WorldWideScience

Sample records for cycle systems phase

  1. Novel BCH Code Design for Mitigation of Phase Noise Induced Cycle Slips in DQPSK Systems

    DEFF Research Database (Denmark)

    Leong, M. Y.; Larsen, Knud J.; Jacobsen, G.

    2014-01-01

    We show that by proper code design, phase noise induced cycle slips causing an error floor can be mitigated for 28 Gbau d DQPSK systems. Performance of BCH codes are investigated in terms of required overhead......We show that by proper code design, phase noise induced cycle slips causing an error floor can be mitigated for 28 Gbau d DQPSK systems. Performance of BCH codes are investigated in terms of required overhead...

  2. Phase-amplitude reduction of transient dynamics far from attractors for limit-cycling systems

    Science.gov (United States)

    Shirasaka, Sho; Kurebayashi, Wataru; Nakao, Hiroya

    2017-02-01

    Phase reduction framework for limit-cycling systems based on isochrons has been used as a powerful tool for analyzing the rhythmic phenomena. Recently, the notion of isostables, which complements the isochrons by characterizing amplitudes of the system state, i.e., deviations from the limit-cycle attractor, has been introduced to describe the transient dynamics around the limit cycle [Wilson and Moehlis, Phys. Rev. E 94, 052213 (2016)]. In this study, we introduce a framework for a reduced phase-amplitude description of transient dynamics of stable limit-cycling systems. In contrast to the preceding study, the isostables are treated in a fully consistent way with the Koopman operator analysis, which enables us to avoid discontinuities of the isostables and to apply the framework to system states far from the limit cycle. We also propose a new, convenient bi-orthogonalization method to obtain the response functions of the amplitudes, which can be interpreted as an extension of the adjoint covariant Lyapunov vector to transient dynamics in limit-cycling systems. We illustrate the utility of the proposed reduction framework by estimating the optimal injection timing of external input that efficiently suppresses deviations of the system state from the limit cycle in a model of a biochemical oscillator.

  3. Results of FY 2002 of feasibility study on commercialized fast reactor cycle systems. Phase 2

    International Nuclear Information System (INIS)

    2003-06-01

    Japan Nuclear Cycle Development Institute (JNC) and Japan Atomic Power Company (JAPC, that is the representative of the electric utilities in Japan) established a new organization to develop a commercialized fast reactor (FR) cycle system on July 1, 1999 and feasibility study (F/S) was undertaken in order to determine the promising concepts and to define the necessary R and D tasks. During Phase 1 (JFY 1999 and 2000), a number of candidate concepts were screened from various options, featuring innovative technologies. In the F/S, the options were evaluated and conceptual designs were examined considering the attainable perspectives for following: 1) ensuring safety, 2) economic competitiveness to future LWRs, 3) efficient utilization of resources, 4) reduction of environmental burden and 5) enhancement of nuclear non-proliferation. The F/S should also guide the necessary R and D to commercialize FR cycle system. To begin with the study of feasible candidate concepts screened in Phase I, Phase 2 started in the plan for five years in 2001. This aims at clarifying several feasible candidate concepts and deciding the research plan after Phase 3 as taking into consideration the innovative technology. As for this plan, an interim report will be carried out in 2003 as one pause and the prospect to clarify the feasible candidates will be expected. Furthermore, after the completion of this research and investigation program, research and development activities will be carried out under a rolling plan in which reviews will be carried out approximately every five years. The objective of these R and D activities is to make a proposal regarding highly attractive and competitive FR cycle system technology that assures safety by 2015. This report summarizes the results of F/S of Phase 2 in 2002. In 2002, the second year of Phase 2, the study was advanced along with the plan which was evaluated by the committee for the Evaluation. Then, in the study of FR system and fuel cycle

  4. Feasibility study on commercialized fast reactor cycle systems. Phase II final report

    International Nuclear Information System (INIS)

    Ieda, Yoshiaki; Uchikawa, Sadao; Okubo, Tsutomu; Ono, Kiyoshi; Kato, Atsushi; Kurisaka, Kenichi; Sakamoto, Yoshihiko; Sato, Kazujiro; Sato, Koji; Chikazawa, Yoshitaka; Nakai, Ryodai; Nakabayashi, Hiroki; Nakamura, Hirofumi; Namekawa, Takashi; Niwa, Hajime; Nomura, Kazunori; Hayashi, Hideyuki; Hayafune, Hiroki; Hirao, Kazunori; Mizuno, Tomoyasu; Muramatsu, Toshiharu; Ando, Masato; Ono, Katsumi; Ogata, Takanari; Kubo, Shigenobu; Kotake, Shoji; Sagayama, Yutaka; Takakuma, Katsuyuki; Tanaka, Toshihiko; Namba, Takashi; Fujii, Sumio; Muramatsu, Kazuyoshi

    2006-06-01

    A joint project team of Japan Atomic Energy Agency and the Japan Atomic Power Company (as the representative of the electric utilities) started the feasibility study on commercialized fast reactor cycle systems (F/S) in July 1999 in cooperation with Central Research Institute of Electric Power Industry and vendors. On the major premise of safety assurance, F/S aims to present an appropriate picture of commercialization of fast reactor (FR) cycle system which has economic competitiveness with light water reactor cycle systems and other electricity base load systems, and to establish FR cycle technologies for the future major energy supply. In the period from Japanese fiscal year (JFY) 1999 to 2000, the phase-I of F/S was carried out to screen our representative FR, reprocessing and fuel fabrication technologies. In the phase-II (JFY 2001-2005), the design study of FR cycle concepts, the development of significant technologies necessary for the feasibility evaluation, and the confirmation of key technical issues were performed to clarify the promising candidate concepts toward the commercialization. In this final phase-II report clarified the most promising concept, the R and D plan until around 2015, and the key issues for the commercialization. Based on the comprehensive evaluation in F/S, the combination of the sodium-cooled FR with MOX fuel core, the advanced-aqueous reprocessing process and the simplified-pelletizing fuel fabrication process was recommended as the mainline choice for the most promising concept. The concept exceeds in technical advancement, and the conformity to the development targets was higher compared with that of the others. Alternative technologies are prepared to be decrease the development risk of innovative technologies in the mainline choice. (author)

  5. Feasibility study on commercialization of fast breeder reactor cycle system. Interim report of phase 2. Technical study report on synthetic evaluation for FBR cycle

    International Nuclear Information System (INIS)

    Shiotani, Hiroki; Ohtaki, Akira; Ono, Kiyoshi; Yasumatsu, Naoto; Kubota, Sadae; Heta, Masanori

    2004-09-01

    This report presents the outline of the development and the results of Synthetic evaluation on the candidate Fast Reactor (FR) cycle system concepts, scenario study on FR cycle deployment and cost-benefit analysis on the candidate FR cycle system concepts in the interim evaluation (FY2001 through FY2003) of the phase 2 of the Japanese 'Feasibility Study on Commercialization of Fast Reactor Cycle System (FS)'. The characteristic evaluation extended to evaluate a new view point of social acceptance besides the viewpoints of safety, economics, reduction of environmental burden, efficient utilization of uranium resource, proliferation resistance, and technical feasibility, which has been considered since the phase 1 of FS. As for the six view points, hierarchy structures and utility functions for quantitative evaluation have been developed and/or improved. Furthermore, the methodology for weighing the viewpoints, which was also developed, made it possible to examine the characteristics of the candidate concepts from all the seven viewpoints. Generally, the FR cycles with sodium-cooled FR were highly evaluated. The characteristic evaluation for alternative power supply systems was also tried in this report for the first time. FR cycle deployment scenarios clarified the necessity of FR cycle deployment and the desirable core features, etc. through the long-term mass flow analysis, which includes comparison among other nuclear fuel cycle schemes and analysis for evaluating the degree to meet future needs, on the typical FR cycle systems. Regarding cost-benefit analysis, both the amount of the cost estimated by the past R and D and the cost in the Road map of FS are used as the investment for FR cycle research and development (R and D), the results showed that the benefit derived from the commercialization of FR cycle will be more than the investment. (author)

  6. Experimental study on the application of phase change material in the dynamic cycling of battery pack system

    International Nuclear Information System (INIS)

    Yan, Jiajia; Li, Ke; Chen, Haodong; Wang, Qingsong; Sun, Jinhua

    2016-01-01

    Highlights: • Two temperature peaks are observed in the single battery during the dynamic cycling. • The cooling performance of PCM system is superior to the natural convection system. • Increasing the laying-aside time is beneficial to the cooling performance of PCM system. • The optimal phase change temperature of PCM is recommended as 45 °C. - Abstract: The thermal performance of phase change material (PCM) based battery thermal management system in dynamic cycling is investigated, and several factors influencing the PCM system are discussed in detail. It is established that the surface temperature of a single battery has two temperature peaks during one charge/discharge cycle, while it disappears in the PCM system for the temperature buffering of PCM. In addition, the cooling performance of the PCM system is superior to that of natural convection system especially at a high current rate. Moreover, increasing the laying-aside time properly between each cycling step is beneficial to the cooling performance of the PCM system. Additionally, PCM with a phase change temperature of 45 °C is recommended to be used in the real battery pack system.

  7. Experimental Studies of Phase Change and Microencapsulated Phase Change Materials in a Cold Storage/Transportation System with Solar Driven Cooling Cycle

    OpenAIRE

    Lin Zheng; Wei Zhang; Fei Liang; Shuang Lin; Xiangyu Jin

    2017-01-01

    The paper presents the different properties of phase change material (PCM) and Microencapsulated phase change material (MEPCM) employed to cold storage/transportation system with a solar-driven cooling cycle. Differential Scanning Calorimeter (DSC) tests have been performed to analyze the materials enthalpy, melting temperature range, and temperature range of solidification. KD2 Pro is used to test the thermal conductivities of phase change materials slurry and the results were used to compar...

  8. Feasibility study on commercialization of fast breeder reactor cycle systems interim report of phase II. Technical study report for nuclear fuel cycle systems

    International Nuclear Information System (INIS)

    Sato, Koji; Amamoto, Ippei; Inoue, Akira

    2004-06-01

    As a part of the feasibility study on commercialization of fast breeder reactor cycle systems, the plant concept concerning the fuel cycle systems (combination of the reprocessing and the fuel fabrication) has been constructed to reduce their total cost by the introduction of various innovative techniques and to apply their utmost superior efficiency from such standpoints of a decrease in the environmental burden, better resource utilization and proliferation resistance improvement by the low decontamination transuranium element (TRU) recycle. This interim report of Phase II describes the results of an on-going study which will cover a five-year period. For oxide fuels, the system which combines the use of the advanced aqueous reprocessing using three main methods such as the crystallization method, the simplified solvent extraction method, and the extraction chromatography method for minor actinide (MA) recovery, as well as the simplified pelletizing fuel fabrication which rationalized a powder mixing process etc., has abundant current results and a high technical feasibility for the basic process. Though this system faces difficulties in the technical development of control technology of the extraction chromatography and the fabrication technology of low decontamination TRU fuel etc., its expected practical use is possible at an early stage. As for the super-critical direct extraction reprocessing, it is necessary to fulfill more basic data although further economical improvement of an advanced aqueous reprocessing is expected. The system which combines the advanced aqueous reprocessing and the gelation sphere packing fuel fabrication has the advantage of lesser dispersion of the fine powder due to the use of solution and granule in the fuel fabrication process. However, this system will shoulder additional cost for the reagent recovery process and the waste liquid treatment process due to need to dispose of a large bulk of process waste liquid. The system which

  9. Methodologies for verification and validation of expert systems as a function of component, criticality and life-cycle phase

    International Nuclear Information System (INIS)

    Miller, L.

    1992-01-01

    The review of verification and validation (V and V) methods presented here is based on results of the initial two tasks of a contract with the US Nuclear Regulatory Commission and the Electric Power Research Institute to Develop and Document Guidelines for Verifying and Validating Expert Systems. The first task was to review the applicability of conventional software techniques to expert systems; the second was to directly survey V and V practices associated with development of expert systems. Subsequent tasks will focus on selecting, synthesizing or developing V and V methods appropriate for the overall system, for specific expert systems components, and for different phases of the life-cycle. In addition, final guidelines will most likely be developed for each of three levels of expert systems: safety-related (systems whose functions directly relate to system safety, so-called safety-critical systems), important-to-safety (systems which support the critical safety functions), and non-safety (systems which are unrelated to safety functions). For the present purposes of categorizing and discussing various types of V and V methods, the authors simplify the life-cycle and consider only two aspects - systems validation phase. The authors identified a number of techniques for the first, combined, phase and two general classes of V and V techniques for the latter phase: static testing techniques, which do not involve execution of the system code, and dynamic testing techniques, which do. In the next two sections the author reviews first the applicability to expert systems of conventional V and V techniques and, second, the techniques expert system developers actually use. In the last section the authors make some general observations

  10. Technical study report on reprocessing systems. The report of the feasibility study on commercialized FR cycle systems (phase I)

    International Nuclear Information System (INIS)

    Tanaka, Hiroshi; Kawamura, Fumio; Kakehi, Isao

    2001-04-01

    As a part of the feasibility study (FS) on commercialized fast reactor (FR) cycle systems started on July 1999, the design studies and the technical assessments for various advanced reprocessing systems have been carried out. In this study, plant design for the advanced aqueous system and the three non-aqueous systems (oxide electrowinning method, metal electrorefining method, and fluoride volatility method) has been carried out, and each system has been evaluated mainly from the viewpoint of economics. The future R and D issues on the processes and systems have been also clarified. This report describes the results of the study for two years as final report of FS phase I. (1) The advanced aqueous system, based on the simplified PUREX process, has been shown to be much more economical than the conventional PUREX. The 200 tHM/y plant achieves the target of economics, but the 50 tHM/y plant can not achieve the target. (2) The promising alternative systems replaced for advanced aqueous are the supercritical fluid direct extraction method and amine extraction method from the economical viewpoint. The ion exchange method is promising as the process for minor actinide recovery. (3) For reprocessing MOX fuel, all non-aqueous plants with a capacity of 200 tHM/y achieve the economical target. For such a small capacity as 50 tHM/y, further rationalization of the process is required for the oxide electrowinning method and metal electrorefining method to attain the target, though they are more economical than the advanced aqueous system. (4) For metallic and nitride fuel reprocessing, a metal electrorefining system has been shown to be advantageous. (author)

  11. Technological study report on synthetic evaluation for FBR cycle. The report of the feasibility studies on commercialized FBR cycle system. Phase 1

    International Nuclear Information System (INIS)

    Shinoda, Yoshihiko; Ohtaki, Akira; Kofuji, Hirohide; Ono, Kiyoshi; Hirao, Kazunori

    2001-03-01

    This report is intended to explain the outline of the characteristic evaluation work on various FR cycle system concepts, following the design work, in the 1st phase of the JNC's 'Feasibility Study on Commercialized Fast Reactor Cycle System (the F/S)' (from 1999 to March 2001). The purpose of this characteristic evaluation is to reveal the performance of candidate FR cycle systems. For this synthetic estimation, six viewpoints, such as Economics, Effective utilization of uranium resource, Reduction of environmental impact, Safety, Proliferation resistance, and Technological feasibility, are selected. In addition, aiming at the practical use in phase 2, we examined an application to FBR research and development of cost benefit analysis method used for the policy evaluation. Furthermore, long-term nuclear material mass flow was analyzed and the scenario of 'FBR application for the hydrogen production' is proposed, considering how FBR would be utilized for the 21st century. And, a database including the various documents and data used for evaluation was constructed. (author)

  12. Dimensioning BCH codes for coherent DQPSK systems with laser phase noise and cycle slips

    DEFF Research Database (Denmark)

    Leong, Miu Yoong; Larsen, Knud J.; Jacobsen, Gunnar

    2014-01-01

    Forward error correction (FEC) plays a vital role in coherent optical systems employing multi-level modulation. However, much of coding theory assumes that additive white Gaussian noise (AWGN) is dominant, whereas coherent optical systems have significant phase noise (PN) in addition to AWGN...... approach for a target post-FEC BER of 10-5. Codes dimensioned with our bivariate binomial model meet the target within 0.2-dB signal-to-noise ratio....

  13. Experimental Studies of Phase Change and Microencapsulated Phase Change Materials in a Cold Storage/Transportation System with Solar Driven Cooling Cycle

    Directory of Open Access Journals (Sweden)

    Lin Zheng

    2017-11-01

    Full Text Available The paper presents the different properties of phase change material (PCM and Microencapsulated phase change material (MEPCM employed to cold storage/transportation system with a solar-driven cooling cycle. Differential Scanning Calorimeter (DSC tests have been performed to analyze the materials enthalpy, melting temperature range, and temperature range of solidification. KD2 Pro is used to test the thermal conductivities of phase change materials slurry and the results were used to compare the materials heat transfer performance. The slurry flow characteristics of MEPCM slurry also have been tested. Furthermore, in order to analyze the improvement effect on stability, the stability of MEPCM slurry with different surfactants have been tested. The researches of the PCM and MEPCM thermal properties revealed a more prospective application for phase change materials in energy storage/transportation systems. The study aims to find the most suitable chilling medium to further optimize the design of the cold storage/transportation systems with solar driven cooling cycles.

  14. Effect of exercise on the pulmonary system in proliferative phase of menstrual cycle in a group of perimenopausal women

    Directory of Open Access Journals (Sweden)

    Amrith Pakkala

    2014-01-01

    Full Text Available Background: Hormonal levels influence dynamic lung function parameters. Significant increase in both progesterone (37% and estradiol (13.5%; where as, no change in plasma follicle stimulating hormone (FSH and luteinizing hormone (LH was observed in exercising women in previous studies. Therefore, this study was intended to see the limitations of the pulmonary system in adaptability to exercise in proliferative phase of menstrual cycle in perimenopausal women. Material and Methods: The present study was conducted as a part of cardiopulmonary efficiency studies on two groups of nonathletes (n = 10 and athletes (n = 10 comparable in age and sex. Menstrual history was ascertained to confirm proliferative phase of menstrual cycle. Dynamic lung functions were measured in both groups before exercise and immediately after exercise. Results: It was observed that exercise per se does not cause a statistically significant change in dynamic lung function parameters maximum mid-expiratory flow (MMEF, peak expiratory flow rate (PEFR, and MEF 25-75% in either of the groups. Conclusion: This finding supports the hypothesis that the respiratory system is not normally the most limiting factor in the delivery of oxygen even under the predominant influence of estrogen in proliferative phase, which is further accentuated by exercise.

  15. Modeling Two-Phase Flow and Vapor Cycles Using the Generalized Fluid System Simulation Program

    Science.gov (United States)

    Smith, Amanda D.; Majumdar, Alok K.

    2017-01-01

    This work presents three new applications for the general purpose fluid network solver code GFSSP developed at NASA's Marshall Space Flight Center: (1) cooling tower, (2) vapor-compression refrigeration system, and (3) vapor-expansion power generation system. These systems are widely used across engineering disciplines in a variety of energy systems, and these models expand the capabilities and the use of GFSSP to include fluids and features that are not part of its present set of provided examples. GFSSP provides pressure, temperature, and species concentrations at designated locations, or nodes, within a fluid network based on a finite volume formulation of thermodynamics and conservation laws. This paper describes the theoretical basis for the construction of the models, their implementation in the current GFSSP modeling system, and a brief evaluation of the usefulness of the model results, as well as their applicability toward a broader spectrum of analytical problems in both university teaching and engineering research.

  16. An Advanced Rapid Cycling CO2 and H2O Control System for PLSS, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — NASA's planned future missions set stringent demands on the design of the Portable Life Support Systems (PLSS) used to cool the astronaut and provide them with air....

  17. An Advanced Rapid Cycling CO2 and H2O Control System for PLSS, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — NASA's planned future missions set stringent demands on the design of the Portable Life Support Systems (PLSS), requiring dramatic reductions in weight, decreased...

  18. Energy Conversion Alternatives Study (ECAS), General Electric Phase 1. Volume 2: Advanced energy conversion systems. Part 1: Open-cycle gas turbines

    Science.gov (United States)

    Brown, D. H.; Corman, J. C.

    1976-01-01

    Ten energy conversion systems are defined and analyzed in terms of efficiency. These include: open-cycle gas turbine recuperative; open-cycle gas turbine; closed-cycle gas turbine; supercritical CO2 cycle; advanced steam cycle; liquid metal topping cycle; open-cycle MHD; closed-cycle inert gas MHD; closed-cycle liquid metal MHD; and fuel cells. Results are presented.

  19. Limit cycles in quantum systems

    Energy Technology Data Exchange (ETDEWEB)

    Niemann, Patrick

    2015-04-27

    In this thesis we investigate Limit Cycles in Quantum Systems. Limit cycles are a renormalization group (RG) topology. When degrees of freedom are integrated out, the coupling constants flow periodically in a closed curve. The presence of limit cycles is restricted by the necessary condition of discrete scale invariance. A signature of discrete scale invariance and limit cycles is log-periodic behavior. The first part of this thesis is concerned with the study of limit cycles with the similarity renormalization group (SRG). Limit cycles are mainly investigated within conventional renormalization group frameworks, where degrees of freedom, which are larger than a given cutoff, are integrated out. In contrast, in the SRG potentials are unitarily transformed and thereby obtain a band-diagonal structure. The width of the band structure can be regarded as an effective cutoff. We investigate the appearance of limit cycles in the SRG evolution. Our aim is to extract signatures as well as the scaling factor of the limit cycle. We consider the 1/R{sup 2}-potential in a two-body system and a three-body system with large scattering lengths. Both systems display a limit cycle. Besides the frequently used kinetic energy generator we apply the exponential and the inverse generator. In the second part of this thesis, Limit Cycles at Finite Density, we examine the pole structure of the scattering amplitude for distinguishable fermions at zero temperature in the medium. Unequal masses and a filled Fermi sphere for each fermion species are considered. We focus on negative scattering lengths and the unitary limit. The properties of the three-body spectrum in the medium and implications for the phase structure of ultracold Fermi gases are discussed.

  20. Feasibility study on commercialized fast reactor cycle systems. (1) Current status of the phase-II study

    International Nuclear Information System (INIS)

    Sagayama, Yutaka

    2005-01-01

    A feasibility study on commercialized fast reactors including related nuclear fuel cycle systems has been started from Japanese fiscal year 1999 by a Japanese joint project team of Japan Nuclear Cycle Development Institute and the Japan Atomic Power Company. This project aims at elucidating prominent fast reactor cycle systems that will respond to various needs of society in the future, together with economic competitiveness as future electricity supply systems. Challenging technology goals for the fast reactor cycle systems were defined in five targets: safety, economic competitiveness, reduction of environmental burden, efficient utilization of nuclear fuel resources and enhancement of nuclear non-proliferation. As the results of the feasibility study up to now, it is confirmed as the interim results that the combination of sodium-cooled fast reactors with oxide fuels, advanced aqueous reprocessing and simplified pellet fuel fabrication is highly suited to the development targets. The cost would be highly reduced by the adoption of innovative technologies, which feasibility is relatively clear and some R and D issues are now under progress. (author)

  1. GASCON and MHDGAS: FORTRAN IV computer codes for calculating gas and condensed-phase compositions in the coal-fired open-cycle MHD system

    Energy Technology Data Exchange (ETDEWEB)

    Blackburn, P E

    1977-12-01

    Fortran IV computer codes have been written to calculate the equilibrium partial pressures of the gaseous phase and the quantity and composition of the condensed phases in the open-cycle MHD system. The codes are based on temperature-dependent equilibrium constants, mass conservation, the mass action law, and assumed ideal solution of compounds in each of two condensed phases. It is assumed that the phases are an oxide-silicate phase and a sulfate-carbonate-hydroxide phase. Calculations are iterated for gas and condensate concentrations while increasing or decreasing the total moles of elements, but keeping mole ratios constant, to achieve the desired total pressure. During iteration the oxygen partial pressure is incrementally changed. The decision to increase or decrease the oxygen pressure in this process depends on comparison of the oxygen content calculated in the gas and condensate phases with the initial amount of oxygen in the ash, coal, seed, and air. This process, together with a normalization step, allows the elements to converge to their initial quantities. Two versions of the computer code have been written. GASCON calculates the equilibrium gas partial pressures and the quantity and composition of the condensed phases in steps of thirteen temperature and pressure combinations in which the condensate is removed after each step, simulating continuous slag removal from the MHD system. MHDGAS retains the condensate for each step, simulating flow of condensate (and gas) through the MHD system.

  2. Ignition assist systems for direct-injected, diesel cycle, medium-duty alternative fuel engines: Final report phase 1

    Energy Technology Data Exchange (ETDEWEB)

    Chan, A.K.

    2000-02-23

    This report is a summary of the results of Phase 1 of this contract. The objective was to evaluate the potential of assist technologies for direct-injected alternative fuel engines vs. glow plug ignition assist. The goal was to demonstrate the feasibility of an ignition system life of 10,000 hours and a system cost of less than 50% of the glow plug system, while meeting or exceeding the engine thermal efficiency obtained with the glow plug system. There were three tasks in Phase 1. Under Task 1, a comprehensive review of feasible ignition options for DING engines was completed. The most promising options are: (1) AC and the ''SmartFire'' spark, which are both long-duration, low-power (LDLP) spark systems; (2) the short-duration, high-power (SDHP) spark system; (3) the micropilot injection ignition; and (4) the stratified charge plasma ignition. Efforts concentrated on investigating the AC spark, SmartFire spark, and short-duration/high-power spark systems. Using proprietary pricing information, the authors predicted that the commercial costs for the AC spark, the short-duration/high-power spark and SmartFire spark systems will be comparable (if not less) to the glow plug system. Task 2 involved designing and performing bench tests to determine the criteria for the ignition system and the prototype spark plug for Task 3. The two most important design criteria are the high voltage output requirement of the ignition system and the minimum electrical insulation requirement for the spark plug. Under Task 3, all the necessary hardware for the one-cylinder engine test was designed. The hardware includes modified 3126 cylinder heads, specially designed prototype spark plugs, ignition system electronics, and parts for the system installation. Two 3126 cylinder heads and the SmartFire ignition system were procured, and testing will begin in Phase 2 of this subcontract.

  3. Cell-cycle phase specificity of chloroethylnitrosoureas

    International Nuclear Information System (INIS)

    Linfoot, P.A.

    1986-01-01

    Although the cancer chemotherapeutic agent 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) is considered a non-cell cycle phase specific drug, it has been shown to produce differential cell killing in G 1 , S, and G 2 /M phase cells, with S phase cells appearing relatively resistant. Studies of cell cycle phase specific cell killing produced by nitrosoureas with different chemical reactivities, clearly indicated that the ability of compounds to cross-link DNA was important in determining their phase specificity. Cells that lacked guanine O 6 -alkytransferase activity showed similar patterns of BCNU phase specificity regardless of their intrinsic sensitivity to BCNU. DNA inter-strand cross-linking, as measured by alkaline elution, was similar in cells exposed to BCNU in G 1 or S phase. 3 H [1-chloroethyl-1nitrosourea] binding to DNA was the same in G 1 , S and G 2 /M phase cells indicating that phase-specific differences in drug uptake and intracellular drug dose were not responsible for phase specific cell kill. These studies suggest that cross-link lesions, other than DNA inter-strand cross-links, and/or effects on DNA repair, other than guanine O 6 -alkyltransferase, are additional important determinants of BCNU phase specific cell killing

  4. Luteal phase support for assisted reproduction cycles

    NARCIS (Netherlands)

    Linden, M. van der; Buckingham, K.; Farquhar, C.; Kremer, J.A.M.; Metwally, M.

    2015-01-01

    BACKGROUND: Progesterone prepares the endometrium for pregnancy by stimulating proliferation in response to human chorionic gonadotropin(hCG) produced by the corpus luteum. This occurs in the luteal phase of the menstrual cycle. In assisted reproduction techniques(ART), progesterone and/or hCG

  5. Luteal phase support for assisted reproduction cycles

    NARCIS (Netherlands)

    Linden, M. Van der; Buckingham, K.; Farquhar, C.; Kremer, J.A.M.; Metwally, M.

    2011-01-01

    BACKGROUND: Progesterone prepares the endometrium for pregnancy by stimulating proliferation in response to human chorionic gonadotropin (hCG), which is produced by the corpus luteum. This occurs in the luteal phase of the menstrual cycle. In assisted reproduction techniques (ART) the progesterone

  6. A Geometry-Based Cycle Slip Detection and Repair Method with Time-Differenced Carrier Phase (TDCP for a Single Frequency Global Position System (GPS + BeiDou Navigation Satellite System (BDS Receiver

    Directory of Open Access Journals (Sweden)

    Chuang Qian

    2016-12-01

    Full Text Available As the field of high-precision applications based on carriers continues to expand, the development of low-cost, small, modular receivers and their application in diverse scenarios and situations with complex data quality has increased the requirements of carrier-phase data preprocessing. A new geometry-based cycle slip detection and repair method based on Global Position System (GPS + BeiDou Navigation Satellite System (BDS is proposed. The method uses a Time-differenced Carrier Phase (TDCP model, which eliminates the Inner-System Bias (ISB between GPS and BDS, and it is conducive to the effective combination of GPS and BDS. It avoids the interference of the noise of the pseudo-range with cycle slip detection, while the cycle slips are preserved as integers. This method does not limit the receiver frequency number, and it is applicable to single-frequency data. The process is divided into two steps to detect and repair cycle slip. The first step is cycle slip detection, using the Improved Local Analysis Method (ILAM to find satellites that have cycle slips; The second step is to repair the cycle slips, including estimating the float solution of changes in ambiguities at the satellites that have cycle slips with the least squares method and the integer solution of the cycle slips by rounding. In the process of rounding, in addition to the success probability, a decimal test is carried out to validate the result. Finally, experiments with filed test data are carried out to prove the effectiveness of this method. The results show that the detectable cycle slips number with GPS + BDS is much greater than that with GPS. The method can also detect the non-integer outliers while fixing the cycle slip. The maximum decimal bias in repair is less than that with GPS. It implies that this method takes full advantages of multi-system.

  7. Nuclear fuel cycle system analysis

    International Nuclear Information System (INIS)

    Ko, W. I.; Kwon, E. H.; Kim, S. G.; Park, B. H.; Song, K. C.; Song, D. Y.; Lee, H. H.; Chang, H. L.; Jeong, C. J.

    2012-04-01

    The nuclear fuel cycle system analysis method has been designed and established for an integrated nuclear fuel cycle system assessment by analyzing various methodologies. The economics, PR(Proliferation Resistance) and environmental impact evaluation of the fuel cycle system were performed using improved DB, and finally the best fuel cycle option which is applicable in Korea was derived. In addition, this research is helped to increase the national credibility and transparency for PR with developing and fulfilling PR enhancement program. The detailed contents of the work are as follows: 1)Establish and improve the DB for nuclear fuel cycle system analysis 2)Development of the analysis model for nuclear fuel cycle 3)Preliminary study for nuclear fuel cycle analysis 4)Development of overall evaluation model of nuclear fuel cycle system 5)Overall evaluation of nuclear fuel cycle system 6)Evaluate the PR for nuclear fuel cycle system and derive the enhancement method 7)Derive and fulfill of nuclear transparency enhancement method The optimum fuel cycle option which is economical and applicable to domestic situation was derived in this research. It would be a basis for establishment of the long-term strategy for nuclear fuel cycle. This work contributes for guaranteeing the technical, economical validity of the optimal fuel cycle option. Deriving and fulfillment of the method for enhancing nuclear transparency will also contribute to renewing the ROK-U.S Atomic Energy Agreement in 2014

  8. Investigation/evaluation of water cooled fast reactor in the feasibility study on commercialized fast reactor cycle systems. Intermediate evaluation of phase-II study

    International Nuclear Information System (INIS)

    Kotake, Syoji; Nishikawa, Akira

    2005-01-01

    Feasibility study on commercialized fast reactor cycle systems aims at investigation and evaluation of FBR design requirement's attainability, operation and maintenance, and technical feasibility of the candidate system. Development targets are 1) ensuring safety, 2) economic competitiveness, 3) efficient utilization of resources, 4) reduction of environmental load and 5) enhancement of nuclear non-proliferation. Based on the selection of the promising concepts in the first phase, conceptual design for the plant system has proceeded with the following plant system: a) sodium cooled reactors at large size and medium size module reactors, b) a lead-bismuth cooled medium size reactor, c) a helium gas cooled large size reactor and d) a BWR type large size FBR. Technical development and feasibility has been assessed and the study considers the need of respective key technology development for the confirmation of the feasibility study. (T. Tanaka)

  9. Multidimensional evaluation on FR cycle systems

    International Nuclear Information System (INIS)

    Nakai, Ryodai; Fujii, Sumio; Takakuma, Katsuyuki; Katoh, Atsushi; Ono, Kiyoshi; Ohtaki, Akira; Shiotani, Hiroki

    2004-01-01

    This report explains some results of the multidimensional evaluation on various fast reactor cycle system concepts from an interim report of the 2nd phase of ''Feasibility Study on Commercialized FR Cycle System''. This method is designed to give more objective and more quantitative evaluations to clarify commercialized system candidate concepts. Here we brief current evaluation method from the five viewpoints of safety, economy, environment, resource and non-proliferation, with some trial evaluation results for some cycles consist of promising technologies in reactor, core and fuel, reprocessing and fuel manufacture. Moreover, we describe FR cycle deployment scenarios which describe advantages and disadvantages of the cycles from the viewpoints of uranium resource and radioactive waste based on long-term nuclear material mass flow analyses and advantages of the deployment of FR cycle itself from the viewpoints of the comparison with alternative power supplies as well as cost and benefit. (author)

  10. LIFE CYCLE OF INFORMATION SYSTEMS

    Directory of Open Access Journals (Sweden)

    Y. S. Sennik

    2015-01-01

    Full Text Available This work is a generalization of the theoretical propositions related to the life cycle of information systems. There was given the definition of the life cycle, specify which items you should include every step of the cycle. Describes the methodology division of the life cycle on the main stage, including methodology Rational Unified Process. The description of the fundamental standards in this area. Special attention was paid to the work of the basic life cycle models. It was carried out their comparative characteristics. On the basis of the theoretical propositions, it was concluded that the preferred model of the life cycle for the corporate network is a spiral model and the use of international standards in the life cycle saves a lot of effort, time and material resources.

  11. Potential benefits of saturation cycle with two-phase refrigerant injection

    International Nuclear Information System (INIS)

    Lee, Hoseong; Hwang, Yunho; Radermacher, Reinhard; Chun, Ho-Hwan

    2013-01-01

    In this paper, a saturation cycle is proposed to enhance a vapor compression cycle performance by reducing thermodynamic losses associated with single phase gas compression and isenthalpic expansion. In order to approach the saturation cycle, a two-phase refrigerant injection technique is applied to the multi-stage cycle. This multi-stage cycle with different options is modeled, and its performance is evaluated under ASHRAE standard operating conditions for air conditioning systems. Moreover, the two-phase refrigerant injection cycle is compared with the typical vapor injection cycle which is utilizing the internal heat exchanger or the flash tank. Low GWP refrigerants are applied to this two-phase refrigerant injection cycle. In terms of the COP and its improvement, R123 has a higher potential than any other refrigerants in the multi-stage cycle. Lastly, practical ideas realizing the saturation cycle are discussed such as multi-stage phase separator, phase separator with helical structure inside, and injection location of the compressor. -- Highlights: • A saturation cycle is proposed to enhance the vapor compression cycle performance. • Two-phase refrigerant injection technique is applied to the multi-stage cycle. • Modeling results of the proposed cycle show the significant performance improvement. • Low GWP refrigerants are applied and R123 shows the highest performance. • New parameters, α and ε, are used to show the potential of the saturation cycle

  12. PROJECT GOVERNANCE – PHASES AND LIFE CYCLE

    Directory of Open Access Journals (Sweden)

    Robbert Titus DEENEN

    2007-01-01

    Full Text Available When talking about projects, the barrier is clear: successful and failed. Some fail due to different reasons, but lack of good project and risk management played a large part. Others succeed largely because of the rigorous and disciplined application of good project practices. But both groups illustrate many points that underline and demonstrate important concepts applicable to current projects. Systematic application of good methods leads to successful outcomes in projects of all types. All projects are fundamentally dependent on people, and human beings are not very different today than we were hundreds, or even thousands, of years ago. This paper uncovers main elements in projects area such as the concepts and governance of projects, with an underline of the main characteristics and the projects phases and life cycle that erase the uncertainty that joins all the projects built at any time.

  13. The fuel cycle scoping system

    International Nuclear Information System (INIS)

    Dooley, G.D.; Malone, J.P.

    1986-01-01

    The Fuel Cycle Scoping System (FCSS) was created to fill the need for a scoping tool which provides the utilities with the ability to quickly evaluate alternative fuel management strategies, tails assay choices, fuel fabrication quotes, fuel financing alternatives, fuel cycle schedules, and other fuel cycle perturbations. The FCSS was specifically designed for PC's that support dBASE-III(TM), a relational data base software system by Ashton-Tate. However, knowledge of dBASE-III is not necessary in order to utilize the FCSS. The FCSS is menu driven and can be utilized as a teaching tool as well as a scoping tool

  14. Management system and organizational life cycle: A qualitative study

    OpenAIRE

    Selma Zone Fekih Ahmed

    2013-01-01

    This research deals with the importance of the components of the management system according to the phases of organizational life cycle. The goal of our research is to provide the theoretical reflection on the life cycle of the organization and to shed light on the components of the management system for each phase. The conceptual analysis shows that the management system is made up of its three components: ethics, mode of functioning and procedure of regulation. The organizational life cycle...

  15. ITER fuel cycle systems layout

    International Nuclear Information System (INIS)

    Kveton, O.K.

    1990-10-01

    The ITER fuel cycle building (FCB) will contain the following systems: fuel purification - permeator based; fuel purification - molecular sieves; impurity treatment; waste water storage and treatment; isotope separation; waste water tritium extraction; tritium extraction from solid breeder; tritium extraction from test modules; tritium storage, shipping and receiving; tritium laboratory; atmosphere detritiation systems; fuel cycle control centre; tritiated equipment maintenance space; control maintenance space; health physics laboratory; access, access control and facilities. The layout of the FCB and the requirements for these systems are described. (10 figs.)

  16. Cell cycle phases in the unequal mother/daughter cell cycles of Saccharomyces cerevisiae.

    Science.gov (United States)

    Brewer, B J; Chlebowicz-Sledziewska, E; Fangman, W L

    1984-11-01

    During cell division in the yeast Saccharomyces cerevisiae mother cells produce buds (daughter cells) which are smaller and have longer cell cycles. We performed experiments to compare the lengths of cell cycle phases in mothers and daughters. As anticipated from earlier indirect observations, the longer cell cycle time of daughter cells is accounted for by a longer G1 interval. The S-phase and the G2-phase are of the same duration in mother and daughter cells. An analysis of five isogenic strains shows that cell cycle phase lengths are independent of cell ploidy and mating type.

  17. Energy Conversion Alternatives Study (ECAS), Westinghouse phase 1. Volume 6: Closed-cycle gas turbine systems. [energy conversion efficiency in electric power plants

    Science.gov (United States)

    Amos, D. J.; Fentress, W. K.; Stahl, W. F.

    1976-01-01

    Both recuperated and bottomed closed cycle gas turbine systems in electric power plants were studied. All systems used a pressurizing gas turbine coupled with a pressurized furnace to heat the helium for the closed cycle gas turbine. Steam and organic vapors are used as Rankine bottoming fluids. Although plant efficiencies of over 40% are calculated for some plants, the resultant cost of electricity was found to be 8.75 mills/MJ (31.5 mills/kWh). These plants do not appear practical for coal or oil fired plants.

  18. Airbreathing combined cycle engine systems

    Science.gov (United States)

    Rohde, John

    1992-01-01

    The Air Force and NASA share a common interest in developing advanced propulsion systems for commercial and military aerospace vehicles which require efficient acceleration and cruise operation in the Mach 4 to 6 flight regime. The principle engine of interest is the turboramjet; however, other combined cycles such as the turboscramjet, air turborocket, supercharged ejector ramjet, ejector ramjet, and air liquefaction based propulsion are also of interest. Over the past months careful planning and program implementation have resulted in a number of development efforts that will lead to a broad technology base for those combined cycle propulsion systems. Individual development programs are underway in thermal management, controls materials, endothermic hydrocarbon fuels, air intake systems, nozzle exhaust systems, gas turbines and ramjet ramburners.

  19. Rankine cycle system and method

    Science.gov (United States)

    Ernst, Timothy C.; Nelson, Christopher R.

    2014-09-09

    A Rankine cycle waste heat recovery system uses a receiver with a maximum liquid working fluid level lower than the minimum liquid working fluid level of a sub-cooler of the waste heat recovery system. The receiver may have a position that is physically lower than the sub-cooler's position. A valve controls transfer of fluid between several of the components in the waste heat recovery system, especially from the receiver to the sub-cooler. The system may also have an associated control module.

  20. APT, The Phase I tool for HST Cycle 12

    Science.gov (United States)

    Blacker, Brett S.; Bertch, Maria; Curtis, Gary; Douglas, Robert E., Jr.; Krueger, Anthony P.

    2002-12-01

    In the continuing effort to streamline our systems and improve service to the science community, the Space Telescope Science Institute (STScI) is developing and releasing, APT The Astronomer’s Proposal Tool as the new interface for Hubble Space Telescope (HST) Phase I and Phase II proposal submissions for HST Cycle 12. APT, was formerly called the Scientist’s Expert Assistant (SEA), which started as a prototype effort to try and bring state of the art technology, more visual tools and power into the hands of proposers so that they can optimize the scientific return of their programs as well as HST. Proposing for HST and other missions, consists of requesting observing time and/or archival research funding. This step is called Phase I, where the scientific merit of a proposal is considered by a community based peer-review process. Accepted proposals then proceed thru Phase II, where the observations are specified in sufficient detail to enable scheduling on the telescope. In this paper, we will present our concept and implementation plans for our Phase I development and submission tool, APT. More importantly, we will go behind the scenes and discuss why it’s important for the Science Policies Division (SPD) and other groups at the STScI to have a new submission tool and submission output products. This paper is an update of the status of the HST Phase I Proposal Processing System that was described in the published paper “A New Era for HST Phase I Development and Submission.”

  1. Life cycles of energetic systems

    International Nuclear Information System (INIS)

    Adnot, Jerome; Marchio, Dominique; Riviere, Philippe; Duplessis, B.; Rabl, A.; Glachant, M.; Aggeri, F.; Benoist, A.; Teulon, H.; Daude, J.

    2012-01-01

    This collective publication aims at being a course for students in engineering of energetic systems, i.e. at learning how to decide to accept or discard a project, to select the most efficient system, to select the optimal system, to select the optimal combination of systems, and to classify independent systems. Thus, it presents methods to analyse system life cycle from an energetic, economic and environmental point of view, describes how to develop an approach to the eco-design of an energy consuming product, how to understand the importance of hypotheses behind abundant and often contradicting publicised results, and to be able to criticise or to put in perspective one's own analysis. The first chapters thus recall some aspects of economic calculation, introduce the assessment of investment and exploitation costs of energetic systems, describe how to assess and internalise environmental costs, present the territorial carbon assessment, discuss the use of the life cycle assessment, and address the issue of environmental management at a product scale. The second part proposes various case studies: an optimal fleet of thermal production of electric power, the eco-design of a refrigerator, the economic and environmental assessment of wind farms

  2. Development of FBR cycle data base system

    International Nuclear Information System (INIS)

    Kubota, Sadae; Ohtaki, Akira; Hirao, Kazuhiro

    2002-06-01

    In the 'Feasibility Study on Commercialized Fast Reactor Cycle System (F/S)'. scenario evaluations, cost-benefit evaluations and system characteristic evaluations to show significance of the Fast Breeder Reactor (FBR) cycle system introduction concretely are performed in parallel with a design study for FBR plants, reprocessing systems and fabrication systems. In these evaluations, informations such as economic prospects, prospects for supply and demand of resources and a progress of engineering development are used in addition to design information. This report explains a FBR Cycle Database in order to carry out management and search of various design information and the relating information. The prototype system of the database was completed in the 2000 fiscal year, and the problem of the user number restriction of the prototype system has been improved by Web-ization in the 2001 fiscal year. About 7,000 data are stored in this data base (as of the end of March, 2002). The expansion of user etc., and the continuation of input work of various evaluation information will be carried out, in the phase 2 of F/S. (author)

  3. Segmentation and classification of cell cycle phases in fluorescence imaging.

    Science.gov (United States)

    Ersoy, Ilker; Bunyak, Filiz; Chagin, Vadim; Cardoso, M Christina; Palaniappan, Kannappan

    2009-01-01

    Current chemical biology methods for studying spatiotemporal correlation between biochemical networks and cell cycle phase progression in live-cells typically use fluorescence-based imaging of fusion proteins. Stable cell lines expressing fluorescently tagged protein GFP-PCNA produce rich, dynamically varying sub-cellular foci patterns characterizing the cell cycle phases, including the progress during the S-phase. Variable fluorescence patterns, drastic changes in SNR, shape and position changes and abundance of touching cells require sophisticated algorithms for reliable automatic segmentation and cell cycle classification. We extend the recently proposed graph partitioning active contours (GPAC) for fluorescence-based nucleus segmentation using regional density functions and dramatically improve its efficiency, making it scalable for high content microscopy imaging. We utilize surface shape properties of GFP-PCNA intensity field to obtain descriptors of foci patterns and perform automated cell cycle phase classification, and give quantitative performance by comparing our results to manually labeled data.

  4. Transportation Life Cycle Assessment (LCA) Synthesis, Phase II

    Science.gov (United States)

    2018-04-24

    The Transportation Life Cycle Assessment (LCA) Synthesis includes an LCA Learning Module Series, case studies, and analytics on the use of the modules. The module series is a set of narrated slideshows on topics related to environmental LCA. Phase I ...

  5. Solar Cycle Phase Dependence of Supergranular Fractal Dimension

    Indian Academy of Sciences (India)

    Solar Cycle Phase Dependence of Supergranular Fractal Dimension ... NIE Institute of Technology, Mysore, India. ... This means that each accepted article is being published immediately online with DOI and article citation ID with starting page ...

  6. CORE COMPETENCIES AND PHASES OF THE ORGANIZATIONAL LIFE CYCLE

    OpenAIRE

    Ahmed, Selma Zone Fekih; Koubaa, Manel Belguith

    2013-01-01

    Organizations evolve according to well-defined phases during which it must raise some competencies more than others. This study discusses the importance of core competencies according to the phases of the life cycle of the organization. In this research, we mobilize the core competencies approach to explore the competence required at each stage of the organizational life cycle. The quantitative study of 50 Tunisian companies operating in the food sector shows that the importance of core ...

  7. Preliminary Studies of Two-Phase Reactive Process of Sodium-CO2 in S-CO2 Power Conversion Cycle Coupled to SFR System

    International Nuclear Information System (INIS)

    Jung, Hwa Young; Ahn, Yoon Han; Lee, You Ho; Lee, Jeong Ik

    2013-01-01

    As a competing alternative to the steam Rankine cycle, the supercritical CO 2 (S-CO 2 ) Brayton cycle has been highlighted due to its high thermal efficiency, compact turbomachinery and heat exchangers sizes, and the reduced risk of SWRs. While the reduced risk of an SWR is considered as the one of most pronounced benefits of S-CO 2 Brayton cycle, there is still an interaction problem between liquid sodium and CO 2 . Although the chemical interaction between liquid sodium and CO 2 demonstrates less serious potential risks than those of a SWR, the Na/CO 2 interaction should be understood to evaluate safety and reliability of Intermediate Heat eXchanger (IHX). A noticeable characteristic of the reaction environment is that there is a large pressure difference between the liquid sodium and CO 2 side by about 1 and 200 bar, respectively. This would imply that the presence of a micro-crack in a heat exchanger tube will cause a high-pressure leak of CO 2 into liquid sodium side. Although the Na/CO 2 interaction may play an important role in the safety of the SFR reactor system, there has not yet been any research on understanding Na/CO 2 reaction by leakage through IHX. For this problem, the Korea Advanced Institute of Science and Technology (KAIST) research team is studying the mechanism of CO 2 leakage and Na/CO 2 interaction in more details. The KAIST research team developed the MATLAB code, KAIST H XD, which can be used to design and evaluate performance of a heat exchanger of an S-CO 2 cycle. The size of heat exchanger and the amount of CO 2 in the cycle are calculated from the KAIST H XD code to estimate the amount of reaction products in Na/CO 2 interaction as well as liquid sodium

  8. Structural-Phase Transformations of CuZn Alloy Under Thermal-Impact Cycling

    Science.gov (United States)

    Potekaev, A. I.; Chaplygina, A. A.; Kulagina, V. V.; Chaplygin, P. A.; Starostenkov, M. D.; Grinkevich, L. S.

    2017-02-01

    Using the Monte Carlo method, special features of structural - phase transformations in β-brass are investigated during thermal impact using thermal cycling as an example (a number of successive order - disorder and disorder - order phase transitions in the course of several heating - cooling cycles). It is shown that a unique hysteresis is observed after every heating and cooling cycle, whose presence indicates irreversibility of the processes, which suggests a difference in the structural - phase states both in the heating and cooling stages. A conclusion is drawn that the structural - phase transformations in the heating and cooling stages occur within different temperature intervals, where the thermodynamic stimuli of one or the other structural - phase state are low. This is also demonstrated both in the plots of configurational energy, long- and short-range order parameter, atomic structure variations, and structural - phase state distributions. Simultaneously, there coexist ordered and disordered phases and a certain collection of superstructure domains. This implies the presence of low - stability states in the vicinity of the order - disorder phase transition. The results of investigations demonstrate that the structural - phase transitions within two successive heating and cooling cycles at the same temperature are different in both stages. These changes, though not revolutionary, occur in every cycle and decrease with the increasing cycle number. In fact, the system undergoes training with a tendency towards a certain sequence of structural - phase states.

  9. Menstrual cycle phase does not predict political conservatism.

    Science.gov (United States)

    Scott, Isabel M; Pound, Nicholas

    2015-01-01

    Recent authors have reported a relationship between women's fertility status, as indexed by menstrual cycle phase, and conservatism in moral, social and political values. We conducted a survey to test for the existence of a relationship between menstrual cycle day and conservatism. 2213 women reporting regular menstrual cycles provided data about their political views. Of these women, 2208 provided information about their cycle date, 1260 provided additional evidence of reliability in self-reported cycle date, and of these, 750 also indicated an absence of hormonal disruptors such as recent hormonal contraception use, breastfeeding or pregnancy. Cycle day was used to estimate day-specific fertility rate (probability of conception); political conservatism was measured via direct self-report and via responses to the "Moral Foundations" questionnaire. We also recorded relationship status, which has been reported to interact with menstrual cycle phase in determining political preferences. We found no evidence of a relationship between estimated cyclical fertility changes and conservatism, and no evidence of an interaction between relationship status and cyclical fertility in determining political attitudes. Our findings were robust to multiple inclusion/exclusion criteria and to different methods of estimating fertility and measuring conservatism. In summary, the relationship between cycle-linked reproductive parameters and conservatism may be weaker or less reliable than previously thought.

  10. Menstrual cycle phase does not predict political conservatism.

    Directory of Open Access Journals (Sweden)

    Isabel M Scott

    Full Text Available Recent authors have reported a relationship between women's fertility status, as indexed by menstrual cycle phase, and conservatism in moral, social and political values. We conducted a survey to test for the existence of a relationship between menstrual cycle day and conservatism. 2213 women reporting regular menstrual cycles provided data about their political views. Of these women, 2208 provided information about their cycle date, 1260 provided additional evidence of reliability in self-reported cycle date, and of these, 750 also indicated an absence of hormonal disruptors such as recent hormonal contraception use, breastfeeding or pregnancy. Cycle day was used to estimate day-specific fertility rate (probability of conception; political conservatism was measured via direct self-report and via responses to the "Moral Foundations" questionnaire. We also recorded relationship status, which has been reported to interact with menstrual cycle phase in determining political preferences. We found no evidence of a relationship between estimated cyclical fertility changes and conservatism, and no evidence of an interaction between relationship status and cyclical fertility in determining political attitudes. Our findings were robust to multiple inclusion/exclusion criteria and to different methods of estimating fertility and measuring conservatism. In summary, the relationship between cycle-linked reproductive parameters and conservatism may be weaker or less reliable than previously thought.

  11. PHASE RELATIONSHIPS OF SOLAR HEMISPHERIC TOROIDAL AND POLOIDAL CYCLES

    Energy Technology Data Exchange (ETDEWEB)

    Muraközy, J., E-mail: murakozy.judit@csfk.mta.hu [Debrecen Heliophysical Observatory (DHO), Konkoly Observatory, Research Centre for Astronomy and Earth Sciences H-4010 Debrecen P.O.B. 30, H-4010 (Hungary)

    2016-08-01

    The solar northern and southern hemispheres exhibit differences in their intensities and time profiles of the activity cycles. The time variation of these properties was studied in a previous article covering the data from Cycles 12–23. The hemispheric phase lags exhibited a characteristic variation: the leading role was exchanged between hemispheres every four cycles. The present work extends the investigation of this variation using the data of Staudacher and Schwabe in Cycles 1–4 and 7–10 as well as Spörer’s data in Cycle 11. The previously observed variation cannot be clearly recognized using the data of Staudacher, Schwabe, and Spörer. However, it is more interesting that the phase lags of the reversals of the magnetic fields at the poles follow the same variations as those of the hemispheric cycles in Cycles 12–23, i.e., one of the hemispheres leads in four cyles and the leading role jumps to the opposite hemisphere in the next four cycles. This means that this variation is a long-term property of the entire solar dynamo mechanism, for both the toroidal and poloidal fields, which hints at an unidentified component of the process responsible for the long-term memory.

  12. Fuel Cycle System Analysis Handbook

    International Nuclear Information System (INIS)

    Piet, Steven J.; Dixon, Brent W.; Gombert, Dirk; Hoffman, Edward A.; Matthern, Gretchen E.; Williams, Kent A.

    2009-01-01

    This Handbook aims to improve understanding and communication regarding nuclear fuel cycle options. It is intended to assist DOE, Campaign Managers, and other presenters prepare presentations and reports. When looking for information, check here. The Handbook generally includes few details of how calculations were performed, which can be found by consulting references provided to the reader. The Handbook emphasizes results in the form of graphics and diagrams, with only enough text to explain the graphic, to ensure that the messages associated with the graphic is clear, and to explain key assumptions and methods that cause the graphed results. Some of the material is new and is not found in previous reports, for example: (1) Section 3 has system-level mass flow diagrams for 0-tier (once-through), 1-tier (UOX to CR=0.50 fast reactor), and 2-tier (UOX to MOX-Pu to CR=0.50 fast reactor) scenarios - at both static and dynamic equilibrium. (2) To help inform fast reactor transuranic (TRU) conversion ratio and uranium supply behavior, section 5 provides the sustainable fast reactor growth rate as a function of TRU conversion ratio. (3) To help clarify the difference in recycling Pu, NpPu, NpPuAm, and all-TRU, section 5 provides mass fraction, gamma, and neutron emission for those four cases for MOX, heterogeneous LWR IMF (assemblies mixing IMF and UOX pins), and a CR=0.50 fast reactor. There are data for the first 10 LWR recycle passes and equilibrium. (4) Section 6 provides information on the cycle length, planned and unplanned outages, and TRU enrichment as a function of fast reactor TRU conversion ratio, as well as the dilution of TRU feedstock by uranium in making fast reactor fuel. (The recovered uranium is considered to be more pure than recovered TRU.) The latter parameter impacts the required TRU impurity limits specified by the Fuels Campaign. (5) Section 7 provides flows for an 800-tonne UOX separation plant. (6) To complement 'tornado' economic uncertainty

  13. Predicting the start and maximum amplitude of solar cycle 24 using similar phases and a cycle grouping

    International Nuclear Information System (INIS)

    Wang Jialong; Zong Weiguo; Le Guiming; Zhao Haijuan; Tang Yunqiu; Zhang Yang

    2009-01-01

    We find that the solar cycles 9, 11, and 20 are similar to cycle 23 in their respective descending phases. Using this similarity and the observed data of smoothed monthly mean sunspot numbers (SMSNs) available for the descending phase of cycle 23, we make a date calibration for the average time sequence made of the three descending phases of the three cycles, and predict the start of March or April 2008 for cycle 24. For the three cycles, we also find a linear correlation of the length of the descending phase of a cycle with the difference between the maximum epoch of this cycle and that of its next cycle. Using this relationship along with the known relationship between the rise-time and the maximum amplitude of a slowly rising solar cycle, we predict the maximum SMSN of cycle 24 of 100.2 ± 7.5 to appear during the period from May to October 2012. (letters)

  14. Thermodynamic sensitivity analysis of a novel trigeneration thermodynamic cycle with two-phase expanders and two-phase compressors

    International Nuclear Information System (INIS)

    Briola, Stefano; Di Marco, Paolo; Gabbrielli, Roberto

    2017-01-01

    A novel Combined Cooling, Heating and Power (CCHP) cycle, operating with two-phase devices for the compression and expansion processes and a single-component wet working fluid, is proposed. A detailed sensitivity analysis of the novel CCHP cycle has been investigated in order to evaluate, in terms of energy performance indicators, its potentiality to serve typical trigenerative tertiary and industrial end-users with different fixed operating temperatures. In general, the novel CCHP cycle is characterized by higher energy performance indicators than a separated energy production system. The comparison between the novel CCHP cycle and several commercialized CCHP systems has been performed in the case studies related to tertiary and industrial end-users. The novel CCHP cycle shows a trigenerative capability in wide ranges of the end-users demands without surplus or deficit of the electric or thermal powers. Furthermore, the maximum allowable capital cost of the whole novel CCHP plant (BEPCC), that will assure the profitability of the investment, is calculated in the tertiary and industrial end-users case studies. For the tertiary end-user, the capital costs of the commercialized CCHP are between the minimum and maximum BEPCC values. On the contrary, for the industrial end-user, they are lower than the minimum and maximum BEPCC values. - Highlights: • Novel CCHP cycle with two-phase expanders and compressors has been conceived. • Novel CCHP cycle has higher performances than a separated energy production system. • Novel CCHP cycle satisfies the user demands in wide ranges without surplus/deficit. • Tertiary user: novel CCHP cycle is competitive against marketed CCHP systems. • Industrial user: novel CCHP cycle is not competitive against marketed CCHP systems.

  15. Phase Control in Nonlinear Systems

    Science.gov (United States)

    Zambrano, Samuel; Seoane, Jesús M.; Mariño, Inés P.; Sanjuán, Miguel A. F.; Meucci, Riccardo

    The following sections are included: * Introduction * Phase Control of Chaos * Description of the model * Numerical exploration of phase control of chaos * Experimental evidence of phase control of chaos * Phase Control of Intermittency in Dynamical Systems * Crisis-induced intermittency and its control * Experimental setup and implementation of the phase control scheme * Phase control of the laser in the pre-crisis regime * Phase control of the intermittency after the crisis * Phase control of the intermittency in the quadratic map * Phase Control of Escapes in Open Dynamical Systems * Control of open dynamical systems * Model description * Numerical simulations and heuristic arguments * Experimental implementation in an electronic circuit * Conclusions and Discussions * Acknowledgments * References

  16. Opportunities for sub-laser-cycle spectroscopy in condensed phase

    International Nuclear Information System (INIS)

    Ivanov, Misha; Smirnova, Olga

    2013-01-01

    Highlights: ► We discuss how sub-cycle attosecond spectroscopy can be extended from gas to condensed phase. ► We show that attosecond streaking measurements can be applied to bound electrons. ► We discuss time-resolving the formation of band structure in laser fields. - Abstract: To a large extent, progress of attosecond spectroscopy in the gas phase has been driven by designing approaches where time-resolution is not limited by the pulse duration. Instead, the time resolution comes from exploiting the sensitivity of electronic response to the oscillations of the electric field in the laser pulse and attosecond control over these oscillations. This paper discusses perspectives and opportunities for transporting the ideas of sub-cycle spectroscopy from gas to condensed phase

  17. Aerospace Systems Monitor, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — Proposal Title: Aerospace Systems Monitor PHASE 1 Technical Abstract: This Phase II STTR project will continue development and commercialization of the Aerospace...

  18. Respiratory functions in asthmatic and normal women during different phases of menstrual cycle

    International Nuclear Information System (INIS)

    Arora, D.B.; Sandhu, P.K.; Dhillon, S.; Arora, A.

    2015-01-01

    Menstrual cycle is an integral part of life of women. There is widespread agreement that changes in the levels of oestrogen and progesterone associated with menstrual cycle also affect different systems of the body besides reproductive system. Levels of oestrogen and progesterone are maximum in the secretory phase and minimum just before the menstruation .Bronchial asthma is one of the commonest chronic respiratory diseases. Premenstrual worsening of asthma symptoms has been reported to affect 33-40% of asthmatic women. This exacerbation of asthma symptoms has been correlated with the oestrogen and progesterone levels. The association between menstrual cycle and lung functions in normal females has also been recognised. The pathophysiology of this process is still not proved. The purpose of our study was to confirm the probable effects of the female hormones on lung functions in normal and asthmatic women in different phases of menstrual cycle and to compare them. Methods: The study was done on 40 normal and 40 asthmatic females in the age group of 15-45 years. Pulmonary function tests were done in three phases of menstrual cycle i.e. follicular, secretory and menstrual in all the subjects. Results: The mean value of lung functions, i.e., FVC, FEV, PEFR, FEF25-75%, FEF 200-1200 were significantly lower in asthmatic females than normal ones (p<0.01) in all three phases. The lung functions of both asthmatic and non-asthmatic females in secretory phase were significantly higher than in menstrual phase (p<0.005). The PFTs in menstrual phase were even lower than the follicular phase (p<0.04). Conclusion: Respiratory parameters of both asthmatic and non-asthmatic women in reproductive age group show significant variation in different phases of menstrual cycle. The smooth muscle relaxant effect of progesterone and probably oestrogen might have contributed to it. The lung function parameters in asthmatics were of lower value compared to normal women. (author)

  19. Serum Thyrotropin and Phase of the Menstrual Cycle

    Directory of Open Access Journals (Sweden)

    Salvatore Benvenga

    2017-09-01

    Full Text Available About one-fifth of patients treated with levothyroxine have serum thyrotropin (TSH above target concentrations but, in approximately 15% of them, the cause of this TSH insufficient normalization remains unknown. We report the cases of two regularly menstruating women with known thyroid disease who had TSH levels consistently >3 mU/L (and sometimes above target levels during mid-cycle, but consistently lower serum levels during the follicular and luteal phases of menstrual cycle. A major TSH release by the thyrotrophs in response to high circulating levels of estradiol (E2 at mid-cycle may increase levels of TSH compared to other phases of the cycle. The increased TSH can be misinterpreted as refractory hypothyroidism if the woman is under L-T4 replacement therapy or as subclinical hypothyroidism if the woman is not. Our findings might have important implications for diagnosis and management of thyroid disease, suggesting to request serum TSH measurements outside of the periovulatory days.

  20. Life-Cycle Models for Survivable Systems

    National Research Council Canada - National Science Library

    Linger, Richard

    2002-01-01

    .... Current software development life-cycle models are not focused on creating survivable systems, and exhibit shortcomings when the goal is to develop systems with a high degree of assurance of survivability...

  1. Interactive Effects of Dopamine Baseline Levels and Cycle Phase on Executive Functions: The Role of Progesterone

    Directory of Open Access Journals (Sweden)

    Esmeralda Hidalgo-Lopez

    2017-07-01

    Full Text Available Estradiol and progesterone levels vary along the menstrual cycle and have multiple neuroactive effects, including on the dopaminergic system. Dopamine relates to executive functions in an “inverted U-shaped” manner and its levels are increased by estradiol. Accordingly, dopamine dependent changes in executive functions along the menstrual cycle have been previously studied in the pre-ovulatory phase, when estradiol levels peak. Specifically it has been demonstrated that working memory is enhanced during the pre-ovulatory phase in women with low dopamine baseline levels, but impaired in women with high dopamine baseline levels. However, the role of progesterone, which peaks in the luteal cycle phase, has not been taken into account previously. Therefore, the main goals of the present study were to extend these findings (i to the luteal cycle phase and (ii to other executive functions. Furthermore, the usefulness of the eye blink rate (EBR as an indicator of dopamine baseline levels in menstrual cycle research was explored. 36 naturally cycling women were tested during three cycle phases (menses–low sex hormones; pre-ovulatory–high estradiol; luteal–high progesterone and estradiol. During each session, women performed a verbal N-back task, as measure of working memory, and a single trial version of the Stroop task, as measure of response inhibition and cognitive flexibility. Hormone levels were assessed from saliva samples and spontaneous eye blink rate was recorded during menses. In the N-back task, women were faster during the luteal phase the higher their progesterone levels, irrespective of their dopamine baseline levels. In the Stroop task, we found a dopamine-cycle interaction, which was also driven by the luteal phase and progesterone levels. For women with higher EBR performance decreased during the luteal phase, whereas for women with lower EBR performance improved during the luteal phase. These findings suggest an important

  2. The feasibility study on commercialized fast reactor cycle system

    International Nuclear Information System (INIS)

    Noda, Hiroshi

    2002-01-01

    The feasibility study on commercialized Fast Reactor cycle system (FS) has been carried out by a joint team with the participation of all parties concerned in Japan since July, 1999. It aims to clarify various perspectives for commercialized fast reactor cycle system and also suggest development strategies to diverse social needs in the 21 st century. The FS consists of several phases. The phase 1 has progressed as planned and the highly feasible candidate concepts with innovative technologies have been screened out among a wide variety of concepts. During the phase 2, approximately five years after the phase 1, the in-depth design studies and engineering scale tests of key technologies are being conducted to verify and validate the feasibility of screened candidate concepts. At the end of the phase 2, a few promising concepts will be selected with their R and D tasks. The paper describes the results of the phase 1, the activities of the phase 2 and the new concept related to the fast reactor fuel cycle focusing on the reduction in environmental burden, which is one of key factors to sustain the nuclear power generation in the 21 st century

  3. Rankine cycle waste heat recovery system

    Science.gov (United States)

    Ernst, Timothy C.; Nelson, Christopher R.

    2014-08-12

    This disclosure relates to a waste heat recovery (WHR) system and to a system and method for regulation of a fluid inventory in a condenser and a receiver of a Rankine cycle WHR system. Such regulation includes the ability to regulate the pressure in a WHR system to control cavitation and energy conversion.

  4. Brayton cycle space power systems

    International Nuclear Information System (INIS)

    Pietsch, A.; Trimble, S.W.; Harper, A.D.

