WorldWideScience

Sample records for current scientific literature

  1. Pharmacological and analytical aspects of withaferin A:A concise report of current scientific literature

    Institute of Scientific and Technical Information of China (English)

    Kanika Patel; Ravi B Singh; Dinesh K Patel

    2013-01-01

    Withaferin A is an important phytoconstituents of Withania somnifera (W. Somnifera) belonging to the category of withanolides, that are a group of naturally occurring C28-steroidal lactone triterpenoids. Withaferin A has been used in the traditional and indigenous system of medicine for the treatment of various disorders. In view of its unique therapeutic potential, it has gained much attention in the modern science. In the couple of the years, Withaferin A has been scientifically validated for different pharmacological activities including anti-cancer, adaptogenic, anti-stress, anti-convulsant, immunomodulatory, neurological, anti-inflammatory, anti-tumor, cardioprotective, and neuroprotective activities. Pharmacological and analytical aspects of Withaferin A were highlighted in the present article. From the literature review it was found that Withaferin A has a very impressive pharmacological profile especially against cancer and could be useful for the development of the new drug in the future for the treatment of cancer and other metabolic disorders.

  2. Medicinal significance, pharmacological activities, and analytical aspects of solasodine: A concise report of current scientific literature

    Directory of Open Access Journals (Sweden)

    Kanika Patel

    2013-01-01

    Full Text Available Alkaloids are well known phytoconstituents for their diverse pharmacological properties. Alkaloids are found in all plant parts like roots, stems, leaves, flowers, fruits and seeds. Solasodine occurs as an aglycone part of glycoalkloids, which is a nitrogen analogue to sapogenins. Solanaceae family comprises of a number of plants with variety of natural products of medicinal significance mainly steroidal lactones, glycosides, alkaloids and flavanoids. It is a steroidal alkaloid based on a C27 cholestane skeleton. Literature survey reveals that solasodine has diuretic, anticancer, antifungal, cardiotonic, antispermatogenetic, antiandrogenic, immunomodulatory, antipyretic and various effects on central nervous system. Isolation and quantitative determination was achieved by several analytical techniques. Present review highlights the pharmacological activity of solasodine, with its analytical and tissue culture techniques, which may be helpful to the researchers to develop new molecules for the treatment of various disorders in the future.

  3. Pharmacologically screened aphrodisiac plant-A review of current scientific literature

    Institute of Scientific and Technical Information of China (English)

    Patel DK; Kumar R; Prasad SK; Hemalatha S

    2011-01-01

    Substances which are used to treat sexual dysfunction or to improve sexual behavior and satisfaction in humans and animals are called ‘aphrodisiac’. Uses of plant material to treat sexual disorder is a long back history in the different system of medicine and it was practiced by different type of vaidyas and traditional healer in almost all the countries in the world, like China, India, Egypt, Rome and Greek. Even though there was an unavailability of the scientific data, these substances have been used as aphrodisiac. During the historic times Lytta vesicatoria,Tribulus terrestris, Ptychopetalum olacoides, Crocus sativus, Bufo marinus, Myristica fragrans, Theobroma cocao and other plants have been investigated for its aphrodisiac activity by in vivo and in vitro model. Even though the study showed positive response to a particular substance, there is always a need to run the clinical trial before administering the tested drug in human being. The present review article summarizes the plant material which has been tested for its aphrodisiac activity in different experimental model (in vitro, in vivo on animal models, or in human clinical trials) and comply its claim in the different system of medicine. A brief overview about the data of percentage study in the last eighteen years duration on aphrodisiac activity of plant material was done on the basis of the CAB abstract database.

  4. Scientific Imagination in Literature.

    Science.gov (United States)

    Stableford, Brian M.

    1978-01-01

    Discusses the conflict between the religious and scientific imaginations as existing between the intellectual realms of unquestioning faith and constant questioning. Relates this conflict to writers of the seventeenth and eighteenth centuries, e.g., Bacon, Kepler, Wilkins, Godwin, Harrington, Campanella, Cyrano, Le Bret, Defoe, Swift, Voltiare,…

  5. Geant4 in Scientific Literature

    CERN Document Server

    Pia, M G; Bell, Z W; Dressendorfer, P V

    2009-01-01

    The Geant4 reference paper published in Nuclear Instruments and Methods A in 2003 has become the most cited publication in the whole Nuclear Science and Technology category of Thomson-Reuter's Journal Citation Reports. It is currently the second most cited article among the publications authored by two major research institutes, CERN and INFN. An overview of Geant4 presence (and absence) in scholarly literature is presented; the patterns of Geant4 citations are quantitatively examined and discussed.

  6. Access to the scientific literature

    Science.gov (United States)

    Albarède, Francis

    The Public Library of Science Open Letter (http://www.publiclibraryofscience.org) is a very generous initiative, but, as most similar initiatives since the advent of electronic publishing, it misses the critical aspects of electronic publishing.Ten years ago, a Publisher would be in charge of running a system called a “scientific journal.” In such a system, the presence of an Editor and peer Reviewers secures the strength of the science and the rigor of writing; the Publisher guarantees the professional quality of printing, efficient dissemination, and long-term archiving. Publishing used to be in everyone's best interest, or nearly everyone. The Publisher, because he/she is financially motivated, ensures widespread dissemination of the journal amongst libraries and individual subscribers. The interest of the Author is that the system guarantees a broad potential readership. The interest of the Reader is that a line is drawn between professionally edited literature, presumably of better quality, and gray literature or home publishing, so that he/she does not waste time going through ‘low yield’ ungraded information. The Publisher could either be a private company, an academic institution, or a scholarly society. My experience is that, when page charges and subscription rates are compounded, journals published by scholarly societies are not necessarily cheaper. The difference between these cases is not the cost of running an office with rents, wages, printing, postage, advertisement, and archiving, but that a private Publisher pays shareholders. Shareholders have the bad habit of minding their own business and, therefore, they may interfere negatively with scientific publishing. Nevertheless, while the stranglehold imposed by private Publishers on our libraries over the last 10 years by increasing subscription rates may in part be due to shareholders' greed, this is true only in part. The increases are also a consequence of the booming number of pages being

  7. Bibliography: Current world literature.

    Science.gov (United States)

    2009-07-01

    This bibliography is compiled by clinicians from the journals listed at the end of this publication. It is based on literature entered into our database between 1 March 2008 and 28 February 2009 (articles are generally added to the database about two and a half months after publication). In addition, the bibliography contains every paper annotated by reviewers; these references were obtained from a variety of bibliographic databases and published between the beginning of the review period and the time of going to press. The bibliography has been grouped into topics that relate to the reviews in this issue.

  8. Bibliography. Current world literature.

    Science.gov (United States)

    2009-07-01

    This bibliography is compiled by clinicians from the journals listed at the end of this publication. It is based on literature entered into our database between 1 March 2008 and 28 February 2009 (articles are generally added to the database about two and a half months after publication). In addition, the bibliography contains every paper annotated by reviewers; these references were obtained from a variety of bibliographic databases and published between the beginning of the review period and the time of going to press. The bibliography has been grouped into topics that relate to the reviews in this issue.

  9. Testing Scientific Software: A Systematic Literature Review.

    Science.gov (United States)

    Kanewala, Upulee; Bieman, James M

    2014-10-01

    Scientific software plays an important role in critical decision making, for example making weather predictions based on climate models, and computation of evidence for research publications. Recently, scientists have had to retract publications due to errors caused by software faults. Systematic testing can identify such faults in code. This study aims to identify specific challenges, proposed solutions, and unsolved problems faced when testing scientific software. We conducted a systematic literature survey to identify and analyze relevant literature. We identified 62 studies that provided relevant information about testing scientific software. We found that challenges faced when testing scientific software fall into two main categories: (1) testing challenges that occur due to characteristics of scientific software such as oracle problems and (2) testing challenges that occur due to cultural differences between scientists and the software engineering community such as viewing the code and the model that it implements as inseparable entities. In addition, we identified methods to potentially overcome these challenges and their limitations. Finally we describe unsolved challenges and how software engineering researchers and practitioners can help to overcome them. Scientific software presents special challenges for testing. Specifically, cultural differences between scientist developers and software engineers, along with the characteristics of the scientific software make testing more difficult. Existing techniques such as code clone detection can help to improve the testing process. Software engineers should consider special challenges posed by scientific software such as oracle problems when developing testing techniques.

  10. Sources of error in the retracted scientific literature

    Science.gov (United States)

    Casadevall, Arturo; Steen, R. Grant; Fang, Ferric C.

    2014-01-01

    Retraction of flawed articles is an important mechanism for correction of the scientific literature. We recently reported that the majority of retractions are associated with scientific misconduct. In the current study, we focused on the subset of retractions for which no misconduct was identified, in order to identify the major causes of error. Analysis of the retraction notices for 423 articles indexed in PubMed revealed that the most common causes of error-related retraction are laboratory errors, analytical errors, and irreproducible results. The most common laboratory errors are contamination and problems relating to molecular biology procedures (e.g., sequencing, cloning). Retractions due to contamination were more common in the past, whereas analytical errors are now increasing in frequency. A number of publications that have not been retracted despite being shown to contain significant errors suggest that barriers to retraction may impede correction of the literature. In particular, few cases of retraction due to cell line contamination were found despite recognition that this problem has affected numerous publications. An understanding of the errors leading to retraction can guide practices to improve laboratory research and the integrity of the scientific literature. Perhaps most important, our analysis has identified major problems in the mechanisms used to rectify the scientific literature and suggests a need for action by the scientific community to adopt protocols that ensure the integrity of the publication process.—Casadevall, A., Steen, R. G., Fang, F. C. Sources of error in the retracted scientific literature. PMID:24928194

  11. Recognizing scientific artifacts in biomedical literature.

    Science.gov (United States)

    Groza, Tudor; Hassanzadeh, Hamed; Hunter, Jane

    2013-01-01

    Today's search engines and digital libraries offer little or no support for discovering those scientific artifacts (hypotheses, supporting/contradicting statements, or findings) that form the core of scientific written communication. Consequently, we currently have no means of identifying central themes within a domain or to detect gaps between accepted knowledge and newly emerging knowledge as a means for tracking the evolution of hypotheses from incipient phases to maturity or decline. We present a hybrid Machine Learning approach using an ensemble of four classifiers, for recognizing scientific artifacts (ie, hypotheses, background, motivation, objectives, and findings) within biomedical research publications, as a precursory step to the general goal of automatically creating argumentative discourse networks that span across multiple publications. The performance achieved by the classifiers ranges from 15.30% to 78.39%, subject to the target class. The set of features used for classification has led to promising results. Furthermore, their use strictly in a local, publication scope, ie, without aggregating corpus-wide statistics, increases the versatility of the ensemble of classifiers and enables its direct applicability without the necessity of re-training.

  12. Harnessing Scientific Literature Reports for Pharmacovigilance

    Science.gov (United States)

    Ripple, Anna; Tonning, Joseph; Munoz, Monica; Hasan, Rashedul; Ly, Thomas; Francis, Henry; Bodenreider, Olivier

    2017-01-01

    Summary Objectives We seek to develop a prototype software analytical tool to augment FDA regulatory reviewers’ capacity to harness scientific literature reports in PubMed/MEDLINE for pharmacovigilance and adverse drug event (ADE) safety signal detection. We also aim to gather feedback through usability testing to assess design, performance, and user satisfaction with the tool. Methods A prototype, open source, web-based, software analytical tool generated statistical disproportionality data mining signal scores and dynamic visual analytics for ADE safety signal detection and management. We leveraged Medical Subject Heading (MeSH) indexing terms assigned to published citations in PubMed/MEDLINE to generate candidate drug-adverse event pairs for quantitative data mining. Six FDA regulatory reviewers participated in usability testing by employing the tool as part of their ongoing real-life pharmacovigilance activities to provide subjective feedback on its practical impact, added value, and fitness for use. Results All usability test participants cited the tool’s ease of learning, ease of use, and generation of quantitative ADE safety signals, some of which corresponded to known established adverse drug reactions. Potential concerns included the comparability of the tool’s automated literature search relative to a manual ‘all fields’ PubMed search, missing drugs and adverse event terms, interpretation of signal scores, and integration with existing computer-based analytical tools. Conclusions Usability testing demonstrated that this novel tool can automate the detection of ADE safety signals from published literature reports. Various mitigation strategies are described to foster improvements in design, productivity, and end user satisfaction. PMID:28326432

  13. Communication about scientific uncertainty in environmental nanoparticle research - a comparison of scientific literature and mass media

    Science.gov (United States)

    Heidmann, Ilona; Milde, Jutta

    2014-05-01

    The research about the fate and behavior of engineered nanoparticles in the environment is despite its wide applications still in the early stages. 'There is a high level of scientific uncertainty in nanoparticle research' is often stated in the scientific community. Knowledge about these uncertainties might be of interest to other scientists, experts and laymen. But how could these uncertainties be characterized and are they communicated within the scientific literature and the mass media? To answer these questions, the current state of scientific knowledge about scientific uncertainty through the example of environmental nanoparticle research was characterized and the communication of these uncertainties within the scientific literature is compared with its media coverage in the field of nanotechnologies. The scientific uncertainty within the field of environmental fate of nanoparticles is by method uncertainties and a general lack of data concerning the fate and effects of nanoparticles and their mechanisms in the environment, and by the uncertain transferability of results to the environmental system. In the scientific literature, scientific uncertainties, their sources, and consequences are mentioned with different foci and to a different extent. As expected, the authors in research papers focus on the certainty of specific results within their specific research question, whereas in review papers, the uncertainties due to a general lack of data are emphasized and the sources and consequences are discussed in a broader environmental context. In the mass media, nanotechnology is often framed as rather certain and positive aspects and benefits are emphasized. Although reporting about a new technology, only in one-third of the reports scientific uncertainties are mentioned. Scientific uncertainties are most often mentioned together with risk and they arise primarily from unknown harmful effects to human health. Environmental issues itself are seldom mentioned

  14. Nobel Prize winners for literature as palliative for scientific English.

    Science.gov (United States)

    Sri Kantha, Sachi

    2003-02-01

    Plagiarism causes a serious concern in scientific literature. I distinguish two types of plagiarism. What is routinely highlighted and discussed is the reprehensible type of stealing another author's ideas and words. This type I categorize as "heterotrophic" plagiarism. A more prevalent and less-discussed type of plagiarism is the verbatim use of same sentences repetitively by authors in their publications. This I categorize as "autotrophic" plagiarism. Though harmless per se, autotrophic plagiarism is equally taxing on the readers. The occurrence of autotrophic plagiarism is mainly caused by the lack of proficiency in the current lingua franca of science, ie, English. The writings of 22 Nobel literature laureates who wrote in English, especially their travelogues, essays, and letters to the press can be used for benefit of improving one's own vocabulary and writing skills and style. I suggest the writings of three literati--Bernard Shaw, Bertrand Russell, and Ernest Hemingway--as palliatives for autotrophic plagiarism in scientific publishing.

  15. Extraction of transcript diversity from scientific literature.

    Directory of Open Access Journals (Sweden)

    Parantu K Shah

    2005-06-01

    Full Text Available Transcript diversity generated by alternative splicing and associated mechanisms contributes heavily to the functional complexity of biological systems. The numerous examples of the mechanisms and functional implications of these events are scattered throughout the scientific literature. Thus, it is crucial to have a tool that can automatically extract the relevant facts and collect them in a knowledge base that can aid the interpretation of data from high-throughput methods. We have developed and applied a composite text-mining method for extracting information on transcript diversity from the entire MEDLINE database in order to create a database of genes with alternative transcripts. It contains information on tissue specificity, number of isoforms, causative mechanisms, functional implications, and experimental methods used for detection. We have mined this resource to identify 959 instances of tissue-specific splicing. Our results in combination with those from EST-based methods suggest that alternative splicing is the preferred mechanism for generating transcript diversity in the nervous system. We provide new annotations for 1,860 genes with the potential for generating transcript diversity. We assign the MeSH term "alternative splicing" to 1,536 additional abstracts in the MEDLINE database and suggest new MeSH terms for other events. We have successfully extracted information about transcript diversity and semiautomatically generated a database, LSAT, that can provide a quantitative understanding of the mechanisms behind tissue-specific gene expression. LSAT (Literature Support for Alternative Transcripts is publicly available at http://www.bork.embl.de/LSAT/.

  16. Nanotoxicology: characterizing the scientific literature, 2000-2007

    Energy Technology Data Exchange (ETDEWEB)

    Ostrowski, Alexis D.; Martin, Tyronne; Conti, Joseph; Hurt, Indy; Harthorn, Barbara Herr, E-mail: harthorn@cns.ucsb.ed [University of California, NSF Center for Nanotechnology in Society (United States)

    2009-02-15

    Understanding the toxicity of nanomaterials and nano-enabled products is important for human and environmental health and safety as well as public acceptance. Assessing the state of knowledge about nanotoxicology is an important step in promoting comprehensive understanding of the health and environmental implications of these new materials. To this end, we employed bibliometric techniques to characterize the prevalence and distribution of the current scientific literature. We found that the nano-toxicological literature is dispersed across a range of disciplines and sub-fields; focused on in vitro testing; often does not specify an exposure pathway; and tends to emphasize acute toxicity and mortality rather than chronic exposure and morbidity. Finally, there is very little research on consumer products, particularly on their environmental fate, and most research is on the toxicity of basic nanomaterials. The implications for toxicologists, regulators and social scientists studying nanotechnology and society are discussed.

  17. The contamination of scientific literature: looking for an antidote

    Science.gov (United States)

    Liotta, Marcello

    2017-04-01

    Science may have very strong implications for society. The knowledge of the processes occurring around the society represents a good opportunity to take responsible decisions. This is particularly true in the field of geosciences. Earthquakes, volcanic eruptions, landslides, climate changes and many other natural phenomena still need to be further investigated. The role of the scientific community is to increase the knowledge. Each member can share his own ideas and data thus allowing the entire scientific community to receive a precious contribution. The latter one often derives from research activities, which are expensive in terms of consumed time and resources. Nowadays the sharing of scientific results occurs through the publication on scientific journals. The reading of available scientific literature thus represents a unique opportunity to define the state of the art on a specific topic and to address research activities towards something new. When published results are obtained through a rigorous scientific process, they constitute a solid background where each member can add his ideas and evidences. Differently, published results may be affected by scientific misconduct; they constitute a labyrinth where the scientists lose their time in the attempt of truly understanding the natural processes. The normal scientific dialectic should unmask such results, thus avoiding literature contamination and making the scientific framework more stimulating. The scientific community should look for the best practice to reduce the risk of literature contamination.

  18. Scientific Literature as Hierarchy: Library Instruction and Robert M. Gagne.

    Science.gov (United States)

    Miller, Constance R.

    1982-01-01

    Establishes the connection between the learning theories of Robert M. Gagne and systematic patterns in scientific literature and discusses implications of this connection for instruction in library use. Twenty-four references are listed. (Author/EJS)

  19. Scientific Literature as Hierarchy: Library Instruction and Robert M. Gagne.

    Science.gov (United States)

    Miller, Constance R.

    1982-01-01

    Establishes the connection between the learning theories of Robert M. Gagne and systematic patterns in scientific literature and discusses implications of this connection for instruction in library use. Twenty-four references are listed. (Author/EJS)

  20. Mining skeletal phenotype descriptions from scientific literature.

    Directory of Open Access Journals (Sweden)

    Tudor Groza

    Full Text Available Phenotype descriptions are important for our understanding of genetics, as they enable the computation and analysis of a varied range of issues related to the genetic and developmental bases of correlated characters. The literature contains a wealth of such phenotype descriptions, usually reported as free-text entries, similar to typical clinical summaries. In this paper, we focus on creating and making available an annotated corpus of skeletal phenotype descriptions. In addition, we present and evaluate a hybrid Machine Learning approach for mining phenotype descriptions from free text. Our hybrid approach uses an ensemble of four classifiers and experiments with several aggregation techniques. The best scoring technique achieves an F-1 score of 71.52%, which is close to the state-of-the-art in other domains, where training data exists in abundance. Finally, we discuss the influence of the features chosen for the model on the overall performance of the method.

  1. The scientific building blocks for business coaching: A literature review

    Directory of Open Access Journals (Sweden)

    Flip Schutte

    2015-03-01

    Full Text Available Orientation: Business coaching is a relatively new approach to leadership development. It is also slowly growing as an academic discipline with only a small number of active researchers and a dearth of published literature reviews.Research purpose: This article is an investigation into the current level of development of the body of knowledge related to business coaching by means of a systematic literature review.Motivation of the study: Previous literature reviews summarised the available published articles. In order to contribute to establishing business coaching as an independent academic discipline, the building blocks for science in the phenomenon under investigation have to be scientifically not only summarised, but also synthesised and explored to ground this new discipline as an academic field of research.Research design, approach and method: A methodological framework has been developed to analyse the information. The data were synthesised according to the following building blocks for science: concepts, definitions, typologies, models, theories and paradigms.Main findings: A total of 84 articles were accessed by the specified search strategy and 36 were analysed according to inclusive and exclusive criteria. Although coaching has not been sufficiently developed as an academic discipline, it is possible to develop a comprehensive definition of coaching, as well as to identify the main models and theories that apply to this field.Practical/managerial implications: This literature review has synthesised and summarised the available data in such a way that it will contribute to the conceptualisation and foundation of business coaching as an academic discipline.Contribution: The building blocks for business coaching as a relatively new and emerging science within the field of business leadership have been defined. This will contribute to the articulation of concepts within this discipline by future researchers and practitioners.

  2. Incorporating Primary Scientific Literature in Middle and High School Education

    Directory of Open Access Journals (Sweden)

    Sarah C. Fankhauser

    2015-11-01

    Full Text Available Primary literature is the most reliable and direct source of scientific information, but most middle school and high school science is taught using secondary and tertiary sources. One reason for this is that primary science articles can be difficult to access and interpret for young students and for their teachers, who may lack exposure to this type of writing. The Journal of Emerging Investigators (JEI was created to fill this gap and provide primary research articles that can be accessed and read by students and their teachers. JEI is a non-profit, online, open-access, peer-reviewed science journal dedicated to mentoring and publishing the scientific research of middle and high school students. JEI articles provide reliable scientific information that is written by students and therefore at a level that their peers can understand. For student-authors who publish in JEI, the review process and the interaction with scientists provide invaluable insight into the scientific process. Moreover, the resulting repository of free, student-written articles allows teachers to incorporate age-appropriate primary literature into the middle and high school science classroom. JEI articles can be used for teaching specific scientific content or for teaching the process of the scientific method itself. The critical thinking skills that students learn by engaging with the primary literature will be invaluable for the development of a scientifically-literate public.

  3. Incorporating Primary Scientific Literature in Middle and High School Education.

    Science.gov (United States)

    Fankhauser, Sarah C; Lijek, Rebeccah S

    2016-03-01

    Primary literature is the most reliable and direct source of scientific information, but most middle school and high school science is taught using secondary and tertiary sources. One reason for this is that primary science articles can be difficult to access and interpret for young students and for their teachers, who may lack exposure to this type of writing. The Journal of Emerging Investigators (JEI) was created to fill this gap and provide primary research articles that can be accessed and read by students and their teachers. JEI is a non-profit, online, open-access, peer-reviewed science journal dedicated to mentoring and publishing the scientific research of middle and high school students. JEI articles provide reliable scientific information that is written by students and therefore at a level that their peers can understand. For student-authors who publish in JEI, the review process and the interaction with scientists provide invaluable insight into the scientific process. Moreover, the resulting repository of free, student-written articles allows teachers to incorporate age-appropriate primary literature into the middle and high school science classroom. JEI articles can be used for teaching specific scientific content or for teaching the process of the scientific method itself. The critical thinking skills that students learn by engaging with the primary literature will be invaluable for the development of a scientifically-literate public.

  4. PFOA and possible health effects : A review of scientific literature

    NARCIS (Netherlands)

    Rijs KJ; Bogers RP; M&G; M&V

    2017-01-01

    Associations were found between blood concentrations of PFOA in humans and possible health effects and functioning of the body. This is the result of a review of previously performed reviews of the scientific literature on studies conducted among humans by the National Institute for Public Health

  5. Acquisition of Scientific Literature in Developing Countries. 2: Malaysia.

    Science.gov (United States)

    Taib, Rosna

    1989-01-01

    Describes the acquisition of scientific literature by academic libraries in Malaysia. The discussion covers the impact of government policies, library acquisition policies, the selection process, acquisition of special materials, the role of gifts and exchanges, and problems with customs clearance and censorship. Progress in cooperative…

  6. A retrospective of the GREGOR solar telescope in scientific literature

    CERN Document Server

    Denker, C; Feller, A; Arlt, K; Balthasar, H; Bauer, S -M; González, N Bello; Berkefeld, T; Caligari, P; Collados, M; Fischer, A; Granzer, T; Hahn, T; Halbgewachs, C; Heidecke, F; Hofmann, A; Kentischer, T; Klvaňa, M; Kneer, F; Lagg, A; Nicklas, H; Popow, E; Puschmann, K G; Rendtel, J; Schmidt, D; Schmidt, W; Sobotka, M; Solanki, S K; Soltau, D; Staude, J; Strassmeier, K G; Volkmer, R; Waldmann, T; Wiehr, E; Wittmann, A D; Woche, M

    2012-01-01

    In this review, we look back upon the literature, which had the GREGOR solar telescope project as its subject including science cases, telescope subsystems, and post-focus instruments. The articles date back to the year 2000, when the initial concepts for a new solar telescope on Tenerife were first presented at scientific meetings. This comprehensive bibliography contains literature until the year 2012, i.e., the final stages of commissioning and science verification. Taking stock of the various publications in peer-reviewed journals and conference proceedings also provides the "historical" context for the reference articles in this special issue of Astronomische Nachrichten/Astronomical Notes.

  7. The visibility of scientific misconduct: A review of the literature on retracted journal articles.

    Science.gov (United States)

    Hesselmann, Felicitas; Graf, Verena; Schmidt, Marion; Reinhart, Martin

    2017-10-01

    Retractions of scientific articles are becoming the most relevant institution for making sense of scientific misconduct. An increasing number of retracted articles, mainly attributed to misconduct, is currently providing a new empirical basis for research about scientific misconduct. This article reviews the relevant research literature from an interdisciplinary context. Furthermore, the results from these studies are contextualized sociologically by asking how scientific misconduct is made visible through retractions. This study treats retractions as an emerging institution that renders scientific misconduct visible, thus, following up on the sociology of deviance and its focus on visibility. The article shows that retractions, by highlighting individual cases of misconduct and general policies for preventing misconduct while obscuring the actors and processes through which retractions are effected, produce highly fragmented patterns of visibility. These patterns resemble the bifurcation in current justice systems.

  8. Human and the animal in Victorian gothic scientific literature

    OpenAIRE

    McKechnie, Claire Charlotte

    2011-01-01

    This doctoral thesis examines the role of animals in nineteenth-century science and Victorian Gothic fiction of the latter half of the century. It is interdisciplinary in its exploration of the interrelationship between science writings and literary prose and it seeks to place the Gothic animal body in its cultural and historical setting. This study is interested in the ways in which Gothic literature tests the limits of the human by using scientific ideas about disease, evolution, species co...

  9. Viziometrics: Analyzing Visual Information in the Scientific Literature

    OpenAIRE

    Lee, Po-shen; West, Jevin D.; Howe, Bill

    2016-01-01

    Scientific results are communicated visually in the literature through diagrams, visualizations, and photographs. These information-dense objects have been largely ignored in bibliometrics and scientometrics studies when compared to citations and text. In this paper, we use techniques from computer vision and machine learning to classify more than 8 million figures from PubMed into 5 figure types and study the resulting patterns of visual information as they relate to impact. We find that the...

  10. Training students to appraise the quality of scientific literature.

    Science.gov (United States)

    Arlt, Sebastian P; Heuwieser, Wolfgang

    2011-01-01

    Implementing evidence-based veterinary medicine (EBVM) into clinical practice requires not only the ability to retrieve, interpret, and apply the results of published scientific studies, but also the ability to critically evaluate the quality of the literature. These skills, however, are not widely taught in the veterinary curriculum. The objective of this study was to test a literature evaluation form (LEF) designed to assist veterinary students in appraising the quality of literature on animal reproduction and to compare their ability to do so with that of students who were provided with a control form (CF). The 68 participants were in their fifth year of study and attended a clinical rotation at the Clinic for Animal Reproduction. Students in the LEF group determined the quality of two scientific papers, considering statements about study design, information content, and objectivity, and determined rating points to obtain an overall score. Participants using the CF ranked the quality of the article without the assistance of the quality assessment form. The LEF group was able to more correctly assess the quality of the literature and the variability of the chosen evidence levels was higher in the CF group. The questionnaire was found to be a useful tool for the systematic assessment of the quality of publications within a reasonable period of time. Seventy-eight per cent of the participants agreed that the LEF helps them evaluate the quality and validity of biomedical scientific information. We conclude that courses that introduce EBVM should be taught in the first semesters of the veterinary curriculum so that students can develop competence in defining a clinical problem, retrieving information from the literature, and developing independent critical thinking.

  11. Open access to the scientific journal literature: situation 2009.

    Science.gov (United States)

    Björk, Bo-Christer; Welling, Patrik; Laakso, Mikael; Majlender, Peter; Hedlund, Turid; Gudnason, Gudni

    2010-06-23

    The Internet has recently made possible the free global availability of scientific journal articles. Open Access (OA) can occur either via OA scientific journals, or via authors posting manuscripts of articles published in subscription journals in open web repositories. So far there have been few systematic studies showing how big the extent of OA is, in particular studies covering all fields of science. The proportion of peer reviewed scholarly journal articles, which are available openly in full text on the web, was studied using a random sample of 1837 titles and a web search engine. Of articles published in 2008, 8.5% were freely available at the publishers' sites. For an additional 11.9% free manuscript versions could be found using search engines, making the overall OA percentage 20.4%. Chemistry (13%) had the lowest overall share of OA, Earth Sciences (33%) the highest. In medicine, biochemistry and chemistry publishing in OA journals was more common. In all other fields author-posted manuscript copies dominated the picture. The results show that OA already has a significant positive impact on the availability of the scientific journal literature and that there are big differences between scientific disciplines in the uptake. Due to the lack of awareness of OA-publishing among scientists in most fields outside physics, the results should be of general interest to all scholars. The results should also interest academic publishers, who need to take into account OA in their business strategies and copyright policies, as well as research funders, who like the NIH are starting to require OA availability of results from research projects they fund. The method and search tools developed also offer a good basis for more in-depth studies as well as longitudinal studies.

  12. Open access to the scientific journal literature: situation 2009.

    Directory of Open Access Journals (Sweden)

    Bo-Christer Björk

    Full Text Available BACKGROUND: The Internet has recently made possible the free global availability of scientific journal articles. Open Access (OA can occur either via OA scientific journals, or via authors posting manuscripts of articles published in subscription journals in open web repositories. So far there have been few systematic studies showing how big the extent of OA is, in particular studies covering all fields of science. METHODOLOGY/PRINCIPAL FINDINGS: The proportion of peer reviewed scholarly journal articles, which are available openly in full text on the web, was studied using a random sample of 1837 titles and a web search engine. Of articles published in 2008, 8.5% were freely available at the publishers' sites. For an additional 11.9% free manuscript versions could be found using search engines, making the overall OA percentage 20.4%. Chemistry (13% had the lowest overall share of OA, Earth Sciences (33% the highest. In medicine, biochemistry and chemistry publishing in OA journals was more common. In all other fields author-posted manuscript copies dominated the picture. CONCLUSIONS/SIGNIFICANCE: The results show that OA already has a significant positive impact on the availability of the scientific journal literature and that there are big differences between scientific disciplines in the uptake. Due to the lack of awareness of OA-publishing among scientists in most fields outside physics, the results should be of general interest to all scholars. The results should also interest academic publishers, who need to take into account OA in their business strategies and copyright policies, as well as research funders, who like the NIH are starting to require OA availability of results from research projects they fund. The method and search tools developed also offer a good basis for more in-depth studies as well as longitudinal studies.

  13. Teaching the Scientific Method Using Current News Articles

    Science.gov (United States)

    Palmer, Laura K.; Mahan, Carolyn G.

    2013-01-01

    We describe a short (less than 50 minutes) activity using news articles from sources such as "Science Daily" to teach students the steps of the scientific method and the difference between primary and secondary literature sources. The flexibility in choosing news articles to examine allowed us to tailor the activity to the specific interests of…

  14. A Computing Environment to Support Repeatable Scientific Big Data Experimentation of World-Wide Scientific Literature

    Energy Technology Data Exchange (ETDEWEB)

    Schlicher, Bob G [ORNL; Kulesz, James J [ORNL; Abercrombie, Robert K [ORNL; Kruse, Kara L [ORNL

    2015-01-01

    A principal tenant of the scientific method is that experiments must be repeatable and relies on ceteris paribus (i.e., all other things being equal). As a scientific community, involved in data sciences, we must investigate ways to establish an environment where experiments can be repeated. We can no longer allude to where the data comes from, we must add rigor to the data collection and management process from which our analysis is conducted. This paper describes a computing environment to support repeatable scientific big data experimentation of world-wide scientific literature, and recommends a system that is housed at the Oak Ridge National Laboratory in order to provide value to investigators from government agencies, academic institutions, and industry entities. The described computing environment also adheres to the recently instituted digital data management plan mandated by multiple US government agencies, which involves all stages of the digital data life cycle including capture, analysis, sharing, and preservation. It particularly focuses on the sharing and preservation of digital research data. The details of this computing environment are explained within the context of cloud services by the three layer classification of Software as a Service , Platform as a Service , and Infrastructure as a Service .

  15. A Review of Scientific Topics and Literature in Abdominal Radiology in Germany - Part 1: Gastrointestinal Tract.

    Science.gov (United States)

    Schreyer, A G; Wessling, J; Kinner, S; Juchems, M S; Holzapfel, K; Lauenstein, T C; Konietzke, P; Grenacher, L

    2016-02-01

    The working group for abdominal and gastrointestinal diagnosis is a group of the German Radiological Society (DRG) focusing clinically and scientifically on the diagnosis and treatment of the gastrointestinal tract with all parenchymatous abdominal organs. In addition to the clinical and scientific further development of abdominal radiology, the education of radiologists within this core discipline of radiology is one of the major aims. In this article we give an up-to-date literature review of scientific radiological topics especially covered by German radiologists. This manuscript focuses on the most recent literature on the diagnosis of the stomach, small bowel, colon and rectum. The review with a focus on the most recent studies published by German radiologists concludes with a synopsis of mesenterial bleeding and ischemia followed by a critical appraisal of the current literature on conventional abdominal radiography. Based on recent literature and guidelines there is a change of paradigms regarding the diagnosis of esophagus and gastric cancer towards CT, which is considered equally to endosonography. For small bowel imaging in Crohn's disease ultrasound as well as MRI with a new focus on DWI are the most important imaging modalities scientifically. For colonic diagnosis virtual colonoscopy has replaced the conventional radiological methods. For staging of rectal carcinoma as well as for therapeutic stratification a high resolution MRI of the pelvis is of paramount interest. Multislice CT is considered the most important modality to assess mesenteric ischemia or bleeding. © Georg Thieme Verlag KG Stuttgart · New York.

  16. [New bibliometric indicators for the scientific literature: an evolving panorama].

    Science.gov (United States)

    La Torre, G; Sciarra, I; Chiappetta, M; Monteduro, A

    2017-01-01

    Bibliometrics is a science which evaluates the impact of the scientific work of a journal or of an author, using mathematical and statistical tools. Impact Factor (IF) is the first bibliometric parameter created, and after it many others have been progressively conceived in order to go beyond its limits. Currently bibliometric indexes are used for academic purposes, among them to evaluate the eligibility of a researcher to compete for the National Scientific Qualification, in order to access to competitive exams to become professor. Aim of this study is to identify the most relevant bibliometric indexes and to summarized their characteristics. A revision of bibliometric indexes as been conducted, starting from the classic ones and completing with the most recent ones. The two most used bibliometric indexes are the IF, which measures the scientific impact of a periodical and bases on Web of Science citation database, and the h-index, which measures the impact of the scientific work of a researcher, basing on Scopus database. Besides them other indexes have been created more recently, such as the SCImago Journal Rank Indicator (SJR), the Source Normalised Impact per Paper (SNIP) and the CiteScore index. They are all based on Scopus database and evaluate, in different ways, the citational impact of a periodic. The i10-index instead is provided from Google Scholar database and allows to evaluate the impact of the scientific production of a researcher. Recently two softwares have been introduced: the first one, Publish or Perish, allows to evaluate the scientific work of a researcher, through the assessment of many indexes; the second one, Altmetric, measure the use in the Web of the academic papers, instead of measuring citations, by means of alternative metrics respect to the traditional ones. Each analized index shows advantages but also criticalities. Therefore the combined use of more than one indexes, citational and not, should be preferred, in order to correctly

  17. Using crowdsourcing to evaluate published scientific literature: methods and example.

    Directory of Open Access Journals (Sweden)

    Andrew W Brown

    Full Text Available Systematically evaluating scientific literature is a time consuming endeavor that requires hours of coding and rating. Here, we describe a method to distribute these tasks across a large group through online crowdsourcing. Using Amazon's Mechanical Turk, crowdsourced workers (microworkers completed four groups of tasks to evaluate the question, "Do nutrition-obesity studies with conclusions concordant with popular opinion receive more attention in the scientific community than do those that are discordant?" 1 Microworkers who passed a qualification test (19% passed evaluated abstracts to determine if they were about human studies investigating nutrition and obesity. Agreement between the first two raters' conclusions was moderate (κ = 0.586, with consensus being reached in 96% of abstracts. 2 Microworkers iteratively synthesized free-text answers describing the studied foods into one coherent term. Approximately 84% of foods were agreed upon, with only 4 and 8% of ratings failing manual review in different steps. 3 Microworkers were asked to rate the perceived obesogenicity of the synthesized food terms. Over 99% of responses were complete and usable, and opinions of the microworkers qualitatively matched the authors' expert expectations (e.g., sugar-sweetened beverages were thought to cause obesity and fruits and vegetables were thought to prevent obesity. 4 Microworkers extracted citation counts for each paper through Google Scholar. Microworkers reached consensus or unanimous agreement for all successful searches. To answer the example question, data were aggregated and analyzed, and showed no significant association between popular opinion and attention the paper received as measured by Scimago Journal Rank and citation counts. Direct microworker costs totaled $221.75, (estimated cost at minimum wage: $312.61. We discuss important points to consider to ensure good quality control and appropriate pay for microworkers. With good

  18. Searching the scientific literature: implications for quantitative and qualitative reviews.

    Science.gov (United States)

    Wu, Yelena P; Aylward, Brandon S; Roberts, Michael C; Evans, Spencer C

    2012-08-01

    Literature reviews are an essential step in the research process and are included in all empirical and review articles. Electronic databases are commonly used to gather this literature. However, several factors can affect the extent to which relevant articles are retrieved, influencing future research and conclusions drawn. The current project examined articles obtained by comparable search strategies in two electronic archives using an exemplar search to illustrate factors that authors should consider when designing their own search strategies. Specifically, literature searches were conducted in PsycINFO and PubMed targeting review articles on two exemplar disorders (bipolar disorder and attention deficit/hyperactivity disorder) and issues of classification and/or differential diagnosis. Articles were coded for relevance and characteristics of article content. The two search engines yielded significantly different proportions of relevant articles overall and by disorder. Keywords differed across search engines for the relevant articles identified. Based on these results, it is recommended that when gathering literature for review papers, multiple search engines should be used, and search syntax and strategies be tailored to the unique capabilities of particular engines. For meta-analyses and systematic reviews, authors may consider reporting the extent to which different archives or sources yielded relevant articles for their particular review.

  19. Introducing Pre-University Students to Primary Scientific Literature through Argumentation Analysis

    Science.gov (United States)

    Koeneman, Marcel; Goedhart, Martin; Ossevoort, Miriam

    2013-01-01

    Primary scientific literature is one of the most important means of communication in science, written for peers in the scientific community. Primary literature provides an authentic context for showing students how scientists support their claims. Several teaching strategies have been proposed using (adapted) scientific publications, some for…

  20. National scientific literature on nursing ethics: a systematic Review

    Directory of Open Access Journals (Sweden)

    Ilka Nicéia D’Aquino Oliveira Teixeira

    2010-03-01

    Full Text Available Objective: To identify the most prevalent nursing ethical issues published in scientific Brazilian journals. Methods: A systematic literature review with the following inclusion criteria: (1 articles on Nursing Ethics written in Portuguese, English, French, and Spanish; (2 published in Brazilian journals; (3 in the period from January 1997 to February 2009. The search was carried out in four databases BDENF, LILACS, MEDLINE, and SCIELO. The key-words were ethics AND nursing. The selected studies were classified into categories. The content of the articles were analyzed using the Collective Subject Discourse. The categories generated discourses by organizing the main excerpts from the abstracts of the selected studies, which are the “key expressions”. Results: A hundred and thirty three articles that met the inclusion criteria were classified into eight categories: 1. Nursing Care; 2. Dilemmas and Controversies; 3. Education; 4. Legal Aspects; 5. Research; 6. Management; 7. Values and Beliefs; 8. Perspectives and Health Policies. The category “Nursing Care” prevailed in 36% of the selected articles, and it was classified into six subcategories. “Dilemmas and Controversies” was the second most prevalent category (15%. Conclusion: The number of theoretical papers on ethical issues is high, but there is little research on the ethical experiences in nursing practice.

  1. A review of scientific topics and literature in abdominal radiology in Germany. Pt. 1. Gastrointestinal tract; Aktuelle Schwerpunkte und Literatur der Abdominalradiologie im deutschsprachigen Raum. T. 1. Gastrointestinaltrakt

    Energy Technology Data Exchange (ETDEWEB)

    Schreyer, A.G. [University Hospital Regensburg (Germany). Dept. of Radiology; Wessling, J. [Clemens Hospital, Muenster (Germany). Clinic for Radiology; Kinner, S.; Lauenstein, T.C. [University Hospital Essen (Germany). Dept. of Radiology; Juchems, M.S. [Konstanz Hospital (Germany). Dept. of Diagnostic and Interventional Radiology; Holzapfel, K. [Technical University Munich (Germany). Inst. of Radiology; Konietzke, P. [University Hospital Heidelberg (Germany). Dept. of Diagnostic and Interventional Radiology; Grenacher, L. [Diagnostic Muenchen - Diagnostic Imaging Center, Munich (Germany)

    2016-02-15

    The working group for abdominal and gastrointestinal diagnosis is a group of the German Radiological Society (DRG) focusing clinically and scientifically on the diagnosis and treatment of the gastrointestinal tract with all parenchymatous abdominal organs. In addition to the clinical and scientific further development of abdominal radiology, the education of radiologists within this core discipline of radiology is one of the major aims. In this article we give an up-to-date literature review of scientific radiological topics especially covered by German radiologists. This manuscript focuses on the most recent literature on the diagnosis of the stomach, small bowel, colon and rectum. The review with a focus on the most recent studies published by German radiologists concludes with a synopsis of mesenterial bleeding and ischemia followed by a critical appraisal of the current literature on conventional abdominal radiography.

  2. Introducing Pre-university Students to Primary Scientific Literature Through Argumentation Analysis

    NARCIS (Netherlands)

    Koeneman, Marcel; Goedhart, Martin; Ossevoort, Miriam

    2013-01-01

    Primary scientific literature is one of the most important means of communication in science, written for peers in the scientific community. Primary literature provides an authentic context for showing students how scientists support their claims. Several teaching strategies have been proposed using

  3. 76 FR 59407 - Center for Biologics Evaluation and Research Report of Scientific and Medical Literature and...

    Science.gov (United States)

    2011-09-26

    ... ``Center for Biologics Evaluation and Research Report of Scientific and Medical Literature and Information... HUMAN SERVICES Food and Drug Administration Center for Biologics Evaluation and Research Report of Scientific and Medical Literature and Information on Non-Standardized Allergenic Extracts in the Diagnosis...

  4. An annotated bibliography of scientific literature on managing forests for carbon benefits

    Science.gov (United States)

    Sarah J. Hines; Linda S. Heath; Richard A. Birdsey

    2010-01-01

    Managing forests for carbon benefits is a consideration for climate change, bioenergy, sustainability, and ecosystem services. A rapidly growing body of scientific literature on forest carbon management includes experimental, modeling, and synthesis approaches, at the stand- to landscape- to continental-level. We conducted a search of the scientific literature on the...

  5. Introducing Pre-university Students to Primary Scientific Literature Through Argumentation Analysis

    NARCIS (Netherlands)

    Koeneman, Marcel; Goedhart, Martin; Ossevoort, Miriam

    2013-01-01

    Primary scientific literature is one of the most important means of communication in science, written for peers in the scientific community. Primary literature provides an authentic context for showing students how scientists support their claims. Several teaching strategies have been proposed using

  6. Testing Literature: The Current State of Affairs. ERIC Digest.

    Science.gov (United States)

    Purves, Alan C.

    A synthesis of the report, "The Current State of Assessment in Literature," (produced by the Center for the Learning and Teaching of Literature), this digest discusses methods of evaluating students' knowledge of literature. The digest argues that, by and large, the tests that now exist in the United States do not live up to the standards set by…

  7. The Using Condition of Interactive Reading Strategy in Reading Scientif-ic and Technological English Literature of Postgraduates of Engineering

    Institute of Scientific and Technical Information of China (English)

    SU Hong; CUI Xiao-ling

    2014-01-01

    In the reading process and after reading of the scientific and technological English literature for postgraduates of engi-neering, there are several barriers like the understanding of the vocabulary, the analyzing the complex sentences and the grasping the whole texts. This paper tries to investigate the using condition of interactive reading strategy in reading scientific and techno-logical English literature of postgraduates of engineering. The study reveals that postgraduates of engineering frequently using some of strategies of the interactive reading strategy, but the overall using condition is only in the average level, and is not so flexi-ble.

  8. 76 FR 71045 - Center for Biologics Evaluation and Research Report of Scientific and Medical Literature and...

    Science.gov (United States)

    2011-11-16

    ... Scientific and Medical Literature and Information on Non-Standardized Allergenic Extracts in the Diagnosis... literature and information concerning the use of non- standardized allergenic extracts in the diagnosis and... Literature and Information on Non-Standardized Allergenic Extracts in the Diagnosis and Treatment of...

  9. Searching for a Common Ground--A Literature Review of Empirical Research on Scientific Inquiry Activities

    Science.gov (United States)

    Rönnebeck, Silke; Bernholt, Sascha; Ropohl, Mathias

    2016-01-01

    Despite the importance of scientific inquiry in science education, researchers and educators disagree considerably regarding what features define this instructional approach. While a large body of literature addresses theoretical considerations, numerous empirical studies investigate scientific inquiry on quite different levels of detail and also…

  10. Introducing Pre-university Students to Primary Scientific Literature Through Argumentation Analysis

    Science.gov (United States)

    Koeneman, Marcel; Goedhart, Martin; Ossevoort, Miriam

    2013-01-01

    Primary scientific literature is one of the most important means of communication in science, written for peers in the scientific community. Primary literature provides an authentic context for showing students how scientists support their claims. Several teaching strategies have been proposed using (adapted) scientific publications, some for secondary education, but none of these strategies focused specifically on scientific argumentation. The purpose of this study is to evaluate a strategy for teaching pre-university students to read unadapted primary scientific literature, translated into students' native language, based on a new argumentation analysis framework. This framework encompasses seven types of argumentative elements: motive, objective, main conclusion, implication, support, counterargument and refutation. During the intervention, students studied two research articles. We monitored students' reading comprehension and their opinion on the articles and activities. After the intervention, we measured students' ability to identify the argumentative elements in a third unadapted and translated research article. The presented framework enabled students to analyse the article by identifying the motive, objective, main conclusion and implication and part of the supports. Students stated that they found these activities useful. Most students understood the text on paragraph level and were able to read the article with some help for its vocabulary. We suggest that primary scientific literature has the potential to show students important aspects of the scientific process and to learn scientific vocabulary in an authentic context.

  11. Neuroimaging of Central Sensitivity Syndromes: Key Insights from the Scientific Literature.

    Science.gov (United States)

    Walitt, Brian; Ceko, Marta; Gracely, John L; Gracely, Richard H

    2016-01-01

    Central sensitivity syndromes are characterized by distressing symptoms, such as pain and fatigue, in the absence of clinically obvious pathology. The scientific underpinnings of these disorders are not currently known. Modern neuroimaging techniques promise new insights into mechanisms mediating these postulated syndromes. We review the results of neuroimaging applied to five central sensitivity syndromes: fibromyalgia, chronic fatigue syndrome, irritable bowel syndrome, temporomandibular joint disorder, and vulvodynia syndrome. Neuroimaging studies of basal metabolism, anatomic constitution, molecular constituents, evoked neural activity, and treatment effect are compared across all of these syndromes. Evoked sensory paradigms reveal sensory augmentation to both painful and nonpainful stimulation. This is a transformative observation for these syndromes, which were historically considered to be completely of hysterical or feigned in origin. However, whether sensory augmentation represents the cause of these syndromes, a predisposing factor, an endophenotype, or an epiphenomenon cannot be discerned from the current literature. Further, the result from cross-sectional neuroimaging studies of basal activity, anatomy, and molecular constituency are extremely heterogeneous within and between the syndromes. A defining neuroimaging "signature" cannot be discerned for any of the particular syndromes or for an over-arching central sensitization mechanism common to all of the syndromes. Several issues confound initial attempts to meaningfully measure treatment effects in these syndromes. At this time, the existence of "central sensitivity syndromes" is based more soundly on clinical and epidemiological evidence. A coherent picture of a "central sensitization" mechanism that bridges across all of these syndromes does not emerge from the existing scientific evidence.

  12. [Death education for nursing professors and students: a document review of the scientific literature].

    Science.gov (United States)

    dos Santos, Janaina Luiza; Bueno, Sonia Maria Villela

    2011-03-01

    In Western cultures, Death is not among the favorite topics. Nevertheless, how should professionals who deal with Death on a daily basis behave? What meaning does Death have to them? This study consists of a survey on scientific literature about the referred subject in nursing education. Using a qualitative method, a documentary exploratory study was performed, characterized by a survey over a five-year period. The following keywords were used: Nursing Professor and Student, Death and Dying. Twelve articles were located and comprised three categories: Nursing students and dealing with death every day; The nursing professor dealing with death every day and the teaching skills; Academic education providing support for a critical-reflexive view about death-dying. In conclusion, there is o preparation for nursing students on the referred theme. Changing the current situation is only possible with greater investments and if further studies are performed.

  13. Fishes and other aquatic species in the Byzantine literature. Classification, terminology and scientific names.

    Directory of Open Access Journals (Sweden)

    Maria CHRONE-VAKALOPOULOS

    2009-01-01

    Full Text Available Fishes and other aquatic species were substantial food in the every day life of Byzantine people. The predomination of Christianity contributed to the increased consumption of fishes and other seafood compared to the meat of land animals and chicken. More than a hundred ten names of fishes and about thirty names of other aquatic organisms are found in the sources of the Byzantine literature. Most frequent references are found in the medical texts of the Byzantine doctors, where, fishes are classified in categories depending on their physiology and origin, because, according to the writers, these are determining factors for the evaluation of the nutritional value of each species.The purpose of this study is to present the terminology of the fishes and the various aquatic species that are found in the Byzantine sources and to identify, in parallel, each species with its current scientific name.  

  14. The scientific literature on audit and quality of nursing records

    Directory of Open Access Journals (Sweden)

    Cecília Nogueira Valença

    2013-11-01

    Full Text Available Objetivos: Conhecer a produção científica sobre auditoria em enfermagem e identificar a importância do registro de enfermagem no prontuário para a auditoria. Método: Revisão bibliográfica narrativa, para qual selecionou-se artigos relacionados à auditoria em enfermagem e registros de enfermagem nas bases eletrônicas Scientific Electronic Library Online, e Literatura Latinoamericana e do Caribe em Ciências da Saúde, publicados entre 2000 e 2010. Resultados: Os artigos analisados sob caráter qualitativo indicaram que há poucos estudos sobre a temática. Foi identificado que auditoria de enfermagem, atualmente, é realizada pelo método retrospectivo no prontuário e está voltada para o âmbito contábil, e que os registros de enfermagem possuem qualidade insatisfatória para servir de instrumento de coleta de dados. Conclusão: Há perspectivas que a auditoria passe a investigar a qualidade do cuidado, e possuir um caráter educativo que possibilite a qualidade da assistência.

  15. Scholarly literature and the press: scientific impact and social perception of physics computing

    CERN Document Server

    Pia, Maria Grazia; Bell, Zane W; Dressendorfer, Paul V

    2014-01-01

    The broad coverage of the search for the Higgs boson in the mainstream media is a relative novelty for high energy physics (HEP) research, whose achievements have traditionally been limited to scholarly literature. This paper illustrates the results of a scientometric analysis of HEP computing in scientific literature, institutional media and the press, and a comparative overview of similar metrics concerning representative particle physics measurements. The picture emerging from these scientometric data documents the scientific impact and social perception of HEP computing. The results of this analysis suggest that improved communication of the scientific and social role of HEP computing would be beneficial to the high energy physics community.

  16. Sustainable Development: The Role of Scientific Literature in Dutch Municipal Spatial Planning

    NARCIS (Netherlands)

    Vroom, Lucas; van Straalen, F.M.

    2016-01-01

    The objective of this article is to show how Dutch municipalities use scientific literature about sustainable development in their spatial planning policies and processes. The approach to this research is twofold. First, we conducted a literature review that summarized the most important discourses

  17. Sustainable Development: The Role of Scientific Literature in Dutch Municipal Spatial Planning

    NARCIS (Netherlands)

    Vroom, Lucas; van Straalen, F.M.

    The objective of this article is to show how Dutch municipalities use scientific literature about sustainable development in their spatial planning policies and processes. The approach to this research is twofold. First, we conducted a literature review that summarized the most important discourses

  18. A Bibliometric Study of Scientific Literature of Psychiatry in Scopus

    Directory of Open Access Journals (Sweden)

    Maryam Moghadami

    2016-03-01

    Full Text Available ​Background and Objectives : Due to the large proportion of mental health problems and psychiatric disorders, research in the field of mental health is of great significance. The main objective of this study was to investigate the scientific productivity in the field of psychiatry in the Scopus database (2000-2012. Material and Methods : In this study, we tried to examine 27,516 records of articles which were published in Scopus databases during 2000-2012. Then, by using scientometric method, we surveyed authors, active institutes and leading countries in this field and along side, core journals were studied in journal citation report by using impact factor. Results : The results showed that the United States of America, England and Germany are the top countries in the field of psychiatry. Also, there are 40 core journals in this field which have an impact factor higher than 3. London Kings College with 565 articles, VA Medical Center with a total of 534 articles and Harvard Medical School with 289 articles are on the top of active institutions in the field of psychiatry. In Iran, Tehran University of Medical Sciences with 37 articles, Shiraz University of Medical Sciences with 16 articles and Isfahan University of Medical Sciences with 9 articles were the most active universities in Iran in publishing articles. Among international authors, Biederman with13% of the articles, Birmaher with12% and Vitiello with11% have a considerable role in publishing in this field. In Iran Mohammadi with  9 articles, Akhundzade with 8 articles and Amini and Qanizadeh with 7 articles were active researchers. In comparison with other countries, Iran has a light portion of the research in this field but it has shown a growing trend in publishing in recent years. Conclusion : The results of this research can be used as evidence for researchers to determine the path ahead in research and as a tool for strategic planning used in the mental health sector.

  19. Migration and gender in the mexican context: scientific literature review

    Directory of Open Access Journals (Sweden)

    Teresa Rebolledo Gámez

    2014-07-01

    Full Text Available Female migration is a phenomenon with socioeducational considerations thar determine their analysis.The prensent article presents a literature review aims to analyze the aspect thar are discussed in relation to the issue of migration and gender in Mexico. Therefore, it has selected more than forty articles from magazines, discussion forums and books in the last decade hace collected reflexions and research on this reality. As a result of this review, it has taken three areas in the contributions published: Human Rights and policy migratory; female migration characteristics; and vulnerability and risk situation. Despite the thematic diversity, appear repeatedly ideas like the idiosyncasies of female migration, vulnerability and risk assumed by women in border transit and the violation of rights of women to political and institutional level.Received: 04/12/2013 / Accepted: 17/01/2014How to reference this articleRebolledo Gámez, T., Rodríguez Casado, M. R. (2014. Migraciones y género en el contexto mexicano: revisión de la literatura científica. Foro de Educación, 12(17, pp. 165-185. doi: http://dx.doi.org/10.14516/fde.2014.012.017.008

  20. Bibliometric analysis of scientific literature on intestinal parasites in Argentina during the period 1985-2014.

    Science.gov (United States)

    Basualdo, Juan A; Grenóvero, María S; Bertucci, Evangelina; Molina, Nora B

    2016-01-01

    The study of scientific production is a good indicator of the progress in research and knowledge generation. Bibliometrics is a scientific discipline that uses a set of indicators to quantitatively express the bibliographic characteristics of scientific publications. The scientific literature on the epidemiology of intestinal parasites in Argentina is scattered in numerous sources, hindering access and visibility to the scientific community. Our purpose was to perform a quantitative, bibliometric study of the scientific literature on intestinal parasites in humans in Argentina published in the period 1985-2014. This bibliometric analysis showed an increase in the number of articles on intestinal parasites in humans in Argentina published over the past 30 years. Those articles showed a collaboration index similar to that of the literature, with a high index of institutionality for national institutions and a very low one for international collaboration. The original articles were published in scientific journals in the American Continent, Europe and Asia. The use of bibliometric indicators can provide a solid tool for the diagnosis and survey of the research on epidemiology of intestinal parasites and contributes to the dissemination and visibility of information on the scientific production developed in Argentina. Copyright © 2016 Asociación Argentina de Microbiología. Publicado por Elsevier España, S.L.U. All rights reserved.

  1. MememxGATE: Unearthing Latent Content Features for Improved Search and Relevancy Ranking Across Scientific Literature

    Science.gov (United States)

    Wilson, B. D.; McGibbney, L. J.; Mattmann, C. A.; Ramirez, P.; Joyce, M.; Whitehall, K. D.

    2015-12-01

    Quantifying scientific relevancy is of increasing importance to NASA and the research community. Scientific relevancy may be defined by mapping the impacts of a particular NASA mission, instrument, and/or retrieved variables to disciplines such as climate predictions, natural hazards detection and mitigation processes, education, and scientific discoveries. Related to relevancy, is the ability to expose data with similar attributes. This in turn depends upon the ability for us to extract latent, implicit document features from scientific data and resources and make them explicit, accessible and useable for search activities amongst others. This paper presents MemexGATE; a server side application, command line interface and computing environment for running large scale metadata extraction, general architecture text engineering, document classification and indexing tasks over document resources such as social media streams, scientific literature archives, legal documentation, etc. This work builds on existing experiences using MemexGATE (funded, developed and validated through the DARPA Memex Progrjam PI Mattmann) for extracting and leveraging latent content features from document resources within the Materials Research domain. We extend the software functionality capability to the domain of scientific literature with emphasis on the expansion of gazetteer lists, named entity rules, natural language construct labeling (e.g. synonym, antonym, hyponym, etc.) efforts to enable extraction of latent content features from data hosted by wide variety of scientific literature vendors (AGU Meeting Abstract Database, Springer, Wiley Online, Elsevier, etc.) hosting earth science literature. Such literature makes both implicit and explicit references to NASA datasets and relationships between such concepts stored across EOSDIS DAAC's hence we envisage that a significant part of this effort will also include development and understanding of relevancy signals which can ultimately

  2. Improve nursing in evidence-based practice: How Chinese nurses' read and comprehend scientific literature

    Directory of Open Access Journals (Sweden)

    Fei-Fei Huang

    2017-07-01

    Conclusions: The survey of the current status of literature education among Chinese nurses suggests that providing protected time, training for critical thinking, and incentive mechanisms will help improve nurses' engagement in literature and create a culture of academic inquiry.

  3. Cholesterol lowering effect of a commercial margarine in hypercholesterolemic adults: a review of the scientific literature.

    Directory of Open Access Journals (Sweden)

    Raquel Bernácer

    2013-03-01

    Full Text Available Introduction: the hypercholesterolemia is a growing problem, responsible of one fifth of coronary events in Spain. It is considered that plant sterols (PS could play an important role in their treatment.Objective: we review the role of a range of functional foods with added PS (including specific studies using Flora pro•activ in adults with hypercholesterolemia.Methods: we performed a review of the literature in the PubMed database to locate human studies that have evaluated the role of Flora pro•activ or PS fortified foods with a similar composition. We also have been consulted the European Food Safety Authority (EFSA database.Results: Flora pro•activ demonstrated in rigorous scientific studies to lower cholesterol in adults with hypercholesterolemia. Two servings of Flora pro•activ (1.5 g PS are needed to observe this effect. Lowering cholesterol with Flora pro•activ (2 servings / day oscillate as EFSA notes, between 7 and 10%. This effect is observed after 2-3 weeks. Its composition allows to make health claims about lowering cholesterol as is described for the European Union. The cholesterol-lowering efficacy of PS enriched foods that are not margarine, mayonnaise, salad dressings or dairy products is under-researched. With few exceptions, the use of fortified foods with PS is safe.Conclusions: the current scientific evidence justify the promotion of the use of PS to lower LDL cholesterol in adults with hypercholesterolemia.

  4. Trends and biases in global scientific literature about ecological niche models.

    Science.gov (United States)

    Vaz, U L; Cunha, H F; Nabout, J C

    2015-11-01

    Recently, ecological niche models have been employed to investigate the potential geographical distribution of species. However, it is necessary to analyze the vast number of publications on this topic to understand the trends and biases of research using ecological niche models (ENMs). Therefore, this study aims to investigate trends in the scientific literature regarding studies on ENMs. For the quantitative analysis of the literature on ENMs, we performed a search in the Thomson ISI (Web of Science) database between 1991 and 2013. The search identified 3042 papers containing preselected keywords in either the title or abstract. The results showed that the number of papers has increased over the years (r=0.77, Pplants (402 papers, or 28.36% of the total). There was no relationship between the modeling method used and the taxonomic group studied (χ2=4.8, P=0.15). Finally, the wide availability of biological, environmental and computational resources has elicited the broad use of tools for ENMs. Despite the conceptual discussions of the ENMs, this method is currently the most effective way to evaluate the potential geographical distribution of species, and to predict the distribution under different environmental conditions (i.e., future or past scenarios).

  5. Creating Value through Virtual Teams: A Current Literature Review

    Directory of Open Access Journals (Sweden)

    Akemi Takeoka Chatfield

    2014-11-01

    Full Text Available Globally, virtual teams (VT as ICT-enabled emergent network organisation forms have gained international validity by innovative organisations, with a corresponding surge of interest in understanding how organisations can leverage VT to create business value. Despite growing deliberations in VT literature on managing VT, tasks and outcomes, however, creating business value through VT remains an unresolved theoretical and pragmatic conundrum. A review of prior relevant literature is essential to advancing knowledge. The paucity of published review articles seems to have impeded the field’s accumulation of VT knowledge. This research, therefore, reviews the current literature on case studies of VT to address the question: What are organisational challenges in creating business value through VT in the organisation? The key challenges found in the literature are effective communication, knowledge sharing, trust, and interpersonal skills in the new virtual boundary-less environment. Drawing on the IT business value model, we also discuss their resource-based implications.

  6. How to Use Current Medical Literature and APA Format Style.

    Science.gov (United States)

    Peek, Robin

    Directives and guidance in obtaining current medical literature are provided in this publication with special emphasis given to locating material in the Portland, Oregon area. The uses and types of periodical indexes are identified and periodical index citation examples are indicated. Explanations are offered on: (1) how to conduct an effective…

  7. How to Use Current Medical Literature and APA Format Style.

    Science.gov (United States)

    Peek, Robin

    Directives and guidance in obtaining current medical literature are provided in this publication with special emphasis given to locating material in the Portland, Oregon area. The uses and types of periodical indexes are identified and periodical index citation examples are indicated. Explanations are offered on: (1) how to conduct an effective…

  8. Benefits and harms of general health checks- lifelong learning in general practice: how to read and use scientific literature

    DEFF Research Database (Denmark)

    Arreskov, Anne Beiter; Graungaard, Anette Hauskov; Nielsen, Kirsten Lykke

    the paper using the method of critical appraisal. Session content The didactic method used in the workshop is mostly small group activities with eight participants and two tutors in each group. The participants will receive two scientific papers: the BMJ-version of the Cochrane review about general health......Abstract title: Benefits and harms of general health checks - lifelong learning in general practice: how to read and use scientific literature Objectives After this workshop the participants will know the basics of how to read a systematic literature review and interpret a meta-analysis and be able......, assesses, and implements methods of diagnosis and treatment on the basis of the best available current research, clinical expertise, and combines this with the needs and preferences of the patient, is termed evidence-based medicine. By learning and practising the principles of evidence-based medicine, GPs...

  9. Analysis of scientific production archival science in brazil: a literature review

    Directory of Open Access Journals (Sweden)

    José Mauro Gouveia de Medeiros

    2016-12-01

    Full Text Available Introduction: review of the literature resulting from bibliographic survey about the scientific literature of archives in Brazil. Objective: to identify aspects of scientific literature of archival science, through bibliographical research, that aims to introduce the features of the archival science in Brazil. Methodology: Brazilian sites, databases and reference services were used as sources to identify 523 references. 15 texts were selected and analyzed with respect to authorship, affiliation, publication year, publication type, type and size of sources used, methodology, geographical range, results, among other aspects. Results: the scientific articles were the main object of study; the book was the most cited channel; the journal Arquivo & Administração and Encontro Nacional de Pesquisa em Ciência da Informação have importance on the national scene; Rio de Janeiro is the geographic region with greater production; There has been growth in the number of works since the 2007 and increased collaboration. Conclusions: the interest in Archival Science literature is increasing significantly; there was diversification of the publishing channels, mainly works of events and articles since 2013; the Archival Science is consolidating in Brazil with an increasing production, collaboration and interest in its scientific literature.

  10. Citations, References and the Growth of Scientific Literature: A Model of Dynamic Interaction

    Science.gov (United States)

    Krauze, Tadeusz K.; Hillinger, Claude

    1971-01-01

    A mathematical model is presented which explains the observed exponential growth rates of citations and references in a scientific discipline. The independent variables are the growth rate of the number of articles published and the decay rate of citation of old literature. (13 references) (Author)

  11. CREATE Cornerstone: Introduction to Scientific Thinking, a New Course for STEM-Interested Freshmen, Demystifies Scientific Thinking through Analysis of Scientific Literature

    Science.gov (United States)

    Gottesman, Alan J.; Hoskins, Sally G.

