean = 114.1 vs. 92.6mg/day, P = 0.01) but showed high correlation (r = 0.73, P cups/day, P cup = 237 mL). Although caffeine and coffee exposures were highly correlated, absolute intakes differed significantly between measurement tools. These results highlight the importance of considering potential misclassification of caffeine exposure.

  16. Validity And Reliability Of The Stages Cycling Power Meter.

    Science.gov (United States)

    Granier, Cyril; Hausswirth, Christophe; Dorel, Sylvain; Yann, Le Meur

    2017-09-06

    This study aimed to determine the validity and the reliability of the Stages power meter crank system (Boulder, United States) during several laboratory cycling tasks. Eleven trained participants completed laboratory cycling trials on an indoor cycle fitted with SRM Professional and Stages systems. The trials consisted of an incremental test at 100W, 200W, 300W, 400W and four 7s sprints. The level of pedaling asymmetry was determined for each cycling intensity during a similar protocol completed on a Lode Excalibur Sport ergometer. The reliability of Stages and SRM power meters was compared by repeating the incremental test during a test-retest protocol on a Cyclus 2 ergometer. Over power ranges of 100-1250W the Stages system produced trivial to small differences compared to the SRM (standardized typical error values of 0.06, 0.24 and 0.08 for the incremental, sprint and combined trials, respectively). A large correlation was reported between the difference in power output (PO) between the two systems and the level of pedaling asymmetry (r=0.58, p system according to the level of pedaling asymmetry provided only marginal improvements in PO measures. The reliability of the Stages power meter at the sub-maximal intensities was similar to the SRM Professional model (coefficient of variation: 2.1 and 1.3% for Stages and SRM, respectively). The Stages system is a suitable device for PO measurements, except when a typical error of measurement power ranges of 100-1250W is expected.

  17. DEVELOPMENT AND VALIDATION OF A NUCLEAR FUEL CYCLE ANALYSIS TOOL: A FUTURE CODE

    Directory of Open Access Journals (Sweden)

    S.K. KIM

    2013-10-01

    Full Text Available This paper presents the development and validation methods of the FUTURE (FUel cycle analysis Tool for nUcleaR Energy code, which was developed for a dynamic material flow evaluation and economic analysis of the nuclear fuel cycle. This code enables an evaluation of a nuclear material flow and its economy for diverse nuclear fuel cycles based on a predictable scenario. The most notable virtue of this FUTURE code, which was developed using C# and MICROSOFT SQL DBMS, is that a program user can design a nuclear fuel cycle process easily using a standard process on the canvas screen through a drag-and-drop method. From the user's point of view, this code is very easy to use thanks to its high flexibility. In addition, the new code also enables the maintenance of data integrity by constructing a database environment of the results of the nuclear fuel cycle analyses.

  18. Assessing the environmental characteristics of cycling routes to school: a study on the reliability and validity of a Google Street View-based audit.

    Science.gov (United States)

    Vanwolleghem, Griet; Van Dyck, Delfien; Ducheyne, Fabian; De Bourdeaudhuij, Ilse; Cardon, Greet

    2014-06-10

    Google Street View provides a valuable and efficient alternative to observe the physical environment compared to on-site fieldwork. However, studies on the use, reliability and validity of Google Street View in a cycling-to-school context are lacking. We aimed to study the intra-, inter-rater reliability and criterion validity of EGA-Cycling (Environmental Google Street View Based Audit - Cycling to school), a newly developed audit using Google Street View to assess the physical environment along cycling routes to school. Parents (n = 52) of 11-to-12-year old Flemish children, who mostly cycled to school, completed a questionnaire and identified their child's cycling route to school on a street map. Fifty cycling routes of 11-to-12-year olds were identified and physical environmental characteristics along the identified routes were rated with EGA-Cycling (5 subscales; 37 items), based on Google Street View. To assess reliability, two researchers performed the audit. Criterion validity of the audit was examined by comparing the ratings based on Google Street View with ratings through on-site assessments. Intra-rater reliability was high (kappa range 0.47-1.00). Large variations in the inter-rater reliability (kappa range -0.03-1.00) and criterion validity scores (kappa range -0.06-1.00) were reported, with acceptable inter-rater reliability values for 43% of all items and acceptable criterion validity for 54% of all items. EGA-Cycling can be used to assess physical environmental characteristics along cycling routes to school. However, to assess the micro-environment specifically related to cycling, on-site assessments have to be added.

  19. The reliability and validity of fatigue measures during short-duration maximal-intensity intermittent cycling.

    Science.gov (United States)

    Glaister, Mark; Stone, Michael H; Stewart, Andrew M; Hughes, Michael; Moir, Gavin L

    2004-08-01

    The purpose of the present study was to assess the reliability and validity of fatigue measures, as derived from 4 separate formulae, during tests of repeat sprint ability. On separate days over a 3-week period, 2 groups of 7 recreationally active men completed 6 trials of 1 of 2 maximal (20 x 5 seconds) intermittent cycling tests with contrasting recovery periods (10 or 30 seconds). All trials were conducted on a friction-braked cycle ergometer, and fatigue scores were derived from measures of mean power output for each sprint. Apart from formula 1, which calculated fatigue from the percentage difference in mean power output between the first and last sprint, all remaining formulae produced fatigue scores that showed a reasonably good level of test-retest reliability in both intermittent test protocols (intraclass correlation range: 0.78-0.86; 95% likely range of true values: 0.54-0.97). Although between-protocol differences in the magnitude of the fatigue scores suggested good construct validity, within-protocol differences highlighted limitations with each formula. Overall, the results support the use of the percentage decrement score as the most valid and reliable measure of fatigue during brief maximal intermittent work.

  20. Integration and validation testing for PhEDEx, DBS and DAS with the PhEDEx LifeCycle agent

    International Nuclear Information System (INIS)

    Boeser, C; Chwalek, T; Giffels, M; Kuznetsov, V; Wildish, T

    2014-01-01

    The ever-increasing amount of data handled by the CMS dataflow and workflow management tools poses new challenges for cross-validation among different systems within CMS experiment at LHC. To approach this problem we developed an integration test suite based on the LifeCycle agent, a tool originally conceived for stress-testing new releases of PhEDEx, the CMS data-placement tool. The LifeCycle agent provides a framework for customising the test workflow in arbitrary ways, and can scale to levels of activity well beyond those seen in normal running. This means we can run realistic performance tests at scales not likely to be seen by the experiment for some years, or with custom topologies to examine particular situations that may cause concern some time in the future. The LifeCycle agent has recently been enhanced to become a general purpose integration and validation testing tool for major CMS services. It allows cross-system integration tests of all three components to be performed in controlled environments, without interfering with production services. In this paper we discuss the design and implementation of the LifeCycle agent. We describe how it is used for small-scale debugging and validation tests, and how we extend that to large-scale tests of whole groups of sub-systems. We show how the LifeCycle agent can emulate the action of operators, physicists, or software agents external to the system under test, and how it can be scaled to large and complex systems.

  1. Integration and validation testing for PhEDEx, DBS and DAS with the PhEDEx LifeCycle agent

    Science.gov (United States)

    Boeser, C.; Chwalek, T.; Giffels, M.; Kuznetsov, V.; Wildish, T.

    2014-06-01

    The ever-increasing amount of data handled by the CMS dataflow and workflow management tools poses new challenges for cross-validation among different systems within CMS experiment at LHC. To approach this problem we developed an integration test suite based on the LifeCycle agent, a tool originally conceived for stress-testing new releases of PhEDEx, the CMS data-placement tool. The LifeCycle agent provides a framework for customising the test workflow in arbitrary ways, and can scale to levels of activity well beyond those seen in normal running. This means we can run realistic performance tests at scales not likely to be seen by the experiment for some years, or with custom topologies to examine particular situations that may cause concern some time in the future. The LifeCycle agent has recently been enhanced to become a general purpose integration and validation testing tool for major CMS services. It allows cross-system integration tests of all three components to be performed in controlled environments, without interfering with production services. In this paper we discuss the design and implementation of the LifeCycle agent. We describe how it is used for small-scale debugging and validation tests, and how we extend that to large-scale tests of whole groups of sub-systems. We show how the LifeCycle agent can emulate the action of operators, physicists, or software agents external to the system under test, and how it can be scaled to large and complex systems.

  2. The turbulent viscosity models and their experimental validation; Les modeles de viscosite turbulente et leur validation experimentale

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-31

    This workshop on turbulent viscosity models and on their experimental validation was organized by the `convection` section of the French society of thermal engineers. From the 9 papers presented during this workshop, 8 deal with the modeling of turbulent flows inside combustion chambers, turbo-machineries or in other energy-related applications, and have been selected for ETDE. (J.S.)

  3. Integration and validation testing for PhEDEx, DBS and DAS with the PhEDEx LifeCycle agent

    CERN Document Server

    Wildish, Anthony

    2013-01-01

    The ever-increasing amount of data handled by the CMS dataflow and workflow management tools poses new challenges for cross-validation among different systems within CMS experiment at LHC. To approach this problem we developed an integration test suite based on the LifeCycle agent, a tool originally conceived for stress-testing new releases of PhEDEx, the CMS data-placement tool. The LifeCycle agent provides a framework for customising the test workflow in arbitrary ways, and can scale to levels of activity well beyond those seen in normal running. This means we can run realistic performance tests at scales not likely to be seen by the experiment for some years, or with custom topologies to examine particular situations that may cause concern some time in the future.The LifeCycle agent has recently been enhanced to become a general purpose integration and validation testing tool for major CMS services (PhEDEx, DBS, DAS). It allows cross-system integration tests of all three components to be performed in contr...

  4. Mesures experimentales de l'impact des revetements hydrophobeset superhydrophobes sur la trainee et la portance d'un profil aerodynamique propre et glace

    Science.gov (United States)

    Villeneuve, Eric

    Ce projet, realise a la demande du Laboratoire International des Materiaux Antigivre, a pour but de mesurer et definir experimentalement l'impact de revetements hydrophobes sur les coefficients de trainee et de portance d'un profil NACA 0012. Pour ce faire, la balance aerodynamique du LIMA devait tout d'abord etre amelioree afin d'offrir une sensibilite suffisante pour realiser le projet. Plusieurs ameliorations ont ete faites, comme le changement des cellules de charge, la diminution du nombre de cellules de charge, le changement du cadre de la balance, etc. Une fois ces ameliorations terminees, la reproductibilite, l'exactitude et la sensibilite ont ete valides afin de s'assurer de la fiabilite des resultats offerts par la balance. Pour les angles d'attaque etudies avec les revetements, soient -6° et 0°, la balance a une reproductibilite de +/-2,06% a 360 000 de nombre de Reynolds. Pour valider la sensibilite, des essais a -6° et 0° d'angle d'attaque et des nombres de Reynolds de 360 000 et 500 000 ont ete faits avec des papiers sables. Les resultats de ces essais ont permis de, tracer des courbes de tendances du coefficient de trainee du NACA 0012 en fonction de la rugosite de surface et d'etablir la valeur de la sensibilite de la balance a +/-8 mu m. Cinq revetements populaires ont ete choisis pour l'experimentation, soient le Wearlon, le Staclean, le Hirec, le Phasebreak ainsi que le Nusil. Les revetements sont soumis aux memes conditions experimentales que les papiers sables, et une rugosite equivalente est trouvee par extrapolation des resultats. Cependant, les rugosites equivalentes de surfaces different entre -6° et 0°. Les essais avec le Staclean et le Hirec donnent des coefficients de trainee equivalent a ceux avec l'aluminium, alors que le Wearlon, le Nusil et le Phasebreak donnent une augmentation du coefficient de trainee de 13%, 17% et 25% respectivement par rapport a l'aluminium. Pour les coefficients de portance, la balance ne detecte pas l

  5. El AMMI y cluster en la selección de los mejores híbridos experimentales de maíz

    Directory of Open Access Journals (Sweden)

    Guillermo Casta\\u00F1\\u00F3n

    2000-01-01

    Full Text Available El AMMI y Cluster en la selección de los mejores híbridos experimentales de maiz. En un experimento de maíz repetido en cuatro ambientes, se aplicó el análisis de efectos principales aditivos e interacción multiplicativa (AMMI y el de taxonomía numérica o cluster, para estudiar si la estabilidad del rendimiento de grano (RG de los híbridos ensayados se asociaba con el agrupamiento de los híbridos hecho por el cluster. Las variables que tuvieron más peso en el agrupamiento fueron el RG, altura de la planta (AP,altura de mazorca ( AM y mazorca por planta (PRO, principalmente. De lo encontrado en este trabajo se puede establecer que el AMMI es efectivo en la estimación de la estabilidad de los híbridos experimentales evaluados y que junto con el cluster, pueden ser dos herramientas útiles para hacer una buena selección de material experimental con mayores posibilidades de éxito

  6. Validation of the CATHARE2 code against experimental data from Brayton-cycle plants

    International Nuclear Information System (INIS)

    Bentivoglio, Fabrice; Tauveron, Nicolas; Geffraye, Genevieve; Gentner, Herve

    2008-01-01

    In recent years the Commissariat a l'Energie Atomique (CEA) has commissioned a wide range of feasibility studies of future-advanced nuclear reactors, in particular gas-cooled reactors (GCR). The thermohydraulic behaviour of these systems is a key issue for, among other things, the design of the core, the assessment of thermal stresses, and the design of decay heat removal systems. These studies therefore require efficient and reliable simulation tools capable of modelling the whole reactor, including the core, the core vessel, piping, heat exchangers and turbo-machinery. CATHARE2 is a thermal-hydraulic 1D reference safety code developed and extensively validated for the French pressurized water reactors. It has been recently adapted to deal also with gas-cooled reactor applications. In order to validate CATHARE2 for these new applications, CEA has initiated an ambitious long-term experimental program. The foreseen experimental facilities range from small-scale loops for physical correlations, to component technology and system demonstration loops. In the short-term perspective, CATHARE2 is being validated against existing experimental data. And in particular from the German power plants Oberhausen I and II. These facilities have both been operated by the German utility Energie Versorgung Oberhausen (E.V.O.) and their power conversion systems resemble to the high-temperature reactor concepts: Oberhausen I is a 13.75-MWe Brayton-cycle air turbine plant, and Oberhausen II is a 50-MWe Brayton-cycle helium turbine plant. The paper presents these two plants, the adopted CATHARE2 modelling and a comparison between experimental data and code results for both steady state and transient cases

  7. Respuesta hidrológica en medios semiáridos: Las cuencas experimentales de la Sierra de El Picarcho, Murcia (España)

    OpenAIRE

    Castillo Sánchez, Victor Manuel; Gómez-Plaza, A.; Martínez-Mena García, M. Dolores; Albaladejo Montoro, Juan

    2000-01-01

    [ES] Las cuencas experimentales de la Sierra del Picarcho se establecieron en 1997 para estudiar los factores que controlan la generación de escorrentía en distintas escalas de trabajo, analizar la variabilidad de estos factores y desarrollar modelos hidrológicos de simulación adaptados a estos ambientes.

  8. The process of processing: exploring the validity of Neisser's perceptual cycle model with accounts from critical decision-making in the cockpit.

    Science.gov (United States)

    Plant, Katherine L; Stanton, Neville A

    2015-01-01

    The perceptual cycle model (PCM) has been widely applied in ergonomics research in domains including road, rail and aviation. The PCM assumes that information processing occurs in a cyclical manner drawing on top-down and bottom-up influences to produce perceptual exploration and actions. However, the validity of the model has not been addressed. This paper explores the construct validity of the PCM in the context of aeronautical decision-making. The critical decision method was used to interview 20 helicopter pilots about critical decision-making. The data were qualitatively analysed using an established coding scheme, and composite PCMs for incident phases were constructed. It was found that the PCM provided a mutually exclusive and exhaustive classification of the information-processing cycles for dealing with critical incidents. However, a counter-cycle was also discovered which has been attributed to skill-based behaviour, characteristic of experts. The practical applications and future research questions are discussed. Practitioner Summary: This paper explores whether information processing, when dealing with critical incidents, occurs in the manner anticipated by the perceptual cycle model. In addition to the traditional processing cycle, a reciprocal counter-cycle was found. This research can be utilised by those who use the model as an accident analysis framework.

  9. Etude theorique et experimentale des evaporateurs de dioxyde de carbone operant dans des conditions de givrage

    Science.gov (United States)

    Bendaoud, Adlane Larbi

    . Dans la partie theorique, un modele traitant les aspects thermique, hydrodynamique et massique a ete elabore. Sur la base de ce modele a ete ecrit un programme informatique en langage FORTRAN 6.6. Il est base sur la discretisation du serpentin en volumes de controle, est entierement automatise et peut traiter des echangeurs de chaleur avec des circuits de refrigerant complexes pouvant avoir des entrees et sorties multiples ainsi que des bifurcations. La presence simultanee des trois phases thermodynamiques du refrigerant (liquide sous refroidi, fluide sature, vapeur surchauffee) dans le serpentin est aussi prise en charge. Le modele a ete valide pour un fonctionnement avec et sans formation de givre en utilisant des donnees experimentales disponibles dans la litterature et celles obtenues sur le banc d'essai de CanmetENERGIE. Celui-ci a ete mis a jour pour les besoins de la presente recherche et pour cela, un systeme de surchauffe et d'injection de la vapeur d'eau dans une enceinte a tres basse temperature a ete dimensionne, fabrique et installe. Un dispositif de visualisation de la formation de givre, ainsi qu'un equipement de mesure de la temperature, de la pression et de l'humidite relative de l'air ont aussi ete ajoutes. Une fois le modele valide, des simulations numeriques sur le serpentin avec et sans formation de givre ont ete effectuees. Un premier cas de base a servi comme reference pour d'autres cas pour lesquels une etude parametrique sur la geometrie et le fonctionnement a ete menee. Il a ete montre par rapport au cas de base que : 1. la diminution de la densite des ailettes sur des rangees specifiques du serpentin donne une surface minimale (Amin) plus grande, retardant ainsi l'obstruction totale du serpentin par le givre et permet donc un temps de fonctionnement plus grand et une frequence de degivrage plus faible. 2. une bonne configuration de circuit de refrigerant augmente le temps de fonctionnement du serpentin de 200 % et delivre une puissance

  10. Vehicle modeling and duty cycle analysis to validate technology feasibility

    Energy Technology Data Exchange (ETDEWEB)

    Castonguay, S. [National Centre for Advanced Transportation, Saint-Jerome, PQ (Canada)

    2010-07-01

    The National Centre for Advanced Transportation (CNTA) is a non-profit organization with a board consisting of representatives from the transportation industry, public service and public transit organizations, research and teaching institutions, and from municipal and economic development organizations. The objectives of the CNTA are to accelerate the introduction of electric and hybrid vehicles; act as a catalyst in projects; assist in increasing Canadian technology assets; initiate and support electric vehicle conversion projects; increase Canadian business for electric vehicles, hybrid vehicles, and plug-in electric vehicles; and provide a cost-effective solution and aggressive payback for road/off-road vehicles. This presentation provided an overview of the objectives and services of the CNTA. It discussed various road and off-road vehicles, duty cycle and technology of electric vehicles. Specific topics related to the technology were discussed, including configuration; controls and interface; efficiency maps; models and simulation; validation; and support. figs.

  11. Numerical simulation and experimental validation of internal heat exchanger influence on CO{sub 2} trans-critical cycle performance

    Energy Technology Data Exchange (ETDEWEB)

    Rigola, Joaquim; Ablanque, Nicolas; Perez-Segarra, Carlos D.; Oliva, Assensi [Centre Tecnologic de Transferencia de Calor (CTTC), Universitat Politecnica de Catalunya (UPC), ETSEIAT, C. Colom 11, 08222 Terrassa (Barcelona) (Spain)

    2010-06-15

    The present paper is a numerical and experimental comparative study of the whole vapour compression refrigerating cycle in general, and reciprocating compressors in particular, with the aim of showing the possibilities that CO{sub 2} offers for commercial refrigeration, considering a single-stage trans-critical cycle using semi-hermetic reciprocating compressors under small cooling capacity systems. The present work is focussed on the influence of using an internal heat exchanger (IHX) in order to improve the cycle performance under real working conditions. In order to validate the numerical results, an experimental unit specially designed and built to analyze trans-critical refrigerating equipments considering IHX has been built. Both numerical results and experimental data show reasonable good agreement, while the comparative global values conclude the improvement of cooling capacity and COP when IHX is considered in the CO{sub 2} trans-critical cycle. (author)

  12. Avances en investigación de la discapacidad intelectual de origen genético: tratamientos experimentales en el síndrome X frágil

    Directory of Open Access Journals (Sweden)

    Yolanda de Diego Otero

    2017-06-01

    Full Text Available De Diego Otero, Y. et al. (2017: “Avances en investigación de la discapacidad intelectual de origen genético: tratamientos experimentales en el síndrome X frágil”. Revista Española de Discapacidad, 5 (I: 217-227.

  13. Development and a Validation of a Charge Sensitive Organic Rankine Cycle (ORC Simulation Tool

    Directory of Open Access Journals (Sweden)

    Davide Ziviani

    2016-05-01

    Full Text Available Despite the increasing interest in organic Rankine cycle (ORC systems and the large number of cycle models proposed in the literature, charge-based ORC models are still almost absent. In this paper, a detailed overall ORC simulation model is presented based on two solution strategies: condenser subcooling and total working fluid charge of the system. The latter allows the subcooling level to be predicted rather than specified as an input. The overall cycle model is composed of independent models for pump, expander, line sets, liquid receiver and heat exchangers. Empirical and semi-empirical models are adopted for the pump and expander, respectively. A generalized steady-state moving boundary method is used to model the heat exchangers. The line sets and liquid receiver are used to better estimate the total charge of the system and pressure drops. Finally, the individual components are connected to form a cycle model in an object-oriented fashion. The solution algorithm includes a preconditioner to guess reasonable values for the evaporating and condensing temperatures and a main cycle solver loop which drives to zero a set of residuals to ensure the convergence of the solution. The model has been developed in the Python programming language. A thorough validation is then carried out against experimental data obtained from two test setups having different nominal size, working fluids and individual components: (i a regenerative ORC with a 5 kW scroll expander and an oil flooding loop; (ii a regenerative ORC with a 11 kW single-screw expander. The computer code is made available through open-source dissemination.

  14. Ensayo de abrasión de Darmstadt para tuberías de alcantarillado pluvial: revisión de condiciones experimentales

    OpenAIRE

    Andrés Eduardo Torres Abello; Juan Dionisio Zambrano Ramírez

    2009-01-01

    El ensayo de abrasión de Darmstadt se ha utilizado principalmente para comparar la abrasión de diferentes tipos de tuberías. Sin embargo, no se han evidenciado claramente aún relaciones entre los resultados obtenidos mediante dicho ensayo y variables como la vida útil de los materiales o la composición del agua transportada. A partir de un montaje experimental, similar al de Darmstadt, se ensayaron tubos de concreto sin revestimiento, haciendo variar las condiciones experimentales. Se observó...

  15. EL DILEMA DE LA CONTRIBUCIÓN VOLUNTARIA A BIENES PÚBLICOS: UNA REVISIÓN DE TRABAJOS EXPERIMENTALES

    Directory of Open Access Journals (Sweden)

    Luis Alejandro Palacio García

    2014-01-01

    Full Text Available El artículo presenta una revisión de los experimentos realizados sobre bienes públicos apoyados en el mecanismo de contribución voluntaria. La evidencia empírica existente muestra que los individuos no son solo los seres egoístas y competitivos que supone la teoría económica ortodoxa, sino que también son seres bondadosos y altruistas. Aunque los diversos trabajos experimentales concuerdan en la existencia de estos sentimientos catalogados como "bondad", no es claro si los sujetos actúan así para mejorar el bienestar de los demás (altruismo o porque se sienten bien realizando este tipo acciones (satisfacción moral.

  16. Resurrecting Equilibria Through Cycles

    DEFF Research Database (Denmark)

    Barnett, Richard C.; Bhattacharya, Joydeep; Bunzel, Helle

    equilibria because they asymptotically violate some economic restriction of the model. The literature has always ruled out such paths. This paper studies a pure-exchange monetary overlapping generations economy in which real balances cycle forever between momentary equilibrium points. The novelty is to show...... that segments of the offer curve that have been previously ignored, can in fact be used to produce asymptotically valid cyclical paths. Indeed, a cycle can bestow dynamic validity on momentary equilibrium points that had erstwhile been classified as dynamically invalid....

  17. Experimental study of the pile EL3; Etude experimentale de la pile EL3

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1958-07-01

    The results of two months' experiments, carried out at low power following the first divergence (4. July 1957) are presented. These experiments dealt with the following points: comparison of experimental and calculated values of the critical size; effects due to the introduction of absorbing materials into the principal experimental facilities, flux distribution measurements especially in these facilities, calibration of safety, control and compensating rods, determination of the average life of the neutrons. (author) [French] On expose les resultats relatifs a deux mois d'experiences effectuees a basse puissance a la suite de la premiere divergence (4 juillet 1957). Ces experiences ont porte sur les points suivants: comparaison des tailles critiques experimentales et calculees, effets dus a l'introduction de corps absorbants dans les principaux dispositifs experimentaux, mesures des distributions de flux particulierement dans ces dispositifs, etalonnage des barres de securite, de reglage et de compensation, determination de la vie moyenne des neutrons. (auteur)

  18. Validation of a new version of software for monitoring the core of nuclear power plant of Laguna Verde Unit 2, at the end of Cycle 10

    International Nuclear Information System (INIS)

    Hernandez, G.; Calleros, G.; Mata, F.

    2009-10-01

    This work shows the differences observed in thermal limits established in the technical specifications of operation, among the new software, installed at the end of Cycle 10 of Unit 2 of nuclear power plant of Laguna Verde, and the old software that was installed from the beginning of the cycle. The methodology allowed to validate the new software during the coast down stage, before finishing the cycle, for what could be used as tool during the shutdown of Unit 2 at the end of Cycle 10. (Author)

  19. Las analogías en la enseñanza y el aprendizaje de las ciencias experimentales: un estado de la cuestión

    Directory of Open Access Journals (Sweden)

    Natalia Buitrago Henao

    2009-10-01

    Full Text Available Esta ponencia hace parte del trabajo final para optar al título de Máster Oficial en investigación en la enseñanza y el aprendizaje de las ciencias experimentales, sociales y matemáticas, de la Universidad Internacional de Andalucía? y, presenta un estado actual de la cuestión en torno al uso de las analogías como recurso didáctico en el aula de ciencias.

  20. Validez Estructurada para una investigación cuasi-experimental de calidad: se cumplen 50 años de la presentación en sociedad de los diseños cuasi-experimentales

    Directory of Open Access Journals (Sweden)

    Paula Fernández-García

    2014-05-01

    Full Text Available Investigación cuasi-experimental es aquella que tiene como objetivo poner a prueba una hipótesis causal manipulando (al menos una variable independiente donde por razones logísticas o éticas no se puede asignar las unidades de investigación aleatoriamente a los grupos. Debido a que muchas decisiones a nivel social se toman en base al resultado de investigaciones con estas características, es imperativo que tengan una planificación exquisita de la aplicación del tratamiento, del control en el proceso de la investigación y del análisis de los datos. El pasado año 2013 los diseños cuasi-experimentales cumplieron 50 años, y este trabajo es un homenaje a Campbell y a todos los investigadores que día a día aportan ideas para mejorar el método cuasi-experimental en alguno de sus aspectos. De la mano de una revisión de las investigaciones cuasi-experimentales publicadas en un período de 11 años en tres revistas de Psicología destacamos algunos aspectos que se refieren al cuidado del método. Finalizamos el trabajo proponiendo el concepto de Validez Estructurada, que en resumen, es el hilo conductor que debe seguir la realización de toda investigación para poner a prueba con garantía las hipótesis que responden a los objetivos que en ella se plantean, concretamente, en las investigaciones cuasi-experimentales.

  1. Validity of single-cycle objective functions for multicycle reload design optimization

    International Nuclear Information System (INIS)

    Kropaczek, D.J.; McElroy, J.; Turinsky, P.J.

    1993-01-01

    Beyond the equilibrium cycle scoping calculations used for determining numbers of feed assemblies and enrichment estimates, multicycle reload design currently consists of stagewise optimization of single-cycle core loading patterns, typically extending over a short-term planning horizon of perhaps three reload cycles. Particularly in transition cycles, however, optimizing a loading pattern over a single cycle for a stated objective, such as minimum core leakage, may have an adverse impact on subsequent cycles. The penalties paid may be in the form of reduced thermal margin or an increase in feed enrichment due to insufficient reactivity carryover from the open-quotes optimizedclose quotes cycle. In view of current practices, a study was performed that examined the behavior of the loading pattern as a function of the objective functions selected as implemented in the stagewise optimization of single-cycle core loading patterns from initial transition cycle through equilibrium using the FORMOSA-P code. The objective functions studied were region average discharge burnup maximization (with enrichment search) and feed enrichment minimization. It is noted at the beginning that the maximization of region average discharge has no meaning for the equilibrium cycle because region average discharge burnup is explicitly set by the feed size and cycle length independent of the loading pattern. In the nonequilibrium cycle, however, it was reasoned that this objective would provide the maximum reactivity carryover throughout the transition and thus have a direct effect on minimizing the multicycle levelized fuel cost

  2. Rocket-Based Combined Cycle Engine Technology Development: Inlet CFD Validation and Application

    Science.gov (United States)

    DeBonis, J. R.; Yungster, S.

    1996-01-01

    A CFD methodology has been developed for inlet analyses of Rocket-Based Combined Cycle (RBCC) Engines. A full Navier-Stokes analysis code, NPARC, was used in conjunction with pre- and post-processing tools to obtain a complete description of the flow field and integrated inlet performance. This methodology was developed and validated using results from a subscale test of the inlet to a RBCC 'Strut-Jet' engine performed in the NASA Lewis 1 x 1 ft. supersonic wind tunnel. Results obtained from this study include analyses at flight Mach numbers of 5 and 6 for super-critical operating conditions. These results showed excellent agreement with experimental data. The analysis tools were also used to obtain pre-test performance and operability predictions for the RBCC demonstrator engine planned for testing in the NASA Lewis Hypersonic Test Facility. This analysis calculated the baseline fuel-off internal force of the engine which is needed to determine the net thrust with fuel on.

  3. Production and validation of nuclear data for reactor and fuel cycle applications; Production et validation des donnees nucleaires pour les applications reacteurs et cycle du combustible

    Energy Technology Data Exchange (ETDEWEB)

    Trakas, C [Framatome ANP GmbH NBTT, Erlangen (Germany); Verwaerde, D [Electricite de France EDF, 75 - Paris (France); Toubon, H [Cogema, 78 - Velizy Villacoublay (France); and others

    2002-07-01

    The aim of this technical meeting is the improvement of the existing nuclear data and the production of new data of interest for the upstream and downstream of the fuel cycle (enrichment, fabrication, management, storage, transport, reprocessing), for the industrial reactors, the research reactors and the new reactor concepts (criticality, dimensioning, exploitation), for the instrumentation systems (external and internal sensors), the radioprotection, the residual power, the structures (neutron bombardment effect on vessels, rods etc..), and for the activation of steel structures (Fr, Ni, Co). The expected result is the collection of more reliable and accurate data in a wider spectrum of energies and temperatures thanks to more precise computer codes and measurement techniques. This document brings together the communications presented at this meeting and dealing with: the process of production and validation of nuclear data; the measurement facilities and the big international programs; the users needs and the industrial priorities; the basic nuclear data (BND) needs at Cogema; the expression and evaluation of BND; the evaluation work: the efficient cross-sections; the processing of data and the creation of activation libraries; from the integral measurement to the qualification and the feedback on nuclear data. (J.S.)

  4. Three-dimensional deformation response of a NiTi shape memory helical-coil actuator during thermomechanical cycling: experimentally validated numerical model

    Science.gov (United States)

    Dhakal, B.; Nicholson, D. E.; Saleeb, A. F.; Padula, S. A., II; Vaidyanathan, R.

    2016-09-01

    Shape memory alloy (SMA) actuators often operate under a complex state of stress for an extended number of thermomechanical cycles in many aerospace and engineering applications. Hence, it becomes important to account for multi-axial stress states and deformation characteristics (which evolve with thermomechanical cycling) when calibrating any SMA model for implementation in large-scale simulation of actuators. To this end, the present work is focused on the experimental validation of an SMA model calibrated for the transient and cyclic evolutionary behavior of shape memory Ni49.9Ti50.1, for the actuation of axially loaded helical-coil springs. The approach requires both experimental and computational aspects to appropriately assess the thermomechanical response of these multi-dimensional structures. As such, an instrumented and controlled experimental setup was assembled to obtain temperature, torque, degree of twist and extension, while controlling end constraints during heating and cooling of an SMA spring under a constant externally applied axial load. The computational component assesses the capabilities of a general, multi-axial, SMA material-modeling framework, calibrated for Ni49.9Ti50.1 with regard to its usefulness in the simulation of SMA helical-coil spring actuators. Axial extension, being the primary response, was examined on an axially-loaded spring with multiple active coils. Two different conditions of end boundary constraint were investigated in both the numerical simulations as well as the validation experiments: Case (1) where the loading end is restrained against twist (and the resulting torque measured as the secondary response) and Case (2) where the loading end is free to twist (and the degree of twist measured as the secondary response). The present study focuses on the transient and evolutionary response associated with the initial isothermal loading and the subsequent thermal cycles under applied constant axial load. The experimental

  5. Methodologies for verification and validation of expert systems as a function of component, criticality and life-cycle phase

    International Nuclear Information System (INIS)

    Miller, L.

    1992-01-01

    The review of verification and validation (V and V) methods presented here is based on results of the initial two tasks of a contract with the US Nuclear Regulatory Commission and the Electric Power Research Institute to Develop and Document Guidelines for Verifying and Validating Expert Systems. The first task was to review the applicability of conventional software techniques to expert systems; the second was to directly survey V and V practices associated with development of expert systems. Subsequent tasks will focus on selecting, synthesizing or developing V and V methods appropriate for the overall system, for specific expert systems components, and for different phases of the life-cycle. In addition, final guidelines will most likely be developed for each of three levels of expert systems: safety-related (systems whose functions directly relate to system safety, so-called safety-critical systems), important-to-safety (systems which support the critical safety functions), and non-safety (systems which are unrelated to safety functions). For the present purposes of categorizing and discussing various types of V and V methods, the authors simplify the life-cycle and consider only two aspects - systems validation phase. The authors identified a number of techniques for the first, combined, phase and two general classes of V and V techniques for the latter phase: static testing techniques, which do not involve execution of the system code, and dynamic testing techniques, which do. In the next two sections the author reviews first the applicability to expert systems of conventional V and V techniques and, second, the techniques expert system developers actually use. In the last section the authors make some general observations

  6. Ring-testing and field-validation of a terrestrial model ecosystem - An instrument for testing potentially harmful substances: effects of carbendazim on nutrient cycling.

    NARCIS (Netherlands)

    van Gestel, C.A.M.; Koolhaas, J.E.; Schallnass, H.-J.; Rodrigues, J.M.L.; Jones, S.E.

    2004-01-01

    The effect of the fungicide carbendazim (applied in the formulation Derosal®) on nutrient cycling in soil was determined in Terrestrial Model Ecosystem (TME) tests and corresponding field-validation studies, which were performed in four different countries (United Kingdom, Germany, Portugal, and The

  7. Development and Application of a Novel Rasch-Based Methodology for Evaluating Multi-Tiered Assessment Instruments: Validation and Utilization of an Undergraduate Diagnostic Test of the Water Cycle

    Science.gov (United States)

    Romine, William L.; Schaffer, Dane L.; Barrow, Lloyd

    2015-01-01

    We describe the development and validation of a three-tiered diagnostic test of the water cycle (DTWC) and use it to evaluate the impact of prior learning experiences on undergraduates' misconceptions. While most approaches to instrument validation take a positivist perspective using singular criteria such as reliability and fit with a measurement…

  8. ATHLET. Mod 3.0 Cycle A. Validation

    Energy Technology Data Exchange (ETDEWEB)

    Lerchl, G.; Austregesilo, H.; Glaeser, H.; Hrubisko, M.; Luther, W.

    2012-09-15

    ATHLET is an advanced best-estimate code which has been initially developed for the simulation of design basis and beyond design basis accidents (without core degradation) in light water reactors, including VVER and RBMK reactors. Furthermore, this program version enables the simulation of further working fluids like helium and liquid metals. The one-dimensional, two-phase fluiddynamic models are based on a five-equation model supplemented by a full-range drift-flux model, including a dynamic mixture-level tracking capability. Moreover, a two-fluid model based on six conservation equations is provided. The heat conduction and heat transfer module allows a flexible simulation of fuel rods and structures. The nuclear heat generation is calculated by a point-kinetics or by a one-dimensional kinetics model. A general control simulation module is provided for a flexible modelling of BOP- and auxiliary plant systems. Systematic code validation is performed by GRS and independent organizations. This Validation Manual is the fourth volume of the ATHLET Code Documentation comprising four volumes. This manual presents an overview about the complete ATHLET validation effort spent up to now. In addition, the results of five test cases simulated with the present ATHLET program version are compared with the experimental data.

  9. Direct-contact condensers for open-cycle OTEC applications: Model validation with fresh water experiments for structured packings

    Energy Technology Data Exchange (ETDEWEB)

    Bharathan, D.; Parsons, B.K.; Althof, J.A.

    1988-10-01

    The objective of the reported work was to develop analytical methods for evaluating the design and performance of advanced high-performance heat exchangers for use in open-cycle thermal energy conversion (OC-OTEC) systems. This report describes the progress made on validating a one-dimensional, steady-state analytical computer of fresh water experiments. The condenser model represents the state of the art in direct-contact heat exchange for condensation for OC-OTEC applications. This is expected to provide a basis for optimizing OC-OTEC plant configurations. Using the model, we examined two condenser geometries, a cocurrent and a countercurrent configuration. This report provides detailed validation results for important condenser parameters for cocurrent and countercurrent flows. Based on the comparisons and uncertainty overlap between the experimental data and predictions, the model is shown to predict critical condenser performance parameters with an uncertainty acceptable for general engineering design and performance evaluations. 33 refs., 69 figs., 38 tabs.

  10. Experimental study of superconductivity induced by proximity effects; Etude experimentale de la supraconductivite induite par effets de proximite

    Energy Technology Data Exchange (ETDEWEB)

    Martinet, A [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1966-11-15

    We present a study of the proximity effects between a superconductor (InBi or PbBi alloys) and a 'normal' metal (Zn or Sn respectively, above their critical temperature) using essentially the tunneling techniques. On the N side, some specific properties of such an induced superconductivity are described: linear variation of the pair potential near the critical temperature of the binary layer, T{sub CNS}; reduced energy scale at T{sub CNS}; evidence of a thermodynamic critical field (called breakdown field) presented by N above its critical temperature. On the S side, we study crossing from a gapless to a quasi gapless regime. This gives a proof of a finite coherence length at T{sub CNS}. Experimental details (in particular about the preparation and measurement of tunneling junctions) are given in annexe. Possible applications are suggested. (author) [French] Nous presentons une etude experimentale des effets de proximite entre un supraconducteur (alliages d'InBi ou de PbBi) et un metal 'normal' (Zn ou Sn respectivement, pris au-dessus de leur temperature critique), en utilisant principalement des mesures d'effet tunnel. Du cote N, on met en evidence des proprietes specifiques de cette supraconductivite induite: comportement lineaire du potentiel de paires pres de la temperature critique du bilame, T{sub CNS}; echelle d'energie reduite a T{sub CNS}; apparition d'un champ critique thermodynamique (appele champ de basculement) dans N au-dessus de sa temperature critique. Du cote S, nous etudions le passage continu d'une situation 'sans bande interdite' a basse temperature et en champ fort, a une situation 'pratiquement sans bande interdite' pres de T{sub CNS} en champ nul. Ceci fournit une preuve de la non divergence de la longueur de coherence a T{sub CNS}. Les techniques experimentales (et en particulier la preparation et la mesure de jonctions tunnel) sont decrites en detail dans une annexe. On envisage des applications pratiques possibles. (auteur)

  11. Experimental methods of reactor physics; Methodes experimentales de physique des reacteurs a neutrons thermiques

    Energy Technology Data Exchange (ETDEWEB)

    Breton, D; Lafore, P [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1964-07-01

    This paper is a synthesis of various experimental methods in use with the reactors of the Commissariat a l'Energie Atomique. The main techniques used are mentioned and the difficulties encountered and the accuracy obtained are particularly dwelt upon. The application of these various methods to reactors in order to obtain specific results is also indicated. This paper consists of five parts. I - General methods. Macroscopic and microscopic flux distribution (anisotropy effect), power distribution, etc... II - Kinetic measurements a) pulsed neutron technique: apparatus and accuracy; application to {lambda}t and to anti reactivity measurements; application to graphite, light water and beryllium oxide. b) oscillation techniques: equipment and accuracy; application to the measurements of effective cross sections and resonance integrals. c) fluctuations: apparatus and technique of measurement. III - Poison methods. Description of methods for introducing and extracting the poison, difficulties encountered with light and heavy water, measurement of temperature coefficients and anti-reactivity. IV - Spectra measurements. Choice and development of foils, problems of measurement, application to spectral measurements for thermalization studies, application to dosimetry. V - Experimental shielding measurements. The technique and apparatus recently developed in this field are presented. (authors) [French] Cette communication fait une synthese des differentes methodes experimentales mises en oeuvre sur les reacteurs du CEA. Elle presente les principales techniques utilisees et insiste plus particulierement sur les difficultes rencontrees et la precision obtenue; elle indique egalement l'application de ces differentes methodes sur les reacteurs, en vue de l'obtention des resultats determines. Elle comporte cinq parties: I - METHODES GENERALES: Distribution de flux macroscopique et microscopique (effet d'anisotropie), distribution de puissance, etc... II - MESURES CINETIQUES: a

  12. El rol de los valores numéricos de las medidas experimentales en el aprendizaje por indagación

    Directory of Open Access Journals (Sweden)

    Javier ARLEGUI DE PABLOS

    2010-01-01

    Full Text Available El aprendizaje por indagación en ciencias experimentales se entiende como un aprendizaje de resolución de problemas basado en la construcción y uso de modelos, y tiene actualmente su modelización didáctica en la teoría de las organizaciones praxeológicas. En este marco, los valores numéricos de las medidas juegan un papel preciso y de suma importancia; actúan como herramienta (útil en la construcción semántica de las magnitudes del fenómeno, y como objeto de conocimiento en el proceso de modelización de dicho fenómeno. Se muestra esta doble función en el caso de la elasticidad de un resorte.

  13. Experimental study of contamination by inhalation of radioactive iodine aerosols. Biological balance; Etude experimentale de la contamination par inhalation d'aerosols d'iode radioactif bilan biologique

    Energy Technology Data Exchange (ETDEWEB)

    Marble, G [Commissariat a l' Energie Atomique, 92 - Fontenay-aux-Roses (France). Centre d' Etudes Nucleaires

    1968-07-01

    Several articles have been published concerning research into contamination produced by inhalation of radioactive iodine aerosols in monkeys. Results dealing with the biological balance of this contamination are presented and discussed in this report. (author) [French] L'etude experimentale de la contamination par inhalation d'aerosols d'iode radioactif effectuee chez le singe a fait l'objet de plusieurs publications. Les resultats concernant le bilan biologique de cette contamination sont presentes et discutes dans ce rapport. (auteur)

  14. Validity of the RAST for evaluating anaerobic power performance as compared to Wingate test in cycling athletes

    Directory of Open Access Journals (Sweden)

    Marcos Roberto Queiroga

    2013-12-01

    Full Text Available The validity of the Running-based Anaerobic Sprint Test (RAST was investigated to evaluate the anaerobic power performance in comparison to Wingate test in cycling athletes. Ten mountain-bike male cyclists (28.0±7.3 years randomly performed Wingate Test and RAST with two trials each. After several anthropometric measurements, peak power (PP, mean power (MP and fatigue index (FI for RAST and Wingate Test were analyzed using Student's paired t-test, Pearson's linear correlation test (r and Bland and Altman's plots. Results showed that, with the exception of FI (33.8±4.6% vs. 37.8±7.9%; r=0.172, significant differences were detected between the Wingate and RAST tests with regard to PP and MP. Although there was a strong correlation for PP and MP, or rather, 0.831 and 0.714 respectively, agreement of analysis between Wingate and RAST protocols was low. The above suggested that RAST was not appropriate to evaluate the performance of anaerobic power by Wingate test in cycling athletes.

  15. Mathematical modeling of the complete thermodynamic cycle of a new Atkinson cycle gas engine

    International Nuclear Information System (INIS)

    Shojaeefard, Mohammad Hassan; Keshavarz, Mojtaba

    2015-01-01

    The Atkinson cycle provides the potential to increase the efficiency of SI engines using overexpansion concept. This also will suggest decrease in CO_2 generation by internal combustion engine. In this study a mathematical modeling of complete thermodynamic cycle of a new two-stroke Atkinson cycle SI engine will be presented. The mathematical modeling is carried out using two-zone combustion analysis in order to make the model predict exhaust emission so that its values could be compared with the values of conventional SI engine. The model also is validated against experimental tests in that increase in efficiency is achieved compared to conventional SI engines. - Highlights: • The complete cycle model for the rotary Atkinson engine was developed. • Comparing the results with experimental data shows good model validity. • The model needs further improvement for the scavenging phase. • There is 5% increment in thermal efficiency with new engine compared to conventional SI engines.

  16. Experimental validation of calculation schemes connected with PWR absorbers and burnable poisons; Validation experimentale des schemas de calcul relatifs aux absorbants et poisons consommables dans les REP

    Energy Technology Data Exchange (ETDEWEB)

    Klenov, P.

    1995-10-01

    In France 80% of electricity is produced by PWR reactors. For a better exploitation of these reactors a modular computer code Apollo-II has been developed. his code compute the flux transport by discrete ordinate method or by probabilistic collisions on extended configurations such as reactor cells, assemblies or little cores. For validation of this code on mixed oxide fuel lattices with absorbers an experimental program Epicure in the reactor Eole was induced. This thesis is devoted to the validation of the Apollo code according to the results of the Epicure program. 43 refs., 65 figs., 1 append.

  17. Gestión de Materiales Experimentales y su Uso en Replicaciones de Experimentos: Un Mapeo Sistemático de la Literatura

    Directory of Open Access Journals (Sweden)

    Edison Espinosa

    2016-11-01

    Full Text Available La Ingeniería de Software Experimental (ISE aplica la experimentación para obtener conocimiento sobre productos, métodos, técnicas usados en el proceso de desarrollo software. Para validar el conocimiento es necesario repetir el experimento original tantas veces como sea necesario. Se requieren mucha información y materiales acerca del experimento para que un experimentador realice una replicación. Previa a la ejecución de la replicación del experimento, algunos o la totalidad de los materiales pueden requerir cambios produciendo nuevas o modificadas versiones de estos. Una vez ejecutada la replicación del experimento se espera que, parte o la totalidad de los materiales, se incorporen al material del experimento original. El incremento en el número de replicaciones del experimento original está directamente relacionado con el incremento de las versiones del material experimental, que ocasiona comúnmente confusión y desorden en su organización. En este trabajo, realizamos un mapeo sistemático de la literatura (MSL para localizar trabajos sobre Gestión de Materiales Experimentales y su Uso en Replicaciones en Ingeniería de Software Experimental. Los resultados encontrados reflejan la escasa existencia de artículos sobre esta temática. Además, el análisis de los estudios encontrados ha descubierto que dichos artículos, en su mayoría, adolecen de problemas en la gestión de versiones de materiales experimentales para poder llevar a cabo un proceso de replicación. Estos datos proporcionan información de interés para iniciar la investigación de la adopción del paradigma de gestión de configuración de software en la gestión del material experimental en ISE.

  18. Production and validation of nuclear data for reactor and fuel cycle applications

    International Nuclear Information System (INIS)

    Trakas, C.; Verwaerde, D.; Toubon, H.

    2002-01-01

    The aim of this technical meeting is the improvement of the existing nuclear data and the production of new data of interest for the upstream and downstream of the fuel cycle (enrichment, fabrication, management, storage, transport, reprocessing), for the industrial reactors, the research reactors and the new reactor concepts (criticality, dimensioning, exploitation), for the instrumentation systems (external and internal sensors), the radioprotection, the residual power, the structures (neutron bombardment effect on vessels, rods etc..), and for the activation of steel structures (Fr, Ni, Co). The expected result is the collection of more reliable and accurate data in a wider spectrum of energies and temperatures thanks to more precise computer codes and measurement techniques. This document brings together the communications presented at this meeting and dealing with: the process of production and validation of nuclear data; the measurement facilities and the big international programs; the users needs and the industrial priorities; the basic nuclear data (BND) needs at Cogema; the expression and evaluation of BND; the evaluation work: the efficient cross-sections; the processing of data and the creation of activation libraries; from the integral measurement to the qualification and the feedback on nuclear data. (J.S.)

  19. Development and Validation of Water Vapor Tracers as Diagnostics for the Atmospheric Hydrologic Cycle

    Science.gov (United States)

    Bosilovich, Michael G.; Schubert, Siegfried D.; Einaudi, Franco (Technical Monitor)

    2000-01-01

    Understanding of the local and remote sources of water vapor can be a valuable diagnostic in understanding the regional atmospheric hydrologic cycle. In the present study, we have implemented passive tracers as prognostic variables to follow water vapor evaporated in predetermined regions until the water tracer precipitates. The formulation of the sources and sinks of tracer water is generally proportional to the prognostic water vapor variable. Because all water has been accounted for in tracers, the water vapor variable provides the validation of the tracer water and the formulation of the sources and sinks. The tracers have been implemented in a GEOS General Circulation Model (GCM) simulation consisting of several summer periods to determine the source regions of precipitation for the United States and India. The recycling of water and interannual variability of the sources of water will be examined. Potential uses in GCM sensitivity studies, predictability studies and data assimilation will be discussed.

  20. ANÁLISIS DE ESTABILIDAD DE HÍBRIDOS EXPERIMENTALES DE MAÍZ CON ALTA CALIDAD DE PROTEÍNA EN COSTA RICA

    Directory of Open Access Journals (Sweden)

    Nevio Bonilla-Morales

    2012-01-01

    Full Text Available El objetivo de este trabajo fue determinar la adaptación de híbridos experimentales de maíz en Costa Rica. Se evaluaron veinticuatro híbridos experimentales de grano blanco en las condiciones agroecológicas de bosque tropical húmedo, durante el período 2009-2011, en las localidades de Concepción, Guagaral, Chánguena, El Águila, Veracruz, Los Chiles y Upala, con temperaturas entre 26 y 35°C y una precipitación entre los 2700-3200 mm, esto con el fin de obtener el rendimiento y respuesta a los principales factores abióticos y bióticos. Se empleó un diseño de alfa látice con tres repeticiones. Los híbridos fueron evaluados en dos ciclos de siembra por localidad y por año. Los resultados del análisis combinado indicaron diferencias significativas al 0,05 entre genotipos y el gráfico del AMMI-biplot evidenció que los materiales con mayor estabilidad fueron: CLQRCWQ121/CLQRCWQ122//CML491 (QPM; CML494/CML495 (Normal; (CLQRCWQ121/CLQRCWQ26//CML491 (QPM; (CLQRCWQ121/CML502//CML491 (QPM con rendimientos promedio de 9,3; 9,0; 8,7 y 8,8 t/ha, respectivamente. Las localidades donde se obtuvo mayor rendimiento fueron El Águila y Guagaral, 9,8 y 8,5 t/ha, respectivamente. En cuanto a la interacción de localidades y genotipos el AMMI biplot mostró que El Águila y Guagaral tuvieron condiciones agroclimáticas más favorables para la expresión del potencial de los híbridos evaluados. Por su parte, Veracruz y Concepción presentaron condiciones agroclimáticas menos favorables para el desempeño de los materiales. La interacción genotipo x ambiente tuvo un valor de 62,1% en la prueba de Gollob.

  1. Development and experimental qualification of the new safety-criticality CRISTAL package; Developpement et qualification experimentale du nouveau formulaire de surete-criticite Cristal

    Energy Technology Data Exchange (ETDEWEB)

    Mattera, Ch

    1998-11-01

    This thesis is concerned with Criticality-Safety studies related to the French Nuclear Fuel Cycle. We first describe the steps in the nuclear fuel cycle and the specific characteristics of these studies compared with those performed in Reactor Physics. In order to respond to the future requirements of the French Nuclear Program, we have developed a new package CRISTAL based on a recent cross sections library (CEA 93) and the newest accurate codes (APOLLO 2, MORET 4, TRIPOLI 4). The CRISTAL system includes two calculations routes: a design route which will be used by French Industry (COGEMA/SGN) and a reference route. To transfer this package to the French industry, we have elaborated calculation schemes for fissile solutions, dissolver media, transport casks and storage pools. Afterwards, these schemes have been used for the CRISTAL experimental validation. We have also contributed to the CRISTAL experimental database by reevaluating a French storage pool experiment: the CRISTO II experiment. This revaluation has been submitted to the OECD working group in order that this experiment can be used by international criticality safety engineers to validate calculations methods. This work represents a large contribution to the recommendation of accurate calculation schemes and to the experimental validation of the CRISTAL package. These studies came up to the French Industry expectations. (author)

  2. Thermal cycling in multifilamentary superconducting composites

    International Nuclear Information System (INIS)

    Aragao, E.E.A. de.

    1984-01-01

    NbTi-Cu multifilamentary superconducting composites were embedded, polished, characterized by microscopic techniques, and analyzed in a qualitative and semiquantitative way by energy dispersion technique. The superconductors were submitted to thermal cycling between the ambient temperature and the boiling point of helium (4.2K), for different number of cycles. The aims were to study the correlation between the possible microstructural damages due to thermal stresses arising in the composite during cycling and the variation of properties of the material with the number of cycles as well as to verify the validity of an elastic model for thermal stresses for low temperature cycles. (author)

  3. RELIABILITY AND VALIDITY OF PHYSIOLOGICAL DATA OBTAINED WITHIN A CYCLE-RUN TRANSITION TEST IN AGE-GROUP TRIATHLETES

    Directory of Open Access Journals (Sweden)

    Veronica Vleck

    2012-12-01

    Full Text Available This study examined the validity and reliability of a sequential "Run-Bike-Run" test (RBR in age-group triathletes. Eight Olympic distance (OD specialists (age 30.0 ± 2.0 years, mass 75.6 ± 1.6 kg, run VO2max 63.8 ± 1.9 ml·kg-1·min-1, cycle VO2peak 56.7 ± 5.1 ml·kg-1·min-1 performed four trials over 10 days. Trial 1 (TRVO2max was an incremental treadmill running test. Trials 2 and 3 (RBR1 and RBR2 involved: 1 a 7-min run at 15 km·h-1 (R1 plus a 1-min transition to 2 cycling to fatigue (2 W·kg-1 body mass then 30 W each 3 min; 3 10-min cycling at 3 W·kg-1 (Bsubmax; another 1-min transition and 4 a second 7-min run at 15 km·h-1 (R2. Trial 4 (TT was a 30-min cycle - 20-min run time trial. No significant differences in absolute oxygen uptake (VO2, heart rate (HR, or blood lactate concentration ([BLA] were evidenced between RBR1 and RBR2. For all measured physiological variables, the limits of agreement were similar, and the mean differences were physiologically unimportant, between trials. Low levels of test-retest error (i.e. ICC <0.8, CV<10% were observed for most (logged measurements. However [BLA] post R1 (ICC 0.87, CV 25.1%, [BLA] post Bsubmax (ICC 0.99, CV 16.31 and [BLA] post R2 (ICC 0.51, CV 22.9% were least reliable. These error ranges may help coaches detect real changes in training status over time. Moreover, RBR test variables can be used to predict discipline specific and overall TT performance. Cycle VO2peak, cycle peak power output, and the change between R1 and R2 (deltaR1R2 in [BLA] were most highly related to overall TT distance (r = 0.89, p < 0. 01; r = 0.94, p < 0.02; r = 0.86, p < 0.05, respectively. The percentage of TR VO2max at 15 km·h-1, and deltaR1R2 HR, were also related to run TT distance (r = -0.83 and 0.86, both p < 0.05

  4. The Development and Validation of a Three-Tier Diagnostic Test Measuring Pre-Service Elementary Education and Secondary Science Teachers' Understanding of the Water Cycle

    Science.gov (United States)

    Schaffer, Dannah Lynn

    2013-01-01

    The main goal of this research study was to develop and validate a three-tier diagnostic test to determine pre-service teachers' (PSTs) conceptual knowledge of the water cycle. For a three-tier diagnostic test, the first tier assesses content knowledge; in the second tier, a reason is selected for the content answer; and the third tier allows…

  5. Experimental study of contamination by inhalation of radioactive iodine aerosols. Biological balance; Etude experimentale de la contamination par inhalation d'aerosols d'iode radioactif bilan biologique

    Energy Technology Data Exchange (ETDEWEB)

    Marble, G. [Commissariat a l' Energie Atomique, 92 - Fontenay-aux-Roses (France). Centre d' Etudes Nucleaires

    1968-07-01

    Several articles have been published concerning research into contamination produced by inhalation of radioactive iodine aerosols in monkeys. Results dealing with the biological balance of this contamination are presented and discussed in this report. (author) [French] L'etude experimentale de la contamination par inhalation d'aerosols d'iode radioactif effectuee chez le singe a fait l'objet de plusieurs publications. Les resultats concernant le bilan biologique de cette contamination sont presentes et discutes dans ce rapport. (auteur)

  6. MDEP Generic Common Position No DICWG-03. Common position on verification and validation throughout the life cycle of digital safety systems

    International Nuclear Information System (INIS)

    2013-01-01

    Verification and validation (V and V) is essential throughout the life cycle of nuclear power plant safety systems. This common position applies to V and V activities for digital safety systems throughout their life cycles. This encompasses both the software and hardware of such systems. The Digital Instrumentation and Controls Working Group (DICWG) has agreed that a common position on this topic is warranted given the use of Digital I and C in new reactor designs, its safety implications, and the need to develop a common understanding from the perspectives of regulatory authorities. This action follows the DICWG examination of the regulatory requirements of the participating members and of relevant industry standards and IAEA documents. The DICWG proposes a common position based on its recent experience with the new reactor application reviews and operating plant issues

  7. Life cycle management of analytical methods.

    Science.gov (United States)

    Parr, Maria Kristina; Schmidt, Alexander H

    2018-01-05

    In modern process management, the life cycle concept gains more and more importance. It focusses on the total costs of the process from invest to operation and finally retirement. Also for analytical procedures an increasing interest for this concept exists in the recent years. The life cycle of an analytical method consists of design, development, validation (including instrumental qualification, continuous method performance verification and method transfer) and finally retirement of the method. It appears, that also regulatory bodies have increased their awareness on life cycle management for analytical methods. Thus, the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH), as well as the United States Pharmacopeial Forum discuss the enrollment of new guidelines that include life cycle management of analytical methods. The US Pharmacopeia (USP) Validation and Verification expert panel already proposed a new General Chapter 〈1220〉 "The Analytical Procedure Lifecycle" for integration into USP. Furthermore, also in the non-regulated environment a growing interest on life cycle management is seen. Quality-by-design based method development results in increased method robustness. Thereby a decreased effort is needed for method performance verification, and post-approval changes as well as minimized risk of method related out-of-specification results. This strongly contributes to reduced costs of the method during its life cycle. Copyright © 2017 Elsevier B.V. All rights reserved.

  8. Combined Turbine and Cycle Optimization for Organic Rankine Cycle Power Systems—Part A: Turbine Model

    Directory of Open Access Journals (Sweden)

    Andrea Meroni

    2016-04-01

    Full Text Available Axial-flow turbines represent a well-established technology for a wide variety of power generation systems. Compactness, flexibility, reliability and high efficiency have been key factors for the extensive use of axial turbines in conventional power plants and, in the last decades, in organic Rankine cycle power systems. In this two-part paper, an overall cycle model and a model of an axial turbine were combined in order to provide a comprehensive preliminary design of the organic Rankine cycle unit, taking into account both cycle and turbine optimal designs. Part A presents the preliminary turbine design model, the details of the validation and a sensitivity analysis on the main parameters, in order to minimize the number of decision variables in the subsequent turbine design optimization. Part B analyzes the application of the combined turbine and cycle designs on a selected case study, which was performed in order to show the advantages of the adopted methodology. Part A presents a one-dimensional turbine model and the results of the validation using two experimental test cases from literature. The first case is a subsonic turbine operated with air and investigated at the University of Hannover. The second case is a small, supersonic turbine operated with an organic fluid and investigated by Verneau. In the first case, the results of the turbine model are also compared to those obtained using computational fluid dynamics simulations. The results of the validation suggest that the model can predict values of efficiency within ± 1.3%-points, which is in agreement with the reliability of classic turbine loss models such as the Craig and Cox correlations used in the present study. Values similar to computational fluid dynamics simulations at the midspan were obtained in the first case of validation. Discrepancy below 12 % was obtained in the estimation of the flow velocities and turbine geometry. The values are considered to be within a

  9. Development and experimental testing of the new safety-criticality Cristal package; Developpement et qualification experimentale du nouveau formulaire de surete-criticite Cristal

    Energy Technology Data Exchange (ETDEWEB)

    Mattera, Ch

    1998-11-10

    This thesis is concerned with Criticality-Safety studies related to the French Nuclear Fuel Cycle. We first describe the steps in the nuclear fuel cycle and the specific characteristics of these studies compared with those performed in Reactor Physics. In order to respond to the future requirements of the French Nuclear Program, we have developed a new package CRISTAL based on a recent cross sections library (CEA93) and the newest accurate codes (APOLLO2, MORET4, TRIPOLI4). The cristal system includes two calculations routes: a design route which will be used by French Industry (COGEMA/SGN) and a reference route.) To transfer this package to the French industry, we have elaborated calculation schemes for fissile solutions, dissolver media, transport casks and storage pools. Afterwards, these schemes have been used for the CRISTAL experimental validation. We have also contributed to the CRISTAL experimental database by reevaluating a French storage pool experiment: the CRISTO II experiment. This revaluation has been submitted to the OCDE working group in order that this experiment can be used by international criticality safety engineers to validate calculations methods. This work represents a large contribution to the recommendation of accurate calculation schemes and to the experimental validation of the CRISTAL package. These studies came up to the French Industry expectations. (author) 70 refs.

  10. Enfermedad de Huntington: modelos experimentales y perspectivas terapéuticas

    Directory of Open Access Journals (Sweden)

    Teresa Serrano Sánchez

    2011-01-01

    Full Text Available La enfermedad de Huntington (EH es un trastorno degenerativo de origen hereditario. Hasta el momento no existe un tratamiento efectivo para la enfermedad que inexorablemente después de transcurridos 15 a 20 años, evoluciona hacia la incapacidad total o la muerte. En este trabajo se revisan las características clínicas y morfológicas de la EH y los modelos experimentales más utilizados para su estudio tomando como fuente, los artículos indexados en la base de datos Medline publicados en los últimos 20 años. Se valoran las ventajas y desventajas de estos modelos y su perspectiva para el desarrollo de ensayos clínicos. El consenso de lo reportado plantea que de los modelos tóxicos, los inducidos por neurotoxinas tales como el ácido quinolínico parecen ser los más adecuados para reproducir las características neuropatológicas, y por otro lado los modelos genéticos contribuyen con más evidencias al conocimiento del origen etiológico de la enfermedad. Numerosos tratamientos han sido aplicados en el manejo de las manifestaciones clínicas que aparecen en la EH, sin poder detener o disminuir las afectaciones que derivan de la pérdida neuronal. La sintomatología clínica ha sido posible reproducirla, al menos en parte, en animales de experimentación lo que ha permitido realizar ensayos terapéuticos. Desde el punto de vista de tratamiento, lo que más promisorio parece ser, es el trasplante de fuentes celulares y dentro de ellas las no neurales, que implican menor censura ética y mayor factibilidad de obtención para la aplicación en los enfermos. Por otro lado el desarrollo de la tecnología del ARN interferente, emerge como una herramienta terapéutica potencial para el tratamiento de la EH, así como para responder interrogantes básicas relacionadas con el desarrollo de la enfermedad.

  11. Validity and reliability of the look Keo power pedal system for measuring power output during incremental and repeated sprint cycling.

    Science.gov (United States)

    Sparks, S Andy; Dove, Benjamin; Bridge, Craig A; Midgely, Adrian W; McNaughton, Lars R

    2015-01-01

    Power meters have traditionally been integrated into the crank set, but several manufacturers have designed new systems located elsewhere on the bike, such as inside the pedals. This study aimed to determine the validity and reliability of the Keo power pedals during several laboratory cycling tasks. Ten active male participants (mean ± SD age 34.0 ± 10.6 y, height 1.77 ± 0.04 m, body mass 76.5 ± 10.7 kg) familiar with laboratory cycling protocols completed this study. Each participant was required to complete 2 laboratory cycling trials on an SRM ergometer (SRM, Germany) that was also fitted with the Keo power pedals (Look, France). The trials consisted of an incremental test to exhaustion followed by 10 min rest and then three 10-s sprint tests separated by 3 min of cycling at 100 W. Over power ranges of 75 to 1147 W, the Keo power-pedal system produced typical error values of 0.40, 0.21, and 0.21 for the incremental, sprint, and combined trials, respectively, compared with the SRM. Mean differences of 21.0 and 18.6 W were observed between trials 1 and 2 with the Keo system in the incremental and combined protocols, respectively. In contrast, the SRM produced differences of 1.3 and 0.6 W for the same protocols. The power data from the Keo power pedals should be treated with some caution given the presence of mean differences between them and the SRM. Furthermore, this is exacerbated by poorer reliability than that of the SRM power meter.

  12. Aplicación práctica de métodos estereológicos renales en modelos animales experimentales

    Directory of Open Access Journals (Sweden)

    María Teresa Fernández García

    2017-01-01

    Full Text Available Los riñones son órganos vitales que realizan funciones de excreción, equilibrio hidroelectrolítico y producción de hormonas. La nefrona es su unidad estructural y funcional. El número, tamaño y distribución de los componentes de la nefrona contienen información relevante sobre la función renal. La estereología es una rama de la morfometría que permite, aplicando reglas matemáticas, obtener información tridimensional de estructuras biológicas a partir de cortes microscópicos bidimensionales, seriados, paralelos y equidistantes. Ante la complejidad de los estudios estereológicos y la carencia de una bibliografía clara sobre el desarrollo de los mismos, el objetivo de este trabajo es explicar de forma sencilla y con ejemplos, utilizando un modelo animal, los conceptos básicos de estereología, así como el cálculo de los principales parámetros estereológicos renales y que estos puedan ser aplicados en futuros estudios experimentales.

  13. Estimación del tiempo de desarrollo de Lutzomyia evansi bajo condiciones experimentales

    Directory of Open Access Journals (Sweden)

    Claudia Martínez Suárez

    2012-01-01

    Full Text Available Objetivo: Estimar el tiempo promedio de desarrollo de Lutzomyia evansi. Materiales y métodos: Se inició una colonia de Lutzomyia evansi con individuos recolectados en la zona urbana de la ciudad de Sincelejo (Colombia. La colonia fue mantenida en el laboratorio durante tres generaciones filiales bajo condiciones experimentales promedio de 26ºC de temperatura y 94% de humedad relativa. Resultados: La duración del desarrollo de Lutzomyia evansi fue de 36 a 45 días. El tiempo requerido para el desarrollo de los huevos fue en promedio de 6,75 días (rango de 6 a 8 días. La duración en promedio de los diferentes estadios larvales fue 5,75 días en larvas de primer estadio (rango de 5 a 8 días, 5,75 días en larvas de segundo estadio (rango de 4 a 7 días, 5 días en larvas de tercer estadio (rango de 4 a 7 días y 7 días en larvas de cuarto estadio (rango de 6 a 8 días. En la fase de pupa, la duración en promedio fue de 9,75 días (rango de 7 a 17 días. Conclusiones: El tiempo promedio requerido para el desarrollo de Lutzomyia evansi, comprendido desde la alimentación sanguínea de la hembra madre hasta la emergencia del adulto, es de 40 días.

  14. Understanding Solar Cycle Variability

    Energy Technology Data Exchange (ETDEWEB)

    Cameron, R. H.; Schüssler, M., E-mail: cameron@mps.mpg.de [Max-Planck-Institut für Sonnensystemforschung, Justus-von-Liebig-Weg 3, D-37077 Göttingen (Germany)

    2017-07-10

    The level of solar magnetic activity, as exemplified by the number of sunspots and by energetic events in the corona, varies on a wide range of timescales. Most prominent is the 11-year solar cycle, which is significantly modulated on longer timescales. Drawing from dynamo theory, together with the empirical results of past solar activity and similar phenomena for solar-like stars, we show that the variability of the solar cycle can be essentially understood in terms of a weakly nonlinear limit cycle affected by random noise. In contrast to ad hoc “toy models” for the solar cycle, this leads to a generic normal-form model, whose parameters are all constrained by observations. The model reproduces the characteristics of the variable solar activity on timescales between decades and millennia, including the occurrence and statistics of extended periods of very low activity (grand minima). Comparison with results obtained with a Babcock–Leighton-type dynamo model confirm the validity of the normal-mode approach.

  15. Nuclear fuel cycle system analysis

    International Nuclear Information System (INIS)

    Ko, W. I.; Kwon, E. H.; Kim, S. G.; Park, B. H.; Song, K. C.; Song, D. Y.; Lee, H. H.; Chang, H. L.; Jeong, C. J.

    2012-04-01

    The nuclear fuel cycle system analysis method has been designed and established for an integrated nuclear fuel cycle system assessment by analyzing various methodologies. The economics, PR(Proliferation Resistance) and environmental impact evaluation of the fuel cycle system were performed using improved DB, and finally the best fuel cycle option which is applicable in Korea was derived. In addition, this research is helped to increase the national credibility and transparency for PR with developing and fulfilling PR enhancement program. The detailed contents of the work are as follows: 1)Establish and improve the DB for nuclear fuel cycle system analysis 2)Development of the analysis model for nuclear fuel cycle 3)Preliminary study for nuclear fuel cycle analysis 4)Development of overall evaluation model of nuclear fuel cycle system 5)Overall evaluation of nuclear fuel cycle system 6)Evaluate the PR for nuclear fuel cycle system and derive the enhancement method 7)Derive and fulfill of nuclear transparency enhancement method The optimum fuel cycle option which is economical and applicable to domestic situation was derived in this research. It would be a basis for establishment of the long-term strategy for nuclear fuel cycle. This work contributes for guaranteeing the technical, economical validity of the optimal fuel cycle option. Deriving and fulfillment of the method for enhancing nuclear transparency will also contribute to renewing the ROK-U.S Atomic Energy Agreement in 2014

  16. Low Cycle Fatigue Behaviour of DP Steels: Micromechanical Modelling vs. Validation

    Directory of Open Access Journals (Sweden)

    Ghazal Moeini

    2017-07-01

    Full Text Available This study aims to simulate the stabilised stress-strain hysteresis loop of dual phase (DP steel using micromechanical modelling. For this purpose, the investigation was conducted both experimentally and numerically. In the experimental part, the microstructure characterisation, monotonic tensile tests and low cycle fatigue tests were performed. In the numerical part, the representative volume element (RVE was employed to study the effect of the DP steel microstructure of the low cycle fatigue behavior of DP steel. A dislocation-density based model was utilised to identify the tensile behavior of ferrite and martensite. Then, by establishing a correlation between the monotonic and cyclic behavior of ferrite and martensite phases, the cyclic deformation properties of single phases were estimated. Accordingly, Chaboche kinematic hardening parameters were identified from the predicted cyclic curve of individual phases in DP steel. Finally, the predicted hysteresis loop from low cycle fatigue modelling was in very good agreement with the experimental one. The stabilised hysteresis loop of DP steel can be successfully predicted using the developed approach.