    1985-01-01

    The latest accomplishments in the design and development of the Brayton Isotope Power System (BIPS) for space applications are described, together with a reexamination of the design/cost tradeoffs with respect to current economic parameters and technology status. The results of tests performed on a ground test version of the flight configuration, the workhorse loop, were used to confirm the performance projections made for the flight system. The results of cost-model analysis indicate that the use of the highest attainable power conversion system efficiency will yield the most cost-effective systems. 13 references

  5. Guidance for the application of an assessment methodology for innovative nuclear energy systems. INPRO manual - Physical protection. Vol. 6 of the final report of phase 1 of the International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO)

    International Nuclear Information System (INIS)

    2008-11-01

    The International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO) was initiated in the year 2000, based on a resolution of the IAEA General Conference (GC(44)/RES/21). The main objectives of INPRO are (1) to help to ensure that nuclear energy is available to contribute in fulfilling energy needs in the 21st century in a sustainable manner, (2) to bring together both technology holders and technology users to consider jointly the international and national actions required to achieve desired innovations in nuclear reactors and fuel cycles; and (3) to create a forum to involve all relevant stakeholders that will have an impact on, draw from, and complement the activities of existing institutions, as well as ongoing initiatives at the national and international level. This document follows the guidelines of the INPRO report M ethodology for the assessment of innovative nuclear reactors and fuel cycles, Report of Phase 1B (first part) of the International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO) , IAEA-TECDOC-1434 (2004), together with its previous report G uidance for the evaluation for innovative nuclear reactors and fuel cycles, Report of Phase 1A of the International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO), IAEATECDOC-1362 (2003). This INPRO manual is comprised of an overview volume and eight additional volumes covering the areas of economics (Volume 2), infrastructure (Volume 3), waste management (Volume 4), proliferation resistance (Volume 5), physical protection (Volume 6), environment (Volume 7), safety of reactors (Volume 8), and safety of nuclear fuel cycle facilities (Volume 9). The INPRO Manual for the area of physical protection (Volume 6) provides guidance to the assessor of an INS (innovative nuclear energy system) under a physical protection regime in a country that is planning to install a nuclear power program (or maintaining or enlarging an existing one), and describes the application of the

  6. Phase resetting reveals network dynamics underlying a bacterial cell cycle.

    Science.gov (United States)

    Lin, Yihan; Li, Ying; Crosson, Sean; Dinner, Aaron R; Scherer, Norbert F

    2012-01-01

    Genomic and proteomic methods yield networks of biological regulatory interactions but do not provide direct insight into how those interactions are organized into functional modules, or how information flows from one module to another. In this work we introduce an approach that provides this complementary information and apply it to the bacterium Caulobacter crescentus, a paradigm for cell-cycle control. Operationally, we use an inducible promoter to express the essential transcriptional regulatory gene ctrA in a periodic, pulsed fashion. This chemical perturbation causes the population of cells to divide synchronously, and we use the resulting advance or delay of the division times of single cells to construct a phase resetting curve. We find that delay is strongly favored over advance. This finding is surprising since it does not follow from the temporal expression profile of CtrA and, in turn, simulations of existing network models. We propose a phenomenological model that suggests that the cell-cycle network comprises two distinct functional modules that oscillate autonomously and couple in a highly asymmetric fashion. These features collectively provide a new mechanism for tight temporal control of the cell cycle in C. crescentus. We discuss how the procedure can serve as the basis for a general approach for probing network dynamics, which we term chemical perturbation spectroscopy (CPS).

  7. The Nuclear Fuel Cycle Information System

    International Nuclear Information System (INIS)

    1987-02-01

    The Nuclear Fuel Cycle Information System (NFCIS) is an international directory of civilian nuclear fuel cycle facilities. Its purpose is to identify existing and planned nuclear fuel cycle facilities throughout the world and to indicate their main parameters. It includes information on facilities for uranium ore processing, refining, conversion and enrichment, for fuel fabrication, away-from-reactor storage of spent fuel and reprocessing, and for the production of zirconium metal and Zircaloy tubing. NFCIS currently covers 271 facilities in 32 countries and includes 171 references

  8. Thermodynamic cycles of adsorption desalination system

    International Nuclear Information System (INIS)

    Wu, Jun W.; Hu, Eric J.; Biggs, Mark J.

    2012-01-01

    Highlights: ► Thermodynamic cycles of adsorption desalination (AD) system have been identified all possible evaporator temperature scenarios. ► Temperature of evaporator determines the cycle. ► Higher evaporator temperature leads to higher water production if no cooling is required. -- Abstract: The potential to use waste heat to co-generate cooling and fresh water from saline water using adsorption on silica is attracting increasing attention. A variety of different thermodynamic cycles of such an adsorption desalination (AD) system arise as the temperature of the saline water evaporator is varied relative to temperature of the water used to cool the adsorbent as it adsorbs the evaporated water. In this paper, all these possible thermodynamic cycles are enumerated and analysed to determine their relative performances in terms of specific energy consumption and fresh water productivity.

  9. Experimental demonstrations of organic Rankine cycle waste heat rejection systems

    Science.gov (United States)

    Bland, Timothy J.; Lacey, P. Douglas

    Two phase fluid management is an important factor in the successful design of organic Rankine cycle (ORC) power conversion systems for space applications. The evolution of the heat rejection system approach from a jet condenser, through a rotary jet condenser, to a rotary fluid management device (RFMD) with a surface condenser has been described in a previous paper. Some of the test programs that were used to prove the validity of the selected approach are described.

  10. Evaluation methodology and prospective introduction scenarios of FR cycle systems

    International Nuclear Information System (INIS)

    Fujii, Sumio; Katoh, Atsushi; Sato, Kazujiro

    2003-01-01

    The 21st century society will be facing growing demand of energy, global environmental issues and concerns about fossil fuel exhaustion. In this society, it is essential to seek for a sustainable energy system to solve these energy-related concerns. In order to find ways for solving these problems, 'Feasibility Study on Commercialized FR Cycle System' was launched in 1999 as a joint research project of JNC, electric utilities, JAERI, CRIEPI etc. This project aims to build promising FR cycle technologies for the 21st century. Now, we are in the second phase (JFY 2001-2005) of this project. At the end of the second phase, we will propose promising concepts through applying innovative technologies. We started this Feasibility Study with defining the development target, which ended in five items; safety, economy, environmental burden, resource utilization and nuclear non-proliferation. These items should also serve as basic viewpoints to evaluate achievements of the study. This paper describes how we evaluate FR cycle options to come up with the final promising candidates. This paper also describes a prospective scenario to introduce FR cycle system, which shows how the FR cycle will be replacing existing LWRs by using limited natural uranium resource and spent fuels. (author)

  11. Diagnostic system for combine cycle power plant

    International Nuclear Information System (INIS)

    Shimizu, Yujiro; Nomura, Masumi; Tanaka, Satoshi; Ito, Ryoji; Kita, Yoshiyuki

    2000-01-01

    We developed the Diagnostic System for Combined Cycle Power Plant which enables inexperienced operators as well as experienced operators to cope with abnormal conditions of Combined Cycle Power Plant. The features of this system are the Estimate of Emergency Level for Operation and the Prediction of Subsequent Abnormality, adding to the Diagnosis of Cause and the Operation Guidance. Moreover in this system, Diagnosis of Cause was improved by using our original method and support screens can be displayed for educational means in normal condition as well. (Authors)

  12. Innovative TRU Burners and Fuel Cycles Options for Phase-Out and Regional Scenarios

    International Nuclear Information System (INIS)

    Vezzoni, B.; Gabrielli, F.; Rineiski, A.; Schwenk-Ferrero, A.; Andriolo, L.; Maschek, W.

    2015-01-01

    Partitioning and transmutation (P and T) technologies may be considered either for minor actinides (MAs) inventory stabilisation (typical for on-going/regional scenarios) or for a drastic reduction of the transuranics inventory (as in phasing-out scenarios). In this paper, two sodium-cooled fast reactor cores, based on the French ASTRID design and characterised by different amounts of MAs in the fuel, are proposed. Attention focuses on the safety and on the burning performances of the systems. The behaviour of the systems under dynamic conditions has been investigated considering phasing-out and on-going fuel cycle scenarios. The results demonstrate the flexibility of such systems when employed in different kinds of fuel cycles. The impact of different parameters, such as the initial isotopic vector (and Cm content) and the cooling time before reprocessing, on the simulation results is investigated as well. (authors)

  13. Self-phase modulation of a single-cycle THz pulse

    DEFF Research Database (Denmark)

    Turchinovich, Dmitry; Hvam, Jørn Märcher; Hoffmann, M. C.

    2013-01-01

    We demonstrate self-phase modulation (SPM) of a single-cycle THz pulse in a semiconductor, using bulk n-GaAs as a model system. The SPM arises from the heating of free electrons in the electric field of the THz pulse. Electron heating leads to an ultrafast reduction of the plasma frequency, which...... results in a strong modification of the THz-range dielectric function of the material. THz SPM is observed directly in the time domain as a characteristic reshaping of single-cycle THz pulse. In the frequency domain, it corresponds to a strong frequency-dependent refractive index nonlinearity of n...

  14. Menstrual cycle phase affects discrimination of infant cuteness.

    Science.gov (United States)

    Lobmaier, Janek S; Probst, Fabian; Perrett, David I; Heinrichs, Markus

    2015-04-01

    Recent studies have shown that women are more sensitive than men to subtle cuteness differences in infant faces. It has been suggested that raised levels in estradiol and progesterone may be responsible for this advantage. We compared young women's sensitivity to computer-manipulated baby faces varying in cuteness. Thirty-six women were tested once during ovulation and once during the luteal phase of their menstrual cycle. In a two alternative forced-choice experiment, participants chose the baby which they thought was cuter (Task 1), younger (Task 2), or the baby that they would prefer to babysit (Task 3). Saliva samples to assess levels of estradiol, progesterone and testosterone were collected at each test session. During ovulation, women were more likely to choose the cuter baby than during the luteal phase, in all three tasks. These results suggest that cuteness discrimination may be driven by cyclic hormonal shifts. However none of the measured hormones were related to increased cuteness sensitivity. We speculate that other hormones than the ones measured here might be responsible for the increased sensitivity to subtle cuteness differences during ovulation. Copyright © 2015 Elsevier Inc. All rights reserved.

  15. Space Launch System Accelerated Booster Development Cycle

    Science.gov (United States)

    Arockiam, Nicole; Whittecar, William; Edwards, Stephen

    2012-01-01

    , affordability is defined as lifecycle cost, which includes design, development, test, and engineering (DDT&E), production and operational costs (P&O). For this study, the system objectives include reducing DDT&E schedule by a factor of three, showing 99.9% reliability, flying up to four times per year, serving both crew and cargo missions, and evolving to a lift capability of 130 metric tons.3 After identifying gaps in the current system s capabilities, this study seeks to identify non-traditional and innovative technologies and processes that may improve performance in these areas and assess their impacts on booster system development. The DDT&E phase may be improved by incorporating incremental development testing and integrated demonstrations to mitigate risk. To further reduce DDT&E, this study will also consider how aspects of the booster system may have commonality with other users, such as the Department of Defense, commercial applications, or international partners; by sharing some of the risk and investment, the overall development cost may be reduced. Consideration is not limited to solid and liquid rocket boosters. A set of functional performance characteristics, such as engine thrust, specific impulse (Isp), mixture ratio, and throttle range are identified and their impacts on the system are evaluated. This study also identifies how such characteristics affect overall life cycle cost, including DDT&E and fixed and variable P&O.

  16. Cascaded recompression closed brayton cycle system

    Energy Technology Data Exchange (ETDEWEB)

    Pasch, James J.

    2018-01-02

    The present disclosure is directed to a cascaded recompression closed Brayton cycle (CRCBC) system and method of operation thereof, where the CRCBC system includes a compressor for compressing the system fluid, a separator for generating fluid feed streams for each of the system's turbines, and separate segments of a heater that heat the fluid feed streams to different feed temperatures for the system's turbines. Fluid exiting each turbine is used to preheat the fluid to the turbine. In an embodiment, the amount of heat extracted is determined by operational costs.

  17. Cascaded recompression closed brayton cycle system

    Science.gov (United States)

    Pasch, James J.

    2018-01-02

    The present disclosure is directed to a cascaded recompression closed Brayton cycle (CRCBC) system and method of operation thereof, where the CRCBC system includes a compressor for compressing the system fluid, a separator for generating fluid feed streams for each of the system's turbines, and separate segments of a heater that heat the fluid feed streams to different feed temperatures for the system's turbines. Fluid exiting each turbine is used to preheat the fluid to the turbine. In an embodiment, the amount of heat extracted is determined by operational costs.

  18. Brayton-Cycle Baseload Power Tower CSP System

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, Bruce [Wilson Solarpower Corporation, Boston, MA (United States)

    2013-12-31

    The primary objectives of Phase 2 of this Project were:1. Engineer, fabricate, and conduct preliminary testing on a low-pressure, air-heating solar receiver capable of powering a microturbine system to produce 300kWe while the sun is shining while simultaneously storing enough energy thermally to power the system for up to 13 hours thereafter. 2. Cycle-test a high-temperature super alloy, Haynes HR214, to determine its efficacy for the system’s high-temperature heat exchanger. 3. Engineer the thermal energy storage system. This Phase 2 followed Wilson’s Phase 1, which primarily was an engineering feasibility study to determine a practical and innovative approach to a full Brayton-cycle system configuration that could meet DOE’s targets. Below is a summary table of the DOE targets with Wilson’s Phase 1 Project results. The results showed that a Brayton system with an innovative (low pressure) solar receiver with ~13 hours of dry (i.e., not phase change materials or molten salts but rather firebrick, stone, or ceramics) has the potential to meet or exceed DOE targets. Such systems would consist of pre-engineered, standardized, factory-produced modules to minimize on-site costs while driving down costs through mass production. System sizes most carefully analyzed were in the range of 300 kWe to 2 MWe. Such systems would also use off-the-shelf towers, blowers, piping, microturbine packages, and heliostats. Per DOE’s instructions, LCOEs are based on the elevation and DNI levels of Daggett, CA, for a 100 MWe power plant following 2 GWe of factory production of the various system components.

  19. Development of FBR cycle data base system (II)

    International Nuclear Information System (INIS)

    Kubota, Sadae; Ohtaki, Akira; Hirao, Kazuhiro

    2003-05-01

    In the 'Feasibility Study on Commercialized FBR Cycle Systems (F/S)', scenario evaluations, cost-benefit evaluations and system characteristic evaluations to show the significance of the FBR cycle system introduction concretely are performed while design studies for FBR plants, reprocessing systems and fabrication systems are conducted. In these evaluations, future society of various conditions and situation is assumed, and investigation and analysis about needs and social effects of FBR cycle are carried out. In this study, promising FBR cycle concepts are suggested by taking information such as domestic and foreign policies and bills, an economic prediction, a supply and demand prediction of resources, a project of technology development into consideration in addition to system design information. The development of the FBR Cycle Database which this report introduced started in 1999 fiscal year to enable managed unitarity and searched reference information to use for the above scenario evaluations, cost-benefit evaluations and system characteristic evaluations. In 2000 fiscal year, its prototype was made and used tentatively, and we extracted the problems in operation and functions from that, and, in 2001 fiscal year, the entry system and the search system using the Web page were made in order to solve problems of the prototype, and started use in our group. Moreover, in 2002 fiscal year, we expanded and improved the search system and promoted the efficiency of management work, and use in JNC through intranet of the database was started. In addition, as a result of having made the entry of about 350 data in 2002 fiscal year, the collected number of the database reaches about 7,250 by the end of March, 2003. We are to continue the entry of related information of various evaluations in F/S phase 2 from now on. In addition, we are to examine improvement of convenience of the search system and cooperation with the economy database. (author)

  20. The Cell Cycle: An Activity Using Paper Plates to Represent Time Spent in Phases of the Cell Cycle

    Science.gov (United States)

    Scherer, Yvette D.

    2014-01-01

    In this activity, students are given the opportunity to combine skills in math and geometry for a biology lesson in the cell cycle. Students utilize the data they collect and analyze from an online onion-root-tip activity to create a paper-plate time clock representing a 24-hour cell cycle. By dividing the paper plate into appropriate phases of…

  1. Implementing Life Cycle Assessment in systems development

    DEFF Research Database (Denmark)

    Bhander, Gurbakhash Singh; Hauschild, Michael Zwicky; McAloone, Timothy Charles

    2003-01-01

    and the rapid changes in markets for many products. The overall aim of the paper is to provide an understanding of the environmental issues involved in the early stages of product development and the capacity of life cycle assessment techniques to address these issues. The paper aims to outline the problems...... for the designer in evaluating the environmental benignity of the product from the outset and to provide the designer with a framework for decision support based on the performance evaluation at different stages of the design process. The overall aim of this paper is to produce an in-depth understanding...... of possibilities which can be introduced in the design stage compared to the other life cycle stages of the product system. The paper collects experiences and ideas around the state-of-the-art in eco-design, from literature and personal experience and further provides eco-design life cycle assessment strategies...

  2. Performance research on modified KCS (Kalina cycle system) 11 without throttle valve

    International Nuclear Information System (INIS)

    He, Jiacheng; Liu, Chao; Xu, Xiaoxiao; Li, Yourong; Wu, Shuangying; Xu, Jinliang

    2014-01-01

    Two modified systems based on a KCS (Kalina cycle system) 11 with a two-phase expander to substitute a throttle valve are proposed. The two-phase expander is located between the regenerator and the absorber in the B-modified cycle and between the separator and the regenerator in the C-modified cycle. A thermodynamic performance analysis of both the original KCS 11 and the modified systems is carried out. The optimization of two key parameters (the concentration of working fluid and the temperature of cooling water) is also conducted. It is shown that the two modified cycles have different performance under the investigated conditions. Results also indicate that the C-modified cycle can obtain better thermodynamic effect than the B-modified cycle. The temperature of cooling water plays an important role in improving the system performance. When the cooling water temperature drops from 303 K to 278 K, the C-modified cycle thermal efficiency can be improved by 27%. - Highlights: • Throttling valve is replaced by a two-phase expander to recover the expansion work. • Thermodynamic performance of two modified cycle systems is very different. • The maximum increase of work output by C-modified cycle compared with KCS (Kalina cycle system) 11 is 9.4%. • The ranges of ammonia content of B-modified cycle are rather larger

  3. Composite Repair System, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — GTL has developed an innovative composite repair methodology known as the Composite Repair System (CRS). In this phase I effort, CRS is being developed for the...

  4. Berry phase in entangled systems

    International Nuclear Information System (INIS)

    Bertlmann, R.A.; Hasegawa, Y.; Hiesmayr, B.C.; Durstberger, C.

    2005-01-01

    Full text: The influence of the geometric phase, in particular the Berry phase, on an entangled spin-1/2 system is studied. We discuss in detail the case, where the geometric phase is generated only by one part of the Hilbert space. We are able to cancel the effects of the dynamical phase by using the 'spin-echo' method. We analyze how the Berry phase affects the Bell angles and the maximal violation of a CHSH-Bell inequality. Furthermore, we suggest an experimental realization of our setup within neutron interferometry. It is possible to create entanglement between different degrees of freedom (spin and spatial degree of freedom) for a single neutron. The influence of the geometrical phase on the entangled neutron state is tested experimentally which is work in progress. (author)

  5. Systems Analyses of Advanced Brayton Cycles

    Energy Technology Data Exchange (ETDEWEB)

    A.D. Rao; D.J. Francuz; J.D. Maclay; J. Brouwer; A. Verma; M. Li; G.S. Samuelsen

    2008-09-30

    The main objective is to identify and assess advanced improvements to the Brayton Cycle (such as but not limited to firing temperature, pressure ratio, combustion techniques, intercooling, fuel or combustion air augmentation, enhanced blade cooling schemes) that will lead to significant performance improvements in coal based power systems. This assessment is conducted in the context of conceptual design studies (systems studies) that advance state-of-art Brayton cycles and result in coal based efficiencies equivalent to 65% + on natural gas basis (LHV), or approximately an 8% reduction in heat rate of an IGCC plant utilizing the H class steam cooled gas turbine. H class gas turbines are commercially offered by General Electric and Mitsubishi for natural gas based combined cycle applications with 60% efficiency (LHV) and it is expected that such machine will be offered for syngas applications within the next 10 years. The studies are being sufficiently detailed so that third parties will be able to validate portions or all of the studies. The designs and system studies are based on plants for near zero emissions (including CO{sub 2}). Also included in this program is the performance evaluation of other advanced technologies such as advanced compression concepts and the fuel cell based combined cycle. The objective of the fuel cell based combined cycle task is to identify the desired performance characteristics and design basis for a gas turbine that will be integrated with an SOFC in Integrated Gasification Fuel Cell (IGFC) applications. The goal is the conceptualization of near zero emission (including CO{sub 2} capture) integrated gasification power plants producing electricity as the principle product. The capability of such plants to coproduce H{sub 2} is qualitatively addressed. Since a total systems solution is critical to establishing a plant configuration worthy of a comprehensive market interest, a baseline IGCC plant scheme is developed and used to study

  6. Entry into the Postparental Phase of the Family Life Cycle

    Directory of Open Access Journals (Sweden)

    Barbara Wawrzyniak

    2015-02-01

    Full Text Available Der Originalbeitrag in deutscher Sprache ist verfügbar unter: Bd. 40 (2015: Ausgewählte deutsche BeiträgeThe article examines entry into the postparental phase of the family life cycle, which is the familial situation when all children have moved out of the parental household. We position this event chronologically within the life course and examine the probability of occurrence. Using panel data (3 survey waves covering a period of 40 years of a cohort of former North-Rhine Westphalian grammar school pupils, event history models (Cox regression are employed to analyse what factors accelerate or decelerate the transition. This revealed that the parent’s individual biography (in particular the age at the own move out, age at the birth of the first child and the number of children has a major impact on the time of occurrence, while the occupational history has no effect. In addition, sons delay the transition, while children’s academic studies and occupation accelerate it.

  7. Phase transition in finite systems

    International Nuclear Information System (INIS)

    Chomaz, Ph.; Duflot, V.; Duflot, V.; Gulminelli, F.

    2000-01-01

    In this paper we present a review of selected aspects of Phase transitions in finite systems applied in particular to the liquid-gas phase transition in nuclei. We show that the problem of the non existence of boundary conditions can be solved by introducing a statistical ensemble with an averaged constrained volume. In such an ensemble the microcanonical heat capacity becomes negative in the transition region. We show that the caloric curve explicitly depends on the considered transformation of the volume with the excitation energy and so does not bear direct informations on the characteristics of the phase transition. Conversely, partial energy fluctuations are demonstrated to be a direct measure of the equation of state. Since the heat capacity has a negative branch in the phase transition region, the presence of abnormally large kinetic energy fluctuations is a signal of the liquid gas phase transition. (author)

  8. Life cycle management of service water systems

    International Nuclear Information System (INIS)

    Egan, Geoffrey R.; Besuner, Philip M.; Mahajan, Sat P.

    2004-01-01

    As nuclear plants age, more attention must focus on age and time dependent degradation mechanisms such as corrosion, erosion, fatigue, etc. These degradation mechanisms can best be managed by developing a life cycle management plan which integrates past historical data, current conditions and future performance needs. In this paper we present two examples of life cycle management. In the first example, the 20-year maintenance history of a sea water cooling system (cement-lined, cast iron) is reviewed to develop attributes like maintenance cost, spare part inventory, corrosion, and repair data. Based on this information, the future expected damage rate was forecast. The cost of managing the future damage was compared with the cost to replace (in kind and with upgraded materials. A decision optimization scheme was developed to choose the least cost option from: a) Run as-is and repair; b) replace in kind; or c) replace with upgraded material and better design. In the second example, life cycle management techniques were developed for a ceilcote lined steel pipe cooling water system. Screens (fixed and traveling), filters, pumps, motors, valves, and piping were evaluated. (author)

  9. Effects of menstrual cycle phase on cocaine self-administration in rhesus macaques.

    Science.gov (United States)

    Cooper, Ziva D; Foltin, Richard W; Evans, Suzette M

    2013-01-01

    Epidemiological findings suggest that men and women vary in their pattern of cocaine use resulting in differences in cocaine dependence and relapse rates. Preclinical laboratory studies have demonstrated that female rodents are indeed more sensitive to cocaine's reinforcing effects than males, with estrous cycle stage as a key determinant of this effect. The current study sought to extend these findings to normally cycling female rhesus macaques, a species that shares a nearly identical menstrual cycle to humans. Dose-dependent intravenous cocaine self-administration (0.0125, 0.0250, and 0.0500 mg/kg/infusion) using a progressive-ratio schedule of reinforcement was determined across the menstrual cycle. The menstrual cycle was divided into 5 discrete phases - menses, follicular, periovulatory, luteal, and late luteal phases - verified by the onset of menses and plasma levels of estradiol and progesterone. Dependent variables including number of infusions self-administered per session, progressive ratio breakpoint, and cocaine intake were analyzed according to cocaine dose and menstrual cycle phase. Analysis of plasma hormone levels verified phase-dependent fluctuations of estradiol and progesterone, with estrogen levels peaking during the periovulatory phase, and progesterone peaking during the luteal phase. Progressive ratio breakpoint, infusions self-administered, and cocaine intake did not consistently vary based on menstrual cycle phase. These findings demonstrate that under the current experimental parameters, the reinforcing effects of cocaine did not vary across the menstrual cycle in a systematic fashion in normally cycling rhesus macaques. Copyright © 2012 Elsevier Inc. All rights reserved.

  10. A signature-based method for indexing cell cycle phase distribution from microarray profiles

    Directory of Open Access Journals (Sweden)

    Mizuno Hideaki

    2009-03-01

    Full Text Available Abstract Background The cell cycle machinery interprets oncogenic signals and reflects the biology of cancers. To date, various methods for cell cycle phase estimation such as mitotic index, S phase fraction, and immunohistochemistry have provided valuable information on cancers (e.g. proliferation rate. However, those methods rely on one or few measurements and the scope of the information is limited. There is a need for more systematic cell cycle analysis methods. Results We developed a signature-based method for indexing cell cycle phase distribution from microarray profiles under consideration of cycling and non-cycling cells. A cell cycle signature masterset, composed of genes which express preferentially in cycling cells and in a cell cycle-regulated manner, was created to index the proportion of cycling cells in the sample. Cell cycle signature subsets, composed of genes whose expressions peak at specific stages of the cell cycle, were also created to index the proportion of cells in the corresponding stages. The method was validated using cell cycle datasets and quiescence-induced cell datasets. Analyses of a mouse tumor model dataset and human breast cancer datasets revealed variations in the proportion of cycling cells. When the influence of non-cycling cells was taken into account, "buried" cell cycle phase distributions were depicted that were oncogenic-event specific in the mouse tumor model dataset and were associated with patients' prognosis in the human breast cancer datasets. Conclusion The signature-based cell cycle analysis method presented in this report, would potentially be of value for cancer characterization and diagnostics.

  11. Nuclear fuel cycle simulation system (VISTA)

    International Nuclear Information System (INIS)

    2007-02-01

    The Nuclear Fuel Cycle Simulation System (VISTA) is a simulation system which estimates long term nuclear fuel cycle material and service requirements as well as the material arising from the operation of nuclear fuel cycle facilities and nuclear power reactors. The VISTA model needs isotopic composition of spent nuclear fuel in order to make estimations of the material arisings from the nuclear reactor operation. For this purpose, in accordance with the requirements of the VISTA code, a new module called Calculating Actinide Inventory (CAIN) was developed. CAIN is a simple fuel depletion model which requires a small number of input parameters and gives results in a very short time. VISTA has been used internally by the IAEA for the estimation of: spent fuel discharge from the reactors worldwide, Pu accumulation in the discharged spent fuel, minor actinides (MA) accumulation in the spent fuel, and in the high level waste (HLW) since its development. The IAEA decided to disseminate the VISTA tool to Member States using internet capabilities in 2003. The improvement and expansion of the simulation code and the development of the internet version was started in 2004. A website was developed to introduce the simulation system to the visitors providing a simple nuclear material flow calculation tool. This website has been made available to Member States in 2005. The development work for the full internet version is expected to be fully available to the interested parties from IAEA Member States in 2007 on its website. This publication is the accompanying text which gives details of the modelling and an example scenario

  12. Multitube coaxial closed cycle gas laser system

    International Nuclear Information System (INIS)

    Davis, J.W.; Walch, A.P.

    1975-01-01

    A gas laser design capable of long term reliable operation in a commercial environment is disclosed. Various construction details which insulate the laser optics from mechanical distortions and vibrations inevitably present in the environment are developed. Also, a versatile optical cavity made up of modular units which render the basic laser configuration adaptable to alternate designs with different output capabilities is shown in detail. The system built around a convection laser operated in a closed cycle and the working medium is a gas which is excited by direct current electric discharges. (auth)

  13. Rankine cycle waste heat recovery system

    Science.gov (United States)

    Ernst, Timothy C.; Nelson, Christopher R.

    2015-09-22

    A waste heat recovery (WHR) system connects a working fluid to fluid passages formed in an engine block and/or a cylinder head of an internal combustion engine, forming an engine heat exchanger. The fluid passages are formed near high temperature areas of the engine, subjecting the working fluid to sufficient heat energy to vaporize the working fluid while the working fluid advantageously cools the engine block and/or cylinder head, improving fuel efficiency. The location of the engine heat exchanger downstream from an EGR boiler and upstream from an exhaust heat exchanger provides an optimal position of the engine heat exchanger with respect to the thermodynamic cycle of the WHR system, giving priority to cooling of EGR gas. The configuration of valves in the WHR system provides the ability to select a plurality of parallel flow paths for optimal operation.

  14. Phase transitions in finite systems

    Energy Technology Data Exchange (ETDEWEB)

    Chomaz, Ph. [Grand Accelerateur National d' Ions Lourds (GANIL), DSM-CEA / IN2P3-CNRS, 14 - Caen (France); Gulminelli, F. [Caen Univ., 14 (France). Lab. de Physique Corpusculaire

    2002-07-01

    In this series of lectures we will first review the general theory of phase transition in the framework of information theory and briefly address some of the well known mean field solutions of three dimensional problems. The theory of phase transitions in finite systems will then be discussed, with a special emphasis to the conceptual problems linked to a thermodynamical description for small, short-lived, open systems as metal clusters and data samples coming from nuclear collisions. The concept of negative heat capacity developed in the early seventies in the context of self-gravitating systems will be reinterpreted in the general framework of convexity anomalies of thermo-statistical potentials. The connection with the distribution of the order parameter will lead us to a definition of first order phase transitions in finite systems based on topology anomalies of the event distribution in the space of observations. Finally a careful study of the thermodynamical limit will provide a bridge with the standard theory of phase transitions and show that in a wide class of physical situations the different statistical ensembles are irreducibly inequivalent. (authors)

  15. Phase transitions in finite systems

    International Nuclear Information System (INIS)

    Chomaz, Ph.; Gulminelli, F.

    2002-01-01

    In this series of lectures we will first review the general theory of phase transition in the framework of information theory and briefly address some of the well known mean field solutions of three dimensional problems. The theory of phase transitions in finite systems will then be discussed, with a special emphasis to the conceptual problems linked to a thermodynamical description for small, short-lived, open systems as metal clusters and data samples coming from nuclear collisions. The concept of negative heat capacity developed in the early seventies in the context of self-gravitating systems will be reinterpreted in the general framework of convexity anomalies of thermo-statistical potentials. The connection with the distribution of the order parameter will lead us to a definition of first order phase transitions in finite systems based on topology anomalies of the event distribution in the space of observations. Finally a careful study of the thermodynamical limit will provide a bridge with the standard theory of phase transitions and show that in a wide class of physical situations the different statistical ensembles are irreducibly inequivalent. (authors)

  16. Does the phase of menstrual cycle affect MR-guided focused ultrasound surgery of uterine leiomyomas?

    International Nuclear Information System (INIS)

    So, Minna J.; Fennessy, Fiona M.; Zou, Kelly H.; McDannold, Nathan; Hynynen, Kullervo; Jolesz, Ferenc A.; Stewart, Elizabeth A.; Rybicki, Frank J.; Tempany, Clare M.

    2006-01-01

    Purpose: To determine whether the phase of menstrual cycle at the time of MR-guided focused ultrasound surgery (MRgFUS) treatment for uterine leiomyomas affects treatment outcome. Methods: We enrolled all patients participating in a prospective phase III clinical trial from our center who completed 6 months of clinical and imaging follow-up. Patients with irregular cycles and those on oral contraceptives were excluded. Data prospectively documenting the date of the last menstrual period (LMP) at the time of treatment, length and duration of cycle, and raw symptom severity score (SSS) from the Uterine Fibroid Symptom and Quality of Life questionnaire, at baseline and 6 months were collected. Proliferative phase patients were determined retrospectively as those who were treated within less than 14 days from LMP; secretory phase patients were classified as those who were treated greater than 14 days from LMP. Results: A total of 58 patients were enrolled. There was no significant difference in the mean SSS at baseline and mean SSS at 6 months between patients treated in the proliferative versus secretory phase of the cycle. No significant difference in the SSS change from baseline to 6 months was seen between the two groups. Conclusions: Menstrual cycle phase does not influence MRgFUS treatment outcome. Symptomatic improvement occurs with treatment during either phase of the menstrual cycle. Thus, the scheduling of MRgFUS treatment need not be based upon the phase of the menstrual cycle

  17. Does the phase of menstrual cycle affect MR-guided focused ultrasound surgery of uterine leiomyomas?

    Energy Technology Data Exchange (ETDEWEB)

    So, Minna J. [Department of Radiology, Brigham and Women' s Hospital/Harvard Medical School, Boston, MA (United States); Fennessy, Fiona M. [Department of Radiology, Brigham and Women' s Hospital/Harvard Medical School, Boston, MA (United States); Zou, Kelly H. [Department of Radiology, Brigham and Women' s Hospital/Harvard Medical School, Boston, MA (United States); McDannold, Nathan [Department of Radiology, Brigham and Women' s Hospital/Harvard Medical School, Boston, MA (United States); Hynynen, Kullervo [Department of Radiology, Brigham and Women' s Hospital/Harvard Medical School, Boston, MA (United States); Jolesz, Ferenc A. [Department of Radiology, Brigham and Women' s Hospital/Harvard Medical School, Boston, MA (United States); Stewart, Elizabeth A. [Department of Obstetrics and Gynecology, Brigham and Women' s Hospital/Harvard Medical School, Boston, MA (United States); Rybicki, Frank J. [Department of Radiology, Brigham and Women' s Hospital/Harvard Medical School, Boston, MA (United States); Tempany, Clare M. [Department of Radiology, Brigham and Women' s Hospital/Harvard Medical School, Boston, MA (United States)]. E-mail: ctempanyafdhal@partners.org

    2006-08-15

    Purpose: To determine whether the phase of menstrual cycle at the time of MR-guided focused ultrasound surgery (MRgFUS) treatment for uterine leiomyomas affects treatment outcome. Methods: We enrolled all patients participating in a prospective phase III clinical trial from our center who completed 6 months of clinical and imaging follow-up. Patients with irregular cycles and those on oral contraceptives were excluded. Data prospectively documenting the date of the last menstrual period (LMP) at the time of treatment, length and duration of cycle, and raw symptom severity score (SSS) from the Uterine Fibroid Symptom and Quality of Life questionnaire, at baseline and 6 months were collected. Proliferative phase patients were determined retrospectively as those who were treated within less than 14 days from LMP; secretory phase patients were classified as those who were treated greater than 14 days from LMP. Results: A total of 58 patients were enrolled. There was no significant difference in the mean SSS at baseline and mean SSS at 6 months between patients treated in the proliferative versus secretory phase of the cycle. No significant difference in the SSS change from baseline to 6 months was seen between the two groups. Conclusions: Menstrual cycle phase does not influence MRgFUS treatment outcome. Symptomatic improvement occurs with treatment during either phase of the menstrual cycle. Thus, the scheduling of MRgFUS treatment need not be based upon the phase of the menstrual cycle.

  18. A Cold Cycle Dilution Refrigerator for Space Applications, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — The cold cycle dilution refrigerator is a continuous refrigerator capable of cooling to temperatures below 100 mK that makes use of a novel thermal magnetic pump....

  19. A model for a knowledge-based system's life cycle

    Science.gov (United States)

    Kiss, Peter A.

    1990-01-01

    The American Institute of Aeronautics and Astronautics has initiated a Committee on Standards for Artificial Intelligence. Presented here are the initial efforts of one of the working groups of that committee. The purpose here is to present a candidate model for the development life cycle of Knowledge Based Systems (KBS). The intent is for the model to be used by the Aerospace Community and eventually be evolved into a standard. The model is rooted in the evolutionary model, borrows from the spiral model, and is embedded in the standard Waterfall model for software development. Its intent is to satisfy the development of both stand-alone and embedded KBSs. The phases of the life cycle are detailed as are and the review points that constitute the key milestones throughout the development process. The applicability and strengths of the model are discussed along with areas needing further development and refinement by the aerospace community.

  20. Effect of door opening and defrost cycle on a freezer with phase change panels

    International Nuclear Information System (INIS)

    Gin, B.; Farid, M.M.; Bansal, P.K.

    2010-01-01

    An investigation into the effectiveness of phase change material (PCM) panels placed against the internal walls of a freezer to maintain stable temperatures in the presence of heat loads such as door openings, defrosting, and loss of electrical power was carried out. Temperature response was studied during loss of power, a defrost cycle lasting 30 min, and a door opening scheme of 13 door openings over an 11 h period. This PCM system has significantly decreased the rate of temperature increase inside the freezer during defrosting and power loss. Energy consumption was measured during steady operation, a defrost cycle of 30 min, and a scheme of eight door openings at 40 min intervals. It was found that heat loads caused greater energy consumption, and that the presence of PCM during defrosting and door openings resulted in slightly lower energy consumption compared to without PCM.

  1. Life Cycle Assessment of Wall Systems

    Science.gov (United States)

    Ramachandran, Sriranjani

    Natural resource depletion and environmental degradation are the stark realities of the times we live in. As awareness about these issues increases globally, industries and businesses are becoming interested in understanding and minimizing the ecological footprints of their activities. Evaluating the environmental impacts of products and processes has become a key issue, and the first step towards addressing and eventually curbing climate change. Additionally, companies are finding it beneficial and are interested in going beyond compliance using pollution prevention strategies and environmental management systems to improve their environmental performance. Life-cycle Assessment (LCA) is an evaluative method to assess the environmental impacts associated with a products' life-cycle from cradle-to-grave (i.e. from raw material extraction through to material processing, manufacturing, distribution, use, repair and maintenance, and finally, disposal or recycling). This study focuses on evaluating building envelopes on the basis of their life-cycle analysis. In order to facilitate this analysis, a small-scale office building, the University Services Building (USB), with a built-up area of 148,101 ft2 situated on ASU campus in Tempe, Arizona was studied. The building's exterior envelope is the highlight of this study. The current exterior envelope is made of tilt-up concrete construction, a type of construction in which the concrete elements are constructed horizontally and tilted up, after they are cured, using cranes and are braced until other structural elements are secured. This building envelope is compared to five other building envelope systems (i.e. concrete block, insulated concrete form, cast-in-place concrete, steel studs and curtain wall constructions) evaluating them on the basis of least environmental impact. The research methodology involved developing energy models, simulating them and generating changes in energy consumption due to the above mentioned

  2. Effects of the menstrual cycle phases on the tilt testing results in vasovagal patients.

    Science.gov (United States)

    Zyśko, Dorota; Gajek, Jacek; Terpiłowski, Lukasz; Agrawal, Anil Kumar; Wróblewski, Paweł; Rudnicki, Jerzy

    2012-08-01

    The aim of the study was to assess the distribution of positive tilt testing (TT) throughout the menstrual cycle and to determine if the phase of menstrual cycle contributes to the duration of the loss of consciousness. TT results of 183 premenopausal women, aged 29.5 ± 9.8 years, were studied. The menstrual cycle was divided into four phases based on the first day of the last menstrual bleeding: perimenstrual (M), preovulatory (F), periovulatory (O) and postovulatory (L). Positive TT results were equally distributed. In patients with TT in O phase, the highest percentage of NTG provocation was needed. Patients in L phase had significantly lower incidence of cardioinhibitory reaction. The longest duration of loss of consciousness was in the M phase. Multiple regression analysis revealed that the duration of loss of consciousness during positive TT was significantly associated with higher number of syncopal events, TT performed in M phase and lower heart rate at TT termination. Cardiodepressive type of neurocardiogenic reaction was more frequent during M and O phase than during L phase. The distribution of positive TT results as well as syncope and presyncope does not differ throughout the menstrual cycle. Diagnostic TT in premenopausal women with unexplained syncope could be performed irrespective of the phase of menstrual cycle. TT has similar sensitivity throughout the menstrual cycle. During the postovulatory phase, cardioinhibitory reaction is less frequent than in M and O phases. The duration of loss of consciousness is longer during the M phase of the menstrual cycle independently of the higher syncope number and lower heart rate at TT termination.

  3. Self-phase modulation of a single-cycle terahertz pulse by nonlinear free-carrier response in a semiconductor

    DEFF Research Database (Denmark)

    Turchinovich, Dmitry; Hvam, Jørn Märcher; Hoffmann, Matthias C.

    2012-01-01

    We investigate the self-phase modulation (SPM) of a single-cycle terahertz pulse in a semiconductor, using bulk n-GaAs as a model system. The SPM arises from the heating of free electrons in the electric field of the terahertz pulse, leading to an ultrafast reduction of the plasma frequency...

  4. Three-phase Photovoltaic Systems

    DEFF Research Database (Denmark)

    Kerekes, Tamas; Sera, Dezso; Máthé, Lászlo

    2015-01-01

    , detailing the different photovoltaic inverter structures and topologies as well as discussing the different control layers within a grid-connected photovoltaic plant. Modulation schemes for various photovoltaic inverter topologies, grid synchronization, current control, active and reactive power control......Photovoltaic technology has experienced unprecedented growth in the last two decades, transforming from mainly off-grid niche generation to a major renewable energy technology, reaching approximately 180 GW of capacity worldwide at the end of 2014. Large photovoltaic power plants interfacing...... the grid through a three-phase power electronic converter are now well on the way to becoming a major player in the power system in many countries. Therefore, this article gives an overview of photovoltaic systems with a focus on three-phase applications, presenting these both from a hardware point of view...

  5. Nuclear Fuel Cycle Information System. A directory of nuclear fuel cycle facilities. 2009 ed

    International Nuclear Information System (INIS)

    2009-04-01

    The Nuclear Fuel Cycle Information System (NFCIS) is an international directory of civilian nuclear fuel cycle facilities, published online as part of the Integrated Nuclear Fuel Cycle Information System (iNFCIS: http://www-nfcis.iaea.org/). This is the fourth hardcopy publication in almost 30 years and it represents a snapshot of the NFCIS database as of the end of 2008. Together with the attached CD-ROM, it provides information on 650 civilian nuclear fuel cycle facilities in 53 countries, thus helping to improve the transparency of global nuclear fuel cycle activities

  6. Effect of operational cycle time length on nitrogen removal in an alternating oxidation ditch system.

    Science.gov (United States)

    Mantziaras, I D; Stamou, A; Katsiri, A

    2011-06-01

    This paper refers to nitrogen removal optimization of an alternating oxidation ditch system through the use of a mathematical model and pilot testing. The pilot system where measurements have been made has a total volume of 120 m(3) and consists of two ditches operating in four phases during one cycle and performs carbon oxidation, nitrification, denitrification and settling. The mathematical model consists of one-dimensional mass balance (convection-dispersion) equations based on the IAWPRC ASM 1 model. After the calibration and verification of the model, simulation system performance was made. Optimization is achieved by testing operational cycles and phases with different time lengths. The limits of EU directive 91/271 for nitrogen removal have been used for comparison. The findings show that operational cycles with smaller time lengths can achieve higher nitrogen removals and that an "equilibrium" between phase time percentages in the whole cycle, for a given inflow, must be achieved.

  7. Method for Controlling Space Transportation System Life Cycle Costs

    Science.gov (United States)

    McCleskey, Carey M.; Bartine, David E.

    2006-01-01

    A structured, disciplined methodology is required to control major cost-influencing metrics of space transportation systems during design and continuing through the test and operations phases. This paper proposes controlling key space system design metrics that specifically influence life cycle costs. These are inclusive of flight and ground operations, test, and manufacturing and infrastructure. The proposed technique builds on today's configuration and mass properties control techniques and takes on all the characteristics of a classical control system. While the paper does not lay out a complete math model, key elements of the proposed methodology are explored and explained with both historical and contemporary examples. Finally, the paper encourages modular design approaches and technology investments compatible with the proposed method.

  8. Study on closed cycle MHD generation systems; Closed cycle MHD hatsuden system no kento

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1988-03-01

    The closed cycle noble gas MHD generation systems are surveyed and studied. The concept of closed cycle noble gas MHD generation is confirmed to extract high enthalpy, and now going into the engineering demonstration stage from the basic research stage. These systems have various characteristics. The highest working temperature is around 1,700 degrees C, which is close to that associated with the existing techniques. Use of helium or argon gas as the working fluid makes the system relatively free of various problems, e.g., corrosion. It can attain a much higher efficiency than the combined cycle involving gas turbine. It suffers less heat loss in the passages, is suitable for small- to medium-capacity power generation systems, and copes with varying load. The compact power generation passages decrease required size of the superconducting magnet. The technical problems to be solved include optimization of power generation conditions, demonstration of durability of the power generation passages, injection/recovery of the seed material, treatment of the working gas to remove molecular impurities, and development of heat exchangers serviceable at high temperature produced by direct combustion of coal. The conceptual designs of the triple combined system are completed. (NEDO)

  9. The status of nuclear fuel cycle system analysis for the development of advanced nuclear fuel cycles

    Energy Technology Data Exchange (ETDEWEB)

    Ko, Won Il; Kim, Seong Ki; Lee, Hyo Jik; Chang, Hong Rae; Kwon, Eun Ha; Lee, Yoon Hee; Gao, Fanxing [KAERI, Daejeon (Korea, Republic of)

    2011-11-15

    The system analysis has been used with different system and objectives in various fields. In the nuclear field, the system can be applied from uranium mining to spent fuel reprocessing or disposal which is called the nuclear fuel cycle. The analysis of nuclear fuel cycle can be guideline for development of advanced fuel cycle through integrating and evaluating the technologies. For this purpose, objective approach is essential and modeling and simulation can be useful. In this report, several methods which can be applicable for development of advanced nuclear fuel cycle, such as TRL, simulation and trade analysis were explained with case study

  10. Phase lock of rapid cycling synchrotron and neutron choppers

    International Nuclear Information System (INIS)

    Praeg, W.; McGhee, D.; Volk, G.

    1981-01-01

    The 500-MeV synchrotron of Argonne's Intense Pulsed Neutron Source operates at 30 Hz. Its beam spill must be locked to neutron choppers with a precision of +- 0.5 μs. A chopper and an accelerator have large and different inertias. This makes synchronization by phase lock to the 60-Hz power line extremely difficult. We solved the phasing problems by running both the Ring Magnet Power Supply (RMPS) of the synchrotron and the chopper motors from a common oscillator that is stable to 1 ppM and by controlling five quantities of the RMPS. The quantities controlled by feedback loops are dc current, injection current, ejection current, resonant frequency, and the phase shift between the synchrotron peak field and the chopper window

  11. Resting state alpha frequency is associated with menstrual cycle phase, estradiol and use of oral contraceptives

    OpenAIRE

    Brötzner, Christina P.; Klimesch, Wolfgang; Doppelmayr, Michael; Zauner, Andrea; Kerschbaum, Hubert H.

    2014-01-01

    Ongoing intrinsic brain activity in resting, but awake humans is dominated by alpha oscillations. In human, individual alpha frequency (IAF) is associated with cognitive performance. Noticeable, performance in cognitive and emotional tasks in women is associated with menstrual cycle phase and sex hormone levels, respectively. In the present study, we correlated frequency of alpha oscillation in resting women with menstrual cycle phase, sex hormone level, or use of oral contraceptives. Electro...

  12. Effect of menstrual cycle phase on corticolimbic brain activation by visual food cues.

    Science.gov (United States)

    Frank, Tamar C; Kim, Ginah L; Krzemien, Alicja; Van Vugt, Dean A

    2010-12-02

    Food intake is decreased during the late follicular phase and increased in the luteal phase of the menstrual cycle. While a changing ovarian steroid milieu is believed to be responsible for this behavior, the specific mechanisms involved are poorly understood. Brain activity in response to visual food stimuli was compared during the estrogen dominant peri-ovulatory phase and the progesterone dominant luteal phase of the menstrual cycle. Twelve women underwent functional magnetic resonance imaging during the peri-ovulatory and luteal phases of the menstrual cycle in a counterbalanced fashion. Whole brain T2* images were collected while subjects viewed pictures of high calorie (HC) foods, low calorie (LC) foods, and control (C) pictures presented in a block design. Blood oxygen level dependent (BOLD) signal in the late follicular phase and luteal phase was determined for the contrasts HC-C, LC-C, HC-LC, and LC-HC. Both HC and LC stimuli activated numerous corticolimbic brain regions in the follicular phase, whereas only HC stimuli were effective in the luteal phase. Activation of the nucleus accumbens (NAc), amygdala, and hippocampus in response to the HC-C contrast and the hippocampus in response to the LC-C contrast was significantly increased in the late follicular phase compared to the luteal phase. Activation of the orbitofrontal cortex and mid cingulum in response to the HC-LC contrast was greater during the luteal phase. These results demonstrate for the first time that brain responses to visual food cues are influenced by menstrual cycle phase. We postulate that ovarian steroid modulation of the corticolimbic brain contributes to changes in ingestive behavior during the menstrual cycle. Copyright © 2010 Elsevier B.V. All rights reserved.

  13. Characterizing cycle-to-cycle variations of the shedding cycle in the turbulent wake of a normal flat plate using generalized phase averages

    Science.gov (United States)

    Martinuzzi, Robert

    2016-11-01

    Quasi-periodic vortex shedding in the turbulent wake of a thin-flat plate placed normal to a uniform stream at Reynolds number of 6700 is investigated based on Particle Image Velocimetry experiments. The wake structure and vortex formation are characterized using a generalized phase average (GPA), a refinement of the triple decomposition of Reynolds and Hussain (1970) incorporating elements of mean-field theory (Stuart, 1958). The resulting analysis highlights the importance of cycle-to-cycle variations in characterizing vortex formation, wake topology and the residual turbulent Reynolds Stresses. For example, it is shown that during high-amplitude cycles vorticity is strongly concentrated within the well-organized shed vortices, whereas during low-amplitude cycles the shed vortices are highly distorted resulting in significant modulation of the shedding frequency. It is found that high-amplitude cycles contribute more to the coherent Reynolds stress field while the low-amplitude cycles contribute to the residual stress field. It is further shown that traditional phase-averaging techniques lead to an over-estimation of the residual stress field. Natural Sciences and Engineering Research Council of Canada.

  14. CORONAL DYNAMIC ACTIVITIES IN THE DECLINING PHASE OF A SOLAR CYCLE

    Energy Technology Data Exchange (ETDEWEB)

    Jang, Minhwan; Choe, G. S. [Department of Astronomy and Space Science, Kyung Hee University, Yongin 17104 (Korea, Republic of); Woods, T. N. [Laboratory for Atmospheric and Space Physics, University of Colorado, Boulder, CO 80303 (United States); Hong, Sunhak, E-mail: gchoe@khu.ac.kr [School of Space Research, Kyung Hee University, Yongin 17104 (Korea, Republic of)

    2016-12-10

    It has been known that some solar activity indicators show a double-peak feature in their evolution through a solar cycle, which is not conspicuous in sunspot number. In this Letter, we investigate the high solar dynamic activity in the declining phase of the sunspot cycle by examining the evolution of polar and low-latitude coronal hole (CH) areas, splitting and merging events of CHs, and coronal mass ejections (CMEs) detected by SOHO /LASCO C3 in solar cycle 23. Although the total CH area is at its maximum near the sunspot minimum, in which polar CHs prevail, it shows a comparable second maximum in the declining phase of the cycle, in which low-latitude CHs are dominant. The events of CH splitting or merging, which are attributed to surface motions of magnetic fluxes, are also mostly populated in the declining phase of the cycle. The far-reaching C3 CMEs are also overpopulated in the declining phase of the cycle. From these results we suggest that solar dynamic activities due to the horizontal surface motions of magnetic fluxes extend far in the declining phase of the sunspot cycle.

  15. CORONAL DYNAMIC ACTIVITIES IN THE DECLINING PHASE OF A SOLAR CYCLE

    International Nuclear Information System (INIS)

    Jang, Minhwan; Choe, G. S.; Woods, T. N.; Hong, Sunhak

    2016-01-01

    It has been known that some solar activity indicators show a double-peak feature in their evolution through a solar cycle, which is not conspicuous in sunspot number. In this Letter, we investigate the high solar dynamic activity in the declining phase of the sunspot cycle by examining the evolution of polar and low-latitude coronal hole (CH) areas, splitting and merging events of CHs, and coronal mass ejections (CMEs) detected by SOHO /LASCO C3 in solar cycle 23. Although the total CH area is at its maximum near the sunspot minimum, in which polar CHs prevail, it shows a comparable second maximum in the declining phase of the cycle, in which low-latitude CHs are dominant. The events of CH splitting or merging, which are attributed to surface motions of magnetic fluxes, are also mostly populated in the declining phase of the cycle. The far-reaching C3 CMEs are also overpopulated in the declining phase of the cycle. From these results we suggest that solar dynamic activities due to the horizontal surface motions of magnetic fluxes extend far in the declining phase of the sunspot cycle.

  16. A comparison of production system life cycle models

    Science.gov (United States)

    Attri, Rajesh; Grover, Sandeep

    2012-09-01

    Companies today need to keep up with the rapidly changing market conditions to stay competitive. The main issues in this paper are related to a company's market and its competitors. The prediction of market behavior is helpful for a manufacturing enterprise to build efficient production systems. However, these predictions are usually not reliable. A production system is required to adapt to changing markets, but such requirement entails higher cost. Hence, analyzing different life cycle models of the production system is necessary. In this paper, different life cycle models of the production system are compared to evaluate the distinctive features and the limitations of each model. Furthermore, the difference between product life cycle and production life cycle is summarized, and the effect of product life cycle on production life cycle is explained. Finally, a production system life cycle model, along with key activities to be performed in each stage, is proposed specifically for the manufacturing sector.

  17. Algebraic limit cycles in polynomial systems of differential equations

    International Nuclear Information System (INIS)

    Llibre, Jaume; Zhao Yulin

    2007-01-01

    Using elementary tools we construct cubic polynomial systems of differential equations with algebraic limit cycles of degrees 4, 5 and 6. We also construct a cubic polynomial system of differential equations having an algebraic homoclinic loop of degree 3. Moreover, we show that there are polynomial systems of differential equations of arbitrary degree that have algebraic limit cycles of degree 3, as well as give an example of a cubic polynomial system of differential equations with two algebraic limit cycles of degree 4

  18. Exploring the data constrained phase space of the last Antarctic glacial cycle

    Science.gov (United States)

    Lecavalier, Benoit; Tarasov, Lev

    2017-04-01

    The evolution of the Antarctic Ice Sheet over the last two glacial cycles is studied using the Glacial Systems Model (GSM). Glaciological modelling is an effective tool to generate continental-scale reconstructions over glacial cycles, but the models depend on parameterizations to account for the deficiencies (e.g., missing physics, unresolved sub-grid processes, uncertain boundary conditions) inherent in any numerical model. These parameters, considered together, form a parameter phase space from which sets of parameters can be sampled; each set corresponds to an ice sheet reconstruction. The GSM has been updated with a number of recent developments: hybrid SIA-SSA physics, Schoof grounding line parameterization, broadened degrees of freedom in the climate forcing, sub-shelf melt explicitly dependent on ocean temperatures, improved hydrofracturing, cliff failure at the margins, basal topographic uncertainties, impact of basal drag roughness and subgrid statistics, and first order geoidal corrections in the coupled glacial isostatic adjustment component. Parametric uncertainties are defined in the GSM using >36 ensemble parameters. Prior to conducting a full Bayesian calibration, one must first validate the ability of the GSM to simulate a broad range of responses. We attempt this by latin hypercube sampling of the parameter phase space and comparing the model predictions against our constraint database consisting of past elevation, extent and relative sea level observations and the present day geometry. We document the capability of the GSM to envelope the observational constraints given the parametric uncertainties and discuss the implications for the evolution of the Antarctic Ice Sheet.

  19. Cycle layout studies of S-CO2 cycle for the next generation nuclear system application

    International Nuclear Information System (INIS)

    Ahn, Yoonhan; Bae, Seong Jun; Kim, Minseok; Cho, Seong Kuk; Baik, Seungjoon; Lee, Jeong Ik; Cha, Jae Eun

    2014-01-01

    According to the second law of thermodynamics, the next generation nuclear reactor system efficiency can potentially be increased with higher operating temperature. Fig.1 shows several power conversion system efficiencies and heat sources with respect to the system top operating temperature. As shown in Fig.1, the steam Rankine and gas Brayton cycles have been considered as the major power conversion systems more than several decades. In the next generation reactor operating temperature region (450 - 900 .deg. C), the steam Rankine and gas Brayton cycles have limits due to material problems and low efficiency, respectively. Among the future power conversion systems, S-CO 2 cycle is receiving interests due to several benefits including high efficiency under the mild turbine inlet temperature range (450-650 .deg. C), compact turbomachinery and simple layout compared to the steam Rankine cycle. S-CO 2 cycle can show relatively high efficiency under the mild turbine inlet temperature range (450-600 .deg. C) compared to other power conversion systems. The recompression cycle shows the best efficiency among other layouts and it is suitable for the application to advanced nuclear reactor systems. As S-CO 2 cycle performance can vary depending on the layout configuration, further studies on the layouts are required to design a better performing cycle

  20. Solar origins of solar wind properties during the cycle 23 solar minimum and rising phase of cycle 24

    Science.gov (United States)

    Luhmann, Janet G.; Petrie, Gordon; Riley, Pete

    2012-01-01

    The solar wind was originally envisioned using a simple dipolar corona/polar coronal hole sources picture, but modern observations and models, together with the recent unusual solar cycle minimum, have demonstrated the limitations of this picture. The solar surface fields in both polar and low-to-mid-latitude active region zones routinely produce coronal magnetic fields and related solar wind sources much more complex than a dipole. This makes low-to-mid latitude coronal holes and their associated streamer boundaries major contributors to what is observed in the ecliptic and affects the Earth. In this paper we use magnetogram-based coronal field models to describe the conditions that prevailed in the corona from the decline of cycle 23 into the rising phase of cycle 24. The results emphasize the need for adopting new views of what is ‘typical’ solar wind, even when the Sun is relatively inactive. PMID:25685422

  1. The reversal phase of the bone-remodeling cycle

    DEFF Research Database (Denmark)

    Delaisse, Jean-Marie

    2014-01-01

    coincides with decreased osteoblast recruitment and impaired initiation of bone formation, that is, uncoupling. Overall, this review stresses that coupling does not only depend on molecules able to activate osteogenesis, but that it also demands the presence of osteoprogenitors and ordered cell......The reversal phase couples bone resorption to bone formation by generating an osteogenic environment at remodeling sites. The coupling mechanism remains poorly understood, despite the identification of a number of 'coupling' osteogenic molecules. A possible reason is the poor attention...

  2. Block colourings of 6-cycle systems

    Directory of Open Access Journals (Sweden)

    Paola Bonacini

    2017-01-01

    Full Text Available Let \\(\\Sigma=(X,\\mathcal{B}\\ be a \\(6\\-cycle system of order \\(v\\, so \\(v\\equiv 1,9\\mod 12\\. A \\(c\\-colouring of type \\(s\\ is a map \\(\\phi\\colon\\mathcal {B}\\rightarrow \\mathcal{C}\\, with \\(C\\ set of colours, such that exactly \\(c\\ colours are used and for every vertex \\(x\\ all the blocks containing \\(x\\ are coloured exactly with \\(s\\ colours. Let \\(\\frac{v-1}{2}=qs+r\\, with \\(q, r\\geq 0\\. \\(\\phi\\ is equitable if for every vertex \\(x\\ the set of the \\(\\frac{v-1}{2}\\ blocks containing \\(x\\ is partitioned in \\(r\\ colour classes of cardinality \\(q+1\\ and \\(s-r\\ colour classes of cardinality \\(q\\. In this paper we study bicolourings and tricolourings, for which, respectively, \\(s=2\\ and \\(s=3\\, distinguishing the cases \\(v=12k+1\\ and \\(v=12k+9\\. In particular, we settle completely the case of \\(s=2\\, while for \\(s=3\\ we determine upper and lower bounds for \\(c\\.

  3. Cell Cycle Phase Abnormalities Do Not Account for Disordered Proliferation in Barrett's Carcinogenesis

    Directory of Open Access Journals (Sweden)

    Pierre Lao-Sirieix

    2004-11-01

    Full Text Available Barrett's esophagus (BE epithelium is the precursor lesion for esophageal adenocarcinoma. Cell cycle proteins have been advocated as biomarkers to predict the malignant potential in BE. However, whether disruption of the cell cycle plays a causal role in Barrett's carcinogenesis is not clear. Specimens from the Barrett's dysplasia—carcinoma sequence were immunostained for cell cycle phase markers (cyclin D1 for G1; cyclin A for S, G2, and M; cytoplasmic cyclin B1 for G2; and phosphorylated histone 3 for M phase and expressed as a proportion of proliferating cells. Flow cytometric analysis of the cell cycle phase of prospective biopsies was also performed. The proliferation status of nondysplastic BE was similar to gastric antrum and D2, but the proliferative compartment extended to the luminal surface. In dysplastic samples, the number of proliferating cells correlated with the degree of dysplasia (P < .001. The overall levels of cyclins A and B1 correlated with the degree of dysplasia (P < .001. However, the cell cycle phase distribution measured with both immunostaining and flow cytometry was conserved during all stages of BE, dysplasia, and cancer. Hence, the increased proliferation seen in Barrett's carcinogenesis is due to abnormal cell cycle entry or exit, rather than a primary abnormality within the cell cycle.

  4. Angular-dependent light scattering from cancer cells in different phases of the cell cycle.

    Science.gov (United States)

    Lin, Xiaogang; Wan, Nan; Weng, Lingdong; Zhou, Yong

    2017-10-10

    Cancer cells in different phases of the cell cycle result in significant differences in light scattering properties. In order to harvest cancer cells in particular phases of the cell cycle, we cultured cancer cells through the process of synchronization. Flow cytometric analysis was applied to check the results of cell synchronization and prepare for light scattering measurements. Angular-dependent light scattering measurements of cancer cells arrested in the G1, S, and G2 phases have been performed. Based on integral calculations for scattering intensities from 5° to 10° and from 110° to 150°, conclusions have been reached. Clearly, the sizes of the cancer cells in different phases of the cell cycle dominated the forward scatter. Accompanying the increase of cell size with the progression of the cell cycle, the forward scattering intensity also increased. Meanwhile, the DNA content of cancer cells in every phase of the cell cycle is responsible for light scattering at large scatter angles. The higher the DNA content of cancer cells was, the greater the positive effect on the high-scattering intensity. As expected, understanding the relationships between the light scattering from cancer cells and cell cycles will aid in the development of cancer diagnoses. Also, it may assist in the guidance of antineoplastic drugs clinically.

  5. Susceptibility of Hep3B cells in different phases of cell cycle to tBid.

    Science.gov (United States)

    Ma, Shi-Hong; Chen, George G; Ye, Caiguo; Leung, Billy C S; Ho, Rocky L K; Lai, Paul B S

    2011-01-01

    tBid is a pro-apoptotic molecule. Apoptosis inducers usually act in a cell cycle-specific fashion. The aim of this study was to elucidate whether effect of tBid on hepatocellular carcinoma (HCC) Hep3B cells was cell cycle phase specific. We synchronized Hep3B cells at G0/G1, S or G2/M phases by chemicals or flow sorting and tested the susceptibility of the cells to recombinant tBid. Cell viability was measured by MTT assay and apoptosis by TUNEL. The results revealed that tBid primarily targeted the cells at G0/G1 phase of cell cycle, and it also increased the cells at the G2/M phase. 5-Fluorouracil (5-FU), on the other hand, arrested Hep3B cells at the G0/G1 phase, but significantly reduced cells at G2/M phase. The levels of cell cycle-related proteins and caspases were altered in line with the change in the cell cycle. The combination of tBid with 5-FU caused more cells to be apoptotic than either agent alone. Therefore, the complementary effect of tBid and 5-FU on different phases of the cell cycle may explain their synergistric effect on Hep3B cells. The elucidation of the phase-specific effect of tBid points to a possible therapeutic option that combines different phase specific agents to overcome resistance of HCC. Copyright © 2010 Elsevier B.V. All rights reserved.

  6. Enhancing power cycle efficiency for a supercritical Brayton cycle power system using tunable supercritical gas mixtures

    Science.gov (United States)

    Wright, Steven A.; Pickard, Paul S.; Vernon, Milton E.; Radel, Ross F.

    2017-08-29

    Various technologies pertaining to tuning composition of a fluid mixture in a supercritical Brayton cycle power generation system are described herein. Compounds, such as Alkanes, are selectively added or removed from an operating fluid of the supercritical Brayton cycle power generation system to cause the critical temperature of the fluid to move up or down, depending upon environmental conditions. As efficiency of the supercritical Brayton cycle power generation system is substantially optimized when heat is rejected near the critical temperature of the fluid, dynamically modifying the critical temperature of the fluid based upon sensed environmental conditions improves efficiency of such a system.

  7. Prospects and progress status of the Advanced Fuel Cycle System in Japan

    International Nuclear Information System (INIS)

    Namba, T.; Funasaka, H.; Nagaoki, Y.; Sagayama, Y.

    2004-01-01

    Feasibility study on commercialized FR cycle systems has been carried out by a joint team established within JNC with the participation of all parties concerned in Japan since July, 1999. This research program aims to clarify various perspectives for commercializing the FR cycle. This also will suggest development strategies that correspond flexibly to diverse future social needs in the 21. century. After the Phase I, Phase II stage started from April, 2001 for five years. In this stage the highly feasible candidate concepts for FR cycle systems screened in the previous step have been intensively studied by both design study and elemental process tests. In this paper, results of mid-term evaluation of these concepts for FR cycle systems will be summarized

  8. Prospects and progress status of the Advanced Fuel Cycle System in Japan

    Energy Technology Data Exchange (ETDEWEB)

    Namba, T.; Funasaka, H.; Nagaoki, Y.; Sagayama, Y

    2004-07-01

    Feasibility study on commercialized FR cycle systems has been carried out by a joint team established within JNC with the participation of all parties concerned in Japan since July, 1999. This research program aims to clarify various perspectives for commercializing the FR cycle. This also will suggest development strategies that correspond flexibly to diverse future social needs in the 21. century. After the Phase I, Phase II stage started from April, 2001 for five years. In this stage the highly feasible candidate concepts for FR cycle systems screened in the previous step have been intensively studied by both design study and elemental process tests. In this paper, results of mid-term evaluation of these concepts for FR cycle systems will be summarized.

  9. Label-free cell-cycle analysis by high-throughput quantitative phase time-stretch imaging flow cytometry

    Science.gov (United States)

    Mok, Aaron T. Y.; Lee, Kelvin C. M.; Wong, Kenneth K. Y.; Tsia, Kevin K.

    2018-02-01

    Biophysical properties of cells could complement and correlate biochemical markers to characterize a multitude of cellular states. Changes in cell size, dry mass and subcellular morphology, for instance, are relevant to cell-cycle progression which is prevalently evaluated by DNA-targeted fluorescence measurements. Quantitative-phase microscopy (QPM) is among the effective biophysical phenotyping tools that can quantify cell sizes and sub-cellular dry mass density distribution of single cells at high spatial resolution. However, limited camera frame rate and thus imaging throughput makes QPM incompatible with high-throughput flow cytometry - a gold standard in multiparametric cell-based assay. Here we present a high-throughput approach for label-free analysis of cell cycle based on quantitative-phase time-stretch imaging flow cytometry at a throughput of > 10,000 cells/s. Our time-stretch QPM system enables sub-cellular resolution even at high speed, allowing us to extract a multitude (at least 24) of single-cell biophysical phenotypes (from both amplitude and phase images). Those phenotypes can be combined to track cell-cycle progression based on a t-distributed stochastic neighbor embedding (t-SNE) algorithm. Using multivariate analysis of variance (MANOVA) discriminant analysis, cell-cycle phases can also be predicted label-free with high accuracy at >90% in G1 and G2 phase, and >80% in S phase. We anticipate that high throughput label-free cell cycle characterization could open new approaches for large-scale single-cell analysis, bringing new mechanistic insights into complex biological processes including diseases pathogenesis.

  10. Life Cycle Thinking, Measurement and Management for Food System Sustainability.

    Science.gov (United States)

    Pelletier, Nathan

    2015-07-07

    Food systems critically contribute to our collective sustainability outcomes. Improving food system sustainability requires life cycle thinking, measurement and management strategies. This article reviews the status quo and future prospects for bringing life cycle approaches to food system sustainability to the fore.