    2013-01-01

    The Consider, Read, Elucidate hypotheses, Analyze and interpret data, Think of the next Experiment (CREATE) strategy for teaching and learning uses intensive analysis of primary literature to improve students’ critical-thinking and content integration abilities, as well as their self-rated science attitudes, understanding, and confidence. CREATE also supports maturation of undergraduates’ epistemological beliefs about science. This approach, originally tested with upper-level students, has been adapted in Introduction to Scientific Thinking, a new course for freshmen. Results from this course's initial semesters indicate that freshmen in a one-semester introductory course that uses a narrowly focused set of readings to promote development of analytical skills made significant gains in critical-thinking and experimental design abilities. Students also reported significant gains in their ability to think scientifically and understand primary literature. Their perceptions and understanding of science improved, and multiple aspects of their epistemological beliefs about science gained sophistication. The course has no laboratory component, is relatively inexpensive to run, and could be adapted to any area of scientific study. PMID:23463229

  12. TASER® conducted electrical weapons: misconceptions in the scientific/medical and other literature.

    Science.gov (United States)

    Jauchem, James R

    2015-03-01

    TASER(®) conducted electrical weapons (CEWs) have become an important law-enforcement tool. Controversial questions are often raised during discussion of some incidents in which the devices have been used. The main purpose of this paper is to point out some misconceptions about CEWs that have been published in the scientific/medical and other literature. This is a narrative review, using a multidisciplinary approach of analyzing reports from scientific/medical and other literature sources. In previous reports, durations of incapacitating effects and possible associations of CEWs with deaths-in-custody have often been overstated or exaggerated. Comparisons of CEW effects with "electrocution" are misleading. Clarification of these misconceptions may be important during policymaker decisions, practitioner operations, expert witness testimonies, and court proceedings. Despite misconceptions in the literature, CEWs can still be a valuable tool for law enforcement activities. Scientists, medical professionals, legal advisors, and investigators of police tactics should be aware of these misconceptions.

  13. C-Rank: A Link-based Similarity Measure for Scientific Literature Databases

    CERN Document Server

    Yoon, Seok-Ho; Park, Sunju

    2011-01-01

    As the number of people who use scientific literature databases grows, the demand for literature retrieval services has been steadily increased. One of the most popular retrieval services is to find a set of papers similar to the paper under consideration, which requires a measure that computes similarities between papers. Scientific literature databases exhibit two interesting characteristics that are different from general databases. First, the papers cited by old papers are often not included in the database due to technical and economic reasons. Second, since a paper references the papers published before it, few papers cite recently-published papers. These two characteristics cause all existing similarity measures to fail in at least one of the following cases: (1) measuring the similarity between old, but similar papers, (2) measuring the similarity between recent, but similar papers, and (3) measuring the similarity between two similar papers: one old, the other recent. In this paper, we propose a new ...

  14. Searching for Animal Sentience: A Systematic Review of the Scientific Literature

    Science.gov (United States)

    Proctor, Helen S.; Carder, Gemma; Cornish, Amelia R.

    2013-01-01

    Simple Summary The emotional lives of animals is often doubted and questioned. Due to the subjective nature of animal emotions, many think that they are out of the reach of scientific measurement. In this systematic review, of over two decades of scientific literature, we found that this was not actually the case. By using a list of keywords, formed of both positive and negative emotions, and terminology relating to animal sentience, we reviewed the scientific literature. We found that the subjective lives of animals are not only a vital part of human medical research but are regularly measured and studied with scientific rigor. Abstract Knowledge of animal sentience is fundamental to many disciplines and imperative to the animal welfare movement. In this review, we examined what is being explored and discussed, regarding animal sentience, within the scientific literature. Rather than attempting to extract meaning from the many complex and abstract definitions of animal sentience, we searched over two decades of scientific literature using a peer-reviewed list of 174 keywords. The list consisted of human emotions, terminology associated with animal sentience, and traits often thought to be indicative of subjective states. We discovered that very little was actually being explored, and instead there was already much agreement about what animals can feel. Why then is there so much scepticism surrounding the science of animal sentience? Sentience refers to the subjective states of animals, and so is often thought to be impossible to measure objectively. However, when we consider that much of the research found to accept and utilise animal sentience is performed for the development of human drugs and treatment, it appears that measuring sentience is, after all, not quite as impossible as was previously thought. In this paper, we explored what has been published on animal sentience in the scientific literature and where the gaps in research lie. We drew conclusions on

  15. Antibiotic resistance in primary care in Austria - a systematic review of scientific and grey literature

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    Hoffmann Kathryn

    2011-11-01

    Full Text Available Abstract Background Antibiotic resistance is an increasing challenge for health care services worldwide. While up to 90% of antibiotics are being prescribed in the outpatient sector recommendations for the treatment of community-acquired infections are usually based on resistance findings from hospitalized patients. In context of the EU-project called "APRES - the appropriateness of prescribing antibiotic in primary health care in Europe with respect to antibiotic resistance" it was our aim to gain detailed information about the resistance data from Austria in both the scientific and the grey literature. Methods A systematic review was performed including scientific and grey literature published between 2000 and 2010. Inclusion and exclusion criteria were defined and the review process followed published recommendations. Results Seventeen scientific articles and 23 grey literature documents could be found. In contrast to the grey literature, the scientific publications describe only a small part of the resistance situation in the primary health care sector in Austria. Merely half of these publications contain data from the ambulatory sector exclusively but these data are older than ten years, are very heterogeneous concerning the observed time period, the number and origin of the isolates and the kind of bacteria analysed. The grey literature yields more comprehensive and up-to-date information of the content of interest. These sources are available in German only and are not easily accessible. The resistance situation described in the grey literature can be summarized as rather stable over the last two years. For Escherichia coli e.g. the highest antibiotic resistance rates can be seen with fluorochiniolones (19% and trimethoprim/sulfamethoxazole (27%. Conclusion Comprehensive and up-to-date antibiotic resistance data of different pathogens isolated from the community level in Austria are presented. They could be found mainly in the grey

  16. Workplace Interventions to Prevent Disability from Both the Scientific and Practice Perspectives: A Comparison of Scientific Literature, Grey Literature and Stakeholder Observations.

    Science.gov (United States)

    Williams-Whitt, Kelly; Bültmann, Ute; Amick, Benjamin; Munir, Fehmidah; Tveito, Torill H; Anema, Johannes R

    2016-12-01

    Purpose The significant individual and societal burden of work disability could be reduced if supportive workplace strategies could be added to evidence-based clinical treatment and rehabilitation to improve return-to-work (RTW) and other disability outcomes. The goal of this article is to summarize existing research on workplace interventions to prevent disability, relate these to employer disability management practices, and recommend future research priorities. Methods The authors participated in a year-long collaboration that ultimately led to an invited 3-day conference, Improving Research of Employer Practices to Prevent Disability, held October 14-16, 2015, in Hopkinton, Massachusetts, USA. The collaboration included a topical review of the literature, group conference calls to identify key areas and challenges, drafting of initial documents, review of industry publications, and a conference presentation that included feedback from peer researchers and a question/answer session with an expert panel with direct employer experience. Results Evidence from randomized trials and other research designs has shown general support for job modification, RTW coordination, and organizational support, but evidence is still lacking for interventions at a more granular level. Grey literature reports focused mainly on job re-design and work organization. Panel feedback focused on organizational readiness and the beliefs and values of senior managers as critical factors in facilitating changes to disability management practices. While the scientific literature is focused on facilitating improved coping and reducing discomforts for individual workers, the employer-directed grey literature is focused on making group-level changes to policies and procedures. Conclusions Future research might better target employer practices by tying interventions to positive workplace influences and determinants, by developing more participatory interventions and research designs, and by

  17. Brazilian scientific literature on alcohol and other drugs: a bibliometric study

    Directory of Open Access Journals (Sweden)

    Gustavo Luis Caribé Cerqueira

    2016-03-01

    Full Text Available It is a bibliometric study that aimed to quantify and describe the characteristics of scientific literature on alcohol and other drugs in Brazilian universities from 2003 to 2012. The study involved the pursuit of doctoral dissertation abstracts and master's theses deposited in the Bank CAPES theses. By applying mathematical and statistical methods on literature sources were analyzed a total of 350 abstracts of theses and dissertations of 739 abstracts. All references found were systematized in software spreadsheet Statiscal Package Social Science (SPSS version 15.0 according to the following variables: type of study (Masters or PhD, publication year, area of expertise, geographic region and educational institution higher. This study showed that most of the scientific literature on the topic of alcohol and other drugs developed in the investigated period occurred in the dissertations format, with the highest concentration of studies in the Southeast, traditional focal point of scientific research in various fields. Further investigations are important to deepen the analysis of academic productions collected in addition to the summaries, contributing to a more detailed verification of the research profile, dissertation and thesis character, developed in the country

  18. Dental movement acceleration: Literature review by an alternative scientific evidence method

    Science.gov (United States)

    Camacho, Angela Domínguez; Cujar, Sergio Andres Velásquez

    2014-01-01

    The aim of this study was to analyze the majority of publications using effective methods to speed up orthodontic treatment and determine which publications carry high evidence-based value. The literature published in Pubmed from 1984 to 2013 was reviewed, in addition to well-known reports that were not classified under this database. To facilitate evidence-based decision making, guidelines such as the Consolidation Standards of Reporting Trials, Preferred Reporting items for systematic Reviews and Meta-analyses, and Transparent Reporting of Evaluations with Non-randomized Designs check list were used. The studies were initially divided into three groups: local application of cell mediators, physical stimuli, and techniques that took advantage of the regional acceleration phenomena. The articles were classified according to their level of evidence using an alternative method for orthodontic scientific article classification. 1a: Systematic Reviews (SR) of randomized clinical trials (RCTs), 1b: Individual RCT, 2a: SR of cohort studies, 2b: Individual cohort study, controlled clinical trials and low quality RCT, 3a: SR of case-control studies, 3b: Individual case-control study, low quality cohort study and short time following split mouth designs. 4: Case-series, low quality case-control study and non-systematic review, and 5: Expert opinion. The highest level of evidence for each group was: (1) local application of cell mediators: the highest level of evidence corresponds to a 3B level in Prostaglandins and Vitamin D; (2) physical stimuli: vibratory forces and low level laser irradiation have evidence level 2b, Electrical current is classified as 3b evidence-based level, Pulsed Electromagnetic Field is placed on the 4th level on the evidence scale; and (3) regional acceleration phenomena related techniques: for corticotomy the majority of the reports belong to level 4. Piezocision, dentoalveolar distraction, alveocentesis, monocortical tooth dislocation and ligament

  19. Current Scientific Evidence for a Polarized Cardiovascular Endurance Training Model.

    Science.gov (United States)

    Hydren, Jay R; Cohen, Bruce S

    2015-12-01

    Recent publications have provided new scientific evidence for a modern aerobic or cardiovascular endurance exercise prescription that optimizes the periodization cycle and maximizes potential endurance performance gains in highly trained individuals. The traditional threshold, high volume, and high-intensity training models have displayed limited improvement in actual race pace in (highly) trained individuals while frequently resulting in overreaching or overtraining (physical injury and psychological burnout). A review of evidence for replacing these models with the proven polarized training model seems warranted. This review provides a short history of the training models, summarizes 5 key studies, and provides example training programs for both the pre- and in-season periods. A polarized training program is characterized by an undulating nonlinear periodization model with nearly all the training time spent at a "light" (≤13) and "very hard" (≥17) pace with very limited time at "hard" (14-16) or race pace (6-20 Rating of Perceived Exertion [RPE] scale). To accomplish this, the polarization training model has specific high-intensity workouts separated by one or more long slow distance workouts, with the exercise intensity remaining below ventilatory threshold (VT) 1 and/or blood lactate of less than 2 mM (A.K.A. below race pace). Effect sizes for increasing aerobic endurance performance for the polarized training model are consistently superior to that of the threshold training model. Performing a polarized training program may be best accomplished by: going easy on long slow distance workouts, avoiding "race pace" and getting after it during interval workouts.

  20. A Review of Literature Regarding Scientific Controversies Surrounding the Psychometric Properties of the Rorschach Inkblot Test

    Science.gov (United States)

    Park, Kevin Neil

    2009-01-01

    The Rorschach Inkblot Test has been the focus of intense controversy, significantly impacting clinicians who currently rely on Exner's Comprehensive System (CS; Exner, 2003) in clinical and forensic settings. This paper evaluates recent empirical CS research to determine whether or not it reveals lack of scientific merit as some skeptics have…

  1. Scientific Literature on the Reliability and Validity of the Manchester Triage System (MTS Protocol: A Integrative Literature Review

    Directory of Open Access Journals (Sweden)

    Cristiane Chaves de Souza

    2015-02-01

    Full Text Available OBJECTIVE To analyze the scientific production about the validity and reliability of the Manchester Triage System (MTS protocol. METHOD A descriptive study of an integrative literature review. Articles on the validity and reliability of the MTS developed with children and adults published between 1999 and 2013 were included. RESULTS 14 articles were selected from a total of 8438, nine of validity and five of reliability. The reliability of the MTS ranged from moderate to almost perfect, with higher intra-evaluation. Regarding validity, the results seem to point to equivalent and satisfactory sensibility and specificity levels of the MTS. The instrument proved to be a good predictor of the need for hospitalization and of hospital mortality. CONCLUSION The reliability and validity of the MTS obtained in the studies is varied. It is recommended that new studies indicate necessary modifications to the MTS so that it is more safely used by nurses.

  2. Saturated fat and cardiovascular disease: the discrepancy between the scientific literature and dietary advice.

    Science.gov (United States)

    Hoenselaar, Robert

    2012-02-01

    Given the large social impact of dietary advice, it is important that the advice have a solid scientific basis. Evidence-based dietary advice should be built on results from all studies available, according to a given methodology. Conclusions should be a valid representation of the summarized results. The association between saturated fat intake and cardiovascular disease was examined. Results from three reports of leading U.S. and European advisory committees were compared with results as they were presented in the articles referred to. Findings were put into perspective with results not included in these reports. Different lines of evidence were included in the different reports. No overlap whatsoever was found in the articles included. Most results from the scientific literature were lacking for most different lines of evidence in all reports. All three reports included the effect of saturated fat on low-density lipoprotein cholesterol in the evidence linking saturated fat to cardiovascular disease, but the effect on high-density lipoprotein cholesterol was systematically ignored. Both U.S. reports failed to correctly describe the results from the prospective studies. Results and conclusions about saturated fat intake in relation to cardiovascular disease, from leading advisory committees, do not reflect the available scientific literature. Copyright © 2012 Elsevier Inc. All rights reserved.

  3. A global scientific literature of research on water quality indices: trends, biases and future directions

    Directory of Open Access Journals (Sweden)

    Maria Tereza Ribeiro Alves

    2014-09-01

    Full Text Available AIM: Water quality has been the subject of many recent studies, moreover, the physical, chemical and biological parameters of water are used to investigate water quality and can be combined into a single index, the Water Quality Index (WQI, for use by water resource managers and the general public. The aim of this study was to use scientometrics to evaluate how water quality has been addressed in the international scientific literature. METHOD: For the quantitative analysis of the publications on WQI, we used the search database SCOPUS (http://www.scopus.com. The search was performed using the words "QUALIT* WATER* INDEX*" in papers published in all databases (through 2011. RESULTS: We found 554 articles that dealt with the use of WQI the number of publications has increased significantly over the last 20 years. India had the most studies, with 177 articles, followed by China, Brazil and the United States. These four countries together published 57% of studies on WQI. We generated 15 linear models to explain the number of publication by study sit (country. According to the Akaike Information Criterion (AIC, the best model to explain the number of publications by country was the model that combined Sanitation and Public Supply. CONCLUSION: Finally, this paper presents the state of scientific literature on WQI and demonstrates the growing interest of the scientific community in this issue, which is certainly due to the importance of the quantity and quality of water for human supply, economics, health and the conservation of water resources.

  4. A weapon for the future: the scientific use of audiovisual media in the teaching of Literature.

    Directory of Open Access Journals (Sweden)

    Yosdany Morejón Ortega

    2013-03-01

    Full Text Available The novel teaching literature in high school students has become vital premise to achieve the formation of the new man. A man able to understand the complex realities of today's world, while enjoying the aesthetic pleasure of reading. Thus it was conceived this article, which takes as a benchmark the effectiveness of audiovisual media to fulfill academic training objectives expected for that level. These results were supported by scientific research previously presented as an option to the academic title of Master of Science in Education and whose validity, still part of the actions of this subject in computer Polytechnics. Given the breadth of the indicators analyzed, this topic can be generalized in other fields of scientific knowledge, always remembering that visual stimuli are powerful tools in motivation, concentration and abstraction of knowledge.

  5. Current Levels of Salt Knowledge: A Review of the Literature

    Directory of Open Access Journals (Sweden)

    Rani Sarmugam

    2014-12-01

    Full Text Available High salt intake increases the risk of hypertension and cardiovascular diseases. Given the role of knowledge as a determinant of food intake, this paper aims to review the current levels of salt knowledge and the association between salt knowledge and dietary salt intake and salt-related dietary practices in the general population. Twenty two studies were included in the review. In general, the studies showed consumers were able to identify the health risks associated with high salt intake. However, knowledge of recommended daily intakes, understanding of the relationships between salt and sodium and foods that contribute most salt to the diet were poor. Four of the five studies which examined the relationships between salt knowledge and salt-related dietary practices reported significant associations. Two important gaps in the current literature were identified. First, there is a need for a robustly validated tool to examine salt knowledge and its impact on salt intake. Second, a comprehensive salt knowledge assessment should include assessment of procedural, as well as declarative, knowledge.

  6. A reference ontology for digital scientific journals applied to systematic literature review processes

    Directory of Open Access Journals (Sweden)

    Fernando Benedet Ghisi

    Full Text Available This paper presents possible approaches to the use of a reference ontology for digital journals, supporting bibliographic processes in systematic literature reviews. The benefits are highlighted of using specialized services through "batch" or "on-the-fly" processing of information from different repositories, such as recognized and indexed databases and portals or specific websites. It is concluded that the use of reference ontology enables the creation of services that ensure greater interoperability between different repositories, allowing a more inclusive and accurate retrieval of information, as it standardizes the concepts related to the access points of scientific journals.

  7. Scientific literature on infectious diseases affecting livestock animals, longitudinal worldwide bibliometric analysis.

    Science.gov (United States)

    Ducrot, Christian; Gautret, Marjolaine; Pineau, Thierry; Jestin, André

    2016-03-14

    The objectives of this bibliometric analysis of the scientific literature were to describe the research subjects and the international collaborations in the field of research on infectious diseases in livestock animals including fishes and honeybees. It was based on articles published worldwide from 2006 through 2013. The source of data was the Web of Science, Core collection(®) and only papers fully written in English were considered. Queries were built that combined 130 descriptors related to animal species and 1213 descriptors related to diseases and pathogens. To refine and assess the accuracy of the extracted database, supplementary filters were applied to discard non-specific terms and neighbouring topics, and numerous tests were carried out on samples. For pathogens, annotation was done using a thematic terminology established to link each disease with its corresponding pathogen, which was in turn classified according to its family. A total of 62,754 articles were published in this field during this 8-year period. The average annual growth rate of the number of papers was 5%. This represents the reference data to which we compared the average annual growth rate of articles produced in each of the sub-categories that we defined. Thirty-seven percent of the papers were dedicated to ruminant diseases. Poultry, pigs and fishes were covered by respectively 21, 13 and 14% of the total. Thirty-seven percent of papers concerned bacteria, 33% viruses, 19% parasites, 2% prions, the remaining being multi-pathogens. Research on virology, especially on pigs and poultry, is increasing faster than the average. There also is increasing interest in monogastric species, fish and bees. The average annual growth rate for Asia was 10%, which is high compared to 3% for Europe and 2% for the Americas, indicating that Asia is currently playing a leading role in this field. There is a well established network of international collaborations. For 75% of the papers, the co

  8. Exploring access to scientific literature using content-based image retrieval

    Science.gov (United States)

    Deserno, Thomas M.; Antani, Sameer; Long, Rodney

    2007-03-01

    The number of articles published in the scientific medical literature is continuously increasing, and Web access to the journals is becoming common. Databases such as SPIE Digital Library, IEEE Xplore, indices such as PubMed, and search engines such as Google provide the user with sophisticated full-text search capabilities. However, information in images and graphs within these articles is entirely disregarded. In this paper, we quantify the potential impact of using content-based image retrieval (CBIR) to access this non-text data. Based on the Journal Citations Report (JCR), the journal Radiology was selected for this study. In 2005, 734 articles were published electronically in this journal. This included 2,587 figures, which yields a rate of 3.52 figures per article. Furthermore, 56.4% of these figures are composed of several individual panels, i.e. the figure combines different images and/or graphs. According to the Image Cross-Language Evaluation Forum (ImageCLEF), the error rate of automatic identification of medical images is about 15%. Therefore, it is expected that, by applying ImageCLEF-like techniques, already 95.5% of articles could be retrieved by means of CBIR. The challenge for CBIR in scientific literature, however, is the use of local texture properties to analyze individual image panels in composite illustrations. Using local features for content-based image representation, 8.81 images per article are available, and the predicted correctness rate may increase to 98.3%. From this study, we conclude that CBIR may have a high impact in medical literature research and suggest that additional research in this area is warranted.

  9. Knowledge gaps in scientific literature on maternal mortality: a systematic review.

    Science.gov (United States)

    Gil-González, Diana; Carrasco-Portiño, Mercedes; Ruiz, Maria Teresa

    2006-11-01

    Issues related to maternal mortality have generated a lot of empirical and theoretical information. However, despite the amount of work published on the topic, maternal mortality continues to occur at high rates and solutions to the problem are still not clear. Scientific research on maternal mortality is focused mainly on clinical factors. However, this approach may not be the most useful if we are to understand the problem of maternal mortality as a whole and appreciate the importance of economical, political and social macrostructural factors. In this paper, we report the number of scientific studies published between 2000 and 2004 about the main causes of maternal death, as identified by WHO, and compare the proportion of papers on each cause with the corresponding burden of each cause. Secondly, we systematically review the characteristics and quality of the papers on the macrostructural determinants of maternal mortality. In view of their burden, obstructed labour, unsafe abortion and haemorrhage are proportionally underrepresented in the scientific literature. In our review, most studies analysed were cross-sectional, and were carried out by developed countries without the participation of researchers in the developing countries where maternal mortality was studied. The main macrostructural factors mentioned were socioeconomic variables. Overall, there is a lack of published information about the cultural and political determinants of maternal mortality. We believe that a high-quality scientific approach must be taken in studies of maternal mortality in order to obtain robust comparative data and that study design should be improved to allow causality between macrostructural determinants and maternal mortality to be shown.

  10. A bibliometric study of scientific literature on the dietary therapies for epilepsy in Scopus.

    Science.gov (United States)

    Morandi, Gabriella; Guido, Davide; Tagliabue, Anna

    2015-07-01

    The aim of this study was to provide a descriptive overview of the impact and production of literature on dietary therapies for epilepsy and perform a citation analysis of the related research articles. We searched for 'ketogenic OR low-glycemic OR medium chain OR modified Atkins in TITLE AND epilep*' in Title/Abstract/Keyword in Scopus database. A total of 661 references were retrieved, 80% had been published after 2000s, 87% were published in English, and 39% of the publications were published in nine journals. The majority (76.3%) of research articles describe the clinical application of the dietary therapies regarding the classical ketogenic diet (80%), followed by the modified Atkins diet (11.5%), medium chain triglyceride diet (6.4%), and low glycemic index treatment (2.0%); the remaining are basic science studies on the mechanisms of action. The citation analysis revealed that the latter have the highest percentage variation in citation per publication across the years. Concerning the article cohorts, the greatest number of citations per publication was in 1998. The overview of the literature on the dietary therapy of epilepsy evidences a growing interest in the field with a striking prevalence of clinical over basic science studies. The most cited clinical studies have validated the efficacy of the dietary therapies; the few studies on the mechanisms of action received a great number of citations. Bibliometric analysis measuring the trends and the impact of the scientific literature would help researchers to a best knowledge of this specific topic.

  11. Connecting the Canon to Current Young Adult Literature

    Science.gov (United States)

    Rybakova, Katie; Roccanti, Rikki

    2016-01-01

    In this article we discuss the respective roles of young adult literature and literary texts in the secondary level English Language Arts classroom and explore the connections that can be made between popular young adult books and the traditional canon. We provide examples showing how young adult literature bestsellers such as "The Book…

  12. West Nile Virus: Using Adapted Primary Literature in Mathematical Biology to Teach Scientific and Mathematical Reasoning in High School

    Science.gov (United States)

    Norris, Stephen P.; Macnab, John S.; Wonham, Marjorie; de Vries, Gerda

    2009-01-01

    This paper promotes the use of adapted primary literature as a curriculum and instruction innovation for use in high school. Adapted primary literature is useful for promoting an understanding of scientific and mathematical reasoning and argument and for introducing modern science into the schools. We describe a prototype adapted from a published…

  13. West Nile Virus: Using Adapted Primary Literature in Mathematical Biology to Teach Scientific and Mathematical Reasoning in High School

    Science.gov (United States)

    Norris, Stephen P.; Macnab, John S.; Wonham, Marjorie; de Vries, Gerda

    2009-01-01

    This paper promotes the use of adapted primary literature as a curriculum and instruction innovation for use in high school. Adapted primary literature is useful for promoting an understanding of scientific and mathematical reasoning and argument and for introducing modern science into the schools. We describe a prototype adapted from a published…

  14. [Maternal mortality in Brazil: what has the scientific literature shown in the last 30 years?].

    Science.gov (United States)

    Morse, Marcia Lait; Fonseca, Sandra Costa; Barbosa, Mariane Doelinger; Calil, Manuele Bonatto; Eyer, Fernanda Pinella Carvalhal

    2011-04-01

    The aim of this study was to analyze maternal mortality in Brazil in the last 30 years, by means of a literature review. The authors performed an electronic search of scientific articles from 1980 to 2010 in LILACS and MEDLINE and found 486 abstracts, of which 50 articles were selected. Studies showed a decrease in the maternal mortality ratio (MMR), although varying across regions of the country. A few articles evaluated maternal mortality factors, identifying social inequalities associated with skin color and schooling. There was persistent underreporting of maternal deaths and inadequate completion of death certificates. Direct obstetric causes were the most frequent, mainly hypertensive diseases of pregnancy. Analysis of avoidability revealed deficiencies in prenatal and childbirth care. Despite the relevance of maternal mortality in Brazil, there are few studies on the subject. Although MMR has decreased, it is still above the desired levels. Improvements are thus needed in the quality of prenatal and perinatal care.

  15. Good practices for a literature survey are not followed by authors while preparing scientific manuscripts

    CERN Document Server

    Amancio, D R; Oliveira, O N; Costa, L da F

    2010-01-01

    The number of citations received by authors in scientific journals has become a major parameter to assess individual researchers and the journals themselves through the impact factor. A fair assessment therefore requires that the criteria for selecting references in a given manuscript should be unbiased with respect to the authors or the journals cited. In this paper, we advocate that authors should follow two mandatory principles to select papers (later reflected in the list of references) while studying the literature for a given research: i) consider similarity of content with the topics investigated, lest very related work should be reproduced or ignored; ii) perform a systematic search over the network of citations including seminal or very related papers. We use formalisms of complex networks for two datasets of papers from the arXiv repository to show that neither of these two criteria is fulfilled in practice.

  16. Falls from Height in the Construction Industry: A Critical Review of the Scientific Literature.

    Science.gov (United States)

    Nadhim, Evan A; Hon, Carol; Xia, Bo; Stewart, Ian; Fang, Dongping

    2016-06-28

    Globally, falls from height (FFH) are a substantial public health jeopardy and are among the important leading causes of serious and fatal injuries for construction workers. A comprehensive understanding of the causal factors in FFH incidents is urgently required; however, the literature appears to lack a scientific review of FFH. In this study, 297 articles that contribute to the topic of fall incidents were reviewed. Seventy-five (75) articles met the criteria for relevance and were aggregated in a database to support a critical review. A synthesis of macro-variables approach was adopted rather than a structured meta-analysis. Such a method of analysis provides the flexibility to combine previous studies' findings. The most common factors associated with FFH are risky activities, individual characteristics, site conditions, organizational characteristics, agents (scaffolds/ladders) and weather conditions. The outcomes contributed to identifying the most significant research area for safety enhancement by improving engineering facilities, behaviour investigations and FFH prevention methods.

  17. Public acceptance of wind farm development: Developer practices and review of scientific literature

    DEFF Research Database (Denmark)

    Cronin, Tom; Ram, Bonnie; Gannon, Jim

    This report is the first deliverable of Work Package 3 of the Wind2050 project. The Wind2050 project is about the public perception of wind power in Denmark, its role in the planning and development of wind farms and, ultimately, the meaning it has for reaching the Danish government’s targets...... for wind power in 2050. Work Package 3 looks specifically at how private developers handle the public’s perception of wind power and what it means for their projects. This report firstly outlines the common stages found in wind farm development and then discusses what manner of interaction the developer...... commonly has with the public at each stage. The report then shifts focus to what scientific literature says about two important topics in this realm: public risk perception and the NIMBY concept. Finally, the report concludes with suggested topics for research questions and highlights the next steps...

  18. Historical and cultural aspects of the pineal gland: comparison between the theories provided by Spiritism in the 1940s and the current scientific evidence.

    Science.gov (United States)

    Lucchetti, Giancarlo; Daher, Jorge C; Iandoli, Decio; Gonçalves, Juliane P B; Lucchetti, Alessandra L G

    2013-01-01

    Significance has been attached to the pineal gland in numerous different cultures and beliefs. One religion that has advanced the role of the pineal gland is Spiritism. The objective of the present study was to compile information on the pineal gland drawing on the books of Francisco Cândido Xavier written through psychography and to carry out a critical analysis of their scientific bases by comparing against evidence in the current scientific literature. A systematic search using the terms "pineal gland" and "epiphysis" was conducted of 12 works allegedly dictated by the spirit "André Luiz". All information on the pineal having potential correlation with the field of medicine and current studies was included. Specialists in the area were recruited to compile the information and draw parallels with the scientific literature. The themes related to the pineal gland were: mental health, reproductive function, endocrinology, relationship with physical activity, spiritual connection, criticism of the theory that the organ exerts no function, and description of a hormone secreted by the gland (reference alluding to melatonin, isolated 13 years later). The historical background for each theme was outlined, together with the theories present in the Spiritist books and in the relevant scientific literature. The present article provides an analysis of the knowledge the scientific community can acquire from the history of humanity and from science itself. The process of formulating hypotheses and scientific theories can benefit by drawing on the cultural aspects of civilization, taking into account so-called non-traditional reports and theories.

  19. Current perspectives on post systems: a literature review.

    Science.gov (United States)

    Goracci, C; Ferrari, M

    2011-06-01

    This literature review summarizes the most recent and reliable evidence on post systems. A search was limited to review articles published over the last 10 years in dental journals with an impact factor. Papers cited in the initially retrieved review articles were also included if significant. Preservation of tooth tissue, presence of a ferrule effect, and adhesion are regarded as the most effective conditions for long-term success of post-endodontic restorations. Adhesively luted fibre-reinforced composite post restorations have demonstrated satisfactory survival rates over relatively long follow-up periods. The clinical effectiveness of such restorations has been mainly ascribed to the more biomimetic behaviour of fibre-reinforced composite posts that reduces the risk of vertical root fractures. The most common type of failure when using fibre posts is post debonding and it is generally agreed that achieving stable adhesion to intraradicular dentine is more challenging than to coronal dentine. Several factors related to endodontic treatment, root canal shape, post space preparation, post translucency, adhesive cement handling and curing may have an influence on the outcome of the luting procedure. The most reliable results in fibre post cementation are obtained by etch-and-rinse adhesives in combination with dual-cure resin cements. The use of self-adhesive resin cements has also been proposed. Simplification is an obvious advantage of these new materials. However, the durability of their bond still needs to be verified with long-term clinical studies. Several techniques for pre-treating the fibre-reinforced composite post surface have been tested with the aim of improving the bond strength at the post-core and post-cement interfaces. Silicoating followed by silanization currently appears to be the most effective and convenient method for this purpose. In conclusion, the available evidence validates the use of fibre posts as an alternative to metal posts and

  20. Vinyl chloride industry in the courtroom and corporate influences on the scientific literature.

    Science.gov (United States)

    Fedeli, Ugo; Mastroangelo, Giuseppe

    2011-06-01

    Pressure from the vinyl chloride (VC) industry on researchers involved in industry-sponsored studies and on regulatory agencies has been documented since 1970s. This commentary describes the influence of a lawsuit pursued by workers of an Italian VC plant on the recent scientific debate on VC exposure and risk of hepatocellular carcinoma (HCC). Original studies carried out by consultants of the public prosecutors and by independent researchers supported the above association. VC-industry consultants published two reviews during the lawsuit, claiming that liver angiosarcoma was the only VC-related cancer. The judges concluded that the evidence of the association between HCC and VC was still not convincing. After the trial, the risk of HCC was confirmed by a re-assessment of VC carcinogenicity from the International Agency for Research on Cancer, but other subsequent industry-funded reviews criticized the new evidence. Industry-funded authors cited each other, and rarely disclosed conflicts of interest. Based on a network of collaborating researchers, industrial interests can shape the literature enhancing the background noise surrounding the scientific evidence.

  1. Applying a text mining framework to the extraction of numerical parameters from scientific literature in the biotechnology domain

    Directory of Open Access Journals (Sweden)

    André SANTOS

    2012-07-01

    Full Text Available Scientific publications are the main vehicle to disseminate information in the field of biotechnology for wastewater treatment. Indeed, the new research paradigms and the application of high-throughput technologies have increased the rate of publication considerably. The problem is that manual curation becomes harder, prone-to-errors and time-consuming, leading to a probable loss of information and inefficient knowledge acquisition. As a result, research outputs are hardly reaching engineers, hampering the calibration of mathematical models used to optimize the stability and performance of biotechnological systems. In this context, we have developed a data curation workflow, based on text mining techniques, to extract numerical parameters from scientific literature, and applied it to the biotechnology domain. A workflow was built to process wastewater-related articles with the main goal of identifying physico-chemical parameters mentioned in the text. This work describes the implementation of the workflow, identifies achievements and current limitations in the overall process, and presents the results obtained for a corpus of 50 full-text documents.

  2. Applying a text mining framework to the extraction of numerical parameters from scientific literature in the biotechnology domain

    Directory of Open Access Journals (Sweden)

    Anália LOURENÇO

    2013-07-01

    Full Text Available Scientific publications are the main vehicle to disseminate information in the field of biotechnology for wastewater treatment. Indeed, the new research paradigms and the application of high-throughput technologies have increased the rate of publication considerably. The problem is that manual curation becomes harder, prone-to-errors and time-consuming, leading to a probable loss of information and inefficient knowledge acquisition. As a result, research outputs are hardly reaching engineers, hampering the calibration of mathematical models used to optimize the stability and performance of biotechnological systems. In this context, we have developed a data curation workflow, based on text mining techniques, to extract numerical parameters from scientific literature, and applied it to the biotechnology domain. A workflow was built to process wastewater-related articles with the main goal of identifying physico-chemical parameters mentioned in the text. This work describes the implementation of the workflow, identifies achievements and current limitations in the overall process, and presents the results obtained for a corpus of 50 full-text documents.

  3. The scientific literature on Limnoperna fortunei (Dunker 1857) from 1982 to 2012.

    Science.gov (United States)

    Barbosa, Fabiana G

    2014-09-01

    Limnoperna fortunei (golden mussel) is a freshwater bivalve native to Southeast Asia, but is becoming an invasive species in several aquatic ecosystems in the world. In this study, a scientometric analysis was performed to identify the patterns, trends and gaps of knowledge for this invasive species. A survey of the published literature was conducted using the database of the Thomson Institute for Scientific Information (ISI). A total of 107 papers were surveyed that were published between 1982 and 2012 in 60 journals. The number of papers on L. fortunei over the years has increased, especially within the last eight years of the study period. Argentina, Brazil, and Japan are the countries that contributed the most papers to the literature on invasive bivalve. The majority of papers were field-observational studies. Among some important gaps that need to be addressed are the relatively small number and/or lack of studies conducted in the native countries and in countries invaded by L. fortunei, the lack of internationally collaborative publications in these countries, as well as a low number of internationally collaborative studies.

  4. Risk factors and control of hospital acquired infections: a comparison between Wikipedia and scientific literature

    Directory of Open Access Journals (Sweden)

    Elisa Maggi

    2013-03-01

    Full Text Available Background: nowadays Wikipedia is one of the main on-line sources of general information. It contains several items about nosocomial infections and their prevention, together of items on virtually every scientific topic.This study aims to assess whether Wikipedia can be considered a reliable source for professional updating, concerning Healthcare-associated Infections (HAI.Methods: Wikipedia has been searched in order to gather items on HAI. 387 items were found with a search string. The field of research was reduced at those articles (27 items containing exhaustive information in relation to prevention of HAI. The messages contained in those articles were than compared with the recommendations of a selected guideline (NICE 2003, completed by a literature search, with the aim of testing their reliability and exhaustivity.Results: 15 Wiki items were found and 51 messages selected. NICE guidelines contained 119 recommendations and 52 more recommendations has been found in a further literature search. 45.1% of Wikipedia’s messages were even found in the guidelines. On this percentage, 21.6% completely agreed with the messages of the guidelines, 15.7% partially agreed, 3.9% disagreed and 3.9% showed different level of evidence in different articles. Moreover, 54.9% of Wikipedia’s messages were not included in the guidelines and 84.2% of the recommendations contained in the guidelines were not present in Wikipedia.Conclusions: Wikipedia should not be considered as a reliable source for professional updating on HAI.

  5. Current treatment of oral candidiasis: a literature review

    OpenAIRE

    Garcia Cuesta, Carla; Sarrión Pérez, María Gracia; Bagán Sebastián, José Vicente

    2014-01-01

    Candidiasis or oral candidosis is one of the most common human opportunistic fungal infections of the oral cavity. This pathology has a wide variety of treatment which has been studied until these days. The present study offers a literature review on the treatment of oral candidiasis, with the purpose of establish which treatment is the most suitable in each case. Searching the 24 latest articles about treatment of candidiasis it concluded that the incidence depends on the type of the candidi...

  6. Current treatment of oral candidiasis: A literature review

    OpenAIRE

    Garcia Cuesta, Carla; Sarrión Pérez, María Gracia; Bagán Sebastián, José Vicente

    2014-01-01

    Candidiasis or oral candidosis is one of the most common human opportunistic fungal infections of the oral cavity. This pathology has a wide variety of treatment which has been studied until these days. The present study offers a literature review on the treatment of oral candidiasis, with the purpose of establish which treatment is the most suitable in each case. Searching the 24 latest articles about treatment of candidiasis it concluded that the incidence depends on the type of the candidi...

  7. Harnessing the wealth of Chinese scientific literature: schistosomiasis research and control in China

    Directory of Open Access Journals (Sweden)

    Mak Tippi K

    2008-09-01

    Full Text Available Abstract The economy of China continues to boom and so have its biomedical research and related publishing activities. Several so-called neglected tropical diseases that are most common in the developing world are still rampant or even emerging in some parts of China. The purpose of this article is to document the significant research potential from the Chinese biomedical bibliographic databases. The research contributions from China in the epidemiology and control of schistosomiasis provide an excellent illustration. We searched two widely used databases, namely China National Knowledge Infrastructure (CNKI and VIP Information (VIP. Employing the keyword "Schistosoma" ( and covering the period 1990–2006, we obtained 10,244 hits in the CNKI database and 5,975 in VIP. We examined 10 Chinese biomedical journals that published the highest number of original research articles on schistosomiasis for issues including languages and open access. Although most of the journals are published in Chinese, English abstracts are usually available. Open access to full articles was available in China Tropical Medicine in 2005/2006 and is granted by the Chinese Journal of Parasitology and Parasitic Diseases since 2003; none of the other journals examined offered open access. We reviewed (i the discovery and development of antischistosomal drugs, (ii the progress made with molluscicides and (iii environmental management for schistosomiasis control in China over the past 20 years. In conclusion, significant research is published in the Chinese literature, which is relevant for local control measures and global scientific knowledge. Open access should be encouraged and language barriers removed so the wealth of Chinese research can be more fully appreciated by the scientific community.

  8. Assessment of Student Skills for Critiquing Published Primary Scientific Literature Using a Primary Trait Analysis Scale

    Directory of Open Access Journals (Sweden)

    Manuel F. Varela

    2009-12-01

    Full Text Available Instructor evaluation of progressive student skills in the analysis of primary literature is critical for the development of these skills in young scientists. Students in a senior or graduate-level one-semester course in Immunology at a Masters-level comprehensive university were assessed for abilities (primary traits to recognize and evaluate the following elements of a scientific paper: Hypothesis and Rationale, Significance, Methods, Results, Critical Thinking and Analysis, and Conclusions. We tested the hypotheses that average recognition scores vary among elements and that scores change with time differently by trait. Recognition scores (scaled 1 to 5, and differences in scores were analyzed using analysis of variance (ANOVA, regression, and analysis of covariance (ANCOVA (n = 10 papers over 103 days. By multiple comparisons testing, we found that recognition scores statistically fell into two groups: high scores (for Hypothesis and Rationale, Significance, Methods, and Conclusions and low scores (for Results and Critical Thinking and Analysis. Recognition scores only significantly changed with time (increased for Hypothesis and Rationale and Results. ANCOVA showed that changes in recognition scores for these elements were not significantly different in slope (F1,16 = 0.254, P = 0.621 but the Results trait was significantly lower in elevation (F1,17 = 12.456, P = 0.003. Thus, students improved with similar trajectories, but starting and ending with lower Results scores. We conclude that students have greatest difficulty evaluating Results and critically evaluating scientific validity. Our findings show extant student skills, and the significant increase in some traits shows learning. This study demonstrates that students start with variable recognition skills and that student skills may be learned at differential rates. Faculty can use these findings or the primary trait analysis scoring scale to focus on specific paper elements for which

  9. Nordic interdisciplinary reviews of the scientific literature concerning the relationsiip between indoor environmental factors and health, Nordworks

    DEFF Research Database (Denmark)

    Sundell, Jan; Bornehag, C.-G.

    1999-01-01

    The relationship between indoor air environments and health is, however, a truly interdisciplinary area involving numerous disciplines. Scientific work is primarily "within disciplinary", often resulting in conclusions that would not stand in an interdisciplinary context. Results are mostly...... today, a number of interdisciplinary scientific groups have been created within the Nordic countries with the aim at reviewing the scientific literature within specific areas, and creating an interdisciplinary consensus on the present state of the art. Results from four so-called NORD-groups (NORDVOC...

  10. Health issues of female foreign domestic workers: a systematic review of the scientific and gray literature.

    Science.gov (United States)

    Malhotra, Rahul; Arambepola, Chandima; Tarun, Samiksha; de Silva, Vijitha; Kishore, Jugal; Østbye, Truls

    2013-01-01

    Although the number of female foreign domestic workers (FDWs) is increasing worldwide, little is known about their health issues. To systematically review the literature on health issues of female FDWs to ascertain the problems studied, identify limitations, and suggest future research and policy implications. A systematic database (PubMed, EBSCO Host, and Google Scholar) and bibliographic search identified the English-language scientific and gray literature published during 1990-2012 addressing health issues of female FDWs living with the family of the employer, using qualitative and/or quantitative research methods. Studies in which female FDWs constituted less than half of the participants were excluded. The health issues studied and identified were adverse work conditions and associated health problems (such as physical, verbal, and sexual abuse at the workplace, caregiving tasks associated with musculoskeletal strain, and chemical exposure associated with respiratory difficulty), mental health (psychotic, neurotic, and mood disorders), infectious diseases (most of the studies were on intestinal parasitic infections), and health knowledge/attitudes/practices (most of the studies were in context of sexual and reproductive health). Most of the studies were medical record reviews or questionnaire-based surveys utilizing convenience sampling or qualitative interviews/focus group discussions. Female FDWs face numerous health problems. Studies on representative, possibly longitudinal, samples of female FDWs focusing on specific health conditions are needed to better understand the epidemiology of such conditions. Concerted efforts through the governments of both labor-sending and host countries are required to improve the health, work conditions, and safety of this vulnerable group of women.

  11. Atmospheric Deposition: Sampling Procedures, Analytical Methods, and Main Recent Findings from the Scientific Literature

    Directory of Open Access Journals (Sweden)

    M. Amodio

    2014-01-01

    Full Text Available The atmosphere is a carrier on which some natural and anthropogenic organic and inorganic chemicals are transported, and the wet and dry deposition events are the most important processes that remove those chemicals, depositing it on soil and water. A wide variety of different collectors were tested to evaluate site-specificity, seasonality and daily variability of settleable particle concentrations. Deposition fluxes of POPs showed spatial and seasonal variations, diagnostic ratios of PAHs on deposited particles, allowed the discrimination between pyrolytic or petrogenic sources. Congener pattern analysis and bulk deposition fluxes in rural sites confirmed long-range atmospheric transport of PCDDs/Fs. More and more sophisticated and newly designed deposition samplers have being used for characterization of deposited mercury, demonstrating the importance of rain scavenging and the relatively higher magnitude of Hg deposition from Chinese anthropogenic sources. Recently biological monitors demonstrated that PAH concentrations in lichens were comparable with concentrations measured in a conventional active sampler in an outdoor environment. In this review the authors explore the methodological approaches used for the assessment of atmospheric deposition, from the analysis of the sampling methods, the analytical procedures for chemical characterization of pollutants and the main results from the scientific literature.

  12. Falls from Height in the Construction Industry: A Critical Review of the Scientific Literature

    Directory of Open Access Journals (Sweden)

    Evan A. Nadhim

    2016-06-01

    Full Text Available Globally, falls from height (FFH are a substantial public health jeopardy and are among the important leading causes of serious and fatal injuries for construction workers. A comprehensive understanding of the causal factors in FFH incidents is urgently required; however, the literature appears to lack a scientific review of FFH. In this study, 297 articles that contribute to the topic of fall incidents were reviewed. Seventy-five (75 articles met the criteria for relevance and were aggregated in a database to support a critical review. A synthesis of macro-variables approach was adopted rather than a structured meta-analysis. Such a method of analysis provides the flexibility to combine previous studies' findings. The most common factors associated with FFH are risky activities, individual characteristics, site conditions, organizational characteristics, agents (scaffolds/ladders and weather conditions. The outcomes contributed to identifying the most significant research area for safety enhancement by improving engineering facilities, behaviour investigations and FFH prevention methods.

  13. [Scientific output on transsexuality in the Spanish biomedical literature: bibliometric and content analyses (1973-2011)].

    Science.gov (United States)

    Navarro-Pérez, Patricia; Ortiz-Gómez, Teresa; Gil-García, Eugenia

    2015-01-01

    To explore the scientific output on transsexuality in the Spanish biomedical literature between 1973 and 2011, through bibliometric and content analyses. We carried out a descriptive, cross-sectional study of Spanish biomedical articles on transsexuality published between 1973 and 2011. The data sources consisted of Índice Médico Español and ISOC-Ciencias Sociales y Humanidades. Bibliometric and content analyses were performed. A total of 65 papers were analyzed. Knowledge on transsexuality in Spain began to appear in medical journals between 1973 and 1984. A decade of intense productivity began in 1996 and the number of journals publishing articles on transsexuality multiplied in the following years. Until 2006, the year with the most biomedical productivity, biomedical discourses reproduced representations of transsexuality anchored in biological determinism. From 2008-2011, professionals writing on the topic incorporated feminist theories and social perspectives in their discourses. In the last quarter of the twentieth century, the dominant medical discourse considered manifestations of transsexual people from a biologist perspective that conceives transsexuality as a configuration mismatch between sex and gender. The emergence of new identity categories and medical reflection from non-essentialist and non-normative gender perspectives has improved the clinical management of transsexuality. Copyright © 2014 SESPAS. Published by Elsevier Espana. All rights reserved.

  14. Understanding Texts with the Help of Experimentation: The Example of Cupellation in Arabic Scientific Literature.

    Science.gov (United States)

    Moureau, Sébastien; Thomas, Nicolas

    2016-05-01

    The article aims to show how experimentation can help us understand historical texts, by focusing on the specific case of cupellation in Arabic scientific literature. It also provides new information about cupellation in the Arab-Muslim Middle Ages. The article consists of translations of three of the most detailed accounts of cupellation: Hamdānī's Kitāb al-jawharatayn al-'atīqatayn (first half of the fourth/tenth century), Maslama b. Qāsim al-Qurṭubī, Rutbat al-ḥakīm (339-342/950-953), and Manṣūr b. Ba'ra, Kitāb kashf al-asrār al-'ilmiyya bi-dār al-ḍarb al-miṣriyya (615-635/1218-1238). These are accompanied by commentaries based on a series of experiments carried out in the course of archaeological research on cupellation, which are here used to shed new light on the medieval texts and resolve several problems in interpreting them.

  15. Current aspects of polycystic ovary syndrome: A literature review

    Directory of Open Access Journals (Sweden)

    VICTOR HUGO LOPES DE ANDRADE

    Full Text Available SUMMARY Polycystic ovary syndrome (PCOS is a heterogeneous endocrine disorder with variable prevalence, affecting about one in every 15 women worldwide. The diagnosis of polycystic ovary syndrome requires at least two of the following criteria: oligoovulation and/or anovulation, clinical and/or biochemical evidence of hyperandrogenism and morphology of polycystic ovaries. Women with PCOS appear to have a higher risk of developing metabolic disorders, hypertension and cardiovascular disorders. The aim of this article was to present a review of the literature by searching the databases Pubmed and Scielo, focusing on publications related to polycystic ovaries, including its pathogenesis, clinical manifestations, diagnosis and therapeutic aspects, as well as its association with cardiovascular and arterial hypertensive disorders.

  16. Common Agricultural Policy Reform and its Impact on Biodiversity and Livelihoods in Developing Countries - A review of scientific literature

    NARCIS (Netherlands)

    Schure, J.M.; Arts, B.J.M.

    2012-01-01

    This paper provides a review of scientific literature on the European Common Agricultural Policy (CAP) and its impacts on biodiversity in developing countries. The review was requested by Europe External Policy Advisors (EEPA) and Tilburg University to validate the findings of the study by Van Reise

  17. Semantic representation of scientific literature: bringing claims, contributions and named entities onto the Linked Open Data cloud

    Directory of Open Access Journals (Sweden)

    Bahar Sateli

    2015-12-01

    Full Text Available Motivation. Finding relevant scientific literature is one of the essential tasks researchers are facing on a daily basis. Digital libraries and web information retrieval techniques provide rapid access to a vast amount of scientific literature. However, no further automated support is available that would enable fine-grained access to the knowledge ‘stored’ in these documents. The emerging domain of Semantic Publishing aims at making scientific knowledge accessible to both humans and machines, by adding semantic annotations to content, such as a publication’s contributions, methods, or application domains. However, despite the promises of better knowledge access, the manual annotation of existing research literature is prohibitively expensive for wide-spread adoption. We argue that a novel combination of three distinct methods can significantly advance this vision in a fully-automated way: (i Natural Language Processing (NLP for Rhetorical Entity (RE detection; (ii Named Entity (NE recognition based on the Linked Open Data (LOD cloud; and (iii automatic knowledge base construction for both NEs and REs using semantic web ontologies that interconnect entities in documents with the machine-readable LOD cloud.Results. We present a complete workflow to transform scientific literature into a semantic knowledge base, based on the W3C standards RDF and RDFS. A text mining pipeline, implemented based on the GATE framework, automatically extracts rhetorical entities of type Claims and Contributions from full-text scientific literature. These REs are further enriched with named entities, represented as URIs to the linked open data cloud, by integrating the DBpedia Spotlight tool into our workflow. Text mining results are stored in a knowledge base through a flexible export process that provides for a dynamic mapping of semantic annotations to LOD vocabularies through rules stored in the knowledge base. We created a gold standard corpus from computer

  18. Identifying scientific artefacts in biomedical literature: the Evidence Based Medicine use case.

    Science.gov (United States)

    Hassanzadeh, Hamed; Groza, Tudor; Hunter, Jane

    2014-06-01

    Evidence Based Medicine (EBM) provides a framework that makes use of the current best evidence in the domain to support clinicians in the decision making process. In most cases, the underlying foundational knowledge is captured in scientific publications that detail specific clinical studies or randomised controlled trials. Over the course of the last two decades, research has been performed on modelling key aspects described within publications (e.g., aims, methods, results), to enable the successful realisation of the goals of EBM. A significant outcome of this research has been the PICO (Population/Problem-Intervention-Comparison-Outcome) structure, and its refined version PIBOSO (Population-Intervention-Background-Outcome-Study Design-Other), both of which provide a formalisation of these scientific artefacts. Subsequently, using these schemes, diverse automatic extraction techniques have been proposed to streamline the knowledge discovery and exploration process in EBM. In this paper, we present a Machine Learning approach that aims to classify sentences according to the PIBOSO scheme. We use a discriminative set of features that do not rely on any external resources to achieve results comparable to the state of the art. A corpus of 1000 structured and unstructured abstracts - i.e., the NICTA-PIBOSO corpus - is used for training and testing. Our best CRF classifier achieves a micro-average F-score of 90.74% and 87.21%, respectively, over structured and unstructured abstracts, which represents an increase of 25.48 percentage points and 26.6 percentage points in F-score when compared to the best existing approaches.

  19. Current treatment of oral candidiasis: A literature review.

    Science.gov (United States)

    Garcia-Cuesta, Carla; Sarrion-Pérez, Maria-Gracia; Bagán, Jose V

    2014-12-01

    Candidiasis or oral candidosis is one of the most common human opportunistic fungal infections of the oral cavity. This pathology has a wide variety of treatment which has been studied until these days. The present study offers a literature review on the treatment of oral candidiasis, with the purpose of establish which treatment is the most suitable in each case. Searching the 24 latest articles about treatment of candidiasis it concluded that the incidence depends on the type of the candidiasis and the virulence of the infection. Although nystatin and amphotericin b were the most drugs used locally, fluconazole oral suspension is proving to be a very effective drug in the treatment of oral candidiasis. Fluconazole was found to be the drug of choice as a systemic treatment of oral candidiasis. Due to its good antifungal properties, its high acceptance of the patient and its efficacy compared with other antifungal drugs. But this drug is not always effective, so we need to evaluate and distinguish others like itraconazole or ketoconazole, in that cases when Candida strains resist to fluconazole. Key words:Candidiasis, treatment, miconazole, fluconazole, nystatin.

  20. The History of Liquid Ear Acupuncture and the Current Scientific State of the Art.

    Science.gov (United States)

    Litscher, Daniela; Litscher, Gerhard

    2016-06-01

    This short review article presents a current overview of existing publications and scientific results regarding liquid (ear) acupuncture. The injection of liquids into defined acupuncture points of the ear is not a method commonly used in the Western world. The term liquid acupuncture has different definitions, which makes understanding each definition and differentiating one from the other difficult. General terms like pharmacopuncture, homeosiniatry, and liquid acupuncture, which all describe the method of injecting different kinds of drugs into a defined body acupuncture point, are used. This article presents the history of liquid acupuncture, as well as the current scientific state of the art, from the point of view of two European researchers. Some articles are discussed and a few practical examples are presented.

  1. [Central blockades in Pediatrics: A review of current literature].

    Science.gov (United States)

    Eizaga Rebollar, R; García Palacios, M V; Morales Guerrero, J; Torres Morera, L M

    2016-02-01

    Pediatric neuraxial anesthesia is an effective tool that can be used as a supplement or alternative to general anesthesia. However, there have always been doubts about its usefulness and risk-benefit ratio. The purpose of this review is to describe the current role of central blockades in pediatric patients, upgrade practical and safety aspects, and review the latest technological advances applied to this procedure. Copyright © 2014 Sociedad Española de Anestesiología, Reanimación y Terapéutica del Dolor. Publicado por Elsevier España, S.L.U. All rights reserved.

  2. [Gestational diabetes in the light of current literature].

    Science.gov (United States)

    Hawryluk, Jarosław; Grafka, Agnieszka; Gęca, Tomasz; Łopucki, Maciej

    2015-06-01

    This paper presents current data on the pathophysiology of gestational diabetes mellitus, classification and new diagnostic methods. Gestational Diabetes Mellitus (GDM) is defined as carbohydrate intolerance first detected during pregnancy. It is the most common metabolic disorder of pregnant women. The frequency of its occurrence depends on inter alia body weight, belonging to a particular ethnic group and diagnostic methods. GDM reveals usually between 24 and 28 weeks of gestation. The development of diabetes in pregnancy poses a threat to both the mother and the fetus. It is associated with an increased incidence of birth defects in newborns, impaired intrauterine fetal growth, higher incidence of premature births and greater percentage of the intrauterine fetus death. Amongst women complicated by gestational diabetes arterial hypertension more often unfolds. In the development of gestational diabetes mellitus important role apart from maternal and fetal hyperinsulinemia play: antagonistic to insulin placental hormones, TNFα, placental pro-inflammatory cytokines, resistin, leptin ghrelin.

  3. Rape in Armed Conflicts in the Democratic Republic of Congo: A Systematic Review of the Scientific Literature.

    Science.gov (United States)

    Kabengele Mpinga, Emmanuel; Koya, Mapendo; Hasselgard-Rowe, Jennifer; Jeannot, Emilien; Rehani, Sylvie B; Chastonay, Philippe

    2016-05-19

    We conducted a systematic review of the scientific literature between 1996 and 2013 on rape in war-ridden Eastern Democratic Republic of Congo (DRC) in order to better understand the interest of the scientific community in describing the magnitude and characteristics of the problem. The literature search was conducted in French and English using several databases (Pubmed, PsycInfo, Sapphire, BDSP, Embase, Rero, and Web of Science) with the key words "rape and DRC" combined with several Medical Subject Headings concepts. Our systematic review yielded 2,087 references, among which only 27 are original studies, that is 20 are based on population surveys and the remaining 7 are original data based on case studies and reviews. Ten studies provided prevalence rates of rape victims, 18 provided specific information on the profile of the victims, 10 reported that most of the perpetrators of rape were military personnel, 14 referred to the negligence of the government in protecting victims, and 10 reported a lack of competent health-care facilities. The awareness of rape in conflict-ridden DRC is still limited as reported in the scientific literature: Published scientific papers are scarce. Yet more research would probably help mobilize local authorities and the international community against this basic human rights violation.

  4. Summary of the scientific literature for pain and anxiety control in dentistry journal literature, January 1986-December 1987.

    Science.gov (United States)

    Hassett, L C

    1988-01-01

    This bibliography contains both foreign (in brackets) and English language citations obtained from Index to Dental Literature, Index Medicus, and Psychological Abstracts for the period January 1986 to December 1987. Although a careful search of these indexes was performed, every relevant citation may not be included. Comments or suggestions regarding this bibliography are welcomed by the author.

  5. Current systemic treatment of hepatocellular carcinoma: Areview of the literature

    Institute of Scientific and Technical Information of China (English)

    2015-01-01

    Hepatocellular carcinoma (HCC) is the fifth mostcommon form of human cancer worldwide and the thirdmost common cause of cancer-related deaths. Thestrategies of various treatments for HCC depend onthe stage of tumor, the status of patient's performanceand the reserved hepatic function. The Barcelona ClinicLiver Cancer (BCLC) staging system is currently usedmost for patients with HCC. For example, for patientswith BCLC stage 0 (very early stage) and stage A (earlystage) HCC, the curable treatment modalities, includingresection, transplantation and radiofrequency ablation,are taken into consideration. If the patients are in BCLCstage B (intermediate stage) and stage C (advancedstage) HCC, they may need the palliative transarterialchemoembolization and even the target medicationof sorafenib. In addition, symptomatic treatment isalways recommended for patients with BCLC stage D(end stage) HCC. In this review, we will attempt tosummarize the historical perspective and the currentdevelopments of systemic therapies in BCLC stage Band C in HCC.

  6. Craniocerebral Gunshot Injuries; A Review of the Current Literature

    Directory of Open Access Journals (Sweden)

    Hernando Raphael Alvis-Mirand

    2016-04-01

    Full Text Available Craniocerebral gunshot injuries (CGI are increasingly encountered by neurosurgeons in civilian and urban settings. Unfortunately, more prevalent condition in developing countries, with major armed conflicts which is still persisting, since the main trigger is violence at the national or state level. Management goals of CGI should focus on aggressive resuscitation and correction of coagulopathy; those with stable vital signs should undergo CT scan head at the earliest possible opportunity. Neuroimaging is vital for planning of surgical management, especially to determine the type of surgery, routes of the approach to the surgical target area and extraction of the impacted foreign bodies, however, surgical management is not always indicated. Although subset of such cases may be managed even with non-surgical management. The treatment comprises of immediate life salvaging resuscitative measures including control of the persistent bleeding, care of associated injury, management of raised intracranial pressure, prevention of cerebrospinal fistula formation by primary watertight dural repair and prevention of infection, through extensive debridement of contaminated, macerated or ischemic tissues; preservation of nervous tissue and restoration of anatomic structures through the hermetic sealing of dural and scalp defect. Recently, only few studies of craniocerebral penetrating injuries are published that too involving smaller patients sample sizes; although classic studies in the military and civil situation noticed associated relatively very high mortality and morbidity and psychological as well as economic impact on the affected individual, the family and the health system in providing ongoing care to the sufferers and society at large. Currently various measures are advocated with aim to reduce the incidence of CGI especially in civilian populations. It is highly necessary and immensely urgent to promote research in a neurocritical care of CGI to

  7. A new method of CCD dark current correction via extracting the dark information from scientific images

    CERN Document Server

    Ma, Bin; Hu, Yi; Liu, Qiang; Wang, Lifan; Wei, Peng

    2014-01-01

    We have developed a new method to correct dark current at relatively high temperatures for Charge-Coupled Device (CCD) images when dark frames cannot be obtained on the telescope. For images taken with the Antarctic Survey Telescopes (AST3) in 2012, due to the low cooling efficiency, the median CCD temperature was -46$^\\circ$C, resulting in a high dark current level of about 3$e^-$/pix/sec, even comparable to the sky brightness (10$e^-$/pix/sec). If not corrected, the nonuniformity of the dark current could even overweight the photon noise of the sky background. However, dark frames could not be obtained during the observing season because the camera was operated in frame-transfer mode without a shutter, and the telescope was unattended in winter. Here we present an alternative, but simple and effective method to derive the dark current frame from the scientific images. Then we can scale this dark frame to the temperature at which the scientific images were taken, and apply the dark frame corrections to the s...

  8. Resource Disambiguator for the Web: Extracting Biomedical Resources and Their Citations from the Scientific Literature

    Science.gov (United States)

    Ozyurt, Ibrahim Burak; Grethe, Jeffrey S.; Martone, Maryann E.; Bandrowski, Anita E.

    2016-01-01

    The NIF Registry developed and maintained by the Neuroscience Information Framework is a cooperative project aimed at cataloging research resources, e.g., software tools, databases and tissue banks, funded largely by governments and available as tools to research scientists. Although originally conceived for neuroscience, the NIF Registry has over the years broadened in the scope to include research resources of general relevance to biomedical research. The current number of research resources listed by the Registry numbers over 13K. The broadening in scope to biomedical science led us to re-christen the NIF Registry platform as SciCrunch. The NIF/SciCrunch Registry has been cataloging the resource landscape since 2006; as such, it serves as a valuable dataset for tracking the breadth, fate and utilization of these resources. Our experience shows research resources like databases are dynamic objects, that can change location and scope over time. Although each record is entered manually and human-curated, the current size of the registry requires tools that can aid in curation efforts to keep content up to date, including when and where such resources are used. To address this challenge, we have developed an open source tool suite, collectively termed RDW: Resource Disambiguator for the (Web). RDW is designed to help in the upkeep and curation of the registry as well as in enhancing the content of the registry by automated extraction of resource candidates from the literature. The RDW toolkit includes a URL extractor from papers, resource candidate screen, resource URL change tracker, resource content change tracker. Curators access these tools via a web based user interface. Several strategies are used to optimize these tools, including supervised and unsupervised learning algorithms as well as statistical text analysis. The complete tool suite is used to enhance and maintain the resource registry as well as track the usage of individual resources through an

  9. Resource Disambiguator for the Web: Extracting Biomedical Resources and Their Citations from the Scientific Literature.

    Science.gov (United States)

    Ozyurt, Ibrahim Burak; Grethe, Jeffrey S; Martone, Maryann E; Bandrowski, Anita E

    2016-01-01

    The NIF Registry developed and maintained by the Neuroscience Information Framework is a cooperative project aimed at cataloging research resources, e.g., software tools, databases and tissue banks, funded largely by governments and available as tools to research scientists. Although originally conceived for neuroscience, the NIF Registry has over the years broadened in the scope to include research resources of general relevance to biomedical research. The current number of research resources listed by the Registry numbers over 13K. The broadening in scope to biomedical science led us to re-christen the NIF Registry platform as SciCrunch. The NIF/SciCrunch Registry has been cataloging the resource landscape since 2006; as such, it serves as a valuable dataset for tracking the breadth, fate and utilization of these resources. Our experience shows research resources like databases are dynamic objects, that can change location and scope over time. Although each record is entered manually and human-curated, the current size of the registry requires tools that can aid in curation efforts to keep content up to date, including when and where such resources are used. To address this challenge, we have developed an open source tool suite, collectively termed RDW: Resource Disambiguator for the (Web). RDW is designed to help in the upkeep and curation of the registry as well as in enhancing the content of the registry by automated extraction of resource candidates from the literature. The RDW toolkit includes a URL extractor from papers, resource candidate screen, resource URL change tracker, resource content change tracker. Curators access these tools via a web based user interface. Several strategies are used to optimize these tools, including supervised and unsupervised learning algorithms as well as statistical text analysis. The complete tool suite is used to enhance and maintain the resource registry as well as track the usage of individual resources through an

  10. [Amalgam--a question of belief? A review and assessment of the current literature].

    Science.gov (United States)

    Metzler, H; Metzler, C

    1998-01-01

    Several hundred written sources have been researched regarding old and new findings. Forgotten and new facts are covered in four chapters. One of the authors is a retired industrial chemist, and the other a dental surgeon. In the first section the natural and synthetic sources of mercury are explained. In every scientific study the ubiquity of mercury for billions of years must be taken into consideration. The second chapter looks at the toxicology of mercury and its compounds. Well known catastrophies in Japan and Iraq are depicted. Individual intoxications are hardly mentioned in literature. The third chapter is devoted to the dental amalgam, a silver alloy with both physical-chemical properties, and corrosive and thermal behaviour. An attempt is made to define the mercury balance. The forth paragraph deals with the disposal and recycling of mercury. Many dental associations are currently discussing the possibility of recycling amalgam, which is rather a stable silver alloy than a volatile mercury compound. A controlled landfill disposal of dental amalgam will absorb a certain quantity of mercury during its life cycle, and is positive. Recycling is expensive, energy consuming and causes additional exposure. Unless silver and mercury become rare metals, recycling should not be considered. As yet no worldwide regulatory procedures exist.

  11. A three-phase model proposal for the evolution of scientific communication: from first print periodicals to current electronic communication system

    Directory of Open Access Journals (Sweden)

    Patrícia Bertin

    Full Text Available Scientific communication has undergone deep transformations, since the emergence of Internet. Aiming to provide further thought on the evolution of scientific communication, this paper features a historical overview of the scientific communication advances over the last twenty years through a three-phase model for the evolution of the electronic journal and the preprints services, and presents Brazilian contemporary panorama for scientific communication. The three-phase model presented in this work is an adaptation of that one proposed by Tenopir et al. (2003 to describe the patterns of journal use by scientists since 1990. The early evolutionary phase followed the emergence of the first digital journals and the creation of repositories in the Web for publishing preliminary versions of scientific literature on the author’s initiative; by that time, most academics reproved electronic publishing initiatives. From 1996 and forward, in the consolidation phase, electronic journals were commonly identical to their print counterparts; the acceptance of the electronic format began to increase, and preprint services got underway in several disciplines. The advanced evolutionary phase started with the world discussion on open access to scientific information. The comparison of the current electronic journal with that viewed by enthusiasts in the first years of the 1990s shows that some aspects still remain to be improved in electronic formal and informal communication, towards effective dissemination of scientific information.

  12. Private Science and Public Knowledge: The Committee for the Scientific Investigation of the Claims of the Paranormal and its Use of the Literature.

    Science.gov (United States)

    Pinch, T. J.; Collins, H. M.