  17. The carbon cycle in a land surface model: modelling, validation and implementation at a global scale; Cycle du carbone dans un modele de surface continentale: modelisation, validation et mise en oeuvre a l'echelle globale

    Energy Technology Data Exchange (ETDEWEB)

    Gibelin, A L

    2007-05-15

    ISBA-A-gs is an option of the CNRM land surface model ISBA which allows for the simulation of carbon exchanges between the terrestrial biosphere and the atmosphere. The model was implemented for the first time at the global scale as a stand-alone model. Several global simulations were performed to assess the sensitivity of the turbulent fluxes and Leaf Area Index to a doubling of the CO{sub 2} atmospheric concentration, and to the climate change simulated by the end of the 21. century. In addition, a new option of ISBA, referred to as ISBA-CC, was developed in order to simulate a more detailed ecosystem respiration by separating the autotrophic respiration and the heterotrophic respiration. The vegetation dynamics and the carbon fluxes were validated at a global scale using satellite datasets, and at a local scale using data from 26 sites of the FLUXNET network. All these results show that the model is sufficiently realistic to be coupled with a general circulation model, in order to account for interactions between the terrestrial biosphere, the atmosphere and the carbon cycle. (author)

  18. The seismic cycle at subduction thrusts: 2. Dynamic implications of geodynamic simulations validated with laboratory models

    KAUST Repository

    van Dinther, Y.

    2013-04-01

    The physics governing the seismic cycle at seismically active subduction zones remains poorly understood due to restricted direct observations in time and space. To investigate subduction zone dynamics and associated interplate seismicity, we validate a continuum, visco-elasto-plastic numerical model with a new laboratory approach (Paper 1). The analogous laboratory setup includes a visco-elastic gelatin wedge underthrusted by a rigid plate with defined velocity-weakening and -strengthening regions. Our geodynamic simulation approach includes velocity-weakening friction to spontaneously generate a series of fast frictional instabilities that correspond to analog earthquakes. A match between numerical and laboratory source parameters is obtained when velocity-strengthening is applied in the aseismic regions to stabilize the rupture. Spontaneous evolution of absolute stresses leads to nucleation by coalescence of neighboring patches, mainly occurring at evolving asperities near the seismogenic zone limits. Consequently, a crack-, or occasionally even pulse-like, rupture propagates toward the opposite side of the seismogenic zone by increasing stresses ahead of its rupture front, until it arrests on a barrier. The resulting surface displacements qualitatively agree with geodetic observations and show landward and, from near the downdip limit, upward interseismic motions. These are rebound and reversed coseismically. This slip increases adjacent stresses, which are relaxed postseismically by afterslip and thereby produce persistent seaward motions. The wide range of observed physical phenomena, including back-propagation and repeated slip, and the agreement with laboratory results demonstrate that visco-elasto-plastic geodynamic models with rate-dependent friction form a new tool that can greatly contribute to our understanding of the seismic cycle at subduction zones.

  19. The seismic cycle at subduction thrusts: 2. Dynamic implications of geodynamic simulations validated with laboratory models

    KAUST Repository

    van Dinther, Y.; Gerya, T. V.; Dalguer, L. A.; Corbi, F.; Funiciello, F.; Mai, Paul Martin

    2013-01-01

    The physics governing the seismic cycle at seismically active subduction zones remains poorly understood due to restricted direct observations in time and space. To investigate subduction zone dynamics and associated interplate seismicity, we validate a continuum, visco-elasto-plastic numerical model with a new laboratory approach (Paper 1). The analogous laboratory setup includes a visco-elastic gelatin wedge underthrusted by a rigid plate with defined velocity-weakening and -strengthening regions. Our geodynamic simulation approach includes velocity-weakening friction to spontaneously generate a series of fast frictional instabilities that correspond to analog earthquakes. A match between numerical and laboratory source parameters is obtained when velocity-strengthening is applied in the aseismic regions to stabilize the rupture. Spontaneous evolution of absolute stresses leads to nucleation by coalescence of neighboring patches, mainly occurring at evolving asperities near the seismogenic zone limits. Consequently, a crack-, or occasionally even pulse-like, rupture propagates toward the opposite side of the seismogenic zone by increasing stresses ahead of its rupture front, until it arrests on a barrier. The resulting surface displacements qualitatively agree with geodetic observations and show landward and, from near the downdip limit, upward interseismic motions. These are rebound and reversed coseismically. This slip increases adjacent stresses, which are relaxed postseismically by afterslip and thereby produce persistent seaward motions. The wide range of observed physical phenomena, including back-propagation and repeated slip, and the agreement with laboratory results demonstrate that visco-elasto-plastic geodynamic models with rate-dependent friction form a new tool that can greatly contribute to our understanding of the seismic cycle at subduction zones.

  20. 40 CFR Appendix E to Subpart S of... - Transient Test Driving Cycle

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 2 2010-07-01 2010-07-01 false Transient Test Driving Cycle E Appendix... Driving Cycle (I) Driver's trace. All excursions in the transient driving cycle shall be evaluated by the... shall cause a test to be void. In addition, provisions shall be available to utilize cycle validation...

  1. Sourcing Life Cycle Inventory Data

    Science.gov (United States)

    The collection and validation of quality lifecycle inventory (LCI) data can be the most difficult and time-consuming aspect of developing a life cycle assessment (LCA). Large amounts of process and production data are needed to complete the LCI. For many studies, the LCA analyst ...

  2. A comparison of advanced heat recovery power cycles in a combined cycle for large ships

    International Nuclear Information System (INIS)

    Larsen, Ulrik; Sigthorsson, Oskar; Haglind, Fredrik

    2014-01-01

    Strong motivation exists within the marine sector to reduce fuel expenses and to comply with ever stricter emission regulations. Heat recovery can address both of these issues. The ORC (organic Rankine cycle), the Kalina cycle and the steam Rankine cycle have received the majority of the focus in the literature. In the present work we compare these cycles in a combined cycle application with a large marine two-stroke diesel engine. We present an evaluation of the efficiency and the environmental impact, safety concerns and practical aspects of each of the cycles. A previously validated numerical engine model is combined with a turbocharger model and bottoming cycle models written in Matlab. Genetic algorithm optimisation results suggest that the Kalina cycle possess no significant advantages compared to the ORC or the steam cycle. While contributing to very high efficiencies, the organic working fluids possess high global warming potentials and hazard levels. It is concluded that the ORC has the greatest potential for increasing the fuel efficiency, and the combined cycle offers very high thermal efficiency. While being less efficient, the steam cycle has the advantages of being well proven, harmless to the environment as well as being less hazardous in comparison. - Highlights: • We compare steam, ORC (organic Rankine cycle) and Kalina cycles for waste heat recovery in marine engines. • We evaluate the efficiency and important qualitative differences. • The Kalina cycle presents no apparent advantages. • The steam cycle is well known, harmless and has a high efficiency. • The ORC has the highest efficiency but also important drawbacks

  3. Control por Modos Deslizantes y Planitud Diferencial de un Convertidor de CD/CD Boost: Resultados Experimentales

    Directory of Open Access Journals (Sweden)

    R. Silva-Ortigoza

    2008-10-01

    Full Text Available Resumen: En este trabajo se presenta el control del convertidor de potencia de CD a CD Boost. En este sistema existen dos problemas de control, a saber; la regulación alrededor de un punto de equilibrio y la de seguimiento de trayectoria del voltaje de salida. Nosotros enfocamos nuestra atención al segundo problema de control. Debido a las propiedades de fase que satisface este convertidor, para realizar la tarea de seguimiento de trayectoria se diseña un controlador indirecto basado en modos deslizantes en combinación con planitud diferencial, el cual permite el seguimiento de trayectoria de la variable de fase no mínima (voltaje basado en el seguimiento de trayectoria de la variable de fase mínima (corriente. La síntesis de este controlador se realiza con la ayuda de una tarjeta de adquisición de datos National Instruments™ PCI-6025E junto con el software de aplicación MATLAB®-Simulink®. Se aplica este controlador al prototipo del convertidor Boost desarrollado y se obtienen resultados experimentales satisfactorios. Palabras clave: Control Indirecto, Convertidor de CD/CD Boost, Modos Deslizantes, Planitud Diferencial, Seguimiento de Trayectoria

  4. Web-based turbine cycle performance analysis for nuclear power plants

    International Nuclear Information System (INIS)

    Heo, Gyun Young; Lee, Sung Jin; Chang, Soon Heung; Choi, Seong Soo

    2000-01-01

    As an approach to improve the economical efficiency of operating nuclear power plants, a thermal performance analysis tool for steam turbine cycle has been developed. For the validation and the prediction of the signals used in thermal performance analysis, a few statistical signal processing techniques are integrated. The developed tool provides predicted performance calculation capability that is steady-state wet steam turbine cycle simulation, and measurement performance calculation capability which determines component- and cycle-level performance indexes. Web-based interface with all performance analysis is implemented, so even remote users can achieve performance analysis. Comparing to ASME PTC6 (Performance Test Code 6), the focusing point of the developed tool is historical performance analysis rather than single accurate performance test. The proposed signal processing techniques are validated using actual plant signals, and turbine cycle models are tested by benchmarking with a commercial thermal analysis tool

  5. The carbon cycle in a land surface model: modelling, validation and implementation at a global scale; Cycle du carbone dans un modele de surface continentale: modelisation, validation et mise en oeuvre a l'echelle globale

    Energy Technology Data Exchange (ETDEWEB)

    Gibelin, A.L

    2007-05-15

    ISBA-A-gs is an option of the CNRM land surface model ISBA which allows for the simulation of carbon exchanges between the terrestrial biosphere and the atmosphere. The model was implemented for the first time at the global scale as a stand-alone model. Several global simulations were performed to assess the sensitivity of the turbulent fluxes and Leaf Area Index to a doubling of the CO{sub 2} atmospheric concentration, and to the climate change simulated by the end of the 21. century. In addition, a new option of ISBA, referred to as ISBA-CC, was developed in order to simulate a more detailed ecosystem respiration by separating the autotrophic respiration and the heterotrophic respiration. The vegetation dynamics and the carbon fluxes were validated at a global scale using satellite datasets, and at a local scale using data from 26 sites of the FLUXNET network. All these results show that the model is sufficiently realistic to be coupled with a general circulation model, in order to account for interactions between the terrestrial biosphere, the atmosphere and the carbon cycle. (author)

  6. Thermodynamic control-oriented modeling of cycle-to-cycle exhaust gas temperature in an HCCI engine

    International Nuclear Information System (INIS)

    Dehghani Firoozabadi, M.; Shahbakhti, M.; Koch, C.R.; Jazayeri, S.A.

    2013-01-01

    Highlights: • First thermodynamic model in the literature to predict exhaust temperature in HCCI engines. • The model can be used for integrated control of HCCI combustion and exhaust temperature. • The model is experimentally validated at over 300 steady state and transient conditions. • Results show a good agreement between predicted and measured exhaust temperatures. • Sensitivity of exhaust gas temperature to variation of engine variables is shown. - Abstract: Model-based control of Homogenous Charge Compression Ignition (HCCI) engine exhaust temperature is a viable solution to optimize efficiency of both engine and the exhaust aftertreatment system. Low exhaust temperature in HCCI engines can limit the abatement of hydrocarbon (HC) and carbon monoxide (CO) emissions in an exhaust aftertreatment system. A physical–empirical model is described for control of exhaust temperature in HCCI engines. This model captures cycle-to-cycle dynamics affecting exhaust temperature and is based on thermodynamic relations and semi-empirical correlations. It incorporates intake and exhaust gas flow dynamics, residual gas mixing, and fuel burn rate and is validated with experimental data from a single cylinder engine at over 300 steady state and transient conditions. The validation results indicate a good agreement between predicted and measured exhaust gas temperature

  7. Análisis conductual aplicado en neuropsicología: fundamentos teóricos, experimentales y empíricos.

    Directory of Open Access Journals (Sweden)

    José Alonso Aguilar-Valera

    2016-01-01

    Full Text Available El presente artículo presenta una revisión teórica donde se expone la importancia que tienen los principios y técnicas conductuales dentro del ámbito de la rehabilitación neuropsicológica. En la intervención clínica con pacientes víctimas de disfunción, daño o deterioro neurológico, donde las consecuencias directas sobre el comportamiento son significativas, el uso de las estrategias provenientes de las técnicas de modificación de conducta (conductuales y/o conductual-cognitivas son importantes para el tratamiento de los diversos síndromes neuroconductuales, estando dentro de las competencias del especialista en esta área aplicada de las neurociencias. Además de describirse tanto aspectos teóricos como experimentales de principal relevancia para estos fines, también se mencionarán algunos estudios empíricos llevados a cabo, bajo una metodología de caso único, para una mejor comprensión sobre la utilidad aplicativa de los principios conductuales en el ámbito de la neuropsicología clínica.

  8. Biochemical Validation of the Glyoxylate Cycle in the Cyanobacterium Chlorogloeopsis fritschii Strain PCC 9212.

    Science.gov (United States)

    Zhang, Shuyi; Bryant, Donald A

    2015-05-29

    Cyanobacteria are important photoautotrophic bacteria with extensive but variable metabolic capacities. The existence of the glyoxylate cycle, a variant of the TCA cycle, is still poorly documented in cyanobacteria. Previous studies reported the activities of isocitrate lyase and malate synthase, the key enzymes of the glyoxylate cycle in some cyanobacteria, but other studies concluded that these enzymes are missing. In this study the genes encoding isocitrate lyase and malate synthase from Chlorogloeopsis fritschii PCC 9212 were identified, and the recombinant enzymes were biochemically characterized. Consistent with the presence of the enzymes of the glyoxylate cycle, C. fritschii could assimilate acetate under both light and dark growth conditions. Transcript abundances for isocitrate lyase and malate synthase increased, and C. fritschii grew faster, when the growth medium was supplemented with acetate. Adding acetate to the growth medium also increased the yield of poly-3-hydroxybutyrate. When the genes encoding isocitrate lyase and malate synthase were expressed in Synechococcus sp. PCC 7002, the acetate assimilation capacity of the resulting strain was greater than that of wild type. Database searches showed that the genes for the glyoxylate cycle exist in only a few other cyanobacteria, all of which are able to fix nitrogen. This study demonstrates that the glyoxylate cycle exists in a few cyanobacteria, and that this pathway plays an important role in the assimilation of acetate for growth in one of those organisms. The glyoxylate cycle might play a role in coordinating carbon and nitrogen metabolism under conditions of nitrogen fixation. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

  9. Integral benchmarks with reference to thorium fuel cycle

    International Nuclear Information System (INIS)

    Ganesan, S.

    2003-01-01

    This is a power point presentation about the Indian participation in the CRP 'Evaluated Data for the Thorium-Uranium fuel cycle'. The plans and scope of the Indian participation are to provide selected integral experimental benchmarks for nuclear data validation, including Indian Thorium burn up benchmarks, post-irradiation examination studies, comparison of basic evaluated data files and analysis of selected benchmarks for Th-U fuel cycle

  10. Shift Verification and Validation

    Energy Technology Data Exchange (ETDEWEB)

    Pandya, Tara M. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Evans, Thomas M. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Davidson, Gregory G [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Johnson, Seth R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Godfrey, Andrew T. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2016-09-07

    This documentation outlines the verification and validation of Shift for the Consortium for Advanced Simulation of Light Water Reactors (CASL). Five main types of problems were used for validation: small criticality benchmark problems; full-core reactor benchmarks for light water reactors; fixed-source coupled neutron-photon dosimetry benchmarks; depletion/burnup benchmarks; and full-core reactor performance benchmarks. We compared Shift results to measured data and other simulated Monte Carlo radiation transport code results, and found very good agreement in a variety of comparison measures. These include prediction of critical eigenvalue, radial and axial pin power distributions, rod worth, leakage spectra, and nuclide inventories over a burn cycle. Based on this validation of Shift, we are confident in Shift to provide reference results for CASL benchmarking.

  11. Intelligent Testing of Traffic Light Programs: Validation in Smart Mobility Scenarios

    Directory of Open Access Journals (Sweden)

    Javier Ferrer

    2016-01-01

    Full Text Available In smart cities, the use of intelligent automatic techniques to find efficient cycle programs of traffic lights is becoming an innovative front for traffic flow management. However, this automatic programming of traffic lights requires a validation process of the generated solutions, since they can affect the mobility (and security of millions of citizens. In this paper, we propose a validation strategy based on genetic algorithms and feature models for the automatic generation of different traffic scenarios checking the robustness of traffic light cycle programs. We have concentrated on an extensive urban area in the city of Malaga (in Spain, in which we validate a set of candidate cycle programs generated by means of four optimization algorithms: Particle Swarm Optimization for Traffic Lights, Differential Evolution for Traffic Lights, random search, and Sumo Cycle Program Generator. We can test the cycles of traffic lights considering the different states of the city, weather, congestion, driver expertise, vehicle’s features, and so forth, but prioritizing the most relevant scenarios among a large and varied set of them. The improvement achieved in solution quality is remarkable, especially for CO2 emissions, in which we have obtained a reduction of 126.99% compared with the experts’ solutions.

  12. The glacial cycles and cosmic rays

    CERN Document Server

    Kirkby, Jasper; Müller, R A

    2004-01-01

    The cause of the glacial cycles remains a mystery. The origin is widely accepted to be astronomical since paleoclimatic archives contain strong spectral components that match the frequencies of Earth's orbital modulation. Milankovitch insolation theory contains similar frequencies and has become established as the standard model of the glacial cycles. However, high precision paleoclimatic data have revealed serious discrepancies with the Milankovitch model that fundamentally challenge its validity and re-open the question of what causes the glacial cycles. We propose here that the ice ages are initially driven not by insolation cycles but by cosmic ray changes, probably through their effect on clouds. This conclusion is based on a wide range of evidence, including results presented here on speleothem growth in caves in Austria and Oman, and on a record of cosmic ray flux over the past 220 kyr obtained from the 10Be composition of deep-ocean sediments.

  13. Economic analysis of thorium-uranium fuel cycle introduced into PWRs

    International Nuclear Information System (INIS)

    Fan Li; Sun Qian

    2014-01-01

    Using PWR of Daya Bay Unit l as the reference reactor, a validated computer code was used to calculate the fuel cycle costs for uranium fuel cycle and thorium-uranium fuel cycle over the following 20 0perational years respectively. The calculation results show that the thorium-uranium fuel cycle is economically competitive with the uranium fuel cycle when reprocessing mode is adopted. For thorium-uranium fuel cycle, if the price of natural uranium is higher than 120 $ /pound U_3O_8, the fuel cycle cost of the direct disposal mode is greater than that of the reprocessing mode. Therefore, when the uranium price may maintain a high level long-termly, adopting reprocessing mode will benefit the economic advantage for the thorium-uranium fuel cycle introduced into PWRs. (authors)

  14. The Twin-Cycle Experiential Learning Model: Reconceptualising Kolb's Theory

    Science.gov (United States)

    Bergsteiner, Harald; Avery, Gayle C.

    2014-01-01

    Experiential learning styles remain popular despite criticisms about their validity, usefulness, fragmentation and poor definitions and categorisation. After examining four prominent models and building on Bergsteiner, Avery, and Neumann's suggestion of a dual cycle, this paper proposes a twin-cycle experiential learning model to overcome…

  15. Audit of Major Defense Acquisition Programs Cycle Time

    National Research Council Canada - National Science Library

    Ugone, Mary

    2001-01-01

    ... (GPRA) as indicated in the FY 2000 Annual Report of the Secretary of Defense. Specifically, we assessed whether the process and factors, used to establish the metric goal of MDAP cycle time, were valid...

  16. Sodium fast reactors with closed fuel cycle

    CERN Document Server

    Raj, Baldev; Vasudeva Rao, PR 0

    2015-01-01

    Sodium Fast Reactors with Closed Fuel Cycle delivers a detailed discussion of an important technology that is being harnessed for commercial energy production in many parts of the world. Presenting the state of the art of sodium-cooled fast reactors with closed fuel cycles, this book:Offers in-depth coverage of reactor physics, materials, design, safety analysis, validations, engineering, construction, and commissioning aspectsFeatures a special chapter on allied sciences to highlight advanced reactor core materials, specialized manufacturing technologies, chemical sensors, in-service inspecti

  17. Addressing the effect of social life cycle assessments

    DEFF Research Database (Denmark)

    Jørgensen, Andreas; Dreyer, Louise Camilla; Wangel, Arne

    2012-01-01

    the validity of these hypotheses. Results: Three in some cases potentially overlapping SLCA approaches are presented, assumed to create a beneficial effect in the life cycle in different ways. However, empirical and theoretical findings show that the beneficial effects proposed to arise from the use of each......Purpose: In the recently published ‘Guidelines for social life cycle assessment of products’, it is stated that the ultimate objective of developing the social life cycle assessment (SLCA) is to promote improvements of social conditions for the stakeholders in the life cycle. This article addresses...... how the SLCA should be developed so that its use promotes these improvements. Methods: Hypotheses of how the use of SLCA can promote improvement of social conditions in the life cycle are formulated, after which theories and empirical findings from relevant fields of research are used to address...

  18. Experimental study of the mechanisms of CO{sub 2} capture by calcium cycle under circulating fluidized bed conditions; Etude experimentale des mecanismes de capture du CO{sub 2} par cycle calcium en lit fluidise circulant

    Energy Technology Data Exchange (ETDEWEB)

    Hoteit, A

    2006-06-15

    The work undertaken in this Thesis in partnership with department R and D of ALSTOM Power Boilers, CEMEX and the ADEME, relates to the experimental study of various phenomena associated to CO{sub 2} capture under circulating fluidized bed conditions. The size of particles, temperature and the CO{sub 2} concentration have an influence on the limestone calcination reaction. The reaction of carbonation of lime is not total. During successive cycles of calcination/carbonation, the rate of carbonation obtained with hydrated lime is increasingly higher than that obtained with the lime. Under continuously reducing conditions, the decomposition of sulphates present in the bed ashes is not total. This decomposition is total under reduction/oxidation cycles. A modeling of calcination allowed to determine the intrinsic kinetic constants of calcination and carbonation. (author)

  19. Cycle analysis of MCFC/gas turbine system

    Directory of Open Access Journals (Sweden)

    Musa Abdullatif

    2017-01-01

    Full Text Available High temperature fuel cells such as the solid oxide fuel cell (SOFC and the molten carbonate fuel cell (MCFC are considered extremely suitable for electrical power plant application. The molten carbonate fuel cell (MCFC performances is evaluated using validated model for the internally reformed (IR fuel cell. This model is integrated in Aspen Plus™. Therefore, several MCFC/Gas Turbine systems are introduced and investigated. One of this a new cycle is called a heat recovery (HR cycle. In the HR cycle, a regenerator is used to preheat water by outlet air compressor. So the waste heat of the outlet air compressor and the exhaust gases of turbine are recovered and used to produce steam. This steam is injected in the gas turbine, resulting in a high specific power and a high thermal efficiency. The cycles are simulated in order to evaluate and compare their performances. Moreover, the effects of an important parameters such as the ambient air temperature on the cycle performance are evaluated. The simulation results show that the HR cycle has high efficiency.

  20. Cycle analysis of MCFC/gas turbine system

    Science.gov (United States)

    Musa, Abdullatif; Alaktiwi, Abdulsalam; Talbi, Mosbah

    2017-11-01

    High temperature fuel cells such as the solid oxide fuel cell (SOFC) and the molten carbonate fuel cell (MCFC) are considered extremely suitable for electrical power plant application. The molten carbonate fuel cell (MCFC) performances is evaluated using validated model for the internally reformed (IR) fuel cell. This model is integrated in Aspen Plus™. Therefore, several MCFC/Gas Turbine systems are introduced and investigated. One of this a new cycle is called a heat recovery (HR) cycle. In the HR cycle, a regenerator is used to preheat water by outlet air compressor. So the waste heat of the outlet air compressor and the exhaust gases of turbine are recovered and used to produce steam. This steam is injected in the gas turbine, resulting in a high specific power and a high thermal efficiency. The cycles are simulated in order to evaluate and compare their performances. Moreover, the effects of an important parameters such as the ambient air temperature on the cycle performance are evaluated. The simulation results show that the HR cycle has high efficiency.

  1. Proteomic Analysis of the Cell Cycle of Procylic Form Trypanosoma brucei.

    Science.gov (United States)

    Crozier, Thomas W M; Tinti, Michele; Wheeler, Richard J; Ly, Tony; Ferguson, Michael A J; Lamond, Angus I

    2018-06-01

    We describe a single-step centrifugal elutriation method to produce synchronous Gap1 (G1)-phase procyclic trypanosomes at a scale amenable for proteomic analysis of the cell cycle. Using ten-plex tandem mass tag (TMT) labeling and mass spectrometry (MS)-based proteomics technology, the expression levels of 5325 proteins were quantified across the cell cycle in this parasite. Of these, 384 proteins were classified as cell-cycle regulated and subdivided into nine clusters with distinct temporal regulation. These groups included many known cell cycle regulators in trypanosomes, which validates the approach. In addition, we identify 40 novel cell cycle regulated proteins that are essential for trypanosome survival and thus represent potential future drug targets for the prevention of trypanosomiasis. Through cross-comparison to the TrypTag endogenous tagging microscopy database, we were able to validate the cell-cycle regulated patterns of expression for many of the proteins of unknown function detected in our proteomic analysis. A convenient interface to access and interrogate these data is also presented, providing a useful resource for the scientific community. Data are available via ProteomeXchange with identifier PXD008741 (https://www.ebi.ac.uk/pride/archive/). © 2018 by The American Society for Biochemistry and Molecular Biology, Inc.

  2. Theoretical interpretations and experimental verifications of a radioelectric resonance method for measuring the electronic density and collision frequency in a discharge plasma in gases; Interpretations theoriques et verifications experimentales d'une methode de resonance radioelectrique pour la mesure de la densite d'une decharge dans les gaz

    Energy Technology Data Exchange (ETDEWEB)

    Nguyen Trong, Khoi [Commissariat a l' Energie Atomique, Saclay (France).Centre d' Etudes Nucleaires

    1960-07-01

    Theoretical discussions and experimental verifications of one radioelectric resonance method for measuring plasma electronic density and collision frequency. (author) [French] Discussions theoriques et verifications experimentales sur une methode de resonance radioelectrique pour la mesure de la densite electronique et de la frequence de collision d'un plasma d'une decharge dans le gaz. (auteur)

  3. Integrated Process Modeling-A Process Validation Life Cycle Companion.

    Science.gov (United States)

    Zahel, Thomas; Hauer, Stefan; Mueller, Eric M; Murphy, Patrick; Abad, Sandra; Vasilieva, Elena; Maurer, Daniel; Brocard, Cécile; Reinisch, Daniela; Sagmeister, Patrick; Herwig, Christoph

    2017-10-17

    During the regulatory requested process validation of pharmaceutical manufacturing processes, companies aim to identify, control, and continuously monitor process variation and its impact on critical quality attributes (CQAs) of the final product. It is difficult to directly connect the impact of single process parameters (PPs) to final product CQAs, especially in biopharmaceutical process development and production, where multiple unit operations are stacked together and interact with each other. Therefore, we want to present the application of Monte Carlo (MC) simulation using an integrated process model (IPM) that enables estimation of process capability even in early stages of process validation. Once the IPM is established, its capability in risk and criticality assessment is furthermore demonstrated. IPMs can be used to enable holistic production control strategies that take interactions of process parameters of multiple unit operations into account. Moreover, IPMs can be trained with development data, refined with qualification runs, and maintained with routine manufacturing data which underlines the lifecycle concept. These applications will be shown by means of a process characterization study recently conducted at a world-leading contract manufacturing organization (CMO). The new IPM methodology therefore allows anticipation of out of specification (OOS) events, identify critical process parameters, and take risk-based decisions on counteractions that increase process robustness and decrease the likelihood of OOS events.

  4. External validation and calibration of IVFpredict: a national prospective cohort study of 130,960 in vitro fertilisation cycles.

    Directory of Open Access Journals (Sweden)

    Andrew D A C Smith

    Full Text Available Accurately predicting the probability of a live birth after in vitro fertilisation (IVF is important for patients, healthcare providers and policy makers. Two prediction models (Templeton and IVFpredict have been previously developed from UK data and are widely used internationally. The more recent of these, IVFpredict, was shown to have greater predictive power in the development dataset. The aim of this study was external validation of the two models and comparison of their predictive ability.130,960 IVF cycles undertaken in the UK in 2008-2010 were used to validate and compare the Templeton and IVFpredict models. Discriminatory power was calculated using the area under the receiver-operator curve and calibration assessed using a calibration plot and Hosmer-Lemeshow statistic. The scaled modified Brier score, with measures of reliability and resolution, were calculated to assess overall accuracy. Both models were compared after updating for current live birth rates to ensure that the average observed and predicted live birth rates were equal. The discriminative power of both methods was comparable: the area under the receiver-operator curve was 0.628 (95% confidence interval (CI: 0.625-0.631 for IVFpredict and 0.616 (95% CI: 0.613-0.620 for the Templeton model. IVFpredict had markedly better calibration and higher diagnostic accuracy, with calibration plot intercept of 0.040 (95% CI: 0.017-0.063 and slope of 0.932 (95% CI: 0.839-1.025 compared with 0.080 (95% CI: 0.044-0.117 and 1.419 (95% CI: 1.149-1.690 for the Templeton model. Both models underestimated the live birth rate, but this was particularly marked in the Templeton model. Updating the models to reflect improvements in live birth rates since the models were developed enhanced their performance, but IVFpredict remained superior.External validation in a large population cohort confirms IVFpredict has superior discrimination and calibration for informing patients, clinicians and

  5. Relation between Feynman Cycles and Off-Diagonal Long-Range Order

    International Nuclear Information System (INIS)

    Ueltschi, Daniel

    2006-01-01

    The usual order parameter for Bose-Einstein condensation involves the off-diagonal correlation function of Penrose and Onsager, but an alternative is Feynman's notion of infinite cycles. We present a formula that relates both order parameters. We discuss its validity with the help of rigorous results and heuristic arguments. The conclusion is that infinite cycles do not always represent the Bose condensate

  6. Verification and Validation in Systems Engineering

    CERN Document Server

    Debbabi, Mourad; Jarraya, Yosr; Soeanu, Andrei; Alawneh, Luay

    2010-01-01

    "Verification and validation" represents an important process used for the quality assessment of engineered systems and their compliance with the requirements established at the beginning of or during the development cycle. Debbabi and his coauthors investigate methodologies and techniques that can be employed for the automatic verification and validation of systems engineering design models expressed in standardized modeling languages. Their presentation includes a bird's eye view of the most prominent modeling languages for software and systems engineering, namely the Unified Model

  7. Validation of Simulation Codes for Future Systems: Motivations, Approach and the Role of Nuclear Data

    International Nuclear Information System (INIS)

    G. Palmiotti; M. Salvatores; G. Aliberti

    2007-01-01

    The validation of advanced simulation tools will still play a very significant role in several areas of reactor system analysis. This is the case of reactor physics and neutronics, where nuclear data uncertainties still play a crucial role for many core and fuel cycle parameters. The present paper gives a summary of validation motivations, objectives and approach. A validation effort is in particular necessary in the frame of advanced (e.g. Generation-IV or GNEP) reactors and associated fuel cycles assessment and design

  8. Defining the baseline in social life cycle assessment

    DEFF Research Database (Denmark)

    Jørgensen, Andreas; Finkbeiner, Matthias; Jørgensen, Michael Søgaard

    2010-01-01

    A relatively broad consensus has formed that the purpose of developing and using the social life cycle assessment (SLCA) is to improve the social conditions for the stakeholders affected by the assessed product's life cycle. To create this effect, the SLCA, among other things, needs to provide...... valid assessments of the consequence of the decision that it is to support. The consequence of a decision to implement a life cycle of a product can be seen as the difference between the decision being implemented and 'non-implemented' product life cycle. This difference can to some extent be found...... using the consequential environmental life cycle assessment (ELCA) methodology to identify the processes that change as a consequence of the decision. However, if social impacts are understood as certain changes in the lives of the stakeholders, then social impacts are not only related to product life...

  9. Contacto normal entre un medio elasto-plástico continuo y una esfera rígida : observaciones experimentales y computacionales

    Directory of Open Access Journals (Sweden)

    Ángela María Pedraza

    2005-01-01

    Full Text Available Se presenta en este trabajo una investigación experimental y numérica del contacto normal de una esfera rígida con una placa plana de material cuyo comportamiento mecánico se asume de tipo elasto-plástico. Los esfuerzos locales bajo el punto de contacto se han obtenido experimentalmente mediante visualización foto-elástica. Se ha evaluado numéricamente la evolución de los bulbos de esfuerzo bajo el punto contacto como función del tiempo y se ha efectuado la comparación con las observaciones experimentales. Los resultados indican que un modelo elasto-plástico tridimensional reproduce de manera apropiada las características principales observadas en los experimentos físicos. Este ejercicio puramente académico y de carácter didáctico enfatiza en el enorme potencial de los elementos finitos en la solución de problemas de deformación bajo diferentes tipos de modelos constitutivos y pone de manifiesto la enorme utilidad del modelamiento matemático y computacional basado en aproximaciones continuas de la materia

  10. Análisis de Sistemas Experimentales de Integración Peces-Pollos.

    Directory of Open Access Journals (Sweden)

    Roberto Trejo Albarrán

    2012-02-01

    Full Text Available In this work the objective was to evaluate four treatments using dung of different kinds from experimental cultures, estimating their efficiency in relation to pisciculture production and the characteristics of each pond. The work was carried out in the Laboratorio de Hidrobiología of the Universidad Autónoma del Estado de Morelos (UAEM in Cuernavaca, Morelos, Mexico, in fiberglass ponds with albinotic Oreochromis niloticus. Analysis was made of plankton, as well as bacteriological, dietectic and piscicultural growth and the physical chemistry of water. Fresh chicken excrement showed variations in the amount of nutriments. Abundance of phytoplankton was from 17,008 to 70,080 org/ml. The most abundant was Closterium sp. In zooplankton, total abundance was from 302 to 1,706 org/ml. The dominant zooplankton was Moina sp. with a yield from 22 to 117 g/m2/ 6 months. Considering these findings, it was observed that the digested chicken dung was the most efficient of the four. Pathogenic enterobacteria were always present. En este trabajo, el objetivo fue evaluar cuatro tratamientos utilizando estiércoles de diferentes tipos en cultivos experimentales, estimando su eficiencia en relación a la producción piscícola y las características de cada estanque. Se llevó a cabo en el Laboratorio de Hidrobiología de la UAEM en Cuernavaca, Morelos, México; en estanques de fibra de vidrio, con Oreochromis niloticus albina. Se realizaron análisis del plancton, bacteriológicos, bromatológicos, crecimiento piscícola y fisicoquímicos del agua. Las excretas frescas de pollo presentaron variaciones en la cantidad de nutrimentos. Las abundancias de fitoplancton fueron de 17,008 a 70,080 org/ml. Los más abundantes fueron Closterium sp. En el zooplancton, las abundancias totales fueron de 302 a 1,706 org/ml. El dominante fue Moina sp. El rendimiento fue de 22 a 117 g/m2/6 meses. Considerando lo anterior se observó que la gallinaza digerida fue el esti

  11. Medical application and clinical validation for reliable and trustworthy physiological monitoring using functional textiles: experience from the HeartCycle and MyHeart project.

    Science.gov (United States)

    Reiter, Harald; Muehlsteff, Jens; Sipilä, Auli

    2011-01-01

    Functional textiles are seen as promising technology to enable healthcare services and medical care outside hospitals due to their ability to integrate textile-based sensing and monitoring technologies into the daily life. In the past much effort has been spent onto basic functional textile research already showing that reliable monitoring solutions can be realized. The challenge remains to find and develop suited medical application and to fulfil the boundary conditions for medical endorsement and exploitation. The HeartCycle vest described in this abstract will serve as an example for a functional textile carefully developed according to the requirements of a specific medical application, its clinical validation, the related certification aspects and the next improvement steps towards exploitation.

  12. Effect of LEO cycling on 125 Ah advanced design IPV nickel-hydrogen flight cells - An update

    Science.gov (United States)

    Smithrick, John J.; Hall, Stephen W.

    1991-01-01

    An update of validation test results confirming the breakthrough in LEO cycle life of nickel-hydrogen cells containing 26 percent potassium hydroxide (KOH) electrolyte is presented. A breakthrough in the LEO cycle life of individual pressure vessel nickel-hydrogen cells is reported. The cycle life of boiler plate cells containing 26 percent KOH electrolyte was about 40,000 LEO cycles compared to 3500 cycles for cells containing 31 percent KOH.

  13. Effect of KOH concentration on LEO cycle life of IPV nickel-hydrogen flight cells. An update

    Science.gov (United States)

    Smithrick, John J.; Hall, Stephen W.

    1991-01-01

    An update of validation test results confirming the breakthrough in LEO cycle life of nickel-hydrogen cells containing 26 percent potassium hydroxide (KOH) electrolyte is presented. A breakthrough in the LEO cycle life of individual pressure vessel nickel-hydrogen cells is reported. The cycle life of boiler plate cells containing 26 percent KOH electrolyte was about 40,000 LEO cycles compared to 3500 cycles for cells containing 31 percent KOH.

  14. Effect of KOH concentration on LEO cycle life of IPV nickel-hydrogen flight cells - An update

    Science.gov (United States)

    Smithrick, John J.; Hall, Stephen W.

    1991-01-01

    An update of validation test results confirming the breakthrough in LEO cycle life of nickel-hydrogen cells containing 26 percent potassium hydroxide (KOH) electrolyte is presented. A breakthrough in the LEO cycle life of individual pressure vessel nickel-hydrogen cells is reported. The cycle life of boiler plate cells containing 26 percent KOH electrolyte was about 40,000 LEO cycles compared to 3500 cycles for cells containing 31 percent KOH.

  15. 40 CFR 1065.512 - Duty cycle generation.

    Science.gov (United States)

    2010-07-01

    ... at least 5 Hz. Use these recorded values to calculate cycle-validation statistics and total work. (d... sequence of paired values for speed and torque or for speed and power. (b) Transform normalized values of... describes how to transform these normalized values into a sequence of reference speeds, f nref. Running duty...

  16. RNA-Seq analysis validates the use of culture-derived Trypanosoma brucei and provides new markers for mammalian and insect life-cycle stages.

    Science.gov (United States)

    Naguleswaran, Arunasalam; Doiron, Nicholas; Roditi, Isabel

    2018-04-02

    Trypanosoma brucei brucei, the parasite causing Nagana in domestic animals, is closely related to the parasites causing sleeping sickness, but does not infect humans. In addition to its importance as a pathogen, the relative ease of genetic manipulation and an innate capacity for RNAi extend its use as a model organism in cell and infection biology. During its development in its mammalian and insect (tsetse fly) hosts, T. b. brucei passes through several different life-cycle stages. There are currently four life-cycle stages that can be cultured: slender forms and stumpy forms, which are equivalent to forms found in the mammal, and early and late procyclic forms, which are equivalent to forms in the tsetse midgut. Early procyclic forms show coordinated group movement (social motility) on semi-solid surfaces, whereas late procyclic forms do not. RNA-Seq was performed on biological replicates of each life-cycle stage. These constitute the first datasets for culture-derived slender and stumpy bloodstream forms and early and late procyclic forms. Expression profiles confirmed that genes known to be stage-regulated in the animal and insect hosts were also regulated in culture. Sequence reads of 100-125 bases provided sufficient precision to uncover differential expression of closely related genes. More than 100 transcripts showed peak expression in stumpy forms, including adenylate cyclases and several components of inositol metabolism. Early and late procyclic forms showed differential expression of 73 transcripts, a number of which encoded proteins that were previously shown to be stage-regulated. Moreover, two adenylate cyclases previously shown to reduce social motility are up-regulated in late procyclic forms. This study validates the use of cultured bloodstream forms as alternatives to animal-derived parasites and yields new markers for all four stages. In addition to underpinning recent findings that early and late procyclic forms are distinct life-cycle stages

  17. Western Canada drilling cycle optimization

    International Nuclear Information System (INIS)

    2003-06-01

    The oil and gas industry in western Canada operates in annual and seasonal cycles with peak activity periods that require a large skilled labour force for short periods of time. This study examines why seismic and drilling activity is greatest during the first quarter of the year instead of being distributed evenly over the year. The objective of the study was to provide recommendations that would help optimize the industry cycle. The study includes an analysis of historical trends that validate the industry first quarter peaking activity. It also includes interviews with 36 industry representatives and provides insight and validation of trends. The final phase of the report includes recommendations that both industry and governments may wish to implement. The study includes financial, operational and environmental considerations. It was shown that natural gas directed drilling activity is strongly correlated with changes in natural gas prices. In the case of oil drilling activity, peak activity responds to oil prices from the prior quarter. In general, drilling and seismic costs are higher in the winter months because of increased demand for equipment and services. In addition winter drilling operations require a diesel fired boiler to generate steam. 36 refs., 2 tabs., 52 figs

  18. The development and validation of a three-tier diagnostic test measuring pre-service elementary education and secondary science teachers' understanding of the water cycle

    Science.gov (United States)

    Schaffer, Dannah Lynn

    The main goal of this research study was to develop and validate a three-tier diagnostic test to determine pre-service teachers' (PSTs) conceptual knowledge of the water cycle. For a three-tier diagnostic test, the first tier assesses content knowledge; in the second tier, a reason is selected for the content answer; and the third tier allows test-takers to select how confident they are in their answers for the first two tiers. The second goal of this study was to diagnose any alternative conceptions PSTs might have about the water cycle. The Water Cycle Diagnostic Test (WCDT) was developed using the theoretical framework by Treagust (1986, 1988, and 1995), and in similar studies that developed diagnostic tests (e.g., Calean & Subramaniam, 2010a; Odom & Barrow, 2007; Pesman & Eryilmaz, 2010). The final instrument consisted of 15 items along with a demographic survey that examined PSTs' weather-related experiences that may or may not have affected the PSTs' understanding of the water cycle. The WCDT was administered to 77 PSTs enrolled in science methods courses during the fall of 2012. Among the 77 participants, 37 of the PSTs were enrolled in elementary education (EPST) and 40 in secondary science (SPST). Using exploratory factor analysis, five categories were factored out for the WCDT: Phase Change of Water; Condensation and Storage; Clouds; Global Climate Change; and Movement through the Water Cycle. Analysis of the PSTs' responses demonstrated acceptable reliability (alpha = 0.62) for the instrument, and acceptable difficulty indices and discrimination indices for 12 of the items. Analysis indicated that the majority of the PSTs had a limited understanding of the water cycle. Of the PSTs sampled, SPSTs were significantly more confident in their answers' on the WCDT than the EPSTs. Completion of an undergraduate atmospheric science and/or meteorology course, as well as a higher interest in listening and/or viewing weather-related programs, resulted in PSTs

  19. Equilibrium transuranic management scheme for diverse fuel cycle analysis

    International Nuclear Information System (INIS)

    Haas, Jason; Lee, John C.

    2008-01-01

    A key issue cited in the U.S. Department of Energy's report to Congress (2003) on the research path for the Advanced Fuel Cycle Initiative (AFCI) is an accurate estimation of life cycle costs for the construction, operation, decontamination and decommissioning of all fuel cycle facilities. In this report we discuss the methodology and validation of a fuel cycle model based on equilibrium operation. We apply our model to a diverse set of advanced reactors and fuel types in order to determine the most effective transmuting system while simultaneously minimizing fuel cycle costs. Our analysis shows that a nearly instant equilibrium modeling of fuel cycle scenarios can accurately approximate the detailed complex dynamic models developed by national laboratories. Our analysis also shows that the cost of transmuting Spent Nuclear Fuel (SNF) from a UO 2 fueled Pressurized Water Reactor (PWR) is minimized by utilizing the thorium cycle in sodium cooled fast reactors and is near the cost for long term repository storage of SNF at Yucca Mountain. (authors)

  20. Learning, Unlearning and Relearning--Knowledge Life Cycles in Library and Information Science Education

    Science.gov (United States)

    Bedford, Denise A. D.

    2015-01-01

    The knowledge life cycle is applied to two core capabilities of library and information science (LIS) education--teaching, and research and development. The knowledge claim validation, invalidation and integration steps of the knowledge life cycle are translated to learning, unlearning and relearning processes. Mixed methods are used to determine…

  1. Analytical method development and validation for quantification of uranium in compounds of the nuclear fuel cycle by Fourier Transform Infrared (FTIR) Spectroscopy

    International Nuclear Information System (INIS)

    Pereira, Elaine

    2016-01-01

    This work presents a low cost, simple and new methodology for direct quantification of uranium in compounds of the nuclear fuel cycle, based on Fourier Transform Infrared (FTIR) spectroscopy using KBr pressed discs technique. Uranium in different matrices were used to development and validation: UO 2 (NO 3 )2.2TBP complex (TBP uranyl nitrate complex) in organic phase and uranyl nitrate (UO 2 (NO 3 ) 2 ) in aqueous phase. The parameters used in the validation process were: linearity, selectivity, accuracy, limits of detection (LD) and quantitation (LQ), precision (repeatability and intermediate precision) and robustness. The method for uranium in organic phase (UO 2 (NO 3 )2.2TBP complex in hexane/embedded in KBr) was linear (r = 0.9980) over the range of 0.20% 2.85% U/ KBr disc, LD 0.02% and LQ 0.03%, accurate (recoveries were over 101.0%), robust and precise (RSD < 1.6%). The method for uranium aqueous phase (UO 2 (NO 3 ) 2 /embedded in KBr) was linear (r = 0.9900) over the range of 0.14% 1.29% U/KBr disc, LD 0.01% and LQ 0.02%, accurate (recoveries were over 99.4%), robust and precise (RSD < 1.6%). Some process samples were analyzed in FTIR and compared with gravimetric and X-ray fluorescence (XRF) analyses showing similar results in all three methods. The statistical tests (t-Student and Fischer) showed that the techniques are equivalent. The validated method can be successfully employed for routine quality control analysis for nuclear compounds. (author)

  2. PENGEMBANGAN PERANGKAT PEMBELAJARAN IPA MODEL LEARNING CYCLE 7E UNTUK MENINGKATKAN KEMAMPUAN BERPIKIR KRITIS

    Directory of Open Access Journals (Sweden)

    Fembriani -

    2015-08-01

    Full Text Available Proses pembelajaran dalam KTSP memerlukan pengembangan perangkat pembelajaran. Observasi yang peneliti lakukan di kelas IV pada lima sekolah dasar, 80% guru tidak membuat perangkat pembelajaran sendiri, 60% SD masih menggunakan perangkat pembelajaran teacher center, dan 50% belum mengembangkan perangkat pembelajaran untuk meningkatkan kemampuan berpikir kritis yang sesuai dengan indikator. Penelitian ini menggunakan model pengembangan Plomp dengan tujuan untuk memperoleh perangkat pembelajaran yang valid, efektif, dan praktis. Hasil Penelitian menunjukan: (1 pengembangan perangkat pembelajaran learning cycle 7E menghasilkan perangkat pembelajaran yang valid. Skor rata-rata validasi ahli terhadap silabus 3,6 (sangat baik, RPP 3,7 (sangat baik, bahan ajar 3,5 (sangat baik, LKS 3,6 (sangat baik, dan evaluasi  3,5 (sangat baik. (2 implementasi perangkat  pembelajaran yang valid terbukti efektif karena setelah diberi perlakuan menggunakan model learning cycle 7E terdapat perbedaan antara kelas kontrol dan ekperimen dengan nilai signifikansi 0,02 < 0,05 dan peningkatan hasil N-gain kelas eksperimen sebesar 0,62 yang menunjukan kriteria sedang. (3 Berdasarkan analisis kuisioner, perangkat pembelajaran yang  praktis dapat diterima oleh siswa dan guru sebesar 80% dan 80%. Simpulan yang diperoleh dari penelitian ini adalah pengembangan perangkat pembelajaran IPA model learning cycle 7E adalah valid, efektif, dan praktis.The learning process in school based curiculum requires the development of learning instrument. The observation that researcher done on fourth grade at five Elementary Schools, 80% of teachers do not make their own learning device, 60% of  school teachers still use the teacher learning center, and 50% have not yet developed learning tools to improve critical thinking skills in accordance with the indicators. This study use a model of development Plomp in order to obtain a valid learning device, effective, and practical. The result of

  3. Model-based verification and validation of the SMAP uplink processes

    Science.gov (United States)

    Khan, M. O.; Dubos, G. F.; Tirona, J.; Standley, S.

    Model-Based Systems Engineering (MBSE) is being used increasingly within the spacecraft design community because of its benefits when compared to document-based approaches. As the complexity of projects expands dramatically with continually increasing computational power and technology infusion, the time and effort needed for verification and validation (V& V) increases geometrically. Using simulation to perform design validation with system-level models earlier in the life cycle stands to bridge the gap between design of the system (based on system-level requirements) and verifying those requirements/validating the system as a whole. This case study stands as an example of how a project can validate a system-level design earlier in the project life cycle than traditional V& V processes by using simulation on a system model. Specifically, this paper describes how simulation was added to a system model of the Soil Moisture Active-Passive (SMAP) mission's uplink process. Also discussed are the advantages and disadvantages of the methods employed and the lessons learned; which are intended to benefit future model-based and simulation-based development efforts.

  4. New criteria on the existence of stable-limit cycles

    Energy Technology Data Exchange (ETDEWEB)

    Gonzales-Gascon, F [Instituto de Estructura de la Materia (GIFT) y Dep. de Fisica Teorica Universidad Complutense, Madrid (Espana); Kumpera, A [Universidade Estadual de Campinas (Brazil). Inst. de Matematica

    1978-06-10

    Negative criteria are given assuring the absence of stable limit cycles. These criteria are valid for vector fields over R/sup 3/ and R/sup 4/ and some of them can be applied to vector fields over Rsup(n).

  5. Optimization of preventive maintenance cycle based on experimental feedback in nuclear power plants

    International Nuclear Information System (INIS)

    Shi Jie

    2010-01-01

    The preventive replacement method based on the experimental feedback was introduced. In this method, the initial preventive replacement cycle was acquired by expert votes. The preventive replacement cycle combined with the operation experience of the equipment was gained by means of Bayesian theorem. The Optimized preventive replacement cycle can be acquired by comparing the two probabilities that no fault occurs within the cycle. This method was tested on the switches which were used in Daya Bay Nuclear Power Plant and the results indicated its validity. (authors)

  6. Validation test of advanced technology for IPV nickel-hydrogen flight cells: Update

    Science.gov (United States)

    Smithrick, John J.; Hall, Stephen W.

    1992-01-01

    Individual pressure vessel (IPV) nickel-hydrogen technology was advanced at NASA Lewis and under Lewis contracts with the intention of improving cycle life and performance. One advancement was to use 26 percent potassium hydroxide (KOH) electrolyte to improve cycle life. Another advancement was to modify the state-of-the-art cell design to eliminate identified failure modes. The modified design is referred to as the advanced design. A breakthrough in the low-earth-orbit (LEO) cycle life of IPV nickel-hydrogen cells has been previously reported. The cycle life of boiler plate cells containing 26 percent KOH electrolyte was about 40,000 LEO cycles compared to 3,500 cycles for cells containing 31 percent KOH. The boiler plate test results are in the process of being validated using flight hardware and real time LEO testing at the Naval Weapons Support Center (NWSC), Crane, Indiana under a NASA Lewis Contract. An advanced 125 Ah IPV nickel-hydrogen cell was designed. The primary function of the advanced cell is to store and deliver energy for long-term, LEO spacecraft missions. The new features of this design are: (1) use of 26 percent rather than 31 percent KOH electrolyte; (2) use of a patented catalyzed wall wick; (3) use of serrated-edge separators to facilitate gaseous oxygen and hydrogen flow within the cell, while still maintaining physical contact with the wall wick for electrolyte management; and (4) use of a floating rather than a fixed stack (state-of-the-art) to accommodate nickel electrode expansion due to charge/discharge cycling. The significant improvements resulting from these innovations are: extended cycle life; enhanced thermal, electrolyte, and oxygen management; and accommodation of nickel electrode expansion. The advanced cell design is in the process of being validated using real time LEO cycle life testing of NWSC, Crane, Indiana. An update of validation test results confirming this technology is presented.

  7. GNPS 18-months fuel cycles core thermal hydraulic design

    International Nuclear Information System (INIS)

    Liu Changwen; Zhou Zhou

    2002-01-01

    GNPS begins to implement the 18-month fuel cycles from the initial annual reload at cycle 9, thus the initial core thermal hydraulic design is not valid any more. The new critical heat flux (CHF) correlation, FC, which is developed by Framatome, is used in the design, and the generalized statistical methodology (GSM) instead of the initial deterministic methodology is used to determine the DNBR design limit. As the AFA 2G and AFA 3G are mixed loaded in the transition cycle, it will result that the minimum DNBR in the mixed core is less than that of AFA 3G homogenous core, the envelop mixed core DNBR penalty is given. Consequently the core physical limit for mixed core and equilibrium cycles, and the new over temperature ΔT overpower ΔT are determined

  8. Optimal design of solid oxide fuel cell, ammonia-water single effect absorption cycle and Rankine steam cycle hybrid system

    Science.gov (United States)

    Mehrpooya, Mehdi; Dehghani, Hossein; Ali Moosavian, S. M.

    2016-02-01

    A combined system containing solid oxide fuel cell-gas turbine power plant, Rankine steam cycle and ammonia-water absorption refrigeration system is introduced and analyzed. In this process, power, heat and cooling are produced. Energy and exergy analyses along with the economic factors are used to distinguish optimum operating point of the system. The developed electrochemical model of the fuel cell is validated with experimental results. Thermodynamic package and main parameters of the absorption refrigeration system are validated. The power output of the system is 500 kW. An optimization problem is defined in order to finding the optimal operating point. Decision variables are current density, temperature of the exhaust gases from the boiler, steam turbine pressure (high and medium), generator temperature and consumed cooling water. Results indicate that electrical efficiency of the combined system is 62.4% (LHV). Produced refrigeration (at -10 °C) and heat recovery are 101 kW and 22.1 kW respectively. Investment cost for the combined system (without absorption cycle) is about 2917 kW-1.

  9. Developing the Social Life Cycle Assessment

    DEFF Research Database (Denmark)

    Jørgensen, Andreas

    social audits. Through an interview with a social auditor it is suggested that the auditor varies the procedures for carrying out the audit in order to get the most valid result. For example, the auditor has to take into account the various tricks a company in a given context normally uses to cheat......This thesis seeks to add to the development of the Social Life Cycle Assessment (SLCA), which can be defined as an assessment method for assessing the social impacts connected to the life cycle of a product, service or system. In such development it is important to realise that the SLCA is only...... appealing to the extent that it does what it is supposed to do. In this thesis, this goal of SLCA is defined as to support improvements of the social conditions for the stakeholders throughout the life cycle of the assessed product, system or service. This effect should arise through decision makers...

  10. Evaluación de programas bilingües: análisis de resultados de las secciones experimentales de francés en el marco del Plan de Fomento del Plurilingúismo de Andalucía

    OpenAIRE

    Pérez Invernón, María América

    2013-01-01

    Evaluación de programas bilingües: Análisis de resultados de las secciones experimentales de francés en el marco del Plan de Fomento del plurilingüismo de Andalucía¿ En 1999 llega la implantación de forma experimental del futuro Plan de Fomento del Plurilingüismo de Andalucía. A finales del curso 2008/09 algunos de los alumnos/as que comenzaron en aquel entonces finalizaron el recorrido formativo en esta sección junto con aquellos otros compañeros que se habían querido incorporar en distin...

  11. Presencia de la roya naranja Puccinia kuehnii (Krüger) Butler en áreas experimentales de caña de azúcar (Sacharum spp. híbrido) de la región central de Cuba

    OpenAIRE

    Aday Díaz, Osmany; Barroso Medina, Francisco J; Díaz Mujica, Félix; Martín Tríada, Esther Lilia; Pérez Vicente, Luis; Alfonso Terry, Isabel; Pérez Milián, José; Barroso Melillo, Javier

    2010-01-01

    Se identificaron síntomas de roya naranja (Puccinia kuehnii (Krüger) Butler) en áreas experimentales de la Estación Territorial de Investigaciones de la Caña de Azúcar de Villa Clara, región central de Cuba, y se confirmó su presencia mediante diagnóstico del Laboratorio Central de Cuarentena Vegetal. Se examinaron 562 variedades, de ellas 31 comerciales, 424 progenitores, seis patrones de resistencia a roya marrón y otras en estudios de selección. La infección por P. kuehnii se detectó en 58...

  12. MARS Validation Plan and Status

    International Nuclear Information System (INIS)

    Ahn, Seung-hoon; Cho, Yong-jin

    2008-01-01

    The KINS Reactor Thermal-hydraulic Analysis System (KINS-RETAS) under development is directed toward a realistic analysis approach of best-estimate (BE) codes and realistic assumptions. In this system, MARS is pivoted to provide the BE Thermal-Hydraulic (T-H) response in core and reactor coolant system to various operational transients and accidental conditions. As required for other BE codes, the qualification is essential to ensure reliable and reasonable accuracy for a targeted MARS application. Validation is a key element of the code qualification, and determines the capability of a computer code in predicting the major phenomena expected to occur. The MARS validation was made by its developer KAERI, on basic premise that its backbone code RELAP5/MOD3.2 is well qualified against analytical solutions, test or operational data. A screening was made to select the test data for MARS validation; some models transplanted from RELAP5, if already validated and found to be acceptable, were screened out from assessment. It seems to be reasonable, but does not demonstrate whether code adequacy complies with the software QA guidelines. Especially there may be much difficulty in validating the life-cycle products such as code updates or modifications. This paper presents the plan for MARS validation, and the current implementation status

  13. Quantum degeneracy effect on performance of irreversible Otto cycle with ideal Bose gas

    International Nuclear Information System (INIS)

    Wu Feng; Chen Lingen; Sun Fengrui; Wu Chih; Guo Fangzhong; Li Qing

    2006-01-01

    An Otto cycle working with an ideal Bose gas is called a Bose Otto cycle. The internal irreversibility of the cycle is included in the factors of internal irreversibility degree. The quantum degeneracy effect on the performance of the cycle is investigated based on quantum statistical mechanics and thermodynamics. Variations of the maximum work output ratio R W and the efficiency ratio y with temperature ratio τ are examined, which reveal the influence of the quantum degeneracy of the working substance on the performance of a Bose Otto cycle. It is shown that the results obtained herein are valid under both classical and quantum ideal gas conditions

  14. Thermal-hydraulic codes validation for safety analysis of NPPs with RBMK

    International Nuclear Information System (INIS)

    Brus, N.A.; Ioussoupov, O.E.

    2000-01-01

    This work is devoted to validation of western thermal-hydraulic codes (RELAP5/MOD3 .2 and ATHLET 1.1 Cycle C) in application to Russian designed light water reactors. Such validation is needed due to features of RBMK reactor design and thermal-hydraulics in comparison with PWR and BWR reactors, for which these codes were developed and validated. These validation studies are concluded with a comparison of calculation results of modeling with the thermal-hydraulics codes with the experiments performed earlier using the thermal-hydraulics test facilities with the experimental data. (authors)

  15. Nuclear data to support computer code validation

    International Nuclear Information System (INIS)

    Fisher, S.E.; Broadhead, B.L.; DeHart, M.D.; Primm, R.T. III

    1997-04-01

    The rate of plutonium disposition will be a key parameter in determining the degree of success of the Fissile Materials Disposition Program. Estimates of the disposition rate are dependent on neutronics calculations. To ensure that these calculations are accurate, the codes and data should be validated against applicable experimental measurements. Further, before mixed-oxide (MOX) fuel can be fabricated and loaded into a reactor, the fuel vendors, fabricators, fuel transporters, reactor owners and operators, regulatory authorities, and the Department of Energy (DOE) must accept the validity of design calculations. This report presents sources of neutronics measurements that have potential application for validating reactor physics (predicting the power distribution in the reactor core), predicting the spent fuel isotopic content, predicting the decay heat generation rate, certifying criticality safety of fuel cycle facilities, and ensuring adequate radiation protection at the fuel cycle facilities and the reactor. The U.S. in-reactor experience with MOX fuel is first presented, followed by information related to other aspects of the MOX fuel performance information that is valuable to this program, but the data base remains largely proprietary. Thus, this information is not reported here. It is expected that the selected consortium will make the necessary arrangements to procure or have access to the requisite information

  16. Guide to Using the WIND Toolkit Validation Code

    Energy Technology Data Exchange (ETDEWEB)

    Lieberman-Cribbin, W.; Draxl, C.; Clifton, A.

    2014-12-01

    In response to the U.S. Department of Energy's goal of using 20% wind energy by 2030, the Wind Integration National Dataset (WIND) Toolkit was created to provide information on wind speed, wind direction, temperature, surface air pressure, and air density on more than 126,000 locations across the United States from 2007 to 2013. The numerical weather prediction model output, gridded at 2-km and at a 5-minute resolution, was further converted to detail the wind power production time series of existing and potential wind facility sites. For users of the dataset it is important that the information presented in the WIND Toolkit is accurate and that errors are known, as then corrective steps can be taken. Therefore, we provide validation code written in R that will be made public to provide users with tools to validate data of their own locations. Validation is based on statistical analyses of wind speed, using error metrics such as bias, root-mean-square error, centered root-mean-square error, mean absolute error, and percent error. Plots of diurnal cycles, annual cycles, wind roses, histograms of wind speed, and quantile-quantile plots are created to visualize how well observational data compares to model data. Ideally, validation will confirm beneficial locations to utilize wind energy and encourage regional wind integration studies using the WIND Toolkit.

  17. Material characterization and non destructive testing by ultrasounds; modelling, simulation and experimental validation; Caracterisation des materiaux et controle non destructif par ultrasons; modelisation, simulation et validation experimentale

    Energy Technology Data Exchange (ETDEWEB)

    Noroy-Nadal, M H

    2002-06-15

    This memory presents the research concerning the characterization of materials and the Non Destructive Testing (N.D.T) by ultrasonics. The different topics include three steps: modeling, computations and experimental validation. The studied materials concern mainly metals. The memory is divided in four parts. The first one concerns the characterization of materials versus temperature. The determination of the shear modulus G(T) is especially studied for a large temperature range, and around the melting point. The second part is devoted to studies by photothermal devices essentially focused on the modeling of the mechanical displacement and the stress field in coated materials. In this particular field of interest, applications concern either the mechanical characterization of the coating, the defect detection in the structure and finally the evaluation of the coating adhesion. The third section is dedicated to microstructural characterization using acoustic microscopy. The evaluation of crystallographic texture is especially approached, for metallic objects obtained by forming. Before concluding and pointing out some perspectives to this work, the last section concerns the introduction of optimization techniques, applied to the material characterization by acoustic microscopy. (author)

  18. Capacidad para tomar decisiones frente al Consentimiento Informado de personas que potencialmente participarían en estudios clínicos experimentales para la industria farmacéutica. Barranquilla (Colombia. Mayo-noviembre de 2009

    Directory of Open Access Journals (Sweden)

    Gloria Cecilia Visbal Illera

    2010-01-01

    Full Text Available Objetivo: Determinar el grado de capacidad para tomar decisiones frente al consentimiento informado de personas que potencialmente participarian en ensayos clínicos experimentales para la industria farmacéutica en la ciudad de Barranquilla. Materiales y métodos: Estudio descriptivo transversal, muestra de 100 pacientes con diagnóstico de hipertensión arterial y diabetes mellitus Tipo II; se aplicó el consentimiento informado. Se utilizó el instrumento de evaluación de competencias Competence Assessment Toolfor Clinical Research MacCAT-CR. Se calcularon estadísticas descriptivas y pruebas no paramétricas, como la prueba Ji cuadrada y la prueba de la mediana; se decidió con base en los valores de p de las respectivas pruebas. Resultados: No se encontró entendimiento de la naturaleza del estudio; ninguno obtuvo puntaje del 100% en las preguntas formuladas. El 76% de los participantes mostró un menor entendimiento de la naturaleza y propósito del estudio y un 84% no comprendió que podrían verse afectados, sin embargo, la mayoría participó. El 62% no entendió que el propósito del investigador no era proporcionar medicación, sino investigar eficacia, tolerancia y efectos de un medicamento en estudio en los seres humanos. Conclusiones: La autonomía para decidir participar en los estudios clínicos experimentales se debe basar en la confianza, cooperación, ética, diálogo, apertura al cambio y la regulación colectiva, entendiendo el proceso de consentir, aquel en que la información trasciende más allá que la de un simple formato que busca la aceptación y legalización de la información que se ha suministrado.

  19. Validation of a new version of software for monitoring the core of nuclear power plant of Laguna Verde Unit 2, at the end of Cycle 10; Validacion de una nueva version del software para monitoreo del nucleo de la Central Laguna Verde Unidad 2, al final del Ciclo 10

    Energy Technology Data Exchange (ETDEWEB)

    Hernandez, G.; Calleros, G.; Mata, F. [Comision Federal de Electricidad, Central Nucleoelectrica de Laguna Verde, Carretera Cardel-Nautla Km 42.5, Veracruz (Mexico)], e-mail: gabriel.hernandez05@cfe.gob.mx

    2009-10-15

    This work shows the differences observed in thermal limits established in the technical specifications of operation, among the new software, installed at the end of Cycle 10 of Unit 2 of nuclear power plant of Laguna Verde, and the old software that was installed from the beginning of the cycle. The methodology allowed to validate the new software during the coast down stage, before finishing the cycle, for what could be used as tool during the shutdown of Unit 2 at the end of Cycle 10. (Author)

  20. Experimental validation of a thermodynamic boiler model under steady state and dynamic conditions

    International Nuclear Information System (INIS)

    Carlon, Elisa; Verma, Vijay Kumar; Schwarz, Markus; Golicza, Laszlo; Prada, Alessandro; Baratieri, Marco; Haslinger, Walter; Schmidl, Christoph

    2015-01-01

    Highlights: • Laboratory tests on two commercially available pellet boilers. • Steady state and a dynamic load cycle tests. • Pellet boiler model calibration based on data registered in stationary operation. • Boiler model validation with reference to both stationary and dynamic operation. • Validated model suitable for coupled simulation of building and heating system. - Abstract: Nowadays dynamic building simulation is an essential tool for the design of heating systems for residential buildings. The simulation of buildings heated by biomass systems, first of all needs detailed boiler models, capable of simulating the boiler both as a stand-alone appliance and as a system component. This paper presents the calibration and validation of a boiler model by means of laboratory tests. The chosen model, i.e. TRNSYS “Type 869”, has been validated for two commercially available pellet boilers of 6 and 12 kW nominal capacities. Two test methods have been applied: the first is a steady state test at nominal load and the second is a load cycle test including stationary operation at different loads as well as transient operation. The load cycle test is representative of the boiler operation in the field and characterises the boiler’s stationary and dynamic behaviour. The model had been calibrated based on laboratory data registered during stationary operation at different loads and afterwards it was validated by simulating both the stationary and the dynamic tests. Selected parameters for the validation were the heat transfer rates to water and the water temperature profiles inside the boiler and at the boiler outlet. Modelling results showed better agreement with experimental data during stationary operation rather than during dynamic operation. Heat transfer rates to water were predicted with a maximum deviation of 10% during the stationary operation, and a maximum deviation of 30% during the dynamic load cycle. However, for both operational regimes the

  1. Effect of KOH concentration on LEO cycle life of IPV nickel-hydrogen flight battery cells

    Science.gov (United States)

    Smithrick, John J.; Hall, Stephen W.

    1990-01-01

    A breakthrough in the low-earth-orbit (LEO) cycle life of individual pressure vessel (IPV) nickel hydrogen battery cells is reported. The cycle life of boiler plate cells containing 26 percent potassium hydroxide (KOH) electrolyte was about 40,000 LEO cycles compared to 3500 cycles for cells containing 31 percent KOH. The effect of KOH concentration on cycle life was studied. The cycle regime was a stressful accelerated LEO, which consisted of a 27.5 min charge followed by a 17.5 min charge (2 x normal rate). The depth of discharge (DOD) was 80 percent. The cell temperature was maintained at 23 C. The next step is to validate these results using flight hardware and real time LEO test. NASA Lewis has a contract with the Naval Weapons Support Center (NWSC), Crane, Indiana to validate the boiler plate test results. Six 48 A-hr Hughes recirculation design IPV nickel-hydrogen flight battery cells are being evaluated. Three of the cells contain 26 percent KOH (test cells) and three contain 31 percent KOH (control cells). They are undergoing real time LEO cycle life testing. The cycle regime is a 90-min LEO orbit consisting of a 54-min charge followed by a 36-min discharge. The depth-of-discharge is 80 percent. The cell temperature is maintained at 10 C. The cells were cycled for over 8000 cycles in the continuing test. There were no failures for the cells containing 26 percent KOH. There were two failures, however, for the cells containing 31 percent KOH.

  2. Modeling and Experimental Validation of a Volumetric Expander Suitable for Waste Heat Recovery from an Automotive Internal Combustion Engine Using an Organic Rankine Cycle with Ethanol

    Directory of Open Access Journals (Sweden)

    José Galindo

    2016-04-01

    Full Text Available Waste heat recovery (WHR in exhaust gas flow of automotive engines has proved to be a useful path to increase the overall efficiency of internal combustion engines (ICE. Recovery potentials of up to 7% are shown in several works in the literature. However, most of them are theoretical estimations. Some present results from prototypes fed by steady flows generated in an auxiliary gas tank and not with actual engine exhaust gases. This paper deals with the modeling and experimental validation of an organic Rankine cycle (ORC with a swash-plate expander integrated in a 2 L turbocharged petrol engine using ethanol as working fluid. A global simulation model of the ORC was developed with a maximum difference of 5%, validated with experimental results. Considering the swash-plate as the main limiting factor, an additional specific submodel was implemented to model the physical phenomena in this element. This model allows simulating the fluid dynamic behavior of the swash-plate expander using a 0D model (Amesim. Differences up to 10.5% between tests and model results were found.