  11. Cycle-to-cycle control of swing phase of paraplegic gait induced by surface electrical stimulation

    NARCIS (Netherlands)

    Franken, H.M.; Franken, H.M.; Veltink, Petrus H.; Baardman, G.; Redmeijer, R.A.; Boom, H.B.K.

    1995-01-01

    Parameterised swing phase of gait in paraplegics was obtained using surface electrical stimulation of the hip flexors, hamstrings and quadriceps; the hip flexors were stimulated to obtain a desired hip angle range, the hamstrings to provide foot clearance in the forward swing, and the quadriceps to

  12. Cycle for innovative nuclear Gen 4. systems=

    International Nuclear Information System (INIS)

    2004-01-01

    In the framework of the development of nuclear systems of the 4. generation, the preliminary and schematic reprocessing goals are a cleaning of fission products without a priori separation of the different actinides. The objective of the workshop is to exchange information about the potential efficiency of innovative fuel processing treatments in order to evaluate the impact of impurities on the design of the fuel during its re-fabrication and re-introduction inside the reactor, and on the materials and systems. This document gathers the slides of the 18 presentations given at this workshop: 1 - from the PWR fuel to the closed cycle fast spectrum concepts of generation 4 systems (P. Anzieu, F. Carre, Ph. Brossard, M. Delpech); 2 - the double strata scenarios: objectives and characteristics (S. David and F. Varaine); 3 - why a molten salts thorium file (D. Heuer); 4 - the common 'molten salts' research program of the CNRS (D. Heuer, S. Sanchez); 5 - the hydro-metallurgical reprocessing, the knowledge gained and the statuses of the 5. PCRD, synthesis of the OECD works (C. Madic); 6 - pyro-chemistry: Pyropep status (H. Boussier); 7 - technological bolts identified during the Most project of the 5. PCRD (C. Renault, Ch. Le Brun, M. Delpech and C. Garzenne); 8 - the molten salt reactor concept and its reprocessing options, expected efficiencies (L. Mathieu); 9 - methodology of evaluation of pyro-chemical fuel reprocessing schemes (H. Boussier); 10 - molten salt reactor, design-aided tools for the reactor and the reprocessing plant (O. Gastaldi, E. Walle, O. Koberl, D. Lecarpentier); 11 - status of CEA's prospective studies for the front-end of the fuel reprocessing process/dry ways (S. Bourg); 12 - results of activity coefficient measurements in liquid metals (J. Finne, E. Walle, G. Picard, S. Sanchez and O. Conocar); 13 - potentialities of electrolytic separation and liquid-liquid extraction processes (molten salts/molten metal) for the multi-recycling of actinides (J

  13. Promising fast reactor systems in the feasibility study on commercialized FR cycle system

    International Nuclear Information System (INIS)

    Sakamoto, Y.; Kotake, S.; Enuma, Y.; Sagayama, Y.; Nishikawa, A.; Ando, M.

    2005-01-01

    The Feasibility Study on Commercialized Fast Reactor (FR) Cycle Systems is under way in order to propose prominent FR cycle systems that will respond to the diverse needs of society in the future. The design studies on various FR system concepts have been achieved and then the evaluations of potential to achieve the development targets have been carried out. Crucial issues have been found out for each FR system concept and their development plans for the key technologies are summarized as the roadmap. The characteristics and the differences in performances have been investigated. The crucial issues and the development periods have been clarified. Further investigation is now in progress. The promising concept will be proposed based on result of comparative evaluation at the end of the Phase II study. (authors)

  14. Analysis of interconnecting energy systems over a synchronized life cycle

    International Nuclear Information System (INIS)

    Nian, Victor

    2016-01-01

    Highlights: • A methodology is developed for evaluating a life cycle of interconnected systems. • A new concept of partial temporal boundary is introduced via quantitative formulation. • The interconnecting systems are synchronized through the partial temporal boundary. • A case study on the life cycle of the coal–uranium system is developed. - Abstract: Life cycle analysis (LCA) using the process chain analysis (PCA) approach has been widely applied to energy systems. When applied to an individual energy system, such as coal or nuclear electricity generation, an LCA–PCA methodology can yield relatively accurate results with its detailed process representation based on engineering data. However, there are fundamental issues when applying conventional LCA–PCA methodology to a more complex life cycle, namely, a synchronized life cycle of interconnected energy systems. A synchronized life cycle of interconnected energy systems is established through direct interconnections among the processes of different energy systems, and all interconnecting systems are bounded within the same timeframe. Under such a life cycle formation, there are some major complications when applying conventional LCA–PCA methodology to evaluate the interconnecting energy systems. Essentially, the conventional system and boundary formulations developed for a life cycle of individual energy system cannot be directly applied to a life cycle of interconnected energy systems. To address these inherent issues, a new LCA–PCA methodology is presented in this paper, in which a new concept of partial temporal boundary is introduced to synchronize the interconnecting energy systems. The importance and advantages of these new developments are demonstrated through a case study on the life cycle of the coal–uranium system.

  15. A New Dynamic Model for Nuclear Fuel Cycle System Analysis

    International Nuclear Information System (INIS)

    Choi, Sungyeol; Ko, Won Il

    2014-01-01

    The evaluation of mass flow is a complex process where numerous parameters and their complex interaction are involved. Given that many nuclear power countries have light and heavy water reactors and associated fuel cycle technologies, the mass flow analysis has to consider a dynamic transition from the open fuel cycle to other cycles over decades or a century. Although an equilibrium analysis provides insight concerning the end-states of fuel cycle transitions, it cannot answer when we need specific management options, whether the current plan can deliver these options when needed, and how fast the equilibrium can be achieved. As a pilot application, the government brought several experts together to conduct preliminary evaluations for nuclear fuel cycle options in 2010. According to Table 1, they concluded that the closed nuclear fuel cycle has long-term advantages over the open fuel cycle. However, it is still necessary to assess these options in depth and to optimize transition paths of these long-term options with advanced dynamic fuel cycle models. A dynamic simulation model for nuclear fuel cycle systems was developed and its dynamic mass flow analysis capability was validated against the results of existing models. This model can reflects a complex combination of various fuel cycle processes and reactor types, from once-through to multiple recycling, within a single nuclear fuel cycle system. For the open fuel cycle, the results of the developed model are well matched with the results of other models

  16. Towards cycle-accurate performance predictions for real-time embedded systems

    NARCIS (Netherlands)

    Triantafyllidis, K.; Bondarev, E.; With, de P.H.N.; Arabnia, H.R.; Deligiannidis, L.; Jandieri, G.

    2013-01-01

    In this paper we present a model-based performance analysis method for component-based real-time systems, featuring cycle-accurate predictions of latencies and enhanced system robustness. The method incorporates the following phases: (a) instruction-level profiling of SW components, (b) modeling the

  17. Supporting innovation. International Project on Innovative Nuclear Reactors and Fuel Cycles moves into first phase

    International Nuclear Information System (INIS)

    Gowin, Peter J.; Kupitz, Juergen

    2001-01-01

    energy needs and environmental impact. In order for nuclear energy to play a meaningful role in the global energy supply in the foreseeable future, innovative approaches will be required to address concerns about economic competitiveness, safety, waste and potential proliferation risks.' INPRO's objectives, as defined in the Terms of Reference, are: to help to ensure that nuclear energy is available to contribute in fulfilling, in a sustainable manner, energy needs in the 21st century; to bring together all interested Member States, both technology holders and technology users, to consider jointly the international and national actions required to achieve desired innovations in nuclear reactors and fuel cycles that use sound and economically competitive technology, are based - to the extent possible - on systems with inherent safety features and minimise the risk of proliferation and the impact on the environment; to create a process that involves all relevant stake holders that will have an impact on, draw from, and complement the activities of existing institutions, as well as ongoing initiatives at the national and international level. INPRO is an Agencywide project, with contributions from all relevant IAEA Departments within available resources. The Project will be implemented in two phases. Phase I was initiated in early 2001 and is planned to run to 2003. In the first phase, work will proceed in five subject areas recognized as important for the future development of nuclear energy technology, and on two parallel tracks. Upon successful completion of INPRO's first phase, taking into account advice from the Steering Committee, and with the approval of participating Member States, a second phase of INPRO may be initiated. Drawing on the results from the first phase, it would be directed at: examining in the context of available technologies the feasibility of commencing an international project; and identifying technologies which might be appropriate for

  18. Nuclear Fuel Cycle System Analysis (II)

    Energy Technology Data Exchange (ETDEWEB)

    Ko, Won Il; Kwon, Eun Ha; Yoon, Ji Sup; Park, Seong Won

    2007-04-15

    As a nation develops strategies that provide nuclear energy while meeting its various objectives, it must begin with identification of a fuel cycle option that can be best suitable for the country. For such a purpose, this paper takes four different fuel cycle options that are likely adopted by the Korean government, considering the current status of nuclear power generation and the 2nd Comprehensive Nuclear Energy Promotion Plan (CNEPP) - Once-through Cycle, DUPIC Recycle, Thermal Reactor Recycle and GEN-IV Recycle. The paper then evaluates each option in terms of sustainability, environment-friendliness, proliferation-resistance, economics and technologies. Like all the policy decision, however, a nuclear fuel cycle option can not be superior in all aspects of sustainability, environment-friendliness, proliferation-resistance, economics, technologies and so on, which makes the comparison of the options extremely complicated. Taking this into consideration, the paper analyzes all the four fuel cycle options using the Multi-Attribute Utility Theory (MAUT) and the Analytic Hierarchy Process (AHP), methods of Multi-Attribute Decision Making (MADM), that support systematical evaluation of the cases with multi- goals or criteria and that such goals are incompatible with each other. The analysis shows that the GEN-IV Recycle appears to be most competitive.

  19. Prospects of the use of nanofluids as working fluids for organic Rankine cycle power systems

    DEFF Research Database (Denmark)

    Mondejar, Maria E.; Andreasen, Jesper G.; Regidor, Maria

    2017-01-01

    The search of novel working fluids for organic Rankine cycle power systems is driven by the recent regulations imposing additional phase-out schedules for substances with adverse environmental characteristics. Recently, nanofluids (i.e. colloidal suspensions of nanoparticles in fluids) have been...... suggested as potential working fluids for organic Rankine cycle power systems due to their enhanced thermal properties, potentially giving advantages with respect to the design of the components and the cycle performance. Nevertheless, a number of challenges concerning the use of nanofluids must...... the prospects of using nanofluids as working fluids for organic Rankine cycle power systems. As a preliminary study, nanofluids consisting of a homogenous and stable mixture of different nanoparticles types and a selected organic fluid are simulated on a case study organic Rankine cycle unit for waste heat...

  20. Executive overview and introduction to the SMAP information system life-cycle and documentation standards

    Science.gov (United States)

    1989-01-01

    An overview of the five volume set of Information System Life-Cycle and Documentation Standards is provided with information on its use. The overview covers description, objectives, key definitions, structure and application of the standards, and document structure decisions. These standards were created to provide consistent NASA-wide structures for coordinating, controlling, and documenting the engineering of an information system (hardware, software, and operational procedures components) phase by phase.

  1. Nuclear Fuel Cycle System Analysis (I)

    Energy Technology Data Exchange (ETDEWEB)

    Ko, Won Il; Kwon, Eun Ha; Kim, Ho Dong; Yoon, Ji Sup; Park, Seong Won

    2006-12-15

    As a nation develops strategies that provide nuclear energy while meeting its various objectives, it must begin with identification of a fuel cycle option that can be best suitable for the country. For such a purpose, this paper takes four different fuel cycle options - Once-through Cycle, DUPIC Recycle, Thermal Reactor Recycle and GEN-IV Recycle, and evaluates each option in terms of sustainability, environment-friendliness, proliferation-resistance and economics. The analysis shows that the GEN-IV Recycle appears to have an advantage in terms of sustainability, environment-friendliness and long-term proliferation-resistance, while it is expected to be more economically competitive, if uranium ore prices increase or costs of pyroprocessing and fuel fabrication decrease.

  2. Relationship between geomagnetic classes’ activity phases and their occurrence during the sunspot cycle

    Directory of Open Access Journals (Sweden)

    Frédéric Ouattara

    2009-06-01

    Full Text Available Four well known geomagnetic classes of activity such as quiet days activity, fluctuating activity, recurrent activity
    and shock activity time occurrences have been determined not only by using time profile of sunspot number
    Rz but also by using aa index values.
    We show that recurrent wind stream activity and fluctuating activity occur in opposite phase and slow solar wind
    activity during minimum phase and shock activity at the maximum phase.
    It emerges from this study that fluctuating activity precedes the sunspot cycle by π/2 and the latter also precedes
    recurrent activity by π/2. Thus in the majority the activities do not happen at random; the sunspot cycle starts
    with quiet days activity, continues with fluctuating activity and during its maximum phase arrives shock activity.
    The descending phase is characterized by the manifestation of recurrent wind stream activity.

  3. Default cycle phases determined after modifying discrete DNA sequences in plant cells

    International Nuclear Information System (INIS)

    Sans, J.; Leyton, C.

    1997-01-01

    After bromosubstituting DNA sequences replicated in the first, second, or third part of the S phase, in Allium cepa L. meristematic cells, radiation at 313 nm wavelength under anoxia allowed ascription of different sequences to both the positive and negative regulation of some cycle phase transitions. The present report shows that the radiation forced cells in late G 1 phase to advance into S, while those in G 2 remained in G 2 and cells in prophase returned to G 2 when both sets of sequences involved in the positive and negative controls were bromosubstituted and later irradiated. In this way, not only G 2 but also the S phase behaved as cycle phases where cells accumulated by default when signals of different sign functionally cancelled out. The treatment did not halt the rates of replication or transcription of plant bromosubstituted DNA. The irradiation under hypoxia apparently prevents the binding of regulatory proteins to Br-DNA. (author)

  4. Bifurcation of limit cycles for cubic reversible systems

    Directory of Open Access Journals (Sweden)

    Yi Shao

    2014-04-01

    Full Text Available This article is concerned with the bifurcation of limit cycles of a class of cubic reversible system having a center at the origin. We prove that this system has at least four limit cycles produced by the period annulus around the center under cubic perturbations

  5. Environmental systems analysis of biogas systems-Part I: Fuel-cycle emissions

    International Nuclear Information System (INIS)

    Boerjesson, Pal; Berglund, Maria

    2006-01-01

    Fuel-cycle emissions of carbon dioxide (CO 2 ), carbon oxide (CO), nitrogen oxides (NO x ), sulphur dioxide (SO 2 ), hydrocarbons (HC), methane (CH 4 ), and particles are analysed from a life-cycle perspective for different biogas systems based on six different raw materials. The gas is produced in large- or farm-scale biogas plants, and is used in boilers for heat production, in turbines for co-generation of heat and electricity, or as a transportation fuel in light- and heavy-duty vehicles. The analyses refer mainly to Swedish conditions. The levels of fuel-cycle emissions vary greatly among the biogas systems studied, and are significantly affected by the properties of the raw material digested, the energy efficiency of the biogas production, and the status of the end-use technology. For example, fuel-cycle emission may vary by a factor of 3-4, and for certain gases by up to a factor of 11, between two biogas systems that provide an equivalent energy service. Extensive handling of raw materials, e.g. ley cropping or collection of waste-products such as municipal organic waste, is often a significant source of emissions. Emission from the production phase of the biogas exceeds the end-use emissions for several biogas systems and for specific emissions. Uncontrolled losses of methane, e.g. leakages from stored digestates or from biogas upgrading, increase the fuel-cycle emissions of methane considerably. Thus, it is necessary to clearly specify the biogas production system and end-use technology being studied in order to be able to produce reliable and accurate data on fuel-cycle emission

  6. Effect of duty-cycles on the air plasma gas-phase of dielectric barrier discharges

    Science.gov (United States)

    Barni, R.; Biganzoli, I.; Dell'Orto, E. C.; Riccardi, C.

    2015-10-01

    An experimental investigation concerning the effects of a duty-cycle in the supply of a dielectric barrier discharge in atmospheric pressure air has been performed. Electrical characteristics of the discharge have been measured, focusing mainly on the statistical properties of the current filaments and on dielectric surface charging, both affected by the frequent repetition of breakdown imposed by the duty-cycle. Information on the gas-phase composition was gathered too. In particular, a strong enhancement in the ozone formation rate is observed when suitable long pauses separate the active discharge phases. A simulation of the chemical kinetics in the gas-phase, based on a simplified discharge modeling, is briefly described in order to shed light on the observed increase in ozone production. The effect of a duty-cycle on surface modification of polymeric films in order to increase their wettability has been investigated too.

  7. Impact of gender and menstrual cycle phase on plasma cytokine concentrations.

    LENUS (Irish Health Repository)

    O'Brien, Sinead M

    2012-02-03

    OBJECTIVE: The lifetime prevalence of major depression is twice as high in females as in males. Depression is known to increase at periods where there are changes in gonadal hormones. We examined pro- and anti-inflammatory cytokine levels during the normal menstrual cycle of healthy females compared to similar time points in healthy males. METHODS: Plasma concentrations of interleukin (IL)-4, IL-6, IL-8, IL-10, tumour necrosis factor-alpha (TNF-alpha) and soluble IL-6 receptor (sIL-6R) were measured with enzyme-linked immunosorbent assays in healthy females during the normal ovulatory menstrual cycle and also in males at similar time points. RESULTS: The luteal phase of the menstrual cycle is associated with increased production of sIL-6R, IL-4 and TNF-alpha compared to the early follicular phase. No change was observed in IL-6, IL-8 and IL-10 concentration throughout the menstrual cycle. We found IL-4 positively correlated with oestrogen while TNF-alpha positively correlated with progesterone. Females were found to have significantly higher concentrations of TNF-alpha and sIL-6R across all phases of the menstrual cycle, compared to males across similar time points. CONCLUSION: The normal menstrual cycle is associated with increased production of sIL-6R, IL-4 and TNF-alpha in the luteal phase compared to the early follicular phase. Females have significantly higher concentrations of sIL-6R and TNF-alpha at all time points across the menstrual cycle than males.

  8. Closed-cycle cooling systems for nuclear power plants

    International Nuclear Information System (INIS)

    Santini, Lorenzo

    2006-01-01

    The long experience in the field of closed-cycle cooling systems and high technological level of turbo machines and heat exchangers concurs to believe in the industrial realizability of nuclear systems of high thermodynamic efficiency and intrinsic safety [it

  9. Circadian Clock Synchronization of the Cell Cycle in Zebrafish Occurs through a Gating Mechanism Rather Than a Period-phase Locking Process.

    Science.gov (United States)

    Laranjeiro, Ricardo; Tamai, T Katherine; Letton, William; Hamilton, Noémie; Whitmore, David

    2018-04-01

    Studies from a number of model systems have shown that the circadian clock controls expression of key cell cycle checkpoints, thus providing permissive or inhibitory windows in which specific cell cycle events can occur. However, a major question remains: Is the clock actually regulating the cell cycle through such a gating mechanism or, alternatively, is there a coupling process that controls the speed of cell cycle progression? Using our light-responsive zebrafish cell lines, we address this issue directly by synchronizing the cell cycle in culture simply by changing the entraining light-dark (LD) cycle in the incubator without the need for pharmacological intervention. Our results show that the cell cycle rapidly reentrains to a shifted LD cycle within 36 h, with changes in p21 expression and subsequent S phase timing occurring within the first few hours of resetting. Reentrainment of mitosis appears to lag S phase resetting by 1 circadian cycle. The range of entrainment of the zebrafish clock to differing LD cycles is large, from 16 to 32 hour periods. We exploited this feature to explore cell cycle entrainment at both the population and single cell levels. At the population level, cell cycle length is shortened or lengthened under corresponding T-cycles, suggesting that a 1:1 coupling mechanism is capable of either speeding up or slowing down the cell cycle. However, analysis at the single cell level reveals that this, in fact, is not true and that a gating mechanism is the fundamental method of timed cell cycle regulation in zebrafish. Cell cycle length at the single cell level is virtually unaltered with varying T-cycles.

  10. Phases, phase equilibria, and phase rules in low-dimensional systems

    International Nuclear Information System (INIS)

    Frolov, T.; Mishin, Y.

    2015-01-01

    We present a unified approach to thermodynamic description of one, two, and three dimensional phases and phase transformations among them. The approach is based on a rigorous definition of a phase applicable to thermodynamic systems of any dimensionality. Within this approach, the same thermodynamic formalism can be applied for the description of phase transformations in bulk systems, interfaces, and line defects separating interface phases. For both lines and interfaces, we rigorously derive an adsorption equation, the phase coexistence equations, and other thermodynamic relations expressed in terms of generalized line and interface excess quantities. As a generalization of the Gibbs phase rule for bulk phases, we derive phase rules for lines and interfaces and predict the maximum number of phases than may coexist in systems of the respective dimensionality

  11. Long-term variations in the geomagnetic activity level Part II: Ascending phases of sunspot cycles

    Directory of Open Access Journals (Sweden)

    V. Mussino

    1994-08-01

    Full Text Available Monthly averages of the Helsinki Ak-values have been reduced to the equivalent aa-indices to extend the aa-data set back to 1844. A periodicity of about five cycles was found for the correlation coefficient (r between geomagnetic indices and sunspot numbers for the ascending phases of sunspot cycles 9 to 22, confirming previous findings based on a minor number of sunspot cycles. The result is useful to researchers in topics related to solar-terrestrial physics, particularly for the interpretation of long-term trends in geomagnetic activity during the past, and to forecast geomagnetic activity levels in the future.

  12. G2 phase arrest of cell cycle induced by ionizing radiation

    International Nuclear Information System (INIS)

    Liu Guangwei; Gong Shouliang

    2002-01-01

    The exposure of mammalian cells to X rays results in the prolongation of the cell cycle, including the delay or the arrest in G 1 , S and G 2 phase. The major function of G 1 arrest may be to eliminate the cells containing DNA damage and only occurs in the cells with wild type p53 function whereas G 2 arrest following ionizing radiation has been shown to be important in protecting the cells from death and occurs in all cells regardless of p53 status. So the study on G 2 phase arrest of the cell cycle induced by ionizing radiation has currently become a focus at radiobiological fields

  13. Life-cycle analysis of renewable energy systems

    DEFF Research Database (Denmark)

    Sørensen, Bent

    1994-01-01

    An imlementation of life-cycle analysis (LCA) for energy systems is presented and applied to two renewable energy systems (wind turbines and building-integrated photovoltaic modules) and compared with coal plants......An imlementation of life-cycle analysis (LCA) for energy systems is presented and applied to two renewable energy systems (wind turbines and building-integrated photovoltaic modules) and compared with coal plants...

  14. Transvaginal sonographic evaluation at different menstrual cycle phases in diagnosis of uterine lesions

    Directory of Open Access Journals (Sweden)

    Hajishaiha M

    2011-10-01

    Full Text Available Masomeh Hajishaiha1, Mohammad Ghasemi-rad2, Nazila Karimpour1, Nikol Mladkova3, Farzaneh Boromand11Department of Gynecology, 2Student Research Committee (SRC, Urmia University of Medical Sciences, Urmia, Islamic Republic of Iran; 3Institute of Cell and Molecular Science, London, UKPurpose: Intrauterine lesions (IULs are a common finding in women of reproductive age, particularly infertile women. Transvaginal sonography (TVS is a popular tool for IUL detection, but there are conflicting data with respect to its accuracy.Methods: Five hundred and six women were enrolled into the study. Of these, 496 underwent hysterosalpingography and subsequent TVS six different times during the course of their menstrual cycle. If a lesion was detected, it was further evaluated by sonohysterography (SHG and hysteroscopy.Results: Of 496 women, 41 were shown to have IULs by TVS and those lesions were confirmed in 39 by SHG and hysteroscopy. All 39 lesions were detectable during the ovulatory and early luteal phase (days 16–19 of the menstrual cycle. Accuracy of TVS during different phases was largely dependent on the size of the lesion. TVS falsely detected two lesions and missed fine adhesions in two patients.Conclusion: Accuracy of TVS in detection of IULs is highly dependent on the menstrual cycle phase, with the ovulatory and early luteal phase being the optimal time for this examination.Keywords: menstrual cycle phase, space occupying lesions, transvaginal sonography

  15. Operating cycle optimization for a Magnus effect-based airborne wind energy system

    International Nuclear Information System (INIS)

    Milutinović, Milan; Čorić, Mirko; Deur, Joško

    2015-01-01

    Highlights: • Operating cycle of a Magnus effect-based AWE system has been optimized. • The cycle trajectory should be vertical and far from the ground based generator. • Vertical trajectory provides high pulling force that drives the generator. • Large distance from the generator is required for the feasibility of the cycle. - Abstract: The paper presents a control variables optimization study for an airborne wind energy production system. The system comprises an airborne module in the form of a buoyant, rotating cylinder, whose rotation in a wind stream induces the Magnus effect-based aerodynamic lift. Through a tether, the airborne module first drives the generator fixed on the ground, and then the generator becomes a motor that lowers the airborne module. The optimization is aimed at maximizing the average power produced at the generator during a continuously repeatable operating cycle. The control variables are the generator-side rope force and the cylinder rotation speed. The optimization is based on a multi-phase problem formulation, where operation is divided into ascending and descending phases, with free boundary conditions and free cycle duration. The presented simulation results show that significant power increase can be achieved by using the obtained optimal operating cycle instead of the initial, empirically based operation control strategy. A brief analysis is also given to provide a physical interpretation of the optimal cycle results

  16. Innovation Cycles Concerning Strategic Planning of Product-Service-Systems

    OpenAIRE

    Hepperle, Clemens;Mörtl, Markus;Lindemann, Udo

    2017-01-01

    This paper proposes a research program for identifying, understanding and describing innovation cycles concerning strategic planning of product-service-systems. A general overview about the background of cycle management in innovation processes, which the proposed research program is part of, is given before focusing cycles concerning strategic planning. As companies offer more and more complex products in order to satisfy market needs, the innovation process of such products becomes also mor...

  17. Technology verification phase. Dynamic isotope power system. Final report

    International Nuclear Information System (INIS)

    Halsey, D.G.

    1982-01-01

    The Phase I requirements of the Kilowatt Isotope Power System (KIPS) program were to make a detailed Flight System Conceptual Design (FSCD) for an isotope fueled organic Rankine cycle power system and to build and test a Ground Demonstration System (GDS) which simulated as closely as possible the operational characteristics of the FSCD. The activities and results of Phase II, the Technology Verification Phase, of the program are reported. The objectives of this phase were to increase system efficiency to 18.1% by component development, to demonstrate system reliability by a 5000 h endurance test and to update the flight system design. During Phase II, system performance was improved from 15.1% to 16.6%, an endurance test of 2000 h was performed while the flight design analysis was limited to a study of the General Purpose Heat Source, a study of the regenerator manufacturing technique and analysis of the hardness of the system to a laser threat. It was concluded from these tests that the GDS is basically prototypic of a flight design; all components necessary for satisfactory operation were demonstrated successfully at the system level; over 11,000 total h of operation without any component failure attested to the inherent reliability of this type of system; and some further development is required, specifically in the area of performance

  18. Technology verification phase. Dynamic isotope power system. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Halsey, D.G.

    1982-03-10

    The Phase I requirements of the Kilowatt Isotope Power System (KIPS) program were to make a detailed Flight System Conceptual Design (FSCD) for an isotope fueled organic Rankine cycle power system and to build and test a Ground Demonstration System (GDS) which simulated as closely as possible the operational characteristics of the FSCD. The activities and results of Phase II, the Technology Verification Phase, of the program are reported. The objectives of this phase were to increase system efficiency to 18.1% by component development, to demonstrate system reliability by a 5000 h endurance test and to update the flight system design. During Phase II, system performance was improved from 15.1% to 16.6%, an endurance test of 2000 h was performed while the flight design analysis was limited to a study of the General Purpose Heat Source, a study of the regenerator manufacturing technique and analysis of the hardness of the system to a laser threat. It was concluded from these tests that the GDS is basically prototypic of a flight design; all components necessary for satisfactory operation were demonstrated successfully at the system level; over 11,000 total h of operation without any component failure attested to the inherent reliability of this type of system; and some further development is required, specifically in the area of performance. (LCL)

  19. Induction of Phase Variation Events in the Life Cycle of the Marine Coccolithophorid Emiliania huxleyi

    Science.gov (United States)

    Laguna, Richard; Romo, Jesus; Read, Betsy A.; Wahlund, Thomas M.

    2001-01-01

    Emiliania huxleyi is a unicellular marine alga that is considered to be the world's major producer of calcite. The life cycle of this alga is complex and is distinguished by its ability to synthesize exquisitely sculptured calcium carbonate cell coverings known as coccoliths. These structures have been targeted by materials scientists for applications relating to the chemistry of biomedical materials, robust membranes for high-temperature separation technology, lightweight ceramics, and semiconductor design. To date, however, the molecular and biochemical events controlling coccolith production have not been determined. In addition, little is known about the life cycle of E. huxleyi and the environmental and physiological signals triggering phase switching between the diploid and haploid life cycle stages. We have developed laboratory methods for inducing phase variation between the haploid (S-cell) and diploid (C-cell) life cycle stages of E. huxleyi. Plating E. huxleyi C cells on solid media was shown to induce phase switching from the C-cell to the S-cell life cycle stage, the latter of which has been maintained for over 2 years under these conditions. Pure cultures of S cells were obtained for the first time. Laboratory conditions for inducing phase switching from the haploid stage to the diploid stage were also established. Regeneration of the C-cell stage from pure cultures of S cells followed a predictable pattern involving formation of large aggregations of S cells and the subsequent production of cultures consisting predominantly of diploid C cells. These results demonstrate the ability to manipulate the life cycle of E. huxleyi under controlled laboratory conditions, providing us with powerful tools for the development of genetic techniques for analysis of coccolithogenesis and for investigating the complex life cycle of this important marine alga. PMID:11525973

  20. Space Transportation System Availability Relationships to Life Cycle Cost

    Science.gov (United States)

    Rhodes, Russel E.; Donahue, Benjamin B.; Chen, Timothy T.

    2009-01-01

    Future space transportation architectures and designs must be affordable. Consequently, their Life Cycle Cost (LCC) must be controlled. For the LCC to be controlled, it is necessary to identify all the requirements and elements of the architecture at the beginning of the concept phase. Controlling LCC requires the establishment of the major operational cost drivers. Two of these major cost drivers are reliability and maintainability, in other words, the system's availability (responsiveness). Potential reasons that may drive the inherent availability requirement are the need to control the number of unique parts and the spare parts required to support the transportation system's operation. For more typical space transportation systems used to place satellites in space, the productivity of the system will drive the launch cost. This system productivity is the resultant output of the system availability. Availability is equal to the mean uptime divided by the sum of the mean uptime plus the mean downtime. Since many operational factors cannot be projected early in the definition phase, the focus will be on inherent availability which is equal to the mean time between a failure (MTBF) divided by the MTBF plus the mean time to repair (MTTR) the system. The MTBF is a function of reliability or the expected frequency of failures. When the system experiences failures the result is added operational flow time, parts consumption, and increased labor with an impact to responsiveness resulting in increased LCC. The other function of availability is the MTTR, or maintainability. In other words, how accessible is the failed hardware that requires replacement and what operational functions are required before and after change-out to make the system operable. This paper will describe how the MTTR can be equated to additional labor, additional operational flow time, and additional structural access capability, all of which drive up the LCC. A methodology will be presented that

  1. Influence of menstrual cycle phase on pulmonary function in asthmatic athletes.

    Science.gov (United States)

    Stanford, Kristin I; Mickleborough, Timothy D; Ray, Shahla; Lindley, Martin R; Koceja, David M; Stager, Joel M

    2006-04-01

    The main aim of this study was to investigate whether there is a relationship between menstrual cycle phase and exercise-induced bronchoconstriction (EIB) in female athletes with mild atopic asthma. Seven eumenorrheic subjects with regular 28-day menstrual cycles were exercised to volitional exhaustion on day 5 [mid-follicular (FOL)] and day 21 [mid-luteal (LUT)] of their menstrual cycle. Pulmonary function tests were conducted pre- and post-exercise. The maximal percentage decline in post-exercise forced expiratory volume in 1 s (FEV(1)) and forced expiratory flow from 25 to 75% of forced vital capacity (FEF(25-75%)) was significantly greater (Pphase) (-17.35+/-2.32 and -26.28+/-6.04%, respectively), when salivary progesterone concentration was highest, compared to day 5 (mid-FOL phase) (-12.81+/-3.35 and -17.23+/-8.20%, respectively), when salivary progesterone concentration was lowest. The deterioration in the severity of EIB during the mid-LUT phase was accompanied by worsening asthma symptoms and increased bronchodilator use. There was a negative correlation between the percent change in pre- to post-exercise FEV(1) and salivary progesterone concentration. However, no such correlation was found between salivary estradiol and the percentage change in pre- to post-exercise FEV(1). This study has shown for the first time that menstrual cycle phase is an important determinant of the severity of EIB in female athletes with mild atopic asthma. Female asthmatic athletes may need to adjust their training and competition schedules to their menstrual cycle and to consider the potential negative effects of the LUT phase of the menstrual cycle on exercise performance.

  2. Organic Rankine Kilowatt Isotope Power System. Final phase I report

    International Nuclear Information System (INIS)

    1978-01-01

    On 1 August 1975 under Department of Energy Contract EN-77-C-02-4299, Sundstrand Energy Systems commenced development of a Kilowatt Isotope Power System (KIPS) directed toward satisfying the higher power requirements of satellites of the 1980s and beyond. The KIPS is a 238 PuO 2 fueled organic Rankine cycle turbine power system which will provide design output power in the range of 500 to 2000 W/sub (e)/ with a minimum of system changes. The principal objectives of the Phase 1 development effort were to: conceptually design a flight system; design a Ground Demonstration System (GDS) that is prototypic of the flight system in order to prove the feasibility of the flight system design; fabricate and assemble the GDS; and performance and endurance test the GDS using electric heaters in lieu of the isotope heat source. Results of the work performed under the Phase 1 contract to 1 July 1978 are presented

  3. Nonlinear transport of dynamic system phase space

    International Nuclear Information System (INIS)

    Xie Xi; Xia Jiawen

    1993-01-01

    The inverse transform of any order solution of the differential equation of general nonlinear dynamic systems is derived, realizing theoretically the nonlinear transport for the phase space of nonlinear dynamic systems. The result is applicable to general nonlinear dynamic systems, with the transport of accelerator beam phase space as a typical example

  4. Perform Thermodynamics Measurements on Fuel Cycle Case Study Systems

    Energy Technology Data Exchange (ETDEWEB)

    Martin, Leigh R. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2014-09-01

    This document was prepared to meet FCR&D level 3 milestone M3FT-14IN0304022, “Perform Thermodynamics Measurements on Fuel Cycle Case Study Systems.” This work was carried out under the auspices of the Thermodynamics and Kinetics FCR&D work package. This document reports preliminary work in support of determining the thermodynamic parameters for the ALSEP process. The ALSEP process is a mixed extractant system comprised of a cation exchanger 2-ethylhexyl-phosphonic acid mono-2-ethylhexyl ester (HEH[EHP]) and a neutral solvating extractant N,N,N’,N’-tetraoctyldiglycolamide (TODGA). The extractant combination produces complex organic phase chemistry that is challenging for traditional measurement techniques. To neutralize the complexity, temperature dependent solvent extraction experiments were conducted with neat TODGA and scaled down concentrations of the ALSEP formulation to determine the enthalpies of extraction for the two conditions. A full set of thermodynamic data for Eu, Am, and Cm extraction by TODGA from 3.0 M HNO3 is reported. These data are compared to previous extraction results from a 1.0 M HNO3 aqueous medium, and a short discussion of the mixed HEH[EHP]/TODGA system results is offered.

  5. Phase transition in finite systems

    International Nuclear Information System (INIS)

    Chomaz, Ph.; Duflot, V.; Duflot, V.; Gulminelli, F.

    2000-01-01

    The general problem of the definition of a phase transition without employing the thermodynamical limit is addressed. Different necessary conditions are considered and illustrated with examples from different nuclear and general physics phenomenologies. (authors)

  6. Phase transition in finite systems

    Energy Technology Data Exchange (ETDEWEB)

    Chomaz, Ph.; Duflot, V. [Grand Accelerateur National d' Ions Lourds (GANIL), 14 - Caen (France); Duflot, V.; Gulminelli, F. [Laboratoire de Physique Corpusculaire, LPC-ISMRa, CNRS-IN2P3, 14 - Caen (France)

    2000-07-01

    The general problem of the definition of a phase transition without employing the thermodynamical limit is addressed. Different necessary conditions are considered and illustrated with examples from different nuclear and general physics phenomenologies. (authors)

  7. Kilowatt isotope power system. Phase II plan. Volume I. Phase II program plan

    International Nuclear Information System (INIS)

    1978-01-01

    The development of a Kilowatt Isotope Power System (KIPS) was begun in 1975 for the purpose of satisfying the power requirements of satellites in the 1980's. The KIPS is a 238 PuO 2 -fueled organic Rankine cycle turbine power system to provide a design output of 500 to 2000 W. Phase II of the overall 3-phase KIPS program is described. This volume presents a program plan for qualifying the organic Rankine power system for flight test in 1982. The program plan calls for the design and fabrication of the proposed flight power system; conducting a development and a qualification program including both environmental and endurance testing, using an electrical and a radioisotope heat source; planning for flight test and spacecraft integration; and continuing ground demonstration system testing to act as a flight system breadboard and to accumulate life data

  8. Effect of menstrual cycle phase on glucose kinetics in healthy women & women with premenstrual symptoms.

    Directory of Open Access Journals (Sweden)

    Meena K. Nandimath

    2015-11-01

    Full Text Available Objective: To compare the blood glucose levels during the two phases of the menstrual cycle between healthy women and patients with premenstrual syndrome (PMS.Methods: From January of 2012 to the August of 2013, a descriptive cross-sectional study was performed among staff of tertiary care hospital.Inclusion Criteria: 1100 women aged 18 to 45 years, 2 Regular Menstrual cycle.Exclusion Criteria: 1 Menopause 2 Patient on Oral Contraceptive pills.After approval from IEC and informed consent from the 100 enrolled subjects with either the most severe symptoms of PMS or healthy controls. 2ml of venous blood was collected on fasting condition during the follicular phase (5-11 days of  menstrual cycleand the luteal phase of the cycle (19-28 days menstrual cycle and analyzed the serum concentrations of glucose by using the glucose oxidase method.Results: The statistical analysis was done using student's paired T test. P value less than 0.0001was taken as significant.No significant differences between the demographic data of the control and PMS groups were observed. The mean concentrations of glucose were significantly different during the follicular and luteal phases.

  9. Uterine uptake of iodine-123 metaiodobenzylguanidine during the menstrual phase of uterine cycle

    International Nuclear Information System (INIS)

    Bomanji, J.; Britton, K.E.

    1987-01-01

    Radioiodinated I-123 metaiodobenzylguanidine (MIBG) has been used for diagnostic purposes for detection of apudomas. In this paper normal physiological uptake of I-123 MIBG by the uterus during the menstrual phase of the uterine cycle is reported. It is likely that I-123 MIBG can be used to evaluate some of the problems in this context

  10. Uterine uptake of iodine-123 metaiodobenzylguanidine during the menstrual phase of uterine cycle

    Energy Technology Data Exchange (ETDEWEB)

    Bomanji, J.; Britton, K.E.

    1987-08-01

    Radioiodinated I-123 metaiodobenzylguanidine (MIBG) has been used for diagnostic purposes for detection of apudomas. In this paper normal physiological uptake of I-123 MIBG by the uterus during the menstrual phase of the uterine cycle is reported. It is likely that I-123 MIBG can be used to evaluate some of the problems in this context.

  11. Predictive Duty Cycle Control of Three-Phase Active-Front-End Rectifiers

    DEFF Research Database (Denmark)

    Song, Zhanfeng; Tian, Yanjun; Chen, Wei

    2016-01-01

    This paper proposed an on-line optimizing duty cycle control approach for three-phase active-front-end rectifiers, aiming to obtain the optimal control actions under different operating conditions. Similar to finite control set model predictive control strategy, a cost function previously...

  12. Life cycle and economic efficiency analysis phase II : durable pavement markings.

    Science.gov (United States)

    2011-04-01

    This report details the Phase II analysis of the life cycle and economic efficiency of inlaid tape : and thermoplastic. Waterborne paint was included as a non-durable for comparison purposes : only. In order to find the most economical product for sp...

  13. Resting state alpha frequency is associated with menstrual cycle phase, estradiol and use of oral contraceptives.

    Science.gov (United States)

    Brötzner, Christina P; Klimesch, Wolfgang; Doppelmayr, Michael; Zauner, Andrea; Kerschbaum, Hubert H

    2014-08-19

    Ongoing intrinsic brain activity in resting, but awake humans is dominated by alpha oscillations. In human, individual alpha frequency (IAF) is associated with cognitive performance. Noticeable, performance in cognitive and emotional tasks in women is associated with menstrual cycle phase and sex hormone levels, respectively. In the present study, we correlated frequency of alpha oscillation in resting women with menstrual cycle phase, sex hormone level, or use of oral contraceptives. Electroencephalogram (EEG) was recorded from 57 women (aged 24.07 ± 3.67 years) having a natural menstrual cycle as well as from 57 women (aged 22.37 ± 2.20 years) using oral contraceptives while they sat in an armchair with eyes closed. Alpha frequency was related to the menstrual cycle phase. Luteal women showed highest and late follicular women showed lowest IAF or center frequency. Furthermore, IAF as well as center frequency correlated negatively with endogenous estradiol level, but did not reveal an association with endogenous progesterone. Women using oral contraceptives showed an alpha frequency similar to women in the early follicular phase. We suggest that endogenous estradiol modulate resting alpha frequency. Copyright © 2014 The Authors. Published by Elsevier B.V. All rights reserved.

  14. Luteal phase of the menstrual cycle increases sweating rate during exercise

    Directory of Open Access Journals (Sweden)

    Garcia A.M.C.

    2006-01-01

    Full Text Available The present study evaluated whether the luteal phase elevation of body temperature would be offset during exercise by increased sweating, when women are normally hydrated. Eleven women performed 60 min of cycling exercise at 60% of their maximal work load at 32ºC and 80% relative air humidity. Each subject participated in two identical experimental sessions: one during the follicular phase (between days 5 and 8 and the other during the luteal phase (between days 22 and 25. Women with serum progesterone >3 ng/mL, in the luteal phase were classified as group 1 (N = 4, whereas the others were classified as group 2 (N = 7. Post-exercise urine volume (213 ± 80 vs 309 ± 113 mL and specific urine gravity (1.008 ± 0.003 vs 1.006 ± 0.002 changed (P < 0.05 during the luteal phase compared to the follicular phase in group 1. No menstrual cycle dependence was observed for these parameters in group 2. Sweat rate was higher (P < 0.05 in the luteal (3.10 ± 0.81 g m-2 min-1 than in the follicular phase (2.80 ± 0.64 g m-2 min-1 only in group 1. During exercise, no differences related to menstrual cycle phases were seen in rectal temperature, heart rate, rate of perceived exertion, mean skin temperature, and pre- and post-exercise body weight. Women exercising in a warm and humid environment with water intake seem to be able to adapt to the luteal phase increase of basal body temperature through reduced urinary volume and increased sweating rate.

  15. Describing phase coexistence in systems with small phases

    International Nuclear Information System (INIS)

    Lovett, R

    2007-01-01

    Clusters of atoms can be studied in molecular beams and by computer simulation; 'liquid drops' provide elementary models for atomic nuclei and for the critical nuclei of nucleation theory. These clusters are often described in thermodynamic terms, but the behaviour of small clusters near a phase boundary is qualitatively different from the behaviour at a first order phase transition in idealized thermodynamics. In the idealized case the density and entropy show mathematically sharp discontinuities when the phase boundary is crossed. In large, but finite, systems, the phase boundaries become regions of state space wherein these properties vary rapidly but continuously. In small clusters with a large surface/volume ratio, however, the positive interfacial free energy makes it unlikely, even in states on phase boundaries, that a cluster will have a heterogeneous structure. What is actually seen in these states is a structure that fluctuates in time between homogeneous structures characteristic of the two sides of the phase boundary. That is, structural fluctuations are observed. Thermodynamics only predicts average properties; statistical mechanics is required to understand these fluctuations. Failure to distinguish thermodynamic properties and characterizations of fluctuations, particularly in the context of first order phase transitions, has led to suggestions that the classical rules for thermodynamic stability are violated in small systems and that classical thermodynamics provides an inconsistent description of these systems. Much of the confusion stems from taking statistical mechanical identifications of thermodynamic properties, explicitly developed for large systems, and applying them uncritically to small systems. There are no inconsistencies if thermodynamic properties are correctly identified and the distinction between thermodynamic properties and fluctuations is made clear

  16. Should breast MRI be performed with adjustment for the phase in patients’ menstrual cycle? Correlation between mammographic density, age, and background enhancement on breast MRI without adjusting for the phase in patients’ menstrual cycle

    International Nuclear Information System (INIS)

    Uematsu, Takayoshi; Kasami, Masako; Watanabe, Junichiro

    2012-01-01

    Purpose: The purpose of this study was to assess the correlation between mammographic density, age, and background enhancement on breast MRI without adjusting for the phase in patients’ menstrual cycle. Material and methods: The background enhancement of bilateral breast MRI and the breast density of mammography in 146 consecutive women without adjusting for the phase in patients’ menstrual cycle were reviewed. The breast density was classified into four categories according to the American College of Radiology the Breast Imaging Reporting and Data System lexicon. The background enhancement was classified into four categories: minimal, mild, moderate, and marked. The correlations of mammographic breast density as well as age with background enhancement on breast MRI were examined. Results: There was a significant correlation between mammographic breast density and background enhancement (p = 0.011). All nine cases with almost completely fat mammographic breast density showed minimal (78%) or mild (12%) background enhancement on breast MRI. There was a significant inverse correlation between age and background enhancement (p < 0.0001). Younger patients with dense breasts were more likely to demonstrate moderate/marked background enhancement. Conclusion: When no adjusting for the phase in patients’ menstrual cycle, a significant correlation was observed between background enhancement and mammographic density. A significant inverse correlation was also observed between age and background enhancement.

  17. The CEBAF fiber optic phase reference system

    International Nuclear Information System (INIS)

    Crawford, K.; Simrock, S.; Hovater, C.; Krycuk, A.

    1995-01-01

    The specified phase stability of the CEBAF RF distribution system is 2.9 degree rms per linac. Stability is achieved through the use of a temperature and pressure regulated coaxial drive line. Purpose of the fiber optic phase reference system is to monitor the relative phase at the beginning and ending of this drive line, between linacs, injector and separator to determine drift due to ambient temperature fluctuations. The system utilizes an Ortel 1310 nm single mode laser driving Sumitumo optical fiber to distribute a reference signal at 1497 MHz. Phase of this reference signal is compared to the 1427 MHz (LO) and the 70 MHz (IF) via a 360 degree phase detector. The detected information is then routed to the CEBAF control system for display with a specified resolution of ±0.2 degree over a 20 degree phase delta

  18. Phase-Modulated Optical Communication Systems

    CERN Document Server

    Ho, Keang-Po

    2005-01-01

    Fiber-optic communication systems have revolutionized our telecommunication infrastructures – currently, almost all telephone land-line, cellular, and internet communications must travel via some form of optical fibers. In these transmission systems, neither the phase nor frequency of the optical signal carries information – only the intensity of the signal is used. To transmit more information in a single optical carrier, the phase of the optical carrier must be explored. As a result, there is renewed interest in phase-modulated optical communications, mainly in direct-detection DPSK signals for long-haul optical communication systems. When optical amplifiers are used to maintain certain signal level among the fiber link, the system is limited by amplifier noises and fiber nonlinearities. Phase-Modulated Optical Communication Systems surveys this newly popular area, covering the following topics: The transmitter and receiver for phase-modulated coherent lightwave systems Method for performance analysis o...

  19. Fuel cycle modelling of open cycle thorium-fuelled nuclear energy systems

    International Nuclear Information System (INIS)

    Ashley, S.F.; Lindley, B.A.; Parks, G.T.; Nuttall, W.J.; Gregg, R.; Hesketh, K.W.; Kannan, U.; Krishnani, P.D.; Singh, B.; Thakur, A.; Cowper, M.; Talamo, A.

    2014-01-01

    Highlights: • We study three open cycle Th–U-fuelled nuclear energy systems. • Comparison of these systems is made to a reference U-fuelled EPR. • Fuel cycle modelling is performed with UK NNL code “ORION”. • U-fuelled system is economically favourable and needs least separative work per kWh. • Th–U-fuelled systems offer negligible waste and proliferation resistance advantages. - Abstract: In this study, we have sought to determine the advantages, disadvantages, and viability of open cycle thorium–uranium-fuelled (Th–U-fuelled) nuclear energy systems. This has been done by assessing three such systems, each of which requires uranium enriched to ∼20% 235 U, in comparison to a reference uranium-fuelled (U-fuelled) system over various performance indicators, spanning material flows, waste composition, economics, and proliferation resistance. The values of these indicators were determined using the UK National Nuclear Laboratory’s fuel cycle modelling code ORION. This code required the results of lattice-physics calculations to model the neutronics of each nuclear energy system, and these were obtained using various nuclear reactor physics codes and burn-up routines. In summary, all three Th–U-fuelled nuclear energy systems required more separative work capacity than the equivalent benchmark U-fuelled system, with larger levelised fuel cycle costs and larger levelised cost of electricity. Although a reduction of ∼6% in the required uranium ore per kWh was seen for one of the Th–U-fuelled systems compared to the reference U-fuelled system, the other two Th–U-fuelled systems required more uranium ore per kWh than the reference. Negligible advantages and disadvantages were observed for the amount and the properties of the spent nuclear fuel (SNF) generated by the systems considered. Two of the Th–U-fuelled systems showed some benefit in terms of proliferation resistance of the SNF generated. Overall, it appears that there is little

  20. RF phase distribution systems at the SLC

    International Nuclear Information System (INIS)

    Jobe, R.K.; Schwarz, H.D.

    1989-04-01

    Modern large linear accelerators require RF distribution systems with minimal phase drifts and errors. Through the use of existing RF coaxial waveguides, and additional installation of phase reference cables and monitoring equipment, stable RF distribution for the SLC has been achieved. This paper discusses the design and performance of SLAC systems, and some design considerations for future colliders. 6 refs., 4 figs

  1. Analysis within the systems development life-cycle

    CERN Document Server

    Rock-Evans, Rosemary

    1987-01-01

    Analysis within the Systems Development Life-Cycle: Book 1, Data Analysis-The Deliverables provides a comprehensive treatment of data analysis within the systems development life-cycle and all the deliverables that need to be collected in analysis. The purpose of deliverables is explained and a number of alternative ways of collecting them are discussed. This book is comprised of five chapters and begins with an overview of what """"analysis"""" actually means, with particular reference to tasks such as hardware planning and software evaluation and where they fit into the overall cycle. The ne

  2. The thorium fuel cycle in water-moderated reactor systems

    International Nuclear Information System (INIS)

    Critoph, E.

    1977-01-01

    Current interest in the thorium cycle, as an alternative to the uranium cycle, for water-moderated reactors is based on two attractive aspects of its use - the extension of uranium resources, and the related lower sensitivity of energy costs to uranium price. While most of the scientific basis required is already available, some engineering demonstrations are needed to provide better economic data for rational decisions. Thorium and uranium cycles are compared with regard to reactor characteristics and technology, fuel-cycle technology, economic parameters, fuel-cycle costs, and system characteristics. There appear to be no major feasibility problems associated with the use of thorium, although development is required in the areas of fuel testing and fuel management. The use of thorium cycles implies recycling the fuel, and the major uncertainties are in the associated costs. Experience in the design and operation of fuel reprocessing and active-fabrication facilities is required to estimate costs to the accuracy needed for adequately defining the range of conditions economically favourable to thorium cycles. In heavy-water reactors (HWRs) thorium cycles having uranium requirements at equilibrium ranging from zero to a quarter of those for the natural-uranium once-through cycle appear feasible. An ''inventory'' of uranium of between 1 and 2Mg/MW(e) is required for the transition to equilibrium. The cycles with the lowest uranium requirements compete with the others only at high uranium prices. Using thorium in light-water reactors, uranium requirements can be reduced by a factor of between two and three from the once-through uranium cycle. The light-water breeder reactor, promising zero uranium requirements at equilibrium, is being developed. Larger uranium inventories are required than for the HWRs. The lead time, from a decision to use thorium to significant impact on uranium utilization (compared to uranium cycle, recycling plutonium), is some two decades

  3. Solar central receiver hybrid power system. Phase I study

    Energy Technology Data Exchange (ETDEWEB)

    None

    1978-11-01

    A management plan is presented for implementation during the Solar Central Receiver Hybrid Power System - Phase I study project. The project plan and the management controls that will be used to assure technically adequate, timely and cost effective performance of the work required to prepare the designated end products are described. Bechtel in-house controls and those to be used in directing the subcontractors are described. Phase I of the project consists of tradeoff studies, parametric analyses, and engineering studies leading to conceptual definition and evaluation of a commercial hybrid power system that has the potential for supplying economically competitive electric power to a utility grid in the 1985-1990 time frame. The scope also includes the preparation of a development plan for the resolution of technical uncertainties and the preparation of plans and a proposal for Phase II of the program. The technical approach will be based on a central receiver solar energy collection scheme which supplies thermal energy to a combined cycle, generating system, consisting of a gas turbine cycle combined with a steam bottoming cycle by means of a heat recovery steam generator.

  4. Comparison between two forms of vaginally administered progesterone for luteal phase support in assisted reproduction cycles.

    Science.gov (United States)

    Geber, Selmo; Moreira, Ana Carolina Ferreira; de Paula, Sálua Oliveira Calil; Sampaio, Marcos

    2007-02-01

    The use of progesterone for luteal phase support has been demonstrated to be beneficial in assisted reproduction cycles using gonadotrophin-releasing hormone analogues (GnRHa). Two micronized progesterone preparations are available for vaginal administration: capsules and gel. The objective of this study was to compare the efficacy of these two forms for luteal phase support in assisted reproduction cycles. A total of 244 couples undergoing IVF/intracytoplasmic sperm injection cycles were included in the study and were randomly allocated (sealed envelopes) into two groups: group 1 (122) received vaginal capsules of 200 mg of micronized progesterone (Utrogestan), 3 times daily, and group 2 (122) received micronized progesterone in gel (Crinone 8%), once daily. Both groups received progesterone for 13 days beginning day 1 after oocyte retrieval, continuing until the pregnancy test was performed and until 12 weeks of pregnancy. Groups were compared by clinical data and assisted reproduction results and had similar ages and causes of infertility. Although the pregnancy rate was higher for those receiving progesterone gel than capsules (44.26 and 36.06% respectively), this difference was not statistically significant. The study showed that vaginal progesterone gel and capsules used for luteal phase support in assisted reproduction cycles with long protocol GnRHa result in similar pregnancy rates.

  5. Specifics of system of external influences on the life cycle of a construction object

    Directory of Open Access Journals (Sweden)

    Aleksanin Aleksander

    2016-01-01

    Full Text Available There is a very important issue today which includes the harmonious and effective development of the system ‘man –environment’. Construction is a branch of material production, which has a significant negative impact on the world around us. It is necessary to plan and operate processes of construction at all stages of the life cycle of a building without exception, to prevent of ecological threats. The article describes the concept of ‘life cycle’ as applied to various fields of knowledge, analyzes existing in the scientific literature division of the life cycle of buildings in the periods, proposes own approach to the division of periods of the life cycle on the basis of resource-saving. The article proposes the creation of a unified organizational system for the effective management of all periods with the constituent phases and formulates the main external influences on the building life cycle.

  6. Specifics of system of external influences on the life cycle of a construction object

    Directory of Open Access Journals (Sweden)

    Aleksanin Aleksander

    2016-01-01

    Full Text Available There is a very important issue today which includes the harmonious and effective development of the system ‘man–environment’. Construction is a branch of material production, which has a significant negative impact on the world around us. It is necessary to plan and operate processes of construction at all stages of the life cycle of a building without exception, to prevent of ecological threats. The article describes the concept of ‘life cycle’ as applied to various fields of knowledge, analyzes existing in the scientific literature division of the life cycle of buildings in the periods, proposes own approach to the division of periods of the life cycle on the basis of resource-saving. The article proposes the creation of a unified organizational system for the effective management of all periods with the constituent phases and formulates the main external influences on the building life cycle.

  7. Automation of analytical systems in power cycles

    International Nuclear Information System (INIS)

    Staub Lukas

    2008-01-01

    'Automation' is a widely used term in instrumentation and is often applied to signal exchange, PLC and SCADA systems. Common use, however, does not necessarily described autonomous operation of analytical devices. We define an automated analytical system as a black box with an input (sample) and an output (measured value). In addition we need dedicated status lines for assessing the validities of the input for our black box and the output for subsequent systems. We will discuss input parameters, automated analytical processes and output parameters. Further considerations will be given to signal exchange and integration into the operating routine of a power plant. Local control loops (chemical dosing) and the automation of sampling systems are not discussed here. (author)

  8. Two-phase flow in refrigeration systems

    CERN Document Server

    Gu, Junjie; Gan, Zhongxue

    2013-01-01

    Two-Phase Flow in Refrigeration Systems presents recent developments from the authors' extensive research programs on two-phase flow in refrigeration systems. This book covers advanced mass and heat transfer and vapor compression refrigeration systems and shows how the performance of an automotive air-conditioning system is affected through results obtained experimentally and theoretically, specifically with consideration of two-phase flow and oil concentration. The book is ideal for university postgraduate students as a textbook, researchers and professors as an academic reference book, and b

  9. Fluctuations in the limit cycle state and the problem of phase chaos

    International Nuclear Information System (INIS)

    Szepfalusy, P.; Tel, T.

    1981-11-01

    Gaussian fluctuations and first order fluctuation corrections to the deterministic solution are investigated in the framework of the generalized Ginzburg-Landau type equation of motion exhibiting a hard mode transition leading a to homogeneous limit cycle state. It is shown that the stationary distribution of the fluctuations around the limit cycle is not of the form of a Ginzburg-Landau functional. The nature of the further instability in the post bifurcational region, resulting in the phase chaos in the deterministic problem, is found to be qualitatively changed by the presence of noise. (author)

  10. Fast in situ X-ray diffraction phase and stress analysis during complete heat treatment cycles of steel

    International Nuclear Information System (INIS)

    Rocha, A. da S.; Hirsch, T.

    2005-01-01

    This paper presents results obtained with a method for time and temperature resolved analysis of changes in phase composition and stresses/residual stresses during complete heat treatment cycles of steel, including quenching. Sample temperatures of up to 930 deg. C could be reached with a specially designed furnace, where fast cooling of the samples was realized by gas quenching. Measurements for phase and stress analysis could be performed with an acquisition rate of at least one value every 3 s. Results concerning residual stress relaxation during heating, and stress/residual stress development during quenching are presented and discussed for AISI E52100 ball bearing steel. The observed stress development during quenching followed the expected transformation behavior with some deviations that could be explained through the effects of surface decarburization. The system developed proved to be a suitable tool for characterizing phase and stress changes that occur during heat treatment of steels, as a function of time and temperature

  11. INTEGRATED PYROLYSIS COMBINED CYCLE BIOMASS POWER SYSTEM CONCEPT DEFINITION

    International Nuclear Information System (INIS)

    Sandvig, Eric; Walling, Gary; Brown, Robert C.; Pletka, Ryan; Radlein, Desmond; Johnson, Warren

    2003-01-01

    Advanced power systems based on integrated gasification/combined cycles (IGCC) are often presented as a solution to the present shortcomings of biomass as fuel. Although IGCC has been technically demonstrated at full scale, it has not been adopted for commercial power generation. Part of the reason for this situation is the continuing low price for coal. However, another significant barrier to IGCC is the high level of integration of this technology: the gas output from the gasifier must be perfectly matched to the energy demand of the gas turbine cycle. We are developing an alternative to IGCC for biomass power: the integrated (fast) pyrolysis/ combined cycle (IPCC). In this system solid biomass is converted into liquid rather than gaseous fuel. This liquid fuel, called bio-oil, is a mixture of oxygenated organic compounds and water that serves as fuel for a gas turbine topping cycle. Waste heat from the gas turbine provides thermal energy to the steam turbine bottoming cycle. Advantages of the biomass-fueled IPCC system include: combined cycle efficiency exceeding 37 percent efficiency for a system as small as 7.6 MW e ; absence of high pressure thermal reactors; decoupling of fuel processing and power generation; and opportunities for recovering value-added products from the bio-oil. This report provides a technical overview of the system including pyrolyzer design, fuel clean-up strategies, pyrolysate condenser design, opportunities for recovering pyrolysis byproducts, gas turbine cycle design, and Rankine steam cycle. The report also reviews the potential biomass fuel supply in Iowa, provide and economic analysis, and present a summery of benefits from the proposed system

  12. INTEGRATED PYROLYSIS COMBINED CYCLE BIOMASS POWER SYSTEM CONCEPT DEFINITION

    Energy Technology Data Exchange (ETDEWEB)

    Eric Sandvig; Gary Walling; Robert C. Brown; Ryan Pletka; Desmond Radlein; Warren Johnson

    2003-03-01

    Advanced power systems based on integrated gasification/combined cycles (IGCC) are often presented as a solution to the present shortcomings of biomass as fuel. Although IGCC has been technically demonstrated at full scale, it has not been adopted for commercial power generation. Part of the reason for this situation is the continuing low price for coal. However, another significant barrier to IGCC is the high level of integration of this technology: the gas output from the gasifier must be perfectly matched to the energy demand of the gas turbine cycle. We are developing an alternative to IGCC for biomass power: the integrated (fast) pyrolysis/ combined cycle (IPCC). In this system solid biomass is converted into liquid rather than gaseous fuel. This liquid fuel, called bio-oil, is a mixture of oxygenated organic compounds and water that serves as fuel for a gas turbine topping cycle. Waste heat from the gas turbine provides thermal energy to the steam turbine bottoming cycle. Advantages of the biomass-fueled IPCC system include: combined cycle efficiency exceeding 37 percent efficiency for a system as small as 7.6 MW{sub e}; absence of high pressure thermal reactors; decoupling of fuel processing and power generation; and opportunities for recovering value-added products from the bio-oil. This report provides a technical overview of the system including pyrolyzer design, fuel clean-up strategies, pyrolysate condenser design, opportunities for recovering pyrolysis byproducts, gas turbine cycle design, and Rankine steam cycle. The report also reviews the potential biomass fuel supply in Iowa, provide and economic analysis, and present a summery of benefits from the proposed system.

  13. The models of the life cycle of a computer system

    Directory of Open Access Journals (Sweden)

    Sorina-Carmen Luca

    2006-01-01

    Full Text Available The paper presents a comparative study on the patterns of the life cycle of a computer system. There are analyzed the advantages of each pattern and presented the graphic schemes that point out each stage and step in the evolution of a computer system. In the end the classifications of the methods of projecting the computer systems are discussed.

  14. Phase behavior and phase inversion for dispersant systems

    International Nuclear Information System (INIS)

    Solheim, A.; Brandvik, P.J.

    1991-06-01

    This report describes some preliminary phase behavior studies and phase inversion temperature measurements in seawater, bunker oil and dispersant. The objectives have been to find new ways of characterizing dispersants for dispersing oil spill at sea and, perhaps, to throw new lights on the mechanism of dispersion formation (oil-in-water emulsification). The work has been focussed on the relation to phase behavior and the existence of microemulsion in equilibrium with excess oil and water phases. The dispersing process is also compared to the recommended conditions for emulsion formation. When forming an oil-in-water emulsion in an industrial process, it is recommended to choose an emulsifier which gives a phase inversion temperature (PIT) which is 20 - 60 o C higher than the actual temperature for use. The emulsification process must take place close to the PIT which is the temperature at which the emulsion change from oil-in-water emulsion to water-in-oil emulsion when the system is stirred. This condition corresponds to the temperature where the phase behavior change character. The purpose has been to find out if the composition of the dispersants corresponds to the recommendations for oil-in-water emulsification. The amount of experimental work has been limited. Two kinds of experiments have been carried out. Phase behavior studies have been done for seawater, bunker oil and four different dispersants where one had an optimal composition. The phase behavior was hard to interpret and is not recommended for standard dispersants test. The other experimental technique was PIT-measurements by conductivity measurements versus temperature. 4 figs., 1 tab., 4 refs

  15. Life Cycle Assessment of Electricity Systems

    DEFF Research Database (Denmark)

    Turconi, Roberto

    and discussed. For example, electricity used during the manufacturing of the power plant, reference year and data collection approach (process-chain or input-output analysis) strongly affected the impacts of hydro, wind and solar power. This information needs to be documented, to ensure comparability between......), as the efficiency may vary depending on the operation of the plant within the power system. The choice of LCA approach used to solve multi-functionality for combined heat and power plants strongly influenced how the environmental impact of electricity produced at such plants was estimated. When it is not possible...... on aggregated modelling. The results showed that an increase in wind power causes greater emissions from other power plants in the electricity system (which need to ‘cycle’ – adjust their production – more frequently); however, considering the entire electricity system, increasing wind power penetration reduces...

  16. Fossil fuel combined cycle power system

    Science.gov (United States)

    Labinov, Solomon Davidovich; Armstrong, Timothy Robert; Judkins, Roddie Reagan

    2006-10-10

    A system for converting fuel energy to electricity includes a reformer for converting a higher molecular weight gas into at least one lower molecular weight gas, at least one turbine to produce electricity from expansion of at least one of the lower molecular weight gases, and at least one fuel cell. The system can further include at least one separation device for substantially dividing the lower molecular weight gases into at least two gas streams prior to the electrochemical oxidization step. A nuclear reactor can be used to supply at least a portion of the heat the required for the chemical conversion process.

  17. Life cycle assessment of the end-of-life phase of a residential building.

    Science.gov (United States)

    Vitale, Pierluca; Arena, Noemi; Di Gregorio, Fabrizio; Arena, Umberto

    2017-02-01

    The study investigates the potential environmental impacts related to the end-of-life phase of a residential building, identified in a multifamily dwelling of three levels, constructed in the South of Italy by utilizing conventional materials and up-to-date procedures. An attributional life cycle assessment has been utilised to quantify the contributions of each stage of the end-of-life phase, with a particular attention to the management of the demolition waste. The investigation takes into account the selective demolition, preliminary sorting and collection of main components of the building, together with the processes of sorting, recycling and/or disposal of main fractions of the demolition waste. It quantifies the connections between these on-site and off-site processes as well as the main streams of materials sent to recycling, energy recovery, and final disposal. A sensitivity analysis has been eventually carried out by comparing the overall environmental performances of some alternative scenarios, characterised by different criteria for the demolition of the reference building, management of demolition waste and assessment of avoided burdens of the main recycled materials. The results quantify the advantage of an appropriate technique of selective demolition, which could increase the quality and quantity of residues sent to the treatment of resource recovery and safe disposal. They also highlight the contributions to the positive or negative environmental impact of each stage of the investigated waste management system. The recycling of reinforcing steel appears to play a paramount role, accounting for 65% of the total avoided impacts related to respiratory inorganics, 89% of those for global warming and 73% of those for mineral extraction. Copyright © 2016 Elsevier Ltd. All rights reserved.

  18. The thorium fuel cycle in water-moderated reactor systems

    International Nuclear Information System (INIS)

    Critoph, E.