    1984-01-01

    Shows the part played by formal/informal literatures in the social construction of scientific knowledge, analyzing the work of the "Committee for the Scientific Investigation of the Claims of the Paranormal" (which critically investigates fringe-sciences). Indicates that popular literature can deconstruct facts while scientific…

  13. Concussions: What a neurosurgeon should know about current scientific evidence and management strategies

    Science.gov (United States)

    Neal, Matthew T.; Wilson, Jonathan L.; Hsu, Wesley; Powers, Alexander K.

    2012-01-01

    Background: There has been a tremendous amount of interest focused on the topic of concussions over the past few decades. Neurosurgeons are frequently consulted to manage patients with mild traumatic brain injuries (mTBI) that have radiographic evidence of cerebral injury. These injuries share significant overlap with concussions, injuries that typically do not reveal radiographic evidence of structural injury, in the realms of epidemiology, pathophysiology, outcomes, and management. Further, neurosurgeons often manage patients with extracranial injuries that have concomitant concussions. In these cases, neurosurgeons are often the only “concussion experts” that patients encounter. Results: The literature has been reviewed and data have been synthesized on the topic including sections on historical background, epidemiology, pathophysiology, diagnostic advances, clinical sequelae, and treatment suggestions, with neurosurgeons as the intended target audience. Conclusions: Neurosurgeons should have a fundamental knowledge of the scientific evidence that has developed regarding concussions and be prepared to guide patients with treatment plans. PMID:22439107

  14. Using HeLa cell stress response to introduce first year students to the scientific method, laboratory techniques, primary literature, and scientific writing.

    Science.gov (United States)

    Resendes, Karen K

    2015-01-01

    Incorporating scientific literacy into inquiry driven research is one of the most effective mechanisms for developing an undergraduate student's strength in writing. Additionally, discovery-based laboratories help develop students who approach science as critical thinkers. Thus, a three-week laboratory module for an introductory cell and molecular biology course that couples inquiry-based experimental design with extensive scientific writing was designed at Westminster College to expose first year students to these concepts early in their undergraduate career. In the module students used scientific literature to design and then implement an experiment on the effect of cellular stress on protein expression in HeLa cells. In parallel the students developed a research paper in the style of the undergraduate journal BIOS to report their results. HeLa cells were used to integrate the research experience with the Westminster College "Next Chapter" first year program, in which the students explored the historical relevance of HeLa cells from a sociological perspective through reading The Immortal Life of Henrietta Lacks by Rebecca Skloot. In this report I detail the design, delivery, student learning outcomes, and assessment of this module, and while this exercise was designed for an introductory course at a small primarily undergraduate institution, suggestions for modifications at larger universities or for upper division courses are included. Finally, based on student outcomes suggestions are provided for improving the module to enhance the link between teaching students skills in experimental design and execution with developing student skills in information literacy and writing.

  15. Medical ozone is now ready for a scientific challenge: current status and future perspectives

    Directory of Open Access Journals (Sweden)

    Gregorio Martinez-Sanchez

    2012-06-01

    Full Text Available The aim of the present review is to clarify some of the basic mechanisms underlying ozone therapy. Indeed, after its empiric use started at the beginning of the last century, science is now ready to give a chance to the more and more medical doctors working in this field. Unfortunately, the lack of a full recognition by the health authorities and some ostracism against it is, up to date, the major obstacle for its full medical acceptance. Anyway, in the last years and thanks to the contributions of several scientists, most of the mechanisms characterizing the bio-humoral activity of ozone have been scientifically outlined. The built up of randomized clinical studies is going on slowly despite the lack of funds and the difficulties bound mainly to the huge variability of the ozone action. The thousand and thousand medical doctors involved in the use of ozone as emerging therapy, must be fully educated about the properties of this gas in the aim to counteract scientifically the criticisms of colleagues devoted to other field of medicine and not expert of the ozone pharmacological properties. Is for this reason that we encourage all the professionals to deeply increase the knowledge related to the scientific data produced and published on the international literatures in the field of the ozone therapy. For the future we suggest the use of ozone not in alternative but as a complement of the most appropriate pharmacological treatments also in the aim to reduce some side effects derived from a chronic drug use. The lack of a well-defined binding site for the ozone molecule could suggest the introduction of virtual receptors for the supposed biological activity of ozone acting mostly throughout second messengers pathways. [J Exp Integr Med 2012; 2(3.000: 193-196

  16. Academic Writing in Reflexive Professional Writing: Citations of Scientific Literature in Supervised Pre-Service Training Reports

    Directory of Open Access Journals (Sweden)

    Lívia Chaves de Melo

    2013-06-01

    Full Text Available In this paper we investigate citation practices of scientific literature in reflexive writing from the genre of supervised pre-service training report produced by pre-service teachers enrolled in the mandatory pre-service training subject of English Language Teaching, at an undergraduate language teaching course. The aim of this research is to analyze how these pre-services teacher represent themselves based on citation practices of scientific literature, and characterize some of the functions deployed by the citations in the reflexive writing emerging in the academic sphere. We use the dialogic approach to language from Bakhtinian studies as a theoretical base, as well as theoretical and methodological contributions regarding types of sequences and of discourse proposed by Adam and Bronckart. The results of this research show that the practice of citation of scientific literature is an invocation of authority as a form of erudition, amplification and ornamentation of the discourse produced. This practice can also guide pedagogical action developed by pre-service teachers in their supervised training.

  17. [Current state of the scientific activity of the Aachen group concerning number processing].

    Science.gov (United States)

    Rohlfs-Domínguez, P

    The research group from Willmes and colleagues is one of the most advanced research groups in cognitive neuroscience. The use and nature of the numeric magnitude representation constitutes one of the study objects of the mentioned research group. This mental representation provokes a great controversy among the members of the scientific community studying number processing and arithmetic. As a consequence, there are several different theoretical models concerning number processing. In this work, we have reviewed some of the scientific studies realized by the Aachen group concerning number processing, with the aim to expound the current state of its activity. In the works from Willmes and colleagues, we can notice a logic sequence, regarding the formulation of work hypothesis. The course of evolution of their activity starts studying number processing and arithmetic on German listener population and continues with a progressive integration of the German deaf population into their work. There is, as well, an emergent trend in this group to research number processing at the classroom. This means to examine the underlying mental representations in the education field. The information included in the studies analyzed here, leads to several scientific questions which need to be researched in future studies, and questions and complements what has been supported by other research groups.

  18. Library consortia and funding scientific literature and databases in Slovenia in the year 2010

    Directory of Open Access Journals (Sweden)

    Primož Južnič

    2010-01-01

    Full Text Available One of the basic ways of scientific communication is publishing in scientific journals which play a key role in the evaluation of scientific excellence and as such represent an indispensable part of scientific infrastructure. Their relevance is reflected in the high use rate. The article presents experiences in consortium purchases of scientific journals in the Republic of Slovenia within the management of the Central Technological Library at the University of Ljubljana (CTK. In 2009, the number of successful full-text article requests amounted to 829,576 EUR, an increase of 33% compared to the year 2008 and 178% more requests than in 2006. The Slovenian Research Agency (SRA supports libraries in consortium purchasing and is responsible for co-financing foreign scientific library resources in the Republic of Slovenia. In 2009, the amount of EUR 3,520,000 was given to libraries, of which the consortium received EUR 1,421,458,an increase of 419% compared to the previous year. Consequently eight new members joined the consortium in 2010, now involving 22 institutions. The article also presents the benefits of additional financial means given to the consortium.

  19. Green areas and health outcomes: a systematic review of the scientific literature

    Directory of Open Access Journals (Sweden)

    Francesco Di Nardo

    2010-12-01

    Full Text Available

    Background: Growing medical evidence shows that access to the natural environment improves health and wellbeing, prevents disease and helps people recover from illness. Experiencing nature in the outdoors can help tackle obesity and coronary heart disease. Green areas exert their benefits on both physical and mental health, promoting physical activity and strengthening the sense of community thus positively influencing social interaction. Urbanization poses problems through effects such as environmental pollution, accidents, heat island effects, climate change and a consequent demand for urban green areas.

    Material and methods: We performed literature searches of electronic journal databases for studies and reviews that focused on the relationship between green spaces and health. We looked at the effects on physical health, mental health, social health, physical activity and well-being in its broadest sense and then we categorically organized our findings.

    Results: We found many contradictory and unexpected results. However, the reported findings were generally consistent and supported the current view that urban design and the availability of urban green spaces are key elements of prosperity and individual/collective comfort, so as to influence both the perceived health and the objective physical conditions in a measurable way. A weak relationship between physical activity levels and green space availability is observed.

    Conclusions: The occasionally contradictory results that emerged in this study suggest that a opulation’s esponse to urban design interventions is often unpredictable. Further research is needed to quantify the trength of relation between green spaces and urban health, but also to investigate the social and behavioural spects which are more difficult to measure and understand.

  20. Concentration of the most-cited papers in the scientific literature: analysis of journal ecosystems.

    Directory of Open Access Journals (Sweden)

    John P A Ioannidis

    Full Text Available BACKGROUND: A minority of scientific journals publishes the majority of scientific papers and receives the majority of citations. The extent of concentration of the most influential articles is less well known. METHODS/PRINCIPAL FINDINGS: The 100 most-cited papers in the last decade in each of 21 scientific fields were analyzed; fields were considered as ecosystems and their "species" (journal diversity was evaluated. Only 9% of journals in Journal Citation Reports had published at least one such paper. Among this 9%, half of them had published only one such paper. The number of journals that had published a larger number of most-cited papers decreased exponentially according to a Lotka law. Except for three scientific fields, six journals accounted for 53 to 94 of the 100 most-cited papers in their field. With increasing average number of citations per paper (citation density in a scientific field, concentration of the most-cited papers in a few journals became even more prominent (p<0.001. Concentration was unrelated to the number of papers published or number of journals available in a scientific field. Multidisciplinary journals accounted for 24% of all most-cited papers, with large variability across fields. The concentration of most-cited papers in multidisciplinary journals was most prominent in fields with high citation density (correlation coefficient 0.70, p<0.001. Multidisciplinary journals had published fewer than eight of the 100 most-cited papers in eight scientific fields (none in two fields. Journals concentrating most-cited original articles often differed from those concentrating most-cited reviews. The concentration of the most-influential papers was stronger than the already prominent concentration of papers published and citations received. CONCLUSIONS: Despite a plethora of available journals, the most influential papers are extremely concentrated in few journals, especially in fields with high citation density. Existing

  1. Mindfulness-based mobile applications: literature review and analysis of current features.

    Science.gov (United States)

    Plaza, Inmaculada; Demarzo, Marcelo Marcos Piva; Herrera-Mercadal, Paola; García-Campayo, Javier

    2013-11-01

    Interest in mindfulness has increased exponentially, particularly in the fields of psychology and medicine. The trait or state of mindfulness is significantly related to several indicators of psychological health, and mindfulness-based therapies are effective at preventing and treating many chronic diseases. Interest in mobile applications for health promotion and disease self-management is also growing. Despite the explosion of interest, research on both the design and potential uses of mindfulness-based mobile applications (MBMAs) is scarce. Our main objective was to study the features and functionalities of current MBMAs and compare them to current evidence-based literature in the health and clinical setting. We searched online vendor markets, scientific journal databases, and grey literature related to MBMAs. We included mobile applications that featured a mindfulness-based component related to training or daily practice of mindfulness techniques. We excluded opinion-based articles from the literature. The literature search resulted in 11 eligible matches, two of which completely met our selection criteria-a pilot study designed to evaluate the feasibility of a MBMA to train the practice of "walking meditation," and an exploratory study of an application consisting of mood reporting scales and mindfulness-based mobile therapies. The online market search eventually analyzed 50 available MBMAs. Of these, 8% (4/50) did not work, thus we only gathered information about language, downloads, or prices. The most common operating system was Android. Of the analyzed apps, 30% (15/50) have both a free and paid version. MBMAs were devoted to daily meditation practice (27/46, 59%), mindfulness training (6/46, 13%), assessments or tests (5/46, 11%), attention focus (4/46, 9%), and mixed objectives (4/46, 9%). We found 108 different resources, of which the most used were reminders, alarms, or bells (21/108, 19.4%), statistics tools (17/108, 15.7%), audio tracks (15/108, 13

  2. Mindfulness-Based Mobile Applications: Literature Review and Analysis of Current Features

    Science.gov (United States)

    Plaza, Inmaculada; Demarzo, Marcelo Marcos Piva; Herrera-Mercadal, Paola

    2013-01-01

    Background Interest in mindfulness has increased exponentially, particularly in the fields of psychology and medicine. The trait or state of mindfulness is significantly related to several indicators of psychological health, and mindfulness-based therapies are effective at preventing and treating many chronic diseases. Interest in mobile applications for health promotion and disease self-management is also growing. Despite the explosion of interest, research on both the design and potential uses of mindfulness-based mobile applications (MBMAs) is scarce. Objective Our main objective was to study the features and functionalities of current MBMAs and compare them to current evidence-based literature in the health and clinical setting. Methods We searched online vendor markets, scientific journal databases, and grey literature related to MBMAs. We included mobile applications that featured a mindfulness-based component related to training or daily practice of mindfulness techniques. We excluded opinion-based articles from the literature. Results The literature search resulted in 11 eligible matches, two of which completely met our selection criteria–a pilot study designed to evaluate the feasibility of a MBMA to train the practice of “walking meditation,” and an exploratory study of an application consisting of mood reporting scales and mindfulness-based mobile therapies. The online market search eventually analyzed 50 available MBMAs. Of these, 8% (4/50) did not work, thus we only gathered information about language, downloads, or prices. The most common operating system was Android. Of the analyzed apps, 30% (15/50) have both a free and paid version. MBMAs were devoted to daily meditation practice (27/46, 59%), mindfulness training (6/46, 13%), assessments or tests (5/46, 11%), attention focus (4/46, 9%), and mixed objectives (4/46, 9%). We found 108 different resources, of which the most used were reminders, alarms, or bells (21/108, 19.4%), statistics tools

  3. An Evaluation of Text Mining Tools as Applied to Selected Scientific and Engineering Literature.

    Science.gov (United States)

    Trybula, Walter J.; Wyllys, Ronald E.

    2000-01-01

    Addresses an approach to the discovery of scientific knowledge through an examination of data mining and text mining techniques. Presents the results of experiments that investigated knowledge acquisition from a selected set of technical documents by domain experts. (Contains 15 references.) (Author/LRW)

  4. An annotated bibliography of scientific literature on research and management activities conducted in Coram Experimental Forest

    Science.gov (United States)

    Ilana Abrahamson; Katie Lyon

    2012-01-01

    The Coram Experimental Forest represents western larch-mixed conifer forests of the Northern Rockies. Western larch research was centered at Coram Experimental Forest (CEF) to provide a scientific basis to regenerate and grow this important and valuable species. For example, the long-term silvicultural studies installed at CEF are allowing researchers and managers to...

  5. An Evaluation of Text Mining Tools as Applied to Selected Scientific and Engineering Literature.

    Science.gov (United States)

    Trybula, Walter J.; Wyllys, Ronald E.

    2000-01-01

    Addresses an approach to the discovery of scientific knowledge through an examination of data mining and text mining techniques. Presents the results of experiments that investigated knowledge acquisition from a selected set of technical documents by domain experts. (Contains 15 references.) (Author/LRW)

  6. STATE OF THE ART OF SCIENTIFIC LITERATURE ON Hancornia speciosa: TRENDS AND GAPS

    Directory of Open Access Journals (Sweden)

    LUCIANE MADUREIRA DE ALMEIDA

    Full Text Available ABSTRACT The economic and scientific interest in Hancornia speciosa (mangabeira has been growing in recent years, mainly due to the marketing of fruit and extraction of natural compounds with high pharmacological potential. In this study, a scientometric survey about mangabeira was carried out in order to promote and direct future studies on the species. As a result, low scientific productivity associated with this species was found, with only 131 articles published in the last 69 years. In addition, this study identified some trends in bibliographic production on mangabeira, among them: the increasing number of articles over the years; scientific dissemination in nationwide journals; the main focus of this study is associated with agronomic studies; the experimental approach is more frequent and usually associated with populations of restricted geographical distribution; and the scientific production is mainly from education institutions. Furthermore, this study also allowed the identification of some gaps in knowledge about mangabeira, among them the difficulty in describing and characterizing botanical lines; lack of analysis of the genetic diversity of widely distributed populations; lack of management and conservation projects for the species; lack of description of cultivation, collection and preservation techniques of fruits; and lack of identification of natural compounds responsible for its pharmacological activity. It is expected that the data generated in this study will serve to direct future studies on H. speciosa.

  7. A review of scientific topics and literature in abdominal radiology in Germany. Pt. 2. Abdominal parenchymal organs

    Energy Technology Data Exchange (ETDEWEB)

    Grenacher, L. [Diagnostik Muenchen-Diagnostic Imaging Centre (Germany); Juchems, M.S. [Konstanz Hospital (Germany). Diagnostic and Interventional Radiology; Holzapfel, K. [Technische Univ. Muenchen (Germany). Dept. of Radiology; Kinner, S.; Lauenstein, T.C. [University Hospital Essen (Germany). Dept. of Radiology; Wessling, J. [Clemens Hospital Muenchen (Germany). Dept. of Radiology; Schreyer, A.G. [University Hospital Regenburg (Germany). Dept. of Radiology

    2016-03-15

    The working group for abdominal and gastrointestinal diagnosis is a group of the German Radiological Society (DRG) focusing clinically and scientifically on the diagnosis and treatment of the gastrointestinal tract as well as the parenchymal abdominal organs. In this article we give an up-to-date literature review of scientific radiological topics especially covered by German radiologists. The working group experts cover the most recent relevant studies concerning liver-specific contrast media with an emphasis on a new classification system for liver adenomas. Additionally studies regarding selective internal radiotherapy (SIRT) are reviewed. For the pancreas the most important tumors are described followed by an introduction to the most recently introduced functional imaging techniques. The manuscript concludes with some remarks on recent studies and concerning chronic pancreatitis as well as autoimmune pancreatitis.

  8. Soft drinks and dental health: a review of the current literature.

    Science.gov (United States)

    Tahmassebi, J F; Duggal, M S; Malik-Kotru, G; Curzon, M E J

    2006-01-01

    In recent years there has been increased interest in the role of commercial soft drinks in dental diseases namely as dental caries and erosion. The objective of this paper has been to review the past and current literature to determine the present knowledge on this subject. The literature related to dental caries, erosion, drinks, soft drinks and fruit juices was reviewed. The literature shows efforts have been taken to modify soft drinks by either adding or deleting certain components so as to reduce their harmful effects on teeth. A rational protocol to encourage the sensible use of drinks and the modification of drinks to render them less harmful would be advisable.

  9. SYMBIOmatics: Synergies in Medical Informatics and Bioinformatics - Exploring current scientific literature for emerging topics

    NARCIS (Netherlands)

    D. Rebholz-Schuhman (Dietrich); G. Cameron (Graham); D. Clark (Dominic); E.M. van Mulligen (Erik); J.-L. Coatrieux; E. del Hoyo Barbolla (Eva); F. Martin-Sanchez (Fernando); L. Milanesi (Luciano); I. Porro (Ivan); F. Beltrame (Francesco); I. Tollis (Ioannis); J. van der Lei (Johan)

    2007-01-01

    textabstractBackground: The SYMBIOmatics Specific Support Action (SSA) is "an information gathering and dissemination activity" that seeks "to identify synergies between the bioinformatics and the medical informatics" domain to improve collaborative progress between both domains (ref. to

  10. Current interpretations and scientific rationale of the ozone usage in dentistry: A systematic review of literature

    Directory of Open Access Journals (Sweden)

    Anil Kumar

    2014-01-01

    Full Text Available In the era of antibiotic resistance, a naturally occurring substance is needed to completely cure the infection without any toxic side-effects; a responsibility that "O 3 or Ozone" seems to implement sincerely. Ozone gas has a high-oxidation potential and has the capacity to stimulate blood circulation and the immune response. It is a great supplement to conventional therapeutic dental modalities. Treatment may be achieved by increasing the resistance of the tooth against the microbial activity and reducing the extent of microbial activity. In addition to the recent materials and techniques, the therapeutic actions of ozone may provide beneficial results by reducing the demineralization of the tooth. Its bactericide, virucide and fungicide effects are based on its strong oxidation effect with the formation of free radicals as well as its direct destruction of almost all microorganisms. This potentially beneficial agent has been used in dentistry also. Ozone has a wide application in dentistry which includes treatment of carious lesions, root canal disinfection, wound healing impairments after surgical interventions, plaque control, disinfection of dentures, etc., The purpose of this article is to summarize the mechanism of action and different modalities of ozone therapy in the practice of dentistry.

  11. pGenN, a gene normalization tool for plant genes and proteins in scientific literature.

    Directory of Open Access Journals (Sweden)

    Ruoyao Ding

    Full Text Available Automatically detecting gene/protein names in the literature and connecting them to databases records, also known as gene normalization, provides a means to structure the information buried in free-text literature. Gene normalization is critical for improving the coverage of annotation in the databases, and is an essential component of many text mining systems and database curation pipelines.In this manuscript, we describe a gene normalization system specifically tailored for plant species, called pGenN (pivot-based Gene Normalization. The system consists of three steps: dictionary-based gene mention detection, species assignment, and intra species normalization. We have developed new heuristics to improve each of these phases.We evaluated the performance of pGenN on an in-house expertly annotated corpus consisting of 104 plant relevant abstracts. Our system achieved an F-value of 88.9% (Precision 90.9% and Recall 87.2% on this corpus, outperforming state-of-art systems presented in BioCreative III. We have processed over 440,000 plant-related Medline abstracts using pGenN. The gene normalization results are stored in a local database for direct query from the pGenN web interface (proteininformationresource.org/pgenn/. The annotated literature corpus is also publicly available through the PIR text mining portal (proteininformationresource.org/iprolink/.

  12. Trends in Scientific Literature on Atypical Antipsychotics in South Korea: A Bibliometric Study

    Science.gov (United States)

    Shen, Winston W.; Pae, Chi-Un; Moreno, Raquel; Rubio, Gabriel; Molina, Juan D.; Noriega, Concha; Pérez-Nieto, Miguel A.; Huelves, Lorena; Álamo, Cecilio

    2013-01-01

    Objective We have carried out a bibliometric study on the scientific publications in relation to atypical or second-generation antipsychotic drugs (SGAs) in South Korea. Methods With the EMBASE and MEDLINE databases, we selected those publications made in South Korea whose title included the descriptors atypic* (atypical*) antipsychotic*, second-generation antipsychotic*, clozapine, risperidone, olanzapine, ziprasidone, quetiapine, sertindole, aripiprazole, paliperidone, amisulpride, zotepine, asenapine, iloperidone, lurasidone, perospirone and blonanserin. We applied some bibliometric indicators of paper production and dispersion with Price's law and Bradford's law, respectively. We also calculated the participation index (PI) of the different countries, and correlated the bibliometric data with some social and health data from Korea (such as total per capita expenditure on health and gross domestic expenditure on research and development). Results We collected 326 original papers published between 1993 and 2011. Our results state fulfilment of fulfilled Price's law, with scientific production on SGAs showing exponential growth (correlation coefficient r=0.8978, as against an r=0.8149 after linear adjustment). The most widely studied drugs were risperidone (91 papers), aripiprazole (77), olanzapine (53), and clozapine (43). Division into Bradford zones yielded a nucleus occupied by the Progress in Neuro-Psychopharmacology and Biological Psychiatry (36 articles). A total of 86 different journals were published, with 4 of the first 10 used journals having an impact factor being greater than 4. Conclusion The publications on SGAs in South Korea have undergone exponential growth over the studied period, without evidence of reaching a saturation point. PMID:23482954

  13. Déjà vu: a database of highly similar citations in the scientific literature

    Science.gov (United States)

    Errami, Mounir; Sun, Zhaohui; Long, Tara C.; George, Angela C.; Garner, Harold R.

    2009-01-01

    In the scientific research community, plagiarism and covert multiple publications of the same data are considered unacceptable because they undermine the public confidence in the scientific integrity. Yet, little has been done to help authors and editors to identify highly similar citations, which sometimes may represent cases of unethical duplication. For this reason, we have made available Déjà vu, a publicly available database of highly similar Medline citations identified by the text similarity search engine eTBLAST. Following manual verification, highly similar citation pairs are classified into various categories ranging from duplicates with different authors to sanctioned duplicates. Déjà vu records also contain user-provided commentary and supporting information to substantiate each document's categorization. Déjà vu and eTBLAST are available to authors, editors, reviewers, ethicists and sociologists to study, intercept, annotate and deter questionable publication practices. These tools are part of a sustained effort to enhance the quality of Medline as ‘the’ biomedical corpus. The Déjà vu database is freely accessible at http://spore.swmed.edu/dejavu. The tool eTBLAST is also freely available at http://etblast.org. PMID:18757888

  14. Deja vu: a database of highly similar citations in the scientific literature.

    Science.gov (United States)

    Errami, Mounir; Sun, Zhaohui; Long, Tara C; George, Angela C; Garner, Harold R

    2009-01-01

    In the scientific research community, plagiarism and covert multiple publications of the same data are considered unacceptable because they undermine the public confidence in the scientific integrity. Yet, little has been done to help authors and editors to identify highly similar citations, which sometimes may represent cases of unethical duplication. For this reason, we have made available Déjà vu, a publicly available database of highly similar Medline citations identified by the text similarity search engine eTBLAST. Following manual verification, highly similar citation pairs are classified into various categories ranging from duplicates with different authors to sanctioned duplicates. Déjà vu records also contain user-provided commentary and supporting information to substantiate each document's categorization. Déjà vu and eTBLAST are available to authors, editors, reviewers, ethicists and sociologists to study, intercept, annotate and deter questionable publication practices. These tools are part of a sustained effort to enhance the quality of Medline as 'the' biomedical corpus. The Déjà vu database is freely accessible at http://spore.swmed.edu/dejavu. The tool eTBLAST is also freely available at http://etblast.org.

  15. Needle-like instruments for steering through solid organs: A review of the scientific and patent literature.

    Science.gov (United States)

    Scali, Marta; Pusch, Tim P; Breedveld, Paul; Dodou, Dimitra

    2016-12-01

    High accuracy and precision in reaching target locations inside the human body is necessary for the success of percutaneous procedures, such as tissue sample removal (biopsy), brachytherapy, and localized drug delivery. Flexible steerable needles may allow the surgeon to reach targets deep inside solid organs while avoiding sensitive structures (e.g. blood vessels). This article provides a systematic classification of possible mechanical solutions for three-dimensional steering through solid organs. A scientific and patent literature search of steerable instrument designs was conducted using Scopus and Web of Science Derwent Innovations Index patent database, respectively. First, we distinguished between mechanisms in which deflection is induced by the pre-defined shape of the instrument versus mechanisms in which an actuator changes the deflection angle of the instrument on demand. Second, we distinguished between mechanisms deflecting in one versus two planes. The combination of deflection method and number of deflection planes led to eight logically derived mechanical solutions for three-dimensional steering, of which one was dismissed because it was considered meaningless. Next, we classified the instrument designs retrieved from the scientific and patent literature into the identified solutions. We found papers and patents describing instrument designs for six of the seven solutions. We did not find papers or patents describing instruments that steer in one-plane on-demand via an actuator and in a perpendicular plane with a pre-defined deflection angle via a bevel tip or a pre-curved configuration.

  16. Quantitative analysis of the scientific literature on acetaminophen in medicine and biology: a 2003-2005 study.

    Science.gov (United States)

    Robert, Claude; Saenz-Feijoo, Rosa; Gaudy, Jean-François; Arreto, Charles-Daniel

    2009-04-01

    This study quantifies the utilization of acetaminophen in life sciences and clinical medicine using bibliometric indicators. A total of 1626 documents involving acetaminophen published by 74 countries during 2003-2005 in the Thompson-Scientific Life sciences and Clinical Medicine collections were identified and analyzed. The USA leads in the number of publications followed by the UK, and industrialized countries, including France, Japan and Germany; the presence of countries such as China, India and Turkey among the top 15 countries deserves to be noticed. The European Union stands as a comparable contributor to the USA, both in terms of number of publications and in terms of profile of papers distributed among subcategories of Life Sciences and Clinical Medicine disciplines. All documents were published in 539 different journals. The most prolific journals were related to pharmacology and/or pharmaceutics. All aspects of acetaminophen (chemistry, pharmacokinetics, metabolism, etc.) were studied with primary interest for therapeutic use (42%) and adverse effects (28%) comprising a large part of publications focusing on acetaminophen hepatotoxicity. This quantitative overview provides as to the interest of the scientific community in this analgesic and completes the various review documents that regularly appear in the scientific literature.

  17. Health needs: an analysis of Brazilian scientific literature from 1990 to 2004

    Directory of Open Access Journals (Sweden)

    Célia Maria Sivalli Campos

    2007-01-01

    Full Text Available This paper assumes that the health services' responses to health needs were affected by the regulation of the Brazilian public health system. The study objective is to identify the health-service trends found in scientific publications. Among the 73 publications selected from the LILACS on-line database, 66 (90.4% did not mention the concept of health needs. Those that did had a reflective stance toward the subject. Health needs as defined in those articles were similar for all individuals, not considering them as members of a social class, a circumstance that defines health-needs characteristics. The results of this study are worrisome because health care delivery has been emphasizing sickness and reinforcing classification practices, rather than enabling emancipating praxis.

  18. Foot and ankle fractures during childhood: review of the literature and scientific evidence for appropriate treatment

    Directory of Open Access Journals (Sweden)

    Stefan Rammelt

    Full Text Available ABSTRACT Foot and ankle fractures represent 12% of all pediatric fractures. Malleolar fractures are the most frequent injuries of the lower limbs. Hindfoot and midfoot fractures are rare, but inadequate treatment for these fractures may results in compartment syndrome, three-dimensional deformities, avascular necrosis and early post-traumatic arthritis, which have a significant impact on overall foot and ankle function. Therefore, the challenges in treating these injuries in children are to achieve adequate diagnosis and precise treatment, while avoiding complications. The objective of the treatment is to restore normal anatomy and the correct articular relationship between the bones in this region. Moreover, the treatment needs to be planned according to articular involvement, lower-limb alignment, ligament stability and age. This article provides a review on this topic and presents the scientific evidence for appropriate treatment of these lesions.

  19. Data on the number and frequency of scientific literature citations for established medulloblastoma cell lines

    Directory of Open Access Journals (Sweden)

    D.P. Ivanov

    2016-12-01

    Full Text Available This article collates information about the number of scientific articles mentioning each of the established medulloblastoma cell lines, derived through a systematic search of Web of Science, Scopus and Google Scholar in 2016. The data for each cell line have been presented as raw number of citations, percentage share of the total citations for each search engine and as an average percentage between the three search engines. In order to correct for the time since each cell line has been in use, the raw citation data have also been divided by the number of years since the derivation of each cell line. This is a supporting article for a review of in vitro models of medulloblastoma published in “in vitro models of medulloblastoma: choosing the right tool for the job” (D.P. Ivanov, D.A. Walker, B. Coyle, A.M. Grabowska, 2016 [1].

  20. Dreaming scientists and scientific dreamers: Freud as a reader of French dream literature.

    Science.gov (United States)

    Carroy, Jacqueline

    2006-03-01

    The argument of this paper is to situate The Interpretation of Dreams within an historical context. It is, therefore, impossible to believe Freud entirely when he staged himself in his letters to Fliess as a mere discoverer. In reality Freud also felt he belonged to a learned community of dream specialists, whom I call "dreaming scientists" and "scientific dreamers." Instead of speaking, as Ellenberger does, in terms of influence, I will be offering as an example a portrait of Freud as a reader of two French authors, Maury, and indirectly, Hervey de Saint-Denys. I will analyze how Freud staged himself as replacing Maury and dreaming sometimes like Hervey de Saint-Denys. My premise in this work is that we must forget Freud, in order to adventure into a learned dream culture peculiar to the nineteenth century. Only afterwards can we come back to Freud and place him in this context as a creative heir.

  1. The Use of Current Media in Literature and Composition at the Community College Level.

    Science.gov (United States)

    Laughlin, Jody

    Current media--films, videos, television programs, advertising in both print and television, and newspaper and magazine articles--can be successfully employed in college literature and composition classes, enhancing the learning environment by involving those students who might otherwise show disinterest. For example, a unit on pornography,…

  2. Prostate cancer, treatment modalities and complications: an evaluation of the scientific literature

    Energy Technology Data Exchange (ETDEWEB)

    Santos-Filho, Sebastiao David; Fonseca, Adenilson de Souza da; Bernardo-Filho, Mario [Universidade do Estado do Rio de Janeiro (UERJ), RJ (Brazil). Inst. de Biologia Roberto Alcantara Gomes. Dept. de Biofisica e Biometria]. E-mail: santos-filho@uer.br; Missailids, Sotiris [The Open University, Milton Keynes (United Kingdom). Dept. of Chemistry and Analytical Sciences

    2008-12-15

    Prostate (PR) cancer (CA) is one of the most common malignant neoplasms in men all over the world. In general, if prostate cancer (PC) is detected early, treatment usually involves either surgical removal of the prostate or radiotherapy (RT). Hormone Therapy (HT) or chemotherapy (CH) is the preferred treatment for more advanced cases of PC or if CA spreads beyond the PT. A number of complications, such as urinary incontinence (IU) or erectile dysfunction (ED), can be associated with some modalities of treatment of the PC. The aim of this work is to evaluate, in PubMed, the number of publications related with prostate cancer and the main modalities of treatment, as well as some clinical complications. The searches were performed in PubMed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi) in the period 1950 to 2008 using the words: CA, CA and PR or penis or testis, CA and PR and RT, CA and PR and surgery (SU), CA and PR and CH and, CA and PR and HT and CA and PR and RT and IU or ED, CA and PR and SU and IU or ED, CA and PR and CH and IU or ED and, CA and PR and HT and CH and IU or ED, and (V) PC and the same modalities of treatment. The data was obtained on July 20th, 2008. PC, as expected has been cited extensively and surgery has been identified as the most widely referenced modality of treatment. Furthermore, urinary incontinence and erectile dysfunction are important complications that have attracted significant scientific interest. In conclusion, these findings have shown the relevance of the PubMed to analyze quantitatively the publications in cancer and this information could be worthwhile in aiding the comprehension of some clinical aspects related with PC, as well as the development of preventative actions. The analysis of the scientific interest, considering the number of publications in the PubMed, reveals research trends in the field and demonstrates the importance of the surgical procedures in the treatment of the prostate cancer. Moreover, this finding is

  3. Scientific literature on teaching strategies used in biochemistry courses: a systematic review

    Directory of Open Access Journals (Sweden)

    Joice Trindade Silveira

    2016-12-01

    Full Text Available The aim of this study was to know teaching strategies undertaken by biochemistry teachers in higher education. A systematic review of the literature was conducted, and was included articles developed in Brazilian universities, published in the 2004-2015 period, with descriptors learning, biochemistry and graduation. 40 publications were found, and 2004 was the year with most studies (n=7. The most common activities were conducting experimental activity (32,5%, development of various teaching tools (22,5%, use of Problem-based Learning (20%, use of information technologies (17,5% and development courses (7,5%. Thus, it was observed that there are groups of teachers working with different teaching strategies seeking to improve student learning. The production and publication of knowledge in teaching in biochemistry can help this process.

  4. The unusual stability of TATB (1,3,5-triamino-2,4,6-trinitrobenzene): A review of the scientific literature

    Energy Technology Data Exchange (ETDEWEB)

    Rice, S.F.; Simpson, R.L.

    1990-07-04

    This review is intended as an up-to-date review of the scientific literature on TATB since its discovery as a high explosive. In particular, it focuses on clarifying our current understanding of the relationship between the structure of TATB and its unique thermal stability. We review a large number of different publications by many authors. A small portion of the work on TATB'' presented actually consists of experimental studies on TATB formulated as PBX-9502 or as LX-17. Where relevant, this distinction is indicated. However, inasmuch as this review focuses on thermal response and the relationship of chemical reactivity to the molecular and lattice structure of TATB as a pure material, results from these other formulations may not be directly applicable, and in general we have omitted them. 4 refs.

  5. An annotated bibliography of scientific literature on research and management activities conducted in Manitou Experimental Forest

    Science.gov (United States)

    Ilana Abrahamson

    2012-01-01

    The Manitou Experimental Forest (MEF) is part of the USDA Forest Service Rocky Mountain Research Station. Established in 1936, its early research focused on range and watershed management. Currently, the site is home to several meteorological, ecological and biological research initiatives. Our collaborators include the University of Colorado, Colorado State University...

  6. The GCRP Climate Health Assessment: From Scientific Literature to Climate Health Literacy

    Science.gov (United States)

    Crimmins, A. R.; Balbus, J. M.

    2016-12-01

    As noted by the new report from the US GCRP, the Impacts of Climate Change on Human Health in the United States: A Scientific Assessment, climate change is a significant threat to the health of the American people. Despite a growing awareness of the significance of climate change in general among Americans, however, recognition of the health significance of climate change is lacking. Not only are the general public and many climate scientists relatively uninformed about the myriad health implications of climate change; health professionals, including physicians and nurses, are in need of enhanced climate literacy. This presentation will provide an overview of the new GCRP Climate Health Assessment, introducing the audience to the systems thinking that underlies the assessment of health impacts, and reviewing frameworks that tie climate and earth systems phenomena to human vulnerability and health. The impacts on health through changes in temperature, precipitation, severity of weather extremes and climate variability, and alteration of ecosystems and phenology will be explored. The process of developing the assessment report will be discussed in the context of raising climate and health literacy within the federal government.

  7. Did the APA misrepresent the scientific literature to courts in support of homosexual custody?

    Science.gov (United States)

    Cameron, P; Cameron, K

    1997-05-01

    In 1994, American Psychological Association amicus briefs informed two state Supreme Courts that (a) homosexual parents are not more apt to have homosexual children; (b) lesbians "score significantly higher than heterosexual parents" on a measure of parental effectiveness; and (c) no differences between the children raised by homosexuals and nonhomosexuals had been found "regardless of the geographic region within the United States where the children were raised." In fact, the evidence from these briefs shows to the contrary that (a) homosexual parents are more apt to have homosexual children; (b) the findings on parental effectiveness consisted of 15 fathers being less verbal than 45 mothers; and (c) the finding of no differences between homosexually and heterosexually raised children consisted of investigators visiting 11 states to test 89 offspring of 83 lesbian vs. 81 children of 69 nonlesbian volunteers. The APA's support for gay rights in these briefs may have violated its own ethical principles that "psychologists base their statements on scientifically acceptable psychological findings and techniques with full recognition of the limits and uncertainties of such evidence" and that psychologists must "provide thorough discussion of the limitations of their data, especially where their work touches on social policy" (APA, 1981).

  8. Scientific publications in anesthesiology journals from East Asia: a 10-year survey of the literature.

    Science.gov (United States)

    Li, Zhi; Qiu, Li-Xin; Wu, Fei-Xiang; Yang, Li-Qun; Sun, Yu-Ming; Yu, Wei-Feng

    2011-04-01

    The scientific publications in anesthesiology research from East Asian authors have not been reported yet. The present study was designed to analyze the contribution of articles from East Asia to anesthesiology research. Articles published in 17 journals in anesthesiology originating from Japan, China, and South Korea from 2000 to 2009 were retrieved from the PubMed database and Web of Science. From 2000 to 2009, there were 3,076 articles published from East Asia. During this period, there were a notable decrease in publications from Japan and modest increases in publications from both China and South Korea. The average 5-year impact factor of the published articles was similar among the three regions, and China had the highest average number of citations to each article. Anesthesia & Analgesia published more articles than any other journal from all three regions. Our analysis showed that Japan was the most productive region in East Asia, but there was a notable decrease in publications from Japan in 2000-2009. The impact factor of the articles suggests similar levels of scholarship. Anesthesia & Analgesia was the most popular journal in East Asia.

  9. Scientific literature on Twitter as subject research : preliminary findings based on bibliometric analysis

    OpenAIRE

    Fausto, Sibele; Aventurier, Pascal

    2015-01-01

    Background and purpose[br/] [br/] Since its launch in 2006, Internet platform Twitter has rapidly expanded. Despite being behind services like Facebook (1.3 billion active users) and WhatsApp (500 million), this platform currently has about 284 million active users worldwide, with 500 million Tweets being sent out every day, in more than 35 different languages (Twitter, 2015). In 2014 the eMarketer Consultancy predicted that Twitter should reach 300 million monthly active users by 2016,...

  10. A bibliometric study of scientific literature in Scopus on botanicals for treatment of androgenetic alopecia.

    Science.gov (United States)

    Rondanelli, Mariangela; Perna, Simone; Peroni, Gabriella; Guido, Davide

    2016-06-01

    In androgenetic alopecia, a number of botanicals are available that can effectively slow or reduce hair loss and inflammation or stimulate partial hair regrowth. The aim of this study was to provide a descriptive overview of the impact and production of literature on botanicals used for androgenetic alopecia and to perform a citation analysis of the related research articles. We searched for "alopecia" OR "androgenetic alopecia" OR "hair loss" AND "Camelia sinensis" OR (and other 15 botanicals) in ARTICLE (Title/Abstract/Keyword) in Scopus database. A total of 29 references, that is, research articles, were retrieved by SCOPUS search, and 93.1% had been published since 2000. The majority (48.3%) describe applications of hair grow stimulants, followed by inhibitors of 5-alpha-reductase applications (27.6%), and studies concerning inhibitors of inflammation (24.1%). The citation analysis revealed a growing interest for this topic and the papers on hair grow stimulants are most cited. Citation trend of inhibition of 5-alpha-reductase articles is growing in the last years. This study has highlighted three important aspects: (1) growing interest for this topic; (2) evidences mainly in hair grow stimulants and recently in the inhibition of 5-alpha-reductase, as demonstrated by article and citation counts across years; (3) in addition, all major studies have been focused on green tea epigallocatechin-3-gallate, Serenoa repens, Citrullus colocynthis and Cuscuta reflexa. © 2015 Wiley Periodicals, Inc.

  11. Current state of ethics literature synthesis: a systematic review of reviews.

    Science.gov (United States)

    Mertz, Marcel; Kahrass, Hannes; Strech, Daniel

    2016-10-03

    Modern standards for evidence-based decision making in clinical care and public health still rely solely on eminence-based input when it comes to normative ethical considerations. Manuals for clinical guideline development or health technology assessment (HTA) do not explain how to search, analyze, and synthesize relevant normative information in a systematic and transparent manner. In the scientific literature, however, systematic or semi-systematic reviews of ethics literature already exist, and scholarly debate on their opportunities and limitations has recently bloomed. A systematic review was performed of all existing systematic or semi-systematic reviews for normative ethics literature on medical topics. The study further assessed how these reviews report on their methods for search, selection, analysis, and synthesis of ethics literature. We identified 84 reviews published between 1997 and 2015 in 65 different journals and demonstrated an increasing publication rate for this type of review. While most reviews reported on different aspects of search and selection methods, reporting was much less explicit for aspects of analysis and synthesis methods: 31 % did not fulfill any criteria related to the reporting of analysis methods; for example, only 25 % of the reviews reported the ethical approach needed to analyze and synthesize normative information. While reviews of ethics literature are increasingly published, their reporting quality for analysis and synthesis of normative information should be improved. Guiding questions are: What was the applied ethical approach and technical procedure for identifying and extracting the relevant normative information units? What method and procedure was employed for synthesizing normative information? Experts and stakeholders from bioethics, HTA, guideline development, health care professionals, and patient organizations should work together to further develop this area of evidence-based health care.

  12. 科技查新工作质量的影响因素分析%Factors influencing the assessment of scientific literature novelty

    Institute of Scientific and Technical Information of China (English)

    吕淑云

    2016-01-01

    After a discussion of how to abstract and summarize the literature novelty points, how to use the retrieval words and how to write the conclusion in assessment of scientific literature novelty, the major factors influencing the assessment of scientific literature novelty were analyzed with suggestions put forward for improving the assessment of scientific literature novelty.%探讨了科技查新过程中查新点的提炼与归纳、查新检索用词及查新结论的撰写,分析了影响查新质量的主要因素,并提出了提高查新工作质量的建议。

  13. Continuous, Dynamic and Comprehensive Article-Level Evaluation of Scientific Literature

    CERN Document Server

    Wang, Xianwen; Yang, Yang

    2014-01-01

    It is time to make changes to the current research evaluation system, which is built on the journal selection. In this study, we propose the idea of continuous, dynamic and comprehensive article-level-evaluation based on article-level-metrics. Different kinds of metrics are integrated into a comprehensive indicator, which could quantify both the academic and societal impact of the article. At different phases after the publication, the weights of different metrics are dynamically adjusted to mediate the long term and short term impact of the paper. Using the sample data, we make empirical study of the article-level-evaluation method.

  14. Quantitative analysis and relevant features of the scientific literature related to SAXS and SANS

    Energy Technology Data Exchange (ETDEWEB)

    Craievich, Aldo F [Institute of Physics, University of Sao Paulo, Sao Paulo-SP (Brazil); Fischer, Hannes, E-mail: craievich@if.usp.b, E-mail: hannes@jacto.com.b [Jacto Maquinas Agricolas SA, Pompeia-SP (Brazil)

    2010-10-01

    We present and discuss here numerical information derived from a systematic searching of scientific papers related to SAXS and SANS published in indexed journals - from 1945 until nowadays - recorded by the Web of Science Data Bank (WoS). We have detected interesting features regarding the time dependence of the number of papers/year, N(t), indicating the existence of three well-defined periods of historical evolution with rather well-defined boundaries. All three periods exhibit a positive and approximately linear variation of N(t) but, at the two transitions between periods, the rate of growth exhibits clear and strong increases. Differences of the historical evolutions in the numbers of papers/year related to SAXS and to SANS were established. The different behaviours regarding the numbers of papers/year related to SAXS and to SANS and the existence of three different and well defined periods for N(t) can be qualitatively understood as a consequence of the progressive and increasing availability along the last three decades of very brilliant synchrotrons, last generation commercial X-ray sources, new neutron facilities, powerful computers and novel theoretical approaches for SAS data analysis. The rates of growth in the number of papers/year published by authors from a set of different countries are approximately constant along the last two decades. For other countries we have detected a slowing down effect in the number of papers/year while a clear acceleration could be noticed for the production of SAS papers by authors from several emerging countries. These opposite trends compensate in such a way that the number of SAS (SAXS+SAXS) articles published per year all around the world maintained a vigorous linear growth - during more than 20 years - at a constant rate of 60 papers/year, without any indication of eventual saturation. The observed distribution of articles among different journals indicates that a very high fraction of the volume of SAS research is

  15. The Short Stay Unit as a new option for hospitals: A review of the scientific literature

    Science.gov (United States)

    Damiani, Gianfranco; Pinnarelli, Luigi; Sommella, Lorenzo; Vena, Valentina; Magrini, Patrizia; Ricciardi, Walter

    2011-01-01

    Summary Background The short stay unit (SSU) is a ward providing targeted care for patients requiring brief hospitalization and dischargeable as soon as clinical conditions are resolved. Therefore, SSU is an alternative to the ordinary ward (OW) for the treatment of selected patients. The SSU model has been tested in only a few hospitals, and the literature lacks systematic evaluation of the impact of SSU use. The aim of our study was to evaluate the use of SSUs in terms of length of hospital stay, mortality and readmission rate. Material/Methods A random effect meta-analysis was carried out by consulting electronic databases. Studies were selected that focused on comparison between use of SSUs and OWs. Mean difference of length of stay was calculated within 95% confidence intervals. Results Six articles were selected, for a total of 21 264 patients. The estimated mean difference was −3.06 days (95% CI −4.71, −1.40) in favor of the SSU. The selected articles did not show any differences in terms of mortality and readmission rate. Conclusions Use of SSUs could reduce patient length of stay in hospital, representing an alternative to the ordinary ward for selected patients. A shorter period of hospitalization could reduce the risk of hospital-acquired infections, increase patient satisfaction and yield more efficient use of hospital beds. Findings of this study are useful for institutional, managerial and clinical decision-makers regarding the implementation of the SSU in a hospital setting, and for better management of continuity of care. PMID:21629205

  16. The relation between tourism and tecnology clusters and its impacts to the local development: a bibliometric study of scientific literature

    Directory of Open Access Journals (Sweden)

    Cristina Martins

    2016-03-01

    Full Text Available This paper intends to investigate the scientific literature on the relation between tourism and technology clusters (TourTech in promoting local development on the databases Business Source Complete of the Online Research Databases (EBSCO and Leisure Tourism Database (CABI until the year 2014. With a mixed approach (qualitative and quantitative, the research is classified as descriptive and bibliographic. The strategy adopted for data collection used bibliometric criteria and the data analysis applied was content analysis. The results showed that there are some possible theoretical gaps to be developed: not only about the conection between tourism clusters and technology clusters for local development, but also the relation between tourism and technology clusters and their impact to promote innovation that can improve the local development and finally, how the investments to develop a cluster individually can impact on the development of the other.

  17. Current use of medical eponyms – a need for global uniformity in scientific publications

    Directory of Open Access Journals (Sweden)

    Arora Nalini

    2009-03-01

    Full Text Available Abstract Background Although eponyms are widely used in medicine, they arbitrarily alternate between the possessive and nonpossessive forms. As very little is known regarding extent and distribution of this variation, the present study was planned to assess current use of eponymous term taking "Down syndrome" and "Down's syndrome" as an example. Methods This study was carried out in two phases – first phase in 1998 and second phase in 2008. In the first phase, we manually searched the terms "Down syndrome" and "Down's syndrome" in the indexes of 70 medical books, and 46 medical journals. In second phase, we performed PubMed search with both the terms, followed by text-word search for the same. Results In the first phase, there was an overall tilt towards possessive form – 62(53.4% "Down's syndrome" versus 54(46.6% "Down syndrome." However, the American publications preferred the nonpossesive form when compared with their European counterpart (40/50 versus 14/66; P Conclusion Inconsistency in the use of medical eponyms remains a major problem in literature search. Because of linguistic simplicity and technical advantages, the nonpossessive form should be used uniformly worldwide.

  18. The First Decade with the Swedish Prescribed Drug Register - A Systematic Review of the Output in the Scientific Literature.

    Science.gov (United States)

    Wallerstedt, Susanna M; Wettermark, Björn; Hoffmann, Mikael

    2016-11-01

    The aim of this study was to quantify and characterize the scientific output from the Swedish Prescribed Drug Register (SPDR) the first decade after its establishment. A systematic literature search was performed in Medline, EMBASE and PubMed (2005-2014). Additional publications were identified by personal knowledge, reference lists, contact with active authors and a citation search in Web of Sciences. Publications using SPDR data were included in the analysis and characterized regarding study type, presence of patient-level record linkage, target population and topic. A total of 719 publications were identified in the literature search and an additional 148 by other strategies. Three hundred and thirty-eight studies fulfilled the inclusion criteria. The majority were analytic (n = 166; 49.1%) or descriptive (n = 100; 29.5%). The remaining studies focused on validation (n = 20; 5.9%), health economics (n = 16; 4.7%) or miscellaneous (n = 36; 10.7%). The analytic studies investigating effects of drug exposure focused mainly on safety (n = 46) and/or effectiveness (n = 24). The first publications appeared in 2007 (n = 6), and in 2014, 90 articles using SPDR were published. Over the years, linkage with other registers using the personal identity number increased (0-88.9% of the publications). The population was often selected by age (49.7%), condition (45.0%) and/or drug (22.8%) and concerned predominantly psychiatric (29.0%) and cardiovascular (20.4%) diseases. In conclusion, this study illustrates that the establishment of a nationwide individual-based register on dispensed prescription drugs facilitates an encouraging development of pharmacoepidemiological research, both regarding the number of publications and the scientific level of the analyses.

  19. Analysis of the production of scientific literature in clinical research areas in Physiotherapy between 2005 and 2009

    Directory of Open Access Journals (Sweden)

    Torres-Narváez Martha

    2012-04-01

    Full Text Available Objective: characterize the behavior of clinical research in Physiotherapy, through the analysis of theproduction of scientific literature in a period of five years in order to identify areas of concentrationand dispersion, collaborative research and types of clinical studies have conducted. Methods andmaterials: descriptive study on the papers in Medline/PubMed from 2005-2009. Were considereda total 404 publications, clinical trials and epidemiological studies side, analyzed according to thepercentage distribution of articles by clinical area, year of publication, and institutional affiliation ofresearchers. Results: It found a greater number of trials (93% systematic reviews represented thegreatest number of epidemiological studies side. The clinical areas pulmonary and cardiovascularaccount for 65% of scientific publications in the studies analyzed. The year with highest numberof publications was 2008. Half of the clinical research produced in this five-year have affiliationwith academic institutions, and secondly, studies conducted in hospitals. Conclusions: the clinicalresearch publications in Physiotherapy in Medline/PubMed registered show sustained activity ofscientific production in the pulmonary and cardiovascular areas, consistent with the major healthconcerns in the world. The findings suggest that the ability of physiotherapists to develop qualityresearch, use and transfer of results into clinical practice should achieve greater development.

  20. Functioning and effectiveness of electronic control devices such as the TASER® M- and X-series: a review of the current literature.

    Science.gov (United States)

    Kunz, Sebastian N; Zinka, Bettina; Fieseler, Sybille; Graw, Matthias; Peschel, Oliver

    2012-11-01

    Conducted electrical weapons (CEWs) such as the TASER(®) M- and X-series deliver short high-voltage, low-current energy pulses to temporarily paralyze a person by causing electrical interruption of the body's normal energy pulses. Despite many scientific publications, which classify the health risks of an appropriate use of the TASER device as minor, there still is a continuous uncertainty about possible side effects with human application. Based on a literature search of the National Library of Medicine's MEDLINE database's PubMed system of current publications, the following article describes the mechanisms by which the device operates and discusses possible pathophysiological consequences. The majority of current human literature has not found evidence of clinical relevant pathophysiological effects during and after an exposure of professionally applied CEWs. However, to be able to exclude possible health risks, a medical checkup of people who have been exposed to CEWs is essential.

  1. Detecting diseases of neglected seminal vesicles using imaging modalities: A review of current literature.

    Science.gov (United States)

    Dagur, Gautam; Warren, Kelly; Suh, Yiji; Singh, Navjot; Khan, Sardar A

    2016-05-01

    Seminal vesicles (SVs) are sex accessory organs and part of male genitourinary system. They play a critical role in male fertility. Diseases of the SVs, usually results in infertility. Diseases of the SVs are extremely rare and are infrequently reported in the literature. We address the current literature of SV pathologies, symptoms, diagnosis, and treatment options. We review the clinical importance of SVs from PubMed. The current imaging modalities and instrumentation that help diagnose SV diseases are reviewed. Common pathologies including, infection, cysts, tumors, and congenital diseases of the SVs are addressed. Many times symptoms of hematospermia, pain, irritative and obstructive lower urinary tract symptoms, and infertility are presented in patients with SV diseases.

  2. Lithium and suicide in mood disorders: Updated meta-review of the scientific literature.

    Science.gov (United States)

    Smith, Katharine A; Cipriani, Andrea

    2017-09-12

    Suicide and suicidal behaviour are increased in mood disorders, particularly bipolar disorders. Observational studies and small randomized controlled trials (RCTs) support the idea that taking lithium is associated with a reduction in these rates. This paper aims to review the best evidence for the effect of lithium on rates of suicide and self harm. We searched PubMed, PsycINFO, and the Cochrane Library systematically for systematic reviews and meta-analyses of RCTs of lithium and suicide and self harm published between January 1980 and June 2017. In the case of multiple publications on the same topic, only the most recent or most comprehensive review was considered. A large number of reviews were identified, but only 16 publications were systematic reviews. Of these, three systematic reviews of lithium and suicide rates and one of lithium and self harm confined only to RCTs were identified. Despite some methodological concerns and heterogeneity in terms of participants, diagnoses, comparators, durations, and phase of illness, the evidence to date is overwhelmingly in favour of lithium as an antisuicidal agent, even balanced against any potential disadvantages of its use in regular clinical practice. The anti-suicidal effects of lithium have been consistently reported over the past 40 years. The most robust evidence comes from RCTs, but these results are also discussed in the context of the difficulties in conducting high quality studies in this area, and the supporting evidence that observational and non-randomized studies can also provide. Given this evidence, however, the use of lithium is still underrepresented in clinical practice and should be incorporated more assertively into current guidelines. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  3. Current Efforts in European Projects to Facilitate the Sharing of Scientific Observation Data

    Science.gov (United States)

    Bredel, Henning; Rieke, Matthes; Maso, Joan; Jirka, Simon; Stasch, Christoph

    2017-04-01

    This presentation is intended to provide an overview of currently ongoing efforts in European projects to facilitate and promote the interoperable sharing of scientific observation data. This will be illustrated through two examples: a prototypical portal developed in the ConnectinGEO project for matching available (in-situ) data sources to the needs of users and a joint activity of several research projects to harmonise the usage of the OGC Sensor Web Enablement standards for providing access to marine observation data. ENEON is an activity initiated by the European ConnectinGEO project to coordinate in-situ Earth observation networks with the aim to harmonise the access to observations, improve discoverability, and identify/close gaps in European earth observation data resources. In this context, ENEON commons has been developed as a supporting Web portal for facilitating discovery, access, re-use and creation of knowledge about observations, networks, and related activities (e.g. projects). The portal is based on developments resulting from the European WaterInnEU project and has been extended to cover the requirements for handling knowledge about in-situ earth observation networks. A first prototype of the portal was completed in January 2017 which offers functionality for interactive discussion, information exchange and querying information about data delivered by different observation networks. Within this presentation, we will introduce the presented prototype and initiate a discussion about potential future work directions. The second example concerns the harmonisation of data exchange in the marine domain. There are many organisation who operate ocean observatories or data archives. In recent years, the application of the OGC Sensor Web Enablement (SWE) technology has become more and more popular to increase the interoperability between marine observation networks. However, as the SWE standards were intentionally designed in a domain independent manner

  4. Taxonomic Review of Classical and Current Literature on the Perennial American Family Forest Problem

    Directory of Open Access Journals (Sweden)

    Thomas J. Straka

    2011-08-01

    Full Text Available One of the fundamental issues in American forest policy has been the small forest ownership problem. Early in the twentieth century, it was called the farm forestry problem, later, the nonindustrial private forest problem, and today, the family forest problem. Family forest owners are thought to manage their lands in a suboptimal manner resulting in low forest productivity relative to other ownership groups. This can lead to future timber supply problems. The exact nature of the problem, especially its social and economic basis, was a common subject of early forestry research studies. This article includes many of the major nonindustrial private forest or family forest studies, from early to current, and classifies them both by themes used by other authors and categories that relate to major research areas in the current literature. A major focus of this literature deals with promoting management on family forest holdings and possible land management incentives and disincentives. Natural trends in family forest ownership, like parcelization, also impact upon forest management opportunities. By developing a taxonomy that classifies these studies by research objective, methodology, owner motivation, and problem definition, this article serves to organize the family forest literature in a manner that provides a temporal framework for better understanding the historical motivation for and development of family forest research in the United States.

  5. Current methods of sedation in dental patients - a systematic review of the literature

    Science.gov (United States)

    Silvestre-Rangil, Javier; Cutando-Soriano, Antonio; López-Jiménez, Julián

    2016-01-01

    Objetive The main objective of this systematic literature review is to identify the safest and most effective sedative drugs so as to ensure successful sedation with as few complications as possible. Study Design A systematic literature review of the PubMed MEDLINE database was carried out using the key words “conscious sedation,” “drugs,” and “dentistry.” A total of 1,827 scientific articles were found, and these were narrowed down to 473 articles after applying inclusion and exclusion criteria. These 473 studies were then individually assessed for their suitability for inclusion in this literature review. Results A total of 21 studies were selected due to their rigorous study design and conduciveness to further, more exhaustive analysis. The selected studies included a total of 1,0003 patients classified as ASA I or II. Midazolam was the drug most frequently used for successful sedation in dental surgical procedures. Ketamine also proved very useful when administered intranasally, although some side effects were observed when delivered via other routes of administration. Both propofol and nitrous oxide (N2O) are also effective sedative drugs. Conclusions Midazolam is the drug most commonly used to induce moderate sedation in dental surgical procedures, and it is also very safe. Other sedative drugs like ketamine, dexmedetomidine and propofol have also been proven safe and effective; however, further comparative clinical studies are needed to better demonstrate which of these are the safest and most effective. Key words:Conscious sedation, drugs, dentistry. PMID:27475684

  6. Compilation of current literature on seals, closures, and leakage for radioactive material packagings

    Energy Technology Data Exchange (ETDEWEB)

    Warrant, M.M.; Ottinger, C.A.

    1989-01-01

    This report presents an overview of the features that affect the sealing capability of radioactive material packagings currently certified by the US Nuclear Regulatory Commission. The report is based on a review of current literature on seals, closures, and leakage for radioactive material packagings. Federal regulations that relate to the sealing capability of radioactive material packagings, as well as basic equations for leakage calculations and some of the available leakage test procedures are presented. The factors which affect the sealing capability of a closure, including the properties of the sealing surfaces, the gasket material, the closure method and the contents are discussed in qualitative terms. Information on the general properties of both elastomer and metal gasket materials and some specific designs are presented. A summary of the seal material, closure method, and leakage tests for currently certified packagings with large diameter seals is provided. 18 figs., 9 tabs.

  7. Todai Scientific Information Retrieval (TSIR-1) System. II. Generation of a Scientific Literature Data Base in a Center-Oriented Format by a Tape-to-Tape Conversion of CAS SDF Data Base

    Science.gov (United States)

    And Others; Yammoto, Takeo

    1972-01-01

    Conversion of the Chemical Abstract Service scientific literature data base from Standard Distribution Format to a center-oriented file format, STF, is described. A tape file format is described in which variable length logical records, possibly longer than the blocksize, may be stored safely. (7 references) (Author/NH)

  8. Genetic update on inflammatory factors in ulcerative colitis: Review of the current literature

    Institute of Scientific and Technical Information of China (English)

    Patricia; Sarlos; Erzsebet; Kovesdi; Lili; Magyari; Zsolt; Banfai; Andras; Szabo; Andras; Javorhazy; Bela; Melegh

    2014-01-01

    Ulcerative colitis(UC) is one of the main types of inflammatory bowel disease, which is caused by dysregulated immune responses in genetically predisposed individuals. Several genetic factors, including interleukin and interleukin receptor gene polymorphisms and other inflammation-related genes play central role in mediating and modulating the inflammation in the human body, thereby these can be the main cause of development of the disease. It is clear these data are very important for understanding the base of the disease, especially in terms of clinical utility and validity, but summarized literature is exiguous for challenge health specialist that can used in the clinical practice nowadays. This review summarizes the current literature on inflammationrelated genetic polymorphisms which are associated with UC. We performed an electronic search of Pubmed Database among publications of the last 10 years, using the following medical subject heading terms: UC, ulcerative colitis, inflammation, genes, polymorphisms, and susceptibility.

  9. National and International Migration:Reflections on Literature and Some Current Research1

    Institute of Scientific and Technical Information of China (English)

    Nicholas Tapp(Wang Fuwen)

    2013-01-01

    This article gives a review on literature and some current research relevant to na-tional and international migration , and examines the connections between such research in a na-tional context , and the research on international migration .The approaches to migration in migra-tion studies are very complex , and the author suggested that we need to pay attention to all three approaches contrasted by Solinger:the one based on rational calculation , the one based on stress-ing the historico-structural conditions and the one based on social networking analysis .The au-thor also stresses the importance of a network approach taken from the sociology of John Urry in the studies of both national and international migration , and the need to see movement as prima-ry, and productive of place , as much recent anthropological literature has stressed .

  10. STUDY OF CURRENT APPROACHES FOR WEB PUBLISHING OF OPEN SCIENTIFIC DATA

    Directory of Open Access Journals (Sweden)

    D. I. Mouromtsev

    2015-11-01

    Full Text Available Subject of Study. The subject of study of this work is closely related to the development of tools and technologies for Internet publishing of open data in machine-readable formats with regard to data of universities, educational and research organizations and scientific laboratories. We analyze the trends in the publishing formats most commonly used including not only popular formats such as pdf, csv, excel, but also the Semantic Web formats such as RDF. The paper describes the way of scientific data publication in semantic formats on the example of import and convertation of the information from University database. Methods. We describe the methods of publication for scientific open data in the network consisting of a set of transformations of the original data sets to the final semantic representation. These transformation steps include data upload from a relational database, data mapping on the ontological model (schema and the generation of a set of RDF-triples corresponding to the initial database fragment. A description is given to the popular open data publishing systems, such as CKAN, VIVO, and others. OpenLink Virtuoso system is selected as the primary storage and data publication. The description of RDF data model is used as a way of presenting open data of ITMO University. Main Results. The authors have described the methods of scientific open data publication and identified their shortcomings. To demonstrate the efficiency of the proposed method of university open data publication, a software prototype has been developed available online at: http://lod.ifmo.ru/. The example of the system usage is also given. Practical Relevance. Implementation of the proposed approach will improve significantly the effect of the publication of university open data and make it available for third-party applications, such as applications for information retrieval about educational activities and research results, analysis of scientific activities in

  11. Current State of Terminology in Lithuania: Scientific Research, Management and Education

    Directory of Open Access Journals (Sweden)

    Albina Auksoriūtė

    2016-12-01

    Full Text Available Current State of Terminology in Lithuania: Scientific Research, Management and Education The article discusses the current state of terminology in Lithuania, presents terminological research carried out in the last five years, analyses ways of Lithuanian terminology management, and briefly overviews terminological education and teaching in Lithuania. Lithuanian terminological research is mostly carried out at the Institute of the Lithuanian Language and at universities and other research institutes. The largest part of terminological research is carried out at the Centre of Terminology of the Institute of the Lithuanian Language, which researches Lithuanian terminology and terminography, analyses the use of Lithuanian terminology in different fields. Three ways of terminology management are discussed: terminography, creation of term banks and databases and standardisation of terms. The number of term dictionaries published in Lithuania is rather considerable – over 600. The most productive period for publishing term dictionaries is from 1990 up to date. Between 1990–2013 more than 420 term dictionaries and special encyclopaedias were published. The main and most important terminology database in Lithuania is the Term Bank of the Republic of Lithuania (lt Lietuvos Respublikos terminų bankas, further – LTB, initiated in 2004. This bank is created as a common information system of state institutions administered by the State Commission of the Lithuanian Language (further – Language Commission. There are more than 237,000 term entries in LTB. The article discusses two more terminology databases containing Lithuanian terminology sources – IATE and EUROTERMBANK. The Lithuanian Standards Board, in addition to other work, prepares Lithuanian standards of terms and offers these terms to the Language Commission for evaluation. Since 2000, the Lithuanian Standards Board has been creating a database of standardised terms which currently contains

  12. Osteoporosis - "a silent killer". A review of the current literature from clinician and physiotherapist perspective

    OpenAIRE

    Kocjan, Janusz

    2015-01-01

    Kocjan Janusz. Osteoporosis - "a silent killer". A review of the current literature from clinician and physiotherapist perspective. Journal of Education, Health and Sport. 2015;5(7):63-70. ISSN 2391-8306. DOI 10.5281/zenodo.19173 http://ojs.ukw.edu.pl/index.php/johs/article/view/2015%3B5%287%29%3A63-70 https://pbn.nauka.gov.pl/works/576516 http://dx.doi.org/10.5281/zenodo.19173 Formerly Journal of Health Sciences. ISSN 1429-9623 / 2300-665X. Archives 2011 – 201...