  3. Comparison of the dielectric electroactive polymer generator energy harvesting cycles

    DEFF Research Database (Denmark)

    Dimopoulos, Emmanouil; Trintis, Ionut; Munk-Nielsen, Stig

    2013-01-01

    The Dielectric ElectroActive Polymer (DEAP) generator energy harvesting cycles have been in the spotlight of the scientific interest for the past few years. Indeed, several articles have demonstrated thorough and comprehensive comparisons of the generator fundamental energy harvesting cycles......, namely Constant Charge (CC), Constant Voltage (CV) and Constant E-field (CE), based on averaged theoretical models. Yet, it has not been possible until present to validate the outcome of those comparisons via respective experimental results. In this paper, all three primary energy harvesting cycles...... are experimentally compared, based upon the coupling of a DEAP generator with a bidirectional non-isolated power electronic converter, by means of energy gain, energy harvesting efficiency and energy conversion efficiency....

  4. Study on a waste heat-driven adsorption cooling cum desalination cycle

    KAUST Repository

    Ng, Kim Choon

    2012-05-01

    This article presents the performance analysis of a waste heat-driven adsorption cycle. With the implementation of adsorption-desorption phenomena, the cycle simultaneously produces cooling energy and high-grade potable water. A mathematical model is developed using isotherm characteristics of the adsorbent/adsorbate pair (silica gel and water), energy and mass balances for the each component of the cycle. The cycle is analyzed using key performance parameters namely (i) specific cooling power (SCP), (ii) specific daily water production (SDWP), (iii) the coefficient of performance (COP) and (iv) the overall conversion ratio (OCR). The numerical results of the adsorption cycle are validated using experimental data. The parametric analysis using different hot and chilled water temperatures are reported. At 85°C hot water inlet temperature, the cycle generates 3.6 m 3 of potable water and 23 Rton of cooling at the produced chilled water temperature of 10°C. © 2012 Elsevier Ltd and IIR. All rights reserved.

  5. Alteration of 'R7T7' type nuclear glasses: statistical approach, experimental validation, local evolution model; Alteration des verres nucleaires de type 'R7T7': demarche statistique, validation experimentale, modele local d'evolution

    Energy Technology Data Exchange (ETDEWEB)

    Thierry, F

    2003-02-01

    The aim of this work is to propose an evolution of nuclear (R7T7-type) glass alteration modeling. The first part of this thesis is about development and validation of the 'r(t)' model. This model which predicts the decrease of alteration rates in confined conditions is based upon a coupling between a first-order dissolution law and a diffusion barrier effect of the alteration gel layer. The values and the uncertainties regarding the main adjustable parameters of the model ({alpha}, Dg and C*) have been determined from a systematic study of the available experimental data. A program called INVERSION has been written for this purpose. This work lead to characterize the validity domain of the 'r(t)' model and to parametrize it. Validation experiments have been undertaken, confirming the validity of the parametrization over 200 days. A new model is proposed in the second part of this thesis. It is based on an inhibition of glass dissolution reaction by silicon coupled with a local description of silicon retention in the alteration gel layer. This model predicts the evolutions of boron and silicon concentrations in solution as well as the concentrations and retention profiles in the gel layer. These predictions have been compared to measurements of retention profiles by the secondary ion mass spectrometry (SIMS) method. The model has been validated on fractions of gel layer which reactivity present low or moderate disparities. (author)

  6. Five-Kilometers Time Trial: Preliminary Validation of a Short Test for Cycling Performance Evaluation.

    Science.gov (United States)

    Dantas, Jose Luiz; Pereira, Gleber; Nakamura, Fabio Yuzo

    2015-09-01

    The five-kilometer time trial (TT5km) has been used to assess aerobic endurance performance without further investigation of its validity. This study aimed to perform a preliminary validation of the TT5km to rank well-trained cyclists based on aerobic endurance fitness and assess changes of the aerobic endurance performance. After the incremental test, 20 cyclists (age = 31.3 ± 7.9 years; body mass index = 22.7 ± 1.5 kg/m(2); maximal aerobic power = 360.5 ± 49.5 W) performed the TT5km twice, collecting performance (time to complete, absolute and relative power output, average speed) and physiological responses (heart rate and electromyography activity). The validation criteria were pacing strategy, absolute and relative reliability, validity, and sensitivity. Sensitivity index was obtained from the ratio between the smallest worthwhile change and typical error. The TT5km showed high absolute (coefficient of variation 0.95) reliability of performance variables, whereas it presented low reliability of physiological responses. The TT5km performance variables were highly correlated with the aerobic endurance indices obtained from incremental test (r > 0.70). These variables showed adequate sensitivity index (> 1). TT5km is a valid test to rank the aerobic endurance fitness of well-trained cyclists and to differentiate changes on aerobic endurance performance. Coaches can detect performance changes through either absolute (± 17.7 W) or relative power output (± 0.3 W.kg(-1)), the time to complete the test (± 13.4 s) and the average speed (± 1.0 km.h(-1)). Furthermore, TT5km performance can also be used to rank the athletes according to their aerobic endurance fitness.

  7. High performance integrated solar combined cycles with minimum modifications to the combined cycle power plant design

    International Nuclear Information System (INIS)

    Manente, Giovanni

    2016-01-01

    Highlights: • Off-design model of a 390 MW_e three pressure combined cycle developed and validated. • The off-design model is used to evaluate different hybridization schemes with solar. • Power boosting and fuel saving with different design modifications are considered. • Maximum solar share of total electricity is only 1% with the existing equipment. • The maximum incremental solar radiation-to-electrical efficiency approaches 29%. - Abstract: The integration of solar energy into natural gas combined cycles has been successfully demonstrated in several integrated solar combined cycles since the beginning of this decade in many countries. There are many motivations that drive investments on integrated solar combined cycles which are primarily the repowering of existing power plants, the compliance with more severe environmental laws on emissions and the mitigation of risks associated with large solar projects. Integrated solar combined cycles are usually developed as brownfield facilities by retrofitting existing natural gas combined cycles and keeping the existing equipment to minimize costs. In this work a detailed off-design model of a 390 MW_e three pressure level natural gas combined cycle is built to evaluate different integration schemes of solar energy which either keep the equipment of the combined cycle unchanged or include new equipment (steam turbine, heat recovery steam generator). Both power boosting and fuel saving operation strategies are analyzed in the search for the highest annual efficiency and solar share. Results show that the maximum incremental power output from solar at design solar irradiance is limited to 19 MW_e without modifications to the existing equipment. Higher values are attainable only including a larger steam turbine. High solar radiation-to-electrical efficiencies in the range 24–29% can be achieved in the integrated solar combined cycle depending on solar share and extension of tube banks in the heat recovery

  8. A New Dynamic Model for Nuclear Fuel Cycle System Analysis

    International Nuclear Information System (INIS)

    Choi, Sungyeol; Ko, Won Il

    2014-01-01

    The evaluation of mass flow is a complex process where numerous parameters and their complex interaction are involved. Given that many nuclear power countries have light and heavy water reactors and associated fuel cycle technologies, the mass flow analysis has to consider a dynamic transition from the open fuel cycle to other cycles over decades or a century. Although an equilibrium analysis provides insight concerning the end-states of fuel cycle transitions, it cannot answer when we need specific management options, whether the current plan can deliver these options when needed, and how fast the equilibrium can be achieved. As a pilot application, the government brought several experts together to conduct preliminary evaluations for nuclear fuel cycle options in 2010. According to Table 1, they concluded that the closed nuclear fuel cycle has long-term advantages over the open fuel cycle. However, it is still necessary to assess these options in depth and to optimize transition paths of these long-term options with advanced dynamic fuel cycle models. A dynamic simulation model for nuclear fuel cycle systems was developed and its dynamic mass flow analysis capability was validated against the results of existing models. This model can reflects a complex combination of various fuel cycle processes and reactor types, from once-through to multiple recycling, within a single nuclear fuel cycle system. For the open fuel cycle, the results of the developed model are well matched with the results of other models

  9. 40 CFR 1045.501 - How do I run a valid emission test?

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false How do I run a valid emission test... Procedures § 1045.501 How do I run a valid emission test? (a) Applicability. This subpart is addressed to you... maximum test speed. (g) Special and alternate procedures. If you are unable to run the duty cycle...

  10. Análisis de la degeneración de los fotorreceptoes en modelos experimentales de retinosis pigmentaria, degeneración macular asociada a la edad y glaucoma =Analysis of photoreceptor degeneration in experimental models of retinitis pigmentosa, aging macular degeneration and glaucoma

    OpenAIRE

    Ortín Martínez, Arturo

    2015-01-01

    . Objetivo. Determinar el número total y la topografía de la población de conos en roedores adultos utilizando rutinas automatizadas que nos permita investigar objetivamente los efectos de diferentes modelos experimentales de patologías humanas tales como la degeneración macular asociada a la edad (DMAE), retinosis pigmentaria (RP) y la neuropatía óptica glaucomatosa (NOG) sobre la población de fotorreceptores. Material y métodos. Se han utilizado cinco cepas distinta de roedor...

  11. Análisis de la degeneración de los fotorreceptoes en modelos experimentales de retinosis pigmentaria, degeneración macular asociada a la edad y glaucoma =Analysis of photoreceptor degeneration in experimental models of retinitis pigmentosa, aging macular degeneration and glaucoma

    OpenAIRE

    Ortín Martínez, Arturo

    2015-01-01

    Objetivo. Determinar el número total y la topografía de la población de conos en roedores adultos utilizando rutinas automatizadas que nos permita investigar objetivamente los efectos de diferentes modelos experimentales de patologías humanas tales como la degeneración macular asociada a la edad (DMAE), retinosis pigmentaria (RP) y la neuropatía óptica glaucomatosa (NOG) sobre la población de fotorreceptores. Material y métodos. Se han utilizado cinco cepas distinta de roedores: Sprague-Dawle...

  12. Simplified theory of gas-jet pumps and experimental verification; Theorie simplifiee des trompes a gaz et verification experimentale

    Energy Technology Data Exchange (ETDEWEB)

    Costes, D [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1964-07-01

    With a view to using the gas-jet pump in the fuel-study loops of gas reactors, a theory is developed for an unidimensional mixer, applicable to the case of low compression ratios in the induced current. This theory makes it possible to optimize the diameter of the mixer if the pressure-drop coefficient {alpha} of the mixer is known with respect to the induced current. An experimental study has made it possible to define the geometry suitable for such pumps, and to provide a remarkably constant value of {alpha} for the economically advantageous designs; this makes it possible to define simply the geometry of the optimized pump as a function of the geometry of the circuit in use, and independently of the flow-rate conditions. (author) [French] Dans le but d'utiliser la pompe a jet (ou trompe) dans des boucles d'etude de combustible des piles a gaz, on etablit une theorie du melangeur unidimensionnel, applicable dans la cas des faibles rapports de compression dans le courant induit. Cette theorie permet l'optimisation du diametre de melangeur, moyennant la connaissance du coefficient {alpha} de pertes de charge de celui-ci, relativement au courant induit. Une recherche experimentale a permis de preciser la geometrie a adopter dans de telles pompes, et fourni pour {alpha} une valeur remarquablement constante dans les configurations economiquement interessantes, ce qui permet de definir simplement la geometrie de la pompe optimisee en fonction de la geometrie du circuit d'utilisation et independamment des conditions de debit. (auteur)

  13. Lithium-Ion Cell Fault Detection by Single-Point Impedance Diagnostic and Degradation Mechanism Validation for Series-Wired Batteries Cycled at 0 °C

    Directory of Open Access Journals (Sweden)

    Corey T. Love

    2018-04-01

    Full Text Available The utility of a single-point impedance-based technique to monitor the state-of-health of a pack of four 18650 lithium-ion cells wired in series (4S was demonstrated in a previous publication. This work broadens the applicability of the single-point monitoring technique to identify temperature induced faults within 4S packs at 0 °C by two distinct discharge cut-off thresholds: individual cell cut-off and pack voltage cut-off. The results show how the single-point technique applied to a 4S pack can identify cell faults induced by low temperature degradation when plotted on a unique state-of-health map. Cell degradation is validated through an extensive incremental capacity technique to quantify capacity loss due to low temperature cycling and investigate the underpinnings of cell failure.

  14. High cycle fatigue of Type 422 stainless steel

    International Nuclear Information System (INIS)

    Soo, P.; Chow, J.G.Y.; Sabatini, R.L.

    1978-01-01

    High cycle fatigue testing has been carried out on Type 422 stainless steel to determine the performance of cyclically stressed disks and blades in the main and auxiliary HTGR helium circulators. Tests were performed at 316, 482, and 538 0 C (600, 900, and 1000 0 F) in air for the fully reversible and mean load conditions. Goodman's analysis is shown to be valid in predicting failure at 316 0 C (600 0 F), marginally valid at 482 0 C (900 0 F), and probably invalid at 538 0 C (1000 0 F). Metallographic analyses were conducted to characterize the nature of failure for the temperatures and loading conditions investigated

  15. Validity and reliability of the Utrecht Work Engagement Scale-Student Version in Sri Lanka.

    Science.gov (United States)

    Wickramasinghe, Nuwan Darshana; Dissanayake, Devani Sakunthala; Abeywardena, Gihan Sajiwa

    2018-05-04

    The present study was aimed at assessing the validity and the reliability of the Sinhala version of the Utrecht Work Engagement Scale-Student Version (UWES-S) among collegiate cycle students in Sri Lanka. The 17-item UWES-S was translated to Sinhala and the judgmental validity was assessed by a multi-disciplinary panel of experts. Construct validity of the UWES-S was appraised by using multi-trait scaling analysis and exploratory factor analysis (EFA) on data obtained from a sample of 194 grade thirteen students in the Kurunegala district, Sri Lanka. Reliability of the UWES-S was assessed by using internal consistency and test-retest reliability. Except for item 13, all other items showed good psychometric properties in judgemental validity, item-convergent validity and item-discriminant validity. EFA using principal component analysis with Oblimin rotation, suggested a three-factor solution (including vigor, dedication and absorption subscales) explaining 65.4% of the total variance for the 16-item UWES-S (with item 13 deleted). All three subscales show high internal consistency with Cronbach's α coefficient values of 0.867, 0.819, and 0.903 and test-retest reliability was high (p valid and a reliable instrument to assess work engagement among collegiate cycle students in Sri Lanka.

  16. Evaluation experimentale et theorique du comportement a la flexion de nouveaux poteaux en materiaux composites

    Science.gov (United States)

    Metiche, Slimane

    La demande croissante en poteaux pour les differents reseaux d'electricite et de telecommunications a rendu necessaire l'utilisation de materiaux innovants, qui preservent l'environnement. La majorite des poteaux electriques existants au Canada ainsi qu'a travers le monde, sont fabriques a partir de materiaux traditionnels tel que le bois, le beton ou l'acier. Les motivations des industriels et des chercheurs a penser a d'autres solutions sont diverses, citons entre autre: La limitation en longueur des poteaux en bois ainsi que la vulnerabilite des poteaux fabriques en beton ou en acier aux agressions climatiques. Les nouveaux poteaux en materiaux composites se presentent comme de bons candidats a cet effet, cependant; leur comportement structural n'est pas connu et des etudes theoriques et experimentales approfondies sont necessaires avant leur mise en marche a grande echelle. Un programme de recherche intensif comportant plusieurs projets experimentaux, analytiques et numeriques est en cours a l'Universite de Sherbrooke afin d'evaluer le comportement a court et a long termes de ces nouveaux poteaux en Polymeres Renforces de Fibres (PRF). C'est dans ce contexte que s'inscrit la presente these, et notre recherche vise a evaluer le comportement a la flexion de nouveaux poteaux tubulaires coniques fabriques en materiaux composites par enroulement filamentaire et ce, a travers une etude theorique, ainsi qu'a travers une serie d'essais de flexion en "grandeur reelle" afin de comprendre le comportement structural de ces poteaux, d'optimiser la conception et de proposer une procedure de dimensionnement pour les utilisateurs. Les poteaux en Polymeres Renforces de Fibres (PRF) etudies dans cette these sont fabriques avec une resine epoxyde renforcee de fibres de verre type E. Chaque type poteaux est constitue principalement de trois zones ou les proprietes geometriques (epaisseur, diametre) et les proprietes mecaniques sont differentes d'une zone a l'autre. La difference

  17. Neutronics validation during conversion to LEU

    International Nuclear Information System (INIS)

    Hendriks, J. A.; Sciolla, C. M.; Van Der Marck, S. C.; Valko, J.

    2006-01-01

    From October 2005 to May 2006 the High Flux Reactor at Petten, the Netherlands, was progressively converted to low-enriched uranium. The core calculations were performed with two code systems, one being Rebus/MCNP, the other being Oscar-3. These systems were chosen because Rebus (for fuel burn-up) and MCNP (for flux, power, and activation reaction rates) have a long and good track record, whereas Oscar-3 is a newer code, with more user-friendly interfaces that facilitate day to day and cycle to cycle variable input generation. The following measurements have been used for validation of the neutronics calculations: control rod settings at begin and end of cycle, reactivity of control rods, Cu-wire activation during low power runs of the reactor, activation monitor sets present during part of the full power cycle, and isotope production measurements. We report on a comparison of measurements and calculational results for the control rod settings, Cu-wire activation and monitor set data. The Cu-wire activation results are mostly within 10% of experimental values, the monitor set activation results are easily within 5%, based on absolute predictions from the calculations. (authors)

  18. A Decision Support System to Choose Optimal Release Cycle Length in Incremental Software Development Environments

    OpenAIRE

    Suman, Avnish Chandra; Mishra, Saraswati; Anand, Abhinav

    2016-01-01

    In the last few years it has been seen that many software vendors have started delivering projects incrementally with very short release cycles. Best examples of success of this approach has been Ubuntu Operating system that has a 6 months release cycle and popular web browsers such as Google Chrome, Opera, Mozilla Firefox. However there is very little knowledge available to the project managers to validate the chosen release cycle length. We propose a decision support system that...

  19. Effect of KOH concentration on LEO cycle life of IPV nickel-hydrogen flight cells-update 2

    Science.gov (United States)

    Smithrick, John J.; Hall, Stephen W.

    1991-01-01

    An update of validation test results confirming the breakthrough in low earth orbit (LEO) cycle life of nickel-hydrogen cells containing 26 percent KOH electrolyte is presented. A breakthrough in the LEO cycle life of individual pressure vessel (IPV nickel-hydrogen cells has been previously reported. The cycle life of boiler plate cells containing 26 percent potassium hydroxide (KOH) electrolyte was about 40 000 LEO cycles compared to 3500 cycles for cells containing 31 percent KOH. This test was conducted at Hughes Aircraft Company under a NASA Lewis contract. The purpose was to investigate the effect of KOH concentration on cycle life. The cycle regime was a stressful accelerated LEO, which consisted of a 27.5 min charge followed by a 17.5 min discharge (2x normal rate). The depth of discharge (DOD) was 80 percent. The cell temperature was maintained at 23 C. The boiler plate test results are in the process of being validated using flight hardware and real time LEO test at the Naval Weapons Support Center (NWSC), Crane, Indiana under a NASA Lewis Contract. Six 48 Ah Hughes recirculation design IPV nickel-hydrogen flight battery cells are being evaluated. Three of the cells contain 26 percent KOH (test cells), and three contain 31 percent KOH (control cells). They are undergoing real time LEO cycle life testing. The cycle regime is a 90-min LEO orbit consisting of a 54-min charge followed by a 36-min discharge. The depth-of-discharge is 80 percent. The cell temperature is maintained at 10 C. The three 31 percent KOH cells failed (cycles 3729, 4165, and 11355). One of the 26 percent KOH cells failed at cycle 15314. The other two 26 percent KOH cells were cycled for over 16600 cycles during the continuing test.

  20. 40 CFR 1048.501 - How do I run a valid emission test?

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false How do I run a valid emission test... § 1048.501 How do I run a valid emission test? (a) Use the equipment and procedures for spark-ignition... 86.132-96(h) and then operate the engine for 60 minutes over repeat runs of the duty cycle specified...

  1. Sensitivity Variation on Low Cycle Fatigue Cracks Using Level 4/Method B Penetrant

    Energy Technology Data Exchange (ETDEWEB)

    FULWOOD,HARRY; MOORE,DAVID G.

    1999-09-02

    The Federal Aviation Administration's Airworthiness Assurance NDI Validation Center (AANC) is currently conducting experiments with Level 4, Method B penetrant on low cycle fatigue specimens. The main focus of these experiments is to document the affect on penetrant brightness readings by varying inspection parameters. This paper discusses the results of changing drying temperature, drying time, and dwell time of both penetrant and emulsifier on low cycle fatigue specimens.

  2. Effects of combustion efficiency on a Dual cycle

    International Nuclear Information System (INIS)

    Ozsoysal, Osman Azmi

    2009-01-01

    This paper studies a Dual cycle model containing irreversibilities coming exclusively from expansion and compression processes. It is assumed that any fraction of the fuel's chemical energy can not fully released inside the engine because of the incomplete combustion. Utilizing the combustion efficiency is found to be more useful to realize the cycle feasibility. Amount of the released energy from fuel into the cylinder restricts the compression ratio. It is presented how the upper limit of compression ratio is evaluated by means of using some constraints for realizing a Dual cycle. Valid ranges of the constraints given in literature seriously affect the feasibility of cycle. Developed mathematical model leads to a qualitative understanding of how engine loss can be reduced. Thermal efficiency-work curves cannot have a closed loop shape because there is a close relationship between the fuel energy, air-fuel mass ratio, combustion efficiency, maximum cycle temperature and the heat losses into the cylinder wall. If these are all omitted, while heat losses are determined independently without establishing any relationship between the released fuel energy, the thermal efficiency versus work curves will just be able to have a closed loop shape. This is the original perspective and contribution of paper.

  3. Analysis of zeotropic mixtures used in high-temperature Organic Rankine cycle

    International Nuclear Information System (INIS)

    Dong, Bensi; Xu, Guoqiang; Cai, Yi; Li, Haiwang

    2014-01-01

    Highlights: • Using mixtures leads to an efficiency increase compared to pure fluids. • MM/MDM (0.4/0.6) produces optimal cycle efficiency. • Lower temperature gradients of heat source and sink give rise to higher cycle efficiency. • Condensation step shows more effect than evaporation step on cycle efficiency. - Abstract: The paper investigates the performance of high-temperature Organic Rankine cycle (ORC) with zeotropic mixtures as working fluid. A numerical model, which has been validated by comparing with the published data, is developed to predict the first law thermal efficiency of the cycle. The effects of mixture concentration, temperature gradient of the heat transfer fluid, pinch temperature difference, pressure ratio, and condensation pressure on the first law efficiency are presented firstly using a purposely designed program, and then the suitable conditions for the described ORC are suggested based on the results of the simulation. It is demonstrated that the use of zeotropic mixtures leads to an efficiency increase compared to pure fluids

  4. Cycle length maximization in PWRs using empirical core models

    International Nuclear Information System (INIS)

    Okafor, K.C.; Aldemir, T.

    1987-01-01

    The problem of maximizing cycle length in nuclear reactors through optimal fuel and poison management has been addressed by many investigators. An often-used neutronic modeling technique is to find correlations between the state and control variables to describe the response of the core to changes in the control variables. In this study, a set of linear correlations, generated by two-dimensional diffusion-depletion calculations, is used to find the enrichment distribution that maximizes cycle length for the initial core of a pressurized water reactor (PWR). These correlations (a) incorporate the effect of composition changes in all the control zones on a given fuel assembly and (b) are valid for a given range of control variables. The advantage of using such correlations is that the cycle length maximization problem can be reduced to a linear programming problem

  5. Validating the Learning Cycle Models of Business Simulation Games via Student Perceived Gains in Skills and Knowledge

    Science.gov (United States)

    Tao, Yu-Hui; Yeh, C. Rosa; Hung, Kung Chin

    2015-01-01

    Several theoretical models have been constructed to determine the effects of buisness simulation games (BSGs) on learning performance. Although these models agree on the concept of learning-cycle effect, no empirical evidence supports the claim that the use of learning cycle activities with BSGs produces an effect on incremental gains in knowledge…

  6. Life Cycle Assessment of two Electrolux electric cookers: ELK8200AL and EKV5600

    DEFF Research Database (Denmark)

    Hansen, Morten Søes; Wenzel, Henrik; Frees, Niels

    A life cycle assessment of two electrical cookers was made for the company Electrolux A/S. A number of valid conclusions can be drawn from the study. The conclusions are supported by a sensitivity analysis covering essential parameter variations and showing that quite robust conclusions can...... issue for the resource consumption of the cookers over their life cycle • Transportation of the cookers over their life cycle is insignificant Environmentally, the main perspectives for improvements lie in the optimisation of the use stage, including better efficiency in transformation of the energy...

  7. Mollusc reproductive toxicity tests - Development and validation of test guidelines

    DEFF Research Database (Denmark)

    Ducrot, Virginie; Holbech, Henrik; Kinnberg, Karin Lund

    . Draft standard operating procedures (SOPs) have been designed based upon literature and expert knowledge from project partners. Pre-validation studies have been implemented to validate the proposed test conditions and identify issues in performing the SOPs and analyzing test results. Pre-validation work......The Organisation for Economic Cooperation and Development is promoting the development and validation of mollusc toxicity tests within its test guidelines programme, eventually aiming for the standardization of mollusc apical toxicity tests. Through collaborative work between academia, industry...... and stakeholders, this study aims to develop innovative partial life-cycle tests on the reproduction of the freshwater gastropods Potamopyrgus antipodarum and Lymnaea stagnalis, which are relevant candidate species for the standardization of mollusc apical toxicity tests assessing reprotoxic effects of chemicals...

  8. Modeling of a Von Platen-Munters diffusion absorption refrigeration cycle

    Science.gov (United States)

    Agostini, Bruno; Agostini, Francesco; Habert, Mathieu

    2016-09-01

    This article presents a thermodynamical model of a Von-Platen diffusion absorption refrigeration cycle for power electronics applications. It is first validated by comparison with data available in the literature for the classical water-ammonia-helium cycle for commercial absorption fridges. Then new operating conditions corresponding to specific ABB applications, namely high ambient temperature and new organic fluids combinations compatible with aluminium are simulated and discussed. The target application is to cool power electronics converters in harsh environments with high ambient temperature by providing refrigeration without compressor, for passive components losses of about 500 W, with a compact and low cost solution.

  9. Validation of the REBUS-3/RCT methodologies for EBR-II core-follow analysis

    International Nuclear Information System (INIS)

    McKnight, R.D.

    1992-01-01

    One of the many tasks to be completed at EBR-2/FCF (Fuel Cycle Facility) regarding fuel cycle closure for the Integral Fast Reactor (IFR) is to develop and install the systems to be used for fissile material accountancy and control. The IFR fuel cycle and pyrometallurgical process scheme determine the degree of actinide of actinide buildup in the reload fuel assemblies. Inventories of curium, americium and neptunium in the fuel will affect the radiation and thermal environmental conditions at the fuel fabrication stations, the chemistry of reprocessing, and the neutronic performance of the core. Thus, it is important that validated calculational tools be put in place for accurately determining isotopic mass and neutronic inputs to FCF for both operational and material control and accountancy purposes. The primary goal of this work is to validate the REBUS-2/RCT codes as tools which can adequately compute the burnup and isotopic distribution in binary- and ternary-fueled Mark-3, Mark-4, and Mark-5 subassemblies. 6 refs

  10. Preliminary Validation and Verification Plan for CAREM Reactor Protection System

    International Nuclear Information System (INIS)

    Fittipaldi, Ana; Maciel Felix

    2000-01-01

    The purpose of this paper, is to present a preliminary validation and verification plan for a particular architecture proposed for the CAREM reactor protection system with software modules (computer based system).These software modules can be either own design systems or systems based in commercial modules such as programmable logic controllers (PLC) redundant of last generation.During this study, it was seen that this plan can also be used as a validation and verification plan of commercial products (COTS, commercial off the shelf) and/or smart transmitters.The software life cycle proposed and its features are presented, and also the advantages of the preliminary validation and verification plan

  11. Investigation of Cycle-to-Cycle Variability of NO in Homogeneous Combustion

    Directory of Open Access Journals (Sweden)

    Karvountzis-Kontakiotis A.

    2015-01-01

    Full Text Available Cyclic variability of spark ignition engines is recognized as a scatter in the combustion parameter recordings during actual operation in steady state conditions. Combustion variability may occur due to fluctuations in both early flame kernel development and in turbulent flame propagation with an impact on fuel consumption and emissions. In this study, a detailed chemistry model for the prediction of NO formation in homogeneous engine conditions is presented. The Wiebe parameterization is used for the prediction of heat release; then the calculated thermodynamic data are fed into the chemistry model to predict NO evolution at each degree of crank angle. Experimental data obtained from literature studies were used to validate the mean NO levels calculated. Then the model was applied to predict the impact of cyclic variability on mean NO and the amplitude of its variation. The cyclic variability was simulated by introducing random perturbations, which followed a normal distribution, to the Wiebe function parameters. The results of this approach show that the model proposed better predicts mean NO formation than earlier methods. Also, it shows that to the non linear formation rate of NO with temperature, cycle-to-cycle variation leads to higher mean NO emission levels than what one would predict without taking cyclic variation into account.

  12. Intelligent Testing of Traffic Light Programs: Validation in Smart Mobility Scenarios

    OpenAIRE

    Javier Ferrer; José García-Nieto; Enrique Alba; Francisco Chicano

    2016-01-01

    In smart cities, the use of intelligent automatic techniques to find efficient cycle programs of traffic lights is becoming an innovative front for traffic flow management. However, this automatic programming of traffic lights requires a validation process of the generated solutions, since they can affect the mobility (and security) of millions of citizens. In this paper, we propose a validation strategy based on genetic algorithms and feature models for the automatic generation of different ...

  13. Benchmark for evaluation and validation of reactor simulations (BEAVRS)

    Energy Technology Data Exchange (ETDEWEB)

    Horelik, N.; Herman, B.; Forget, B.; Smith, K. [Massachusetts Institute of Technology, Department of Nuclear Science and Engineering, 77 Massachusetts Avenue, Cambridge, MA 02139 (United States)

    2013-07-01

    Advances in parallel computing have made possible the development of high-fidelity tools for the design and analysis of nuclear reactor cores, and such tools require extensive verification and validation. This paper introduces BEAVRS, a new multi-cycle full-core Pressurized Water Reactor (PWR) depletion benchmark based on two operational cycles of a commercial nuclear power plant that provides a detailed description of fuel assemblies, burnable absorbers, in-core fission detectors, core loading patterns, and numerous in-vessel components. This benchmark enables analysts to develop extremely detailed reactor core models that can be used for testing and validation of coupled neutron transport, thermal-hydraulics, and fuel isotopic depletion. The benchmark also provides measured reactor data for Hot Zero Power (HZP) physics tests, boron letdown curves, and three-dimensional in-core flux maps from fifty-eight instrumented assemblies. Initial comparisons between calculations performed with MIT's OpenMC Monte Carlo neutron transport code and measured cycle 1 HZP test data are presented, and these results display an average deviation of approximately 100 pcm for the various critical configurations and control rod worth measurements. Computed HZP radial fission detector flux maps also agree reasonably well with the available measured data. All results indicate that this benchmark will be extremely useful in validation of coupled-physics codes and uncertainty quantification of in-core physics computational predictions. The detailed BEAVRS specification and its associated data package is hosted online at the MIT Computational Reactor Physics Group web site (http://crpg.mit.edu/), where future revisions and refinements to the benchmark specification will be made publicly available. (authors)

  14. Validation of Lifetime Prediction of IGBT Modules Based on Linear Damage Accumulation by Means of Superimposed Power Cycling Tests

    DEFF Research Database (Denmark)

    Choi, Ui-Min; Ma, Ke; Blaabjerg, Frede

    2018-01-01

    In this paper, the lifetime prediction of power device modules based on the linear damage accumulation is studied in conjunction with simple mission profiles of converters. Superimposed power cycling conditions, which are called simple mission profiles in this paper, are made based on a lifetime ...... prediction of IGBT modules under power converter applications.......In this paper, the lifetime prediction of power device modules based on the linear damage accumulation is studied in conjunction with simple mission profiles of converters. Superimposed power cycling conditions, which are called simple mission profiles in this paper, are made based on a lifetime...... model in respect to junction temperature swing duration. This model has been built based on 39 power cycling test results of 600-V 30-A three-phase-molded IGBT modules. Six tests are performed under three superimposed power cycling conditions using an advanced power cycling test setup. The experimental...

  15. Bipolar mood cycles and lunar tidal cycles.

    Science.gov (United States)

    Wehr, T A

    2018-04-01

    In 17 patients with rapid cycling bipolar disorder, time-series analyses detected synchronies between mood cycles and three lunar cycles that modulate the amplitude of the moon's semi-diurnal gravimetric tides: the 14.8-day spring-neap cycle, the 13.7-day declination cycle and the 206-day cycle of perigee-syzygies ('supermoons'). The analyses also revealed shifts among 1:2, 1:3, 2:3 and other modes of coupling of mood cycles to the two bi-weekly lunar cycles. These shifts appear to be responses to the conflicting demands of the mood cycles' being entrained simultaneously to two different bi-weekly lunar cycles with slightly different periods. Measurements of circadian rhythms in body temperature suggest a biological mechanism through which transits of one of the moon's semi-diurnal gravimetric tides might have driven the patients' bipolar cycles, by periodically entraining the circadian pacemaker to its 24.84-h rhythm and altering the pacemaker's phase-relationship to sleep in a manner that is known to cause switches from depression to mania.

  16. IV&V Project Assessment Process Validation

    Science.gov (United States)

    Driskell, Stephen

    2012-01-01

    The Space Launch System (SLS) will launch NASA's Multi-Purpose Crew Vehicle (MPCV). This launch vehicle will provide American launch capability for human exploration and travelling beyond Earth orbit. SLS is designed to be flexible for crew or cargo missions. The first test flight is scheduled for December 2017. The SLS SRR/SDR provided insight into the project development life cycle. NASA IV&V ran the standard Risk Based Assessment and Portfolio Based Risk Assessment to identify analysis tasking for the SLS program. This presentation examines the SLS System Requirements Review/System Definition Review (SRR/SDR), IV&V findings for IV&V process validation correlation to/from the selected IV&V tasking and capabilities. It also provides a reusable IEEE 1012 scorecard for programmatic completeness across the software development life cycle.

  17. An integrated approach for the validation of energy and environmental system analysis models : used in the validation of the Flexigas Excel BioGas model

    NARCIS (Netherlands)

    Pierie, Frank; van Someren, Christian; Liu, Wen; Bekkering, Jan; Hengeveld, Evert Jan; Holstein, J.; Benders, René M.J.; Laugs, Gideon A.H.; van Gemert, Wim; Moll, Henri C.

    2016-01-01

    A review has been completed for a verification and validation (V&V) of the (Excel) BioGas simulator or EBS model. The EBS model calculates the environmental impact of biogas production pathways using Material and Energy Flow Analysis, time dependent dynamics, geographic information, and Life Cycle

  18. Computational analysis of supercritical CO2 Brayton cycle power conversion system for fusion reactor

    International Nuclear Information System (INIS)

    Halimi, Burhanuddin; Suh, Kune Y.

    2012-01-01

    Highlights: ► Computational analysis of S-CO 2 Brayton cycle power conversion system. ► Validation of numerical model with literature data. ► Recompression S-CO 2 Brayton cycle thermal efficiency of 42.44%. ► Reheating concept to enhance the cycle thermal efficiency. ► Higher efficiency achieved by the proposed concept. - Abstract: The Optimized Supercritical Cycle Analysis (OSCA) code is being developed to analyze the design of a supercritical carbon dioxide (S-CO 2 ) driven Brayton cycle for a fusion reactor as part of the Modular Optimal Balance Integral System (MOBIS). This system is based on a recompression Brayton cycle. S-CO 2 is adopted as the working fluid for MOBIS because of its easy availability, high density and low chemical reactivity. The reheating concept is introduced to enhance the cycle thermal efficiency. The helium-cooled lithium lead model AB of DEMO fusion reactor is used as reference in this paper.

  19. Work plan for improving the DARWIN2.3 depleted material balance calculation of nuclides of interest for the fuel cycle

    Directory of Open Access Journals (Sweden)

    Rizzo Axel

    2017-01-01

    Full Text Available DARWIN2.3 is the reference package used for fuel cycle applications in France. It solves the Boltzmann and Bateman equations in a coupling way, with the European JEFF-3.1.1 nuclear data library, to compute the fuel cycle values of interest. It includes both deterministic transport codes APOLLO2 (for light water reactors and ERANOS2 (for fast reactors, and the DARWIN/PEPIN2 depletion code, each of them being developed by CEA/DEN with the support of its industrial partners. The DARWIN2.3 package has been experimentally validated for pressurized and boiling water reactors, as well as for sodium fast reactors; this experimental validation relies on the analysis of post-irradiation experiments (PIE. The DARWIN2.3 experimental validation work points out some isotopes for which the depleted concentration calculation can be improved. Some other nuclides have no available experimental validation, and their concentration calculation uncertainty is provided by the propagation of a priori nuclear data uncertainties. This paper describes the work plan of studies initiated this year to improve the accuracy of the DARWIN2.3 depleted material balance calculation concerning some nuclides of interest for the fuel cycle.

  20. Work plan for improving the DARWIN2.3 depleted material balance calculation of nuclides of interest for the fuel cycle

    Science.gov (United States)

    Rizzo, Axel; Vaglio-Gaudard, Claire; Martin, Julie-Fiona; Noguère, Gilles; Eschbach, Romain

    2017-09-01

    DARWIN2.3 is the reference package used for fuel cycle applications in France. It solves the Boltzmann and Bateman equations in a coupling way, with the European JEFF-3.1.1 nuclear data library, to compute the fuel cycle values of interest. It includes both deterministic transport codes APOLLO2 (for light water reactors) and ERANOS2 (for fast reactors), and the DARWIN/PEPIN2 depletion code, each of them being developed by CEA/DEN with the support of its industrial partners. The DARWIN2.3 package has been experimentally validated for pressurized and boiling water reactors, as well as for sodium fast reactors; this experimental validation relies on the analysis of post-irradiation experiments (PIE). The DARWIN2.3 experimental validation work points out some isotopes for which the depleted concentration calculation can be improved. Some other nuclides have no available experimental validation, and their concentration calculation uncertainty is provided by the propagation of a priori nuclear data uncertainties. This paper describes the work plan of studies initiated this year to improve the accuracy of the DARWIN2.3 depleted material balance calculation concerning some nuclides of interest for the fuel cycle.

  1. Loxoscelismo en Chile: estudios epidemiológicos, clínicos y experimentales Loxoscelism in Chile: epidemiological, clinical and experimental studies

    Directory of Open Access Journals (Sweden)

    Hugo Schenone

    1989-12-01

    Full Text Available Se presenta un enfoque panorámico de estudios epidemiológicos, clínicos y experimentales referentes a Loxosceles laeta y loxoscelismo efectuados en 1955-1988 en Santiago, Chile. Se estudiaron 216 casos de loxoscelismo. Los hechos más relevantes fueron: 52,8% correspondió a mujeres; edad entre 7 meses y 78 años; 84,3% fué loxoscelismo cutáneo (LO y 15,7% loxoscelismo cutáneo-visceral (LCV; 73,6% sucedió en época calurosa; en 86,6% el accidente ocurrió en la vivienda, especialmente en dormitorios, mientras la persona dormía o se vestía. La araña fué vista en 60,2% de los casos e identificada en laboratorio como L. laeta en 17,7% (10,6% de los 216 casos. Los sitios más frecuen temente afectados fueron las extremidades con 67,6%, lancetazo urente fué el síntoma inicial más frecuente. Dolor, edema y placa livedoide, la cual posteriormente se transformaría en escara necrótica, fueron las manifestaciones locales predominantes. En LCV hematuria y hemoglobinuria fueron constantes, ictericia, fiebre y compromiso de conciencia se presentaron en la mayoría de los casos. Tratamiento: LC con antihistamínicos o corticoides inyectables, LCV con corti-coides inyectables. La condición de los pacientes en el último control fué: curación completa en 75,5%, curación con secuela cicatrizal en 8,3%, muerte en 3,7% (todos con LCV y abandono en 12,5%. Adicionalmente, se ha efectuado una serie de estudios experimentales, tanto in vivo como in vitro para esclarecer aspectos básicos sobre el veneno de L. laeta y el tratamiento del loxoscelismo.A panoramic sight of epidemiological, clinical and experimental studies, referring to Loxosceles laeta and loxoscelism, carried out in 1955-1988, in Santiago, Chile is presented. Two-hundred and sixteen cases of loxosce lism were studied. The most relevant features were: 84.3% corresponded to cutaneous loxosce lism (CD and 15.7% to viscerocutaneous loxos celism (VCD; 73.6% ocurred in hot season; in 86

  2. The observed sensitivity of the global hydrological cycle to changes in surface temperature

    International Nuclear Information System (INIS)

    Arkin, Phillip A; Janowiak, John; Smith, Thomas M; Sapiano, Mathew R P

    2010-01-01

    Climate models project large changes in global surface temperature in coming decades that are expected to be accompanied by significant changes in the global hydrological cycle. Validation of model simulations is essential to support their use in decision making, but observing the elements of the hydrological cycle is challenging, and model-independent global data sets exist only for precipitation. We compute the sensitivity of the global hydrological cycle to changes in surface temperature using available global precipitation data sets and compare the results against the sensitivities derived from model simulations of 20th century climate. The implications of the results for the global climate observing system are discussed.

  3. Programa de viviendas experimentales en Móstoles, Comunidad de Madrid. España. (Preámbulo

    Directory of Open Access Journals (Sweden)

    Abad Carrascosa, Manuel

    1990-04-01

    Full Text Available This program consists of a total of 102 houses. They are situated in one of the housing estates in the General Urbanization Plan of the Móstoles Town Council (Town on outskirts of Madrid. The development of the prototypes of three different types of housing is to be studied with the aim of studying the experimental results of each one: — Progressive housing. — Housing with passive solar energy — Housing constructed on a basis of a special system in series. The three have the common aim of achieving finanical saving, but by different means: initial investment, saving in energy expenditure, the constructive system. The group of houses is about to be delivered into the hands of its users. We regret the incompleteness of the Information due to the lack of the most important results; the derivatives of its use and development, and Information of a social, economic, cultural, etc., character.

    Esta actuación consta de un total de 102 viviendas. Se encuentran localizadas en uno de los polígonos del Plan General de Urbanismo del Ayuntamiento de Móstoles (Población del extrarradio de Madrid. Se plantea el estudio y desarrollo, por separado, de tres prototipos diferentes de vivienda con el fin de poder estudiar los resultados experimentales de cada uno: — Viviendas progresivas. — Viviendas con energía solar pasiva. — Viviendas construidas a base de un sistema especial en serie. Los tres plantean el ahorro económico como fin común, pero desde distintas bases de partida: la inversión inicial; el ahorro energético, y el sistema constructivo. El conjunto se encuentra a punto de ser entregado a sus usuarios. Lamentamos lo incompleto de la información debido a la falta de sus resultados más importantes: los derivados de su uso y desarrollo; sociales, económicos, culturales, etcétera.

  4. Simulation of oat development cycle by photoperiod and temperature

    Directory of Open Access Journals (Sweden)

    Rubia D. Mantai

    Full Text Available ABSTRACT The simulation of oat development cycle can be used in the planning of agricultural practices. The aim of the study was to simulate and validate the duration of oat development cycle by photoperiod, temperature and coefficients of development of wheat for use in the WE-Streck model, considering different doses of N-fertilizer and systems of succession of high and low C/N ratio. The study was conducted in 2015 in a randomized block design with four replicates in a 4 x 2 factorial scheme, corresponding to N rates (0, 30, 60 and 120 kg ha-1 and oat cultivars (Barbarasul and Brisasul, respectively, in the soybean/oat and maize/oat systems. The duration of the stages from emergence to anthesis and from anthesis to maturation of oats was simulated in the WE-Streck model. The minimum, optimum and maximum temperatures that effectively simulate the oat development cycle were 4, 22 and 30 °C from emergence to anthesis and 15, 25 and 35 °C from anthesis to maturation, respectively. The intermediate-cycle oat development was efficiently simulated by the WE-Streck model using coefficients developed for wheat, with vegetative and reproductive cycles estimated at 89 and 43 days, respectively.

  5. Validation of simulation codes for future systems: motivations, approach, and the role of nuclear data

    International Nuclear Information System (INIS)

    Palmiotti, G.; Salvatores, M.; Aliberti, G.

    2007-01-01

    The validation of advanced simulation tools will still play a very significant role in several areas of reactor system analysis. This is the case of reactor physics and neutronics, where nuclear data uncertainties still play a crucial role for many core and fuel cycle parameters. The present paper gives a summary of validation motivations, objectives and approach. A validation effort is in particular necessary in the frame of advanced (e.g. Generation-IV or GNEP) reactors and associated fuel cycles assessment and design. Validation of simulation codes is complementary to the 'verification' process. In fact, 'verification' addresses the question 'are we solving the equations correctly' while validation addresses the question 'are we solving the correct equations with the correct parameters'. Verification implies comparisons with 'reference' equation solutions or with analytical solutions, when they exist. Most of what is called 'numerical validation' falls in this category. Validation strategies differ according to the relative weight of the methods and of the parameters that enter into the simulation tools. Most validation is based on experiments, and the field of neutronics where a 'robust' physics description model exists and which is function of 'input' parameters not fully known, will be the focus of this paper. In fact, in the case of reactor core, shielding and fuel cycle physics the model (theory) is well established (the Boltzmann and Bateman equations) and the parameters are the nuclear cross-sections, decay data etc. Two types of validation approaches can and have been used: (a) Mock-up experiments ('global' validation): need for a very close experimental simulation of a reference configuration. Bias factors cannot be extrapolated beyond reference configuration; (b) Use of 'clean', 'representative' integral experiments ('bias factor and adjustment' method). Allows to define bias factors, uncertainties and can be used for a wide range of applications. It

  6. Operating regimes of signaling cycles: statics, dynamics, and noise filtering.

    Directory of Open Access Journals (Sweden)

    Carlos Gomez-Uribe

    2007-12-01

    Full Text Available A ubiquitous building block of signaling pathways is a cycle of covalent modification (e.g., phosphorylation and dephosphorylation in MAPK cascades. Our paper explores the kind of information processing and filtering that can be accomplished by this simple biochemical circuit. Signaling cycles are particularly known for exhibiting a highly sigmoidal (ultrasensitive input-output characteristic in a certain steady-state regime. Here, we systematically study the cycle's steady-state behavior and its response to time-varying stimuli. We demonstrate that the cycle can actually operate in four different regimes, each with its specific input-output characteristics. These results are obtained using the total quasi-steady-state approximation, which is more generally valid than the typically used Michaelis-Menten approximation for enzymatic reactions. We invoke experimental data that suggest the possibility of signaling cycles operating in one of the new regimes. We then consider the cycle's dynamic behavior, which has so far been relatively neglected. We demonstrate that the intrinsic architecture of the cycles makes them act--in all four regimes--as tunable low-pass filters, filtering out high-frequency fluctuations or noise in signals and environmental cues. Moreover, the cutoff frequency can be adjusted by the cell. Numerical simulations show that our analytical results hold well even for noise of large amplitude. We suggest that noise filtering and tunability make signaling cycles versatile components of more elaborate cell-signaling pathways.

  7. Experimental studies on the X-radiation from a high-intensity annular discharge; Etudes experimentales sur le rayonnement X d'une decharge annulaire a forte intensite

    Energy Technology Data Exchange (ETDEWEB)

    Etievant, C [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1958-07-01

    Under certain conditions, a very penetrating X-radiation is emitted at the start of a stabilised annular discharge. A number of experimental observations have been made using a pyrex toroid filled with deuterium or argon. The value of the stabilising magnetic field and the pressure have a very important influence on the intensity of the X-radiation emitted. The placing of an obstacle such as a magnetic mirror at a point of the torus can prevent the acceleration of runaway electrons during successive revolutions, and X-ray emission disappears. (author) [French] Un rayonnement X tres penetrant est emis dans certaines conditions au debut d'une decharge annulaire stabilisee. Un certain nombre d'observations experimentales ont ete faites a l'aide d'un tore en pyrex rempli de deuterium ou d'argon. La valeur du champ magnetique stabilisateur et la pression jouent un role tres important sur l'intensite du rayonnement X emis. La disposition d'un obstacle tel qu'un miroir magnetique en un point du tore peut empecher l'acceleration d'electrons decouples au cours de revolutions successives et l'emission de rayonnement X disparait. (auteur)

  8. Validating a refractometer to evaluate immunoglobulin G concentration in Jersey colostrum and the effect of multiple freeze-thaw cycles on evaluating colostrum quality.

    Science.gov (United States)

    Morrill, K M; Robertson, K E; Spring, M M; Robinson, A L; Tyler, H D

    2015-01-01

    The objectives of this study were to (1) validate a method using refractometry to rapidly and accurately determine immunoglobulin (IgG) concentration in Jersey colostrum, (2) determine whether there should be different refractive index (nD) and %Brix cut points for Jersey colostrum, and (3) evaluate the effect of multiple freeze-thaw (FT) cycles on radial immunodiffusion (RID) and a digital refractometer to determine IgG concentration in Jersey colostrum. Samples (n=58; 3L) of colostrum were collected from a dairy in northwestern Iowa. Samples were analyzed within 2h of collection for IgG concentration by RID, %Brix, and nD by refractometer and an estimate of IgG by colostrometer. Samples were frozen, placed on dry ice, and transported to the laboratory at Iowa State University (Ames). Samples arrived frozen and were placed in a -20°C manual-defrost freezer until further analysis. On d 7 (1FT), d 14 (2FT), and 1yr (3FT) all samples were thawed, analyzed for IgG by RID, %Brix, nD by refractometer, and IgG estimate by colostrometer, and frozen until reanalysis at the next time point. Fresh colostrum had a mean (±SD) IgG concentration of 72.91 (±33.53) mg/mL, 21.24% (±4.43) Brix, and nD 1.3669 (±0.0074). Multiple FT cycles did affect IgG as determined by RID and colostrometer reading. The IgG concentrations were greater in fresh and 1FT samples as compared with 2FT and 3FT samples (72.91, 75.38, 67.20, and 67.31mg of IgG/mL, respectively). The colostrometer reading was lower in 1FT samples compared with fresh and 2FT samples. Multiple FT cycles had no effect on nD or %Brix reading. In fresh samples, IgG concentration was moderately correlated with nD (r=0.79), %Brix (r=0.79), and colostrometer reading (r=0.79). Diagnostic test characteristics using the recommended cut point of 1.35966 nD resulted in similar sensitivities for 1FT and 2 FT samples (94.87 and 94.74%, respectively). Cut points of 18 and 19% Brix resulted in the greatest sensitivities (92.31 and 84

  9. Expert system validation in prolog

    Science.gov (United States)

    Stock, Todd; Stachowitz, Rolf; Chang, Chin-Liang; Combs, Jacqueline

    1988-01-01

    An overview of the Expert System Validation Assistant (EVA) is being implemented in Prolog at the Lockheed AI Center. Prolog was chosen to facilitate rapid prototyping of the structure and logic checkers and since February 1987, we have implemented code to check for irrelevance, subsumption, duplication, deadends, unreachability, and cycles. The architecture chosen is extremely flexible and expansible, yet concise and complementary with the normal interactive style of Prolog. The foundation of the system is in the connection graph representation. Rules and facts are modeled as nodes in the graph and arcs indicate common patterns between rules. The basic activity of the validation system is then a traversal of the connection graph, searching for various patterns the system recognizes as erroneous. To aid in specifying these patterns, a metalanguage is developed, providing the user with the basic facilities required to reason about the expert system. Using the metalanguage, the user can, for example, give the Prolog inference engine the goal of finding inconsistent conclusions among the rules, and Prolog will search the graph intantiations which can match the definition of inconsistency. Examples of code for some of the checkers are provided and the algorithms explained. Technical highlights include automatic construction of a connection graph, demonstration of the use of metalanguage, the A* algorithm modified to detect all unique cycles, general-purpose stacks in Prolog, and a general-purpose database browser with pattern completion.

  10. Solar Sail Models and Test Measurements Correspondence for Validation Requirements Definition

    Science.gov (United States)

    Ewing, Anthony; Adams, Charles

    2004-01-01

    Solar sails are being developed as a mission-enabling technology in support of future NASA science missions. Current efforts have advanced solar sail technology sufficient to justify a flight validation program. A primary objective of this activity is to test and validate solar sail models that are currently under development so that they may be used with confidence in future science mission development (e.g., scalable to larger sails). Both system and model validation requirements must be defined early in the program to guide design cycles and to ensure that relevant and sufficient test data will be obtained to conduct model validation to the level required. A process of model identification, model input/output documentation, model sensitivity analyses, and test measurement correspondence is required so that decisions can be made to satisfy validation requirements within program constraints.

  11. Contribution to the methodology of safety evaluation - and licensing of reloading cycle for PWR type reactors

    International Nuclear Information System (INIS)

    Esteves, R.G.

    1981-01-01

    A simplified methodology for evaluating a reload safety cycle is presented. This methodology consists in selecting for each foreseen accident, the nuclear key reload safety parameters which determine the accident evolution. So, each key reload parameter is calculated and compared with its value for the first cycle. Those accidents, which have their key reload parameter bounded by the values of the first cycle do not need reanalise. Extension of the validity of this methodology when there exists change of fuel supplier is commented. (Author) [pt

  12. The Krebs Uric Acid Cycle: A Forgotten Krebs Cycle.

    Science.gov (United States)

    Salway, Jack G

    2018-05-25

    Hans Kornberg wrote a paper entitled 'Krebs and his trinity of cycles' commenting that every school biology student knows of the Krebs cycle, but few know that Krebs discovered two other cycles. These are (i) the ornithine cycle (urea cycle), (ii) the citric acid cycle (tricarboxylic acid or TCA cycle), and (iii) the glyoxylate cycle that was described by Krebs and Kornberg. Ironically, Kornberg, codiscoverer of the 'glyoxylate cycle', overlooked a fourth Krebs cycle - (iv) the uric acid cycle. Copyright © 2018 Elsevier Ltd. All rights reserved.

  13. Cell division cycle 20 overexpression predicts poor prognosis for patients with lung adenocarcinoma.

    Science.gov (United States)

    Shi, Run; Sun, Qi; Sun, Jing; Wang, Xin; Xia, Wenjie; Dong, Gaochao; Wang, Anpeng; Jiang, Feng; Xu, Lin

    2017-03-01

    The cell division cycle 20, a key component of spindle assembly checkpoint, is an essential activator of the anaphase-promoting complex. Aberrant expression of cell division cycle 20 has been detected in various human cancers. However, its clinical significance has never been deeply investigated in non-small-cell lung cancer. By analyzing The Cancer Genome Atlas database and using some certain online databases, we validated overexpression of cell division cycle 20 in both messenger RNA and protein levels, explored its clinical significance, and evaluated the prognostic role of cell division cycle 20 in non-small-cell lung cancer. Cell division cycle 20 expression was significantly correlated with sex (p = 0.003), histological classification (p overexpression of cell division cycle 20 was significantly associated with bigger primary tumor size (p = 0.0023), higher MKI67 level (r = 0.7618, p Overexpression of cell division cycle 20 is associated with poor prognosis in lung adenocarcinoma patients, and its overexpression can also be used to identify high-risk groups. In conclusion, cell division cycle 20 might serve as a potential biomarker for lung adenocarcinoma patients.

  14. Modelos experimentales para la evaluación de la acción cicatrizante de medicamentos

    Directory of Open Access Journals (Sweden)

    Raimara González Escobar

    2002-12-01

    Full Text Available Los intentos del organismo para reparar las lesiones inducidas por agresiones locales comienzan muy precozmente en el proceso de la inflamación, y finalmente concluyen con la reparación y sustitución de las células lesionadas por células sanas. El proceso de cicatrización de una herida en la piel involucra la compleja interacción de muchos tipos de células y ocurre como una cascada secuencial de procesos solapados e íntimamente relacionados. Existen varios modelos farmacológicos experimentales que permiten evaluar la acción cicatrizante de un principio activo, profundizando en los eventos específicos de la cicatrización. En este trabajo se presentarán los detalles de algunos de estos modelos, los cuales son: modelo de lesión inducida por quemadura en curieles, modelo de 6 heridas asépticas en cerdos, promoción de cicatrización por segunda intención en ratas y modelo para predecir la distribución de un medicamento aplicado tópicamente en heridas. Estos ensayos permiten el estudio de múltiples elementos histológicos, bioquímicos, celulares y clínicos, característicos del proceso de cicatrización.The attempts of the organism to repair injuries induced by local aggressions begin very early in the inflammation process and conclude finally with the reparation and substitution of those cells damaged by sound cells. The healing process of a skin wound involves the complex interaction of many types of cells and a sequence of sneaky and closely related processes take place. There are various pharmacological experimental models allowing to evaluate the healing action of an active principle and to go deep into the specific healing events. Details are given in this paper about the following models: model of injury induced by burn in guinea pigs, model of 6 aseptic wounds in pigs, promotion of healing by second intention in rats and a model to predict the distribution of a drug topically applied in wounds. These assays make possible

  15. Development of a procedure for estimating the high cycle fatigue strength of some high temperature structural alloys

    International Nuclear Information System (INIS)

    Soo, P.; Chow, J.G.Y.

    1979-01-01

    The generation of strain controlled fatigue data, for the standard strain rate of 4 x 10 -3 sec -1 , presents a problem when the cycles to failure exceed 10 5 because of the prohibitively long test times involved. In an attempt to circumvent this difficulty an evaluation has been made of a test procedure involving a fast cycling rate (40 Hz) and load controlled conditions. The validity of this procedure for extending current fatigue curves from 10 5 to 10 8 cycles and beyond, hinges upon the selection of an appropriate effective strain value, since the strain usually changes rapidly during the early stage of fatigue. Results from annealed 2 1/4 Cr-1 Mo, type 304 stainless steel, Incoloy 800H and Hastelloy X, tested over a wide range of temperatures, show that the strain measured N/sub f/2 is a reasonable estimate since it gives an excellent correlation between the strain and load controlled tests in the 10 5 cycle range where the data overlap. It seems clear that the differences in cycling rate and early stress-strain history for the two tests do not significantly affect the correlation. It may, therefore, be concluded that such load control test procedures may be used as a valid fast way for extending currently available fatigue curves from 10 5 to 10 8 cycles, and beyond

  16. Cycle energy control of magnetorheological dampers on cables

    International Nuclear Information System (INIS)

    Weber, F; Feltrin, G; Motavalli, M; Distl, H

    2009-01-01

    The dissipated cycle energy of magnetorheological (MR) dampers operated at constant current results from controllable hysteretic damping and from almost current independent, small viscous damping. Thus, the emulation of Coulomb friction and linear viscous damping necessitates current modulation during one vibration cycle and therefore current drivers. To avoid this drawback, a cycle energy control (CEC) approach is presented which controls the hysteretic MR damper part such that the total MR damper energy equals the energy of optimal linear viscous damping by constant current during one cycle. The excited higher modes due to the hysteretic damping part are partially damped by the MR damper viscous part. Simulations show that CEC copes better with damper force dynamics and constraints than emulated linear viscous damping due to the slow control force dynamics of CEC which are given by cable amplitude dynamics. It is demonstrated that CEC of MR dampers with viscosity of approximately 4.65% of the optimal modal viscosity performs better than optimal linear viscous damping. The reason is that this damper viscosity represents an optimal compromise between maximum energy spillover to higher modes due to the controllable hysteretic part which produces more cable damping and maximum viscous damping of these higher modes. Damping tests on a cable with an MR damper validate the CEC approach

  17. A signature-based method for indexing cell cycle phase distribution from microarray profiles

    Directory of Open Access Journals (Sweden)

    Mizuno Hideaki

    2009-03-01

    Full Text Available Abstract Background The cell cycle machinery interprets oncogenic signals and reflects the biology of cancers. To date, various methods for cell cycle phase estimation such as mitotic index, S phase fraction, and immunohistochemistry have provided valuable information on cancers (e.g. proliferation rate. However, those methods rely on one or few measurements and the scope of the information is limited. There is a need for more systematic cell cycle analysis methods. Results We developed a signature-based method for indexing cell cycle phase distribution from microarray profiles under consideration of cycling and non-cycling cells. A cell cycle signature masterset, composed of genes which express preferentially in cycling cells and in a cell cycle-regulated manner, was created to index the proportion of cycling cells in the sample. Cell cycle signature subsets, composed of genes whose expressions peak at specific stages of the cell cycle, were also created to index the proportion of cells in the corresponding stages. The method was validated using cell cycle datasets and quiescence-induced cell datasets. Analyses of a mouse tumor model dataset and human breast cancer datasets revealed variations in the proportion of cycling cells. When the influence of non-cycling cells was taken into account, "buried" cell cycle phase distributions were depicted that were oncogenic-event specific in the mouse tumor model dataset and were associated with patients' prognosis in the human breast cancer datasets. Conclusion The signature-based cell cycle analysis method presented in this report, would potentially be of value for cancer characterization and diagnostics.

  18. Verification and validation of COBRA-SFS transient analysis capability

    International Nuclear Information System (INIS)

    Rector, D.R.; Michener, T.E.; Cuta, J.M.

    1998-05-01

    This report provides documentation of the verification and validation testing of the transient capability in the COBRA-SFS code, and is organized into three main sections. The primary documentation of the code was published in September 1995, with the release of COBRA-SFS, Cycle 2. The validation and verification supporting the release and licensing of COBRA-SFS was based solely on steady-state applications, even though the appropriate transient terms have been included in the conservation equations from the first cycle. Section 2.0, COBRA-SFS Code Description, presents a capsule description of the code, and a summary of the conservation equations solved to obtain the flow and temperature fields within a cask or assembly model. This section repeats in abbreviated form the code description presented in the primary documentation (Michener et al. 1995), and is meant to serve as a quick reference, rather than independent documentation of all code features and capabilities. Section 3.0, Transient Capability Verification, presents a set of comparisons between code calculations and analytical solutions for selected heat transfer and fluid flow problems. Section 4.0, Transient Capability Validation, presents comparisons between code calculations and experimental data obtained in spent fuel storage cask tests. Based on the comparisons presented in Sections 2.0 and 3.0, conclusions and recommendations for application of COBRA-SFS to transient analysis are presented in Section 5.0

  19. Transient modeling of an air conditioner with a rapid cycling compressor and multi-indoor units

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Wei-Jiang [Institute of Refrigeration and Cryogenics, Shanghai Jiaotong University, Shanghai 200240 (China); Zhang, Chun-Lu [College of Mechanical Engineering, Tongji University, 4800 Cao An Highway, Shanghai 201804 (China)

    2011-01-15

    Rapid cycling the compressor is an alternative of the variable speed compressor to modulate the capacity of refrigeration systems for the purpose of energy saving at part-load conditions. The multi-evaporator air conditioner combined with the rapid cycling compressor brings difficulties in control design because of the sophisticated system physics and dynamics. In this paper the transient model of a multi-split air conditioner with a digital scroll compressor is developed for predicting the system transients under performance modulations. The predicted cycling dynamics are in good agreement with the experimental data. Based on the validated model, the impact of compressor idle power and cycle period to the part load performance is discussed. (author)

  20. Transient modeling of an air conditioner with a rapid cycling compressor and multi-indoor units

    Energy Technology Data Exchange (ETDEWEB)

    Zhang Weijiang [Institute of Refrigeration and Cryogenics, Shanghai Jiaotong University, Shanghai 200240 (China); Zhang Chunlu, E-mail: chunlu.zhang@carrier.utc.co [College of Mechanical Engineering, Tongji University, 4800 Cao An Highway, Shanghai 201804 (China)

    2011-01-15

    Rapid cycling the compressor is an alternative of the variable speed compressor to modulate the capacity of refrigeration systems for the purpose of energy saving at part-load conditions. The multi-evaporator air conditioner combined with the rapid cycling compressor brings difficulties in control design because of the sophisticated system physics and dynamics. In this paper the transient model of a multi-split air conditioner with a digital scroll compressor is developed for predicting the system transients under performance modulations. The predicted cycling dynamics are in good agreement with the experimental data. Based on the validated model, the impact of compressor idle power and cycle period to the part load performance is discussed.

  1. Transient modeling of an air conditioner with a rapid cycling compressor and multi-indoor units

    International Nuclear Information System (INIS)

    Zhang Weijiang; Zhang Chunlu

    2011-01-01

    Rapid cycling the compressor is an alternative of the variable speed compressor to modulate the capacity of refrigeration systems for the purpose of energy saving at part-load conditions. The multi-evaporator air conditioner combined with the rapid cycling compressor brings difficulties in control design because of the sophisticated system physics and dynamics. In this paper the transient model of a multi-split air conditioner with a digital scroll compressor is developed for predicting the system transients under performance modulations. The predicted cycling dynamics are in good agreement with the experimental data. Based on the validated model, the impact of compressor idle power and cycle period to the part load performance is discussed.

  2. Endogenous protein "barcode" for data validation and normalization in quantitative MS analysis.

    Science.gov (United States)

    Lee, Wooram; Lazar, Iulia M

    2014-07-01

    Quantitative proteomic experiments with mass spectrometry detection are typically conducted by using stable isotope labeling and label-free quantitation approaches. Proteins with housekeeping functions and stable expression level such actin, tubulin, and glyceraldehyde-3-phosphate dehydrogenase are frequently used as endogenous controls. Recent studies have shown that the expression level of such common housekeeping proteins is, in fact, dependent on various factors such as cell type, cell cycle, or disease status and can change in response to a biochemical stimulation. The interference of such phenomena can, therefore, substantially compromise their use for data validation, alter the interpretation of results, and lead to erroneous conclusions. In this work, we advance the concept of a protein "barcode" for data normalization and validation in quantitative proteomic experiments. The barcode comprises a novel set of proteins that was generated from cell cycle experiments performed with MCF7, an estrogen receptor positive breast cancer cell line, and MCF10A, a nontumorigenic immortalized breast cell line. The protein set was selected from a list of ~3700 proteins identified in different cellular subfractions and cell cycle stages of MCF7/MCF10A cells, based on the stability of spectral count data generated with an LTQ ion trap mass spectrometer. A total of 11 proteins qualified as endogenous standards for the nuclear and 62 for the cytoplasmic barcode, respectively. The validation of the protein sets was performed with a complementary SKBR3/Her2+ cell line.

  3. A Comparison of Single-Cycle Versus Multiple-Cycle Proof Testing Strategies

    Science.gov (United States)

    McClung, R. C.; Chell, G. G.; Millwater, H. R.; Russell, D. A.; Millwater, H. R.

    1999-01-01

    Single-cycle and multiple-cycle proof testing (SCPT and MCPT) strategies for reusable aerospace propulsion system components are critically evaluated and compared from a rigorous elastic-plastic fracture mechanics perspective. Earlier MCPT studies are briefly reviewed. New J-integral estimation methods for semielliptical surface cracks and cracks at notches are derived and validated. Engineering methods are developed to characterize crack growth rates during elastic-plastic fatigue crack growth (FCG) and the tear-fatigue interaction near instability. Surface crack growth experiments are conducted with Inconel 718 to characterize tearing resistance, FCG under small-scale yielding and elastic-plastic conditions, and crack growth during simulated MCPT. Fractography and acoustic emission studies provide additional insight. The relative merits of SCPT and MCPT are directly compared using a probabilistic analysis linked with an elastic-plastic crack growth computer code. The conditional probability of failure in service is computed for a population of components that have survived a previous proof test, based on an assumed distribution of initial crack depths. Parameter studies investigate the influence of proof factor, tearing resistance, crack shape, initial crack depth distribution, and notches on the MCPT versus SCPT comparison. The parameter studies provide a rational basis to formulate conclusions about the relative advantages and disadvantages of SCPT and MCPT. Practical engineering guidelines are proposed to help select the optimum proof test protocol in a given application.

  4. Transient thermal model of passenger car's cabin and implementation to saturation cycle with alternative working fluids

    International Nuclear Information System (INIS)

    Lee, Hoseong; Hwang, Yunho; Song, Ilguk; Jang, Kilsang

    2015-01-01

    A transient thermal model of a passenger car's cabin is developed to investigate the dynamic behavior of cabin thermal conditions. The model is developed based on a lumped-parameter model and solved using integral methods. Solar radiation, engine heat through the firewall, and engine heat to the air ducts are all considered. Using the thermal model, transient temperature profiles of the interior mass and cabin air are obtained. This model is used to investigate the transient behavior of the cabin under various operating conditions: the recirculation mode in the idling state, the fresh air mode in the idling state, the recirculation mode in the driving state, and fresh air mode in the driving state. The developed model is validated by comparing with experimental data and is within 5% of deviation. The validated model is then applied for evaluating the mobile air conditioning system's design. The study found that a saturation cycle concept (four-stage cycle with two-phase refrigerant injection) could improve the system efficiency by 23.9% and reduce the power consumption by 19.3%. Lastly, several alternative refrigerants are applied and their performance is discussed. When the saturation cycle concept is applied, R1234yf MAC (mobile air conditioning) shows the largest COP (coefficient of performance) improvement and power consumption reduction. - Highlights: • The transient thermal model of the passenger car cabin is developed. • The developed model is validated with experimental data and showed 5% deviation. • Saturation cycle concept is applied to the developed cabin model. • There is 24% COP improvement by applying the saturation cycle concept. • R1234yf showed the highest potential when it is applied to the saturation cycle.

  5. Bayesian risk-based decision method for model validation under uncertainty

    International Nuclear Information System (INIS)

    Jiang Xiaomo; Mahadevan, Sankaran

    2007-01-01

    This paper develops a decision-making methodology for computational model validation, considering the risk of using the current model, data support for the current model, and cost of acquiring new information to improve the model. A Bayesian decision theory-based method is developed for this purpose, using a likelihood ratio as the validation metric for model assessment. An expected risk or cost function is defined as a function of the decision costs, and the likelihood and prior of each hypothesis. The risk is minimized through correctly assigning experimental data to two decision regions based on the comparison of the likelihood ratio with a decision threshold. A Bayesian validation metric is derived based on the risk minimization criterion. Two types of validation tests are considered: pass/fail tests and system response value measurement tests. The methodology is illustrated for the validation of reliability prediction models in a tension bar and an engine blade subjected to high cycle fatigue. The proposed method can effectively integrate optimal experimental design into model validation to simultaneously reduce the cost and improve the accuracy of reliability model assessment

  6. Improving Life-Cycle Cost Management of Spacecraft Missions

    Science.gov (United States)

    Clardy, Dennon

    2010-01-01

    This presentation will explore the results of a recent NASA Life-Cycle Cost study and how project managers can use the findings and recommendations to improve planning and coordination early in the formulation cycle and avoid common pitfalls resulting in cost overruns. The typical NASA space science mission will exceed both the initial estimated and the confirmed life-cycle costs by the end of the mission. In a fixed-budget environment, these overruns translate to delays in starting or launching future missions, or in the worst case can lead to cancelled missions. Some of these overruns are due to issues outside the control of the project; others are due to the unpredictable problems (unknown unknowns) that can affect any development project. However, a recent study of life-cycle cost growth by the Discovery and New Frontiers Program Office identified a number of areas that are within the scope of project management to address. The study also found that the majority of the underlying causes for cost overruns are embedded in the project approach during the formulation and early design phases, but the actual impacts typically are not experienced until late in the project life cycle. Thus, project management focus in key areas such as integrated schedule development, management structure and contractor communications processes, heritage and technology assumptions, and operations planning, can be used to validate initial cost assumptions and set in place management processes to avoid the common pitfalls resulting in cost overruns.