    1977-05-01

    Thorium and uranium cycles are compared with regard to reactor characteristics and technology, fuel-cycle technology, economic parameters, fuel-cycle costs, and system characteristics. In heavy-water reactors (HWRs) thorium cycles having uranium requirements at equilibrium ranging from zero to a quarter of those for the natural-uranium once-through cycle appear feasible. An 'inventory' of uranium of between 1 and 2 Mg/MW(e) is required for the transition to equilibrium. The cycles with the lowest uranium requirements compete with the others only at high uranium prices. Using thorium in light-water reactors, uranium requirements can be reduced by a factor of between two and three from the once-through uranium cycle. The light-water breeder reactor, promising zero uranium requirements at equilibrium, is being developed. Larger uranium inventories are required than for the HWRs. The lead time, from a decision to use thorium to significant impact on uranium utilization (compared to uranium cycle, recycling plutonium) is some two decades

  19. Thermal analysis of a Phase Change Material for a Solar Organic Rankine Cycle

    Science.gov (United States)

    Iasiello, M.; Braimakis, K.; Andreozzi, A.; Karellas, S.

    2017-11-01

    Organic Rankine Cycle (ORC) is a promising technology for low temperature power generation, for example for the utilization of medium temperature solar energy. Since heat generated from solar source is variable throughout the day, the implementation of Thermal Energy Storage (TES) systems to guarantee the continuous operation of solar ORCs is a critical task, and Phase Change Materials (PCM) rely on latent heat to store large amounts of energy. In the present study, a thermal analysis of a PCM for a solar ORC is carried out. Three different types of PCMs are analyzed. The energy equation for the PCM is modeled by using the heat capacity method, and it is solved by employing a 1Dexplicit finite difference scheme. The solar source is modeled with a time-variable temperature boundary condition, with experimental data taken from the literature for two different solar collectors. Results are presented in terms of temperature profiles and stored energy. It has been shown that the stored energy depends on the heat source temperature, on the employed PCM and on the boundary conditions. It has been demonstrated that the use of a metal foam can drastically enhance the stored energy due to the higher overall thermal conductivity.

  20. Phase Noise Compensation for OFDM Systems

    Science.gov (United States)

    Leshem, Amir; Yemini, Michal

    2017-11-01

    We describe a low complexity method for time domain compensation of phase noise in OFDM systems. We extend existing methods in several respects. First we suggest using the Karhunen-Lo\\'{e}ve representation of the phase noise process to estimate the phase noise. We then derive an improved datadirected choice of basis elements for LS phase noise estimation and present its total least square counterpart problem. The proposed method helps overcome one of the major weaknesses of OFDM systems. We also generalize the time domain phase noise compensation to the multiuser MIMO context. Finally we present simulation results using both simulated and measured phased noise. We quantify the tracking performance in the presence of residual carrier offset.

  1. Phase change thermal storage for a solar total energy system

    Science.gov (United States)

    Rice, R. E.; Cohen, B. M.

    1978-01-01

    An analytical and experimental program is being conducted on a one-tenth scale model of a high-temperature (584 K) phase-change thermal energy storage system for installation in a solar total energy test facility at Albuquerque, New Mexico, U.S.A. The thermal storage medium is anhydrous sodium hydroxide with 8% sodium nitrate. The program will produce data on the dynamic response of the system to repeated cycles of charging and discharging simulating those of the test facility. Data will be correlated with a mathematical model which will then be used in the design of the full-scale system.

  2. Single-Cycle Terahertz Pulse Generation from OH1 Crystal via Cherenkov Phase Matching

    Science.gov (United States)

    Uchida, Hirohisa; Oota, Kengo; Okimura, Koutarou; Kawase, Kodo; Takeya, Kei

    2018-06-01

    OH1 crystal is an organic nonlinear optical crystal with a large nonlinear optical constant. However, it has dispersion of refractive indices in the terahertz (THz) frequency. This limits the frequencies that satisfy the phase matching conditions for THz wave generation. In this study, we addressed the phase matching conditions for THz wave generation by combining an OH1 crystal with prism-coupled Cherenkov phase matching. We observed the generation of single-cycle THz pulses with a spectrum covering a frequency range of 3 THz. These results prove that combining prism-coupled Cherenkov phase matching with nonlinear optical crystals yields a THz wave generation method that is insusceptible to crystal dispersion.

  3. Design of an ejector cycle refrigeration system

    International Nuclear Information System (INIS)

    Grazzini, G.; Milazzo, A.; Paganini, D.

    2012-01-01

    Highlights: ► A design procedure is presented for an ejection refrigeration system. ► Properties of applicable operating fluids are presented and R245fa is selected. ► Real gas properties are used. ► The diffuser is designed with a profile that controls momentum change. ► Fluid friction is accounted for along all main components. - Abstract: A design procedure, based on a one-dimensional simulation, is presented for an ejection refrigeration system. Heat exchangers are included in the calculation, accounting for temperature differences between the fluids and for pressure losses. The ideal gas assumption, which is quite common in the literature concerning ejector systems, is avoided. Furthermore, the supersonic diffuser is designed with a continuous profile, without cylindrical piece, controlling the variation of momentum along the flow path and accounting for friction. At design conditions, this should reduce the irreversibility due to the normal shock. A comparison between different operating fluids is presented and R245fa is selected. The results of the design procedure and the expected performance, in terms of first and second law efficiency, are presented.

  4. Development of System Engineering Technology for Nuclear Fuel Cycle

    International Nuclear Information System (INIS)

    Kim, Hodong; Choi, Iljae

    2013-04-01

    The development of efficient process for spent fuel and establishment of system engineering technology to demonstrate the process are required to develop nuclear energy continuously. The demonstration of pyroprocess technology which is proliferation resistance nuclear fuel cycle technology can reduce spent fuel and recycle effectively. Through this, people's trust and support on nuclear power would be obtained. Deriving the optimum nuclear fuel cycle alternative would contribute to establish a policy on back-end nuclear fuel cycle in the future, and developing the nuclear transparency-related technology would contribute to establish amendments of the ROK-U. S. Atomic Energy Agreement scheduled in 2014

  5. Engine cycle design considerations for nuclear thermal propulsion systems

    International Nuclear Information System (INIS)

    Pelaccio, D.G.; Scheil, C.M.; Collins, J.T.

    1993-01-01

    A top-level study was performed which addresses nuclear thermal propulsion system engine cycle options and their applicability to support future Space Exploration Initiative manned lunar and Mars missions. Technical and development issues associated with expander, gas generator, and bleed cycle near-term, solid core nuclear thermal propulsion engines are identified and examined. In addition to performance and weight the influence of the engine cycle type on key design selection parameters such as design complexity, reliability, development time, and cost are discussed. Representative engine designs are presented and compared. Their applicability and performance impact on typical near-term lunar and Mars missions are shown

  6. Development of multilateral comparative evaluation method for fuel cycle system

    International Nuclear Information System (INIS)

    Tamaki, Hitoshi; Ikushima, Takeshi; Nomura, Yasushi; Nakajima, Kiyoshi.

    1998-03-01

    In the near future, Japanese nuclear fuel cycle system will be promoted by national nuclear energy policy, and it''s options i.e. once through, thermal cycle and fast breeder cycle must be selected by multilateral comparative evaluation method from various aspects of safety, society, economy, and e.t.c. Therefore such a problem can be recognized as a social problem of decision making and applied for AHP (Analytic Hierarchy Process) that can multilaterally and comparatively evaluate the problem. On comparative evaluation, much information are needed for decision making, therefore two kinds of databases having these information have been constructed. And then, the multilateral comparative evaluation method consisting of two kinds of databases and AHP for optimum selection of fuel cycle system option have been developed. (author)

  7. HPT Clearance Control: Intelligent Engine Systems-Phase 1

    Science.gov (United States)

    2005-01-01

    The following work has been completed to satisfy the Phase I Deliverables for the "HPT Clearance Control" project under NASA GRC's "Intelligent Engine Systems" program: (1) Need for the development of an advanced HPT ACC system has been very clearly laid out, (2) Several existing and potential clearance control systems have been reviewed, (3) A scorecard has been developed to document the system, performance (fuel burn, range, payload, etc.), thermal, and mechanical characteristics of the existing clearance control systems, (4) Engine size and flight cycle selection for the advanced HPT ACC system has been reviewed with "large engine"/"long range mission" combination showing the most benefit, (5) A scoring criteria has been developed to tie together performance parameters for an objective, data driven comparison of competing systems, and (6) The existing HPT ACC systems have been scored based on this scoring system.

  8. Enhanced response to ozone exposure during the follicular phase of the menstrual cycle

    Energy Technology Data Exchange (ETDEWEB)

    Fox, S.D.; Adams, W.C.; Brookes, K.A.; Lasley, B.L. (Univ. of Calfornia, Davis (United States))

    1993-08-01

    Exposure to ozone (O[sub 3]), a toxic component of photochemical smog, results in significant airway inflammation, respiratory discomfort, and pulmonary function impairment. These effects can be reduced via pretreatment with anti-inflammatory agents. Progesterone, a gonadal steroid, is known to reduce general inflammation in the uterine endometrium. However, it is not known whether fluctuation in blood levels of progesterone, which are experienced during the normal female menstrual cycle, could alter O[sub 3] inflammatory-induced pulmonary responses. In this study, we tested the hypothesis that young, adult females are more responsive to O[sub 3] inhalation with respect to pulmonary function impairment during their follicular (F) menstrual phase when progesterone levels are lowest that during their mid-luteal (ML) phase when progesterone levels are highest. Nine subjects with normal ovarian function were exposed in random order for 1 hour each to filtered air and to 0.30 ppm O[sub 3] in their F and ML menstrual phases. Ozone responsiveness was measured by percent change in pulmonary function from pre- to postexposure. Significant gas concentration effects (filtered air versus O[sub 3]) were observed for forced vital capacity (FVC), forced expiratory volume in 1 sec (FEV[sub 1]), and forced expiratory flow between 25 and 75% of FVC (FEF[sub 25-75]), showed a significant menstrual phase and gas concentration interaction effect, with larger decrements observed in the F menstrual phase when progesterone concentrations were significantly lower. We conclude that young, adult females appear to be more responsive to acute O[sub 3] exposure during the F phase than during the ML phase of their menstrual cycles. This difference in pulmonary function response could be related to the anti-inflammatory effects of increased progesterone concentrations during the luteal phase.

  9. ARC System fuel cycle analysis capability, REBUS-2

    International Nuclear Information System (INIS)

    Hosteny, R.P.

    1978-10-01

    A detailed description is given of the ARC System fuel cycle modules FCI001, FCC001, FCC002, and FCC003 which form the fuel cycle analysis modules of the ARC System. These modules, in conjunction with certain other modules of the ARC System previously described in documents of this series, form the fuel cycle analysis system called REBUS-2. The physical model upon which the REBUS-2 fuel cycle modules are based and the calculational approach used in solving this model are discussed in detail. The REBUS-2 system either solves for the infinite time (i.e., equilibrium) operating conditions of a fuel recycle system under fixed fuel management conditions, or solves for the operating conditions during each of a series of explicitly specified (i.e., nonequilibrium) sequence of burn cycles. The code has the capability to adjust the fuel enrichment, the burn time, and the control poison requirements in order to satisfy user specified constraints on criticality, discharge fuel burnup, or to give the desired multiplication constant at some specified time during the reactor operation

  10. ARC System fuel cycle analysis capability, REBUS-2

    Energy Technology Data Exchange (ETDEWEB)

    Hosteny, R.P.

    1978-10-01

    A detailed description is given of the ARC System fuel cycle modules FCI001, FCC001, FCC002, and FCC003 which form the fuel cycle analysis modules of the ARC System. These modules, in conjunction with certain other modules of the ARC System previously described in documents of this series, form the fuel cycle analysis system called REBUS-2. The physical model upon which the REBUS-2 fuel cycle modules are based and the calculational approach used in solving this model are discussed in detail. The REBUS-2 system either solves for the infinite time (i.e., equilibrium) operating conditions of a fuel recycle system under fixed fuel management conditions, or solves for the operating conditions during each of a series of explicitly specified (i.e., nonequilibrium) sequence of burn cycles. The code has the capability to adjust the fuel enrichment, the burn time, and the control poison requirements in order to satisfy user specified constraints on criticality, discharge fuel burnup, or to give the desired multiplication constant at some specified time during the reactor operation.

  11. The effects of menstrual cycle phase on physical performance in female soccer players

    Science.gov (United States)

    Julian, Ross; Hecksteden, Anne; Fullagar, Hugh H. K.; Meyer, Tim

    2017-01-01

    Background Female soccer has grown extensively in recent years, however differences in gender-specific physiology have rarely been considered. The female reproductive hormones which rise and fall throughout the menstrual cycle, are known to affect numerous cardiovascular, respiratory, thermoregulatory and metabolic parameters, which in turn, may have implications on exercise physiology and soccer performance. Therefore, the main aim of the present study was to investigate potential effects of menstrual cycle phase on performance in soccer specific tests. Methods Nine sub elite female soccer players, all of whom have menstrual cycles of physiological length; performed a series of physical performance tests (Yo-Yo Intermittent endurance test (Yo-Yo IET), counter movement jump (CMJ) and 3x30 m sprints). These were conducted at distinct time points during two main phases of the menstrual cycle (early follicular phase (FP) and mid luteal phase (LP)) where hormones contrasted at their greatest magnitude. Results Yo-Yo IET performance was considerably lower during the mid LP (2833±896 m) as compared to the early FP (3288±800 m). A trend towards significance was observed (p = 0.07) and the magnitude based inferences suggested probabilities of 0/61/39 for superiority/equality/inferiority of performance during the mid LP, leading to the inference of a possibly harmful effect. For CMJ (early FP, 20.0±3.9 cm; mid LP 29.6±3.0 cm, p = 0.33) and sprint (early FP, 4.7±0.1 s; mid LP, 4.7±0.1 s, p = 0.96) performances the results were unclear (8/24/68, 48/0/52, respectively). Conclusion The results of this study are in support of a reduction in maximal endurance performance during the mid LP of the menstrual cycle. However, the same effect was not observed for jumping and sprint performance. Therefore, consideration of cycle phase when monitoring a player’s endurance capacity may be worthwhile. PMID:28288203

  12. Market-Based and System-Wide Fuel Cycle Optimization

    Energy Technology Data Exchange (ETDEWEB)

    Wilson, Paul Philip Hood [Univ. of Wisconsin, Madison, WI (United States); Scopatz, Anthony [Univ. of South Carolina, Columbia, SC (United States); Gidden, Matthew [Univ. of Wisconsin, Madison, WI (United States); Carlsen, Robert [Univ. of Wisconsin, Madison, WI (United States); Mouginot, Baptiste [Univ. of Wisconsin, Madison, WI (United States); Flanagan, Robert [Univ. of South Carolina, Columbia, SC (United States)

    2017-06-13

    This work introduces automated optimization into fuel cycle simulations in the Cyclus platform. This includes system-level optimizations, seeking a deployment plan that optimizes the performance over the entire transition, and market-level optimization, seeking an optimal set of material trades at each time step. These concepts were introduced in a way that preserves the flexibility of the Cyclus fuel cycle framework, one of its most important design principles.

  13. Market-Based and System-Wide Fuel Cycle Optimization

    International Nuclear Information System (INIS)

    Wilson, Paul Philip Hood; Scopatz, Anthony; Gidden, Matthew; Carlsen, Robert; Mouginot, Baptiste; Flanagan, Robert

    2017-01-01

    This work introduces automated optimization into fuel cycle simulations in the Cyclus platform. This includes system-level optimizations, seeking a deployment plan that optimizes the performance over the entire transition, and market-level optimization, seeking an optimal set of material trades at each time step. These concepts were introduced in a way that preserves the flexibility of the Cyclus fuel cycle framework, one of its most important design principles.

  14. Chlamydomonas reinhardtii: duration of its cell cycle and phases at growth rates affected by light intensity

    Czech Academy of Sciences Publication Activity Database

    Vítová, Milada; Bišová, Kateřina; Umysová, Dáša; Hlavová, Monika; Kawano, S.; Zachleder, Vilém; Čížková, Mária

    2011-01-01

    Roč. 233, č. 1 (2011), s. 75-86 ISSN 0032-0935 R&D Projects: GA AV ČR IAA500200614; GA ČR GA525/09/0102; GA ČR GA204/09/0111 Institutional research plan: CEZ:AV0Z50200510 Keywords : Cell division timing * Cell cycle phases * Chlamydomonas Subject RIV: EE - Microbiology, Virology Impact factor: 3.000, year: 2011

  15. Impact of menstrual cycle phase on endocrine effects of partial sleep restriction in healthy women.

    Science.gov (United States)

    LeRoux, Amanda; Wright, Lisa; Perrot, Tara; Rusak, Benjamin

    2014-11-01

    There is extensive evidence that sleep restriction alters endocrine function in healthy young men, increasing afternoon cortisol levels and modifying levels of other hormones that regulate metabolism. Recent studies have confirmed these effects in young women, but have not investigated whether menstrual cycle phase influences these responses. The effects on cortisol levels of limiting sleep to 3h for one night were assessed in two groups of women at different points in their menstrual cycles: mid-follicular and mid-luteal. Eighteen healthy, young women, not taking oral contraceptives (age: 21.8±0.53; BMI: 22.5±0.58 [mean±SEM]), were studied. Baseline sleep durations, eating habits and menstrual cycles were monitored. Salivary samples were collected at six times of day (08:00, 08:30, 11:00, 14:00, 17:00, 20:00) during two consecutive days: first after a 10h overnight sleep opportunity (Baseline) and then after a night with a 3h sleep opportunity (Post-sleep restriction). All were awakened at the same time of day. Women in the follicular phase showed a significant decrease (p=0.004) in their cortisol awakening responses (CAR) after sleep restriction and a sustained elevation in afternoon/evening cortisol levels (p=0.008), as has been reported for men. Women in the luteal phase showed neither a depressed CAR, nor an increase in afternoon/evening cortisol levels. Secondary analyses examined the impact of sleep restriction on self-reported hunger and mood. Menstrual cycle phase dramatically altered the cortisol responses of healthy, young women to a single night of sleep restriction, implicating effects of spontaneous changes in endocrine status on adrenal responses to sleep loss. Copyright © 2014 Elsevier Ltd. All rights reserved.

  16. Blue laser phase change recording system

    International Nuclear Information System (INIS)

    Hofmann, Holger; Dambach, S.Soeren; Richter, Hartmut

    2002-01-01

    The migration paths from DVD phase change recording with red laser to the next generation optical disk formats with blue laser and high NA optics are discussed with respect to optical aberration margins and disc capacities. A test system for the evaluation of phase change disks with more than 20 GB capacity is presented and first results of the recording performance are shown

  17. Cycle for innovative nuclear Gen 4. systems=; Cycle des systemes du futur

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    In the framework of the development of nuclear systems of the 4. generation, the preliminary and schematic reprocessing goals are a cleaning of fission products without a priori separation of the different actinides. The objective of the workshop is to exchange information about the potential efficiency of innovative fuel processing treatments in order to evaluate the impact of impurities on the design of the fuel during its re-fabrication and re-introduction inside the reactor, and on the materials and systems. This document gathers the slides of the 18 presentations given at this workshop: 1 - from the PWR fuel to the closed cycle fast spectrum concepts of generation 4 systems (P. Anzieu, F. Carre, Ph. Brossard, M. Delpech); 2 - the double strata scenarios: objectives and characteristics (S. David and F. Varaine); 3 - why a molten salts thorium file (D. Heuer); 4 - the common 'molten salts' research program of the CNRS (D. Heuer, S. Sanchez); 5 - the hydro-metallurgical reprocessing, the knowledge gained and the statuses of the 5. PCRD, synthesis of the OECD works (C. Madic); 6 - pyro-chemistry: Pyropep status (H. Boussier); 7 - technological bolts identified during the Most project of the 5. PCRD (C. Renault, Ch. Le Brun, M. Delpech and C. Garzenne); 8 - the molten salt reactor concept and its reprocessing options, expected efficiencies (L. Mathieu); 9 - methodology of evaluation of pyro-chemical fuel reprocessing schemes (H. Boussier); 10 - molten salt reactor, design-aided tools for the reactor and the reprocessing plant (O. Gastaldi, E. Walle, O. Koberl, D. Lecarpentier); 11 - status of CEA's prospective studies for the front-end of the fuel reprocessing process/dry ways (S. Bourg); 12 - results of activity coefficient measurements in liquid metals (J. Finne, E. Walle, G. Picard, S. Sanchez and O. Conocar); 13 - potentialities of electrolytic separation and liquid-liquid extraction processes (molten salts/molten metal) for the multi

  18. Extracellular matrix-dependent myosin dynamics during G1-S phase cell cycle progression in hepatocytes

    International Nuclear Information System (INIS)

    Bhadriraju, Kiran; Hansen, Linda K.

    2004-01-01

    Cell spreading and proliferation are tightly coupled in anchorage-dependent cells. While adhesion-dependent proliferation signals require an intact actin cytoskeleton, and some of these signals such as ERK activation have been characterized, the role of myosin in spreading and cell cycle progression under different extracellular matrix (ECM) conditions is not known. Studies presented here examine changes in myosin activity in freshly isolated hepatocytes under ECM conditions that promote either proliferation (high fibronectin density) or growth arrest (low fibronectin density). Three different measures were obtained and related to both spreading and cell cycle progression: myosin protein levels and association with cytoskeleton, myosin light chain phosphorylation, and its ATPase activity. During the first 48 h in culture, corresponding with transit through G1 phase, there was a six-fold increase in both myosin protein levels and myosin association with actin cytoskeleton. There was also a steady increase in myosin light chain phosphorylation and ATPase activity with spreading, which did not occur in non-spread, growth-arrested cells on low density of fibronectin. Myosin-inhibiting drugs blocked ERK activation, cyclin D1 expression, and S phase entry. Overexpression of the cell cycle protein cyclin D1 overcame both ECM-dependent and actomyosin-dependent inhibition of DNA synthesis, suggesting that cyclin D1 is a key event downstream of myosin-dependent cell cycle regulation

  19. Thioaptamer Diagnostic System, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — AM Biotechnologies (AM) will develop a diagnostic system in response to SBIR Topic X10.01 Reusable Diagnostic Lab Technology that will simultaneously detect and...

  20. Thioaptamer Diagnostic System, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — AM Biotechnologies (AM) in partnership with Sandia National Laboratories will develop a Thioaptamer Diagnostic System (TDS) in response to Topic X10.01 Reusable...

  1. SOUL System Maturation, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — Busek Co. Inc. proposes to advance the maturity of an innovative Spacecraft on Umbilical Line (SOUL) System suitable for a wide variety of applications of interest...

  2. SOUL System Maturation, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — Busek Co. Inc. proposes to advance the maturity of an innovative Spacecraft on Umbilical Line (SOUL) System suitable for a wide variety of applications of interest...

  3. Structural Nervous System, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — GTL's SNS technology aids in the operation of new or existing structural health monitoring (SHM) systems by integrating data and power pathways into the structure....

  4. Analysis within the systems development life-cycle

    CERN Document Server

    Rock-Evans, Rosemary

    1987-01-01

    Analysis within the Systems Development Life-Cycle: Book 2, Data Analysis-The Methods describes the methods for carrying out data analysis within the systems development life-cycle and demonstrates how the results of fact gathering can be used to produce and verify the analysis deliverables. A number of alternative methods of analysis other than normalization are suggested. Comprised of seven chapters, this book shows the tasks to be carried out in the logical order of progression-preparation, collection, analysis of the existing system (which comprises the tasks of synthesis, verification, an

  5. The Impact of Menstrual Cycle Phase on Economic Choice and Rationality.

    Science.gov (United States)

    Lazzaro, Stephanie C; Rutledge, Robb B; Burghart, Daniel R; Glimcher, Paul W

    2016-01-01

    It is well known that hormones affect both brain and behavior, but less is known about the extent to which hormones affect economic decision-making. Numerous studies demonstrate gender differences in attitudes to risk and loss in financial decision-making, often finding that women are more loss and risk averse than men. It is unclear what drives these effects and whether cyclically varying hormonal differences between men and women contribute to differences in economic preferences. We focus here on how economic rationality and preferences change as a function of menstrual cycle phase in women. We tested adherence to the Generalized Axiom of Revealed Preference (GARP), the standard test of economic rationality. If choices satisfy GARP then there exists a well-behaved utility function that the subject's decisions maximize. We also examined whether risk attitudes and loss aversion change as a function of cycle phase. We found that, despite large fluctuations in hormone levels, women are as technically rational in their choice behavior as their male counterparts at all phases of the menstrual cycle. However, women are more likely to choose risky options that can lead to potential losses while ovulating; during ovulation women are less loss averse than men and therefore more economically rational than men in this regard. These findings may have market-level implications: ovulating women more effectively maximize expected value than do other groups.

  6. Dux4 induces cell cycle arrest at G1 phase through upregulation of p21 expression

    International Nuclear Information System (INIS)

    Xu, Hongliang; Wang, Zhaoxia; Jin, Suqin; Hao, Hongjun; Zheng, Lemin; Zhou, Boda; Zhang, Wei; Lv, He; Yuan, Yun

    2014-01-01

    Highlights: • Dux4 induced TE671 cell proliferation defect and G1 phase arrest. • Dux4 upregulated p21 expression without activating p53. • Silencing p21 rescued Dux4 mediated proliferation defect and cell cycle arrest. • Sp1 binding site was required for Dux4-induced p21 promoter activation. - Abstract: It has been implicated that Dux4 plays crucial roles in development of facioscapulohumeral dystrophy. But the underlying myopathic mechanisms and related down-stream events of this retrogene were far from clear. Here, we reported that overexpression of Dux4 in a cell model TE671 reduced cell proliferation rate, and increased G1 phase accumulation. We also determined the impact of Dux4 on p53/p21 signal pathway, which controls the checkpoint in cell cycle progression. Overexpression of Dux4 increased p21 mRNA and protein level, while expression of p53, phospho-p53 remained unchanged. Silencing p21 rescued Dux4 mediated proliferation defect and cell cycle arrest. Furthermore, we demonstrated that enhanced Dux4 expression increased p21 promoter activity and elevated expression of Sp1 transcription factor. Mutation of Sp1 binding site decreased dux4 induced p21 promoter activation. Chromatin immunoprecipitation (ChIP) assays confirmed the Dux4-induced binding of Sp1 to p21 promoter in vivo. These results suggest that Dux4 might induce proliferation inhibition and G1 phase arrest through upregulation of p21

  7. Effects of sex, menstrual cycle phase, and endogenous hormones on cognition in schizophrenia.

    Science.gov (United States)

    Rubin, Leah H; Carter, C Sue; Drogos, Lauren L; Pournajafi-Nazarloo, Hossein; Sweeney, John A; Maki, Pauline M

    2015-08-01

    In women with schizophrenia, cognition has been shown to be enhanced following administration of hormone therapy or oxytocin. We examined how natural hormonal changes across the menstrual cycle influence cognition in women with schizophrenia. We hypothesized that female patients would perform worse on "female-dominant" tasks (verbal memory/fluency) and better on "male-dominant" tasks (visuospatial) during the early follicular phase (low estradiol and progesterone) compared to midluteal phase (high estradiol and progesterone) in relation to estradiol but not progesterone. Fifty-four women (23 with schizophrenia) completed cognitive assessments and provided blood for sex steroid assays and oxytocin at early follicular (days 2-4) and midluteal (days 20-22) phases. Men were included to verify the expected pattern of sex differences on cognitive tests. Expected sex differences were observed on "female-dominant" and "male-dominant" tasks (pperformance did not change across the menstrual cycle on "female-dominant" or "male-dominant" tasks in either group. Estradiol and progesterone levels were unrelated to cognitive performance. Oxytocin levels did not change across the menstrual cycle but were positively related to performance on "female-dominant" tasks in female patients only (pperformance on female dominant tests in women. Physiological levels of oxytocin may thus have a more powerful benefit in some cognitive domains than estrogens in schizophrenia. Copyright © 2015 Elsevier B.V. All rights reserved.

  8. The Impact of Menstrual Cycle Phase on Economic Choice and Rationality.

    Directory of Open Access Journals (Sweden)

    Stephanie C Lazzaro

    Full Text Available It is well known that hormones affect both brain and behavior, but less is known about the extent to which hormones affect economic decision-making. Numerous studies demonstrate gender differences in attitudes to risk and loss in financial decision-making, often finding that women are more loss and risk averse than men. It is unclear what drives these effects and whether cyclically varying hormonal differences between men and women contribute to differences in economic preferences. We focus here on how economic rationality and preferences change as a function of menstrual cycle phase in women. We tested adherence to the Generalized Axiom of Revealed Preference (GARP, the standard test of economic rationality. If choices satisfy GARP then there exists a well-behaved utility function that the subject's decisions maximize. We also examined whether risk attitudes and loss aversion change as a function of cycle phase. We found that, despite large fluctuations in hormone levels, women are as technically rational in their choice behavior as their male counterparts at all phases of the menstrual cycle. However, women are more likely to choose risky options that can lead to potential losses while ovulating; during ovulation women are less loss averse than men and therefore more economically rational than men in this regard. These findings may have market-level implications: ovulating women more effectively maximize expected value than do other groups.

  9. Dux4 induces cell cycle arrest at G1 phase through upregulation of p21 expression

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Hongliang; Wang, Zhaoxia; Jin, Suqin; Hao, Hongjun [Department of Neurology, Peking University First Hospital, Beijing 100034 (China); Zheng, Lemin [The Institute of Cardiovascular Sciences, Peking University Health Science Center, Key Laboratory of Molecular Cardiovascular Sciences of Education Ministry, Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides of Health Ministry, Beijing 100191 (China); Zhou, Boda [The Department of Cardiology, Peking University Third Hospital, Beijing 100191 (China); Zhang, Wei; Lv, He [Department of Neurology, Peking University First Hospital, Beijing 100034 (China); Yuan, Yun, E-mail: yuanyun2002@sohu.com [Department of Neurology, Peking University First Hospital, Beijing 100034 (China)

    2014-03-28

    Highlights: • Dux4 induced TE671 cell proliferation defect and G1 phase arrest. • Dux4 upregulated p21 expression without activating p53. • Silencing p21 rescued Dux4 mediated proliferation defect and cell cycle arrest. • Sp1 binding site was required for Dux4-induced p21 promoter activation. - Abstract: It has been implicated that Dux4 plays crucial roles in development of facioscapulohumeral dystrophy. But the underlying myopathic mechanisms and related down-stream events of this retrogene were far from clear. Here, we reported that overexpression of Dux4 in a cell model TE671 reduced cell proliferation rate, and increased G1 phase accumulation. We also determined the impact of Dux4 on p53/p21 signal pathway, which controls the checkpoint in cell cycle progression. Overexpression of Dux4 increased p21 mRNA and protein level, while expression of p53, phospho-p53 remained unchanged. Silencing p21 rescued Dux4 mediated proliferation defect and cell cycle arrest. Furthermore, we demonstrated that enhanced Dux4 expression increased p21 promoter activity and elevated expression of Sp1 transcription factor. Mutation of Sp1 binding site decreased dux4 induced p21 promoter activation. Chromatin immunoprecipitation (ChIP) assays confirmed the Dux4-induced binding of Sp1 to p21 promoter in vivo. These results suggest that Dux4 might induce proliferation inhibition and G1 phase arrest through upregulation of p21.

  10. Phase locking and multiple oscillating attractors for the coupled mammalian clock and cell cycle.

    Science.gov (United States)

    Feillet, Céline; Krusche, Peter; Tamanini, Filippo; Janssens, Roel C; Downey, Mike J; Martin, Patrick; Teboul, Michèle; Saito, Shoko; Lévi, Francis A; Bretschneider, Till; van der Horst, Gijsbertus T J; Delaunay, Franck; Rand, David A

    2014-07-08

    Daily synchronous rhythms of cell division at the tissue or organism level are observed in many species and suggest that the circadian clock and cell cycle oscillators are coupled. For mammals, despite known mechanistic interactions, the effect of such coupling on clock and cell cycle progression, and hence its biological relevance, is not understood. In particular, we do not know how the temporal organization of cell division at the single-cell level produces this daily rhythm at the tissue level. Here we use multispectral imaging of single live cells, computational methods, and mathematical modeling to address this question in proliferating mouse fibroblasts. We show that in unsynchronized cells the cell cycle and circadian clock robustly phase lock each other in a 1:1 fashion so that in an expanding cell population the two oscillators oscillate in a synchronized way with a common frequency. Dexamethasone-induced synchronization reveals additional clock states. As well as the low-period phase-locked state there are distinct coexisting states with a significantly higher period clock. Cells transition to these states after dexamethasone synchronization. The temporal coordination of cell division by phase locking to the clock at a single-cell level has significant implications because disordered circadian function is increasingly being linked to the pathogenesis of many diseases, including cancer.

  11. Guidance for the application of an assessment methodology for innovative nuclear energy systems. INPRO manual - Environment. Vol. 7 of the final report of phase 1 of the International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO)

    International Nuclear Information System (INIS)

    2008-11-01

    The International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO) was initiated in the year 2000, based on a resolution of the IAEA General Conference (GC(44)/RES/21). The main objectives of INPRO are (1) to help to ensure that nuclear energy is available to contribute in fulfilling energy needs in the 21st century in a sustainable manner, (2) to bring together both technology holders and technology users to consider jointly the international and national actions required to achieve desired innovations in nuclear reactors and fuel cycles; and (3) to create a forum to involve all relevant stakeholders that will have an impact on, draw from, and complement the activities of existing institutions, as well as ongoing initiatives at the national and international level. The INPRO manual is comprised of an overview volume (No. 1), and eight additional volumes covering the areas of economics (Volume 2), infrastructure (Volume 3), waste management (Volume 4), proliferation resistance (Volume 5), physical protection (Volume 6), environment (laid out in this volume) (Volume 7), safety of nuclear reactors (Volume 8), and safety of nuclear fuel cycle facilities (Volume 9). This volume should provide guidance to the assessor of an INS that is planned (or maintained or enlarged), describing how to apply the INPRO methodology in the area of environment. It follows the guidelines of the INPRO report 'Methodology for the assessment of innovative nuclear reactors and fuel cycles', together with its previous report 'Guidance for the evaluation for innovative nuclear reactors and fuel cycles'. The INPRO Manual starts with an introduction in Chapter 1. In Chapter 2 an overview is presented what kind of information must be available to an INPRO assessor to perform his environmental assessment. In Chapter 3 the background of the INPRO environmental basic principle BP1, the corresponding user requirements (UR) and criteria (CR) consisting of indicators (IN) and acceptance

  12. Potassium cycling and losses in grassland systems : a review

    NARCIS (Netherlands)

    Kayser, M; Isselstein, J

    Cycling of potassium in grassland systems has received relatively little attention in research and practice in recent years. Balanced nutrient systems require consideration of nutrients other than nitrogen (N). Potassium (K) is needed in large amounts and is closely related to N nutrition. In

  13. INFLUENCE OF EMBRYO IMPLANTATION ON ENDOMETRIUM IN LUTEAL PHASE OF MENSTRUAL CYCLE

    Directory of Open Access Journals (Sweden)

    Romana Dmitrović

    2018-02-01

    Full Text Available Background: Based on the facts known from embryology, rapid endometrial growth during late luteal phase of the cycle could be expected. In this research, we sought to establish if normal intrauterine pregnancy could be confirmed before gestational sac vizualization, by trans- vaginal ultrasound and hormonal tests. The primary hypothesis was that the endometrial thickness and/or volume in the luteal phase of the cycle, in cycles resulting in normal intra- uterine pregnancy, is significantly different compared to non-conception cycles. We also hypothesized that endometrial thickness and/or volume are different in cycles resulting in normal intrauterine pregnancy compared to cycles resulting in abnormal pregnancy, namely biochemical and ectopic pregnancy, and spontaneous abortion. Additionally, next to endometrial volumes, we decided to measure the endometrium in three planes (thick- ness, length and width, to see if the hypothesized endometrial volume differences could be approximated by this simple surrogate technique, which is available in most parts of the world. Methods: This was a prospective observational study of women enrolled in an assisted reproduction program. Patients were stimulated with standard stimulation protocols. The oocyte retrieval was performed 36 hours after the hCG administration and the embryo was transferred 3 or 5 days later. Patients were first seen on day 20–24 of the cycle , and then on day 27–30 of the cycle. A blood sample was taken, and 3D transvaginal ultrasound was done. Following the completion of study visits, patients with a positive HCG test received phone call check- ups until week 12 of pregnancy, and were stratified according to pregnancy outcome. Results: 80 subjects signed the informed consent form. 4 patients had the IUI in the stimulated cycle, one had ET in spontaneous cycle, and 74 patients had undergone IVF/ET in the stimulated cycle. 63 patients in the stimulated cycles completed the study and

  14. Removal of Direct Current Link Harmonic Ripple in Single Phase Voltage Source Inverter Systems Using Supercapacitors

    Science.gov (United States)

    2016-09-01

    Khaligh, “Optimization of sizing and battery cycle life in battery/ultracapacitor hybrid energy storage systems for electric vehicle applications...depth cycling operation in photovoltaic system ,” in 22nd International Conference “Mixed Design of Integrated Circuits and Systems ,” Toruń, Poland...CURRENT LINK HARMONIC RIPPLE IN SINGLE-PHASE VOLTAGE SOURCE INVERTER SYSTEMS USING SUPERCAPACITORS by Gabriel D. Hernandez September 2016

  15. Electronic construction collaboration system : phase III.

    Science.gov (United States)

    2011-12-01

    This phase of the electronic collaboration project involved two major efforts: 1) implementation of AEC Sync (formerly known as Attolist), a web-based project management system (WPMS), on the Broadway Viaduct Bridge Project and the Iowa Falls Arch Br...

  16. Tactile Data Entry System, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — Building on our successful Phase I Tactile Data Entry program, Barron Associates proposes development of a Glove-Enabled Computer Operations (GECO) system to permit...

  17. LIFE CYCLE ASSESSMENT IN HEALTHCARE SYSTEM OPTIMIZATION. INTRODUCTION

    Directory of Open Access Journals (Sweden)

    V. Sarancha

    2015-03-01

    Full Text Available Article describes the life cycle assessment method and introduces opportunities for method performance in healthcare system settings. LSA draws attention to careful use of resources, environmental, human and social responsibility. Modelling of environmental and technological inputs allows optimizing performance of the system. Various factors and parameters that may influence effectiveness of different sectors in healthcare system are detected. Performance optimization of detected parameters could lead to better system functioning, higher patient safety, economic sustainability and reduce resources consumption.

  18. New method of thermal cycling stability test of phase change material

    Directory of Open Access Journals (Sweden)

    Putra Nandy

    2017-01-01

    Full Text Available Phase Change Material (PCM is the most promising material as thermal energy storage nowadays. As thermal energy storage, examination on endurance of material for long-term use is necessary to be carried out. Therefore, thermal cycling test is performed to ensure thermal stability of PCM. This study have found a new method on thermal cycling test of PCM sample by using thermoelectric as heating and cooling element. RT 22 HC was used as PCM sample on this thermal cycling test. The new method had many advantages compared to some references of the same test. It just needed a small container for PCM sample. The thermoelectric could release heat to PCM sample and absorb heat from PCM sample uniformly, respectively, was called as heating and cooling process. Hence, thermoelectric had to be supported by a relay control device to change its polarity so it could heat and cool PCM sample alternately and automatically. On the other hand, the thermoelectric was cheap, easy to be found and available in markets. It can be concluded that new method of thermal cycling test by using thermoelectric as source of heating and cooling can be a new reference for performing thermal cycling test on PCM.

  19. Hospital System Readmissions: A Care Cycle Approach

    Directory of Open Access Journals (Sweden)

    Cody Mullen

    2012-01-01

    Full Text Available Hospital readmission rates can be used as an indicator of the quality of health care services and can highlight high-priority research areas to ensure better health. A readmission is defined as when a patient is discharged from an acute care hospital and is admitted back to an acute care hospital in a set amount of days, with 30 days being the current national standard. On average, 19.6% of Medicare patients are readmitted to the hospital within 30 days of discharge and 56.1% within a year (Jencks, Williams, & Coleman, 2009. The hypothesis of this study was that the discharge location, or where a patient went immediately after discharge, would not have a significant effect on readmissions. A data set with all admission records was obtained from a major health provider. These data contain all hospital patients’ demographic and diagnosis information. General, women’s, and children’s hospitals were looked at from a system perspective to study the discharge location of patients as well as the effects of patient demographics on discharge location. By using a z-significance test in Microsoft Excel and SAS 9.2, it was discovered that patients discharged to home have a significantly lower likelihood of readmission. Generally, patients who are discharged to an extended care or intermediate care facility or patients with home health carerelated services had a significantly higher likelihood of being readmitted. The findings may indicate a possible need for an institution-to-institution intervention as well as institution-to-patient intervention. Future work will develop potential interventions in partnership with hospital staff.

  20. Geometric phases in discrete dynamical systems

    Energy Technology Data Exchange (ETDEWEB)

    Cartwright, Julyan H.E., E-mail: julyan.cartwright@csic.es [Instituto Andaluz de Ciencias de la Tierra, CSIC–Universidad de Granada, E-18100 Armilla, Granada (Spain); Instituto Carlos I de Física Teórica y Computacional, Universidad de Granada, E-18071 Granada (Spain); Piro, Nicolas, E-mail: nicolas.piro@epfl.ch [École Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne (Switzerland); Piro, Oreste, E-mail: piro@imedea.uib-csic.es [Departamento de Física, Universitat de les Illes Balears, E-07122 Palma de Mallorca (Spain); Tuval, Idan, E-mail: ituval@imedea.uib-csic.es [Mediterranean Institute for Advanced Studies, CSIC–Universitat de les Illes Balears, E-07190 Mallorca (Spain)

    2016-10-14

    In order to study the behaviour of discrete dynamical systems under adiabatic cyclic variations of their parameters, we consider discrete versions of adiabatically-rotated rotators. Parallelling the studies in continuous systems, we generalize the concept of geometric phase to discrete dynamics and investigate its presence in these rotators. For the rotated sine circle map, we demonstrate an analytical relationship between the geometric phase and the rotation number of the system. For the discrete version of the rotated rotator considered by Berry, the rotated standard map, we further explore this connection as well as the role of the geometric phase at the onset of chaos. Further into the chaotic regime, we show that the geometric phase is also related to the diffusive behaviour of the dynamical variables and the Lyapunov exponent. - Highlights: • We extend the concept of geometric phase to maps. • For the rotated sine circle map, we demonstrate an analytical relationship between the geometric phase and the rotation number. • For the rotated standard map, we explore the role of the geometric phase at the onset of chaos. • We show that the geometric phase is related to the diffusive behaviour of the dynamical variables and the Lyapunov exponent.

  1. Entransy in phase-change systems

    CERN Document Server

    Gu, Junjie

    2014-01-01

    Entransy in Phase-Change Systems summarizes recent developments in the area of entransy, especially on phase-change processes. This book covers new developments in the area including the great potential for energy saving for process industries, decreasing carbon dioxide emissions, reducing energy bills and improving overall efficiency of systems. This concise volume is an ideal book for engineers and scientists in energy-related industries.

  2. Proterozoic Milankovitch cycles and the history of the solar system.

    Science.gov (United States)

    Meyers, Stephen R; Malinverno, Alberto

    2018-06-19

    The geologic record of Milankovitch climate cycles provides a rich conceptual and temporal framework for evaluating Earth system evolution, bestowing a sharp lens through which to view our planet's history. However, the utility of these cycles for constraining the early Earth system is hindered by seemingly insurmountable uncertainties in our knowledge of solar system behavior (including Earth-Moon history), and poor temporal control for validation of cycle periods (e.g., from radioisotopic dates). Here we address these problems using a Bayesian inversion approach to quantitatively link astronomical theory with geologic observation, allowing a reconstruction of Proterozoic astronomical cycles, fundamental frequencies of the solar system, the precession constant, and the underlying geologic timescale, directly from stratigraphic data. Application of the approach to 1.4-billion-year-old rhythmites indicates a precession constant of 85.79 ± 2.72 arcsec/year (2σ), an Earth-Moon distance of 340,900 ± 2,600 km (2σ), and length of day of 18.68 ± 0.25 hours (2σ), with dominant climatic precession cycles of ∼14 ky and eccentricity cycles of ∼131 ky. The results confirm reduced tidal dissipation in the Proterozoic. A complementary analysis of Eocene rhythmites (∼55 Ma) illustrates how the approach offers a means to map out ancient solar system behavior and Earth-Moon history using the geologic archive. The method also provides robust quantitative uncertainties on the eccentricity and climatic precession periods, and derived astronomical timescales. As a consequence, the temporal resolution of ancient Earth system processes is enhanced, and our knowledge of early solar system dynamics is greatly improved.

  3. Phase diagram of strongly correlated Fermi systems

    International Nuclear Information System (INIS)

    Zverev, M.V.; Khodel', V.A.; Baldo, M.

    2000-01-01

    Phase transitions in uniform Fermi systems with repulsive forces between the particles caused by restructuring of quasiparticle filling n(p) are analyzed. It is found that in terms of variables, i.e. density ρ, nondimensional binding constant η, phase diagram of a strongly correlated Fermi system for rather a wide class of interactions reminds of a puff-pastry pie. Its upper part is filled with fermion condensate, the lower one - with normal Fermi-liquid. They are separated by a narrow interlayer - the Lifshits phase, characterized by the Fermi multibound surface [ru

  4. Guidance for the application of an assessment methodology for innovative nuclear energy systems. INPRO manual - Proliferation resistance. Vol. 5 of the final report of phase 1 of the International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO)

    International Nuclear Information System (INIS)

    2008-11-01

    The International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO) was initiated in the year 2000, based on a resolution of the IAEA General Conference (GC(44)/RES/21). The main objectives of INPRO are (1) to help to ensure that nuclear energy is available to contribute in fulfilling energy needs in the 21st century in a sustainable manner, (2) to bring together both technology holders and technology users to consider jointly the international and national actions required to achieve desired innovations in nuclear reactors and fuel cycles; and (3) to create a forum to involve all relevant stakeholders that will have an impact on, draw from, and complement the activities of existing institutions, as well as ongoing initiatives at the national and international level. The INPRO manual is comprised of an overview volume (No. 1), and eight additional volumes covering the areas of economics (Volume 2), infrastructure (Volume 3), waste management (Volume 4), proliferation resistance (laid out in this report) (Volume 5), physical protection (Volume 6), environment (Volume 7), safety of nuclear reactors (Volume 8), and safety of nuclear fuel cycle facilities (Volume 9). This volume of the INPRO manual is based on the results of an INPRO study on proliferation resistance of the DUPIC fuel cycle performed by the Republic of Korea during 2005 and 2006, recommendations from IAEA consultancy meetings, and on a special service agreement with G. Pshakin (Russian Federation). The INPRO Manual starts with an introduction in Chapter 1. In Chapter 2, the necessary information is described to perform an INPRO assessment in the area of proliferation resistance. Explanatory notes on the INPRO basic principles (BP) and user requirements (UR) in the area of proliferation resistance, are reproduced in Chapter 3 to provide context for the assessor; additionally, background of each criterion (CR) and a corresponding procedure is described how to perform an INPRO assessment. The

  5. Guidance for the application of an assessment methodology for Innovative Nuclear Energy Systems. INPRO manual - Economics. Vol. 2 of the final report of phase 1 of the International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO)

    International Nuclear Information System (INIS)

    2008-11-01

    The International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO) was initiated in the year 2000, based on a resolution of the IAEA General Conference (GC(44)/RES/21). The main objectives of INPRO are (1) to help to ensure that nuclear energy is available to contribute in fulfilling energy needs in the 21st century in a sustainable manner, (2) to bring together both technology holders and technology users to consider jointly the international and national actions required to achieve desired innovations in nuclear reactors and fuel cycles; and (3) to create a forum to involve all relevant stakeholders that will have an impact on, draw from, and complement the activities of existing institutions, as well as ongoing initiatives at the national and international level. This publication elaborates on the guidance given in the INPRO report 'Methodology for the assessment of innovative nuclear reactors and fuel cycles', IAEA-TECDOC-1434 (2004), and the previous INPRO report 'Guidance for the evaluation for innovative nuclear reactors and fuel cycles', IAEA-TECDOC-1362 (2003) in the area of economics. The information presented in Volume 1 of the INPRO manual should be considered to be an integral part of this volume and the user should be familiar with that information. The goal of the INPRO Manual for the area of economics (Volume 2) is to provide guidance for performing an INPRO assessment, as described in Volume 1 of the INPRO manual, in the area of economics. The manual is not intended to provide guidance on how to design an INS to meet the INPRO requirements in the area of economics: rather, the focus is on the assessment method and the evaluation of the INPRO criteria in the area of economics. The INPRO assessor, i.e. the individual or group of individuals carrying out the assessment, is assumed to be knowledgeable in the area of economics and financial analysis. The INPRO assessment will either confirm that the INPRO economic criteria are fulfilled

  6. Guidance for the application of an assessment methodology for innovative nuclear energy systems. INPRO manual - Waste management. Vol. 4 of the final report of phase 1 of the International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO)

    International Nuclear Information System (INIS)

    2008-11-01

    The International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO) was initiated in the year 2000, based on a resolution of the IAEA General Conference (GC(44)/RES/21). The main objectives of INPRO are (1) to help to ensure that nuclear energy is available to contribute in fulfilling energy needs in the 21st century in a sustainable manner, (2) to bring together both technology holders and technology users to consider jointly the international and national actions required to achieve desired innovations in nuclear reactors and fuel cycles; and (3) to create a forum to involve all relevant stakeholders that will have an impact on, draw from, and complement the activities of existing institutions, as well as ongoing initiatives at the national and international level. The INPRO manual is comprised of an overview volume (No. 1), and eight additional volumes covering the areas of economics (Volume 2), infrastructure (Volume 3), waste management (Volume 4), proliferation resistance (laid out in this report) (Volume 5), physical protection (Volume 6), environment (Volume 7), safety of nuclear reactors (Volume 8), and safety of nuclear fuel cycle facilities (Volume 9). This volume of the INPRO manual is based on the results of an INPRO study on proliferation resistance of the DUPIC fuel cycle performed by the Republic of Korea during 2005 and 2006, recommendations from IAEA consultancy meetings, and on a special service agreement with G. Pshakin (Russian Federation). The INPRO Manual starts with an introduction in Chapter 1. In Chapter 2, the necessary information is described to perform an INPRO assessment in the area of proliferation resistance. Explanatory notes on the INPRO basic principles (BP) and user requirements (UR) in the area of proliferation resistance, are reproduced in Chapter 3 to provide context for the assessor; additionally, background of each criterion (CR) and a corresponding procedure is described how to perform an INPRO assessment. The

  7. Lunar Phase Modulates Circadian Gene Expression Cycles in the Broadcast Spawning Coral Acropora millepora.

    Science.gov (United States)

    Brady, Aisling K; Willis, Bette L; Harder, Lawrence D; Vize, Peter D

    2016-04-01

    Many broadcast spawning corals in multiple reef regions release their gametes with incredible temporal precision just once per year, using the lunar cycle to set the night of spawning. Moonlight, rather than tides or other lunar-regulated processes, is thought to be the proximate factor responsible for linking the night of spawning to the phase of the Moon. We compared patterns of gene expression among colonies of the broadcast spawning coral Acropora millepora at different phases of the lunar cycle, and when they were maintained under one of three experimentally simulated lunar lighting treatments: i) lunar lighting conditions matching those on the reef, or lunar patterns mimicking either ii) constant full Moon conditions, or iii) constant new Moon conditions. Normal lunar illumination was found to shift both the level and timing of clock gene transcription cycles between new and full moons, with the peak hour of expression for a number of genes occurring earlier in the evening under a new Moon when compared to a full Moon. When the normal lunar cycle is replaced with nighttime patterns equivalent to either a full Moon or a new Moon every evening, the normal monthlong changes in the level of expression are destroyed for most genes. In combination, these results indicate that daily changes in moonlight that occur over the lunar cycle are essential for maintaining normal lunar periodicity of clock gene transcription, and this may play a role in regulating spawn timing. These data also show that low levels of light pollution may have an impact on coral biological clocks. © 2016 Marine Biological Laboratory.

  8. Analysis within the systems development life-cycle

    CERN Document Server

    Rock-Evans, Rosemary

    1987-01-01

    Analysis within the Systems Development Life-Cycle, Book 3: Activity Analysis - The Deliverables provides a comprehensive coverage of the deliverables of activity analysis. The book also details purpose of each deliverable in the context of the next tasks in the systems development cycle (SDC). The text first covers the concept of deliverables and the benefits of making deliverables visible. In the second chapter, the book introduces the main concepts and diagrammatic techniques of activity analysis. The third chapter deals with the important classes or categories of concept, while the fourth

  9. Analysis within the systems development life-cycle

    CERN Document Server

    Rock-Evans, Rosemary

    1987-01-01

    Analysis within the Systems Development Life-Cycle: Book 4, Activity Analysis-The Methods describes the techniques and concepts for carrying out activity analysis within the systems development life-cycle. Reference is made to the deliverables of data analysis and more than one method of analysis, each a viable alternative to the other, are discussed. The """"bottom-up"""" and """"top-down"""" methods are highlighted. Comprised of seven chapters, this book illustrates how dependent data and activities are on each other. This point is especially brought home when the task of inventing new busin

  10. Environmental Impacts of Solar Thermal Systems with Life Cycle Assessment

    OpenAIRE

    De Laborderie , Alexis; Puech , Clément; Adra , Nadine; Blanc , Isabelle; Beloin-Saint-Pierre , Didier; Padey , Pierryves; Payet , Jérôme; Sie , Marion; Jacquin , Philippe

    2011-01-01

    Available on: http://www.ep.liu.se/ecp/057/vol14/002/ecp57vol14_002.pdf; International audience; Solar thermal systems are an ecological way of providing domestic hot water. They are experiencing a rapid growth since the beginning of the last decade. This study characterizes the environmental performances of such installations with a life-cycle approach. The methodology is based on the application of the international standards of Life Cycle Assessment. Two types of systems are presented. Fir...

  11. [EEG alpha indices in dependence on the menstrual cycle phase and salivary progesterone].

    Science.gov (United States)

    Bazanova, O M; Kondratenko, A V; Kuz'minova, O I; Muravleva, K B; Petrova, S E

    2014-01-01

    The effects of the neurohumoral status on the EEG alpha - activity indices were studied in a within-subject design with 78 women aged 18-27 years during 1-2 menstrual cycle. Psychometric and EEG indices of alpha waves basal body temperature, saliva progesterone and cortisol level were monitored every 2-3 days. Menstrual and follicular recording sessions occurred before the ovulatory temperature rise, luteal recording session--after increasing progesterone level more than 20% respect to previous day and premenstrual sessions after decreasing progesterone level more that 20% respect to previous day. The design consisted of rest and task periods EEG, EMG and ECG recordings. Half the subjects began during their menstrual phase and half began during their luteal phase. All 5 phases were compared for differences between psychometric features EEG alpha activity, EMG and ECG baseline resting levels, as well as for reactivity to cognitive task. The results showed menstrual phase differences in all psychometric and alpha EEG indices. The cognitive fluency, alpha peak frequency, alpha band width, power in alpha-2 frequency range are maximal at luteal, alpha visual activation and reactivity to cognitive task performance--at follicular phase. The hypothesis that the EEG alpha activity depends on the hormonal status supported by the positive association salivary progesterone level with the alpha peak frequency, power in the alpha-2 band and negative--with the power of the alpha-1 band. According these results, we conclude that psycho-physiological recording sessions with women might be provided with a glance to phase of menstrual cycle.

  12. An Inquiry into the Life Cycle of Systems of Inner Walls: Comparison of Masonry and Drywall

    Directory of Open Access Journals (Sweden)

    Karina Condeixa

    2015-06-01

    Full Text Available Life Cycle Assessment is a methodology that investigates impacts linked to a product or service during its entire life cycle. Life Cycle Assessment studies investigate processes and sub-processes in a fragmented way to ascertain their inputs, outputs and emissions and get an overview of the generating sources of their environmental loads. The lifecycle concept involves all direct and indirect processes of the studied object. This article aims to model the material flows in the masonry and drywall systems and internal walls in a Brazilian scenario, and calculate the climate change impacts generated by the transport of the component materials of the systems. Internal walls of a residential dwelling in Rio de Janeiro are analyzed from a qualitative inventory of all life cycles with an analysis of material flows, based on technical and academic literature. All Life Cycle Impact Assessment of the systems is carried out with international data from the database, and using the IPCC2013 method for climate change impacts. This study disregards the refurbishment and possible extensions within the use phase. Thus, the inventory identifies weaknesses of the systems while the impact assessment validates the results. This study allows us a complete understanding about the inner walls systems in the Brazilian scenario, evidencing its main weaknesses and subsidizes decision-making for the industry and for planning of the new buildings.

  13. General problems of metrology and indirect measuring in cardiology: error estimation criteria for indirect measurements of heart cycle phase durations

    Directory of Open Access Journals (Sweden)

    Konstantine K. Mamberger

    2012-11-01

    Full Text Available Aims This paper treats general problems of metrology and indirect measurement methods in cardiology. It is aimed at an identification of error estimation criteria for indirect measurements of heart cycle phase durations. Materials and methods A comparative analysis of an ECG of the ascending aorta recorded with the use of the Hemodynamic Analyzer Cardiocode (HDA lead versus conventional V3, V4, V5, V6 lead system ECGs is presented herein. Criteria for heart cycle phase boundaries are identified with graphic mathematical differentiation. Stroke volumes of blood SV calculated on the basis of the HDA phase duration measurements vs. echocardiography data are compared herein. Results The comparative data obtained in the study show an averaged difference at the level of 1%. An innovative noninvasive measuring technology originally developed by a Russian R & D team offers measuring stroke volume of blood SV with a high accuracy. Conclusion In practice, it is necessary to take into account some possible errors in measurements caused by hardware. Special attention should be paid to systematic errors.

  14. Nonautonomous linear system of the terrestrial carbon cycle

    Science.gov (United States)

    Luo, Y.

    2012-12-01

    Carbon cycle has been studied by uses of observation through various networks, field and laboratory experiments, and simulation models. Much less has been done on theoretical thinking and analysis to understand fundament properties of carbon cycle and then guide observatory, experimental, and modeling research. This presentation is to explore what would be the theoretical properties of terrestrial carbon cycle and how those properties can be used to make observatory, experimental, and modeling research more effective. Thousands of published data sets from litter decomposition and soil incubation studies almost all indicate that decay processes of litter and soil organic carbon can be well described by first order differential equations with one or more pools. Carbon pool dynamics in plants and soil after disturbances (e.g., wildfire, clear-cut of forests, and plows of soil for cropping) and during natural recovery or ecosystem restoration also exhibit characteristics of first-order linear systems. Thus, numerous lines of empirical evidence indicate that the terrestrial carbon cycle can be adequately described as a nonautonomous linear system. The linearity reflects the nature of the carbon cycle that carbon, once fixed by photosynthesis, is linearly transferred among pools within an ecosystem. The linear carbon transfer, however, is modified by nonlinear functions of external forcing variables. In addition, photosynthetic carbon influx is also nonlinearly influenced by external variables. This nonautonomous linear system can be mathematically expressed by a first-order linear ordinary matrix equation. We have recently used this theoretical property of terrestrial carbon cycle to develop a semi-analytic solution of spinup. The new methods have been applied to five global land models, including NCAR's CLM and CABLE models and can computationally accelerate spinup by two orders of magnitude. We also use this theoretical property to develop an analytic framework to

  15. Characterization of Al-Ti phases in cycled TiF3-enhanced Na2LiAlH6

    International Nuclear Information System (INIS)

    Nakamura, Y.; Fossdal, A.; Brinks, H.W.; Hauback, B.C.

    2006-01-01

    TiF 3 -enhanced Na 2 LiAlH 6 was investigated after dehydrogenation-hydrogenation cycles by synchrotron X-ray diffraction. There was no sign of Ti after ball-milling with TiF 3 , but two types of Al-Ti phases were observed in the cycled samples. In a sample after measuring five pressure-composition isotherms in the temperature range from 170 to 250 deg. C, a fcc phase with a = 3.987 A was observed. This phase is considered to be Al 3 Ti with the L1 2 structure. Samples after one or four cycles at selected temperatures between 170 and 250 deg. C showed diffraction from another fcc phase with a ∼ 4.03 A. This indicates formation of an Al 1-y Ti y solid-solution phase with y ∼ 0.15 similar to previously reported for cycled NaAlH 4 with Ti additives

  16. Secretory activity and cell cycle alteration of alveolar type II cells in the early and late phase after irradiation

    International Nuclear Information System (INIS)

    Willner, Jochen; Vordermark, Dirk; Schmidt, Michael; Gassel, Andreamaria; Flentje, Michael; Wirtz, Hubert

    2003-01-01

    Purpose: Type II cells and the surfactant system have been proposed to play a central role in pathogenesis of radiation pneumonitis. We analyzed the secretory function and proliferation parameters of alveolar type II cells in the early (until 24 h) and late phase (1-5 weeks) after irradiation (RT) in vitro and in vivo. Methods and Materials: Type II cells were isolated from rats according to the method of Dobbs. Stimulation of secretion was induced with terbutaline, adenosine triphosphate (ATP), and 12-O-tetradecanoylphorbol-13-acetate (TPA) for a 2-h period. Determination of secretion was performed using 3 H-labeled phosphatidylcholine. For the early-phase analysis, freshly isolated and adherent type II cells were irradiated in vitro with 9-21 Gy (stepwise increase of 3 Gy). Secretion stimulation was initiated 1, 6, 24, and 48 h after RT. For late-phase analysis, type II cells were isolated 1-5 weeks after 18 Gy whole lung or sham RT. Each experiment was repeated at least fivefold. Flow cytometry was used to determine cell cycle distribution and proliferating cell nuclear antigen index. Results: During the early-phase (in vitro) analysis, we found a normal stimulation of surfactant secretion in irradiated, as well as unirradiated, cells. No change in basal secretion and no dose effect were seen. During the late phase, 1-5 weeks after whole lung RT, we observed enhanced secretory activity for all secretagogues and a small increase in basal secretion in Weeks 3 and 4 (pneumonitis phase) compared with controls. The total number of isolated type II cells, as well as the rate of viable cells, decreased after the second post-RT week. Cell cycle alterations suggesting an irreversible G 2 /M block occurred in the second post-RT week and did not resolve during the observation period. The proliferating cell nuclear antigen index of type II cells from irradiated rats did not differ from that of controls. Conclusion: In contrast to literature data, we observed no direct

  17. Guidance for the application of an assessment methodology for innovative nuclear energy systems. INPRO manual - Overview of the methodology. Vol. 1 of 9 of the final report of phase 1 of the International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO) including a CD-ROM comprising all volumes

    International Nuclear Information System (INIS)

    2008-11-01

    The International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO) was initiated in the year 2000, based on a resolution of the IAEA General Conference (GC(44)/RES/21). The main objectives of INPRO are (1) to help to ensure that nuclear energy is available to contribute in fulfilling energy needs in the 21st century in a sustainable manner, (2) to bring together both technology holders and technology users to consider jointly the international and national actions required to achieve desired innovations in nuclear reactors and fuel cycles; and (3) to create a forum to involve all relevant stakeholders that will have an impact on, draw from, and complement the activities of existing institutions, as well as ongoing initiatives at the national and international level. This document follows the guidelines of the INPRO report 'Methodology for the assessment of innovative nuclear reactors and fuel cycles, Report of Phase 1B (first part) of the International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO)', IAEA-TECDOC-1434 (2004), together with its previous report Guidance for the evaluation for innovative nuclear reactors and fuel cycles, Report of Phase 1A of the International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO), IAEA-TECDOC-1362 (2003). This INPRO manual is comprised of an overview volume (laid out in this report), and eight additional volumes (available on a CD-ROM attached to the inside back cover of this report) covering the areas of economics (Volume 2), infrastructure (Volume 3), waste management (Volume 4), proliferation resistance (Volume 5), physical protection (Volume 6), environment (Volume 7), safety of reactors (Volume 8), and safety of nuclear fuel cycle facilities (Volume 9). The overview volume sets out the philosophy of INPRO and a general discussion of the INPRO methodology. This overview volume discusses the relationship of INPRO with the UN concept of sustainability to demonstrate how the

  18. Cycle analysis of MCFC/gas turbine system

    Directory of Open Access Journals (Sweden)

    Musa Abdullatif

    2017-01-01

    Full Text Available High temperature fuel cells such as the solid oxide fuel cell (SOFC and the molten carbonate fuel cell (MCFC are considered extremely suitable for electrical power plant application. The molten carbonate fuel cell (MCFC performances is evaluated using validated model for the internally reformed (IR fuel cell. This model is integrated in Aspen Plus™. Therefore, several MCFC/Gas Turbine systems are introduced and investigated. One of this a new cycle is called a heat recovery (HR cycle. In the HR cycle, a regenerator is used to preheat water by outlet air compressor. So the waste heat of the outlet air compressor and the exhaust gases of turbine are recovered and used to produce steam. This steam is injected in the gas turbine, resulting in a high specific power and a high thermal efficiency. The cycles are simulated in order to evaluate and compare their performances. Moreover, the effects of an important parameters such as the ambient air temperature on the cycle performance are evaluated. The simulation results show that the HR cycle has high efficiency.

  19. Cycle analysis of MCFC/gas turbine system

    Science.gov (United States)

    Musa, Abdullatif; Alaktiwi, Abdulsalam; Talbi, Mosbah

    2017-11-01

    High temperature fuel cells such as the solid oxide fuel cell (SOFC) and the molten carbonate fuel cell (MCFC) are considered extremely suitable for electrical power plant application. The molten carbonate fuel cell (MCFC) performances is evaluated using validated model for the internally reformed (IR) fuel cell. This model is integrated in Aspen Plus™. Therefore, several MCFC/Gas Turbine systems are introduced and investigated. One of this a new cycle is called a heat recovery (HR) cycle. In the HR cycle, a regenerator is used to preheat water by outlet air compressor. So the waste heat of the outlet air compressor and the exhaust gases of turbine are recovered and used to produce steam. This steam is injected in the gas turbine, resulting in a high specific power and a high thermal efficiency. The cycles are simulated in order to evaluate and compare their performances. Moreover, the effects of an important parameters such as the ambient air temperature on the cycle performance are evaluated. The simulation results show that the HR cycle has high efficiency.

  20. High-speed thermal cycling system and method of use

    Science.gov (United States)

    Hansen, A.D.A.; Jaklevic, J.M.

    1996-04-16

    A thermal cycling system and method of use are described. The thermal cycling system is based on the circulation of temperature-controlled water directly to the underside of thin-walled polycarbonate plates. The water flow is selected from a manifold fed by pumps from heated reservoirs. The plate wells are loaded with typically 15-20 microliters of reagent mix for the PCR process. Heat transfer through the thin polycarbonate is sufficiently rapid that the contents reach thermal equilibrium with the water in less than 15 seconds. Complete PCR amplification runs of 40 three-step cycles have been performed in as little as 14.5 minutes, with the results showing substantially enhanced specificity compared to conventional technology requiring run times in excess of 100 minutes. The plate clamping station is designed to be amenable to robotic loading and unloading of the system. It includes a heated lid, thus eliminating the need for mineral oil overlay of the reactants. The present system includes three or more plate holder stations, fed from common reservoirs but operating with independent switching cycles. The system can be modularly expanded. 13 figs.

  1. Tracking the evolution of the disaster management cycle: A general system theory approach

    Directory of Open Access Journals (Sweden)

    Christo Coetzee

    2012-12-01

    Full Text Available Officials and scholars have used the disaster management cycle for the past 30 years to explain and manage impacts. Although very little understanding and agreement exist in terms of where the concept originated it is the purpose of this article to address the origins of the disaster management cycle. To achieve this, general system theory concepts of isomorphisms, equifinality, open systems and feedback arrangements were applied to linear disaster phase research (which emerged in the 1920s and disaster management cycles. This was done in order to determine whether they are related concepts with procedures such as emergency, relief, recovery and rehabilitation.