  13. What's in a Name: Is “Evolutionary Psychology” Eclipsing “Sociobiology” in the Scientific Literature?

    Directory of Open Access Journals (Sweden)

    Gregory D. Webster

    2007-10-01

    Full Text Available Is the term “evolutionary psychology” supplanting “sociobiology” in the scientific literature? How influential was E. O. Wilson's (1975 book, Sociobiology, in establishing the discipline of the same name? Similarly, how influential were the two Tooby-Cosmides chapters appearing in The Adapted Mind (Cosmides and Tooby, 1992; Tooby and Cosmides, 1992 in establishing evolutionary psychology as a viable outgrowth of sociobiology? The purpose of the present research was to answer these questions using quantitative analyses of publication trends. The Internet search engine Google Scholar was used to count the number of hits (i.e., the number of scholarly works, citations, etc. for “sociobiology” and “evolutionary psychology” separately per year from 1960 to 2003. Interrupted time-series analyses revealed significant increases (intercept shifts for sociobiology hits between 1974 and 1975, and for evolutionary psychology hits between 1991 and 1992. Evolutionary psychology hits also experienced a significant increase in change-over-time (a slope shift between 1991 and 1992. Growth curve analyses revealed that the rate of growth for evolutionary psychology, which was accelerating over time, was significantly greater than that for sociobiology, which was decelerating. The implications of these findings for understanding the histories of sociobiology and evolutionary psychology are discussed.

  14. Detection of drug-drug interactions through data mining studies using clinical sources, scientific literature and social media.

    Science.gov (United States)

    Vilar, Santiago; Friedman, Carol; Hripcsak, George

    2017-02-17

    Drug-drug interactions (DDIs) constitute an important concern in drug development and postmarketing pharmacovigilance. They are considered the cause of many adverse drug effects exposing patients to higher risks and increasing public health system costs. Methods to follow-up and discover possible DDIs causing harm to the population are a primary aim of drug safety researchers. Here, we review different methodologies and recent advances using data mining to detect DDIs with impact on patients. We focus on data mining of different pharmacovigilance sources, such as the US Food and Drug Administration Adverse Event Reporting System and electronic health records from medical institutions, as well as on the diverse data mining studies that use narrative text available in the scientific biomedical literature and social media. We pay attention to the strengths but also further explain challenges related to these methods. Data mining has important applications in the analysis of DDIs showing the impact of the interactions as a cause of adverse effects, extracting interactions to create knowledge data sets and gold standards and in the discovery of novel and dangerous DDIs.

  15. Quality of pharmaceutical advertising and gender bias in medical journals (1998-2008): a review of the scientific literature.

    Science.gov (United States)

    Cambronero Saiz, Belén; Ruiz Cantero, María Teresa; Papí Gálvez, Natalia

    2012-01-01

    To review the scientific literature on pharmaceutical advertising aimed at health professionals in order to determine whether gender bias has decreased and the quality of information in pharmaceutical advertising has improved over time. We performed a content analysis of original articles dealing with medical drug promotion (1998-2008), according to quality criteria such as (a) the number, validity and accessibility of bibliographic references provided in pharmaceutical advertising and (b) the extent to which gender representations were consistent with the prevalence of the diseases. Databases: PUBMED, Medline, Scopus, Sociological Abstract, Eric and LILACS. We reviewed 31 articles that analyzed advertising in medical journals from 1975-2005 and were published between 1998 and 2008. We found that the number of references used to support pharmaceutical advertising claims increased from 1975 but that 50% of these references were not valid. There was a tendency to depict men in paid productive roles, while women appeared inside the home or in non-occupational social contexts. Advertisements for psychotropic and cardiovascular drugs overrepresented women and men respectively. The use of bibliographic references increased between 1998 and 2008. However, representation of traditional male-female roles was similar in 1975 and 2005. Pharmaceutical advertisements may contribute to reinforcing the perception that certain diseases are associated with the most frequently portrayed sex. Copyright © 2011 SESPAS. Published by Elsevier Espana. All rights reserved.

  16. Non-surgical spinal decompression therapy: does the scientific literature support efficacy claims made in the advertising media?

    Directory of Open Access Journals (Sweden)

    Daniel Dwain M

    2007-05-01

    Full Text Available Abstract Background Traction therapy has been utilized in the treatment of low back pain for decades. The most recent incarnation of traction therapy is non-surgical spinal decompression therapy which can cost over $100,000. This form of therapy has been heavily marketed to manual therapy professions and subsequently to the consumer. The purpose of this paper is to initiate a debate pertaining to the relationship between marketing claims and the scientific literature on non-surgical spinal decompression. Discussion Only one small randomized controlled trial and several lower level efficacy studies have been performed on spinal decompression therapy. In general the quality of these studies is questionable. Many of the studies were performed using the VAX-D® unit which places the patient in a prone position. Often companies utilize this research for their marketing although their units place the patient in the supine position. Summary Only limited evidence is available to warrant the routine use of non-surgical spinal decompression, particularly when many other well investigated, less expensive alternatives are available.

  17. Primary health care and disasters-the current state of the literature: what we know, gaps and next steps.

    Science.gov (United States)

    Redwood-Campbell, Lynda; Abrahams, Jonathan

    2011-06-01

    The 2009 Global Platform for Disaster Risk Reduction/Emergency Preparedness (DRR/EP) and the Hyogo Framework for Action 2005-2015 demonstrate increased international commitment to DRR/EP in addition to response and recovery. In addition, the World Health Report 2008 has re-focused the world's attention on the renewal of Primary Health Care (PHC) as a set of values/principles for all sectors. Evidence suggests that access to comprehensive PHC improves health outcomes and an integrated PHC approach may improve health in low income countries (LICs). Strong PHC health systems can provide stronger health emergency management, which reinforce each other for healthier communities. The global re-emphasis of PHC recently necessitates the health sector and the broader disaster community to consider health emergency management from the perspective of PHC. How PHC is being described in the literature related to disasters and the quality of this literature is reviewed. Identifying which topics/lessons learned are being published helps to identify key lessons learned, gaps and future directions. Fourteen major scientific and grey literature databases searched. Primary Health Care or Primary Care coupled with the term disaster was searched (title or abstract). The 2009 ISDR definition of disaster and the 1978 World Health Organization definition of Primary Health Care were used. 119 articles resulted. Literature characteristics; 16% research papers, only 29% target LICs, 8% of authors were from LICs, 7% clearly defined PHC, 50% used PHC to denote care provided by clinicians and 4% cited PHC values and principles. Most topics related to disaster response. Key topics; true need for PHC, mental health, chronic disease, models of PHC, importance of PHC soon after a natural disaster relative to acute care, methods of surge capacity, utilization patterns in recovery, access to vulnerable populations, rebuilding with the PHC approach and using current PHC infrastructure to build

  18. Similarities and Dissimilarities in Coauthorship Networks: Gestalt Theory as Explanation for Well-Ordered Collaboration Structures and Production of Scientific Literature.

    Science.gov (United States)

    Kretschmer, Hildrun

    2002-01-01

    Based on Gestalt theory, the author assumes the existence of a field-force equilibrium to explain how, according to the conciseness principle, mathematically precise gestalts could exist in coauthorship networks. Develops a mathematical function to describe these gestalts in scientific literature and discusses structural characteristics of…

  19. Introducing Scientific Literature to Honors General Chemistry Students: Teaching Information Literacy and the Nature of Research to First-Year Chemistry Students

    Science.gov (United States)

    Ferrer-Vinent, Ignacio J.; Bruehl, Margaret; Pan, Denise; Jones, Galin L.

    2015-01-01

    This paper describes the methodology and implementation of a case study introducing the scientific literature and creative experiment design to honors general chemistry laboratory students. The purpose of this study is to determine whether first-year chemistry students can develop information literacy skills while they engage with the primary…

  20. Introducing Scientific Literature to Honors General Chemistry Students: Teaching Information Literacy and the Nature of Research to First-Year Chemistry Students

    Science.gov (United States)

    Ferrer-Vinent, Ignacio J.; Bruehl, Margaret; Pan, Denise; Jones, Galin L.

    2015-01-01

    This paper describes the methodology and implementation of a case study introducing the scientific literature and creative experiment design to honors general chemistry laboratory students. The purpose of this study is to determine whether first-year chemistry students can develop information literacy skills while they engage with the primary…

  1. Similarities and Dissimilarities in Coauthorship Networks: Gestalt Theory as Explanation for Well-Ordered Collaboration Structures and Production of Scientific Literature.

    Science.gov (United States)

    Kretschmer, Hildrun

    2002-01-01

    Based on Gestalt theory, the author assumes the existence of a field-force equilibrium to explain how, according to the conciseness principle, mathematically precise gestalts could exist in coauthorship networks. Develops a mathematical function to describe these gestalts in scientific literature and discusses structural characteristics of…

  2. Ictal epileptic headache: a review of current literature and differentiation from migralepsy and other epilepsies.

    Science.gov (United States)

    Saitowitz, Zacharry; Flamini, Robert; Berenson, Frank

    2014-10-01

    Ictal headaches are increasingly becoming the focus of research as more data demonstrate headaches existing as a sole manifestation of an epileptic event. Due to the difficulty in diagnosing the event as an epileptic phenomenon as opposed to a migraine, the condition is often misdiagnosed. This paper seeks to review the current published literature on ictal epileptic headaches as well as provide differentiation between ictal headaches and similarly presenting conditions. In doing so, we hope to improve the diagnosis of ictal headaches and thus improve patient care. We review two case studies that exemplify the potential of multiple conditions with comparable symptoms to ictal headaches, and discuss how to differentiate the variable diagnoses. As of the writing of this paper, there is no universally agreed upon set of features of ictal headaches; however, reviewing the current literature, there do seem to be several features that should be noted when treating patients. More research on the pathophysiology of ictal epileptic headaches needs to be done before the condition can be fully understood.

  3. Volumetric intensity modulated arc therapy in lung cancer: Current literature review

    Directory of Open Access Journals (Sweden)

    Suresh B Rana

    2013-01-01

    Full Text Available The volumetric intensity modulated arc therapy (VMAT is a novel radiation technique that delivers a highly conformal radiation dose to the target by allowing the simultaneous variation of gantry rotation speed, dose rate and multiple-leaf collimators leaf positions. The aim of this study was to review the current literature on two VMAT systems, RapidArc and SmartArc with main focus on planning studies of lung cancer. A systematic review of available data was conducted using MEDLINE/PubMed with the keywords ′′lung′′ and "VMAT". The published data show that VMAT techniques have clear superiority over three-dimensional conformal radiation therapy with regard to improving dose conformity and sparing of organs at risks (OARs. The data indicates that for lung tumor VMAT and intensity modulated radiation therapy (IMRT provide equivalent dose homogeneity, dose conformity and target volume coverage; however, contradictory results were obtained in terms of OARs sparing. The major advantages of VMAT over IMRT are the reduction in the number of monitor units and faster treatment delivery times without compromising the quality of the treatment plans. Moreover, faster delivery time is more patient-friendly and it minimizes intra-fractional patient motion allowing treatment volumes stay within their respective treatment margins. Current literature data shows that VMAT can be a good option to treat lung cancer; however, data on clinical trials are still lacking. The clinical trials are essential to confirm the safety and efficacy of VMAT techniques.

  4. Robot-assisted laparoscopic partial nephrectomy: Current review of the technique and literature

    Directory of Open Access Journals (Sweden)

    Singh Iqbal

    2009-01-01

    Full Text Available Aim: To visit the operative technique and to review the current published English literature on the technique, and outcomes following robot-assisted laparoscopic partial nephrectomy (RPN. Materials and Methods: We searched the published English literature and the PubMed (TM for published series of ′robotic partial nephrectomy′ (RPN using the keywords; robot, robot-assisted laparoscopic partial nephrectomy, laparoscopic partial nephrectomy, partial nephrectomy and laparoscopic surgery. Results: The search yielded 15 major selected series of ′robotic partial nephrectomy′; these were reviewed, tracked and analysed in order to determine the current status and role of RPN in the management of early renal neoplasm(s, as a minimally invasive surgical alternative to open partial nephrectomy. A review of the initial peri-operative outcome of the 350 cases of select series of RPN reported in published English literature revealed a mean operating time, warm ischemia time, estimated blood loss and hospital stay, of 191 minutes, 25 minutes, 162 ml and 2.95 days, respectively. The overall computed mean complication rate of RPN in the present select series was about 7.4%. Conclusions: RPN is a safe, feasible and effective minimally invasive surgical alternative to laparoscopic partial nephrectomy for early stage (T 1 renal neoplasm(s. It has acceptable initial renal functional outcomes without the increased risk of major complications in experienced hands. Prospective randomised, controlled, comparative clinical trials with laparoscopic partial nephrectomy (LPN are the need of the day. While the initial oncological outcomes of RPN appear to be favourable, long-term data is awaited.

  5. Volunteered Geographic Information in Natural Hazard Analysis: A Systematic Literature Review of Current Approaches with a Focus on Preparedness and Mitigation

    Directory of Open Access Journals (Sweden)

    Carolin Klonner

    2016-06-01

    Full Text Available With the rise of new technologies, citizens can contribute to scientific research via Web 2.0 applications for collecting and distributing geospatial data. Integrating local knowledge, personal experience and up-to-date geoinformation indicates a promising approach for the theoretical framework and the methods of natural hazard analysis. Our systematic literature review aims at identifying current research and directions for future research in terms of Volunteered Geographic Information (VGI within natural hazard analysis. Focusing on both the preparedness and mitigation phase results in eleven articles from two literature databases. A qualitative analysis for in-depth information extraction reveals auspicious approaches regarding community engagement and data fusion, but also important research gaps. Mainly based in Europe and North America, the analysed studies deal primarily with floods and forest fires, applying geodata collected by trained citizens who are improving their knowledge and making their own interpretations. Yet, there is still a lack of common scientific terms and concepts. Future research can use these findings for the adaptation of scientific models of natural hazard analysis in order to enable the fusion of data from technical sensors and VGI. The development of such general methods shall contribute to establishing the user integration into various contexts, such as natural hazard analysis.

  6. Measuring currents in submarine canyons: technological and scientific progress in the past 30 years

    Science.gov (United States)

    Xu, J. P.

    2011-01-01

    The development and application of acoustic and optical technologies and of accurate positioning systems in the past 30 years have opened new frontiers in the submarine canyon research communities. This paper reviews several key advancements in both technology and science in the field of currents in submarine canyons since the1979 publication of Currents in Submarine Canyons and Other Sea Valleys by Francis Shepard and colleagues. Precise placements of high-resolution, high-frequency instruments have not only allowed researchers to collect new data that are essential for advancing and generalizing theories governing the canyon currents, but have also revealed new natural phenomena that challenge the understandings of the theorists and experimenters in their predictions of submarine canyon flow fields. Baroclinic motions at tidal frequencies, found to be intensified both up canyon and toward the canyon floor, dominate the flow field and control the sediment transport processes in submarine canyons. Turbidity currents are found to frequently occur in active submarine canyons such as Monterey Canyon. These turbidity currents have maximum speeds of nearly 200 cm/s, much smaller than the speeds of turbidity currents in geological time, but still very destructive. In addition to traditional Eulerian measurements, Lagrangian flow data are essential in quantifying water and sediment transport in submarine canyons. A concerted experiment with multiple monitoring stations along the canyon axis and on nearby shelves is required to characterize the storm-trigger mechanism for turbidity currents.

  7. The origin of the warped heliospheric current sheet. Scientific technical report

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    Wilcox, J.M.; Scherrer, P.H.; Hoeksema, J.T.

    1980-03-01

    The warped heliospheric current sheet in early 1976 is calculated from the observed photospheric magnetic field using a potential field method. Comparisons with measurements of the interplanetary magnetic field polarity in early 1976 obtained at several locations in the heliosphere at Helios I, Helios II, Pioneer XI and Earth show a rather detailed agreement between the computed current sheet and the observations. It appears that the large-scale structure of the warped heliospheric current sheet is determined by the structure of the photospheric magnetic field, and that 'ballerina skirt' effects may add small-scale ripples.

  8. The first step in the development of text mining technology for cancer risk assessment: identifying and organizing scientific evidence in risk assessment literature

    Directory of Open Access Journals (Sweden)

    Sun Lin

    2009-09-01

    Full Text Available Abstract Background One of the most neglected areas of biomedical Text Mining (TM is the development of systems based on carefully assessed user needs. We have recently investigated the user needs of an important task yet to be tackled by TM -- Cancer Risk Assessment (CRA. Here we take the first step towards the development of TM technology for the task: identifying and organizing the scientific evidence required for CRA in a taxonomy which is capable of supporting extensive data gathering from biomedical literature. Results The taxonomy is based on expert annotation of 1297 abstracts downloaded from relevant PubMed journals. It classifies 1742 unique keywords found in the corpus to 48 classes which specify core evidence required for CRA. We report promising results with inter-annotator agreement tests and automatic classification of PubMed abstracts to taxonomy classes. A simple user test is also reported in a near real-world CRA scenario which demonstrates along with other evaluation that the resources we have built are well-defined, accurate, and applicable in practice. Conclusion We present our annotation guidelines and a tool which we have designed for expert annotation of PubMed abstracts. A corpus annotated for keywords and document relevance is also presented, along with the taxonomy which organizes the keywords into classes defining core evidence for CRA. As demonstrated by the evaluation, the materials we have constructed provide a good basis for classification of CRA literature along multiple dimensions. They can support current manual CRA as well as facilitate the development of an approach based on TM. We discuss extending the taxonomy further via manual and machine learning approaches and the subsequent steps required to develop TM technology for the needs of CRA.

  9. Prevention of gastrointestinal bleeding due to stress ulceration: a review of current literature.

    Science.gov (United States)

    Pilkington, K B; Wagstaff, M J D; Greenwood, J E

    2012-03-01

    Our objective was to audit our current stress ulcer prophylaxis protocol (routine prescription of ranitidine and early enteral feeding) by identifying whether routine prescription of histamine-2 receptor antagonists or proton pump inhibitors as prophylaxis against stress-related mucosal disease and subsequent upper gastrointestinal bleeding is supported in the literature. We also aimed to ascertain what literature evidence supports the role of early enteral feeding as an adjunctive prophylactic therapy, as well as to search for burn-patient specific evidence, since burn patients are at high risk for developing this condition, with the aim of changing our practice. PubMed and Cochrane databases were searched for relevant articles, yielding seven randomised controlled trials comparing histamine-2 receptor antagonists and proton pump inhibitors in the prevention of upper gastrointestinal bleeding associated with stress-related mucosal disease and three separate meta-analyses. Despite level 1 clinical evidence, no significant difference in efficacy between histamine-2 receptor antagonists and proton pump inhibitor treatment groups was demonstrated. No significant difference was demonstrated in the incidence of nosocomial pneumonia between the two drugs given in this indication. However, enteral feeding was found to be safe and effective in preventing clinically significant upper gastrointestinal bleeding. Patients able to tolerate feeds demonstrated no additional benefit with concomitant pharmacological prophylactic therapy. Since all burn patients at the Royal Adelaide Hospital are fed from very early in their admission, the literature suggests that we, like our intensive care unit colleagues, should abolish our reliance on pharmacological prophylaxis, the routine prescription of which is not supported by the evidence.

  10. The Use of Medicinal Marijuana for Posttraumatic Stress Disorder: A Review of the Current Literature.

    Science.gov (United States)

    Yarnell, Stephanie

    2015-01-01

    Medicinal marijuana has already been legalized in over 23 states with more considering legalization. Despite the trend toward legalization, to date, there has been no systematic review of the existing literature for the efficacy of medicinal marijuana for many of the conditions for which it is proposed to treat. This study seeks to understand the current literature regarding the use of medicinal marijuana in the treatment of posttraumatic stress disorder (PTSD). PubMed and PsycINFO databases were searched until April 2014 for articles outlining outcomes of case files, control studies, and observational studies regarding the efficacy of medicinal marijuana in treating PTSD. Various combinations of the following search terms were used: marijuana, medicinal marijuana, cannabis, cannabinoid, PTSD, efficacy, trial, and neurobiology. Full text of each article was reviewed, and those directly addressing the question of efficacy of medicinal marijuana on PTSD symptomatology were included. Data were extracted from a total of 46 articles. Analysis revealed that most reports are correlational and observational in basis with a notable lack of randomized, controlled studies. Many of the published studies suggest a decrease in PTSD symptoms with marijuana use. Though the directionality of cannabis use and PTSD could not be fully differentiated at this time, there appears to also be a correlation between PTSD and problematic cannabis use. Despite this finding, there is a growing amount of neurobiological evidence and animal studies suggesting potential neurologically based reasons for the reported efficacy. Posttraumatic stress disorder is 1 of the approved conditions for medicinal marijuana in some states. While the literature to date is suggestive of a potential decrease in PTSD symptomatology with the use of medicinal marijuana, there is a notable lack of large-scale trials, making any final conclusions difficult to confirm at this time.

  11. The Impact of Sarcopenia on Survival and Complications in Surgical Oncology: A Review of the Current Literature

    Science.gov (United States)

    JOGLEKAR, SAVITA; NAU, PETER N.; MEZHIR, JAMES J.

    2016-01-01

    Sarcopenia is the subclinical loss of skeletal muscle and strength and has been extensively studied in both the cancer and surgical literature. Specifically, sarcopenia has gained significant recognition as an important prognostic factor for both complications and survival in cancer patients. Herein, we review the current literature to date highlighting the specific impact of sarcopenia in patients undergoing oncologic procedures. PMID:26310812

  12. The impact of sarcopenia on survival and complications in surgical oncology: A review of the current literature.

    Science.gov (United States)

    Joglekar, Savita; Nau, Peter N; Mezhir, James J

    2015-10-01

    Sarcopenia is the subclinical loss of skeletal muscle and strength and has been extensively studied in both the cancer and surgical literature. Specifically, sarcopenia has gained significant recognition as an important prognostic factor for both complications and survival in cancer patients. Herein, we review the current literature to date highlighting the specific impact of sarcopenia in patients undergoing oncologic procedures.

  13. [The representation of scientific publications of RAMS in WEB of science: evaluation of current indicators and prospects of their increasing].

    Science.gov (United States)

    Starodubtsev, V I; Kuznetsov, S L; Kurakova, N G; Tsvetkova, L A

    2012-01-01

    The contribution scientific publications of Russian Academy of Medical Sciences (RAMS) in the national publication stream, indexed by Web of Science over the past thirty years, was estimated. The indicators of publication activity that are necessary for the institutions of RAMS to achieve in short-term period the conformity with bibliometric indicators, established by Presidential Decree of May 7, 2012 (to increase the share of Russian publications in Web of Science to 2.44% in 2015) were calculated. It is shown that the current structure of global science, where publications in medicine make up for approximately one third of scientific publications in the world, set for RAMS scientists particularly difficult task: to double in three years the number of publications in Web of Sci. In the article are proposed the priorities and the necessary steps to fulfill this task.

  14. Current Debates on Variability in Child Welfare Decision-Making: A Selected Literature Review

    Directory of Open Access Journals (Sweden)

    Emily Keddell

    2014-11-01

    Full Text Available This article considers selected drivers of decision variability in child welfare decision-making and explores current debates in relation to these drivers. Covering the related influences of national orientation, risk and responsibility, inequality and poverty, evidence-based practice, constructions of abuse and its causes, domestic violence and cognitive processes, it discusses the literature in regards to how each of these influences decision variability. It situates these debates in relation to the ethical issue of variability and the equity issues that variability raises. I propose that despite the ecological complexity that drives decision variability, that improving internal (within-country decision consistency is still a valid goal. It may be that the use of annotated case examples, kind learning systems, and continued commitments to the social justice issues of inequality and individualisation can contribute to this goal.

  15. Treatment of pediculosis capitis: a critical appraisal of the current literature.

    Science.gov (United States)

    Feldmeier, Hermann

    2014-10-01

    Pediculosis capitis is the most common ectoparasitic disease in children in industrialized countries and extremely common in resource-poor communities of the developing world. The extensive use of pediculicides with a neurotoxic mode of action has led to the development and spread of resistant head lice populations all over the world. This triggered the development of compounds with other modes of action. The current literature on treatment approaches of head lice infestation was searched, and published randomized controlled trials were critically analyzed. The following compounds/family of compounds were identified: spinosad, a novel compound with a new neurotoxic mode of action, isopropyl myristate, 1,2-octanediol, ivermectin, plant-based products, and dimeticones. The efficacy and safety of these compounds are reviewed and recommendations for the treatment of pediculosis capitis in individuals as well as the interruption of ongoing epidemics are provided.

  16. Hypertrophic pachymeningitis: Current criteria for diagnosis and differentiation (Clinical case and review of literature

    Directory of Open Access Journals (Sweden)

    E. G. Mendelevich

    2015-01-01

    Full Text Available The paper describes a 44-year-old male patient with an about 6-year history of hypertrophic pachymeningitis. The major clinical symptoms were characterized by headache, exophthalmos, and blindness in one eye. The data for differential diagnosis of the disease are given. The current literature on the clinical manifestations of hypertrophic pachymeningitis, its differential diagnosis, and the results of magnetic resonance imaging (MRI is reviewed. Diagnostic difficulties at the stage of a clinical observation are due to the nonspecificity of neurological manifestations and the need for a comprehensive examination to detect a somatic disease. MRI can diagnose the disease-specific phenomenon of damage to the meninges, which calls for further careful differentiation. Clinicians must be familiar with alternative differential diagnosis, as a rapid specific therapeutic approach will help avoid long-term or irreversible neurological complications.

  17. Toward an Understanding of the Environmental and Public Health Impacts of Unconventional Natural Gas Development: A Categorical Assessment of the Peer-Reviewed Scientific Literature, 2009-2015.

    Science.gov (United States)

    Hays, Jake; Shonkoff, Seth B C

    2016-01-01

    The body of science evaluating the potential impacts of unconventional natural gas development (UNGD) has grown significantly in recent years, although many data gaps remain. Still, a broad empirical understanding of the impacts is beginning to emerge amidst a swell of research. The present categorical assessment provides an overview of the peer-reviewed scientific literature from 2009-2015 as it relates to the potential impacts of UNGD on public health, water quality, and air quality. We have categorized all available original research during this time period in an attempt to understand the weight and direction of the scientific literature. Our results indicate that at least 685 papers have been published in peer-reviewed scientific journals that are relevant to assessing the impacts of UNGD. 84% of public health studies contain findings that indicate public health hazards, elevated risks, or adverse health outcomes; 69% of water quality studies contain findings that indicate potential, positive association, or actual incidence of water contamination; and 87% of air quality studies contain findings that indicate elevated air pollutant emissions and/or atmospheric concentrations. This paper demonstrates that the weight of the findings in the scientific literature indicates hazards and elevated risks to human health as well as possible adverse health outcomes associated with UNGD. There are limitations to this type of assessment and it is only intended to provide a snapshot of the scientific knowledge based on the available literature. However, this work can be used to identify themes that lie in or across studies, to prioritize future research, and to provide an empirical foundation for policy decisions.

  18. Scientific information and the Tongass land management plan: key findings derived from the scientific literature, species assessments, resource analyses, workshops, and risk assessment panels.

    Science.gov (United States)

    Douglas N. Swanston; Charles G. Shaw; Winston P. Smith; Kent R. Julin; Guy A. Cellier; Fred H. Everest

    1996-01-01

    This document highlights key items of information obtained from the published literature and from specific assessments, workshops, resource analyses, and various risk assessment panels conducted as part of the Tongass land management planning process. None of this information dictates any particular decision; however, it is important to consider during decisionmaking...

  19. An Investigation of the Variety and Complexity of Statistical Methods Used in Current Internal Medicine Literature.

    Science.gov (United States)

    Narayanan, Roshni; Nugent, Rebecca; Nugent, Kenneth

    2015-10-01

    Accreditation Council for Graduate Medical Education guidelines require internal medicine residents to develop skills in the interpretation of medical literature and to understand the principles of research. A necessary component is the ability to understand the statistical methods used and their results, material that is not an in-depth focus of most medical school curricula and residency programs. Given the breadth and depth of the current medical literature and an increasing emphasis on complex, sophisticated statistical analyses, the statistical foundation and education necessary for residents are uncertain. We reviewed the statistical methods and terms used in 49 articles discussed at the journal club in the Department of Internal Medicine residency program at Texas Tech University between January 1, 2013 and June 30, 2013. We collected information on the study type and on the statistical methods used for summarizing and comparing samples, determining the relations between independent variables and dependent variables, and estimating models. We then identified the typical statistics education level at which each term or method is learned. A total of 14 articles came from the Journal of the American Medical Association Internal Medicine, 11 from the New England Journal of Medicine, 6 from the Annals of Internal Medicine, 5 from the Journal of the American Medical Association, and 13 from other journals. Twenty reported randomized controlled trials. Summary statistics included mean values (39 articles), category counts (38), and medians (28). Group comparisons were based on t tests (14 articles), χ2 tests (21), and nonparametric ranking tests (10). The relations between dependent and independent variables were analyzed with simple regression (6 articles), multivariate regression (11), and logistic regression (8). Nine studies reported odds ratios with 95% confidence intervals, and seven analyzed test performance using sensitivity and specificity calculations

  20. Patient knowledge, perceptions, and acceptance of generic medicines: a comprehensive review of the current literature

    Directory of Open Access Journals (Sweden)

    Alrasheedy AA

    2014-04-01

    Full Text Available Alian A Alrasheedy,1 Mohamed Azmi Hassali,1 Kay Stewart,2 David CM Kong,2 Hisham Aljadhey,3 Mohamed Izham Mohamed Ibrahim,4 Saleh Karamah Al-Tamimi1 1Discipline of Social and Administrative Pharmacy, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, Malaysia; 2Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Melbourne, VIC, Australia; 3Medication Safety Research Chair, Clinical Pharmacy Department, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia; 4College of Pharmacy, Qatar University, Doha, Qatar Background: Generic medicines have the same quality, safety, and efficacy as their counterpart original brand medicines. Generic medicines provide the same therapeutic outcomes but at a much cheaper cost, so are promoted in many countries to contain pharmaceutical expenditure and sustain the health care system. Thus, the perspective of patients and medicine consumers as end users of these medicines is an important factor to enhance the use and utilization of generic medicines. The objective of this paper is to review patients’ and consumers’ knowledge, perceptions, acceptance, and views of generic medicines in the current literature. Methods: An extensive literature search was performed in several databases, namely Scopus, PubMed, ISI Web of Knowledge, Proquest, and the Wiley online library, to identify relevant studies published in the English literature for the period 1990–2013. Results: A total of 53 studies were included in the review, comprising 24 studies from Europe, ten from North America, six from Asia, five from Australia and New Zealand, five from the Middle East, one from Africa, one from Latin America, and one from the Caribbean region. A large body of literature has reported misconceptions and negative perceptions about generic medicines on the part of patients and medicine consumers. Moreover, although it is reported in almost all countries, the percentage of consumers who had

  1. Intercultural Communicative Competence: A Brief Review of Current Thinking and Literature

    Directory of Open Access Journals (Sweden)

    Masoud Kermani Kojour

    2016-12-01

    Full Text Available The present study aims to review current thinking and understanding of the issue of Intercultural Communicative Competence (ICC especially in foreign language education contexts. There are serious stances on the part of scholars in foreign language contexts, which must be given some serious thinking and consideration in order to uncover the hidden agendas regarding ICC. After all, it seems still unclear in English as a Foreign Language (EFL contexts whether to try to improve the way of thinking regarding the perspective of current intercultural communicative competence, whether there should be a separation of the cultural values from the target language and only integrate language learners’ native culture with the target language. Given the development of technology and globalization, what is the right thing to do? This is a serious issue which needs much attention and contemplation by the interested scholars. By presenting the existing gaps in the literature, the paper maneuvers on the challenging notes on benefiting from culture in English Language Teaching (ELT and, on the other hand, dividing language and culture by merely elaborating on the communicative aspect of language learning and teaching. The study puts the audience into question that although recent views are focusing on taking English as an international means of communication, there exist serious beliefs regarding the separation of language and culture, which demands more thinking and probably serious revisions.

  2. Terminology and reporting criteria for radiofrequency ablation of tumors in the scientific literature: Systematic review of compliance with reporting standards

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Tae Wook; Rhim, Hyun Chul; Lee, Min Woo; Kim, Young Sun; Choi, Dongil; Lim, Hyo Keun [Dept. of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul (Korea, Republic of)

    2014-02-15

    To perform a systematic review of compliance with standardized terminology and reporting criteria for radiofrequency (RF) tumor ablation, proposed by the International Working Group on Image-Guided Tumor Ablation in 2003, in the published reports. Literature search in the PubMed database was performed using index keywords, PubMed limit system, and eligibility criteria. The entire content of each article was reviewed to assess the terminology used for procedure terms, imaging findings, therapeutic efficacy, follow-up, and complications. Accuracy of the terminology and the use of alternative terms instead of standard terminology were analyzed. In addition, disparities in accuracy of terminology in articles according to the medical specialty and the type of radiology journal were evaluated. Among the articles (n = 308) included in this study, the accuracy of the terms 'procedure or session', 'treatment', 'index tumor', 'ablation zone', 'technical success', 'primary technique effectiveness rate', 'secondary technique effectiveness rate', 'local tumor progression', 'major complication', and 'minor complication' was 97% (298/307), 97% (291/300), 8% (25/307), 65% (103/159), 55% (52/94), 33% (42/129), 94% (17/18), 45% (88/195), 99% (79/80), and 100% (77/77), respectively. The overall accuracy of each term showed a tendency to improve over the years. The most commonly used alternative terms for 'technical success' and 'local tumor progression' were 'complete ablation' and 'local (tumor) recurrence', respectively. The accuracy of terminology in articles published in radiology journals was significantly greater than that of terminology in articles published in non-radiology journals, especially in Radiology and The Journal of Vascular and Interventional Radiology. The proposal for standardization of terminology and reporting criteria for

  3. A writing-intensive course improves biology undergraduates' perception and confidence of their abilities to read scientific literature and communicate science.

    Science.gov (United States)

    Brownell, Sara E; Price, Jordan V; Steinman, Lawrence

    2013-03-01

    Most scientists agree that comprehension of primary scientific papers and communication of scientific concepts are two of the most important skills that we can teach, but few undergraduate biology courses make these explicit course goals. We designed an undergraduate neuroimmunology course that uses a writing-intensive format. Using a mixture of primary literature, writing assignments directed toward a layperson and scientist audience, and in-class discussions, we aimed to improve the ability of students to 1) comprehend primary scientific papers, 2) communicate science to a scientific audience, and 3) communicate science to a layperson audience. We offered the course for three consecutive years and evaluated its impact on student perception and confidence using a combination of pre- and postcourse survey questions and coded open-ended responses. Students showed gains in both the perception of their understanding of primary scientific papers and of their abilities to communicate science to scientific and layperson audiences. These results indicate that this unique format can teach both communication skills and basic science to undergraduate biology students. We urge others to adopt a similar format for undergraduate biology courses to teach process skills in addition to content, thus broadening and strengthening the impact of undergraduate courses.

  4. Trigger factors of cutaneous lupus erythematosus: a review of current literature.

    Science.gov (United States)

    Szczęch, J; Samotij, D; Werth, V P; Reich, A

    2017-01-01

    It is currently believed that autoimmune conditions are triggered and aggravated by a variety of environmental factors such as cigarette smoking, infections, ultraviolet light or chemicals, as well as certain medications and vaccines in genetically susceptible individuals. Recent scientific data have suggested a relevant role of these factors not only in systemic lupus erythematosus, but also in cutaneous lupus erythematosus (CLE). A variety of environmental factors have been proposed as initiators and exacerbators of this disease. In this review we focused on those with the most convincing evidence, emphasizing the role of drugs in CLE. Using a combined search strategy of the MEDLINE and CINAHL databases the following trigger factors and/or exacerbators of CLE have been identified and described: drugs, smoking, neoplasms, ultraviolet radiation and radiotherapy. In order to give a practical insight we emphasized the role of drugs from various groups and classes in CLE. We also aimed to present a short clinical profile of patients with lesions induced by various drug classes.

  5. A critical overview of the current myofascial pain literature - October 2015.

    Science.gov (United States)

    Dommerholt, Jan; Grieve, Rob; Hooks, Todd; Layton, Michelle

    2015-10-01

    The number of publications about myofascial pain and trigger points (TrP) seems to increase every year. In the current overview we include 27 articles published in past months. The Basic Review section includes articles about the presence and characteristics of TrPs in various neck and shoulder muscles, the correlation between referred pain from active TrPs and knee osteoarthritis, and an anatomical study exploring whether the location of TrPs may be related to the nerve innervation of muscles. Zuil-Escobar and colleagues from Spain considered the intra-rater reliability of the identification of latent TrPs in several leg muscles and the possible correlation of TrP and the presence of a lower medial longitudinal arch. In the section on manual approaches, contributing author Rob Grieve and colleagues continue their studies of TrPs in the lower extremity muscles, while Méndez-Rebolledo and colleagues studied the impact of cross taping and compression. Dry needling (DN) continues to be a topic of interest. We included twelve papers addressing a wide range of topics, such as the effectiveness and safety of DN, and the impact of DN on proprioception, spasticity, and fibromyalgia. Two papers investigated the utilization of repetitive transcranial magnetic stimulation and laser on TrPs, The final section on other clinical studies and reviews includes 8 papers. The studies originated in thirteen different countries with Spain leading the charts with 7 contributions to the literature, followed by Brazil with four. As we have mentioned in previous editions of this literature overview, many studies suffer from very small sample sizes, which makes it difficult to reach definitive conclusions. Nevertheless, myofascial pain continues to be a topic of interest to researchers and clinicians around the globe. Copyright © 2015 Elsevier Ltd. All rights reserved.

  6. Guidelines for the Design and Conduct of Clinical Studies in Knee Articular Cartilage Repair: International Cartilage Repair Society Recommendations Based on Current Scientific Evidence and Standards of Clinical Care.

    Science.gov (United States)

    Mithoefer, Kai; Saris, Daniel B F; Farr, Jack; Kon, Elizaveta; Zaslav, Kenneth; Cole, Brian J; Ranstam, Jonas; Yao, Jian; Shive, Matthew; Levine, David; Dalemans, Wilfried; Brittberg, Mats

    2011-04-01

    To summarize current clinical research practice and develop methodological standards for objective scientific evaluation of knee cartilage repair procedures and products. A comprehensive literature review was performed of high-level original studies providing information relevant for the design of clinical studies on articular cartilage repair in the knee. Analysis of cartilage repair publications and synopses of ongoing trials were used to identify important criteria for the design, reporting, and interpretation of studies in this field. Current literature reflects the methodological limitations of the scientific evidence available for articular cartilage repair. However, clinical trial databases of ongoing trials document a trend suggesting improved study designs and clinical evaluation methodology. Based on the current scientific information and standards of clinical care, detailed methodological recommendations were developed for the statistical study design, patient recruitment, control group considerations, study endpoint definition, documentation of results, use of validated patient-reported outcome instruments, and inclusion and exclusion criteria for the design and conduct of scientifically sound cartilage repair study protocols. A consensus statement among the International Cartilage Repair Society (ICRS) and contributing authors experienced in clinical trial design and implementation was achieved. High-quality clinical research methodology is critical for the optimal evaluation of current and new cartilage repair technologies. In addition to generally applicable principles for orthopedic study design, specific criteria and considerations apply to cartilage repair studies. Systematic application of these criteria and considerations can facilitate study designs that are scientifically rigorous, ethical, practical, and appropriate for the question(s) being addressed in any given cartilage repair research project.

  7. Potential disease transmission from wild geese and swans to livestock, poultry and humans : a review of the scientific literature from a One Health perspective

    OpenAIRE

    Elmberg, Johan; Berg, Charlotte; Lerner, Henrik; Waldenström, Jonas; Hessel, Rebecca

    2017-01-01

    ABSTRACT There are more herbivorous waterfowl (swans and geese) close to humans, livestock and poultry than ever before. This creates widespread conflict with agriculture and other human interests, but also debate about the role of swans and geese as potential vectors of disease of relevance for human and animal health. Using a One Health perspective, we provide the first comprehensive review of the scientific literature about the most relevant viral, bacterial, and unicellular pathogens occu...

  8. Deep brain stimulation for Parkinson disease in Australia: current scientific and clinical status.

    Science.gov (United States)

    Poortvliet, P C; Silburn, P A; Coyne, T J; Chenery, H J

    2015-02-01

    There is currently no cure for Parkinson disease (PD). Disease management is directed primarily at motor symptom relief, but the impact of non-motor symptoms associated with PD should not be underestimated. Medical and surgical treatment options aim to increase functional independence and quality of life. Deep brain stimulation (DBS) has proven to be a safe, effective and cost-efficient surgical treatment option. In 2009, the Australian referral guidelines, developed to provide a synopsis of DBS therapy for PD, were introduced, and since then novel findings have been reported regarding the timing of intervention, target selection and symptom management. Our aim is to provide an update of DBS for PD in Australia. Intervention at earlier stages of the disease can potentially improve quality of life over a longer period with greater possibilities for meaningful social and professional contributions. For less responsive motor symptoms (e.g. freezing of gait, postural instability), the pedunculopontine nucleus has emerged as a promising new surgical target. Traditional PD treatment is focused on improvement of motor symptoms, but the disorder is also characterised by non-motor symptoms, often undiagnosed or undisclosed, that have the potential to impact quality of life to a greater extent than motor symptoms. It is essential to identify and routinely monitor for non-motor symptoms as they can emerge at all stages of the disease or can result from treatment. Many of these current advances require long-term monitoring of treatment outcomes to improve future clinical practice, refine patient selection and ensure best patient outcomes.

  9. Trends in scientific literature on addiction to the internet, video games, and cell phones from 2006 to 2010

    Directory of Open Access Journals (Sweden)

    Xavier Carbonell

    2016-01-01

    Conclusions: The number of publications on technological addictions reached a peak in 2008. The scientific contributions of China, Taiwan, and Korea are overrepresented compared to other scientific fields such as drug addiction. The inclusion of Internet Gaming Disorder in the Diagnostic and Statistical Manual of Mental Disorders, 5 th Edition could change the publication trends in the technological addiction area and underline the relevance of this upcoming disorder in dissatisfaction with life in general.

  10. [The history of Mindfulness put to the test of current scientific data: unresolved questions].

    Science.gov (United States)

    Trousselard, M; Steiler, D; Claverie, D; Canini, F

    2014-12-01

    The first part of this paper describes the long history of the concept of Mindfulness. Contrary to the belief that Mindfulness only has Buddhist and Hindu origins, it is also rooted in Jewish, Islamic and Christian religions. Furthermore, western philosophers have described a mindful path to become more aware of thoughts, feelings, and bodily sensations. Mindfulness can be considered as a universal human ability embodied to foster clear thinking and open-heartedness. As such, this form of being requires no particular religious or cultural belief system. The current acceptance of what a mindful path is, refers to a psychological quality that involves bringing one's complete attention to present experience on a moment-to-moment basis, in a particular way: in the present moment, and nonjudgmentally. Although such a definition is well accepted in France, the French translation for Mindfulness is not easy to use: being conscious and being aware are translated with the same French word. The French language fails to clearly separate the dimensional attributes of a mindful subject from the ways for developing mindfulness through formal meditation practice. In line with this conception, stability and assessments of Mindfulness mainly were examined. How this disposition allows the development of concentration, attention and acceptance moment by moment in a nonjudgmental way is described in the second part. Particular attention is paid to its positive effects in several aspects of mental and physical health. In particular, positive effects on the ability to cope with stress are described from a physiological point of view. Third, this article intends to present neurobiological aspects currently proposed to explain the benefits of Mindfulness meditation. Modifications of cerebral networks and neurobiological functioning are described in relation to expertise in meditation practice. The hypothesis of the role of meditation on neuroplasticity is also discussed. Furthermore, the

  11. Current role of rufinamide in the treatment of childhood epilepsy: literature review and treatment guidelines.

    Science.gov (United States)

    Coppola, Giangennaro; Besag, Frank; Cusmai, Raffaella; Dulac, Olivier; Kluger, Gerhard; Moavero, Romina; Nabbout, Rima; Nikanorova, Marina; Pisani, Francesco; Verrotti, Alberto; von Stülpnagel, Celina; Curatolo, Paolo

    2014-11-01

    The literature on the efficacy and safety of rufinamide in childhood-onset epilepsy syndromes currently includes approximately 600 paediatric patients. This paper summarizes the views of a panel of experienced European epileptologists with regard to the current role of rufinamide in the treatment of childhood epilepsies. Rufinamide is effective in decreasing the seizure frequency in the Lennox-Gastaut syndrome (LGS), especially tonic and atonic seizures. It might consequently be preferred to other drugs as a second-line treatment for LGS when drop-attacks are frequent. The mean responder rate in the published studies is 38% with seizure freedom achieved in 2.4% of patients. Rufinamide has shown some efficacy in epileptic encephalopathies other than LGS. It can be also effective as adjunctive therapy in children and adolescents with drug-resistant partial seizures. The available data suggest that rufinamide has an acceptable risk/benefit ratio with quite a low risk of aggravating seizures. Common adverse effects (somnolence, nausea and vomiting) are usually mild and self-limiting; they are more frequently observed during titration than in the maintenance phase, suggesting that low escalation rates might be associated with fewer adverse effects. Rufinamide appears to have a favourable cognitive profile compared with other antiepileptic drugs. Rufinamide is only approved for adjunctive treatment of seizures associated with LGS in children 4 years of age and older. There are very few data on rufinamide treatment at the onset of LGS or early in the course of the disorder; whether early treatment will improve outcome has yet to be determined. Copyright © 2014 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved.

  12. Efficacy, safety, acceptability and affordability of cryotherapy: a review of current literature.

    Science.gov (United States)

    McClung, E C; Blumenthal, P D

    2012-04-01

    As a result of widespread screening and treatment programs, the incidence of cervical cancer has decreased by as much as 75% in the developed world. Commonly used treatment modalities for precancerous lesions include cone biopsy, the Loop Electrosurgical Excision Procedure (LEEP), laser ablation and cryotherapy. In recent years LEEP has replaced cryotherapy as a commonly provided outpatient procedure in many places; however increased awareness of the burden of cervical cancer in the developing world and increased awareness of long term consequences of LEEP ‑ such as cervical insufficiency ‑ have renewed interest in cryotherapy. We reviewed current literature addressing the technique, efficacy, safety and acceptability of cryotherapy, as well as special topics such as cost effectiveness, HIV, and low resource settings. Among studies we reviewed, cure rates ranged from 56.8-96.6% among prospective controlled trials and from 70-95.5% among observational studies. Cryotherapy has very low complication rates and serious complications requiring medical intervention or affecting future reproductive outcomes are extremely rare. Side effects including vaginal discharge and cramping are temporary, generally self-limited, and well tolerated after anticipatory patient counseling. When surveyed, women find cryotherapy highly acceptable. Compared to other treatment modalities, cryotherapy is very affordable and feasible to integrate into cervical cancer screening and treatment programs.

  13. Enhanced depth imaging-OCT of the choroid: a review of the current literature.

    Science.gov (United States)

    Laviers, H; Zambarakji, H

    2014-12-01

    With the advent of enhanced depth imaging optical coherence tomography (EDI-OCT), detailed visualisation of the choroid in vivo is now possible. Measurements of choroidal thickness (CT) have also enabled new directions in research to study normal and pathological processes within the choroid. The aim of the present study is to review the current literature on choroidal imaging using EDI-OCT. Studies were identified by a systematic search using Medline ( http://www.ncbi.nlm.nih.gov/pubmed ). Papers were also identified based on the reference lists of relevant publications. Papers were included in the review if the focus of the study involved imaging of the choroid using EDI-OCT. Recent studies have demonstrated successful imaging of the choroid and high reproducibility of measurements of CT using EDI-OCT. There are much data confirming that abnormalities in choroidal structure and function contribute to major ocular diseases and patterns of CT variation may be observed in certain disease states and may be influenced by treatment. However, it is not clear whether these variations are a contributing factor or a consequence of the disease. While more invasive methods such as indocyanine green (ICG) angiography remain the gold standard for detecting abnormalities of the choroidal vasculature in normal eyes and disease states, EDI-OCT has become an important adjunctive clinical tool in providing three-dimensional anatomical information of the choroid.

  14. Rapid Collaborative Scientific and Technical Literature Push Mechanism Based on Intelligent Agent%一种基于智能Agent的科技文献快速协作推送机制

    Institute of Scientific and Technical Information of China (English)

    徐小龙; 赵昌耀; 耿卫健; 程春玲

    2011-01-01

    The current scientific and technical literature network-sharing platforms have a mass of papers, which is difficult for users to get what they really need. We presented a new Rapid collaborative scientific and technical literature push model based on intelligent Agent. This model adopts Intelligent Agent technology to build the User Agent, Data Transfer Agent, Information Evaluation Agent, Information Analysis Agent, Server Monitor Agent and Data Mining Agent, to establish an effective collaborative relationship between clients and servers, provide scientific and technical literatures jointly for each users meeting their needs perfectly. We also proposed a Literature-Readers Matching Assessment Algorithm(LRMAA) ,which is to comprehensively consider the subscription information provided by user initiatively,the user's reading history, the objective assessment of literature as well as the literature publishing time, to get the matching vector, resulting in a true and accurate access to the user's research interests and focuses in time to provide users with the most valuable, suitable and high-quality scientific and technical literature information. This paper first analyzed the current network Information Pull and Push methods, and then introduced the Intelligent Agent-based rapid collaborative scientific and technical literature push model, at last, discussed LRMAA in detail about all parameters computing of the vector.%针对目前网络科技文献共享平台上汇聚的海量的科技文献,提出了一种新的基于智能Agent的科技文献快速协作推送模型,通过引入由智能Agent技术构建的用户Agent、数据传递Agent、信息评估Agent、信息分析Agent、服务器监控Agent和数据挖掘Agent,在客户机和服务器之间建立一种有效的协作关系,联合为每个用户主动提供最符合其需求的科技文献.提出了一种新的文献一读者契合度评估算法,算法综合考虑用户主动提供的订阅信息、

  15. Dedifferentiated chondrosarcoma arising in fibrous dysplasia: A case report and review of the current literature

    Directory of Open Access Journals (Sweden)

    Nicole MD Riddle

    2009-06-01

    Full Text Available Nicole MD Riddle1, Hideko Yamauchi2, Jamie T Caracciolo4, David Johnson2, G Douglas Letson2, Ardeshir Hakam1,3, Prudence V Smith1,2,3, Marilyn M Bui1,2,31Department of Pathology and Cell Biology, University of South Florida, Tampa, FL, USA; 2Department of Sarcoma, 3Department of Anatomic Pathology, 4Department of Radiology, Moffitt Cancer Center, Tampa, FL, USABackground: Fibrous dysplasia is an uncommon bone disease that has rare but clear potential for malignant transformation. The frequency is increased in polyostotic forms, McCune–Albright syndrome, Mazabraud’s syndrome, and previously irradiated sites. Rapidly progressing pain unrelated to trauma is the most concerning symptom. The early radiological features of sarcomatous transformation are moth-eaten or cystic areas of osteolysis, cortical destruction, and gradual formation of a soft tissue mass. The prognosis is unfavorable as most of the cases are in an advanced stage at the time of diagnosis.Methods: This case was diagnosed at a large cancer center in Florida. Pertinent clinical findings were obtained from chart review and inter-departmental consultation.Results: Histopathological examination revealed dysplastic lamellar bone with no osteoblastic rimming and “Chinese letter” shapes, areas composed of lobulated hyaline cartilage with mild to severe nuclear atypia, and areas of poorly differentiated cells with a spindled appearance, consistent with chondrosarcoma arising within fibrous dysplasia.Conclusions: Sarcomatous transformation of fibrous dysplasia is an uncommon occurrence, yet has significant importance for those with the disease. There may be difficulty with diagnosis given the symptoms and radiologic findings of benign fibrous dysplasia. We report a case of chondrosarcoma rising in fibrous dysplasia and review the current literature. This case is of interest due to the fact that the diagnosis of monostotic fibrous dysplasia was first made at the age of 59 and

  16. Diversity Management Interventions and Organizational Performance: A Synthesis of Current Literature

    Science.gov (United States)

    Curtis, Ellen Foster; Dreachslin, Janice L.

    2008-01-01

    Despite the growing body of literature focused on diversity management and its implications for career experiences and perceptions, team dynamics, customer service, and other dimensions of organizational performance, a significant gap remains. To address the gap, this article reviews the managing diversity literature published between January 2000…

  17. Social Work Literature Searching: Current Issues with Databases and Online Search Engines

    Science.gov (United States)

    McGinn, Tony; Taylor, Brian; McColgan, Mary; McQuilkan, Janice

    2016-01-01

    Objectives: To compare the performance of a range of search facilities; and to illustrate the execution of a comprehensive literature search for qualitative evidence in social work. Context: Developments in literature search methods and comparisons of search facilities help facilitate access to the best available evidence for social workers.…

  18. Vaccinations in migrants and refugees: a challenge for European health systems. A systematic review of current scientific evidence.

    Science.gov (United States)

    Mipatrini, Daniele; Stefanelli, Paola; Severoni, Santino; Rezza, Giovanni

    2017-03-01

    The decline of immunization rates in countries of origin of migrants and refugees, along with risky conditions during the journey to Europe, may threaten migrants' health. We performed a systematic review of the scientific literature in order to assess the frequency of vaccine preventable diseases, and vaccination coverage among migrants and refugees in Europe. To this end, Medline and Cochrane databases were considered. After the screening and the selection process, 58 papers were included in the review. We focused on the following vaccine-preventable diseases: hepatitis B, measles, rubella, mumps, tetanus, poliomyelitis, pertussis, diphtheria, meningitis, and varicella. The results were presented as a qualitative synthesis. In summary, several studies highlighted that migrants and refugees have lower immunization rates compared to European-born individuals. Firstly, this is due to low vaccination coverage in the country of origin. Then, several problems may limit migrants' access to vaccination in Europe: (i) migrants are used to move around the continent, and many vaccines require multiple doses at regular times; (ii) information on the immunization status of migrants is often lacking; (iii) hosting countries face severe economic crises; (iv) migrants often refuse registration with medical authorities for fear of legal consequences and (v) the lack of coordination among public health authorities of neighboring countries may determine either duplications or lack of vaccine administration. Possible strategies to overcome these problems include tailoring immunization services on the specific needs of the target population, developing strong communication campaigns, developing vaccination registers, and promoting collaboration among public health authorities of European Countries.

  19. Teaching toward a More Scientifically Literate Society

    Science.gov (United States)

    LoGiudici, Raymond; Ende, Fred

    2010-01-01

    To teach scientific literacy to eighth graders, the authors created a yearlong project that emphasizes the various components and skills required to be a scientifically literate citizen. This project is broken into four separate components: skeptical thinking (pseudoscience), current-event article analysis, fiction and nonfiction literature, and…

  20. Radiology Physician Extenders: A Literature Review of the History and Current Roles of Physician Extenders in Medical Imaging.

    Science.gov (United States)

    Sanders, Vicki L; Flanagan, Jennifer

    2015-01-01

    The purpose of the literature review was to assess the origins of radiology physician extenders and examine the current roles found in the literature of advanced practice physician extenders within medical imaging. Twenty-six articles relating to physician assistants (PAs), nurse practitioners (NPs), radiologist assistants (RAs), and nuclear medicine advanced associates (NMAAs) were reviewed to discern similarities and differences in history, scope of practice, and roles in the medical imaging field. The literature showed PAs and NPs are working mostly in interventional radiology. PAs, NPs, and RAs perform similar tasks in radiology, including history and physicals, evaluation and management, preprocedure work-up, obtaining informed consent, initial observations/reports, and post-procedure follow-up. NPs and PAs perform a variety of procedures but most commonly vascular access, paracentesis, and thoracentesis. RAs perform gastrointestinal, genitourinary, nonvascular invasive fluoroscopy procedures, and vascular access procedures. The review revealed NMAAs are working in an advanced role, but no specific performances of procedures was found in the literature, only suggested tasks and clinical competencies. PAs, NPs, and RAs are currently the three main midlevel providers used in medical imaging. These midlevel providers are being used in a variety of ways to increase the efficiency of the radiologist and provide diagnostic and therapeutic radiologic procedures to patients. NMAAs are being used in medical imaging but little literature is available on current roles in clinical practice. More research is needed to assess the exact procedures and duties being performed by these medical imaging physician extenders.

  1. Current Understanding of Non-Diabetic Ketoacidosis Development in Children. Part 2 (Analytic Review of Literature

    Directory of Open Access Journals (Sweden)

    L.V. Pypa

    2015-11-01

    Full Text Available Analytic review of the literature regarding the terminology, clinical manifestations, modern principles of treatment of non-diabetic ketoacidosis in children was conducted in the article.

  2. Current Understanding of Non-Diabetic Ketoacidosis in Children. Part 1 (Analytic Review of the Literature

    Directory of Open Access Journals (Sweden)

    L.V. Pypa

    2015-07-01

    Full Text Available Analytic review of the literature regarding the mechanisms of non-diabetic ketoacidosis in children, particularly on the background of acute intestinal infections, has been carried out in the article.

  3. A critical overview of the current myofascial pain literature - July 2016.

    Science.gov (United States)

    Dommerholt, Jan; Grieve, Rob; Finnegan, Michelle; Hooks, Todd

    2016-07-01

    The overview of the myofascial pain literature includes a wide variety of basic and clinical studies, ranging from assessing muscle activation patterns to the impact of platelet-rich plasma injections. Contributions to the literature once again came from all corners of the world, such as Australia, Belgium, Brazil, Germany, Greece, Iran, Italy, Japan, Korea, the Netherlands, Norway, Poland, Spain, Taiwan, Turkey, and the USA. A total of 30 papers are included in this overview.

  4. Types and severity of medication errors in Iran; a review of the current literature.

    Science.gov (United States)

    Mansouri, Ava; Ahmadvand, Alireza; Hadjibabaie, Molouk; Kargar, Mona; Javadi, Mohammadreza; Gholami, Kheirollah

    2013-06-20

    Medication error (ME) is the most common single preventable cause of adverse drug events which negatively affects patient safety. ME prevalence is a valuable safety indicator in healthcare system. Inadequate studies on ME, shortage of high-quality studies and wide variations in estimations from developing countries including Iran, decreases the reliability of ME evaluations. In order to clarify the status of MEs, we aimed to review current available literature on this subject from Iran. We searched Scopus, Web of Science, PubMed, CINAHL, EBSCOHOST and also Persian databases (IranMedex, and SID) up to October 2012 to find studies on adults and children about prescription, transcription, dispensing, and administration errors. Two authors independently selected and one of them reviewed and extracted data for types, definitions and severity of MEs. The results were classified based on different stages of drug delivery process. Eighteen articles (11 Persian and 7 English) were included in our review. All study designs were cross-sectional and conducted in hospital settings. Nursing staff and students were the most frequent populations under observation (12 studies; 66.7%). Most of studies did not report the overall frequency of MEs aside from ME types. Most of studies (15; 83.3%) reported prevalence of administration errors between 14.3%-70.0%. Prescribing error prevalence ranged from 29.8%-47.8%. The prevalence of dispensing and transcribing errors were from 11.3%-33.6% and 10.0%-51.8% respectively. We did not find any follow up or repeated studies. Only three studies reported findings on severity of MEs. The most reported types of and the highest percentages for any type of ME in Iran were administration errors. Studying ME in Iran is a new area considering the duration and number of publications. Wide ranges of estimations for MEs in different stages may be because of the poor quality of studies with diversity in definitions, methods, and populations. For gaining

  5. Types and Severity of Medication Errors in Iran; a Review of the Current Literature

    Directory of Open Access Journals (Sweden)

    Ava Mansouri

    2013-06-01

    Full Text Available Medication error (ME is the most common single preventable cause of adverse drug events which negatively affects patient safety. ME prevalence is a valuable safety indicator in healthcare system. Inadequate studies on ME, shortage of high-quality studies and wide variations in estimations from developing countries including Iran, decreases the reliability of ME evaluations. In order to clarify the status of MEs, we aimed to review current available literature on this subject from Iran. We searched Scopus, Web of Science, PubMed, CINAHL, EBSCOHOST and also Persian databases (IranMedex, and SID up to October 2012 to find studies on adults and children about prescription, transcription, dispensing, and administration errors. Two authors independently selected and one of them reviewed and extracted data for types, definitions and severity of MEs. The results were classified based on different stages of drug delivery process. Eighteen articles (11 Persian and 7 English were included in our review. All study designs were cross-sectional and conducted in hospital settings. Nursing staff and students were the most frequent populations under observation (12 studies; 66.7%. Most of studies did not report the overall frequency of MEs aside from ME types. Most of studies (15; 83.3% reported prevalence of administration errors between 14.3%-70.0%. Prescribing error prevalence ranged from 29.8%-47.8%. The prevalence of dispensing and transcribing errors were from 11.3%-33.6% and 10.0%-51.8% respectively. We did not find any follow up or repeated studies. Only three studies reported findings on severity of MEs. The most reported types of and the highest percentages for any type of ME in Iran were administration errors. Studying ME in Iran is a new area considering the duration and number of publications. Wide ranges of estimations for MEs in different stages may be because of the poor quality of studies with diversity in definitions, methods, and populations

  6. Mining Learning and Crafting Scientific Experiments: A Literature Review on the Use of Minecraft in Education and Research

    Science.gov (United States)

    Nebel, Steve; Schneider, Sascha; Rey, Günter Daniel

    2016-01-01

    Since the field of educational videogames or serious games is not limited to games that are specifically designed for educational purposes, videogames such as Minecraft have aroused the attention of teachers and researchers alike. To gain insights into the applicability of Minecraft, we reviewed the literature on use of the game in education and…

  7. On Training of Scientific Literature Education to the Scientific Literacy of Young Children%论科学文艺教育对幼儿科学素质的培养

    Institute of Scientific and Technical Information of China (English)

    于敏

    2014-01-01

    Since the reform and opening up, under the influence of"education"strategy and the"Science education should start with children"under the slogan of the past twenty years time, science education has become the new darling of nursery education. The scientific quality of foster children became the slogan of many of the media, has become the choice of many parents. The scien-tific literature in which its unique charm is attracting young children, science and arts education to enhance the scientific quality of foster children has an important role, is an important way to promote the scientific development of children.%改革开放以来,在“科教兴国”战略的影响下以及“科学教育要从娃娃抓起”口号下,短短二十几年的时间,科学教育成为幼儿园教育的新宠。培养幼儿的科学素质成为了众多媒体的口号,也成为了众多家长的选择。而在这其中科学文艺以其独特的魅力正吸引着年幼的孩子,科学文艺教育对幼儿科学素质的提升与培养具有重要的作用,是促进幼儿科学素质养成的重要方式。

  8. Navigating the Role of Business Incubators: A Review on the Current Literature on Business Incubation in South Africa

    Directory of Open Access Journals (Sweden)

    Thobekani Lose

    2016-10-01

    Full Text Available Business incubators (BIs are a significant tool in promoting the development of entrepreneurial firms, technology-based growth firms and economic growth in South Africa. The study reviewed the current literature on business incubation in South Africa. BIs in South Africa emerged as a popular strategy in the 1990s and most of the current literature was established in the same period. However, the current literature is still limited. The aim of this paper is to provide an overview of existing knowledge on the role and effectiveness of business incubation in supporting the development of new small startup businesses. The quantitative and qualitative literature published by the academic and practitioner communities is reviewed. The searches indicated that incubation has encouraged many studies in South Africa. The studies can be categorised under the following themes: the role and contribution of incubators, success factors for business incubation, obstacles, and the relationship between incubators and entrepreneurship. The areas for further research are suggested. Two major areas that new research can explore focus on the creation of the model and selfsustainability of BIs.

  9. The Biological Function and Clinical Utilization of CD147 in Human Diseases: A Review of the Current Scientific Literature

    Directory of Open Access Journals (Sweden)

    Lijuan Xiong

    2014-09-01

    Full Text Available CD147 or EMMPRIN is a member of the immunoglobulin superfamily in humans. It is widely expressed in human tumors and plays a central role in the progression of many cancers by stimulating the secretion of matrix metalloproteinases (MMPs and cytokines. CD147 regulates cell proliferation, apoptosis, and tumor cell migration, metastasis and differentiation, especially under hypoxic conditions. CD147 is also important to many organ systems. This review will provide a detailed overview of the discovery, characterization, molecular structure, diverse biological functions and regulatory mechanisms of CD147 in human physiological and pathological processes. In particular, recent studies have demonstrated the potential application of CD147 not only as a phenotypic marker of activated regulatory T cells but also as a potential diagnostic marker for early-stage disease. Moreover, CD147 is recognized as an effective therapeutic target for hepatocellular carcinoma (HCC and other cancers, and exciting clinical progress has been made in HCC treatment using CD147-directed monoclonal antibodies.

  10. The biological function and clinical utilization of CD147 in human diseases: a review of the current scientific literature.

    Science.gov (United States)

    Xiong, Lijuan; Edwards, Carl K; Zhou, Lijun

    2014-09-29

    CD147 or EMMPRIN is a member of the immunoglobulin superfamily in humans. It is widely expressed in human tumors and plays a central role in the progression of many cancers by stimulating the secretion of matrix metalloproteinases (MMPs) and cytokines. CD147 regulates cell proliferation, apoptosis, and tumor cell migration, metastasis and differentiation, especially under hypoxic conditions. CD147 is also important to many organ systems. This review will provide a detailed overview of the discovery, characterization, molecular structure, diverse biological functions and regulatory mechanisms of CD147 in human physiological and pathological processes. In particular, recent studies have demonstrated the potential application of CD147 not only as a phenotypic marker of activated regulatory T cells but also as a potential diagnostic marker for early-stage disease. Moreover, CD147 is recognized as an effective therapeutic target for hepatocellular carcinoma (HCC) and other cancers, and exciting clinical progress has been made in HCC treatment using CD147-directed monoclonal antibodies.

  11. Lumbar stabilization: a review of core concepts and current literature, part 2.

    Science.gov (United States)

    Barr, Karen P; Griggs, Miriam; Cadby, Todd

    2007-01-01

    Lumbar-stabilization exercise programs have become increasingly popular as a treatment for low-back pain. In this article, we outline an evidence-based medicine approach to evaluating patients for a lumbar-stabilization program. We also discuss typical clinical components of this type of program and the rationale for including these particular features based on the medical literature.

  12. ADHD, Substance Use Disorders, and Psychostimulant Treatment: Current Literature and Treatment Guidelines

    Science.gov (United States)

    Kollins, Scott H.

    2008-01-01

    Objective: This review explores the relationship between ADHD and substance use disorder (SUD), factors that determine the abuse potential of psychostimulants, and strategies for identifying and treating at-risk ADHD patients. Method: This study uses a Medline review of literature. Results: Psychostimulants, such as methylphenidate and…

  13. The Current Scope of Health Disparities in the U.S.: A Review of Literature

    Science.gov (United States)

    Pettit, Michele L.; Nienhaus, Alyson R.

    2010-01-01

    This review of literature examines leading contributors and mediators of health disparities in the United States. Specifically, poverty, education, and health are addressed. Special emphasis is placed on implications of health risk behaviors and health education for select populations and settings. Existing and suggested strategies for addressing…

  14. 我校体育教师科研现状分析与研究%Analysis and Research on the Current Situation of Physi-cal Education Teachers' Scientific Research in Our School

    Institute of Scientific and Technical Information of China (English)

    徐红琴

    2013-01-01

      选取我校13位专业教师的科研论文为研究对象,采用数据调查法、数理统计法及文献资料法等研究方法对我校体育教师科研现状进行分析研究,提出提高我校体育教师科研能力的有效途径。%In this article, 13 professional teachers' research pa-pers in our school were selected as the research object, we use research methods such as data survey method, mathematical statistics method and the literature method to research and ana-lyze the current situation of scientific research from the physical education teachers in our school, put forward the effective ways to improve our school physical education teachers' scientific re-search ability.