  7. The ARTEMIS European driving cycles for measuring car pollutant emissions.

    Science.gov (United States)

    André, Michel

    2004-12-01

    In the past 10 years, various work has been undertaken to collect data on the actual driving of European cars and to derive representative real-world driving cycles. A compilation and synthesis of this work is provided in this paper. In the frame of the European research project: ARTEMIS, this work has been considered to derive a set of reference driving cycles. The main objectives were as follows: to derive a common set of reference real-world driving cycles to be used in the frame of the ARTEMIS project but also in the frame of on-going national campaigns of pollutant emission measurements, to ensure the compatibility and integration of all the resulting emission data in the European systems of emission inventory; to ensure and validate the representativity of the database and driving cycles by comparing and taking into account all the available data regarding driving conditions; to include in three real-world driving cycles (urban, rural road and motorway) the diversity of the observed driving conditions, within sub-cycles allowing a disaggregation of the emissions according to more specific driving conditions (congested and free-flow urban). Such driving cycles present a real advantage as they are derived from a large database, using a methodology that was widely discussed and approved. In the main, these ARTEMIS driving cycles were designed using the available data, and the method of analysis was based to some extent on previous work. Specific steps were implemented. The study includes characterisation of driving conditions and vehicle uses. Starting conditions and gearbox use are also taken into account.

  8. Underwater behaviour of bitumen coated radioactive wastes: experimental validation of the Colonbo degradation model; Comportement sous eau des dechets radioactifs bitumes: validation experimentale du modele de degradation Colonbo

    Energy Technology Data Exchange (ETDEWEB)

    Gwinner, B

    2004-03-01

    In the release scenario considered for geologic repository, water is thought to be the main aggressive agent with regards to bituminized radioactive waste (composed in general of 60 weight % of bitumen, 40% of soluble/insoluble salts and a few ppm of radionuclides). Since liquid water can diffuse in pure bitumen, leaching of bituminized waste results in the dissolution of the most soluble salts and leads to the development of a more or less concentrated saline solution-filled pore structure (called permeable layer). In consequence of the generation of a porous layer in the bituminized waste, leaching of salts and radionuclides can then take place. Research performed at the Atomic Energy Commission (CEA) aims therefore at understanding the consequences of ground-water immersion on the transport properties and radionuclides leaching of bituminized waste materials. To this end, a constitutive model (called COLONBO) which describes mathematically the leaching of bituminized waste has been developed. The COLONBO model is based on the following assumptions: 1. Water and dissolved salts migrate in the permeable layer according to Fick's first law. The diffusion of water and salts are quantified by effective diffusion coefficients which are unknown. 2. The mechanical properties of the bitumen matrix are not considered during leaching (free swelling). Up to now, the COLONBO model has been used only to model experimental water uptake and salt leach curves, leading (theoretical) estimates of the effective diffusion coefficients of water and salts in the permeable layer. The aim of this work was to validate experimentally the numerical results obtained with the COLONBO model. First, the correspondence between experimental and simulated water uptake and salt leach rates obtained on various bituminized waste materials is checked, leading estimates of the effective diffusion coefficients of water and salts in the permeable layer. Second, the evolution of the thickness and of

  9. Architecture and inherent robustness of a bacterial cell-cycle control system.

    Science.gov (United States)

    Shen, Xiling; Collier, Justine; Dill, David; Shapiro, Lucy; Horowitz, Mark; McAdams, Harley H

    2008-08-12

    A closed-loop control system drives progression of the coupled stalked and swarmer cell cycles of the bacterium Caulobacter crescentus in a near-mechanical step-like fashion. The cell-cycle control has a cyclical genetic circuit composed of four regulatory proteins with tight coupling to processive chromosome replication and cell division subsystems. We report a hybrid simulation of the coupled cell-cycle control system, including asymmetric cell division and responses to external starvation signals, that replicates mRNA and protein concentration patterns and is consistent with observed mutant phenotypes. An asynchronous sequential digital circuit model equivalent to the validated simulation model was created. Formal model-checking analysis of the digital circuit showed that the cell-cycle control is robust to intrinsic stochastic variations in reaction rates and nutrient supply, and that it reliably stops and restarts to accommodate nutrient starvation. Model checking also showed that mechanisms involving methylation-state changes in regulatory promoter regions during DNA replication increase the robustness of the cell-cycle control. The hybrid cell-cycle simulation implementation is inherently extensible and provides a promising approach for development of whole-cell behavioral models that can replicate the observed functionality of the cell and its responses to changing environmental conditions.

  10. Medium- and Heavy-Duty Vehicle Duty Cycles for Electric Powertrains

    Energy Technology Data Exchange (ETDEWEB)

    Kelly, Kenneth; Bennion, Kevin; Miller, Eric; Prohaska, Bob

    2016-03-02

    NREL's Fleet Test and Evaluation group has extensive in-use vehicle data demonstrating the importance of understanding the vocational duty cycle for appropriate sizing of electric vehicle (EV) and power electronics components for medium- and heavy-duty EV applications. This presentation includes an overview of recent EV fleet evaluation projects that have valuable in-use data that can be leveraged for sub-system research, analysis, and validation. Peak power and power distribution data from in-field EVs are presented for four different vocations, including class 3 delivery vans, class 6 delivery trucks, class 8 transit buses, and class 8 port drayage trucks, demonstrating the impacts of duty cycle on performance requirements.

  11. Junction temperature estimation for an advanced active power cycling test

    DEFF Research Database (Denmark)

    Choi, Uimin; Blaabjerg, Frede; Jørgensen, S.

    2015-01-01

    estimation method using on-state VCE for an advanced active power cycling test is proposed. The concept of the advanced power cycling test is explained first. Afterwards the junction temperature estimation method using on-state VCE and current is presented. Further, the method to improve the accuracy...... of the maximum junction temperature estimation is also proposed. Finally, the validity and effectiveness of the proposed method is confirmed by experimental results.......On-state collector-emitter voltage (VCE) is a good indicator to determine the wear-out condition of power device modules. Further, it is a one of the Temperature Sensitive Electrical Parameters (TSEPs) and thus can be used for junction temperature estimation. In this paper, the junction temperature...

  12. Reliability and validity of the transport and physical activity questionnaire (TPAQ) for assessing physical activity behaviour.

    Science.gov (United States)

    Adams, Emma J; Goad, Mary; Sahlqvist, Shannon; Bull, Fiona C; Cooper, Ashley R; Ogilvie, David

    2014-01-01

    No current validated survey instrument allows a comprehensive assessment of both physical activity and travel behaviours for use in interdisciplinary research on walking and cycling. This study reports on the test-retest reliability and validity of physical activity measures in the transport and physical activity questionnaire (TPAQ). The TPAQ assesses time spent in different domains of physical activity and using different modes of transport for five journey purposes. Test-retest reliability of eight physical activity summary variables was assessed using intra-class correlation coefficients (ICC) and Kappa scores for continuous and categorical variables respectively. In a separate study, the validity of three survey-reported physical activity summary variables was assessed by computing Spearman correlation coefficients using accelerometer-derived reference measures. The Bland-Altman technique was used to determine the absolute validity of survey-reported time spent in moderate-to-vigorous physical activity (MVPA). In the reliability study, ICC for time spent in different domains of physical activity ranged from fair to substantial for walking for transport (ICC = 0.59), cycling for transport (ICC = 0.61), walking for recreation (ICC = 0.48), cycling for recreation (ICC = 0.35), moderate leisure-time physical activity (ICC = 0.47), vigorous leisure-time physical activity (ICC = 0.63), and total physical activity (ICC = 0.56). The proportion of participants estimated to meet physical activity guidelines showed acceptable reliability (k = 0.60). In the validity study, comparison of survey-reported and accelerometer-derived time spent in physical activity showed strong agreement for vigorous physical activity (r = 0.72, ptravel behaviours and may be suitable for wider use. Its physical activity summary measures have comparable reliability and validity to those of similar existing questionnaires.

  13. Energy expenditure, aerodynamics and medical problems in cycling. An update.

    Science.gov (United States)

    Faria, I E

    1992-07-01

    The cyclist's ability to maintain an extremely high rate of energy expenditure for long durations at a high economy of effort is dependent upon such factors as the individual's anaerobic threshold, muscle fibre type, muscle myoglobin concentration, muscle capillary density and certain anthropometric dimensions. Although laboratory tests have had some success predicting cycling potential, their validity has yet to be established for trained cyclists. Even in analysing the forces producing propulsive torque, cycling effectiveness cannot be based solely on the orientation of applied forces. Innovations of shoe and pedal design continue to have a positive influence on the biomechanics of pedalling. Although muscle involvement during a complete pedal revolution may be similar, economical pedalling rate appears to differ significantly between the novice and racing cyclist. This difference emanates, perhaps, from long term adaptation. Air resistance is by far the greatest retarding force affecting cycling. The aerodynamics of the rider and the bicycle and its components are major contributors to cycling economy. Correct body posture and spacing between riders can significantly enhance speed and efficiency. Acute and chronic responses to cycling and training are complex. To protect the safety and health of the cyclist there must be close monitoring and cooperation between the cyclist, coach, exercise scientist and physician.

  14. Alternative ORC bottoming cycles FOR combined cycle power plants

    International Nuclear Information System (INIS)

    Chacartegui, R.; Sanchez, D.; Munoz, J.M.; Sanchez, T.

    2009-01-01

    In this work, low temperature Organic Rankine Cycles are studied as bottoming cycle in medium and large scale combined cycle power plants. The analysis aims to show the interest of using these alternative cycles with high efficiency heavy duty gas turbines, for example recuperative gas turbines with lower gas turbine exhaust temperatures than in conventional combined cycle gas turbines. The following organic fluids have been considered: R113, R245, isobutene, toluene, cyclohexane and isopentane. Competitive results have been obtained for toluene and cyclohexane ORC combined cycles, with reasonably high global efficiencies. The paper is structured in four main parts. A review of combined cycle and ORC cycle technologies is presented, followed by a thermodynamic analysis of combined cycles with commercial gas turbines and ORC low temperature bottoming cycles. Then, a parametric optimization of an ORC combined cycle plant is performed in order to achieve a better integration between these two technologies. Finally, some economic considerations related to the use of ORC in combined cycles are discussed.

  15. Psychometric validation of the dysmenorrhea daily diary (DysDD): a patient-reported outcome for dysmenorrhea.

    Science.gov (United States)

    Nguyen, Allison M; Arbuckle, Rob; Korver, Tjeerd; Chen, Fang; Taylor, Beverley; Turnbull, Alice; Norquist, Josephine M

    2017-08-01

    The objective of this study was to evaluate the psychometric properties of the Dysmenorrhea Daily Diary (DysDD), an electronic patient-reported outcome, in a sample of 355 women with primary dysmenorrhea enrolled in a phase IIb, multicenter, randomized, partially blinded, placebo-controlled trial for treatment of dysmenorrhea. Subjects completed the DysDD over three menstrual cycles, one pre-treatment baseline cycle and two treatment cycles. The DysDD was administered alongside the Menstrual Distress Questionnaire (MDQ), the Short-Form 36 Version 2.0 (SF-36v2), and a Global Assessment of Change (GAC). Item response distributions, test-retest reliability, concurrent and known groups validity, responsiveness, and minimally important difference (MID) were evaluated for the DysDD. As expected, item response distributions varied throughout the menstrual period for all items, with the response scales fully utilized. Within-cycle test-retest reliability was adequate (weighted kappa: 0.5-0.7), although between-cycle test-retest was poor (weighted kappa: 0.1-0.5), most likely due to the highly variable nature of dysmenorrhea between cycles rather than limitations of the measure. Correlations with the MDQ and SF-36v2 were low-moderate, but in the predicted direction, supporting concurrent validity. There were significant differences in DysDD scores across severity groups based on pain medication use. The DysDD was responsive to changes in patients' dysmenorrhea with significantly different changes in scores between change groups (p dysmenorrhea.

  16. Experimental determination of the back scattering factor in X-ray microanalysis; Determination experimentale du facteur de retro-diffusion en microanalyse par emission X

    Energy Technology Data Exchange (ETDEWEB)

    Derian, J C [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1966-06-01

    This paper describes the first experimental method which has fixed the relative value of the X-ray loss by electron back scattering. Measurements have been performed, using gold, copper and aluminium specimens and accelerating voltages from 10 to 30 kV. Our experimental results, although higher than back scattering factor values calculated before, agree fairly well with those obtained by a Monte-Carlo calculation, using recent experimental measurement on thin films. The higher values obtained here, show that the compensation between deceleration and back scattering effects is better: the discrepancy from a linearity law is then probably weaker than it has been generally shown previously. (author) [French] Le memoire decrit la premiere methode experimentale ayant permis de determiner l'importance relative de la fraction du rayonnement X perdue par retrodiffusion des electrons. Les mesures ont porte sur l'or, le cuivre et l'aluminium entre 10 et 30 kV. Les resultats, sensiblement superieurs aux estimations anterieures, sont en bon accord avec ceux deduits, par la methode de Monte-Carlo, des recentes mesures sur les lames minces. Les valeurs plus elevees du facteur de retrodiffusion mises ainsi en evidence, conduisent a une meilleure compensation entre les effets de ralentissement et de retrodiffusion: l'ecart a une simple loi de proportionnalite par effet de difference de nombre atomique est ainsi probablement plus faible qu'on ne le pensait generalement jusqu'ici. (auteur)

  17. Cycling infrastructure for reducing cycling injuries in cyclists.

    Science.gov (United States)

    Mulvaney, Caroline A; Smith, Sherie; Watson, Michael C; Parkin, John; Coupland, Carol; Miller, Philip; Kendrick, Denise; McClintock, Hugh

    2015-12-10

    Cycling is an attractive form of transport. It is beneficial to the individual as a form of physical activity that may fit more readily into an individual's daily routine, such as for cycling to work and to the shops, than other physical activities such as visiting a gym. Cycling is also beneficial to the wider community and the environment as a result of fewer motorised journeys. Cyclists are seen as vulnerable road users who are frequently in close proximity to larger and faster motorised vehicles. Cycling infrastructure aims to make cycling both more convenient and safer for cyclists. This review is needed to guide transport planning. To:1. evaluate the effects of different types of cycling infrastructure on reducing cycling injuries in cyclists, by type of infrastructure;2. evaluate the effects of cycling infrastructure on reducing the severity of cycling injuries in cyclists;3. evaluate the effects of cycling infrastructure on reducing cycling injuries in cyclists with respect to age, sex and social group. We ran the most recent search on 2nd March 2015. We searched the Cochrane Injuries Group Specialised Register, CENTRAL (The Cochrane Library), MEDLINE (OvidSP), Embase Classic + Embase(OvidSP), PubMed and 10 other databases. We searched websites, handsearched conference proceedings, screened reference lists of included studies and previously published reviews and contacted relevant organisations. We included randomised controlled trials, cluster randomised controlled trials, controlled before-after studies, and interrupted time series studies which evaluated the effect of cycling infrastructure (such as cycle lanes, tracks or paths, speed management, roundabout design) on cyclist injury or collision rates. Studies had to include a comparator, that is, either no infrastructure or a different type of infrastructure. We excluded studies that assessed collisions that occurred as a result of competitive cycling. Two review authors examined the titles and

  18. Numerical and Engine Cycle Analyses of a Pulse Laser Ramjet Vehicle

    Science.gov (United States)

    Katsurayama, Hiroshi; Komurasaki, Kimiya; Momozawa, Ai; Arakawa, Yoshihiro

    A preliminary feasibility study of a laser ramjet SSTO has been conducted using engine cycle analysis. Although a large amount of laser energy is lost due to chemically frozen flow at high altitudes, the laser ramjet SSTO was found to be feasible with 100 MW laser power for 100 kg vehicle mass and 1 m2 vehicle cross-section area. Obtained momentum coupling coefficient, Cm, was validated by means of CFD. As a result, the engine cycle analysis was under-estimating Cm. This would be because of the strong unsteady energy input in the actual heating process and the spatially localized pressure on the afterbody.

  19. Effect of cyclic plastic pre-strain on low cycle fatigue life

    International Nuclear Information System (INIS)

    Kanno, Satoshi; Nakane, Motoki; Yorikawa, Morio; Takagi, Yoshio

    2010-01-01

    In order to evaluate structural integrity of nuclear components subjected large seismic load which produce locally plastic strain, low cycle fatigue life was examined using cyclic plastic pre-strained materials of austenitic steel (SUS316, SUS316L, SUS304TP: JIS (Japanese Industrial Standards)) and ferritic steel (SFVQ1A, STS480, STPT410, SFVC2B, SS400: JIS). It was not found that cyclic plastic pre-strain up to range of 16%, 2.5 times affected on low cycle fatigue life. The validity of existing procedure of fatigue life estimation based on usage factor was confirmed when large seismic load brought nuclear materials cyclic plastic strain. (author)

  20. Proceso de gasificación de biomasa: una revisión de estudios teórico- experimentales

    Directory of Open Access Journals (Sweden)

    Juan Pérez

    2010-01-01

    Full Text Available La situación energética y medioambiental mundial hace que la generación de energía mediante sistemas basados en energías renovables tome cada vez una mayor relevancia. Estos sistemas tienen una doble ventaja ya que posibilitan la diversificación energética y reducen la dependencia del petróleo a la vez que se disminuyen las emisiones globales de CO2. La biomasa es uno de los recursos energéticos con mayor potencial tanto en países desarrollados como emergentes pero sigue sin sufrir el desarrollo esperado. La gasificación de biomasa es uno de los sistemas con gran potencial ya que permite la generación tanto de energía térmica como eléctrica, mediante tecnologías de bajo costo como los gasificadores de lecho fijo (potencias medias- bajas, o reactores de lecho fluidizado con tecnología más exigente y con mayor capacidad de generación. La transformación de la biomasa en un combustible gaseoso, aprovechable en motores de combustión interna alternativos o en turbinas de gas como combustible, exige que la biomasa atraviese varios procesos termoquímicos, compuestos por reacciones endotérmicas (secado, devolatilización y reducción y exotérmicas (oxidación de volátiles y carbón. La selección de un gasificador requiere conocer las propiedades de la biomasa, mientras que el diseño del mismo exige conocer el fenómeno termoquímico por completo. El objetivo de este trabajo es presentar una revisión actualizada de los diferentes planteamientos tanto teóricos como experimentales desarrollados para estudiar el proceso de gasificación de biomasa, tanto en lecho fijo como en lecho fluidizado, con miras a diseñar gasificadores de biomasa.

  1. Validity and Reliability of the Cycleops Hammer Cycle Ergometer.

    Science.gov (United States)

    Lillo-Bevia, José R; Pallarés, Jesús G

    2017-11-28

    To validate the new drive indoor trainer Hammer designed by Cycleops®. Eleven cyclists performed 44 randomized and counterbalanced graded exercise tests (100-500W), at 70, 85 and 100 rev.min -1 cadences, in seated and standing positions, on 3 different Hammer units, while a scientific SRM system continuously recorded cadence and power output data. No significant differences were detected between the three Hammer devices and the SRM for any workload, cadence, or pedalling condition (P value between 1.00 and 0.350), except for some minor differences (P 0.03 and 0.04) found in the Hammer 1 at low workloads, and for Hammer 2 and 3 at high workloads, all in seated position. Strong ICCs were found between the power output values recorded by the Hammers and the SRM (≥0.996; P=0.001), independently from the cadence condition and seated position. Bland-Altman analysis revealed low Bias (-5.5-3.8) and low SD of Bias (2.5-5.3) for all testing conditions, except marginal values found for the Hammer 1 at high cadences and seated position (9.6±6.6). High absolute reliability values were detected for the 3 Hammers (150-500W; CVreliable device to drive and measure power output in cyclists, providing an alternative to larger and more expensive laboratory ergometers, and allowing cyclists to use their own bicycle.

  2. Datos experimentales de la cinética del secado y del modelo matemático para pulpa de cupuaçu (Theobroma grandiflorum en rodajas Kinetic drying experimental data and mathematical model for cupuaçu pulp (Theobroma grandiflora slices

    Directory of Open Access Journals (Sweden)

    Abraham Damian Giraldo-Zuniga

    2010-03-01

    Full Text Available En este trabajo fueron obtenidos experimentalmente la cinética del secado de la pulpa de cupuaçu en forma de rodajas con espesor de 0,5 cm. El secado fue realizado utilizándose un secador laboratorial de bandejas, a las temperaturas de 50, 60 y 70 ºC y a la velocidad del aire de secado de 1,5 m/s. De acuerdo con los datos de la cinética del secado se puede observar que cuanto mayor es la temperatura del secado mayor es la velocidad del secado. El tiempo requerido para secar el producto hasta una humedad del 20%, fueron 9,2, 8,1 y 7,3 horas para las temperaturas de secado de 50, 60 y 70 ºC respectivamente. Las curvas experimentales del secado fueron ajustados al modelo difusional de Fick considerándose la muestra como una lámina infinita y al modelo de Page. Los dos modelos se ajustaron bien a los datos experimentales. Los coeficientes de difusión del modelo de Fick variaron de 1.171 a 1.561 m/s².This work examined experimentally the kinetics of drying cupuaçu pulp (Theobroma grandiflorum slices. The experimental runs were driven in a laboratory dryer, at temperatures of 50, 60 and 70 ºC and an air drying velocity of 1.5 m/s. According to the kinetics study, increasing the temperature led to a decrease in drying time. The required drying times were 9.2, 8.1 and 7.3 hours for drying temperatures of 50, 60 and 70 ºC respectively. The experimental drying curves were adjusted to Fick's diffusional model for an infinite lamina with shrinkage and Page model. The diffusion coefficients of the Fick model varied between 1.171 and 1.561 m/s².

  3. Comparison of methods for extracting annual cycle with changing amplitude in climate science

    Science.gov (United States)

    Deng, Q.; Fu, Z.

    2017-12-01

    Changes of annual cycle gains a growing concern recently. The basic hypothesis regards annual cycle as constant. Climatology mean within a time period is usually used to depict the annual cycle. Obviously this hypothesis contradicts with the fact that annual cycle is changing every year. For the lack of a unified definition about annual cycle, the approaches adopted in extracting annual cycle are various and may lead to different results. The precision and validity of these methods need to be examined. In this work we numerical experiments with known monofrequent annual cycle are set to evaluate five popular extracting methods: fitting sinusoids, complex demodulation, Ensemble Empirical Mode Decomposition (EEMD), Nonlinear Mode Decomposition (NMD) and Seasonal trend decomposition procedure based on loess (STL). Three different types of changing amplitude will be generated: steady, linear increasing and nonlinearly varying. Comparing the annual cycle extracted by these methods with the generated annual cycle, we find that (1) NMD performs best in depicting annual cycle itself and its amplitude change, (2) fitting sinusoids, complex demodulation and EEMD methods are more sensitive to long-term memory(LTM) of generated time series thus lead to overfitting annual cycle and too noisy amplitude, oppositely the result of STL underestimate the amplitude variation (3)all of them can present the amplitude trend correctly in long-time scale but the errors on account of noise and LTM are common in some methods over short time scales.

  4. Evaluating the Aspect of Nuclear Material in Fuel Cycles

    Energy Technology Data Exchange (ETDEWEB)

    Takagi, Shunsuke; Pickett, Susan; Oda, Takuji; Choi, Jor-Shan; Kuno, Yusuke; Takana, Satoru [Department of Nuclear Engineering and Management, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8685 (Japan); Nagasaki, Shinya [Nuclear Professional School, The University of Tokyo (Japan)

    2009-06-15

    The increasing number of countries that wish to introduce nuclear power plants raises attention to proliferation resistance in nuclear power plants, and nuclear fuel cycle facilities. In order to achieve adequate proliferation resistance, it is important to evaluate it and to construct effective international institutional frameworks as well as technologies involving high level of proliferation resistance. Although some methods have been proposed for evaluation of the proliferation resistance, their validities have not been investigated in detail. In the present paper, therefore, we compare some of the proposed methodologies. It is essential to detect the abuse or diversion of nuclear material before the nuclear explosive device can be manufactured in order to prevent proliferation. The time needed for the detection of material primary depends on the safeguards that the country applies, and the time needed for fabrication mainly depends on the attributes of the nuclear material. Hence, we divided the proliferation resistance into two parts: the level of safeguards and the material. For examination of evaluation methods such as the one proposed by Charlton [1] or the figure of merit (FOM) [2], sensitivity analysis was performed on weighting factors and scenarios. The validity and characteristics of each method were discussed, focusing on the applicability of each method to the assessment of multi-national approaches such as GNEP. [1] W. S. Charlton, R. L. LeBouf, C. Gariazzo, D. G. Ford, C. Beard, S. Landeberger, M. Whitaker, 'Proliferation resistance assessment methodology for nuclear fuel cycles', Nuclear Technology, 157, 1 (2007). [2] C.G. Bathke et al, 'An assessment of the proliferation resistance of materials in advanced nuclear fuel cycles', 8. International Conference on Facility Operations (2008). (authors)

  5. Using neuro-fuzzy based method to develop nuclear turbine cycle model

    International Nuclear Information System (INIS)

    Chan Yeakuang; Chang Chinjang

    2009-01-01

    The purpose of this study is to describe a hybrid soft-computing modeling technique used to develop the steam turbine cycle model for nuclear power plants. The technique uses neuro-fuzzy model to predict the generator output. Firstly, the plant past three fuel cycles operating data above 95% load were collected and validated as the baseline performance data set. Then the signal errors for new operating data were detected by comparison with the baseline data set and their allowable range of variations. Finally, the most important parameters were selected as an input of the neuro-fuzzy based steam turbine cycle model. After training and testing with key parameters (i.e. throttle pressure, condenser backpressure, feedwater flow rate, and final feedwater temperature), the proposed model can be used to predict the generator output. The analysis results show this neuro-fuzzy based turbine cycle model can be used to predict the generator output with a good agreement. Moreover, the achievement of this study provides an alternative approach in thermal performance evaluation for nuclear power plants. (author)

  6. High pressure experimental water loop; Cellule experimentale a eau sous pression

    Energy Technology Data Exchange (ETDEWEB)

    Grenon, M [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires; Terny, M [Societe Grenobloise d' Etudes et d' Applications Hydrauliques, 38 (France)

    1958-07-01

    A high pressure experimental water loop has been made for studying the detection and evolution of cladding failure in a pressurized reactor. The loop has been designed for a maximum temperature of 360 deg. C, a maximum of 160 kg/cm{sup 2} and flow rates up to 5 m{sup 3}/h. The entire loop consists of several parts: a main circuit with a canned rotor circulation pump, steam pressurizer, heating tubes, two hydro-cyclones (one de-gasser and one decanter) and one tubular heat exchanger; a continuous purification loop, connected in parallel, comprising pressure reducing valves and resin pots which also allow studies of the stability of resins under pressure, temperature and radiation; following the gas separator is a gas loop for studying the recombination of the radiolytic gases in the steam phase. The preceding circuits, as well as others, return to a low pressure storage circuit. The cold water of the low pressure storage flask is continuously reintroduced into the high pressure main circuit by means of a return pump at a maximum head of 160 kg /cm{sup 2}, and adjusted to the pressurizer level. This loop is also a testing bench for the tight high pressure apparatus. The circulating pump and the connecting flanges (Oak Ridge type) are water-tight. The feed pump and the pressure reducing valves are not; the un-tight ones have a system of leak recovery. To permanently check the tightness the circuit has been fitted with a leak detection system (similar to the HRT one). (author)Fren. [French] Une cellule experimentale a eau sous pression a ete realisee pour l'etude de l'evolution et de la detection de ruptures de gaines dans le cas d'un reacteur pressurise. Les performances de ce circuit sont: 350 deg. C maximum pour la temperature et 160 kg/cm{sup 2} maximum pour la pression, le debit pouvant atteindre 5 m{sup 3}/h. Le circuit complet est constitue de plusieurs parties: un circuit principal avec pompe de circulation a rotor immerge, preiseur a vapeur, tubes chaudieres

  7. Systematic design of an intra-cycle fueling control system for advanced diesel combustion concepts

    NARCIS (Netherlands)

    Kefalidis, L.

    2017-01-01

    This technical report presents a systematic approach for the design and development of an intra-cycle fueling control system for diesel combustion concepts. A high level system was developed and implemented on an experimental engine setup. Implementation and experimental validation are performed for

  8. Optimum gas turbine cycle for combined cycle power plant

    International Nuclear Information System (INIS)

    Polyzakis, A.L.; Koroneos, C.; Xydis, G.

    2008-01-01

    The gas turbine based power plant is characterized by its relatively low capital cost compared with the steam power plant. It has environmental advantages and short construction lead time. However, conventional industrial engines have lower efficiencies, especially at part load. One of the technologies adopted nowadays for efficiency improvement is the 'combined cycle'. The combined cycle technology is now well established and offers superior efficiency to any of the competing gas turbine based systems that are likely to be available in the medium term for large scale power generation applications. This paper has as objective the optimization of a combined cycle power plant describing and comparing four different gas turbine cycles: simple cycle, intercooled cycle, reheated cycle and intercooled and reheated cycle. The proposed combined cycle plant would produce 300 MW of power (200 MW from the gas turbine and 100 MW from the steam turbine). The results showed that the reheated gas turbine is the most desirable overall, mainly because of its high turbine exhaust gas temperature and resulting high thermal efficiency of the bottoming steam cycle. The optimal gas turbine (GT) cycle will lead to a more efficient combined cycle power plant (CCPP), and this will result in great savings. The initial approach adopted is to investigate independently the four theoretically possible configurations of the gas plant. On the basis of combining these with a single pressure Rankine cycle, the optimum gas scheme is found. Once the gas turbine is selected, the next step is to investigate the impact of the steam cycle design and parameters on the overall performance of the plant, in order to choose the combined cycle offering the best fit with the objectives of the work as depicted above. Each alterative cycle was studied, aiming to find the best option from the standpoint of overall efficiency, installation and operational costs, maintainability and reliability for a combined power

  9. Combined Turbine and Cycle Optimization for Organic Rankine Cycle Power Systems—Part B: Application on a Case Study

    Directory of Open Access Journals (Sweden)

    Angelo La Seta

    2016-05-01

    Full Text Available Organic Rankine cycle (ORC power systems have recently emerged as promising solutions for waste heat recovery in low- and medium-size power plants. Their performance and economic feasibility strongly depend on the expander. The design process and efficiency estimation are particularly challenging due to the peculiar physical properties of the working fluid and the gas-dynamic phenomena occurring in the machine. Unlike steam Rankine and Brayton engines, organic Rankine cycle expanders combine small enthalpy drops with large expansion ratios. These features yield turbine designs with few highly-loaded stages in supersonic flow regimes. Part A of this two-part paper has presented the implementation and validation of the simulation tool TURAX, which provides the optimal preliminary design of single-stage axial-flow turbines. The authors have also presented a sensitivity analysis on the decision variables affecting the turbine design. Part B of this two-part paper presents the first application of a design method where the thermodynamic cycle optimization is combined with calculations of the maximum expander performance using the mean-line design tool described in part A. The high computational cost of the turbine optimization is tackled by building a model which gives the optimal preliminary design of an axial-flow turbine as a function of the cycle conditions. This allows for estimating the optimal expander performance for each operating condition of interest. The test case is the preliminary design of an organic Rankine cycle turbogenerator to increase the overall energy efficiency of an offshore platform. For an increase in expander pressure ratio from 10 to 35, the results indicate up to 10% point reduction in expander performance. This corresponds to a relative reduction in net power output of 8.3% compared to the case when the turbine efficiency is assumed to be 80%. This work also demonstrates that this approach can support the plant designer

  10. Systematic identification of yeast cell cycle transcription factors using multiple data sources

    Directory of Open Access Journals (Sweden)

    Li Wen-Hsiung

    2008-12-01

    Full Text Available Abstract Background Eukaryotic cell cycle is a complex process and is precisely regulated at many levels. Many genes specific to the cell cycle are regulated transcriptionally and are expressed just before they are needed. To understand the cell cycle process, it is important to identify the cell cycle transcription factors (TFs that regulate the expression of cell cycle-regulated genes. Results We developed a method to identify cell cycle TFs in yeast by integrating current ChIP-chip, mutant, transcription factor binding site (TFBS, and cell cycle gene expression data. We identified 17 cell cycle TFs, 12 of which are known cell cycle TFs, while the remaining five (Ash1, Rlm1, Ste12, Stp1, Tec1 are putative novel cell cycle TFs. For each cell cycle TF, we assigned specific cell cycle phases in which the TF functions and identified the time lag for the TF to exert regulatory effects on its target genes. We also identified 178 novel cell cycle-regulated genes, among which 59 have unknown functions, but they may now be annotated as cell cycle-regulated genes. Most of our predictions are supported by previous experimental or computational studies. Furthermore, a high confidence TF-gene regulatory matrix is derived as a byproduct of our method. Each TF-gene regulatory relationship in this matrix is supported by at least three data sources: gene expression, TFBS, and ChIP-chip or/and mutant data. We show that our method performs better than four existing methods for identifying yeast cell cycle TFs. Finally, an application of our method to different cell cycle gene expression datasets suggests that our method is robust. Conclusion Our method is effective for identifying yeast cell cycle TFs and cell cycle-regulated genes. Many of our predictions are validated by the literature. Our study shows that integrating multiple data sources is a powerful approach to studying complex biological systems.

  11. Development and validation of models for simulation of supercritical carbon dioxide Brayton cycles and application to self-propelling heat removal systems in boiling water reactors

    International Nuclear Information System (INIS)

    Venker, Jeanne

    2015-01-01

    The objective of the current work was to develop a model that is able to describe the transient behavior of supercritical carbon dioxide (sCO 2 ) Brayton cycles, to be applied to self-propelling residual heat removal systems in boiling water reactors. The developed model has been implemented into the thermohydraulic system code ATHLET. By means of this improved ATHLET version, novel residual heat removal systems, which are based on closed sCO 2 Brayton cycles, can be assessed as a retrofit measure for present light water reactors. Transient simulations are hereby of great importance. The heat removal system has to be modeled explicitly to account for the interaction between the system and the behavior of the plant during different accident conditions. As a first step, transport and thermodynamic fluid properties of supercritical carbon dioxide have been implemented in ATHLET to allow for the simulation of the new working fluid. Additionally, a heat transfer correlation has been selected to represent the specific heat transfer of supercritical carbon dioxide. For the calculation of pressure losses due to wall friction, an approach for turbulent single phase flow has been adopted that is already implemented in ATHLET. In a second step, a component model for radial compressors has been implemented in the system code. Furthermore, the available model for axial turbines has been adapted to simulate the transient behavior of radial turbines. All extensions have been validated against experimental data. In order to simulate the interaction between the self-propelling heat removal system and a generic boiling water reactor, the components of the sCO 2 Brayton cycle have been dimensioned with first principles. An available input deck of a generic BWR has then been extended by the residual heat removal system. The modeled application has shown that the extended version of ATHLET is suitable to simulate sCO 2 Brayton cycles and to evaluate the introduced heat removal system

  12. Temporal controls of the asymmetric cell division cycle in Caulobacter crescentus.

    Directory of Open Access Journals (Sweden)

    Shenghua Li

    2009-08-01

    Full Text Available The asymmetric cell division cycle of Caulobacter crescentus is orchestrated by an elaborate gene-protein regulatory network, centered on three major control proteins, DnaA, GcrA and CtrA. The regulatory network is cast into a quantitative computational model to investigate in a systematic fashion how these three proteins control the relevant genetic, biochemical and physiological properties of proliferating bacteria. Different controls for both swarmer and stalked cell cycles are represented in the mathematical scheme. The model is validated against observed phenotypes of wild-type cells and relevant mutants, and it predicts the phenotypes of novel mutants and of known mutants under novel experimental conditions. Because the cell cycle control proteins of Caulobacter are conserved across many species of alpha-proteobacteria, the model we are proposing here may be applicable to other genera of importance to agriculture and medicine (e.g., Rhizobium, Brucella.

  13. Temporal controls of the asymmetric cell division cycle in Caulobacter crescentus.

    Science.gov (United States)

    Li, Shenghua; Brazhnik, Paul; Sobral, Bruno; Tyson, John J

    2009-08-01

    The asymmetric cell division cycle of Caulobacter crescentus is orchestrated by an elaborate gene-protein regulatory network, centered on three major control proteins, DnaA, GcrA and CtrA. The regulatory network is cast into a quantitative computational model to investigate in a systematic fashion how these three proteins control the relevant genetic, biochemical and physiological properties of proliferating bacteria. Different controls for both swarmer and stalked cell cycles are represented in the mathematical scheme. The model is validated against observed phenotypes of wild-type cells and relevant mutants, and it predicts the phenotypes of novel mutants and of known mutants under novel experimental conditions. Because the cell cycle control proteins of Caulobacter are conserved across many species of alpha-proteobacteria, the model we are proposing here may be applicable to other genera of importance to agriculture and medicine (e.g., Rhizobium, Brucella).

  14. MODEL LEARNING CYCLE 5E DENGAN PENDEKATAN SCIENTIFIC UNTUK MENINGKATKAN DISPOSISI MATEMATIS DAN BERPIKIR KRITIS

    Directory of Open Access Journals (Sweden)

    Sofuroh -

    2014-02-01

    Full Text Available AbstrakTujuan penelitian ini adalah untuk menghasilkan perangkat pembelajaran matema-tika yang valid, praktis dan pembelajaran yang efektif. Model pengembangan pemb-elajaran mengacu pada model Plomp. Hasil pengembangan perangkat pembelajaransebagaiberikut: (1perangkat pembelajaranyangdikembangkan valid;silabusadalah4,32 (sangatbaik; RPPadalah 4,42 (sangatbaik; LKSadalah4,28 (sangatbaik;bukusiswaadalah 4,32 (sangatbaik; danTKBKadalah4,40 (sangatbaik;(2perangkat pembelajaran dinyatakanpraktis,yaitu:akemampuangurumengelolakelas rata-ratanya4,10 (baik;danbresponsiswapositif denganrata-rata85,5%; (3 pembelajaran matematika dinyatakan efektif  yaitu: a KBK siswa secaraindividu minimal mencapai kriteria 75, serta  proporsi siswa mendapatkan nilaiminimal KBKsama dengan 75 melebihi 75%; b adanya pengaruh positif  disposisimatematis dan keterampilan berpikir kritis terhadap KBKsebesar 95,5%; c berdasarkanuji banding KBK kelas LearningCycle5E dengan pendekatan Scientificlebihbaikdari pada kelas ekspositori;dan d adanyapeningkatan disposisimatematissebesar0,47,keterampilanberpikirkritissebesar0,35dankemampuan berpikirkritissebesar 0,47. Hasilpenelitianperangkat pembelajaran dengan LearningCycle5Edengan pendekatan Scientifictelah valid dan terbukti praktis dan efektif.AbstractThe purpose of  this study was to produce a valid mathematics learning equipment, practical,and to determine the effectiveness of  learning. The research that used is instructional developmentmodelwhichrefersto a Plomp’smodel. Theresultof learning equipment development asfollows: (1 learning equipment developed is valid: syllabus 4,32 (very good; RPP4,42 (verygood; LKS4, 28(very good; student books 4,32(very good; and TKBK 4,40 (very good;(2 learning tool use specified practice: a ability to manage classroom teacheris an average4,10 (verygood, b the positive student response to learning has an average 85,5%;(3 learningmathematicseffective:a the proportionof students who learn

  15. Exhaust gas recirculation for advanced diesel combustion cycles

    International Nuclear Information System (INIS)

    Asad, Usman; Zheng, Ming

    2014-01-01

    Highlights: • Analysis of the incremental (cycle-by-cycle) build-up of EGR. • Proposed one-step equations for transient/steady-state gas concentration estimation. • Defined an in-cylinder excess-air ratio to account for the recycled oxygen with EGR. • Demonstrated the use of intake oxygen as a reliable measure of EGR effectiveness. • Demonstrated the impact of engine load and intake pressure on EGR effectiveness. - Abstract: Modern diesel engines tend to utilize significantly large quantities of exhaust gas recirculation (EGR) and high intake pressures across the engine load range to meet NOx targets. At such high EGR rates, the combustion process and exhaust emissions tend to exhibit a marked sensitivity to small changes in the EGR quantity, resulting in unintended deviations from the desired engine performance characteristics (energy efficiency, emissions, stability). An accurate estimation of EGR and its effect on the intake dilution are, therefore, necessary to enable its application during transient engine operation or unstable combustion regimes. In this research, a detailed analysis that includes estimation of the transient (cycle-by-cycle) build-up of EGR and the time (engine cycles) required to reach the steady-state EGR operation has been carried out. One-step global equations to calculate the transient and steady-state gas concentrations in the intake and exhaust are proposed. The effects of engine load and intake pressure on EGR have been examined and explained in terms of intake charge dilution and in-cylinder excess-air ratio. The EGR analysis is validated against a wide range of empirical data that include low temperature combustion cycles, intake pressure and load sweeps. This research intends to not only formulate a clear understanding of EGR application for advanced diesel combustion but also to set forth guidelines for transient analysis of EGR

  16. Validation of the AmpFlSTR« SEfiler Plus(TM) PCR Amplification kit for forensic STR analysis

    DEFF Research Database (Denmark)

    Fredslund, Stine Frisk; Mogensen, Helle Smidt; Morling, Niels

    2009-01-01

    Validation of the AmpFlSTR« SEfiler Plus(TM) PCR Amplification kit with 29 and 30 PCR cycles for forensic STR analysis demonstrated that the kit had fewer artefacts than the AmpFlSTR« SGM Plus(TM) kit (28 PCR cycles). The SEfiler Plus kit was more sensitive and devoid of colour artefacts, but sho......, but showed more stutters, drop-ins, drop-outs and allelic imbalances...

  17. MODELING AND EXPERIMENTAL VALIDATION TO ESTIMATE THE ENERGY BALANCE FOR A POULTRY HOUSE WITH MISTING COOLING

    OpenAIRE

    JAIRO ALEXANDER OSORIO SARAZ; ILDA DE FÁTIMA FERREIRA TINÔCO; KELLER SULLIVAN OLIVEIRA ROCHA; MARCIO ARÊDES MARTINS; MARCOS OLIVEIRA DE PAULA

    2011-01-01

    Este trabajo tuvo como objetivo desarrollar y validar un modelo matemático simplificado en estado permanente, para predecir la distribución de temperatura en un galpón avícola comercial, equipado con sistemas de ventilación de presión negativa y nebulización interna. El modelo fue validado a partir de datos experimentales obtenidos en condiciones de verano. Se encontró para condiciones con temperatura externas de 26, 27, e 29°C, las mejores combinaciones que debe tener el galpón, entre la...

  18. Cycles and Common Cycles in Property and Related Sectors

    OpenAIRE

    Peijie Wang

    2003-01-01

    This paper examines cycles and common cycles in the property market and the economy. While focusing on common cycles, the study also incorporates common trends in the meantime, so it covers the whole spectrum of dynamic analysis. It has been found that property shares common cycles, particularly with those sectors that are the user markets of property. The mechanisms of common cycles and the relative magnitudes of cycles of the sectors related to property are discussed to shed light on proper...

  19. On period doubling bifurcations of cycles and the harmonic balance method

    International Nuclear Information System (INIS)

    Itovich, Griselda R.; Moiola, Jorge L.

    2006-01-01

    This works attempts to give quasi-analytical expressions for subharmonic solutions appearing in the vicinity of a Hopf bifurcation. Starting with well-known tools as the graphical Hopf method for recovering the periodic branch emerging from classical Hopf bifurcation, precise frequency and amplitude estimations of the limit cycle can be obtained. These results allow to attain approximations for period doubling orbits by means of harmonic balance techniques, whose accuracy is established by comparison of Floquet multipliers with continuation software packages. Setting up a few coefficients, the proposed methodology yields to approximate solutions that result from a second period doubling bifurcation of cycles and to extend the validity limits of the graphical Hopf method

  20. Predicting the success of IVF: external validation of the van Loendersloot's model.

    Science.gov (United States)

    Sarais, Veronica; Reschini, Marco; Busnelli, Andrea; Biancardi, Rossella; Paffoni, Alessio; Somigliana, Edgardo

    2016-06-01

    Is the predictive model for IVF success proposed by van Loendersloot et al. valid in a different geographical and cultural context? The model discriminates well but was less accurate than in the original context where it was developed. Several independent groups have developed models that combine different variables with the aim of estimating the chance of pregnancy with IVF but only four of them have been externally validated. One of these four, the van Loendersloot's model, deserves particular attention and further investigation for at least three reasons; (i) the reported area under the receiver operating characteristics curve (c-statistics) in the temporal validation setting was the highest reported to date (0.68), (ii) the perspective of the model is clinically wise since it includes variables obtained from previous failed cycles, if any, so it can be applied to any women entering an IVF cycle, (iii) the model lacks external validation in a geographically different center. Retrospective cohort study of women undergoing oocyte retrieval for IVF between January 2013 and December 2013 at the infertility unit of the Fondazione Ca' Granda, Ospedale Maggiore Policlinico of Milan, Italy. Only the first oocyte retrieval cycle performed during the study period was included in the study. Women with previous IVF cycles were excluded if the last one before the study cycle was in another center. The main outcome was the cumulative live birth rate per oocytes retrieval. Seven hundred seventy-two women were selected. Variables included in the van Loendersloot's model and the relative weights (beta) were used. The variable resulting from this combination (Y) was transformed into a probability. The discriminatory capacity was assessed using the c-statistics. Calibration was made using a logistic regression that included Y as the unique variable and live birth as the outcome. Data are presented using both the original and the calibrated models. Performance was evaluated

  1. Experimental and numerical study of two-phase flows at the inlet of evaporators in vapour compression cycles; Etude experimentale et numerique d'ecoulements diphasiques a l'entree des evaporateurs de cycles thermodynamiques

    Energy Technology Data Exchange (ETDEWEB)

    Ahmad, M

    2007-09-15

    Maldistribution of liquid-vapour two phase flows causes a significant decrease of the thermal and hydraulic performance of evaporators in thermodynamic vapour compression cycles. A first experimental installation was used to visualize the two phase flow evolution between the expansion valve and the evaporator inlet. A second experimental set-up simulating a compact heat exchanger has been designed to identify the functional and geometrical parameters creating the best distribution of the two phases in the different channels. An analysis and a comprehension of the relation between the geometrical and functional parameters with the flow pattern inside the header and the two phase distribution, has been established. A numerical simulations of a stratified flow and a stratified jet flow have been carried out using two CFD codes: FLUENT and NEPTUNE. In the case of a fragmented jet configuration, a global definition of the interfacial area concentration for a separated phases and dispersed phases flow has been established and a model calculating the fragmented mass fraction has been developed. (author)

  2. Scale-4 analysis of pressurized water reactor critical configurations: Volume 5, North Anna Unit 1 Cycle 5

    International Nuclear Information System (INIS)

    Bowman, S.M.; Suto, T.

    1996-10-01

    ANSI/ANS 8.1 requires that calculational methods for away-from- reactor (AFR) criticality safety analyses be validated against experiment. This report summarizes part of the ongoing effort to benchmark AFR criticality analysis methods using selected critical configurations from commercial PWRs. Codes and data in the SCALE-4 code system were used. This volume documents the SCALE system analysis of one reactor critical configuration for North Anna Unit 1 Cycle 5. The KENO V.a criticality calculations for the North Anna 1 Cycle 5 beginning-of-cycle model yielded a value for k eff of 1. 0040±0.0005

  3. HCl removal using cycled carbide slag from calcium looping cycles

    International Nuclear Information System (INIS)

    Xie, Xin; Li, Yingjie; Wang, Wenjing; Shi, Lei

    2014-01-01

    Highlights: • Cycled carbide slag from calcium looping cycles is used to remove HCl. • The optimum temperature for HCl removal of cycled carbide slag is 700 °C. • The presence of CO 2 restrains HCl removal of cycled carbide slag. • CO 2 capture conditions have important effects on HCl removal of cycled carbide slag. • HCl removal capacity of carbide slag drops with cycle number rising from 1 to 50. - Abstract: The carbide slag is an industrial waste from chlor-alkali plants, which can be used to capture CO 2 in the calcium looping cycles, i.e. carbonation/calcination cycles. In this work, the cycled carbide slag from the calcium looping cycles for CO 2 capture was proposed to remove HCl in the flue gas from the biomass-fired and RDFs-fired boilers. The effects of chlorination temperature, HCl concentration, particle size, presence of CO 2 , presence of O 2 , cycle number and CO 2 capture conditions in calcium looping cycles on the HCl removal behavior of the carbide slag experienced carbonation/calcination cycles were investigated in a triple fixed-bed reactor. The chlorination product of the cycled carbide slag from the calcium looping after absorbing HCl is not CaCl 2 but CaClOH. The optimum temperature for HCl removal of the cycled carbide slag from the carbonation/calcination cycles is 700 °C. The chlorination conversion of the cycled carbide slag increases with increasing the HCl concentration. The cycled carbide slag with larger particle size exhibits a lower chlorination conversion. The presence of CO 2 decreases the chlorination conversions of the cycled carbide slag and the presence of O 2 has a trifling impact. The chlorination conversion of the carbide slag experienced 1 carbonation/calcination cycle is higher than that of the uncycled calcined sorbent. As the number of carbonation/calcination cycles increases from 1 to 50, the chlorination conversion of carbide slag drops gradually. The high calcination temperature and high CO 2

  4. Experimental validation of calculated capture rate for nucleus involved in fuel cycle

    International Nuclear Information System (INIS)

    Benslimane-Bouland, A.

    1997-09-01

    The framework of this study was the evaluation of the nuclear data requirements for Actinides and Fission Products applied to current nuclear reactors as well as future applications. This last item includes extended irradiation campaigns, 100 % Mixed Oxide fuel, transmutation or even incineration. The first part of this study presents different types of integral measurements which are available for capture rate measurements, as well as the methods used for reactor core calculation route design and nuclear data library validation. The second section concerns the analysis of three specific irradiation experiments. The results have shown the extent of the current knowledge on nuclear data as well as the associated uncertainties. The third and last section shows both the coherency between all the results, and the statistical method applied for nuclear data library adjustment. A relevant application of this method has demonstrated that only specifically chosen integral experiments can be of use for the validation of nuclear data libraries. The conclusion is reached that even if co-ordinated efforts between reactor and nuclear physicists have made possible a huge improvement in the knowledge of capture cross sections of the main nuclei such as uranium and plutonium, some improvements are currently necessary for the minor actinides (Np, Am and Cm). Both integral and differential measurements are recommended to improve the knowledge of minor actinide cross sections. As far as integral experiments are concerned, a set of criteria to be followed during the experimental conception have been defined in order to both reduce the number of required calculation approximations, and to increase as much as possible the maximum amount of extracted information. (author)

  5. Systems Analyses of Advanced Brayton Cycles

    Energy Technology Data Exchange (ETDEWEB)

    A.D. Rao; D.J. Francuz; J.D. Maclay; J. Brouwer; A. Verma; M. Li; G.S. Samuelsen

    2008-09-30

    The main objective is to identify and assess advanced improvements to the Brayton Cycle (such as but not limited to firing temperature, pressure ratio, combustion techniques, intercooling, fuel or combustion air augmentation, enhanced blade cooling schemes) that will lead to significant performance improvements in coal based power systems. This assessment is conducted in the context of conceptual design studies (systems studies) that advance state-of-art Brayton cycles and result in coal based efficiencies equivalent to 65% + on natural gas basis (LHV), or approximately an 8% reduction in heat rate of an IGCC plant utilizing the H class steam cooled gas turbine. H class gas turbines are commercially offered by General Electric and Mitsubishi for natural gas based combined cycle applications with 60% efficiency (LHV) and it is expected that such machine will be offered for syngas applications within the next 10 years. The studies are being sufficiently detailed so that third parties will be able to validate portions or all of the studies. The designs and system studies are based on plants for near zero emissions (including CO{sub 2}). Also included in this program is the performance evaluation of other advanced technologies such as advanced compression concepts and the fuel cell based combined cycle. The objective of the fuel cell based combined cycle task is to identify the desired performance characteristics and design basis for a gas turbine that will be integrated with an SOFC in Integrated Gasification Fuel Cell (IGFC) applications. The goal is the conceptualization of near zero emission (including CO{sub 2} capture) integrated gasification power plants producing electricity as the principle product. The capability of such plants to coproduce H{sub 2} is qualitatively addressed. Since a total systems solution is critical to establishing a plant configuration worthy of a comprehensive market interest, a baseline IGCC plant scheme is developed and used to study

  6. The development of learning material using learning cycle 5E model based stem to improve students’ learning outcomes in Thermochemistry

    Science.gov (United States)

    sugiarti, A. C.; suyatno, S.; Sanjaya, I. G. M.

    2018-04-01

    The objective of this study is describing the feasibility of Learning Cycle 5E STEM (Science, Technology, Engineering, and Mathematics) based learning material which is appropriate to improve students’ learning achievement in Thermochemistry. The study design used 4-D models and one group pretest-posttest design to obtain the information about the improvement of sudents’ learning outcomes. The subject was learning cycle 5E based STEM learning materials which the data were collected from 30 students of Science class at 11th Grade. The techniques used in this study were validation, observation, test, and questionnaire. Some result attain: (1) all the learning materials contents were valid, (2) the practicality and the effectiveness of all the learning materials contents were classified as good. The conclution of this study based on those three condition, the Learnig Cycle 5E based STEM learning materials is appropriate to improve students’ learning outcomes in studying Thermochemistry.

  7. Validation of CATHARE for gas-cooled reactors

    International Nuclear Information System (INIS)

    Fabrice Bentivoglio; Ola Widlund; Manuel Saez

    2005-01-01

    Full text of publication follows: Extensively validated and qualified for light-water reactor safety studies, the thermo-hydraulics code CATHARE has been adapted to deal also with gas-cooled reactor applications. In order to validate the code for these novel applications, CEA (Commissariat a l'Energie Atomique) has initiated an ambitious long-term experimental program. The foreseen experimental facilities range from small-scale loops for physical correlations, to component technology and system demonstration loops. In the short-term perspective, CATHARE is being validated against existing experimental data, in particular from the German power plant Oberhausen II and the South African Pebble-Bed Micro Model (PBMM). Oberhausen II, operated by the German utility EVO, is a 50 MW(e) direct-cycle Helium turbine plant. The power source is a gas burner rather than a nuclear reactor core, but the power conversion system resembles those of the GFR (Gas-cooled Fast Reactor) and other high-temperature reactor concepts. Oberhausen II was operated for more than 100 000 hours between 1974 and 1988. Design specifications, drawings and experimental data have been obtained through the European HTR project, offering a unique opportunity to validate CATHARE on a large-scale Brayton cycle. Available measurements of temperatures, pressures and mass flows throughout the circuit have allowed a very comprehensive thermohydraulic description of the plant, in steady-state conditions as well as during transients. The Pebble-Bed Micro Model (PBMM) is a small-scale model conceived to demonstrate the operability and control strategies of the South African PBMR concept. The model uses Nitrogen instead of Helium, and an electrical heater with a maximum rating of 420 kW. As the full-scale PBMR, the PBMM loop features three turbines and two compressors on the primary circuit, located on three separate shafts. The generator, however, is modelled by a third compressor on a separate circuit, with a

  8. The database 'EDUD Base' for validation of neutron-physics codes used to analyze the WWER-440 cores

    International Nuclear Information System (INIS)

    Rocek, J.; Belac, J.; Miasnikov, A.

    2003-01-01

    The program and data system EDUDBase for validation of reactor computing codes was developed at NRI. It is designed for validation and evaluation of the precision of different computer codes used for WWER core analyses. The main goal of this database is to provide data for comparison with calculation results of tested codes and tools for statistical analysis or differences between the calculation results and the test data. The benchmark data sets are based on in-core measurements performed on WWER-440 reactors of Dukovany NPP. The initial data from NPP are verified, errors and inaccuracies are eliminated and data are transferred to a form, which is suitable for comparison with results of calculations. A special reduced operating history data set is created for each operating cycle ('Benchmark Operation History') to be used as an input data for calculation. It contains values of some integral quantities for each time point: effective time, integral thermal power, boron concentration, position of working group control assemblies (group 6) and inlet coolant temperature. At present, sets are available for all completed cycles up to: (unit/cycle) 1/17, 2/16, 3/15, 4/15. Power distribution is described for approx. 40 time steps during each operating cycle. 2D-power distributions are transferred into 60-degree core symmetry sector of reactor core. At present, such data sets are available only for later cycles starting with: (unit/cycle) 1/7, 2/6, 3/5, 4/5 (in other words last II cycles for each unit) (Authors)

  9. RESEM-CA: Validation and testing

    Energy Technology Data Exchange (ETDEWEB)

    Pal, Vineeta; Carroll, William L.; Bourassa, Norman

    2002-09-01

    This report documents the results of an extended comparison of RESEM-CA energy and economic performance predictions with the recognized benchmark tool DOE2.1E to determine the validity and effectiveness of this tool for retrofit design and analysis. The analysis was a two part comparison of patterns of (1) monthly and annual energy consumption of a simple base-case building and controlled variations in it to explore the predictions of load components of each program, and (2) a simplified life-cycle cost analysis of the predicted effects of selected Energy Conservation Measures (ECMs). The study tries to analyze and/or explain the differences that were observed. On the whole, this validation study indicates that RESEM is a promising tool for retrofit analysis. As a result of this study some factors (incident solar radiation, outside air film coefficient, IR radiation) have been identified where there is a possibility of algorithmic improvements. These would have to be made in a way that does not sacrifice the speed of the tool, necessary for extensive parametric search of optimum ECM measures.

  10. Real-Time Gait Cycle Parameter Recognition Using a Wearable Accelerometry System

    Directory of Open Access Journals (Sweden)

    Jun-Ming Lu

    2011-07-01

    Full Text Available This paper presents the development of a wearable accelerometry system for real-time gait cycle parameter recognition. Using a tri-axial accelerometer, the wearable motion detector is a single waist-mounted device to measure trunk accelerations during walking. Several gait cycle parameters, including cadence, step regularity, stride regularity and step symmetry can be estimated in real-time by using autocorrelation procedure. For validation purposes, five Parkinson’s disease (PD patients and five young healthy adults were recruited in an experiment. The gait cycle parameters among the two subject groups of different mobility can be quantified and distinguished by the system. Practical considerations and limitations for implementing the autocorrelation procedure in such a real-time system are also discussed. This study can be extended to the future attempts in real-time detection of disabling gaits, such as festinating or freezing of gait in PD patients. Ambulatory rehabilitation, gait assessment and personal telecare for people with gait disorders are also possible applications.

  11. Discharge data from 50 selected rivers for GCM validation

    International Nuclear Information System (INIS)

    Duemenil, L.; Isele, K.; Liebscher, H.J.; Schroeder, U.; Schumacher, M.; Wilke, K.

    1993-01-01

    This Technical Report refers to a joint project between GRDC Koblenz and MPI Hamburg. The Global Runoff Data Centre operates under the auspieces of WMO at the Federal Institute of Hydrology (Bundesanstalt fuer Gewaesserkunde) in Koblenz. River discharge data of the 50 largest rivers provide an independent data source for the validation of the hydrological cycle in general circulation models. This type of data is particularly valuable, because in some cases the available time series are exceptionally long. The data are presented as time series of annual average discharge (averaged over the period for which data is available, see below for caveats) and as annual cycles of monthly mean discharge averaged over the length of the time series available. (orig./KW)

  12. Validation of a zero-dimensional and 2-phase combustion model for dual-fuel compression ignition engine simulation

    Directory of Open Access Journals (Sweden)

    Mikulski Maciej

    2017-01-01

    Full Text Available Increasing demands for the reduction of exhaust emissions and the pursuit to re-duce the use of fossil fuels require the search for new fuelling technologies in combustion engines. One of the most promising technologies is the multi-fuel compression ignition engine concept, in which a small dose of liquid fuel injected directly into the cylinder acts as the ignition inhibitor of the gaseous fuel. Achieving the optimum combustion process in such an engine requires the application of advanced control algorithms which require mathematical modelling support. In response to the growing demand for new simulation tools, a 0-D model of a dual-fuel engine was proposed and validated. The validation was performed in a broad range of engine operating points, including various speeds and load condition, as well as different natural gas/diesel blend ratios. It was demonstrated that the average model calculation error within the entire cycle did not exceed 6.2%, and was comparable to the measurement results cycle to cycle variations. The maximum model calculation error in a single point of a cycle was 15% for one of the complex (multipoint injection cases. In other cases, it did not exceed 11%.

  13. Criticality safety research on nuclear fuel cycle facility

    Energy Technology Data Exchange (ETDEWEB)

    Miyoshi, Yoshinori [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    2004-07-01

    This paper present d s current status and future program of the criticality safety research on nuclear fuel cycle made by Japan Atomic Energy Research Institute. Experimental research on solution fuel treated in reprocessing plant has been performed using two critical facilities, STACY and TRACY. Fundamental data of static and transient characteristics are accumulated for validation of criticality safety codes. Subcritical measurements are also made for developing a monitoring system for criticality safety. Criticality safety codes system for solution and power system, and evaluation method related to burnup credit are developed. (author)

  14. Efficient cycle jumping techniques for the modelling of materials and structures under cyclic mechanical and thermal loading

    International Nuclear Information System (INIS)

    Dunne, F.P.E.; Hayhurst, D.R.

    1994-01-01

    Highly efficient cycle jumping algorithms have been developed for the calculation of stress and damage histories for both cyclic mechanical and cycle thermal loading. The techniques have been shown to be suitable for cyclic plasticity; creep-cyclic plasticity interaction; and creep dominated material behaviour. The cycle jumping algorithms have been validated by comparison of the predictions made using both the cycle jumping technique, and the full calculation involving the integration of the equations around all cycles. Excellent agreement has been achieved, and significant reductions in computer processing time of up to 90% have been obtained by using the cycle jumping technique. A further cycle jumping technique has been developed for full component analysis, using a viscoplastic damage finite element solver, which enables stress redistribution to be modelled. The behaviour and lifetime of a slag tap component has been predicted when subjected to cyclic thermal loading. Cyclic plasticity damage and micro-crack initiation is predicted to occur at the water cooling duct after 2.974 cycles, with damage and micro-crack evolution arresting after 60.000. (author). 18 refs., 13 figs., 4 photos

  15. Assessment of watershed scale nitrogen cycling and dynamics by hydrochemical modeling

    Science.gov (United States)

    Onishi, T.; Hiramatsu, K.; Somura, H.

    2017-12-01

    Nitrogen cycling in terrestrial areas is affecting water quality and ecosystem of aquatic area such as lakes and oceans through rivers. Owing to the intensive researches on nitrogen cycling in each different type of ecosystem, we acquired rich knowledge on nitrogen cycling of each ecosystem. On the other hand, since watershed are composed of many different kinds of ecosystems, nitrogen cycling in a watershed as a complex of these ecosystems is not well quantified. Thus, comprehensive understanding of nitrogen cycling of watersheds by modelling efforts are required. In this study, we attempted to construct hydrochemical model of the Ise Bay watershed to reproduce discharge, TN, and NO3 concentration. The model is based on SWAT (Soil and Water Assessment Tools) model. As anthropogenic impacts related to both hydrological cycling and nitrogen cycling, agricultural water intake/drainage, and domestic water intake/drainage were considered. In addition, fertilizer input to agricultural lands were also considered. Calibration period and validation period are 2004-2006, and 2007-2009, respectively. As a result of calibration using 2000 times LCS (Latin Cubic Sampling) method, discharge of rivers were reproduced fairly well with NS of 0.6-0.8. In contrast, the calibration result of TN and NO3 concentration tended to show overestimate values in spite of considering parameter uncertainties. This implies that unimplemented denitrification processes in the model. Through exploring the results, it is indicated that riparian areas, and agricultural drainages might be important spots for denitrification. Based on the result, we also attempted to evaluate the impact of climate change on nitrogen cycling. Though it is fully explored, this result will also be reported.

  16. Cycle life performance of rechargeable lithium ion batteries and mathematical modeling

    Science.gov (United States)

    Ning, Gang

    Capacity fade of commercial Sony US 18650 Li-ion batteries cycled at high discharge rates was studied at ambient temperature. Battery cycled at the highest discharge rate (3 C) shows the largest internal resistance increase of 27.7% relative to the resistance of fresh battery. It's been observed anode carbon loses 10.6% of its capability to intercalate or deintercalate Li+ after it was subjected to 300 cycles at discharge rate of 3 C. This loss dominates capacity fade of full battery. A mechanism considering continuous parasitic reaction at anode/electrolyte interface and film thickening has been proposed. First principles based charge-discharge models to simulate cycle life behavior of rechargeable Li-ion batteries have been developed. In the generalized model, transport in both electrolyte phase and solid phase were simultaneously taken into account. Under mild charge-discharge condition, transport of lithium in the electrolyte phase has been neglected in the simplified model. Both models are based on loss of the active lithium ions due to the electrochemical parasitic reaction at anode/electrolyte interface and on rise of the anode film resistance. The effect of parameters such as depth of discharge (DOD), end of charge voltage (EOCV) and overvoltage of the parasitic reaction on the cycle life behavior of a battery has been analyzed. The experimental results obtained at a charge rate of 1 C, discharge rate of 0.5 C, EOCV of 4.0 V and DOD of 0.4 have been used to validate cycle life models. Good agreement between the simulations and the experiments has been achieved up to 1968 cycles with both models. Simulation of cycle life of battery under multiple cycling regimes has also been demonstrated.

  17. A model for high-cycle fatigue crack propagation

    Energy Technology Data Exchange (ETDEWEB)

    Balbi, Marcela Angela [Rosario National Univ. (Argentina); National Council of Scientific Research and Technology (CONICET) (Argentina)

    2017-02-01

    This paper deals with the prediction of high-cycle fatigue behavior for four different materials (7075-T6 alloy, Ti-6Al-4 V alloy, JIS S10C steel and 0.4 wt.-% C steel) using Chapetti's approach to estimate the fatigue crack propagation curve. In the first part of the paper, a single integral equation for studying the entire propagation process is determined using the recent results of Santus and Taylor, which consider a double regime of propagation (short and long cracks) characterized by the model of El Haddad. The second part of the paper includes a comparison of the crack propagation behavior model proposed by Navarro and de los Rios with the one mentioned in the first half of this work. The results allow us to conclude that the approach presented in this paper is a good and valid estimation of high-cycle fatigue crack propagation using a single equation to describe the entire fatigue crack regime.

  18. Modeling and analysis of a transcritical rankine power cycle with a low grade heat source

    DEFF Research Database (Denmark)

    Nguyen, Chan; Veje, Christian

    efficiency, exergetic efficiency and specific net power output. A generic cycle configuration has been used for analysis of a geothermal energy heat source. This model has been validated against similar calculations using industrial waste heat as the energy source. Calculations are done with fixed...

  19. Effect of KOH concentration on LEO cycle life of IPV nickel-hydrogen flight cell - Update II

    Science.gov (United States)

    Smithrick, John J.; Hall, Stephen W.

    1992-01-01

    An update of validation test results confirming the breakthrough in LEO cycle life of nickel-hydrogen cells containing 26 percent KOH electrolyte is presented. A breakthrough in the LEO cycle life of individual pressure vessel (IPV) nickel-hydrogen cells has been previously reported. The cycle life of boiler plate cells containing 26 percent potassium hydroxide (KOH) electrolyte was about 40,000 LEO cycles, compared to 3500 cycles for cells containing 31 percent KOH. The cycle regime was a stressful accelerated LEO, which consisted of a 27.5 min charge followed by a 17.5 min discharge (2X normal rate). The depth-of-discharge was 80 percent. Six 48-Ah Hughes recirculation design IPV nickel-hydrogen flight battery cells are being evaluated. Three of the cells contain 26 percent KOH (test cells), and three contain 31 percent KOH (control cells). They are undergoing real time LEO cycle life testing. The cycle regime is a 90-min LEO orbit consisting of a 54-min charge followed by a 36-min discharge. The depth-of-discharge is 80 percent. The cell temperature is maintained at 10 C. The three 31 percent KOH cells failed (cycles 3729, 4165, and 11355). One of the 26 percent KOH cells failed at cycle 15314. The other two 26 percent KOH cells were cycled for over 16,000 cycles during the continuing test.

  20. Cross check of the new economic and mass balance feature of the fuel cycle scenario code TR-EVOL

    International Nuclear Information System (INIS)

    Merino-Rodriguez, I.; Garcia-Martinez, M.; Alvarez-Velarde, F.; Lopez, D.

    2016-01-01

    Versatile computational tools with up to date capabilities are needed to assess current nuclear fuel cycles or the transition from the current status of the fuel cycle to the more advanced and sustainable ones. The TR-EVOL module, that is devoted to fuel cycle mass balance, simulates diverse nuclear power plants (PWR, SFR, ADS, etc.), having possibly different types of fuels (UO_2, MOX, etc.), and the associated fuel cycle facilities (enrichment, fuel fabrication, processing, interim storage, waste storage, geological disposal). This work is intended to cross check the new capabilities of the fuel cycle scenario code TR-EVOL.This process has been divided in 2 stages. The first stage is dedicated to check the improvements in the nuclear fuel mass balance estimation using the available data for the Spanish nuclear fuel cycle. The second stage has been focused in verifying the validity of the TR-EVOL economic module, comparing results to data published by the ARCAS EU project. A specific analysis was required to evaluate the back-end cost. Data published by the waste management responsible institutions was used for the validation of the methodology. Results were highly satisfactory for both stages. In particular, the economic assessment provides a difference smaller than 3% regarding results published by the ARCAS project (NRG estimations). Furthermore, concerning the back-end cost, results are highly acceptable (7% difference for a final disposal in a once-through scenario and around 11% for a final disposal in a reprocessing strategy) given the significant uncertainties involved in design concepts and related unit costs. (authors)

  1. Performance investigation on a 4-bed adsorption desalination cycle with internal heat recovery scheme

    KAUST Repository

    Thu, Kyaw

    2016-10-08

    Multi-bed adsorption cycle with the internal heat recovery between the condenser and the evaporator is investigated for desalination application. A numerical model is developed for a 4-bed adsorption cycle implemented with the master-and-slave configuration and the aforementioned internal heat recovery scheme. The present model captures the reversed adsorption/desorption phenomena frequently associated with the unmatched switching periods. Mesoporous silica gel and water vapor emanated from the evaporation of the seawater are employed as the adsorbent and adsorbate pair. The experimental data and investigation for such configurations are reported for the first time at heat source temperatures from 50 °C to 70 °C. The numerical model is validated rigorously and the parametric study is conducted for the performance of the cycle at assorted operation conditions such as hot and cooling water inlet temperatures and the cycle times. The specific daily water production (SDWP) of the present cycle is found to be about 10 m/day per tonne of silica gel for the heat source temperature at 70 °C. Performance comparison is conducted for various types of adsorption desalination cycles. It is observed that the AD cycle with the current configuration provides superior performance whilst is operational at unprecedentedly low heat source temperature as low as 50 °C.