  2. Guidance for the application of an assessment methodology for innovative nuclear energy systems. INPRO manual - Infrastructure. Vol. 3 of the final report of phase 1 of the International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO)

    International Nuclear Information System (INIS)

    2008-11-01

    The International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO) was initiated in the year 2000, based on a resolution of the IAEA General Conference (GC(44)/RES/21). The main objectives of INPRO are (1) to help to ensure that nuclear energy is available to contribute in fulfilling energy needs in the 21st century in a sustainable manner, (2) to bring together both technology holders and technology users to consider jointly the international and national actions required to achieve desired innovations in nuclear reactors and fuel cycles; and (3) to create a forum to involve all relevant stakeholders that will have an impact on, draw from, and complement the activities of existing institutions, as well as ongoing initiatives at the national and international level. The INPRO manual is comprised of an overview volume and eight additional volumes covering the areas of economics (Volume 2), infrastructure (Volume 3, outlined here), waste management (Volume 4), proliferation resistance (Volume 5), physical protection (Volume 6), environment (Volume 7), safety of reactors (Volume 8), and safety of nuclear fuel cycle facilities (Volume 9). Within INPRO, the term infrastructure can be defined as the collection of capabilities of institutions involved in a nuclear power program in a given country that are necessary for the successful deployment (or enlargement) and operation of an INS, including legal and institutional, industrial and economic, and socio-political features. Within INPRO, the definition of an INS includes activities and facilities (i.e. components) at both the front end of the fuel cycle (e.g., mining, enrichment, fuel fabrication) and the back end (e.g., reprocessing, storage, and repository) (Section 4.2.1 of Volume 1 of the INPRO manual. Consequently, within INPRO, such facilities are not considered to be a part of the INPRO area of infrastructure, albeit that they influence the size of the necessary infrastructure required in a given

  3. SIMULATION STUDY OF HEMISPHERIC PHASE-ASYMMETRY IN THE SOLAR CYCLE

    Energy Technology Data Exchange (ETDEWEB)

    Shukuya, D.; Kusano, K., E-mail: kusano@nagoya-u.jp [Institute for Space-Earth Environmental Research, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Aichi 4648601 (Japan)

    2017-01-20

    Observations of the Sun suggest that solar activities systematically create north–south hemispheric asymmetries. For instance, the hemisphere in which sunspot activity is more active tends to switch after the early half of each solar cycle. Svalgaard and Kamide recently pointed out that the time gaps of polar field reversal between the northern and southern hemispheres are simply consequences of the asymmetry of sunspot activity. However, the mechanism underlying the asymmetric feature in solar cycle activity is not yet well understood. In this paper, in order to explain the cause of the asymmetry from the theoretical point of view, we investigate the relationship between the dipole- and quadrupole-type components of the magnetic field in the solar cycle using the mean-field theory based on the flux transport dynamo model. As a result, we found that there are two different attractors of the solar cycle, in which either the north or the south polar field is first reversed, and that the flux transport dynamo model explains well the phase-asymmetry of sunspot activity and the polar field reversal without any ad hoc source of asymmetry.

  4. Oscillating systems with cointegrated phase processes

    DEFF Research Database (Denmark)

    Østergaard, Jacob; Rahbek, Anders; Ditlevsen, Susanne

    2017-01-01

    We present cointegration analysis as a method to infer the network structure of a linearly phase coupled oscillating system. By defining a class of oscillating systems with interacting phases, we derive a data generating process where we can specify the coupling structure of a network...... that resembles biological processes. In particular we study a network of Winfree oscillators, for which we present a statistical analysis of various simulated networks, where we conclude on the coupling structure: the direction of feedback in the phase processes and proportional coupling strength between...... individual components of the system. We show that we can correctly classify the network structure for such a system by cointegration analysis, for various types of coupling, including uni-/bi-directional and all-to-all coupling. Finally, we analyze a set of EEG recordings and discuss the current...

  5. Knee joint kinaesthesia and neuromuscular coordination during three phases of the menstrual cycle in moderately active women.

    Science.gov (United States)

    Fridén, Cecilia; Hirschberg, Angelica Lindén; Saartok, Tönu; Renström, Per

    2006-04-01

    An increased incidence of sports related injuries in the premenstrual phase as well as in the menstrual phase of the menstrual cycle has been described. This may be explained by alterations in proprioception and neuromuscular coordination due to hormonal variations. Prospective, within women analysis of knee joint kinesthesia and neuromuscular coordination were performed by repeated measures analysis of variance in three hormonally verified phases of three consecutive menstrual cycles. Thirty-two healthy, moderately active female subjects volunteered to participate in the study. Twenty-five of the subjects performed at least one hormonally verified menstrual cycle. A specially designed device was used to investigate knee joint kinaesthesia and neuromuscular coordination was measured with the square hop test. These tests were carried out in the menstrual phase, ovulation phase and premenstrual phase determined by hormone analyses in three consecutive menstrual cycles. An impaired knee joint kinaesthesia was detected in the premenstrual phase and the performance of square hop test was significantly improved in the ovulation phase compared to the other two phases. The results of this study indicate that the variation of sex hormones in the menstrual cycle has an effect on performance of knee joint kinaesthesia and neuromuscular coordination.

  6. In situ survey of life cycle phases of the coccolithophore Emiliania huxleyi (Haptophyta).

    Science.gov (United States)

    Frada, Miguel J; Bidle, Kay D; Probert, Ian; de Vargas, Colomban

    2012-06-01

    The cosmopolitan coccolithophore Emiliania huxleyi is characterized by a strongly differentiated haplodiplontic life cycle consisting of a diploid phase, generally bearing coccoliths (calcified) but that can be also non-calcified, and a non-calcified biflagellated haploid phase. Given most studies have focused on the bloom-producing calcified phase, there is little-to-no information about non-calcified cells in nature. Using field mesocoms as experimental platforms, we quantitatively surveyed calcified and non-calcified cells using the combined calcareous detection fluorescent in situ hybridization (COD-FISH) method and qualitatively screened for haploid specific transcripts using reverse transcription-PCR during E. huxleyi bloom successions. Diploid, calcified cells formed dense blooms that were followed by the massive proliferation of E. huxleyi viruses (EhVs), which caused bloom demise. Non-calcified cells were also detected throughout the experiment, accounting for a minor fraction of the population but becoming progressively more abundant during mid-late bloom periods concomitant with EhV burst. Non-calcified cell growth also paralleled a distinct window of haploid-specific transcripts and the appearance of autotrophic flagellates morphologically similar to haploid cells, both of which are suggestive of meiosis and sexual life cycling during natural blooms of this prominent marine phytoplankton species. © 2012 Society for Applied Microbiology and Blackwell Publishing Ltd.

  7. Centres and limit cycles for an extended Kukles system

    Directory of Open Access Journals (Sweden)

    Jane M. Pearson

    2007-09-01

    Full Text Available We present conditions for the origin to be a centre for a class of cubic systems. Some of the centre conditions are determined by finding complicated invariant functions. We also investigate the coexistence of fine foci and the simultaneous bifurcation of limit cycles from them.

  8. Closed Cycle Solar Refrigeration with the Calcium Chloride System ...

    African Journals Online (AJOL)

    A closed cycle solid absorption intermittent refrigerator, using CaC12 absorbent and NH3 refrigerant, was constructed and tested to obtain the instantaneous and cumulative available overall COP. The combined collector/absorber/generator unit had double glazing of 1.14 m2 exposed areas. The system was fitted with a ...

  9. Battery energy storage systems life cycle costs case studies

    Energy Technology Data Exchange (ETDEWEB)

    Swaminathan, S.; Miller, N.F.; Sen, R.K. [SENTECH, Inc., Bethesda, MD (United States)

    1998-08-01

    This report presents a comparison of life cycle costs between battery energy storage systems and alternative mature technologies that could serve the same utility-scale applications. Two of the battery energy storage systems presented in this report are located on the supply side, providing spinning reserve and system stability benefits. These systems are compared with the alternative technologies of oil-fired combustion turbines and diesel generators. The other two battery energy storage systems are located on the demand side for use in power quality applications. These are compared with available uninterruptible power supply technologies.

  10. Cell cycle phase dependent emergence of thymidylate synthase studied by monoclonal antibody (M-TS-4).

    Science.gov (United States)

    Shibui, S; Hoshino, T; Iwasaki, K; Nomura, K; Jastreboff, M M

    1989-05-01

    A method of identifying thymidylate synthase (TS) at the cellular level was developed using anti-TS monoclonal antibody (M-TS-4), a monoclonal antibody created against purified TS from a HeLa cell line. In HeLa cells and four human glioma cell lines (U-251, U-87, 343-MGA, and SF-188), TS was identified primarily in the cytoplasm. Autoradiographic and flow cytometric studies showed that TS appeared mainly in the G1 phase and subsided early in the S phase; thus, the G1 phase can be divided into TS-positive and -negative fractions. Nuclear TS was not demonstrated unequivocally with M-TS-4, and the relationship between nuclear TS and DNA synthesis could not be determined. Although the percentage of TS-positive cells was larger than the S-phase fraction measured by autoradiography after a pulse of tritiated thymidine or by the immunoperoxidase method using BUdR, the ratios were within a similar range (1.2-1.4) in all cell lines studied. Therefore, the S-phase fraction can be estimated indirectly from the percentage of TS-positive cells measured by M-TS-4. Because the emergence of TS detected by our method is cell cycle dependent, M-TS-4 may be useful for biochemical studies of TS and for cytokinetic analysis.

  11. Solar energetic particle events during the rise phases of solar cycles 23 and 24

    Science.gov (United States)

    Chandra, R.; Gopalswamy, N.; Mäkelä, P.; Xie, H.; Yashiro, S.; Akiyama, S.; Uddin, W.; Srivastava, A. K.; Joshi, N. C.; Jain, R.; Awasthi, A. K.; Manoharan, P. K.; Mahalakshmi, K.; Dwivedi, V. C.; Choudhary, D. P.; Nitta, N. V.

    2013-12-01

    We present a comparative study of the properties of coronal mass ejections (CMEs) and flares associated with the solar energetic particle (SEP) events in the rising phases of solar cycles (SC) 23 (1996-1998) (22 events) and 24 (2009-2011) (20 events), which are associated with type II radio bursts. Based on the SEP intensity, we divided the events into three categories, i.e. weak (intensity pfu), minor (1 pfu pfu) and major (intensity ⩾ 10 pfu) events. We used the GOES data for the minor and major SEP events and SOHO/ERNE data for the weak SEP event. We examine the correlation of SEP intensity with flare size and CME properties. We find that most of the major SEP events are associated with halo or partial halo CMEs originating close to the sun center and western-hemisphere. The fraction of halo CMEs in SC 24 is larger than the SC 23. For the minor SEP events one event in SC23 and one event in SC24 have widths < 120° and all other events are associated with halo or partial halo CMEs as in the case of major SEP events. In case of weak SEP events, majority (more than 60%) of events are associated with CME width < 120°. For both the SC the average CMEs speeds are similar. For major SEP events, average CME speeds are higher in comparison to minor and weak events. The SEP event intensity and GOES X-ray flare size are poorly correlated. During the rise phase of solar cycle 23 and 24, we find north-south asymmetry in the SEP event source locations: in cycle 23 most sources are located in the south, whereas during cycle 24 most sources are located in the north. This result is consistent with the asymmetry found with sunspot area and intense flares.

  12. Achievement report for 1st phase (fiscal 1974-80) Sunshine Program research and development - Hydrogen energy. Research on hydrogen production technology using thermochemical process (Research on cycles of Fe systems etc.); 1974-1980 nendo suiso energy seika hokokusho. Netsu kagakuho ni yoru suiso seizo gijutsu no kenkyu (tetsukei cycle nado no kenkyu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1981-03-01

    Collected in this report are the results of efforts of the Government Industrial Research Institute, Osaka, in the 7-year period that began in fiscal 1974. The Institute, after looking for basic reactions in thermochemical cycles which are promising, has come to propose a new cycle in which iron and bromine are the reactants. In the research, the Fe-Br reaction is divided into a hydrogen generating loop and an oxygen generating loop, both to be developed into devices. Problems in developing them into a cycle are isolated, and solved. In the hydrogen generating loop, the use of a molten salt is contrived for the prevention of reduction in the reactivity of the Fe{sub 3}O{sub 4} to be generated, and now it is expected that the problem will be solved. No problem is detected in the oxygen generating loop. The process is now accepted as a superb one. As for the materials for the Fe-Br-based cycle apparatus, important tasks have to be undertaken since existing materials cannot be used as is. Besides, thermal efficiency etc. are estimated for a new As-Br-based hybrid cycle and the Fe-Br-based cycle. (NEDO)

  13. Expression of the epidermal growth factor system in human endometrium during the menstrual cycle

    DEFF Research Database (Denmark)

    Ejskjaer, Kirsten; Sørensen, B S; Poulsen, Steen Seier

    2005-01-01

    The epidermal growth factor (EGF) system is ubiquitous in humans and plays fundamental roles in embryogenesis, development, proliferation and differentiation. As the endometrium of fertile women is characterized by proliferation and differentiation, we hypothesize a role for the EGF system....... Fourteen premenopausal women had endometrial samples removed on day 6 +/- 1 and day 6 +/- 1 and 12 +/- 1 after ovulation during one menstrual cycle. RNA was extracted and analysed by real-time PCR, and immunohistochemistry was performed to localize the components of the EGF system. Human EGF Receptor 1...... (HER1) showed highest expression during the proliferative phase, HER2 and HER4 during the early and HER3 during the late secretory phase. Amphiregulin (AR) and transforming growth factor alpha (TGFalpha) expression is highest in proliferative phase. Heparin binding (HB)-EGF and betacellulin (BCL) show...

  14. Determination of cell cycle phases in live B16 melanoma cells using IRMS.

    Science.gov (United States)

    Bedolla, Diana E; Kenig, Saša; Mitri, Elisa; Ferraris, Paolo; Marcello, Alessandro; Grenci, Gianluca; Vaccari, Lisa

    2013-07-21

    The knowledge of cell cycle phase distribution is of paramount importance for understanding cellular behaviour under normal and stressed growth conditions. This task is usually assessed using Flow Cytometry (FC) or immunohistochemistry. Here we report on the use of FTIR microspectroscopy in Microfluidic Devices (MD-IRMS) as an alternative technique for studying cell cycle distribution in live cells. Asynchronous, S- and G0-synchronized B16 mouse melanoma cells were studied by running parallel experiments based on MD-IRMS and FC using Propidium Iodide (PI) staining. MD-IRMS experiments have been done using silicon-modified BaF2 devices, where the thin silicon layer prevents BaF2 dissolution without affecting the transparency of the material and therefore enabling a better assessment of the Phosphate I (PhI) and II (PhII) bands. Hierarchical Cluster Analysis (HCA) of cellular microspectra in the 1300-1000 cm(-1) region pointed out a distribution of cells among clusters, which is in good agreement with FC results among G0/G1, S and G2/M phases. The differentiation is mostly driven by the intensity of PhI and PhII bands. In particular, PhI almost doubles from the G0/G1 to G2/M phase, in agreement with the trend followed by nucleic acids during cellular progression. MD-IRMS is then proposed as a powerful method for the in situ determination of the cell cycle stage of an individual cell, without any labelling or staining, which gives the advantage of possibly monitoring specific cellular responses to several types of stimuli by clearly separating the spectral signatures related to the cellular response from those of cells that are normally progressing.

  15. Limit Cycle Analysis in a Class of Hybrid Systems

    Directory of Open Access Journals (Sweden)

    Antonio Favela-Contreras

    2016-01-01

    Full Text Available Hybrid systems are those that inherently combine discrete and continuous dynamics. This paper considers the hybrid system model to be an extension of the discrete automata associating a continuous evolution with each discrete state. This model is called the hybrid automaton. In this work, we achieve a mathematical formulation of the steady state and we show a way to obtain the initial conditions region to reach a specific limit cycle for a class of uncoupled and coupled continuous-linear hybrid systems. The continuous-linear term is used in the sense of the system theory and, in this sense, continuous-linear hybrid automata will be defined. Thus, some properties and theorems that govern the hybrid automata dynamic behavior to evaluate a limit cycle existence have been established; this content is explained under a theoretical framework.

  16. Bunching phase evolution of short-pulse FEL oscillator system

    CERN Document Server

    Song, S B; Choi, D I

    2000-01-01

    We studied numerically the short-pulse FEL oscillator system using properly defined bunching phase theta sub B and PSI sub B. In stable operation, we have found that the optical field 'locks' the phase to pi/2 at the trailing edge, which gives the maximum gain. Moreover, electrons can be detrapped from ponderomotive bucket due to the spatial variation of the optical field, and this detrapping effect is a major cause of the limit cycle oscillation of the system. The 'bump' of the output power during the amplification usually exists at the near-perfect cavity synchronism regime, which can be explained as the change of the matching condition between electron micropulse and optical pulse.

  17. Control system options and strategies for supercritical CO2 cycles.

    Energy Technology Data Exchange (ETDEWEB)

    Moisseytsev, A.; Kulesza, K. P.; Sienicki, J. J.; Nuclear Engineering Division; Oregon State Univ.

    2009-06-18

    The Supercritical Carbon Dioxide (S-CO{sub 2}) Brayton Cycle is a promising alternative to Rankine steam cycle and recuperated gas Brayton cycle energy converters for use with Sodium-Cooled Fast Reactors (SFRs), Lead-Cooled Fast Reactors (LFRs), as well as other advanced reactor concepts. The S-CO{sub 2} Brayton Cycle offers higher plant efficiencies than Rankine or recuperated gas Brayton cycles operating at the same liquid metal reactor core outlet temperatures as well as reduced costs or size of key components especially the turbomachinery. A new Plant Dynamics Computer Code has been developed at Argonne National Laboratory for simulation of a S-CO{sub 2} Brayton Cycle energy converter coupled to an autonomous load following liquid metal-cooled fast reactor. The Plant Dynamics code has been applied to investigate the effectiveness of a control strategy for the S-CO{sub 2} Brayton Cycle for the STAR-LM 181 MWe (400 MWt) Lead-Cooled Fast Reactor. The strategy, which involves a combination of control mechanisms, is found to be effective for controlling the S-CO{sub 2} Brayton Cycle over the complete operating range from 0 to 100 % load for a representative set of transient load changes. While the system dynamic analysis of control strategy performance for STARLM is carried out for a S-CO{sub 2} Brayton Cycle energy converter incorporating an axial flow turbine and compressors, investigations of the S-CO{sub 2} Brayton Cycle have identified benefits from the use of centrifugal compressors which offer a wider operating range, greater stability near the critical point, and potentially further cost reductions due to fewer stages than axial flow compressors. Models have been developed at Argonne for the conceptual design and performance analysis of centrifugal compressors for use in the SCO{sub 2} Brayton Cycle. Steady state calculations demonstrate the wider operating range of centrifugal compressors versus axial compressors installed in a S-CO{sub 2} Brayton Cycle as

  18. Control system options and strategies for supercritical CO2 cycles

    International Nuclear Information System (INIS)

    Moisseytsev, A.; Kulesza, K.P.; Sienicki, J.J.

    2009-01-01

    The Supercritical Carbon Dioxide (S-CO 2 ) Brayton Cycle is a promising alternative to Rankine steam cycle and recuperated gas Brayton cycle energy converters for use with Sodium-Cooled Fast Reactors (SFRs), Lead-Cooled Fast Reactors (LFRs), as well as other advanced reactor concepts. The S-CO 2 Brayton Cycle offers higher plant efficiencies than Rankine or recuperated gas Brayton cycles operating at the same liquid metal reactor core outlet temperatures as well as reduced costs or size of key components especially the turbomachinery. A new Plant Dynamics Computer Code has been developed at Argonne National Laboratory for simulation of a S-CO 2 Brayton Cycle energy converter coupled to an autonomous load following liquid metal-cooled fast reactor. The Plant Dynamics code has been applied to investigate the effectiveness of a control strategy for the S-CO 2 Brayton Cycle for the STAR-LM 181 MWe (400 MWt) Lead-Cooled Fast Reactor. The strategy, which involves a combination of control mechanisms, is found to be effective for controlling the S-CO 2 Brayton Cycle over the complete operating range from 0 to 100 % load for a representative set of transient load changes. While the system dynamic analysis of control strategy performance for STARLM is carried out for a S-CO 2 Brayton Cycle energy converter incorporating an axial flow turbine and compressors, investigations of the S-CO 2 Brayton Cycle have identified benefits from the use of centrifugal compressors which offer a wider operating range, greater stability near the critical point, and potentially further cost reductions due to fewer stages than axial flow compressors. Models have been developed at Argonne for the conceptual design and performance analysis of centrifugal compressors for use in the SCO 2 Brayton Cycle. Steady state calculations demonstrate the wider operating range of centrifugal compressors versus axial compressors installed in a S-CO 2 Brayton Cycle as well as the benefits in expanding the range

  19. New concepts for organic Rankine cycle power systems

    OpenAIRE

    Casati, E.I.M.

    2014-01-01

    Energy provision is one of the major challenges for the Human Society, and it is increasingly clear that the current production/consumption model is not sustainable. The envisaged energy system is smarter, more decentralised and integrated. Energy conversion systems based on the organic Rankine thermodynamic cycle (ORC) have the potential to play a major role in this framework, being one of the most proven solutions for the exploitation of external thermal sources in the power-output range fr...

  20. Ammonia control in children with urea cycle disorders (UCDs); Phase 2 comparison of sodium phenylbutyrate and glycerol phenylbutyrate☆

    OpenAIRE

    Lichter-Konecki, Uta; Diaz, G.A.; Merritt, J.L.; Feigenbaum, A.; Jomphe, C.; Marier, J.F.; Beliveau, M.; Mauney, J.; Dickinson, K.; Martinez, A.; Mokhtarani, M.; Scharschmidt, B.; Rhead, W.

    2011-01-01

    Twenty four hour ammonia profiles and correlates of drug effect were examined in a phase 2 comparison of sodium phenylbutyrate (NaPBA) and glycerol phenylbutyrate (GPB or HPN-100), an investigational drug being developed for urea cycle disorders (UCDs).

  1. Comparative techniques for nuclear fuel cycle waste management systems

    International Nuclear Information System (INIS)

    Pelto, P.J.; Voss, J.W.

    1979-09-01

    A safety assessment approach for the evaluation of predisposal waste management systems is described and applied to selected facilities in the light water reactor (LWR) once-through fuel cycle and a potential coprocessed UO 2 -PuO 2 fuel cycle. This approach includes a scoping analysis on pretreatment waste streams and a more detailed analysis on proposed waste management processes. The primary evaluation parameters used in this study include radiation exposures to the public from radionuclide releases from normal operations and potential accidents, occupational radiation exposure from normal operations, and capital and operating costs. On an overall basis, the waste management aspects of the two fuel cycles examined are quite similar. On an individual facility basis, the fuel coprocessing plant has the largest waste management impact

  2. Life cycle assessment of a biomass gasification combined-cycle power system

    Energy Technology Data Exchange (ETDEWEB)

    Mann, M.K.; Spath, P.L.

    1997-12-01

    The potential environmental benefits from biomass power are numerous. However, biomass power may also have some negative effects on the environment. Although the environmental benefits and drawbacks of biomass power have been debated for some time, the total significance has not been assessed. This study serves to answer some of the questions most often raised in regard to biomass power: What are the net CO{sub 2} emissions? What is the energy balance of the integrated system? Which substances are emitted at the highest rates? What parts of the system are responsible for these emissions? To provide answers to these questions, a life cycle assessment (LCA) of a hypothetical biomass power plant located in the Midwest United States was performed. LCA is an analytical tool for quantifying the emissions, resource consumption, and energy use, collectively known as environmental stressors, that are associated with converting a raw material to a final product. Performed in conjunction with a technoeconomic feasibility study, the total economic and environmental benefits and drawbacks of a process can be quantified. This study complements a technoeconomic analysis of the same process, reported in Craig and Mann (1996) and updated here. The process studied is based on the concept of power Generation in a biomass integrated gasification combined cycle (BIGCC) plant. Broadly speaking, the overall system consists of biomass production, its transportation to the power plant, electricity generation, and any upstream processes required for system operation. The biomass is assumed to be supplied to the plant as wood chips from a biomass plantation, which would produce energy crops in a manner similar to the way food and fiber crops are produced today. Transportation of the biomass and other materials is by both rail and truck. The IGCC plant is sized at 113 MW, and integrates an indirectly-heated gasifier with an industrial gas turbine and steam cycle. 63 refs., 34 figs., 32 tabs.

  3. Life cycle assessment of a biomass gasification combined-cycle power system

    Energy Technology Data Exchange (ETDEWEB)

    Mann, M.K.; Spath, P.L.

    1997-12-01

    The potential environmental benefits from biomass power are numerous. However, biomass power may also have some negative effects on the environment. Although the environmental benefits and drawbacks of biomass power have been debated for some time, the total significance has not been assessed. This study serves to answer some of the questions most often raised in regard to biomass power: What are the net CO{sub 2} emissions? What is the energy balance of the integrated system? Which substances are emitted at the highest rates? What parts of the system are responsible for these emissions? To provide answers to these questions, a life cycle assessment (LCA) of a hypothetical biomass power plant located in the Midwest United States was performed. LCA is an analytical tool for quantifying the emissions, resource consumption, and energy use, collectively known as environmental stressors, that are associated with converting a raw material to a final product. Performed in conjunction with a t echnoeconomic feasibility study, the total economic and environmental benefits and drawbacks of a process can be quantified. This study complements a technoeconomic analysis of the same process, reported in Craig and Mann (1996) and updated here. The process studied is based on the concept of power Generation in a biomass integrated gasification combined cycle (BIGCC) plant. Broadly speaking, the overall system consists of biomass production, its transportation to the power plant, electricity generation, and any upstream processes required for system operation. The biomass is assumed to be supplied to the plant as wood chips from a biomass plantation, which would produce energy crops in a manner similar to the way food and fiber crops are produced today. Transportation of the biomass and other materials is by both rail and truck. The IGCC plant is sized at 113 MW, and integrates an indirectly-heated gasifier with an industrial gas turbine and steam cycle. 63 refs., 34 figs., 32 tabs.

  4. Performance analysis of Brayton cycle system for space power reactor

    International Nuclear Information System (INIS)

    Li Zhi; Yang Xiaoyong; Zhao Gang; Wang Jie; Zhang Zuoyi

    2017-01-01

    The closed Brayton cycle system now is the potential choice as the power conversion system for High Temperature Gas-cooled Reactors because of its high energy conversion efficiency and compact configuration. The helium is the best working fluid for the system for its chemical stability and small neutron absorption cross section. However, the Helium has small mole mass and big specific volume, which would lead to larger pipes and heat exchanger. What's more, the big compressor enthalpy rise of helium would also lead to an unacceptably large number of compressor's stage. For space use, it's more important to satisfy the limit of the system's volume and mass, instead of the requirement of the system's thermal capacity. So Noble-Gas binary mixture of helium and xenon is presented as the working fluid for space Brayton cycle. This paper makes a mathematical model for space Brayton cycle system by Fortran language, then analyzes the binary mixture of helium and xenon's properties and effects on power conversion units of the space power reactor, which would be helpful to understand and design the space power reactor. The results show that xenon would lead to a worse system's thermodynamic property, the cycle's efficiency and specific power decrease as xenon's mole fraction increasing. On the other hand, proper amount of xenon would decrease the enthalpy changes in turbomachines, which would be good for turbomachines' design. Another optimization method – the specific power optimization is also proposed to make a comparison. (author)

  5. Effect of thermal cycling on martensitic transformation and mechanical strengthening of stainless steels – A phase-field study

    DEFF Research Database (Denmark)

    Yeddu, Hemantha Kumar; Shaw, Brian A.; Somers, Marcel A. J.

    2017-01-01

    A 3D elastoplastic phase-field model is used to study the effect of thermal cycling on martensitic transformationas well as on mechanical strengthening of both austenite and martensite in stainless steel. The results show that with an increasing number of thermal cycles, martensite becomes more...

  6. Development of Phase Lock Loop System for Synchronisation of a Hybrid System with the Grid

    Directory of Open Access Journals (Sweden)

    A. S. Abubakar

    2016-06-01

    Full Text Available Phase locked loop (PLL is an important part of the control unit of the grid connected power converter. The method of zero crossing detection (ZCD does not produce accurate phase information when grid is non-ideal. In this work, a synchronous reference frame (SRF PLL method to obtain accurate phase information when the grid voltages are unbalanced is proposed. The performances of the PLL have been verified for ideal and abnormal grid conditions such as unbalance, voltage sag, faults condition etc. Based on the results obtained, the developed PLL gives better fault ride when unbalances in the three phase input signals are overall handled well by the PLL system as it locks the two signal back within the first cycle. It also overcomes a phase jump after 5 milli-seconds from the time the fault was introduced and performs better tracking of the grid voltage and that of the renewable energy source.

  7. Development of Phase Lock Loop System for Synchronisation of a Hybrid System with the Grid

    Directory of Open Access Journals (Sweden)

    A. S. Abubakar

    2016-12-01

    Full Text Available Phase locked loop (PLL is an important part of the control unit of the grid connected power converter. The method of zero crossing detection (ZCD does not produce accurate phase information when grid is non-ideal. In this work, a synchronous reference frame (SRF PLL method to obtain accurate phase information when the grid voltages are unbalanced is proposed. The performances of the PLL have been verified for ideal and abnormal grid conditions such as unbalance, voltage sag, faults condition etc. Based on the results obtained, the developed PLL gives better fault ride when unbalances in the three phase input signals are overall handled well by the PLL system as it locks the two signal back within the first cycle. It also overcomes a phase jump after 5 milli-seconds from the time the fault was introduced and performs better tracking of the grid voltage and that of the renewable energy source.

  8. Effects of oestradiol for luteal phase support in fresh embryo transfer cycles: A retrospective cohort study.

    Science.gov (United States)

    Zhao, Wei; Liu, Yifeng; Xu, Peng; Wu, Yiqing; Chen, Kai; Guo, Xiaoyan; Zhang, Fan; Huang, Yun; Zhu, Linlin; Zhang, Runjv; Zhang, Dan

    2018-05-12

    Any benefit of oestradiol supplementation with progesterone for luteal support after fresh embryo transfer in in vitro fertilisation/intracytoplasmic sperm injection (IVF/ICSI) cycles remains controversial. In this study, we further addressed this question in cycles using gonadotropin-releasing hormone (GnRH) agonist for ovarian stimulation. A retrospective cohort study in a tertiary teaching and research hospital. A total of 1602 patients were given oestradiol valerate (E) in addition to progesterone (P) as luteal support. One thousand six hundred and two patients receiving progesterone alone were selected as the control group. Live birth rate. Secondary measures included clinical pregnancy rate, miscarriage rate and premature birth rate. Clinical pregnancy and live birth rates were similar for the P alone vs the P+E group. In cycles with oestradiol (E2) levels less than 5000 pmol/L on the day of hCG trigger, E supplementation resulted in a significantly higher live birth rate (23.44% vs 32.92%, OR = 1.60 [95% CI 1.05 to 2.46]). In cycles with oestradiol levels 5000 to 10 000 pmol/L on the day of hCG trigger, E supplementation did not increase the live birth rate (34.43% vs 35.42%, OR = 0.90 [95% CI 0.80 to 1.01]). In cycles with oestradiol levels over 10 000 pmol/L on the day of hCG trigger, the live birth rate was significantly lower (36.83% vs 31.37%, OR = 0.78 [95% CI 0.62 to 0.99]) and the premature birth rate was significantly higher (19.66% vs 28.73%,OR = 1.65 [95% CI 1.05 to 2.59]) in the E supplementation group. Any benefit of oestradiol supplementation for luteal phase support appears to correlate with the serum oestradiol level on the day of hCG trigger. Oestradiol supplementation is beneficial for improving live birth rate in cycles with oestradiol levels less than 5000 pmol/L, but is not recommended in cycles with oestradiol levels over 10 000 pmol/L. © 2018 John Wiley & Sons Ltd.

  9. GPS synchronized power system phase angle measurements

    Science.gov (United States)

    Wilson, Robert E.; Sterlina, Patrick S.

    1994-09-01

    This paper discusses the use of Global Positioning System (GPS) synchronized equipment for the measurement and analysis of key power system quantities. Two GPS synchronized phasor measurement units (PMU) were installed before testing. It was indicated that PMUs recorded the dynamic response of the power system phase angles when the northern California power grid was excited by the artificial short circuits. Power system planning engineers perform detailed computer generated simulations of the dynamic response of the power system to naturally occurring short circuits. The computer simulations use models of transmission lines, transformers, circuit breakers, and other high voltage components. This work will compare computer simulations of the same event with field measurement.

  10. Guidance for the application of an assessment methodology for innovative nuclear energy systems. INPRO manual - Safety of nuclear fuel cycle facilities. Vol. 9 of the final report of phase 1 of the International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO)

    International Nuclear Information System (INIS)

    2008-11-01

    The International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO) was initiated in the year 2000, based on a resolution of the IAEA General Conference (GC(44)/RES/21). The main objectives of INPRO are (1) to help to ensure that nuclear energy is available to contribute in fulfilling energy needs in the 21st century in a sustainable manner, (2) to bring together both technology holders and technology users to consider jointly the international and national actions required to achieve desired innovations in nuclear reactors and fuel cycles; and (3) to create a forum to involve all relevant stakeholders that will have an impact on, draw from, and complement the activities of existing institutions, as well as ongoing initiatives at the national and international level. The INPRO manual is comprised of an overview volume (No. 1), and eight additional volumes covering the areas of economics (Volume 2), infrastructure (Volume 3), waste management (Volume 4), proliferation resistance (Volume 5), physical protection (Volume 6), environment (Volume 7), safety of nuclear reactors (Volume 8), and safety of nuclear fuel cycle facilities (laid out in this report) (Volume 9).This report elaborates on the guidance given in the INPRO report 'Methodology for the assessment of innovative nuclear reactors and fuel cycles', IAEA-TECDOC-1434, and the previous INPRO report 'Guidance for the evaluation for innovative nuclear reactors and fuel cycles', IAEA-TECDOC-1362 (2003), in the area of safety of nuclear reactors. The present version of this manual deals with safety issues related to design and operation of mining, milling, refining, conversion, enrichment, fuel fabrication, fuel storage and fuel reprocessing facilities. The INPRO Manual starts with an introduction in Chapter 1. Chapter 2 sets out the necessary input for an INPRO assessment of the safety of an innovative nuclear fuel cycle facility. This includes information on the design for the plant and the safety

  11. Solution of multiple circuits of steam cycle HTR system

    International Nuclear Information System (INIS)

    Li, Fu; Wang, Dengying; Hao, Chen; Zheng, Yanhua

    2014-01-01

    In order to analyze the dynamic operation performance and safety characteristics of the steam cycle high temperature gas cooled reactor (HTR) systems, it is necessary to find the solution of the whole HTR systems with all coupled circuits, including the primary circuit, the secondary circuit, and the residual heat removal system (RHRS). Considering that those circuits have their own individual fluidity and characteristics, some existing code packages for independent circuits themselves have been developed, for example THEMRIX and TINTE code for the primary circuit of the pebble bed reactor, BLAST for once through steam generator. To solve the coupled steam cycle HTR systems, a feasible way is to develop coupling method to integrate these independent code packages. This paper presents several coupling methods, e.g. the equivalent component method between the primary circuit and steam generator which reflect the close coupling relationship, the overlapping domain decomposition method between the primary circuit and the passive RHRS which reflects the loose coupling relationship. Through this way, the whole steam cycle HTR system with multiple circuits can be easily and efficiently solved by integration of several existing code packages. Based on this methodology, a code package TINTE–BLAST–RHRS was developed. Using this code package, some operation performance of HTR–PM was analyzed, such as the start-up process of the plant, and the depressurized loss of forced cooling accident when different number of residual heat removal trains is operated

  12. Closed Brayton Cycle Power Conversion Unit for Fission Surface Power Phase I Final Report

    Science.gov (United States)

    Fuller, Robert L.

    2010-01-01

    A Closed Brayton cycle power conversion system has been developed to support the NASA fission surface power program. The goal is to provide electricity from a small nuclear reactor heat source for surface power production for lunar and Mars environments. The selected media for a heat source is NaK 78 with water as a cooling source. The closed Brayton cycle power was selected to be 12 kWe output from the generator terminals. A heat source NaK temperature of 850 K plus or minus 25 K was selected. The cold source water was selected at 375 K plus or minus 25 K. A vacuum radiation environment of 200 K is specified for environmental operation. The major components of the system are the power converter, the power controller, and the top level data acquisition and control unit. The power converter with associated sensors resides in the vacuum radiation environment. The power controller and data acquisition system reside in an ambient laboratory environment. Signals and power are supplied across the pressure boundary electrically with hermetic connectors installed on the vacuum vessel. System level analyses were performed on working fluids, cycle design parameters, heater and cooling temperatures, and heat exchanger options that best meet the needs of the power converter specification. The goal is to provide a cost effective system that has high thermal-to-electric efficiency in a compact, lightweight package.

  13. Conceptual design study on advanced aqueous reprocessing system for fast reactor fuel cycle

    International Nuclear Information System (INIS)

    Takata, Takeshi; Koma, Yoshikazu; Sato, Koji; Kamiya, Masayoshi; Shibata, Atsuhiro; Nomura, Kazunori; Ogino, Hideki; Koyama, Tomozo; Aose, Shin-ichi

    2003-01-01

    As a feasibility study on commercialized fast reactor cycle system, a conceptual design study is being progressed for the aqueous and pyrochemical processes from the viewpoint of economical competitiveness, efficient utilization of resources, decreasing environmental impact and proliferation resistance in Japan Nuclear Cycle Development Institute (JNC). In order to meet above-mentioned requirements, the survey on a range of reprocessing technologies and the evaluation of conceptual plant designs against targets for the future fast reactor cycle system have been implemented as the fist phase of the feasibility study. For an aqueous reprocessing process, modification of the conventional PUREX process (a solvent extraction process with purification of U/Pu, with nor recovery of minor actinides (MA)) and investigation of alternatives for the PUREX process has been carried out and design study of advanced aqueous reprocessing system and its alternatives has been conducted. The conceptual design of the advanced aqueous reprocessing system has been updated and evaluated by the latest R and D results of the key technologies such as crystallization, single-cycle extraction, centrifugal contactors, recovery of Am/Cm and waste processing. In this paper, the outline of the design study and the current status of development for advanced aqueous reprocessing system, NEXT process, are mentioned. (author)

  14. Energy systems. Tome 3: advanced cycles, low environmental impact innovative systems; Systeme energetiques, TOME 3: cycles avances, systemes innovants a faible impact environnemental

    Energy Technology Data Exchange (ETDEWEB)

    Gicquel, R

    2009-07-01

    This third tome about energy systems completes the two previous ones by showing up advanced thermodynamical cycles, in particular having a low environmental impact, and by dealing with two other questions linked with the study of systems with a changing regime operation: - the time management of energy, with the use of thermal and pneumatic storage systems and time simulation (schedule for instance) of systems (solar energy type in particular); - the technological dimensioning and non-nominal regime operation studies. Because this last topic is particularly complex, new functionalities have been implemented mainly by using the external classes mechanism, which allows the user to freely personalize his models. This tome is illustrated with about 50 examples of cycles modelled with Thermoptim software. Content: foreword; 1 - generic external classes; 2 - advanced gas turbine cycles; 3 - evaporation-concentration, mechanical steam compression, desalination, hot gas drying; 4 - cryogenic cycles; 5 - electrochemical converters; 6 - global warming, CO{sub 2} capture and sequestration; 7 - future nuclear reactors (coupled to Hirn and Brayton cycles); 8 - thermodynamic solar cycles; 10 - pneumatic and thermal storage; 11 - calculation of thermodynamic solar facilities; 12 - problem of technological dimensioning and non-nominal regime; 13 - exchangers modeling and parameterizing for the dimensioning and the non-nominal regime; 14 - modeling and parameterizing of volumetric compressors; 15 - modeling and parameterizing of turbo-compressors and turbines; 16 - identification methodology of component parameters; 17 - case studies. (J.S.)

  15. Influence of microstructure on low cycle fatigue in some single phase and biphasic stainless steels

    Energy Technology Data Exchange (ETDEWEB)

    Stolarz, J. [Ecole Nationale Superieure des Mines, Centre SMS, URA CNRS 1884, Saint-Etienne (France)

    2004-07-01

    This overview deals with the effects of microstructural parameters in different single phase and biphasic stainless steels on short crack behaviour and on fatigue life in the low cycle regime. The effect of the grain size is investigated in a single phase austenitic stainless steel. Under plastic strain control, the fatigue life increases when the grain size decreases. The results are discussed by analysing the distributions of crack depths as a function of the grain size. The second type of material is a metastable austenitic steel which partially transforms into martensite during LCF at temperatures between -50 C and +120 C. The grain size of the initially single phase austenitic microstructure has a combined influence on the volume fraction of martensite produced during fatigue and on the fatigue life. In this case, the grain size effect is still considerable but totally indirect because all fatigue cracks grow exclusively in the martensite. The cyclic behaviour analysis in biphasic alloys in which two phases undergo plastic deformation during LCF is considerably more complex because the conventional concept of microstructural barriers cannot be applied. The possible damage patterns in a pair of grains with different mechanical properties are discussed on the example of a solution treated and aged superduplex austenitic-ferritic stainless steel (SDSS). The hardening of one phase (ferrite) through ageing at 475 C changes the cyclic behaviour of the initial ''quasi single phase'' microstructure. Consequently, the fatigue life under plastic strain control decreases compared with the solution treated SDSS. The discussion is focussed on LCF damage mechanisms at the microstructure size scale with a particular accent put on the propagation of short cracks in the bulk. All the microstructures exhibit some common features with respect to the behaviour of short cracks. In particular a strong effect of microstructural barriers in the bulk and the

  16. High efficiency Dual-Cycle Conversion System using Kr-85.

    Science.gov (United States)

    Prelas, Mark A; Tchouaso, Modeste Tchakoua

    2018-04-26

    This paper discusses the use of one of the safest isotopes known isotopes, Kr-85, as a candidate fuel source for deep space missions. This isotope comes from 0.286% of fission events. There is a vast quantity of Kr-85 stored in spent fuel and it is continually being produced by nuclear reactors. In using Kr-85 with a novel Dual Cycle Conversion System (DCCS) it is feasible to boost the system efficiency from 26% to 45% over a single cycle device while only increasing the system mass by less than 1%. The Kr-85 isotope is the ideal fuel for a Photon Intermediate Direct Energy Conversion (PIDEC) system. PIDEC is an excellent choice for the top cycle in a DCCS. In the top cycle, ionization and excitation of the Kr-85:Cl gas mixture (99% Kr and 1% Cl) from beta particles creates KrCl* excimer photons which are efficiently absorbed by diamond photovoltaic cells on the walls of the pressure vessels. The benefit of using the DCCS is that Kr-85 is capable of operating at high temperatures in the primary cycle and the residual heat can then be converted into electrical power in the bottom cycle which uses a Stirling Engine. The design of the DCCS begins with a spherical pressure vessel of radius 13.7 cm with 3.7 cm thick walls and is filled with a Kr-85:Cl gas mixture. The inner wall has diamond photovoltaic cells attached to it and there is a sapphire window between the diamond photovoltaic cells and the Kr-85:Cl gas mixture which shields the photovoltaic cells from beta particles. The DCCS without a gamma ray shield has specific power of 6.49 W/kg. A removable 6 cm thick tungsten shield is used to safely limit the radiation exposure levels of personnel. A shadow shield remains in the payload to protect the radiation sensitive components in the flight package. The estimated specific power of the unoptimized system design in this paper is about 2.33 W/kg. The specific power of an optimized system should be higher. The Kr-85 isotope is relatively safe because it

  17. Training effects induced by cycling of magnetic field in ferromagnetic rich phase-separated nanocomposite manganites

    Energy Technology Data Exchange (ETDEWEB)

    Das, Kalipada, E-mail: kalipada.das@saha.ac.in; Das, I.

    2015-12-01

    We have carried out an experimental investigation of magneto-transport and magnetic properties of charge-ordered Pr{sub 0.67}Ca{sub 0.33}MnO{sub 3} (PCMO) and ferromagnetic La{sub 0.67}Sr{sub 0.33}MnO{sub 3} (LSMO) nanoparticles along with a nanocomposite consisting of those two types of nanoparticles. From the magneto-transport measurements, clear irreversibility is observed in the field dependence of resistance due to magnetic field cycling in the case of PCMO nanoparticles. The value of resistance increases during such a field cycling. However such an irreversibility is absent in the case of LSMO nanoparticles as well as nanocomposites. On the other hand, the magnetic measurements indicate the gradual growth of antiferromagnetic phases in all samples leading to a decrease in magnetization. These inconsistencies between magneto-transport and magnetic behaviors are attributed to the magnetic training effects. - Highlights: • The resistance value in Pr{sub 0.67}Ca{sub 0.33}MnO{sub 3} nanoparticles is found to increase owing to the magnetic field cycling. • No anomaly in resistance was found in Pr{sub 0.67}Ca{sub 0.33}MnO{sub 3}–La{sub 0.67}Sr{sub 0.33}MnO{sub 3} nanocomposite. • Magnetic measurements indicate the training effect in nanostructure compounds.

  18. Discovery of fossil lamprey larva from the Lower Cretaceous reveals its three-phased life cycle.

    Science.gov (United States)

    Chang, Mee-mann; Wu, Feixiang; Miao, Desui; Zhang, Jiangyong

    2014-10-28

    Lampreys are one of the two surviving jawless vertebrate groups and one of a few vertebrate groups with the best exemplified metamorphosis during their life cycle, which consists of a long-lasting larval stage, a peculiar metamorphosis, and a relatively short adulthood with a markedly different anatomy. Although the fossil records have revealed that many general features of extant lamprey adults were already formed by the Late Devonian (ca. 360 Ma), little is known about the life cycle of the fossil lampreys because of the lack of fossilized lamprey larvae or transformers. Here we report the first to our knowledge discovery of exceptionally preserved premetamorphic and metamorphosing larvae of the fossil lamprey Mesomyzon mengae from the Lower Cretaceous of Inner Mongolia, China. These fossil ammocoetes look surprisingly modern in having an eel-like body with tiny eyes, oral hood and lower lip, anteriorly positioned branchial region, and a continuous dorsal skin fin fold and in sharing a similar feeding habit, as judged from the detritus left in the gut. In contrast, the larger metamorphosing individuals have slightly enlarged eyes relative to large otic capsules, thickened oral hood or pointed snout, and discernable radials but still anteriorly extended branchial area and lack a suctorial oral disk, which characterize the early stages of the metamorphosis of extant lampreys. Our discovery not only documents the larval conditions of fossil lampreys but also indicates the three-phased life cycle in lampreys emerged essentially in their present mode no later than the Early Cretaceous.

  19. [Morphological changes in the thyroid gland of rats during various phases of the estral cycle].

    Science.gov (United States)

    Pliner, L I; Ledovskaia, S M

    1975-08-01

    The functional state of the thyroid gland and the concentration of thyroid hormones in the peripheral blood were studied in 20 mature female albino rats during their estral cycle. Evaluation of the thyroid functional state was made according to data of histological, morphological (the diameter of folliculi, the height of the thyroid epithelium) and histochemical analysis (determination of NAD and NADP-dehydrogenase, succinatedehydrogenase, lactate dehydrogenase, peroxydase, acid and alkaline phosphatase) as well as biochemical determination of iodine bound with protein (IBP) in the blood plasma and investigation of the ratio of the parameters in question under conditions of the sex cycle. The cyclic changes of the morphological state of the thyroid gland attended by the phases of the estral cycle were revealed. The activation of the organ was observed in proestrus and estrus which was evidenced by high levels of activity of the enzymes under study, high concentration of IBP in the blood and increased height of thyreocytes. A decreased function of the thyroid parenchyma was observed at the period of metaestrus-diestrus.

  20. Terrestrial nitrogen cycling in Earth system models revisited

    Science.gov (United States)

    Stocker, Benjamin D; Prentice, I. Colin; Cornell, Sarah; Davies-Barnard, T; Finzi, Adrien; Franklin, Oskar; Janssens, Ivan; Larmola, Tuula; Manzoni, Stefano; Näsholm, Torgny; Raven, John; Rebel, Karin; Reed, Sasha C.; Vicca, Sara; Wiltshire, Andy; Zaehle, Sönke

    2016-01-01

    Understanding the degree to which nitrogen (N) availability limits land carbon (C) uptake under global environmental change represents an unresolved challenge. First-generation ‘C-only’vegetation models, lacking explicit representations of N cycling,projected a substantial and increasing land C sink under rising atmospheric CO2 concentrations. This prediction was questioned for not taking into account the potentially limiting effect of N availability, which is necessary for plant growth (Hungate et al.,2003). More recent global models include coupled C and N cycles in land ecosystems (C–N models) and are widely assumed to be more realistic. However, inclusion of more processes has not consistently improved their performance in capturing observed responses of the global C cycle (e.g. Wenzel et al., 2014). With the advent of a new generation of global models, including coupled C, N, and phosphorus (P) cycling, model complexity is sure to increase; but model reliability may not, unless greater attention is paid to the correspondence of model process representations ande mpirical evidence. It was in this context that the ‘Nitrogen Cycle Workshop’ at Dartington Hall, Devon, UK was held on 1–5 February 2016. Organized by I. Colin Prentice and Benjamin D. Stocker (Imperial College London, UK), the workshop was funded by the European Research Council,project ‘Earth system Model Bias Reduction and assessing Abrupt Climate change’ (EMBRACE). We gathered empirical ecologists and ecosystem modellers to identify key uncertainties in terrestrial C–N cycling, and to discuss processes that are missing or poorly represented in current models.

  1. Effect of Estradiol Prescribed during Luteal Phase of Art Cycles and Pregnancy Outcome

    Directory of Open Access Journals (Sweden)

    M Karimzadeh

    2007-01-01

    Full Text Available Introduction: Implantation is one of the most important steps in ART cycles and it depends upon embryo and endometrial reception. Different protocols have been suggested for getting better endometrium. It seems estrogen increases the endometrial reception and pregnancy rate by inducing changes in the hormonal status. The aim of this study was to evaluate the effect of estradiol(E2 on luteal phase support and pregnancy rate in ART cycles Methods: This prospective randomized study was done in Yazd at the IVF center from March until December, 2002. 68 patients who had undergone IVF or ICSI were enrolled in the study. Exclusion criteria was age>40, endometriosis and ovarian hyper stimulation syndrome. Induction ovulation protocol was long suppression with GnRH analogues.After embryo transfer, patients were divided in two groups randomly. Both groups received 100mg progesterone IM daily from the transfer day. Estradiol valerate 2 mg/day was added from the 7th transfer day to progesterone in Group I and continued if the BhCG became positive. Abortion and malformations were measured in all patients. Data analyzed with SPSS 11.0 and P value <0.05 considered statistically significant. Results: Pregnancy rate in the 34 patients of estradiol group (group I was 26.5%which was significantly higher than 11.8 %( 4 cases in the other group (Pvalue=0.034. Abortion rate was higher in estradiol group (3 cases, but there was no abortion in the progesterone group(P=0.119. 2 cases of major fetal malformations were observed in E2 supplementation group (P=0.246 . Conclusions: E2 suplementation to progesterone in the luteal phase of ART cycles, especially in the long GnRH analogues causes higher endometrial receptivity and pregnancy rate.

  2. Borrelia burgdorferi requires glycerol for maximum fitness during the tick phase of the enzootic cycle.

    Directory of Open Access Journals (Sweden)

    Christopher J Pappas

    2011-07-01

    Full Text Available Borrelia burgdorferi, the spirochetal agent of Lyme disease, is a vector-borne pathogen that cycles between a mammalian host and tick vector. This complex life cycle requires that the spirochete modulate its gene expression program to facilitate growth and maintenance in these diverse milieus. B. burgdorferi contains an operon that is predicted to encode proteins that would mediate the uptake and conversion of glycerol to dihydroxyacetone phosphate. Previous studies indicated that expression of the operon is elevated at 23°C and is repressed in the presence of the alternative sigma factor RpoS, suggesting that glycerol utilization may play an important role during the tick phase. This possibility was further explored in the current study by expression analysis and mutagenesis of glpD, a gene predicted to encode glycerol 3-phosphate dehydrogenase. Transcript levels for glpD were significantly lower in mouse joints relative to their levels in ticks. Expression of GlpD protein was repressed in an RpoS-dependent manner during growth of spirochetes within dialysis membrane chambers implanted in rat peritoneal cavities. In medium supplemented with glycerol as the principal carbohydrate, wild-type B. burgdorferi grew to a significantly higher cell density than glpD mutant spirochetes during growth in vitro at 25°C. glpD mutant spirochetes were fully infectious in mice by either needle or tick inoculation. In contrast, glpD mutants grew to significantly lower densities than wild-type B. burgdorferi in nymphal ticks and displayed a replication defect in feeding nymphs. The findings suggest that B. burgdorferi undergoes a switch in carbohydrate utilization during the mammal to tick transition. Further, the results demonstrate that the ability to utilize glycerol as a carbohydrate source for glycolysis during the tick phase of the infectious cycle is critical for maximal B. burgdorferi fitness.

  3. Phosphorus cycling in Montreal's food and urban agriculture systems.

    Science.gov (United States)

    Metson, Geneviève S; Bennett, Elena M

    2015-01-01

    Cities are a key system in anthropogenic phosphorus (P) cycling because they concentrate both P demand and waste production. Urban agriculture (UA) has been proposed as a means to improve P management by recycling cities' P-rich waste back into local food production. However, we have a limited understanding of the role UA currently plays in the P cycle of cities or its potential to recycle local P waste. Using existing data combined with surveys of local UA practitioners, we quantified the role of UA in the P cycle of Montreal, Canada to explore the potential for UA to recycle local P waste. We also used existing data to complete a substance flow analysis of P flows in the overall food system of Montreal. In 2012, Montreal imported 3.5 Gg of P in food, of which 2.63 Gg ultimately accumulated in landfills, 0.36 Gg were discharged to local waters, and only 0.09 Gg were recycled through composting. We found that UA is only a small sub-system in the overall P cycle of the city, contributing just 0.44% of the P consumed as food in the city. However, within the UA system, the rate of recycling is high: 73% of inputs applied to soil were from recycled sources. While a Quebec mandate to recycle 100% of all organic waste by 2020 might increase the role of UA in P recycling, the area of land in UA is too small to accommodate all P waste produced on the island. UA may, however, be a valuable pathway to improve urban P sustainability by acting as an activity that changes residents' relationship to, and understanding of, the food system and increases their acceptance of composting.

  4. Supercritical Carbon Dioxide Brayton Cycle Energy Conversion System

    Energy Technology Data Exchange (ETDEWEB)

    Cha, Jae Eun; Kim, S. O.; Seong, S. H.; Eoh, J. H.; Lee, T. H.; Choi, S. K.; Han, J. W.; Bae, S. W

    2007-12-15

    This report contains the description of the S-CO{sub 2} Brayton cycle coupled to KALIMER-600 as an alternative energy conversion system. For system development, a computer code was developed to calculate heat balance of 100% power operation condition. Based on the computer code, the S-CO{sub 2} Brayton cycle energy conversion system was constructed for the KALIMER-600. Using the developed turbomachinery models, the off-design characteristics and the sensitivities of the S-CO{sub 2} turbomachinery were investigated. For the development of PCHE models, a one-dimensional analysis computer code was developed to evaluate the performance of the PCHE. Possible control schemes for power control in the KALIMER-600 S-CO{sub 2} Brayton cycle were investigated by using the MARS code. Simple power reduction and recovery event was selected and analyzed for the transient calculation. For the evaluation of Na/CO{sub 2} boundary failure event, a computer was developed to simulate the complex thermodynamic behaviors coupled with the chemical reaction between liquid sodium and CO{sub 2} gas. The long term behavior of a Na/CO{sub 2} boundary failure event and its consequences which lead to a system pressure transient were evaluated.

  5. Supercritical Carbon Dioxide Brayton Cycle Energy Conversion System

    International Nuclear Information System (INIS)

    Cha, Jae Eun; Kim, S. O.; Seong, S. H.; Eoh, J. H.; Lee, T. H.; Choi, S. K.; Han, J. W.; Bae, S. W.

    2007-12-01

    This report contains the description of the S-CO 2 Brayton cycle coupled to KALIMER-600 as an alternative energy conversion system. For system development, a computer code was developed to calculate heat balance of 100% power operation condition. Based on the computer code, the S-CO 2 Brayton cycle energy conversion system was constructed for the KALIMER-600. Using the developed turbomachinery models, the off-design characteristics and the sensitivities of the S-CO 2 turbomachinery were investigated. For the development of PCHE models, a one-dimensional analysis computer code was developed to evaluate the performance of the PCHE. Possible control schemes for power control in the KALIMER-600 S-CO 2 Brayton cycle were investigated by using the MARS code. Simple power reduction and recovery event was selected and analyzed for the transient calculation. For the evaluation of Na/CO 2 boundary failure event, a computer was developed to simulate the complex thermodynamic behaviors coupled with the chemical reaction between liquid sodium and CO 2 gas. The long term behavior of a Na/CO 2 boundary failure event and its consequences which lead to a system pressure transient were evaluated

  6. Life-Cycle Evaluation of Domestic Energy Systems

    Science.gov (United States)

    Bando, Shigeru; Hihara, Eiji

    Among the growing number of environmental issues, the global warming due to the increasing emission of greenhouse gases, such as carbon dioxide CO2, is the most serious one. In order to reduce CO2 emissions in energy use, it is necessary to reduce primary energy consumption, and to replace energy sources with alternatives that emit less CO2.One option of such ideas is to replace fossil gas for water heating with electricity generated by nuclear power, hydraulic power, and other methods with low CO2 emission. It is also important to use energy efficiently and to reduce waste heat. Co-generation system is one of the applications to be able to use waste heat from a generator as much as possible. The CO2 heat pump water heaters, the polymer electrolyte fuel cells, and the micro gas turbines have high potential for domestic energy systems. In the present study, the life-cycle cost, the life-cycle consumption of primary energy and the life-cycle emission of CO2 of these domestic energy systems are compare. The result shows that the CO2 heat pump water heaters have an ability to reduce CO2 emission by 10%, and the co-generation systems also have another ability to reduce primary energy consumption by 20%.

  7. UTILITY ADVANCED TURBINE SYSTEMS (ATS) TECHNOLOGY READINESS TESTING PHASE 3 RESTRUCTURED (3R)

    Energy Technology Data Exchange (ETDEWEB)

    Unknown

    2000-03-17

    This scope document defines the work scope for accomplishing the design of the GE MS7001H and MS9001H (7H and 9H) combined-cycle power systems under the original ATS Phase 3 DOE Cooperative Agreement No. DE-FC21-95MC31176, and incorporates changes in scope required to convert Phase 3 to the ''restructured'' Phase 3R as defined in Amendment A012 to the Cooperative Agreement.

  8. Enhancing signal detection and completely eliminating scattering using quasi-phase-cycling in 2D IR experiments.

    Science.gov (United States)

    Bloem, Robbert; Garrett-Roe, Sean; Strzalka, Halina; Hamm, Peter; Donaldson, Paul

    2010-12-20

    We demonstrate how quasi-phase-cycling achieved by sub-cycle delay modulation can be used to replace optical chopping in a box-CARS 2D IR experiment in order to enhance the signal size, and, at the same time, completely eliminate any scattering contamination. Two optical devices are described that can be used for this purpose, a wobbling Brewster window and a photoelastic modulator. They are simple to construct, easy to incorporate into any existing 2D IR setup, and have attractive features such as a high optical throughput and a fast modulation frequency needed to phase cycle on a shot-to-shot basis.

  9. A phase plane graph based model of the ovulatory cycle lacking the "positive feedback" phenomenon

    Directory of Open Access Journals (Sweden)

    Kurbel Sven

    2012-08-01

    Full Text Available Abstract When hormones during the ovulatory cycle are shown in phase plane graphs, reported FSH and estrogen values form a specific pattern that resembles the leaning “&" symbol, while LH and progesterone (Pg values form a "boomerang" shape. Graphs in this paper were made using data reported by Stricker et al. [Clin Chem Lab Med 2006;44:883–887]. These patterns were used to construct a simplistic model of the ovulatory cycle without the conventional "positive feedback" phenomenon. The model is based on few well-established relations: hypothalamic GnRH secretion is increased under estrogen exposure during two weeks that start before the ovulatory surge and lasts till lutheolysis. the pituitary GnRH receptors are so prone to downregulation through ligand binding that this must be important for their function. in several estrogen target tissue progesterone receptor (PgR expression depends on previous estrogen binding to functional estrogen receptors (ER, while Pg binding to the expressed PgRs reduces both ER and PgR expression. Some key features of the presented model are here listed: High GnRH secretion induced by the recovered estrogen exposure starts in the late follicular phase and lasts till lutheolysis. The LH and FSH surges start due to combination of accumulated pituitary GnRH receptors and increased GnRH secretion. The surges quickly end due to partial downregulation of the pituitary GnRH receptors (64% reduction of the follicular phase pituitary GnRH receptors is needed to explain the reported LH drop after the surge. A strong increase in the lutheal Pg blood level, despite modest decline in LH levels, is explained as delayed expression of pituitary PgRs. Postponed pituitary PgRs expression enforces a negative feedback loop between Pg levels and LH secretions not before the mid lutheal phase. Lutheolysis is explained as a consequence of Pg binding to hypothalamic and pituitary PgRs that reduces local ER expression. When hypothalamic

  10. Life cycle assessment and the resilience of product systems

    DEFF Research Database (Denmark)

    Pizzol, Massimo

    2015-01-01

    Resilience is the capacity of systems to withstand and recover from disturbance, depends on the structure and architecture of a system, and plays a key role for the sustainability of complex systems. Despite its importance, resilience is not explicitly taken into account by studies of life cycle...... assessment (LCA), which main objective is determining the eco-efficiency of a product system with limited focus on its structure. The question is whether a product system which structure is improved or designed to be more resilient will result in being not only inefficient, but also eco-inefficient, when...... assessed by means of LCA. This study proposes a theoretical modelling approach to compare vulnerable and resilient product systems within the framework of LCA, consisting of assessment of disturbance and system expansion. Examples are provided where the theory is made operational. The structure...

  11. Life cycle assessment of waste management systems: Assessing technical externalities

    DEFF Research Database (Denmark)

    Brogaard, Line Kai-Sørensen

    The life cycle assessment (LCA) of a waste management system relies on many internal characteristics such as pollution control systems and recovery efficiencies. It also relies on technical externalities supporting the waste management system in terms of capital goods and energy and material...... for the primary and secondary production of materials, 366 datasets were gathered. The materials in focus were: paper, newsprint, cardboard, corrugated board, glass, aluminium, steel and plastics (HDPE, LDPE, LLDPE, PET, PS, PVC). Only one quarter of these data concerned secondary production, thus underlining...

  12. Life cycle assessment of domestic heat pump hot water systems in Australia

    Directory of Open Access Journals (Sweden)

    Moore Andrew D.

    2017-01-01

    Full Text Available Water heating accounts for 23% of residential energy consumption in Australia, and, as over half is provided by electric water heaters, is a significant source of greenhouse gas emissions. Due to inclusion in rebate schemes heat pump water heating systems are becoming increasingly popular, but do they result in lower greenhouse gas emissions? This study follows on from a previous life cycle assessment study of domestic hot water systems to include heat pump systems. The streamlined life cycle assessment approach used focused on the use phase of the life cycle, which was found in the previous study to be where the majority of global warming potential (GWP impacts occurred. Data was collected from an Australian heat pump manufacturer and was modelled assuming installation within Australian climate zone 3 (AS/NZS 4234:2011. Several scenarios were investigated for the heat pumps including different sources of electricity (grid, photovoltaic solar modules, and batteries and the use of solar thermal panels. It was found that due to their higher efficiency heat pump hot water systems can result in significantly lower GWP than electric storage hot water systems. Further, solar thermal heat pump systems can have lower GWP than solar electric hot water systems that use conventional electric boosting. Additionally, the contributions of HFC refrigerants to GWP can be significant so the use of alternative refrigerants is recommended. Heat pumps combined with PV and battery technology can achieve the lowest GWP of all domestic hot water systems.

  13. Life cycle assessment of a commercial rainwater harvesting system compared with a municipal water supply system

    Science.gov (United States)

    Building upon previously published life cycle assessment (LCA) methodologies, we conducted an LCA of a commercial rainwater harvesting (RWH) system and compared it to a municipal water supply (MWS) system adapted to Washington, D.C. Eleven life cycle impact assessment (LCIA) indi...

  14. Chemical Engineering Education in a Bologna Three Cycle Degree System

    DEFF Research Database (Denmark)

    Gani, Rafiqul

    For the purpose of harmonization of European higher education, Europe’s education system has been going through major changes under what is commonly known as the ”Bologna Process”. The Bologna declaration in 1999 was the start of the introduction of a three cycle degree system in higher education...... in Europe. To date, many European universities have adopted this degree structure. The Working Party on Education (WPE) of the European Federation of Chemical Engineering (EFCE) carried out research to determine the contents of higher education in chemical engineering (ChE) and related disciplines...... such as applied chemistry and process engineering throughout Europe. The result has been a set of recommendations for the first (BS), second (MS) and third (PhD) cycle chemical engineering education aligned to the Bologna Process. They recommend that students studying towards bachelor and masters qualifications...

  15. Analysis of the functional state of students in the process of healthy training exercises in different phases of the ovarian-menstrual cycle

    Directory of Open Access Journals (Sweden)

    N.V. Petrenko

    2017-11-01

    Full Text Available Aim: to substantiate the application of a rational program of health-training sessions in the educational process of physical education of students in different phases of the ovarian-menstrual cycle. Material: in study participated students (n=127, who did not have deviations in health (the main medical group. According to the results of the tests were determined: heart rate; blood pressure; vital capacity of the lungs. To determine physical performance was used Harvard step-test. Physical exercises from the main means of health fitness were used differentially and dosed. Results: It was established that the consideration in the phases of the ovarian-menstrual cycle of indicators of the functional state, changes in well-being and working capacity give an opportunity: planning loads in the training process; adjustment of volume and intensity of loads. We recommend to schedule the load of our program as follows: in the menstrual phase - the development of flexibility (moderate load; in the postmenstrual phase - development of coordination, overall endurance; in ovulatory - speed development; in postovulatory - development of special endurance; in premenstrual - the development of strength, flexibility. In the postmenstrual and postovulatory phase, a high level of physical working capacity, functional state of the cardiopulmonary system has been registered. It also has a positive effect on body weight correction in the women students. Conclusions: When developing programs of health training sessions with women students it is necessary to take into account the phases of the ovarian-menstrual cycle.

  16. Direct view on the phase evolution in individual LiFePO4 nanoparticles during Li-ion battery cycling

    NARCIS (Netherlands)

    Zhang, X.; Van Hulzen, M.; Singh, D.P.; Brownrigg, A.W.; Wright, J.P.; Van Dijk, N.H.; Wagemaker, M.

    2015-01-01

    Phase transitions in Li-ion electrode materials during (dis)charge are decisive for battery performance, limiting high-rate capabilities and playing a crucial role in the cycle life of Li-ion batteries. However, the difficulty to probe the phase nucleation and growth in individual grains is

  17. Cytokine production by natural killer lymphocytes in follicular and luteal phase of the ovarian cycle in humans

    NARCIS (Netherlands)

    Bouman, A.; Moes, H; Heineman, MJ; De Leij, LFMH; Faas, MM

    PROBLEM: The aim of this study was to test the hypothesis that, during luteal phase of the ovarian cycle, as compared with follicular phase, the cytokine productive capacity of peripheral natural killer (NK)-lymphocytes in humans is shifted towards a "Th2-type"-like response. METHOD OF STUDY:

  18. A novel microalgal system for energy production with nitrogen cycling

    Energy Technology Data Exchange (ETDEWEB)

    Minowa, T.; Sawayama, S. [National Institute for Resources and Environment, Tsukuba (Japan)

    1999-08-01

    A microalga, Chlorella vulgaris, could grow in the recovered solution from the low temperature catalytic gasification of itself, by which methane rich fuel gas was obtained. All nitrogen in the microalga was converted to ammonia during the gasification, and the recovered solution, in which ammonia was dissolved, could be used as nitrogen nutrient. The result of the energy evaluation indicated that the novel microalgal system for energy production with nitrogen cycling could be created. 9 refs., 3 tabs.