  15. Trends in Scientific Literature on Addiction to the Internet, Video Games, and Cell Phones from 2006 to 2010

    Science.gov (United States)

    Carbonell, Xavier; Guardiola, Elena; Fuster, Héctor; Gil, Frederic; Panova, Tayana

    2016-01-01

    Background: The goals of the present work were to retrieve the scientific articles published on addiction to the Internet, video games, and cell phones and to analyze the pattern of publications in this area (who is doing the research, when and where it is taking place, and in which journals it is being published), to determine the research being conducted as well as to document geographical trends in publication over time in three types of technological addictions: Internet, cell phones, and video games. Methods: Articles indexed in PubMed and PsycINFO between 2006 and 2010 related to the pathological use of Internet, cell phones, and video games were retrieved. Search results were reviewed to eliminate articles that were not relevant or were duplicates. Results: Three hundred and thirty valid articles were retrieved from PubMed and PsycINFO from 2006 to 2010. Results were compared with those of 1996–2005. The year with the highest number of articles published was 2008 (n = 96). The most productive countries, in terms of number of articles published, were China (n = 67), the United States (n = 56), the United Kingdom (n = 47), and Taiwan (n = 33). The most commonly used language was English (70.3%), followed by Chinese (15.4%). Articles were published in 153 different journals. The journal that published the most articles was Cyberpsychology and Behavior (n = 73), followed by Chinese Journal of Clinical Psychology (n = 27) and International Journal of Mental Health and Addiction (n = 16). Internet was the area most frequently studied, with an increasing interest in other areas such as online video games and cell phones. Conclusions: The number of publications on technological addictions reached a peak in 2008. The scientific contributions of China, Taiwan, and Korea are overrepresented compared to other scientific fields such as drug addiction. The inclusion of Internet Gaming Disorder in the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition

  16. Key scientific challenges in current rechargeable non-aqueous Li-O2 batteries: experiment and theory.

    Science.gov (United States)

    Bhatt, Mahesh Datt; Geaney, Hugh; Nolan, Michael; O'Dwyer, Colm

    2014-06-28

    Rechargeable Li-air (henceforth referred to as Li-O2) batteries provide theoretical capacities that are ten times higher than that of current Li-ion batteries, which could enable the driving range of an electric vehicle to be comparable to that of gasoline vehicles. These high energy densities in Li-O2 batteries result from the atypical battery architecture which consists of an air (O2) cathode and a pure lithium metal anode. However, hurdles to their widespread use abound with issues at the cathode (relating to electrocatalysis and cathode decomposition), lithium metal anode (high reactivity towards moisture) and due to electrolyte decomposition. This review focuses on the key scientific challenges in the development of rechargeable non-aqueous Li-O2 batteries from both experimental and theoretical findings. This dual approach allows insight into future research directions to be provided and highlights the importance of combining theoretical and experimental approaches in the optimization of Li-O2 battery systems.

  17. Literatura científica brasileira sobre transtornos do espectro autista Brazilian scientific literature about autism spectrum disorders

    Directory of Open Access Journals (Sweden)

    Maria Cristina Triguero Veloz Teixeira

    2010-01-01

    Full Text Available OBJETIVOS: O presente estudo refere-se a uma revisão sistemática, cujo objetivo foi conduzir uma análise da produção científica de autores brasileiros sobre Transtornos do espectro autista (TEA, no período de 2002 a 2009. MÉTODOS: A busca bibliográfica foi realizada nas bases de dados: PUBMED, SciELO, LILACS e portal CAPES, incluindo diversos descritores, tais como autismo e transtorno invasivo do desenvolvimento. RESULTADOS: Um total de 93 artigos foi identificado, tendo sido publicados, sobretudo por autores da região Sudeste e de universidades públicas. Aproximadamente um terço dos artigos foi publicado em revistas com algum fator de impacto variando entre 0,441 e 3,211; sendo a maioria dos artigos baseada em amostras pequenas. Foram identificadas 140 dissertações e teses; 82,1% eram dissertações de mestrado. O principal tema de pesquisa abordado neste material relacionou-se a programas de intervenção para TEA. CONCLUSÃO: Esta revisão mostra o interesse de pesquisadores brasileiros na temática dos TEA, entretanto, uma parte considerável dessa produção científica se concentra em dissertações/teses e a minoria em artigos científicos publicados em revistas com elevado fator de impacto. Os resultados desta revisão sistemática mostram a necessidade de novos estudos com amostras maiores que levariam a um maior impacto e visibilidade da produção científica brasileira relativa aos TEA.OBJECTIVE: This study is a systematic review aiming to conduct a general analysis of the scientific production covering publications of Brazilian authors about ASD in the period from 2002 to 2009. METHODS: The bibliographic search was conducted in the following scientific databases: PUBMED, SciELO, LILACS and portal CAPES, by using keywords such as autism and pervasive developmental disorders. RESULTS: A total of 93 papers were identified mainly produced by authors from tSoutheast Brazil and from public universities. Approximately one

  18. Scientific publications in nursing journals from Mainland China, Taiwan, and Hong Kong: a 10-year survey of the literature

    Directory of Open Access Journals (Sweden)

    Di Zhang

    2016-03-01

    Full Text Available Background: China has witnessed remarkable progress in scientific performance in recent years. However, the quantity and quality of nursing publications from three major regions (Mainland China, Taiwan, and Hong Kong have not been reported. This study aimed to investigate the characteristics of scientific research productivity from Mainland China, Taiwan, and Hong Kong in the field of nursing. Methods: Articles published in the 110 nursing journals originating from Mainland China, Taiwan, and Hong Kong between 2005 and 2014 were retrieved from the Web of Science. The total number of articles published, the impact factor, and the citation count were analyzed. Results: There were 2,439 publications between 2005 and 2014 from China, including 438 from Mainland China, 1,506 from Taiwan, and 495 from Hong Kong. There was a significant increase in publications for these three regions (p < 0.05, especially for Mainland China, with a 59.50-fold increase experienced. From 2011, the number of publications from Mainland China exceeded that from Hong Kong. Taiwan had the highest total journal impact factor (2,142.81, followed by Hong Kong (720.39 and Mainland China (583.94. The mean journal impact factor from Hong Kong (1.46 was higher than that from Taiwan (1.42 and Mainland China (1.33. Taiwan had the highest total citation count (8,392, followed by Hong Kong (3,785 and Mainland China (1,493. The mean citation count from Hong Kong (7.65 was higher than that from Taiwan (5.57 and Mainland China (3.41. The Journal of Clinical Nursing was the most popular journal in the three regions. Discussion: Chinese contributions to the field of nursing have significantly increased in the past ten years, particularly from Mainland China. Taiwan is the most productive region in China. Hong Kong had the highest-quality research output, according to mean journal impact factor and mean citation count.

  19. Scientific publications in nursing journals from Mainland China, Taiwan, and Hong Kong: a 10-year survey of the literature.

    Science.gov (United States)

    Zhang, Di; Wang, Xiaming; Yuan, Xueru; Yang, Li; Xue, Yu; Xie, Qian

    2016-01-01

    China has witnessed remarkable progress in scientific performance in recent years. However, the quantity and quality of nursing publications from three major regions (Mainland China, Taiwan, and Hong Kong) have not been reported. This study aimed to investigate the characteristics of scientific research productivity from Mainland China, Taiwan, and Hong Kong in the field of nursing. Articles published in the 110 nursing journals originating from Mainland China, Taiwan, and Hong Kong between 2005 and 2014 were retrieved from the Web of Science. The total number of articles published, the impact factor, and the citation count were analyzed. There were 2,439 publications between 2005 and 2014 from China, including 438 from Mainland China, 1,506 from Taiwan, and 495 from Hong Kong. There was a significant increase in publications for these three regions (p publications from Mainland China exceeded that from Hong Kong. Taiwan had the highest total journal impact factor (2,142.81), followed by Hong Kong (720.39) and Mainland China (583.94). The mean journal impact factor from Hong Kong (1.46) was higher than that from Taiwan (1.42) and Mainland China (1.33). Taiwan had the highest total citation count (8,392), followed by Hong Kong (3,785) and Mainland China (1,493). The mean citation count from Hong Kong (7.65) was higher than that from Taiwan (5.57) and Mainland China (3.41). The Journal of Clinical Nursing was the most popular journal in the three regions. Chinese contributions to the field of nursing have significantly increased in the past ten years, particularly from Mainland China. Taiwan is the most productive region in China. Hong Kong had the highest-quality research output, according to mean journal impact factor and mean citation count.

  20. Scientific publication in orthopedics journals from Chinese authors: a survey of 10-year survey of the literature.

    Science.gov (United States)

    Wang, Jing; Zhao, Chenglong; Chu, Jianjun; Yang, Cheng; Kong, Jinhai; Sun, Zhengwang; Xiao, Hui; Liu, Tielong; Xiao, Jianru

    2015-08-01

    In the scientific community, a scientist's productivity is usually measured by his scientific output. The productivity of a group, an institution or, on a larger scale, a country can be assessed in similar manner. This study aims to show the contribution of Chinese authors to orthopedics research, from three major regions, namely Mainland China, Taiwan, and Hong Kong. Articles published in 63 orthopedics journals originating from Mainland China, Taiwan, and Hong Kong from 2003 to 2012 were retrieved from the PubMed database and Journal Citation Report. Quantitative and qualitative analyses were conducted for the total number of articles, clinical trials, randomized controlled trails, case reports, impact factors (IF), citations, and articles published in high-impact journals. There were totally 3473 articles from Mainland China (1859), Taiwan (1111), and Hong Kong (503) from 2003 to 2012, showing gradual increase from 2003 to 2012. From 2006 onward, the number of published articles from Mainland China exceeded that from Hong Kong and exceeded that from Taiwan in 2008. The accumulated IF of articles from Mainland China (3746.21) was higher than that from Taiwan (2466.74) and that from Hong Kong (1089.35). However, Taiwan witnessed the highest mean IF (2.22), followed by Hong Kong (2.17), and Mainland China (2.02). Hong Kong displayed the highest mean citations of each article (9.35), followed by Taiwan (9.12), and Mainland China (5.71). By contract, Spine was the most popular journal to choose in these three regions. The total number of orthopedics articles in China increased markedly from 2003 to 2012. Of the three regions, Mainland China published the most articles, clinical trials, randomized controlled trails, and case reports. In general, Spine was the most popular journal to choose in the three regions.

  1. FACTORS OF RESISTANCE AGAINST AIR CURRENT ESTABLISHED BY MEASUREMENT AND FACTOR ESTIMATED BY LITERATURE

    Directory of Open Access Journals (Sweden)

    Vladimir Rendulić

    1996-12-01

    Full Text Available Specific resistance (R100 for underground mine rooms can he calculated by the constant (C. Constant (C enables defining of the resistance for any relation of dimensions F3/U in similar mine rooms. Considerable anomalies were found by comparison of the resistance factor calculated from measurement data with estimated value of the factor from specialized literature on planning similar ventilation structures (the paper is published in Croatian.

  2. Autopsy report for a caffeine intoxication case and review of the current literature

    OpenAIRE

    Yamamoto, Takuma; Yoshizawa, Katsuhiko; Kubo, Shin-ichi; EMOTO, Yuko; Hara, Kenji; Waters, Brian; Umehara, Takahiro; Murase, Takehiko; Ikematsu, Kazuya

    2014-01-01

    Caffeine (1,3,7-trimethylxanthine) is a popular mild central nervous system stimulant found in the leaves, seeds and fruits of various plants and in foodstuffs such as coffee, tea, and chocolate, among others. Caffeine is widely used and is not associated with severe side effects when consumed at relatively low doses. Although rarely observed, overdoses can occur. However, only a few fatal caffeine intoxication cases have been reported in the literature. Herein, we report the pathological exa...

  3. Aripiprazole in the maintenance treatment of bipolar disorder: a critical review of the evidence and its dissemination into the scientific literature.

    Directory of Open Access Journals (Sweden)

    Alexander C Tsai

    2011-05-01

    Full Text Available BACKGROUND: Aripiprazole, a second-generation antipsychotic medication, has been increasingly used in the maintenance treatment of bipolar disorder and received approval from the U.S. Food and Drug Administration for this indication in 2005. Given its widespread use, we sought to critically review the evidence supporting the use of aripiprazole in the maintenance treatment of bipolar disorder and examine how that evidence has been disseminated in the scientific literature. METHODS AND FINDINGS: We systematically searched multiple databases to identify double-blind, randomized controlled trials of aripiprazole for the maintenance treatment of bipolar disorder while excluding other types of studies, such as open-label, acute, and adjunctive studies. We then used a citation search to identify articles that cited these trials and rated the quality of their citations. Our evidence search protocol identified only two publications, both describing the results of a single trial conducted by Keck et al., which met criteria for inclusion in this review. We describe four issues that limit the interpretation of that trial as supporting the use of aripiprazole for bipolar maintenance: (1 insufficient duration to demonstrate maintenance efficacy; (2 limited generalizability due to its enriched sample; (3 possible conflation of iatrogenic adverse effects of abrupt medication discontinuation with beneficial effects of treatment; and (4 a low overall completion rate. Our citation search protocol yielded 80 publications that cited the Keck et al. trial in discussing the use of aripiprazole for bipolar maintenance. Of these, only 24 (30% mentioned adverse events reported and four (5% mentioned study limitations. CONCLUSIONS: A single trial by Keck et al. represents the entirety of the literature on the use of aripiprazole for the maintenance treatment of bipolar disorder. Although careful review identifies four critical limitations to the trial's interpretation

  4. Declaring Conflict of Interest - Current State of Affairs in the Ophthalmic Literature.

    Science.gov (United States)

    Schaefer, Jamie Lea; Aubert Bonn, Noemie; Craenen, Geert

    2017-01-01

    The importance of transparency with financial ties in biomedical research is widely recognized, and most peer-reviewed journals require declarations of Conflicts of Interest (COI). Nonetheless, variability in the consistency of declarations of COI has been sparsely assessed. To assess consistency and rates of COI declarations in the ophthalmic literature and the effectiveness of journal COI policies. We analyzed consistency and completeness of declaration of COI in the ophthalmic literature and compared the levels of completeness to specific journal requirements. Six-hundred forty-two peer reviewed articles satisfied the inclusion criteria. In 64%, COIs were unreported, in 25% declaration of COI was incomplete, and 11% of the articles reviewed had complete declaration of COI. Of the 33 journals in which the most frequently published authors' articles appeared, 10 required the authors to complete the International Committee of Medical Journal Editors (ICMJE) form or an equivalent form, but this did not affect the rates of COI declaration. In a random sampling of the most frequently published authors in the field of ophthalmology, declaration of COI was low and highly inconsistent. Requiring a standardized COI form has no significant effect on the rate of accurate COI reporting. Our findings lend support to the growing body of literature that shows that journals and editors may need to take a more active role in ensuring accurate and consistent COI reporting.

  5. Anticoagulant therapy in patients undergoing dental interventions: a critical review of the literature and current perspectives.

    Science.gov (United States)

    Isola, G; Matarese, G; Cordasco, G; Rotondo, F; Crupi, A; Ramaglia, L

    2015-02-01

    Patients treated with oral anticoagulant therapy (OAT) represent an issue to the dentist, as an increasing number of people are using anticoagulant drugs for cardiovascular disease. The choice of an eventual suspension or continuation of anticoagulant therapy is important when considering an efficient management of the patient. Patients in anticoagulant therapy and requiring dental procedures sometimes represent therapeutic concerns especially concerning the suspension of the anticoagulant treatment. At the moment there is no consensus among international experts of a possible discontinuation of therapy before invasive dental procedures. In this paper, the authors try to focus on this topic through a critical review of the literature. Most of the studies suggest the continuation of the anticoagulant treatment with heparin before invasive oral surgical interventions. Based on the data of the literature, two rules must be adopted in clinical practice: 1) maintenance of anticoagulation related to the international normalized ratio (INR); 2) local application of antifibrinolytic agents to ensure a proper hemostatic process. Given the widespread use of anticoagulant drugs in cardiovascular disease, dentists must often face the problem of the therapy and, since there is no consensus on the management of these patients, the authors propose, after a thorough critical review of the literature, the implementation of a multiphase protocol of surgical approach to be implemented with safety in daily clinical practice.

  6. Waldenström Macroglobulinemia in Hepatitis C: Case Report and Review of the Current Literature

    Directory of Open Access Journals (Sweden)

    Ryan Nipp

    2014-01-01

    Full Text Available Background. Recent literature has associated hepatitis C virus with the development of non-Hodgkin lymphoma. Hepatitis C virus infection appears to promote lymphoproliferation, providing a plausible mechanism for a causative association; however, despite prior reports of patients with comorbid hepatitis C infection and Waldenström macroglobulinemia, the literature is in disagreement regarding whether there exists an association between these two conditions. Case Presentation. This case report describes a 57-year-old African-American male with chronic hepatitis C infection and cryoglobulinemia who presented with several episodes of transient confusion and paralysis and was found to have symptomatic hyperviscosity. The recognition of his condition was facilitated by characteristic findings on ophthalmologic examination. He was subsequently diagnosed with Waldenström macroglobulinemia on bone marrow biopsy. Conclusions. An up to date, comprehensive review of the literature suggests an association between hepatitis C and Waldenström macroglobulinemia. Data on optimal treatment of patients with comorbid hepatitis C infection and Waldenström macroglobulinemia is limited. We have provided a comprehensive review of previously explored treatment options to guide management of other similar patients. Our patient has since been treated with repeated plasmapheresis with a plan to pursue antiviral therapy.

  7. Evidence-based medicine in bovine, equine and canine reproduction: quality of current literature.

    Science.gov (United States)

    Simoneit, C; Heuwieser, W; Arlt, S

    2011-10-01

    The objective was to evaluate deficits and differences of published literature on reproduction in cattle, horses, and dogs. A literature search was conducted in the databases Medline and Veterinary Science. Approximately five times more articles on clinical bovine reproduction (n = 25 910) were found compared to canine (n = 5 015) and equine (n = 5 090) reproduction. For the evaluation of the literature, a checklist was used. A subset of 600 articles published between 1999 and 2008 was randomly selected. After applying exclusion criteria, a total of 268 trials (86 for cattle, 99 for horses, and 83 for dogs) were evaluated and used for further analysis. For the field of canine and equine reproduction, there were fewer clinical trials with a control group compared to bovine reproduction (cattle 66%, horses 41%, and dogs 41%). For all three species investigated, few publications were identified (4%) with the highest level of evidence, i.e., controlled, randomized, and blinded trials, or meta-analyses. In cattle 33% of the publications were graded adequate to draw sound conclusions; however, only 7 and 11% were graded adequate in dogs and horses, respectively. Therefore, the veterinarian should always assess the quality of information before implementing results into practice to provide best available care for the animals. In conclusion, improvement of the quality of well-designed, conducted and reported clinical trails in animal reproduction is required.

  8. APPLICATION OF PARAMETER CONTINUATION METHOD FOR INVESTIGATION OF VIBROIMPACT SYSTEMS DYNAMIC BEHAVIOUR. PROBLEM STATE. SHORT SURVEY OF WORLD SCIENTIFIC LITERATURE

    Directory of Open Access Journals (Sweden)

    V.A. Bazhenov

    2014-12-01

    Full Text Available Authors in their works study vibroimpact system dynamic behaviour by numerical parametric continuation technique combined with shooting and Newton-Raphson’s methods. The technique is adapted to two-mass two-degree-of-freedom vibroimpact system under periodic excitation. Impact is simulated by nonlinear contact interaction force based on Hertz’s contact theory. Stability or instability of obtained periodic solutions is determined by monodromy matrix eigenvalues (multipliers based on Floquet’s theory. In the present paper we describe the state of problem of parameter continuation method using for nonlinear tasks solution. Also we give the short survey of numerous contemporary literature in English and Russian about parameter continuation method application for nonlinear problems. This method is applied for vibroimpact problem solving more rarely because of the difficulties connected with repeated impacts.

  9. Scientific publications in laboratory medicine from mainland China, Hong Kong and Taiwan: A ten-year survey of the literature.

    Science.gov (United States)

    Liu, Ding-Hua; Cui, Wei; Yao, Yun-Tai; Jiang, Qi-Qi

    2010-10-09

    We investigated scientific publications in laboratory medicine originating from mainland China, Hong Kong and Taiwan over the past 10 years. The information about articles published in the included journals were determined by computer-searching on PubMed and data were extracted independently and analyzed in relation to the number of articles. From 2000 to 2009 there were 1166 articles published in laboratory medicine journals from the major Chinese regions (mainland China, Hong Kong and Taiwan). This exceeded Japan, Germany, the United Kingdom and France from 2005 onwards. Also, the number of articles from mainland China exceeded those from Hong Kong and Taiwan from 2004 onwards. The average impact factor (IF) from Hong Kong ranked the first, followed by mainland China, and then Taiwan. Clinica Chimica Acta seems to be the most popular laboratory medicine journal among Chinese authors. Over the past 10 years, Chinese authors have been more and more active in the field of laboratory medicine. Mainland China seems to have caught up to Hong Kong and Taiwan regarding publication of papers in this field. Copyright 2010 Elsevier B.V. All rights reserved.

  10. Analysis on the Current State of Performance Appraisal for Scientific Workers in Agricultural Sci-entific Institute%农业科研机构科研人员绩效考核现状分析

    Institute of Scientific and Technical Information of China (English)

    孔怡; 武晓亮; 蔚承祥; 苏波; 马刚

    2014-01-01

    绩效考核工作是现代人力资源管理工作中的一项重要内容[1]。文章主要阐述了农业科研机构科研人员绩效考核的现状,分析了现行农业科研人员绩效考核工作中存在的问题,以期为建立科学合理的农业科研人员绩效考核体系提供参考。%Performance appraisal is an important part of human resource management. In order to provide reference to build a more scientific performance appraisal system of agricultural scientific workers, in this article, we elaborated the state, and analyzed the problems of the current performance appraisal of agricul-tural scientific workers.

  11. Scientific publications on systematic review and meta-analysis from Chinese authors: a 10-year survey of the English literature.

    Science.gov (United States)

    Yang, Zhiping; Wu, Qiong; Wu, Kaichun; Fan, Daiming

    2012-03-01

    Systematic reviews and meta-analyses are playing an increasingly important role in clinical research and practice. This study aimed to measure the scientific production of systematic review and meta-analysis from the three major regions of China: the Mainland (ML), Hong Kong (HK), and Taiwan (TW). English articles on systematic review and meta-analysis from ML, HK, and TW from 2001 to 2010 were retrieved from the PubMed database. The total number of articles, impact factors (IF), and articles published in high-impact journals were conducted for quantity and quality comparisons among the three regions. There were 1 587 published articles from ML (1 292), HK (203), and TW (92) during the past ten years. The annual total numbers of articles in the three regions increased significantly from 2001 to 2010 (from 13 to 677). The number of articles from ML has exceeded that from TW since 2001, and surpassed that from HK in 2003. The accumulated IF of articles from ML (3 488.24) was higher than those from HK (493.16) and TW (216.39). HK had the highest average IF of 3.31, followed by ML of 2.90 and TW of 2.85. Researchers from HK published a larger proportion of papers in high-impact journals than those from ML and TW. The Cochrane Database of Systematic Reviews was the most popular journal in China. Chinese authors have been very active to enhance the systematic review and meta-analysis research over the past ten years, especially in ML. The gap between ML and the other two regions has been narrowed. But there is still considerable room for Chinese authors to improve their studies on systematic review and meta-analysis.

  12. Understanding the Neuro-ophthalmology of Head Trauma: A Review of the Current Literature.

    Science.gov (United States)

    Samra, Khawla Abu

    2014-01-01

    Head trauma is a major medical, social, economic, national, and public health priority issue in the United States. In severe head trauma, the overwhelming clinical manifestations are so compelling that damage to the visual system is most likely to be ignored. Both the afferent and efferent visual systems are susceptible to injury after head trauma, and physicians should be aware of the visual system and perform a thorough neuro-ophthalmic evaluation in patients presenting with head trauma.Most of the data available on neuro-ophthalmic complications of head trauma including cortical blindness, Horner's syndrome, traumatic internuclear ophthalmoplegia, and ocular motor palsy, comes from case reports highlighting the need for future studies to better understand these complications.This review summarizes some of the most important neuro-ophthalmic complications of head trauma including cortical blindness, Horner's syndrome, traumatic internuclear ophthalmoplegia, and ocular motor palsy. Search of the peer-reviewed literature was conducted using MEDLINE, Cumulative Index to Nursing and Allied Health Literature, Cochrane Library, Global Health, and MD Consult.

  13. Potential health effects of gasoline and its constituents: A review of current literature (1990-1997) on toxicological data.

    Science.gov (United States)

    Caprino, L; Togna, G I

    1998-03-01

    We reviewed toxicological studies, both experimental and epidemiological, that appeared in international literature in the period 1990-1997 and included both leaded and unleaded gasolines as well as their components and additives. The aim of this overview was to select, arrange, and present references of scientific papers published during the period under consideration and to summarize the data in order to give a comprehensive picture of the results of toxicological studies performed in laboratory animals (including carcinogenic, teratogenic, or embryotoxic activity), mutagenicity and genotoxic aspects in mammalian and bacterial systems, and epidemiological results obtained in humans in relation to gasoline exposure. This paper draws attention to the inherent difficulties in assessing with precision any potential adverse effects on health, that is, the risk of possible damage to man and his environment from gasoline. The difficulty of risk assessment still exists despite the fact that the studies examined are definitely more technically valid than those of earlier years. The uncertainty in overall risk determination from gasoline exposure also derives from the conflicting results of different studies, from the lack of a correct scientific approach in some studies, from the variable characteristics of the different gasoline mixtures, and from the difficulties of correctly handling potentially confounding variables related to lifestyle (e.g., cigarette smoking, drug use) or to preexisting pathological conditions. In this respect, this paper highlights the need for accurately assessing the conclusive explanations reported in scientific papers so as to avoid the spread of inaccurate or misleading information on gasoline toxicity in nonscientific papers and in mass-media messages.

  14. The role of stereopsis (three-dimensional vision) in dentistry: review of the current literature.

    Science.gov (United States)

    Syrimi, M; Ali, N

    2015-05-22

    Clinical dental work is placing increasing demands on a clinician's vision as new techniques that require fine detail become more common. High hand-eye coordination requires good visual acuity as well as other psychological and neurological qualities such as stereopsis. Stereopsis (three-dimensional vision) is the highest form of depth perception obtained by visual disparity of images formed in the retinas of two eyes. It is believed to confer functional benefits on everyday tasks such as hand-eye coordination. Although its role in depth perception has long been established, little is known regarding the importance of stereopsis in dentistry. This article reviews the role of stereopsis in everyday life and the available literature on the importance of stereopsis in dentistry.

  15. The Optimal Pain Management Approach for a Laboring Patient: A Review of Current Literature.

    Science.gov (United States)

    Kelly, Albert; Tran, Quang

    2017-05-10

    There is a general agreement that a patient in labor should be given the option to have an epidural block for pain management. Despite this consensus, there are differences in practice patterns as to when to initiate an epidural and how to minimize its impact on the duration and outcome of a patient's labor. A review of the literature suggests epidural analgesia does prolong stages one and two of labor, but not significantly. Cesarean delivery rates are not affected by the early initiation of epidural analgesia. The use of various adjuvants such as opioids, clonidine, and neostigmine in conjunction with local anesthetics solution can significantly reduce the severity of motor blockade and the need for assisted vaginal delivery.

  16. Experimentally determined mechanical properties of, and models for, the periodontal ligament: critical review of current literature.

    Science.gov (United States)

    Fill, Ted S; Carey, Jason P; Toogood, Roger W; Major, Paul W

    2011-01-01

    Introduction. This review is intended to highlight and discuss discrepancies in the literature of the periodontal ligament's (PDL) mechanical properties and the various experimental approaches used to measure them. Methods. Searches were performed on biomechanical and orthodontic publications (in databases: Compendex, EMBASE, MEDLINE, PubMed, ScienceDirect, and Scopus). Results. The review revealed that significant variations exist, some on the order of six orders of magnitude, in the PDL's elastic constants and mechanical properties. Possible explanations may be attributable to different experimental approaches and assumptions. Conclusions. The discrepancies highlight the need for further research into PDL properties under various clinical and experimental loading conditions. Better understanding of the PDL's biomechanical behavior under physiologic and traumatic loading conditions might enhance the understanding of the PDL's biologic reaction in health and disease. Providing a greater insight into the response of the PDL would be instrumental to orthodontists and engineers for designing more predictable, and therefore more efficacious, orthodontic appliances.

  17. 科技文献搜索引擎元数据仓储建设实践*%Construction of Metadata Repository in Scientific Literature Search Engine

    Institute of Scientific and Technical Information of China (English)

    甘大广; 苏学; 张正峰

    2013-01-01

    This paper analyzes the opportunities and chal enges of a user query behavior, industry resources publishing model change on the integration of digital resources, focusing on the actual work of scientific literature search engine underlying metadata repository construction, including metadata harvesting, metadata specification, and metadata integration.%  文章分析了用户查询行为、行业资源出版模式等变化对数字资源整合的机遇与挑战,重点结合实际工作介绍了科技文献搜索引擎底层元数据仓储的建设过程,包括元数据采集、元数据规范、元数据整合等环节。

  18. Research on road traffic noise and human health in India: Review of literature from 1991 to current

    Directory of Open Access Journals (Sweden)

    Dibyendu Banerjee

    2012-01-01

    Full Text Available This article reviews the literature on research conducted during the last two decades on traffic noise impacts in India. Road traffic noise studies in India are fewer and restricted only to the metropolitan areas. The studies over the years have also focused on the monitoring, recording, analysis, modeling, and to some extent mapping related themes. Negligible studies are observed in areas of physiological and sleep research exposure-effect context. Most impact studies have been associated with annoyance and attitudinal surveys only. Little scientific literature exists related to effects of traffic noise on human physiology in the Indian context. The findings of this review search and analysis observe that very little studies are available relating to traffic noise and health impacts. All of them are subjective response studies and only a small portion of them quantify the exposure-effect chain and model the noise index with annoyance. The review of papers showed that road traffic noise is a cause for annoyance to a variety of degree among the respondents. A generalization of impacts and meta-analysis was not possible due to variability of the study designs and outputs preferred.

  19. Does deforestation promote or inhibit malaria transmission in the Amazon? A systematic literature review and critical appraisal of current evidence.

    Science.gov (United States)

    Tucker Lima, Joanna M; Vittor, Amy; Rifai, Sami; Valle, Denis

    2017-06-05

    Considerable interest in the relationship between biodiversity and disease has recently captured the attention of the research community, with important public policy implications. In particular, malaria in the Amazon region is often cited as an example of how forest conservation can improve public health outcomes. However, despite a growing body of literature and an increased understanding of the relationship between malaria and land use / land cover change (LULC) in Amazonia, contradictions have emerged. While some studies report that deforestation increases malaria risk, others claim the opposite. Assessing malaria risk requires examination of dynamic processes among three main components: (i) the environment (i.e. LULC and landscape transformations), (ii) vector biology (e.g. mosquito species distributions, vector activity and life cycle, plasmodium infection rates), and (iii) human populations (e.g. forest-related activity, host susceptibility, movement patterns). In this paper, we conduct a systematic literature review on malaria risk and deforestation in the Amazon focusing on these three components. We explore key features that are likely to generate these contrasting results using the reviewed articles and our own data from Brazil and Peru, and conclude with suggestions for productive avenues in future research.This article is part of the themed issue 'Conservation, biodiversity and infectious disease: scientific evidence and policy implications'. © 2017 The Authors.

  20. Does deforestation promote or inhibit malaria transmission in the Amazon? A systematic literature review and critical appraisal of current evidence

    Science.gov (United States)

    Tucker Lima, Joanna M.; Vittor, Amy; Rifai, Sami

    2017-01-01

    Considerable interest in the relationship between biodiversity and disease has recently captured the attention of the research community, with important public policy implications. In particular, malaria in the Amazon region is often cited as an example of how forest conservation can improve public health outcomes. However, despite a growing body of literature and an increased understanding of the relationship between malaria and land use / land cover change (LULC) in Amazonia, contradictions have emerged. While some studies report that deforestation increases malaria risk, others claim the opposite. Assessing malaria risk requires examination of dynamic processes among three main components: (i) the environment (i.e. LULC and landscape transformations), (ii) vector biology (e.g. mosquito species distributions, vector activity and life cycle, plasmodium infection rates), and (iii) human populations (e.g. forest-related activity, host susceptibility, movement patterns). In this paper, we conduct a systematic literature review on malaria risk and deforestation in the Amazon focusing on these three components. We explore key features that are likely to generate these contrasting results using the reviewed articles and our own data from Brazil and Peru, and conclude with suggestions for productive avenues in future research. This article is part of the themed issue ‘Conservation, biodiversity and infectious disease: scientific evidence and policy implications'. PMID:28438914

  1. A review of the current literature on aetiology and measurement methods of halitosis.

    NARCIS (Netherlands)

    Broek, A.M. van den; Feenstra, L.; Baat, C. de

    2007-01-01

    OBJECTIVES: This work reviews the current knowledge of aetiology and measurement methods of halitosis. DATA: Halitosis is an unpleasant or offensive odour emanating from the breath. The condition is multifactorial and may involve both oral and non-oral conditions. SOURCES: A private, monthly with ke

  2. A review of the current literature on aetiology and measurement methods of halitosis.

    NARCIS (Netherlands)

    Broek, A.M. van den; Feenstra, L.; Baat, C. de

    2007-01-01

    OBJECTIVES: This work reviews the current knowledge of aetiology and measurement methods of halitosis. DATA: Halitosis is an unpleasant or offensive odour emanating from the breath. The condition is multifactorial and may involve both oral and non-oral conditions. SOURCES: A private, monthly with ke

  3. Current Literature on Venereal Disease, 1972. Number Two. Abstracts and Bibliography.

    Science.gov (United States)

    Lea, Mildred V., Ed.

    Presented are abstracts of documents and research pertaining to the clinical description, laboratory diagnosis, management, and therapy of syphilis and gonorrhea. Abstracted case studies of other minor venereal and related diseases are also included, as are bibliographies on current research and evaluation, public health methods, and behavioral…

  4. Current Literature on Venereal Disease, 1972. Number Three. Abstracts and Bibliography.

    Science.gov (United States)

    Lea, Mildred V., Ed.

    Presented are abstracts of documents and research pertaining to the clinical description, laboratory diagnosis, management, and therapy of syphilis and gonorrhea. Abstracted case studies of other minor venereal and related diseases are also included, as are bibliographies on current research and evaluation, public health methods, and behavioral…

  5. Current Literature on Venereal Disease, 1972. Number One. Abstracts and Bibliography.

    Science.gov (United States)

    Lea, Mildred V., Ed.

    Presented are abstracts of documents and research pertaining to the clinical description, laboratory diagnosis, management, and therapy of syphilis and gonorrhea. Abstracted case studies of other minor venereal and related diseases are also included, as are bibliographies on current research and evaluation, public health methods, and behavioral…

  6. A review of the current literature on aetiology and measurement methods of halitosis.

    NARCIS (Netherlands)

    Broek, A.M. van den; Feenstra, L.; Baat, C. de

    2007-01-01

    OBJECTIVES: This work reviews the current knowledge of aetiology and measurement methods of halitosis. DATA: Halitosis is an unpleasant or offensive odour emanating from the breath. The condition is multifactorial and may involve both oral and non-oral conditions. SOURCES: A private, monthly with

  7. Current status of laparoscopic transhiatal esophagectomy for esophageal cancer patients : a systematic review of the literature

    NARCIS (Netherlands)

    Parry, K.; Ruurda, J. P.|info:eu-repo/dai/nl/257561021; van der Sluis, P. C.; van Hillegersberg, R.|info:eu-repo/dai/nl/110706242

    Minimally invasive techniques in transhiatal esophagectomy (THE) were introduced to reduce morbidity and enhance postoperative recovery. Aim of this study was to systematically review the current status and possible beneficial effects of the minimally invasive approach in THE. A systematic search

  8. LMFBR safety. 6. Review of current issues and bibliography of literature (1977)

    Energy Technology Data Exchange (ETDEWEB)

    Buchanan, J.R.; Keilholtz, G.W.

    1978-07-13

    This report discusses the current status of liquid-metal fast breeder reactor (LMFBR) development. Selected bibliographic information on LMFBRs relative to the development and safety of the breeder reactor is presented for the year 1977. The bibliography consists of approximately 198 abstracts covering research and development, operating experience, and design practices. Keyword, author, and permuted-title indexes are included for completeness.

  9. Statistical Analysis of Literatures for the Scientific Data Sharing Research%科学数据共享研究的文献计量分析

    Institute of Scientific and Technical Information of China (English)

    张翔

    2013-01-01

      The scientific data sharing is an important driving force promoting the development of modern science, which is the key element of promoting national scientific and technological innovation. Subject headings by"Science Data Shared" for academic journals without time range, searches 234 articles correlative academic paper through on the CNKI Databases under of literature retrieved in this paper, and then it analysis annual issued volume, journals distribution, core author distribution, research body distribution, science research fund funding situation and eight theme area by the SATI3.2, Ucinet6 and SPSS18.0software on samples literature, so as to provide some reference to related studies in China.%  科学数据共享是促进现代科学发展重要的推动力量,是推动国家科技创新的关键要素。以“科学数据共享”作为主题词,不限定时间范围,选择文献类型为学术期刊,通过对《中国知网学术期刊网络出版总库》的文献检索,检索到234篇相关的学术论文,综合利用SATI3.2、Ucinet6与SPSS18.0等软件对样本文献的年度发文量、期刊分布、核心作者分布、研究机构分布、科研基金资助情况以及研究主题等8个方面进行分析,从而为国内相关研究提供一定的参考。

  10. 中医药科技文献增长规律研究%Research on the Growth Law of Traditional Chinese Medicine Scientific Literature

    Institute of Scientific and Technical Information of China (English)

    刘艳芬; 梁茂新

    2011-01-01

    This paper aimed to study the growth law of traditional Chinese medicine (TCM) scientific literature.Curvilinear regression analysis is used to analyze data from TCM journals and published papers of four TCM colleges. The result of regression hypothesis test showed that the exponential model is appropriate. It is concluded that the growth of data from TCM journals and published papers were accorded with the exponential growth in Price law.The growth rate b and cumulative total of published papers are proposed as reference indexes to evaluate the level of TCM scientific research.%目的:对中医药科技文献增长规律进行研究.方法:对中医药类期刊数据和4所中医院校发表论文的数据进行曲线回归分析.结果:由回归分析假设检验的结果,表明建立指数模型是合适的.结论:中医药类期刊数据和发表论文数据均符合普赖斯提出的科技文献指数增长规律,并且提出增长率b和累积发表论文总量可作为评价中医各单位科研水平的参考指标.

  11. A review and critical analysis of the scientific literature related to 100% fruit juice and human health.

    Science.gov (United States)

    Hyson, Dianne A

    2015-01-01

    The association between the consumption of pure (100%) fruit juice (PFJ) and human health is uncertain. The current review summarizes data published between 1995 and 2012 related to PFJ with a focus on juices that are widely available and studied in forms representing native juice without supplemental nutrients or enhanced phytochemical content. The effects of apple, cranberry, grape, grapefruit, orange, and pomegranate PFJ intake on outcomes linked to cancer, cardiovascular disease, cognition, hypertension, inflammation, oxidation, platelet function, urinary tract infection, and vascular reactivity are reviewed. Implications for bodyweight regulation are also addressed. The collective data are provocative although challenges and unanswered questions remain. There are many plausible mechanisms by which PFJ might be protective, and investigation of its effects on human health and disease prevention must remain an active area of research.

  12. Combined Heart Lung Transplantation: An Updated Review of the Current Literature.

    Science.gov (United States)

    Pasupneti, Shravani; Dhillon, Gundeep; Reitz, Bruce; Khush, Kiran

    2017-10-01

    Heart lung transplantation is a viable treatment option for patients with many end-stage heart and lung pathologies. However, given the complex nature of the procedure, it is imperative that patients are selected appropriately, and the clinician is aware of the many unique aspects in management of this population. This review seeks to describe updated organ selection policies, perioperative and postoperative management strategies, monitoring of graft function, and clinical outcomes for patients after combined heart-lung transplantation in the current era.

  13. Balancing selection on immunity genes: review of the current literature and new analysis in Drosophila melanogaster.

    Science.gov (United States)

    Croze, Myriam; Živković, Daniel; Stephan, Wolfgang; Hutter, Stephan

    2016-08-01

    Balancing selection has been widely assumed to be an important evolutionary force, yet even today little is known about its abundance and its impact on the patterns of genetic diversity. Several studies have shown examples of balancing selection in humans, plants or parasites, and many genes under balancing selection are involved in immunity. It has been proposed that host-parasite coevolution is one of the main forces driving immune genes to evolve under balancing selection. In this paper, we review the literature on balancing selection on immunity genes in several organisms, including Drosophila. Furthermore, we performed a genome scan for balancing selection in an African population of Drosophila melanogaster using coalescent simulations of a demographic model with and without selection. We find very few genes under balancing selection and only one novel candidate gene related to immunity. Finally, we discuss the possible causes of the low number of genes under balancing selection. Copyright © 2016 The Authors. Published by Elsevier GmbH.. All rights reserved.

  14. Effects of colchicine on pericardial diseases: a review of the literature and current evidence

    Directory of Open Access Journals (Sweden)

    Syed Raza Shah

    2016-07-01

    Full Text Available Colchicine, extracted from the colchicum autumnale plant, used by the ancient Greeks more than 20 centuries ago, is one of the most ancient drugs still prescribed even today. The major mechanism of action is binding to microtubules thereby interfering with mitosis and subsequent modulation of polymorphonuclear leukocyte function. Colchicine has long been of interest in the treatment of cardiovascular disease; however, its efficacy and safety profile for specific conditions have been variably established in the literature. In the subset of pericardial diseases, colchicine has been shown to be effective in recurrent pericarditis and post-pericardiotomy syndrome (PPS. The future course of treatment and management will therefore highly depend on the results of the ongoing large randomized placebo-controlled clinical trial to evaluate the efficacy and safety of colchicine for the primary prevention of several postoperative complications and in the perioperative period. Also, given the positive preliminary outcomes of colchicine usage in pericardial effusions, the future therapeutical use of colchicine looks promising. Further study is needed to clarify its role in these disease states, as well as explore other its role in other cardiovascular conditions.

  15. A critical overview of the current myofascial pain literature - March 2016.

    Science.gov (United States)

    Dommerholt, Jan; Hooks, Todd; Finnegan, Michelle; Grieve, Rob

    2016-04-01

    The worldwide interest in myofascial pain syndrome (MPS) and trigger points (TrPs) is reflected in the increasing number of publications. In this overview of the literature, we included 26 studies, case reports and review articles by authors from 18 different countries. Several research groups are exploring the characteristic of TrPs such as Chen and colleagues, who continued their work on the quantification of the taut bands. Meng and colleagues studied the relationships between TrPs and central sensitization, while Yu and colleagues examined the electrophysiological characteristics that occur as a result of active TrPs. Several researchers used objective measurements to determine clinical outcomes, such as Koppenhaver and colleagues who measured objective changes in the function and nociceptive sensitivity of lumbar multifidus muscle subjects with low back pain. Turo and colleagues quantified muscle tissue changes after dry needling in chronic myofascial pain using elastography. Multiple studies explored various treatment options for TrPs, such as dry needling, injections with lidocaine or granisetron, traditional Thai massage, self-myofascial release, kinesiotaping, and monochromatic infrared photo energy, among others.

  16. Drug-nutrient interactions in the intensive care unit: literature review and current recommendations

    Science.gov (United States)

    Heldt, Tatiane; Loss, Sergio Henrique

    2013-01-01

    Objective To describe the interactions between drugs and nutrients and their frequency in the intensive care unit and to assess the professional team's awareness regarding this subject. Methods The keywords "drug interactions" and "nutrition therapy" were searched in the PubMed (specifically MeSH) electronic database. The studies were systematically reviewed for descriptions of the types of interactions between drugs and nutrients, including their frequency and consequences. Results Sixty-seven articles were found. Among these, 20 articles were appropriate for the methodology adopted and accomplished the objectives of the study. Of these 20 articles, 14 articles described interactions between drugs and enteral nutrition, three described interactions between drugs and parenteral nutrition, and three described the importance and care required to avoid such interactions. Conclusions The literature about drug and nutrient interactions is limited and suggests the inability of health care teams to recognize the potential for these interactions. Possibly, the elaboration of a protocol to evaluate drug-nutrient interactions will increase the safety and efficacy of therapeutics. PMID:23917982

  17. Current State of Development of Electricity-Generating Technologies: A Literature Review

    Directory of Open Access Journals (Sweden)

    Manfred Lenzen

    2010-03-01

    Full Text Available Electricity is perhaps the most versatile energy carrier in modern economies, and it is therefore fundamentally linked to human and economic development. Electricity growth has outpaced that of any other fuel, leading to ever-increasing shares in the overall mix. This trend is expected to continue throughout the following decades, as large—especially rural—segments of the world population in developing countries start to climb the “energy ladder” and become connected to power grids. Electricity therefore deserves particular attention with regard to its contribution to global greenhouse gas emissions, which is reflected in the ongoing development of low-carbon technologies for power generation. The focus of this updated review of electricity-generating technologies is twofold: (a to provide more technical information than is usually found in global assessments on critical technical aspects, such as variability of wind power, and (b to capture the most recent findings from the international literature. This report covers eight technologies. Seven of these are generating technologies: hydro-, nuclear, wind, photovoltaic, concentrating solar, geothermal and biomass power. The remaining technology is carbon capture and storage. This selection is fairly representative for technologies that are important in terms of their potential capacity to contribute to a low-carbon world economy.

  18. Life-threatening complications after ureteroscopy for urinary stones: survey and revision of the current literature.

    Science.gov (United States)

    Cindolo, Luca; Castellan, Pietro; Primiceri, Giulia; Hoznek, Andras; Cracco, Cecilia M; Scoffone, Cesare M; Galfano, Antonio; Petralia, Giovanni; DE Angelis, Michele; Annino, Filippo; Malacasa, Emilio; Cormio, Luigi; Acquati, Pietro; DE Lorenzis, Elisa; Maugeri, Orazio; Arena, Giuseppe; Celia, Antonio; Giusti, Guido; Schips, Luigi

    2017-02-01

    Retrograde ureteroscopy (URS) has become a common procedure for the management of urinary stones. Although its efficacy and safety are well known, the literature about major complications is still poor. This study highlighted some cases of life-threatening complications after semirigid ureteroscopy (s-URS) or flexible ureteroscopy (f-URS). We enrolled experienced endourologists (more than 75 cases/year in the last 3 years) and we performed a survey asking to review their series and report the cases encumbered by major complications (Clavien-Dindo IIIb-IV grade). Eleven urologists reported on 12 major complications (4 after s-URS, 8 after f-URS). Eight patients developed a kidney injury, 1 an arteriovenous fistula, 2 a ureter avulsion and 1 acute sepsis. Six patients underwent open nephrectomy, two surgical repair, one open pyeloplasty, one coil artery embolization and two superselective artery embolization. Guidelines and clinical practice give useful recommendations about intraoperative safety and prevention of life-threatening events. The careful postoperative observation and the surgical active treatment of this complications play a key role in reducing morbidity, kidney loss and mortality. This study encourages a strict and active care of patients, supports a routine reporting of complications, and highlights the need for systematic use of standardized classification systems.

  19. Effects of colchicine on pericardial diseases: a review of the literature and current evidence

    Science.gov (United States)

    Shah, Syed Raza; Alweis, Richard; Shah, Syed Arbab; Arshad, Mohammad Hussham; Manji, Adil Al-Karim; Arfeen, Arham Amir; Javed, Maheen; Shujauddin, Syed Muhammad; Irfan, Rida; Shabbir, Sakina; Shaikh, Shehryar

    2016-01-01

    Colchicine, extracted from the colchicum autumnale plant, used by the ancient Greeks more than 20 centuries ago, is one of the most ancient drugs still prescribed even today. The major mechanism of action is binding to microtubules thereby interfering with mitosis and subsequent modulation of polymorphonuclear leukocyte function. Colchicine has long been of interest in the treatment of cardiovascular disease; however, its efficacy and safety profile for specific conditions have been variably established in the literature. In the subset of pericardial diseases, colchicine has been shown to be effective in recurrent pericarditis and post-pericardiotomy syndrome (PPS). The future course of treatment and management will therefore highly depend on the results of the ongoing large randomized placebo-controlled clinical trial to evaluate the efficacy and safety of colchicine for the primary prevention of several postoperative complications and in the perioperative period. Also, given the positive preliminary outcomes of colchicine usage in pericardial effusions, the future therapeutical use of colchicine looks promising. Further study is needed to clarify its role in these disease states, as well as explore other its role in other cardiovascular conditions. PMID:27406462

  20. Transcutaneous Ultrasound: Elastographic Lymph Node Evaluation. Current Clinical Applications and Literature Review.

    Science.gov (United States)

    Chiorean, Liliana; Barr, Richard G; Braden, Barbara; Jenssen, Christian; Cui, Xin-Wu; Hocke, Michael; Schuler, Andreas; Dietrich, Christoph F

    2016-01-01

    Distinguishing malignant versus benign lymphadenopathies is a major diagnostic dilemma in clinical medicine. Metastatic deposits in normal-sized lymph nodes (LNs) can be smaller than a millimeter, thus presenting a diagnostic challenge. In most clinical settings, however, enlarged LNs detected on imaging need to be classified as malignant or benign. Ultrasound seems to be a very reliable method for LN characterization because of the high resolution, especially in the subcutaneous areas. However, B-mode and Doppler-ultrasound criteria for characterization of a lymphadenopathy as benign or malignant are lacking specificity. Newer methods such as elastography seem to be valuable for identifying metastatic deposits within LNs and may help discriminate malignant and benign LNs. This review summarizes the different elastographic methods available and provides an overview of the relevant publications. According to the literature, elastography can be used for identifying metastatic deposits, to guide fine needle aspiration and to non-invasively choose the most suspicious LN of a group of enlarged LNs for targeted biopsy.

  1. Current status of pediatric kidney transplantation in China: data analysis of Chinese Scientific Registry of Kidney Transplantation

    Institute of Scientific and Technical Information of China (English)

    Liu Longshan; Zhang Huanxi; Fu Qian; Chen Liping; Sun Chuanhou; Xiong Yunyi; Shi Bingyi

    2014-01-01

    Background Kidney transplantation (KTx) is the primary therapy for children with renal failure.Unlike KTx in adult patients,it is commonly agreed that pediatric KTx in China is far behind that of America.There has been no systematic analysis of Chinese pediatric KTx reported.This study aimed to demonstrate the current status of pediatric KTx in China.Methods Registry data of pediatric KTx (1983-2012) from Chinese Scientific Registry of Kidney Transplantation (CSRKT) were retrospectively analyzed.Results There were 851 pediatric KTx from 102 transplant units.The recipients were (15.4±2.5) years of age,93.9% of who were over 10 years old.Chronic glomerulonephritis and pyelonephritis accounted for 75.6% of recognized primary diseases.Allografts were from deceased donors (72.2%) or living donation (27.7%).The patient survival for 1,3,5,and 10 years was 96.9%,94.2%,92.3%,and 92.3% and the graft survival was 94.6%,91.4%,86.3%,and 79.2%,respectively.The majority of post-transplant complications were acute rejection and infections.Annual transplant reached the peak in 2008 (n=114),and decreased sharply in 2006 (n=41) and 2010 (n=57).The percentage of pediatric KTx in total KTx was highest in 2007 (1.95%) and decreased to trough level in 2010 (1.0%).Living donation increased by 32.5-folds from 2004 to 2008 and then decreased by 86.6% till 2010.The percentage of living donation in pediatric or total KTx dynamically changed in a similar manner,while living donation ratio in pediatric KTx was much higher.Conclusions Kidney transplant can provide long-term benefits to pediatric recipients.Rejection and infections are worthy of concern during follow-up.Pediatric kidney transplant in China is very much lagging behind that in developed countries.Living donation played an important role in its development in the past decades.New strategies for implementation are encouraged to increase the priority of uremic children in organ allocation so as to

  2. Current status of pediatric kidney transplantation in China: data analysis of Chinese Scientific Registry of Kidney Transplantation.

    Science.gov (United States)

    Liu, Longshan; Zhang, Huanxi; Fu, Qian; Chen, Liping; Sun, Chuanhou; Xiong, Yunyi; Shi, Bingyi; Wang, Changxi

    2014-01-01

    Kidney transplantation (KTx) is the primary therapy for children with renal failure. Unlike KTx in adult patients, it is commonly agreed that pediatric KTx in China is far behind that of America. There has been no systematic analysis of Chinese pediatric KTx reported. This study aimed to demonstrate the current status of pediatric KTx in China. Registry data of pediatric KTx (1983-2012) from Chinese Scientific Registry of Kidney Transplantation (CSRKT) were retrospectively analyzed. There were 851 pediatric KTx from 102 transplant units. The recipients were (15.4±2.5) years of age, 93.9% of who were over 10 years old. Chronic glomerulonephritis and pyelonephritis accounted for 75.6% of recognized primary diseases. Allografts were from deceased donors (72.2%) or living donation (27.7%). The patient survival for 1, 3, 5, and 10 years was 96.9%, 94.2%, 92.3%, and 92.3% and the graft survival was 94.6%, 91.4%, 86.3%, and 79.2%, respectively. The majority of post-transplant complications were acute rejection and infections. Annual transplant reached the peak in 2008 (n = 114), and decreased sharply in 2006 (n = 41) and 2010 (n = 57). The percentage of pediatric KTx in total KTx was highest in 2007 (1.95%) and decreased to trough level in 2010 (1.0%). Living donation increased by 32.5-folds from 2004 to 2008 and then decreased by 86.6% till 2010. The percentage of living donation in pediatric or total KTx dynamically changed in a similar manner, while living donation ratio in pediatric KTx was much higher. Kidney transplant can provide long-term benefits to pediatric recipients. Rejection and infections are worthy of concern during follow-up. Pediatric kidney transplant in China is very much lagging behind that in developed countries. Living donation played an important role in its development in the past decades. New strategies for implementation are encouraged to increase the priority of uremic children in organ allocation so as to promote its progress in China.

  3. Scientific collaboration: a social network analysis based on literature of animal-derived regenerative implantable medical devices.

    Science.gov (United States)

    Yu, Shu-Yang; Wang, Hong-Man

    2016-09-01

    The collaboration network of English publications on animal-derived regenerative implantable medical devices based on tissue engineering technology and its evolving processes and current states were mapped in this paper. A total of 10 159 English papers published before 1 January 2015 were obtained in eight databases. Social network analysis was conducted on these papers by utilizing UCINET software and Statistical Analysis Software for Informatics researched and developed by Peking University. The collaboration network has evolved from scattered formation to single-core dominated, and then to a core-edge one; collaboration has become more frequent and wider; network density and centrality have decreased; USA, UK and China are the top three countries with Wake Forest University, Harvard University and Tufts University being the top three contributing institutions cooperated mostly during the period between 2010 and 2014; plenty of edge institutes exist. In conclusion, more collaboration among different institutions and countries is needed; Edge institutions and developing countries should expand their scope of collaboration.

  4. Review of the current literature as a preparatory tool for the trauma content of the Orthopaedic in-Training Examination.

    Science.gov (United States)

    Farjoodi, Payam; Marker, David R; McCallum, Jeremy R; Frassica, Frank J; Mears, Simon C

    2011-05-18

    Currently, the only standardized evaluation of trauma knowledge throughout orthopedic training is found in the Orthopaedic In-Training Examination, which is administered annually to all residents by the American Academy of Orthopaedic Surgeons. Our goals were to assess the Orthopaedic In-Training Examination to (1) determine the content of the trauma questions, (2) identify the content of the 3 most frequently referenced journals on the answer keys, and (3) evaluate the correlation between those contents.We reviewed the trauma-related Orthopaedic In-Training Examination questions and answer keys for 2002 through 2007. Content for test questions and cited literature was assessed with the same criteria: (1) category type, (2) anatomic location, (3) orthopedic focus, and (4) treatment type. For each of the 3 most frequently referenced journals, we weighted content by dividing the number of times it was referenced by the number of its trauma-related articles. We then compared the journal data individually and collectively to the data from the Orthopaedic In-Training Examination trauma questions. A chi-square analysis with Yates correction was used to determine differences. Questions and literature were similar in the most frequently addressed items in each of the 4 areas: category type (taxonomy 3, treatment), 52.4% and 60.7%, respectively; anatomic location (femur), 23.3% and 27.7%, respectively; orthopedic focus (fracture), 51.0% and 56.5%, respectively; and treatment type (multiple/nonspecific), 39.0% and 35.4%, respectively.The content correlation found between the questions and literature supports the idea that reviewing current literature may help prepare for the trauma content on the Orthopaedic In-Training Examination.

  5. Occlusion in implant dentistry. A review of the literature of prosthetic determinants and current concepts.

    Science.gov (United States)

    Gross, M D

    2008-06-01

    Today the clinician is faced with widely varying concepts regarding the number, location, distribution and inclination of implants required to support the functional and parafunctional demands of occlusal loading. Primary clinical dilemmas of planning for maximal or minimal numbers of implants, their axial inclination, lengths and required volume and quality of supporting bone remain largely unanswered by adequate clinical outcome research. Planning and executing optimal occlusion schemes is an integral part of implant supported restorations. In its wider sense this includes considerations of multiple inter-relating factors of ensuring adequate bone support, implant location number, length, distribution and inclination, splinting, vertical dimension aesthetics, static and dynamic occlusal schemes and more. Current concepts and research on occlusal loading and overloading are reviewed together with clinical outcome and biomechanical studies and their clinical relevance discussed. A comparison between teeth and implants regarding their proprioceptive properties and mechanisms of supporting functional and parafunctional loading is made and clinical applications made regarding current concepts in restoring the partially edentulous dentition. The relevance of occlusal traumatism and fatigue microdamage alone or in combination with periodontal or peri-implant inflammation is reviewed and applied to clinical considerations regarding splinting of adjacent implants and teeth, posterior support and eccentric guidance schemes. Occlusal restoration of the natural dentition has classically been divided into considerations of planning for sufficient posterior support, occlusal vertical dimension and eccentric guidance to provide comfort and aesthetics. Mutual protection and anterior disclusion have come to be considered as acceptable therapeutic modalities. These concepts have been transferred to the restoration of implant-supported restoration largely by default. However, in

  6. Scientific publications on primary biliary cirrhosis from 2000 through 2010: an 11-year survey of the literature.

    Science.gov (United States)

    Qin, Baodong; Liang, Yan; Yang, Zaixing; Zhong, Renqian

    2012-01-01

    Primary biliary cirrhosis (PBC) is a chronic liver disease characterized by intrahepatic bile-duct destruction, cholestasis, and fibrosis. It can lead to cirrhosis and eventually liver failure. PBC also shows some regional differences with respect to incidence and prevalence that are becoming more pronounced each year. Recently, researchers have paid more attention to PBC. To evaluate the development of PBC research during the past 11 years, we determined the quantity and quality of articles on this subject. We also compared the contributions of scientists from the US, UK, Japan, Italy, Germany, and China. The English-language papers covering PBC published in journals from 2000 through 2010 were retrieved from the PubMed database. We recorded the number of papers published each year, analyzed the publication type, and calculated the accumulated, average impact factors (IFs) and citations from every country. The quantity and quality of articles on PBC were compared by country. We also contrasted the level of PBC research in China and other countries. The total number of articles did not significantly increase during the past 11 years. The number of articles from the US exceeded those from any other country; the publications from the US also had the highest IFs and the most citations. Four other countries showed complex trends with respect to the quantity and quality of articles about PBC. The researchers from the US have contributed the most to the development of PBC research. They currently represent the highest level of research. Some high-level studies, such as RCTs, meta-analyses, and in-depth basic studies should be launched. The gap between China and the advanced level is still enormous. Chinese investigators still have a long way to go.

  7. LMFBR safety. 1. Review of current issues and bibliography of literature, 1960--1969

    Energy Technology Data Exchange (ETDEWEB)

    Buchanan, J.R.; Keilholtz, G.W.

    1976-08-16

    This report discusses the current status of liquid-metal fast breeder (LMFBR) development and one of the principal safety issues, a hypothetical core-disruptive accident (HCDA). Bibliographic information on worldwide LMFBRs relative to the development of the breeder reactor as a safe source of nuclear power is presented for the period 1960 through 1969. The bibliography consists of 1560 abstracts covering early research and development and operating experiences leading up to the present design practices that are necessary for the licensing of breeder reactors. Key-word, author, and permuted-title indexes are included for completeness.

  8. LMFBR safety. 5. Review of current issues and bibliography of literature (1975--1976)

    Energy Technology Data Exchange (ETDEWEB)

    Buchanan, J.R.; Keilholtz, G.W.

    1977-06-08

    The current status of liquid-metal fast breeder reactor (LMFBR) development and one of the principal safety issues, a hypothetical core-disruptive accident (HCDA), are discussed. Bibliographic information on worldwide LMFBRs relative to the development and safety of the breeder reactor is presented for the period 1975 through 1976. The bibliography consists of approximately 1618 abstracts covering early research and development and operating experiences leading up to the present design practices that are necessary for the licensing of breeder reactors. Keyword, author, and permuted-title indexes are included for completeness.

  9. LMFBR safety. 4. Review of current issues and bibliography of literature (1974--1975)

    Energy Technology Data Exchange (ETDEWEB)

    Buchanan, J.R.; Keilholtz, G.W.

    1977-03-21

    This report discusses the current status of liquid-metal fast breeder reactor (LMFBR) development and one of the principal safety issues, a hypothetical core-disruptive accident (HCDA). Bibliographic information on worldwide LMFBRs relative to the development of the breeder reactor as a safe source of nuclear power is presented for the period 1974 through 1975. The bibliography consists of approximately 1554 abstracts covering early research and development and operating experiences leading up to the present design practices that are necessary for the licensing of breeder reactors. Key-word, author, and permuted-title indexes are included for completeness.

  10. Breast reconstruction with anatomical implants: A review of indications and techniques based on current literature

    Directory of Open Access Journals (Sweden)

    Marco Gardani

    2017-09-01

    Full Text Available One important modality of breast cancer therapy is surgical treatment, which has become increasingly less mutilating over the last century. Breast reconstruction has become an integrated part of breast cancer treatment due to long-term psychosexual health factors and its importance for breast cancer survivors. Both autogenous tissue-based and implant-based reconstruction provides satisfactory reconstructive options due to better surgeon awareness of “the ideal breast size”, although each has its own advantages and disadvantages. An overview of the current options in breast reconstruction is presented in this article.

  11. LMFBR safety. 2. Review of current issues and bibliography of literature, 1970--1972

    Energy Technology Data Exchange (ETDEWEB)

    Buchanan, J.R.; Keilholtz, G.W.

    1976-11-22

    This report discusses the current status of liquid-metal fast breeder reactor (LMFBR) development and one of the principal safety issues, a hypothetical core-disruptive accident (HCDA). Bibliographic information on worldwide LMFBRs relative to the development of the breeder reactor as a safe source of nuclear power is presented for the period 1970 through 1972. The bibliography consists of approximately 1620 abstracts covering early research and development and operating experiences leading up to the present design practices that are necessary for the licensing of breeder reactors. Key-word, author, and permuted-title indexes are included for completeness.

  12. LMFBR safety. 3. Review of current issues and bibliography of literature (1972--1974)

    Energy Technology Data Exchange (ETDEWEB)

    Buchanan, J.R.; Keilholtz, G.W.

    1977-02-24

    The report discusses the current status of liquid-metal fast breeder reactor (LMFBR) development and one of the principal safety issues, a hypothetical core-disruptive accident (HCDA). Bibliographic information on worldwide LMFBRs relative to the development of the breeder reactor as a safe source of nuclear power is presented for the period 1972 through 1974. The bibliography consists of approximately 1380 abstracts covering research and development and operating experiences leading up to the present design practices that are necessary for the licensing of breeder reactors. Key-word, author, and permuted-title indexes are included.

  13. Developing an Integrated Conceptual Framework of Pro-Environmental Behavior in the Workplace through Synthesis of the Current Literature

    Directory of Open Access Journals (Sweden)

    Faye V. McDonald

    2014-08-01

    Full Text Available Recent studies have begun to bridge the gap between general and workplace pro-environmental behavior by adapting specific existing behavioral models to the workplace environment. This conceptual article proposes a different approach by synthesizing the current general and workplace literature to develop a new model of the antecedents to pro-environmental behavior. Guided by this approach, this paper combines the insights of the current general and workplace models to develop an integrated framework of pro-environmental behavior in the workplace. In doing so, an overview of the current general and workplace literatures will be provided as well as their similarities and differences highlighted. The proposed framework will provide further insights into the antecedents of workplace pro-environmental behavior and identify common findings across the different existing workplace models. This theory can be the basis for further research in order to provide a comprehensive picture of the antecedents of pro-environmental behavior in the workplace. Lastly, implications for specific interventions to develop targeted Human Resource Management practices and work towards achieving environmental sustainability will be discussed.

  14. [Evaluation of scientific production in different subareas of Public Health: limits of the current model and contributions to the debate].

    Science.gov (United States)

    Iriart, Jorge Alberto Bernstein; Deslandes, Suely Ferreira; Martin, Denise; Camargo Jr, Kenneth Rochel de; Carvalho, Marilia Sá; Coeli, Cláudia Medina

    2015-10-01

    The aim of this study was to discuss the limits of the quantitative evaluation model for scientific production in Public Health. An analysis of the scientific production of professors from the various subareas of Public Health was performed for 2010-2012. Distributions of the mean annual score for professors were compared according to subareas. The study estimated the likelihood that 60% of the professors in the graduate studies programs scored P50 (Very Good) or higher in their area. Professors of Epidemiology showed a significantly higher median annual score. Graduate studies programs whose faculty included at least 60% of Epidemiology professors and fewer than 10% from the subarea Social and Human Sciences in Health were significantly more likely to achieve a "Very Good" classification. The observed inequalities in scientific production between different subareas of Public Health point to the need to rethink their evaluation in order to avoid reproducing iniquities that have harmful consequences for the field's diversity.

  15. Heat waves and morbidity: current knowledge and further direction-a comprehensive literature review.

    Science.gov (United States)

    Li, Mengmeng; Gu, Shaohua; Bi, Peng; Yang, Jun; Liu, Qiyong

    2015-05-18

    In the past few decades, several devastating heat wave events have significantly challenged public health. As these events are projected to increase in both severity and frequency in the future, it is important to assess the relationship between heat waves and the health indicators that can be used in the early warning systems to guide the public health response. Yet there is a knowledge gap in the impact of heat waves on morbidity. In this study, a comprehensive review was conducted to assess the relationship between heat waves and different morbidity indicators, and to identify the vulnerable populations. The PubMed and ScienceDirect database were used to retrieve published literature in English from 1985 to 2014 on the relationship between heat waves and morbidity, and the following MeSH terms and keywords were used: heat wave, heat wave, morbidity, hospital admission, hospitalization, emergency call, emergency medical services, and outpatient visit. Thirty-three studies were included in the final analysis. Most studies found a short-term negative health impact of heat waves on morbidity. The elderly, children, and males were more vulnerable during heat waves, and the medical care demand increased for those with existing chronic diseases. Some social factors, such as lower socioeconomic status, can contribute to heat-susceptibility. In terms of study methods and heat wave definitions, there remain inconsistencies and uncertainties. Relevant policies and guidelines need to be developed to protect vulnerable populations. Morbidity indicators should be adopted in heat wave early warning systems in order to guide the effective implementation of public health actions.