  2. Experiments and Cycling at the LHC Prototype Half-Cell

    Science.gov (United States)

    Saban, R.; Casas-Cubillos, J.; Coull, L.; Cruikshank, P.; Dahlerup-Petersen, K.; Hilbert, B.; Krainz, G.; Kos, N.; Lebrun, P.; Momal, F.; Misiaen, D.; Parma, V.; Poncet, A.; Riddone, G.; Rijllart, A.; Rodriguez-Mateos, F.; Schmidt, R.; Serio, L.; Wallen, E.; van Weelderen, R.; Williams, L. R.

    1997-05-01

    The first version of the LHC prototype half-cell has been in operation since February 1995. It consists of one quadrupole and three 10-m twin aperture dipole magnets which operate at 1.8 K. This experimental set-up has been used to observe and study phenomena which appear when the systems are assembled in one unit and influence one another. The 18-month long experimental program has validated the cryogenic system and yielded a number of results on cryogenic instrumentation, magnet protection and vacuum in particular under non-standard operating conditions. The program was recently complemented by the cycling experiment: it consisted in powering the magnets following the ramp rates which will be experienced by the magnets during an LHC injection. In order to simulate 10 years of routine operation of LHC, more than 2000 1-hour cycles were performed interleaved with provoked quenches. The objective of this experiment was to reveal eventual flaws in the design of components. The prototype half-cell performed to expectations showing no sign of failure of fatigue of components for more than 2000 cycles until one of the dipoles started exhibiting an erratic quench behavior.

  3. The feasibility study on commercialized fast reactor cycle system

    International Nuclear Information System (INIS)

    Noda, Hiroshi

    2002-01-01

    The feasibility study on commercialized Fast Reactor cycle system (FS) has been carried out by a joint team with the participation of all parties concerned in Japan since July, 1999. It aims to clarify various perspectives for commercialized fast reactor cycle system and also suggest development strategies to diverse social needs in the 21 st century. The FS consists of several phases. The phase 1 has progressed as planned and the highly feasible candidate concepts with innovative technologies have been screened out among a wide variety of concepts. During the phase 2, approximately five years after the phase 1, the in-depth design studies and engineering scale tests of key technologies are being conducted to verify and validate the feasibility of screened candidate concepts. At the end of the phase 2, a few promising concepts will be selected with their R and D tasks. The paper describes the results of the phase 1, the activities of the phase 2 and the new concept related to the fast reactor fuel cycle focusing on the reduction in environmental burden, which is one of key factors to sustain the nuclear power generation in the 21 st century

  4. Cáncer y terapéutica con productos de la colmena: Revisión sistemática de los estudios experimentales

    Directory of Open Access Journals (Sweden)

    Andrés Jagua Gualdrón

    2012-04-01

    Objetivo. Resumir la evidencia experimental disponible en la actualidad sobre el uso de los productos de la colmena en el manejo del cáncer. Material y métodos. Se realizó una revisión sistemática de los estudios experimentales publicados a través de las bibliotecas digitales PUBMED, LiLACS y OVID en los cuales se evaluara la utilidad del uso de los distintos productos de la colmena sobre cultivos de células tumorales o sobre modelos animales de cáncer. Se realizó un análisis cualitativo de la información y se construyeron tablas de resumen. Resultados. La búsqueda arrojó un total de 391 resultados de los cuales únicamente 55 cumplieron los criterios de inclusión. El veneno de abejas, la miel y el propóleo son los productos con un mayor número de publicaciones. La mayoría son estudios in vitro y son pocos los modelos en animales realizado. Se describen los mecanismos de acción a través de los cuales estos podrían llegar a ejercer acciones farmacológicas útiles en el manejo del cáncer. Conclusión. La aplicación de los productos de la colmena en el cáncer es un campo incipiente pero prometedor de investigación. Existe evidencia experimental que documenta la plausibilidad biológica de este uso. Es necesario realizar modelos animales que permitan describir el comportamiento de los productos y documentar su seguridad y utilidad terapéutica en el cáncer.

  5. Evaporative cycles - in theory and in practise

    Energy Technology Data Exchange (ETDEWEB)

    Rosen, P.M.

    2000-08-01

    The thesis is based on applied research, rather closed to industrial development. The developed simulation model, for pre-design of evaporative gas turbine cycles, has been validated in a 600 kW pilot plant and in rebuilt turbo-charged diesel engines. Besides of the work with the thesis including theoretical modelling and hardware development concerning wet cycles, the work has also resulted in three patents dealing with the technique studied. The main feature of the evaporative cycles is the way the integration between the gas and liquid flows is executed, combined with using low-level heat gathered into the liquid phase which is later used to evaporate the liquid itself in a humidification tower. In this tower, the mass- and heat transfer take place under stable physical laws, and if the tower is properly designed, the distilling effect in the tower will also be high. Today the combined cycle has the best thermal efficiency to generate electricity from fuels. Every new power cycle, including the evaporative cycles, will therefore be compared with power stations based on combined cycles. In evaporative cycles, the steam bottoming cycle of the combined cycles has been eliminated. Instead the 'steam' cycle is integrated into the gas cycle. This action has a favourable effect on thermal efficiency and on NO{sub x} formation in the combustion zone. The major part of this thesis is about the EvGT-project. At Lund University, the major objective of this project was to develop, design, erect and operate the world's first evaporative gas turbine unit. The objective was accomplished in 1999, and in the process of reaching the objective, rather large modelling errors, both thermodynamic and dimensioning of the humidification tower, have been detected in the open literature. It seems as if the pressure dependency of the humidification process has been underestimated in the models used today. The EvGT-pilot plant at Lund University was built and taken into

  6. Validation of the excore detector module of PANBOX 2

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Du Ill; Kang, Jung Kil; Hwang, Sun Tack [Korea Nuclear Fuel Company, Taejon (Korea, Republic of); Kim, Yeong Il [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of); Finnemann, H; Boer, R [Siemens/KWU N, Erlangen (Germany)

    1999-12-31

    In the PANBOX 2 system an excore detector module simulating the excore signal responses during a short term transient is implemented in order to simulate the reaction of the flux detector and control system upon rapid power changes as it occurs e. g., in rod drop events. This module has been verified in the past by comparison calculations with the PANBOX 1 system. This report describes additional PANBOX 2 validation calculations which have been compared with experimental data measured at german plant KKG, cycle 1, for a rod drop event. In general, the PANBOX 2 results are in very good agreement with the KKG experiments. Therefore it is concluded that the excore detector model of PANBOX 2 is successfully validated. 6 refs., 11 figs., 2 tabs. (Author)

  7. Validation of the excore detector module of PANBOX 2

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Du Ill; Kang, Jung Kil; Hwang, Sun Tack [Korea Nuclear Fuel Company, Taejon (Korea, Republic of); Kim, Yeong Il [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of); Finnemann, H; Boer, R. [Siemens/KWU N, Erlangen (Germany)

    1998-12-31

    In the PANBOX 2 system an excore detector module simulating the excore signal responses during a short term transient is implemented in order to simulate the reaction of the flux detector and control system upon rapid power changes as it occurs e. g., in rod drop events. This module has been verified in the past by comparison calculations with the PANBOX 1 system. This report describes additional PANBOX 2 validation calculations which have been compared with experimental data measured at german plant KKG, cycle 1, for a rod drop event. In general, the PANBOX 2 results are in very good agreement with the KKG experiments. Therefore it is concluded that the excore detector model of PANBOX 2 is successfully validated. 6 refs., 11 figs., 2 tabs. (Author)

  8. Development and validation of models for simulation of supercritical carbon dioxide Brayton cycles and application to self-propelling heat removal systems in boiling water reactors

    Energy Technology Data Exchange (ETDEWEB)

    Venker, Jeanne

    2015-03-31

    The objective of the current work was to develop a model that is able to describe the transient behavior of supercritical carbon dioxide (sCO{sub 2}) Brayton cycles, to be applied to self-propelling residual heat removal systems in boiling water reactors. The developed model has been implemented into the thermohydraulic system code ATHLET. By means of this improved ATHLET version, novel residual heat removal systems, which are based on closed sCO{sub 2} Brayton cycles, can be assessed as a retrofit measure for present light water reactors. Transient simulations are hereby of great importance. The heat removal system has to be modeled explicitly to account for the interaction between the system and the behavior of the plant during different accident conditions. As a first step, transport and thermodynamic fluid properties of supercritical carbon dioxide have been implemented in ATHLET to allow for the simulation of the new working fluid. Additionally, a heat transfer correlation has been selected to represent the specific heat transfer of supercritical carbon dioxide. For the calculation of pressure losses due to wall friction, an approach for turbulent single phase flow has been adopted that is already implemented in ATHLET. In a second step, a component model for radial compressors has been implemented in the system code. Furthermore, the available model for axial turbines has been adapted to simulate the transient behavior of radial turbines. All extensions have been validated against experimental data. In order to simulate the interaction between the self-propelling heat removal system and a generic boiling water reactor, the components of the sCO{sub 2} Brayton cycle have been dimensioned with first principles. An available input deck of a generic BWR has then been extended by the residual heat removal system. The modeled application has shown that the extended version of ATHLET is suitable to simulate sCO{sub 2} Brayton cycles and to evaluate the introduced

  9. High-potential Working Fluids for Next Generation Binary Cycle Geothermal Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Zia, Jalal [GE Global Research; Sevincer, Edip; Chen, Huijuan; Hardy, Ajilli; Wickersham, Paul; Kalra, Chiranjeev; Laursen, Anna Lis; Vandeputte, Thomas

    2013-06-29

    A thermo-economic model has been built and validated for prediction of project economics of Enhanced Geothermal Projects. The thermo-economic model calculates and iteratively optimizes the LCOE (levelized cost of electricity) for a prospective EGS (Enhanced Geothermal) site. It takes into account the local subsurface temperature gradient, the cost of drilling and reservoir creation, stimulation and power plant configuration. It calculates and optimizes the power plant configuration vs. well depth. Thus outputs from the model include optimal well depth and power plant configuration for the lowest LCOE. The main focus of this final report was to experimentally validate the thermodynamic properties that formed the basis of the thermo-economic model built in Phase 2, and thus build confidence that the predictions of the model could be used reliably for process downselection and preliminary design at a given set of geothermal (and/or waste heat) boundary conditions. The fluid and cycle downselected was based on a new proprietary fluid from a vendor in a supercritical ORC cycle at a resource condition of 200°C inlet temperature. The team devised and executed a series of experiments to prove the suitability of the new fluid in realistic ORC cycle conditions. Furthermore, the team performed a preliminary design study for a MW-scale turbo expander that would be used for a supercritical ORC cycle with this new fluid. The following summarizes the main findings in the investigative campaign that was undertaken: 1. Chemical compatibility of the new fluid with common seal/gasket/Oring materials was found to be problematic. Neoprene, Viton, and silicone materials were found to be incompatible, suffering chemical decomposition, swelling and/or compression set issues. Of the materials tested, only TEFLON was found to be compatible under actual ORC temperature and pressure conditions. 2. Thermal stability of the new fluid at 200°C and 40 bar was found to be acceptable after 399

  10. Evaluation of spectral shift controlled reactors operating on the uranium fuel cycle. Final report

    International Nuclear Information System (INIS)

    Matzie, R.A.; Sider, F.M.

    1979-08-01

    The performance of the spectral shift controlled reactor (SSCR) operating on uranium fuel cycles was evaluated and compared with the conventional pressurized water reactor (PWR). In order to analyze the SSCR, the PSR design methodology was extended to include systems moderated by mixtures of light water and heavy water and these methods were validated by comparison with experimental results. Once the design methods had been formulated, the resouce requirements and power costs were determined for the uranium-fueled SSCR. The ore requirements of the UO 2 once-through fuel cycle and the UO 2 fuel cycle with self-generated recycle (SGR) of plutonium were found to be 10% and 19% less than those of similarly fueled PWRs, respectively. A fuel cycle optimization study was performed for the UO 2 once-through SSCR and the SGR SSCR. By individually altering lattice parameters, discharge exposure or number of in-core batches, savings of less than 8% in resource requirements and less than 1% in power costs were obtained

  11. Optimum Envelope of a Single-Family House Based on Life Cycle Analysis

    Directory of Open Access Journals (Sweden)

    Marie-Claude Hamelin

    2014-04-01

    Full Text Available This paper describes the methodology used for the life cycle cost (LCC and life cycle energy (LCE analyses of the case study house in Quebec, Canada. The TRNSYS energy analysis program is coupled with GenOpt, a general purpose optimization program, for the purpose of this study. The particle swarm optimization (PSO algorithm is used for the search for the optimum solution. Results show that the optimum levels of insulation should be higher than the reference values, even for the case of LCC analysis. The results are for the most part still valid if electricity costs are assumed to increase below the inflation rate for the duration of the study period.

  12. A dynamic, dependent type system for nuclear fuel cycle code generation

    Energy Technology Data Exchange (ETDEWEB)

    Scopatz, A. [The University of Chicago 5754 S. Ellis Ave, Chicago, IL 60637 (United States)

    2013-07-01

    The nuclear fuel cycle may be interpreted as a network or graph, thus allowing methods from formal graph theory to be used. Nodes are often idealized as nuclear fuel cycle facilities (reactors, enrichment cascades, deep geologic repositories). With the advent of modern object-oriented programming languages - and fuel cycle simulators implemented in these languages - it is natural to define a class hierarchy of facility types. Bright is a quasi-static simulator, meaning that the number of material passes through a facility is tracked rather than natural time. Bright is implemented as a C++ library that models many canonical components such as reactors, storage facilities, and more. Cyclus is a discrete time simulator, meaning that natural time is tracked through out the simulation. Therefore a robust, dependent type system was developed to enable inter-operability between Bright and Cyclus. This system is capable of representing any fuel cycle facility. Types declared in this system can then be used to automatically generate code which binds a facility implementation to a simulator front end. Facility model wrappers may be used either internally to a fuel cycle simulator or as a mechanism for inter-operating multiple simulators. While such a tool has many potential use cases it has two main purposes: enabling easy performance of code-to-code comparisons and the verification and the validation of user input.

  13. Experimental demonstrations of organic Rankine cycle waste heat rejection systems

    Science.gov (United States)

    Bland, Timothy J.; Lacey, P. Douglas

    Two phase fluid management is an important factor in the successful design of organic Rankine cycle (ORC) power conversion systems for space applications. The evolution of the heat rejection system approach from a jet condenser, through a rotary jet condenser, to a rotary fluid management device (RFMD) with a surface condenser has been described in a previous paper. Some of the test programs that were used to prove the validity of the selected approach are described.

  14. Will Solar Cycles 25 and 26 Be Weaker than Cycle 24?

    Science.gov (United States)

    Javaraiah, J.

    2017-11-01

    The study of variations in solar activity is important for understanding the underlying mechanism of solar activity and for predicting the level of activity in view of the activity impact on space weather and global climate. Here we have used the amplitudes (the peak values of the 13-month smoothed international sunspot number) of Solar Cycles 1 - 24 to predict the relative amplitudes of the solar cycles during the rising phase of the upcoming Gleissberg cycle. We fitted a cosine function to the amplitudes and times of the solar cycles after subtracting a linear fit of the amplitudes. The best cosine fit shows overall properties (periods, maxima, minima, etc.) of Gleissberg cycles, but with large uncertainties. We obtain a pattern of the rising phase of the upcoming Gleissberg cycle, but there is considerable ambiguity. Using the epochs of violations of the Gnevyshev-Ohl rule (G-O rule) and the `tentative inverse G-O rule' of solar cycles during the period 1610 - 2015, and also using the epochs where the orbital angular momentum of the Sun is steeply decreased during the period 1600 - 2099, we infer that Solar Cycle 25 will be weaker than Cycle 24. Cycles 25 and 26 will have almost same strength, and their epochs are at the minimum between the current and upcoming Gleissberg cycles. In addition, Cycle 27 is expected to be stronger than Cycle 26 and weaker than Cycle 28, and Cycle 29 is expected to be stronger than both Cycles 28 and 30. The maximum of Cycle 29 is expected to represent the next Gleissberg maximum. Our analysis also suggests a much lower value (30 - 40) for the maximum amplitude of the upcoming Cycle 25.

  15. Culture in cycles: considering H.T. Odum's 'information cycle'

    Science.gov (United States)

    Abel, Thomas

    2014-01-01

    'Culture' remains a conundrum in anthropology. When recast in the mold of 'information cycles,' culture is transformed. New fault lines appear. Information is splintered into parallel or nested forms. Dynamics becomes cycling. Energy is essential. And culture has function in a directional universe. The 'information cycle' is the crowning component of H.T. Odum's theory of general systems. What follows is an application of the information cycle to the cultural domains of discourse, social media, ritual, education, journalism, technology, academia, and law, which were never attempted by Odum. In information cycles, cultural information is perpetuated - maintained against Second Law depreciation. Conclusions are that culture is in fact a nested hierarchy of cultural forms. Each scale of information production is semi-autonomous, with its own evolutionary dynamics of production and selection in an information cycle. Simultaneously, each information cycle is channeled or entrained by its larger scale of information and ultimately human-ecosystem structuring.

  16. Proliferation in cycle

    Energy Technology Data Exchange (ETDEWEB)

    Piao Yunsong [College of Physical Sciences, Graduate School of Chinese Academy of Sciences, Beijing 100049 (China)], E-mail: yspiao@gucas.ac.cn

    2009-06-15

    In the contracting phase with w{approx_equal}0, the scale invariant spectrum of curvature perturbation is given by the increasing mode of metric perturbation. In this Letter, it is found that if the contracting phase with w{approx_equal}0 is included in each cycle of a cycle universe, since the metric perturbation is amplified on super horizon scale cycle by cycle, after each cycle the universe will be inevitably separated into many parts independent of one another, each of which corresponds to a new universe and evolves up to next cycle, and then is separated again. In this sense, a cyclic multiverse scenario is actually presented, in which the universe proliferates cycle by cycle. We estimate the number of new universes proliferated in each cycle, and discuss the implications of this result.

  17. Proliferation in cycle

    International Nuclear Information System (INIS)

    Piao Yunsong

    2009-01-01

    In the contracting phase with w≅0, the scale invariant spectrum of curvature perturbation is given by the increasing mode of metric perturbation. In this Letter, it is found that if the contracting phase with w≅0 is included in each cycle of a cycle universe, since the metric perturbation is amplified on super horizon scale cycle by cycle, after each cycle the universe will be inevitably separated into many parts independent of one another, each of which corresponds to a new universe and evolves up to next cycle, and then is separated again. In this sense, a cyclic multiverse scenario is actually presented, in which the universe proliferates cycle by cycle. We estimate the number of new universes proliferated in each cycle, and discuss the implications of this result.

  18. Advanced Supercritical Carbon Dioxide Brayton Cycle Development

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, Mark [Univ. of Wisconsin, Madison, WI (United States); Sienicki, James [Argonne National Lab. (ANL), Argonne, IL (United States); Moisseytsev, Anton [Argonne National Lab. (ANL), Argonne, IL (United States); Nellis, Gregory [Univ. of Wisconsin, Madison, WI (United States); Klein, Sanford [Univ. of Wisconsin, Madison, WI (United States)

    2015-10-21

    Fluids operating in the supercritical state have promising characteristics for future high efficiency power cycles. In order to develop power cycles using supercritical fluids, it is necessary to understand the flow characteristics of fluids under both supercritical and two-phase conditions. In this study, a Computational Fluid Dynamic (CFD) methodology was developed for supercritical fluids flowing through complex geometries. A real fluid property module was implemented to provide properties for different supercritical fluids. However, in each simulation case, there is only one species of fluid. As a result, the fluid property module provides properties for either supercritical CO2 (S-CO2) or supercritical water (SCW). The Homogeneous Equilibrium Model (HEM) was employed to model the two-phase flow. HEM assumes two phases have same velocity, pressure, and temperature, making it only applicable for the dilute dispersed two-phase flow situation. Three example geometries, including orifices, labyrinth seals, and valves, were used to validate this methodology with experimental data. For the first geometry, S-CO2 and SCW flowing through orifices were simulated and compared with experimental data. The maximum difference between the mass flow rate predictions and experimental measurements is less than 5%. This is a significant improvement as previous works can only guarantee 10% error. In this research, several efforts were made to help this improvement. First, an accurate real fluid module was used to provide properties. Second, the upstream condition was determined by pressure and density, which determines supercritical states more precise than using pressure and temperature. For the second geometry, the flow through labyrinth seals was studied. After a successful validation, parametric studies were performed to study geometric effects on the leakage rate. Based on these parametric studies, an optimum design strategy for the see

  19. Proterozoic Milankovitch cycles and the history of the solar system.

    Science.gov (United States)

    Meyers, Stephen R; Malinverno, Alberto

    2018-06-19

    The geologic record of Milankovitch climate cycles provides a rich conceptual and temporal framework for evaluating Earth system evolution, bestowing a sharp lens through which to view our planet's history. However, the utility of these cycles for constraining the early Earth system is hindered by seemingly insurmountable uncertainties in our knowledge of solar system behavior (including Earth-Moon history), and poor temporal control for validation of cycle periods (e.g., from radioisotopic dates). Here we address these problems using a Bayesian inversion approach to quantitatively link astronomical theory with geologic observation, allowing a reconstruction of Proterozoic astronomical cycles, fundamental frequencies of the solar system, the precession constant, and the underlying geologic timescale, directly from stratigraphic data. Application of the approach to 1.4-billion-year-old rhythmites indicates a precession constant of 85.79 ± 2.72 arcsec/year (2σ), an Earth-Moon distance of 340,900 ± 2,600 km (2σ), and length of day of 18.68 ± 0.25 hours (2σ), with dominant climatic precession cycles of ∼14 ky and eccentricity cycles of ∼131 ky. The results confirm reduced tidal dissipation in the Proterozoic. A complementary analysis of Eocene rhythmites (∼55 Ma) illustrates how the approach offers a means to map out ancient solar system behavior and Earth-Moon history using the geologic archive. The method also provides robust quantitative uncertainties on the eccentricity and climatic precession periods, and derived astronomical timescales. As a consequence, the temporal resolution of ancient Earth system processes is enhanced, and our knowledge of early solar system dynamics is greatly improved.

  20. Women's preferences for men's beards show no relation to their ovarian cycle phase and sex hormone levels.

    Science.gov (United States)

    Dixson, Barnaby J W; Lee, Anthony J; Blake, Khandis R; Jasienska, Grazyna; Marcinkowska, Urszula M

    2018-01-01

    According to the ovulatory shift hypothesis, women's mate preferences for male morphology indicative of competitive ability, social dominance, and/or underlying health are strongest at the peri-ovulatory phase of the menstrual cycle. However, recent meta-analyses are divided on the robustness of such effects and the validity of the often-used indirect estimates of fertility and ovulation has been called into question in methodological studies. In the current study, we test whether women's preferences for men's beardedness, a cue of male sexual maturity, androgenic development and social dominance, are stronger at the peri-ovulatory phase of the menstrual cycle compared to during the early follicular or the luteal phase. We also tested whether levels of estradiol, progesterone, and the estradiol to progesterone ratio at each phase were associated with facial hair preferences. Fifty-two heterosexual women completed a two-alternative forced choice preference test for clean-shaven and bearded male faces during the follicular, peri-ovulatory (validated by the surge in luteinizing hormone or the drop in estradiol levels) and luteal phases. Participants also provided for one entire menstrual cycle daily saliva samples for subsequent assaying of estradiol and progesterone. Results showed an overall preference for bearded over clean-shaven faces at each phase of the menstrual cycle. However, preferences for facial hair were not significantly different over the phases of menstrual cycle and were not significantly associated with levels of reproductive hormones. We conclude that women's preferences for men's beardedness may not be related to changes in their likelihood of conception. Copyright © 2017 Elsevier Inc. All rights reserved.

  1. Soil Carbon and Nitrogen Cycle Modeling

    Science.gov (United States)

    Woo, D.; Chaoka, S.; Kumar, P.; Quijano, J. C.

    2012-12-01

    Second generation bioenergy crops, such as miscanthus (Miscantus × giganteus) and switchgrass (Panicum virgatum), are regarded as clean energy sources, and are an attractive option to mitigate the human-induced climate change. However, the global climate change and the expansion of perennial grass bioenergy crops have the power to alter the biogeochemical cycles in soil, especially, soil carbon storages, over long time scales. In order to develop a predictive understanding, this study develops a coupled hydrological-soil nutrient model to simulate soil carbon responses under different climate scenarios such as: (i) current weather condition, (ii) decreased precipitation by -15%, and (iii) increased temperature up to +3C for four different crops, namely miscanthus, switchgrass, maize, and natural prairie. We use Precision Agricultural Landscape Modeling System (PALMS), version 5.4.0, to capture biophysical and hydrological components coupled with a multilayer carbon and ¬nitrogen cycle model. We apply the model at daily time scale to the Energy Biosciences Institute study site, located in the University of Illinois Research Farms, in Urbana, Illinois. The atmospheric forcing used to run the model was generated stochastically from parameters obtained using available data recorded in Bondville Ameriflux Site. The model simulations are validated with observations of drainage and nitrate and ammonium concentrations recorded in drain tiles during 2011. The results of this study show (1) total soil carbon storage of miscanthus accumulates most noticeably due to the significant amount of aboveground plant carbon, and a relatively high carbon to nitrogen ratio and lignin content, which reduce the litter decomposition rate. Also, (2) the decreased precipitation contributes to the enhancement of total soil carbon storage and soil nitrogen concentration because of the reduced microbial biomass pool. However, (3) an opposite effect on the cycle is introduced by the increased

  2. Impact of New Transport Infrastructure on Walking, Cycling, and Physical Activity.

    Science.gov (United States)

    Panter, Jenna; Heinen, Eva; Mackett, Roger; Ogilvie, David

    2016-02-01

    Walking and cycling bring health and environmental benefits, but there is little robust evidence that changing the built environment promotes these activities in populations. This study evaluated the effects of new transport infrastructure on active commuting and physical activity. Quasi-experimental analysis nested within a cohort study. Four hundred and sixty-nine adult commuters, recruited through a predominantly workplace-based strategy, who lived within 30 kilometers of Cambridge, United Kingdom and worked in areas of the city to be served by the new transport infrastructure. The Cambridgeshire Guided Busway opened in 2011 and comprised a new bus network and a traffic-free walking and cycling route. Exposure to the intervention was defined using the shortest distance from each participant's home to the busway. Change in weekly time spent in active commuting between 2009 and 2012, measured by validated 7-day recall instrument. Secondary outcomes were changes in total weekly time spent walking and cycling and in recreational and overall physical activity, measured using the validated Recent Physical Activity Questionnaire. Data were analyzed in 2014. In multivariable multinomial regression models--adjusted for potential sociodemographic, geographic, health, and workplace confounders; baseline active commuting; and home or work relocation-exposure to the busway was associated with a significantly greater likelihood of an increase in weekly cycle commuting time (relative risk ratio=1.34, 95% CI=1.03, 1.76) and with an increase in overall time spent in active commuting among the least active commuters at baseline (relative risk ratio=1.76, 95% CI=1.16, 2.67). The study found no evidence of changes in recreational or overall physical activity. Providing new sustainable transport infrastructure was effective in promoting an increase in active commuting. These findings provide new evidence to support reconfiguring transport systems as part of public health improvement

  3. Static and dynamic modelling of gas turbines in advanced cycles

    Energy Technology Data Exchange (ETDEWEB)

    Gustafsson, Jan-Olof

    1998-12-01

    components. The models have been validated for simple cycle configuration. The dynamic model has been used for model experiments that reflect conditions under evaporative operation. The modelling of cooled gas turbines is important for the analysis of combined cycles and EvGT cycles. A static turbine airfoil cooling model, found in literature, is reviewed. It is then used to estimate average airfoil surface temperatures for an industrial gas turbine. All models in this thesis are based on sound thermodynamic principles and may be used for other applications as well 29 refs, 25 figs, 2 tabs

  4. Stochastic cost estimating in repository life-cycle cost analysis

    International Nuclear Information System (INIS)

    Tzemos, S.; Dippold, D.

    1986-01-01

    The conceptual development, the design, and the final construction and operation of a nuclear repository span many decades. Given this lengthy time frame, it is quite challenging to obtain a good approximation of the repository life-cycle cost. One can deal with this challenge by using an analytic method, the method of moments, to explicitly assess the uncertainty of the estimate. A series expansion is used to approximate the uncertainty distribution of the cost estimate. In this paper, the moment methodology is derived and is illustrated through a numerical example. The range of validity of the approximation is discussed. The method of moments is compared to the traditional stochastic cost estimating methods and found to provide more and better information on cost uncertainty. The tow methods converge to identical results as the number of convolved variables increases and approaches the range where the central limit theorem is valid

  5. A Combined High and Low Cycle Fatigue Model for Life Prediction of Turbine Blades

    Directory of Open Access Journals (Sweden)

    Shun-Peng Zhu

    2017-06-01

    Full Text Available Combined high and low cycle fatigue (CCF generally induces the failure of aircraft gas turbine attachments. Based on the aero-engine load spectrum, accurate assessment of fatigue damage due to the interaction of high cycle fatigue (HCF resulting from high frequency vibrations and low cycle fatigue (LCF from ground-air-ground engine cycles is of critical importance for ensuring structural integrity of engine components, like turbine blades. In this paper, the influence of combined damage accumulation on the expected CCF life are investigated for turbine blades. The CCF behavior of a turbine blade is usually studied by testing with four load-controlled parameters, including high cycle stress amplitude and frequency, and low cycle stress amplitude and frequency. According to this, a new damage accumulation model is proposed based on Miner’s rule to consider the coupled damage due to HCF-LCF interaction by introducing the four load parameters. Five experimental datasets of turbine blade alloys and turbine blades were introduced for model validation and comparison between the proposed Miner, Manson-Halford, and Trufyakov-Kovalchuk models. Results show that the proposed model provides more accurate predictions than others with lower mean and standard deviation values of model prediction errors.

  6. The Measurement of Maximal (Anaerobic Power Output on a Cycle Ergometer: A Critical Review

    Directory of Open Access Journals (Sweden)

    Tarak Driss

    2013-01-01

    Full Text Available The interests and limits of the different methods and protocols of maximal (anaerobic power ( assessment are reviewed: single all-out tests versus force-velocity tests, isokinetic ergometers versus friction-loaded ergometers, measure of during the acceleration phase or at peak velocity. The effects of training, athletic practice, diet and pharmacological substances upon the production of maximal mechanical power are not discussed in this review mainly focused on the technical (ergometer, crank length, toe clips, methodological (protocols and biological factors (muscle volume, muscle fiber type, age, gender, growth, temperature, chronobiology and fatigue limiting in cycling. Although the validity of the Wingate test is questionable, a large part of the review is dedicated to this test which is currently the all-out cycling test the most often used. The biomechanical characteristics specific of maximal and high speed cycling, the bioenergetics of the all-out cycling exercises and the influence of biochemical factors (acidosis and alkalosis, phosphate ions… are recalled at the beginning of the paper. The basic knowledge concerning the consequences of the force-velocity relationship upon power output, the biomechanics of sub-maximal cycling exercises and the study on the force-velocity relationship in cycling by Dickinson in 1928 are presented in Appendices.

  7. Applying the PDCA Cycle to the Complex Task of Teaching and Assessing Public Relations Writing

    Science.gov (United States)

    Knight, John E.; Allen, Sandra

    2012-01-01

    Teaching skills, knowledge and abilities appropriate for career-ready graduates and assessing learning are complex issues. Developing a valid and reliable approach is often by trial and error. Instead, the authors employed Deming's PDCA Cycle of continuous improvement as a systematic procedure to incrementally move closer to their goal. This paper…

  8. Monitoring long-lasting insecticidal net (LLIN) durability to validate net serviceable life assumptions, in Rwanda

    NARCIS (Netherlands)

    Hakizimana, E.; Cyubahiro, B.; Rukundo, A.; Kabayiza, A.; Mutabazi, A.; Beach, R.; Patel, R.; Tongren, J.E.; Karema, C.

    2014-01-01

    Background To validate assumptions about the length of the distribution–replacement cycle for long-lasting insecticidal nets (LLINs) in Rwanda, the Malaria and other Parasitic Diseases Division, Rwanda Ministry of Health, used World Health Organization methods to independently confirm the three-year

  9. Is the French fuel cycle management an asset for international business?

    International Nuclear Information System (INIS)

    Beutier, D.; Debes, M.

    2016-01-01

    In order to comfort its energy independence and diminish the amount of radioactive waste, France has chosen to close its fuel cycle since long. Thanks to the size of the fleet of reactors operating in France, reprocessing techniques have been validated on an industrial scale and France is now the only country to master these technologies. The French strategy of closing the fuel cycle allows, first, the vitrification of high-level radioactive wastes and their storing in passive installations before their definitive disposal and secondly, it allows the recycling of fissile materials. Several other countries like Japan, United-Kingdom, the Netherlands and China soon have also chosen to close their fuel cycle. Plutonium recycling is made through the fabrication of MOX (mixed uranium and plutonium oxides) fuel in the MELOX plant with an output of 120 tons a year. A second recycling of spent MOX fuel in PWR is unlikely because of the poor isotopic quality of the plutonium, the recycling will be possible and economically competitive in fast reactors when these 4. generation reactors take over. The important, complete and unique experience of AREVA in terms of fuel cycle from fuel fabrication to waste vitrification via plutonium recycling is a relevant asset in the competitive international nuclear energy market. (A.C.)

  10. Your Menstrual Cycle

    Science.gov (United States)

    ... your menstrual cycle What happens during your menstrual cycle The menstrual cycle includes not just your period, but the rise ... that take place over the weeks in your cycle. Want to know what happens on each day ...

  11. Restriction point control of the mammalian cell cycle via the cyclin E/Cdk2:p27 complex.

    NARCIS (Netherlands)

    Conradie, R.; Bruggeman, F.J.; Ciliberto, A.; Csikasz-Nagby, A.; Novak, B.; Westerhoff, H.V.; Snoep, J.L.

    2010-01-01

    Numerous top-down kinetic models have been constructed to describe the cell cycle. These models have typically been constructed, validated and analyzed using model species (molecular intermediates and proteins) and phenotypic observations, and therefore do not focus on the individual model processes

  12. Development, verification and validation of an FPGA-based core heat removal protection system for a PWR

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Yichun, E-mail: ycwu@xmu.edu.cn [College of Energy, Xiamen University, Xiamen 361102 (China); Shui, Xuanxuan, E-mail: 807001564@qq.com [College of Energy, Xiamen University, Xiamen 361102 (China); Cai, Yuanfeng, E-mail: 1056303902@qq.com [College of Energy, Xiamen University, Xiamen 361102 (China); Zhou, Junyi, E-mail: 1032133755@qq.com [College of Energy, Xiamen University, Xiamen 361102 (China); Wu, Zhiqiang, E-mail: npic_wu@126.com [State Key Laboratory of Reactor System Design Technology, Nuclear Power Institute of China, Chengdu 610041 (China); Zheng, Jianxiang, E-mail: zwu@xmu.edu.cn [College of Energy, Xiamen University, Xiamen 361102 (China)

    2016-05-15

    Highlights: • An example on life cycle development process and V&V on FPGA-based I&C is presented. • Software standards and guidelines are used in FPGA-based NPP I&C system logic V&V. • Diversified FPGA design and verification languages and tools are utilized. • An NPP operation principle simulator is used to simulate operation scenarios. - Abstract: To reach high confidence and ensure reliability of nuclear FPGA-based safety system, life cycle processes of discipline specification and implementation of design as well as regulations verification and validation (V&V) are needed. A specific example on how to conduct life cycle development process and V&V on FPGA-based core heat removal (CHR) protection system for CPR1000 pressure water reactor (PWR) is presented in this paper. Using the existing standards and guidelines for life cycle development and V&V, a simplified FPGA-based CHR protection system for PWR has been designed, implemented, verified and validated. Diversified verification and simulation languages and tools are used by the independent design team and the V&V team. In the system acceptance testing V&V phase, a CPR1000 NPP operation principle simulator (OPS) model is utilized to simulate normal and abnormal operation scenarios, and provide input data to the under-test FPGA-based CHR protection system and a verified C code CHR function module. The evaluation results are applied to validate the under-test FPGA-based CHR protection system. The OPS model operation outputs also provide reasonable references for the tests. Using an OPS model in the system acceptance testing V&V is cost-effective and high-efficient. A dedicated OPS, as a commercial-off-the-shelf (COTS) item, would contribute as an important tool in the V&V process of NPP I&C systems, including FPGA-based and microprocessor-based systems.

  13. The Impact of Different Instructional Strategies on Students' Understanding about the Cell Cycle in a General Education Biology Course

    Science.gov (United States)

    Krishnamurthy, Sanjana

    This study investigated the impact of different instructional strategies on students' understanding about the cell cycle in a general education biology course. Although several studies have documented gains in students' cell cycle understanding after instruction, these studies generally use only one instructional method, often without a comparison group. The goal of this study was to learn more about students' misconceptions about the cell cycle and how those ideas change after three different evidence-based learning experiences in undergraduate general education. Undergraduate students in six laboratory sections (n = 24; N = 144) in a large public institution in the western United States were surveyed pre- and post-instruction using a 14-item valid and reliable survey of cell cycle knowledge. Cronbach's alpha for the standard scoring convention was 0.264 and for the alternate scoring convention was 0.360, documenting serious problems with inconsistent validity and reliability of the survey. Operating as though the findings are at least a proxy for actual cell cycle knowledge, score comparisons by groups of interest were explored, including pre- and post-instruction differences among demographic groups of interest and three instructional settings: a bead modeling activity, a role-playing game, and 5E instructional strategy. No significant differences were found across groups of interest or by strategy, but some significant item-level differences were found. Implications and discussion of these shifts is noted in lieu of the literature.

  14. Fuel cycle cost uncertainty from nuclear fuel cycle comparison

    International Nuclear Information System (INIS)

    Li, J.; McNelis, D.; Yim, M.S.

    2013-01-01

    This paper examined the uncertainty in fuel cycle cost (FCC) calculation by considering both model and parameter uncertainty. Four different fuel cycle options were compared in the analysis including the once-through cycle (OT), the DUPIC cycle, the MOX cycle and a closed fuel cycle with fast reactors (FR). The model uncertainty was addressed by using three different FCC modeling approaches with and without the time value of money consideration. The relative ratios of FCC in comparison to OT did not change much by using different modeling approaches. This observation was consistent with the results of the sensitivity study for the discount rate. Two different sets of data with uncertainty range of unit costs were used to address the parameter uncertainty of the FCC calculation. The sensitivity study showed that the dominating contributor to the total variance of FCC is the uranium price. In general, the FCC of OT was found to be the lowest followed by FR, MOX, and DUPIC. But depending on the uranium price, the FR cycle was found to have lower FCC over OT. The reprocessing cost was also found to have a major impact on FCC

  15. Reliability and validity of the transport and physical activity questionnaire (TPAQ for assessing physical activity behaviour.

    Directory of Open Access Journals (Sweden)

    Emma J Adams

    Full Text Available No current validated survey instrument allows a comprehensive assessment of both physical activity and travel behaviours for use in interdisciplinary research on walking and cycling. This study reports on the test-retest reliability and validity of physical activity measures in the transport and physical activity questionnaire (TPAQ.The TPAQ assesses time spent in different domains of physical activity and using different modes of transport for five journey purposes. Test-retest reliability of eight physical activity summary variables was assessed using intra-class correlation coefficients (ICC and Kappa scores for continuous and categorical variables respectively. In a separate study, the validity of three survey-reported physical activity summary variables was assessed by computing Spearman correlation coefficients using accelerometer-derived reference measures. The Bland-Altman technique was used to determine the absolute validity of survey-reported time spent in moderate-to-vigorous physical activity (MVPA.In the reliability study, ICC for time spent in different domains of physical activity ranged from fair to substantial for walking for transport (ICC = 0.59, cycling for transport (ICC = 0.61, walking for recreation (ICC = 0.48, cycling for recreation (ICC = 0.35, moderate leisure-time physical activity (ICC = 0.47, vigorous leisure-time physical activity (ICC = 0.63, and total physical activity (ICC = 0.56. The proportion of participants estimated to meet physical activity guidelines showed acceptable reliability (k = 0.60. In the validity study, comparison of survey-reported and accelerometer-derived time spent in physical activity showed strong agreement for vigorous physical activity (r = 0.72, p<0.001, fair but non-significant agreement for moderate physical activity (r = 0.24, p = 0.09 and fair agreement for MVPA (r = 0.27, p = 0.05. Bland-Altman analysis showed a mean

  16. Reliability and Validity of the Transport and Physical Activity Questionnaire (TPAQ) for Assessing Physical Activity Behaviour

    Science.gov (United States)

    Adams, Emma J.; Goad, Mary; Sahlqvist, Shannon; Bull, Fiona C.; Cooper, Ashley R.; Ogilvie, David

    2014-01-01

    Background No current validated survey instrument allows a comprehensive assessment of both physical activity and travel behaviours for use in interdisciplinary research on walking and cycling. This study reports on the test-retest reliability and validity of physical activity measures in the transport and physical activity questionnaire (TPAQ). Methods The TPAQ assesses time spent in different domains of physical activity and using different modes of transport for five journey purposes. Test-retest reliability of eight physical activity summary variables was assessed using intra-class correlation coefficients (ICC) and Kappa scores for continuous and categorical variables respectively. In a separate study, the validity of three survey-reported physical activity summary variables was assessed by computing Spearman correlation coefficients using accelerometer-derived reference measures. The Bland-Altman technique was used to determine the absolute validity of survey-reported time spent in moderate-to-vigorous physical activity (MVPA). Results In the reliability study, ICC for time spent in different domains of physical activity ranged from fair to substantial for walking for transport (ICC = 0.59), cycling for transport (ICC = 0.61), walking for recreation (ICC = 0.48), cycling for recreation (ICC = 0.35), moderate leisure-time physical activity (ICC = 0.47), vigorous leisure-time physical activity (ICC = 0.63), and total physical activity (ICC = 0.56). The proportion of participants estimated to meet physical activity guidelines showed acceptable reliability (k = 0.60). In the validity study, comparison of survey-reported and accelerometer-derived time spent in physical activity showed strong agreement for vigorous physical activity (r = 0.72, pphysical activity (r = 0.24, p = 0.09) and fair agreement for MVPA (r = 0.27, p = 0.05). Bland-Altman analysis showed a mean overestimation of MVPA of 87.6 min/week (p

  17. Development of the ANL plant dynamics code and control strategies for the supercritical carbon dioxide Brayton cycle and code validation with data from the Sandia small-scale supercritical carbon dioxide Brayton cycle test loop.

    Energy Technology Data Exchange (ETDEWEB)

    Moisseytsev, A.; Sienicki, J. J. (Nuclear Engineering Division)

    2011-11-07

    Significant progress has been made in the ongoing development of the Argonne National Laboratory (ANL) Plant Dynamics Code (PDC), the ongoing investigation and development of control strategies, and the analysis of system transient behavior for supercritical carbon dioxide (S-CO{sub 2}) Brayton cycles. Several code modifications have been introduced during FY2011 to extend the range of applicability of the PDC and to improve its calculational stability and speed. A new and innovative approach was developed to couple the Plant Dynamics Code for S-CO{sub 2} cycle calculations with SAS4A/SASSYS-1 Liquid Metal Reactor Code System calculations for the transient system level behavior on the reactor side of a Sodium-Cooled Fast Reactor (SFR) or Lead-Cooled Fast Reactor (LFR). The new code system allows use of the full capabilities of both codes such that whole-plant transients can now be simulated without additional user interaction. Several other code modifications, including the introduction of compressor surge control, a new approach for determining the solution time step for efficient computational speed, an updated treatment of S-CO{sub 2} cycle flow mergers and splits, a modified enthalpy equation to improve the treatment of negative flow, and a revised solution of the reactor heat exchanger (RHX) equations coupling the S-CO{sub 2} cycle to the reactor, were introduced to the PDC in FY2011. All of these modifications have improved the code computational stability and computational speed, while not significantly affecting the results of transient calculations. The improved PDC was used to continue the investigation of S-CO{sub 2} cycle control and transient behavior. The coupled PDC-SAS4A/SASSYS-1 code capability was used to study the dynamic characteristics of a S-CO{sub 2} cycle coupled to a SFR plant. Cycle control was investigated in terms of the ability of the cycle to respond to a linear reduction in the electrical grid demand from 100% to 0% at a rate of 5

  18. Radioactive materials transportation life-cycle cost

    International Nuclear Information System (INIS)

    Gregory, P.C.; Donovan, K.S.; Spooner, O.R.

    1993-01-01

    This paper discusses factors that should be considered when estimating the life-cycle cost of shipping radioactive materials and the development of a working model that has been successfully used. Today's environmental concerns have produced an increased emphasis on cleanup and restoration of production plants and interim storage sites for radioactive materials. The need to transport these radioactive materials to processing facilities or permanent repositories is offset by the reality of limited resources and ever-tightening budgets. Obtaining the true cost of transportation is often difficult because of the many direct and indirect costs involved and the variety of methods used to account for fixed and variable expenses. In order to make valid comparisons between the cost of alternate transportation systems for new and/or existing programs, one should consider more than just the cost of capital equipment or freight cost per mile. Of special interest is the cost of design, fabrication, use, and maintenance of shipping containers in accordance with the requirements of the U.S. Nuclear Regulatory Commission. A spread sheet model was developed to compare the life-cycle costs of alternate fleet configurations of TRUPACT-II, which will be used to ship transuranic waste from U.S. Department of Energy sites to the Waste Isolation Pilot Plant near Carlsbad, New Mexico

  19. DETECTING ALIEN LIMIT CYCLES NEAR A HAMILTONIAN 2-SADDLE CYCLE

    OpenAIRE

    LUCA, Stijn; DUMORTIER, Freddy; Caubergh, M.; Roussarie, R.

    2009-01-01

    This paper aims at providing and example of a cubic Hamiltonian 2-saddle cycle that after bifurcation can give rise to an alien limit cycle; this is a limit cycle that is not controlled by a zero of the related Abelian integral. To guarantee the existence of an alien limit cycle one can verify generic conditions on the Abelian integral and on the transition map associated to the connections of the 2-saddle cycle. In this paper, a general method is developed to compute the first and second der...

  20. High-cycle electromechanical aging of dielectric elastomer actuators with carbon-based electrodes

    Science.gov (United States)

    de Saint-Aubin, C. A.; Rosset, S.; Schlatter, S.; Shea, H.

    2018-07-01

    We present high-cycle aging tests of dielectric elastomer actuators (DEAs) based on silicone elastomers, reporting on the time-evolution of actuation strain and of electrode resistance over millions of cycles. We compare several types of carbon-based electrodes, and for the first time show how the choice of electrode has a dramatic influence on DEA aging. An expanding circle DEA configuration is used, consisting of a commercial silicone membrane with the following electrodes: commercial carbon grease applied manually, solvent-diluted carbon grease applied by stamping (pad printing), loose carbon black powder applied manually, carbon black powder suspension applied by inkjet-printing, and conductive silicone-carbon composite applied by stamping. The silicone-based DEAs with manually applied carbon grease electrodes show the shortest lifetime of less than 105 cycles at 5% strain, while the inkjet-printed carbon powder and the stamped silicone-carbon composite make for the most reliable devices, with lifetimes greater than 107 cycles at 5% strain. These results are valid for the specific dielectric and electrode configurations that were tested: using other dielectrics or electrode formulations would lead to different lifetimes and failure modes. We find that aging (as seen in the change in resistance and in actuation strain versus cycle number) is independent of the actuation frequency from 10 Hz to 200 Hz, and depends on the total accumulated time the DEA spends in an actuated state.

  1. Empirical evidence for stability of the 405-kiloyear Jupiter-Venus eccentricity cycle over hundreds of millions of years.

    Science.gov (United States)

    Kent, Dennis V; Olsen, Paul E; Rasmussen, Cornelia; Lepre, Christopher; Mundil, Roland; Irmis, Randall B; Gehrels, George E; Giesler, Dominique; Geissman, John W; Parker, William G

    2018-06-12

    The Newark-Hartford astrochronostratigraphic polarity timescale (APTS) was developed using a theoretically constant 405-kiloyear eccentricity cycle linked to gravitational interactions with Jupiter-Venus as a tuning target and provides a major timing calibration for about 30 million years of Late Triassic and earliest Jurassic time. While the 405-ky cycle is both unimodal and the most metronomic of the major orbital cycles thought to pace Earth's climate in numerical solutions, there has been little empirical confirmation of that behavior, especially back before the limits of orbital solutions at about 50 million years before present. Moreover, the APTS is anchored only at its younger end by U-Pb zircon dates at 201.6 million years before present and could even be missing a number of 405-ky cycles. To test the validity of the dangling APTS and orbital periodicities, we recovered a diagnostic magnetic polarity sequence in the volcaniclastic-bearing Chinle Formation in a scientific drill core from Petrified Forest National Park (Arizona) that provides an unambiguous correlation to the APTS. New high precision U-Pb detrital zircon dates from the core are indistinguishable from ages predicted by the APTS back to 215 million years before present. The agreement shows that the APTS is continuous and supports a stable 405-kiloyear cycle well beyond theoretical solutions. The validated Newark-Hartford APTS can be used as a robust framework to help differentiate provinciality from global temporal patterns in the ecological rise of early dinosaurs in the Late Triassic, amongst other problems.

  2. Proposal of a nuclear cycle research and development plan in Tokai works. The roadmap from LWR cycle to FBR cycle

    International Nuclear Information System (INIS)

    Nakamura, Hirofumi; Abe, Tomoyuki; Kashimura, Takuo; Nagai, Toshihisa; Maeda, Seichiro; Yamaguchi, Toshiya; Kuroki, Ryoichiro

    2003-07-01

    The Generation-II Project Task Force Team has investigated a research and development plan of a future nuclear fuel cycle in Tokai works for about three months from December 19, 2002. First we have discussed about the present condition of Japanese nuclear fuel cycle and have recognized it as the following. The relation of the technology between the LWR-cycle and the FBR-cycle is not clear. MOX Fuel Use in Light Water Reactors is important to establish technology of the FBR fuel cycle. Radioactive waste disposal issue is urgent. Next we have proposed the three basic policies on R and D plan of nuclear fuel cycle in consideration of the F.S. on FBR-cycle. Establishment and advancement of 'the tough nuclear fuel cycle'. Early establishment of the FBR cycle technology to be able to supply energy stably for long-term. Establishment of the radioactive waste treatment and disposal technology, and optimization of nuclear fuel cycle technology from the viewpoint of radioactive waste. And we have proposed the Japanese technical holder system to integrate all LWR and FBR cycle technology. (author)

  3. Simulation of Cycle-to-Cycle Variation in Dual-Fuel Engines

    KAUST Repository

    Jaasim, Mohammed

    2017-03-13

    Standard practices of internal combustion (IC) engine experiments are to conduct the measurements of quantities averaged over a large number of cycles. Depending on the operating conditions, the cycle-to-cycle variation (CCV) of quantities, such as the indicated mean effective pressure (IMEP) are observed at different levels. Accurate prediction of CCV in IC engines is an important but challenging task. Computational fluid dynamics (CFD) simulations using high performance computing (HPC) can be used effectively to visualize such 3D spatial distributions. In the present study, a dual fuel large engine is considered, with natural gas injected into the manifold accompanied with direct injection of diesel pilot fuel to trigger ignition. Multiple engine cycles in 3D are simulated in series as in the experiments to investigate the potential of HPC based high fidelity simulations to accurately capture the cycle to cycle variation in dual fuel engines. Open cycle simulations are conducted to predict the combined effect of the stratification of fuel-air mixture, temperature and turbulence on the CCV of pressure. The predicted coefficient of variation (COV) of pressure compared to the results from closed cycle simulations and the experiments.

  4. Validation of a Measure of Family Resilience among Iraq and Afghanistan Veterans.

    Science.gov (United States)

    Finley, Erin P; Pugh, Mary Jo; Palmer, Raymond F

    2016-01-01

    Although interactions within veterans' families may support or inhibit resilient coping to stress and trauma across the deployment cycle, research on family resilience has been hampered by the lack of a brief assessment. Using a three-stage mixed-method study, we developed and conducted preliminary validation of a measure of family resilience tailored for Iraq and Afghanistan veterans (IAV), the Family Resilience Scale for Veterans (FRS-V) , which was field-tested using a survey of 151 IAV. Our findings indicate the resulting 6-item measure shows strong initial reliability and validity and support the application of existing models of family resilience in this population.

  5. Pressure cycling monitoring helps ensure the integrity of energy pipelines

    Energy Technology Data Exchange (ETDEWEB)

    Song, Peter; Lawrence, Doug; Keane, Sean; Ironside, Scott; Sutton, Aaron [Enbridge Pipelines Inc., Edmonton, AB (Canada)

    2010-07-01

    Enbridge Pipelines Inc. undertook a pressure cycling monitoring (PCM) program to see how pressure cycling severity (PCS) changes during line operations. The main purpose of this program is to make sure the integrity assessment interval is valid and to identify changes in operations that cause fatigue damage. The estimated fatigue life is obtained through fatigue analysis, which is based on Paris Law and uses certain data such as the operating pressure data from Enbridge's SCADA system. It serves as a measure of the PCS. When applied in an integrity management program, PCM helps maintain the integrity of pipelines by pinpointing segments whose operations have changed significantly. Among useful conclusions, it was found that a comparison between crack threat susceptibility indicators and PCS fluctuations help identify a change to crack threat susceptibility; also, the program helps identify notable changes to PCS that are caused by certain operational practices.

  6. Development and application of methods and computer codes of fuel management and nuclear design of reload cycles in PWR

    International Nuclear Information System (INIS)

    Ahnert, C.; Aragones, J.M.; Corella, M.R.; Esteban, A.; Martinez-Val, J.M.; Minguez, E.; Perlado, J.M.; Pena, J.; Matias, E. de; Llorente, A.; Navascues, J.; Serrano, J.

    1976-01-01

    Description of methods and computer codes for Fuel Management and Nuclear Design of Reload Cycles in PWR, developed at JEN by adaptation of previous codes (LEOPARD, NUTRIX, CITATION, FUELCOST) and implementation of original codes (TEMP, SOTHIS, CICLON, NUDO, MELON, ROLLO, LIBRA, PENELOPE) and their application to the project of Management and Design of Reload Cycles of a 510 Mwt PWR, including comparison with results of experimental operation and other calculations for validation of methods. (author) [es

  7. Validation test of advanced technology for IPV nickel-hydrogen flight cells - Update

    Science.gov (United States)

    Smithrick, John J.; Hall, Stephen W.

    1992-01-01

    Individual pressure vessel (IPV) nickel-hydrogen technology was advanced at NASA Lewis and under Lewis contracts with the intention of improving cycle life and performance. One advancement was to use 26 percent potassium hydroxide (KOH) electrolyte to improve cycle life. Another advancement was to modify the state-of-the-art cell design to eliminate identified failure modes. The modified design is referred to as the advanced design. A breakthrough in the LEO cycle life of IPV nickel-hydrogen cells has been previously reported. The cycle life of boiler plate cells containing 26 percent KOH electrolyte was about 40,000 LEO cycles compared to 3,500 cycles for cells containing 31 percent KOH. The boiler plate test results are in the process of being validated using flight hardware and real time LEO testing. The primary function of the advanced cell is to store and deliver energy for long-term, LEO spacecraft missions. The new features of this design are: (1) use of 26 percent rather than 31 percent KOH electrolyte; (2) use of a patented catalyzed wall wick; (3) use of serrated-edge separators to facilitate gaseous oxygen and hydrogen flow within the cell, while still maintaining physical contact with the wall wick for electrolyte management; and (4) use of a floating rather than a fixed stack (state-of-the-art) to accommodate nickel electrode expansion due to charge/discharge cycling. The significant improvements resulting from these innovations are: extended cycle life; enhanced thermal, electrolyte, and oxygen management; and accommodation of nickel electrode expansion.

  8. Simulation of Cycle-to-Cycle Variation in Dual-Fuel Engines

    KAUST Repository

    Jaasim, Mohammed; Pasunurthi, Shyamsundar; Jupudi, Ravichandra S.; Gubba, Sreenivasa Rao; Primus, Roy; Klingbeil, Adam; Wijeyakulasuriya, Sameera; Im, Hong G.

    2017-01-01

    Standard practices of internal combustion (IC) engine experiments are to conduct the measurements of quantities averaged over a large number of cycles. Depending on the operating conditions, the cycle-to-cycle variation (CCV) of quantities

  9. Life-cycle cost analysis of adsorption cycles for desalination

    KAUST Repository

    Thu, Kyaw

    2010-08-01

    This paper presents the thermo-economic analysis of the adsorption desalination (AD) cycle that is driven by low-temperature waste heat from exhaust of industrial processes or renewable sources. The AD cycle uses an adsorbent such as the silica gel to desalt the sea or brackish water. Based on an experimental prototype AD plant, the life-cycle cost analysis of AD plants of assorted water production capacities has been simulated and these predictions are translated into unit cost of water production. Our results show that the specific energy consumption of the AD cycle is 1.38 kWh/m3 which is the lowest ever reported. For a plant capacity of 1000 m3/d, the AD cycle offers a unit cost of $0.457/m3 as compared to more than $0.9 for the average RO plants. Besides being cost-effective, the AD cycle is also environment-friendly as it emits less CO2 emission per m3 generated, typically 85% less, by comparison to an RO process. © 2010 Desalination Publications.

  10. Prolonged menstrual cycles in female workers exposed to ethylene glycol ethers in the semiconductor manufacturing industry.

    Science.gov (United States)

    Hsieh, G-Y; Wang, J-D; Cheng, T-J; Chen, P-C

    2005-08-01

    It has been shown that female workers exposed to ethylene glycol ethers (EGEs) in the semiconductor industry have higher risks of spontaneous abortion, subfertility, and menstrual disturbances, and prolonged waiting time to pregnancy. To examine whether EGEs or other chemicals are associated with long menstrual cycles in female workers in the semiconductor manufacturing industry. Cross-sectional questionnaire survey during the annual health examination at a wafer manufacturing company in Taiwan in 1997. A three tiered exposure-assessment strategy was used to analyse the risk. A short menstrual cycle was defined to be a cycle less than 24 days and a long cycle to be more than 35 days. There were 606 valid questionnaires from 473 workers in fabrication jobs and 133 in non-fabrication areas. Long menstrual cycles were associated with workers in fabrication areas compared to those in non-fabrication areas. Using workers in non-fabrication areas as referents, workers in photolithography and diffusion areas had higher risks for long menstrual cycles. Workers exposed to EGEs and isopropanol, and hydrofluoric acid, isopropanol, and phosphorous compounds also showed increased risks of a long menstrual cycle. Exposure to multiple chemicals, including EGEs in photolithography, might be associated with long menstrual cycles, and may play an important role in a prolonged time to pregnancy in the wafer manufacturing industry; however, the prevalence in the design, possible exposure misclassification, and chance should be considered.

  11. Instantaneous charging & discharging cycle analysis of a novel supercapacitor based energy harvesting circuit

    Science.gov (United States)

    Khan, MD Shahrukh Adnan; Kuni, Sharsad Kara; Rajkumar, Rajprasad; Syed, Anas; Hawladar, Masum; Rahman, Md. Moshiur

    2017-12-01

    In this paper, an extensive effort has been made to design and develop a prototype in a laboratory setup environment in order to investigate experimentally the response of a novel Supercapacitor based energy harvesting circuit; particularly the phenomena of instantaneous charging and discharging cycle is analysed. To maximize battery lifespan and storage capacity, charging/discharging cycles need to be optimized in such a way, it ultimately enhances the system performances reliably. Keeping this into focus, an Arduino-MOSFET based control system is developed to charge the Supercapacitor from a low wind Vertical Axis Turbine (VAWT) and discharge it through a 6V battery. With a wind speed of 5m/s, the wind turbine requires approximately 8.1 hours to charge the 6V battery through Supercapacitor bank that constitutes 18 cycles in which each cycle consumes 27 minutes. The overall performance of the proposed system was quite convincing in a sense that the efficiency of the developed Energy Harvesting Circuit EHC raises to 19% in comparison to direct charging of the battery from the Vertical wind turbine. At low wind speed, such value of efficiency margin is quite encouraging which essentially validates the system design.

  12. The change of radial power factor distribution due to RCCA insertion at the first cycle core of AP1000

    Science.gov (United States)

    Susilo, J.; Suparlina, L.; Deswandri; Sunaryo, G. R.

    2018-02-01

    The using of a computer program for the PWR type core neutronic design parameters analysis has been carried out in some previous studies. These studies included a computer code validation on the neutronic parameters data values resulted from measurements and benchmarking calculation. In this study, the AP1000 first cycle core radial power peaking factor validation and analysis were performed using CITATION module of the SRAC2006 computer code. The computer code has been also validated with a good result to the criticality values of VERA benchmark core. The AP1000 core power distribution calculation has been done in two-dimensional X-Y geometry through ¼ section modeling. The purpose of this research is to determine the accuracy of the SRAC2006 code, and also the safety performance of the AP1000 core first cycle operating. The core calculations were carried out with the several conditions, those are without Rod Cluster Control Assembly (RCCA), by insertion of a single RCCA (AO, M1, M2, MA, MB, MC, MD) and multiple insertion RCCA (MA + MB, MA + MB + MC, MA + MB + MC + MD, and MA + MB + MC + MD + M1). The maximum power factor of the fuel rods value in the fuel assembly assumedapproximately 1.406. The calculation results analysis showed that the 2-dimensional CITATION module of SRAC2006 code is accurate in AP1000 power distribution calculation without RCCA and with MA+MB RCCA insertion.The power peaking factor on the first operating cycle of the AP1000 core without RCCA, as well as with single and multiple RCCA are still below in the safety limit values (less then about 1.798). So in terms of thermal power generated by the fuel assembly, then it can be considered that the AP100 core at the first operating cycle is safe.

  13. How well can business cycle accounting account for business cycles?

    OpenAIRE

    Keisuke Otsu

    2012-01-01

    The business cycle accounting method introduced by Chari, Kehoe and McGrattan (2007) is a useful tool to decompose business cycle fluctuations into their contributing factors. However, the model estimated by the maximum likelihood method cannot replicate business cycle moments computed from data. Moment-based estimation might be an attractive alternative if the purpose of the research is to study business cycle properties such as volatility, persistence and cross-correlation of variables inst...

  14. Quasi-static Cycle Performance Analysis of Micro Modular Reactor for Heat Sink Temperature Variation

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Seong Kuk; Lee, Jekyoung; Ahn, Yoonhan; Lee, Jeong Ik [KAIST, Daejeon (Korea, Republic of); Cha, Jae Eun [KAERI, Daejeon (Korea, Republic of)

    2015-10-15

    A Supercritical CO{sub 2} (S-CO{sub 2}) cycle has potential for high thermal efficiency in the moderate turbine inlet temperature (450 - 750 .deg. C) and achieving compact system size because of small specific volume and simple cycle layouts. Owing to small specific volume of S-CO{sub 2} and the development of heat exchanger technology, it can accomplish complete modularization of the system. The previous works focused on the cycle performance analysis for the design point only. However, the heat sink temperature can be changed depending on the ambient atmosphere condition, i.e. weather, seasonal change. This can influence the compressor inlet temperature, which alters the cycle operating condition overall. To reflect the heat sink temperature variation, a quasi-static analysis code for a simple recuperated S-CO{sub 2} Brayton cycle has been developed by the KAIST research team. Thus, cycle performance analysis is carried out with a compressor inlet temperature variation in this research. In the case of dry air-cooling system, the ambient temperature of the local surrounding can affect the compressor inlet temperature. As the compressor inlet temperature increases, thermal efficiency and generated electricity decrease. As further works, the experiment of S-CO{sub 2} integral test loop will be performed to validate in-house codes, such as KAIST{sub T}MD and the quasi-static code.

  15. Modeling and simulation of syngas purification and power generation in integrated gasification combined cycle (IGCS)

    Energy Technology Data Exchange (ETDEWEB)

    Mehmood, N; Zaman, Z U; Mehran, M T [National Development, Islamabad (Pakistan)

    2011-07-01

    Integrated Gasification Combined Cycle (IGCC) is one of the most promising technologies for power generation; The environmental benefits and the higher energy conversion efficiency distinguish it from traditional coal generation technologies. This work presents a structured and validated conceptual model of purification of coal gas produced during the Underground Coal Gasification (UCG) of coal containing high sulfur contents. Gas cleaning operations for CO/sub 2/, H/sub 2/S and moisture removal have been modeled in steady and dynamic state. The power generation from combined cycle is also modeled. The model has been developed using Aspen HYSYS and Aspen Plus simulation software. Predicted results of clean gas composition and generated power present a good agreement with industrial data and efficiency parameters. This study is aimed at obtaining optimal assessment of an integrated gasification combined cycle (IGCC) power plant configurations. (author)

  16. Modeling and simulation of syngas purification and power generation in integrated gasification combined cycle (IGCS)

    International Nuclear Information System (INIS)

    Mehmood, N.; Zaman, Z.U.; Mehran, M.T.

    2011-01-01

    Integrated Gasification Combined Cycle (IGCC) is one of the most promising technologies for power generation; The environmental benefits and the higher energy conversion efficiency distinguish it from traditional coal generation technologies. This work presents a structured and validated conceptual model of purification of coal gas produced during the Underground Coal Gasification (UCG) of coal containing high sulfur contents. Gas cleaning operations for CO/sub 2/, H/sub 2/S and moisture removal have been modeled in steady and dynamic state. The power generation from combined cycle is also modeled. The model has been developed using Aspen HYSYS and Aspen Plus simulation software. Predicted results of clean gas composition and generated power present a good agreement with industrial data and efficiency parameters. This study is aimed at obtaining optimal assessment of an integrated gasification combined cycle (IGCC) power plant configurations. (author)

  17. Vce-based methods for temperature estimation of high power IGBT modules during power cycling - A comparison

    DEFF Research Database (Denmark)

    Amoiridis, Anastasios; Anurag, Anup; Ghimire, Pramod

    2015-01-01

    . This experimental work evaluates the validity and accuracy of two Vce based methods applied on high power IGBT modules during power cycling tests. The first method estimates the chip temperature when low sense current is applied and the second method when normal load current is present. Finally, a correction factor......Temperature estimation is of great importance for performance and reliability of IGBT power modules in converter operation as well as in active power cycling tests. It is common to be estimated through Thermo-Sensitive Electrical Parameters such as the forward voltage drop (Vce) of the chip...

  18. Cycling in Sydney, Australia

    Directory of Open Access Journals (Sweden)

    Alexis Zander

    2013-01-01

    Full Text Available Introduction. Cycling can be an enjoyable way to meet physical activity recommendations and is suitable for older people; however cycling participation by older Australians is low. This qualitative study explored motivators, enablers, and barriers to cycling among older people through an age-targeted cycling promotion program. Methods. Seventeen adults who aged 50–75 years participated in a 12-week cycling promotion program which included a cycling skills course, mentor, and resource pack. Semistructured interviews at the beginning and end of the program explored motivators, enablers, and barriers to cycling. Results. Fitness and recreation were the primary motivators for cycling. The biggest barrier was fear of cars and traffic, and the cycling skills course was the most important enabler for improving participants’ confidence. Reported outcomes from cycling included improved quality of life (better mental health, social benefit, and empowerment and improved physical health. Conclusions. A simple cycling program increased cycling participation among older people. This work confirms the importance of improving confidence in this age group through a skills course, mentors, and maps and highlights additional strategies for promoting cycling, such as ongoing improvement to infrastructure and advertising.

  19. Evaluation of experimental vaccines for bovine viral diarrhea in bovines, ovines and guinea pigs Evaluación de vacunas experimentales para la diarrea viral bovina en bovinos, ovinos y cobayos

    Directory of Open Access Journals (Sweden)

    F. Fernández

    2009-06-01

    Full Text Available The bovine viral diarrhea virus (BVDV infection control should be based on elimination of persistently infected animals and on immunization through vaccination, to prevent fetal infection. However, the efficacy of inactivated BVDV vaccines is variable due to its low immunogenicity. This study evaluated the humoral immune response against homologous and heterologous strains of 7 inactivated BVDV vaccines, in bovines and two experimental models (ovine and guinea pig which might be used to test candidate vaccines. Vaccines formulated with BVDV Singer, Oregon, NADL, and multivalent, induced seroconversion in the three animal models studied, reaching antibody titres higher than 2. Vaccine containing 125C -genotype 2- only induced a low antibody response in ovine, while VS-115 NCP vaccine was not immunogenic. Furthermore, bovine sera at 60 dpv presented homologous as well as heterologous antibody response, indicating a high degree of cross-reactivity among the strains studied. However, when bovine sera were tested against the Argentine field strain 00-693, they showed the lowest levels of cross-reactivity, suggesting the need of continued surveillance to identify and characterize emerging field BVDV strains. Finally, optimal correlations between bovine-ovine and bovine-guinea pig models were observed, indicating that two alternative species could replace bovines when testing the immunogenicity of BVDV candidate vaccines.El control del virus de la diarrea viral bovina (VDVB se basa en la eliminación de animales persistentemente infectados, y la inmunización de hembras para prevenir infecciones fetales. La eficiencia de estas vacunas es variable por su baja inmunogenicidad. Se evaluó la respuesta inmune humoral contra virus homólogos y heterólogos de 7 vacunas experimentales inactivadas del VDVB en bovinos y en dos modelos experimentales (ovinos y cobayos. Las vacunas conteniendo VDVB Singer, Oregon, NADL y polivalentes indujeron seroconversión en

  20. RANS simulation of a radial compressor for supercritical CO{sub 2} Brayton cycle

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Seong Gu; Cho, Seong Kuk; Lee, Jekyoung; Lee, Jeong Ik [KAIST, Daejeon (Korea, Republic of); Cha, Jae Eun [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Lee, Si Woo [Jinsol Turbo, Daejeon (Korea, Republic of)

    2016-10-15

    S-CO{sub 2} cycle has a small footprint due to the compact turbomachine and heat exchanger. It was found that the S-CO{sub 2} compressor consumes small compression work if the operating conditions approach to the critical point (7.38MPa, 31.1℃). Therefore, this reduced compression work contributes to high cycle efficiency. Due to the above mentioned advantages, the S-CO{sub 2} cycle can be applied to various heat sources such as coal power, bottoming cycle of fuel cells, and the next generation nuclear systems. To demonstrate the S-CO{sub 2} cycle performance, an integral test facility is necessary. Therefore, the joint research team of KAERI, KAIST, POSTECH designed a supercritical CO{sub 2} integral experiment loop (SCIEL). The experimental data from this loop are accumulating in various conditions, rotational speed. The design of a S-CO{sub 2} compressor operating near the critical point is one of the major technical challenges in the development of cycle components. A radial compressor geometry designed for supercritical CO{sub 2} loop was utilized for CFD analysis. The preliminary results were compared to the experimental data. In this study, the authors present a CFD approach with accurate CSV type property table. Compared results showed reasonable difference between CFD and experiment except for efficiency curve at 35,000rpm. In future works, the loss models used for the design of S-CO{sub 2} compressor will be validated, and established with CFD results.