  19. Energy recovery system using an organic rankine cycle

    Science.gov (United States)

    Ernst, Timothy C

    2013-10-01

    A thermodynamic system for waste heat recovery, using an organic rankine cycle is provided which employs a single organic heat transferring fluid to recover heat energy from two waste heat streams having differing waste heat temperatures. Separate high and low temperature boilers provide high and low pressure vapor streams that are routed into an integrated turbine assembly having dual turbines mounted on a common shaft. Each turbine is appropriately sized for the pressure ratio of each stream.

  20. Life cycle assessment of hydrogen production and fuel cell systems

    International Nuclear Information System (INIS)

    Dincer, I.

    2007-01-01

    This paper details life cycle assessment (LCA) of hydrogen production and fuel cell system. LCA is a key tool in hydrogen and fuel cell technologies for design, analysis, development; manufacture, applications etc. Energy efficiencies and greenhouse gases and air pollution emissions have been evaluated in all process steps including crude oil and natural gas pipeline transportation, crude oil distillation, natural gas reprocessing, wind and solar electricity generation , hydrogen production through water electrolysis and gasoline and hydrogen distribution and utilization

  1. Nutrient cycle benchmarks for earth system land model

    Science.gov (United States)

    Zhu, Q.; Riley, W. J.; Tang, J.; Zhao, L.

    2017-12-01

    Projecting future biosphere-climate feedbacks using Earth system models (ESMs) relies heavily on robust modeling of land surface carbon dynamics. More importantly, soil nutrient (particularly, nitrogen (N) and phosphorus (P)) dynamics strongly modulate carbon dynamics, such as plant sequestration of atmospheric CO2. Prevailing ESM land models all consider nitrogen as a potentially limiting nutrient, and several consider phosphorus. However, including nutrient cycle processes in ESM land models potentially introduces large uncertainties that could be identified and addressed by improved observational constraints. We describe the development of two nutrient cycle benchmarks for ESM land models: (1) nutrient partitioning between plants and soil microbes inferred from 15N and 33P tracers studies and (2) nutrient limitation effects on carbon cycle informed by long-term fertilization experiments. We used these benchmarks to evaluate critical hypotheses regarding nutrient cycling and their representation in ESMs. We found that a mechanistic representation of plant-microbe nutrient competition based on relevant functional traits best reproduced observed plant-microbe nutrient partitioning. We also found that for multiple-nutrient models (i.e., N and P), application of Liebig's law of the minimum is often inaccurate. Rather, the Multiple Nutrient Limitation (MNL) concept better reproduces observed carbon-nutrient interactions.

  2. Life-cycle air emissions from PV power systems

    International Nuclear Information System (INIS)

    Watt, M.E.; Johnson, A.J.; Outhred, H.R.; Ellis, M.

    1998-01-01

    This paper addresses the air emission of grid supply versus grid-connected and off-grid photovoltaic power generation, using the framework of life-cycle assessment, in the contents of rural household energy supply in Australia. Emissions of carbon dioxide, sulphur dioxde and nitrous oxides are calculated for the three life-cycle stages of manufacture, use and disposal. Sensitivities to materials and data inputs, as well as to component efficiencies, lifetimes and sizing are discussed. For each supply option, demand management options, including insulation and appliance choice, and the substitution of solar heating or bottled gas for electricity are considered. The best option in all cases, in terms of life-cycle air emissions, is a grid-connected photovoltaic system used to supply an energy-efficient household with a mix of solar, gas and electric appliances. However, in financial terms, with current Australian energy prices, this option represents a high capital and life-cycle costs. Additionally, for the grid options, electricity costs do not significantly disadvantage the high demand scenarios. Both results provide a clear illustration of current Australian energy-pricing policies being in conflict with long-term environmental sustainability. (Author)

  3. Reliability and availability requirements analysis for DEMO: fuel cycle system

    International Nuclear Information System (INIS)

    Pinna, T.; Borgognoni, F.

    2015-01-01

    The Demonstration Power Plant (DEMO) will be a fusion reactor prototype designed to demonstrate the capability to produce electrical power in a commercially acceptable way. Two of the key elements of the engineering development of the DEMO reactor are the definitions of reliability and availability requirements (or targets). The availability target for a hypothesized Fuel Cycle has been analysed as a test case. The analysis has been done on the basis of the experience gained in operating existing tokamak fusion reactors and developing the ITER design. Plant Breakdown Structure (PBS) and Functional Breakdown Structure (FBS) related to the DEMO Fuel Cycle and correlations between PBS and FBS have been identified. At first, a set of availability targets has been allocated to the various systems on the basis of their operating, protection and safety functions. 75% and 85% of availability has been allocated to the operating functions of fuelling system and tritium plant respectively. 99% of availability has been allocated to the overall systems in executing their safety functions. The chances of the systems to achieve the allocated targets have then been investigated through a Failure Mode and Effect Analysis and Reliability Block Diagram analysis. The following results have been obtained: 1) the target of 75% for the operations of the fuelling system looks reasonable, while the target of 85% for the operations of the whole tritium plant should be reduced to 80%, even though all the tritium plant systems can individually reach quite high availability targets, over 90% - 95%; 2) all the DEMO Fuel Cycle systems can reach the target of 99% in accomplishing their safety functions. (authors)

  4. Water cycles in closed ecological systems: effects of atmospheric pressure.

    Science.gov (United States)

    Rygalov, Vadim Y; Fowler, Philip A; Metz, Joannah M; Wheeler, Raymond M; Bucklin, Ray A

    2002-01-01

    In bioregenerative life support systems that use plants to generate food and oxygen, the largest mass flux between the plants and their surrounding environment will be water. This water cycle is a consequence of the continuous change of state (evaporation-condensation) from liquid to gas through the process of transpiration and the need to transfer heat (cool) and dehumidify the plant growth chamber. Evapotranspiration rates for full plant canopies can range from ~1 to 10 L m-2 d-1 (~1 to 10 mm m-2 d-1), with the rates depending primarily on the vapor pressure deficit (VPD) between the leaves and the air inside the plant growth chamber. VPD in turn is dependent on the air temperature, leaf temperature, and current value of relative humidity (RH). Concepts for developing closed plant growth systems, such as greenhouses for Mars, have been discussed for many years and the feasibility of such systems will depend on the overall system costs and reliability. One approach for reducing system costs would be to reduce the operating pressure within the greenhouse to reduce structural mass and gas leakage. But managing plant growth environments at low pressures (e.g., controlling humidity and heat exchange) may be difficult, and the effects of low-pressure environments on plant growth and system water cycling need further study. We present experimental evidence to show that water saturation pressures in air under isothermal conditions are only slightly affected by total pressure, but the overall water flux from evaporating surfaces can increase as pressure decreases. Mathematical models describing these observations are presented, along with discussion of the importance for considering "water cycles" in closed bioregenerative life support systems.

  5. Water cycles in closed ecological systems: effects of atmospheric pressure

    Science.gov (United States)

    Rygalov, Vadim Y.; Fowler, Philip A.; Metz, Joannah M.; Wheeler, Raymond M.; Bucklin, Ray A.; Sager, J. C. (Principal Investigator)

    2002-01-01

    In bioregenerative life support systems that use plants to generate food and oxygen, the largest mass flux between the plants and their surrounding environment will be water. This water cycle is a consequence of the continuous change of state (evaporation-condensation) from liquid to gas through the process of transpiration and the need to transfer heat (cool) and dehumidify the plant growth chamber. Evapotranspiration rates for full plant canopies can range from 1 to 10 L m-2 d-1 (1 to 10 mm m-2 d-1), with the rates depending primarily on the vapor pressure deficit (VPD) between the leaves and the air inside the plant growth chamber. VPD in turn is dependent on the air temperature, leaf temperature, and current value of relative humidity (RH). Concepts for developing closed plant growth systems, such as greenhouses for Mars, have been discussed for many years and the feasibility of such systems will depend on the overall system costs and reliability. One approach for reducing system costs would be to reduce the operating pressure within the greenhouse to reduce structural mass and gas leakage. But managing plant growth environments at low pressures (e.g., controlling humidity and heat exchange) may be difficult, and the effects of low-pressure environments on plant growth and system water cycling need further study. We present experimental evidence to show that water saturation pressures in air under isothermal conditions are only slightly affected by total pressure, but the overall water flux from evaporating surfaces can increase as pressure decreases. Mathematical models describing these observations are presented, along with discussion of the importance for considering "water cycles" in closed bioregenerative life support systems.

  6. Implementation of a Cost-Accounting System for Visibility of Weapon Systems Life-Cycle Costs

    National Research Council Canada - National Science Library

    Ugone, Mary

    2001-01-01

    .... The DoD Acquisition Reform Goal 10 required DoD to define requirements and establish an implementation plan for a cost-accounting system that provides routine visibility into weapon system life-cycle...

  7. The VIP/VPACR system in the reproductive cycle of male lizard Podarcis sicula.

    Science.gov (United States)

    Agnese, Marisa; Rosati, Luigi; Prisco, Marina; Coraggio, Francesca; Valiante, Salvatore; Scudiero, Rosaria; Laforgia, Vincenza; Andreuccetti, Piero

    2014-09-01

    Starting from the knowledge that in the reproductive period the Vasoactive Intestinal Peptide (VIP) is widely distributed in Podarcis sicula testis, we studied VIP expression and the localization of the neuropeptide and its receptors in the testis of the Italian wall lizard P. sicula in the other phases of its reproductive cycle (summer stasis, autumnal resumption, winter stasis, spring resumption). By Real Time-PCR, we demonstrated that testicular VIP mRNA levels change during the reproductive cycle, showing a cyclic trend with two peaks, one in the mid-autumnal resumption and the other in the reproductive period. By in situ hybridization and immunohistochemistry, we demonstrated that both VIP mRNA and protein were widely distributed in the testis in almost all the phases of the cycle, except in the early autumnal resumption. As regards the receptors, the VPAC1R was localized mainly in Leydig cells, while the VPAC2R showed the same distribution of VIP. Our results demonstrate that, differently from mammals, where VIP is present only in nerve fibres innerving the testis, an endotesticular synthesis takes place in the lizard and the VIP synthesis changes throughout the reproductive cycle. Moreover, the VIP/VPAC receptor system distribution observed in germ and somatic cells in various phases of the cycle, and particularly in the autumnal resumption and the reproductive period, strongly suggests its involvement in both spermatogenesis and steroidogenesis. Finally, the wider distribution of VIP in lizards with respect to mammals leads us to hypothesize that during the evolution the synthesis sites have been transferred from the testis to other districts, such as the brain. Copyright © 2014 Elsevier Inc. All rights reserved.

  8. Heat treatments and thermomechanical cycling influences on the R-phase in Ti-Ni shape memory alloys

    Directory of Open Access Journals (Sweden)

    Cezar Henrique Gonzalez

    2010-09-01

    Full Text Available This article studies changes observed on the R-phase thermoelastic behavior in a near-equiatomic Ti-Ni shape memory alloy. Three kinds of procedures have been performed: different treatments, thermomechanical cycling under constant loading in shape memory helical springs and thermal cycling in as-treated and trained samples. Several heat treatments were carried out to investigate evolution of the R-phase by differential scanning calorimetry (DSC. A heat treatment was chosen on which R-phase is absent. Shape memory springs were produced and submitted to a training process in an apparatus by tensioning the springs under constant loading. Thermal cycling in DSC was realized in as-treated and trained samples. Several aspects of one-step (B2→B19' and two-steps (B2→R→B19' martensitic transformations and R-phase formation and their evolution during tests were observed and discussed.

  9. Cell cycle G2/M arrest through an S phase-dependent mechanism by HIV-1 viral protein R.

    Science.gov (United States)

    Li, Ge; Park, Hyeon U; Liang, Dong; Zhao, Richard Y

    2010-07-07

    Cell cycle G2 arrest induced by HIV-1 Vpr is thought to benefit viral proliferation by providing an optimized cellular environment for viral replication and by skipping host immune responses. Even though Vpr-induced G2 arrest has been studied extensively, how Vpr triggers G2 arrest remains elusive. To examine this initiation event, we measured the Vpr effect over a single cell cycle. We found that even though Vpr stops the cell cycle at the G2/M phase, but the initiation event actually occurs in the S phase of the cell cycle. Specifically, Vpr triggers activation of Chk1 through Ser345 phosphorylation in an S phase-dependent manner. The S phase-dependent requirement of Chk1-Ser345 phosphorylation by Vpr was confirmed by siRNA gene silencing and site-directed mutagenesis. Moreover, downregulation of DNA replication licensing factors Cdt1 by siRNA significantly reduced Vpr-induced Chk1-Ser345 phosphorylation and G2 arrest. Even though hydroxyurea (HU) and ultraviolet light (UV) also induce Chk1-Ser345 phosphorylation in S phase under the same conditions, neither HU nor UV-treated cells were able to pass through S phase, whereas vpr-expressing cells completed S phase and stopped at the G2/M boundary. Furthermore, unlike HU/UV, Vpr promotes Chk1- and proteasome-mediated protein degradations of Cdc25B/C for G2 induction; in contrast, Vpr had little or no effect on Cdc25A protein degradation normally mediated by HU/UV. These data suggest that Vpr induces cell cycle G2 arrest through a unique molecular mechanism that regulates host cell cycle regulation in an S-phase dependent fashion.

  10. Cell cycle G2/M arrest through an S phase-dependent mechanism by HIV-1 viral protein R

    Directory of Open Access Journals (Sweden)

    Liang Dong

    2010-07-01

    Full Text Available Abstract Background Cell cycle G2 arrest induced by HIV-1 Vpr is thought to benefit viral proliferation by providing an optimized cellular environment for viral replication and by skipping host immune responses. Even though Vpr-induced G2 arrest has been studied extensively, how Vpr triggers G2 arrest remains elusive. Results To examine this initiation event, we measured the Vpr effect over a single cell cycle. We found that even though Vpr stops the cell cycle at the G2/M phase, but the initiation event actually occurs in the S phase of the cell cycle. Specifically, Vpr triggers activation of Chk1 through Ser345 phosphorylation in an S phase-dependent manner. The S phase-dependent requirement of Chk1-Ser345 phosphorylation by Vpr was confirmed by siRNA gene silencing and site-directed mutagenesis. Moreover, downregulation of DNA replication licensing factors Cdt1 by siRNA significantly reduced Vpr-induced Chk1-Ser345 phosphorylation and G2 arrest. Even though hydroxyurea (HU and ultraviolet light (UV also induce Chk1-Ser345 phosphorylation in S phase under the same conditions, neither HU nor UV-treated cells were able to pass through S phase, whereas vpr-expressing cells completed S phase and stopped at the G2/M boundary. Furthermore, unlike HU/UV, Vpr promotes Chk1- and proteasome-mediated protein degradations of Cdc25B/C for G2 induction; in contrast, Vpr had little or no effect on Cdc25A protein degradation normally mediated by HU/UV. Conclusions These data suggest that Vpr induces cell cycle G2 arrest through a unique molecular mechanism that regulates host cell cycle regulation in an S-phase dependent fashion.

  11. Phase transition signals of finite systems

    International Nuclear Information System (INIS)

    Duflot-Flandrois, Veronique

    2001-01-01

    Phase transitions are universal properties of interacting matter. They are well described if the considered system is infinite, by using standard thermodynamics. But in the case of small systems like atomic nuclei, this formalism cannot be applied anymore. Our aim is to propose a statistical mechanics approach in order to define the thermodynamical features of small open systems subject to non-saturating forces. We concentrate in particular on the definition and characterization for such systems of phase transitions belonging to the liquid gas universality class. Theoretical and experimental observables are defined to signal the occurrence and the order of this transition without any ambiguity. One of the most relevant and experimentally accessible observables consists in the study of kinetic energy fluctuations for a fixed value of the total deposited energy. In a first order phase transition such fluctuations become anomaly high and at the same time the size distribution appears to behave critically. All our results are obtained within numerical simulations of the lattice gas model with a nearest neighbors attractive interaction. Finally we check the influence of non-saturating forces, developing the specific example of the Coulomb interaction in the nucleus. Future improvements and perspectives at this work consist in the analysis of specific effects occurring in nuclei: isospin and quantum mechanics. (author) [fr

  12. Theoretical modeling of a gas clearance phase regulation mechanism for a pneumatically-driven split-Stirling-cycle cryocooler

    Science.gov (United States)

    Zhang, Cun-quan; Zhong, Cheng

    2015-03-01

    The concept of a new type of pneumatically-driven split-Stirling-cycle cryocooler with clearance-phase-adjustor is proposed. In this implementation, the gap between the phase-adjusting part and the cylinder of the spring chamber is used, instead of dry friction acting on the pneumatically-driven rod to control motion damping of the displacer and to adjust the phase difference between the compression piston and displacer. It has the advantages of easy damping adjustment, low cost, and simplified manufacturing and assembly. A theoretical model has been established to simulate its dynamic performance. The linear compressor is modeled under adiabatic conditions, and the displacement of the compression piston is experimentally rectified. The working characteristics of the compressor motor and the principal losses of cooling, including regenerator inefficiency loss, solid conduction loss, shuttle loss, pump loss and radiation loss, are taken into account. The displacer motion was modeled as a single-degree-of-freedom (SDOF) forced system. A set of governing equations can be solved numerically to simulate the cooler's performance. The simulation is useful for understanding the physical processes occurring in the cooler and for predicting the cooler's performance.

  13. Monitored Retrievable Storage conceptual system studies: closed-cycle vault

    International Nuclear Information System (INIS)

    Washington, J.A.; Ganley, J.T.

    1984-02-01

    The Nuclear Waste Policy Act of 1982 requires the DOE to submit a proposal to Congress by June 1985 for the construction of one or more Monitored Retrieval Storage (MRS) facilities. In response, the DOE initiated studies to develop system descriptions and cost estimates for preconceptual designs of storage concepts suitable for use at MRS facilities. This report provides a system description and cost estimates for a Closed-Cycle Vault (CCV) MRS facility. The facility description is divided into four parts: (1) the R and H area, (2) the interface facility, (3) the on-site transport system, and (4) the storage system. The MRS facility has been designed to meet handling rates of 1800 and 3000 MTU/yr. The corresponding peak inventories are 15,000 and 72,000 MTU. Three types of cases were considered, based on the material to be stored: (1) Spent fuel only; (2) HLW and TRU waste; and (3) HLW only. For each of these three types, a cost estimate was done for a 15,000 and a 72,000 MTU facility, resulting in six different cost estimates. Section 4 presents the cost analysis of the CCV MRS system. Tables 4-2 through 4-7 give the construction or capital costs for the six cases. Tables 4-8 through 4-13 show the total discounted life-cycle costs for each of the six cases. These life-cycle costs include operating and decommissioning costs. These tables also show the time distribution of the capital costs. Table 2-1 summarizes the capital, operating, and discounted costs for the six cases studied. 2 references, 15 figures, 18 tables

  14. Radioactive waste generated from JAERI partitioning-transmutation cycle system

    Energy Technology Data Exchange (ETDEWEB)

    Shinichi, Nakayama; Yasuji, Morita; Kenji, Nishihara [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan)

    2001-07-01

    Production of lower-level radioactive wastes, as well as the reduction in radioactivity of HLW, is an important performance indicator in assessing the viability of a partitioning-transmutation system. We have begun to identify the chemical compositions and to quantify the amounts of radioactive wastes that may be generated by JAERI processes. Long-lived radionuclides such as {sup 14}C and {sup 59}Ni and spallation products of Pb-Bi coolants are added to the existing inventory of these nuclides that are generated in the current fuel cycle. Spent salts of KCl-LiCl, which is not generated from the current fuel cycle, will be introduced as a waste. (author)

  15. Cycle Trades for Nuclear Thermal Rocket Propulsion Systems

    Science.gov (United States)

    White, C.; Guidos, M.; Greene, W.

    2003-01-01

    Nuclear fission has been used as a reliable source for utility power in the United States for decades. Even in the 1940's, long before the United States had a viable space program, the theoretical benefits of nuclear power as applied to space travel were being explored. These benefits include long-life operation and high performance, particularly in the form of vehicle power density, enabling longer-lasting space missions. The configurations for nuclear rocket systems and chemical rocket systems are similar except that a nuclear rocket utilizes a fission reactor as its heat source. This thermal energy can be utilized directly to heat propellants that are then accelerated through a nozzle to generate thrust or it can be used as part of an electricity generation system. The former approach is Nuclear Thermal Propulsion (NTP) and the latter is Nuclear Electric Propulsion (NEP), which is then used to power thruster technologies such as ion thrusters. This paper will explore a number of indirect-NTP engine cycle configurations using assumed performance constraints and requirements, discuss the advantages and disadvantages of each cycle configuration, and present preliminary performance and size results. This paper is intended to lay the groundwork for future efforts in the development of a practical NTP system or a combined NTP/NEP hybrid system.

  16. Unraveling multiple phases of sulfur cycling during the alteration of ancient ultramafic oceanic lithosphere

    Science.gov (United States)

    Schwarzenbach, Esther M.; Gill, Benjamin C.; Johnston, David T.

    2018-02-01

    Ultramafic-hosted hydrothermal systems - characterized by ongoing serpentinization reactions - exert an important influence on the global sulfur cycle. Extensive water-rock interaction causes elemental exchange between seawater and the oceanic lithosphere, effectively removing sulfate from seawater through both abiogenic and biogenic processes. Here, we use bulk rock multiple sulfur isotope signatures (32S, 33S, 34S) and in situ sulfide analyses together with petrographic observations to track the sulfur cycling processes and the hydrothermal evolution of ancient peridotite-hosted hydrothermal systems. We investigate serpentinized peridotites from the Northern Apennine ophiolite in Italy and the Santa Elena ophiolite in Costa Rica and compare those with the Iberian Margin (Ocean Drilling Program (ODP) Leg 149 and 173) and the 15°20‧N Fracture Zone along the Mid-Atlantic Ridge (ODP Leg 209). In situ measurements of sulfides in the Northern Apennine serpentinites preserve a large range in δ34Ssulfide of -33.8 to +13.3‰ with significant heterogeneities within single sulfide grains and depending on mineralogy. Detailed mineralogical investigation and comparison with bulk rock Δ33Ssulfide and in situ δ34Ssulfide data implies a thermal evolution of the system from high temperatures (∼350 °C) that allowed thermochemical sulfate reduction and input of hydrothermal sulfide to lower temperatures (rock associated with detachment faulting along a mid-ocean ridge spreading center. The Santa Elena peridotites preserve distinct signatures for fluid circulation at high temperatures with both closed system thermochemical sulfate reduction and input of mafic-derived sulfur. In addition, the peridotites provide strong evidence that low Ca2+ concentrations in peridotite-hosted systems can limit sulfate removal during anhydrite precipitation at temperatures above 150 °C. This may play a central role for the availability of sulfate to microbial communities within these

  17. Late phase cell cycle proteins in Alzheimer’s disease: a possible target for therapy?

    KAUST Repository

    Bajic, Vladan

    2017-02-22

    Alzheimer’s disease (AD) is represented by neuronal loss and this loss is correlated to a constant state of neuronal instability induced by intrinsic and extrinsic factors. In this paper data is presented regarding the possible roles of late phase cell cycle proteins in normal and affected neurons with the goal that understanding the mechanisms involved in the regulation of these proteins may represent a novel strategy for AD treatment. The results demonstrate a relative differential pattern of expression of certain proteins (APC/C, Mad1 and Mad2, Bub R1, Bub1, CDK 11, cohesin subunit Rad 21 and astrin) in the AD brain versus age matched controls, and it is suggested that targeting these proteins might translate into potential treatments for AD. Although the data presented here is of some interest, the ability to translate such information into clinical applications is often a challenge.

  18. Late phase cell cycle proteins in Alzheimer’s disease: a possible target for therapy?

    KAUST Repository

    Bajic, Vladan; B. Bajic, Vladimir; Zivkovic, Lada; Arendt, Thomas; Perry, George; Spremo-Potparevic, Biljana

    2017-01-01

    Alzheimer’s disease (AD) is represented by neuronal loss and this loss is correlated to a constant state of neuronal instability induced by intrinsic and extrinsic factors. In this paper data is presented regarding the possible roles of late phase cell cycle proteins in normal and affected neurons with the goal that understanding the mechanisms involved in the regulation of these proteins may represent a novel strategy for AD treatment. The results demonstrate a relative differential pattern of expression of certain proteins (APC/C, Mad1 and Mad2, Bub R1, Bub1, CDK 11, cohesin subunit Rad 21 and astrin) in the AD brain versus age matched controls, and it is suggested that targeting these proteins might translate into potential treatments for AD. Although the data presented here is of some interest, the ability to translate such information into clinical applications is often a challenge.

  19. Integrated operation and management system for a 700MW combined cycle power plant

    Energy Technology Data Exchange (ETDEWEB)

    Shiroumaru, I. (Yanai Power Plant Construction Office, Chugoku Electric Power Co., Inc., 1575-5 Yanai-Miyamoto-Shiohama, Yanai-shi, Yamaguchi-ken (JP)); Iwamiya, T. (Omika Works, Hitachi, Ltd., 5-2-1 Omika-cho, Hitachi-shi, Ibaraki-ken (JP)); Fukai, M. (Hitachi Works, Hitachi, Ltd., 3-1-1 Saiwai-cho, Hitachi-shi, Ibaraki-ken (JP))

    1992-03-01

    Yanai Power Plant of the Chugoku Electric Power Co., Inc. (Yamaguchi Pref., Japan) is in the process of constructing a 1400MW state-of-the-art combined cycle power plant. The first phase, a 350MW power plant, started operation on a commercial basis in November, 1990. This power plant has achieved high efficiency and high operability, major features of a combined cycle power plant. The integrated operation and management system of the power plant takes care of operation, maintenance, control of general business, etc., and was built using the latest computer and digital control and communication technologies. This paper reports that it is expected that this system will enhance efficient operation and management for the power plant.

  20. Demographic-Based Perceptions of Adequacy of Software Security's Presence within Individual Phases of the Software Development Life Cycle

    Science.gov (United States)

    Kramer, Aleksey

    2013-01-01

    The topic of software security has become paramount in information technology (IT) related scholarly research. Researchers have addressed numerous software security topics touching on all phases of the Software Development Life Cycle (SDLC): requirements gathering phase, design phase, development phase, testing phase, and maintenance phase.…

  1. Strategy Diversity Stabilizes Mutualism through Investment Cycles, Phase Polymorphism, and Spatial Bubbles

    Science.gov (United States)

    Boza, Gergely; Kun, Ádám; Scheuring, István; Dieckmann, Ulf

    2012-01-01

    There is continuing interest in understanding factors that facilitate the evolution and stability of cooperation within and between species. Such interactions will often involve plasticity in investment behavior, in response to the interacting partner's investments. Our aim here is to investigate the evolution and stability of reciprocal investment behavior in interspecific interactions, a key phenomenon strongly supported by experimental observations. In particular, we present a comprehensive analysis of a continuous reciprocal investment game between mutualists, both in well-mixed and spatially structured populations, and we demonstrate a series of novel mechanisms for maintaining interspecific mutualism. We demonstrate that mutualistic partners invariably follow investment cycles, during which mutualism first increases, before both partners eventually reduce their investments to zero, so that these cycles always conclude with full defection. We show that the key mechanism for stabilizing mutualism is phase polymorphism along the investment cycle. Although mutualistic partners perpetually change their strategies, the community-level distribution of investment levels becomes stationary. In spatially structured populations, the maintenance of polymorphism is further facilitated by dynamic mosaic structures, in which mutualistic partners form expanding and collapsing spatial bubbles or clusters. Additionally, we reveal strategy-diversity thresholds, both for well-mixed and spatially structured mutualistic communities, and discuss factors for meeting these thresholds, and thus maintaining mutualism. Our results demonstrate that interspecific mutualism, when considered as plastic investment behavior, can be unstable, and, in agreement with empirical observations, may involve a polymorphism of investment levels, varying both in space and in time. Identifying the mechanisms maintaining such polymorphism, and hence mutualism in natural communities, provides a significant

  2. Effect of normal and tumor factors on different phases of cell populations cycle.

    Science.gov (United States)

    Inda, A M; García, A L; Errecalde, A L; Badrán, A F

    1999-12-01

    In the present experiments we studied the effect of extracts from intact liver (LE), ES2 tumor extract (TE), plasmas from intact mice (PI), and from tumor bearing animals (PT) on different phases of hepatocytes and renocytes cell cycles. C3HS 28-day-old male mice, standardized for periodicity analysis, were injected at 16:00 hours and killed every 4 hours during a circadian cycle at 20:00/04; 00:00/08; 04:00/12; 08:00/16; 12:00/20 and 16:00/24 (time of day/hours post treatment). Colchicine (2 microg/g) was injected 4 hours before killing them. Samples of livers and kidneys were processed for histology and mitotic index determinations. The results were expressed as colchicine arrested metaphases per 1000 nuclei. The TE, LE and PI had a promoting effect on the mitotic activity of hepatocytes during the first 12 hours post treatment. During the subsequent 12 hours, not only these treatments but also the PI had an inhibiting effect on the mitotic activity of the same cell population. Also the TE and the PT had a promoting effect on the mitotic activity of the renocytes during the first 12 hours while the effect of all treatments showed a clear inhibition of the mitotic activity studied during the last 12 hours. Taking into account the time elapsed between the injections and the measurements made in these light-dark synchronized animals, we conclude that the increase in mitotic index observed in those tissues stemmed from a reinitiation of cell-cycle traverse in a subpopulation of G2-arrested, noncycling cells.

  3. System analysis and optimisation of a Kalina split-cycle for waste heat recovery on large marine diesel engines

    DEFF Research Database (Denmark)

    Larsen, Ulrik; Nguyen, Tuong-Van; Knudsen, Thomas

    2014-01-01

    Waste heat recovery systems can produce power from heat without using fuel or emitting CO2, therefore their implementation is becoming increasingly relevant. The Kalina cycle is proposed as an efficient process for this purpose. The main reason for its high efficiency is the non-isothermal phase...... change characteristics of the ammonia-water working fluid. The present study investigates a unique type of Kalina process called the Split-cycle, applied to the exhaust heat recovery from large marine engines. In the Split-cycle, the working fluid concentration can be changed during the evaporation...

  4. Late follicular phase administration of levonorgestrel as an emergency contraceptive changes the secretory pattern of glycodelin in serum and endometrium during the luteal phase of the menstrual cycle.

    Science.gov (United States)

    Durand, Marta; Seppala, Markku; Cravioto, Ma Del Carmen; Koistinen, Hannu; Koistinen, Riitta; González-Macedo, José; Larrea, Fernando

    2005-06-01

    This study examined serum glycodelin concentrations and endometrial expression during the luteal phase following oral administration of levonorgestrel (LNG) at different stages of the ovarian cycle. Thirty women were recruited and allocated into three groups. All groups were studied during two consecutive cycles, a control cycle and the treatment cycle. In the treatment cycle, each woman received two doses of 0.75 mg LNG taken 12 h apart on days 3-4 before the luteinizing hormone (LH) surge (Group 1), at the time of LH rise (Group 2) and 48 h after the rise in LH was detected (Group 3). Serum progesterone (P) and glycodelin were measured daily during the luteal phase, and an endometrial biopsy was taken at day LH +9 for immunohistochemical glycodelin-A staining. In Group 1, serum P levels were significantly lower, serum glycodelin levels rose earlier and endometrial glycodelin-A expression was weaker than in Groups 2 and 3, in which no differences were found between control and treatment cycles. Levonorgestrel taken for emergency contraception (EC) prior to the LH surge alters the luteal phase secretory pattern of glycodelin in serum and endometrium. Based on the potent gamete adhesion inhibitory activity of glycodelin-A, the results may account for the action of LNG in EC in those women who take LNG before the LH surge.

  5. Life cycle integrated thermoeconomic assessment method for energy conversion systems

    International Nuclear Information System (INIS)

    Kanbur, Baris Burak; Xiang, Liming; Dubey, Swapnil; Choo, Fook Hoong; Duan, Fei

    2017-01-01

    Highlights: • A new LCA integrated thermoeconomic approach is presented. • The new unit fuel cost is found 4.8 times higher than the classic method. • The new defined parameter increased the sustainability index by 67.1%. • The case studies are performed for countries with different CO 2 prices. - Abstract: Life cycle assessment (LCA) based thermoeconomic modelling has been applied for the evaluation of energy conversion systems since it provided more comprehensive and applicable assessment criteria. This study proposes an improved thermoeconomic method, named as life cycle integrated thermoeconomic assessment (LCiTA), which combines the LCA based enviroeconomic parameters in the production steps of the system components and fuel with the conventional thermoeconomic method for the energy conversion systems. A micro-cogeneration system is investigated and analyzed with the LCiTA method, the comparative studies show that the unit cost of fuel by using the LCiTA method is 3.8 times higher than the conventional thermoeconomic model. It is also realized that the enviroeconomic parameters during the operation of the system components do not have significant impacts on the system streams since the exergetic parameters are dominant in the thermoeconomic calculations. Moreover, the improved sustainability index is found roundly 67.2% higher than the previously defined sustainability index, suggesting that the enviroeconomic and thermoeconomic parameters decrease the impact of the exergy destruction in the sustainability index definition. To find the feasible operation conditions for the micro-cogeneration system, different assessment strategies are presented. Furthermore, a case study for Singapore is conducted to see the impact of the forecasted carbon dioxide prices on the thermoeconomic performance of the micro-cogeneration system.

  6. Phase diagram of Pr-P system

    International Nuclear Information System (INIS)

    Mironov, K.E.

    1981-01-01

    An area of the Pr-P system, adjoining to the Pr ordinate, is plotted up by the DTA method. Presence of P solid solution in Pr is established. Data on thermal stability of PrP, PrP 2 , PrP 5 and PrP 7 are generalized. The diagram of phase transformations in Pr-P system is plotted up proceeding from the whole complex of the data, presented. A supposition is made on a possible formation of solid solutions between the highest polyphosphide and phosphorus [ru

  7. Simulations of phase transitions in ionic systems

    International Nuclear Information System (INIS)

    Panagiotopoulos, A Z

    2005-01-01

    A review of recent simulation work in the area of phase transitions in ionic systems is presented. The vapour-liquid transition for the restricted primitive model has been studied extensively in the past decade. The critical temperature is now known to excellent accuracy and the critical density to moderate accuracy. There is also strong simulation-based evidence that the model is in the Ising universality class. Discretized lattice versions of the model are reviewed. Other systems covered are size- and charge-asymmetric electrolytes, colloid-salt mixtures, realistic salt models and charged chains. Areas of future research needs are briefly discussed

  8. Nuclear Systems Enhanced Performance Program, Maintenance Cycle Extension in Advanced Light Water Reactor Design

    Energy Technology Data Exchange (ETDEWEB)

    Professor Neill Todreas

    2001-10-01

    A renewed interest in new nuclear power generation in the US has spurred interest in developing advanced reactors with features which will address the public's concerns regarding nuclear generation. However, it is economic performance which will dictate whether any new orders for these plants will materialize. Economic performance is, to a great extent, improved by maximizing the time that the plant is on-line generating electricity relative to the time spent off-line conducting maintenance and refueling. Indeed, the strategy for the advanced light water reactor plant IRIS (International Reactor, Innovative and Secure) is to utilize an eight year operating cycle. This report describes a formalized strategy to address, during the design phase, the maintenance-related barriers to an extended operating cycle. The top-level objective of this investigation was to develop a methodology for injecting component and system maintainability issues into the reactor plant design process to overcome these barriers. A primary goal was to demonstrate the applicability and utility of the methodology in the context of the IRIS design. The first step in meeting the top-level objective was to determine the types of operating cycle length barriers that the IRIS design team is likely to face. Evaluation of previously identified regulatory and investment protection surveillance program barriers preventing a candidate operating PWR from achieving an extended (48 month) cycle was conducted in the context of the IRIS design. From this analysis, 54 known IRIS operating cycle length barriers were identified. The resolution methodology was applied to each of these barriers to generate design solution alternatives for consideration in the IRIS design. The methodology developed has been demonstrated to narrow the design space to feasible design solutions which enable a desired operating cycle length, yet is general enough to have broad applicability. Feedback from the IRIS design team

  9. Life cycle assessments of urban water systems: a comparative analysis of selected peer-reviewed literature.

    Science.gov (United States)

    Loubet, Philippe; Roux, Philippe; Loiseau, Eleonore; Bellon-Maurel, Veronique

    2014-12-15

    Water is a growing concern in cities, and its sustainable management is very complex. Life cycle assessment (LCA) has been increasingly used to assess the environmental impacts of water technologies during the last 20 years. This review aims at compiling all LCA papers related to water technologies, out of which 18 LCA studies deals with whole urban water systems (UWS). A focus is carried out on these 18 case studies which are analyzed according to criteria derived from the four phases of LCA international standards. The results show that whereas the case studies share a common goal, i.e., providing quantitative information to policy makers on the environmental impacts of urban water systems and their forecasting scenarios, they are based on different scopes, resulting in the selection of different functional units and system boundaries. A quantitative comparison of life cycle inventory and life cycle impact assessment data is provided, and the results are discussed. It shows the superiority of information offered by multi-criteria approaches for decision making compared to that derived from mono-criterion. From this review, recommendations on the way to conduct the environmental assessment of urban water systems are given, e.g., the need to provide consistent mass balances in terms of emissions and water flows. Remaining challenges for urban water system LCAs are identified, such as a better consideration of water users and resources and the inclusion of recent LCA developments (territorial approaches and water-related impacts). Copyright © 2014 Elsevier Ltd. All rights reserved.

  10. Development of Information Management System for Plant Life Cycle Management

    International Nuclear Information System (INIS)

    Byon, SuJin; Lee, SangHyun; Kim, WooJoong

    2015-01-01

    The study subjects are S. Korean NPP(Nuclear Power Plant) construction projects. Design, construction, operations companies have different nuclear power plant construction project structures, and each company has its own Information Management System. In this study, the end user developed an Information Management System early in the project, and developed a management structure that systematically integrates and interfaces with information in each lifecycle phase. The main perspective of Information Management is moving from the existent document-centric management to the data-centric management. To do so, we intend to integrate information with interfaces among systems. Integrated information management structure and management system are essential for an effective management of the lifecycle information of nuclear power plants that have a lifespan over as much as 80 years. The concept of integration management adopted by the defence, ocean industries or various PLM solution providers is important. Although the NPP project has application systems in each key lifecycle phase, it is more effective to develop and use PLIMS in consideration of the interface and compatibility of information among systems. As an initial study for development of that integrated information management structure, this study is building the system and has interfaced it with a design-stage system

  11. Development of Information Management System for Plant Life Cycle Management

    Energy Technology Data Exchange (ETDEWEB)

    Byon, SuJin; Lee, SangHyun; Kim, WooJoong [KOREA HYDRO and NUCLEAR POWER CO. LTD, Daejeon (Korea, Republic of)

    2015-10-15

    The study subjects are S. Korean NPP(Nuclear Power Plant) construction projects. Design, construction, operations companies have different nuclear power plant construction project structures, and each company has its own Information Management System. In this study, the end user developed an Information Management System early in the project, and developed a management structure that systematically integrates and interfaces with information in each lifecycle phase. The main perspective of Information Management is moving from the existent document-centric management to the data-centric management. To do so, we intend to integrate information with interfaces among systems. Integrated information management structure and management system are essential for an effective management of the lifecycle information of nuclear power plants that have a lifespan over as much as 80 years. The concept of integration management adopted by the defence, ocean industries or various PLM solution providers is important. Although the NPP project has application systems in each key lifecycle phase, it is more effective to develop and use PLIMS in consideration of the interface and compatibility of information among systems. As an initial study for development of that integrated information management structure, this study is building the system and has interfaced it with a design-stage system.

  12. Generation of Phase-Stable Sub-Cycle Mid-Infrared Pulses from Filamentation in Nitrogen

    Directory of Open Access Journals (Sweden)

    Takao Fuji

    2013-02-01

    Full Text Available Sub-single-cycle pulses in the mid-infrared (MIR region were generated through a laser-induced filament. The fundamental (ω1 and second harmonic (ω2 output of a 30-fs Ti:sapphire amplifier were focused into nitrogen gas and produce phase-stable broadband MIR pulses (ω0 by using a four-wave mixing process (ω1 + ω1 - ω2 → ω0 through filamentation. The spectrum spread from 400 cm-1 to 5500 cm-1, which completely covered the MIR region. The low frequency components were detected by using an electro-optic sampling technique with a gaseous medium. The efficiency of the MIR pulse generation was very sensitive to the delay between the fundamental and second harmonic pulses. It was revealed that the delay dependence of the efficiency came from the interference between two opposite parametric processes, ω1 + ω1 - ω2 → ω0 and ω2 - ω1 - ω1 → ω0. The pulse duration was measured as 6.9 fs with cross-correlation frequency-resolved optical gating by using four-wave mixing in nitrogen. The carrier-envelope phase of the MIR pulse was passively stabilized. The instability was estimated as 154 mrad rms in 2.5 h.

  13. Insulin binding characteristics in canine muscle tissue: effects of the estrous cycle phases

    Directory of Open Access Journals (Sweden)

    Álan G. Pöppl

    Full Text Available Abstract: Hormonal fluctuations during the different estrous cycle are a well-recognized cause of insulin resistance in bitches, and little is known about insulin receptor binding or post-binding defects associated with insulin resistance in dogs. To evaluate insulin binding characteristics in muscle tissue of bitches during the estrous cycle, 17 owned bitches were used in the study (six in anestrus, five in estrus, and six in diestrus. An intravenous glucose tolerance test (IVGTT was performed in all patients by means of injection of 1mL/kg of a glucose 50% solution (500mg/kg, with blood sample collection for glucose determination at 0, 3, 5, 7, 15, 30, 45 and 60 minutes after glucose infusion. Muscle samples, taken after spaying surgery, were immediately frozen in liquid nitrogen and then stored at -80 ºC until the membranes were prepared by sequential centrifugation after being homogenized. For binding studies, membranes were incubated in the presence of 20,000cpm of human 125I-insulin and in increasing concentrations of unlabeled human regular insulin for cold saturation. The IVGTT showed no differences among bitches during the estrous cycle regarding baseline glycemia or glycemic response after glucose infusion. Two insulin binding sites - high-affinity and low-affinity ones - were detected by Scatchard analysis, and significant statistical differences were observed in the dissociation constant (Kd1 and maximum binding capacity (Bmax1 of the high-affinity binding sites. The Kd1 for the anestrus group (6.54±2.77nM/mg of protein was smaller (P<0.001 than for the estrus (28.54±6.94nM/mg of protein and diestrus (15.56±3.88nM/mg of protein groups. Bmax1 in the estrus (0.83±0.42nM/mg of protein and diestrus (1.24±0.24nM/mg of protein groups were also higher (P<0.001 than the values observed in anestrus (0.35±0.06nM/mg of protein. These results indicate modulation of insulin binding characteristics during different phases of the estrous

  14. Combined Cycle Engine Large-Scale Inlet for Mode Transition Experiments: System Identification Rack Hardware Design

    Science.gov (United States)

    Thomas, Randy; Stueber, Thomas J.

    2013-01-01

    The System Identification (SysID) Rack is a real-time hardware-in-the-loop data acquisition (DAQ) and control instrument rack that was designed and built to support inlet testing in the NASA Glenn Research Center 10- by 10-Foot Supersonic Wind Tunnel. This instrument rack is used to support experiments on the Combined-Cycle Engine Large-Scale Inlet for Mode Transition Experiment (CCE? LIMX). The CCE?LIMX is a testbed for an integrated dual flow-path inlet configuration with the two flow paths in an over-and-under arrangement such that the high-speed flow path is located below the lowspeed flow path. The CCE?LIMX includes multiple actuators that are designed to redirect airflow from one flow path to the other; this action is referred to as "inlet mode transition." Multiple phases of experiments have been planned to support research that investigates inlet mode transition: inlet characterization (Phase-1) and system identification (Phase-2). The SysID Rack hardware design met the following requirements to support Phase-1 and Phase-2 experiments: safely and effectively move multiple actuators individually or synchronously; sample and save effector control and position sensor feedback signals; automate control of actuator positioning based on a mode transition schedule; sample and save pressure sensor signals; and perform DAQ and control processes operating at 2.5 KHz. This document describes the hardware components used to build the SysID Rack including their function, specifications, and system interface. Furthermore, provided in this document are a SysID Rack effectors signal list (signal flow); system identification experiment setup; illustrations indicating a typical SysID Rack experiment; and a SysID Rack performance overview for Phase-1 and Phase-2 experiments. The SysID Rack described in this document was a useful tool to meet the project objectives.

  15. Introduction to nuclear supply chain management. In the context of fuel cycle strategy from LWR cycle system to FR cycle system

    International Nuclear Information System (INIS)

    Shiotani, Hiroki; Ono, Kiyoshi; Namba, Takashi; Yasumatsu, Naoto; Heta, Masanori

    2011-01-01

    Supply chain management (SCM) is an important technique to maintain supply and demand balance and to achieve total optimization from upstream to downstream in manufacturers' management. One of the major reasons why SCM receives much attention recently is the trend in production and sales systems from 'Push type' to 'Pull type'. 'Push type' can be restated as 'Make to Stock' (MTS). MTS is a type of supply chain in which the production is not connected to actual demand. On the contrary, 'Pull type' can be restated as 'Make to Order' (MTO) in which the production is connected to actual demand. In this paper, the terminologies and ideas of SCM was introduced into the scenario study to give a fresh perspective for considering LWR cycle to FR cycle transition strategies in Japan. Then, an analytical tool (SCM tool) which has been developed by the authors is used to survey Japanese nuclear energy system in transition with the SCM terminologies and viewpoints. When some of the Japanese nuclear fuel cycle strategies and tools are thought back with the framework of SCM, they tend to treat nuclear fuel cycle system as 'Push type' supply chain in their simulations. For example, a reprocessing plant separates SFs (spent fuels) without considering the actual Pu demand. However, because future reprocessing plants and fuel fabrication plants will act as Pu suppliers (front-end facility) to FR as well as back-end facilities of LWRs, the reasonable plant operation principle can be 'Pull type'. The analysis was conducted by the SCM tool to simulate the behaviors of both MTS and MTO type facilities during the LWR to FR transition period. If there are large uncertainties in the Pu demand or the load factor, etc. of future reprocessing plants, SCM framework is beneficial. Furthermore, the realization of MTO type operation by SCM can reduce the recovered Pu stock in spite of the increase of the SF interim storage. As the result of the investigation on the boundary location of 'Push type

  16. Brayton Isotope Power System. Phase I. (Ground demonstration system) Configuration Control Document (CCD)

    International Nuclear Information System (INIS)

    1976-01-01

    The configuration control document (CCD) defines the BIPS-GDS configuration. The GDS configuration is similar to a conceptual flight system design, referred to as the BIPS-FS, which is discussed in App. I. The BIPS is being developed by ERDA as a 500 to 2000 W(e), 7-y life, space power system utilizing a closed Brayton cycle gas turbine engine to convert thermal energy (from an isotope heat source) to electrical energy at a net efficiency exceeding 25 percent. The CCD relates to Phase I of an ERDA Program to qualify a dynamic system for launch in the early 1980's. Phase I is a 35-month effort to provide an FS conceptual design and GDS design, fabrication, and test. The baseline is a 7-year life, 450-pound, 4800 W(t), 1300 W(e) system which will use two multihundred watt (MHW) isotope heat sources being developed

  17. Different Phases of Earthquake Cycle Reflected in GPS Measured Crustal Deformations along the Andes

    Science.gov (United States)

    Khazaradze, G.; Klotz, J.

    2001-12-01

    The South American Geodynamic Activities (SAGA) project was initiated in 1993 by the GeoForschungsZentrum together with host organizations in Argentina and Chile with the main objective of studying the kinematics and dynamics of present-day deformation processes along the central and southern Andes. Currently the SAGA network consists of 230 geodetic markers spanning more than 2000 km long distance from Peru/Chile border in the north to Cape Horn in the south. The majority of the observed crustal deformation field is relatively homogenous: roughly parallel to the plate convergence direction and decreasing in magnitude away from the deformation front. This pattern is characteristic for the \\textit{inter-seismic} phase of earthquake deformation cycle and can be explained by the elastic strain accumulation due to locking of the thrust interface between the subducting Nazca and the overriding South America plates. However, in addition to the dominant inter-seismic signal, close examination of the observed velocity field also reveals significant spatial and temporal variations, contrary to the commonly used assumption of constant deformation rates. This variation is especially pronounced for the measurements in the vicinity of the 1995 Mw8.0 Antofagasta earthquake (22{° }S-26{° }S). Here, after capturing up to 1 meters of \\textit{co-seismic} displacements associated with this event, the analysis of data obtained during the three following field campaigns (1996-1999), reveals highly time dependent deformation pattern. This can be explained by the decreasing importance of \\textit{post-seismic} effects of the Antofagasta event relative to the increasing dominance of the inter-seismic phase of subduction. Perhaps, even more interesting time dependent observations have been detected in the southern part the SAGA network (38{° }S-43{° }S).Here, after 35 years of the occurrence of the 1960 Mw9.5 Chile earthquake, we still see the continuing post-seismic effects of this

  18. Porcine epidemic diarrhea virus through p53-dependent pathway causes cell cycle arrest in the G0/G1 phase.

    Science.gov (United States)

    Sun, Pei; Wu, Haoyang; Huang, Jiali; Xu, Ying; Yang, Feng; Zhang, Qi; Xu, Xingang

    2018-05-22

    Porcine epidemic diarrhea virus (PEDV), an enteropathogenic Alphacoronavirus, has caused enormous economic losses in the swine industry. p53 protein exists in a wide variety of animal cells, which is involved in cell cycle regulation, apoptosis, cell differentiation and other biological functions. In this study, we investigated the effects of PEDV infection on the cell cycle of Vero cells and p53 activation. The results demonstrated that PEDV infection induces cell cycle arrest at G0/G1 phase in Vero cells, while UV-inactivated PEDV does not cause cell cycle arrest. PEDV infection up-regulates the levels of p21, cdc2, cdk2, cdk4, Cyclin A protein and down-regulates Cyclin E protein. Further research results showed that inhibition of p53 signaling pathway can reverse the cell cycle arrest in G0/G1 phase induced by PEDV infection and cancel out the up-regulation of p21 and corresponding Cyclin/cdk mentioned above. In addition, PEDV infection of the cells synchronized in various stages of cell cycle showed that viral subgenomic RNA and virus titer were higher in the cells released from G0/G1 phase synchronized cells than that in the cells released from the G1/S phase and G2/M phase synchronized or asynchronous cells after 18 h p.i.. This is the first report to demonstrate that the p53-dependent pathway plays an important role in PEDV induced cell cycle arrest and beneficially contributes to viral infection. Copyright © 2018 Elsevier B.V. All rights reserved.

  19. Life cycle assessment of agricultural biogas production systems

    Energy Technology Data Exchange (ETDEWEB)

    Lansche, J.; Muller, J. [Hohenheim Univ., Stuttgart (Germany). Inst. of Agricultural Engineering, Tropical and Subtropical Group

    2010-07-01

    Agricultural activities are large contributors to anthropogenic greenhouse gas emissions. This paper discussed the effectiveness of reducing agricultural emissions by using liquid manure to produce biogas. When using this technique, greenhouse gas emissions from manure storage are avoided and renewable energy is generated as heat and electricity in combined heat and power plants. The purpose of this study was to evaluate the environmental impacts of biogas production systems based on the methods of life cycle assessment. The traditional use of agricultural manures was compared with conventional energy production. The Gabi 4.3 software was used to create a model to evaluate the biogas production systems according to their environmental impact. In addition to the global warming potential, other impact categories were also used to evaluate the effects of the systems in eutrophication and acidification. It was concluded that environmental benefits can be obtained in terms of greenhouse gas emissions compared to electricity production from biogas with the typical German marginal electricity mix.

  20. Closed Brayton cycle power conversion systems for nuclear reactors :

    Energy Technology Data Exchange (ETDEWEB)

    Wright, Steven A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Lipinski, Ronald J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Vernon, Milton E. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Sanchez, Travis [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2006-04-01

    This report describes the results of a Sandia National Laboratories internally funded research program to study the coupling of nuclear reactors to gas dynamic Brayton power conversion systems. The research focused on developing integrated dynamic system models, fabricating a 10-30 kWe closed loop Brayton cycle, and validating these models by operating the Brayton test-loop. The work tasks were performed in three major areas. First, the system equations and dynamic models for reactors and Closed Brayton Cycle (CBC) systems were developed and implemented in SIMULINKTM. Within this effort, both steady state and dynamic system models for all the components (turbines, compressors, reactors, ducting, alternators, heat exchangers, and space based radiators) were developed and assembled into complete systems for gas cooled reactors, liquid metal reactors, and electrically heated simulators. Various control modules that use proportional-integral-differential (PID) feedback loops for the reactor and the power-conversion shaft speed were also developed and implemented. The simulation code is called RPCSIM (Reactor Power and Control Simulator). In the second task an open cycle commercially available Capstone C30 micro-turbine power generator was modified to provide a small inexpensive closed Brayton cycle test loop called the Sandia Brayton test-Loop (SBL-30). The Capstone gas-turbine unit housing was modified to permit the attachment of an electrical heater and a water cooled chiller to form a closed loop. The Capstone turbine, compressor, and alternator were used without modification. The Capstone systems nominal operating point is 1150 K turbine inlet temperature at 96,000 rpm. The annular recuperator and portions of the Capstone control system (inverter) and starter system also were reused. The rotational speed of the turbo-machinery is controlled by adjusting the alternator load by using the electrical grid as the load bank. The SBL-30 test loop was operated at

  1. S-phase Synchronization Facilitates the Early Progression of Induced-Cardiomyocyte Reprogramming through Enhanced Cell-Cycle Exit.

    Science.gov (United States)

    Bektik, Emre; Dennis, Adrienne; Pawlowski, Gary; Zhou, Chen; Maleski, Danielle; Takahashi, Satoru; Laurita, Kenneth R; Deschênes, Isabelle; Fu, Ji-Dong

    2018-05-04

    Direct reprogramming of fibroblasts into induced cardiomyocytes (iCMs) holds a great promise for regenerative medicine and has been studied in several major directions. However, cell-cycle regulation, a fundamental biological process, has not been investigated during iCM-reprogramming. Here, our time-lapse imaging on iCMs, reprogrammed by Gata4, Mef2c, and Tbx5 (GMT) monocistronic retroviruses, revealed that iCM-reprogramming was majorly initiated at late-G1- or S-phase and nearly half of GMT-reprogrammed iCMs divided soon after reprogramming. iCMs exited cell cycle along the process of reprogramming with decreased percentage of 5-ethynyl-20-deoxyuridine (EdU)⁺/α-myosin heavy chain (αMHC)-GFP⁺ cells. S-phase synchronization post-GMT-infection could enhance cell-cycle exit of reprogrammed iCMs and yield more GFP high iCMs, which achieved an advanced reprogramming with more expression of cardiac genes than GFP low cells. However, S-phase synchronization did not enhance the reprogramming with a polycistronic-viral vector, in which cell-cycle exit had been accelerated. In conclusion, post-infection synchronization of S-phase facilitated the early progression of GMT-reprogramming through a mechanism of enhanced cell-cycle exit.

  2. Development of the System Dynamics Code using Homogeneous Equilibrium Model for S-CO{sub 2} Brayton cycle Transient Analyses

    Energy Technology Data Exchange (ETDEWEB)

    Bae, Seong Jun; Lee, Won Woong; Oh, Bongseong; Lee, Jeong Ik [KAIST, Daejeon (Korea, Republic of)

    2016-10-15

    The features of the S-CO{sub 2} Brayton cycle come from a small compressing work by designing the compressor inlet close the critical point of CO{sub 2}. This means the system condition can be operating under two-phase or sub-critical phase during transient situations such as changes of cooling system performance, load variations, etc. Since there is no operating MW scale S-CO{sub 2} Brayton cycle system in the world yet, using an analytical code is the only way to predict the system behavior and develop operating strategies of the S-CO{sub 2} Brayton cycles. Therefore, the development of a credible system code is an important part for the practical S-CO{sub 2} system research. The current status of the developed system analysis code for S-CO{sub 2} Brayton cycle transient analyses in KAIST and verification results are presented in this paper. To avoid errors related with convergences of the code during the phase changing flow calculation in GAMMA+ code, the authors have developed a system analysis code using Homogeneous Equilibrium Model (HEM) for the S-CO{sub 2} Brayton cycle transient analysis. The backbone of the in-house code is the GAMMA+1.0 code, but treating the quality of fluid by tracking system enthalpy gradient every time step. Thus, the code adopts pressure and enthalpy as the independent scalar variables to track the system enthalpy for updating the quality of the system every time step. The heat conduction solving method, heat transfer correlation and frictional losses on the pipe are referred from the GAMMA+ code.

  3. Association between different phases of menstrual cycle and body image measures of perceived size, ideal size, and body dissatisfaction.

    Science.gov (United States)

    Teixeira, André Luiz S; Dias, Marcelo Ricardo C; Damasceno, Vinícius O; Lamounier, Joel A; Gardner, Rick M

    2013-12-01

    The association between phases of the menstrual cycle and body image was investigated. 44 university women (M age = 23.3 yr., SD = 4.7) judged their perceived and ideal body size, and body dissatisfaction was calculated at each phase of the menstrual cycle, including premenstrual, menstrual, and intermenstrual. Participants selected one of nine figural drawings ranging from very thin to obese that represented their perceived size and ideal size. Body dissatisfaction was measured as the absolute difference between scores on perceived and ideal figural drawings. During each menstrual phase, anthropometric measures of weight, height, body mass index, circumference of waist and abdomen, and body composition were taken. There were no significant differences in any anthropometric measures between the three menstrual cycle phases. Perceived body size and body dissatisfaction were significantly different between menstrual phases, with the largest perceived body size and highest body dissatisfaction occurring during the menstrual phase. Ideal body size did not differ between menstrual phases, although participants desired a significantly smaller ideal size as compared to the perceived size.

  4. Integrated manure utilization system life-cycle value assessment

    Energy Technology Data Exchange (ETDEWEB)

    Row, J.; Neabel, D. [Pembina Inst. for Appropriate Development, Drayton Valley, AB (Canada)

    2005-10-15

    A life-cycle assessment of the Alberta Research Council (ARC) and Highmark Renewables' development of an integrated manure utilization system (IMUS) were presented. The assessment focused on an evaluation of factors of primary importance to government, investors and the livestock industry. IMUS technology uses manure as a resource to produce electricity, heat, bio-based fertilizer and reusable water. Results of the assessment indicated that IMUS plants have the potential to be financially viable if a power purchase of $90 MWh on average can be purchased from a 30,000 head livestock operation. A capital cost of under $11 million is necessary, and an established biofertilizer price of $50 per tonne should be established. An IMUS plant was estimated to reduce life-cycle greenhouse gas emissions by 70 to 80 per cent when compared to land spreading. Reductions are accomplished through displacing electricity from the provincial grid and reducing nitrous oxide (N{sub 2}O) emissions from spreading of manure The IMUS plants lessen environment impacts by reducing the extraction and consumption of non-renewable resources, and by displacing an estimated 11,700 GJ of coal and natural gas per 1000 head of cattle per year. In addition, various pathogens within manure are eliminated. The plants have the potential to eliminate the environmental hazards associated with the disposal of deadstock. The systems reduce manure odour, lessen truck traffic and are expected to contribute to rural economic diversification. Barriers to further implementation of IMUS were discussed, as well as emerging opportunities for IMUS developers. It was concluded that the initial assessments of the IMUS were positive. Further investigation is needed to determine actual life-cycle performance of the operations. 18 refs., 3 tabs., 3 figs.

  5. Women's preferences for men's beards show no relation to their ovarian cycle phase and sex hormone levels.

    Science.gov (United States)

    Dixson, Barnaby J W; Lee, Anthony J; Blake, Khandis R; Jasienska, Grazyna; Marcinkowska, Urszula M

    2018-01-01

    According to the ovulatory shift hypothesis, women's mate preferences for male morphology indicative of competitive ability, social dominance, and/or underlying health are strongest at the peri-ovulatory phase of the menstrual cycle. However, recent meta-analyses are divided on the robustness of such effects and the validity of the often-used indirect estimates of fertility and ovulation has been called into question in methodological studies. In the current study, we test whether women's preferences for men's beardedness, a cue of male sexual maturity, androgenic development and social dominance, are stronger at the peri-ovulatory phase of the menstrual cycle compared to during the early follicular or the luteal phase. We also tested whether levels of estradiol, progesterone, and the estradiol to progesterone ratio at each phase were associated with facial hair preferences. Fifty-two heterosexual women completed a two-alternative forced choice preference test for clean-shaven and bearded male faces during the follicular, peri-ovulatory (validated by the surge in luteinizing hormone or the drop in estradiol levels) and luteal phases. Participants also provided for one entire menstrual cycle daily saliva samples for subsequent assaying of estradiol and progesterone. Results showed an overall preference for bearded over clean-shaven faces at each phase of the menstrual cycle. However, preferences for facial hair were not significantly different over the phases of menstrual cycle and were not significantly associated with levels of reproductive hormones. We conclude that women's preferences for men's beardedness may not be related to changes in their likelihood of conception. Copyright © 2017 Elsevier Inc. All rights reserved.

  6. Influence of accelerated thermal charging and discharging cycles on thermo-physical properties of organic phase change materials for solar thermal energy storage applications

    International Nuclear Information System (INIS)

    Raam Dheep, G.; Sreekumar, A.

    2015-01-01

    Highlights: • Identification of organic phase change materials namely benzamide and sebacic acid. • Thermal reliability studies on identified phase change materials. • Measurement of phase transition temperature and latent heat of fusion. • Analysis of relative percentage difference (RPD%) in heat of fusion and melting temperature of benzamide and sebacic acid. - Abstract: Integration of appropriate thermal energy storage system plays a predominant role in upgrading the efficiency of solar thermal energy devices by reducing the incongruity between energy supply and demand. Latent heat thermal energy storage based on phase change materials (PCM) is found to be the most efficient and prospective method for storage of solar thermal energy. Ensuring the thermal reliability of PCM through large number of charging (melting) and discharging (solidification) cycles is a primary prerequisite to determine the suitability of PCM for a specific thermal energy storage applications. The present study explains the experimental analysis carried out on two PCM’s namely benzamide and sebacic acid to check the compatibility of the material in solar thermal energy storage applications. The selected materials were subjected to one thousand accelerated melting and solidification cycles in order to investigate the percentage of variation at different stages on latent heat of fusion, phase transition temperature, onset and peak melting temperature. Differential Scanning Calorimeter (DSC) was used to determine the phase transition temperature and heat of fusion upon completion of every 100 thermal cycles and continued up to 1000 cycles. Relative Percentage Difference (RPD%) is calculated to find out the absolute deviation of melting temperature and latent heat of fusion with respect to zeroth cycle. The experimental study recorded a melting temperatures of benzamide and sebacic acid as 125.09 °C and 135.92 °C with latent heat of fusion of 285.1 (J/g) and 374.4 (J/g). The

  7. Effects of menstrual cycle phase and oral contraceptives on alertness, cognitive performance, and circadian rhythms during sleep deprivation

    Science.gov (United States)

    Wright, K. P. Jr; Badia, P.; Czeisler, C. A. (Principal Investigator)

    1999-01-01

    The influence of menstrual cycle phase and oral contraceptive use on neurobehavioral function and circadian rhythms were studied in healthy young women (n = 25) using a modified constant routine procedure during 24 h of sleep deprivation. Alertness and performance worsened across sleep deprivation and also varied with circadian phase. Entrained circadian rhythms of melatonin and body temperature were evident in women regardless of menstrual phase or oral contraceptive use. No significant difference in melatonin levels, duration, or phase was observed between women in the luteal and follicular phases, whereas oral contraceptives appeared to increase melatonin levels. Temperature levels were higher in the luteal phase and in oral contraceptive users compared to women in the follicular phase. Alertness on the maintenance of wakefulness test and some tests of cognitive performance were poorest for women in the follicular phase especially near the circadian trough of body temperature. These observations suggest that hormonal changes associated with the menstrual cycle and the use of oral contraceptives contribute to changes in nighttime waking neurobehavioral function and temperature level whereas these factors do not appear to affect circadian phase.

  8. Change in Water Cycle- Important Issue on Climate Earth System

    Science.gov (United States)

    Singh, Pratik

    Change in Water Cycle- Important Issue on Climate Earth System PRATIK KUMAR SINGH1 1BALDEVRAM MIRDHA INSTITUTE OF TECHNOLOGY,JAIPUR (RAJASTHAN) ,INDIA Water is everywhere on Earth and is the only known substance that can naturally exist as a gas, liquid, and solid within the relatively small range of air temperatures and pressures found at the Earth's surface.Changes in the hydrological cycle as a consequence of climate and land use drivers are expected to play a central role in governing a vast range of environmental impacts.Earth's climate will undergo changes in response to natural variability, including solar variability, and to increasing concentrations of green house gases and aerosols.Further more, agreement is widespread that these changes may profoundly affect atmospheric water vapor concentrations, clouds and precipitation patterns.As we know that ,a warmer climate, directly leading to increased evaporation, may well accelerate the hydrological cycle, resulting in an increase in the amount of moisture circulating through the atmosphere.The Changing Water Cycle programmer will develop an integrated, quantitative understanding of the changes taking place in the global water cycle, involving all components of the earth system, improving predictions for the next few decades of regional precipitation, evapotranspiration, soil moisture, hydrological storage and fluxes.The hydrological cycle involves evaporation, transpiration, condensation, precipitation, and runoff. NASA's Aqua satellite will monitor many aspects of the role of water in the Earth's systems, and will do so at spatial and temporal scales appropriate to foster a more detailed understanding of each of the processes that contribute to the hydrological cycle. These data and the analyses of them will nurture the development and refinement of hydrological process models and a corresponding improvement in regional and global climate models, with a direct anticipated benefit of more accurate weather and

  9. Service water system aging assessment - Phase I

    International Nuclear Information System (INIS)

    Jarrell, D.B.; Zimmerman, P.W.; Gore, M.L.

    1988-01-01

    The Service Water System (SWS) represents the final heat transfer loop between decay heat generated in the nuclear core and the safe dispersal of that heat energy in the environment. It is the objective of this investigation to demonstrate that aging phenomena can be identified and quantified such that aging degradation of system components can be detected and mitigated prior to the reduction of system availability to below an acceptable threshold. The approach used during the Phase I task was to (1) perform a literature search of government and private sector reports which relate to service water, aging related degradation, and potential methodologies for analysis; (2) assemble a data base which contains all the commercial power plants in the US, their Service Water System configuration, characteristics, and water source; (3) obtain and examine the available service water data from large generic data bases, i.e. NPRDS, LER, NPE, inspection reports, and other relevant plant reference data; (4) perform a fault tree analysis of a typical plant service water systems to examine failure propagation and understand specific input requirements of probabilistic risk analyses; (5) develop an in-depth questionnaire protocol for examining the information resource at a power plant which is not available through data base query and visit a central station power plant and solicit the required information; (6) analyze the information obtained from the in-depth plant interrogation and draw contrasts and conclusions with the data base information; (7) utilize the plant information to perform an interim assessment of service water system degradation mechanisms and focus future investigations. This paper addresses the elements of this task plan numbered 1, 3, 6, and 7. The remaining items are detailed in the phase-I report

  10. A comparative life cycle assessment of marine power systems

    International Nuclear Information System (INIS)

    Ling-Chin, Janie; Roskilly, Anthony P.