  16. Physician Scientist Training in the United States: A Survey of the Current Literature.

    Science.gov (United States)

    Kosik, R O; Tran, D T; Fan, Angela Pei-Chen; Mandell, G A; Tarng, D C; Hsu, H S; Chen, Y S; Su, T P; Wang, S J; Chiu, A W; Lee, C H; Hou, M C; Lee, F Y; Chen, W S; Chen, Q

    2016-03-01

    The declining number of physician scientists is an alarming issue. A systematic review of all existing programs described in the literature was performed, so as to highlight which programs may serve as the best models for the training of successful physician scientists. Multiple databases were searched, and 1,294 articles related to physician scientist training were identified. Preference was given to studies that looked at number of confirmed publications and/or research grants as primary outcomes. Thirteen programs were identified in nine studies. Eighty-three percent of Medical Scientist Training Program (MSTP) graduates, 77% of Clinician Investigator Training Program (CI) graduates, and only 16% of Medical Fellows Program graduates entered a career in academics. Seventy-eight percent of MSTP graduates succeeded in obtaining National Institute of Health (NIH) grants, while only 15% of Mayo Clinic National Research Service Award-T32 graduates obtained NIH grants. MSTP physician scientists who graduated in 1990 had 13.5 ± 12.5 publications, while MSTP physician scientists who graduated in 1975 had 51.2 ± 38.3 publications. Additionally, graduates from the Mayo Clinic's MD-PhD Program, the CI Program, and the NSRA Program had 18.2 ± 20.1, 26.5 ± 24.5, and 17.9 ± 26.3 publications, respectively. MSTP is a successful model for the training of physician scientists in the United States, but training at the postgraduate level also shows promising outcomes. An increase in the number of positions available for training at the postgraduate level should be considered.

  17. Improved cardiac function and exercise capacity following correction of pectus excavatum: a review of current literature.

    Science.gov (United States)

    Maagaard, Marie; Heiberg, Johan

    2016-09-01

    Patients with pectus excavatum (PE) often describe improvements in exercise stamina following corrective surgery. Studies have investigated the surgical effect on physiological parameters; still, no consensus has yet been reached. Therefore, the aim of this literature review was to describe the cardiac outcome after surgical correction, both at rest and during exercise. In February 2016, a detailed search of the databases PubMed, Medline, and EMBASE was performed. We assessed clinical studies that described cardiac outcomes both before and after surgical correction of PE. We only included studies reporting either pre-defined echocardiographic or exercise test parameters. No exclusion criteria or statistical analyses were applied. Twenty-one full-text articles, published between 1972 and 2016, were selected, with cohort-ranges of 3-168 patients, mean age-ranges of 5-33 years, and mean follow-up-ranges from immediately to 4 years after surgery. Twelve studies described resting cardiac parameters. Four studies measured cardiac output, where one described 36% immediate increase after surgery, one reported 15% increase after Nuss-bar removal and two found no difference. Three studies demonstrated improvement in mean stroke volume ranges of 22-34% and two studies found no difference. Fifteen studies investigated exercise capacity, with 11 considering peak O2 pr. kg, where five studies demonstrated improvements with the mean ranging from 8% to 15% after surgery, five studies demonstrated no difference, and one saw a decrease of 19% 3 months after Nuss-bar implantation. A measurable increase in exercise capacity exists following surgery, which may be caused by multiple factors. This may be owed to the relief of compressed cardiac chambers with the increased anterior-posterior thoracic dimensions, which could facilitate an improved filling of the heart. With these results, the positive physiological impact of the surgery is emphasized and the potential gain in cardiac

  18. A critical overview of the current myofascial pain literature - January 2016.

    Science.gov (United States)

    Dommerholt, Jan; Finnegan, Michelle; Grieve, Rob; Hooks, Todd

    2016-01-01

    Reflecting on the past year, the number of publications on myofascial pain continues to increase in a steady rate. The current review includes 30 basic and clinical studies, case reports, reviews, and reports from fifteen different countries about trigger points (TrP), myofascial pain (MP), dry needling (DN) and other related interventions. We are pleased that during 2015 this article made the top 15 of most downloaded articles as many as three times! In general, the quality of published papers is improving as well. Nevertheless, several papers included in this overview, mention the application of "ischemic compression", which is a questionable concept in the context of TrP inactivation. As we have outlined previously, in the current thinking about myofascial pain, TrPs feature significant hypoxia and a lowered pH (Ballyns et al., 2011; Shah and Gilliams, 2008), and attempts to induce more ischemia would be counterproductive. Already in 1999, Simons, Travell and Simons changed the terminology from ischemic compression to TrP compression (Simons et al., 1999) and we recommend that contemporary researchers and clinicians adopt the new terminology and stop using the term "ischemic compression."

  19. The impacts of trail infrastructure on vegetation and soils: Current literature and future directions.

    Science.gov (United States)

    Ballantyne, Mark; Pickering, Catherine Marina

    2015-12-01

    Reflecting the popularity of nature-based activities such as hiking and mountain biking, there are thousands of kilometres of recreational trails worldwide traversing a range of natural areas. These trails have environmental impacts on soils and vegetation, but where has there been research, what impacts have been found and how were they measured? Using a systematic quantitative literature review methodology, we assessed the impacts of trails on vegetation and soils, highlighting what is known, but also key knowledge gaps. Of the 59 original research papers identified on this topic that have been published in English language peer-reviewed academic journals, most were for research conducted in protected areas (71%), with few from developing countries (17%) or threatened ecosystems (14%). The research is concentrated in a few habitats and biodiversity hotspots, mainly temperate woodland, alpine grassland and Mediterranean habitats, often in the USA (32%) or Australia (20%). Most examined formal trails, with just 15% examining informal trails and 11% assessing both types. Nearly all papers report the results of observational surveys (90%), collecting quantitative data (66%) with 24% using geographic information systems. There was an emphasis on assessing trail impacts at a local scale, either on the trail itself and/or over short gradients away from the trail edge. Many assessed changes in composition and to some degree, structure, of vegetation and soils with the most common impacts documented including reduced vegetation cover, changes in plant species composition, trail widening, soil loss and soil compaction. There were 14 papers assessing how these local impacts can accumulate at the landscape scale. Few papers assessed differences in impacts among trails (7 papers), changes in impacts over time (4), species-specific responses (3) and only one assessed effects on plant community functioning. This review provides evidence that there are key research gaps

  20. A Systemic View of the Learning and Differentiation of Scientific Concepts: The Case of Electric Current and Voltage Revisited

    Science.gov (United States)

    Koponen, Ismo T.; Kokkonen, Tommi

    2014-01-01

    In learning conceptual knowledge in physics, a common problem is the incompleteness of a learning process, where students' personal, often undifferentiated concepts take on more scientific and differentiated form. With regard to such concept learning and differentiation, this study proposes a systemic view in which concepts are considered as…

  1. Transdermal delivery of combined hormonal contraception: a review of the current literature

    Directory of Open Access Journals (Sweden)

    Galzote RM

    2017-05-01

    Full Text Available Rosanna M Galzote,1 Sally Rafie,2 Rachel Teal,1 Sheila K Mody1 1Section of Family Planning, Department of Reproductive Medicine, University of California, San Diego, 2Department of Pharmacy, UC San Diego Health, San Diego, CA, USA Abstract: The transdermal patch provides an effective and convenient option for hormonal contraception. The patch currently on the US market contains 150 µg norelgestromin and 35 µg ethinylestradiol (EE. The 20 cm2 patch is applied once weekly for 3 weeks, followed by a patch-free week, for a 21–7 cycle. Typical failure rates are similar to that of combined oral contraceptives (COCs. Transdermal delivery results in less peaks and troughs of estrogen, but a higher total estrogen exposure compared with COCs. Though studies show mixed results, the risk of developing venous thromboembolism (VTE is about twice as high with the patch as with COCs; however, the absolute risk of VTE remains low. The side effect profile is similar to that of COCs, with slightly higher rates of breast tenderness plus a unique adverse effect of application site reactions. Two new patches have been developed, one containing gestodene and EE in Europe and another containing levonorgestrel and EE. Overall, the patch provides an alternative to COCs for women who want autonomy and the benefit of not needing to take a pill daily, with similar efficacy and tolerability. Keywords: contraceptive patch, Ortho-Evra, transdermal, levonorgestrel patch, gestodene patch, hormonal patch 

  2. Patient reported outcomes measures in neurogenic bladder and bowel: A systematic review of the current literature.

    Science.gov (United States)

    Patel, Darshan P; Elliott, Sean P; Stoffel, John T; Brant, William O; Hotaling, James M; Myers, Jeremy B

    2016-01-01

    To describe existing bladder and bowel specific quality of life (QoL) measurement tools, QoL in patients with multiple sclerosis (MS), spinal cord injury (SCI), Parkinson's Disease (PD), stroke, or spina bifida (SB) affected by bladder or bowel dysfunction, and the impact of specific bladder and bowel management on QoL. We performed a systematic review in PubMed/Medline databases in accordance with the PRISMA statement for English publications between January 1, 2000 and January 1, 2014. Articles were first screened based on their abstract and select full-text articles were then reviewed for eligibility. Articles with no QoL or PROM assessing urinary or bowel dysfunction were excluded. Risk of bias assessment included randomization, incomplete outcomes data, selective outcomes reporting, and other biases. All articles were graded using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) system as per the Cochrane Handbook for Systematic Reviews of Interventions. The most common QoL measurement tool for urinary and bowel dysfunction was the Medical Outcomes Study SF-36. Twelve (24%) studies used only non-validated QoL questionnaires. Only three urinary or bowel specific QoL measures were found: the Qualiveen questionnaire, the FICQoL, and the QoL-BM. Several studies identified instances were clinical and patient-reported outcomes were inconsistent particularly with indwelling urinary catheter usage and reconstructive surgery. Additionally, certain clinical outcomes surrogates commonly used as primary outcomes measures may not correlate with the patient reported outcomes (PRO). Current PRO measures (PROM) and QoL assessments are heterogeneous and several inconsistencies in clinical and PRO for various management options exist. Standardized PROM will help identify optimal bladder and bowel management for patients with neurologic conditions. © 2014 Wiley Periodicals, Inc.

  3. [Biomechanical aspects of load-bearing capacity after total endoprosthesis replacement of the hip joint. An evaluation of current knowledge and review of the literature].

    Science.gov (United States)

    Wirtz, D C; Heller, K D; Niethard, F U

    1998-01-01

    Purpose of the study was to summarize the current scientific knowledge of the interaction between rehabilitative procedures and the periprosthetic bone remodeling processes in the early postoperative phase of total hip arthroplasties. In a comprehensive review of the international literature we analysed the interdependence between osseointegration, primary implant stability, relative micromotion of implant versus bone, and joint loading forces during mobilisation or physiotherapy. Accordingly, guidelines for the rehabilitation of cemented as well as cementless hip arthroplasties were established in order to eliminate factors disturbing prosthetic integration and hence provide for the best long-term stability of the implanted prosthesis possible. Osseointegration of cementless implants is impossible if relative micromotions exceed > 150 microns. Furthermore, torsional stresses (i.e. alternate climbing of stairs, rising from seated position without arm support) will destabilize uncemented femoral shaft implants. Cemented prostheses may be loaded with full body weight. Uncemented implants should be loaded only partially for at least 6 weeks. Loadings of the hip joint with more than twice the body-weight (i.e. walking without crutches, physical exercise against high resistances or long levers) are to be avoided for 3 months. The transition from the three-points walking to the two-points walking technique depends particularly on the conditions of the muscles stabilizing the hip joint. The rehabilitation of patients after total hip arthroplasty has to be brought into line with the changed biomechanical situation, the particulars of the implants and the individual requirements of the patients.

  4. Specification of laboratory animal use in scientific articles: current low detail in the journals' instructions for authors and some proposals.

    Science.gov (United States)

    Alfaro, V

    2005-09-01

    The scientific article communicates results of research to other investigators; therefore, it must contain a complete description of the experiment to help other researchers when designing their future investigations. However, poorly detailed data on laboratory animal use is given in published articles. Despite the well-known and important contribution of the International Committee of Medical Journal Editors (ICMJE) to standardize scientific writing and submission of manuscripts to biomedical journals, no specific instructions on the reporting of animal use are given in the ICMJE Uniform Requirements and, therefore, most journals do not detail this to the authors. Individual efforts from groups like the Working Committee for the Biological Characterizations of Laboratory Animals, the Boyd Group, or the Committee on Publication Ethics are commendable. These contributions should be incorporated into the ICMJE Uniform Requirements and, later, into the Instructions for Authors of peer-reviewed journals. This would be the only efficient way to instruct authors on how to report laboratory animal use in their submitted manuscripts. The present article relates some proposals for helping authors when reporting animal use in scientific articles. These proposals are not only based on previous guidelines for animal specifications, but also on Instructions for Authors from journals specialized in Laboratory Animal Science. These proposals are classified into major and minor issues, and they are located in the corresponding parts of the article, as defined by the Introduction, Methods, Results, and Discussion (IMRAD) method. (c) 2005 Prous Science. All rights reserved.

  5. Scientific Crossbreeding

    DEFF Research Database (Denmark)

    Hvidtfeldt, Rolf

    This thesis presents an alternative approach to the analysis of interdisciplinarity. One of the basic reasons for developing an alternative method for evaluation of interdisciplinary activities is that epistemic issues are insufficiently dealt with in the existing literature on the topic. To deve......This thesis presents an alternative approach to the analysis of interdisciplinarity. One of the basic reasons for developing an alternative method for evaluation of interdisciplinary activities is that epistemic issues are insufficiently dealt with in the existing literature on the topic....... To develop a more adequate way of capturing what is at stake in interdisciplinarity, I suggest drawing inspiration from the contemporary philosophical literature on scientific representation. The development of a representation based approach to the analysis of interdisciplinarity, and the discussion...... of the concept of “scientific discipline” and disciplinary difference. This chapter provides reasons to assume that conventional scientific taxonomies do not provide a good basis for analysing epistemic aspects of interdisciplinary science. On this background it is argued that the concept of “approaches...

  6. Current Status and Future Prospects of Clinical Psychology: Toward a Scientifically Principled Approach to Mental and Behavioral Health Care.

    Science.gov (United States)

    Baker, Timothy B; McFall, Richard M; Shoham, Varda

    2008-11-01

    The escalating costs of health care and other recent trends have made health care decisions of great societal import, with decision-making responsibility often being transferred from practitioners to health economists, health plans, and insurers. Health care decision making increasingly is guided by evidence that a treatment is efficacious, effective-disseminable, cost-effective, and scientifically plausible. Under these conditions of heightened cost concerns and institutional-economic decision making, psychologists are losing the opportunity to play a leadership role in mental and behavioral health care: Other types of practitioners are providing an increasing proportion of delivered treatment, and the use of psychiatric medication has increased dramatically relative to the provision of psychological interventions. Research has shown that numerous psychological interventions are efficacious, effective, and cost-effective. However, these interventions are used infrequently with patients who would benefit from them, in part because clinical psychologists have not made a convincing case for the use of these interventions (e.g., by supplying the data that decision makers need to support implementation of such interventions) and because clinical psychologists do not themselves use these interventions even when given the opportunity to do so. Clinical psychologists' failure to achieve a more significant impact on clinical and public health may be traced to their deep ambivalence about the role of science and their lack of adequate science training, which leads them to value personal clinical experience over research evidence, use assessment practices that have dubious psychometric support, and not use the interventions for which there is the strongest evidence of efficacy. Clinical psychology resembles medicine at a point in its history when practitioners were operating in a largely prescientific manner. Prior to the scientific reform of medicine in the early 1900s

  7. ANALYSIS OF THE SCIENTIFIC LITERATURE OF THE POST-PALAEOLITHIC PAINTING IN SPAIN. LEVANTINE ART AND SCHEMATIC PAINTING (1907-2010

    Directory of Open Access Journals (Sweden)

    Miguel Ángel Mateo Saura

    2014-10-01

    Full Text Available Cave art constitutes one of the areas of study of prehistory more attractive, perhaps because of the secrecy that still conveys. After a century of research on post-Paleolithic cave painting in Spain, and when the scientific production exceeds two thousand records, is addressed from bibliometric parameters, the analysis of this production over the period 1907-2010. Based on an own database in Microsoft Access, prepared for over twenty years and that the March 31, 2011 counted on 2186 bibliographic records, bibliometric techniques are used to determine the temporal distribution, the language used, the styles of cave art, the document types, the themes addressed in the works and the publication place. Document production is below 21,02 publications/year until 1970, although in the 104 years of research analyzed, highlights the years 1999 (with 4,5% and 2006 (with 5,1% for the large number of publications. Regarding the language of the documents are distributed as follows, Spanish (88,1%, Catalan (4,6%, French (3,9%, English (2%, German (1% and other languages (Italian, Portuguese or Galician with 0,32%. 35,4% of production is dedicated to Levantine art, while schematic painting captures 34,8%. Regarding the document type, the scientific article stands out with 55,2%, followed by conference papers (19,2%, book chapters (11,3%, case studies (9,8%, notes (2,3%, doctoral thesis (1% and undergraduate dissertations (0,7%. The predominant topics are sites (34,5%, chronology (8,8%, iconography (7,7%, or scientific divulgation (5,1%. 90,6% of scientific production has been published in Spain, highlighting Zaragoza (13,4%, Madrid (13,3%, Valencia (9,2% and Murcia (9%. We consider that the total production is low because hardly exceeds 21 papers / year, although in the last fifty years growth rates were reached above 5%. Because Spanish is one of the most spoken languages in the world, greater internationalization of research of the Spanish post

  8. [Floods and public health: a review of the recent scientific literature on the causes, consequences and responses to prevention and mitigation].

    Science.gov (United States)

    de Freitas, Carlos Machado; Ximenes, Elisa Francioli

    2012-06-01

    Floods are among the most frequent natural disasters and they affect the lives of approximately 102 million people each year, mainly in developing countries and in major urban areas with a tendency to grow further over the coming decades. The scope of this paper is to provide input for a clearer understanding of these events through the results and experiences to be gleaned from the recent scientific literature. From the Pubmed database, 70 articles were analyzed that fulfilled the criteria to address at least one of the items selected for analysis, namely: 1) causes; 2) consequences; 3) responses and actions: submission of proposals and solutions for the prevention and/or mitigation of the risks and impacts of flooding. Tables for each of the items selected were organized in order to systematize and synthesize the results for causes (attributed to natural and human activities); environmental, infrastructure and services, and health consequences (injuries and diseases classified according to chapters of ICD-10); prevention and mitigation responses and actions. It was concluded that given the scenarios of increased frequency and severity of these events, the challenges facing public health for disaster risk reduction require integrated responses with broad policies for sustainable development.

  9. Risk factors and current recommendations for prevention of infections associated with central venous catheters: a literature review

    Directory of Open Access Journals (Sweden)

    Danielle de Mendonça Henrique

    2014-04-01

    Full Text Available Backgound and Objectives: Infections related to central venous catheter (CVC use constitute an important a problem. It is estimated that approximately 90% of bloodstream infections (BSI are caused by CVC use. This study aims at reviewing the risk factors and current recommendations for prevention of infections associated with central venous catheter use. Methods: A total of 12 articles published in the last 5 years and indexed in the databases of the Latin American and Caribbean Literature on Health Sciences (LILACS, Nursing Database (BDENF, International Literature on Health Sciences (Medline/Pubmed were selected, as well as publications related to the recommendations for BSI prevention, such as: Institute for Healthcare Improvement (IHI, Centers for Disease Control and Prevention (CDC and the National Health Surveillance Agency (ANVISA. Results: Two categories were identified: prevention and control measures and risk factors for BSI associated with central venous catheter use. Conclusions: Some recommendations that were well-defined over the years have been questioned by some authors and continuing training and education of the multidisciplinary team are the most important factors for the prevention of bloodstream infections associated with CVC use.

  10. Does high level youth sports participation increase the risk of femoroacetabular impingement? A review of the current literature.

    Science.gov (United States)

    de Silva, Viran; Swain, Michael; Broderick, Carolyn; McKay, Damien

    2016-03-11

    Sports participation can be an integral part of adolescent development with numerous positive short and long-term effects. Despite these potential benefits very high levels of physical activity, during skeletal maturation, have been proposed as a possible cause of cam-type femoroacetabular impingement (FAI). The influence of physical activity on the developing physis has been previously described both in animal studies and epidemiological studies of adolescent athletes. It is therefore important to determine whether the development of FAI is secondary to excessive physical activity or a combination of a vulnerable physis and a set level of physical activity. A review of the current literature suggests that adolescent males participating in ice-hockey, basketball and soccer, training at least three times a week, are at greater risk than their non-athletic counterparts of developing the femoral head-neck deformity associated with femoroacetabular impingement.

  11. Current state of musculoskeletal ultrasound training and implementation in Europe: results of a survey of experts and scientific societies

    DEFF Research Database (Denmark)

    Naredo, Esperanza; D'Agostino, Maria A; Conaghan, Philip G

    2010-01-01

    To document the current state of musculoskeletal US (MSUS) training and extent of implementation among rheumatologists in the member countries of EULAR.......To document the current state of musculoskeletal US (MSUS) training and extent of implementation among rheumatologists in the member countries of EULAR....

  12. A Qualitative Study Examining the Exclusive Use of Primary Literature in a Special Topics Biology Course: Improving Conceptions about the Nature of Science and Boosting Confidence in Approaching Original Scientific Research

    Science.gov (United States)

    Carter, B. Elijah; Wiles, Jason R.

    2017-01-01

    This qualitative study explores the experiences of six students enrolled in a special topics biology class that exclusively used primary literature as course material. Nature of science (NOS) conceptions have been linked to students' attitudes toward scientific subjects, but there has been little research specifically exploring the effects of…

  13. NASA/DoD Aerospace Knowledge Diffusion Research Project: Chronology of Selected Literature, Reports, Policy Instruments, and Significant Events Affecting Federal Scientific and Technical Information (STI) in the United States, 1945-1990. Report Number 11.

    Science.gov (United States)

    Pinelli, Thomas E.; And Others

    The chronology is a comprehensive bibliography covering a variety of selected literature, reports, policy instruments, and significant events affecting federal scientific and technical information (STI) from 1945 to 1990. It includes some publications and events of historic interest that relate to the evolution of aerospace and aerospace knowledge…

  14. Synopsis of Guidelines for the Clinical Management of Cerebral Cavernous Malformations: Consensus Recommendations Based on Systematic Literature Review by the Angioma Alliance Scientific Advisory Board Clinical Experts Panel.

    Science.gov (United States)

    Akers, Amy; Al-Shahi Salman, Rustam; A Awad, Issam; Dahlem, Kristen; Flemming, Kelly; Hart, Blaine; Kim, Helen; Jusue-Torres, Ignacio; Kondziolka, Douglas; Lee, Cornelia; Morrison, Leslie; Rigamonti, Daniele; Rebeiz, Tania; Tournier-Lasserve, Elisabeth; Waggoner, Darrel; Whitehead, Kevin

    2017-05-01

    Despite many publications about cerebral cavernous malformations (CCMs), controversy remains regarding diagnostic and management strategies. To develop guidelines for CCM management. The Angioma Alliance ( www.angioma.org ), the patient support group in the United States advocating on behalf of patients and research in CCM, convened a multidisciplinary writing group comprising expert CCM clinicians to help summarize the existing literature related to the clinical care of CCM, focusing on 5 topics: (1) epidemiology and natural history, (2) genetic testing and counseling, (3) diagnostic criteria and radiology standards, (4) neurosurgical considerations, and (5) neurological considerations. The group reviewed literature, rated evidence, developed recommendations, and established consensus, controversies, and knowledge gaps according to a prespecified protocol. Of 1270 publications published between January 1, 1983 and September 31, 2014, we selected 98 based on methodological criteria, and identified 38 additional recent or relevant publications. Topic authors used these publications to summarize current knowledge and arrive at 23 consensus management recommendations, which we rated by class (size of effect) and level (estimate of certainty) according to the American Heart Association/American Stroke Association criteria. No recommendation was level A (because of the absence of randomized controlled trials), 11 (48%) were level B, and 12 (52%) were level C. Recommendations were class I in 8 (35%), class II in 10 (43%), and class III in 5 (22%). Current evidence supports recommendations for the management of CCM, but their generally low levels and classes mandate further research to better inform clinical practice and update these recommendations. The complete recommendations document, including the criteria for selecting reference citations, a more detailed justification of the respective recommendations, and a summary of controversies and knowledge gaps, was

  15. A comunidade científica, o Estado e as universidades, no atual estágio de desenvolvimento científico tecnológico Scientific community, State and universities in the current stage of scientific technological development

    Directory of Open Access Journals (Sweden)

    Michelangelo Giotto Santoro Trigueiro

    2001-12-01

    Full Text Available O trabalho discute a relação entre a comunidade científica, o Estado e a universidade no contexto atual do desenvolvimento científico-tecnológico. Enfatiza a dimensão política das transformações recentes, sobretudo no tocante aos sistemas decisórios, contrapondo momento mais verticalizado com cenário mais democratizado, e as conseqüências das transformações políticas contemporâneas, na sociedade brasileira. Procura analisar as mútuas correlações entre o Estado, as universidades e as comunidades científicas, a partir do entendimento da especificidade de cada um destes atores na condução do desenvolvimento científico-tecnológico nacional. A esse respeito, é analisado todo um conjunto de ações que se coadunam com o novo modo de produção do conhecimento, buscando destacar a natureza controversa e polêmica da inserção do Estado e o caráter conservador da comunidade científica, bem como a resistência da universidade na proposição de novas linhas de atuação no enfrentamento dos desafios trazidos pela ciência e tecnologias contemporâneas.This article discusses the relationship between scientific community, the State and university in the current circumstances of scientific-technological development. It stresses the political dimension of recent changes, specially regarding decision systems, comparing a more vertical moment and a more democratic scenario and the consequences of contemporary political changes in Brazilian society. It examines mutual relations between the State, universities and the scientific community, based on the understanding of each of those actors' specificities in advancing national scientific-technological development. A whole set of actions is examined in accordance with knowledge's new mode of production in order to highlight the controversial nature of the State and the conservative character of the scientific community as well as the resistance of the university in proposing new lines

  16. Expanding the (kaleido)scope: exploring current literature trends for translating electroencephalography (EEG) based brain-computer interfaces for motor rehabilitation in children

    Science.gov (United States)

    Kinney-Lang, E.; Auyeung, B.; Escudero, J.

    2016-12-01

    Rehabilitation applications using brain-computer interfaces (BCI) have recently shown encouraging results for motor recovery. Effective BCI neurorehabilitation has been shown to exploit neuroplastic properties of the brain through mental imagery tasks. However, these applications and results are currently restricted to adults. A systematic search reveals there is essentially no literature describing motor rehabilitative BCI applications that use electroencephalograms (EEG) in children, despite advances in such applications with adults. Further inspection highlights limited literature pursuing research in the field, especially outside of neurofeedback paradigms. Then the question naturally arises, do current literature trends indicate that EEG based BCI motor rehabilitation applications could be translated to children? To provide further evidence beyond the available literature for this particular topic, we present an exploratory survey examining some of the indirect literature related to motor rehabilitation BCI in children. Our goal is to establish if evidence in the related literature supports research on this topic and if the related studies can help explain the dearth of current research in this area. The investigation found positive literature trends in the indirect studies which support translating these BCI applications to children and provide insight into potential pitfalls perhaps responsible for the limited literature. Careful consideration of these pitfalls in conjunction with support from the literature emphasize that fully realized motor rehabilitation BCI applications for children are feasible and would be beneficial. • BCI intervention has improved motor recovery in adult patients and offer supplementary rehabilitation options to patients. • A systematic literature search revealed that essentially no research has been conducted bringing motor rehabilitation BCI applications to children, despite advances in BCI. • Indirect studies discovered

  17. Are Metals Emitted from Electronic Cigarettes a Reason for Health Concern? A Risk-Assessment Analysis of Currently Available Literature

    Directory of Open Access Journals (Sweden)

    Konstantinos E. Farsalinos

    2015-05-01

    Full Text Available Background: Studies have found that metals are emitted to the electronic cigarette (EC aerosol. However, the potential health impact of exposure to such metals has not been adequately defined. The purpose of this study was to perform a risk assessment analysis, evaluating the exposure of electronic cigarette (EC users to metal emissions based on findings from the published literature. Methods: Two studies were found in the literature, measuring metals emitted to the aerosol from 13 EC products. We estimated that users take on average 600 EC puffs per day, but we evaluated the daily exposure from 1200 puffs. Estimates of exposure were compared with the chronic Permissible Daily Exposure (PDE from inhalational medications defined by the U.S. Pharmacopeia (cadmium, chromium, copper, lead and nickel, the Minimal Risk Level (MRL defined by the Agency for Toxic Substances and Disease Registry (manganese and the Recommended Exposure Limit (REL defined by the National Institute of Occupational Safety and Health (aluminum, barium, iron, tin, titanium, zinc and zirconium. Results: The average daily exposure from 13 EC products was 2.6 to 387 times lower than the safety cut-off point of PDEs, 325 times lower than the safety limit of MRL and 665 to 77,514 times lower than the safety cut-off point of RELs. Only one of the 13 products was found to result in exposure 10% higher than PDE for one metal (cadmium at the extreme daily use of 1200 puffs. Significant differences in emissions between products were observed. Conclusions: Based on currently available data, overall exposure to metals from EC use is not expected to be of significant health concern for smokers switching to EC use, but is an unnecessary source of exposure for never-smokers. Metal analysis should be expanded to more products and exposure can be further reduced through improvements in product quality and appropriate choice of materials.

  18. A review of the scientific literature related to the adverse impact of physical restraint: gaining a clearer understanding of the physiological factors involved in cases of restraint-related death.

    Science.gov (United States)

    Barnett, Richard; Stirling, Chris; Pandyan, Anand D

    2012-07-01

    Deaths occurring during and/or in close proximity to physical restraint have been attributed to positional asphyxia, a conclusion primarily based on opinion and reviews of case studies. This review sought to identify the current scientific evidence available in regard to the aetiology of adverse events or death occurring during or in close proximity to physical restraint. A systematic search of electronic databases (SPORTDiscus, AMED, CINAHL, MEDLINE, PsycINFO) for papers published in English, between 1980 and 2011, using keywords that related to restraint, restraint position and cardiovascular function resulted in 11 experimental papers being found for review. The term positional asphyxia as a mechanism for sudden death is poorly understood. The literature shows that restraint position has the ability to impede life-maintaining physiological functions, but that the imposed impediment is not uniform across all restraint positions/techniques. Further research is required to ascertain the risks posed by struggling during restraint for more prolonged periods of time and in different positions using varied techniques of restraint. This research should seek to and rank known or future risk factors of adverse events occurring during restraint, seeking to understand the interactions and if present the cumulative effect of these risk factors. Finally, future research should focus on populations other than apparently healthy male adults.

  19. Educational interventions to advance children's scientific thinking.

    Science.gov (United States)

    Klahr, David; Zimmerman, Corinne; Jirout, Jamie

    2011-08-19

    The goal of science education interventions is to nurture, enrich, and sustain children's natural and spontaneous interest in scientific knowledge and procedures. We present taxonomy for classifying different types of research on scientific thinking from the perspective of cognitive development and associated attempts to teach science. We summarize the literature on the early--unschooled--development of scientific thinking, and then focus on recent research on how best to teach science to children from preschool to middle school. We summarize some of the current disagreements in the field of science education and offer some suggestions on ways to continue to advance the science of science instruction.

  20. Current Scientific Impact of Ss Cyril and Methodius University of Skopje, Republic of Macedonia in the Scopus Database (1960-2014)

    OpenAIRE

    2015-01-01

    Aim: The aim of this study was to analyze current scientific impact of Ss Cyril and Methodius University of Skopje, Republic of Macedonia in the Scopus Database (1960-2014). Material and Methods: Affiliation search of the Scopus database was performed on November 23, 2014 in order to identify published papers from the Ss Cyril and Methodius University of Skopje (UC&M), Republic of Macedonia. A total number of 3960 articles (3055 articles from UC&M, 861 articles from Faculty of Medicine, U...

  1. Design of an Experimental Contemporary Physics Course which Develops the Full Experience of Scientific Research and Highlights Current Faculty Research

    Science.gov (United States)

    Yarrison-Rice, Jan M.; Jaeger, Herbert; Eid, Khalid F.

    2013-03-01

    From background literature searches and reading, to conducting experiments, to presenting results and writing a journal manuscript, Miami University has revised its second-year Experimental Contemporary Physics Course, Phy293, to follow a basic research model. We examined research that faculty were conducting and chose experiments which were strongly related to understanding the ongoing research in the Department, while being based in fundamental quantum mechanics and recent 21st century physics. Experiments often had common instrumentation and data analysis techniques which allowed for grouping them into 3 basic categories: 1) Spectroscopy of gases and solids, 2) Characterization of contemporary samples, and 3) Quantized systems in electronic, magnetic and nuclear physics. These experiments also supported our secondary goal of preparing students to enter our research laboratories. At Miami, we generally have between 25-35 second year students, so the laboratory course must be managed to maintain groups of 2-3 for the best student learning outcomes. We will report on course logistics, the grouping of experiments, and methods for assessing students' learning. Having run the revised, full experimental format of Phy293 a 3rd time, we feel confident stating that this course demonstrates to students ``how physics research in the 21st century is actually conducted!''

  2. Current Situation of Published SCI Paper in Traditional Chinese Medicine Scientific Research in Stitutes%我国中医药科研单位发表SCI论文现状分析

    Institute of Scientific and Technical Information of China (English)

    刘学俊; 陈玉龙

    2012-01-01

    目的:分析我国中医药科研机构发表SCI论文情况.方法:利用ISI Web of Knowledge数据库进行了检索,从学科类别、文献类别、研究机构、发表年份、出版物、引文等方面进行了分析.结果:我国中医药科研机构发表的SCI论文逐年增多,中药学相关论文数目明显多于中医学相关论文,发表在中国大陆出版的期刊比例较重,论文引用率相对较低.结论:我国中医药科研单位发表的SCI论文数量增长迅速,但仍有发展空间,质量亟待提高,中药与中医相关论文发展呈不平衡态势.%Objective: Analyze the current situation of published SCI paper in traditional Chinese medicine scientific research institutes. Methods:Use the ISI Web of Knowledge database to analyze from the subject category,literature type,research institutions,published year,publications,citations and so on. Results:SCI paper published in the Chinese medicine scientific research institutions increase annually , Chinese medicine related significantly more than traditional Chinese medicine related and more published in the journal published in Chinese mainland with low quoted rate. Conclusion: Published SCI paper in the traditional Chinese medicine scientific research institutes increases rapidly,but still need development and improvement. The development of Chinese medicine and traditional Chinese medicine development related thesis shows imbalance.

  3. ¹H magnetic resonance spectroscopy: a review of the current literature and its potential utility in veterinary oncology.

    Science.gov (United States)

    Lynch, Katherine; O'Brien, Robert

    2014-05-01

    Advanced imaging of veterinary cancer patients has evolved in recent years and modalities once limited to human medicine have now been described for diagnostic purposes in veterinary medicine (positron emission tomography/computed tomography, single-photon emission computed tomography, whole body magnetic resonance imaging). Magnetic resonance spectroscopy (MRS) is a non-invasive and non-ionizing technique that is well described in the human medical literature and is most frequently used to evaluate the metabolic activity of tissues with questionable malignant transformation. Differentiation of neoplastic tissue from surrounding normal tissue is dependent on variations in cellular metabolism. Positive identification of malignancy can be made when neoplastic alterations are occurring at the cellular level prior to gross anatomic changes. This improved, early detection of cancer occurrence (or recurrence) can improve patient survival and direct medical therapy. MRS techniques are largely underutilized in veterinary medicine, with current research predominantly limited to the brain (both evaluation of normal and diseased tissue). Given the clinical utility of MRS in humans, the technique may also be useful in the staging of cancer in veterinary medicine.

  4. Hyperbaric oxygen therapy in the treatment of osteonecrosis of the femoral head: a review of the current literature.

    Science.gov (United States)

    Uzun, Gunalp; Mutluoglu, Mesut; Ersen, Omer; Yildiz, Senol

    2016-01-01

    To review the current literature on the use of hyperbaric oxygen (HBO₂) therapy in the treatment of osteonecrosis of the femoral head (ONFH). We searched PubMed, Directory of Open Access Journals (DOAJ), EMBASE, Web of Science, Academic Search Complete, CINAHL and MEDLINE through April 2015. We hand-searched relevant textbooks, conference proceedings and the reference lists of review articles and clinical studies Randomized controlled trials (RCT) and observational studies (cohort study, case-control study, case series) that reported the outcome of patients who received HBO₂therapy for ONFH were included. Only English-language articles were included. Study quality was not used as an exclusion criterion. Two authors independently assessed trials for inclusion, extracted data and presented to other authors. Disagreements were resolved by consensus. We identified eight clinical studies; two randomized controlled trials (RCTs); one historically controlled study; and five case series. The majority of the studies were small-scale, heterogeneous and methodologically weak. In four of the studies HBO₂therapy was combined with other treatment modalities, making it impossible to draw firm conclusions on the specific effects of HBO₂therapy. Hip survivorship in studies wherein HBO₂therapy was used alone was 95.5% in Steinberg Stage I lesions, 89% in Steinberg Stage II lesions and 100% in Ficat Stage II lesions. There is a room for HBO₂therapy in the management ONFH. Further RCTs, however, are required to better elucidate the role of HBO₂therapy in the treatment of ONFH.

  5. A Writing-Intensive Course Improves Biology Undergraduates' Perception and Confidence of Their Abilities to Read Scientific Literature and Communicate Science

    Science.gov (United States)

    Brownell, Sara E.; Price, Jordan V.; Steinman, Lawrence

    2013-01-01

    Most scientists agree that comprehension of primary scientific papers and communication of scientific concepts are two of the most important skills that we can teach, but few undergraduate biology courses make these explicit course goals. We designed an undergraduate neuroimmunology course that uses a writing-intensive format. Using a mixture of…

  6. 文学创作品牌的当下构建%Current Construction of Literature Creation Brand

    Institute of Scientific and Technical Information of China (English)

    方伟

    2011-01-01

    realization of the actual results and the possible problems must be examined and tracked,the value of literary creation brand construction,will play a more and more obvious,more and more important and more and more indispensable role in the current and future literature survival and development.

  7. Collation of Scientific Evidence on Consumer Acceptance of New Food Technologies: Three roads to consumer choice

    NARCIS (Netherlands)

    Fischer, A.R.H.; Trijp, van J.C.M.; Hofenk, D.J.B.; Ronteltap, A.; Tudoran, A.A.

    2012-01-01

    The current report investigates consumer acceptance of new food technologies by reviewing the scientific literature. The review is organised along three routes to consumer acceptance of new technologies: The consumer benefit road: the central road of technology features influencing experienced

  8. Preventive fluid and dietary therapy for urolithiasis: An appraisal of strength, controversies and lacunae of current literature.

    Science.gov (United States)

    Agarwal, Mayank Mohan; Singh, Shwaran K; Mavuduru, Ravimohan; Mandal, Arup K

    2011-07-01

    Regulation of fluid and dietary intake habits is essential in comprehensive preventive management of urolithiasis. However, despite large body of epidemiological database, there is dearth of good quality prospective interventional studies in this regard. Often there is conflict in pathophysiological basis and actual clinical outcome. We describe conflicts, controversies and lacunae in current literature in fluid and dietary modifications in prevention of urolithiasis. Adequate fluid intake is the most important conservative strategy in urolithiasis-prevention; its positive effects are seen even at low volumes. Of the citrus, orange provides the most favorable pH changes in the urine, equivalent to therapeutic alkaline citrates. Despite being richest source of citrate, lemon does not increase pH significant due to its acidic nature. Fructose, animal proteins and fats are implicated in contributing to obesity, which is an established risk factor for urolithiasis. Fructose and proteins also contribute to lithogenecity of urine directly. Sodium restriction is commonly advised since natriuresis is associated with calciuresis. Calcium restriction is not advisable for urolithiasis prevention. Adequate calcium intake is beneficial if taken with food since it reduces absorption of dietary oxalate. Increasing dietary fiber does not protect against urolithiasis. Evidence for pyridoxine and magnesium is not robust. There is no prospective interventional study evaluating effect of many dietary elements, including citrus juices, carbohydrate, fat, dietary fiber, sodium, etc. Due to lack of good-quality prospective interventional trials it is essential to test the findings of pathophysiological understanding and epidemiological evidence. Role of probiotics and phytoceuticals needs special attention for future research.

  9. Genetic and epigenetic changes in vulvar squamous cell carcinoma and its precursor lesions: a review of the current literature.

    Science.gov (United States)

    Trietsch, Marjolijn D; Nooij, Linda S; Gaarenstroom, Katja N; van Poelgeest, Mariette I E

    2015-01-01

    Vulvar cancer is a relatively rare gynecologic malignancy with an annual incidence in developed countries of approximately 2 per 100,000 women. Vulvar squamous cell carcinoma (VSCC) has two etiological pathways: a high risk human papillomavirus (HPV)-dependent route, which has usual vulvar intraepithelial neoplasia (uVIN) as a precursor lesion, and an HPV-independent route, which is associated with differentiated VIN (dVIN), lichen sclerosus, and genetic alterations, such as TP53 mutations. Research on the molecular etiology of vulvar cancer has increased in the past years, not only regarding genetic alterations, but also epigenetic changes. In genetic alterations, a mutation irreversibly changes the nucleotide sequence of the DNA, or the number of copies of chromosomes per cell is altered. In epigenetics, the nucleotide sequence remains the same but genes can be 'switched' on or off by, for example, DNA methylation or histone modification. We searched the current literature on genetic and epigenetic alterations in VSCC and its precursor lesions. Many studies have reported a higher incidence of somatic mutations in HPV-negative tumors compared to HPV-positive tumors, with TP53 mutations being the most frequent. Allelic imbalances or loss of heterozygosity are more frequently found in higher stages of dysplasia and in invasive carcinomas, but it is not exclusive to HPV-negative tumors. A limited number of studies are available on epigenetic changes in vulvar lesions, with hypermethylation of CDKN2A being the most frequently investigated change. For most genes, hypermethylation occurs more frequently in vulvar squamous cell carcinomas than in precursor lesions. As most studies have focused on HPV infection and TP53 mutations, we suggest that more research should be performed using whole genome or next generation sequencing to determine the true landscape of genetic and epigenetic alterations in vulvar squamous cell carcinoma.

  10. Preventive fluid and dietary therapy for urolithiasis: An appraisal of strength, controversies and lacunae of current literature

    Directory of Open Access Journals (Sweden)

    Mayank Mohan Agarwal

    2011-01-01

    Full Text Available Regulation of fluid and dietary intake habits is essential in comprehensive preventive management of urolithiasis. However, despite large body of epidemiological database, there is dearth of good quality prospective interventional studies in this regard. Often there is conflict in pathophysiological basis and actual clinical outcome. We describe conflicts, controversies and lacunae in current literature in fluid and dietary modifications in prevention of urolithiasis. Adequate fluid intake is the most important conservative strategy in urolithiasis-prevention; its positive effects are seen even at low volumes. Of the citrus, orange provides the most favorable pH changes in the urine, equivalent to therapeutic alkaline citrates. Despite being richest source of citrate, lemon does not increase pH significant due to its acidic nature. Fructose, animal proteins and fats are implicated in contributing to obesity, which is an established risk factor for urolithiasis. Fructose and proteins also contribute to lithogenecity of urine directly. Sodium restriction is commonly advised since natriuresis is associated with calciuresis. Calcium restriction is not advisable for urolithiasis prevention. Adequate calcium intake is beneficial if taken with food since it reduces absorption of dietary oxalate. Increasing dietary fiber does not protect against urolithiasis. Evidence for pyridoxine and magnesium is not robust. There is no prospective interventional study evaluating effect of many dietary elements, including citrus juices, carbohydrate, fat, dietary fiber, sodium, etc. Due to lack of good-quality prospective interventional trials it is essential to test the findings of pathophysiological understanding and epidemiological evidence. Role of probiotics and phytoceuticals needs special attention for future research.

  11. Features of a Mobile Support App for Patients With Chronic Obstructive Pulmonary Disease: Literature Review and Current Applications

    Science.gov (United States)

    Philip, Nada; Kayyali, Reem; Nabhani-Gebara, Shereen; Pierscionek, Barbara; Vaes, Anouk W; Spruit, Martijn A; Kaimakamis, Evangelos

    2017-01-01

    Background Chronic obstructive pulmonary disease (COPD) is a serious long-term lung disease in which the airflow from the lungs is progressively reduced. By 2030, COPD will become the third cause of mortality and seventh cause of morbidity worldwide. With advances in technology and mobile communications, significant progress in the mobile health (mHealth) sector has been recently observed. Mobile phones with app capabilities (smartphones) are now considered as potential media for the self-management of certain types of diseases such as asthma, cancer, COPD, or cardiovascular diseases. While many mobile apps for patients with COPD are currently found on the market, there is little published material on the effectiveness of most of them, their features, and their adoption in health care settings. Objectives The aim of this study was to search the literature for current systems related to COPD and identify any missing links and studies that were carried out to evaluate the effectiveness of COPD mobile apps. In addition, we reviewed existing mHealth apps from different stores in order to identify features that can be considered in the initial design of a COPD support tool to improve health care services and patient outcomes. Methods In total, 206 articles related to COPD management systems were identified from different databases. Irrelevant materials and duplicates were excluded. Of those, 38 articles were reviewed to extract important features. We identified 214 apps from online stores. Following exclusion of irrelevant apps, 48 were selected and 20 of them were downloaded to review some of their common features. Results Our review found that out of the 20 apps downloaded, 13 (65%, 13/20) had an education section, 5 (25%, 5/20) consisted of medication and guidelines, 6 (30%, 6/20) included a calendar or diary and other features such as reminders or symptom tracking. There was little published material on the effectiveness of the identified COPD apps. Features such as

  12. ANALYSIS OF THE SCIENTIFIC LITERATURE OF THE POST-PALAEOLITHIC PAINTING IN SPAIN. LEVANTINE ART AND SCHEMATIC PAINTING (1907-2010)

    National Research Council Canada - National Science Library

    Miguel Ángel Mateo Saura; Isidoro Gil-Leiva; Antonio Pulgarín-Guerrero

    2014-01-01

    .... After a century of research on post-Paleolithic cave painting in Spain, and when the scientific production exceeds two thousand records, is addressed from bibliometric parameters, the analysis...

  13. Rediscovering the scientific ethos

    DEFF Research Database (Denmark)

    Djørup, Stine

    The doctoral dissertation discusses some of the moral standards of good scientific practice that areunderexposed in the literature. In particular, attempts are made to correct the conceptual confusionsurrounding the norm of 'disinterestedness' in science (‘uhildethed’), and the norm of scientific...

  14. Audiologia do envelhecimento: revisão da literatura e perspectivas atuais Audiology and aging: literature review and current horizons

    Directory of Open Access Journals (Sweden)

    Renato Peixoto Veras

    2007-02-01

    Full Text Available OBJETIVO: Revisar a literatura sobre a perda auditiva associada ao envelhecimento e suas implicações, numa perspectiva atual. REVISÃO DA LITERATURA: Nos estudos realizados no Brasil, a presbiacusia vem sendo apontada como causa mais freqüente da deficiência auditiva em pessoas idosas, implicando em uma dificuldade de compreensão durante a comunicação verbal. Estudos internacionais também mostram alta prevalência da perda auditiva em pessoas idosas. DISCUSSÃO: Segundo pesquisas recentes, à medida que o quantitativo da população idosa vem aumentando, também aumenta a prevalência da presbiacusia que interfere na qualidade de vida do idoso. Mesmo entre os profissionais de saúde, ainda é grande o desconhecimento em relação às vantagens e ganhos que a reeducação auditiva específica para idosos com perda auditiva pode oferecer. CONCLUSÃO: Os artigos aqui analisados mostraram que os serviços de saúde da rede pública, que envolvem médicos e fonoaudiólogos, devem estabelecer diretrizes para o desenvolvimento de programas de diagnóstico, aquisição de aparelhos de amplificação sonora individual e, principalmente, de reeducação auditiva para os idosos portadores de presbiacusia, para que eles possam participar e desfrutar das relações sociais, mantendo uma boa qualidade de vida. Entretanto, no Brasil, os estudos e pesquisas nesta área estão apenas começando.AIM: to review the literature on aging-related hearing loss and its current impacts. LITERATURE REVIEW: In studies carried out in Brazil, presbycusis has been blamed for being the most frequent cause of hearing loss in the elderly, causing verbal communication impairment. International studies also show the high prevalence of hearing loss in the elderly. DISCUSSION: According to recent investigations, as the number of elderly people increase, the prevalence of presbycusis interfering in the life quality of this population also increases. Even among health care

  15. Rehabilitation Engineering & Assistive Technology Society (RESNA) position on the application of wheelchair standing devices: 2013 current state of the literature.

    Science.gov (United States)

    Dicianno, Brad E; Morgan, Amy; Lieberman, Jenny; Rosen, Lauren

    2016-01-01

    This article, approved by the Rehabilitation Engineering & Assistive Technology Society of North America Board of Directors on December 23, 2013, shares typical clinical applications and provides evidence from the literature supporting the use of wheelchair standers.

  16. A systematic literature review of the current trends and challenges of internationalization of higher education in Latin America

    OpenAIRE

    Gómez Brand, María Fernanda

    2015-01-01

    This paper aims to consolidate a sample of existing academic literature on the modes, trends, risks and challenges of the internationalization of higher education in Latin America published over the last 15 years -- Following a systematic literature review methodology, it was seeking to analyze and synthesize a sample of 25 published academic articles on the specifically chosen topic -- As a consequence of this review, it was found that progress has been made on the subject and there is an aw...

  17. Considerations on Tatczëzna. Literackie przestrzenie Kaszub by Adela Kuik-Kalinowska and Current Studies on Kashubian Literature

    Directory of Open Access Journals (Sweden)

    Tomasz Derlatka

    2014-03-01

    Full Text Available The main objective of the authoress of the monograph Tatczëzna. Literackie przestrzenie Kaszub (Tatczëzna. Literary Spaces of Kashubia is to elaborate and present the anthropological outline of the Kashubian literature. He focuses on selected (anthropological points of reference, i.e. leading motives in the Kashubian culture/literature. They are, on the one hand, childhood, femininity, masculinity, and on the other hand, the values which are fundamentally related to the spiritual culture of Kashubia: the native land (tatczëzna, rodnô zemia and the Kashubian language (rodnô mòwa. Presentation of these motifs occurs in the cultural conditions of Polish tradition. The anthropological outline of the Kashubian literature is presented by Kuik-Kalinowska from two perspectives: in the “local” plane, i.e. in the context of social and cultural phenomena specific only for the Kashubian culture, and in a more general context, by emphasizing its universal aspects. Both perspectives are to show both what in the Kashubian culture and literature is regional, ethnic, own, as well as what is universal, of a general character, often unconscious to the writers. According to the researcher, the variety of themes and motifs of the Kashubian literature indicates its maturity and artistic self-sufficiency, and this puts it on an equal grounds with other literatures.

  18. Implementing a Grant Proposal Writing Exercise in Undergraduate Science Courses to Incorporate Real-World Applications and Critical Analysis of Current Literature

    Science.gov (United States)

    Cole, Kathryn E.; Inada, Maki; Smith, Andrew M.; Haaf, Michael P.

    2013-01-01

    Writing is an essential part of a successful career in science. As such, many undergraduate science courses have begun to implement writing assignments that reflect "real-world" applications and focus on a critical analysis of current literature; these assignments are often in the form of a review or a research proposal. The…

  19. Art, Meet Chemistry; Chemistry, Meet Art: Case Studies, Current Literature, and Instrumental Methods Combined to Create a Hands-On Experience for Nonmajors and Instrumental Analysis Students

    Science.gov (United States)

    Nivens, Delana A.; Padgett, Clifford W.; Chase, Jeffery M.; Verges, Katie J.; Jamieson, Deborah S.

    2010-01-01

    Case studies and current literature are combined with spectroscopic analysis to provide a unique chemistry experience for art history students and to provide a unique inquiry-based laboratory experiment for analytical chemistry students. The XRF analysis method was used to demonstrate to nonscience majors (art history students) a powerful…

  20. A structured literature review of the burden of illness and unmet needs in patients with rheumatoid arthritis: a current perspective.

    Science.gov (United States)

    Taylor, Peter C; Moore, Adam; Vasilescu, Radu; Alvir, Jose; Tarallo, Miriam

    2016-05-01

    While rheumatologists often focus on treatment targets, for many patients with rheumatoid arthritis (RA), control over pain and fatigue, as well as sustaining physical function and quality of life (QoL), is of primary importance. This literature review aimed at examining patients' and physicians' treatment aspirations, and identifying the unmet needs for patients with RA receiving ongoing treatment. Searches were performed using MEDLINE, Embase, PsycINFO, and Econlit literature databases for articles published from 2004 to 2014 in the English language. Published literature was screened to identify articles reporting the unmet needs in RA. We found that, despite the wide range of available treatments, RA continues to pose a substantial humanistic and economic burden on patients, and there are still unmet needs across key domains such as pain, physical function, mental function, and fatigue. These findings suggest that there is a need for further treatment advances in RA that address these domains of contemporary unmet need.

  1. Grey Literature 2.0

    OpenAIRE

    Simandlová, Tereza

    2012-01-01

    The paper tries to describe grey literature in the context of platforms and tools of the web 2.0. We can follow up that increasing trends in the scientific communication are e.g. microblogging, scientific blogging and there are also scientific social networks in the distribution cycle of grey literature. Except the examples of grey literature 2.0, the paper also discusses the problems of the promotion of grey literature and grey literature community through the social media.

  2. Development Methods Analysis of Scientific and Technological Literature Service in Big Data Era%大数据时代科技文献服务发展路径研究

    Institute of Scientific and Technical Information of China (English)

    张宏峰; 张敏; 段炼

    2015-01-01

    大数据是继云计算、物联网之后IT产业又一次颠覆性的技术革命,大数据挖掘和应用可创造出超万亿美元的价值。大数据时代的来临对文献服务也提出了更高的要求。本文从科技文献服务面临的困境、大数据时代的机遇与挑战、科技文献服务转型与升级三个方面来阐述。%Big data is a disruptive technology revolution after the cloud computing and Internet of things in IT industry. The exploitation and application of big data can create a value of super trillion dollars. The coming of big data era also puts forward higher requirements on literature service. This article interprets from three perspectives of difficulties faced by scientific and technological literature service, opportunities and challenges in big data era, and the transformation and upgrading of scientific and technological literature service.

  3. Social scientific environmental research in Finland. An overview on the research fields and literature; Yhteiskuntatieteellinen ympaeristoetutkimus Suomessa. Katsaus tutkimusaloihin ja kirjallisuuteen

    Energy Technology Data Exchange (ETDEWEB)

    Viinikainen, T. [ed.

    1997-12-31

    This report presents an overview on Finnish social scientific research on the environment. This research field studies the interaction between man and nature, as well as the causes, solutions and effects of environmental problems, in their social context. Research activities in the field have increased in Finland in the 1990`s. In the resort the following research areas are shortly described: environmental history, environmental philosophy and theology, environmental sociology, environmental research in communication studies, research on environmental politics, economics, geography and urban planning, environmental education, environmental law, and forestry. In each research field the latest projects in different research institutions are also listed. In addition to this, the report contains a bibliography on Finnish social scientific research on the environment between the years 1990 and 1996. (orig.) 98 refs.

  4. Network effects on scientific collaborations.

    Directory of Open Access Journals (Sweden)

    Shahadat Uddin

    Full Text Available BACKGROUND: The analysis of co-authorship network aims at exploring the impact of network structure on the outcome of scientific collaborations and research publications. However, little is known about what network properties are associated with authors who have increased number of joint publications and are being cited highly. METHODOLOGY/PRINCIPAL FINDINGS: Measures of social network analysis, for example network centrality and tie strength, have been utilized extensively in current co-authorship literature to explore different behavioural patterns of co-authorship networks. Using three SNA measures (i.e., degree centrality, closeness centrality and betweenness centrality, we explore scientific collaboration networks to understand factors influencing performance (i.e., citation count and formation (tie strength between authors of such networks. A citation count is the number of times an article is cited by other articles. We use co-authorship dataset of the research field of 'steel structure' for the year 2005 to 2009. To measure the strength of scientific collaboration between two authors, we consider the number of articles co-authored by them. In this study, we examine how citation count of a scientific publication is influenced by different centrality measures of its co-author(s in a co-authorship network. We further analyze the impact of the network positions of authors on the strength of their scientific collaborations. We use both correlation and regression methods for data analysis leading to statistical validation. We identify that citation count of a research article is positively correlated with the degree centrality and betweenness centrality values of its co-author(s. Also, we reveal that degree centrality and betweenness centrality values of authors in a co-authorship network are positively correlated with the strength of their scientific collaborations. CONCLUSIONS/SIGNIFICANCE: Authors' network positions in co

  5. Current status on behavioral and biological markers of PTSD: a search for clarity in a conflicting literature.

    Science.gov (United States)

    Zoladz, Phillip R; Diamond, David M

    2013-06-01

    Extensive research has identified stereotypic behavioral and biological abnormalities in post-traumatic stress disorder (PTSD), such as heightened autonomic activity, an exaggerated startle response, reduced basal cortisol levels and cognitive impairments. We have reviewed primary research in this area, noting that factors involved in the susceptibility and expression of PTSD symptoms are more complex and heterogeneous than is commonly stated, with extensive findings which are inconsistent with the stereotypic behavioral and biological profile of the PTSD patient. A thorough assessment of the literature indicates that interactions among myriad susceptibility factors, including social support, early life stress, sex, age, peri- and post-traumatic dissociation, cognitive appraisal of trauma, neuroendocrine abnormalities and gene polymorphisms, in conjunction with the inconsistent expression of the disorder across studies, confounds attempts to characterize PTSD as a monolithic disorder. Overall, our assessment of the literature addresses the great challenge in developing a behavioral and biomarker-based diagnosis of PTSD. Published by Elsevier Ltd.

  6. NASA/DOD Aerospace Knowledge Diffusion Research Project. Report 11: Chronology of selected literature, reports, policy instruments, and significant events affecting Federal Scientific and Technical Information (STI) in the United States

    Science.gov (United States)

    Pinelli, Thomas E.; Henderson, Madeline; Bishop, Ann P.; Doty, Philip

    1992-01-01

    The chronology is a comprehensive bibliography. It contains 512 entries covering a variety of selected literature, reports, policy instruments, and significant events affecting Federal Scientific and Technical Information (STI) from 1945 to 1990. It includes some publications and events of historic interest which relate to the evaluation of aerospace and aerospace knowledge diffusion. Each entry has been given an item number and items are arranged by columns. To provide an overview of Federal STI developments, the entries are generally arranged by date of publication and event.

  7. 临床护理和护理科研中Meta分析法应用现状的文献分析%Current application of meta-analysis in clinical nursing and nursing scientific research in China

    Institute of Scientific and Technical Information of China (English)

    常婷; 赵婷; 陶学梅; 潘凌蕴

    2013-01-01

    目的 对近10年Meta分析法在国内护理临床和科研中的应用现状进行研究.方法 采用计算机检索和手工检索相结合的方法,检索2003年1月至2013年1月万方数据资源系统、中国知网(CNKI)、中文科技期刊数据库(VIP)、中文生物医学期刊数据库(CMCC)收录的国内所有涉及护理临床和科研应用的Meta分析文章,2位评估者独立提取数据,应用OQAQ量表进行质量评价.结果 纳入21篇合格文献,其中专科护理实践16篇,护理教育5篇.纳入文献中,资料检索和缺乏研究真实性评价是主要缺陷.结论 应用Meta分析可以汇总同类护理研究的不同研究结果,目前许多护理领域Meta分析的应用仍是空白,护理工作可以应用这种分析方法提高护理学科研水平.%Objective To understand current application of meta-analysis in clinical nursing and nursing scientific research in China in recent ten years.Methods The literature which concerned application of meta-analysis in clinical nursing and nursing scientific research in China in recent ten years,and was published in January 2003 through January 2013,were retrieved from Wanfang Database,CNKI,VIP,CMCC manually or through computer aided methods.Two researchers extracted data independently and assessed the quality of the included literature with the Oxman-Guyatt Overview Quality Assessment Questionnaire (OQAQ).Results Twenty-one papers met the inclusion and exclusion criteria,with 16 papers concerning specialized advanced nursing practice,the others concerning nursing education.The major defects of the included literature dwelled in inadequate literature searches and absence of validity assessment of studies.Conclusion Meta-analysis could gather different findings from the same kind of nursing research.At present,the application of meta-analysis in many nursing areas is still blank in China.Nursing staff could make use of this analytical method to improve the level of nurse research.

  8. The Use of Dexamethasone in Support of High-Altitude Ground Operations: Review of the Literature & Current Training of U.S. Special Operations Medical Members

    Science.gov (United States)

    2013-03-14

    8) 8 mg twice daily starting the day before the ascent to 4,559 m throughout the 2-day study Dexamethasone improved VO2 - max (pɘ.05) and...4,559 m Dexamethasone improved VO2 - max (p=0.025); no significant difference existed in arterial O2 saturation during maximal exercise...AFRL-SA-WP-SR-2013-0006 The Use of Dexamethasone in Support of High-Altitude Ground Operations: Review of the Literature & Current

  9. Data mining for scientific publications

    Directory of Open Access Journals (Sweden)

    Mihai VLASE

    2006-12-01

    Full Text Available Searching scientific literature on the Web is a difficult task because of the large volume and the complex dynamics of the scientific literature and because of the complexity and narrow target of typical queries. The problem is compounded by differences among publication standards and formats used in various fields of knowledge. In this paper we review several specific solutions that apply or adapt data mining techniques to searching scientific publications.

  10. The physical and physiological effects of vacuum massage on the different skin layers: a current status of the literature.

    Science.gov (United States)

    Moortgat, Peter; Anthonissen, Mieke; Meirte, Jill; Van Daele, Ulrike; Maertens, Koen

    2016-01-01

    Vacuum massage is a non-invasive mechanical massage technique performed with a mechanical device that lifts the skin by means of suction, creates a skin fold and mobilises that skin fold. In the late 1970s, this therapy was introduced to treat traumatic or burn scars. Although vacuum massage was invented to treat burns and scars, one can find very little literature on the effects of this intervention. Therefore, the aim of this review is to present an overview of the available literature on the physical and physiological effects of vacuum massage on epidermal and dermal skin structures in order to find the underlying working mechanisms that could benefit the healing of burns and scars. The discussion contains translational analysis of the results and provides recommendations for future research on the topic. An extended search for publications was performed using PubMed, Web of Science and Google Scholar. Two authors independently identified and checked each study against the inclusion criteria. Nineteen articles were included in the qualitative synthesis. The two most reported physical effects of vacuum massage were improvement of the tissue hardness and the elasticity of the skin. Besides physical effects, a variety of physiological effects are reported in literature, for example, an increased number of fibroblasts and collagen fibres accompanied by an alteration of fibroblast phenotype and collagen orientation. Little information was found on the decrease of pain and itch due to vacuum massage. Although vacuum massage initially had been developed for the treatment of burn scars, this literature review found little evidence for the efficacy of this treatment. Variations in duration, amplitude or frequency of the treatment have a substantial influence on collagen restructuring and reorientation, thus implying possible beneficial influences on the healing potential by mechanotransduction pathways. Vacuum massage may release the mechanical tension associated with

  11. Current and future prospects for heat recovery from waste in European district heating systems: A literature and data review

    DEFF Research Database (Denmark)

    Persson, Urban; Münster, Marie

    2016-01-01

    Municipal solid waste has seen increasing annual volumes for many decades in contemporary Europe and constitutes, if not properly managed, an environmental problem due to local pollution and greenhouse gas emissions. From an energy perspective, waste is also an alternative fuel for power and heat...... heat distribution infrastructures, without which no large-scale recovery and utilisation of excess heat is possible. In this paper, which aims to estimate municipal solid waste volumes available for heat recovery in European district heating systems in 2030, a literature and data review is performed...

  12. Scientific publication

    Directory of Open Access Journals (Sweden)

    Getulio Teixeira Batista

    2007-06-01

    Full Text Available The necessary work for developing a scientific publication is sometimes underestimated and requires the effective participation of many players to obtain a result in good standard. Initially it depends upon the determination of the authors that decide to write the scientific article. Scientific writing is a very challenging and time consuming task, but at the same time essential for any scientist. A published scientific article is unquestionably one of the main indicators of scientific production, especially if published in a qualified scientific journal with highly qualified editorial committee and strict peer review procedure. By looking at evaluation criteria for scientific production of the several Thematic Scientific Committees of the Brazilian Council for Scientific and Technological Development (CNPq it becomes clear publications in scientific journals that has certified quality is the most important item in the evaluation of a scientist production.

  13. Current Situations of Competitive Scientific Research Projects for Agri-scientific Research Institutions: A Case Study of Tropical Crops Genetic Resources Institute of Chinese Academy of Tropical Agricultural Sciences

    Institute of Scientific and Technical Information of China (English)

    Haiyan; LUO; Qingqun; YAO; Lizhen; CHEN; Yu; ZHENG

    2015-01-01

    This paper collected and arranged competitive scientific research projects undertaken by Tropical Crops Genetic Resources Institute of Chinese Academy of Tropical Agricultural Sciences in 2003-2014. Through statistical analysis on quantity of projects,funded amount,age of person responsible,professional title of person responsible,academic degree of person responsible,research object,it discussed relevant characteristics and rules. Finally,it came up with pertinent measures and recommendations,in the hope of providing services for decision-making and scientific and technological management.

  14. [Spray for self-defense against subjects with aggressive behavior: review of the scientific literature on the use of oleoresin capsicum].

    Science.gov (United States)

    Clerici, Carlo Alfredo; Pelettii, Gianfranco; Veneroni, Laura; de Micheli, Angelo

    2012-01-01

    ABSTRACT. In several countries oleoresin capsicum (OC) spray is being used as non lethal weapon in recent years. In 2009 in Italy a Security Act has established that self-defence spray devices can lawfully be purchased and possessed by citizens; at the same time corps of local police started to adopt these devices for self defence and aid in arresting aggressive individuals. This article analizes the multidisciplinar literature about the efficacy and possible acute and long-term health risks of pepper spray for exposed individuals and police or civilians users. The paper also reports updated considerations about correct use of this devices.

  15. Unraveling Scientific Impact

    OpenAIRE

    Stremersch, S.; Camacho, N.M.A.; Vanneste, S.; Verniers, I.W.J.

    2014-01-01

    The number of citations a paper receives is the most commonly used measure of scientific impact. In this paper, we study not only the number but also the type of citations that 659 marketing articles generated. We discern five citation types: application, affirmation, negation, review and perfunctory mention (i.e., citing an article only indirectly without really using it). Prior literature in scientometrics recognizes that the former three types, on average, signal a higher level of scientif...

  16. Cancer survivorship research: a review of the literature and summary of current NCI-designated cancer center projects.

    Science.gov (United States)

    Harrop, J Phil; Dean, Julie A; Paskett, Electra D

    2011-10-01

    The number of cancer survivors and the amount of cancer survivorship research have grown substantially during the past three decades. This article provides a review of interventional and observational cancer survivorship research efforts as well as a summary of current cancer survivorship research projects being conducted by National Cancer Institute-designated cancer centers in an effort to identify areas that need further attention.