  1. Parallel Multi-cycle LES of an Optical Pent-roof DISI Engine Under Motored Operating Conditions

    Energy Technology Data Exchange (ETDEWEB)

    Van Dam, Noah; Sjöberg, Magnus; Zeng, Wei; Som, Sibendu

    2017-10-15

    The use of Large-eddy Simulations (LES) has increased due to their ability to resolve the turbulent fluctuations of engine flows and capture the resulting cycle-to-cycle variability. One drawback of LES, however, is the requirement to run multiple engine cycles to obtain the necessary cycle statistics for full validation. The standard method to obtain the cycles by running a single simulation through many engine cycles sequentially can take a long time to complete. Recently, a new strategy has been proposed by our research group to reduce the amount of time necessary to simulate the many engine cycles by running individual engine cycle simulations in parallel. With modern large computing systems this has the potential to reduce the amount of time necessary for a full set of simulated engine cycles to finish by up to an order of magnitude. In this paper, the Parallel Perturbation Methodology (PPM) is used to simulate up to 35 engine cycles of an optically accessible, pent-roof Directinjection Spark-ignition (DISI) engine at two different motored engine operating conditions, one throttled and one un-throttled. Comparisons are made against corresponding sequential-cycle simulations to verify the similarity of results using either methodology. Mean results from the PPM approach are very similar to sequential-cycle results with less than 0.5% difference in pressure and a magnitude structure index (MSI) of 0.95. Differences in cycle-to-cycle variability (CCV) predictions are larger, but close to the statistical uncertainty in the measurement for the number of cycles simulated. PPM LES results were also compared against experimental data. Mean quantities such as pressure or mean velocities were typically matched to within 5- 10%. Pressure CCVs were under-predicted, mostly due to the lack of any perturbations in the pressure boundary conditions between cycles. Velocity CCVs for the simulations had the same average magnitude as experiments, but the experimental data showed

  2. Validation of the CORD-2 System for the Nuclear Design Calculations of the NPP Krsko Core

    International Nuclear Information System (INIS)

    Kromar, M.; Kurincic, B.

    2016-01-01

    The CORD-2 package intended for core design calculations of PWRs has be recently updated with some improved models. Since the modifications could substantially influence the obtained results, a technical validation process is required. This paper presents comparison of some calculated and measured parameters of the NPP Krsko core needed to qualify the package. Critical boron concentrations at hot full power for selected cycle burnup points and several parameters obtained during the start-up testing at the beginning of each cycle (hot zero power critical concentration, isothermal temperature coefficient and rods worth) for all 27 finished cycles of operation are considered. In addition, assembly-wise power distribution for some selected cycles is checked. Comparison has shown very good agreement of the CORD-2 calculated values with the selected measured parameter of the NPP Krsko core.(author).

  3. Marine nitrogen cycle

    Digital Repository Service at National Institute of Oceanography (India)

    Naqvi, S.W.A.

    ) such as the Marine nitrogen cycle The marine nitrogen cycle. ‘X’ and ‘Y’ are intra-cellular intermediates that do not accumulate in water column. (Source: Codispoti et al., 2001) Page 1 of 3Marine nitrogen cycle - Encyclopedia of Earth 11/20/2006http://www... and nitrous oxide budgets: Moving targets as we enter the anthropocene?, Sci. Mar., 65, 85-105, 2001. Page 2 of 3Marine nitrogen cycle - Encyclopedia of Earth 11/20/2006http://www.eoearth.org/article/Marine_nitrogen_cycle square6 Gruber, N.: The dynamics...

  4. Prevention of criticality accidents in a fuel cycle plant

    International Nuclear Information System (INIS)

    Gatti, A.M.; Canavese, S.I.; Capadona, N.M.

    1990-01-01

    This work reports the basic considerations on criticality accidents applied to an uranium dioxide fuel cycle production plant. The different fabrication stages are briefly described, with the identification of the neutronically isolated areas. Once the areas have been defined, an evaluation is made, setting up the control parameters to be used in each of them and their variation ranges; normal operation limitations based on experimental data or validating calculations, applied specifically to 5% enriched uranium, are established. Afterwards, defined parameters deviations are analyzed due to incidental conditions in order to prevent criticality accidents under normal conditions and maintenance operations. (Author) [es

  5. Znhit1 causes cell cycle arrest and down-regulates CDK6 expression

    International Nuclear Information System (INIS)

    Yang, Zhengmin; Cao, Yonghao; Zhu, Xiaoyan; Huang, Ying; Ding, Yuqiang; Liu, Xiaolong

    2009-01-01

    Cyclin-dependent kinase 6 (CDK6) is the key element of the D-type cyclin holoenzymes which has been found to function in the regulation of G1-phase of the cell cycle and is presumed to play important roles in T cell function. In this study, Znhit1, a member of a new zinc finger protein family defined by a conserved Zf-HIT domain, induced arrest in the G1-phase of the cell cycle in NIH/3T3 cells. Of the G1 cell cycle factors examined, the expression of CDK6 was found to be strongly down-regulated by Znhit1 via transcriptional repression. This effect may have correlations with the decreased acetylation level of histone H4 in the CDK6 promoter region. In addition, considering that CDK6 expression predominates in T cells, the negative regulatory role of Znhit1 in TCR-induced T cell proliferation was validated using transgenic mice. These findings identified Znhit1 as a CDK6 regulator that plays an important role in cell proliferation.

  6. Reproductive cycles in tropical intertidal gastropods are timed around tidal amplitude cycles.

    Science.gov (United States)

    Collin, Rachel; Kerr, Kecia; Contolini, Gina; Ochoa, Isis

    2017-08-01

    Reproduction in iteroparous marine organisms is often timed with abiotic cycles and may follow lunar, tidal amplitude, or daily cycles. Among intertidal marine invertebrates, decapods are well known to time larval release to coincide with large amplitude nighttime tides, which minimizes the risk of predation. Such bimonthly cycles have been reported for few other intertidal invertebrates. We documented the reproduction of 6 gastropod species from Panama to determine whether they demonstrate reproductive cycles, whether these cycles follow a 2-week cycle, and whether cycles are timed so that larval release occurs during large amplitude tides. Two of the species ( Crepidula cf. marginalis and Nerita scabricosta ) showed nonuniform reproduction, but without clear peaks in timing relative to tidal or lunar cycles. The other 4 species show clear peaks in reproduction occurring every 2 weeks. In 3 of these species ( Cerithideopsis carlifornica var. valida, Littoraria variegata , and Natica chemnitzi ), hatching occurred within 4 days of the maximum amplitude tides. Siphonaria palmata exhibit strong cycles, but reproduction occurred during the neap tides. Strong differences in the intensity of reproduction of Cerithideopsis carlifornica , and in particular, Littoraria variegata , between the larger and smaller spring tides of a lunar month indicate that these species time reproduction with the tidal amplitude cycle rather than the lunar cycle. For those species that reproduce during both the wet and dry seasons, we found that reproductive timing did not differ between seasons despite strong differences in temperature and precipitation. Overall, we found that most (4/6) species have strong reproductive cycles synchronized with the tidal amplitude cycle and that seasonal differences in abiotic factors do not alter these cycles.

  7. Sub-minute Phosphoregulation of Cell Cycle Systems during Plasmodium Gamete Formation

    Directory of Open Access Journals (Sweden)

    Brandon M. Invergo

    2017-11-01

    Full Text Available Summary: The transmission of malaria parasites to mosquitoes relies on the rapid induction of sexual reproduction upon their ingestion into a blood meal. Haploid female and male gametocytes become activated and emerge from their host cells, and the males enter the cell cycle to produce eight microgametes. The synchronized nature of gametogenesis allowed us to investigate phosphorylation signaling during its first minute in Plasmodium berghei via a high-resolution time course of the phosphoproteome. This revealed an unexpectedly broad response, with proteins related to distinct cell cycle events undergoing simultaneous phosphoregulation. We implicate several protein kinases in the process, and we validate our analyses on the plant-like calcium-dependent protein kinase 4 (CDPK4 and a homolog of serine/arginine-rich protein kinases (SRPK1. Mutants in these kinases displayed distinct phosphoproteomic disruptions, consistent with differences in their phenotypes. The results reveal the central role of protein phosphorylation in the atypical cell cycle regulation of a divergent eukaryote. : Invergo et al. measure a phosphoproteomic time course during a life cycle transition of a malarial parasite. They observed broad phosphoregulation on a sub-minute scale, including simultaneous regulation of replication- and mitosis-related proteins. Their analyses reveal conserved phosphorylation patterns, and they highlight functional roles of specific protein kinases during this process. Keywords: gametogenesis, proteomics, signal transduction, ARK2, CRK5

  8. Creeping of hysteresis cycles; Reptation des cycles d'hysteresis

    Energy Technology Data Exchange (ETDEWEB)

    Neel, L [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires; Faculte des Sciences de Grenoble, 38 (France)

    1959-07-01

    Creeping consists of a kind of progressive translation of dissymmetric ferromagnetic hysteresis cycles as a function of the order number of the cycle. It is interpreted here by means of a probable coupling field, the existence of which is connected to a statistical conception of the distribution of the elementary regions. (author) [French] La reptation consiste en une sorte de translation progressive des cycles d'hysteresis ferromagnetiques dissymetriques en fonction du numero d'ordre du cycle. L'auteur l'interprete au moyen d'un champ aleatoire de couplage dont l'existence est liee a une conception statistique de la distribution des domaines elementaires. (auteur)

  9. Standards and guidelines applicable for the validation of programmable automation systems

    International Nuclear Information System (INIS)

    Haapanen, P.; Maskuniitty, M.

    1993-02-01

    The validation of programmable automation system for an application important to safety in a nuclear power plant requires a comprehensive view about the system quality and reliability. One central point is to get assured that proper international guidelines and standards have been followed in the design, construction and maintenance of the system. The study was directed to locate international standards and guidelines which can support the validation of programmable systems and to evaluate their applicability for the validation of systems on different levels of requirement during their life cycle. The publication reviews the most important international standards (IAEA, ISO, IEC, IEEE) and their basic principles both for system and application program. Several nuclear standards, which have drawn the main attention, and some general programmable automation standards have been examined. In addition one practical automation system has been examined in order to find essential questions. Based on these studies a set of important items for the qualification have been identified

  10. Glacial cycles

    DEFF Research Database (Denmark)

    Kaufmann, R. K.; Juselius, Katarina

    We use a statistical model, the cointegrated vector autoregressive model, to assess the degree to which variations in Earth's orbit and endogenous climate dynamics can be used to simulate glacial cycles during the late Quaternary (390 kyr-present). To do so, we estimate models of varying complexity...... and compare the accuracy of their in-sample simulations. Results indicate that strong statistical associations between endogenous climate variables are not enough for statistical models to reproduce glacial cycles. Rather, changes in solar insolation associated with changes in Earth's orbit are needed...... to simulate glacial cycles accurately. Also, results suggest that non-linear 10 dynamics, threshold effects, and/or free oscillations may not play an overriding role in glacial cycles....

  11. The glutathione cycle: Glutathione metabolism beyond the γ-glutamyl cycle.

    Science.gov (United States)

    Bachhawat, Anand Kumar; Yadav, Shambhu

    2018-04-17

    Glutathione was discovered in 1888, over 125 years ago. Since then, our understanding of various functions and metabolism of this important molecule has grown over these years. But it is only now, in the last decade, that a somewhat complete picture of its metabolism has emerged. Glutathione metabolism has till now been largely depicted and understood by the γ-glutamyl cycle that was proposed in 1970. However, new findings and knowledge particularly on the transport and degradation of glutathione have revealed that many aspects of the γ-glutamyl cycle are incorrect. Despite this, an integrated critical analysis of the cycle has never been undertaken and this has led to the cycle and its errors perpetuating in the literature. This review takes a careful look at the γ-glutamyl cycle and its shortcomings and presents a "glutathione cycle" that captures the current understanding of glutathione metabolism. © 2018 IUBMB Life, 2018. © 2018 International Union of Biochemistry and Molecular Biology.

  12. Single generation cycles and delayed feedback cycles are not separate phenomena.

    Science.gov (United States)

    Pfaff, T; Brechtel, A; Drossel, B; Guill, C

    2014-12-01

    We study a simple model for generation cycles, which are oscillations with a period of one or a few generation times of the species. The model is formulated in terms of a single delay-differential equation for the population density of an adult stage, with recruitment to the adult stage depending on the intensity of competition during the juvenile phase. This model is a simplified version of a group of models proposed by Gurney and Nisbet, who were the first to distinguish between single-generation cycles and delayed-feedback cycles. According to these authors, the two oscillation types are caused by different mechanisms and have periods in different intervals, which are one to two generation times for single-generation cycles and two to four generation times for delayed-feedback cycles. By abolishing the strict coupling between the maturation time and the time delay between competition and its effect on the population dynamics, we find that single-generation cycles and delayed-feedback cycles occur in the same model version, with a gradual transition between the two as the model parameters are varied over a sufficiently large range. Furthermore, cycle periods are not bounded to lie within single octaves. This implies that a clear distinction between different types of generation cycles is not possible. Cycles of all periods and even chaos can be generated by varying the parameters that determine the time during which individuals from different cohorts compete with each other. This suggests that life-cycle features in the juvenile stage and during the transition to the adult stage are important determinants of the dynamics of density limited populations. Copyright © 2014 Elsevier Inc. All rights reserved.

  13. [Cycling in Zagreb].

    Science.gov (United States)

    Matos, Stipan; Krapac, Ladislav; Krapac, Josip

    2007-01-01

    Cycling in Zagreb, as means of urban transport inside and outside the city, has a bright past, hazy presence but a promising future. Every day, aggressive citizens who lack urban traffic culture mistreat many cyclists but also many pedestrians. Sedentary way of living, unhealthy eating habits and inadequate recreation would surely be reduced if Zagreb had a network of cycling tracks (190 cm) or lanes (80 cm). Main city roads were constructed at the beginning of the 20th century. Today, the lack of cycling tracks is particularly evident in terms of missing connections between northern and southern parts of the city. Transportation of bikes in public vehicles, parking of bikes as well as cycling along the foot of the mountains Medvednica and Zumberacko gorje is not adequately organized. Better organization is necessary not only because of the present young generation but also because of the young who will shortly become citizens of the EU, where cycling is enormously popular. Cycling tourism is not known in Zagreb, partly due to inadequate roads. The surroundings of Zagreb are more suitable for cycling tourism and attractive brochures and tourist guides offer information to tourists on bikes. Professional, acrobatic and sports cycling do not have a tradition in Zagreb and in Croatia. The same holds true for recreational cycling and indoor exercise cycling. The authors discuss the impact of popularization of cycling using print and electronic media. The role of district and local self-government in the construction and improvement of traffic roads in Zagreb is very important. It is also significant for the implementation of legal regulations that must be obeyed by all traffic participants in order to protect cyclists, the most vulnerable group of traffic participants besides passengers. Multidisciplinary action of all benevolent experts would surely increase safety and pleasure of cycling in the city and its surroundings. This would also help reduce daily stress and

  14. Verification and Validation of Digitally Upgraded Control Rooms

    International Nuclear Information System (INIS)

    Boring, Ronald; Lau, Nathan

    2015-01-01

    As nuclear power plants undertake main control room modernization, a challenge is the lack of a clearly defined human factors process to follow. Verification and validation (V&V) as applied in the nuclear power community has tended to involve efforts such as integrated system validation, which comes at the tail end of the design stage. To fill in guidance gaps and create a step-by-step process for control room modernization, we have developed the Guideline for Operational Nuclear Usability and Knowledge Elicitation (GONUKE). This approach builds on best practices in the software industry, which prescribe an iterative user-centered approach featuring multiple cycles of design and evaluation. Nuclear regulatory guidance for control room design emphasizes summative evaluation - which occurs after the design is complete. In the GONUKE approach, evaluation is also performed at the formative stage of design - early in the design cycle using mockups and prototypes for evaluation. The evaluation may involve expert review (e.g., software heuristic evaluation at the formative stage and design verification against human factors standards like NUREG-0700 at the summative stage). The evaluation may also involve user testing (e.g., usability testing at the formative stage and integrated system validation at the summative stage). An additional, often overlooked component of evaluation is knowledge elicitation, which captures operator insights into the system. In this report we outline these evaluation types across design phases that support the overall modernization process. The objective is to provide industry-suitable guidance for steps to be taken in support of the design and evaluation of a new human-machine interface (HMI) in the control room. We suggest the value of early-stage V&V and highlight how this early-stage V&V can help improve the design process for control room modernization. We argue that there is a need to overcome two shortcomings of V&V in current practice

  15. Verification and Validation of Digitally Upgraded Control Rooms

    Energy Technology Data Exchange (ETDEWEB)

    Boring, Ronald [Idaho National Lab. (INL), Idaho Falls, ID (United States); Lau, Nathan [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-09-01

    As nuclear power plants undertake main control room modernization, a challenge is the lack of a clearly defined human factors process to follow. Verification and validation (V&V) as applied in the nuclear power community has tended to involve efforts such as integrated system validation, which comes at the tail end of the design stage. To fill in guidance gaps and create a step-by-step process for control room modernization, we have developed the Guideline for Operational Nuclear Usability and Knowledge Elicitation (GONUKE). This approach builds on best practices in the software industry, which prescribe an iterative user-centered approach featuring multiple cycles of design and evaluation. Nuclear regulatory guidance for control room design emphasizes summative evaluation—which occurs after the design is complete. In the GONUKE approach, evaluation is also performed at the formative stage of design—early in the design cycle using mockups and prototypes for evaluation. The evaluation may involve expert review (e.g., software heuristic evaluation at the formative stage and design verification against human factors standards like NUREG-0700 at the summative stage). The evaluation may also involve user testing (e.g., usability testing at the formative stage and integrated system validation at the summative stage). An additional, often overlooked component of evaluation is knowledge elicitation, which captures operator insights into the system. In this report we outline these evaluation types across design phases that support the overall modernization process. The objective is to provide industry-suitable guidance for steps to be taken in support of the design and evaluation of a new human-machine interface (HMI) in the control room. We suggest the value of early-stage V&V and highlight how this early-stage V&V can help improve the design process for control room modernization. We argue that there is a need to overcome two shortcomings of V&V in current practice

  16. Optimization and experimental validation of a thermal cycle that maximizes entropy coefficient fisher identifiability for lithium iron phosphate cells

    Science.gov (United States)

    Mendoza, Sergio; Rothenberger, Michael; Hake, Alison; Fathy, Hosam

    2016-03-01

    This article presents a framework for optimizing the thermal cycle to estimate a battery cell's entropy coefficient at 20% state of charge (SOC). Our goal is to maximize Fisher identifiability: a measure of the accuracy with which a parameter can be estimated. Existing protocols in the literature for estimating entropy coefficients demand excessive laboratory time. Identifiability optimization makes it possible to achieve comparable accuracy levels in a fraction of the time. This article demonstrates this result for a set of lithium iron phosphate (LFP) cells. We conduct a 24-h experiment to obtain benchmark measurements of their entropy coefficients. We optimize a thermal cycle to maximize parameter identifiability for these cells. This optimization proceeds with respect to the coefficients of a Fourier discretization of this thermal cycle. Finally, we compare the estimated parameters using (i) the benchmark test, (ii) the optimized protocol, and (iii) a 15-h test from the literature (by Forgez et al.). The results are encouraging for two reasons. First, they confirm the simulation-based prediction that the optimized experiment can produce accurate parameter estimates in 2 h, compared to 15-24. Second, the optimized experiment also estimates a thermal time constant representing the effects of thermal capacitance and convection heat transfer.

  17. Dynamic simulation of a sorption machine : application to a two-stage waterfall cycle; Simulation dynamique d'une machine a adsorption : application a un cycle cascade bi-etage

    Energy Technology Data Exchange (ETDEWEB)

    Lachance, D.; Bernier, M. [Ecole Polytechnique, Montreal, PQ (Canada). Dept. de Genie Mecanique; Castaing-Lasvignottes, J.; Meunier, F. [Laboratoire du Froid, CNAM, Paris (France)

    2002-07-01

    Trithermal sorption machines are an alternative solution to replace conventional refrigeration and air conditioning systems. This paper completed and followed other work concerning the study of the performance of a two-stage waterfall cycle, coupling a water/zeolite adsorption machine to a water/lithium bromide absorption machine. The objective of the coupling was to increase the global coefficient of performance of the installation. A dynamic model of the behaviour of the water/zeolite adsorption machine simple effect was described and validated using experimental data. The model was then adapted to the double effect cycle heat recovery in order to perform its energy analysis. The originality of this system stems from its functioning at relatively high condensation and regeneration temperatures of 100 Celsius and 300 Celsius respectively, leading to a high compression rate of 100 to 1. 6 refs., 12 figs.

  18. Model training across multiple breeding cycles significantly improves genomic prediction accuracy in rye (Secale cereale L.).

    Science.gov (United States)

    Auinger, Hans-Jürgen; Schönleben, Manfred; Lehermeier, Christina; Schmidt, Malthe; Korzun, Viktor; Geiger, Hartwig H; Piepho, Hans-Peter; Gordillo, Andres; Wilde, Peer; Bauer, Eva; Schön, Chris-Carolin

    2016-11-01

    Genomic prediction accuracy can be significantly increased by model calibration across multiple breeding cycles as long as selection cycles are connected by common ancestors. In hybrid rye breeding, application of genome-based prediction is expected to increase selection gain because of long selection cycles in population improvement and development of hybrid components. Essentially two prediction scenarios arise: (1) prediction of the genetic value of lines from the same breeding cycle in which model training is performed and (2) prediction of lines from subsequent cycles. It is the latter from which a reduction in cycle length and consequently the strongest impact on selection gain is expected. We empirically investigated genome-based prediction of grain yield, plant height and thousand kernel weight within and across four selection cycles of a hybrid rye breeding program. Prediction performance was assessed using genomic and pedigree-based best linear unbiased prediction (GBLUP and PBLUP). A total of 1040 S 2 lines were genotyped with 16 k SNPs and each year testcrosses of 260 S 2 lines were phenotyped in seven or eight locations. The performance gap between GBLUP and PBLUP increased significantly for all traits when model calibration was performed on aggregated data from several cycles. Prediction accuracies obtained from cross-validation were in the order of 0.70 for all traits when data from all cycles (N CS  = 832) were used for model training and exceeded within-cycle accuracies in all cases. As long as selection cycles are connected by a sufficient number of common ancestors and prediction accuracy has not reached a plateau when increasing sample size, aggregating data from several preceding cycles is recommended for predicting genetic values in subsequent cycles despite decreasing relatedness over time.

  19. Optimal number of tests to achieve and validate product reliability

    International Nuclear Information System (INIS)

    Ahmed, Hussam; Chateauneuf, Alaa

    2014-01-01

    The reliability validation of engineering products and systems is mandatory for choosing the best cost-effective design among a series of alternatives. Decisions at early design stages have a large effect on the overall life cycle performance and cost of products. In this paper, an optimization-based formulation is proposed by coupling the costs of product design and validation testing, in order to ensure the product reliability with the minimum number of tests. This formulation addresses the question about the number of tests to be specified through reliability demonstration necessary to validate the product under appropriate confidence level. The proposed formulation takes into account the product cost, the failure cost and the testing cost. The optimization problem can be considered as a decision making system according to the hierarchy of structural reliability measures. The numerical examples show the interest of coupling design and testing parameters. - Highlights: • Coupled formulation for design and testing costs, with lifetime degradation. • Cost-effective testing optimization to achieve reliability target. • Solution procedure for nested aleatoric and epistemic variable spaces

  20. Cycle to Cycle Variation Study in a Dual Fuel Operated Engine

    KAUST Repository

    Pasunurthi, Shyamsundar

    2017-03-28

    The standard capability of engine experimental studies is that ensemble averaged quantities like in-cylinder pressure from multiple cycles and emissions are reported and the cycle to cycle variation (CCV) of indicated mean effective pressure (IMEP) is captured from many consecutive combustion cycles for each test condition. However, obtaining 3D spatial distribution of all the relevant quantities such as fuel-air mixing, temperature, turbulence levels and emissions from such experiments is a challenging task. Computational Fluid Dynamics (CFD) simulations of engine flow and combustion can be used effectively to visualize such 3D spatial distributions. A dual fuel engine is considered in the current study, with manifold injected natural gas (NG) and direct injected diesel pilot for ignition. Multiple engine cycles in 3D are simulated in series like in the experiments to investigate the potential of high fidelity RANS simulations coupled with detailed chemistry, to accurately predict the CCV. Cycle to cycle variation (CCV) is expected to be due to variabilities in operating and boundary conditions, in-cylinder stratification of diesel and natural gas fuels, variation in in-cylinder turbulence levels and velocity flow-fields. In a previous publication by the authors [1], variabilities in operating and boundary conditions are incorporated into several closed cycle simulations performed in parallel. Stochastic variations/stratifications of fuel-air mixture, turbulence levels, temperature and internal combustion residuals cannot be considered in such closed cycle simulations. In this study, open cycle simulations with port injection of natural gas predicted the combined effect of the stratifications on the CCV of in-cylinder pressure. The predicted Coefficient of Variation (COV) of cylinder pressure is improved compared to the one captured by closed cycle simulations in parallel.

  1. Internal cycle modeling and environmental assessment of multiple cycle consumer products

    International Nuclear Information System (INIS)

    Tsiliyannis, C.A.

    2012-01-01

    Highlights: ► Dynamic flow models are presented for remanufactured, reused or recycled products. ► Early loss and stochastic return are included for fast and slow cycling products. ► The reuse-to-input flow ratio (Internal Cycle Factor, ICF) is determined. ► The cycle rate, which is increasing with the ICF, monitors eco-performance. ► Early internal cycle losses diminish the ICF, the cycle rate and performance. - Abstract: Dynamic annual flow models incorporating consumer discard and usage loss and featuring deterministic and stochastic end-of-cycle (EOC) return by the consumer are developed for reused or remanufactured products (multiple cycle products, MCPs), including fast and slow cycling, short and long-lived products. It is shown that internal flows (reuse and overall consumption) increase proportionally to the dimensionless internal cycle factor (ICF) which is related to environmental impact reduction factors. The combined reuse/recycle (or cycle) rate is shown capable for shortcut, albeit effective, monitoring of environmental performance in terms of waste production, virgin material extraction and manufacturing impacts of all MCPs, a task, which physical variables (lifetime, cycling frequency, mean or total number of return trips) and conventional rates, via which environmental policy has been officially implemented (e.g. recycling rate) cannot accomplish. The cycle rate is shown to be an increasing (hyperbolic) function of ICF. The impact of the stochastic EOC return characteristics on total reuse and consumption flows, as well as on eco-performance, is assessed: symmetric EOC return has a small, positive effect on performance compared to deterministic, while early shifted EOC return is more beneficial. In order to be efficient, environmental policy should set higher minimum reuse targets for higher trippage MCPs. The results may serve for monitoring, flow accounting and comparative eco-assessment of MCPs. They may be useful in identifying

  2. Advanced training simulator models. Implementation and validation

    International Nuclear Information System (INIS)

    Borkowsky, Jeffrey; Judd, Jerry; Belblidia, Lotfi; O'farrell, David; Andersen, Peter

    2008-01-01

    Modern training simulators are required to replicate plant data for both thermal-hydraulic and neutronic response. Replication is required such that reactivity manipulation on the simulator properly trains the operator for reactivity manipulation at the plant. This paper discusses advanced models which perform this function in real-time using the coupled code system THOR/S3R. This code system models the all fluids systems in detail using an advanced, two-phase thermal-hydraulic a model. The nuclear core is modeled using an advanced, three-dimensional nodal method and also by using cycle-specific nuclear data. These models are configured to run interactively from a graphical instructor station or handware operation panels. The simulator models are theoretically rigorous and are expected to replicate the physics of the plant. However, to verify replication, the models must be independently assessed. Plant data is the preferred validation method, but plant data is often not available for many important training scenarios. In the absence of data, validation may be obtained by slower-than-real-time transient analysis. This analysis can be performed by coupling a safety analysis code and a core design code. Such a coupling exists between the codes RELAP5 and SIMULATE-3K (S3K). RELAP5/S3K is used to validate the real-time model for several postulated plant events. (author)

  3. An IMS Station life cycle from a sustainment point of view

    Science.gov (United States)

    Brely, Natalie; Gautier, Jean-Pierre; Foster, Daniel

    2014-05-01

    The International Monitoring System (IMS) is to consist of 321 monitoring facilities, composed of four different technologies with a variety of designs and equipment types, deployed in a range of environments around the globe. The International Monitoring System is conceived to operate in perpetuity through maintenance, replacement and recapitalization of IMS facilities' infrastructure and equipment when the end of service life is reached [CTBT/PTS/INF.1163]. Life Cycle techniques and modellization are being used by the PTS to plan and forecast life cycle sustainment requirements of IMS facilities. Through historical data analysis, Engineering inputs and Feedback from experienced Station Operators, the PTS currently works towards increasing the level of confidence on these forecasts and sustainment requirements planning. Continued validation, feedback and improvement of source data from scientific community and experienced users is sought and essential in order to ensure limited effect on data availability and optimal costs (human and financial).

  4. Cycle to Cycle Variation Study in a Dual Fuel Operated Engine

    KAUST Repository

    Pasunurthi, Shyamsundar; Jupudi, Ravichandra; Wijeyakulasuriya, Sameera; Gubba, Sreenivasa Rao; Im, Hong G.; Jaasim, Mohammed; Primus, Roy; Klingbeil, Adam; Finney, Charles

    2017-01-01

    The standard capability of engine experimental studies is that ensemble averaged quantities like in-cylinder pressure from multiple cycles and emissions are reported and the cycle to cycle variation (CCV) of indicated mean effective pressure (IMEP

  5. Verification and Validation Issues in Systems of Systems

    Directory of Open Access Journals (Sweden)

    Eric Honour

    2013-11-01

    Full Text Available The cutting edge in systems development today is in the area of "systems of systems" (SoS large networks of inter-related systems that are developed and managed separately, but that also perform collective activities. Such large systems typically involve constituent systems operating with different life cycles, often with uncoordinated evolution. The result is an ever-changing SoS in which adaptation and evolution replace the older engineering paradigm of "development". This short paper presents key thoughts about verification and validation in this environment. Classic verification and validation methods rely on having (a a basis of proof, in requirements and in operational scenarios, and (b a known system configuration to be proven. However, with constant SoS evolution, management of both requirements and system configurations are problematic. Often, it is impossible to maintain a valid set of requirements for the SoS due to the ongoing changes in the constituent systems. Frequently, it is even difficult to maintain a vision of the SoS operational use as users find new ways to adapt the SoS. These features of the SoS result in significant challenges for system proof. In addition to discussing the issues, the paper also indicates some of the solutions that are currently used to prove the SoS.

  6. A New Multiaxial High-Cycle Fatigue Criterion Based on the Critical Plane for Ductile and Brittle Materials

    Science.gov (United States)

    Wang, Cong; Shang, De-Guang; Wang, Xiao-Wei

    2015-02-01

    An improved high-cycle multiaxial fatigue criterion based on the critical plane was proposed in this paper. The critical plane was defined as the plane of maximum shear stress (MSS) in the proposed multiaxial fatigue criterion, which is different from the traditional critical plane based on the MSS amplitude. The proposed criterion was extended as a fatigue life prediction model that can be applicable for ductile and brittle materials. The fatigue life prediction model based on the proposed high-cycle multiaxial fatigue criterion was validated with experimental results obtained from the test of 7075-T651 aluminum alloy and some references.

  7. Validation and assessment of uncertainty of chemical tests as a tool for the reliability analysis of wastewater IPEN

    International Nuclear Information System (INIS)

    Silva, Renan A.; Martins, Elaine A.J.; Furusawa, Helio A.

    2011-01-01

    The validation of analytical methods has become an indispensable tool for the analysis in chemical laboratories, including being required for such accreditation. However, even if a laboratory using validated methods of analysis there is the possibility that these methods generate results discrepant with reality by making necessary the addition of a quantitative attribute (a value) which indicates the degree of certainty the extent or the analytical method used. This measure assigned to the result of measurement is called measurement uncertainty. We estimate this uncertainty with a level of confidence both direction, an analytical result has limited significance if not carried out proper assessment of its uncertainty. One of the activities of this work was to elaborate a program to help the validation and evaluation of uncertainty in chemical analysis. The program was developed with Visual Basic programming language and method of evaluation of uncertainty introduced the following concepts based on the GUM (Guide to the Expression of Uncertainty in Measurement). This evaluation program uncertainty measurement will be applied to chemical analysis in support of the characterization of the Nuclear Fuel Cycle developed by IPEN and the study of organic substances in wastewater associated with professional activities of the Institute. In the first case, primarily for the determination of total uranium and the second case for substances that were generated by human activities and that are contained in resolution 357/2005. As strategy for development of this work was considered the PDCA cycle to improve the efficiency of each step and minimize errors while performing the experimental part. The program should be validated to meet requirements of standards such as, for example, the standard ISO/IEC 17025. The application, it is projected to use in other analytical procedures of both the Nuclear Fuel Cycle and in the control program and chemical waste management of IPEN

  8. Validation and assessment of uncertainty of chemical tests as a tool for the reliability analysis of wastewater IPEN

    Energy Technology Data Exchange (ETDEWEB)

    Silva, Renan A.; Martins, Elaine A.J.; Furusawa, Helio A., E-mail: elaine@ipen.br, E-mail: helioaf@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2011-07-01

    The validation of analytical methods has become an indispensable tool for the analysis in chemical laboratories, including being required for such accreditation. However, even if a laboratory using validated methods of analysis there is the possibility that these methods generate results discrepant with reality by making necessary the addition of a quantitative attribute (a value) which indicates the degree of certainty the extent or the analytical method used. This measure assigned to the result of measurement is called measurement uncertainty. We estimate this uncertainty with a level of confidence both direction, an analytical result has limited significance if not carried out proper assessment of its uncertainty. One of the activities of this work was to elaborate a program to help the validation and evaluation of uncertainty in chemical analysis. The program was developed with Visual Basic programming language and method of evaluation of uncertainty introduced the following concepts based on the GUM (Guide to the Expression of Uncertainty in Measurement). This evaluation program uncertainty measurement will be applied to chemical analysis in support of the characterization of the Nuclear Fuel Cycle developed by IPEN and the study of organic substances in wastewater associated with professional activities of the Institute. In the first case, primarily for the determination of total uranium and the second case for substances that were generated by human activities and that are contained in resolution 357/2005. As strategy for development of this work was considered the PDCA cycle to improve the efficiency of each step and minimize errors while performing the experimental part. The program should be validated to meet requirements of standards such as, for example, the standard ISO/IEC 17025. The application, it is projected to use in other analytical procedures of both the Nuclear Fuel Cycle and in the control program and chemical waste management of IPEN

  9. The Baltic Sea Experiment (BALTEX): A European contribution to the investigation of the energy and water cycle over a large drainage basin

    DEFF Research Database (Denmark)

    Raschke, E.; Meywerk, J.; Warrach, K.

    2001-01-01

    The Baltic Sea Experiment (BALTEX) is one of the five continental-scale experiments of the Global Energy and Water Cycle Experiment (GEWEX). More than 50 research groups from 14 European countries are participating in this project to measure and model the energy and water cycle over the large...... drainage basin of the Baltic Sea in northern Europe. BALTEX aims to provide a better understanding of the processes of the climate system and to improve and to validate the water cycle in regional numerical models for weather forecasting and climate studies. A major effort is undertaken to couple...

  10. The Hamburg oceanic carbon cycle circulation model. Cycle 1

    International Nuclear Information System (INIS)

    Maier-Reimer, E.; Heinze, C.

    1992-02-01

    The carbon cycle model calculates the prognostic fields of oceanic geochemical carbon cycle tracers making use of a 'frozen' velocity field provided by a run of the LSG oceanic circulation model (see the corresponding manual, LSG=Large Scale Geostrophic). The carbon cycle model includes a crude approximation of interactions between sediment and bottom layer water. A simple (meridionally diffusive) one layer atmosphere model allows to calculate the CO 2 airborne fraction resulting from the oceanic biogeochemical interactions. (orig.)

  11. Future fuel cycles

    International Nuclear Information System (INIS)

    Archinoff, G.H.

    1980-01-01

    A fuel cycle must offer both financial and resource savings if it is to be considered for introduction into Ontario's nuclear system. The most promising alternative CANDU fuel cycles are examined in the context of both of these factors over a wide range of installed capacity growth rates and economic assumptions, in order to determine which fuel cycle, or cycles, should be introduced, and when. It is concluded that the optimum path for the long term begins with the prompt introduction of the low-enriched-uranium fuel cycle. For a wide range of conditions, this cycle remains the optimum throughout the very long term. Conditions of rapid nuclear growth and very high uranium price escalation rates warrant the supersedure of the low-enriched-uranium cycle by either a plutonium-topped thorium cycle or plutonium recycle, beginning between 2010 and 2025. It is also found that the uranium resource position is sound in terms of both known resources and production capability. Moreover, introduction of the low-enriched-uranium fuel cycle and 1250 MWe reactor units will assure the economic viability of nuclear power until at least 2020, even if uranium prices increase at a rate of 3.5% above inflation. The interrelationship between these two conclusions lies in the tremendous incentive for exploration which will occur if the real uranium price escalation rate is high. From a competitive viewpoint, nuclear power can withstand increases in the price of uranium. However, such increases will likely further expand the resource base, making nuclear an even more reliable energy source. (auth)

  12. ELECTRO-THERMAL AND MECHANICAL VALIDATION EXPERIMENT ON THE LHC MAIN BUSBAR SPLICE CONSOLIDATION

    CERN Document Server

    Willering, GP; Bourcey, N; Bottura, L; Charrondiere, M; Cerqueira Bastos, M; Deferne, G; Dib, G; Giloux, Chr; Grand-Clement, L; Heck, S; Hudson, G; Kudryavtsev, D; Perret, P; Pozzobon, M; Prin, H; Scheuerlein, Chr; Rijllart, A; Triquet, S; Verweij, AP

    2012-01-01

    To eliminate the risk of thermal runaways in LHC interconnections a consolidation by placing shunts on the main bus bar interconnections is proposed by the Task Force Splices Consolidation. To validate the design two special SSS magnet spares are placed on a test bench in SM-18 to measure the interconnection in between with conditions as close as possible to the LHC conditions. Two dipole interconnections are instrumented and prepared with worst-case-conditions to study the thermo-electric stability limits. Two quadrupole interconnections are instrumented and prepared for studying the effect of current cycling on the mechanical stability of the consolidation design. All 4 shunted interconnections showed very stable behaviour, well beyond the LHC design current cycle.

  13. Life Cycle Management

    DEFF Research Database (Denmark)

    Bey, Niki

    2018-01-01

    This chapter gives an overview of Life Cycle Management (LCM)—a discipline that deals with the managerial tasks related to practicing sustainable development in an organisation . Just as Life Cycle Assessment, LCM advocates the life cycle perspective , and it applies this perspective in decision...

  14. BWROPT: A multi-cycle BWR fuel cycle optimization code

    Energy Technology Data Exchange (ETDEWEB)

    Ottinger, Keith E.; Maldonado, G. Ivan, E-mail: Ivan.Maldonado@utk.edu

    2015-09-15

    Highlights: • A multi-cycle BWR fuel cycle optimization algorithm is presented. • New fuel inventory and core loading pattern determination. • The parallel simulated annealing algorithm was used for the optimization. • Variable sampling probabilities were compared to constant sampling probabilities. - Abstract: A new computer code for performing BWR in-core and out-of-core fuel cycle optimization for multiple cycles simultaneously has been developed. Parallel simulated annealing (PSA) is used to optimize the new fuel inventory and placement of new and reload fuel for each cycle considered. Several algorithm improvements were implemented and evaluated. The most significant of these are variable sampling probabilities and sampling new fuel types from an ordered array. A heuristic control rod pattern (CRP) search algorithm was also implemented, which is useful for single CRP determinations, however, this feature requires significant computational resources and is currently not practical for use in a full multi-cycle optimization. The PSA algorithm was demonstrated to be capable of significant objective function reduction and finding candidate loading patterns without constraint violations. The use of variable sampling probabilities was shown to reduce runtime while producing better results compared to using constant sampling probabilities. Sampling new fuel types from an ordered array was shown to have a mixed effect compared to random new fuel type sampling, whereby using both random and ordered sampling produced better results but required longer runtimes.

  15. LOS CONOCIMIENTOS EXPERIMENTALES EN LAS PRÁCTICAS EDUCATIVAS DE LOS PARALELOS CON TIEMPO EXTENDIDO BAJO EL PROGRAMA MÁS EDUCACIÓN: UN ESTUDO DE CASO EN DUQUE DE CAXIAS/RJ

    Directory of Open Access Journals (Sweden)

    Sheila Cristina Monteiro Matos

    2012-07-01

    Full Text Available Este estudio tuvo como objetivo analizar cómo se está desarrollando el conocimiento experimental en las prácticas educativas de la Escuela Municipal Visconde de Itaboraí, en el municipio de Duque de Caxias, desde la aplicación del Programa “Más Educación/Más Escuela”. Para ello, se utilizó el método dialéctico impartido por Frigotto, teniendo como método de análisis el estudio de caso. El trabajo de campo se desarrolló a través de entrevistas, observaciones y la investigación de registros. El análisis de datos se realizó mediante análisis de contenido según Bardin. El estudio de la práctica educativa y del conocimiento experimental tuve como referencia las enseñanzas de Tardif sobre el conocimiento docente. En síntesis, podemos decir que los conocimientos experimentales en las prácticas educativas promueven la formación integral, proporcionando un mejor rendimiento académico de los estudiantes, aunque tímidamente, pues la articulación de las materias entre los turnos es un obstáculo importante para la efectividad de las prácticas educativas.

  16. Computational Modelling of Patella Femoral Kinematics During Gait Cycle and Experimental Validation

    Science.gov (United States)

    Maiti, Raman

    2016-06-01

    The effect of loading and boundary conditions on patellar mechanics is significant due to the complications arising in patella femoral joints during total knee replacements. To understand the patellar mechanics with respect to loading and motion, a computational model representing the patella femoral joint was developed and validated against experimental results. The computational model was created in IDEAS NX and simulated in MSC ADAMS/VIEW software. The results obtained in the form of internal external rotations and anterior posterior displacements for a new and experimentally simulated specimen for patella femoral joint under standard gait condition were compared with experimental measurements performed on the Leeds ProSim knee simulator. A good overall agreement between the computational prediction and the experimental data was obtained for patella femoral kinematics. Good agreement between the model and the past studies was observed when the ligament load was removed and the medial lateral displacement was constrained. The model is sensitive to ±5 % change in kinematics, frictional, force and stiffness coefficients and insensitive to time step.

  17. Ultimate refrigerating conditions, behavior turning and a thermodynamic analysis for absorption–compression hybrid refrigeration cycle

    International Nuclear Information System (INIS)

    Zheng Danxing; Meng Xuelin

    2012-01-01

    Highlights: ► Two novel fundamental concepts of the absorption refrigeration cycle were proposed. ► The interaction mechanism of compressor pressure increasing with other key-parameters was investigated. ► A set of optimal operating condition of hybrid refrigeration cycle was found. ► A simulation and investigation for R134a-DMF hybrid refrigeration cycle was performed. - Abstract: The absorption–compression hybrid refrigeration cycle has been considered as an effective approach to reduce the mechanical work consumption by using low-grade heat, such as solar energy. This work aims at studying the thermodynamic mechanism of the hybrid refrigeration cycle. Two fundamental concepts have been proposed, which are the ultimate refrigerating temperature (or the ultimate temperature lift) and the behavior turning. On the basis of that, the interaction mechanism of compressor pressure increasing with other key-parameters and the impact of compressor pressure increasing on the cycle performance have been investigated. The key-parameters include the concentration difference, the circulation ratio of working fluid, etc. The work points out that the hybrid refrigeration cycle performance varies with the change of compressor outlet pressure and depends on which one achieves dominance in the hybrid refrigeration cycle, the absorption sub-system or the compression sub-system. The behavior turning point during parameters changing corresponds to a maximum value of the heat powered coefficient of performance. In this case, the hybrid refrigeration cycle performance is optimal because the low-grade heat utilization is the most effective. In addition, to validate the theoretical analysis, a solar hybrid refrigeration cycle with R134a–DMF as working pair was simulated. The Peng–Robinson equation of state was adopted to calculate thermophysical properties when the reliability assessment of the prediction models on the available literature data of R134a–DMF system had been

  18. Measuring brain activity cycling (BAC) in long term EEG monitoring of preterm babies

    International Nuclear Information System (INIS)

    Stevenson, Nathan J; Palmu, Kirsi; Wikström, Sverre; Hellström-Westas, Lena; Vanhatalo, Sampsa

    2014-01-01

    Measuring fluctuation of vigilance states in early preterm infants undergoing long term intensive care holds promise for monitoring their neurological well-being. There is currently, however, neither objective nor quantitative methods available for this purpose in a research or clinical environment. The aim of this proof-of-concept study was, therefore, to develop quantitative measures of the fluctuation in vigilance states or brain activity cycling (BAC) in early preterm infants. The proposed measures of BAC were summary statistics computed on a frequency domain representation of the proportional duration of spontaneous activity transients (SAT%) calculated from electroencephalograph (EEG) recordings. Eighteen combinations of three statistics and six frequency domain representations were compared to a visual interpretation of cycling in the SAT% signal. Three high performing measures (band energy/periodogram: R = 0.809, relative band energy/nonstationary frequency marginal: R = 0.711, g-statistic/nonstationary frequency marginal: R = 0.638) were then compared to a grading of sleep wake cycling based on the visual interpretation of the amplitude-integrated EEG trend. These measures of BAC are conceptually straightforward, correlate well with the visual scores of BAC and sleep wake cycling, are robust enough to cope with the technically compromised monitoring data available in intensive care units, and are recommended for further validation in prospective studies. (paper)

  19. Determination of equilibrium fuel composition for fast reactor in closed fuel cycle

    Directory of Open Access Journals (Sweden)

    Ternovykha Mikhail

    2017-01-01

    Full Text Available Technique of evaluation of multiplying and reactivity characteristics of fast reactor operating in the mode of multiple refueling is presented. We describe the calculation model of the vertical section of the reactor. Calculation validations of the possibility of correct application of methods and models are given. Results on the isotopic composition, mass feed, and changes in the reactivity of the reactor in closed fuel cycle are obtained. Recommendations for choosing perspective fuel compositions for further research are proposed.

  20. Sulfur cycle

    Digital Repository Service at National Institute of Oceanography (India)

    LokaBharathi, P.A.

    Microbes, especially bacteria, play an important role in oxidative and reductive cycle of sulfur. The oxidative part of the cycle is mediated by photosynthetic bacteria in the presence of light energy and chemosynthetic forms in the absence of light...

  1. Harmonisation of criticality assessments of packages for the transport of fissile nuclear fuel cycle materials

    International Nuclear Information System (INIS)

    Farrington, L.

    2004-01-01

    The transport of fissile nuclear fuel cycle materials is an international business, and for international shipments the regulations require a package to be certified by each country through or into which the consignment is to be transported. This raises a number of harmonisation issues, which have an important bearing on transport activities. National authorities carry out independent reviews of the criticality safety of packages containing fissile materials but the underlying assumptions used in the calculations can differ, and the outcome is that implementation of the regulations is not uniform. A single design may require multiple criticality analyses to obtain base approval and foreign validations. When several competent authorities are involved, the approval and validation process of package design can often become a time-consuming, expensive and unpredictably lengthy process that can have a significant detrimental effect upon the businesses involved. The characteristics of the fissile nuclear fuel cycle materials transported by the various countries have much in common and so have the designs of the packages to contain them. A greater degree of standardisation should allow criticality safety to be assessed consistently and efficiently with benefits for the nuclear transport industry and the regulatory bodies. (author)

  2. Harmonisation of criticality assessments of packages for the transport of fissile nuclear fuel cycle materials

    International Nuclear Information System (INIS)

    Farrington, L.

    2004-01-01

    The transport of fissile nuclear fuel cycle materials is an international business and for international shipments the regulations require a package to be certified by each country through or into which the consignment is to be transported. This raises a number of harmonisation issues, which have an important bearing on transport activities. National authorities carry out independent reviews of criticality safety of packages containing fissile materials but the underlying assumptions used in the calculations can differ, and the outcome is that implementation of the regulations is not uniform. A single design may require multiple criticality analyses to obtain base approval and foreign validations. When several Competent Authorities are involved, the approval and validation process of package design can often become time consuming, expensive and an unpredictably lengthy process that can have a significant detrimental effect upon the businesses involved. The characteristics of the fissile nuclear fuel cycle materials transported by the various countries have much in common and so have the designs of the packages to contain them. A greater degree of standardisation should allow criticality safety to be assessed consistently and efficiently with benefits for the nuclear transport industry and the regulatory bodies

  3. Fast Reactor Fuel Cycle Cost Estimates for Advanced Fuel Cycle Studies

    International Nuclear Information System (INIS)

    Harrison, Thomas

    2013-01-01

    Presentation Outline: • Why Do I Need a Cost Basis?; • History of the Advanced Fuel Cycle Cost Basis; • Description of the Cost Basis; • Current Work; • Fast Reactor Fuel Cycle Applications; • Sample Fuel Cycle Cost Estimate Analysis; • Future Work

  4. Control system options and strategies for supercritical CO2 cycles.

    Energy Technology Data Exchange (ETDEWEB)

    Moisseytsev, A.; Kulesza, K. P.; Sienicki, J. J.; Nuclear Engineering Division; Oregon State Univ.

    2009-06-18

    well as the benefits in expanding the range over which individual control mechanisms are effective for cycle control. However, a combination of mechanisms is still required for control of the S-CO{sub 2} Brayton Cycle between 0 and 100 % load. An effort is underway to partially validate the Argonne models and codes by means of comparison with data from tests carried out using the small-scale Sandia Brayton Loop (SBL) recuperated gas closed Brayton cycle facility. The centrifugal compressor model has been compared with data from the SBL operating with nitrogen gas and good agreement is obtained between calculations and the measured data for the compressor outlet pressure versus flow rate, although it is necessary to assume values for certain model parameters which require information about the configuration or dimensions of the compressor components that is unavailable. Unfortunately, the compressor efficiency cannot be compared with experiment data due to the lack of outlet temperature data. A radial inflow turbine model has been developed to enable further comparison of calculations with data from the SBL which incorporates both a radial inflow turbine as well as a radial compressor. Preliminary calculations of pressure ratio and efficiency versus flow rate have been carried out using the radial inflow turbine model.

  5. Control system options and strategies for supercritical CO2 cycles

    International Nuclear Information System (INIS)

    Moisseytsev, A.; Kulesza, K.P.; Sienicki, J.J.

    2009-01-01

    over which individual control mechanisms are effective for cycle control. However, a combination of mechanisms is still required for control of the S-CO 2 Brayton Cycle between 0 and 100 % load. An effort is underway to partially validate the Argonne models and codes by means of comparison with data from tests carried out using the small-scale Sandia Brayton Loop (SBL) recuperated gas closed Brayton cycle facility. The centrifugal compressor model has been compared with data from the SBL operating with nitrogen gas and good agreement is obtained between calculations and the measured data for the compressor outlet pressure versus flow rate, although it is necessary to assume values for certain model parameters which require information about the configuration or dimensions of the compressor components that is unavailable. Unfortunately, the compressor efficiency cannot be compared with experiment data due to the lack of outlet temperature data. A radial inflow turbine model has been developed to enable further comparison of calculations with data from the SBL which incorporates both a radial inflow turbine as well as a radial compressor. Preliminary calculations of pressure ratio and efficiency versus flow rate have been carried out using the radial inflow turbine model.

  6. Essays on economic cycles

    NARCIS (Netherlands)

    Groot, de E.A. (Bert)

    2006-01-01

    Schumpeter’s line of thought of multiple economic cycles is further investigated. The existence of multiple cycles in economic variables is demonstrated. In basic innovations five different cycles are found. Multiple cycle structures are shown in various macro-economic variables from the United

  7. Issues in developing valid assessments of speech pathology students' performance in the workplace.

    Science.gov (United States)

    McAllister, Sue; Lincoln, Michelle; Ferguson, Alison; McAllister, Lindy

    2010-01-01

    Workplace-based learning is a critical component of professional preparation in speech pathology. A validated assessment of this learning is seen to be 'the gold standard', but it is difficult to develop because of design and validation issues. These issues include the role and nature of judgement in assessment, challenges in measuring quality, and the relationship between assessment and learning. Valid assessment of workplace-based performance needs to capture the development of competence over time and account for both occupation specific and generic competencies. This paper reviews important conceptual issues in the design of valid and reliable workplace-based assessments of competence including assessment content, process, impact on learning, measurement issues, and validation strategies. It then goes on to share what has been learned about quality assessment and validation of a workplace-based performance assessment using competency-based ratings. The outcomes of a four-year national development and validation of an assessment tool are described. A literature review of issues in conceptualizing, designing, and validating workplace-based assessments was conducted. Key factors to consider in the design of a new tool were identified and built into the cycle of design, trialling, and data analysis in the validation stages of the development process. This paper provides an accessible overview of factors to consider in the design and validation of workplace-based assessment tools. It presents strategies used in the development and national validation of a tool COMPASS, used in an every speech pathology programme in Australia, New Zealand, and Singapore. The paper also describes Rasch analysis, a model-based statistical approach which is useful for establishing validity and reliability of assessment tools. Through careful attention to conceptual and design issues in the development and trialling of workplace-based assessments, it has been possible to develop the

  8. Nuclear-fuel-cycle education: Module 1. Nuclear fuel cycle overview

    International Nuclear Information System (INIS)

    Eckhoff, N.D.

    1981-07-01

    This educational module is an overview of the nuclear-fule-cycle. The overview covers nuclear energy resources, the present and future US nuclear industry, the industry view of nuclear power, the International Nuclear Fuel Cycle Evaluation program, the Union of Concerned Scientists view of the nuclear-fuel-cycle, an analysis of this viewpoint, resource requirements for a model light water reactor, and world nuclear power considerations

  9. Thorium cycles and proliferation

    International Nuclear Information System (INIS)

    Lovins, A.B.

    1979-01-01

    This paper analyzes several prevalent misconceptions about nuclear fuel cycles that breed fissile uranium-233 from thorium. Its main conclusions are: U-233, despite the gamma radioactivity of associated isotopes, is a rather attractive material for making fission bombs, and is a credible material for subnational as well as national groups to use for this purpose; (2) pure thorium cycles, which in effect merely substitute U-233 for Pu, would take many decades and much U to establish, and offer no significant safeguards advantage over Pu, cycles; (3) denatured Th-U cycles, which dilute the U-233 with inert U-238 to a level not directly usable in bombs, are not an effective safeguard even against subnational bomb-making; (4) several other features of mixed Th-U cycles are rather unattractive from a safeguards point of view; (5) thus, Th cycles of any kind are not a technical fix for proliferation (national or subnational) and, though probably more safeguardable than Pu cycles, are less so than once-through U cycles that entail no reprocessing; (6) while thorium cycles have some potential technical advantages, including flexibility, they cannot provide major savings in nuclear fuel resources compared to simpler ways of saving neutrons and U; and (7) while advocates of nuclear power may find Th cycles worth exploring, such cycles do not differ fundamentally from U cycles in any of the respects--including safeguards and fuel resources--that are relevant to the broader nuclear debate, and should not be euphorically embraced as if they did

  10. Altered cell cycle-related gene expression in brain and lymphocytes from a transgenic mouse model of Alzheimer's disease [amyloid precursor protein/presenilin 1 (PS1)].

    Science.gov (United States)

    Esteras, Noemí; Bartolomé, Fernando; Alquézar, Carolina; Antequera, Desireé; Muñoz, Úrsula; Carro, Eva; Martín-Requero, Ángeles

    2012-09-01

    Cumulative evidence indicates that aberrant re-expression of many cell cycle-related proteins and inappropriate neuronal cell cycle control are critical events in Alzheimer's disease (AD) pathogenesis. Evidence of cell cycle activation in post-mitotic neurons has also been observed in murine models of AD, despite the fact that most of these mice do not show massive loss of neuronal bodies. Dysfunction of the cell cycle appears to affect cells other than neurons, as peripheral cells, such as lymphocytes and fibroblasts from patients with AD, show an altered response to mitogenic stimulation. We sought to determine whether cell cycle disturbances are present simultaneously in both brain and peripheral cells from the amyloid precursor protein (APP)/presenilin 1 (PS1) mouse model of AD, in order to validate the use of peripheral cells from patients not only to study cell cycle abnormalities as a pathogenic feature of AD, but also as a means to test novel therapeutic approaches. By using cell cycle pathway-specific RT(2)Profiler™ PCR Arrays, we detected changes in a number of cell cycle-related genes in brain as well as in lymphocytes from APP/PS1 mice. Moreover, we found enhanced 5'-bromo-2'-deoxyuridine incorporation into DNA in lymphocytes from APP/PS1 mice, and increased expression of the cell proliferation marker proliferating cell nuclear antigen (PCNA), and the cyclin-dependent kinase (CDK) inhibitor Cdkn2a, as detected by immunohistochemistry in cortical neurons of the APP/PS1 mice. Taken together, the cell cycle-related changes in brain and blood cells reported here support the mitosis failure hypothesis in AD and validate the use of peripheral cells as surrogate tissue to study the molecular basis of AD pathogenesis. © 2012 The Authors. European Journal of Neuroscience © 2012 Federation of European Neuroscience Societies and Blackwell Publishing Ltd.

  11. Class 1E software verification and validation: Past, present, and future

    Energy Technology Data Exchange (ETDEWEB)

    Persons, W.L.; Lawrence, J.D.

    1993-10-01

    This paper discusses work in progress that addresses software verification and validation (V&V) as it takes place during the full software life cycle of safety-critical software. The paper begins with a brief overview of the task description and discussion of the historical evolution of software V&V. A new perspective is presented which shows the entire verification and validation process from the viewpoints of a software developer, product assurance engineer, independent V&V auditor, and government regulator. An account of the experience of the field test of the Verification Audit Plan and Report generated from the V&V Guidelines is presented along with sample checklists and lessons learned from the verification audit experience. Then, an approach to automating the V&V Guidelines is introduced. The paper concludes with a glossary and bibliography.

  12. Analysis and modeling of the seasonal South China Sea temperature cycle using remote sensing

    Science.gov (United States)

    Twigt, Daniel J.; de Goede, Erik D.; Schrama, Ernst J. O.; Gerritsen, Herman

    2007-10-01

    The present paper describes the analysis and modeling of the South China Sea (SCS) temperature cycle on a seasonal scale. It investigates the possibility to model this cycle in a consistent way while not taking into account tidal forcing and associated tidal mixing and exchange. This is motivated by the possibility to significantly increase the model’s computational efficiency when neglecting tides. The goal is to develop a flexible and efficient tool for seasonal scenario analysis and to generate transport boundary forcing for local models. Given the significant spatial extent of the SCS basin and the focus on seasonal time scales, synoptic remote sensing is an ideal tool in this analysis. Remote sensing is used to assess the seasonal temperature cycle to identify the relevant driving forces and is a valuable source of input data for modeling. Model simulations are performed using a three-dimensional baroclinic-reduced depth model, driven by monthly mean sea surface anomaly boundary forcing, monthly mean lateral temperature, and salinity forcing obtained from the World Ocean Atlas 2001 climatology, six hourly meteorological forcing from the European Center for Medium range Weather Forecasting ERA-40 dataset, and remotely sensed sea surface temperature (SST) data. A sensitivity analysis of model forcing and coefficients is performed. The model results are quantitatively assessed against climatological temperature profiles using a goodness-of-fit norm. In the deep regions, the model results are in good agreement with this validation data. In the shallow regions, discrepancies are found. To improve the agreement there, we apply a SST nudging method at the free water surface. This considerably improves the model’s vertical temperature representation in the shallow regions. Based on the model validation against climatological in situ and SST data, we conclude that the seasonal temperature cycle for the deep SCS basin can be represented to a good degree. For shallow

  13. Drivers of cycling demand and cycling futures in the Danish context

    DEFF Research Database (Denmark)

    Analysis of the time trend in cycling mode share based on longest possible time series. Logistic regression model of cycling as mode choice as basis for studying ‘driver variables’ contribution to time trend. Describing important vectors of change behind the time trend.......Analysis of the time trend in cycling mode share based on longest possible time series. Logistic regression model of cycling as mode choice as basis for studying ‘driver variables’ contribution to time trend. Describing important vectors of change behind the time trend....

  14. Algebraic approach for the diagnosis of turbine cycles in nuclear power plants

    International Nuclear Information System (INIS)

    Heo, Gyunyoung; Chang, Soon Heung

    2005-01-01

    According to plant operating staff's practical needs, authors proposed a diagnosis model to identify the performance degradation of steam turbine cycles in nuclear power plants (NPPs). The essential idea of this study is how to identify the intrinsically degraded component which causes electric loss. Authors found that there were not so many turbine cycle diagnosis applications in NPPs currently because of technical, financial, or social characteristics of the plant. So a great part of the diagnosis has been dependent on operating staff's experience and knowledge. However as economic competition becomes severe, the efficiency staffs is asking for reliable and practical advisory tools. For the solution of these shortcomings, authors proposed a simple and intuitive diagnosis concept based on the superposition rule of degradation phenomena, which can be derived by simple algebra and correlation analysis. Though the superposition rule is not so significant statistically, almost all of the performance indices under normal operation are fairly compatible with this model. Authors developed a prototype model of quantitative root-cause diagnosis and validated the background theory using the simulated data. The turbine cycle advisory system using this model was applied to Gori NPP units 3 and 4

  15. A full life cycle nuclear knowledge management framework based on digital system

    International Nuclear Information System (INIS)

    Wang, Minglu; Zheng, Mingguang; Tian, Lin; Qiu, Zhongming; Li, Xiaoyan

    2017-01-01

    Highlights: • A full life cycle nuclear power plant knowledge management framework is introduced. • This framework benefits the safe design, construction, operation and maintenance. • This framework enhances safety, economy and reliability of nuclear power plant. - Abstract: The nuclear power plant is highly knowledge-intensive facility. With the rapid advent and development of modern information and communication technology, knowledge management in nuclear industry has been provided with new approaches and possibilities. This paper introduces a full cycle nuclear power plant knowledge management framework based on digital system and tries to find solutions to knowledge creation, sharing, transfer, application and further innovation in nuclear industry. This framework utilizes information and digital technology to build top-tier object driven work environment, automatic design and analysis integration platform, digital dynamic performance Verification & Validation (V&V) platform, collaborative manufacture procedure, digital construction platform, online monitoring and configuration management which benefit knowledge management in NPP full life cycle. The suggested framework will strengthen the design basis of the nuclear power plants (NPPs) and will ensure the safety of the NPP design throughout the whole lifetime of the plant.

  16. Coeficientes de digestibilidad total y de proteínas en alimentos experimentales para juveniles de Oplegnathus insignis (Kner, 1867 (Perciformes, Oplegnathidae

    Directory of Open Access Journals (Sweden)

    Avelino Muñoz

    2015-05-01

    Full Text Available Los alimentos para peces están formulados con diversos ingredientes, donde la harina de pescado es la principal fuente de proteína. Sin embargo, este insumo tiene un alto costo que lleva a la necesidad de evaluar nuevas fuentes de proteínas y probarlas en especies marinas. Oplegnathus insignis (San Pedro, Pacific beakfish es una especie omnívora en su etapa intermareal y carnívora en su etapa submareal, que ha sido cultivada de manera experimental, siendo necesario incorporar dietas formuladas. Este estudio reporta la experiencia en alimentación y nutrición, de juveniles de O. insignis alimentados con dietas formuladas con distintas fuentes de proteína. Se efectuó una experiencia con juveniles de O. insignis provenientes de un cultivo experimental. Se formularon cuatro alimentos, uno en base de harina de pescado (referencia y tres modificando la fuente de proteína del alimento de referencia, intercambiando un 30% de harina de pescado, por harina de soya, harina de moluscos y harina de quinoa. Se experimentó con 180 ind de 295,6 g y de 450 días post-eclosión, distribuidos en 12 estanques rectangulares de 1,6 m³. La alimentación fue a saciedad. Se efectuaron análisis próximales de los alimentos experimentales de las heces colectadas. Se determinó los coeficientes de digestibilidad total y proteína. El alimento con mayor contenido de proteína fue el que contenía harina de moluscos. El mayor coeficiente de digestibilidad total lo tienen los alimentos con harina de pescado (68,0% y harina de moluscos (67,1%, mientras que en los alimentos en base a harinas vegetales, la digestibilidad total para la harina de soya fue de 62,7% y para harina de quinoa de 64,1%. Estos resultados indican que es factible reemplazar un 30% de la harina de pescado por harinas de origen vegetal.

  17. Framework of Strategic Learning: The PDCA Cycle

    Directory of Open Access Journals (Sweden)

    Michał Pietrzak

    2015-06-01

    Full Text Available Nowadays, strategic planning has to be permanent process and organizational learning should support it. Researchers in theories of organizational learning attempt to understand processes, which lead to changes in organizational knowledge, as well as the effects of learning on organizational performance. In traditional approach, the strategy is viewed as one shot event. However, in contemporary turbulent environment this could not be still valid. There is a need of elastic strategic management, which employs organizational learning process. The crucial element of such process is information acquisition, which allows refining the initial version of strategic plan. In this article authors discuss the PDCA cycle as a framework of strategic learning process, including both single-loop and double loop learning. Authors proposed the ideas for further research in area of organizational learning and strategic management.

  18. Assessing Cycling Participation in Australia

    Directory of Open Access Journals (Sweden)

    Chris Rissel

    2013-01-01

    Full Text Available Planning and evaluating cycling programs at a national or state level requires accurate measures of cycling participation. However, recent reports of cycling participation have produced very different estimates. This paper examines the reported rates of cycling in five recent population surveys of cycling. Three surveys (one national and two from Sydney asking respondents when they last rode a bicycle generated cycling participation (cycled in the past year estimates of 29.7%, 34.1% and 28.9%. Two other national surveys which asked participants to recall (unprompted any physical activity done for exercise, recreation or sport in the previous 12 months, estimated cycling in the past year as 11.1% and 6.5%. While unprompted recall of cycling as a type of physical activity generates lower estimates of cycling participation than specific recall questions, both assessment approaches produced similar patterns of cycling by age and sex with both approaches indicating fewer women and older adults cycling. The different question styles most likely explain the substantial discrepancies between the estimates of cycling participation. Some differences are to be expected due to sampling variability, question differences, and regional variation in cycling.

  19. Eficacia de los tratamientos cognitivo-conductuales en el tratamiento del trastorno obsesivo-compulsivo en niños y adolescentes: una revisión cualitativa

    OpenAIRE

    Rosa Alcázar, Ana Isabel; Iniesta Sepúlveda, Marina; Rosa Alcázar, Angel

    2012-01-01

    Se presentan los resultados de un estudio cualitativo de revisión de la eficacia de los tratamientos cognitivo-conductuales utilizados en el trastorno obsesivo-compulsivo en niños y adolescentes. Se localizaron y recuperaron un total de 84 estudios, de los cuales 17 consistían en informes de caso, 37 en diseños de caso único, 19 estudios pre-experimentales con diseño pre-postest, 6 estudios cuasi-experimentales y 5 estudios experimentales con grupo de control. El procedimiento más utilizado...

  20. Méthode expérimentale pour l'identification des modes de cavité très amortis d'un véhicule

    OpenAIRE

    Thevenard , Christophe

    2010-01-01

    National audience; Dans le cadre de la mise au point des véhicules, les essais restent encore indispensables pour construire et valider les modèles numériques vibro-acoustiques. L'aspect purement vibratoire est relativement bien maîtrisé en basses fréquences. En revanche, celui purement acoustique (ie: modes de cavité) souffre d'une difficile caractérisation experimentale en partie dûe aux forts taux d'amortissement (jusqu'à 10%) rencontrés en pratique sur une caisse complète (ie: avec les ha...

  1. Tritium inventories and tritium safety design principles for the fuel cycle of ITER

    International Nuclear Information System (INIS)

    Cristescu, I.R.; Cristescu, I.; Doerr, L.; Glugla, M.; Murdoch, D.

    2007-01-01

    Within the tritium plant of ITER a total inventory of about 2-3 kg will be necessary to operate the machine in the DT phase. During plasma operation, tritium will be distributed in the different sub-systems of the fuel cycle. A tool for tritium inventory evaluation within each sub-system of the fuel cycle is important with respect to both the process of licensing ITER and also for operation. It is very likely that measurements of total tritium inventories may not be possible for all sub-systems; however, tritium accounting may be achieved by modelling its hold-up within each sub-system and by validating these models in real-time against the monitored flows and tritium streams between the sub-systems. To get reliable results, an accurate dynamic modelling of the tritium content in each sub-system is necessary. A dynamic model (TRIMO) for tritium inventory calculation reflecting the design of each fuel cycle sub-systems was developed. The amount of tritium needed for ITER operation has a direct impact on the tritium inventories within the fuel cycle sub-systems. As ITER will function in pulses, the main characteristics that influence the rapid tritium recovery from the fuel cycle as necessary for refuelling are discussed. The confinement of tritium within the respective sub-systems of the fuel cycle is one of the most important safety objectives. The design of the deuterium/tritium fuel cycle of ITER includes a multiple barrier concept for the confinement of tritium. The buildings are equipped with a vent detritiation system and re-circulation type room atmosphere detritiation systems, required for tritium confinement barrier during possible tritium spillage events. Complementarily to the atmosphere detritiation systems, in ITER a water detritiation system for tritium recovery from various sources will also be operated

  2. Life-cycle cost analysis of adsorption cycles for desalination

    KAUST Repository

    Thu, Kyaw; Chakraborty, A.; Saha, B.B.; Chun, Won Gee; Ng, K.C.

    2010-01-01

    This paper presents the thermo-economic analysis of the adsorption desalination (AD) cycle that is driven by low-temperature waste heat from exhaust of industrial processes or renewable sources. The AD cycle uses an adsorbent such as the silica gel

  3. On approximating restricted cycle covers

    NARCIS (Netherlands)

    Manthey, Bodo

    2008-01-01

    A cycle cover of a graph is a set of cycles such that every vertex is part of exactly one cycle. An $L$-cycle cover is a cycle cover in which the length of every cycle is in the set $L$. The weight of a cycle cover of an edge-weighted graph is the sum of the weights of its edges. We come close to

  4. Nuclear power fuel cycle

    International Nuclear Information System (INIS)

    Havelka, S.; Jakesova, L.