    2016-01-01

    Highlights: • Correlation among resources, emissions, key components and processes was attained. • Environmental benefits of innovative power systems were verified. • New-build system showed a great advantage over retrofit and conventional systems. • Relative contribution of significant components remained or became more profound. • Influence of fuel consumption quantity over the estimates varied with impact types. - Abstract: Despite growing interest in advanced marine power systems, knowledge gaps existed as it was uncertain which configuration would be more environmentally friendly. Using a conventional system as a reference, the comparative life cycle assessment (LCA) study aimed to compare and verify the environmental benefits of advanced marine power systems i.e. retrofit and new-build systems which incorporated emerging technologies. To estimate the environmental impact attributable to each system, a bottom-up integrated system approach was applied, i.e. LCA models were developed for individual components using GaBi, optimised operational profiles and input data standardised from various sources. The LCA models were assessed using CML2001, ILCD and Eco-Indicator99 methodologies. The estimates for the advanced systems were compared to those of the reference system. The inventory analysis results showed that both retrofit and new-build systems consumed less fuels (8.28% and 29.7% respectively) and released less emissions (5.2–16.6% and 29.7–55.5% respectively) during operation whilst more resources were consumed during manufacture, dismantling and the end of life. For 14 impact categories relevant to global warming, acidification, eutrophication, photochemical ozone creation and PM/respiratory inorganic health issues, reduction in LCIA results was achieved by retrofit (2.7–6.6%) and new-build systems (35.7–50.7%). The LCIA results of the retrofit system increased in ecotoxicity (1–8%), resource depletion (1–2%) and fossil fuel depletion

  11. REQUIREMENTS FOR SYSTEMS DEVELOPMENT LIFE CYCLE MODELS FOR LARGE-SCALE DEFENSE SYSTEMS

    Directory of Open Access Journals (Sweden)

    Kadir Alpaslan DEMIR

    2015-10-01

    Full Text Available TLarge-scale defense system projects are strategic for maintaining and increasing the national defense capability. Therefore, governments spend billions of dollars in the acquisition and development of large-scale defense systems. The scale of defense systems is always increasing and the costs to build them are skyrocketing. Today, defense systems are software intensive and they are either a system of systems or a part of it. Historically, the project performances observed in the development of these systems have been signifi cantly poor when compared to other types of projects. It is obvious that the currently used systems development life cycle models are insuffi cient to address today’s challenges of building these systems. Using a systems development life cycle model that is specifi cally designed for largescale defense system developments and is effective in dealing with today’s and near-future challenges will help to improve project performances. The fi rst step in the development a large-scale defense systems development life cycle model is the identifi cation of requirements for such a model. This paper contributes to the body of literature in the fi eld by providing a set of requirements for system development life cycle models for large-scale defense systems. Furthermore, a research agenda is proposed.

  12. Phasing of Debuncher Stochastic Cooling Transverse Systems

    International Nuclear Information System (INIS)

    Pasquinelli, Ralph

    2000-01-01

    With the higher frequency of the cooling systems in the Debuncher, a modified method of making transfer functions has been developed for transverse systems. (Measuring of the momentum systems is unchanged.) Speed in making the measurements is critical, as the beam tends to decelerate due to vacuum lifetime. In the 4-8 GHz band, the harmonics in the Debuncher are 6,700 to 13,400 times the revolution frequency. Every Hertz change in revolution frequency is multiplied by this harmonic number and becomes a frequency measurement error, which is an appreciable percent of the momentum width of the beam. It was originally thought that a momentum cooling system would be phased first so that the beam could be kept from drifting in revolution frequency. As it turned out, the momentum cooling was so effective (even with the gain turned down) that the momentum width normalized to fo became less than one Hertz on the Schottky pickup. A beam this narrow requires very precise measurement of tune and revolution frequency. It was difficult to get repeatable results. For initial measuring of the transverse arrays, relative phase and delay is all that is required, so the measurement settings outlined below will suffice. Once all input and output arrays are phased, a more precise measurement of all pickups to all kickers can be done with more points and both upper and lower side bands, as in figure 1. Settings on the network analyzer were adjusted for maximum measurement speed. Data is not analyzed until a complete set of measurements is taken. Start and stop frequencies should be chosen to be just slightly wider than the band being measured. For transverse systems, select betatron USB for the measurement type. This will make the measurement two times faster. Select 101 for the number of points, sweep time of 5 seconds, IF bandwidth 30 Hz, averages = 1. It is important during the phasing to continually measure the revolution frequency and beam width of the beam for transverse systems

  13. Structure and sources of solar wind in the growing phase of 24th solar cycle

    Science.gov (United States)

    Slemzin, Vladimir; Goryaev, Farid; Shugay, Julia; Rodkin, Denis; Veselovsky, Igor

    2015-04-01

    We present analysis of the solar wind (SW) structure and its association with coronal sources during the minimum and rising phase of 24th solar cycle (2009-2011). The coronal sources prominent in this period - coronal holes, small areas of open magnetic fields near active regions and transient sources associated with small-scale solar activity have been investigated using EUV solar images and soft X-ray fluxes obtained by the CORONAS-Photon/TESIS/Sphinx, PROBA2/SWAP, Hinode/EIS and AIA/SDO instruments as well as the magnetograms obtained by HMI/SDO. It was found that at solar minimum (2009) velocity and magnetic field strength of high speed wind (HSW) and transient SW from small-scale flares did not differ significantly from those of the background slow speed wind (SSW). The major difference between parameters of different SW components was seen in the ion composition represented by the C6/C5, O7/O6, Fe/O ratios and the mean charge of Fe ions. With growing solar activity, the speed of HSW increased due to transformation of its sources - small-size low-latitude coronal holes into equatorial extensions of large polar holes. At that period, the ion composition of transient SW changed from low-temperature to high-temperature values, which was caused by variation of the source conditions and change of the recombination/ionization rates during passage of the plasma flow through the low corona. However, we conclude that criteria of separation of the SW components based on the ion ratios established earlier by Zhao&Fisk (2009) for higher solar activity are not applicable to the extremely weak beginning of 24th cycle. The research leading to these results has received funding from the European Commission's Seventh Framework Programme (FP7/2007-2013) under the grant agreement eHeroes (project n° 284461, www.eheroes.eu).

  14. Integrated working fluid-thermodynamic cycle design of organic Rankine cycle power systems for waste heat recovery

    DEFF Research Database (Denmark)

    Cignitti, Stefano; Andreasen, Jesper Graa; Haglind, Fredrik

    2017-01-01

    recovery. Inthis paper, an organic Rankine cycle process and its pure working fluid are designed simultaneously forwaste heat recovery of the exhaust gas from a marine diesel engine. This approach can overcome designissues caused by the high sensitivity between the fluid and cycle design variables......Today, some established working fluids are being phased out due to new international regulations on theuse of environmentally harmful substances. With an ever-increasing cost to resources, industry wants toconverge on improved sustainability through resource recovery, and in particular waste heat...

  15. Dynamic Isotope Power System: technology verification phase, program plan, 1 October 1978

    International Nuclear Information System (INIS)

    1979-01-01

    The technology verification phase program plan of the Dynamic Isotope Power System (DIPS) project is presented. DIPS is a project to develop a 0.5 to 2.0 kW power system for spacecraft using an isotope heat source and a closed-cycle Rankine power-system with an organic working fluid. The technology verification phase's purposes are to increase the system efficiency to over 18%, to demonstrate system reliability, and to provide an estimate for flight test scheduling. Progress toward these goals is reported

  16. New photosensitive systems for volume phase holography

    Science.gov (United States)

    Bianco, Andrea; Colella, Letizia; Galli, Paola; Zanutta, Alessio; Bertarelli, Chiara

    2017-05-01

    Volume phase holographic elements are becoming attractive thanks to the large efficiency and good optical quality. They are based on photosensitive materials where a modulation of the refractive index is induced. In this paper, we highlight the strategies to obtain a change in the refractive index in a dielectric material, namely a change in the material density and/or in the molecular polarizability. Moreover, we show the results achieved for materials that undergo the photo-Fries reaction as function of the molecular structure and the illumination conditions. We also report the results on a system based on the diazo Meldrum's acid where volatile molecules are produced upon light exposure.

  17. Reliability and life-cycle analysis of deteriorating systems

    CERN Document Server

    Sánchez-Silva, Mauricio

    2016-01-01

    This book compiles and critically discusses modern engineering system degradation models and their impact on engineering decisions. In particular, the authors focus on modeling the uncertain nature of degradation considering both conceptual discussions and formal mathematical formulations. It also describes the basics concepts and the various modeling aspects of life-cycle analysis (LCA).  It highlights the role of degradation in LCA and defines optimum design and operation parameters. Given the relationship between operational decisions and the performance of the system’s condition over time, maintenance models are also discussed. The concepts and models presented have applications in a large variety of engineering fields such as Civil, Environmental, Industrial, Electrical and Mechanical engineering. However, special emphasis is given to problems related to large infrastructure systems. The book is intended to be used both as a reference resource for researchers and practitioners and as an academic text ...

  18. Braking System Modeling and Brake Temperature Response to Repeated Cycle

    Directory of Open Access Journals (Sweden)

    Zaini Dalimus

    2014-12-01

    Full Text Available Braking safety is crucial while driving the passenger or commercial vehicles. Large amount of kinetic energy is absorbed by four brakes fitted in the vehicle. If the braking system fails to work, road accident could happen and may result in death. This research aims to model braking system together with vehicle in Matlab/Simulink software and measure actual brake temperature. First, brake characteristic and vehicle dynamic model were generated to estimate friction force and dissipated heat. Next, Arduino based prototype brake temperature monitoring was developed and tested on the road. From the experiment, it was found that brake temperature tends to increase steadily in long repeated deceleration and acceleration cycle.

  19. Development of System Engineering Technology for Nuclear Fuel Cycle

    International Nuclear Information System (INIS)

    Kim, Ho Dong; Kim, Sung Ki; Song, Kee Chan

    2010-04-01

    This report is aims to establish design requirements for constructing mock-up system of pyroprocess by 2011 to realize long-term goal of nuclear energy promotion comprehensive plan, which is construction of engineering scale pyroprocess integrated process demonstration facility. The development of efficient process for spent fuel and establishment of system engineering technology to demonstrate the process are required to develop nuclear energy continuously. The detailed contents of research for these are as follows; - Design of Mock-up facility for demonstrate pyroprocess, Construction, Approval, Trial run, Performance test - Development of nuclear material accountancy technology for unit processes of pyroprocess and design of safeguards system - Remote operation of demonstrating pyroprocess / Development of maintenance technology and equipment - Establishment of transportation system and evaluation of pre-safety for interim storage system - Deriving and implementation of a method to improve nuclear transparency for commercialization proliferation resistance nuclear fuel cycle Spent fuel which is the most important pending problem of nuclear power development would be reduced and recycled by developing the system engineering technology of pyroprocess facility by 2010. This technology would contribute to obtain JD for the use of spent fuel between the ROK-US and to amend the ROK-US Atomic Energy Agreement scheduled in 2014

  20. The Geometric Phase in Quantum Systems

    International Nuclear Information System (INIS)

    Pascazio, S

    2003-01-01

    The discovery of the geometric phase is one of the most interesting and intriguing findings of the last few decades. It led to a deeper understanding of the concept of phase in quantum mechanics and motivated a surge of interest in fundamental quantum mechanical issues, disclosing unexpected applications in very diverse fields of physics. Although the key ideas underlying the existence of a purely geometrical phase had already been proposed in 1956 by Pancharatnam, it was Michael Berry who revived this issue 30 years later. The clarity of Berry's seminal paper, in 1984, was extraordinary. Research on the topic flourished at such a pace that it became difficult for non-experts to follow the many different theoretical ideas and experimental proposals which ensued. Diverse concepts in independent areas of mathematics, physics and chemistry were being applied, for what was (and can still be considered) a nascent arena for theory, experiments and technology. Although collections of papers by different authors appeared in the literature, sometimes with ample introductions, surprisingly, to the best of my knowledge, no specific and exhaustive book has ever been written on this subject. The Geometric Phase in Quantum Systems is the first thorough book on geometric phases and fills an important gap in the physical literature. Other books on the subject will undoubtedly follow. But it will take a fairly long time before other authors can cover that same variety of concepts in such a comprehensive manner. The book is enjoyable. The choice of topics presented is well balanced and appropriate. The appendices are well written, understandable and exhaustive - three rare qualities. I also find it praiseworthy that the authors decided to explicitly carry out most of the calculations, avoiding, as much as possible, the use of the joke 'after a straightforward calculation, one finds...' This was one of the sentences I used to dislike most during my undergraduate studies. A student is

  1. Nonlinear observer based phase synchronization of chaotic systems

    International Nuclear Information System (INIS)

    Meng Juan; Wang Xingyuan

    2007-01-01

    This Letter analyzes the phase synchronization problem of autonomous chaotic systems. Based on the nonlinear state observer algorithm and the pole placement technique, a phase synchronization scheme is designed. The phase synchronization of a new chaotic system is achieved by using this observer controller. Numerical simulations further demonstrate the effectiveness of the proposed phase synchronization scheme

  2. A vision for an ultra-high resolution integrated water cycle observation and prediction system

    Science.gov (United States)

    Houser, P. R.

    2013-05-01

    Society's welfare, progress, and sustainable economic growth—and life itself—depend on the abundance and vigorous cycling and replenishing of water throughout the global environment. The water cycle operates on a continuum of time and space scales and exchanges large amounts of energy as water undergoes phase changes and is moved from one part of the Earth system to another. We must move toward an integrated observation and prediction paradigm that addresses broad local-to-global science and application issues by realizing synergies associated with multiple, coordinated observations and prediction systems. A central challenge of a future water and energy cycle observation strategy is to progress from single variable water-cycle instruments to multivariable integrated instruments in electromagnetic-band families. The microwave range in the electromagnetic spectrum is ideally suited for sensing the state and abundance of water because of water's dielectric properties. Eventually, a dedicated high-resolution water-cycle microwave-based satellite mission may be possible based on large-aperture antenna technology that can harvest the synergy that would be afforded by simultaneous multichannel active and passive microwave measurements. A partial demonstration of these ideas can even be realized with existing microwave satellite observations to support advanced multivariate retrieval methods that can exploit the totality of the microwave spectral information. The simultaneous multichannel active and passive microwave retrieval would allow improved-accuracy retrievals that are not possible with isolated measurements. Furthermore, the simultaneous monitoring of several of the land, atmospheric, oceanic, and cryospheric states brings synergies that will substantially enhance understanding of the global water and energy cycle as a system. The multichannel approach also affords advantages to some constituent retrievals—for instance, simultaneous retrieval of vegetation

  3. Expression of progesterone receptor membrane component-1 in bovine reproductive system during estrous cycle

    Directory of Open Access Journals (Sweden)

    A.M. Luciano

    2011-09-01

    Full Text Available Several reports suggest the participation of progesterone receptor membrane component 1 (PGRMC1 in progesterone signaling in the reproductive system. This study aimed at investigating the presence and localization of PGRMC1 in bovine ovary, oviduct and uterus, during the follicular and luteal phases of the estrous cycle. In the ovary, PGRMC1 has been detected in surface germinal epithelium, granulosa cells, theca cells and in the germinal vesicle of the oocytesat all stages of folliculogenesis. In the corpus luteum the expression of PGRMC1 was influenced by the stage of the estrous cycle. In the oviducts and in the uterus horns, PGRMC1 was immunolocalized in the luminal epithelium, in the muscle layer cells and in the endothelial cells. In the uterus, PGRMC1 was intensely localized also in the glandular endometrium. However, in the oviducts and in the uterus horns, the localization of PGRMC1 was independent on the stage of the estrous cycle and on whether evaluating the ipsilateral or the contralateral organ. In conclusion, the present immunohistochemical study showed that PGRMC1 is located in various compartments of the bovine female reproductive organs. With the exception of the corpora lutea, PGRMC1 localization showed similar pattern during different stage of the estrous cycle.

  4. Eruption cycles in a basaltic andesite system: insights from numerical modeling

    Science.gov (United States)

    Smekens, J. F.; Clarke, A. B.; De'Michieli Vitturi, M.

    2015-12-01

    Persistently active explosive volcanoes are characterized by short explosive bursts, which often occur at periodic intervals numerous times per day, spanning years to decades. Many of these systems present relatively evolved compositions (andesite to rhyolite), and their cyclic activity has been the subject of extensive work (e.g., Soufriere Hills Volcano, Montserrat). However, the same periodic behavior can also be observed at open systems of more mafic compositions, such as Semeru in Indonesia or Karymsky in Kamchatka for example. In this work, we use DOMEFLOW, a 1D transient numerical model of magma ascent, to identify the conditions that lead to and control periodic eruptions in basaltic andesite systems, where the viscosity of the liquid phase can be drastically lower. Periodic behavior occurs for a very narrow range of conditions, for which the mass balance between magma flux and open-system gas escape repeatedly generates a viscous plug, pressurizes the magma beneath the plug, and then explosively disrupts it. The characteristic timescale and magnitude of the eruptive cycles are controlled by the overall viscosity of the magmatic mixture, with higher viscosities leading to longer cycles and lower flow rates at the top of the conduit. Cyclic eruptions in basaltic andesite systems are observed for higher crystal contents, smaller conduit radii, and over a wider range of chamber pressures than the andesitic system, all of which are the direct consequence of a decrease in viscosity of the melt phase, and in turn in the intensity of the viscous forces generated by the system. Results suggest that periodicity can exist in more mafic systems with relatively lower chamber pressures than andesite and rhyolite systems, and may explain why more mafic magmas sometimes remain active for decades.

  5. The combination of an Environmental Management System and Life Cycle Assessment at the territorial level

    Energy Technology Data Exchange (ETDEWEB)

    Mazzi, Anna; Toniolo, Sara; Catto, Stella; De Lorenzi, Valentina; Scipioni, Antonio, E-mail: scipioni@unipd.it

    2017-03-15

    A framework to include a Life Cycle Assessment in the significance evaluation of the environmental aspects of an Environmental Management System has been studied for some industrial sectors, but there is a literature gap at the territorial level, where the indirect impact assessment is crucial. To overcome this criticality, our research proposes the Life Cycle Assessment as a framework to assess environmental aspects of public administration within an Environmental Management System applied at the territorial level. This research is structured in two parts: the design of a new methodological framework and the pilot application for an Italian municipality. The methodological framework designed supports Initial Environmental Analysis at the territorial level thanks to the results derived from the impact assessment phase. The pilot application in an Italian municipality EMAS registered demonstrates the applicability of the framework and its effectiveness in evaluating the environmental impact assessment for direct and indirect aspects. Through the discussion of the results, we underline the growing knowledge derived by this research in terms of the reproducibility and consistency of the criteria to define the significance of the direct and indirect environmental aspects for a local public administration. - Highlights: • The combination between Environmental Management System and LCA is studied. • A methodological framework is elaborated and tested at the territorial level. • Life Cycle Impact Assessment supports the evaluation of aspects significance. • The framework assures consistency of evaluation criteria on the studied territory.

  6. The combination of an Environmental Management System and Life Cycle Assessment at the territorial level

    International Nuclear Information System (INIS)

    Mazzi, Anna; Toniolo, Sara; Catto, Stella; De Lorenzi, Valentina; Scipioni, Antonio

    2017-01-01

    A framework to include a Life Cycle Assessment in the significance evaluation of the environmental aspects of an Environmental Management System has been studied for some industrial sectors, but there is a literature gap at the territorial level, where the indirect impact assessment is crucial. To overcome this criticality, our research proposes the Life Cycle Assessment as a framework to assess environmental aspects of public administration within an Environmental Management System applied at the territorial level. This research is structured in two parts: the design of a new methodological framework and the pilot application for an Italian municipality. The methodological framework designed supports Initial Environmental Analysis at the territorial level thanks to the results derived from the impact assessment phase. The pilot application in an Italian municipality EMAS registered demonstrates the applicability of the framework and its effectiveness in evaluating the environmental impact assessment for direct and indirect aspects. Through the discussion of the results, we underline the growing knowledge derived by this research in terms of the reproducibility and consistency of the criteria to define the significance of the direct and indirect environmental aspects for a local public administration. - Highlights: • The combination between Environmental Management System and LCA is studied. • A methodological framework is elaborated and tested at the territorial level. • Life Cycle Impact Assessment supports the evaluation of aspects significance. • The framework assures consistency of evaluation criteria on the studied territory.

  7. DNA Damage during G2 Phase Does Not Affect Cell Cycle Progression of the Green Alga Scenedesmus quadricauda

    Science.gov (United States)

    Vítová, Milada; Bišová, Kateřina; Zachleder, Vilém

    2011-01-01

    DNA damage is a threat to genomic integrity in all living organisms. Plants and green algae are particularly susceptible to DNA damage especially that caused by UV light, due to their light dependency for photosynthesis. For survival of a plant, and other eukaryotic cells, it is essential for an organism to continuously check the integrity of its genetic material and, when damaged, to repair it immediately. Cells therefore utilize a DNA damage response pathway that is responsible for sensing, reacting to and repairing damaged DNA. We have studied the effect of 5-fluorodeoxyuridine, zeocin, caffeine and combinations of these on the cell cycle of the green alga Scenedesmus quadricauda. The cells delayed S phase and underwent a permanent G2 phase block if DNA metabolism was affected prior to S phase; the G2 phase block imposed by zeocin was partially abolished by caffeine. No cell cycle block was observed if the treatment with zeocin occurred in G2 phase and the cells divided normally. CDKA and CDKB kinases regulate mitosis in S. quadricauda; their kinase activities were inhibited by Wee1. CDKA, CDKB protein levels were stabilized in the presence of zeocin. In contrast, the protein level of Wee1 was unaffected by DNA perturbing treatments. Wee1 therefore does not appear to be involved in the DNA damage response in S. quadricauda. Our results imply a specific reaction to DNA damage in S. quadricauda, with no cell cycle arrest, after experiencing DNA damage during G2 phase. PMID:21603605

  8. DNA damage during G2 phase does not affect cell cycle progression of the green alga Scenedesmus quadricauda.

    Directory of Open Access Journals (Sweden)

    Monika Hlavová

    Full Text Available DNA damage is a threat to genomic integrity in all living organisms. Plants and green algae are particularly susceptible to DNA damage especially that caused by UV light, due to their light dependency for photosynthesis. For survival of a plant, and other eukaryotic cells, it is essential for an organism to continuously check the integrity of its genetic material and, when damaged, to repair it immediately. Cells therefore utilize a DNA damage response pathway that is responsible for sensing, reacting to and repairing damaged DNA. We have studied the effect of 5-fluorodeoxyuridine, zeocin, caffeine and combinations of these on the cell cycle of the green alga Scenedesmus quadricauda. The cells delayed S phase and underwent a permanent G2 phase block if DNA metabolism was affected prior to S phase; the G2 phase block imposed by zeocin was partially abolished by caffeine. No cell cycle block was observed if the treatment with zeocin occurred in G2 phase and the cells divided normally. CDKA and CDKB kinases regulate mitosis in S. quadricauda; their kinase activities were inhibited by Wee1. CDKA, CDKB protein levels were stabilized in the presence of zeocin. In contrast, the protein level of Wee1 was unaffected by DNA perturbing treatments. Wee1 therefore does not appear to be involved in the DNA damage response in S. quadricauda. Our results imply a specific reaction to DNA damage in S. quadricauda, with no cell cycle arrest, after experiencing DNA damage during G2 phase.

  9. Influence of bodybuilding classes on physical qualities of the qualified sportswomen in different phases of the specific biological cycle

    Directory of Open Access Journals (Sweden)

    Vyacheslav Mulik

    2017-02-01

    Full Text Available Purpose: to conduct researches of influence of classes of the sportswomen who are going in for bodybuilding and fitness-bikini on manifestation of physical qualities in different phases of the ovarian-menstrual cycle. Material & Methods: researches were conducted in sports fitness-clubs of Kharkov "Feromon", "Gorod", “King” with the qualified sportswomen who are going in for bodybuilding and fitness-bikini within 3 months of the preparatory period in number of 14 people. We used as methods of the research: the analysis of references and testing of level of motive qualities in separate phases of OMC. Results: the theoretical analysis of features of the accounting of phases of OMC at sportswomen is submitted and the testing of the level of development of physical qualities in different phases of the specific biological cycle at the qualified sportswomen, who are going in for bodybuilding, is held. Conclusions: the received results demonstrate that physical efficiency of the qualified sportswomen, who are going in for bodybuilding, is not identical in phases of the ovarian-menstrual cycle. It is revealed that the best conditions for performance of considerable exercise stresses in post-ovulatory and post-menstrual phases of OMC, therefore it is expedient to plan them in the preparatory periods of the qualified sportswomen, who are going in for bodybuilding.

  10. EFFECT OF THE ROTOR CRANK SYSTEM ON CYCLING PERFORMANCE

    Directory of Open Access Journals (Sweden)

    Simon A. Jobson

    2009-09-01

    Full Text Available The aim of this study was to evaluate the impact of a novel crank system on laboratory time-trial cycling performance. The Rotor system makes each pedal independent from the other so that the cranks are no longer fixed at 180°. Twelve male competitive but non-elite cyclists (mean ± s: 35 ± 7 yr, Wmax = 363 ± 38 W, VO2peak = 4.5 ± 0.3 L·min-1 completed 6-weeks of their normal training using either a conventional (CON or the novel Rotor (ROT pedal system. All participants then completed two 40.23-km time-trials on an air-braked ergometer, one using CON and one using ROT. Mean performance speeds were not different between trials (CON = 41.7 km·h-1 vs. ROT = 41.6 km·h-1, P > 0.05. Indeed, the pedal system used during the time-trials had no impact on any of the measured variables (power output, cadence, heart rate, VO2, RER, gross efficiency. Furthermore, the ANOVA identified no significant interaction effect between main effects (Time-trial crank system*Training crank system, P > 0.05. To the authors' knowledge, this is the first study to examine the effects of the Rotor system on endurance performance rather than endurance capacity. These results suggest that the Rotor system has no measurable impact on time-trial performance. However, further studies should examine the importance of the Rotor 'regulation point' and the suggestion that the Rotor system has acute ergogenic effects if used infrequently

  11. Phase and amplitude detection system for the Stanford Linear Accelerator

    International Nuclear Information System (INIS)

    Fox, J.D.; Schwarz, H.D.

    1983-01-01

    A computer controlled phase and amplitude detection system to measure and stabilize the rf power sources in the Stanford Linear Accelerator is described. This system measures the instantaneous phase and amplitude of a 1 microsecond 2856 MHz rf pulse and will be used for phase feedback control and for amplitude and phase jitter detection. This paper discusses the measurement system performance requirements for the operation of the Stanford Linear Collider, and the design and implementation of the phase and amplitude detection system. The fundamental software algorithms used in the measurement are described, as is the performance of the prototype phase and amplitude detector system

  12. Thermo- economical consideration of Regenerative organic Rankine cycle coupling with the absorption chiller systems incorporated in the trigeneration system

    International Nuclear Information System (INIS)

    Anvari, Simin; Taghavifar, Hadi; Parvishi, Alireza

    2017-01-01

    Highlights: • A new trigeneration cycle was studied from a new viewpoint of exergoeconomic and thermodynamic. • Organic Rankine and refrigeration cycles are used for recovery waste heat of cogeneration system. • Application of trigeneration cycles is advantageous in economical and thermodynamic aspects. - Abstract: In this paper, a combined cooling, heating and power cycle is proposed consisting of three sections of gas turbine and heat recovery steam generator cycle, Regenerative organic Rankine cycle, and absorption refrigeration cycle. This trigeneration cycle is subjected to a thorough thermodynamic and exergoeconomic analysis. The principal goal followed in the investigation is to address the thermodynamic and exergoeconomic of a trigeneration cycle from a new prospective such that the economic and thermodynamic viability of incorporating Regenerative organic Rankine cycle, and absorption refrigeration cycle to the gas turbine and heat recovery steam generator cycle is being investigated. Thus, the cost-effectiveness of the introduced method can be studied and further examined. The results indicate that adding Regenerative organic Rankine cycle to gas turbine and heat recovery steam generator cycle leads to 2.5% increase and the addition of absorption refrigeration cycle to the gas turbine and heat recovery steam generator/ Regenerative Organic Rankine cycle would cause 0.75% increase in the exergetic efficiency of the entire cycle. Furthermore, from total investment cost of the trigeneration cycle, only 5.5% and 0.45% results from Regenerative organic Rankine cycle and absorption refrigeration cycles, respectively.

  13. Phase diagrams of Pr-C system

    International Nuclear Information System (INIS)

    Eremenko, V.N.; Velikanova, T.Ya.; Gordijchuk, O.V.

    1988-01-01

    Results of the X-ray phase, metallographic and high-temperature differential thermal analysis are used for the first time to plot a diagram of the Pr-C system state. Carbides are formed in the system: Pr 2 C 3 with the bcc-structure of the Pu 2 C 3 type and with the period a 0 = 0.85722+-0.00026 within the phase region + 2 C 3 >, a 0 0.86078+-0.00016 nm - within the region 2 C 3 >+α-PrC 2 ; dimorphous PrC 2 : α-PrC 2 with the bct-structure of the CaC 2 type and periods a 0.38517+-0.00011, c 0 = 0.64337+-0.00019 nm; β-PrC 2 with the fcc-structure, probably, of KCN type. Dicarbide melts congruently at 2320 grad. C, forming eutectics with graphite at 2254+-6 grad. C and composition of 71.5% (at.)C. It is polymorphously transformed in the phase region 2 C 3 > + 2 > at 1145+-4 grad. C, and in the region 2 >+C at 1134+-4 grad. C. Sesquicarbide melts incongruently at 1545+-4 grad. C. The eutectic reaction L ↔ + 2 C 3 > occurs at 800+-4 grad. C, the eutectic composition ∼ 15% (at.)C. The temperature of the eutectoid reaction ↔ + 2 C 3 > is 675+-6 grad C. The limiting carbon solubility in β-Pr is about 8 and in α-Pr it is about 5% (at.)

  14. Topological Classification of Limit Cycles of Piecewise Smooth Dynamical Systems and Its Associated Non-Standard Bifurcations

    Directory of Open Access Journals (Sweden)

    John Alexander Taborda

    2014-04-01

    Full Text Available In this paper, we propose a novel strategy for the synthesis and the classification of nonsmooth limit cycles and its bifurcations (named Non-Standard Bifurcations or Discontinuity Induced Bifurcations or DIBs in n-dimensional piecewise-smooth dynamical systems, particularly Continuous PWS and Discontinuous PWS (or Filippov-type PWS systems. The proposed qualitative approach explicitly includes two main aspects: multiple discontinuity boundaries (DBs in the phase space and multiple intersections between DBs (or corner manifolds—CMs. Previous classifications of DIBs of limit cycles have been restricted to generic cases with a single DB or a single CM. We use the definition of piecewise topological equivalence in order to synthesize all possibilities of nonsmooth limit cycles. Families, groups and subgroups of cycles are defined depending on smoothness zones and discontinuity boundaries (DB involved. The synthesized cycles are used to define bifurcation patterns when the system is perturbed with parametric changes. Four families of DIBs of limit cycles are defined depending on the properties of the cycles involved. Well-known and novel bifurcations can be classified using this approach.

  15. The Next World War: World-System Cycles and Trends

    Directory of Open Access Journals (Sweden)

    Christopher Chase-Dunn

    1995-08-01

    Full Text Available This essay places the contemporary period of global development in long-run historical perspective, elaborates a model of world-system cycles and trends, and discusses the main structural forces influencing the probability of future war among core powers. The possible continuation of the cycle of hegemonic rivalry is discussed in terms of the similarities and differences between the coming three decades and earlier periods in which a declining hegemon was challenged by upwardly mobile states. Possible bids for economic and political hegemony by Japan, Germany, China and the United States are discussed, as are the possibilities for different coalitions in East Asia and Europe. The phenomenon of bloc formation is discussed in a long-term perspective that includes earlier periods of colonial empire and "commonwealth." We conclude that there is a significantly high probability that warfare among core states could occur in the 2020s. The prospects for global state formation within the next three decades are considered. We recommend a combination of the build-up of U.N. peace-keeping forces and the continuation of U.S. military strength as the least worst and most feasible solution to the problem of avoiding nuclear holocaust in the 2020s.

  16. A Survey of Phase Change Memory Systems

    Institute of Scientific and Technical Information of China (English)

    夏飞; 蒋德钧; 熊劲; 孙凝晖

    2015-01-01

    As the scaling of applications increases, the demand of main memory capacity increases in order to serve large working set. It is difficult for DRAM (dynamic random access memory) based memory system to satisfy the memory capacity requirement due to its limited scalability and high energy consumption. Compared to DRAM, PCM (phase change memory) has better scalability, lower energy leakage, and non-volatility. PCM memory systems have become a hot topic of academic and industrial research. However, PCM technology has the following three drawbacks: long write latency, limited write endurance, and high write energy, which raises challenges to its adoption in practice. This paper surveys architectural research work to optimize PCM memory systems. First, this paper introduces the background of PCM. Then, it surveys research efforts on PCM memory systems in performance optimization, lifetime improving, and energy saving in detail, respectively. This paper also compares and summarizes these techniques from multiple dimensions. Finally, it concludes these optimization techniques and discusses possible research directions of PCM memory systems in future.

  17. Environmental and resources geochemistry of earth system mass transfer mechanism, geochemical cycle and the influence of human activity

    CERN Document Server

    Shikazono, Naotatsu

    2015-01-01

    The Earth system consists of subsystems that include the atmosphere, hydrosphere (water), geosphere (rocks, minerals), biosphere, and humans. In order to understand these subsystems and their interactions, it is essential to clarify the mass transfer mechanism, geochemical cycle, and influence of human activity on the natural environment. This book presents fundamental theories (thermodynamics, kinetics, mass balance model, coupling models such as the kinetics-fluid flow model, the box model, and others) concerning mechanisms in weathering, formation of hydrothermal ore deposits, hydrothermal alteration, formation of groundwater quality, and the seawater system. The interaction between fluids (atmosphere, water) and solid phases (rocks, minerals) occurs both in low-temperature and also in high-temperature systems. This book considers the complex low-temperature cycle with the high-temperature cycle, a combination that has not been dealt with in previous books concerning Earth systems. Humanity is a small part...

  18. A new Gsdma3 mutation affecting anagen phase of first hair cycle

    International Nuclear Information System (INIS)

    Tanaka, Shigekazu; Tamura, Masaru; Aoki, Aya; Fujii, Tomoaki; Komiyama, Hiromitsu; Sagai, Tomoko; Shiroishi, Toshihiko

    2007-01-01

    Recombination-induced mutation 3 (Rim3) is a spontaneous mouse mutation that exhibits dominant phenotype of hyperkeratosis and hair loss. Fine linkage analysis of Rim3 and sequencing revealed a novel single point mutation, G1124A leading to Ala348Thr, in Gsdma3 in chromosome 11. Transgenesis with BAC DNA harboring the Rim3-type Gsdma3 recaptured the Rim3 phenotype, providing direct evidence that Gsdma3 is the causative gene of Rim3. We examined the spatial expression of Gsdma3 and characterized the Rim3 phenotype in detail. Gsdma3 is expressed in differentiated epidermal cells in the skin, but not in the proliferating epidermal cells. Histological analysis of Rim3 mutant showed hyperplasia of the epidermal cells in the upper hair follicles and abnormal anagen phase at the first hair cycle. Furthermore, immunohistochemical analysis revealed hyperproliferation and misdifferentiation of the upper follicular epidermis in Rim3 mutant. These results suggest that Gsdma3 is involved in the proliferation and differentiation of epidermal stem cells

  19. Effect of menstrual cycle phase and hormonal treatments on evaluation of tubal patency in baboons.

    Science.gov (United States)

    Jensen, Jeffrey T; Hanna, Carol; Mishler, Emily; Lim, Jeong Y; Slayden, Ov D

    2018-02-01

    We evaluated whether menstrual cycle phase influences the assessment of tubal patency by hysterosalpingography (HSG) in baboons. Retrospective analysis of baseline tubal patency studies and serum estradiol (E 2 ) and progesterone (P4) values obtained from female baboons used as models for development of non-surgical permanent contraception in women. The main outcome measure was bilateral tubal patency (BTP) in relationship with estradiol level. Female baboons (n = 110) underwent a single (n = 81), two (n = 26), or three (n = 3) HSG examinations. In 33/142 (23%) HSG examinations, one or both tubes showed functional occlusion (FO). The median E 2 in studies with BTP (49 pg/mL) was significantly higher than in those studies with FO (32 pg/mL, P = .005). Among 18 animals with repeat examinations where serum E 2 changed from <60 to ≥ 60 pg/mL, 13 results changed from FO to BTP (P = .0001). No sets showed a change from BTP to FO with an increase in estradiol. In baboons, functional occlusion of the fallopian tube is associated with low estradiol levels, supporting a role for estrogen-mediated relaxation of the utero-tubal junction. © 2017 The Authors. Journal of Medical Primatology Published by John Wiley & Sons Ltd.

  20. Executive Summary of Ares V: Lunar Capabilities Concept Review Through Phase A-Cycle 3

    Science.gov (United States)

    Holladay, J. B.; Baggett, K. E.; Feldman, S. M.

    2011-01-01

    This Technical Memorandum (TM) was generated as an overall Ares V summary from the Lunar Capabilities Concept Review (LCCR) through Phase A-Cycle 3 (PA-C3) with the intent that it may be coupled with separately published appendices for a more detailed, integrated narrative. The Ares V has evolved from the initial point of departure (POD) 51.00.48 LCCR configuration to the current candidate POD, PA-C3D, and the family of vehicles concept that contains vehicles PA-C3A through H. The logical progression from concept to POD vehicles is summarized in this TM and captures the trade space and performance of each. The family-of-vehicles concept was assessed during PA-C3 and offered flexibility in the path forward with the ability to add options deemed appropriate. A description of each trade space is given in addition to a summary of each Ares V element. The Ares V contributions to a Mars campaign are also highlighted with the goal of introducing Ares V capabilities within the trade space. The assessment of the Ares V vehicle as it pertains to Mars missions remained locked to the architecture presented in Mars Design Reference Authorization 5.0 using the PA-C3D vehicle configuration to assess Mars transfer vehicle options, in-space EDS capabilities, docking adaptor and propellant transfer assessments, and lunar and Mars synergistic potential.

  1. Cell cycle phase of nondividing cells in aging human cell cultures determined by DNA content and chromosomal constitution

    International Nuclear Information System (INIS)

    Yanishevsky, R.M.

    1975-01-01

    Human diploid cell cultures, strain WI-38, have a finite proliferative capacity and have been proposed as a model of biological aging. To identify the cell cycle phase of the nondividing cells, cultures of various ages were exposed to 3 Hdt for 48 hours to label dividing cells, then the cycle phase was identified for individual cells by one of two methods, and finally, the proliferative status of the same cells was scored by autoradiographic evidence of 3 HdT uptake. The methods to identify the cycle phase were: determination of DNA strain content by Feulgen scanning cytophotometry, and determination of chromosome constitution by the technique of premature chromosome condensation (PCC). Preliminary experiments showed the effect of continuous exposure to various levels of 3 HdT on cell growth. High levels of 3 HdT inhibited cell cycle traverse: the cell number and labeling index curves reached a plateau; the cell volume increased; the cells accumulated with 4C DNA contents and it appeared that they blocked in G 2 phase. This pattern is consistent with a radiation effect. (U.S.)

  2. Cell cycle phase dependent role of DNA polymerase beta in DNA repair and survival after ionizing radiation.

    NARCIS (Netherlands)

    Vermeulen, C.; Verwijs-Janssen, M.; Begg, A.C.; Vens, C.

    2008-01-01

    PURPOSE: The purpose of the present study was to determine the role of DNA polymerase beta in repair and response after ionizing radiation in different phases of the cell cycle. METHODS AND MATERIALS: Synchronized cells deficient and proficient in DNA polymerase beta were irradiated in different

  3. Guidance for the evaluation of innovative nuclear reactors and fuel cycles. Report of Phase 1A of the International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO)

    International Nuclear Information System (INIS)

    2003-06-01

    technicians of the calibre and size needed to support a truly substantial nuclear contribution to global energy supplies. To set out the boundary conditions for the desired innovations of nuclear energy systems, INPRO established several task groups to define: Prospects and Potentials of nuclear power within the next 50 years; User Requirements for innovative nuclear energy systems (INS) in the area of Economics, Sustainability and Environment, Safety, Waste Management, Proliferation Resistance, and Cross Cutting Issues; and Methodology for Assessment of INS. Having completed these tasks, it is planned that several Member States will apply the INPRO methodology to make a judgement on the potential of INS under consideration for development, to specify corresponding research, development and demonstration (RD and D) needs for their development, and to identify improvements in the methodology. The results achieved as of the end of April 2003 (Phase 1A) are presented in this report. It is intended to issue separately the working material on which this report is based and which was produced at a number of consultancy meetings held during the course of the Project

  4. Energy systems. Tome 3: advanced cycles, low environmental impact innovative systems

    International Nuclear Information System (INIS)

    Gicquel, R.

    2009-01-01

    This third tome about energy systems completes the two previous ones by showing up advanced thermodynamical cycles, in particular having a low environmental impact, and by dealing with two other questions linked with the study of systems with a changing regime operation: - the time management of energy, with the use of thermal and pneumatic storage systems and time simulation (schedule for instance) of systems (solar energy type in particular); - the technological dimensioning and non-nominal regime operation studies. Because this last topic is particularly complex, new functionalities have been implemented mainly by using the external classes mechanism, which allows the user to freely personalize his models. This tome is illustrated with about 50 examples of cycles modelled with Thermoptim software. Content: foreword; 1 - generic external classes; 2 - advanced gas turbine cycles; 3 - evaporation-concentration, mechanical steam compression, desalination, hot gas drying; 4 - cryogenic cycles; 5 - electrochemical converters; 6 - global warming, CO 2 capture and sequestration; 7 - future nuclear reactors (coupled to Hirn and Brayton cycles); 8 - thermodynamic solar cycles; 10 - pneumatic and thermal storage; 11 - calculation of thermodynamic solar facilities; 12 - problem of technological dimensioning and non-nominal regime; 13 - exchangers modeling and parameterizing for the dimensioning and the non-nominal regime; 14 - modeling and parameterizing of volumetric compressors; 15 - modeling and parameterizing of turbo-compressors and turbines; 16 - identification methodology of component parameters; 17 - case studies. (J.S.)

  5. Graphical and statistical techniques for cardiac cycle time (phase) dependent changes in interbeat interval.

    NARCIS (Netherlands)

    Jennings, J.R.; van der Molen, M.W.; Somsen, R.J.M.; Ridderinkhof, K.R.

    1991-01-01

    Cardiac cycle time effects refer to the relative lengthening or shortening of a single cardiac cycle as a function of when in the cycle brief sensorimotor events occur. These effects may provide short-latency measures of cardiac sensitivity to Psychological events. Conventional representations have,

  6. Advancing Integrated Systems Modelling Framework for Life Cycle Sustainability Assessment

    Directory of Open Access Journals (Sweden)

    Anthony Halog

    2011-02-01

    Full Text Available The need for integrated methodological framework for sustainability assessment has been widely discussed and is urgent due to increasingly complex environmental system problems. These problems have impacts on ecosystems and human well-being which represent a threat to economic performance of countries and corporations. Integrated assessment crosses issues; spans spatial and temporal scales; looks forward and backward; and incorporates multi-stakeholder inputs. This study aims to develop an integrated methodology by capitalizing the complementary strengths of different methods used by industrial ecologists and biophysical economists. The computational methodology proposed here is systems perspective, integrative, and holistic approach for sustainability assessment which attempts to link basic science and technology to policy formulation. The framework adopts life cycle thinking methods—LCA, LCC, and SLCA; stakeholders analysis supported by multi-criteria decision analysis (MCDA; and dynamic system modelling. Following Pareto principle, the critical sustainability criteria, indicators and metrics (i.e., hotspots can be identified and further modelled using system dynamics or agent based modelling and improved by data envelopment analysis (DEA and sustainability network theory (SNT. The framework is being applied to development of biofuel supply chain networks. The framework can provide new ways of integrating knowledge across the divides between social and natural sciences as well as between critical and problem-solving research.

  7. ALKASYS, Rankine-Cycle Space Nuclear Power System

    International Nuclear Information System (INIS)

    2001-01-01

    1 - Description of program or function: The program ALKASYS is used for the creation of design concepts of multimegawatt space power systems that employ potassium Rankine power conversion cycles. 2 - Method of solution: ALKASYS calculates performance and design characteristics and mass estimates for the major subsystems composing the total power system. Design and engineering performance characteristics are determined by detailed engineering procedures rather than by empirical algorithms. Mass estimates are developed using basic design principles augmented in some cases by empirical coefficients determined from the literature. The reactor design is based on a fast spectrum, metallic-clad rod fuel element containing UN pellets. 3 - Restrictions on the complexity of the problem: ALKASYS was developed primarily for the analysis of systems with electric power in the range from 1,000 to 25,000 kW(e) and full-power life from 1 to 10 years. The program should be used with caution in systems that are limited by heat flux (which might indicate need for extended surfaces on fuel elements) or criticality (which might indicate the need for other geometries or moderators)

  8. Remote maintenance system technology development for nuclear fuel cycle plants

    International Nuclear Information System (INIS)

    Kashihara, Hidechiyo

    1984-01-01

    The necessity of establishing the technology of remote maintenance, the kinds of maintenance techniques and the change, the image of a facility adopting remote maintenance canyon process, and the outline of the R and D plan to put remote maintenance canyon process in practical use are described. As the objects of development, there are twin arm type servo manipulator system, rack system, remote tube connectors, solution sampling system, inspection system for in-cell equipment, and large plugs for wall penetration. The outline of those are also reported. The development of new remote maintenance technology has been forwarded in the Tokai Works aiming at the application to a glass solidification pilot plant and a FBR fuel recycling test facility. The lowering of the rate of utilization of cells due to poor accessibility and the increase of radiation exposure of workers must be overcome to realize nuclear fuel cycle technology. The maintenance technology is classified into crane canyon method, direct maintenance cell method, remote maintenance cell method and remote maintenance canyon method, and those are described briefly. The development plan of remote maintenance technology is outlined. (Kako, I.)

  9. Argonne Fuel Cycle Facility ventilation system -- modeling and results

    International Nuclear Information System (INIS)

    Mohr, D.; Feldman, E.E.; Danielson, W.F.

    1995-01-01

    This paper describes an integrated study of the Argonne-West Fuel Cycle Facility (FCF) interconnected ventilation systems during various operations. Analyses and test results include first a nominal condition reflecting balanced pressures and flows followed by several infrequent and off-normal scenarios. This effort is the first study of the FCF ventilation systems as an integrated network wherein the hydraulic effects of all major air systems have been analyzed and tested. The FCF building consists of many interconnected regions in which nuclear fuel is handled, transported and reprocessed. The ventilation systems comprise a large number of ducts, fans, dampers, and filters which together must provide clean, properly conditioned air to the worker occupied spaces of the facility while preventing the spread of airborne radioactive materials to clean am-as or the atmosphere. This objective is achieved by keeping the FCF building at a partial vacuum in which the contaminated areas are kept at lower pressures than the other worker occupied spaces. The ventilation systems of FCF and the EBR-II reactor are analyzed as an integrated totality, as demonstrated. We then developed the network model shown in Fig. 2 for the TORAC code. The scope of this study was to assess the measured results from the acceptance/flow balancing testing and to predict the effects of power failures, hatch and door openings, single-failure faulted conditions, EBR-II isolation, and other infrequent operations. The studies show that the FCF ventilation systems am very controllable and remain stable following off-normal events. In addition, the FCF ventilation system complex is essentially immune to reverse flows and spread of contamination to clean areas during normal and off-normal operation

  10. A Systematic Modelling Framework for Phase Transfer Catalyst Systems

    DEFF Research Database (Denmark)

    Anantpinijwatna, Amata; Sales-Cruz, Mauricio; Hyung Kim, Sun

    2016-01-01

    Phase-transfer catalyst systems contain two liquid phases, with a catalyst (PTC) that transfers between the phases, driving product formation in one phase and being regenerated in the other phase. Typically the reaction involves neutral species in an organic phase and regeneration involves ions i....... The application of the framework is made to two cases in order to highlight the performance and issues of activity coefficient models for predicting design and operation and the effects when different organic solvents are employed....

  11. Uncertainties in life cycle assessment of waste management systems

    DEFF Research Database (Denmark)

    Clavreul, Julie; Christensen, Thomas Højlund

    2011-01-01

    Life cycle assessment has been used to assess environmental performances of waste management systems in many studies. The uncertainties inherent to its results are often pointed out but not always quantified, which should be the case to ensure a good decisionmaking process. This paper proposes...... a method to assess all parameter uncertainties and quantify the overall uncertainty of the assessment. The method is exemplified in a case study, where the goal is to determine if anaerobic digestion of organic waste is more beneficial than incineration in Denmark, considering only the impact on global...... warming. The sensitivity analysis pointed out ten parameters particularly highly influencing the result of the study. In the uncertainty analysis, the distributions of these ten parameters were used in a Monte Carlo analysis, which concluded that incineration appeared more favourable than anaerobic...

  12. Tests of prototype salt stripper system for IFR fuel cycle

    International Nuclear Information System (INIS)

    Carls, E.L.; Blaskovitz, R.J.; Johnson, T.R.; Ogata, T.

    1993-01-01

    One of the waste treatment steps for the on-site reprocessing of spent fuel from the Integral Fast Reactor fuel cycles is stripping of the electrolyte salt used in the electrorefining process. This involves the chemical reduction of the actinides and rare earth chlorides forming metals which then dissolve in a cadmium pool. To develop the equipment for this step, a prototype salt stripper system has been installed in an engineering scale argon-filled glovebox. Pumping trails were successful in transferring 90 kg of LiCl-KCl salt containing uranium and rare earth metal chlorides at 500 degree C from an electrorefiner to the stripper vessel at a pumping rate of about 5 L/min. The freeze seal solder connectors which were used to join sections of the pump and transfer line performed well. Stripping tests have commenced employing an inverted cup charging device to introduce a Cd-15 wt % Li alloy reductant to the stripper vessel

  13. Evaluation of life cycle inventory data for recycling systems

    DEFF Research Database (Denmark)

    Brogaard, Line Kai-Sørensen; Damgaard, Anders; Jensen, Morten Bang

    2014-01-01

    This paper reviews databases on material recycling (primary as well as secondary production) used in life cycle assessments (LCA) of waste management systems. A total of 366 datasets, from 1980 to 2010 and covering 14 materials, were collected from databases and reports. Totals for CO2-equivalent...... the primary production of newsprint, HDPE and glass were 238%, 443% and 452%, respectively. For steel and aluminium the differences were 1761% and 235%, respectively. There is a severe lack of data for some recycled materials; for example, only one dataset existed for secondary cardboard. The study shows...... datasets to use could not be determined from the study. However, from the gathered data, recycling in general showed lower emission of CO2 per kg material than primary production, so the recycling of materials (considered in this study) is thus beneficial in most cases....

  14. The electronuclear cycle: from fission to new reactor systems

    International Nuclear Information System (INIS)

    Belier, G.; Cugnon, J.; Lapoux, V.; Liatard, E.; Porquet, Marie-Genevieve; Rudolf, G.

    2006-09-01

    The Joliot Curie School trains each year, and since 1981, PhD students, post-Doctorates and researchers on scientific breakthroughs performed in a topic related to nuclear physics, in a broad range. These proceedings brings together the 11 lectures given at the 2006 session of Joliot Curie School on the topic of the electronuclear cycle: - Fission: from phenomenology to theory (Berger, J.F.); - Physics of nuclear reactors (Baeten, P.); - Data modeling and evaluation (Bauge, E.; Hilaire, S.); - Measurement of cross sections of interest for minor actinides incineration (Jurado, B.); - Spallation data and modelling for hybrid reactors (Boudard, A.); - Nuclear wastes: overview (Billard, I.); - Long living nuclear wastes transmutation processes and feasibility (Varaine, F.); - Hybrid reactors: recent advances for a demonstrator (Billebaud, A.); - Systems of the future and strategy (David, S.); - Non-nuclear energies (Nifenecker, H.); - Fundamental physics with ultracold neutrons (Protasov, K). The last section is a compilation of abstracts of presentations given by Young searchers' (Young searchers' seminars)

  15. Phase tracking system for ultra narrow bandwidth applications

    NARCIS (Netherlands)

    Hill, M.T.; Cantoni, A.

    2002-01-01

    Recent advances make it possible to mitigate a number of drawbacks of conventional phase locked loops. These advances permit the design of phase tracking systems with much improved characteristics that are sought after in modern communication system applications. A new phase tracking system is

  16. Development of alternate extractant systems for fast reactor fuel cycle

    International Nuclear Information System (INIS)

    Vasudeva Rao, P.R.; Suresh, A.; Venkatesan, K.A.; Srinivasan, T.G.; Raj, Baldev

    2007-01-01

    Due to the limitations of TBP in processing of high burn-up, Pu-rich fast reactor fuels, there is a need to develop alternate extractants for fast reactor fuel processing. In this context, our Centre has been examining the suitability of alternate tri-alkyl phosphates. Third phase formation in the extraction of Th(IV) by TBP, tri-n-amyl phosphate (TAP) and tri-2-methyl-butyl phosphate (T2MBP) from nitric acid media has been investigated under various conditions to derive conclusions on their application for extraction of Pu at macro levels. The chemical and radiolytic degradation of tri-n-amyl-phosphate (TAP) diluted in normal paraffin hydrocarbon (NPH) in the presence of nitric acid has been investigated by the measurement of plutonium retention in organic phase. The potential application of room temperature ionic liquids (RTILs) for reprocessing of spent nuclear fuel has been explored. Extraction of uranium (VI) and palladium (II) from nitric acid medium by commercially available RTIL and tri-n-butyl phosphate solution in RTIL have been studied and the feasibility of electrodeposition of uranium as uranium oxide (UO 2 ) and palladium (II) as metallic palladium from the loaded organic phase have been demonstrated. This paper describes results of the above studies and discusses the suitability of the systems for fast reactor fuel reprocessing. (authors)

  17. Design of a power conversion system for an indirect cycle, helium cooled pebble bed reactor system

    International Nuclear Information System (INIS)

    Wang, C.; Ballinger, R.G.; Stahle, P.W.; Demetri, E.; Koronowski, M.

    2002-01-01

    A design is presented for the turbomachinery for an indirect cycle, closed, helium cooled modular pebble bed reactor system. The design makes use of current technology and will operate with an overall efficiency of 45%. The design uses an intermediate heat exchanger which isolated the reactor cycle from the turbomachinery. This design excludes radioactive fission products from the turbomachinery. This minimizes the probability of an air ingress accident and greatly simplifies maintenance. (author)

  18. Martensitic transformation, fcc and hcp relative phase stability, and thermal cycling effects in Fe-Mn and Fe-Mn-X Alloys (X = Si, Co)

    International Nuclear Information System (INIS)

    Baruj, Alberto

    1999-01-01

    In this Thesis we present a study of the fcc and hcp relative phase stability in the Fe-Mn and Fe-Mn-Co systems. In particular, we have investigated the effect of two main factors affecting the relative phase stability: changes in the chemical composition of the alloys and changes in the density of crystalline defects in the microstructure.In order to analyse the effect of chemical composition, we have performed an experimental study of the fcc/hcp martensitic transformation temperatures in Fe-Mn-Co alloys in the composition range lying between 15% and 34% Mn, and between 1% and 16% Co.We have measured the martensitic transformation temperatures by means of dilatometry and electrical resistivity.We have combined this information with measurements of the fcc/hcp martensitic transformation temperatures in Co-rich alloys to perform a modelling of the Gibbs energy function for the hcp phase in the Fe-Mn-Co and Fe-Co systems.We found that, for alloys in the Mn range between 17% and 25%, Co additions tend to stabilise slightly the fcc phase.In the alloys with Mn contents below that range, increasing the amount of Co stabilise the bcc phase. In alloys with Mn contents above 25% the Neel temperature is depressed by the addition of Co, which stabilise the hcp phase.In order to investigate the effect of changes in the density of crystalline defects, we have performed thermal cycling experiments through the fcc/hcp martensitic transformation in Fe-Mn, Fe-Mn-Co and Fe-Mn-Si alloys.We have applied the thermodynamic description obtained before in order to analyse these experiments.We found in the thermal cycling experiments a first stage where the martensitic transformation is promoted.This stage occurs in all the studied alloys during the first cycle or the two first cycles.Increasing the number of thermal cycles, the promotion stage is replaced by an inhibition of the transformation stage.We propose a possible microstructural interpretation of these phenomena where the plastic

  19. Power conversion systems based on Brayton cycles for fusion reactors

    International Nuclear Information System (INIS)

    Linares, J.I.; Herranz, L.E.; Moratilla, B.Y.; Serrano, I.P.

    2011-01-01

    This paper investigates Brayton power cycles for fusion reactors. Two working fluids have been explored: helium in classical configurations and CO 2 in recompression layouts (Feher cycle). Typical recuperator arrangements in both cycles have been strongly constrained by low temperature of some of the energy thermal sources from the reactor. This limitation has been overcome in two ways: with a combined architecture and with dual cycles. Combined architecture couples the Brayton cycle with a Rankine one capable of taking advantage of the thermal energy content of the working fluid after exiting the turbine stage (iso-butane and steam fitted best the conditions of the He and CO 2 cycles, respectively). Dual cycles set a specific Rankine cycle to exploit the lowest quality thermal energy source, allowing usual recuperator arrangements in the Brayton cycle. The results of the analyses indicate that dual cycles could reach thermal efficiencies around 42.8% when using helium, whereas thermal performance might be even better (46.7%), if a combined CO 2 -H 2 O cycle was set.

  20. Survey on the life cycle system of a product with shared information; Joho kyoyugata product life cycle system ni kansuru chosa hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    This report provides and proposes new concept and optimization technology on the life cycle system of product for emission minimum. For the proposed life cycle system of product with shared information, the global emission minimum is realized by considering the final emission, the information is given to the product and shared in all the life cycle system, the information sending function is considered from the product, and the information necessary for material processing are actively used. For this life cycle system of product, development of the information model for the system, development of the technology of data saving, renewing, searching and sending, development of sensing and re-using technologies of the product for life cycle, development of the technology attaching information in the product for emission minimum, design of the guidelines of material composition, and research and development of materials for emission minimum are extracted and provided as tasks. 26 refs., 69 figs., 8 tabs.

  1. Assessing an Adaptive Cycle in a Social System under External Pressure to Change: the Importance of Intergroup Relations in Recreational Fisheries Governance

    Directory of Open Access Journals (Sweden)

    Katrin Daedlow

    2011-06-01

    Full Text Available The adaptive cycle constitutes a heuristic originally used to interpret the dynamics of complex ecosystems in response to disturbance and change. It is assumed that socially constructed governance systems go through similar phases (K, Ω [omega], α [alpha], r as evident in ecological adaptive cycles. Two key dimensions of change shaping the four phases of an adaptive cycle are the degree of connectedness and the range of potential in the system. Our purpose was to quantitatively assess the four phases of the adaptive cycle in a social system by measuring the potential and connectedness dimensions and their different levels in each of the four phases. We assessed these dimensions using quantitative data from content analysis of magazine articles describing the transition process of East German recreational fisheries governance after the fall of the Berlin Wall in 1989. This process was characterized by the discussion of two governance alternatives amendable for implementation: a central East German and a decentralized West German approach. Contrary to assumptions in the adaptive cycle heuristic, we were unable to identify the four phases of the adaptive cycle in our governance system based on quantitatively assessed levels of connectedness and potential alone. However, the insertion of in-group (East Germans and out-group (West Germans dimensions representing the two governance alternatives in our analysis enabled us to identify the specific time frames for all four phases of the adaptive cycle on a monthly basis. These findings suggest that an unmodified "figure-eight model" of the adaptive cycle may not necessarily hold in social systems. Inclusion of disciplinary theories such as intergroup relation theory will help in understanding adaptation processes in social systems.

  2. Life cycle assessment of a willow bioenergy cropping system

    International Nuclear Information System (INIS)

    Heller, M.C.; Keoleian, G.A.; Volk, Timothy A.

    2003-01-01

    The environmental performance of willow biomass crop production systems in New York (NY) is analyzed using life cycle assessment (LCA) methodology. The base-case, which represents current practices in NY, produces 55 units of biomass energy per unit of fossil energy consumed over the biomass crop's 23-year lifetime. Inorganic nitrogen fertilizer inputs have a strong influence on overall system performance, accounting for 37% of the non-renewable fossil energy input into the system. Net energy ratio varies from 58 to below 40 as a function of fertilizer application rate, but application rate also has implications on the system nutrient balance. Substituting inorganic N fertilizer with sewage sludge biosolids increases the net energy ratio of the willow biomass crop production system by more than 40%. While CO 2 emitted in combusting dedicated biomass is balanced by CO 2 adsorbed in the growing biomass, production processes contribute to the system's net global warming potential. Taking into account direct and indirect fuel use, N 2 O emissions from applied fertilizer and leaf litter, and carbon sequestration in below ground biomass and soil carbon, the net greenhouse gas emissions total 0.68 g CO 2 eq. MJ biomassproduced -1 . Site specific parameters such as soil carbon sequestration could easily offset these emissions resulting in a net reduction of greenhouse gases. Assuming reasonable biomass transportation distance and energy conversion efficiencies, this study implies that generating electricity from willow biomass crops could produce 11 units of electricity per unit of fossil energy consumed. Results form the LCA support the assertion that willow biomass crops are sustainable from an energy balance perspective and contribute additional environmental benefits

  3. Phase-changes in cell cycle of wound tissue irradiated with 5.21 Gy soft X-rays

    International Nuclear Information System (INIS)

    Liu Jianzhong; Zhou Yuanguo; Cheng Tianmin; Zhou Ping; Liu Xia; Li Ping

    2002-01-01

    Objective: To study the phase-changes in cell cycle of wound tissue which was locally irradiated with 5.21 Gy soft X-rays. Methods: Flow cytometry and PI staining were used to analyze cell cycle. Cell proliferation was determined with BrdU labeling. Results: During 3-9 days after irradiation, the percentage of the G 0 /G 1 phase cells in wound of the control side decreased while the percentage of S phase cells increased and reached the highest value on day 9. The percentage of G 2 /M phase cells also increased, and reached its peak on day 15. The percentage of G 0 /G 1 phase cell increased in wound of the irradiation side and was higher than that of the control wound, meanwhile the percentages of S and G 2 /M cells were significantly lower than those of the control wound. In the period of 12-22 days after wounding, the percentage of S phase cells increased and reached its peak value on the 22 th day. When most of cells were in S phase and arrested dramatically. Through the whole healing process, the percentage of G 2 /M in wound of the irradiation side was lower than that of the non-irradiated wound. The BrdU-positive cells were fibroblasts, endothelial cells and smooth muscle cells. Conclusion: These results suggest that G 1 block, S phase arrest, and switch of G 2 /M with suppression of mitotic activity of these cells are induced by local 5.21 Gy soft X-ray irradiation. Therefore, wound healing delay is induced partly by cell cycle arrest

  4. Analysis of limit cycling on a boiler feedwater control system

    International Nuclear Information System (INIS)

    Thomas, P.J.; Harrison, T.A.; Hollywell, P.D.

    1986-01-01

    During operation of the UKAEA Prototype Fast Reactor, it was found that oscillations sometimes occurred in the boiler feedwater systems. These were normally of relatively low amplitude, but led to the adoption of low controller gains so that control was rather slack. While control performance proved generally adequate for steady running, the lack of tight control of steam drum levels sometimes led to difficulties during periods when plant conditions were undergoing major change. The paper discusses the methods used to gain a full understanding of the phenomena occurring, and describes how that knowledge is being used to improve the control system so as to eliminate the limit cycling modes and ensure good control of steam drum levels. A noteworthy feature of the study was the use of two independent representations of plant behaviour: (i) a frequency response model, FWRFREQ, and (ii) a time-domain simulation model, PFRTDM. The simplified analysis of FWRFREQ proved to be of enormous value in identifying modes of system behaviour; PFRTDM was used as a detailed check on the accuracy and validity of the results obtained. (author)

  5. Control system to a Rankine cycle with a Tesla turbine using arduino

    International Nuclear Information System (INIS)

    Medeiros, Josenei G.; Guimaraes, Lamartine F.; Placco, Guilherme M.

    2013-01-01

    The thermal Rankine cycle is a thermodynamic cycle which converts heat in energy. This cycle occurs in steady state, in other words the cycle is a closed loop circuit with continuous feedback, which guarantees the reuse process one energy transformed in the various stages of the cycle. This cycle is used to drive a turbine type TESLA designed for the system. The objective of this work is to create the control and automation of this cycle using an micro-controlled system with Arduino that will hold the collection of sensors and the system will act to maintain the balance of the cycle causing it to behave continuously and with less interference from human operation for maintenance. Data will be collected and further processed, where it will display all the sensors and the situation of the actuators involved. Using Arduino system ensures the stability and reliability with a low cost of implementation

  6. Control system to a Rankine cycle with a Tesla turbine using arduino

    Energy Technology Data Exchange (ETDEWEB)

    Medeiros, Josenei G., E-mail: joseneigodoi@yahoo.com.br [Faculdade de Tecnologia Sao Francisco (FATESF), Jacarei, SP (Brazil); Guimaraes, Lamartine F.; Placco, Guilherme M., E-mail: guimarae@ieav.cta.br, E-mail: placco@ieav.cta.br [Instituto de Estudos Avancados (ENU/IEAv/DCTA), Sao Jose dos Campos, SP (Brazil). Departamento de Energia Nuclear

    2013-07-01

    The thermal Rankine cycle is a thermodynamic cycle which converts heat in energy. This cycle occurs in steady state, in other words the cycle is a closed loop circuit with continuous feedback, which guarantees the reuse process one energy transformed in the various stages of the cycle. This cycle is used to drive a turbine type TESLA designed for the system. The objective of this work is to create the control and automation of this cycle using an micro-controlled system with Arduino that will hold the collection of sensors and the system will act to maintain the balance of the cycle causing it to behave continuously and with less interference from human operation for maintenance. Data will be collected and further processed, where it will display all the sensors and the situation of the actuators involved. Using Arduino system ensures the stability and reliability with a low cost of implementation.

  7. Current status of feasibility studies on commercialized fuel cycle system for Fast Breeder Reactor

    International Nuclear Information System (INIS)

    Ojima, Hisao; Nagaoki, Yoshihiro

    2000-01-01

    A 'Feasibility Studies on Commercialized Fast Breeder Reactor Cycle System' is underway at the Japan Nuclear Cycle Development Institute (JNC). The study will select the promising concepts with their R and D tasks in order to commercialize the fast breeder reactor (FBR) cycle system. The feasibility studies (F/S) have to present surveyed and screened various relevant technologies, and defined the design requirement of the commercialized fuel cycle system for FBR. The promising technical options are being evaluated and conceptual designs are being examined. At the end of JFY2000, several candidate concepts of the commercialized FBR cycle system will be proposed. (author)

  8. Dual-objective optimization of organic Rankine cycle (ORC) systems using genetic algorithm: a comparison between basic and recuperative cycles

    Science.gov (United States)

    Hayat, Nasir; Ameen, Muhammad Tahir; Tariq, Muhammad Kashif; Shah, Syed Nadeem Abbas; Naveed, Ahmad

    2017-08-01

    Exploitation of low potential waste thermal energy for useful net power output can be done by manipulating organic Rankine cycle systems. In the current article dual-objectives (η_{th} and SIC) optimization of ORC systems [basic organic Rankine cycle (BORC) and recuperative organic Rankine cycle (RORC)] has been done using non-dominated sorting genetic algorithm (II). Seven organic compounds (R-123, R-1234ze, R-152a, R-21, R-236ea, R-245ca and R-601) have been employed in basic cycle and four dry compounds (R-123, R-236ea, R-245ca and R-601) have been employed in recuperative cycle to investigate the behaviour of two systems and compare their performance. Sensitivity analyses show that recuperation boosts the thermodynamic behaviour of systems but it also raises specific investment cost significantly. R-21, R-245ca and R-601 show attractive performance in BORC whereas R-601 and R-236ea in RORC. RORC, due to higher total investment cost and operation & maintenance costs, has longer payback periods as compared to BORC.