  17. What current literature tells us about sustainable diets: emerging research linking dietary patterns, environmental sustainability, and economics.

    Science.gov (United States)

    Auestad, Nancy; Fulgoni, Victor L

    2015-01-01

    The concept of sustainable diets, although not new, is gaining increased attention across the globe, especially in relation to projected population growth and growing concerns about climate change. As defined by the FAO (Proceedings of the International Scientific Symposium, Biodiversity and Sustainable Diets 2010; FAO 2012), "Sustainable diets are those diets with low environmental impacts which contribute to food and nutrition security and to healthy life for present and future generations." Consistent and credible science that brings together agriculture, food systems, nutrition, public health, environment, economics, culture, and trade is needed to identify synergies and trade-offs and to inform guidance on vital elements of healthy, sustainable diets. The aim of this article is to review the emerging research on environmental and related economic impacts of dietary patterns, including habitual eating patterns, nutritionally balanced diets, and a variety of different dietary scenarios. Approaches to research designs, methodologies, and data sources are compared and contrasted to identify research gaps and future research needs. To date, it is difficult to assimilate all of the disparate approaches, and more concerted efforts for multidisciplinary studies are needed.

  18. Open access: the changing face of scientific publishing.

    Science.gov (United States)

    Chatterjee, Pranab; Biswas, Tamoghna; Mishra, Vishala

    2013-04-01

    The debate on open access to scientific literature that has been raging in scholarly circles for quite some time now has been fueled further by the recent developments in the realm of the open access movement. This article is a short commentary on the current scenario, challenges, and the future of the open access movement.

  19. The factors of realization and differentiation of the scientific potential of young scientists

    Directory of Open Access Journals (Sweden)

    KATYA SHELESTUN

    2013-12-01

    Full Text Available In domestic and foreign scientists’ research the scientific potential is investigated through a series of economic indicators, but social and cultural aspects are not revealed. Scientists’ interest focuses primarily on the resource component of the scientific potential expressed through quantitative indexes (funding of science, number of academic staff involved in economics, the volume of scientific & technical work, etc.. The analyses of the current scientific literature have found that the concept of scientific potential with respect to young scientists has not been sufficiently studied.

  20. Reply to "Critical assessment of the current state of scientific knowledge, terminology, and research needs concerning the ecological effects of elevated atmospheric nitrogen deposition in China"

    Science.gov (United States)

    Gu, Fengxue; Zhang, Yuandong; Huang, Mei; Tao, Bo; Yan, Huimin; Guo, Rui; Li, Jie

    2017-03-01

    In their assessment, Pan et al. (2016) criticize that our estimation of 2.32 g N m-2 yr-1 in 2010 underestimates the total nitrogen (N) deposition amounts by a factor around two by comparing with the estimation of Xu et al. (2015). Our paper entitled "Nitrogen deposition and its effect on carbon storage in Chinese forests during 1981-2010" aims to evaluate the influence of elevated N deposition in China on carbon storage in forest ecosystems by using a process-based model. As limited by observed N deposition dataset availability, we developed a simple algorithm to evaluate the temporal and spatial variations in N deposition based on the relationships among N deposition, precipitation, N fertilizer use, and fuel consumption with reference to the method of Lin et al. (2000). Our results show that the rate of N deposition increased by 0.058 g N m-2 yr-1 between 1981 and 2010. The N deposition rate in 2010 was 2.32 g N m-2 yr-1, and it showed a large spatial variation from 0 to 0.25 g N m-2 yr-1 on the northwestern Qinghai-Tibet Plateau to over 4.5 g N m-2 yr-1 in the southeastern China. We really underestimated the total N deposition in China because we were lack of dry deposition observation dataset in our research. However, we think Pan et al. (2016) overestimated the difference between our estimation and that in Xu et al. (2015). It should be encouraged to discuss the past and current status of N deposition in China based on both observation and simulation. All comments, assessments and suggestions contribute to promote the scientific understanding of N deposition and its influence on ecosystems.

  1. Current Scientific Impact of Ss Cyril and Methodius University of Skopje, Republic of Macedonia in the Scopus Database (1960-2014).

    Science.gov (United States)

    Spiroski, Mirko

    2015-03-15

    The aim of this study was to analyze current scientific impact of Ss Cyril and Methodius University of Skopje, Republic of Macedonia in the Scopus Database (1960-2014). Affiliation search of the Scopus database was performed on November 23, 2014 in order to identify published papers from the Ss Cyril and Methodius University of Skopje (UC&M), Republic of Macedonia. A total number of 3960 articles (3055 articles from UC&M, 861 articles from Faculty of Medicine, UC&M, and 144 articles from Faculty of Pharmacy, UC&M) were selected for analysis (1960-2014). SCImago Journal Rank (SJR), Source Normalized Impact per Paper (SNIP) and h-index were calculated from the Scopus database. The number of published papers was sharply increased with maximum of 379 papers in 2012 year. The largest number of papers has been published in Macedonian Journal of Medical Sciences, Journal of Molecular Structure, Lecture Notes in Computer Science, Acta Pharmecutica, and Macedonian Journal of Chemistry and Chemical Engineering. The biggest SJR and SNIP has journal Nephrology Dialysis Transplantation. First three places of the top ten authors belong to Dimirovski GM, Gavrilovska L, and Gusev M. Top three places based on Scopus h-index (total number of published papers) belong to Kocarev L, Stafilov T, and Polenakovic M. The majority of papers originate from UC&M, but significant numbers of papers are affiliated to Faculty of Medicine, Faculty of Pharmacy, and Institute of Chemistry as members of UC&M, as well as Macedonian Academy of Sciences and Arts. Articles are the most dominant type of documents followed by conference papers, and review articles. Medicine is the most represented subject. Officials of the Ss Cyril and Methodius University of Skopje should undertake more effective and proactive policies for journal publishers and their Editorial Boards in order to include more journals from UC&M in the Scopus database.

  2. Current Scientific Impact of Ss Cyril and Methodius University of Skopje, Republic of Macedonia in the Scopus Database (1960-2014

    Directory of Open Access Journals (Sweden)

    Mirko Spiroski

    2015-01-01

    Full Text Available Aim: The aim of this study was to analyze current scientific impact of Ss Cyril and Methodius University of Skopje, Republic of Macedonia in the Scopus Database (1960-2014. Material and Methods: Affiliation search of the Scopus database was performed on November 23, 2014 in order to identify published papers from the Ss Cyril and Methodius University of Skopje (UC&M, Republic of Macedonia. A total number of 3960 articles (3055 articles from UC&M, 861 articles from Faculty of Medicine, UC&M, and 144 articles from Faculty of Pharmacy, UC&M were selected for analysis (1960-2014. SCImago Journal Rank (SJR, Source Normalized Impact per Paper (SNIP and h-index were calculated from the Scopus database. Results: The number of published papers was sharply increased with maximum of 379 papers in 2012 year. The largest number of papers has been published in Macedonian Journal of Medical Sciences, Journal of Molecular Structure, Lecture Notes in Computer Science, Acta Pharmecutica, and Macedonian Journal of Chemistry and Chemical Engineering. The biggest SJR and SNIP has journal Nephrology Dialysis Transplantation. First three places of the top ten authors belong to Dimirovski GM, Gavrilovska L, and Gusev M. Top three places based on Scopus h-index (total number of published papers belong to Kocarev L, Stafilov T, and Polenakovic M. The majority of papers originate from UC&M, but significant numbers of papers are affiliated to Faculty of Medicine, Faculty of Pharmacy, and Institute of Chemistry as a members of UC&M, as well as Macedonian Academy of Sciences and Arts. Articles are the most dominant type of documents followed by conference papers, and review articles. Medicine is the most represented subject. Conclusion: Officials of the Ss Cyril and Methodius University of Skopje should undertake more effective and proactive policies for journal publishers and their Editorial Boards in order to include more journals from UC&M in the Scopus database.

  3. Quantification of Global Left Ventricular Function: Comparison of Multidetector Computed Tomography and Magnetic Resonance Imaging. A Meta-analysis and Review of the Current Literature

    Energy Technology Data Exchange (ETDEWEB)

    Vleuten, P.A. van der; Willems, T.P.; Goette, M.J.; Tio, R.A.; Greuter, M.J.; Zijlstra, F.; Oudkerk, M. [Univ. Medical Centre Groningen (Netherlands). Depts. of Cardiology and Radiology

    2006-12-15

    Cardiac morbidity and mortality are closely related to cardiac volumes and global left ventricular (LV) function, expressed as left ventricular ejection fraction. Accurate assessment of these parameters is required for the prediction of prognosis in individual patients as well as in entire cohorts. The current standard of reference for left ventricular function is analysis by short-axis magnetic resonance imaging. In recent years, major extensive technological improvements have been achieved in computed tomography. The most marked development has been the introduction of the multidetector CT (MDCT), which has significantly improved temporal and spatial resolutions. In order to assess the current status of MDCT for analysis of LV function, the current available literature on this subject was reviewed. The data presented in this review indicate that the global left ventricular functional parameters measured by contemporary multi-detector row systems combined with adequate reconstruction algorithms and post-processing tools show a narrow diagnostic window and are interchangeable with those obtained by MRI.

  4. Prevalence of primary aldosteronism in patient's cohorts and in population-based studies--a review of the current literature.

    Science.gov (United States)

    Hannemann, A; Wallaschofski, H

    2012-03-01

    There is an ongoing controversy on the prevalence of primary aldosteronism (PA). We aimed to update a meta-analysis published in 2008, that compiled studies reporting the prevalence of positive ARR screening tests and PA. We therefore reviewed original studies published in 2008 or later to examine whether current reports provide similar, higher or lower prevalences of elevated ARRs or PA than reports included in the original meta-analysis. A systematic review of English articles using PubMed was conducted. Search and extraction of articles were performed by one review author; the second review author checked all extracted data. We identified 11 eligible studies. The updated, weighted mean prevalences of elevated ARRs and PA in primary care (prevalence of high ARRs 16.5%; prevalence of PA 4.3%) and referred patients (prevalence of high ARRs 19.6%; prevalence of PA 9.5%) were only marginally different from the mean values obtained in the original meta-analysis. Among the current studies the maximum values for the prevalence of elevated ARRs and PA were substantially lower than among the older studies. Our results confirm the main conclusions from the original meta-analysis. The prevalence of PA increases with the severity of hypertension and the inclusion of current study results did not alter the mean prevalences of elevated ARRs and PA in primary care and referred patients. Additionally, we found that current studies focus increasingly on patients in referral centers or special subgroups, while the prevalence of PA in the general hypertensive population is yet unknown.

  5. Randomized placebo-controlled trials of omega-3 polyunsaturated fatty acids in psychiatric disorders: a review of the current literature.

    Science.gov (United States)

    Politi, Pierluigi; Rocchetti, Matteo; Emanuele, Enzo; Rondanelli, Mariangela; Barale, Francesco

    2013-09-01

    A growing body of evidence suggests that omega (ω)-3 polyunsaturated fatty acids (PUFAs) are clinically useful in patients with psychiatric disorders. In the present review, we summarize the findings of randomized, placebo-controlled clinical trials that have focused on the potential therapeutic utility of ω-3 PUFAs in patients with mental illnesses. We searched the PubMed database for placebo-controlled clinical trials using the keywords "PUFAs", "omega-3", "eicosapentaenoic acid", and "docosahexaenoic acid" in combination with the following terms: "anxiety disorders", "mood disorders", "autism", "attention-deficit hyperactivity disorder" (ADHD), "personality disorders", and "schizophrenia". The literature review indicated that personality disorders, autism, and anxiety disorders have been investigated less frequently than mood disorders, schizophrenia, and ADHD. Although no definite conclusions can be drawn on the therapeutic efficacy of ω-3 PUFAs in the majority of the psychiatric illnesses examined here, the evidence suggests that these molecules have a potential preventive role in people at extremely high risk for developing psychosis. Future studies in the field should examine ω-PUFAs turnover in neural membranes. Moreover, special attention should be paid to potential confounds, such as smoking and dietary habits.

  6. Role of Motorcycle Running Lights in Reducing Motorcycle Crashes during Daytime; A Review of the Current Literature

    Directory of Open Access Journals (Sweden)

    Seyed Rasoul Davoodi

    2015-07-01

    Full Text Available In comparison to other transportation modes, riding motorcycle is prone to accidents. Motorcyclists are more exposed to physical injury than the car drivers. Many multi-vehicle motorcycles crashes occur, there is right-of- way violation takes place in which another vehicle turns in fronts of a motorcycle, or a sudden cross of path of an on-coming motorcycle. One main factor which leads to high rate of motorcycle crashes is lack of conspicuity of motorcycles by other road users especially during day time traffic. This paper highlights previous studies on the implementation of motorcycle DRLs, focusing on the efficacy of the DRLs to improve motorcycle conspicuity. This paper reviews the impacts of DRL by motorcyclists on multi-vehicle motorcycle crash. The three categories of effects of motorcycle DRLs were reviewed. All literature, supporting that operating headlights during daytime appears to be an influential and effective approach to reduce rate of collision by improving motorcycle’s conspicuity in traffic. The motorcycle DRLs managed to reduce about 4 to 20% of motorcycle crash risk. This paper also recommends that motorcycle DRLs must be used globally, especially in countries with high motorcycle accidents to improve the safety of the riders as well as their pillion riders.

  7. Female Genital Mutilation: A Literature Review of the Current Status of Legislation and Policies in 27 African Countries and Yemen.

    Science.gov (United States)

    Muthumbi, Jane; Svanemyr, Joar; Scolaro, Elisa; Temmerman, Marleen; Say, Lale

    2015-09-01

    This article discusses the results of a literature review that has assessed the impact of Female Genital Mutilation (FGM) legislation in 28 countries (27 in Africa and Yemen) where FGM is concentrated. Evidence on the impact of FGM legislation was available on prevalence of FGM; changes in societal attitudes and perceptions of FGM; knowledge and awareness of FGM legislation and consequences, and the impact on medicalization. While the majority of countries have adopted legal frameworks prohibiting FGM, these measures have been ineffective in preventing and/or in accelerating the abandonment of the practice. Anti-FGM laws have had an impact on prevalence in only two countries where strict enforcement of legal measures has been complemented by robust monitoring, coupled with robust advocacy efforts in communities. Owing to poor enforcement and lax penalties, legal measures have had a limited impact on medicalization. Similarly, legal frameworks have had a limited impact on societal attitudes and perceptions of FGM, with evidence suggesting rigid enforcement of FGM laws has in some instances been counterproductive. Although evidence suggests legislation has not influenced the decline in FGM in the majority of countries, legal frameworks are nevertheless key components of a comprehensive response to the elimination and abandonment of the practice, and need to be complemented by measures that address the underlying socio-cultural norms that are the root of this practice.

  8. Towards a conceptual framework demonstrating the effectiveness of audiovisual patient descriptions (patient video cases: a review of the current literature

    Directory of Open Access Journals (Sweden)

    Roland Damian

    2012-12-01

    Full Text Available Abstract Background Technological advances have enabled the widespread use of video cases via web-streaming and online download as an educational medium. The use of real subjects to demonstrate acute pathology should aid the education of health care professionals. However, the methodology by which this effect may be tested is not clear. Methods We undertook a literature review of major databases, found relevant articles relevant to using patient video cases as educational interventions, extracted the methodologies used and assessed these methods for internal and construct validity. Results A review of 2532 abstracts revealed 23 studies meeting the inclusion criteria and a final review of 18 of relevance. Medical students were the most commonly studied group (10 articles with a spread of learner satisfaction, knowledge and behaviour tested. Only two of the studies fulfilled defined criteria on achieving internal and construct validity. The heterogeneity of articles meant it was not possible to perform any meta-analysis. Conclusions Previous studies have not well classified which facet of training or educational outcome the study is aiming to explore and had poor internal and construct validity. Future research should aim to validate a particular outcome measure, preferably by reproducing previous work rather than adopting new methods. In particular cognitive processing enhancement, demonstrated in a number of the medical student studies, should be tested at a postgraduate level.

  9. Non-hematopoietic essential functions of bone marrow cells: a review of scientific and clinical literature and rationale for treating bone defects

    Directory of Open Access Journals (Sweden)

    David B. Harrell

    2015-12-01

    Full Text Available Hematopoiesis as the only essential function of bone marrow cells has been challenged for several decades through basic science (in vitro and in vivo and clinical data. Such work has shed light on two other essential functions of bone marrow cells: osteopoiesis and angiogenesis/vasculogenesis. Clinical utility of autologous concentrated bone marrow aspirate (CBMA has demonstrated both safety and efficacy in treating bone defects. Moreover, CBMA has been shown to be comparable to the gold standard of iliac crest bone graft (ICBG, or autograft, with regard to being osteogenic and osteoinductive. ICBG is not considered an advanced therapy medicinal product (ATMP, but CBMA may become regulated as an ATMP. The European Medicines Agency Committee for Advanced Therapies (EMA:CAT has issued a reflection paper (20 June 2014 in which reversal of the 2013 ruling that CBMA is a non-ATMP has been proposed. We review bone marrow cell involvement in osteopoiesis and angiogenesis/vasculogenesis to examine EMA:CAT 2013 decision to use CBMA for treatment of osteonecrosis (e.g, of the femoral head should be considered a non-ATMP. This paper is intended to provide discussion on the 20 June 2014 reflection paper by reviewing two non-hematopoietic essential functions of bone marrow cells. Additionally, we provide clinical and scientific rationale for treating osteonecrosis with CBMA.

  10. The effectiveness of current approaches to workplace stress management in the nursing profession: an evidence based literature review

    Science.gov (United States)

    Mimura, C; Griffiths, P

    2003-01-01

    The effectiveness of current approaches to workplace stress management for nurses was assessed through a systematic review. Seven randomised controlled trials and three prospective cohort studies assessing the effectiveness of a stress management programmes were identified and reviewed. The quality of research identified was weak. There is more evidence for the effectiveness of programmes based on providing personal support than environmental management to reduce stressors. However, since the number and quality of studies is low, the question as to which, if any, approach is more effective cannot be answered definitively. Further research is required before clear recommendations for the use of particular interventions for nursing work related stress can be made. PMID:12499451

  11. Current Methods in Health Behavior Research Among U.S. Community College Students: A Review of the Literature.

    Science.gov (United States)

    Pokhrel, Pallav; Little, Melissa A; Herzog, Thaddeus A

    2014-06-01

    The majority of health behavior research involving college students in the United States has focused on 4-year college students. Two-year or community college students have been less studied, although a significant proportion of U.S. undergraduates, primarily those from disadvantaged socioeconomic and/or racial/ethnic background, are enrolled in community colleges. Thus, there is a need to enhance health behavior and health promotion research among community college students. This study systematically reviewed 42 published, peer-reviewed health behavior studies conducted among U.S. community college students in order to determine the current state of research in the area with regard to behaviors studied, research designs used, recruitment and data collection strategies practiced, rates of student participation, and characteristics of the participants represented. Findings identified the methodological limitations of current research and suggested optimal recruitment and data collection methods suitable for various research needs. Findings are discussed in the context of enhancing health behavior research among U.S. community college students.

  12. Scientific literature on monosialoganglioside in the Science Citation Index-Expanded: A bibliometric analysis of articles from 1942 to 2011 by each decade.

    Science.gov (United States)

    Xu, Yanli; Li, Miaojing; Liu, Zhijun; Liu, Ruichun; Zhang, Jianzhong

    2012-01-05

    The monosialoganglioside (GM1) is a popular topic of research but the bibliometric analysis of GM1 over the decades in Science Citation Index-Expanded (SCI-E) remains poorly understood. To identify the global research and to improve the understanding of research trends in the GM1 field from 1942 to 2011. A bibliometric study. We performed a bibliometric analysis based on the SCI-E published by the Institute of Scientific Information. Articles closely related to GM1 were included. Exclusive criteria: (1) Articles related to gangliosidosis, disialo-ganglioside, trisialo-ganglioside or ganglioside GQIb. (2) Document types such as meeting abstracts, reviews, proceedings papers, notes, and letters. (1) Type of publication output; (2) number of author outputs; (3) distribution of output in subject categories; (4) publication distribution of countries; (5) distribution of output in journals, and (6) distribution of citations in each decade. During 1942 to 2011, there were 10 126 papers on GM1 that were added to the SCI. Articles (8 004) were the most frequently used document type comprising 79.0%, followed by meeting abstracts, reviews and proceedings papers. Research on GM1 could be found in the SCI from 1942, it was developed in the 1970s, greatly increased in the 1980s, and reached a peak in the 1990s, and it was slightly decreased in 2000. The distribution of subject categories showed that GM1 research covered both clinical and basic science research. The USA, Japan, and Germany were the three most productive countries, and the publication numbers in the USA were highest in all decades. The Journal of Biological Chemistry, Journal of Neurochemistry and Biochemistry were core subject journals in GM1 studies in each decade. This study highlights the topics in GM1 research that are being published around the world.

  13. Scientific literature on monosialoganglioside in the Science Citation Index-Expanded bibliometric analysis of articles from 1942 to 2011 by each decade

    Institute of Scientific and Technical Information of China (English)

    Yanli Xu; Miaojing Li; Zhijun Liu; Ruichun Liu; Jianzhong Zhang

    2012-01-01

    BACKGROUND: The monosialoganglioside (GM1) is a popular topic of research but the bibliometric analysis of GM1 over the decades in Science Citation Index-Expanded (SCI-E) remains poorly understood.OBJECTIVE: To identify the global research and to improve the understanding of research trends in the GM1 field from 1942 to 2011. DESIGN: A bibliometric study. DATA RETRIEVAL: We performed a bibliometric analysis based on the SCI-E published by the Institute of Scientific Information. INCLUSIVE CRITERIA: Articles closely related to GM1 were included. Exclusive criteria: (1) Articles related to gangliosidosis, disialo-ganglioside, trisialo-ganglioside or ganglioside GQIb. (2) Document types such as meeting abstracts, reviews, proceedings papers, notes, and letters. MAIN OUTCOME MEASURES: (1) Type of publication output; (2) number of author outputs; (3) distribution of output in subject categories; (4) publication distribution of countries; (5) distribution of output in journals, and (6) distribution of citations in each decade.RESULTS: During 1942 to 2011, there were 10 126 papers on GM1 that were added to the SCI. Articles (8 004) were the most frequently used document type comprising 79.0%, followed by meeting abstracts, reviews and proceedings papers. Research on GM1 could be found in the SCI from 1942, it was developed in the 1970s, greatly increased in the 1980s, and reached a peak in the 1990s, and it was slightly decreased in 2000. The distribution of subject categories showed that GM1 research covered both clinical and basic science research. The USA, Japan, and Germany were the three most productive countries, and the publication numbers in the USA were highest in all decades. The Journal of Biological Chemistry, Journal of Neurochemistry and Biochemistry were core subject journals in GM1 studies in each decade. CONCLUSION: This study highlights the topics in GM1 research that are being published around the world.

  14. How the risk of liver cancer changes after alcohol cessation: A review and meta-analysis of the current literature

    Directory of Open Access Journals (Sweden)

    Heckley Gawain A

    2011-10-01

    Full Text Available Abstract Background It is well established that drinking alcohol raises the risk of liver cancer (hepatocellular carcinoma. However, it has not been sufficiently established as to whether or not drinking cessation subsequently reduces the risk of liver cancer and if it does reduce the risk how long it takes for this heightened risk to fall to that of never drinkers. This question is important for effective policy design and evaluation, to establish causality and for motivational treatments. Methods A systematic review and meta-analysis using the current available evidence and a specific form of Generalised Least Squares is performed to assess how the risk of liver cancer changes with time for former drinkers. Results Four studies are found to have quantified the effect of drinking cessation on the risk of liver cancer. The meta-analysis suggests that the risk of liver cancer does indeed fall after cessation by 6-7% a year, but there remains a large uncertainty around this estimate both statistically and in its interpretation. As an illustration it is estimated that a time period of 23 years is required after drinking cessation, with a correspondingly large 95% confidence interval of 14 to 70 years, for the risk of liver cancer to be equal to that of never drinkers. Conclusion This is a relatively under researched area and this is reflected in the uncertainty of the findings. It is our view that it is not possible to extrapolate the results found here to the general population. Too few studies have addressed this question and of the studies that have, all have significant limitations. The key issue amongst the relevant studies is that it appears that current drinkers, abstainers and former drinkers are not composed of, or effectively adjusted to be, similar populations making inferences about risk changes impossible. This is a very difficult area to study effectively, but it is an important topic. More work is required to reduce both statistical

  15. Currently Available Tools and Teaching Strategies for the Interprofessional Education of Students in Health Professions: Literature review.

    Science.gov (United States)

    Khan, Nelofar S; Shahnaz, Syed I; Gomathi, Kadayam G

    2016-08-01

    Interprofessional education (IPE) is designed to provide students from different health sectors with opportunities to work together to enhance future collaboration. The implementation of IPE activities is a current trend in various countries. This review exclusively targets IPE issues involving undergraduate health profession students and highlights various approaches in different regions. A total of 28 articles published in peer-reviewed journals between January 2012 and July 2015 were assessed to determine recent trends in IPE implementation. Nine main strategies were identified: simulation-based education programmes; rotations in rural and community settings; interprofessional training wards; patient-centred case studies; theme-centred workshops; student seminars; student-delivered lectures; health promotion activities; and interactive lectures in a common setting. Many of these institutions had not restricted themselves to a single strategy and supplemented these activities with additional teaching or learning methods. Recommendations gathered from these diverse approaches may assist the development of sustainable strategies for implementing IPE in undergraduate medical curricula.

  16. The influence of cultural capital on consumption of scientific culture: A survey of visitors to an open house event at a public scientific research institution.

    Science.gov (United States)

    Kato-Nitta, Naoko

    2013-04-01

    Based on the concept of cultural capital, this study explores the relationship between habitual behaviors of individuals regarding their past accumulation of such capital and current responses to a scientific institute's public outreach activity. At an open house held at the Institute for Molecular Science (IMS), anonymous questionnaires were distributed among 1,350 visitors and collected from 785 of them (collection rate = 58.1%). The results, measuring the past five to six years, showed that the respondents accumulated cultural capital through participation in scientific activities as well as in activities involving art, music, and literature. Given these quantified values, correlations between citizens' levels of accumulated cultural capital and their current scientific consumption behavior were studied. A statistical analysis of the two components of cultural capital (science and technology/art and literature) showed that people's accumulated scientific capital influenced their current behavior and revealed a correlation between the two components.

  17. Scientific publications in public, environmental and occupational health journals by authors from China, Japan and Korea in East Asia: A 10-year literature survey from 2003 to 2012.

    Science.gov (United States)

    Li, Meina; Liu, Xiaodong; Zhang, Lulu

    2015-01-01

    To compare the number and quality of public, environmental and occupational health articles published in international journals from the 3 major non-English speaking countries of East Asia: China, Japan and Korea. Public, environmental and occupational health articles from China, Japan and Korea that were published in 161 journals from 2003 to 2012 were retrieved from the Science Citation Index Expanded (SCIE) database. We recorded the numbers of total articles, impact factors (IF), citations, number of articles in top 10 journals, references as well as the article distribution from various regions in China. From 2003 to 2012, China, Japan and Korea published 5713, 3802 and 1967 papers respectively, with accumulated impact factor of 14 934.55, 8758.36 and 6189.25, the average impact factor of 2.61, 2.30 and 3.15 and the average citation numbers per document of 5.08, 6.49 and 5.25. In the top 10 high-impact public, environmental and occupational health journals, China, Japan and Korea accounted for 50.19%, 20.34% and 29.47% of all the papers published in those journals, respectively. Total impact factors of the most popular 10 papers for China, Japan and Korea were: 26.23, 27.08 and 26.91. Distribution of scientific papers among regions was unbalanced in China, for Hong Kong and Taiwan it accounted for 47.31% of the papers from China. From 2003 to 2012, both the quality and number of papers from China published in public, environmental and occupational health journals have greatly improved. China exceeded Japan and Korea in the number, accumulated impact factor, total citation times and the average number of references, while Korea had the highest average impact factor. Japan had the highest journal impact factor among the most popular journals, and the highest average citation number per document. This work is available in Open Access model and licensed under a CC BY-NC 3.0 PL license.

  18. Health outcomes of children born after IVF/ICSI: a review of current expert opinion and literature.

    Science.gov (United States)

    Fauser, B C J M; Devroey, P; Diedrich, K; Balaban, B; Bonduelle, M; Delemarre-van de Waal, H A; Estella, C; Ezcurra, D; Geraedts, J P M; Howles, C M; Lerner-Geva, L; Serna, J; Wells, D

    2014-02-01

    The Sixth Evian Annual Reproduction (EVAR) Workshop Group Meeting was held to evaluate the impact of IVF/intracytoplasmic sperm injection on the health of assisted-conception children. Epidemiologists, reproductive endocrinologists, embryologists and geneticists presented data from published literature and ongoing research on the incidence of genetic and epigenetic abnormalities and congenital malformations in assisted-conception versus naturally conceived children to reach a consensus on the reasons for potential differences in outcomes between these two groups. IVF-conceived children have lower birthweights and higher peripheral fat, blood pressure and fasting glucose concentrations than controls. Growth, development and cognitive function in assisted-conception children are similar to controls. The absolute risk of imprinting disorders after assisted reproduction is less than 1%. A direct link between assisted reproduction and health-related outcomes in assisted-conception children could not be established. Women undergoing assisted reproduction are often older, increasing the chances of obtaining abnormal gametes that may cause deviations in outcomes between assisted-conception and naturally conceived children. However, after taking into account these factors, it is not clear to what extent poorer outcomes are due to the assisted reproduction procedures themselves. Large-scale, multicentre, prospective epidemiological studies are needed to investigate this further and to confirm long-term health consequences in assisted-conception children. Assisted reproduction treatment is a general term used to describe methods of achieving pregnancy by artificial means and includes IVF and sperm implantation. The effect of assisted reproduction treatment on the health of children born using these artificial methods is not fully understood. In April 2011, fertility research experts met to give presentations based on research in this area and to look carefully at the evidence

  19. Yttrium-90 selective internal radiation therapy with glass microspheres for hepatocellular carcinoma: Current and updated literature review

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Edward Wolfgang; Alanic, Lourdes [Div. of Interventional Radiology, Dept. of Radiology, UCLA Medical Center, David Geffen School of Medicine at UCLA, Los Angeles (United States); Cho, Sung Ki [Div. of Interventional Radiology, Dept. of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul (Korea, Republic of); Saab, Sammy [Div. of Hepatology, Dept. of Medicine, Pfleger Liver Institute, University of California at Los Angeles, Los Angeles (United States)

    2016-07-15

    Hepatocellular carcinoma is the most common primary liver cancer and it represents the majority of cancer-related deaths in the world. More than 70% of patients present at an advanced stage, beyond potentially curative options. Ytrrium-90 selective internal radiation therapy (Y90-SIRT) with glass microspheres is rapidly gaining acceptance as a potential therapy for intermediate and advanced stage primary hepatocellular carcinoma and liver metastases. The technique involves delivery of Y90 infused glass microspheres via the hepatic arterial blood flow to the appropriate tumor. The liver tumor receives a highly concentrated radiation dose while sparing the healthy liver parenchyma due to its preferential blood supply from portal venous blood. There are two commercially available devices: TheraSphere® and SIR-Spheres®. Although, Y90-SIRT with glass microspheres improves median survival in patients with intermediate and advanced hepatocellular carcinoma and has the potential to downstage hepatocellular carcinoma so that the selected candidates meet the transplantable criteria, it has not gained widespread acceptance due to the lack of large randomized controlled trials. Currently, there are various clinical trials investigating the use of Y90-SIRT with glass microspheres for treatment of hepatocellular carcinoma and the outcomes of these trials may result in the incorporation of Y90-SIRT with glass microspheres into the treatment guidelines as a standard therapy option for patients with intermediate and advanced stage hepatocellular carcinoma.

  20. Yttrium-90 Selective Internal Radiation Therapy with Glass Microspheres for Hepatocellular Carcinoma: Current and Updated Literature Review

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Edward Wolfgang; Alanis, Lourdes [Division of Interventional Radiology, Department of Radiology, UCLA Medical Center, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 (United States); Cho, Sung-Ki [Division of Interventional Radiology, Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351 (Korea, Republic of); Saab, Sammy [Division of Hepatology, Department of Medicine, Pfleger Liver Institute, University of California at Los Angeles, Los Angeles, CA 90024 (United States)

    2016-11-01

    Hepatocellular carcinoma is the most common primary liver cancer and it represents the majority of cancer-related deaths in the world. More than 70% of patients present at an advanced stage, beyond potentially curative options. Ytrrium-90 selective internal radiation therapy (Y90-SIRT) with glass microspheres is rapidly gaining acceptance as a potential therapy for intermediate and advanced stage primary hepatocellular carcinoma and liver metastases. The technique involves delivery of Y90 infused glass microspheres via the hepatic arterial blood flow to the appropriate tumor. The liver tumor receives a highly concentrated radiation dose while sparing the healthy liver parenchyma due to its preferential blood supply from portal venous blood. There are two commercially available devices: TheraSphere® and SIR-Spheres®. Although, Y90-SIRT with glass microspheres improves median survival in patients with intermediate and advanced hepatocellular carcinoma and has the potential to downstage hepatocellular carcinoma so that the selected candidates meet the transplantable criteria, it has not gained widespread acceptance due to the lack of large randomized controlled trials. Currently, there are various clinical trials investigating the use of Y90-SIRT with glass microspheres for treatment of hepatocellular carcinoma and the outcomes of these trials may result in the incorporation of Y90-SIRT with glass microspheres into the treatment guidelines as a standard therapy option for patients with intermediate and advanced stage hepatocellular carcinoma.

  1. Cell Transplantation and Neuroengineering Approach for Spinal Cord Injury Treatment: A Summary of Current Laboratory Findings and Review of Literature.

    Science.gov (United States)

    Lin, Xin-Yi; Lai, Bi-Qin; Zeng, Xiang; Che, Ming-Tian; Ling, Eng-Ang; Wu, Wutian; Zeng, Yuan-Shan

    2016-01-01

    Spinal cord injury (SCI) can cause severe traumatic injury to the central nervous system (CNS). Current therapeutic effects achieved for SCI in clinical medicine show that there is still a long way to go to reach the desired goal of full or significant functional recovery. In basic medical research, however, cell transplantation, gene therapy, application of cytokines, and biomaterial scaffolds have been widely used and investigated as treatments for SCI. All of these strategies when used separately would help rebuild, to some extent, the neural circuits in the lesion area of the spinal cord. In light of this, it is generally accepted that a combined treatment may be a more effective strategy. This review focuses primarily on our recent series of work on transplantation of Schwann cells and adult stem cells, and transplantation of stem cell-derived neural network scaffolds with functional synapses. Arising from this, an artificial neural network (an exogenous neuronal relay) has been designed and fabricated by us-a biomaterial scaffold implanted with Schwann cells modified by the neurotrophin-3 (NT-3) gene and adult stem cells modified with the TrkC (receptor of NT-3) gene. More importantly, experimental evidence suggests that the novel artificial network can integrate with the host tissue and serve as an exogenous neuronal relay for signal transfer and functional improvement of SCI.

  2. Currently Available Tools and Teaching Strategies for the Interprofessional Education of Students in Health Professions; Literature review

    Directory of Open Access Journals (Sweden)

    Syed I. Shahnaz

    2016-08-01

    Full Text Available Interprofessional education (IPE is designed to provide students from different health sectors with opportunities to work together to enhance future collaboration. The implementation of IPE activities is a current trend in various countries. This review exclusively targets IPE issues involving undergraduate health profession students and highlights various approaches in different regions. A total of 28 articles published in peer-reviewed journals between January 2012 and July 2015 were assessed to determine recent trends in IPE implementation. Nine main strategies were identified: simulation-based education programmes; rotations in rural and community settings; interprofessional training wards; patient-centred case studies; theme-centred workshops; student seminars; student-delivered lectures; health promotion activities; and interactive lectures in a common setting. Many of these institutions had not restricted themselves to a single strategy and supplemented these activities with additional teaching or learning methods. Recommendations gathered from these diverse approaches may assist the development of sustainable strategies for implementing IPE in undergraduate medical curricula.

  3. Los costos de la enfermedad laboral: revisión de literatura / Cost of occupational diseases: a review of scientific literature

    Directory of Open Access Journals (Sweden)

    Martha I. Riaño-Casallas

    2015-09-01

    Full Text Available Resumen Objetivo: identificar el estado de desarrollo de la investigación sobre los costos de la enfermedad laboral que ha sido publicada en la literatura durante la última década en el mundo. Metodología: se realizó una búsqueda sistemática de literatura, altamente sensible, con el objetivo de identificar publicaciones que se adaptaran a los criterios de inclusión predefinidos por los autores. Se consultaron bases de datos como Pubmed, Ebsco, Lilacs, Online Wiley, Embase y Springer. El periodo de tiempo consultado fue 2000-2013. Resultados: Se incluyeron 54 artículos, de los cuales el mayor porcentaje están escritos en inglés, la mayoría fue producto de investigaciones realizadas en Estados Unidos. La metodología utilizada principalmente por los autores de los artículos fue del tipo de estudios de carga y costos de la enfermedad. Los costos incluidos en estas publicaciones fueron directos e indirectos en su mayoría y la perspectiva predominante fue la de tipo social. Conclusiones: Las economías más avanzadas del mundo son las que en su mayoría realizan este tipo de investigaciones, balance que resalta la importancia de realizar estos estudios para economías de países en desarrollo. Con respecto al lenguaje de publicación solamente se encontraron publicaciones en español realizadas en España, de ahí que sea necesario adelantar más estudios de este tipo en Latinoamérica. / Abstract Objective: look the development of research about the work related illness published in the literature in different years, countries and economic activities and knows about the point of view to calculate the cost. Methodology: it was performance a systematic search, highly sensivity with the purpose of identify publications that could be accomplishment with inclusion criteria predefined by the authors. Databases such as PubMed, Ebsco, Lilacs, Online Wiley, Springer and Embase were consulted. The consultation period was from 2000 to 2013

  4. [Challenge in scientific publication].

    Science.gov (United States)

    Volpato, Gilson Luiz; de Freitas, Eliane Gonçalves

    2003-05-01

    We discuss the main problems which make a scientific text difficult to find, to be read or to be accepted by readers. A scientific text is considered a logical argument. Therefore, methods, results and data from literature are premises supporting the conclusions of the work; and in the "Introduction" session, the justification corroborates the objective of the study. This conception makes the text a hermetically coherent structure where only the necessary data should be included (some controversy is still pertinent). In a second step, we show formal mistakes in scientific writing which make texts less attractive. Thus, we give examples of errors or inadequacy of formal aspects of presenting titles, abstracts, results (figures and tables), and grammar mistakes in Portuguese (but also valid for English grammar). After that, we emphasize the need for writing in international language (English) and for publication in periodicals with international impact on the scientific community. Finally, considerations to improve the Brazilian periodicals in the biological area are presented.

  5. Taming theory with thought experiments: Understanding and scientific progress.

    Science.gov (United States)

    Stuart, Michael T

    2016-08-01

    I claim that one way thought experiments contribute to scientific progress is by increasing scientific understanding. Understanding does not have a currently accepted characterization in the philosophical literature, but I argue that we already have ways to test for it. For instance, current pedagogical practice often requires that students demonstrate being in either or both of the following two states: 1) Having grasped the meaning of some relevant theory, concept, law or model, 2) Being able to apply that theory, concept, law or model fruitfully to new instances. Three thought experiments are presented which have been important historically in helping us pass these tests, and two others that cause us to fail. Then I use this operationalization of understanding to clarify the relationships between scientific thought experiments, the understanding they produce, and the progress they enable. I conclude that while no specific instance of understanding (thus conceived) is necessary for scientific progress, understanding in general is.

  6. Social differences in traffic injury risks in childhood and youth--a literature review and a research agenda

    DEFF Research Database (Denmark)

    Laflamme, L; Diderichsen, Finn

    2000-01-01

    The paper reviews the scientific literature concerning social differences in traffic injuries in childhood in order to highlight the current state of knowledge and to draw the main lines of a research agenda.......The paper reviews the scientific literature concerning social differences in traffic injuries in childhood in order to highlight the current state of knowledge and to draw the main lines of a research agenda....

  7. Statistical Analysis on the Scientific Literature of Tea Economics%茶经济类科技文献的统计与分析

    Institute of Scientific and Technical Information of China (English)

    朱永兴; 姜爱芹

    2012-01-01

    1449 Chinese literatures with tea economic themes were collected and filtered. With these articles statistical analysis on bibliometrics and keywords analysis were carried out. Results showed that during the latest 10 years the number of tea economic articles developed as a path of increasing curve with a low valley; these articles were published on 461 journals, among which the top 3 journals published more than 50 articles in each; and also there are 64.2% journals only published 1 article in each. There are 1 152 first authors in these 1 449 articles, among which there are 12 first authors who published more than 5 articles in each. These first authors affiliate to 803 institutions, which mainly belong to high education field and agriculture field, and fewer belong to research and economic institutions. The keyword analysis results showed that there are totally 3 642 keywords in 1 449 tea economic articles with total frequency of 8 595. The keywords with highest frequencies as follows: "tea industry", "industrialization", "development", "countermeasure", "brand", "famous tea", "organic tea", "Pu-erh tea", "sustainable development", "economic effect", "trade", "market", etc. In different years there are different high frequency keywords. In recent years, it occurrences some new keywords, in which the most important ones are "dark tea", "market construction", "tea industry association", "distract brand", "brand marketing", "industrial structure", etc. In the latest 10 years, the conceptions of tea brand, tea culture were gotten more attentions. Whereas, the attention to the tea export concept was dropped down for several years, but recovered in some degree in recent 3 years.%搜集、整理了中文茶经济类科技文献1 449篇,从文献统计和关键词分析的角度对其进行综述.文献统计显示,该类文献的数量在最近10年中呈现出具一定下凹度的曲线向上的增长趋势;共有461种期刊刊登茶经济类文献,其中发表50

  8. New Thoughts about the Theoretical System of Current Comparative Literature%比较文学学科理论体系新思考

    Institute of Scientific and Technical Information of China (English)

    赵渭绒; 曹顺庆

    2012-01-01

    本文从三个方面对当前的比较文学学科理论体系进行新的思考。首先,指出学科发展第一、二阶段存在的理论缺陷及不足,指出影响研究既有实证性特点又有非实证性特点;平行研究认为不同文明之间不具备可比性,使其本身不具备"世界性胸怀"。其次,将差异性作为可比性提出来,学界不宜仅仅"求同"更应关注差异,笔者提出的比较文学变异学理论将进一步地完善比较文学学科理论体系。最后,指出比较文学的未来和发展趋势是进入世界文学发展阶段,在这一阶段中国学者将担任重要使命。%This article provides a new thought about the theoritical system of current comparative literature in three aspects. Firstly, it points out the drawbacks and weaknesses of the 1st and 2nd phases of the development of this discipline, namely the positivist and non-positivist characteristic of influence study, and the lack of a "world mind" in parallel study by claiming that there's no comparability between different cultures. Secondly, the cultural diversity should be highlighted as comparability since we should not only seek the common ground but also pay attention to the differences. The variation theory in eomparative literature raised by the present author can help complete the theoretical system of comparative literature. Thirdly, this artiele points out that eom- parative literature will enter the phase of world literature, in which Chinese scholars will play an important role.

  9. Scientific news

    NARCIS (Netherlands)

    NN,

    1994-01-01

    The Rijksherbarium/Hortus Botanicus acquired funds through NWO (Netherlands Organisation for Scientific Research) to participate in a 7-year interdisciplinary cooperative programme of Indonesian and Dutch scientific institutions aiming at research in Irian Jaya, Cenderawasih province (the Bird’s Hea

  10. Scientific Progress in Strategic Management

    DEFF Research Database (Denmark)

    Foss, Nicolai

    Does the RBV represent a case of scientific progress? And has it emerged as the dominant approach to the analysis of competitive advantage for this reason? Conventional criteria for scientific progress, notably those of the growth of knowledge literature, are not particularly helpful for understa...

  11. Haunted by the ghost in the machine. Commentary on "The spirituality of human consciousness: a Catholic evaluation of some current neuro-scientific interpretations".

    Science.gov (United States)

    Miller, James B

    2012-09-01

    Metaphysical and epistemological dualism informs much contemporary discussion of the relationships of science and religion, in particular in relation to the neurosciences and the religious understanding of the human person. This dualism is a foundational artifact of modern culture; however, contemporary scientific research and historical theological scholarship encourage a more holistic view wherein human personhood is most fittingly understood as an emergent phenomenon of, but not simply reducible to, evolutionary and developmental neurobiology.

  12. Use of {sup 99m}Tc 2-methoxyisobutyl isonitrile in minimally invasive radioguided surgery in patients with primary hyperparathyroidism: A narrative review of the current literature

    Energy Technology Data Exchange (ETDEWEB)

    Denmeade, Kristie A [Nuclear Medicine and Ultrasound Department, Bankstown-Lidcombe Hospital, Bankstown, New South Wales (Australia); Constable, Chris [Brain and Mind Research Institute, University of Sydney, New South Wales (Australia); Reed, Warren M [Discipline of Medical Radiation Sciences, Faculty of Health Sciences, The University of Sydney, New South Wales (Australia); Nuclear Medicine and Ultrasound Department, Bankstown-Lidcombe Hospital, Bankstown, New South Wales (Australia)

    2013-06-15

    The use of technetium-99m 2-methoxyisobutyl isonitrile ({sup 99m}Tc MIBI) for assistance in minimally invasive radioguided surgery (MIRS) is growing in popularity as a safe, effective, and proficient technique used for parathyroidectomy in primary hyperparathyroidism (PHPT) treatment. Previously, the preferred treatment for PHPT was bilateral neck exploration (BNE), a very invasive, costly, and lengthy procedure. However, as a large majority (80–85% of cases of PHPT) are attributed to a single parathyroid adenoma (PA), a simpler more direct technique such as MIRS is a far better option. The following article is an exploration of the current literature concerning varied protocols utilizing {sup 99m}Tc MIBI for assistance in MIRS for patients undergoing treatment of PHPT. This technique boasts many advantageous outcomes for patients suffering from PHPT. These include a reduction in cost, operating time, and patient recovery; less evidence of post-surgical hypocalcaemia, less pain, and complications; superior cosmetic results; same-day discharge; and the possibility of local anaesthesia which is particularly beneficial in elderly patients. Better outcomes for patients with deep or ectopic PAs, reduced intra-operative complications, and improved cosmetic outcomes for patients who have previously undergone thyroid and/or parathyroid surgery are also advantageous. Of the literature reviewed it was also found that no patients suffered any major surgical complications such as laryngeal nerve palsy or permanent hypoparathyroidism using {sup 99m}Tc MIBI for assistance in MIRS.

  13. HENOCH-SCHÖNLEIN PURPURA WITH AN ATYPICAL PRESENTATION OF THE DISEASE – presentation of three case reports and review of the current literature

    Directory of Open Access Journals (Sweden)

    Daša Kumprej

    2016-04-01

    Full Text Available Background: Henoch-Schönlein purpura is the most common vasculitis of small blood vessels in children. The diagnosis of the disease is confirmed in a patient with a specific rash, joint inflamation, abdominal pain or renal disease. The specific rash is necesary for the confirmation of the diagnosis. Henoch-Schönlein purpura can rarely present with a complication withot a prior presentation of the rash. In these cases diagnosis is difficult until the presentation of the specific skin manifestation. In the majority of patients the disease course is not complicated and has a good prognosis.Conclusion: In this article we present three patients with an atypical presentation of the disease and a review of current literature on the topic.

  14. Are the dental health needs of adults with illegal drug dependence being met by current service provision in the United Kingdom?: a literature review.

    Science.gov (United States)

    Hewson, Victoria; Wray, Jane

    2012-10-01

    This literature review outlines the current issues and debates relating to the dental health of adults with drug dependence. The dental health of adults with illegal drug dependence (IDD) continues to be under debate throughout dental practice, and the most appropriate model of care suitable to meet the high complex needs of this client group remains uncertain. The study aims to review and critically analyze available research relating to the oral health effects of illegal drug misuse and the dental health needs and status of adults with drug dependence. Second, it aims to identify and critically evaluate current models of dental service/care delivery, including relevant best practice guidance and potential barriers to dental access for adults with IDD. The available literature pertaining to dental health and adults with drug dependence are systematically reviewed and critically analyzed and evaluated in order to execute a rigorous investigation. The oral effects along with general medical complications associated with IDD are increasingly being recognized. There are substantive negative effects of IDD on oral health, particularly for those with opioid dependence; therefore, these clients have high complex dental needs and low use of dental services. Adults with drug dependence comprise a group with special dental needs and therefore need greater access to dental care than most people due to their high level of need. A high awareness of the implications for oral health care for adults with drug dependence is essential. Dental professionals have a key role in supporting the rehabilitation of these patients from potentially severe or fatal addictions. There is a distinct lack of national policy and guidance relating specifically to adults with drug dependence, and therefore, problems persist. Key findings and recommendations are presented to enhance the development of dental services for adults with IDD.

  15. Assessing dental students' competence: best practice recommendations in the performance assessment literature and investigation of current practices in predoctoral dental education.

    Science.gov (United States)

    Albino, Judith E N; Young, Stephen K; Neumann, Laura M; Kramer, Gene A; Andrieu, Sandra C; Henson, Lindsey; Horn, Bruce; Hendricson, William D

    2008-12-01

    In this article, the Task Force on Student Outcomes Assessment of the American Dental Education Association's Commission on Change and Innovation in Dental Education describes the current status of student outcomes assessment in U.S. dental education. This review is divided into six sections. The first summarizes the literature on assessment of dental students' performance. Section two discusses catalysts, with a focus on problem-based learning, for development of new assessment methods, while the third section presents several resources and guides that can be used to inform selection of assessment techniques for various domains of competence. The fourth section describes the methodology and results of a 2008 survey of current assessment practices in U.S. dental schools. In the fifth section, findings from this survey are discussed within the context of competency-based education, the educational model for the predoctoral curriculum endorsed by the American Dental Education Association and prescribed by the Commission on Dental Accreditation. The article concludes with a summary of assessments recommended as optimal strategies to measure three components of professional competence based on the triangulation model. The survey of assessment practices in predoctoral education was completed by 931 course directors, representing 45 percent of course directors nationwide, from fifty-three of the fifty-six U.S. dental schools. Survey findings indicate that five traditional mainstays of student performance evaluation-multiple-choice testing, lab practicals, daily grades, clinical competency exams, and procedural requirements-still comprise the primary assessment tools in dental education. The survey revealed that a group of newer assessment techniques, although frequently identified as best practices in the literature and commonly used in other areas of health professions education, are rarely employed in predoctoral dental education.

  16. New Approaches in Environmental Education: Current Developments in the Non-Scientific School Subjects of the Federal Republic of Germany--Results of a Research Project.

    Science.gov (United States)

    Lob, R. E.

    1989-01-01

    The traditional focus of environmental education (EE) in science and technology classes is criticized. EE instruction in the subjects of literature, art, music, home economics, textile design, career guidance, sports, history, political science, social studies, economics, philosophy, and religious instruction is proposed. (CW)

  17. A biologia em obras infantis de Monteiro Lobato: modulações literárias, científicas e culturais The Biology into monteiro lobato's child and teenage literature: literary, scientific and cultural modulations

    Directory of Open Access Journals (Sweden)

    Fabiana Aparecida de Carvalho

    2008-01-01

    between literature and biology and the intensity of the narrations that bring the beliefs, values and political interests in the scientific speech and that are brought into the literature in hybrid and nomad direction.

  18. Informing consumers about 'hidden' advertising. A literature review of the effects of disclosing sponsored content

    NARCIS (Netherlands)

    Boerman, S.C.; van Reijmersdal, E.A.; De Pelsmacker, P.

    2016-01-01

    This chapter provides an overview of what is currently known in the scientific literature about the effects of disclosures of sponsored content on consumers' responses. Methodology We provide a qualitative literature review of 21 empirical studies. Findings Awareness of disclosures is rather low, bu

  19. Conceptions of end users in current smart grid research and opportunities for further social scientific research on users in smart grids

    DEFF Research Database (Denmark)

    Larsen, Lars Ege

    there have been no attempts to handle it. This paper suggests that classifying the research contributions according to the roles they assign to users and the theoretical concepts they employ to represent users can help in evaluating the validity of their claims, uncovering possibilities for synthesis...... of existing knowledge and seeing new possibilities for social scientific research where knowledge gaps appear. Different user representations and user roles are found through a content analysis of project related documents from a selection of European and North American smart grid projects. It is argued...

  20. The future of the electronic scientific literature

    CERN Multimedia

    2001-01-01

    For electronic publishing to go forward, standards need to be developed but there also needs to be experimentation and flexibility in types of approach, to exploit the digital world to the full (2 pages).

  1. Beyond Keyword Search: Discovering Relevant Scientific Literature

    Science.gov (United States)

    2011-06-01

    12134 8490 9318 10372 Carl Nathan , MDnitrogen 10161 9318 Figure 5: Example illustrating trust calculation for an immunologist asking, “How much do I...trust Carl Nathan with respect to the concept ‘nitrogen’?” Thick dashed lines indicate influence from Dr. Nathan to individual elements of B, and pie...or Van Jacobson (computer networks), depending on who is answering. All are distinguished researchers, but each is associated with a distinct subfield

  2. "When can I return to driving?": a review of the current literature on returning to driving after lower limb injury or arthroplasty.

    Science.gov (United States)

    MacLeod, K; Lingham, A; Chatha, H; Lewis, J; Parkes, A; Grange, S; Smitham, P J

    2013-03-01

    Clinicians are often asked by patients, "When can I drive again?" after lower limb injury or surgery. This question is difficult to answer in the absence of any guidelines. This review aims to collate the currently available evidence and discuss the factors that influence the decision to allow a patient to return to driving. Medline, Web of Science, Scopus, and EMBASE were searched using the following terms: 'brake reaction time', 'brake response time', 'braking force', 'brake pedal force', 'resume driving', 'rate of application of force', 'driving after injury', 'joint replacement and driving', and 'fracture and driving'. Of the relevant literature identified, most studies used the brake reaction time and total brake time as the outcome measures. Varying recovery periods were proposed based on the type and severity of injury or surgery. Surveys of the Driver and Vehicle Licensing Agency, the Police, insurance companies in the United Kingdom and Orthopaedic Surgeons offered a variety of opinions. There is currently insufficient evidence for any authoritative body to determine fitness to drive. The lack of guidance could result in patients being withheld from driving for longer than is necessary, or returning to driving while still unsafe.

  3. On the Current Situation and Countermeasures of Uni-versity Students' Scientific Research Ability in Regular Undergraduate Universities%普通本科院校大学生科研能力现状及对策

    Institute of Scientific and Technical Information of China (English)

    赵靖伟; 何小杨

    2015-01-01

    随着社会对人才的需求不断提高,用人单位选人的标准除了学生学习成绩之外,越来越注重考察学生的实践能力和科研能力。培养大学生科研能力不仅成为市场的迫切需求,更是我国高校教育改革的一项重要目标。因此,本文在对学生科研能力的现状、问题进行调查与分析的基础上,进一步探讨培养大学生科研能力的对策。%With the continuous raise of social demands for talents, in addition to students' academic performance, employers pay more attention to students' practical ability and scientific research ability. The cultivation of university students' scientific research ability has become not only an urgent demand of the market, but also an important objective of China's university education re-form. Therefore, based on investigating and analyzing the current situation and problems of students' scientific research ability, this paper further explores countermeasures of cultivating university students' scientific research ability.

  4. 2005-2012年新疆医科大学科技文献发表情况分析%Analysis of Chinese scientific literatures published during the year of 2005 to 2012 by Xinjiang Medical University

    Institute of Scientific and Technical Information of China (English)

    郭建新; 熊道海; 朱晖; 耿庆玲; 张超; 张玲; 郭立群; 刘奎; 须玉红

    2014-01-01

    目的 分析新疆医科大学2005-2012年科研论文发表情况,为某校在科研管理和学科建设上提供重要的科学依据.方法 运用文献计量学的方法,对收录于CNKI《中国期刊全文数据库》2005-2012年新疆医科大学科技文献,从年度分布、文献刊载期刊、作者情况、学科分类、研究层次等方面进行统计分析.结果 2005-2012年新疆医科大学共发表中文论文18 004篇,其中中文核心期刊4 205篇.2012年发表论文数量是2005年的2.19倍,中文核心文献量是3.94倍,年平均增长速度1.12%.18 004篇论文刊载在1 190种期刊上,期刊平均发文量15篇.新疆刊物所占比例较大(70%).2005-2012年作者人数为7 270人,人均发文2.48篇.合作度为3.55.合著率92.86%.学科分布居前6位的是:肿瘤学、外科学、临床医学、中医学、心血管系统疾病、医学教育与医学边缘学科.研究层次,工程技术(自科)基础与应用基础研究(自科)这两项研究层次占据了发表文献的90%.结论 对揭示某校文献的发表规律,探讨科研的发展趋势,客观地评价科研工作的成就,促进科研工作的不断发展,具有重要的指导意义.%Objective Toanalizethe scientific literatures published during the year of 2005 to 2012 by Xinjiang Medical University for the reference of the scientific administration and discipline constructions.Methods Thesciientific literatures published during the year of 2005 to 2012 by Xinjiang Medical University included in CNKI were statistically analized on the year distribution,journals,authors,disciplines and research levelusing the methods of bibliometrics.Results Totally 18 004 manuscripts were published in Chinese by Xinjiang Medical University from 2005 to 2012,of which 4 205 were from Chinese core journals.The number of manuscripts published in 2012 was 2.19 times as many asthat of 2005,and 3.94 times in case of Chinese core journal with a mean increase of 1.12% per year

  5. How to respond to referee comments for scientific articles?

    Science.gov (United States)

    Kalemci, Mustafa Serdar; Turna, Burak

    2013-09-01

    Currently, the increasing number of article submissions to scientific journals forces editors to be more selective in their acceptance of papers. Consequently, editors have increased the frequency of their use of scientific referee mechanisms. For many researchers, the publication of a scientific article in a high impact factor journal is a gradual and difficult process. After preparation and submission of a manuscript, one of the most important issue is responding to the comments of referees. However, there is a paucity of published reports in the literature describing how to respond to these comments. The aim of this review is to assist researchers/authors in responding to referee comments as part of the publication process for scientific articles.

  6. Scientific communication

    Directory of Open Access Journals (Sweden)

    Aleksander Kobylarek

    2017-09-01

    Full Text Available The article tackles the problem of models of communication in science. The formal division of communication processes into oral and written does not resolve the problem of attitude. The author defines successful communication as a win-win game, based on the respect and equality of the partners, regardless of their position in the world of science. The core characteristics of the process of scientific communication are indicated , such as openness, fairness, support, and creation. The task of creating the right atmosphere for science communication belongs to moderators, who should not allow privilege and differentiation of position to affect scientific communication processes.

  7. Optimizing fitness for duty and post-combat clinical services for military personnel and combat veterans with ADHD—a systematic review of the current literature

    Directory of Open Access Journals (Sweden)

    Iliyan Ivanov

    2014-08-01

    Full Text Available Background: Attention deficit hyper activity disorder (ADHD is a developmental disorder, most often diagnosed in childhood, and characterized by hyperactivity and inattention that negatively impacts one's ability to function and fulfill social and personal obligations. Individuals with past history of ADHD may enlist in the military under certain conditions, however the full impact of military training and deployment of later in life ADHD symptoms is unclear. It is of particular interest how military experience may affect ADHD in remission and if such individuals might be at elevated risk for relapse of ADHD symptoms. Method: We performed a systematic review f the available literature including the Department of Defense (DOD guidelines for both eligibility to enlist and fitness for deployment based on reported history and current symptomatology of ADHD. Results: The after care for veterans with ADHD relapse is inconsistent and presents with number of challenges. We evaluate the DOD policies regarding the implications of ADHD for fitness for military service and post-combat mental health. Conclusion: The full extend of the interaction between pre-existing ADHD and post-combat PTSD are not fully understood. The development of comprehensive and clear algorithms for diagnosing and treating ADHD in the military before and after deployment will have a strong positive impact on the quality of care delivered to soldiers and veterans.

  8. Rapid acquisition and modulation of colistin-resistance by an extensively drug-resistant Acinetobacter baumannii: case report and review of current literature

    Directory of Open Access Journals (Sweden)

    Jari Intra

    2016-10-01

    Full Text Available Acinetobacter baumannii has emerged as a major cause of healthcare-associated infections. It commonly expresses clinical resistance to multiple antimicrobial agents, and hence, it is considered the paradigm of an extensively drug-resistant (XDR bacterium. XDR A. baumannii is a rapidly emerging pathogen, especially in the intensive care unit (ICU, causing nosocomial infections including sepsis, ventilatorassociated pneumonia, meningitis, peritonitis, urinary tract infection, and central venous catheter-related infection. In the present report, we described an in vivo evolution of A. baumannii strain from a colistinsusceptibility to a colistin-resistance state. A 65-year-old male, who suffered a duodenal ulcer, two days after hospitalization and during the stay in ICU, contracted a pneumonia and peritoneal infection by a carbapenem-resistant A. baumannii strain. After a combination treatment with colistin, vancomycin plus imipenem, and within seven days, the pathogen rapidly evolved in seven days to a pandrug-resistant phenotype. As the antimicrobial treatment was stopped, the A. baumannii isolate changed another time its profile to colistin, becoming newly susceptible, showing a very high level of adaptability to external conditions. We also have reviewed here the current literature on this worryingly public health threat.

  9. Current Scientific and Regulatory Approaches for Development of Orally Inhaled and Nasal Drug Products: Overview of the IPAC-RS/University of Florida Orlando Inhalation Conference.

    Science.gov (United States)

    Hochhaus, Guenther; Davis-Cutting, Craig; Oliver, Martin; Lee, Sau L; Lyapustina, Svetlana

    2015-09-01

    This article summarizes discussions at the March 2014 conference organized by the University of Florida (UF) and International Pharmaceutical Aerosol Consortium on Regulation and Science (IPAC-RS), entitled "Orlando Inhalation Conference: Approaches in International Regulation." The special focus of the conference was on global scientific and regulatory issues associated with the testing and demonstration of equivalence for the registration of orally inhaled drug products (OIDPs) in the United States, Europe, Brazil, China, and India. The scope included all types of OIDPs throughout their lifecycle, e.g., innovator/brand-name products, generics, modifications due to lifecycle management, device changes, etc. Details were presented for the U.S. "weight of evidence approach" for registration of generic products (which includes demonstration of in vitro and in vivo equivalence, as well as quantitative and qualitative sameness, and device similarity). The European "stepwise" approach was elucidated, and the thinking of regulatory agencies in the major emerging markets was clarified. The conference also highlighted a number of areas that would benefit from further research and discussion, especially around patient/device interface and human factor studies, statistical methods and criteria for demonstrating equivalence, the relative roles of in vivo and in vitro tests, and appropriate designs and metrics for in vivo studies of inhaled drugs.

  10. The effect of scientific evidence on conservation practitioners' management decisions.

    Science.gov (United States)

    Walsh, Jessica C; Dicks, Lynn V; Sutherland, William J

    2015-02-01

    A major justification of environmental management research is that it helps practitioners, yet previous studies show it is rarely used to inform their decisions. We tested whether conservation practitioners focusing on bird management were willing to use a synopsis of relevant scientific literature to inform their management decisions. This allowed us to examine whether the limited use of scientific information in management is due to a lack of access to the scientific literature or whether it is because practitioners are either not interested or unable to incorporate the research into their decisions. In on-line surveys, we asked 92 conservation managers, predominantly from Australia, New Zealand, and the United Kingdom, to provide opinions on 28 management techniques that could be applied to reduce predation on birds. We asked their opinions before and after giving them a summary of the literature about the interventions' effectiveness. We scored the overall effectiveness and certainty of evidence for each intervention through an expert elicitation process-the Delphi method. We used the effectiveness scores to assess the practitioners' level of understanding and awareness of the literature. On average, each survey participant changed their likelihood of using 45.7% of the interventions after reading the synopsis of the evidence. They were more likely to implement effective interventions and avoid ineffective actions, suggesting that their intended future management strategies may be more successful than current practice. More experienced practitioners were less likely to change their management practices than those with less experience, even though they were not more aware of the existing scientific information than less experienced practitioners. The practitioners' willingness to change their management choices when provided with summarized scientific evidence suggests that improved accessibility to scientific information would benefit conservation management

  11. Scientific/Techical Report

    Energy Technology Data Exchange (ETDEWEB)

    Dr. Chris Leighton, Neutron Scattering Society of American; Mr. J. Ardie (Butch) Dillen, MRS Director of Finance and Administration

    2012-11-07

    The ACNS provides a focal point for the North American neutron user community, strengthening ties within this diverse group, and promoting neutron research in related disciplines. The conference thus serves a dual role as both a national user meeting and a scientific meeting. As a venue for scientific exchange, the ACNS showcases recent results and provides a forum for scientific discussion of neutron-enabled research in fields as diverse as hard and soft condensed matter, liquids, biology, magnetism, engineering materials, chemical spectroscopy, crystal structure, elementary excitations, fundamental physics, and development of neutron instrumentation. This is achieved through a combination of invited oral presentations, contributed oral presentations, and poster sessions. Adequate opportunity for spontaneous discussion and collaboration is also built into the ACNS program in order to foster free exchange of new scientific ideas and the potential for use of powerful neutron scattering methods beyond the current realms of application. The sixth American Conference on Neutron Scattering (ACNS 2012) provided essential information on the breadth and depth of current neutron-related research worldwide. A strong program of plenary, invited and contributed talks showcased recent scientific results in neutron science in a wide range of fields, including soft and hard condensed matter, biology, chemistry, energy and engineering applications, and neutron physics.

  12. Current scientific evidence for integrated community case management (iCCM in Africa: Findings from the iCCM Evidence Symposium

    Directory of Open Access Journals (Sweden)

    Theresa Diaz

    2014-11-01

    Full Text Available In March 2014, over 400 individuals from 35 countries in sub-Saharan Africa and 59 international partner organizations gathered in Accra, Ghana for an integrated Community Case Management (iCCM Evidence Review Symposium. The objective was 2-fold: first, to review the current state of the art of iCCM implementation and second, to assist African countries to integrate lessons learned and best practices presented during the symposium into their programmes. Based on the findings from the symposium this supplement includes a comprehensive set of articles that provide the latest evidence for improving iCCM programs and ways to better monitor and evaluate such programs

  13. Diagnosis and treatment of fetal cardiac disease: A scientific statement from the american heart association

    OpenAIRE

    Donofrio, MT; Moon-Grady, AJ; Hornberger, LK; Copel, JA; Sklansky, MS; Abuhamad, A; Cuneo, BF; Huhta, JC; Jonas, RA; Krishnan, A.; Lacey, S; W. Lee; Michelfelder, EC; Rempel, GR; Silverman, NH

    2014-01-01

    Background - The goal of this statement is to review available literature and to put forth a scientific statement on the current practice of fetal cardiac medicine, including the diagnosis and management of fetal cardiovascular disease. Methods and Results - A writing group appointed by the American Heart Association reviewed the available literature pertaining to topics relevant to fetal cardiac medicine, including the diagnosis of congenital heart disease and arrhythmias, assessment of card...