    1982-01-01

    Economic problems are discussed of the fuel cycle (cost of the individual parts of the fuel cycle and the share of the fuel cycle in the price of 1 kWh), the technological problems of the fuel cycle (uranium ore mining and processing, uranium isotope enrichment, the manufacture of fuel elements, the building of long-term storage sites for spent fuel, spent fuel reprocessing, liquid and gaseous waste processing), and the ecologic aspects of the fuel cycle. (H.S.)

  5. Benefits of cycle stretchout in pressurized water reactor extended-burnup fuel cycles

    International Nuclear Information System (INIS)

    Matzie, R.A.; Leung, D.C.; Liu, Y.; Beekmann, R.W.

    1981-01-01

    Nuclear reactors are inherently capable of operating for a substantial period beyond their nominal end of cycle (EOC) as a result of negative moderator and fuel temperature coefficients and the decrease in xenon poisoning with lower core power levels. This inherent capability can be used to advantage to reduce annual uranium makeup requirements and cycle energy costs by the use of planned EOC stretchout. This paper discusses the fuel utilization efficiency and economics of both the five-batch, extended-burnup cycle and the three-batch, standard-burnup cycle, which can be improved by employing planned EOC (end of cycle) stretchout. 11 refs

  6. Denatured fuel cycles

    International Nuclear Information System (INIS)

    Till, C.E.

    1979-01-01

    This paper traces the history of the denatured fuel concept and discusses the characteristics of fuel cycles based on the concept. The proliferation resistance of denatured fuel cycles, the reactor types they involve, and the limitations they place on energy generation potential are discussed. The paper concludes with some remarks on the outlook for such cycles

  7. Continuously revised assurance cases with stakeholders’ cross-validation: a DEOS experience

    Directory of Open Access Journals (Sweden)

    Kimio Kuramitsu

    2016-12-01

    Full Text Available Recently, assurance cases have received much attention in the field of software-based computer systems and IT services. However, software changes very often, and there are no strong regulations for software. These facts are two main challenges to be addressed in the development of software assurance cases. We propose a method of developing assurance cases by means of continuous revision at every stage of the system life cycle, including in operation and service recovery in failure cases. Instead of a regulator, dependability arguments are validated by multiple stakeholders competing with each other. This paper reported our experience with the proposed method in the case of Aspen education service. The case study demonstrates that continuous revisions enable stakeholders to share dependability problems across software life cycle stages, which will lead to the long-term improvement of service dependability.

  8. Some experiments on the high-low transition of quartz; Recherches experimentales sur une transformation du quartz

    Energy Technology Data Exchange (ETDEWEB)

    Mayer, G [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1959-12-15

    nombre de resultats numeriques relatifs aux proprietes elastiques, piezoelectriques et optiques du quartz. Certains ont ete collectes dans la litterature; d'autres ont ete obtenus par nous a l'aide de methodes experimentales que nous decrivons, de facon a pouvoir presenter un tableau complet de l'evolution de ces constantes dans un domaine de temperature entourant largement le point de transformation {alpha} - {beta} situe a 574 deg. C. De nouveaux phenomenes ont ete observes au cours de ces mesures. Dans la troisieme partie, nous montrons qu'une meme fonction de la temperature decrit l'evolution de la constante piezoelectrique et de la constante elastique qui s'annulent en phase {beta}. Une seule autre fonction suffit a decrire correctement l'evolution de toutes les autres constantes etudiees, depuis leur valeur en phase {alpha} jusqu'a leur valeur en phase {beta}. A l'aide d'hypotheses sur la nature de l'entropie de transformation, nous essayons enfin d'expliquer la forme de ces fonctions. (auteur)

  9. Edgeworth cycles revisited

    International Nuclear Information System (INIS)

    Doyle, Joseph; Muehlegger, Erich; Samphantharak, Krislert

    2010-01-01

    Some gasoline markets exhibit remarkable price cycles, where price spikes are followed by a series of small price declines: a pattern consistent with a model of Edgeworth cycles described by Maskin and Tirole. We extend the model and empirically test its predictions with a new dataset of daily station-level prices in 115 US cities. Consistent with the theory, and often in contrast with previous empirical work, we find the least and most concentrated markets are much less likely to exhibit cycling behavior both within and across cities; areas with more independent convenience-store gas stations are also more likely to cycle. (author)

  10. Software life cycle process and classification guides for KNICS digital instrumentation and control system design

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jang Soo; Son, Han Seung; Kim, Jang Yeol; Kwon, Kee Choon; Lee, Soon Seung; Kim, Doo Hwan [Korea Atomic Energy Research Institute, Taejeon (Korea)

    2002-04-01

    Documentation should exist that shows that the qualification activities have been successfully accomplished for each life cycle activity group. In particular, the documentation should show that the system safety requirements have been adequately addressed for each life cycle activity group, that no new hazards have been introduced, and that the software requirements, design elements, and code elements that can affect safety have been identified. Because the safety of software can be assured through both the process Verification and Validation (V and V) itself and the V and V of all the intermediate and final products during the software development lifecycle, the development of KNICS Software Safety Framework (KSSF) must be established. As the first activity for establishing KSSF, we have developed this report, Software Life Cycle Process and Classification Guides for KNICS Digital I and C System. This report is organized as follows. Chapter I describes the background, definitions, and references of SLCP. Chapter II describes KNICS safety software categorization. In Chapter III, we define the requirements on software life cycle process for designing digital KNICS. Chapter III.3, that is the main section of the chapter, includes the requirements for software life cycle process planning, the requirements for software life cycle process implementation, and the requirements for software life cycle process design outputs. Finally, we have described the result of a case study on the SLCP for developing the software of ESF-CCS system that is being developed by a private company, BNF. 29 refs., 5 figs., 7 tabs. (Author)

  11. Fuel cycle management

    International Nuclear Information System (INIS)

    Herbin, H.C.

    1977-01-01

    The fuel cycle management is more and more dependent on the management of the generation means among the power plants tied to the grid. This is due mainly because of the importance taken by the nuclear power plants within the power system. The main task of the fuel cycle management is to define the refuelling pattern of the new and irradiated fuel assemblies to load in the core as a function of: 1) the differences which exist between the actual conditions of the core and what was expected for the present cycle, 2) the operating constraints and the reactor availability, 3) the technical requirements in safety and the technological limits of the fuel, 4) the economics. Three levels of fuel cycle management can be considered: 1) a long term management: determination of enrichments and expected cycle lengths, 2) a mid term management whose aim corresponds to the evaluation of the batch to load within the core as a function of both: the next cycle length to achieve and the integrated power history of all the cycles up to the present one, 3) a short term management which deals with the updating of the loaded fuel utilisations to take into account the operation perturbations, or with the alteration of the loading pattern of the next batch to respect unexpected conditions. (orig.) [de

  12. Improvement of supercritical CO2 Brayton cycle using binary gas mixture

    International Nuclear Information System (INIS)

    Jeong, Woo Seok

    2011-02-01

    simple recuperated layout and recompression layout Brayton cycles. For verification, existing design values of GTHTR 300, based on helium Brayton cycle, were used. Main input parameters were referred to Dostal's work as a reference cycle. The cycle performance evaluations were conducted for CO 2 -He, CO 2 -Ar, CO 2 -N 2 and CO 2 -O 2 binary mixtures by the developed cycle code. CO 2 -Xe mixture cycle was excluded in the pre-analysis since there is no mixture data. The mixed ratio of adding component was adjusted to specify the same critical temperature to be unbiased. The difference of binary gas mixture cycles compared to S-CO 2 cycle was decrease in minimum cycle temperature and changes in minimum pressure and working fluids. Through the simulation, the CO 2 -He binary mixture was found out to be the highest increase of cycle efficiency: 1.73 % when the critical temperature was at 292 K for recompression cycle layout. Unlike the CO 2 -He binary mixture, the cycle efficiencies of CO 2 -Ar, CO 2 -N 2 , and CO 2 -O 2 binary mixtures decreased compared to the pure S-CO 2 cycle: -0.71 %, -1.35 % and -1.16 %, respectively. It was found that the increment of critical pressure led to a decrease in cycle operating pressure ratio which resulted in a negative effect on total cycle efficiency. The validation for the simulation was conducted by measuring the critical point of CO 2 -He mixture. The result clearly showed that the both critical temperature and critical pressure increase while the amount of added helium increases. The prediction of the property program indicates the opposite result and it means that the simulated CO 2 -He cycle is not a supercritical Brayton cycle. For the option of CO 2 -Xe mixture, the properties can be calculated based on ideal mixing rule and also can be modified with experimental data. With the proposed method, the efficiency of CO 2 -Xe mixture cycle is expected to increase by 1.28 %

  13. Validation experience with the core calculation program karate

    International Nuclear Information System (INIS)

    Hegyi, Gy.; Hordosy, G.; Kereszturi, A.; Makai, M.; Maraczy, Cs.

    1995-01-01

    A relatively fast and easy-to-handle modular code system named KARATE-440 has been elaborated for steady-state operational calculations of VVER-440 type reactors. It is built up from cell, assembly and global calculations. In the frame of the program neutron physical and thermohydraulic process of the core at normal startup, steady and slow transient can be simulated. The verification and validation of the global code have been prepared recently. The test cases include mathematical benchmark and measurements on operating VVER-440 units. Summary of the results, such as startup parameters, boron letdown curves, radial and axial power distributions of some cycles of Paks NPP is presented. (author)

  14. ORIGEN-based Nuclear Fuel Inventory Module for Fuel Cycle Assessment: Final Project Report

    Energy Technology Data Exchange (ETDEWEB)

    Skutnik, Steven E. [Univ. of Tennessee, Knoxville, TN (United States). Dept. of Nuclear Engineering

    2017-06-19

    The goal of this project, “ORIGEN-based Nuclear Fuel Depletion Module for Fuel Cycle Assessment" is to create a physics-based reactor depletion and decay module for the Cyclus nuclear fuel cycle simulator in order to assess nuclear fuel inventories over a broad space of reactor operating conditions. The overall goal of this approach is to facilitate evaluations of nuclear fuel inventories for a broad space of scenarios, including extended used nuclear fuel storage and cascading impacts on fuel cycle options such as actinide recovery in used nuclear fuel, particularly for multiple recycle scenarios. The advantages of a physics-based approach (compared to a recipe-based approach which has been typically employed for fuel cycle simulators) is in its inherent flexibility; such an approach can more readily accommodate the broad space of potential isotopic vectors that may be encountered under advanced fuel cycle options. In order to develop this flexible reactor analysis capability, we are leveraging the Origen nuclear fuel depletion and decay module from SCALE to produce a standalone “depletion engine” which will serve as the kernel of a Cyclus-based reactor analysis module. The ORIGEN depletion module is a rigorously benchmarked and extensively validated tool for nuclear fuel analysis and thus its incorporation into the Cyclus framework can bring these capabilities to bear on the problem of evaluating long-term impacts of fuel cycle option choices on relevant metrics of interest, including materials inventories and availability (for multiple recycle scenarios), long-term waste management and repository impacts, etc. Developing this Origen-based analysis capability for Cyclus requires the refinement of the Origen analysis sequence to the point where it can reasonably be compiled as a standalone sequence outside of SCALE; i.e., wherein all of the computational aspects of Origen (including reactor cross-section library processing and interpolation, input and output

  15. Exergoeconomic comparison of TLC (trilateral Rankine cycle), ORC (organic Rankine cycle) and Kalina cycle using a low grade heat source

    International Nuclear Information System (INIS)

    Yari, M.; Mehr, A.S.; Zare, V.; Mahmoudi, S.M.S.; Rosen, M.A.

    2015-01-01

    Recently, the TLC (trilateral power cycle) has attracted significant interest as it provides better matching between the temperature profiles in the evaporator compared to conventional power cycles. This article investigates the performance of this cycle and compares it with those for the ORC (organic Rankine cycle) and the Kalina cycle, from the viewpoints of thermodynamics and thermoeconomics. A low-grade heat source with a temperature of 120 °C is considered for all the three systems. Parametric studies are performed for the systems for several working fluids in the ORC and TLC. The systems are then optimized for either maximum net output power or minimum product cost, using the EES (engineering equation solver) software. The results for the TLC indicate that an increase in the expander inlet temperature leads to an increase in net output power and a decrease in product cost for this power plant, whereas this is not the case for the ORC system. It is found that, although the TLC can achieve a higher net output power compared with the ORC and Kalina (KCS11 (Kalina cycle system 11)) systems, its product cost is greatly affected by the expander isentropic efficiency. It is also revealed that using n-butane as the working fluid can result in the lowest product cost in the ORC and the TLC. In addition, it is observed that, for both the ORC and Kalina systems, the optimum operating condition for maximum net output power differs from that for minimum product cost. - Highlights: • Exergoeconomic analysis of trilateral Rankine cycle is performed. • The system performance is compared with Organic Rankine and Kalina cycles. • Net power from trilateral Rankine cycle is higher than the other power systems. • Superiority of trilateral cycle depends on its expander isentropic efficiency

  16. Caracterisation experimentale de la transmission acoustique de structures aeronautiques

    Science.gov (United States)

    Pointel, Vincent

    Le confort des passagers à l'intérieur des avions pendant le vol est un axe en voie d'amélioration constante. L'augmentation de la proportion des matériaux composites dans la fabrication des structures aéronautiques amène de nouvelles problématiques à résoudre. Le faible amortissement de ces structures, en contre partie de leur poids/raideur faible, est non favorable sur le plan acoustique, ce qui oblige les concepteurs à devoir trouver des moyens d'amélioration. De plus, les mécanismes de transmission du son au travers d'un système double paroi de type aéronautique ne sont pas complètement compris, c'est la raison qui motive cette étude. L'objectif principal de ce projet est de constituer une base de données pour le partenaire industriel de ce projet : Bombardier Aéronautique. En effet, les données expérimentales de performance d'isolation acoustique, de systèmes complets représentatifs d'un fuselage d'avion sont très rares dans la littérature scientifique. C'est pourquoi une méthodologie expérimentale est utilisée dans ce projet. Deux conceptions différentes de fuselage sont comparées. La première possède une peau (partie extérieure du fuselage) métallique raidie, alors que la deuxième est constituée d'un panneau sandwich composite. Dans les deux cas, un panneau de finition de fabrication sandwich est utilisé. Un traitement acoustique en laine de verre est placé à l'intérieur de chacun des fuselages. Des isolateurs vibratoires sont utilisés pour connecter les deux panneaux du fuselage. La simulation en laboratoire de la couche limite turbulente, qui est la source d'excitation prépondérante pendant la phase de vol, n'est pas encore possible hormis en soufflerie. C'est pourquoi deux cas d'excitation sont considérés pour essayer d'approcher cette sollicitation : une excitation mécanique (pot vibrant) et une acoustique (champ diffus). La validation et l'analyse des résultats sont effectuées par le biais des logiciels

  17. Isthmus Dependent Atrial Flutter Cycle Length Correlates with Right Atrial Cross-Sectional Area

    Directory of Open Access Journals (Sweden)

    Kousik Krishnan

    2009-05-01

    Full Text Available Background: Right atrial flutter cycle length can prolong in the presence of antiarrhythmic drug therapy. We hypothesized that the cycle length of right atrial isthmus dependent flutter would correlate with right atrial cross-sectional area measurements. Methods: 60 patients who underwent ablation for electrophysiologically proven isthmus dependent right atrial flutter, who were not on Class I or Class III antiarrhythmic drugs and had recent 2-dimensional echocardiographic data comprised the study group. Right atrial length and width were measured in the apical four chamber view. Cross-sectional area was estimated by multiplying the length and width. 35 patients had an atrial flutter rate ≥250 bpm (Normal Flutter Group and 25 patients had an atrial flutter rate < 250 bpm (Slow Flutter Group. Results: Mean atrial flutter rate was 283 bpm in the normal flutter group and 227 bpm in the slow flutter group. Mean atrial flutter cycle length was 213 ms in the Normal Flutter Group and 265 ms in the Slow Flutter Group (p<0.0001. Mean right atrial cross sectional area was 1845 mm2 in the Normal Flutter group and 2378 mm2 in the Slow Flutter Group, (p< 0.0001. Using linear regression, CSA was a significant predictor of cycle length (β =0.014 p = 0.0045. For every 1 mm2 increase in cross-sectional area, cycle length is 0.014 ms longer.Conclusion: In the absence of antiarrhythmic medications, right atrial cross sectional area enlargement correlates with atrial flutter cycle length. These findings provide further evidence that historical rate-related definitions of typical isthmus dependent right atrial are not mechanistically valid.

  18. Out-of-core fuel cycle optimization for nonequilibrium cycles

    International Nuclear Information System (INIS)

    Comes, S.A.; Turinsky, P.J.

    1988-01-01

    A methodology has been developed for determining the family of near-optimum fuel management schemes that minimize the levelized fuel cycle costs of a light water reactor over a multicycle planning horizon. Feed batch enrichments and sizes, burned batches to reinsert, and burnable poison loadings are determined for each cycle in the planning horizon. Flexibility in the methodology includes the capability to assess the economic benefits of various partially burned bath reload strategies as well as the effects of using split feed enrichments and enrichment palettes. Constraint limitations are imposed on feed enrichments, discharge burnups, moderator temperature coefficient, and cycle energy requirements

  19. Hypersonic Experimental and Computational Capability, Improvement and Validation. Volume 2. (l’Hypersonique experimentale et de calcul - capacite, ameliorafion et validation)

    Science.gov (United States)

    1998-12-01

    Reactive Gas Flows Within Shock Tunnels", Australian Journal of Physics, 37 (2) 157-177 (1984). 24 Hannemann , K., and Brenner, G., "Numeri- cal... Hannemann K., Butefisch K., Koppenwallner G. 1991 Review of the European Hypersonic Wind Tunnel Performance and Simulation Requirements. ESA Paper

  20. A standardized approach to verification and validation to assist in expert system development

    International Nuclear Information System (INIS)

    Hines, J.W.; Hajek, B.K.; Miller, D.W.; Haas, M.A.

    1992-01-01

    For the past six years, the Nuclear Engineering Program's Artificial Intelligence (AI) Group at The Ohio State University has been developing an integration of expert systems to act as an aid to nuclear power plant operators. This Operator Advisor consists of four modules that monitor plant parameters, detect deviations from normality, diagnose the root cause of the abnormality, manage procedures to effectively respond to the abnormality, and mitigate its consequences. To aid in the development of this new system, a standardized Verification and Validation (V and V) approach is being implemented. The primary functions are to guide the development of the expert system and to ensure that the end product fulfills the initial objectives. The development process has been divided into eight life-cycle V and V phases from concept to operation and maintenance. Each phase has specific V and V tasks to be performed to ensure a quality end product. Four documents are being used to guide development. The Software Verification and Validation Plan (SVVP) outlines the V and V tasks necessary to verify the product at the end of each software development phase, and to validate that the end product complies with the established software and system requirements and meets the needs of the user. The Software Requirements Specification (SRS) documents the essential requirements of the system. The Software Design Description (SDD) represents these requirements with a specific design. And lastly, the Software Test Document establishes a testing methodology to be used throughout the development life-cycle

  1. Experimental studies on optimal process of the iodine-sulfur cycle for nuclear hydrogen production

    Energy Technology Data Exchange (ETDEWEB)

    Yoon, Ho Joon

    2010-02-15

    For nuclear hydrogen production, we selected Iodine-Sulfur (I-S) cycle as the most promising one by screening process among 115 thermo-chemical water splitting technologies. We developed a thermo-physical model for the hydrogen-iodide (HI) VLE and decomposition behavior in the iodine-sulfur (IS) cycle to improve the conventional I-S cycle suggested by GA. Neumann's modified NRTL model was improved by correcting an unphysical assumption for the non-randomness parameter, and using the two-step equilibrium approach for the HI decomposition modeling. However, the parameters of the model were decided through regression with the 271 sets of existing experimental data: the accuracy of the model should be improved by more experimental data over all operating ranges, especially, in the high temperature and high pressure regions. To obtain the data of those regions, an autoclave for high temperature and high pressure was designed and manufactured. Various materials and surface coating technologies were investigated for preventing corrosion from acids. However, we have currently failed to overcome the corrosion problems with highly corrosive acids at a high temperature and high pressure. We experimentally validated that azeotropic constraint between acid and H{sub 2}O undermined the total efficiency of the I-S cycle. As mentioned above, the conventional I-S cycle suffers from low thermal efficiency and highly corrosive streams. To alleviate these problems, we have proposed the optimal operating conditions for the Bunsen reaction and devised a new KAIST flowsheet that produces highly enriched HI through spontaneous L-L phase separation and simple flash processes under low pressure. A series of phase separation experiments were performed to validate the new flowsheet and extend its feasibility. When the molar ratio of I{sub 2}/H{sub 2}SO{sub 4} in the feed increased from 2 to 4, the molar ratio of HI/(HI+H{sub 2}O) in the HI{sub x} phase improved from 0.157 to 0.22, which

  2. Experimental studies on optimal process of the iodine-sulfur cycle for nuclear hydrogen production

    International Nuclear Information System (INIS)

    Yoon, Ho Joon

    2010-02-01

    For nuclear hydrogen production, we selected Iodine-Sulfur (I-S) cycle as the most promising one by screening process among 115 thermo-chemical water splitting technologies. We developed a thermo-physical model for the hydrogen-iodide (HI) VLE and decomposition behavior in the iodine-sulfur (IS) cycle to improve the conventional I-S cycle suggested by GA. Neumann's modified NRTL model was improved by correcting an unphysical assumption for the non-randomness parameter, and using the two-step equilibrium approach for the HI decomposition modeling. However, the parameters of the model were decided through regression with the 271 sets of existing experimental data: the accuracy of the model should be improved by more experimental data over all operating ranges, especially, in the high temperature and high pressure regions. To obtain the data of those regions, an autoclave for high temperature and high pressure was designed and manufactured. Various materials and surface coating technologies were investigated for preventing corrosion from acids. However, we have currently failed to overcome the corrosion problems with highly corrosive acids at a high temperature and high pressure. We experimentally validated that azeotropic constraint between acid and H 2 O undermined the total efficiency of the I-S cycle. As mentioned above, the conventional I-S cycle suffers from low thermal efficiency and highly corrosive streams. To alleviate these problems, we have proposed the optimal operating conditions for the Bunsen reaction and devised a new KAIST flowsheet that produces highly enriched HI through spontaneous L-L phase separation and simple flash processes under low pressure. A series of phase separation experiments were performed to validate the new flowsheet and extend its feasibility. When the molar ratio of I 2 /H 2 SO 4 in the feed increased from 2 to 4, the molar ratio of HI/(HI+H 2 O) in the HI x phase improved from 0.157 to 0.22, which is high enough to generate

  3. Assessing the validity of impact pathways for child labour and well-being in Social Life Cycle Assessment

    DEFF Research Database (Denmark)

    Jørgensen, Andreas; Lai, Lufanna CH; Hauschild, Michael Zwicky

    2010-01-01

    have a consistent theoretical foundation so the inventory results can be associated with a predictable damage or benefit to the AoP. This article uses two concrete examples from the work on SLCA to analyse to what extent this is the case in current practice. One considers whether indicators included...... exclusively with the type of indicators which are presently used in SLCA approaches. The second example shows that the mere fact that a child is working tells little about how this may damage or benefit the AoPs, implying that the normally used indicator; ‘incidence of child labour’ lacks validity in relation......, boundary setting issues. Conclusions The article shows that it is possible to assess the validity of the impact pathways in SLCA. It thereby point to the possibility of utilising the same framework that underpins the environmental LCA in this regard. It also shows that in relation to both of the specific...

  4. Air bottoming cycle, an alternative to combined cycles. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Kaikko, J. [Royal Inst. of Techn., Stockholm (Sweden). Dept. of Energy Technology

    2001-10-01

    In this work, the idea of Air Bottoming Cycle (ABC) has been studied. The objectives for the work have been to establish an understanding of the concept for power and heat generation as well as to find - if possible - feasible concepts for future use in the Swedish energy system. Combined cycle in power generation is an established technology. In the conventional combined cycle, a gas turbine works as a topping cycle together with the steam (Rankine) bottoming cycle. In the ABC the steam bottoming cycle is replaced with a gas turbine (Brayton) bottoming cycle having air as a working fluid. The two gas turbines are thermally connected over a gas-to-gas heat exchanger. This concept promises savings in weight and cost, as well as operating benefits, compared to the Rankine bottoming technology. The ABC has been modelled using a heat balance program, and a parametric study for the concept optimisation as well as for off-design analysis has been performed. Performance of the ABC has been compared to other, established technologies. A preliminary economic evaluation has been made. As a result of the study, it is clarified that the Rankine bottoming cycle with steam remains superior to the ABC as regards electrical efficiency in the medium and large power scale. For small-scale applications (<10 MW{sub e}) where the thermodynamic advantage of the Rankine cycle is not dominating any longer and its economy is burdened by the heavy investment structure, the ABC becomes the better alternative for energy utilisation. A preliminary economic evaluation shows that (at energy prices autumn 2000) the ABC is at the same level as the comparable small-scale cogeneration installations. Due to high power-to-heat ratio however, higher electricity prices will favour the ABC. One interesting feature of the ABC is that about 50% of the dissipated low-value heat from the cycle is carried by clean (sterile) air at the temperature around 200 deg C. This air can be utilised for space heating or

  5. Design for validation: An approach to systems validation

    Science.gov (United States)

    Carter, William C.; Dunham, Janet R.; Laprie, Jean-Claude; Williams, Thomas; Howden, William; Smith, Brian; Lewis, Carl M. (Editor)

    1989-01-01

    Every complex system built is validated in some manner. Computer validation begins with review of the system design. As systems became too complicated for one person to review, validation began to rely on the application of adhoc methods by many individuals. As the cost of the changes mounted and the expense of failure increased, more organized procedures became essential. Attempts at devising and carrying out those procedures showed that validation is indeed a difficult technical problem. The successful transformation of the validation process into a systematic series of formally sound, integrated steps is necessary if the liability inherent in the future digita-system-based avionic and space systems is to be minimized. A suggested framework and timetable for the transformtion are presented. Basic working definitions of two pivotal ideas (validation and system life-cyle) are provided and show how the two concepts interact. Many examples are given of past and present validation activities by NASA and others. A conceptual framework is presented for the validation process. Finally, important areas are listed for ongoing development of the validation process at NASA Langley Research Center.

  6. Relation Between the Cell Volume and the Cell Cycle Dynamics in Mammalian cell

    International Nuclear Information System (INIS)

    Magno, A.C.G.; Oliveira, I.L.; Hauck, J.V.S.

    2016-01-01

    The main goal of this work is to add and analyze an equation that represents the volume in a dynamical model of the mammalian cell cycle proposed by Gérard and Goldbeter (2011) [1]. The cell division occurs when the cyclinB/Cdkl complex is totally degraded (Tyson and Novak, 2011)[2] and it reaches a minimum value. At this point, the cell is divided into two newborn daughter cells and each one will contain the half of the cytoplasmic content of the mother cell. The equations of our base model are only valid if the cell volume, where the reactions occur, is constant. Whether the cell volume is not constant, that is, the rate of change of its volume with respect to time is explicitly taken into account in the mathematical model, then the equations of the original model are no longer valid. Therefore, every equations were modified from the mass conservation principle for considering a volume that changes with time. Through this approach, the cell volume affects all model variables. Two different dynamic simulation methods were accomplished: deterministic and stochastic. In the stochastic simulation, the volume affects every model's parameters which have molar unit, whereas in the deterministic one, it is incorporated into the differential equations. In deterministic simulation, the biochemical species may be in concentration units, while in stochastic simulation such species must be converted to number of molecules which are directly proportional to the cell volume. In an effort to understand the influence of the new equation a stability analysis was performed. This elucidates how the growth factor impacts the stability of the model's limit cycles. In conclusion, a more precise model, in comparison to the base model, was created for the cell cycle as it now takes into consideration the cell volume variation (paper)

  7. Validation and Error Characterization for the Global Precipitation Measurement

    Science.gov (United States)

    Bidwell, Steven W.; Adams, W. J.; Everett, D. F.; Smith, E. A.; Yuter, S. E.

    2003-01-01

    The Global Precipitation Measurement (GPM) is an international effort to increase scientific knowledge on the global water cycle with specific goals of improving the understanding and the predictions of climate, weather, and hydrology. These goals will be achieved through several satellites specifically dedicated to GPM along with the integration of numerous meteorological satellite data streams from international and domestic partners. The GPM effort is led by the National Aeronautics and Space Administration (NASA) of the United States and the National Space Development Agency (NASDA) of Japan. In addition to the spaceborne assets, international and domestic partners will provide ground-based resources for validating the satellite observations and retrievals. This paper describes the validation effort of Global Precipitation Measurement to provide quantitative estimates on the errors of the GPM satellite retrievals. The GPM validation approach will build upon the research experience of the Tropical Rainfall Measuring Mission (TRMM) retrieval comparisons and its validation program. The GPM ground validation program will employ instrumentation, physical infrastructure, and research capabilities at Supersites located in important meteorological regimes of the globe. NASA will provide two Supersites, one in a tropical oceanic and the other in a mid-latitude continental regime. GPM international partners will provide Supersites for other important regimes. Those objectives or regimes not addressed by Supersites will be covered through focused field experiments. This paper describes the specific errors that GPM ground validation will address, quantify, and relate to the GPM satellite physical retrievals. GPM will attempt to identify the source of errors within retrievals including those of instrument calibration, retrieval physical assumptions, and algorithm applicability. With the identification of error sources, improvements will be made to the respective calibration

  8. CFD aided approach to design printed circuit heat exchangers for supercritical CO2 Brayton cycle application

    International Nuclear Information System (INIS)

    Kim, Seong Gu; Lee, Youho; Ahn, Yoonhan; Lee, Jeong Ik

    2016-01-01

    Highlights: • CFD analyses were performed to find performance of PCHE for supercritical CO 2 power cycle. • CFD results were obtained beyond the limits of existing correlations. • Designs of different PCHEs with different correlations were compared. • A new CFD-aided correlation covering a wider Reynolds number range was proposed. - Abstract: While most conventional PCHE designs for working fluid of supercritical CO 2 require an extension of valid Reynolds number limits of experimentally obtained correlations, Computational Fluid Dynamics (CFD) code ANSYS CFX was used to explore validity of existing correlations beyond their tested Reynolds number ranges. For heat transfer coefficient correlations, an appropriate piece-wising with Ishizuka’s and Hesselgreaves’s correlation is found to enable an extension of Reynolds numbers. For friction factors, no single existing correlation is found to capture different temperature and angular dependencies for a wide Reynolds number range. Based on the comparison of CFD results with the experimentally obtained correlations, a new CFD-aided correlation covering an extended range of Reynolds number 2000–58,000 for Nusselt number and friction factor is proposed to facilitate PCHE designs for the supercritical CO 2 Brayton cycle application.

  9. Measuring the Changes in Aggregate Cycling Patterns between 2003 and 2012 from a Space Syntax Perspective

    Directory of Open Access Journals (Sweden)

    Stephen Law

    2014-08-01

    external built environment as measured by the spatial configuration measure relates to aggregated cyclists movement overtime and in identifying key potential factors in influencing cyclist wayfinding. Further research is needed into validating the results and examining this relationship at an individual basis on route choice. These results help us better understand the trade off between cycling safety and cycling legibility which could help inform cycling route design in the future.

  10. Validation of the Pulmonary Function System for Use on the International Space Station

    Science.gov (United States)

    McCleary, Frank A.; Moore, Alan D., Jr.; Hagan, R. Donald

    2007-01-01

    Aerobic deconditioning occurs during long duration space flight despite the use of exercise countermeasures (Convertino, 1996). As a part of International Space Station (ISS) medical operations, periodic tests designed to estimate aerobic capacity are performed to track changes in aerobic fitness and to determine the effectiveness of exercise countermeasures. These tests are performed prior to, during, and after missions of greater than 30 days in duration. Crewmembers selected for missions aboard the ISS perform a graded exercise test on a cycle ergometer approximately 270 days prior to their scheduled launch date in order to measure peak oxygen consumption (VO2PK) and peak heart rate (HRpk). Approximately 30 to 45 days prior to launch, crewmembers perform a submaximal cycle ergometer test at work rates set to elicit 25, 50 and 75% of their pre-flight VO2PK. This test, known as the Periodic Fitness Evaluation (PFE), serves as a baseline measure to which subsequent in-and post-flight exercise tests are compared. While onboard the ISS, crewmembers are normally scheduled to perform the PFE beginning with flight day (FD) 14 and every 30 days thereafter. The PFE is also conducted 5 and 30 days following flight. Using PFE data, aerobic fitness is estimated by quantifying the VO2 vs. HR relationship using linear regression and calculating the VO2 that would occur at the crewmember s previously measured HRpk. Currently, for data collected during flight, this technique assumes that the pre- vs. in-flight oxygen consumption per given cycle workload is similar. However, the validity of this assumption is based upon a sparse amount of data collected during the Skylab era (Michel, et al. 1977). The method of using heart rate and cycle ergometer work rates has been used to estimate aerobic fitness in normal gravity (Astrand and Ryhming, 1954; Lee, 1993). Due to spaceflight induced physiological alterations, such as shifts in extracellular fluid (e.g. plasma) volume, this method

  11. Experimental benchmark of non-local-thermodynamic-equilibrium plasma atomic physics codes; Validation experimentale des codes de physique atomique des plasmas hors equilibre thermodynamique local

    Energy Technology Data Exchange (ETDEWEB)

    Nagels-Silvert, V

    2004-09-15

    The main purpose of this thesis is to get experimental data for the testing and validation of atomic physics codes dealing with non-local-thermodynamical-equilibrium plasmas. The first part is dedicated to the spectroscopic study of xenon and krypton plasmas that have been produced by a nanosecond laser pulse interacting with a gas jet. A Thomson scattering diagnostic has allowed us to measure independently plasma parameters such as electron temperature, electron density and the average ionisation state. We have obtained time integrated spectra in the range between 5 and 10 angstroms. We have identified about one hundred xenon rays between 8.6 and 9.6 angstroms via the use of the Relac code. We have discovered unknown rays for the krypton between 5.2 and 7.5 angstroms. In a second experiment we have extended the wavelength range to the X UV domain. The Averroes/Transpec code has been tested in the ranges from 9 to 15 angstroms and from 10 to 130 angstroms, the first range has been well reproduced while the second range requires a more complex data analysis. The second part is dedicated to the spectroscopic study of aluminium, selenium and samarium plasmas in femtosecond operating rate. We have designed an interferometry diagnostic in the frequency domain that has allowed us to measure the expanding speed of the target's backside. Via the use of an adequate isothermal model this parameter has led us to know the plasma electron temperature. Spectra and emission times of various rays from the aluminium and selenium plasmas have been computed satisfactorily with the Averroes/Transpec code coupled with Film and Multif hydrodynamical codes. (A.C.)

  12. Experimental benchmark of non-local-thermodynamic-equilibrium plasma atomic physics codes; Validation experimentale des codes de physique atomique des plasmas hors equilibre thermodynamique local

    Energy Technology Data Exchange (ETDEWEB)

    Nagels-Silvert, V

    2004-09-15

    The main purpose of this thesis is to get experimental data for the testing and validation of atomic physics codes dealing with non-local-thermodynamical-equilibrium plasmas. The first part is dedicated to the spectroscopic study of xenon and krypton plasmas that have been produced by a nanosecond laser pulse interacting with a gas jet. A Thomson scattering diagnostic has allowed us to measure independently plasma parameters such as electron temperature, electron density and the average ionisation state. We have obtained time integrated spectra in the range between 5 and 10 angstroms. We have identified about one hundred xenon rays between 8.6 and 9.6 angstroms via the use of the Relac code. We have discovered unknown rays for the krypton between 5.2 and 7.5 angstroms. In a second experiment we have extended the wavelength range to the X UV domain. The Averroes/Transpec code has been tested in the ranges from 9 to 15 angstroms and from 10 to 130 angstroms, the first range has been well reproduced while the second range requires a more complex data analysis. The second part is dedicated to the spectroscopic study of aluminium, selenium and samarium plasmas in femtosecond operating rate. We have designed an interferometry diagnostic in the frequency domain that has allowed us to measure the expanding speed of the target's backside. Via the use of an adequate isothermal model this parameter has led us to know the plasma electron temperature. Spectra and emission times of various rays from the aluminium and selenium plasmas have been computed satisfactorily with the Averroes/Transpec code coupled with Film and Multif hydrodynamical codes. (A.C.)

  13. 'Benefits cycle' replacing premium cycle as consumerism takes hold.

    Science.gov (United States)

    2002-05-01

    The traditional premium cycle of ups and downs in rates is giving way to a new phenomenon--driven by the advent of consumerism in health care--termed the "benefits cycle" by one consultant. Rather than shifts in rates, he argues, the future will see shifts in benefits packages.

  14. Honeybee Colony Vibrational Measurements to Highlight the Brood Cycle.

    Directory of Open Access Journals (Sweden)

    Martin Bencsik

    Full Text Available Insect pollination is of great importance to crop production worldwide and honey bees are amongst its chief facilitators. Because of the decline of managed colonies, the use of sensor technology is growing in popularity and it is of interest to develop new methods which can more accurately and less invasively assess honey bee colony status. Our approach is to use accelerometers to measure vibrations in order to provide information on colony activity and development. The accelerometers provide amplitude and frequency information which is recorded every three minutes and analysed for night time only. Vibrational data were validated by comparison to visual inspection data, particularly the brood development. We show a strong correlation between vibrational amplitude data and the brood cycle in the vicinity of the sensor. We have further explored the minimum data that is required, when frequency information is also included, to accurately predict the current point in the brood cycle. Such a technique should enable beekeepers to reduce the frequency with which visual inspections are required, reducing the stress this places on the colony and saving the beekeeper time.

  15. Effects of Amplitude Variations on Deformation and Damage Evolution in SnAgCu Solder in Isothermal Cycling

    Science.gov (United States)

    Wentlent, Luke; Alghoul, Thaer M.; Greene, Christopher M.; Borgesen, Peter

    2018-02-01

    Although apparently simpler than in thermal cycling, the behavior of SnAgCu (SAC) solder joints in cyclic bending or vibration is not currently well understood. The rate of damage has been shown to scale with the inelastic work per cycle, and excursions to higher amplitudes lead to an apparent softening, some of which remains so that damage accumulation is faster in subsequent cycling at lower amplitudes. This frequently leads to a dramatic breakdown of current damage accumulation rules. An empirical damage accumulation rule has been proposed to account for this, but any applicability to the extrapolation of accelerated test results to life under realistic long-term service conditions remains to be validated. This will require a better understanding of the underlying mechanisms. The present work provides experimental evidence to support recent suggestions that the observed behavior is a result of cycling-induced dislocation structures providing for increased diffusion creep. It is argued that this means that the measured work is an indicator of the instantaneous dislocation density, rather than necessarily reflecting the actual work involved in the creation of the damage.

  16. Class 1E software verification and validation: Past, present, and future

    International Nuclear Information System (INIS)

    Persons, W.L.; Lawrence, J.D.

    1993-10-01

    This paper discusses work in progress that addresses software verification and validation (V ampersand V) as it takes place during the full software life cycle of safety-critical software. The paper begins with a brief overview of the task description and discussion of the historical evolution of software V ampersand V. A new perspective is presented which shows the entire verification and validation process from the viewpoints of a software developer, product assurance engineer, independent V ampersand V auditor, and government regulator. An account of the experience of the field test of the Verification Audit Plan and Report generated from the V ampersand V Guidelines is presented along with sample checklists and lessons learned from the verification audit experience. Then, an approach to automating the V ampersand V Guidelines is introduced. The paper concludes with a glossary and bibliography

  17. Class 1E software verification and validation: Past, present, and future

    International Nuclear Information System (INIS)

    Persons, W.L.; Lawrence, J.D.

    1994-01-01

    This paper discusses work in progress that addresses software verification and validation (V ampersand V) as it takes place during the full software life cycle of safety-critical software. The paper begins with a brief overview of the task description and discussion of the historical evolution of software V ampersand V. A new perspective is presented which shows the entire verification and validation process from the viewpoints of a software developer, product assurance engineer, independent V ampersand V auditor, and government regulator. An account of the experience of the field test of the Verification Audit Plan and Report generated from the V ampersand V Guidelines is presented along with sample checklists and lessons learned from the verification audit experience. Then, an approach to automating the V ampersand V Guidelines is introduced. The paper concludes with a glossary and bibliography

  18. Validation of main nuclear libraries used in thorium reactors using the Serpent code

    International Nuclear Information System (INIS)

    Faga, Lucas J.

    2017-01-01

    The purpose of this work is to validate the library of the Serpent standard database for systems containing U-233, U-235, Th-232, Pu-239 and Pu-240. The project will support the other projects of the newly created study group of Nuclear Engineering Center (CEN) of Instituto de Pesquisas Energéticas e Nucleares (IPEN), linked to the study of several types of reactors and their application in thorium cycles, a subject that gains more and more visibility, due to strong and potential promises of energy revolution. The results obtained at the end of the simulations were satisfactory, with the multiplication factors being effective close to 100 PCM of the values provided by the benchmarks, as expected for a validated library. The minimum distance between these values was 2 PCM and the maximum of 280 PCM. The final analysis demonstrates that the ENDF / B-VII library has validated nuclear data for the isotopes of interest and may be used in future thorium study group projects

  19. Calculation of the life-time of thermal neutrons in a heterogeneous moderator: graphite-cadmium. Experimental verification using the pulsed neutrons method; Calcul du temps de vie des neutrons thermiques dans un moderateur heterogene: graphite-cadmium. Verification experimentale par la methode des neutrons pulses

    Energy Technology Data Exchange (ETDEWEB)

    Jean, Lalande [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1964-07-01

    The heterogeneous medium is made up of an oblong assembly consisting 23 cm cells containing a cadmium bar having a diameter of 3.31 cm. The experimental value found for the lattice absorption v{sigma}a = 941 sec{sup -1} is in agreement with the value calculated from a one-group theory for one cell taking d = 2.55 {+-} 0.12 cm for the extrapolation distance in the cadmium rod. (author) [French] Le milieu heterogene est constitue par un assemblage parallelepipedique de cellules carrees de pas 23 cm contenant une barre de cadmium de diametre 3,31 cm. La valeur experimentale trouvee pour l'absorption du reseau v{sigma}a = 941 s{sup -1} concorde avec la valeur calculee par une theorie a un groupe sur une cellule en prenant comme distance d'extrapolation dans la barre de cadmium d = 2,55 {+-} 0,12 cm. (auteur)

  20. Closed Brayton cycle power conversion systems for nuclear reactors :

    Energy Technology Data Exchange (ETDEWEB)

    Wright, Steven A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Lipinski, Ronald J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Vernon, Milton E. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Sanchez, Travis [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2006-04-01

    This report describes the results of a Sandia National Laboratories internally funded research program to study the coupling of nuclear reactors to gas dynamic Brayton power conversion systems. The research focused on developing integrated dynamic system models, fabricating a 10-30 kWe closed loop Brayton cycle, and validating these models by operating the Brayton test-loop. The work tasks were performed in three major areas. First, the system equations and dynamic models for reactors and Closed Brayton Cycle (CBC) systems were developed and implemented in SIMULINKTM. Within this effort, both steady state and dynamic system models for all the components (turbines, compressors, reactors, ducting, alternators, heat exchangers, and space based radiators) were developed and assembled into complete systems for gas cooled reactors, liquid metal reactors, and electrically heated simulators. Various control modules that use proportional-integral-differential (PID) feedback loops for the reactor and the power-conversion shaft speed were also developed and implemented. The simulation code is called RPCSIM (Reactor Power and Control Simulator). In the second task an open cycle commercially available Capstone C30 micro-turbine power generator was modified to provide a small inexpensive closed Brayton cycle test loop called the Sandia Brayton test-Loop (SBL-30). The Capstone gas-turbine unit housing was modified to permit the attachment of an electrical heater and a water cooled chiller to form a closed loop. The Capstone turbine, compressor, and alternator were used without modification. The Capstone systems nominal operating point is 1150 K turbine inlet temperature at 96,000 rpm. The annular recuperator and portions of the Capstone control system (inverter) and starter system also were reused. The rotational speed of the turbo-machinery is controlled by adjusting the alternator load by using the electrical grid as the load bank. The SBL-30 test loop was operated at

  1. Natural cycle IVF with and without terminal HCG: learning from failed cycles.

    Science.gov (United States)

    Lenton, Elizabeth A

    2007-08-01

    Natural cycle IVF, without the use of LH down-regulation, is difficult because women start spontaneous LH surges at any time of the day and on any day of the week. This is not readily compatible with delivery of a routine IVF service and so historically the natural cycle has been modified by the use of human chorionic gonadotrophin (HCG) to make the natural cycle fit convenient clinical practice. This report re-evaluates data collected some years ago and seeks to determine whether the use of HCG is ultimately beneficial. Two large series of natural cycle IVF where only LH monitoring was performed (534 cycles) or where this was combined with HCG as necessary (241 cycles) were analysed. In essence, the use of HCG introduced as many problems as it overcame: there was no net benefit with respect to the number of eggs collected or clinical pregnancies generated. In fact there was an overall deterioration in all indices. The principle difficulties with natural cycle IVF are those associated with the prediction of follicle maturity and hence timing egg collection, and the conflict between costly and intrusively frequent monitoring with simpler but far less effective approaches.

  2. Dual Expander Cycle Rocket Engine with an Intermediate, Closed-cycle Heat Exchanger

    Science.gov (United States)

    Greene, William D. (Inventor)

    2008-01-01

    A dual expander cycle (DEC) rocket engine with an intermediate closed-cycle heat exchanger is provided. A conventional DEC rocket engine has a closed-cycle heat exchanger thermally coupled thereto. The heat exchanger utilizes heat extracted from the engine's fuel circuit to drive the engine's oxidizer turbomachinery.

  3. Ammonia-water Rankine cycle

    International Nuclear Information System (INIS)

    Bo Hanliang; Ma Changwen; Wu Shaorong

    1997-01-01

    On characteristics of heating source and cooling source in nuclear heating reactor cooperation, the authors advance a new kind of power cycle in which a multicomponent mixture as the work fluid, ammonia-water Rankine cycle, describe its running principle, and compare it with steam Rankine cycle in the same situation. The result is that: the new kind of power cycle, ammonia-water Rankine cycle has higher electricity efficiency; it suits for the situation of heating source and cooling source which offered by nuclear heating reactor cooperation. For low temperature heating source, it maybe has a widely application

  4. Study on the supercritical CO2 power cycles for landfill gas firing gas turbine bottoming cycle

    International Nuclear Information System (INIS)

    Kim, Min Seok; Ahn, Yoonhan; Kim, Beomjoo; Lee, Jeong Ik

    2016-01-01

    In this paper, a comparison of nine supercritical carbon dioxide (S-CO 2 ) bottoming power cycles in conjunction with a topping cycle of landfill gas (LFG) fired 5MWe gas turbine is presented. For the comparison purpose, a sensitivity study of the cycle design parameters for nine different cycles was conducted and each cycle thermodynamic performance is evaluated. In addition, the cycle performance evaluation dependency on the compressor inlet temperature variation is performed to investigate how S-CO 2 cycles sensitive to the heat sink temperature variation. Furthermore, the development of new S-CO 2 cycle layouts is reported and the suggested cycles' performances are compared to the existing cycle layouts. It was found that a recompression cycle is not suitable for the bottoming cycle application, but a partial heating cycle has relatively higher net produced work with a simple layout and small number of components. Although a dual heated and flow split cycle has the highest net produced work, it has disadvantages of having numerous components and complex process which requires more sophisticated operational strategies. This study identified that the recuperation process is much more important than the intercooling process to the S-CO 2 cycle design for increasing the thermal efficiency and the net produced work point of view. - Highlights: • Study of nine S-CO 2 power cycle layouts for a small scale landfill gas power generation application. • Development of new S-CO 2 cycle layouts. • Sensitivity analysis of S-CO 2 cycles to evaluate and compare nine cycles' performances.

  5. Optimization of Brayton cycles for low-to-moderate grade thermal energy sources

    International Nuclear Information System (INIS)

    Rovira, Antonio; Muñoz-Antón, Javier; Montes, María José; Martínez-Val, José María

    2013-01-01

    Future electricity generation will involve low or moderate temperature technologies. In such a scenario, optimisation of thermodynamic cycles will be a key task. This work presents a systematic analysis to find the operating regime where Brayton cycles reach the highest efficiency, using real substances and given heat source and sink temperatures. Several configurations using fluids close to its critical point at the compressor inlet are considered. Irreversibility sources are carefully analysed, as well as the type of working fluid. The analysis is performed by means of a theoretical approach to obtain some trends, which are afterwards validated with real gases. Results show that the efficiency and the specific work improve if the compressor inlet is close to the critical point. Furthermore, these cycles are less sensitive to pressure drops and politropic efficiencies than those working with ideal gases. The above features are more evident when the ratio of heat source and heat sink temperatures is low. The selection of the gas becomes a fundamental issue in this quest. Critical temperature should be close to ambient temperature, low critical pressure is advisable and the R/c p factor measured at the ideal gas condition should be low to further enhance the efficiency. - Highlights: • Performance analysis of Brayton cycles with the compressor inlet close to the critical point. • Cycles are not very sensitive to pressure drops and isentropic efficiencies of the compressor. • Gas selection becomes important, regarding the critical pressure and temperature as well as the kind of fluid. • R/c p factor measured at the ideal gas condition should be as low as possible

  6. Validation of the sterilization process for radiopharmaceuticals and materials with humid heat

    International Nuclear Information System (INIS)

    Robles, Anita; Moore, Mariel; Morote, Mario; Guevara, Buenaventura; Castro, Delcy; Paragulla, Wilson; Martinez, Ramos; Ocana, Elias; Novoa, Carlos

    2014-01-01

    A validation protocol has been designed and applied for the sterilization process of radiopharmaceuticals and materials, with humid heat for sodium pertechnetate Tc-99m injection solution (placebo) and materials, in compliance with good manufacturing practices for pharmaceutical products. The sterilization cycle set for each load is developed, according to the following parameters: 121 o C ± 1 o C (temperature), 15 ± 0.5 psi (pressure) and an exposure time of 20 and 15 minutes, respectively. The results in the penetration test with load, F0 values were higher than 20 minutes at 121 o C and for the biological challenge by biological indicators (Bacillus stearothermophilus) was negative in colder spots, in three consecutive runs. The sterilization process for each load and equipment has been validated to meet the established acceptance criteria. (authors).

  7. Effect of cycle coupling-configuration on energy cascade utilization for a new power and cooling cogeneration cycle

    International Nuclear Information System (INIS)

    Jing, Xuye; Zheng, Danxing

    2014-01-01

    Highlights: • A new power and cooling cogeneration cycle was proposed. • The thermophysical properties and the performance of the new cycle were calculated. • Different cycle coupling-configurations were analyzed. • The energy efficiency boosting mechanism of the new cycle was elucidated. - Abstract: To recover mid-low grade heat, a new power/cooling cogeneration cycle was proposed by combining the Kalina cycle and the double-effect ammonia–water absorption refrigeration (DAAR) cycle together, and the equivalent heat-to-power and exergy efficiencies of the cogeneration cycle reached 41.18% and 58.00%, respectively. To determine the effect of cycle coupling-configuration on energy cascade utilization for the new cycle, the cycle coupling-configuration of the Kalina and DAAR cycles were first analyzed, after which the cycle coupling-configuration of the new cycle was analyzed. Analysis results showed that the cycle coupling-configuration of the new cycle enhanced the energy cascade utilization. Furthermore, the energy efficiency boosting mechanism of the new cycle was elucidated

  8. Structurally optimized analogs of the retrograde trafficking inhibitor Retro-2cycl limit Leishmania infections.

    Science.gov (United States)

    Craig, Evan; Huyghues-Despointes, Charles-Eugene; Yu, Chun; Handy, Emma L; Sello, Jason K; Kima, Peter E

    2017-05-01

    In infected mammalian cells, Leishmania parasites reside within specialized compartments called parasitophorous vacuoles (LPVs). We have previously shown that Retro-2, a member of a novel class of small retrograde pathway inhibitors caused reduced LPV sizes and lower parasite numbers during experimental L. mexicana sp. infections. The purpose of this study was to determine if structural analogs of Retro-2cycl reported to have superior potency in the inhibition of retrograde pathway-dependent phenomena (i.e., polyomavirus cellular infection by polyomavrius and Shiga toxin trafficking in cells) are also more effective than the parent compound at controlling Leishmania infections. In addition to their effects on LPV development, we show that two optimized analogs of Retro-2cycl, DHQZ 36 and DHQZ 36.1 limit Leishmania amazonensis infection in macrophages at EC50 of 13.63+/-2.58μM and10.57+/-2.66μM, respectively, which is significantly lower than 40.15μM the EC50 of Retro-2cycl. In addition, these analogs caused a reversal in Leishmania induced suppression of IL-6 release by infected cells after LPS activation. Moreover, we show that in contrast to Retro-2cycl that is Leishmania static, the analogs can kill Leishmania parasites in axenic cultures, which is a desirable attribute for any drug to treat Leishmania infections. Together, these studies validate and extend the published structure-activity relationship analyses of Retro-2cycl.

  9. Structure and influence factors of fuel cycle costs of pebble bed HTRs with OTTO-fuel management

    Energy Technology Data Exchange (ETDEWEB)

    Jacke, S.

    1975-06-15

    The study in this paper can be divided into two parts. The first part deals with the analysis of the structure of the fuel cycle costs of today in 1974. A comparison is made between two pebble bed HTRs with OTTO-refueling-management (once-through) and a LWR of the type Biblis A. The two HTRs use different fuels: The one low-enriched Uranium (LOTTO), the other high-enriched Uranium and Thorium (TOTTO). The analysis of the structure of the fuel cycle costs consists of a discussion of the most important input parameters, and a comparison of each cost item. This study was made without adjustment of the core design to the changing market conditions. It is quite natural that an adaptation of the moderation ratio, of the conversion ratio, of the enrichment level, and of the burn-up may lower the fuel cycle costs. But the differences cannot be very important, and the results of this examination may remain valid, even on best adjustment conditions.

  10. Air bottoming cycle, an alternative to combined cycles. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Kaikko, J. [Royal Inst. of Tech., Stockholm (Sweden). Dept. of Energy Technology

    2002-02-01

    In this work, the idea of Air Bottoming Cycle (ABC) has been studied. The objectives for the work have been to establish an understanding of the concept for power and heat generation as well as to find - if possible - feasible concepts for future use in the Swedish energy system. Combined cycle in power generation is an established technology. In the conventional combined cycle, a gas turbine works as a topping cycle together with the steam (Rankine) bottoming cycle. In the ABC the steam bottoming cycle is replaced with a gas turbine (Brayton) bottoming cycle having air as a working fluid. The two gas turbines are thermally connected over a gas-to-gas heat exchanger. This concept promises savings in weight and cost, as well as operating benefits, compared to the Rankine bottoming technology. The ABC has been modelled using a heat balance program, and a parametric study for the concept optimisation as well as for off-design analysis has been performed. Performance of the ABC has been compared to other, established technologies. A preliminary economic evaluation has been made. As a result of the study, it is clarified that the Rankine bottoming cycle with steam remains superior to the ABC as regards electrical efficiency in the medium and large power scale. For small-scale applications (<10 MW{sub e}) where the thermodynamic advantage of the Rankine cycle is not dominating any longer and its economy is burdened by the heavy investment structure, the ABC becomes the better alternative for energy utilisation. A preliminary economic evaluation shows that (at energy prices autumn 2000) the ABC is at the same level as the comparable small-scale cogeneration installations. Due to high power-to-heat ratio however, higher electricity prices will favour the ABC. One interesting feature of the ABC is that about 50% of the dissipated low-value heat from the cycle is carried by clean (sterile) air at the temperature around 200 deg C. This air can be utilised for space heating or

  11. Very high cycle fatigue testing of concrete using ultrasonic cycling

    Energy Technology Data Exchange (ETDEWEB)

    Karr, Ulrike; Schuller, Reinhard; Fitzka, Michael; Mayer, Herwig [Univ. of Natural Resources and Life Sciences, Vienna (Austria). Inst. of Physics and Materials Science; Denk, Andreas; Strauss, Alfred [Univ. of Natural Resources and Life Sciences, Vienna (Austria)

    2017-06-01

    The ultrasonic fatigue testing method has been further developed to perform cyclic compression tests with concrete. Cylindrical specimens vibrate in resonance at a frequency of approximately 20 kHz with superimposed compressive static loads. The high testing frequency allows time-saving investigations in the very high cycle fatigue regime. Fatigue tests were carried out on ''Concrete 1'' (compressive strength f{sub c} = 80 MPa) and ''Concrete 2'' (f{sub c} = 107 MPa) under purely compressive loading conditions. Experiments at maximum compressive stresses of 0.44 f{sub c} (Concrete 1) and 0.38 f{sub c} (Concrete 2) delivered specimen failures above 109 cycles, indicating that no fatigue limit exists for concrete below one billion load cycles. Resonance frequency, power required to resonate the specimen and second order harmonics of the vibration are used to monitor fatigue damage in situ. Specimens were scanned by X-ray computed tomography prior to and after testing. Fatigue cracks were produced by ultrasonic cycling in the very high cycle fatigue regime at interfaces of grains as well as in cement. The possibilities as well as limitations of ultrasonic fatigue testing of concrete are discussed.

  12. International Business Cycle

    OpenAIRE

    Marek Lubiński

    2007-01-01

    Prime stylized facts of international business cycle theory refer to positive correlation in the cyclical components of important macroeconomic variables across countries. However a number of indicators of business cycle synchronization do not point to clear trends. It can be ascribed to the fact that different forces influence level of business cycle correlation. When investigating into the forces behind the commonness in aggregate fluctuations economic research seems to have pointed in two ...

  13. An optimization method for gas refrigeration cycle based on the combination of both thermodynamics and entransy theory

    International Nuclear Information System (INIS)

    Chen, Qun; Xu, Yun-Chao; Hao, Jun-Hong

    2014-01-01

    Highlights: • An optimization method for practical thermodynamic cycle is developed. • The entransy-based heat transfer analysis and thermodynamic analysis are combined. • Theoretical relation between system requirements and design parameters is derived. • The optimization problem can be converted into conditional extremum problem. • The proposed method provides several useful optimization criteria. - Abstract: A thermodynamic cycle usually consists of heat transfer processes in heat exchangers and heat-work conversion processes in compressors, expanders and/or turbines. This paper presents a new optimization method for effective improvement of thermodynamic cycle performance with the combination of entransy theory and thermodynamics. The heat transfer processes in a gas refrigeration cycle are analyzed by entransy theory and the heat-work conversion processes are analyzed by thermodynamics. The combination of these two analysis yields a mathematical relation directly connecting system requirements, e.g. cooling capacity rate and power consumption rate, with design parameters, e.g. heat transfer area of each heat exchanger and heat capacity rate of each working fluid, without introducing any intermediate variable. Based on this relation together with the conditional extremum method, we theoretically derive an optimization equation group. Simultaneously solving this equation group offers the optimal structural and operating parameters for every single gas refrigeration cycle and furthermore provides several useful optimization criteria for all the cycles. Finally, a practical gas refrigeration cycle is taken as an example to show the application and validity of the newly proposed optimization method

  14. KOH concentration effect on cycle life of nickel-hydrogen cells. III - Cycle life test

    Science.gov (United States)

    Lim, H. S.; Verzwyvelt, S. A.

    1988-01-01

    A cycle life test of Ni/H2 cells containing electrolytes of various KOH concentrations and a sintered type nickel electrode was carried out at 23 C using a 45 min accelerated low earth orbit (LEO) cycle regime at 80 percent depth of discharge. One of three cells containing 26 percent KOH has achieved over 28,000 cycles, and the other two 19,000 cycles, without a sign of failure. Two other cells containing 31 percent KOH electrolyte, which is the concentration presently used in aerospace cells, failed after 2,979 and 3,620 cycles. This result indicates that the cycle life of the present type of Ni/H2 cells may be extended by a factor of 5 to 10 simply by lowering the KOH concentration. Long cycle life of a Ni/H2 battery at high depth-of-discharge operation is desired, particularly for an LEO spacecraft application. Typically, battery life of about 30,000 cycles is required for a five year mission in an LEO. Such a cycle life with presently available cells can be assured only at a very low depth-of-discharge operation. Results of testing already show that the cycle life of an Ni/H2 cell is tremendously improved by simply using an electrolyte of low KOH concentration.

  15. Aproximación al estudio de las estrategias didácticas en ciencias experimentales en formación inicial del profesorado de Educación Secundaria: descripción de una experiencia

    Directory of Open Access Journals (Sweden)

    Natalia Jiménez-Tenorio

    2016-01-01

    Full Text Available Se fundamenta y describe una actividad orientada a la formación inicial de profesores de secundaria de especialidades de ciencias experimentales. La actividad está planteada como intento de aproximación al estudio de distintas estrategias didácticas, más o menos insertas dentro del marco socio-constructivista: “aprendizaje por descubrimiento”, “cambio conceptual”, “enseñanza por investigación entorno a problemas” y “enfoques CTS”. La actividad incluye una serie de estudios de caso (cuatro en total, uno para cada estrategia analizada consistente en supuestos de secuencias de actividades dirigidas a alumnos de educación secundaria obligatoria. Acompañando a los cuatro casos se proporciona un guión de análisis consistente en una serie de preguntas que los alumnos tienen que responder, como forma de orientar el trabajo y de articular el desarrollo de la actividad en su conjunto. La actividad fue ensayada con grupos de alumnos del MAES (Máster de Educación Secundaria de especialidades de “Física y Química” y de “Biología y geología”, y sus resultados expuestos en otro estudio publicado en paralelo a éste.

  16. Driving and engine cycles

    CERN Document Server

    Giakoumis, Evangelos G

    2017-01-01

    This book presents in detail the most important driving and engine cycles used for the certification and testing of new vehicles and engines around the world. It covers chassis and engine-dynamometer cycles for passenger cars, light-duty vans, heavy-duty engines, non-road engines and motorcycles, offering detailed historical information and critical review. The book also provides detailed examples from SI and diesel engines and vehicles operating during various cycles, with a focus on how the engine behaves during transients and how this is reflected in emitted pollutants, CO2 and after-treatment systems operation. It describes the measurement methods for the testing of new vehicles and essential information on the procedure for creating a driving cycle. Lastly, it presents detailed technical specifications on the most important chassis-dynamometer cycles around the world, together with a direct comparison of those cycles.

  17. Development of Demonstration Facility Design Technology for Advanced Nuclear Fuel Cycle Process

    International Nuclear Information System (INIS)

    Cho, Il Je; You, G. S.; Choung, W. M.

    2010-04-01

    The main objective of this R and D is to develop the PRIDE (PyRoprocess Integrated inactive DEmonstration) facility for engineering-scale inactive test using fresh uranium, and to establish the design requirements of the ESPF (Engineering Scale Pyroprocess Facility) for active demonstration of the pyroprocess. Pyroprocess technology, which is applicable to GEN-IV systems as one of the fuel cycle options, is a solution of the spent fuel accumulation problems. PRIDE Facility, pyroprocess mock-up facility, is the first facility that is operated in inert atmosphere in the country. By using the facility, the functional requirements and validity of pyroprocess technology and facility related to the advanced fuel cycle can be verified with a low cost. Then, PRIDE will contribute to evaluate the technology viability, proliferation resistance and possibility of commercialization of the pyroprocess technology. The PRIDE evaluation data, such as performance evaluation data of equipment and operation experiences, will be directly utilized for the design of ESPF

  18. Automation life-cycle cost model

    Science.gov (United States)

    Gathmann, Thomas P.; Reeves, Arlinda J.; Cline, Rick; Henrion, Max; Ruokangas, Corinne

    1992-01-01

    The problem domain being addressed by this contractual effort can be summarized by the following list: Automation and Robotics (A&R) technologies appear to be viable alternatives to current, manual operations; Life-cycle cost models are typically judged with suspicion due to implicit assumptions and little associated documentation; and Uncertainty is a reality for increasingly complex problems and few models explicitly account for its affect on the solution space. The objectives for this effort range from the near-term (1-2 years) to far-term (3-5 years). In the near-term, the envisioned capabilities of the modeling tool are annotated. In addition, a framework is defined and developed in the Decision Modelling System (DEMOS) environment. Our approach is summarized as follows: Assess desirable capabilities (structure into near- and far-term); Identify useful existing models/data; Identify parameters for utility analysis; Define tool framework; Encode scenario thread for model validation; and Provide transition path for tool development. This report contains all relevant, technical progress made on this contractual effort.

  19. Construction and Validation of the Marital Justice Scale

    Directory of Open Access Journals (Sweden)

    Majid Ghaffari

    2013-11-01

    Full Text Available The main purpose of this study was to construct and validate a scale for measuring marital justice. A sample of three hundred and four voluntary and unpaid married participants (194 females, 110 males, aged between 20 and 35 years old (29.01 ± 4.44 years, were selected randomly through multi-stage sampling in Isfahan, Iran; the participants included in this sample had preschool child/children, were all in the first decade of marriage, and had at least eight grades of education. All participants were asked to complete the Marital Justice Scale (MJS, the Revised Dyadic Adjustment Scale (R-DAS; Busby, Christensen, Crane, & Larson, 1995, and the Marital Conflict Questionnaire (MCQ; Sanai Zaker, 2000. The exploratory factor analysis extracted two factors labelled ‘Procedural/interactional justice’ (twelve items and ‘Distributive justice’ (eight items which accounted for 66.70% of the total variance. The convergent and discriminant validity of the 20-item MJS were supported by an expected pattern of correlations between the scale and the measures of marital quality and marital conflict. All correlation coefficients between the mean scores of the MJS and the scores of the RDAS and the MCQ were statistically significant. The obtained internal consistency was markedly high (Cronbach’s α = .97. The test-retest reliability of the MJS was .87. The results suggest that the MJS is a reliable and valid measure; however, further studies should be carried out in other countries, based on different age groups and socio-economic levels, various developmental stages of family life cycles, diverse cultures and sub-cultures, and according to gender difference so as to validate the MJS.

  20. The heat engine cycle, the heat removal cycle, and ergonomics of the control room displays

    International Nuclear Information System (INIS)

    Beltracchi, L.

    1986-01-01

    This paper discusses and illustrates the ergonomics of an integrated display, which will allow operators to monitor the heat engine cycle during normal operation of the plant, and the heat removal cycle during emergency operation of the plant. A computer-based iconic display is discussed as an overview to monitor these cycles. Specific emphasis is placed upon the process variables and process functions within each cycle, and the action of control systems and engineered safeguard systems within each cycle. This paper contains examples of display formats for the heat engine cycle and the heat removal cycle in a pressurized water reactor

  1. Construct Validity and Case Validity in Assessment

    Science.gov (United States)

    Teglasi, Hedwig; Nebbergall, Allison Joan; Newman, Daniel

    2012-01-01

    Clinical assessment relies on both "construct validity", which focuses on the accuracy of conclusions about a psychological phenomenon drawn from responses to a measure, and "case validity", which focuses on the synthesis of the full range of psychological phenomena pertaining to the concern or question at hand. Whereas construct validity is…

  2. Bicycle Trains, Cycling, and Physical Activity: A Pilot Cluster RCT.

    Science.gov (United States)

    Mendoza, Jason A; Haaland, Wren; Jacobs, Maya; Abbey-Lambertz, Mark; Miller, Josh; Salls, Deb; Todd, Winifred; Madding, Rachel; Ellis, Katherine; Kerr, Jacqueline

    2017-10-01

    Increasing children's cycling to school and physical activity are national health goals. The objective was to conduct an RCT of a bicycle train program to assess impact on students' school travel mode and moderate-to-vigorous physical activity (MVPA). Pilot cluster RCT with randomization at the school level and N=54 participants. Fourth-fifth graders from four public schools serving low-income families in Seattle, WA in 2014 with analyses in 2015-2016. All participants were provided and fitted with bicycles, safety equipment (helmets, locks, and lights), and a 2- to 3-hour bicycle safety course. The intervention was a bicycle train offered daily (i.e., students volunteered to cycle with study staff to and from school). Time 1 assessments occurred prior to randomization. Time 2 assessments occurred after 3-5 weeks of the intervention (i.e., during Weeks 4-6 of the intervention period). The primary outcome was the percentage of daily commutes to school by cycling measured by validated survey. MVPA, measured by accelerometry and GPS units and processed by machine learning algorithms, was a secondary outcome. For two separate adjusted repeated measures linear mixed effects models in which students (N=54) were nested within schools (N=4), intervention participants had: (1) an absolute increase in mean percentage of daily commutes by cycling of 44.9%, (95% CI=26.8, 63.0) and (2) an increase in mean MVPA of 21.6 minutes/day, (95% CI=8.7, 34.6) from Time 1 to Time 2 compared with controls. A pilot bicycle train intervention increased cycling to school and daily MVPA in the short term among diverse, inner-city elementary school students. The bicycle train intervention appears promising and warrants further experimental trials among large, diverse samples with longer follow-up. This study is registered at www.clinicaltrials.gov NCT02006186. Copyright © 2017 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

  3. Novel combined cycle configurations for propane pre-cooled mixed refrigerant (APCI) natural gas liquefaction cycle

    International Nuclear Information System (INIS)

    Mortazavi, Amir; Alabdulkarem, Abdullah; Hwang, Yunho; Radermacher, Reinhard

    2014-01-01

    Highlights: • 10 New LNG plants driver cycle enhancement configurations were developed. • All the 14 enhancement options design variables were optimized to demonstrate their energy saving potentials. • The best driver cycle enhancement option improved the driver cycle energy efficiency by 38%. • The effects of technological advancements on the performances of the enhancement options were studied. - Abstract: A significant amount of energy is required for natural gas liquefaction. Due to the production scale of LNG plants, they consume an intensive amount of energy. Consequently, any enhancement to the energy efficiency of LNG plants will result in a considerable reduction in natural gas consumption and CO 2 emission. Compressor drivers are the main energy consumer in the LNG plants. In this paper, 14 different driver cycle enhancement options were considered. A number of these options have not been proposed for the LNG plants. The new driver cycle development was performed by analyzing and optimizing the design variables of four conventional driver cycle enhancement options. The optimization results were used to develop more efficient cycles through mitigating the active constrains and driver cycle innovations. Based on the current available technologies five of our newly developed driver cycle configurations have higher efficiency than the most efficient existing conventional driver cycle. The best developed driver cycle enhancement option improved the base driver cycle energy efficiency by 38%. The effects of technological advancement on the performances of the all driver cycle enhancement options were also considered

  4. Validation of the thermal balance of Laguna Verde turbine under conditions of extended power increase

    International Nuclear Information System (INIS)

    Castaneda G, M. A.; Cruz B, H. J.; Mercado V, J. J.; Cardenas J, J. B.; Garcia de la C, F. M.