  9. Implementation of a Cost-Accounting System for Visibility of Weapon Systems Life-Cycle Costs

    National Research Council Canada - National Science Library

    Ugone, Mary

    2001-01-01

    ... costs through activity-based costing and management. The system must deliver timely, integrated data for management purposes to permit understanding of total weapon costs, provide a basis for estimating costs of future systems, and feed other tools for life-cycle cost management.

  10. Geomagnetic storms and their sources on the sun:the rising phase of the sunspot cycle

    Directory of Open Access Journals (Sweden)

    Takao Saito

    2013-03-01

    Full Text Available Solar phenomena, including solar flares and coronal holes, are considered in the context of a NEWS coordinate system, obtained by application of the heliographic and heliomagnetic coordinate systems to the solar latitude and longitude, respectively. By expressing the occurrence of solar phenomena in terms of NEWS coordinates, we discovered that solar flares tend to converge in the NE and SW quadrants of the solar disk, where they act as sources of sporadic storms. Meanwhile, coronal holes converge to solar longitudes of 0° and 180°, where they are sources of recurrent storms. Because of their concentration in the NE- and SW-quadrants, this correlation is referred to as the 'NEWS law'. The neutral line of the source surface shows a beautiful single wave in its declining phase, while it tends to show a double wave in the rising phase. Solar rotation numbers 2118 to 2119, where the neutral line exhibited two complicated asymmetric waves in both the N-S and S-W directions, were chosen for detailed analysis. Notwithstanding such an extremely complicated case, the NEWS law is satisfied when the double wave is separated into its two single-wave parts.

  11. Using single cell cultivation system for on-chip monitoring of the interdivision timer in Chlamydomonas reinhardtii cell cycle

    Directory of Open Access Journals (Sweden)

    Soloviev Mikhail

    2010-09-01

    Full Text Available Abstract Regulation of cell cycle progression in changing environments is vital for cell survival and maintenance, and different regulation mechanisms based on cell size and cell cycle time have been proposed. To determine the mechanism of cell cycle regulation in the unicellular green algae Chlamydomonas reinhardtii, we developed an on-chip single-cell cultivation system that allows for the strict control of the extracellular environment. We divided the Chlamydomonas cell cycle into interdivision and division phases on the basis of changes in cell size and found that, regardless of the amount of photosynthetically active radiation (PAR and the extent of illumination, the length of the interdivision phase was inversely proportional to the rate of increase of cell volume. Their product remains constant indicating the existence of an 'interdivision timer'. The length of the division phase, in contrast, remained nearly constant. Cells cultivated under light-dark-light conditions did not divide unless they had grown to twice their initial volume during the first light period. This indicates the existence of a 'commitment sizer'. The ratio of the cell volume at the beginning of the division phase to the initial cell volume determined the number of daughter cells, indicating the existence of a 'mitotic sizer'.

  12. Visualization of endothelial cell cycle dynamics in mouse using the Flt-1/eGFP-anillin system.

    Science.gov (United States)

    Herz, Katia; Becker, Alexandra; Shi, Chenyue; Ema, Masatsugo; Takahashi, Satoru; Potente, Michael; Hesse, Michael; Fleischmann, Bernd K; Wenzel, Daniela

    2018-05-01

    Endothelial cell proliferation is a key process during vascular growth but its kinetics could only be assessed in vitro or ex vivo so far. To enable the monitoring and quantification of cell cycle kinetics in vivo, we have generated transgenic mice expressing an eGFP-anillin construct under control of the endothelial-specific Flt-1 promoter. This construct labels the nuclei of endothelial cells in late G1, S and G2 phase and changes its localization during the different stages of M phase, thereby enabling the monitoring of EC proliferation and cytokinesis. In Flt-1/eGFP-anillin mice, we found eGFP + signals specifically in Ki67 + /PECAM + endothelial cells during vascular development. Quantification using this cell cycle reporter in embryos revealed a decline in endothelial cell proliferation between E9.5 to E12.5. By time-lapse microscopy, we determined the length of different cell cycle phases in embryonic endothelial cells in vivo and found a M phase duration of about 80 min with 2/3 covering karyokinesis and 1/3 cytokinesis. Thus, we have generated a versatile transgenic system for the accurate assessment of endothelial cell cycle dynamics in vitro and in vivo.

  13. Pyrogallol, ROS generator inhibits As4.1 juxtaglomerular cells via cell cycle arrest of G2 phase and apoptosis

    International Nuclear Information System (INIS)

    Park, Woo Hyun; Han, Yong Hwan; Kim, Suhn Hee; Kim, Sung Zoo

    2007-01-01

    Pyrogallol as a catechin compound has been employed as an O 2 · - generator and often used to investigate the role of ROS in the biological system. Here, we investigated the in vitro effect of pyrogallol on cell growth, cell cycle and apoptosis in As4.1 juxtaglomerular cells. Dose-dependent inhibition of cell growth was observed with IC 50 of about 60 μM for 48 h using MTT assay. Pyrogallol (100 μM) did not alter intracellular H 2 O 2 level and catalase activity, but increased the intracellular O 2 · - level and decreased SOD activity in As4.1 cells. DNA flow cytometric analysis indicated that 50 and 100 μM pyrogallol significantly increased G2 phase cells as compared with those of pyrogallol-untreated cells. Also, pyrogallol induced apoptosis as evidenced by flow cytometric detection of sub-G1 DNA content, annexin V binding assay and DAPI staining. This apoptosis process was accompanied with the loss of mitochondrial transmembrane potential (ΔΨ m ), Bcl-2 decrease, caspase-3 activation and PARP cleavage. Pan caspase inhibitor (Z-VAD) could significantly rescue As4.1 cells from pyrogallol-induced cell death. But, the inhibitors of caspase-3, caspase-8, and caspase-9 did not prevent apoptotic events in pyrogallol-treated As4.1 cells. Taken together, we have demonstrated that an ROS inducer, pyrogallol inhibits the growth of As4.1 JG cells via cell cycle arrest and apoptosis, and suggest that the compound exhibits an anti-proliferative efficacy on these cells

  14. Transfer of nuclides from the water phase to the sediments during normal and extraordinary hydrological cycles

    International Nuclear Information System (INIS)

    1985-07-01

    Atucha I and Atucha II nuclear power plants are located on the right margin of the Parana de las Palmas river. This river belongs to the Cuenca del Plata, whose 1982-1983 hydrologic cycle registered the greatest freshets of the century. Works and studies previously fixed had to be altered and investigations were adapted to the possibilities and the particular hydric conditions verified. Considerations on the transfer of nuclides between water and sediments are presented. The floods reduce the water-sediments contact time on the bed of the river. In outer areas, the waters labelled by the nuclear power plant effluent discharge favor the infiltration in alluvial soils, as well as the exchange with the sediments. The investigations carried out for the phase near to the discharge of liquid effluents (related to the critical group) made possible to prove the characteristics of the path of the liquid wastes released, the distribution coefficient and the fixation or penetrability of some nuclides in soils of the floody valley. In this manner, a balance of radioactive nuclides incorporated to soils and sediments from the neighbourhood of Atucha and the water-course of Parana de las Palmas river is obtained. The presence of 60 Co and 137 Cs in the floody soils on the right margin of this river was detected and measured during the greatest flood of the century. On the other hand, 144 Ce, 51 Cr, 106 Ru and 90 Sr have not been detected. The detection of artificial radioisotopes turns out to be impossible in normal hydrological years, even in the sorroundings of the nuclear power plant or the critical group (from the point of view of the surface waters, The Fishing Club, 3 km down stream). (M.E.L.) [es

  15. Diurnal Cycle of ITCZ Convection during the MJO Suppressed Phase in DYNAMO

    Science.gov (United States)

    Ciesielski, P. E.; Johnson, R. H.; Schubert, W. H.

    2017-12-01

    During the special observing period of the Dynamics of the MJO (DYNAMO) experiment, conducted over the Indian Ocean from 1 October to 30 November 2011, two sounding arrays - one north and one south of the equator, referred to here as the NSA and SSA, respectively - took 4-8 soundings/day. We augment this 3-h dataset with observations of radiation and rainfall to investigate the diurnal cycle of convection during the suppressed phase of the October MJO. During this 14-day period when convection was suppressed over the NSA but prominent over the SSA, the circulation over the sounding arrays could be characterized as a local Hadley cell embedded within a monsoonal flow. Strong rising motion was present within the ITCZ and compensating subsidence over the NSA. A prominent diurnal pulsing of this cell was observed, impacting conditions on both sides of the equator, with the cell running strongest in the early morning hours (05-08 LT) and notably weakening later in the day (17-20LT). The reduction in evening subsidence over the NSA may have assisted the moistening of the low to mid-troposphere there during the pre-onset stage of the MJO. Apparent heating Q1 within the ITCZ exhibits a diurnal evolution from early morning bottom-heavy profiles to weaker daytime top-heavy profiles. Making use of the weak temperature gradient approximation, results suggest that direct radiative effects played a dominant role in controlling diurnal variations of vertical motion and convection within the ITCZ while non-radiative processes were more prominent over the NSA.

  16. New Approaches in Reuseable Booster System Life Cycle Cost Modeling

    Science.gov (United States)

    Zapata, Edgar

    2013-01-01

    This paper presents the results of a 2012 life cycle cost (LCC) study of hybrid Reusable Booster Systems (RBS) conducted by NASA Kennedy Space Center (KSC) and the Air Force Research Laboratory (AFRL). The work included the creation of a new cost estimating model and an LCC analysis, building on past work where applicable, but emphasizing the integration of new approaches in life cycle cost estimation. Specifically, the inclusion of industry processes/practices and indirect costs were a new and significant part of the analysis. The focus of LCC estimation has traditionally been from the perspective of technology, design characteristics, and related factors such as reliability. Technology has informed the cost related support to decision makers interested in risk and budget insight. This traditional emphasis on technology occurs even though it is well established that complex aerospace systems costs are mostly about indirect costs, with likely only partial influence in these indirect costs being due to the more visible technology products. Organizational considerations, processes/practices, and indirect costs are traditionally derived ("wrapped") only by relationship to tangible product characteristics. This traditional approach works well as long as it is understood that no significant changes, and by relation no significant improvements, are being pursued in the area of either the government acquisition or industry?s indirect costs. In this sense then, most launch systems cost models ignore most costs. The alternative was implemented in this LCC study, whereby the approach considered technology and process/practices in balance, with as much detail for one as the other. This RBS LCC study has avoided point-designs, for now, instead emphasizing exploring the trade-space of potential technology advances joined with potential process/practice advances. Given the range of decisions, and all their combinations, it was necessary to create a model of the original model

  17. New Approaches in Reusable Booster System Life Cycle Cost Modeling

    Science.gov (United States)

    Zapata, Edgar

    2013-01-01

    This paper presents the results of a 2012 life cycle cost (LCC) study of hybrid Reusable Booster Systems (RBS) conducted by NASA Kennedy Space Center (KSC) and the Air Force Research Laboratory (AFRL). The work included the creation of a new cost estimating model and an LCC analysis, building on past work where applicable, but emphasizing the integration of new approaches in life cycle cost estimation. Specifically, the inclusion of industry processes/practices and indirect costs were a new and significant part of the analysis. The focus of LCC estimation has traditionally been from the perspective of technology, design characteristics, and related factors such as reliability. Technology has informed the cost related support to decision makers interested in risk and budget insight. This traditional emphasis on technology occurs even though it is well established that complex aerospace systems costs are mostly about indirect costs, with likely only partial influence in these indirect costs being due to the more visible technology products. Organizational considerations, processes/practices, and indirect costs are traditionally derived ("wrapped") only by relationship to tangible product characteristics. This traditional approach works well as long as it is understood that no significant changes, and by relation no significant improvements, are being pursued in the area of either the government acquisition or industry?s indirect costs. In this sense then, most launch systems cost models ignore most costs. The alternative was implemented in this LCC study, whereby the approach considered technology and process/practices in balance, with as much detail for one as the other. This RBS LCC study has avoided point-designs, for now, instead emphasizing exploring the trade-space of potential technology advances joined with potential process/practice advances. Given the range of decisions, and all their combinations, it was necessary to create a model of the original model

  18. Environmental impact assessment of a package type IFAS reactor during construction and operational phases: a life cycle approach.

    Science.gov (United States)

    Singh, Nitin Kumar; Singh, Rana Pratap; Kazmi, Absar Ahmad

    2017-05-01

    In the present study, a life cycle assessment (LCA) approach was used to analyse the environmental impacts associated with the construction and operational phases of an integrated fixed-film activated sludge (IFAS) reactor treating municipal wastewater. This study was conducted within the boundaries of a research project that aimed to investigate the implementation related challenges of a package type IFAS reactor from an environmental perspective. Along with the LCA results of the construction phase, a comparison of the LCA results of seven operational phases is also presented in this study. The results showed that among all the inputs, the use of stainless steel in the construction phase caused the highest impact on environment, followed by electricity consumption in raw materials production. The impact of the construction phase on toxicity impact indicators was found to be significant compared to all operational phases. Among the seven operational phases of this study, the dissolved oxygen phase III, having a concentration of ∼4.5 mg/L, showed the highest impact on abiotic depletion, acidification, global warming, ozone layer depletion, human toxicity, fresh water eco-toxicity, marine aquatic eco-toxicity, terrestrial eco-toxicity, and photochemical oxidation. However, better effluent quality in this phase reduced the eutrophication load on environment.

  19. [Integrated evaluation of circular agriculture system: a life cycle perspective].

    Science.gov (United States)

    Liang, Long; Chen, Yuan-Quan; Gao, Wang-Sheng

    2010-11-01

    For the point of view that recycling economy system is one of ways to achieve the low-carbon economy, we have made an evaluation on a typical circular agriculture duck industry in Hunan Province, China, through improving the framework of life cycle assessment (LCA). The analysis indicated that the consumption of non-renewable resources, land and water were 48.629 MJ, 2.36 m2 and 1 321.41 kg, while the potential greenhouse gas (GHGs), acidification, eutrophication, human toxicity, freshwater ecotoxicity and terrestrial ecotoxicity were 11 543.26 g (CO2 eq), 52.36g (SO2eq), 25.83g (PO4eq), 1.26, 60.74 and 24.65 g (1,4-DCBeq), respectively. The potential damage of aquatic eutrophication, freshwater ecotoxicity and terrestrial ecotoxicity was more serious than that of GHGs. Main results were following: i. the circular agricultural chain promoted the principle of "moderate circulation", which based on the traditional production methods; ii. circular agriculture could not blindly pursue low carbon development. Instead, soil and biological carbon sequestration should be considered, in addition to reducing carbon emissions; iii. circular economy and circular agriculture should take other potential environmental impacts into account such as acidification, eutrophication and ecotoxicity,with the exception to carbon emissions,to developed integrated system assessment; iv. LCA could provide a comprehensive assessment of circular agriculture, and it was worth of further study.

  20. The clock is ticking. Ageing of the circadian system: From physiology to cell cycle.

    Science.gov (United States)

    Terzibasi-Tozzini, Eva; Martinez-Nicolas, Antonio; Lucas-Sánchez, Alejandro

    2017-10-01

    The circadian system is the responsible to organise the internal temporal order in relation to the environment of every process of the organisms producing the circadian rhythms. These rhythms have a fixed phase relationship among them and with the environment in order to optimise the available energy and resources. From a cellular level, circadian rhythms are controlled by genetic positive and negative auto-regulated transcriptional and translational feedback loops, which generate 24h rhythms in mRNA and protein levels of the clock components. It has been described about 10% of the genome is controlled by clock genes, with special relevance, due to its implications, to the cell cycle. Ageing is a deleterious process which affects all the organisms' structures including circadian system. The circadian system's ageing may produce a disorganisation among the circadian rhythms, arrhythmicity and, even, disconnection from the environment, resulting in a detrimental situation to the organism. In addition, some environmental conditions can produce circadian disruption, also called chronodisruption, which may produce many pathologies including accelerated ageing. Finally, some strategies to prevent, palliate or counteract chronodisruption effects have been proposed to enhance the circadian system, also called chronoenhancement. This review tries to gather recent advances in the chronobiology of the ageing process, including cell cycle, neurogenesis process and physiology. Copyright © 2017 Elsevier Ltd. All rights reserved.

  1. Analysis of human mammary fibroadenoma by Ki-67 index in the follicular and luteal phases of menstrual cycle.

    Science.gov (United States)

    Rego, M F; Navarrete, M A L H; Facina, G; Falzoni, R; Silva, R; Baracat, E C; Nazario, A C P

    2009-04-01

    Fibroadenoma is the most common benign mammary condition among women aged 35 or younger. Expression of Ki-67 antigen has been used to compare proliferative activity of mammary fibroadenoma epithelium in the follicular and luteal phases of the menstrual cycle. Ninety eumenorrheic women were selected for tumour excision; they were assigned to either of the two groups, according to their phase of menstrual cycle. At the end of the study, 75 patients with 87 masses were evaluated by epithelial cell Ki-67 expression, blind (no information given concerning group to which any lesion belonged). Both groups were found to be homogeneous relative to age, menarche, body mass index, previous gestation, parity, breastfeeding, number of fibroadenomas, family history of breast cancer and tabagism. Median tumour size was 2.0 cm and no relationship between proliferative activity and nodule diameter was observed. No typical pattern was observed in the expression of Ki-67 in distinct nodules of the same patient. Average values for expression of Ki-67 (per 1000 epithelial cells) in follicular and luteal phases were 27.88 and 37.88, respectively (P = 0.116). Our findings revealed that proliferative activities in the mammary fibroadenoma epithelium did not present a statistically significant difference in the follicular and luteal phases. The present study contributes to clarifying that fibroadenoma is a neoplasm and does not undergo any change in the proliferative activity during the menstrual cycle.

  2. Administration of single-dose GnRH agonist in the luteal phase in ICSI cycles: a meta-analysis

    Directory of Open Access Journals (Sweden)

    Oliveira João

    2010-09-01

    Full Text Available Abstract Background The effects of gonadotrophin-releasing hormone agonist (GnRH-a administered in the luteal phase remains controversial. This meta-analysis aimed to evaluate the effect of the administration of a single-dose of GnRH-a in the luteal phase on ICSI clinical outcomes. Methods The research strategy included the online search of databases. Only randomized studies were included. The outcomes analyzed were implantation rate, clinical pregnancy rate (CPR per transfer and ongoing pregnancy rate. The fixed effects model was used for odds ratio. In all trials, a single dose of GnRH-a was administered at day 5/6 after ICSI procedures. Results All cycles presented statistically significantly higher rates of implantation (P Conclusions These findings demonstrate that the luteal-phase single-dose GnRH-a administration can increase implantation rate in all cycles and CPR per transfer and ongoing pregnancy rate in cycles with GnRH antagonist ovarian stimulation protocol. Nevertheless, by considering the heterogeneity between the trials, it seems premature to recommend the use of GnRH-a in the luteal phase. Additional randomized controlled trials are necessary before evidence-based recommendations can be provided.

  3. Phase Change Energy Storage Material Suitable for Solar Heating System

    Science.gov (United States)

    Li, Xiaohui; Li, Haihua; Zhang, Lihui; Liu, Zhenfa

    2018-01-01

    Differential scanning calorimetry (DSC) was used to investigate the thermal properties of palmitic acid, myristic acid, laurel acid and the binary composite of palmitic/laurel acid and palmitic/myristic acid. The results showed that the phase transition temperatures of the three monomers were between 46.9-65.9°C, and the latent heats were above 190 J/g, which could be used as solar energy storage material. When the mass ratio of Palmitic acid and myristic was 1:1, the eutectic mixture could be formed. The latent heat of the eutectic mixture was 186.6 J/g, the melting temperature and the solidification temperature was 50.6°C and 43.8°C respectively. The latent heat of phase change and the melting temperature had not obvious variations after 400 thermal cycles, which proved that the binary composite had good thermal stability and was suitable for solar floor radiant heating system.

  4. Phase coexistence and line tension in ternary lipid systems

    NARCIS (Netherlands)

    Idema, T.; Leeuwen, van J.M.J.; Storm, C.

    2009-01-01

    The ternary system consisting of cholesterol, a saturated lipid, and an unsaturated one exhibits a rich phase behavior with multiple phase coexistence regimes. Remarkably, phase separation even occurs when each of the three binary systems consisting of two of these components is a uniform mixture.

  5. Circadian Rhythm Management System, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — The value of measuring sleep-wake cycles is significantly enhanced by measuring other physiological signals that depend on circadian rhythms (such as heart rate and...

  6. System Losses Study - FIT (Fuel-cycle Integration and Tradeoffs)

    Energy Technology Data Exchange (ETDEWEB)

    Steven J. Piet; Nick R. Soelberg; Samuel E. Bays; Robert S. Cherry; Denia Djokic; Candido Pereira; Layne F. Pincock; Eric L. Shaber; Melissa C. Teague; Gregory M. Teske; Kurt G. Vedros

    2010-09-01

    This team aimed to understand the broad implications of changes of operating performance and parameters of a fuel cycle component on the entire system. In particular, this report documents the study of the impact of changing the loss of fission products into recycled fuel and the loss of actinides into waste. When the effort started in spring 2009, an over-simplified statement of the objective was “the number of nines” – how would the cost of separation, fuel fabrication, and waste management change as the number of nines of separation efficiency changed. The intent was to determine the optimum “losses” of TRU into waste for the single system that had been the focus of the Global Nuclear Energy Program (GNEP), namely sustained recycle in burner fast reactors, fed by transuranic (TRU) material recovered from used LWR UOX-51 fuel. That objective proved to be neither possible (insufficient details or attention to the former GNEP options, change in national waste management strategy from a Yucca Mountain focus) nor appropriate given the 2009-2010 change to a science-based program considering a wider range of options. Indeed, the definition of “losses” itself changed from the loss of TRU into waste to a generic definition that a “loss” is any material that ends up where it is undesired. All streams from either separation or fuel fabrication are products; fuel feed streams must lead to fuels with tolerable impurities and waste streams must meet waste acceptance criteria (WAC) for one or more disposal sites. And, these losses are linked in the sense that as the loss of TRU into waste is reduced, often the loss or carryover of waste into TRU or uranium is increased. The effort has provided a mechanism for connecting these three Campaigns at a technical level that had not previously occurred – asking smarter and smarter questions, sometimes answering them, discussing assumptions, identifying R&D needs, and gaining new insights. The FIT model has been a

  7. Presence of the acute phase protein, bikunin, in the endometrium of gilts during estrous cycle and early pregnancy.

    Science.gov (United States)

    Hettinger, A M; Allen, M R; Zhang, B R; Goad, D W; Malayer, J R; Geisert, R D

    2001-08-01

    Noninvasive, epitheliochorial placental attachment in the pig is regulated through endometrial production of protease inhibitors. The objective of the present study was to determine if the light-chain serine protease inhibitor of the inter-alpha-trypsin inhibitor family, bikunin, is produced by the porcine endometrium during the estrous cycle and early pregnancy. Western blot analysis revealed the presence of bikunin in uterine flushings of gilts collected during the luteal phase of the estrous cycle and early pregnancy (Days 12-18). However, bikunin unbound to the inter-alpha-trypsin heavy chains was detected only in endometrial explant culture medium obtained from estrus and pregnant (Days 12, 15, and 18) gilts. Endometrial bikunin gene expression was lowest on Day 10 of the estrous cycle and pregnancy, followed by a 30- to 77-fold increase on Day 15 of the estrous cycle and pregnancy. Bikunin gene expression decreased on Day 18 of the estrous cycle, whereas endometrial bikunin gene expression continued to increase in pregnant gilts. Bikunin mRNA was localized to the uterine glands between Days 15 and 18 of the estrous cycle and pregnancy. In addition to its role as a protease inhibitor, bikunin functions in stabilization of the extracellular matrix, which suggests that bikunin could be involved with facilitating placental attachment to the uterine epithelial surface in the pig.

  8. Development of a control system for compression and expansion cycles of critical valve for high vacuum systems

    Energy Technology Data Exchange (ETDEWEB)

    Agarwal, Jyoti, E-mail: jagarwal@ipr.res.in; Sharma, H.; Patel, Haresh; Gangradey, R.; Lambade, Vrushabh

    2016-11-15

    Highlights: • Control system with feedback loop of pressure gauge is developed for measuring the life cycle of vacuum isolation valve. • GUI based software developed for easy use and handling of control system. • Control system tested with an experiment showcasing the capability of the control system. • Control system can operate valve based on pressure inside the chamber, which helps to know the degradation of sealing capabilities of valve. • Control system can monitor the total closing and opening time of valve, cycles and pressure inside the vessel. - Abstract: A control system with feedback loop is designed, developed and tested to monitor the life cycles of the axial valve and bellows used in vacuum valves. The control system monitors number of compression cycles of any bellow or closing and opening cycle of a valve. It also interfaces vacuum gauges or pressure gauges to get pressure values inside the system. To find life cycle of valve, the developed control and monitoring system is integrated with an axial valve experimental test set up. In this system, feedback from the vacuum gauge attached to valve enclosure, is given and the life cycle test is automated. This paper describes the control and monitoring system in details and briefs the experiment carried out for valve life cycle. The same system can be used for life cycle estimate for bellows. A suitable GUI is also developed to control the function of the components and resister the number of cycles.

  9. Nitrogen cycling in an integrated biomass for energy system

    International Nuclear Information System (INIS)

    Moorhead, K.K.

    1986-01-01

    A series of experiments was conducted to evaluate N cycling in three components of an integrated biomass for energy system, i.e. water hyacinth production, anaerobic digestion in hyacinth biomass, and recycling of digester effluent and sludge. Plants assimilated 50 to 90% of added N in hyacinth production systems. Up to 28% of the total plant N was contained in hyacinth detritus. Nitrogen loading as plant detritus into hyacinth ponds was 92 to 148 kg N ha -1 yr -1 . Net mineralization of plant organic 15 N during anaerobic digestion was 35 and 70% for water hyacinth plants with low and high N content, respectively. Approximately 20% of the 15 N was recovered in the digested sludge while the remaining 15 N was recovered in the effluent. Water hyacinth growth in digester effluents was affected by electrical conductivity and 15 NH 4 + -N concentration. Addition of water hyacinth biomass to soil resulted in decomposition of 39 to 50% of added C for fresh plant biomass and 19 to 23% of added C for digested biomass sludge. Only 8% of added 15 N in digested sludges was mineralized to 15 NO 3 - -N despite differences in initial N content. In contrast, 3 and 33% of added 15 N in fresh biomass with low and high N content, respectively, was recovered as 15 NO 3 - -N. Total 15 N recovery after anaerobic digestion ranged from 70 to 100% of the initial plant biomass 15 N. Total N recovery by sludge and effluent recycling in the integrated biomass for energy system was 48 to 60% of the initial plant biomass 15 N

  10. Monitored Retrievable Storage conceptual system study: open cycle vault

    International Nuclear Information System (INIS)

    Smith, R.I.

    1983-11-01

    This report provides a modified description of the Open Cycle Vault Storage Concept which meets a specified set of requirements; an estimate of the costs of construction, operation, and decommissioning of the concepts; the costs required to expand the facility throughput and storage capability; and the life-cycle costs of the facility. 11 references, 23 figures, 35 tables

  11. S-phase-dependent cell cycle disturbances caused by Aleutian mink disease parvovirus

    DEFF Research Database (Denmark)

    Oleksiewicz, M.B.; Alexandersen, Søren

    1997-01-01

    We examined replication of the autonomous parovirus Aleutian mink disease parovirus (ADV) in relation to cell cycle progression of permissive Crandell feline kidney (CRFK) cells. Flow cytometric analysis showed that ADV caused a composite, binary pattern of cell cycle arrest. ADV-induced cell cyc...

  12. Application of Remote Condition Monitoring in Different Rolling Stock Life Cycle Phases

    NARCIS (Netherlands)

    Mooren Ceng, F.P.J.H.; van Dongen, Leonardus Adriana Maria

    2013-01-01

    NedTrain is the Netherlands Railway's subsidiary responsible for rolling stock maintenance. The life cycle is 30-40 years where the asset condition is maintained to meet it's performance requirements and is enhanced to meet the customer expectations through it's life. The life cycle costs are

  13. Phase locking and multiple oscillating attractors for the coupled mammalian clock and cell cycle

    NARCIS (Netherlands)

    C. Feillet (Céline); C.A. Krusche; F. Tamanini (Filippo); R. Janssens (Roel); R.A. Downey (Roger); P. Martin (Patrick); J.L. Teboul (Jean Louis); S. Saito (Seiji); F.A. Lévi (Francis); T. Bretschneider (Till); G.T.J. van der Horst (Gijsbertus); F. Delaunay (Franck); D.A. Rand (David)

    2014-01-01

    textabstractDaily synchronous rhythms of cell division at the tissue or organism level are observed in many species and suggest that the circadian clock and cell cycle oscillators are coupled. For mammals, despite known mechanistic interactions, the effect of such coupling on clock and cell cycle

  14. Implementing Effective Mission Systems Engineering Practices During Early Project Formulation Phases

    Science.gov (United States)

    Moton, Tryshanda

    2016-01-01

    Developing and implementing a plan for a NASA space mission can be a complicated process. The needs, goals, and objectives of any proposed mission or technology must be assessed early in the Project Life Cycle. The key to successful development of a space mission or flight project is the inclusion of systems engineering in early project formulation, namely during Pre-phase A, Phase A, and Phase B of the NASA Project Life Cycle. When a space mission or new technology is in pre-development, or "pre-Formulation", feasibility must be determined based on cost, schedule, and risk. Inclusion of system engineering during project formulation is key because in addition to assessing feasibility, design concepts are developed and alternatives to design concepts are evaluated. Lack of systems engineering involvement early in the project formulation can result in increased risks later in the implementation and operations phases of the project. One proven method for effective systems engineering practice during the pre-Formulation Phase is the use of a mission conceptual design or technology development laboratory, such as the Mission Design Lab (MDL) at NASA's Goddard Space Flight Center (GSFC). This paper will review the engineering process practiced routinely in the MDL for successful mission or project development during the pre-Formulation Phase.

  15. A brief review study of various thermodynamic cycles for high temperature power generation systems

    International Nuclear Information System (INIS)

    Yu, Si-Cong; Chen, Lin; Zhao, Yan; Li, Hong-Xu; Zhang, Xin-Rong

    2015-01-01

    Highlights: • Various high temperature power generation cycles for are reviewed and analyzed. • The operating temperature is higher than 700 K for high temperature power systems. • Thermodynamic cycle model study and working fluid choices are discussed. • Characteristics and future developments of high temperature cycles are presented and compared. - Abstract: This paper presents a review of the previous studies and papers about various thermodynamic cycles working for high temperature power generation procedures, in these cycles the highest temperature is not lower than 700 K. Thermodynamic cycles that working for power generation are divided into two broad categories, thermodynamic cycle model study and working fluid analysis. Thermodynamic cycle contains the simple cycle model and the complex cycle model, emphasis has been given on the complex thermodynamic cycles due to their high thermal efficiencies. Working fluids used for high temperature thermodynamic cycles is a dense gas rather than a liquid. A suitable thermodynamic cycle is crucial for effectively power generation especially under the condition of high temperature. The main purpose is to find out the characteristics of various thermodynamic cycles when they are working in the high temperature region for power generation. As this study shows, combined cycles with both renewable and nonrenewable energies as the heat source can show good performance

  16. Dynamic behavior of Rankine cycle system for waste heat recovery of heavy duty diesel engines under driving cycle

    International Nuclear Information System (INIS)

    Xie, Hui; Yang, Can

    2013-01-01

    Highlights: • Waste heat recovery behavior of the RCS during driving cycle was investigated. • Four operating modes were defined to describe the operating process of the RCS under driving cycle. • The operating mode switching is the crucial reason for on-road inefficiency. • The dry and isentropic fluids are superior to the wet ones on the adaptability to unsteady ExGE. • The effects of the vapor parameters on RCT-E and power mode percentage are opposite. - Abstract: The RCS (Rankine cycle system) used to recover the WHE (waste heat energy) from engines has been regarded as one of the most potential ways of achieving higher efficiency. However, it is of great challenge to keep the RCS still in good performance under driving cycle. This paper tries to reveal and explain its on-road inefficiency. The operating process of the RCS under driving cycle was analyzed in advance. Afterwards, four basic operating modes were defined, including startup mode, turbine turning mode, power mode and protection mode. Then, a RCS model was established and operating performances of the RCS under an actual driving cycle were discussed based on this model. The results indicate that the on-road RCS-E (Rankine cycle system efficiency) is as low as 3.63%, which is less than half of the design RCS-E (7.77%) at the rated operating point. Despite the inevitable vapor state fluctuation, it is the operating mode switching during the driving cycle that leads to the on-road inefficiency. Further investigations indicate that the expander safety temperature and its safety margin affected by the working fluids, designed superheat degree and evaporating pressure are the main factors determining the operating mode switching. Finally, the effects of the working fluids, designed superheat degree and evaporating pressure on the operating mode switching and RC (Rankine cycle) efficiencies were profoundly investigated. The study shows that the dry and isentropic fluids are superior to the wet

  17. Analysis of environmental impact phase in the life cycle of a nuclear power plant

    International Nuclear Information System (INIS)

    Hernandez del M, C.

    2015-01-01

    The life-cycle analysis covers the environmental aspects of a product throughout its life cycle. The focus of this study was to apply a methodology of life-cycle analysis for the environmental impact assessment of a nuclear power plant by analyzing international standards ISO 14040 and 14044. The methodology of life-cycle analysis established by the ISO 14044 standard was analyzed, as well as the different impact assessment methodologies of life cycle in order to choose the most appropriate for a nuclear power plant; various tools for the life-cycle analysis were also evaluated, as is the use of software and the use of databases to feed the life cycle inventory. The functional unit chosen was 1 KWh of electricity, the scope of analysis ranging from the construction and maintenance, disposal of spent fuel to the decommissioning of the plant, the manufacturing steps of the fuel were excluded because in Mexico is not done this stage. For environmental impact assessment was chosen the Recipe methodology which evaluates up to 18 impact categories depending on the project. In the case of a nuclear power plant were considered only categories of depletion of the ozone layer, climate change, ionizing radiation and formation of particulate matter. The different tools for life-cycle analysis as the methodologies of impact assessment of life cycle, different databases or use of software have been taken according to the modeling of environmental sensitivities of different regions, because in Mexico the methodology for life-cycle analysis has not been studied and still do not have all the tools necessary for the evaluation, so the uncertainty of the data supplied and results could be higher. (Author)

  18. Effect of menstrual cycle phase on the concentration of individual carotenoids in lipoproteins of premenopausal women: a controlled dietary study.

    Science.gov (United States)

    Forman, M R; Johnson, E J; Lanza, E; Graubard, B I; Beecher, G R; Muesing, R

    1998-01-01

    Because premenopausal women experience cyclic fluctuations of plasma carotenoids and their lipoprotein carriers, it is hypothesized that carotenoid concentrations in lipoprotein fractions fluctuate by phase of the menstrual cycle. Nine women ate a standard set of carotenoid-rich foods daily for two cycles under isoenergetic conditions. In the second cycle, hormones and carotenoids in lipoprotein fractions were measured in the early and late follicular and luteal phases. alpha-Carotene concentrations in the LDL fraction were lower in the early than in the late follicular phase (P = 0.03) on the basis of regression analysis. beta-carotene concentrations in the LDL fraction and the HDL2 subfraction were higher in the late follicular than in the luteal phase (P = 0.02 and P = 0.04, respectively). Lutein/zeaxanthin concentrations in the LDL and HDL fractions were higher in the late follicular than in the luteal phase (P = 0.03 and P = 0.02, respectively). In each phase, 80% of alpha-carotene, 82% of beta-carotene, 85% of lycopene, and 64% of lutein/zeaxanthin were distributed in the LDL fraction. Among the hydrocarbon cartenoids, 18% of alpha-carotene and of beta-carotene and 13% of lycopene were distributed in the HDL fraction, with slightly more in the HDL2 than in the HDL3 subfraction. In contrast 34% of lutein/zeaxanthin was distributed in the HDL fraction with more concentrated in the HDL3 than in the HDL2 subfraction. Less than 4% of any carotenoid was found in the VLDL + IDL (intermediate-density-lipoprotein) fractions. Thus, the hydrocarbon carotenoids were highly concentrated in the LDL fraction and xanthophyll was more evenly distributed in the LDL and HDL fractions. The cyclic fluctuations of these carotenoids in lipoprotein fractions add another dimension to the understanding of their transport and physiologic function.

  19. Exergy analysis of helium liquefaction systems based on modified Claude cycle with two-expanders

    Science.gov (United States)

    Thomas, Rijo Jacob; Ghosh, Parthasarathi; Chowdhury, Kanchan

    2011-06-01

    Large-scale helium liquefaction systems, being energy-intensive, demand judicious selection of process parameters. An effective tool for design and analysis of thermodynamic cycles for these systems is exergy analysis, which is used to study the behavior of a helium liquefaction system based on modified Claude cycle. Parametric evaluation using process simulator Aspen HYSYS® helps to identify the effects of cycle pressure ratio and expander flow fraction on the exergetic efficiency of the liquefaction cycle. The study computes the distribution of losses at different refrigeration stages of the cycle and helps in selecting optimum cycle pressures, operating temperature levels of expanders and mass flow rates through them. Results from the analysis may help evolving guidelines for designing appropriate thermodynamic cycles for practical helium liquefaction systems.

  20. Power and phase monitoring system for the lower hybrid phased array heating system on ATC machine

    International Nuclear Information System (INIS)

    Reed, B.W.

    1975-01-01

    A four waveguide phased array slow wave structure has been constructed to couple microwave energy into plasma in the ATC Tokamac at Princeton. Theory has indicated that the coupling of power into the plasma column is a strong function of the imposed fourier spectrum at the antenna aperture. To optimize heating, and to verify theoretical results, a precision amplitude and phase monitoring system has been designed and constructed. The system data output is routed to an IBM 1800 computer where the fourier spectrum in n/sub parallel/ space is computed for discrete increments of time during an RF pulse. Computer output data is used to update the adjustment of transmission line parameters in between pulses

  1. System For Characterizing Three-Phase Brushless dc Motors

    Science.gov (United States)

    Howard, David E.; Smith, Dennis A.

    1996-01-01

    System of electronic hardware and software developed to automate measurements and calculations needed to characterize electromechanical performances of three-phase brushless dc motors, associated shaft-angle sensors needed for commutation, and associated brushless tachometers. System quickly takes measurements on all three phases of motor, tachometer, and shaft-angle sensor simultaneously and processes measurements into performance data. Also useful in development and testing of motors with not only three phases but also two, four, or more phases.

  2. A safety assessment of the SEAFP fuel cycle systems

    International Nuclear Information System (INIS)

    Natalizio, A.; Kalyanam, K.; Ciattaglia, S.; Pace, L. di

    1995-01-01

    CFFTP and ENEA participated in a joint safety assessment of the fuel cycle design developed for the SEAFP fusion power reactor study (SEAFP: Safety and Environmental Assessment of Fusion Power). The assessment considered both conventional (deflagation/detonation) and radioactive hazards associated with the handling of significant quantities of hydrogen isotopes (H, D and T). Accordingly, the assessment focused on systems or equipment where either the flow rate, or inventory, of hydrogen isotopes was large. A systematic and thorough assessment of initiating events that can lead to an accidental release of tritium into the environment was the first step of the analysis process. This review demonstrated that, in all cases, there are at least two lines of defence available for mitigating the consequences of such accidents -i.e., secondary confinement (glove box, second pipe, caisson, etc.) and the building confinement, backed-up by an air detritiation capability. Therefore, large releases of tritium to the environment will occur only at very low frequencies. (orig.)

  3. Full fuel-cycle comparison of forklift propulsion systems

    International Nuclear Information System (INIS)

    Gaines, L.L.; Elgowainy, A.; Wang, M.Q.

    2008-01-01

    Hydrogen has received considerable attention as an alternative to fossil fuels. The U.S. Department of Energy (DOE) investigates the technical and economic feasibility of promising new technologies, such as hydrogen fuel cells. A recent report for DOE identified three near-term markets for fuel cells: (1) Emergency power for state and local emergency response agencies, (2) Forklifts in warehousing and distribution centers, and (3) Airport ground support equipment markets. This report examines forklift propulsion systems and addresses the potential energy and environmental implications of substituting fuel-cell propulsion for existing technologies based on batteries and fossil fuels. Industry data and the Argonne Greenhouse Gases, Regulated Emissions, and Energy Use in Transportation (GREET) model are used to estimate full fuel-cycle emissions and use of primary energy sources, back to the primary feedstocks for fuel production. Also considered are other environmental concerns at work locations. The benefits derived from using fuel-cell propulsion are determined by the sources of electricity and hydrogen. In particular, fuel-cell forklifts using hydrogen made from the reforming of natural gas had lower impacts than those using hydrogen from electrolysis

  4. Full fuel-cycle comparison of forklift propulsion systems.

    Energy Technology Data Exchange (ETDEWEB)

    Gaines, L. L.; Elgowainy, A.; Wang, M. Q.; Energy Systems

    2008-11-05

    Hydrogen has received considerable attention as an alternative to fossil fuels. The U.S. Department of Energy (DOE) investigates the technical and economic feasibility of promising new technologies, such as hydrogen fuel cells. A recent report for DOE identified three near-term markets for fuel cells: (1) Emergency power for state and local emergency response agencies, (2) Forklifts in warehousing and distribution centers, and (3) Airport ground support equipment markets. This report examines forklift propulsion systems and addresses the potential energy and environmental implications of substituting fuel-cell propulsion for existing technologies based on batteries and fossil fuels. Industry data and the Argonne Greenhouse Gases, Regulated Emissions, and Energy Use in Transportation (GREET) model are used to estimate full fuel-cycle emissions and use of primary energy sources, back to the primary feedstocks for fuel production. Also considered are other environmental concerns at work locations. The benefits derived from using fuel-cell propulsion are determined by the sources of electricity and hydrogen. In particular, fuel-cell forklifts using hydrogen made from the reforming of natural gas had lower impacts than those using hydrogen from electrolysis.

  5. System, structure, and component evaluation for life-cycle management

    International Nuclear Information System (INIS)

    Hanley, N.E.; Banerjee, A.K.; Woods, P.B.; Perrin, J.S.; Marian, F.A.

    1992-01-01

    In recent years, many nuclear organizations and utilities have studied the possibility of extending the service life of nuclear power plants beyond the original license period. From these studies, recommendations have resulted for maintaining the option of future decisions concerning operating license renewal. Several of the recommendations are considered beneficial to the management and operation of nuclear plants in meeting many of their near-term goals. In 1986, Public Service Electric and Gas (PSE and G) concluded that a full-scale nuclear plant license renewal program for their Salem 1 and 2 and Hope Creek nuclear stations was not cost-effective at that time. Rather, it would be better served if the nuclear plant life extension (PLEX) option were maintained for future consideration. To help plan for the life extension option, a strategic 5-yr life cycle management (LCM) program was begun. In support of the LCM program, evaluations for the following Salem structures and components were performed: (1) intake structures, (2) reactor vessel support, (3) containment liner, and (4) containment structure (below grade). This paper discusses the systems, structures, and components (SSC) evaluation methodology and, as an example, discusses the evaluation performed for reactor vessel support

  6. Rapid Cycle Amine (RCA) 3.0 System Development

    Science.gov (United States)

    Chullen, Cinda; Campbell, Colin; Papale, William; Hawes, Kevin; Wichowski, Robert

    2015-01-01

    The Rapid Cycle Amine (RCA) 3.0 system is currently under development by NASA, the Lyndon B. Johnson Space Center (JSC) in conjunction with United Technologies Corporation Aerospace Systems (UTAS). The RCA technology is a new carbon dioxide (CO2) and humidity removal system that has been baselined for the Advanced Extravehicular Mobility Unit (AEMU) Portable Life Support System. The evolution of the RCA development has progressed through several iterations of technology readiness levels including RCA 1.0, RCA 2.0, and RCA 3.0 test articles. The RCA is an advancement over currently technologies due to its unique regeneration capability. The RCA is capable of simultaneously removing CO2 and humidity from an influent air steam and subsequent regeneration when exposed to a vacuum source. The RCA technology uses two solid amine sorbent beds in an alternating fashion to adsorb CO2 and water (uptake mode) and desorb CO2 and water (regeneration mode) at the same time. The two beds operate in an efficient manner so that while one bed is in the uptake mode, the other is in the regeneration mode, thus continuously providing an on-service sorbent bed by which CO2 and humidity may be removed. The RCA 2.0 and 3.0 test articles were designed with a novel valve assembly which allows for switching between uptake and regeneration modes with only one moving part while minimizing gas volume losses to the vacuum source by means of an internal pressure equalization step during actuation. The RCA technology also is low power, small, and has performed extremely well in all development testing thus far. A final design was selected for the RCA 3.0, fabricated, assembled, and performance tested in 2014 with delivery to NASAJSC in January 2015. This paper will provide an overview on the RCA 3.0 system design and results of pre-delivery testing with references to the development of RCA 1.0 and RCA 2.0.

  7. Effect of duration of the GnRH agonists in the luteal phase in the outcome of assisted reproduction cycles.

    Science.gov (United States)

    Geber, Selmo; Sampaio, Marcos

    2013-06-01

    The effect of long-acting GnRHa, in the luteal phase, during ART cycles varies from one patient to another. The aim of this study was to evaluate whether the effect of long-acting GnRHa in the luteal phase, in ART cycles, affects pregnancy rates according to the duration of its action in such phase. This is a retrospective study of 367 patients submitted to ovulation induction for in vitro fertilization/intracytoplasmic sperm injection procedures that used long-acting depot GnRHa for pituitary suppression. Patients were stratified according to the period of action of the agonist in the luteal phase: group 1, ≤ 6 days; group 2, 7 to 12 days; and group 3, >12 days. The following variables were analyzed: ovarian response, age, infertility causes and pregnancy rates. Group 1 (n = 53) had a mean age of 33.8 ± 4.55 years (23-44 years) and a pregnancy rate of 45.2%. In group 2 (n = 118), mean age was 33.7 ± 4.5 years (24-44 years) and the pregnancy rate was 38.9%. In group 3 (n = 196), mean age was 33.7 ± 4.4 years (23-43 years) and the pregnancy rate was 47.4%. Regardless of the duration of depot GnRHa action in the luteal phase, no significant association with pregnancy rates was found.

  8. Effects of ACTH on corticosteroid and progesterone levels in female baboons depending on the phase of the menstrual cycle

    International Nuclear Information System (INIS)

    Todua, T.N.; Goncharov, N.P.; Katsiya, G.V.; Lapin, B.A.; Vorontsov, V.I.

    1986-01-01

    To study the effect of ACTH on the endocrine function of steroid producing glands depending on the level of sex hormones in the body, a comparative study of the dynamics of steroid hormones in the follicular and luteal phases of the menstrual cycle in response to a standard does of ACTH was undertaken in experiments on hamadryad baboons. Concentrations of corticosterone, 11-deoxycortisol, and progesterone were determined in duplicate samples of plasma by radioimmunoassay. It is shown that the sensitivity of the adrenals to a single injection of ACTH is independent of the phase of the menstrual cycle and the inhibitory effects of ACTH on progesterone secretion is exhibited only in the presence of an actively functioning corpus luteus of the ovary

  9. Effects of ACTH on corticosteroid and progesterone levels in female baboons depending on the phase of the menstrual cycle

    Energy Technology Data Exchange (ETDEWEB)

    Todua, T.N.; Goncharov, N.P.; Katsiya, G.V.; Lapin, B.A.; Vorontsov, V.I.

    1986-01-01

    To study the effect of ACTH on the endocrine function of steroid producing glands depending on the level of sex hormones in the body, a comparative study of the dynamics of steroid hormones in the follicular and luteal phases of the menstrual cycle in response to a standard does of ACTH was undertaken in experiments on hamadryad baboons. Concentrations of corticosterone, 11-deoxycortisol, and progesterone were determined in duplicate samples of plasma by radioimmunoassay. It is shown that the sensitivity of the adrenals to a single injection of ACTH is independent of the phase of the menstrual cycle and the inhibitory effects of ACTH on progesterone secretion is exhibited only in the presence of an actively functioning corpus luteus of the ovary.

  10. ALG-2 knockdown in HeLa cells results in G2/M cell cycle phase accumulation and cell death

    DEFF Research Database (Denmark)

    Høj, Berit Rahbek; la Cour, Peter Jonas Marstrand; Mollerup, Jens

    2009-01-01

    downregulation induces accumulation of HeLa cells in the G2/M cell cycle phase and increases the amount of early apoptotic and dead cells. Caspase inhibition by the pan-caspase inhibitor zVAD-fmk attenuated the increase in the amount of dead cells following ALG-2 downregulation. Thus, our results indicate...... that ALG-2 has an anti-apoptotic function in HeLa cells by facilitating the passage through checkpoints in the G2/M cell cycle phase.......ALG-2 (apoptosis-linked gene-2 encoded protein) has been shown to be upregulated in a variety of human tumors questioning its previously assumed pro-apoptotic function. The aim of the present study was to obtain insights into the role of ALG-2 in human cancer cells. We show that ALG-2...

  11. Applications and control of air conditioning systems using rapid cycling to modulate capacity

    Energy Technology Data Exchange (ETDEWEB)

    Poort, M.J.; Bullard, C.W. [Department of Mechanical and Industrial Engineering, Air Conditioning and Refrigeration Center, University of Illinois, 1206 W. Green St., Urbana, IL 61801 (United States)

    2006-08-15

    Rapid cycling the compressor of an air conditioning or refrigeration system can be used to modulate capacity, thus offering an alternative to a variable speed compressor. This paper explores design tradeoffs to optimize rapid cycling performance based on experimental results using two different evaporators and changing other components of an air conditioning system. Rapid cycling has inherent compressor lift penalties associated with larger mass flow rates, which need to be minimized. Preventing dryout (superheating) in the evaporator during the off cycle, a major penalty as cycles are lengthened, is also important. Evaporator dryout is minimized by increasing the refrigerant side area and reducing off cycle drainage. Combining a flash gas bypass with a suction line heat exchanger was found to maximize performance during the off cycle while allowing increased cycle lengths without incurring major penalties. (author)

  12. Advanced and sustainable fuel cycles for innovative reactor systems

    International Nuclear Information System (INIS)

    Glatz, J. P.; Malmbeck, R.; Purroy, D. S.; Soucek, P.; Inoue, T.; Uozumi, K.

    2007-01-01

    The key objective of nuclear energy systems of the future as defined by the Generation IV road map is to provide a sustainable energy generation for the future. It includes the requirement to minimize the nuclear waste produced and thereby notably reduce the long term stewardship burden in the future. It is therefore evident that the corresponding fuel cycles will play a central role in trying to achieve these goals by creating clean waste streams which contain almost exclusively the fission products. A new concept based on a grouped separation of actinides is widely discussed in this context, but it is of course a real challenge to achieve this type of separation since technologies available today have been developed to separate actinides from each other. In France, the CEA has launched extensive research programs in the ATALANTE facility in Marcoule to develop the advanced fuel cycles for new generation reactor systems. In this so called global actinide management (GAM) concept, the actinides are extracted in a sequence of chemical reactions (grouped actinide extraction (GANEX)) and immediately reintroduced in the fuel fabrication process is to use all actinides in the energy production process. The new group separation processes can be derived as in this case from aqueous techniques but also from so-called pyrochemical partitioning processes. Significant progress was made in recent years for both routes in the frame of the European research projects PARTNEW, PYROREP and EUROPART, mainly devoted to the separation of minor actinides in the frame of partitioning and transmutation (P and T) studies. The fuels used in the new generation reactors will be significantly different from the commercial fuels of today. Because of the fuel type and the very high burn-ups reached, pyrometallurgical reprocessing could be the preferred method. The limited solubility of some of the fuel materials in acidic aqueous solutions, the possibility to have an integrated irradiation and

  13. Phase 1 study of metallic cask systems for spent fuel management from reactor to repository. Volume I. Phase 1 study summary

    International Nuclear Information System (INIS)

    1986-02-01

    It was proposed to perform a systems evaluation of metallic cask systems in order to define and examine the use of various metallic cask concepts or combination of concepts for the overall inventory management of spent fuel starting with its discharge from reactors to its emplacement in geologic repositories. This systems evaluation occurs in three phases. This three phase systems evaluation leads to a definition and recommendation of a sound and practical metallic cask system to accomplish efficient and effective management of spent fuel in the back end of the nuclear fuel cycle. Phase 1 Study objectives: establish system-wide functional criteria and assumptions; perform the systems engineering needed to define the metallic cask concepts and their feasibility; perform a screening evaluation of the technical and economic merits of the concepts; and recommend those to be included for a more detailed systems evaluation in Phase 2. Phase 2 Study objectives: refine the system-wide functional criteria and assumptions; perform the design engineering needed to enhance the validity and workability of those concepts recommended in Phase 1; and perform a more detailed systems evaluation. Phase 3 Study objectives: conclude the systems evaluation and develop an implementation plan. Volume I presents an overview of the detailed systems evaluation presented in Volume II

  14. Bioenergetic coupling between membrane transport systems and biosynthetic pathways essential for cell cycle progression

    International Nuclear Information System (INIS)

    Leister, K.J.; Cutry, A.F.; Wenner, C.E.

    1986-01-01

    Recently, it has been shown that there exists a point in the cell cycle (approximately 2 h prior to S phase entry) when (Na + /K + )ATPase pump activity is no longer needed for progression through the cycle. These data suggests that pump activity is critical in the biosynthetic processes which enables the cell to proceed through the G 1 phase. A scheme is proposed which is currently being tested that (Na + /K + )ATPase pump activity serves as the driving force in the regulation of other membrane transport processes critical for cell proliferation. For example, in post-confluent quiescent C3H-10T1/2 fibroblasts, when [K + ]/sub o/ is lowered just below the K/sub m/ of the pump for K + there is a 10-fold increase in 3 H-uridine uptake into both acid soluble and insoluble cell fractions. By modulation of the pump in this manner, glucose utilization is enhanced whereas inhibition of the pump by ouabain suppresses glucose utilization. In both methods of affecting the pump, 3 H-leucine incorporation is inhibited. Electron acceptors that influence the redox state of the cell have been shown to both stimulate or inhibit cell cycle progression. Under conditions where [K + ]/sub o/ is lowered, the nucleoside uptake responses observed were modified by electron acceptors depending on the ability to oxidize NAD(P)H directly or to interact with a cytochrome-like component, (e.g. phenazine methosulfate) reversed the enhanced uridine uptake and p-phenylene diamine further enhanced the uridine uptake response. These findings suggest that a plasma membrane redox system (presumably cyt-c like) is linked to nucleoside transport which is subject to (Na + /K + )ATPase activity

  15. Open cycle ocean thermal energy conversion system structure

    Science.gov (United States)

    Wittig, J. Michael

    1980-01-01

    A generally mushroom-shaped, open cycle OTEC system and distilled water producer which has a skirt-conduit structure extending from the enlarged portion of the mushroom to the ocean. The enlarged part of the mushroom houses a toroidal casing flash evaporator which produces steam which expands through a vertical rotor turbine, partially situated in the center of the blossom portion and partially situated in the mushroom's stem portion. Upon expansion through the turbine, the motive steam enters a shell and tube condenser annularly disposed about the rotor axis and axially situated beneath the turbine in the stem portion. Relatively warm ocean water is circulated up through the radially outer skirt-conduit structure entering the evaporator through a radially outer portion thereof, flashing a portion thereof into motive steam, and draining the unflashed portion from the evaporator through a radially inner skirt-conduit structure. Relatively cold cooling water enters the annular condenser through the radially inner edge and travels radially outwardly into a channel situated along the radially outer edge of the condenser. The channel is also included in the radially inner skirt-conduit structure. The cooling water is segregated from the potable, motive steam condensate which can be used for human consumption or other processes requiring high purity water. The expansion energy of the motive steam is partially converted into rotational mechanical energy of the turbine rotor when the steam is expanded through the shaft attached blades. Such mechanical energy drives a generator also included in the enlarged mushroom portion for producing electrical energy. Such power generation equipment arrangement provides a compact power system from which additional benefits may be obtained by fabricating the enclosing equipment, housings and component casings from low density materials, such as prestressed concrete, to permit those casings and housings to also function as a floating

  16. Effects of gamma radiation on phases of evolutional cycle of Corcyra cephalonica (Stainton, 1865) (Lepidoptera pyralidae) in artificial diet

    International Nuclear Information System (INIS)

    Aguilar, J.A.D.

    1991-04-01

    The effects of the increase in the gamma radiation ( 60 Co) doses on different phases of the evolutional cycle of Corcyra cephalonica (Stainton, 1865) (Lepidoptera Pyraliade) are studied. A cobalt 60 source type gamma beam 650 was used and the activity was of approximately 2.91 x 10 14 Bq. The experiments were conducted under controlled conditions with temperature at 25 ± 2 0 C and relative humidity of 70 ± 10%. (M.A.C.)

  17. Orbit Transfer Vehicle Engine Study. Phase A, extension 1: Advanced expander cycle engine optimization

    Science.gov (United States)

    Mellish, J. A.

    1979-01-01

    The performance optimization of expander cycle engines at vacuum thrust levels of 10K, 15K, and 20K lb is discussed. The optimization is conducted for a maximum engine length with an extendible nozzle in the retracted position of 60 inches and an engine mixture ratio of 6.0:1. The thrust chamber geometry and cycle analyses are documented. In addition, the sensitivity of a recommended baseline expander cycle to component performance variations is determined and chilldown/start propellant consumptions are estimated.

  18. Phase and amplitude control system for Stanford Linear Accelerator

    International Nuclear Information System (INIS)

    Yoo, S.J.

    1983-01-01

    The computer controlled phase and amplitude detection system measures the instantaneous phase and amplitude of a 1 micro-second 2856 MHz rf pulse at a 180 Hz rate. This will be used for phase feedback control, and also for phase and amplitude jitter measurement. The program, which was originally written by John Fox and Keith Jobe, has been modified to improve the function of the system. The software algorithms used in the measurement are described, as is the performance of the prototype phase and amplitude detector system

  19. Phase Multistability in Coupled Oscillator Systems

    DEFF Research Database (Denmark)

    Mosekilde, Erik; Postnov, D.E.; Sosnovtseva, Olga

    2003-01-01

    along the orbit of the individual oscillator. Focusing on the mechanisms underlying the appearance of phase multistability, the paper examines a variety of phase-locked patterns. In particular we demonstrate the nested structure of synchronization regions for oscillations with multicrest wave forms...

  20. The phase detection and calculation for low hybrid wave phase-feedback control system

    International Nuclear Information System (INIS)

    Liu Qiang; Liang Hao; Zhou Yongzhao; Shan Jiafang

    2008-01-01

    A method of phase detection and calculation for low hybrid wave phase-feedback control system and the implementing the algorithms on DSP cores embedded in FPGA is introduced. By taking the advantages of matlab-aided design and algorithms optimization to carry out parallel processing of multi-channel phase calculation in FPGA with rich resources, the purposed of fast phase-feedback control is achieved under the need of complicated mathematical operations. (authors)

  1. Women's preferences for sexual dimorphism in height depend on menstrual cycle phase and expected duration of relationship.

    Science.gov (United States)

    Pawlowski, Boguslaw; Jasienska, Grazyna

    2005-09-01

    Human mate preferences are related to many morphological traits, such as female waist-to-hip ratio (WHR), body mass index (BMI), male height or facial symmetry. People also vary in preferences for sexual dimorphism in stature (SDS = male height/female height) between themselves and a potential partner. Here, we demonstrate that women adjust their preference for SDS not only in relation to their own height but also in relation to (1) the phase of menstrual cycle during which their preferences were studied and (2) the sexual strategy (short- versus long-term) they were asked to choose. Taller males (larger SDS) were preferred more often when women were in the follicular (i.e. fertile) phase of their menstrual cycle and when the partners were chosen for short-term relationships. These effects were independent of woman's height. The results show that women in a potentially fertile phase of their menstrual cycle and when choosing a partner who might be less likely to invest in children select genes of taller males.

  2. Effects of menstrual cycle phase on ratings of implicitly erotic art.

    Science.gov (United States)

    Rudski, Jeffrey M; Bernstein, Lauren R; Mitchell, Joy E

    2011-08-01

    Women's perceptions of and responses to explicitly erotic stimuli have been shown to vary across the menstrual cycle. The present study examined responses to implicit eroticism. A total of 83 women provided reactions to paintings by Georgia O'Keeffe in 6 day intervals over the course of 1 month. Among freely cycling women (n = 37), 31% of their descriptions included sexual themes during the first half of their cycle, dropping to 9% of descriptions in the second half. In women using oral contraceptives (n = 46), there was no significant difference in descriptions across the cycle (13% in the first half vs. 17% in the second half). Results were discussed in terms of evolutionary psychology and social-cognitive perspectives on the relationships between hormonal fluctuations and sexuality.

  3. Tracheal sound parameters of respiratory cycle phases show differences between flow-limited and normal breathing during sleep

    International Nuclear Information System (INIS)

    Kulkas, A; Huupponen, E; Virkkala, J; Saastamoinen, A; Rauhala, E; Tenhunen, M; Himanen, S-L

    2010-01-01

    The objective of the present work was to develop new computational parameters to examine the characteristics of respiratory cycle phases from the tracheal breathing sound signal during sleep. Tracheal sound data from 14 patients (10 males and 4 females) were examined. From each patient, a 10 min long section of normal and a 10 min section of flow-limited breathing during sleep were analysed. The computationally determined proportional durations of the respiratory phases were first investigated. Moreover, the phase durations and breathing sound amplitude levels were used to calculate the area under the breathing sound envelope signal during inspiration and expiration phases. An inspiratory sound index was then developed to provide the percentage of this type of area during the inspiratory phase with respect to the combined area of inspiratory and expiratory phases. The proportional duration of the inspiratory phase showed statistically significantly higher values during flow-limited breathing than during normal breathing and inspiratory pause displayed an opposite difference. The inspiratory sound index showed statistically significantly higher values during flow-limited breathing than during normal breathing. The presented novel computational parameters could contribute to the examination of sleep-disordered breathing or as a screening tool

  4. System identification on two-phase flow stability

    International Nuclear Information System (INIS)

    Wu Shaorong; Zhang Youjie; Wang Dazhong; Bo Jinghai; Wang Fei

    1996-01-01

    The theoretical principle, experimental method and results of interrelation analysis identification for the instability of two-phase flow are described. A completely new concept of test technology and method on two-phase flow stability was developed by using he theory of information science on system stability and system identification for two-phase flow stability in thermo-physics field. Application of this method would make it possible to identify instability boundary of two-phase flow under stable operation conditions of two-phase flow system. The experiment was carried out on the thermohydraulic test system HRTL-5. Using reverse repeated pseudo-random sequences of heating power as input signal sources and flow rate as response function in the test, the two-phase flow stability and stability margin of the natural circulation system are investigated. The effectiveness and feasibility of identifying two-phase flow stability by using this system identification method were experimentally demonstrated. Basic data required for mathematics modeling of two-phase flow and analysis of two-phase flow stability were obtained, which are useful for analyzing, monitoring of the system operation condition, and forecasting of two-phase flow stability in engineering system

  5. Enterprise and system of systems capability development life-cycle processes.

    Energy Technology Data Exchange (ETDEWEB)

    Beck, David Franklin [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2014-08-01

    This report and set of appendices are a collection of memoranda originally drafted circa 2007-2009 for the purpose of describing and detailing a models-based systems engineering approach for satisfying enterprise and system-of-systems life cycle process requirements. At the time there was interest and support to move from Capability Maturity Model Integration (CMMI) Level One (ad hoc processes) to Level Three. The main thrust of the material presents a rational exposâe of a structured enterprise development life cycle that uses the scientific method as a framework, with further rigor added from adapting relevant portions of standard systems engineering processes. While the approach described invokes application of the Department of Defense Architectural Framework (DoDAF), it is suitable for use with other architectural description frameworks.

  6. Induction accelerators for the phase rotator system

    International Nuclear Information System (INIS)

    Reginato, Lou; Yu, Simon; Vanecek, Dave

    2001-01-01

    The principle of magnetic induction has been applied to the acceleration of high current beams in betatrons and a variety of induction accelerators. The linear induction accelerator (LIA) consists of a simple nonresonant structure where the drive voltage is applied to an axially symmetric gap that encloses a toroidal ferromagnetic material. The change in flux in the magnetic core induces an axial electric field that provides particle acceleration. This simple nonresonant (low Q) structure acts as a single turn transformer that can accelerate from hundreds of amperes to tens of kiloamperes, basically only limited by the drive impedance. The LIA is typically a low gradient structure that can provide acceleration fields of varying shapes and time durations from tens of nanoseconds to several microseconds. The efficiency of the LIA depends on the beam current and can exceed 50% if the beam current exceeds the magnetization current required by the ferromagnetic material. The acceleration voltage available is simply given by the expression V=A dB/dt. Hence, for a given cross section of material, the beam pulse duration influences the energy gain. Furthermore, a premium is put on minimizing the diameter, which impacts the total weight or cost of the magnetic material. The diameter doubly impacts the cost of the LIA since the power (cost) to drive the cores is proportional to the volume as well. The waveform requirements during the beam pulse makes it necessary to make provisions in the pulsing system to maintain the desired dB/dt during the useful part of the acceleration cycle. This is typically done two ways, by using the final stage of the pulse forming network (PFN) and by the pulse compensation network usually in close proximity of the acceleration cell. The choice of magnetic materials will be made by testing various materials both ferromagnetic and ferrimagnetic. These materials will include the nickel-iron, silicon steel amorphous and various types of ferrites not

  7. Combinatorial evaluation of systems including decomposition of a system representation into fundamental cycles

    Science.gov (United States)

    Oliveira, Joseph S [Richland, WA; Jones-Oliveira, Janet B [Richland, WA; Bailey, Colin G [Wellington, NZ; Gull, Dean W [Seattle, WA

    2008-07-01

    One embodiment of the present invention includes a computer operable to represent a physical system with a graphical data structure corresponding to a matroid. The graphical data structure corresponds to a number of vertices and a number of edges that each correspond to two of the vertices. The computer is further operable to define a closed pathway arrangement with the graphical data structure and identify each different one of a number of fundamental cycles by evaluating a different respective one of the edges with a spanning tree representation. The fundamental cycles each include three or more of the vertices.

  8. Nondegenerate parametric generation of 2.2-mJ, few-cycle 2.05-μm pulses using a mixed phase matching scheme

    International Nuclear Information System (INIS)

    Xu, Guibao; Wandel, Scott F.; Jovanovic, Igor

    2014-01-01

    We describe the production of 2.2-mJ, ∼6 optical-cycle-long mid-infrared laser pulses with a carrier wavelength of 2.05 μm in a two-stage β-BaB 2 O 4 nondegenerate optical parametric amplifier design with a mixed phase matching scheme, which is pumped by a standard Ti:sapphire chirped-pulse amplification system. It is demonstrated that relatively high pulse energies, short pulse durations, high stability, and excellent beam profiles can be obtained using this simple approach, even without the use of optical parametric chirped-pulse amplification

  9. A phase one AR/C system design

    Science.gov (United States)

    Kachmar, Peter M.; Polutchko, Robert J.; Matusky, Martin; Chu, William; Jackson, William; Montez, Moises

    1991-01-01

    The Phase One AR&C System Design integrates an evolutionary design based on the legacy of previous mission successes, flight tested components from manned Rendezvous and Proximity Operations (RPO) space programs, and additional AR&C components validated using proven methods. The Phase One