    2012-10-01

    The present work is a continuation of the task: Modeling of the vapor cycle of Laguna Verde with the PEPSE code to conditions of thermal power licensed at present (2027 MWt) in which the modeling of the vapor cycle of the nuclear power plant of Laguna Verde was realized with PEPSE code (Performance Evaluation of Power System Efficiencies). Once reached the conditions of nominal operation of extended power increase, operating both units to 2371 MWt; after the tests phase of starting-up and operation is necessary to carry out a verification of the proposed design of the vapor cycle for the new operation conditions. All this, having in consideration that the vapor cycle designer only knows the detail of the prospective performance of the main turbine, for all the other components (for example pumps, heat inter changers, valves, reactor, humidity separators and re-heaters, condensers, etc.) makes generic suppositions based on engineering judgment. This way carries out the calculations of thermal balance to determine the guaranteed gross power. The purpose of the present work is to comment the detail of the validation carried out of the specific thermal balance (thermal kit) of the nuclear power plant, making use of the design characteristics of the different components that conform the vapor cycle. (Author)

  5. Tritium Cycle Design for He-cooled Blankets for Demo

    International Nuclear Information System (INIS)

    Sedano, L. A.

    2007-01-01

    Final goal of COMPU task is to develop a reliable tritium Process Flow Diagram (PFD) modelling tool for DEMO tritium cycle. With this aim, the COMPU task is devoted to: (1) Review of existing available documentation related on configuration layouts, and systems and tritium control process key technologies. (2) To select those validated and considered relevant as basis for code development. (3) Implement results from (1), and (2) in the PFD TRICICLO. This fi rst deliverable focuses on item (1) and is conceived as a managerial tool to: (1) establish and discuss the correct inputs, (2) to identify existing lack of basic information and (3) to establish the general demands and characteristics for the development of an advanced PFD model. Thus, in order to discuss and determine the basic information required for future new developments of the task, this report presents a review of the documentation of: (1) The outline of total cycle and system configuration with the main tritium system design specifications. (2) The ultimate processing technologies with the associated design of their implementing units. (3) Key parameters needed to describe processes and modes of operation of the system units. (4) An overview of the existing models for cycle and units with a general analysis of their performances and limitations. Thus, this report is a direct review of the base information generated previously in the context of tasks of the EU FT Programmers (reported in EFDA Green Books) and available results in open fields literature provided by parallel Programmes abroad (JP, US, RF). (Author) 102 refs

  6. Tritium Cycle Design for He-cooled Blankets for Demo

    Energy Technology Data Exchange (ETDEWEB)

    Sedano, L. A.

    2007-09-27

    Final goal of COMPU task is to develop a reliable tritium Process Flow Diagram (PFD) modelling tool for DEMO tritium cycle. With this aim, the COMPU task is devoted to: (1) Review of existing available documentation related on configuration layouts, and systems and tritium control process key technologies. (2) To select those validated and considered relevant as basis for code development. (3) Implement results from (1), and (2) in the PFD TRICICLO. This fi rst deliverable focuses on item (1) and is conceived as a managerial tool to: (1) establish and discuss the correct inputs, (2) to identify existing lack of basic information and (3) to establish the general demands and characteristics for the development of an advanced PFD model. Thus, in order to discuss and determine the basic information required for future new developments of the task, this report presents a review of the documentation of: (1) The outline of total cycle and system configuration with the main tritium system design specifications. (2) The ultimate processing technologies with the associated design of their implementing units. (3) Key parameters needed to describe processes and modes of operation of the system units. (4) An overview of the existing models for cycle and units with a general analysis of their performances and limitations. Thus, this report is a direct review of the base information generated previously in the context of tasks of the EU FT Programmers (reported in EFDA Green Books) and available results in open fields literature provided by parallel Programmes abroad (JP, US, RF). (Author) 102 refs.

  7. Chords in longest cycles

    DEFF Research Database (Denmark)

    Thomassen, Carsten

    2017-01-01

    If a graph G is 3-connected and has minimum degree at least 4, then some longest cycle in G has a chord. If G is 2-connected and cubic, then every longest cycle in G has a chord.......If a graph G is 3-connected and has minimum degree at least 4, then some longest cycle in G has a chord. If G is 2-connected and cubic, then every longest cycle in G has a chord....

  8. Temporal fluxomics reveals oscillations in TCA cycle flux throughout the mammalian cell cycle.

    Science.gov (United States)

    Ahn, Eunyong; Kumar, Praveen; Mukha, Dzmitry; Tzur, Amit; Shlomi, Tomer

    2017-11-06

    Cellular metabolic demands change throughout the cell cycle. Nevertheless, a characterization of how metabolic fluxes adapt to the changing demands throughout the cell cycle is lacking. Here, we developed a temporal-fluxomics approach to derive a comprehensive and quantitative view of alterations in metabolic fluxes throughout the mammalian cell cycle. This is achieved by combining pulse-chase LC-MS-based isotope tracing in synchronized cell populations with computational deconvolution and metabolic flux modeling. We find that TCA cycle fluxes are rewired as cells progress through the cell cycle with complementary oscillations of glucose versus glutamine-derived fluxes: Oxidation of glucose-derived flux peaks in late G1 phase, while oxidative and reductive glutamine metabolism dominates S phase. These complementary flux oscillations maintain a constant production rate of reducing equivalents and oxidative phosphorylation flux throughout the cell cycle. The shift from glucose to glutamine oxidation in S phase plays an important role in cell cycle progression and cell proliferation. © 2017 The Authors. Published under the terms of the CC BY 4.0 license.

  9. Topography induced spatial variations in diurnal cycles of assimilation and latent heat of Mediterranean forest

    Science.gov (United States)

    van der Tol, C.; Dolman, A. J.; Waterloo, M. J.; Raspor, K.

    2007-02-01

    The aim of this study is to explain topography induced spatial variations in the diurnal cycles of assimilation and latent heat of Mediterranean forest. Spatial variations of the fluxes are caused by variations in weather conditions and in vegetation characteristics. Weather conditions reflect short-term effects of climate, whereas vegetation characteristics, through adaptation and acclimation, long-term effects of climate. In this study measurements of plant physiology and weather conditions are used to explain observed differences in the fluxes. A model is used to study which part of the differences in the fluxes is caused by weather conditions and which part by vegetation characteristics. Data were collected at four experimental sub-Mediterranean deciduous forest plots in a heterogeneous terrain with contrasting aspect, soil water availability, humidity and temperature. We used a sun-shade model to scale fluxes from leaf to canopy, and calculated the canopy energy balance. Parameter values were derived from measurements of light interception, leaf chamber photosynthesis, leaf nitrogen content and 13C isotope discrimination in leaf material. Leaf nitrogen content is a measure of photosynthetic capacity, and 13C isotope discrimination of water use efficiency. For validation, sap-flux based measurements of transpiration were used. The model predicted diurnal cycles of transpiration and stomatal conductance, both their magnitudes and differences in afternoon stomatal closure between slopes of different aspect within the confidence interval of the validation data. Weather conditions mainly responsible for the shape of the diurnal cycles, and vegetation parameters for the magnitude of the fluxes. Although the data do not allow for a quantification of the two effects, the differences in vegetation parameters and weather among the plots and the sensitivity of the fluxes to them suggest that the diurnal cycles were more strongly affected by spatial variations in

  10. Topography induced spatial variations in diurnal cycles of assimilation and latent heat of Mediterranean forest

    Directory of Open Access Journals (Sweden)

    C. van der Tol

    2007-01-01

    Full Text Available The aim of this study is to explain topography induced spatial variations in the diurnal cycles of assimilation and latent heat of Mediterranean forest. Spatial variations of the fluxes are caused by variations in weather conditions and in vegetation characteristics. Weather conditions reflect short-term effects of climate, whereas vegetation characteristics, through adaptation and acclimation, long-term effects of climate. In this study measurements of plant physiology and weather conditions are used to explain observed differences in the fluxes. A model is used to study which part of the differences in the fluxes is caused by weather conditions and which part by vegetation characteristics. Data were collected at four experimental sub-Mediterranean deciduous forest plots in a heterogeneous terrain with contrasting aspect, soil water availability, humidity and temperature. We used a sun-shade model to scale fluxes from leaf to canopy, and calculated the canopy energy balance. Parameter values were derived from measurements of light interception, leaf chamber photosynthesis, leaf nitrogen content and 13C isotope discrimination in leaf material. Leaf nitrogen content is a measure of photosynthetic capacity, and 13C isotope discrimination of water use efficiency. For validation, sap-flux based measurements of transpiration were used. The model predicted diurnal cycles of transpiration and stomatal conductance, both their magnitudes and differences in afternoon stomatal closure between slopes of different aspect within the confidence interval of the validation data. Weather conditions mainly responsible for the shape of the diurnal cycles, and vegetation parameters for the magnitude of the fluxes. Although the data do not allow for a quantification of the two effects, the differences in vegetation parameters and weather among the plots and the sensitivity of the fluxes to them suggest that the diurnal cycles were more strongly affected by spatial

  11. Experimental investigation of power peak in vicinity of WWER-440 control rod at end of fuel cycle

    International Nuclear Information System (INIS)

    Mikus, J.

    2004-01-01

    This paper presents some results of the axial power (fission density) distribution measurements carried out on the light-water, zero-power reactor LR-0 in a WWER-440 type core in vicinity of the WWER-440 control rod model at zero boron concentration in moderator, modelling the conditions at the end of the WWER-440 fuel cycle. Further information concerns the control rod model description, specification of the LR-0 core, fuel assemblies and measurement conditions. The aim of performed experiment is enlargement of the available power peaking database to enable the validation of the calculation codes by means of the measured data that correspond to the end of WWER-440 fuel cycle. (author)

  12. Alternative fuel cycles

    International Nuclear Information System (INIS)

    Penn, W.J.

    1979-05-01

    Uranium resource utilization and economic considerations provide incentives to study alternative fuel cycles as future options to the PHWR natural uranium cycle. Preliminary studies to define the most favourable alternatives and their possible introduction dates are discussed. The important and uncertain components which influence option selection are reviewed, including nuclear capacity growth, uranium availability and demand, economic potential, and required technological developments. Finally, a summary of Ontario Hydro's program to further assess cycle selection and define development needs is given. (auth)

  13. Global parameterization and validation of a two-leaf light use efficiency model for predicting gross primary production across FLUXNET sites: TL-LUE Parameterization and Validation

    Energy Technology Data Exchange (ETDEWEB)

    Zhou, Yanlian [Jiangsu Provincial Key Laboratory of Geographic Information Science and Technology, School of Geographic and Oceanographic Sciences, Nanjing University, Nanjing China; Joint Center for Global Change Studies, Beijing China; Wu, Xiaocui [International Institute for Earth System Sciences, Nanjing University, Nanjing China; Joint Center for Global Change Studies, Beijing China; Ju, Weimin [International Institute for Earth System Sciences, Nanjing University, Nanjing China; Jiangsu Center for Collaborative Innovation in Geographic Information Resource Development and Application, Nanjing China; Chen, Jing M. [International Institute for Earth System Sciences, Nanjing University, Nanjing China; Joint Center for Global Change Studies, Beijing China; Wang, Shaoqiang [Key Laboratory of Ecosystem Network Observation and Modeling, Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Science, Beijing China; Wang, Huimin [Key Laboratory of Ecosystem Network Observation and Modeling, Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Science, Beijing China; Yuan, Wenping [State Key Laboratory of Earth Surface Processes and Resource Ecology, Future Earth Research Institute, Beijing Normal University, Beijing China; Andrew Black, T. [Faculty of Land and Food Systems, University of British Columbia, Vancouver British Columbia Canada; Jassal, Rachhpal [Faculty of Land and Food Systems, University of British Columbia, Vancouver British Columbia Canada; Ibrom, Andreas [Department of Environmental Engineering, Technical University of Denmark (DTU), Kgs. Lyngby Denmark; Han, Shijie [Institute of Applied Ecology, Chinese Academy of Sciences, Shenyang China; Yan, Junhua [South China Botanical Garden, Chinese Academy of Sciences, Guangzhou China; Margolis, Hank [Centre for Forest Studies, Faculty of Forestry, Geography and Geomatics, Laval University, Quebec City Quebec Canada; Roupsard, Olivier [CIRAD-Persyst, UMR Ecologie Fonctionnelle and Biogéochimie des Sols et Agroécosystèmes, SupAgro-CIRAD-INRA-IRD, Montpellier France; CATIE (Tropical Agricultural Centre for Research and Higher Education), Turrialba Costa Rica; Li, Yingnian [Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining China; Zhao, Fenghua [Key Laboratory of Ecosystem Network Observation and Modeling, Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Science, Beijing China; Kiely, Gerard [Environmental Research Institute, Civil and Environmental Engineering Department, University College Cork, Cork Ireland; Starr, Gregory [Department of Biological Sciences, University of Alabama, Tuscaloosa Alabama USA; Pavelka, Marian [Laboratory of Plants Ecological Physiology, Institute of Systems Biology and Ecology AS CR, Prague Czech Republic; Montagnani, Leonardo [Forest Services, Autonomous Province of Bolzano, Bolzano Italy; Faculty of Sciences and Technology, Free University of Bolzano, Bolzano Italy; Wohlfahrt, Georg [Institute for Ecology, University of Innsbruck, Innsbruck Austria; European Academy of Bolzano, Bolzano Italy; D' Odorico, Petra [Grassland Sciences Group, Institute of Agricultural Sciences, ETH Zurich Switzerland; Cook, David [Atmospheric and Climate Research Program, Environmental Science Division, Argonne National Laboratory, Argonne Illinois USA; Arain, M. Altaf [McMaster Centre for Climate Change and School of Geography and Earth Sciences, McMaster University, Hamilton Ontario Canada; Bonal, Damien [INRA Nancy, UMR EEF, Champenoux France; Beringer, Jason [School of Earth and Environment, The University of Western Australia, Crawley Australia; Blanken, Peter D. [Department of Geography, University of Colorado Boulder, Boulder Colorado USA; Loubet, Benjamin [UMR ECOSYS, INRA, AgroParisTech, Université Paris-Saclay, Thiverval-Grignon France; Leclerc, Monique Y. [Department of Crop and Soil Sciences, College of Agricultural and Environmental Sciences, University of Georgia, Athens Georgia USA; Matteucci, Giorgio [Viea San Camillo Ed LellisViterbo, University of Tuscia, Viterbo Italy; Nagy, Zoltan [MTA-SZIE Plant Ecology Research Group, Szent Istvan University, Godollo Hungary; Olejnik, Janusz [Meteorology Department, Poznan University of Life Sciences, Poznan Poland; Department of Matter and Energy Fluxes, Global Change Research Center, Brno Czech Republic; Paw U, Kyaw Tha [Department of Land, Air and Water Resources, University of California, Davis California USA; Joint Program on the Science and Policy of Global Change, Massachusetts Institute of Technology, Cambridge USA; Varlagin, Andrej [A.N. Severtsov Institute of Ecology and Evolution, Russian Academy of Sciences, Moscow Russia

    2016-04-01

    We present the first extended validation of satellitemicrowave (MW) liquidwater path (LWP) for low nonprecipitating clouds, from four operational sensors, against ship-borne observations from a three-channel MW radiometer collected along ship transects over the northeast Pacific during May–August 2013. Satellite MW retrievals have an overall correlation of 0.84 with ship observations and a bias of 9.3 g/m2. The bias for broken cloud scenes increases linearly with water vapor path and remains below 17.7 g/m2. In contrast, satelliteMWLWP is unbiased in overcast scenes with correlations up to 0.91, demonstrating that the retrievals are accurate and reliable under these conditions. Satellite MW retrievals produce a diurnal cycle amplitude consistent with ship-based observations (33 g/m2). Observations taken aboard extended ship cruises to evaluate not only satellite MW LWP but also LWP derived from visible/infrared sensors offer a new way to validate this important property over vast oceanic regions.

  14. Advanced power cycling test for power module with on-line on-state VCE measurement

    DEFF Research Database (Denmark)

    Choi, Ui-min; Trintis, Ionut; Blaabjerg, Frede

    2015-01-01

    module. The proposed concept can perform various stress conditions which is valid in a real mission profile and it is using a real power converter application with small loss. The concept of the proposed test setup is first presented. Then, the on-line on-state collector-emitter voltage VCE measurement......Recent research has made an effort to improve the reliability of power electronic systems to comply with more stringent constraints on cost, safety, predicted lifetime and availability in many applications. For this, studies about failure mechanisms of power electronic components and lifetime...... estimation of power semiconductor devices and capacitors have been done. Accelerated power cycling test is one of the common tests to assess the power device module and develop the lifetime model considering the physics of failure. In this paper, a new advanced power cycling test setup is proposed for power...

  15. Performance Analysis of Permanent Magnet Motors for Electric Vehicles (EV Traction Considering Driving Cycles

    Directory of Open Access Journals (Sweden)

    Thanh Anh Huynh

    2018-05-01

    Full Text Available This paper evaluates the electromagnetic and thermal performance of several traction motors for electric vehicles (EVs. Two different driving cycles are employed for the evaluation of the motors, one for urban and the other for highway driving. The electromagnetic performance to be assessed includes maximum motor torque output for vehicle acceleration and the flux weakening capability for wide operating range under current and voltage limits. Thermal analysis is performed to evaluate the health status of the magnets and windings for the prescribed driving cycles. Two types of traction motors are investigated: two interior permanent magnet motors and one permanent magnet-assisted synchronous reluctance motor. The analysis results demonstrate the benefits and disadvantages of these motors for EV traction and provide suggestions for traction motor design. Finally, experiments are conducted to validate the analysis.

  16. Educational Business Cycles

    DEFF Research Database (Denmark)

    Tepe, Markus; Vanhuysse, Pieter

    Strong institutional constraints and better-informed voters may lead re-election seeking incumbents to shift the use of political business cycle mechanisms away from monetary and fiscal policy towards other policy domains that are more easily manipulable, targetable, and timeable. We investigate...... teacher employment patterns at the state level in Germany and find strong evidence of cycling mechanisms, in the form of electioneering and honeymooning. Against a backdrop of a continuously shrinking total teachers' pool, German state-level incumbents accelerate the hiring of new teachers during election...... periods and partly reverse this during politically safer points in the electoral cycle. Cycles are mediated by issue salience: heightened attention to German public schooling after the notorious PISA-2000 tests further strengthens the manipulation of new teacher hiring for electoral purposes....

  17. Educational Business Cycles

    DEFF Research Database (Denmark)

    Tepe, Markus; Vanhuysse, Pieter

    2009-01-01

    Strong institutional constraints and better-informed voters may lead re-election seeking incumbents to shift the use of political business cycle mechanisms away from monetary and fiscal policy towards other policy domains that are more easily manipulable, targetable, and timeable. We investigate...... teacher employment patterns at the state level in Germany and find strong evidence of cycling mechanisms, in the form of electioneering and honeymooning. Against a backdrop of a continuously shrinking total teachers' pool, German state-level incumbents accelerate the hiring of new teachers during election...... periods and partly reverse this during politically safer points in the electoral cycle. Cycles are mediated by issue salience: heightened attention to German public schooling after the notorious PISA-2000 tests further strengthens the manipulation of new teacher hiring for electoral purposes....

  18. Dynamic tritium inventory of a NET/ITER fuel cycle with lithium salt solution blanket

    International Nuclear Information System (INIS)

    Spannagel, G.; Gierszewski, P.

    1991-01-01

    At the Karlsruhe Nuclear Research Center (KfK) a flexible tool is being developed to simulate the dynamics of tritium inventories. This tool can be applied to any tritium handling system, especially to the fuel cycle components of future nuclear fusion devices. This instrument of simulation will be validated in equipment to be operated at the Karlsruhe Tritium Laboratory. In this study tritium inventories in a NET/ITER type fuel cycle involving a lithium salt solution blanket are investigated. The salt solution blanket serves as an example because it offers technological properties which are attractive in modeling the process; the example does not impair the general validity of the tool. Usually, the operation strategy of complex structures will deteriorate due to failures of the subsystems involved. These failures together with the reduced availability ensuing from them will be simulated. The example of this study is restricted to reduced availabilities of two subsystems, namely the reactor and the tritium recovery system. For these subsystems the influence of statistically varying intervals of operation is considered. Strategies we selected which are representative of expected modes of operation. In the design of a fuel cycle, care will be taken that prescribed availabilities of the subsystems can be achieved; however, the description of reactor operation is a complex task since operation breaks down into several campaigns for which rules have been specified which enable determination of whether a campaign has been successful and can be stopped. Thus, it is difficult to predict the overall behavior prior to a simulation which includes stochastic elements. Using the example mentioned above the capabilities of the tool will be illustrated; besides the presentation of results of inventory simulation, the applicability of these data will be discussed. (orig.)

  19. Some experiments on the high-low transition of quartz; Recherches experimentales sur une transformation du quartz

    Energy Technology Data Exchange (ETDEWEB)

    Mayer, G. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1959-12-15

    , nous avons rassemble un grand nombre de resultats numeriques relatifs aux proprietes elastiques, piezoelectriques et optiques du quartz. Certains ont ete collectes dans la litterature; d'autres ont ete obtenus par nous a l'aide de methodes experimentales que nous decrivons, de facon a pouvoir presenter un tableau complet de l'evolution de ces constantes dans un domaine de temperature entourant largement le point de transformation {alpha} - {beta} situe a 574 deg. C. De nouveaux phenomenes ont ete observes au cours de ces mesures. Dans la troisieme partie, nous montrons qu'une meme fonction de la temperature decrit l'evolution de la constante piezoelectrique et de la constante elastique qui s'annulent en phase {beta}. Une seule autre fonction suffit a decrire correctement l'evolution de toutes les autres constantes etudiees, depuis leur valeur en phase {alpha} jusqu'a leur valeur en phase {beta}. A l'aide d'hypotheses sur la nature de l'entropie de transformation, nous essayons enfin d'expliquer la forme de ces fonctions. (auteur)

  20. Termination of cycle rewriting

    NARCIS (Netherlands)

    Zantema, H.; König, B.; Bruggink, H.J.S.; Dowek, G.

    2014-01-01

    String rewriting can not only be applied on strings, but also on cycles and even on general graphs. In this paper we investigate termination of string rewriting applied on cycles, shortly denoted as cycle rewriting, which is a strictly stronger requirement than termination on strings. Most

  1. Cure Cycle Design Methodology for Fabricating Reactive Resin Matrix Fiber Reinforced Composites: A Protocol for Producing Void-free Quality Laminates

    Science.gov (United States)

    Hou, Tan-Hung

    2014-01-01

    For the fabrication of resin matrix fiber reinforced composite laminates, a workable cure cycle (i.e., temperature and pressure profiles as a function of processing time) is needed and is critical for achieving void-free laminate consolidation. Design of such a cure cycle is not trivial, especially when dealing with reactive matrix resins. An empirical "trial and error" approach has been used as common practice in the composite industry. Such an approach is not only costly, but also ineffective at establishing the optimal processing conditions for a specific resin/fiber composite system. In this report, a rational "processing science" based approach is established, and a universal cure cycle design protocol is proposed. Following this protocol, a workable and optimal cure cycle can be readily and rationally designed for most reactive resin systems in a cost effective way. This design protocol has been validated through experimental studies of several reactive polyimide composites for a wide spectrum of usage that has been documented in the previous publications.

  2. The Nuclear Fuel Cycle

    International Nuclear Information System (INIS)

    2011-08-01

    This brochure describes the nuclear fuel cycle, which is an industrial process involving various activities to produce electricity from uranium in nuclear power reactors. The cycle starts with the mining of uranium and ends with the disposal of nuclear waste. The raw material for today's nuclear fuel is uranium. It must be processed through a series of steps to produce an efficient fuel for generating electricity. Used fuel also needs to be taken care of for reuse and disposal. The nuclear fuel cycle includes the 'front end', i.e. preparation of the fuel, the 'service period' in which fuel is used during reactor operation to generate electricity, and the 'back end', i.e. the safe management of spent nuclear fuel including reprocessing and reuse and disposal. If spent fuel is not reprocessed, the fuel cycle is referred to as an 'open' or 'once-through' fuel cycle; if spent fuel is reprocessed, and partly reused, it is referred to as a 'closed' nuclear fuel cycle.

  3. Can cycling safety be improved by opening all unidirectional cycle paths for cycle traffic in both directions? A theoretical examination of available literature and data.

    Science.gov (United States)

    Methorst, Rob; Schepers, Paul; Kamminga, Jaap; Zeegers, Theo; Fishman, Elliot

    2017-08-01

    Many studies have found bicycle-motor vehicle crashes to be more likely on bidirectional cycle paths than on unidirectional cycle paths because drivers do not expect cyclists riding at the right side of the road. In this paper we discuss the hypothesis that opening all unidirectional cycle paths for cycle traffic in both directions prevent this lack of expectancy and accordingly improves cycling safety. A new national standard requires careful consideration because a reversal is difficult once cyclists are used to their new freedom of route choice. We therefore explored the hypothesis using available data, research, and theories. The results show that of the length of cycle paths along distributor roads in the Netherlands, 72% is bidirectional. If drivers would become used to cyclists riding at the left side of the road, this result raises the question of why bidirectional cycle paths in the Netherlands still have a poor safety record compared to unidirectional cycle paths. Moreover, our exploration suggested that bidirectional cycle paths have additional safety problems. It increases the complexity of unsignalized intersections because drivers have to scan more directions in a short period of time. Moreover, there are some indications that the likelihood of frontal crashes between cyclists increases. We reject the hypothesis that opening all unidirectional cycle paths for cycle traffic in both directions will improve cycle safety. We recommend more attention for mitigating measures given the widespread application of bidirectional cycle paths in the Netherlands. Copyright © 2016 Elsevier Ltd. All rights reserved.

  4. Development of turbine cycle performance analyzer using intelligent data mining

    Energy Technology Data Exchange (ETDEWEB)

    Heo, Gyun Young

    2004-02-15

    In recent year, the performance enhancement of turbine cycle in nuclear power plants is being highlighted because of worldwide deregulation environment. Especially the first target of operating plants became the reduction of operating cost to compete other power plants. It is known that overhaul interval is closely related to operating cost Author identified that the rapid and reliable performance tests, analysis, and diagnosis play an important role in the control of overhaul interval through field investigation. First the technical road map was proposed to clearly set up the objectives. The controversial issues were summarized into data gathering, analysis tool, and diagnosis method. Author proposed the integrated solution on the basis of intelligent data mining techniques. For the reliable data gathering, the state analyzer composed of statistical regression, wavelet analysis, and neural network was developed. The role of the state analyzer is to estimate unmeasured data and to increase the reliability of the collected data. For the advanced performance analysis, performance analysis toolbox was developed. The purpose of this tool makes analysis process easier and more accurate by providing three novel heat balance diagrams. This tool includes the state analyzer and turbine cycle simulation code. In diagnosis module, the probabilistic technique based on Bayesian network model and the deterministic technique based on algebraical model are provided together. It compromises the uncertainty in diagnosis process and the pin-point capability. All the modules were validated by simulated data as well as actual test data, and some modules are used as industrial applications. We have a lot of thing to be improved in turbine cycle in order to increase plant availability. This study was accomplished to remind the concern about the importance of turbine cycle and to propose the solutions on the basis of academic as well as industrial needs.

  5. Development of turbine cycle performance analyzer using intelligent data mining

    International Nuclear Information System (INIS)

    Heo, Gyun Young

    2004-02-01

    In recent year, the performance enhancement of turbine cycle in nuclear power plants is being highlighted because of worldwide deregulation environment. Especially the first target of operating plants became the reduction of operating cost to compete other power plants. It is known that overhaul interval is closely related to operating cost Author identified that the rapid and reliable performance tests, analysis, and diagnosis play an important role in the control of overhaul interval through field investigation. First the technical road map was proposed to clearly set up the objectives. The controversial issues were summarized into data gathering, analysis tool, and diagnosis method. Author proposed the integrated solution on the basis of intelligent data mining techniques. For the reliable data gathering, the state analyzer composed of statistical regression, wavelet analysis, and neural network was developed. The role of the state analyzer is to estimate unmeasured data and to increase the reliability of the collected data. For the advanced performance analysis, performance analysis toolbox was developed. The purpose of this tool makes analysis process easier and more accurate by providing three novel heat balance diagrams. This tool includes the state analyzer and turbine cycle simulation code. In diagnosis module, the probabilistic technique based on Bayesian network model and the deterministic technique based on algebraical model are provided together. It compromises the uncertainty in diagnosis process and the pin-point capability. All the modules were validated by simulated data as well as actual test data, and some modules are used as industrial applications. We have a lot of thing to be improved in turbine cycle in order to increase plant availability. This study was accomplished to remind the concern about the importance of turbine cycle and to propose the solutions on the basis of academic as well as industrial needs

  6. Proteomes of the Female Genital Tract During the Oestrous Cycle.

    Science.gov (United States)

    Soleilhavoup, Clement; Riou, Cindy; Tsikis, Guillaume; Labas, Valerie; Harichaux, Gregoire; Kohnke, Philippa; Reynaud, Karine; de Graaf, Simon P; Gerard, Nadine; Druart, Xavier

    2016-01-01

    The female genital tract includes several anatomical regions whose luminal fluids successively interact with gametes and embryos and are involved in the fertilisation and development processes. The luminal fluids from the inner cervix, the uterus and the oviduct were collected along the oestrous cycle at oestrus (Day 0 of the cycle) and during the luteal phase (Day 10) from adult cyclic ewes. The proteomes were assessed by GeLC-MS/MS and quantified by spectral counting. A set of 940 proteins were identified including 291 proteins differentially present along the cycle in one or several regions. The global analysis of the fluid proteomes revealed a general pattern of endocrine regulation of the tract, with the cervix and the oviduct showing an increased differential proteins abundance mainly at oestrus while the uterus showed an increased abundance mainly during the luteal phase. The proteins more abundant at oestrus included several families such as the heat shock proteins (HSP), the mucins, the complement cascade proteins and several redox enzymes. Other proteins known for their interaction with gametes such as oviductin (OVGP), osteopontin, HSPA8, and the spermadhesin AWN were also overexpressed at oestrus. The proteins more abundant during the luteal phase were associated with the immune system such as ceruloplasmin, lactoferrin, DMBT1, or PIGR, and also with tissue remodeling such as galectin 3 binding protein, alkaline phosphatase, CD9, or fibulin. Several proteins differentially abundant between estrus and the luteal phase, such as myosin 9 and fibronectin, were also validated by immunohistochemistry. The potential roles in sperm transit and uterine receptivity of the proteins differentially regulated along the cycle in the female genital tract are discussed. © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

  7. An Inquiry into the Life Cycle of Systems of Inner Walls: Comparison of Masonry and Drywall

    Directory of Open Access Journals (Sweden)

    Karina Condeixa

    2015-06-01

    Full Text Available Life Cycle Assessment is a methodology that investigates impacts linked to a product or service during its entire life cycle. Life Cycle Assessment studies investigate processes and sub-processes in a fragmented way to ascertain their inputs, outputs and emissions and get an overview of the generating sources of their environmental loads. The lifecycle concept involves all direct and indirect processes of the studied object. This article aims to model the material flows in the masonry and drywall systems and internal walls in a Brazilian scenario, and calculate the climate change impacts generated by the transport of the component materials of the systems. Internal walls of a residential dwelling in Rio de Janeiro are analyzed from a qualitative inventory of all life cycles with an analysis of material flows, based on technical and academic literature. All Life Cycle Impact Assessment of the systems is carried out with international data from the database, and using the IPCC2013 method for climate change impacts. This study disregards the refurbishment and possible extensions within the use phase. Thus, the inventory identifies weaknesses of the systems while the impact assessment validates the results. This study allows us a complete understanding about the inner walls systems in the Brazilian scenario, evidencing its main weaknesses and subsidizes decision-making for the industry and for planning of the new buildings.

  8. Nuclear Fuel Cycle Information System. A directory of nuclear fuel cycle facilities. 2009 ed

    International Nuclear Information System (INIS)

    2009-04-01

    The Nuclear Fuel Cycle Information System (NFCIS) is an international directory of civilian nuclear fuel cycle facilities, published online as part of the Integrated Nuclear Fuel Cycle Information System (iNFCIS: http://www-nfcis.iaea.org/). This is the fourth hardcopy publication in almost 30 years and it represents a snapshot of the NFCIS database as of the end of 2008. Together with the attached CD-ROM, it provides information on 650 civilian nuclear fuel cycle facilities in 53 countries, thus helping to improve the transparency of global nuclear fuel cycle activities

  9. Ideal cycle analysis of a regenerative pulse detonation engine for power production

    Science.gov (United States)

    Bellini, Rafaela

    can be obtained as a function of fuel-oxidizer ratio. The Humphrey and ZND cycles are studied in comparison with the Brayton cycle for different fuel-air mixtures such as methane, propane and hydrogen. The validity and limitations of the ZND and Humphrey cycles related to the detonation process are discussed and the criteria for the selection of the best model for the PDE cycle are explained. It is seen that the ZND cycle is a more appropriate representation of the PDE cycle. Next, the thermal and electrical power generation efficiencies for the PDE are compared with those of the deflagration based Brayton cycle. While the Brayton cycle shows an efficiency of 0 at a compressor pressure ratio of 1, the thermal efficiency for the ZND cycle starts out at 42% for hydrogen--air and then climbs to a peak of 66% at a compression ratio of 7 before falling slowly for higher compression ratios. The Brayton cycle efficiency rises above the PDEs for compression ratios above 23. This finding supports the theoretical advantage of PDEs over the gas turbines because PDEs only require a fan or only a few compressor stages, thereby eliminating the need for heavy compressor machinery, making the PDEs less complex and therefore more cost effective than other engines. Lastly, a regeneration study is presented to analyze how the use of exhaust gases can improve the performance of the system. The thermal efficiencies for the regenerative ZND cycle are compared with the efficiencies for the non--regenerative cycle. For a hydrogen--air mixture the thermal efficiency increases from 52%, for a cycle without regeneration, to 78%, for the regenerative cycle. The efficiency is compared with the Carnot efficiency of 84% which is the maximum possible theoretical efficiency of the cycle. When compared to the Brayton cycle thermal efficiencies, the regenerative cycle shows efficiencies that are always higher for the pressure ratio studied of 5 ≤ pic ≤ 25, where pi c the compressor pressure ratio

  10. Dielectric barrier discharge-based plasma actuator operation in artificial atmospheres for validation of modeling and simulation

    Energy Technology Data Exchange (ETDEWEB)

    Mangina, R. S.; Enloe, C. L.; Font, G. I. [Department of Physics, United States Air Force Academy, Colorado 80840 (United States)

    2015-11-15

    We present an experimental case study of time-resolved force production by an aerodynamic plasma actuator immersed in various mixtures of electropositive (N{sub 2}) and electronegative gases (O{sub 2} and SF{sub 6}) at atmospheric pressure using a fixed AC high-voltage input of 16 kV peak amplitude at 200 Hz frequency. We have observed distinct changes in the discharge structures during both negative- and positive-going voltage half-cycles, with corresponding variations in the actuator's force production: a ratio of 4:1 in the impulse produced by the negative-going half-cycle of the discharge among the various gas mixtures we explored, 2:1 in the impulse produced by the positive-going half-cycle, and cases in which the negative-going half-cycle dominates force production (by a ratio of 1.5:1), where the half-cycles produce identical force levels, and where the positive-going half cycle dominates (by a ratio of 1:5). We also present time-resolved experimental evidence for the first time that shows electrons do play a significant role in the momentum coupling to surrounding neutrals during the negative going voltage half-cycle of the N{sub 2} discharge. We show that there is sufficient macroscopic variation in the plasma that the predictions of numerical models at the microscopic level can be validated even though the plasma itself cannot be measured directly on those spatial and temporal scales.

  11. Operation of Nuclear Fuel Based on Reprocessed Uranium for VVER-type Reactors in Competitive Nuclear Fuel Cycles

    Energy Technology Data Exchange (ETDEWEB)

    Troyanov, V.; Molchanov, V.; Tuzov, A. [TVEL Corporation, 49 Kashirskoe shosse, Moscow 115409 (Russian Federation); Semchenkov, Yu.; Lizorkin, M. [RRC ' Kurchatov Institute' (Russian Federation); Vasilchenko, I.; Lushin, V. [OKB ' Gidropress' (Russian Federation)

    2009-06-15

    Current nuclear fuel cycle of Russian nuclear power involves reprocessed low-enriched uranium in nuclear fuel production for some NPP units with VVER-type LWR. This paper discusses design and performance characteristics of commercial nuclear fuel based on natural and reprocessed uranium. It presents the review of results of commercial operation of nuclear fuel based on reprocessed uranium on Russian NPPs-unit No.2 of Kola NPP and unit No.2 of Kalinin NPP. The results of calculation and experimental validation of safe fuel operation including necessary isotope composition conformed to regulation requirements and results of pilot fuel operation are also considered. Meeting the customer requirements the possibility of high burn-up achieving was demonstrated. In addition the paper compares the characteristics of nuclear fuel cycles with maximum length based on reprocessed and natural uranium considering relevant 5% enrichment limitation and necessity of {sup 236}U compensation. The expedience of uranium-235 enrichment increasing over 5% is discussed with the aim to implement longer fuel cycles. (authors)

  12. Validation of X1 motorcycle model in industrial plant layout by using WITNESSTM simulation software

    Science.gov (United States)

    Hamzas, M. F. M. A.; Bareduan, S. A.; Zakaria, M. Z.; Tan, W. J.; Zairi, S.

    2017-09-01

    This paper demonstrates a case study on simulation, modelling and analysis for X1 Motorcycles Model. In this research, a motorcycle assembly plant has been selected as a main place of research study. Simulation techniques by using Witness software were applied to evaluate the performance of the existing manufacturing system. The main objective is to validate the data and find out the significant impact on the overall performance of the system for future improvement. The process of validation starts when the layout of the assembly line was identified. All components are evaluated to validate whether the data is significance for future improvement. Machine and labor statistics are among the parameters that were evaluated for process improvement. Average total cycle time for given workstations is used as criterion for comparison of possible variants. From the simulation process, the data used are appropriate and meet the criteria for two-sided assembly line problems.

  13. CYGNSS Surface Wind Validation and Characteristics in the Maritime Continent

    Science.gov (United States)

    Asharaf, S.; Waliser, D. E.; Zhang, C.; Wandala, A.

    2017-12-01

    Surface wind over tropical oceans plays a crucial role in many local/regional weather and climate processes and helps to shape the global climate system. However, there is a lack of consistent high quality observations for surface winds. The newly launched NASA Cyclone Global Navigation Satellite System (CYGNSS) mission provides near surface wind speed over the tropical ocean with sampling that accounts for the diurnal cycle. In the early phase of the mission, validation is a critical task, and over-ocean validation is typically challenging due to a lack of robust validation resources that a cover a variety of environmental conditions. In addition, it can also be challenging to obtain in-situ observation resources and also to extract co-located CYGNSS records for some of the more scientifically interesting regions, such as the Maritime Continent (MC). The MC is regarded as a key tropical driver for the mean global circulation as well as important large-scale circulation variability such as the Madian-Julian Oscillation (MJO). The focus of this project and analysis is to take advantage of local in-situ resources from the MC regions (e.g. volunteer shipping, marine buoys, and the Year of Maritime Continent (YMC) campaign) to quantitatively characterize and validate the CYGNSS derived winds in the MC region and in turn work to unravel the complex multi-scale interactions between the MJO and MC. This presentation will show preliminary results of a comparison between the CYGNSS and the in-situ surface wind measurements focusing on the MC region. Details about the validation methods, uncertainties, and planned work will be discussed in this presentation.

  14. Entrepreneurship and the business cycle

    NARCIS (Netherlands)

    Koellinger, Philipp D.; Thurik, A. Roy

    2012-01-01

    We find new empirical regularities in the business cycle in a cross-country panel of 22 OECD countries for the period 1972 to 2007; entrepreneurship Granger-causes the cycles of the world economy. Furthermore, the entrepreneurial cycle is positively affected by the national unemployment cycle. We

  15. Continuation of connecting orbits in 3d-ODEs. (ii) cycle-to-cycle connections.

    NARCIS (Netherlands)

    Doedel, E.J.; Kooi, B.W.; van Voorn, G.A.K.; Kuznetzov, Y.A.

    2009-01-01

    In Part I of this paper we have discussed new methods for the numerical continuation of point-to-cycle connecting orbits in three-dimensional autonomous ODE's using projection boundary conditions. In this second part we extend the method to the numerical continuation of cycle-to-cycle connecting

  16. A Framework for Performing Verification and Validation in Reuse Based Software Engineering

    Science.gov (United States)

    Addy, Edward A.

    1997-01-01

    Verification and Validation (V&V) is currently performed during application development for many systems, especially safety-critical and mission- critical systems. The V&V process is intended to discover errors, especially errors related to critical processing, as early as possible during the development process. The system application provides the context under which the software artifacts are validated. This paper describes a framework that extends V&V from an individual application system to a product line of systems that are developed within an architecture-based software engineering environment. This framework includes the activities of traditional application-level V&V, and extends these activities into domain engineering and into the transition between domain engineering and application engineering. The framework includes descriptions of the types of activities to be performed during each of the life-cycle phases, and provides motivation for the activities.

  17. An approach for assessing development and deployment risks in the DOE fuel cycle options evaluation and screening study - 5267

    International Nuclear Information System (INIS)

    Gehin, J.C.; Worrall, A.; Oakley, B.; Jenni, K.; Taiwo, T.; Wigeland, R.

    2015-01-01

    One of the key objectives of the U.S. Department of Energy (DOE) Nuclear Energy Research/development road-map is the development of sustainable nuclear fuel cycles that can improve natural resource utilization and provide solutions to the management of nuclear wastes. Recently, an evaluation and screening (ES) of fuel cycle systems has been conducted to identify those options that provide the best opportunities for obtaining such improvements and also to identify the required research and development activities that can support the development of advanced fuel cycle options. In order to evaluate and screen fuel cycle systems in the ES study, nine criteria were used including Development and Deployment Risk (DDR). More specifically, this criterion was represented by the following metrics: Development time, development cost, deployment cost from prototypic validation to first-of-a-kind commercial, compatibility with the existing nuclear fuel cycle infrastructure, existence of regulations for the fuel cycle and familiarity with licensing, and existence of market incentives and/or barriers to commercial implementation of fuel cycle processes. Given the comprehensive nature of the study, a systematic approach was needed to determine metric data for the DDR criterion. As would be expected, the Evaluation Group representing the once-through use of uranium in thermal reactors is always the highest ranked fuel cycle Evaluation Group for this DDR criterion. Evaluation Groups that consist of once-through fuel cycles that use existing reactor types are consistently ranked very high. The highest ranked limited and continuous recycle fuel cycle Evaluation Groups are those that recycle Pu in thermal reactors. The lowest ranked fuel cycles are predominately continuous recycle single stage and multi-stage fuel cycles that involve TRU and/or U 233 recycle. (authors)

  18. New Adsorption Cycles for Carbon Dioxide Capture and Concentration

    Energy Technology Data Exchange (ETDEWEB)

    James Ritter; Armin Ebner; Steven Reynolds Hai Du; Amal Mehrotra

    2008-07-31

    The objective of this three-year project was to study new pressure swing adsorption (PSA) cycles for CO{sub 2} capture and concentration at high temperature. The heavy reflux (HR) PSA concept and the use of a hydrotalcite like (HTlc) adsorbent that captures CO{sub 2} reversibly at high temperatures simply by changing the pressure were two key features of these new PSA cycles. Through the completion or initiation of nine tasks, a bench-scale experimental and theoretical program has been carried out to complement and extend the process simulation study that was carried out during Phase I (DE-FG26-03NT41799). This final report covers the entire project from August 1, 2005 to July 31, 2008. This program included the study of PSA cycles for CO{sub 2} capture by both rigorous numerical simulation and equilibrium theory analysis. The insight gained from these studies was invaluable toward the applicability of PSA for CO{sub 2} capture, whether done at ambient or high temperature. The rigorous numerical simulation studies showed that it is indeed possible to capture and concentrate CO{sub 2} by PSA. Over a wide range of conditions it was possible to achieve greater than 90% CO{sub 2} purity and/or greater than 90% CO{sub 2} recovery, depending on the particular heavy reflux (HR) PSA cycle under consideration. Three HR PSA cycles were identified as viable candidates for further study experimentally. The equilibrium theory analysis, which represents the upper thermodynamic limit of the performance of PSA process, further validated the use of certain HR PSA cycles for CO{sub 2} capture and concentration. A new graphical approach for complex PSA cycle scheduling was also developed during the course of this program. This new methodology involves a priori specifying the cycle steps, their sequence, and the number of beds, and then following a systematic procedure that requires filling in a 2-D grid based on a few simple rules, some heuristics and some experience. It has been

  19. LIFE CYCLE OF INFORMATION SYSTEMS

    Directory of Open Access Journals (Sweden)

    Y. S. Sennik

    2015-01-01

    Full Text Available This work is a generalization of the theoretical propositions related to the life cycle of information systems. There was given the definition of the life cycle, specify which items you should include every step of the cycle. Describes the methodology division of the life cycle on the main stage, including methodology Rational Unified Process. The description of the fundamental standards in this area. Special attention was paid to the work of the basic life cycle models. It was carried out their comparative characteristics. On the basis of the theoretical propositions, it was concluded that the preferred model of the life cycle for the corporate network is a spiral model and the use of international standards in the life cycle saves a lot of effort, time and material resources.

  20. Two Quantum Polytropic Cycles

    Science.gov (United States)

    Arias-Hernández, L. A.; Morales-Serrano, A. F.

    2002-11-01

    In this work we follow the Bender et al paper [1] to study the quantum analogues of the Stirling and Ericsson polytropic cycles. In the context of the classical thermodynamics, the Stirling and Ericsson cycles correspond to reversible heat engines with two isothermal processes joined by two polytropic branches which occur in a device called regenerator. If this device is an ideal one, the efficiency of these cycles is the Carnot efficiency. Here, we introduce the quantum analogues of the Stirling and Ericsson cycles, the first one based on a double square potential well with a finite potential barrier, since in this system the tunnel effect could be the analogue to the regeneration classical process, therefore the isochoric quantum branches would really correspond to an internal energy storage, and the last one with an unknown system where the isobaric quantum processes don't induce changes in its quantum state. With these systems the quantum engines have cycles consisting of polytropic and isothermal quantum processes analogues to the corresponding classical processes. We show that in both cases the quantum cycles have an efficiency given by ηCQM = 1 - EC/EH, which is the same expression for the quantum analogue of the Carnot cycle studied by Bender.

  1. Cycling and Female Sexual and Urinary Function: Results From a Large, Multinational, Cross-Sectional Study.

    Science.gov (United States)

    Gaither, Thomas W; Awad, Mohannad A; Murphy, Gregory P; Metzler, Ian; Sanford, Thomas; Eisenberg, Michael L; Sutcliffe, Siobhan; Osterberg, E Charles; Breyer, Benjamin N

    2018-04-01

    Bicycle riding has become an increasingly popular mode of transportation and exercise, especially among women, and previous studies have demonstrated a relationship between cycling and sexual dysfunction, albeit using non-validated questionnaires. We aimed to explore the relationship between cycling and sexual and urinary dysfunction. Cyclists were recruited to complete a survey through Facebook advertisements and outreach to sporting clubs across 5 English-speaking countries. Swimmers and runners were recruited as a comparison group. Participants were queried using validated questionnaires, including the Female Sexual Function Index, the American Urological Association Symptom Index, and non-validated questions about history of urinary tract infections (UTIs), genital numbness, and genital saddle sores (all self-reported). 3,118 (53.3%) Women completed the survey, comprising 1,053 (34%) non-cyclists, 1,656 (53%) low-intensity cyclists, and 409 (13%) high-intensity cyclists. After adjusting for age, body mass index, hypertension, diabetes, ischemic heart disease, tobacco use, race, marital status, urinary symptoms, and sexual activity, high-intensity cyclists had lower odds of self-reported sexual dysfunction compared to non-cyclists (adjusted odds ratio [aOR] 0.7, P = .02). There were no statistically significant differences in urinary symptoms across groups. Compared to non-cyclists, both low- and high-intensity cyclists had higher odds of reporting a previous UTI (aOR 1.4, P < .001, and aOR 1.4, P = .009, respectively), genital numbness (odds ratio [OR] 6.5, P < .001, and OR 9.1, P < .001, respectively), and saddle sores (OR 6.3, P < .001, and OR 22.7, P < .001, respectively). Women cyclists were more likely to report other genitourinary conditions, including UTIs, genital numbness, and saddle sores. This is the largest study comparing cyclists to other athletes with respect to sexual and urinary function. The study is limited by its cross-sectional design

  2. Contemporary and prospective fuel cycles for WWER-440 based on new assemblies with higher uranium capacity and higher average fuel enrichment

    International Nuclear Information System (INIS)

    Gagarinskiy, A.A.; Saprykin, V.V.

    2009-01-01

    RRC 'Kurchatov Institute' has performed an extensive cycle of calculations intended to validate the opportunities of improving different fuel cycles for WWER-440 reactors. Works were performed to upgrade and improve WWER-440 fuel cycles on the basis of second-generation fuel assemblies allowing core thermal power to be uprated to 107 108 % of its nominal value (1375 MW), while maintaining the same fuel operation lifetime. Currently intensive work is underway to develop fuel cycles based on second-generation assemblies with higher fuel capacity and average fuel enrichment per assembly increased up to 4.87 % of U-235. Fuel capacity of second-generation assemblies was increased by means of eliminated central apertures of fuel pellets, and pellet diameter extended due to reduced fuel cladding thickness. This paper intends to summarize the results of works performed in the field of WWER-440 fuel cycle modernization, and to present yet unemployed opportunities and prospects of further improvement of WWER-440 neutronic and operating parameters by means of additional optimization of fuel assembly designs and fuel element arrangements applied. (Authors)

  3. Development of 80- and 100- Mile Work Day Cycles Representative of Commercial Pickup and Delivery Operation

    Energy Technology Data Exchange (ETDEWEB)

    Duran, Adam W [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Kelly, Kenneth J [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Kresse, John [Cummins; Li, Ke [Cummins

    2018-04-03

    When developing and designing new technology for integrated vehicle systems deployment, standard cycles have long existed for chassis dynamometer testing and tuning of the powertrain. However, to this day with recent developments and advancements in plug-in hybrid and battery electric vehicle technology, no true 'work day' cycles exist with which to tune and measure energy storage control and thermal management systems. To address these issues and in support of development of a range-extended pickup and delivery Class 6 commercial vehicle, researchers at the National Renewable Energy Laboratory in collaboration with Cummins analyzed 78,000 days of operational data captured from more than 260 vehicles operating across the United States to characterize the typical daily performance requirements associated with Class 6 commercial pickup and delivery operation. In total, over 2.5 million miles of real-world vehicle operation were condensed into a pair of duty cycles, an 80-mile cycle and a 100-mile cycle representative of the daily operation of U.S. class 3-6 commercial pickup and delivery trucks. Using novel machine learning clustering methods combined with mileage-based weighting, these composite representative cycles correspond to 90th and 95th percentiles for daily vehicle miles traveled by the vehicles observed. In addition to including vehicle speed vs time drive cycles, in an effort to better represent the environmental factors encountered by pickup and delivery vehicles operating across the United States, a nationally representative grade profile and key status information were also appended to the speed vs. time profiles to produce a 'work day' cycle that captures the effects of vehicle dynamics, geography, and driver behavior which can be used for future design, development, and validation of technology.

  4. Modelling the pelagic nitrogen cycle and vertical particle flux in the Norwegian sea

    Science.gov (United States)

    Haupt, Olaf J.; Wolf, Uli; v. Bodungen, Bodo

    1999-02-01

    A 1D Eulerian ecosystem model (BIological Ocean Model) for the Norwegian Sea was developed to investigate the dynamics of pelagic ecosystems. The BIOM combines six biochemical compartments and simulates the annual nitrogen cycle with specific focus on production, modification and sedimentation of particles in the water column. The external forcing and physical framework is based on a simulated annual cycle of global radiation and an annual mixed-layer cycle derived from field data. The vertical resolution of the model is given by an exponential grid with 200 depth layers, allowing specific parameterization of various sinking velocities, breakdown of particles and the remineralization processes. The aim of the numerical experiments is the simulation of ecosystem dynamics considering the specific biogeochemical properties of the Norwegian Sea, for example the life cycle of the dominant copepod Calanus finmarchicus. The results of the simulations were validated with field data. Model results are in good agreement with field data for the lower trophic levels of the food web. With increasing complexity of the organisms the differences increase between simulated processes and field data. Results of the numerical simulations suggest that BIOM is well adapted to investigate a physically controlled ecosystem. The simulation of grazing controlled pelagic ecosystems, like the Norwegian Sea, requires adaptations of parameterization to the specific ecosystem features. By using seasonally adaptation of the most sensible processes like utilization of light by phytoplankton and grazing by zooplankton results were greatly improved.

  5. Explicating Validity

    Science.gov (United States)

    Kane, Michael T.

    2016-01-01

    How we choose to use a term depends on what we want to do with it. If "validity" is to be used to support a score interpretation, validation would require an analysis of the plausibility of that interpretation. If validity is to be used to support score uses, validation would require an analysis of the appropriateness of the proposed…

  6. Increasing thermal efficiency of Rankine cycles by using refrigeration cycles: A theoretical analysis

    International Nuclear Information System (INIS)

    Sarr, Joachim-André Raymond; Mathieu-Potvin, François

    2016-01-01

    Highlights: • A new stratagem is proposed to improve thermal efficiency of Rankine cycles. • Three new configurations are optimized by means of numerical simulations. • The Rankine-1SCR design is advantageous for 1338 different fluid combinations. • The Rankine-2SCR design is advantageous for 772 different fluid combinations. • The Rankine-3SCR design is advantageous for 768 different fluid combinations. - Abstract: In this paper, three different modifications of the basic Rankine thermodynamic cycle are proposed. The objective is to increase the thermal efficiency of power systems based on Rankine cycles. The three new systems are named “Rankine-1SCR”, “Rankine-2SCR”, and “Rankine-3SCR” cycles, and they consist of linking a refrigeration cycle to the basic Rankine cycle. The idea is to use the refrigeration cycle to create a low temperature heat sink for the Rankine cycle. These three new power plant configurations are modeled and optimized with numerical tools, and then they are compared with the basic Rankine cycle. The objective function is the thermal efficiency of the systems (i.e., net power output (kW) divided by heat rate (kW) entering the system), and the design variables are the operating temperatures within the systems. Among the 84 × 84 (i.e., 7056) possible combinations of working and cooling fluids investigated in this paper, it is shown that: (i) the Rankine-1SCR system is advantageous for 1338 different fluid combinations, (ii) the Rankine-2SCR system is advantageous for 772 different fluid combinations, and (iii) the Rankine-3SCR system is advantageous for 768 different fluid combinations.

  7. Hybrid Combined Cycles with Biomass and Waste Fired Bottoming Cycle - a Literature Study

    Energy Technology Data Exchange (ETDEWEB)

    Petrov, Miroslav P.

    2002-02-01

    Biomass is one of the main natural resources in Sweden. The present low-CO{sub 2} emission characteristics of the Swedish electricity production system (hydro and nuclear) can be retained only by expansion of biofuel applications for energy purposes. Domestic Swedish biomass resources are vast and renewable, but not infinite. They must be utilized as efficiently as possible, in order to make sure that they meet the conditions for sustainability in the future. Application of efficient power generation cycles at low costs is essential for meeting this challenge. This applies also to municipal solid waste incineration with energy extraction, which should be preferred to its dumping in landfills. Hybrid dual-fuel combined cycle units are a simple and affordable way to increase the electric efficiency of biofuel energy utilization, without big investments, uncertainties or loss of reliability arising from complicated technologies. Configurations of such power cycles are very flexible and reliable. Their potential for high electric efficiency in condensing mode, high total efficiency in combined heat and power mode and unrivalled load flexibility is explored in this project. The present report is a literature study that concentrates on certain biomass utilization technologies, in particular the design and performance of hybrid combined cycle power units of various configurations, with gas turbines and internal combustion engines as topping cycles. An overview of published literature and general development trends on the relevant topic is presented. The study is extended to encompass a short overview of biomass utilization as an energy source (focusing on Sweden), history of combined cycles development with reference especially to combined cycles with supplementary firing and coal-fired hybrid combined cycles, repowering of old steam units into hybrid ones and combined cycles for internal combustion engines. The hybrid combined cycle concept for municipal solid waste

  8. Impact of resolving the diurnal cycle in an ocean-atmosphere GCM. Pt. 1: a diurnally forced OGCM

    Energy Technology Data Exchange (ETDEWEB)

    Bernie, D.J. [University of Reading, National Centre for Atmospheric Science - Climate, Department of Meteorology, Reading (United Kingdom); Laboratoire d' Oceanographie et du Climat, Experimentation et Approches Numeriques, IPSL, Paris (France); Met Office Hadley Centre, Exeter, EX1 3PB (United Kingdom); Guilyardi, E. [University of Reading, National Centre for Atmospheric Science - Climate, Department of Meteorology, Reading (United Kingdom); Laboratoire d' Oceanographie et du Climat, Experimentation et Approches Numeriques, IPSL, Paris (France); Madec, G. [Laboratoire d' Oceanographie et du Climat, Experimentation et Approches Numeriques, IPSL, Paris (France); Slingo, J.M.; Woolnough, S.J. [University of Reading, National Centre for Atmospheric Science - Climate, Department of Meteorology, Reading (United Kingdom)

    2007-11-15

    The diurnal cycle is a fundamental time scale in the climate system, at which the upper ocean and atmosphere are routinely observed to vary. Current climate models, however, are not configured to resolve the diurnal cycle in the upper ocean or the interaction of the ocean and atmosphere on these time scales. This study examines the diurnal cycle of the tropical upper ocean and its climate impacts. In the present paper, the first of two, a high vertical resolution ocean general circulation model (OGCM), with modified physics, is developed which is able to resolve the diurnal cycle of sea surface temperature (SST) and current variability in the upper ocean. It is then validated against a satellite derived parameterization of diurnal SST variability and in-situ current observations. The model is then used to assess rectification of the intraseasonal SST response to the Madden-Julian oscillation (MJO) by the diurnal cycle of SST. Across the equatorial Indo-Pacific it is found that the diurnal cycle increases the intraseasonal SST response to the MJO by around 20%. In the Pacific, the diurnal cycle also modifies the exchange of momentum between equatorially divergent Ekman currents and the meridionally convergent geostrophic currents beneath, resulting in a 10% increase in the strength of the Ekman cells and equatorial upwelling. How the thermodynamic and dynamical impacts of the diurnal cycle effect the mean state, and variability, of the climate system cannot be fully investigated in the constrained design of ocean-only experiments presented here. The second part of this study, published separately, addresses the climate impacts of the diurnal cycle in the coupled system by coupling the OGCM developed here to an atmosphere general circulation model. (orig.)

  9. Validated assessment scales for the lower face.

    Science.gov (United States)

    Narins, Rhoda S; Carruthers, Jean; Flynn, Timothy C; Geister, Thorin L; Görtelmeyer, Roman; Hardas, Bhushan; Himmrich, Silvia; Jones, Derek; Kerscher, Martina; de Maio, Maurício; Mohrmann, Cornelia; Pooth, Rainer; Rzany, Berthold; Sattler, Gerhard; Buchner, Larry; Benter, Ursula; Breitscheidel, Lusine; Carruthers, Alastair

    2012-02-01

    Aging in the lower face leads to lines, wrinkles, depression of the corners of the mouth, and changes in lip volume and lip shape, with increased sagging of the skin of the jawline. Refined, easy-to-use, validated, objective standards assessing the severity of these changes are required in clinical research and practice. To establish the reliability of eight lower face scales assessing nasolabial folds, marionette lines, upper and lower lip fullness, lip wrinkles (at rest and dynamic), the oral commissure and jawline, aesthetic areas, and the lower face unit. Four 5-point rating scales were developed to objectively assess upper and lower lip wrinkles, oral commissures, and the jawline. Twelve experts rated identical lower face photographs of 50 subjects in two separate rating cycles using eight 5-point scales. Inter- and intrarater reliability of responses was assessed. Interrater reliability was substantial or almost perfect for all lower face scales, aesthetic areas, and the lower face unit. Intrarater reliability was high for all scales, areas and the lower face unit. Our rating scales are reliable tools for valid and reproducible assessment of the aging process in lower face areas. © 2012 by the American Society for Dermatologic Surgery, Inc. Published by Wiley Periodicals, Inc.

  10. High-intensity cycle interval training improves cycling and running performance in triathletes.

    Science.gov (United States)

    Etxebarria, Naroa; Anson, Judith M; Pyne, David B; Ferguson, Richard A

    2014-01-01

    Effective cycle training for triathlon is a challenge for coaches. We compared the effects of two variants of cycle high-intensity interval training (HIT) on triathlon-specific cycling and running. Fourteen moderately-trained male triathletes ([Formula: see text]O2peak 58.7 ± 8.1 mL kg(-1) min(-1); mean ± SD) completed on separate occasions a maximal incremental test ([Formula: see text]O2peak and maximal aerobic power), 16 × 20 s cycle sprints and a 1-h triathlon-specific cycle followed immediately by a 5 km run time trial. Participants were then pair-matched and assigned randomly to either a long high-intensity interval training (LONG) (6-8 × 5 min efforts) or short high-intensity interval training (SHORT) (9-11 × 10, 20 and 40 s efforts) HIT cycle training intervention. Six training sessions were completed over 3 weeks before participants repeated the baseline testing. Both groups had an ∼7% increase in [Formula: see text]O2peak (SHORT 7.3%, ±4.6%; mean, ±90% confidence limits; LONG 7.5%, ±1.7%). There was a moderate improvement in mean power for both the SHORT (10.3%, ±4.4%) and LONG (10.7%, ±6.8%) groups during the last eight 20-s sprints. There was a small to moderate decrease in heart rate, blood lactate and perceived exertion in both groups during the 1-h triathlon-specific cycling but only the LONG group had a substantial decrease in the subsequent 5-km run time (64, ±59 s). Moderately-trained triathletes should use both short and long high-intensity intervals to improve cycling physiology and performance. Longer 5-min intervals on the bike are more likely to benefit 5 km running performance.

  11. Combined Turbine and Cycle Optimization for Organic Rankine Cycle Power Systems—Part A

    DEFF Research Database (Denmark)

    Meroni, Andrea; La Seta, Angelo; Andreasen, Jesper Graa

    2016-01-01

    Axial-flow turbines represent a well-established technology for a wide variety of power generation systems. Compactness, flexibility, reliability and high efficiency have been key factors for the extensive use of axial turbines in conventional power plants and, in the last decades, in organic...... Rankine cycle power systems. In this two-part paper, an overall cycle model and a model of an axial turbine were combined in order to provide a comprehensive preliminary design of the organic Rankine cycle unit, taking into account both cycle and turbine optimal designs. Part A presents the preliminary...

  12. Menstrual cycle pattern and fertility

    DEFF Research Database (Denmark)

    Kolstad, Henrik A.; Bonde, Jens Peter; Hjøllund, Niels Henrik

    1999-01-01

    To characterize how the menstrual cycle pattern relates to fertility regardless of potential biases caused by inappropriate coital timing during the menstrual cycle or early embryonal loss.......To characterize how the menstrual cycle pattern relates to fertility regardless of potential biases caused by inappropriate coital timing during the menstrual cycle or early embryonal loss....

  13. Born at the right time? Childhood health and the business cycle.

    Science.gov (United States)

    Angelini, Viola; Mierau, Jochen O

    2014-05-01

    We analyze the relationship between the state of the business cycle at birth and childhood health. We use a retrospective survey on self-reported childhood health for ten Western European countries and combine it with historically and internationally comparable data on the Gross Domestic Product. We validate the self-reported data by comparing them to realized illness spells. We find a positive relationship between being born in a recession and childhood health. This relationship is not driven by selection effects due to heightened infant mortality during recessions. Placebo regressions indicate that the observed effect is not spurious. Copyright © 2014 Elsevier Ltd. All rights reserved.

  14. Numerical analysis of the heat and mass transfer processes in selected M-Cycle heat exchangers for the dew point evaporative cooling

    International Nuclear Information System (INIS)

    Pandelidis, Demis; Anisimov, Sergey

    2015-01-01

    Highlights: • The comparative numerical study of the eight M-Cycle heat exchangers was presented. • The mathematical model is compared against the experimental data. • The results show, that the original M-Cycle heat and mass exchanger can be improved. • The effectiveness of the heat and mass exchangers depends strongly on the inlet air parameters. - Abstract: This paper investigates a mathematical simulation of heat and mass transfer in eight different types of the Maisotsenko Cycle (M-Cycle) heat and mass exchangers (HMXs) used for indirect evaporative air cooling. A two-dimensional heat and mass transfer model is developed to perform the thermal calculations of the indirect evaporative cooling process and quantifying the overall performance. The mathematical model was validated against experimental data. A numerical simulation reveals many unique features of the considered HMXs, enabling an accurate prediction of their performance. Results of the model allow for comparison of the analyzed devices in order to improve the performance of the original HMX

  15. Spatio-temporal structure and cycle to cycle variations of an in-cylinder tumbling flow

    Science.gov (United States)

    Voisine, M.; Thomas, L.; Borée, J.; Rey, P.

    2011-05-01

    The aim of this paper is to make use of PIV and high-speed PIV in a research engine of moderate tumbling ratio in order to analyze both the spatial structure of the flow and its temporal evolution during series of consecutive cycles. Appropriate analyzing tools are introduced, and four different points are addressed: (1) the chain of events driving the generation of the three-dimensional mean tumbling motion is investigated; (2) a Lagrangian analysis of the roll-up of the tumbling jet in individual cycles demonstrates a strong cycle to cycle variation during the compression phase (the rms of the position of the jet front being approximately 10% of the piston stroke); (3) focussing on the "breakdown" phase, phase invariant proper orthogonal decomposition enables us to distinguish cycles according to their structure near top dead center (TDC). We show that when the coherent energy of the flow is conserved, there is no increase in the fluctuating kinetic energy; (4) finally, the phase-averaged Reynolds stresses is decomposed into a contribution of the in-cycle coherence and the turbulence carried by the flow states. Approximately 30% of the fluctuating kinetic energy is due to cycle to cycle fluctuations in this chamber near TDC.

  16. Nutrient cycling strategies.

    NARCIS (Netherlands)

    Breemen, van N.

    1995-01-01

    This paper briefly reviews pathways by which plants can influence the nutrient cycle, and thereby the nutrient supply of themselves and of their competitors. Higher or lower internal nutrient use efficiency positively feeds back into the nutrient cycle, and helps to increase or decrease soil

  17. Universal cycle periods

    NARCIS (Netherlands)

    Groot, de E.A. (Bert); Franses, P.H.P.H.

    2009-01-01

    We present a meta-analysis of cycles in historical economic data. The literature on stochastic and deterministic cycles in variables such as the consumer price index, employment, interest rates, commodity prices, and GDP is huge and scattered, but our meta-analysis reveals various communalities. Our

  18. Predicting the start and maximum amplitude of solar cycle 24 using similar phases and a cycle grouping

    International Nuclear Information System (INIS)

    Wang Jialong; Zong Weiguo; Le Guiming; Zhao Haijuan; Tang Yunqiu; Zhang Yang

    2009-01-01

    We find that the solar cycles 9, 11, and 20 are similar to cycle 23 in their respective descending phases. Using this similarity and the observed data of smoothed monthly mean sunspot numbers (SMSNs) available for the descending phase of cycle 23, we make a date calibration for the average time sequence made of the three descending phases of the three cycles, and predict the start of March or April 2008 for cycle 24. For the three cycles, we also find a linear correlation of the length of the descending phase of a cycle with the difference between the maximum epoch of this cycle and that of its next cycle. Using this relationship along with the known relationship between the rise-time and the maximum amplitude of a slowly rising solar cycle, we predict the maximum SMSN of cycle 24 of 100.2 ± 7.5 to appear during the period from May to October 2012. (letters)

  19. Contribution to the validation of thermal ratchetting prevision methods in metallic structures; Contribution a la validation des methodes de prevision du rochet thermique dans les structures metalliques

    Energy Technology Data Exchange (ETDEWEB)

    Rakotovelo, A.M

    1998-03-01

    This work concerns the steady state assessment in the metallic structures subjected to thermomechanical cyclic loadings in biaxial stress state. The effect of the short time mechanical overloads is also investigated. The first chapter is devoted to a bibliographic research concerning the behaviour of the materials and the structures in the cyclic plasticity. Some works relate to the experimental aspect as well as the numerical one for the steady state assessment of such structures are presented. The experimental part of the study is presented in the second chapter. The experimental device was carried out in order to prescribe tension and torsion forces combined with cyclic thermal loading. Some tests was then carried out, among these tests certain include some overloads in tension or torsion. The last chapter describes the numerical calculations using different models (linear isotropic hardening, linear kinematic hardening and elasto-viscoplastic Chaboche's model) and the application of some simplified methods for the ratchetting assessment in the structures. We have considered two categories of methods. The first one is based on an elastic analysis (Bree's diagram, 3 Sm rule, efficiency rule) and the second one combines elastic analysis and elastoplastic analysis of the first cycle (Gatt's and Taleb's methods). The results of this study have enabled: to validate in the biaxial stress state an expression which takes into account the effect of mechanical short time overloads; to test the performances of considered models to describe the evolution of the structure during the first cycle and to take into account the effect of short time overloads. Among the considered models, the elastoplastic Chaboche's model seems to be the most accurate to describe the structure's behaviour during the first cycles; to validate some simplified methods. Certain methods based only on elastic analysis (Bee's diagram and efficiency rule) seem not

  20. Hydrogen production by the iodine-sulphur thermochemical cycle. Total and partial pressure measurements

    International Nuclear Information System (INIS)

    D Doizi; V Dauvois; J L Roujou; V Delanne; P Fauvet; B Larousse; O Hercher; P Carles; C Moulin

    2006-01-01

    The iodine sulphur thermochemical cycle appears to be one of the most promising candidate for the massive production of hydrogen using nuclear energy. The key step in this cycle is the HI distillation section which must be optimized to get a good efficiency of the overall cycle. The concept of reactive versus extractive distillation of HI has been proposed because of its potentiality. The design and the optimization of the reactive distillation column requires the knowledge of the liquid vapour equilibrium over the ternary HI-I 2 -H 2 O mixtures up to 300 C and 100 bars. A general methodology based on three experimental devices imposed by the very corrosive and concentrated media will be described: 1) I1 for the total pressure measurement versus different ternary compositions. 2) I2 for the partial and total pressure measurements around 130 C and 2 bars to validate the choice of the analytical optical 'online' techniques we have proposed. 3) I3 for the partial and total pressures measurements in the process domain. The results obtained on pure samples, binary mixtures HI-H 2 O and ternary mixtures using an experimental design analysis in the experimental device I2 will be discussed. (authors)