  14. Scientific evidence on the usefulness of intraarticular hyaluronic acid injection in the management of temporomandibular dysfunction

    OpenAIRE

    Escoda Francolí, Jaume; Vázquez Delgado, Eduardo; Gay Escoda, Cosme

    2010-01-01

    Hyaluronic acid (HA) is found in high concentrations in cartilage and synovial fluid, and is an important component of the extracellular matrixes- exerting joint lubrication and buffering actions thanks to its viscoelastic properties. The present study examines the scientific evidence found in the current literature on the usefulness of the intraarticular injection of HA in patients with temporomandibular dysfunction. A literature search was made up until May 2008 in the following databases: ...

  15. Collation of Scientific Evidence on Consumer Acceptance of New Food Technologies: Three roads to consumer choice

    NARCIS (Netherlands)

    Fischer, A.R.H.; Trijp, van J.C.M.; Hofenk, D.J.B.; Ronteltap, A.; Tudoran, A.A.

    2012-01-01

    The current report investigates consumer acceptance of new food technologies by reviewing the scientific literature. The review is organised along three routes to consumer acceptance of new technologies: The consumer benefit road: the central road of technology features influencing experienced produ

  16. INVESTIGACIÓN CLÍNICA EN FONOAUDIOLOGÍA: ANÁLISIS DE LA LITERATURA CIENTÍFICA 2005-2009 Research in language therapy: an analysis of scientific literature 2005-2009

    Directory of Open Access Journals (Sweden)

    Janeth Hernández-Jaramillo

    2010-07-01

    .Background. There are few scientometric studies in speech pathology and audiology and therefore there is no evidence of the focus areas of research, as well as trends and behavior over time. Objective. Analyze the scientific production of clinical research in audiology, between 2005 and 2009, to characterize the bibliometric production and identify trends and growth in clinical research; to study the dispersion of the scientific literature and identify research cooperation. Material and methods. We analyzed the production of scientific literature clinical research in audiology areas, registered in PubMed-MEDLINE from the years 2005 to 2009. Results. We considered a total of 4127 publications. The analysis showed a higher number of publications for language and language disorders area, followed by hearing and hearing disorders and papers related to the swallowing and its disorders, in contrast to the fields stuttering and aural rehabilitation yielded the lowest values. No significant differences were comparatively in the number of publications between years. We noted an increased production of secondary epidemiological studies compared to clinical studies, however, clinical studies accounted for 42% of total publications and of these 42,4% were consistent with randomized trials. Most of the researchers were faculties affiliated, followed by health institutions and cooperation between both. Independent researchers and unconsolidated research networks presented the lower percentage of publications. Conclusions. The findings suggest that the capacity of audiologists to develop quality research, use, and transfer its results into clinical practice should achieve greater development

  17. Scientific citations in Wikipedia

    CERN Document Server

    Nielsen, Finn Aarup

    2007-01-01

    The Internet-based encyclopaedia Wikipedia has grown to become one of the most visited web-sites on the Internet. However, critics have questioned the quality of entries, and an empirical study has shown Wikipedia to contain errors in a 2005 sample of science entries. Biased coverage and lack of sources are among the "Wikipedia risks". The present work describes a simple assessment of these aspects by examining the outbound links from Wikipedia articles to articles in scientific journals with a comparison against journal statistics from Journal Citation Reports such as impact factors. The results show an increasing use of structured citation markup and good agreement with the citation pattern seen in the scientific literature though with a slight tendency to cite articles in high-impact journals such as Nature and Science. These results increase confidence in Wikipedia as an good information organizer for science in general.

  18. Scientific Auditing Firms

    CERN Document Server

    Sarma, Gopal P

    2016-01-01

    The "crisis of reproducibility" has been a significant source of controversy, heated debate, and calls for reform to institutional science in recent years. As a long-term solution to address both the present crisis and future obstacles, I propose the creation of a new form of research organization whose purpose would be to conduct random audits of the scientific literature. I suggest that data analytics of a digitized scientific corpus may play a critical role in allowing broadly educated scientists to identify linchpin results to investigate in further detail across all disciplines. I argue that a simple "mock" trial run of a simplified auditing firm consisting of several researchers over a short time period would provide valuable insight into the feasibility of this proposal.

  19. Etiquette in scientific publishing.

    Science.gov (United States)

    Krishnan, Vinod

    2013-10-01

    Publishing a scientific article in a journal with a high impact factor and a good reputation is considered prestigious among one's peer group and an essential achievement for career progression. In the drive to get their work published, researchers can forget, either intentionally or unintentionally, the ethics that should be followed in scientific publishing. In an environment where "publish or perish" rules the day, some authors might be tempted to bend or break rules. This special article is intended to raise awareness among orthodontic journal editors, authors, and readers about the types of scientific misconduct in the current publishing scenario and to provide insight into the ways these misconducts are managed by the Committee of Publishing Ethics. Case studies are presented, and various plagiarism detection software programs used by publishing companies are briefly described.

  20. Scientific Growth

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    As one of the world's largest grain consumers,food security has always been a major concern for the Chinese nation.China must confront the challenge of feeding a fifth of the world's population with less than 9 percent of the planet's arable land.In 2011,China's grain output recorded growth for the eighth successive year,and total production reached an all-time high of 571million tons.In terms of food security,China's goal is to maintain a self-sufficiency rate of above 95 percent.However,an annual net population growth of 7.39 million and the effective decline of the area of farmland in the country,as a result of urbanization,make achieving such selfsufficiency a serious challenge.Given the heavy burden placed on Chinese agriculture,constantly raising productivity by relying on scientific and technological progress has become a priority for China's agricultural sector.The Ministry of Agriculture,for example,has worked to raise China's annual grain yield per-unit area by 1 percent,on average,over the past decade.Last year,the contributory rate of scientific and technological development to China's agriculture reached 52 percent,surpassing the contribution made by land,labor and other production factors for the first time in history.

  1. Mortalidade materna no Brasil: o que mostra a produção científica nos últimos 30 anos? Maternal mortality in Brazil: what has the scientific literature shown in the last 30 years?

    Directory of Open Access Journals (Sweden)

    Marcia Lait Morse

    2011-04-01

    Full Text Available O objetivo deste trabalho foi descrever o perfil epidemiológico e a tendência da mortalidade materna no Brasil, por meio de revisão de estudos sobre o tema. Foi realizada busca eletrônica de artigos científicos publicados entre 1980 e 2010, nas bases de dados LILACS e MEDLINE. Identificaram-se inicialmente 486 artigos. Após aplicação dos critérios de inclusão e exclusão restaram 50 artigos. A comparação dos dados mostrou queda da RMM de forma diferenciada nas regiões brasileiras. Os estudos sobre determinação do óbito materno apontaram desigualdades sociais relacionadas à cor da pele e escolaridade. O preenchimento incompleto da declaração de óbito e a subnotificação ainda persistem. Prevaleceram as causas obstétricas diretas, com predomínio das doenças hipertensivas. Quando analisada, a evitabilidade apontou falhas na assistência pré-natal e ao parto. Apesar de sua relevância, são poucos os artigos sobre mortalidade materna no Brasil. A RMM, embora em declínio, permanece em níveis elevados. Melhorias na qualidade da assistência pré-natal e ao parto são necessárias.The aim of this study was to analyze maternal mortality in Brazil in the last 30 years, by means of a literature review. The authors performed an electronic search of scientific articles from 1980 to 2010 in LILACS and MEDLINE and found 486 abstracts, of which 50 articles were selected. Studies showed a decrease in the maternal mortality ratio (MMR, although varying across regions of the country. A few articles evaluated maternal mortality factors, identifying social inequalities associated with skin color and schooling. There was persistent underreporting of maternal deaths and inadequate completion of death certificates. Direct obstetric causes were the most frequent, mainly hypertensive diseases of pregnancy. Analysis of avoidability revealed deficiencies in prenatal and childbirth care. Despite the relevance of maternal mortality in Brazil

  2. Burden of road traffic injuries and related risk factors in low and middle-income Pacific Island countries and territories: a systematic review of the scientific literature (TRIP 5).

    Science.gov (United States)

    Herman, Josephine; Ameratunga, Shanthi; Jackson, Rod

    2012-06-25

    In Pacific Island countries and territories, the burden of road traffic injuries and their attendant risks are considered significant but are poorly quantified. As with other low and middle-income countries, understanding the epidemiology of road traffic injuries in Pacific countries is critical to informing sustainable research and policy initiatives aimed at reducing this burden. We undertook a systematic review and critical appraisal of the relevant epidemiological literature between January 1980 and December 2010, using key search strings for incidence and aetiological studies focusing on RTIs in less resourced Pacific countries. Nineteen studies were identified. The majority were descriptive and were unable to provide population-based estimates of the burden of road crash injury, or reliable information on risk factors using well-designed aetiological research methods. All studies were published more than 10 years ago, and all but three reported on data from Papua New Guinea, thereby limiting the generalisability of findings to the current status in the region. Studies undertaken in Papua New Guinea suggested that RTIs were more frequent among young males, with head injuries the most common cause of death or hospital admission. Two thirds of fatalities occurred at the crash site or soon after admission. Most road crash victims were passengers or pedestrians. Factors postulated to influence the risk of RTIs were travel in open-back utility vehicles, utility vehicle overcrowding, and alcohol. This review suggests that, despite increasing awareness of the importance of addressing road safety among stakeholders in less resourced Pacific Island countries, road traffic injuries have not been a research priority with little relevant current evidence from the region to inform policy. Robust epidemiological research that can assess the magnitude and key determinants of road traffic injuries in these settings is essential to determine context-specific road safety

  3. African Literature

    OpenAIRE

    Recek, Denis

    2011-01-01

    The topic of this diploma is the formation and shaping of African literature. The first chapter is about the beginning of African literature. It describes oral literature and its transmission into written literature. Written African literature had great problems in becoming a part of world literature because of its diversity of languages and dialects. Christianity and Islam are mentioned as two religions which had a great impact on African literature. Colonialism is broadly described as an es...

  4. Role of Scientific Societies in International Collaboration

    Science.gov (United States)

    Fucugauchi, J. U.

    2007-12-01

    Geophysical research increasingly requires global multidisciplinary approaches. Understanding how deeply interrelated are Earth components and processes, population growth, increased needs of mineral and energy resources, global impact of human activities, and view of our planet as an interconnected system emphasizes the need of international cooperation. International research collaboration has an immense potential and is needed for further development of Earth science research and education. The Union Session is planned to provide a forum for analysis and discussion of the status of research and education of geosciences in developing countries, international collaboration programs and new initiatives for promoting and strengthening scientific cooperation. A theme of particular relevance in the analyses and discussions is the role of scientific societies in international collaboration. Societies organize meetings, publish journals and books and promote cooperation through academic exchange activities. They may further assist communities in developing countries in providing and facilitating access to scientific literature, attendance to international meetings, short and long-term stays and student and young researcher mobility. What else can be done? This is a complex subject and scientific societies may not be seen independently from the many factors involved in research and education. Developing countries present additional challenges resulting from limited economic resources and social and political problems, while urgently requiring improved educational and research programs. Needed are in-depth analyses of infrastructure and human resources, and identification of major problems and needs. What are the major limitations and needs in research and postgraduate education in developing countries? What and how should international collaboration do? What are the roles of individuals, academic institutions, funding agencies, scientific societies? Here we attempt to

  5. Current Status on Flood Forecasting and Early Warning in Africa

    NARCIS (Netherlands)

    Thiemig, V.; Roo, A.P.J. de

    2011-01-01

    An overview of the current state of flood forecasting and early warning in Africa is provided in order to identify future user needs and research. Information was collected by reviewing previously published research in the scientific literature and from institutional websites. This information was

  6. Current Status on Flood Forecasting and Early Warning in Africa

    NARCIS (Netherlands)

    Thiemig, V.; Roo, A.P.J. de

    2011-01-01

    An overview of the current state of flood forecasting and early warning in Africa is provided in order to identify future user needs and research. Information was collected by reviewing previously published research in the scientific literature and from institutional websites. This information was s

  7. Current Status on Flood Forecasting and Early Warning in Africa

    NARCIS (Netherlands)

    Thiemig, V.; Roo, A.P.J. de

    2011-01-01

    An overview of the current state of flood forecasting and early warning in Africa is provided in order to identify future user needs and research. Information was collected by reviewing previously published research in the scientific literature and from institutional websites. This information was s

  8. The spacelab scientific missions: A comprehensive bibliography of scientific publications

    Science.gov (United States)

    Torr, Marsha (Compiler)

    1995-01-01

    November 1993 represented the 10-year anniversary of the flight of Spacelab 1 mission, with the first precursor mission (OSTA-1) being launched 2 years earlier. Since that time, a total of 27 Shuttle missions has been flown, using the Spacelab system as a facility for conducting scientific research in space. The missions flown to date have allowed a total of approximately 500 Principle Investigator class investigations to be conducted in orbit. These investigations have constituted major scientific efforts in astronomy/astrophysics, atmospheric science, Earth observation, life sciences, microgravity science, and space plasma physics. An initial survey of the scientific products gleaned from Spacelab missions already flown was sent to the Principle Investigators. In that survey, information was gathered from the investigators on the scientific highlights of their investigations and statistical measurements of overall success -- such as papers published. This document is a compilation of the papers that have been published to date in referred literature.

  9. Fairness in scientific publishing

    Science.gov (United States)

    Matthews, Philippa C.

    2017-01-01

    Major changes are afoot in the world of academic publishing, exemplified by innovations in publishing platforms, new approaches to metrics, improvements in our approach to peer review, and a focus on developing and encouraging open access to scientific literature and data. The FAIR acronym recommends that authors and publishers should aim to make their output Findable, Accessible, Interoperable and Reusable. In this opinion article, I explore the parallel view that we should take a collective stance on making the dissemination of scientific data fair in the conventional sense, by being mindful of equity and justice for patients, clinicians, academics, publishers, funders and academic institutions. The views I represent are founded on oral and written dialogue with clinicians, academics and the publishing industry. Further progress is needed to improve collaboration and dialogue between these groups, to reduce misinterpretation of metrics, to minimise inequity that arises as a consequence of geographic setting, to improve economic sustainability, and to broaden the spectrum, scope, and diversity of scientific publication.

  10. Burden of road traffic injuries and related risk factors in low and middle-income Pacific Island countries and territories: a systematic review of the scientific literature (TRIP 5

    Directory of Open Access Journals (Sweden)

    Herman Josephine

    2012-06-01

    Full Text Available Abstract Background In Pacific Island countries and territories, the burden of road traffic injuries and their attendant risks are considered significant but are poorly quantified. As with other low and middle-income countries, understanding the epidemiology of road traffic injuries in Pacific countries is critical to informing sustainable research and policy initiatives aimed at reducing this burden. Methods We undertook a systematic review and critical appraisal of the relevant epidemiological literature between January 1980 and December 2010, using key search strings for incidence and aetiological studies focusing on RTIs in less resourced Pacific countries. Results Nineteen studies were identified. The majority were descriptive and were unable to provide population-based estimates of the burden of road crash injury, or reliable information on risk factors using well-designed aetiological research methods. All studies were published more than 10 years ago, and all but three reported on data from Papua New Guinea, thereby limiting the generalisability of findings to the current status in the region. Studies undertaken in Papua New Guinea suggested that RTIs were more frequent among young males, with head injuries the most common cause of death or hospital admission. Two thirds of fatalities occurred at the crash site or soon after admission. Most road crash victims were passengers or pedestrians. Factors postulated to influence the risk of RTIs were travel in open-back utility vehicles, utility vehicle overcrowding, and alcohol. Conclusions This review suggests that, despite increasing awareness of the importance of addressing road safety among stakeholders in less resourced Pacific Island countries, road traffic injuries have not been a research priority with little relevant current evidence from the region to inform policy. Robust epidemiological research that can assess the magnitude and key determinants of road traffic injuries in these

  11. A unifying vision for scientific decision making: the Academy of Nutrition and Dietetics' Scientific Integrity Principles.

    Science.gov (United States)

    Tappenden, Kelly A

    2015-09-01

    In 2014, recognizing the need to have a single document to guide scientific decision making at the Academy of Nutrition and Dietetics (Academy), the Council on Research was charged with developing a scientific integrity policy for the organization. From the Council on Research, four members volunteered to lead this workgroup, which reviewed the literature and best practices for scientific integrity from well-respected organizations, including federal funders of research. It became clear that the scope of this document would be quite broad, given the many scientific activities the Academy is involved in, and that it would be unreasonable to set policy for each of these many situations. Therefore, the workgroup set about defining the scope of scientific activities to be covered and envisioned a set of guiding principles, to which policies from every organizational unit of the Academy could be compared to ensure they were in alignment. While many relevant policies exist already, such as the requirement of a signed conflict of interest disclosure for Food & Nutrition Conference & Expo speakers, the Evidence Analysis Library funding policy, and the Academy's sponsorship policy, the scientific integrity principals are unique in that they provide a unifying vision to which future policies can be compared and approved based on their alignment with the principles. The six principles outlined in this article were approved by the full Council on Research in January 2015 and approved by the Academy's Board of Directors in March 2015. This article covers the scope of the principles, presents the principles and existing related resources, and outlines next steps for the Academy to review and revise current policies and create new ones in alignment with these principles. Copyright © 2015 Academy of Nutrition and Dietetics. Published by Elsevier Inc. All rights reserved.

  12. Proposed scientific activities for the Salton Sea Scientific Drilling Project

    Energy Technology Data Exchange (ETDEWEB)

    1984-05-01

    The Salton Sea Scientific Drilling Project (SSSDP) has been organized for the purpose of investigating a hydrothermal system at depths and temperatures greater than has been done before. Plans are to deepen an existing well or to drill a new well for research purposes for which temperatures of 300/sup 0/C will be reached at a depth of less than 3.7 km and then deepen that well a further 1.8 km. This report recounts the Congressional history of the appropriation to drill the hole and other history through March 1984, gives a review of the literature on the Salton Sea Geothermal Field and its relationship to other geothermal systems of the Salton Trough, and describes a comprehensive series of investigations that have been proposed either in the well or in conjunction with the SSSDP. Investigations in geophysics, geochemistry and petrology, tectonics and rock mechanics, and geohydrology are given. A tabulation is given of current commercial and state-of-the-art downhole tools and their pressure, temperature, and minimum hole size limitations.

  13. Neurology and literature 2.

    Science.gov (United States)

    Iniesta, I

    2014-05-01

    Good literary fiction has the potential to move us, extend our sense of life, transform our prospective views and help us in the face of adversity. A neurological disorder is likely to be the most challenging experience a human being may have to confront in a lifetime. As such, literary recreations of illnesses have a doubly powerful effect. Study the synergies between neurology and fictional literature with particular reference to narrative based medicine (NBM). Doctors establish boundaries between the normal and the abnormal. Taking a clinical history is an act of interpretation in which the doctor integrates the science of objective signs and measurable quantities with the art of subjective clinical judgment. The more discrepancy there is between the patient's experience with the illness and the doctor's interpretation of that disease, the less likely the doctor-patient interaction is to succeed. NBM contributes to a better discernment of the meanings, thus considering disease as a biographical event rather than just a natural fact. Drawing from their own experience with disease, writers of fiction provide universal insights through their narratives, whilst neuroscientists, like Cajal, have occasionally devoted their scientific knowledge to literary narratives. Furthermore, neurologists from Alzheimer to Oliver Sacks remind us of the essential value of NBM in the clinic. Integrating NBM (the narrative of patients) and the classic holistic approach to patients with our current paradigm of evidence based medicine represents a challenge as relevant to neurologists as keeping up with technological and scientific advances. Copyright © 2011 Sociedad Española de Neurología. Published by Elsevier Espana. All rights reserved.

  14. Scientific Eschatology

    CERN Document Server

    Noyes, H P; Lindesay, James

    2005-01-01

    The future evolution of the universe suggested by the cosmological model proposed earlier at this meeting by the authors is explored. The fundamental role played by the positive "cosmological constant" is emphasized. Dyson's 1979 paper entitled "Time Without End" is briefly reviewed. His most optimistic scenario requires that the universe be geometrically open and that biology is structural in the sense that the current complexity of human society can be reproduced by scaling up its (quantum mechanical) structure to arbitrary size. If the recently measured "cosmological constant" is indeed a fundamental constant of nature, then Dyson's scenario is, for various reasons, ruled out by the finite (De Sitter) horizon due to exponential expansion of the resulting space. However, the finite temperature of that horizon does open other interesting options. If, as is suggested by the cosmology under consideration, the current exponential expansion of the universe is due to a phase transition which fixes a physical boun...

  15. SCIENTIFIC STATUS OF DIDACTICS

    Directory of Open Access Journals (Sweden)

    I. M. Osmolovskaya

    2015-03-01

    Full Text Available The research is aimed at scientific justification of didactics referred to the social and humanitarian field of knowledge. The author deals with the scientific character criteria (verity, inter-subjectivity, systemacity and validity taking into account different scientific rationality types (classical and nonclassical and identifying post-modernism influence on didactics. Objectives and results of research. Attempts are made to systematize the didactic knowledge and identify its components and structure. Didactic concepts are classified in accordance with its objects: teaching process by the whole, its individual components or educative process aspects that enable to form definite teaching views, studying it from the specific positions. The author singles out holistic-didactic, component and aspect concepts; and specifies the concept of didactic systems and models with its hierarchy. The author highlights the didactic knowledge increment. Apart from traditional empirical theoretical researches, the author’s attention is drawn to the academic pursuit such as a scientific project based on the didactic object specificity of the teaching process which is fully human controlled and realized and doesn’texist without human being. It is shown that basic theoretical ideas of scientific projects are itemized, concretized and enlarged during co-current educative practice, i.e. an adhesion of theory and practice occurs.It is stressed that there are two special directions of didactic development multidimensionality: 1. extension of its semantic field in the context of modern socio-cultural conditions; 2. increase of scientific status related to a conceptual framework improvement, empirically accumulated information arrangement, new hypotheses, theories and concepts’ development. Scientific novelty. The research findings demonstrate well-reasoned statement of the didactics’ scientific status, its particular components and structure

  16. SCIENTIFIC STATUS OF DIDACTICS

    Directory of Open Access Journals (Sweden)

    I. M. Osmolovskaya

    2014-01-01

    Full Text Available The research is aimed at scientific justification of didactics referred to the social and humanitarian field of knowledge. The author deals with the scientific character criteria (verity, inter-subjectivity, systemacity and validity taking into account different scientific rationality types (classical and nonclassical and identifying post-modernism influence on didactics. Objectives and results of research. Attempts are made to systematize the didactic knowledge and identify its components and structure. Didactic concepts are classified in accordance with its objects: teaching process by the whole, its individual components or educative process aspects that enable to form definite teaching views, studying it from the specific positions. The author singles out holistic-didactic, component and aspect concepts; and specifies the concept of didactic systems and models with its hierarchy. The author highlights the didactic knowledge increment. Apart from traditional empirical theoretical researches, the author’s attention is drawn to the academic pursuit such as a scientific project based on the didactic object specificity of the teaching process which is fully human controlled and realized and doesn’texist without human being. It is shown that basic theoretical ideas of scientific projects are itemized, concretized and enlarged during co-current educative practice, i.e. an adhesion of theory and practice occurs.It is stressed that there are two special directions of didactic development multidimensionality: 1. extension of its semantic field in the context of modern socio-cultural conditions; 2. increase of scientific status related to a conceptual framework improvement, empirically accumulated information arrangement, new hypotheses, theories and concepts’ development. Scientific novelty. The research findings demonstrate well-reasoned statement of the didactics’ scientific status, its particular components and structure

  17. Tire Crumb Research Study Literature Review / Gap ...

    Science.gov (United States)

    In order to more fully understand data gaps in human exposure and toxicity to tire crumb materials, ATSDR, CPSC and EPA undertook a collaborative effort in the form of a scientific literature review and subsequent gaps analysis. The first objective of the Literature Review and Gap Analysis (LRGA) collaboration was to identify the existing body of literature related specifically to human exposure to tire crumb materials through the use of synthetic turf athletic fields and playgrounds. The second objective was to characterize and summarize the relevant data from the scientific literature. The final objective was to review the summary information and identify data gaps to build on the current understanding of the state-of-the-science and inform the development of specific research efforts that would be most impactful in the near-term. Because of the need for additional information, the U.S. Environmental Protection Agency (EPA), the Centers for Disease Control and Prevention/Agency for Toxic Substances and Disease Registry (ATSDR), and the U.S. Consumer Product Safety Commission (CPSC) launched a multi-agency action plan to study key environmental human health questions. The Federal Research Action Plan includes numerous activities, including research studies (U.S. EPA, 2016). A key objective of the Action Plan is to identify key knowledge gaps.

  18. 78 FR 57159 - Scientific Information Request on Medication Therapy Management

    Science.gov (United States)

    2013-09-17

    ... HUMAN SERVICES Agency for Healthcare Research and Quality Scientific Information Request on Medication... scientific information submissions from the public on medication therapy management Scientific information is being solicited to inform our review of Medication Therapy Management, which is currently...

  19. Spatial Analysis on the Geographical Information of the Scientific Literatures for Qinghai-Tibet Plateau%青藏高原科研文献地理信息空间分析研究

    Institute of Scientific and Technical Information of China (English)

    王雪梅; 李新; 马明国; 张志强

    2012-01-01

    多学科的协同、渗透、交叉已成为当代科学发展的重要趋势,文献计量学和地理信息系统(GIS)技术的集成是拓展GIS应用领域的一个新兴方向。许多与地理空间位置有关的信息包含在大量地学科研文献中。从CNKI文献数据库收录的研究青藏高原的科研文献中提取研究区、样带和采样点等位置相关信息,运用GIS技术进行空间分析和展现。结果显示,青藏高原研究的主要学科领域集中在生态环境及其变化、地质与地球物理特征及其演化、资源及其勘探、地质工程等方面。有关青藏高原的研究在空间分布上存在较大的差异,对青藏高原的研究从西南、西北到东南、东北区域,其受关注的程度逐渐增加。祁连山脉、羌塘高原、青海湖、青藏公路、青藏铁路和川藏公路等是研究的热点区域。沿经度和纬度方向不同区间研究的分布也不同,研究热点区域呈现出从青藏高原中部向东北部转移的趋势。多数采样点和观测点沿交通干线分布,并且随着与交通干线距离的增加数量明显减少。GIS技术在关于青藏高原的文献计量分析中得到了有效应用,有助于挖掘出大量与空间位置相关的信息,从而深入分析青藏高原研究的发展态势。%The multi-disciplinary cooperation and intersection becomes the main development tendency of the modern sciences.It is a new direction to expand the Geographical Information System(GIS) application areas by integrating the GIS technologies with Bibliometrics.A lot of geographic-related information is involved in the literatures concerned with geosciences normally involve some geo-science references.In this paper,the location-related information(e.g.study areas,sampling trips and sampling points) was extracted from the CNKI-indexed scientific literatures for Qinghai-Tibet Plateau.These data were spatially analyzed and presented by using the GIS technologies

  20. Promoting Scientific Spirit to Cultivate Scientific Culture

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    Scientific culture is an advanced culture that is based on scientific knowledge and supported by the scientific method, with scientific thinking as its core and scientific spirit as its soul. During the process of modernization, it has profound impacts on human society in terms of values, ethics, mode of thinking, lifestyle and code of conduct, offering human civilization an important ideological source, physical foundation, technological tool and effective carrier.

  1. Scientific Opinion on the evaluation of the substances currently on the list in the annex to Commission Directive 96/3/EC as acceptable previous cargoes for edible fats and oils – Part III of III

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Contaminants in the Food Chain (CONTAM

    2012-12-01

    Full Text Available Shipping of edible fats and oils into Europe is permitted in bulk tanks, in which substances, included in a positive list, had been previously transported. The European Commission requested EFSA to evaluate the list of substances in the Annex to Commission Directive 96/3/EC as acceptable previous cargoes for edible fats and oils, taking into account its review of the Scientific Committee on Food criteria for acceptable previous cargoes and criteria proposed by the Codex Committee for Fats and Oils. This is the third and last scientific opinion of the EFSA Panel on Contaminants in the Food Chain (CONTAM Panel on this topic, in which sixteen of these substances or groups of substances have been evaluated. The CONTAM Panel concluded that sodium silicate (water glass solution, iso-octanol, iso-nonanol, iso-decanol, 1,3-propanediol, isobutyl acetate, sec-butyl acetate, tert-butyl acetate, n-butyl acetate, propylene tetramer, paraffin wax, candelilla wax, white mineral oils and glycerol would not be of health concern as previous cargoes. The CONTAM Panel concluded that carnauba wax was not acceptable as a previous cargo because of its insolubility in water and high melting point, which raise concerns regarding the efficiency of tank cleaning. There was insufficient information available on the composition of montan wax for the CONTAM Panel to conclude that it would be of no health concern when used as previous cargo and hence it does not meet the criteria for acceptability as previous cargo. The CONTAM Panel made several recommendations regarding the way in which the substances are described in the Annex to Commission Directive 96/3/EC, to correct inaccuracies and to better reflect current transport practices.

  2. Open Access and Civic Scientific Information Literacy

    Science.gov (United States)

    Zuccala, Alesia

    2010-01-01

    Introduction: We examine how residents and citizens of The Netherlands perceive open access to acquire preliminary insight into the role it might play in cultivating civic scientific literacy. Open access refers to scientific or scholarly research literature available on the Web to scholars and the general public in free online journals and…

  3. Preventing statistical errors in scientific journals.

    NARCIS (Netherlands)

    Nuijten, M.B.

    2016-01-01

    There is evidence for a high prevalence of statistical reporting errors in psychology and other scientific fields. These errors display a systematic preference for statistically significant results, distorting the scientific literature. There are several possible causes for this systematic error pre

  4. The philosophy of scientific experimentation: a review

    OpenAIRE

    Radder, H.

    2009-01-01

    Practicing and studying automated experimentation may benefit from philosophical reflection on experimental science in general. This paper reviews the relevant literature and discusses central issues in the philosophy of scientific experimentation. The first two sections present brief accounts of the rise of experimental science and of its philosophical study. The next sections discuss three central issues of scientific experimentation: the scientific and philosophical significance of interve...

  5. [Communication of scientific fraud].

    Science.gov (United States)

    Zeitoun, Jean-David; Rouquette, Sébastien

    2012-09-01

    There is for a scientific journal several levels of communication depending of the degree of suspicion or certainty of a case of error or fraud. The task is increasingly difficult for journal editors as disclosed cases of fraud are more common and scientific communication on this topic is growing. Biomedical fraud is fairly little reported by the mainstream press and causes of this low interest are not currently well understood. The difficulty of processing this type of news for journalists appears to be one possible reason. The potentially numerous and significant consequences of fraud on health professionals are poorly documented. Though it is likely to cause a feeling of distrust and create controversy, the impact of fraud on the general public is poorly studied and appears multifactorial. Copyright © 2012 Elsevier Masson SAS. All rights reserved.

  6. A Critique of the Theoretical and Empirical Literature of the Use of Diagrams, Graphs, and Other Visual Aids in the Learning of Scientific-Technical Content from Expository Texts and Instruction

    Science.gov (United States)

    Carifio, James; Perla, Rocco J.

    2009-01-01

    This article presents a critical review and analysis of key studies that have been done in science education and other areas on the effects and effectiveness of using diagrams, graphs, photographs, illustrations, and concept maps as "adjunct visual aids" in the learning of scientific-technical content. It also summarizes and reviews those studies…

  7. Scientific Software Component Technology

    Energy Technology Data Exchange (ETDEWEB)

    Kohn, S.; Dykman, N.; Kumfert, G.; Smolinski, B.

    2000-02-16

    We are developing new software component technology for high-performance parallel scientific computing to address issues of complexity, re-use, and interoperability for laboratory software. Component technology enables cross-project code re-use, reduces software development costs, and provides additional simulation capabilities for massively parallel laboratory application codes. The success of our approach will be measured by its impact on DOE mathematical and scientific software efforts. Thus, we are collaborating closely with library developers and application scientists in the Common Component Architecture forum, the Equation Solver Interface forum, and other DOE mathematical software groups to gather requirements, write and adopt a variety of design specifications, and develop demonstration projects to validate our approach. Numerical simulation is essential to the science mission at the laboratory. However, it is becoming increasingly difficult to manage the complexity of modern simulation software. Computational scientists develop complex, three-dimensional, massively parallel, full-physics simulations that require the integration of diverse software packages written by outside development teams. Currently, the integration of a new software package, such as a new linear solver library, can require several months of effort. Current industry component technologies such as CORBA, JavaBeans, and COM have all been used successfully in the business domain to reduce software development costs and increase software quality. However, these existing industry component infrastructures will not scale to support massively parallel applications in science and engineering. In particular, they do not address issues related to high-performance parallel computing on ASCI-class machines, such as fast in-process connections between components, language interoperability for scientific languages such as Fortran, parallel data redistribution between components, and massively

  8. Using Communication Technology to Facilitate Scientific Literacy: A Framework for Engaged Learning

    Science.gov (United States)

    VanBuskirk, Shireen Adele

    The purpose of this research project is to describe how existing communication technologies are used to foster scientific literacy for secondary students. This study develops a new framework as an analytic tool to categorize the activities of teachers and students involved in scientific literacy to describe what elements of scientific literacy are facilitated by such technologies. Four case studies are analyzed using the framework to describe the scientific literacy initiatives. Data collection at each site included interviews with the teacher, student focus groups, student surveys, and classroom observations. Qualitative analysis of the data provided insight into the learning activities and student experiences in the four cases. This study intentionally provides a platform for student voice. Very few previous empirical studies in the area of scientific literacy include the student experience. This represents a significant gap in the current literature on scientific literacy. An interpretation of scientific literacy that promotes student engagement, interaction, and initiative corresponds to a need to listen to students' perspectives on these experiences. Findings of the study indicated that the classroom activities depended on the teacher's philosophy regarding scientific literacy. Communication technology was ubiquitous; where the teacher did not initiate the use of social media in the classroom, the students did. The goal of supporting scientific literacy in students is an objective that extends beyond the boundaries of classroom walls, and it can be facilitated by technologies that seem both abundant and underutilized. Technology-enhanced pedagogy altered the classroom practices and resulted in more student participation and engagement.

  9. Perception of nursing students face clinical supervision: literature review

    OpenAIRE

    Certo, Ana; Galvão, Ana Maria; Louçano, Ana

    2015-01-01

    Currently, without theoretical clinical training is not possible for the nursing student adequately meet their clinical practices.In this regard, clinical supervision plays a key role monitoring and development of the same. However,so that the student can be supervised, requires evidence of nurse supervisor competence in this context. In contemporary literature, this issue has been much debated, as the target of numerous different scientific studies. Aim of the study was, under...

  10. Botulinum neurotoxin type A injection of the pelvic floor muscle in pain due to spasticity: a review of the current literature.

    Science.gov (United States)

    Bhide, Alka A; Puccini, Federica; Khullar, Vik; Elneil, Suzy; Digesu, G Alessandro

    2013-09-01

    The role of muscle spasm is not a new concept in the genesis of pain. Botulinum neurotoxin type A (BoNTA) has been successfully employed in a variety of muscular and inflammatory conditions. The aim of our study was to review the published literature on the role of BoNTA injection of the pelvic floor muscle in the management of women with chronic pelvic pain (CPP). A systematic search of the literature published up to June 2012 on the use of BoNTA in the treatment of female pelvic floor muscle spasm was carried out using relevant search terms in MEDLINE and EMBASE databases. The results were limited to full-text English language articles. Relevant trials as well as relevant reviews were selected and analyzed by two independent reviewers. Five studies (2 case reports, 1 prospective pilot study, 1 retrospective study and 1 randomised double-blind placebo controlled study) were included in this systematic review. Overall, BoNTA has shown to be beneficial in relieving CPP related to pelvic floor spasm. The role of BoNTA as a treatment of CPP has been recognized for more than 10 years. Although data are still scarce preliminary results are encouraging. BoNTA is an attractive option for refractory CPP related to pelvic floor muscle spasm, but further studies using validated and reproducible outcome measures are needed, to establish its effectiveness, safeness, technique, optimal dosage, and duration of symptom relief.

  11. [Factors Associated with Suicide in Adolescents and Young People Self-Identified as Lesbian, Gay, and Bisexual: Current State of the Literature].

    Science.gov (United States)

    Pineda Roa, Carlos Alejandro

    2013-12-01

    A framework within sexual and reproductive health is presented to understand the mental health issues of the population of lesbian, gay and bisexual (LGB) adolescents and young people. Different ways of understanding the nature of internalized homophobia were developed. On the other hand, in suicidology studies it is understood that the risk of suicide consists of the steps of ideation, planning and attempted suicide, and that there is an increased risk of suicide in the LGB population. Numerous factors have been associated with suicide risk in this population, one of the main internalized homophobia and other mental health problems. By means of a literature review, to establish the possible relationship between internalized homophobia and ideation and attempted suicide in the LGB population, as well as to identify the mental health problems associated to suicide risk in sexually diverse communities. Articles in English and Spanish, mainly within the last five years, were reviewed. They included articles in peer reviewed journals, and databases, such as Google Scholar, Redalyc, Byreme, Ovid, Science Direct, Taylor and Francis, MEDLINE, Scopus, PsycINFO, and Ebsco. It was found in the available literature that internalized homophobia is associated with suicide ideation and attempts in adults. A state of science of the major mental health problems associated with suicide risk in young LGB people reported contradictory findings. While some studies showed an association between depression, anxiety and distress and suicidal ideation and attempts, in others, the data do not allow such a conclusion. The theoretical framework presents the most important conceptualizations of suicide risk and emphasizes the social type. It identifies issues of suicide prevention, protective factors that contribute towards this, as well as elements of psychotherapy for LGB consultants. It concludes and discusses the importance of studying the sexually diverse as regards determining factors

  12. Teaching Literature to Adolescents

    Science.gov (United States)

    Beach, Richard W.; Appleman, Deborah; Hynds, Susan; Wilhelm, Jeffrey

    2006-01-01

    This text for pre-service and in-service English education courses presents current methods of teaching literature to middle and high school students. The methods are based on social constructivist/socio-cultural theories of literacy learning, and incorporate research on literary response conducted by the authors. "Teaching Literature to…

  13. Scientific ballooning in Brazil

    Science.gov (United States)

    Corrêa, R.; Rinke, E.; Fernandes, J. O.; Villela, T.

    We present an overview of the scientific ballooning activities that took place in Brazil over the past 30 years as well as the current ongoing efforts in the area. We also briefly describe the balloon launching facility that exists at the Instituto Nacional de Pesquisas Espaciais (National Institute for Space Research) — INPE. Up to now, over 100 scientific balloon experiments, related to Astrophysics, Aeronomy, and Geophysics were launched from Brazil taking advantage of the country's continental dimensions, a well-defined rain season, and a low population density, which offer excellent conditions for scientific ballooning activities. Balloons with volumes up to 500,000 cubic meters can be launched from INPE's balloon launching base (latitude S 22° 4' 2″; longitude W 044° 58' 41″). The availability of good roads and several inland airports in Brazil provides the necessary structure for safe payload retrieval and its rapid return to the balloon base. There are several airports throughout Brazil that can also be used as balloon launching bases, mainly in the country's Eastern region. Overflights of more than 1,000 kilometers are possible and easily attained. Balloon flights ranging from a few hours to long duration flights can be safely verified. The constant climate monitoring through the use of weather satellites information received at INPE provides the necessary data to determine the necessary conditions for a long duration flight. INPE's Center for Weather Forecast and Climate Studies (CPTEC) provides the necessary weather forecast support for launch and payload retrieval.

  14. Scientific Coolections: Informational - Navigational Portal for Scientific Publications Access.

    Science.gov (United States)

    Bogatencov, Petru; Kozlenco, Ludmila; Ginculova, Silvia; Keradi, Natalia

    At present there is the tendency of uniting efforts of scientific establishments and libraries for using information - communication medium with the purpose of information support of research and pedagogical activity in Moldova. The efficient access to the scientific and technical literature and, first of all, to the new publications, is necessary practically for all scientists and experts irrespective of a field of knowledge, in which they work. Research institutions, knowing how to receive access to the electron information and to use it intellectually, realize that it effects positively the quality and outcomes of the research process. It is obvious, that to ensure maximum utilization of the new information stream by habitual methods is impossible. New non-traditional approaches are necessary for the increase of the level of information provision of scientists and experts. Creation of electron libraries, realizing qualitatively other level of production, storage, organization and distribution of various information is the most effective way to gin this object. The access to the electron versions of scientific journals allows to reduce the acuteness of shortage of scientific literature, the electron information becomes accessible before the publication of paper version of a journal, and taking into account the delivery time of foreign issues into Moldova, this outstripping can reach several months.

  15. 大洋性柔鱼类资源开发现状及可持续利用的科学问题%Current exploitation and some scientific issues in the sustainable utilization of Ommastrephidae

    Institute of Scientific and Technical Information of China (English)

    陈新军; 陆化杰; 刘必林; 田思泉

    2012-01-01

    大洋性柔鱼类是重要的渔业资源,商业性开发的种类主要有太平洋褶柔鱼、柔鱼、阿根廷滑柔鱼、茎柔鱼和双柔鱼等。据统计,1992-2010年柔鱼类产量占世界头足类的比重稳定在51.15%~62.19%,平均达到55.40%。对重要柔鱼种类的资源现状及开发状况进行系统分析,根据大洋性柔鱼类生命周期短、生长快等特点,提出了4项需研究的问题,即:(1)全面了解大洋性柔鱼类的生态地位和作用;(2)全面掌握环境包括全球气候变化对大洋性柔鱼类资源补充量的影响;(3)深入研究大洋性柔鱼类短生命周期资源评估模式;(4)发展基于生态系统的大洋性柔鱼类资源管理方法。%The oceanic Ommastrephidae is an important cephalopod resource.The main species which have been exploited at the large-scale commercial development included Todarodes pacificus,Illex argentinus,Dosidicus gigas,Nototodarus sloani and Symplectoteuthis oualaniensis.According to the data statistics during 1992 to 2010,the Ommastrephidae production accounted for 51.15%-62.19% of cephalopods in the world,with an average of 55.40%.In this paper,the current exploitation and resources conditions of Todarodes pacificus,Illex argentinus,Dosidicus gigas and other squids are described in details.Meanwhile,according to the biological characteristics of short life cycle and fast growth,four major scientific issues which are to be resolved have been put forward.The four scientific issues are:(1) a completely comprehensive understanding of the ecological status and role of Ommastrephidae;(2) fully mastering the effect of environment including global climate change on the recruitment of Ommastrephidae;(3) further study of assessment model for Ommastrephidae based on the short life cycle;and(4) developing the ecosystem-based resource management approaches for Ommastrephidae.

  16. Secondhand Smoke Is an Important Modifiable Risk Factor in Sickle Cell Disease: A Review of the Current Literature and Areas for Future Research

    Directory of Open Access Journals (Sweden)

    S. Christy Sadreameli

    2016-11-01

    Full Text Available Sickle cell disease (SCD is an autosomal recessive hemoglobinopathy that causes significant morbidity and mortality related to chronic hemolytic anemia, vaso-occlusion, and resultant end-organ damage. Tobacco smoke exposure (TSE through secondhand smoke exposure in people with SCD of all ages and through primary smoking in adolescents and adults is associated with significantly increased morbidity, with increased rates of emergency department visits and hospitalizations for painful vaso-occlusive crises and acute chest syndrome (ACS. Secondhand smoke is also associated with pulmonary function abnormalities in children with SCD who are already at risk for pulmonary function abnormalities on the basis of SCD. TSE is emerging as one of the few modifiable risk factors of SCD. This review discusses the current state of the evidence with respect to TSE and SCD morbidity, discusses potential mechanisms, and highlights current gaps in the evidence and future research directions.

  17. Olfactory neuroblastoma (esthesioneuroblastoma): towards minimally invasive surgery and multi-modality treatment strategies - an updated critical review of the current literature.

    Science.gov (United States)

    Papacharalampous, G X; Vlastarakos, P V; Chrysovergis, A; Saravakos, P K; Kotsis, G P; Davilis, D I

    2013-01-01

    Olfactory neuroblastoma (esthesioneuroblastoma) was first described by Berger and Luc in 1924. It is considered to be an uncommon malignancy of the nasal cavity. The tumor arises from the specialized sensory epithelial olfactory cells, normally situated at the upper part of the nasal cavity, including the superior nasal concha, the roof of the nose and the cribriform plate. The imaging modalities of choice are computed tomography (CT) and magnetic resonance imaging (MRI). Combination of surgery and radiotherapy (either conventional radiotherapy or stereotactic radiosurgery), with or without chemotherapy is considered to be the standard of care for primary site disease by the majority of researchers. Combined transfacial and neurosurgical conventional approaches are also adopted in many reported cases, mainly due to the endocranial extension and the close anatomic relationship of esthesioneuroblastomas with the ethmoid roof and cribriform plate. Recent literature supports that endoscopic resection correlates with similar oncologic control rates compared with conventional open surgery, provided that basic oncologic surgical principles with clearance of margins and intradural dissection (when required) are completely maintained.

  18. Does the initiation of urate-lowering treatment during an acute gout attack prolong the current episode and precipitate recurrent attacks: a systematic literature review.

    Science.gov (United States)

    Eminaga, Fatma; La-Crette, Jonathan; Jones, Adrian; Abhishek, A

    2016-12-01

    The aim of this study was to systematically review the literature on effect of initiating urate-lowering treatment (ULT) during an acute attack of gout on duration of index attack and persistence on ULT. OVID (Medline), EMBASE and AMED were searched to identify randomized controlled trials (RCTs) of ULT initiation during acute gout attack published in English language. Two reviewers appraised the study quality and extracted data independently. Standardized mean difference (SMD) and relative risk (RR) were used to pool continuous and categorical data. Meta-analysis was carried out using STATA version 14. A total of 537 studies were selected. A total of 487 titles and abstracts were reviewed after removing duplicates. Three RCTs were identified. There was evidence from two high-quality studies that early initiation of allopurinol did not increase pain severity at days 10-15 [SMDpooled (95 % CI) 0.18 (-0.58, 0.93)]. Data from three studies suggested that initiation of ULT during an acute attack of gout did not associate with dropouts [RRpooled (95 % CI) 1.16 (0.58, 2.31)]. There is moderate-quality evidence that the initiation of ULT during an acute attack of gout does not increase pain severity and risk of ULT discontinuation. Larger studies are required to confirm these findings so that patients with acute gout can be initiated on ULT with confidence.

  19. [CPM--Continuous Passive Motion: treatment of injured or operated knee-joints using passive movement. A meta-analysis of current literature].

    Science.gov (United States)

    Kirschner, P

    2004-04-01

    There is still a controversial discussion in literature about the use of motor driven splints in knee surgery--as the principle of continuous passive motion, CPM. For this reason it seemed useful for an evaluation to look through the papers which were published since 1990. It was obvious, that negative results were published often before this year, but this papers are still quoted standard works. In medical data bases subito-doc.de, medscape.com, medica.de and zbmed.de 230 papers were found by search CPM, continuous passive motion and arthromot. Coincidentally there was a search for authors who were already quoted in other papers. 36 papers concerning CPM after knee surgery were utilized. The role of CPM regarding the range of motion, swelling, duration of hospital stay, use of analgesics, costs, postoperative manipulations, wound healing and thrombo embolic complications was evaluated. Although the results of this partial retrospective, partial prospective, sometimes randomized or double blinded studies are in contradiction, there can only be found a trend to better results. New clinical studies for evidence based guidelines in the handling of continuous passive motion after knee surgery are necessary.

  20. Scientific journal cancellations

    CERN Multimedia

    The Library

    2001-01-01

    Earlier this year the Scientific Information Policy Board (SIPB) requested the Library and the Working Group for Acquisitions to revise the current printed journal collection in order to cancel those titles that are less required. Savings could then be used for the development of other collections and particularly electronic resources needed to support CERN current research activities. A list of proposed cancellations was drawn and posted on the Library web pages: http://library.cern.ch/library_general/cancel.html The SIPB invites every one to check if any of the titles are of importance to their work, in which case you are invited to inform the Library before the 25th of September by sending an e-mail to: eliane.chaney@cern.ch Titles not reconsidered by the users will be cancelled by the end of the year. Thank you, The Library

  1. Real-Time Three-Dimensional Echocardiography: Characterization of Cardiac Anatomy and Function—Current Clinical Applications and Literature Review Update

    Science.gov (United States)

    Velasco, Omar; Beckett, Morgan Q.; James, Aaron W.; Loehr, Megan N.; Lewis, Taylor G.; Hassan, Tahmin; Janardhanan, Rajesh

    2017-01-01

    Abstract Our review of real-time three-dimensional echocardiography (RT3DE) discusses the diagnostic utility of RT3DE and provides a comparison with two-dimensional echocardiography (2DE) in clinical cardiology. A Pubmed literature search on RT3DE was performed using the following key words: transthoracic, two-dimensional, three-dimensional, real-time, and left ventricular (LV) function. Articles included perspective clinical studies and meta-analyses in the English language, and focused on the role of RT3DE in human subjects. Application of RT3DE includes analysis of the pericardium, right ventricular (RV) and LV cavities, wall motion, valvular disease, great vessels, congenital anomalies, and traumatic injury, such as myocardial contusion. RT3DE, through a transthoracic echocardiography (TTE), allows for increasingly accurate volume and valve motion assessment, estimated LV ejection fraction, and volume measurements. Chamber motion and LV mass approximation have been more accurately evaluated by RT3DE by improved inclusion of the third dimension and quantification of volumetric movement. Moreover, RT3DE was shown to have no statistical significance when comparing the ejection fractions of RT3DE to cardiac magnetic resonance (CMR). Analysis of RT3DE data sets of the LV endocardial exterior allows for the volume to be directly quantified for specific phases of the cardiac cycle, ranging from end systole to end diastole, eliminating error from wall motion abnormalities and asymmetrical left ventricles. RT3DE through TTE measures cardiac function with superior diagnostic accuracy in predicting LV mass, systolic function, along with LV and RV volume when compared with 2DE with comparable results to CMR.

  2. Diagnosing Lung Cancers through Examination of Micro-RNA Biomarkers in Blood, Plasma, Serum and Sputum: A Review and Summary of Current Literature

    Directory of Open Access Journals (Sweden)

    Jennifer Gyoba

    2016-04-01

    Full Text Available Lung cancer is the leading cause of cancer related morbidity and mortality worldwide. Currently, the vast majority of lung cancers are diagnosed at a late stage, when patients become symptomatic leading to dismal, less than 15% five-year survival rates. Evidence has demonstrated that screening computed tomography scans can be used to detect lung cancer, but these scans have high false positive rates. Therefore, there is a continued need for the development of minimally-invasive methods to screen the high risk population and diagnose lung cancer at an earlier, curable stage. One such promising area is the use micro-RNAs. These are short, non-coding RNA molecules that have been shown in previous research to be dysregulated in cancers. This review will focus on the potential use of miRNA levels in various biological fluids (whole blood, plasma, serum, and sputum and demonstrate their potential utility as screening and diagnostic biomarkers for lung cancer. Current research will be analyzed and compared, and future directions in establishing the use of miRNAs for detecting lung cancer will be discussed.

  3. Diagnosing Lung Cancers through Examination of Micro-RNA Biomarkers in Blood, Plasma, Serum and Sputum: A Review and Summary of Current Literature.

    Science.gov (United States)

    Gyoba, Jennifer; Shan, Shubham; Roa, Wilson; Bédard, Eric L R

    2016-04-01

    Lung cancer is the leading cause of cancer related morbidity and mortality worldwide. Currently, the vast majority of lung cancers are diagnosed at a late stage, when patients become symptomatic leading to dismal, less than 15% five-year survival rates. Evidence has demonstrated that screening computed tomography scans can be used to detect lung cancer, but these scans have high false positive rates. Therefore, there is a continued need for the development of minimally-invasive methods to screen the high risk population and diagnose lung cancer at an earlier, curable stage. One such promising area is the use micro-RNAs. These are short, non-coding RNA molecules that have been shown in previous research to be dysregulated in cancers. This review will focus on the potential use of miRNA levels in various biological fluids (whole blood, plasma, serum, and sputum) and demonstrate their potential utility as screening and diagnostic biomarkers for lung cancer. Current research will be analyzed and compared, and future directions in establishing the use of miRNAs for detecting lung cancer will be discussed.

  4. Passages on Brazilian scientific cinema.

    Science.gov (United States)

    de Almeida, Jane; da Silva, Cicero Inacio; Suppia, Alfredo; Stalbaum, Brett

    2017-07-01

    The article examines the conditions of production and recognition of scientific cinema in Brazil by comparing three distinct moments and contexts: the first moment takes place in the nineteenth century, and it is related to the contribution of a Brazilian astronomer otherwise little known to Brazilian film scholars, the second addresses Benedito Junqueira Duarte's voluminous mid-twentieth-century filmography, and the third moment documents recent scientific film experiences within ultra high resolution movies transmitted over photonic networks. Future trajectories for aesthetic concerns and practical issues such as the archiving of ultra high definition cinema are usefully informed by these histories of scientific cinema, even as a current generation of multidisciplinary teams including scientists, filmmakers, computer scientists, and network engineers reinvent, rediscover, and necessarily expand the scientific cinema toward concerns of real time collaboration and teaching.

  5. Methods for Obtaining Free Full-text of Scientific Papers in the Literature Search%科学研究中免费科技论文获取方法探讨

    Institute of Scientific and Technical Information of China (English)

    陈平; 李道西

    2011-01-01

    Six methods for obtaining free full-text of scientific papers are introduced,including effective use of public search engines;full use of academic search engines;the collection of common resource sites providing free scientific papers;the concern about the important professional journals' home webs,the authors' academic blogs or the website of the relevant academic research institutions;to friends or forums for help;direct request to the authors and so on.%介绍了6种获取免费科技论文全文的方法,分别是有效利用大众搜索引擎;充分利用学术搜索引擎;收集常用的免费科技论文资源网站;关注本专业重要期刊主页、作者学术博客或相关科研机构网站;向朋友或论坛求助;直接向作者索取等。

  6. Scientific and Technical Demand and Current Situations of Cassava Biomass Energy Industry in China%我国木薯生物质能源产业发展现状与科技需求

    Institute of Scientific and Technical Information of China (English)

    韦昌联; 卢柳忠; 黎贞崇

    2012-01-01

    Based on the analysis of current situations of cassava biomass energy industry in China and the relative advances in science and technology,the major existed problems in this industry were put forward.Furthermore,scientific and technical demands for further development of cassava biomass energy industry were discussed covering the following aspects:strengthening the research on the culture and the matching cultivation technology of new varieties of high-yield high-starch cassava,launching the development of cassava full-process automated manufacturing equipments,strengthening the research on cassava comprehensive utilization and the development of new cassava products,and strengthening the research on the recycle use of cassava waste and the relative techniques.%在分析我国木薯生物质能源产业现状和科技发展进展的基础上,指出了当前木薯生物质能源产业科技发展存在的主要问题。提出了下一步产业发展的科技需求,重点是加强高产高粉木薯新品种培育和配套栽培技术研究,开展木薯全程机械化系列产品的研发,加强木薯综合利用技术和产品攻关及木薯废弃物的资源化利用技术的研发力度。

  7. Neonicotinoids in the Canadian aquatic environment: a literature review on current use products with a focus on fate, exposure, and biological effects.

    Science.gov (United States)

    Anderson, J C; Dubetz, C; Palace, V P

    2015-02-01

    Developed to replace organophosphate and carbamate insecticides, neonicotinoids are structurally similar to nicotine. The three main neonicotinoid insecticides, imidacloprid, clothianidin, and thiamethoxam, are being re-evaluated by Health Canada's Pest Management Regulatory Agency (PMRA). An important aspect of the re-evaluation is the potential for effects in non-target organisms, including aquatic organisms. Leaching into surface waters is one of the major concerns surrounding extensive use of neonicotinoids, especially in close proximity to water bodies. The PMRA has classified IMI as 'persistent' with a 'high' leaching potential. Globally, neonicotinoids have been detected in a variety of water bodies, typically at concentrations in the low μg/L range. While IMI has been included in some monitoring exercises, there are currently very few published data for the presence of CLO and THM in Canadian water bodies. The majority of neonicotinoid toxicity studies have been conducted with IMI due to its longer presence on the market and high prevalence of use. Aquatic insects are particularly vulnerable to neonicotinoids and chronic toxicity has been observed at concentrations of IMI below 1 μg/L. Acute toxicity has been reported at concentrations below 20 μg/L for the most sensitive species, including Hyalella azteca, ostracods, and Chironomus riparius. Fish, algae, amphibians, and molluscs are relatively insensitive to IMI. However, the biological effects of THM and CLO have not been as well explored. The Canadian interim water quality guideline for IMI is 0.23 μg/L, but there is currently insufficient use, fate, and toxicological information available to establish guidelines for CLO and THM. Based on concentrations of neonicotinoids reported in surface waters in Canada and globally, there is potential for aquatic invertebrates to be negatively impacted by neonicotinoids. Therefore, it is necessary to address knowledge gaps to inform decisions around guidelines

  8. Scientific substantiation of functional food health claims in China.

    Science.gov (United States)

    Yang, Yuexin

    2008-06-01

    This article provides an overview of the procedures involved in scientific substantiation of functional food health claims in China. The definition of a functional food is discussed, in addition to the factors that led to its modification in 2005. The framework of administration includes the regulation of functional foods, steps involved in submission of dossiers, the safety control system for raw materials and products, and technical procedures for testing and evaluation. Scientific evidence required for a claim includes evidence from product tests in addition to evidence resulting from complete scientific literature searches relative to the food material or component in question. Currently, the 4 main rules for functional food assessment in China include 1) functional assessment procedures; 2) standard toxicological assessment; 3) regulations on nutrient supplements; and 4) standard analytical methods for functional components. The current situation for functional foods in China is analyzed, including a discussion of the distribution of the 27 currently allowed functional food health claims. The effectiveness of functional foods and health claims for improving health relies largely on the motivation and education of the public to be able to make good choices.

  9. Plate tectonics: Scientific revolution or scientific program?

    Science.gov (United States)

    Mareschal, Jean-Claude

    In The Structure of Scientific Revolutions, Thomas S. Kuhn suggested that science progresses discontinuously: As a scientific theory becomes obsolete, a period of crisis results, at the end of which the old theory is overthrown and replaced by a new, sounder, more complete theory [Kuhn, 1962]. After the scientific community has accepted the new [paradigm,] it undertakes only routine research until a new crisis occurs, usually as a result of an anomalous experiment that accidentally happens to be critical.

  10. 陕西省土地利用/覆盖变化以及驱动机制分析——基于遥感信息与文献集成研究%Analysis of Land Use and Coverage Change (LUCC) and Its Driving Mechanisms in Shaanxi Province: Integrating Remotely Sensed Information and the Scientific Literature

    Institute of Scientific and Technical Information of China (English)

    匡文慧

    2011-01-01

    地理结论的可靠性一直以来是地理学家关注的焦点问题。本研究建立了基于高分辨率遥感信息获取的土地利用/覆盖变化数据和参考文献集成与再分析方法。以陕西省为例,通过土地利用/覆盖变化动态数据分析结果与研究区40篇参考文献分析结果进行相互验证,提炼土地利用/覆盖变化以及驱动机制的知识规律。结论表明,基于土地利用/覆盖变化数据的分析结果与参考文献集成分析的结果基本一致。1990年-2005年陕西省耕地总面积减少,耕地呈先增加后减少的趋势;林地和草地面积逐渐增加;建设用地快速增长。人口、经济、政策与城市化是该省土地利用%Geographical conclusion reliability has been an important topic for geographers. This study proposed a new technique to integrate data on land use/land cover change, remotely sensed information, as well as the scientific literature. First, the project team constructed the global land information platform (GLIP), including the global land use/land cover the electrical scientific literature base and multi-scale LUCC data. Global Land Use Scientific Literature Base (GLUSLB) has more than 5000 references on land use and land cover. We reclassified the scientific literature into 6 classes, including application, technology, methodology, review, model, and data. Furthermore, the scientific literature on application and data with definite location is located in the specific geo-ecological region. Second, compared with land use and land cover change areas from between LUCC data and 40 references, spatial and temporal characteristics and their driving mechanisms were analyzed. Results indicate that the conclusions are generally consistent with both of them, especially the land use change characteristics from different administrative systems. From 1990 to 2005, the total area of cultivated land in Shaanxi Province generally decreased, but increased during

  11. Scientific aesthetics: three steps forward.

    Science.gov (United States)

    Chatterjee, Anjan

    2014-11-01

    Leder and Nadal (2014, this issue) examine the current state of scientific aesthetics through the lens of a prescient psychological model proposed 10 years ago. These retrospective points to several future directions of which I touch on three: the nature of aesthetic emotions, the time course of emotions in aesthetic episodes, and the relationship of art and evolution.

  12. Building Bridges through Scientific Conferences

    DEFF Research Database (Denmark)

    Zierath, Juleen R

    2016-01-01

    Getting together to exchange ideas, forge collaborations, and disseminate knowledge is a long-standing tradition of scientific communities. How conferences are serving the community, what their current challenges are, and what is in store for the future of conferences are the topics covered...

  13. Predictive factors for recurrence of differentiated thyroid cancer in patients under 21 years of age and a meta-analysis of the current literature.

    Science.gov (United States)

    Qu, Ning; Zhang, Ling; Lu, Zhong-Wu; Ji, Qing-Hai; Yang, Shu-Wen; Wei, Wen-Jun; Zhang, Yan

    2016-06-01

    The influence of predictors for recurrence in relation to recurrence-free survival was analyzed retrospectively in differentiated thyroid cancer (DTC) patients under 21 years of age who underwent primary surgical treatment and who had a pathological diagnosis of DTC between 1983 and 2012 at Fudan University Cancer Hospital. Recurrences were retrospectively analyzed using a Cox regression model for the hazard ratio (HR) according to the clinicopathological features. A meta-analysis was performed with respect to the potential predictors for recurrence from current related studies. In the present study, there were 146 young patients aged from 7 to 20 years, with a female/male ratio of 2.65/1. Female gender was the only factor significantly associated with recurrence according to univariate (HR = 2.812, P = 0.037) and multivariate (HR = 4.107, P = 0.024) Cox regression analyses. Meta-analyses revealed that multifocality (HR = 1.91, P < 0.05) and presentation at diagnosis (HR = 1.39, P < 0.05) were highly associated with recurrence in young DTC patients. However, female gender and other factors, such as age (≤10 vs. 11-20 years), PTC (PTC vs. FTC), extrathyroidal extension, lymph node metastasis, total thyroidectomy (total vs. less than total), radioiodine therapy, and radiation history, were not associated with recurrence in young DTC patients. In conclusion, multifocality and presentation at diagnosis are strong predictive factors of recurrence in relation to recurrence-free survival. We recommend studies with larger sample sizes and longer follow-up to verify the influence of predictors for disease recurrence in young patients.

  14. CONTEMPORARYFOREIGN LITERATURE

    Institute of Scientific and Technical Information of China (English)

    Lawrence Bue; Marshall Brown; Alfred Hornung; James Phelan; Elizabeth Schultz; David Attwell

    2011-01-01

    Contemporary Foreign Literature ( CFL,CN32-1087/I,ISSN 1001-1757 ),originated in 1980,is a journal of articles and reviews on contemporary literature except that of China.Peer-reviewed and published quarterly,in January,April,July and October,by the Institute of Foreign Literature,Nanjing University and the Yilin Press,CFL is indexed in the Chinese Social Sciences Citation Index (CSSCI).

  15. Socio-Scientific Decision Making in the Science Classroom

    Science.gov (United States)

    Siribunnam, Siripun; Nuangchalerm, Prasart; Jansawang, Natchanok

    2014-01-01

    The learning ability of students in science is improved by socio-scientific decision-making, an important activity that improves a student's scientific literacy, conceptual understanding, scientific inquiry, attitudes, and social values. The socio-scientific issues must be discussed during science classroom activities in the current state of 21st…

  16. Bibliometric Analysis of The Sport Core Periodicals Scientific Literature of Tennis Research in Recent Ten Years%近10年体育类核心期刊网球科研文献计量学研究

    Institute of Scientific and Technical Information of China (English)

    吕煜寰

    2016-01-01

    In this paper,using literature data method,mathematical statistics and logic analysis method,the CSSCI nearly 10 years (2006-2015),Chinese sports core periodicals in our country about tennis research literature as the research object,with range of study,journal of contribution rate,the author title,such as content analysis.Through objective data statistical analysis and data collected in nearly 10 years of domestic research Angle of view,the main academic point of view about the tennis project, value orientation,and the future research trend,further improve the research level of tennis sport in our country, promote the development of tennis in our country and popularity.%该文运用文献资料法、数理统计法、逻辑分析法,对近10年(2006—2015)我国中文类体育核心期刊有关网球科研文献进行文献计量分析,以研究领域、学刊贡献率、作者职称等内容进行统计分析,旨在通过客观的数据统计分析来探析近10年国内关于网球项目的研究视角、主要学术观点、价值取向、以及未来研究趋势等,进一步提高我国网球运动的科研水平,推动网球在我国的发展与普及。

  17. Medizinhistorische Literatur [Medical history literature

    Directory of Open Access Journals (Sweden)

    Bauer, Bruno

    2012-09-01

    Full Text Available [english] The focus of the current issue 1-2/2012 of GMS Medizin – Bibliothek – Information is on medical history literature. In six articles special collections and recent projects of medical history libraries in Berlin, Hamburg, Heidelberg, Leipzig, Vienna and Zurich are presented. The authors in this issue are Melanie Scholz & Vera Seehausen (From Augusta to Klingsor, from Luise to Benjamin – past, present and future of the library of the Institute of the History of Medicine in Berlin, Alexandra Veith (Library of the Institute for History of Medicine and Ethics of Medicine, Heidelberg, Melanie Kintzel, Meike Knittel & Tanja Krutky (Historic collections of the Medical Library of the University of the University Medical Center Hamburg-Eppendorf and their deacidification, Dagmar Geithner (Library of the Karl Sudhoff Institute for the History of Medicine and Science, Leipzig – a Historical Review, Harald Albrecht, Bruno Bauer & Walter Mentzel (The Josephinian Library and the medical-historic stock of the University Library of the Medical University of Vienna and Monika Huber & Ursula Reis (Library of the Institute and Museum of the History of Medicine Zurich.[german] Schwerpunktthema der aktuellen Ausgabe 1-2/2012von GMS Medizin – Bibliothek – Information ist medizinhistorische Literatur. In sechs Beiträgen werden Bestände und aktuelle Projekte medizinhistorischer Bibliotheken in Berlin, Hamburg, Heidelberg, Leipzig, Wien und Zürich vorgestellt. Verfasst wurden die Beiträge der Schwerpunktausgabe von Melanie Scholz & Vera Seehausen (Von August zu Klingsor, von Luise zu Benjamin – Vergangenheit, Gegenwart und Zukunft der Bibliothek des Instituts für Geschichte der Medizin in Berlin, Melanie Kintzel, Meike Knittel & Tanja Krutky (Medizinhistorische Buchbestände am Universitätsklinikum Hamburg-Eppendorf und ihre Entsäuerung, Ara Veith (Bibliothek des Instituts für Geschichte und Ethik der Medizin in Heidelberg, Dagmar Geithner

  18. Attaining Performance with Building Information Modelling: A systematic literature review of product and process modelling in AEC

    NARCIS (Netherlands)

    Papadonikolaki, E.; Koutamanis, A.; Wamelink, J.W.F.

    2013-01-01

    The paper presents the findings of a systematic literature review of approximately 200 scientific sources. It is designed with the aim to identify the current benefits and factors of high performance in Architecture, Engineering, Construction (AEC) since the introduction of Building Information

  19. Scientific Utopia: An agenda for improving scientific communication (Invited)

    Science.gov (United States)

    Nosek, B.

    2013-12-01

    The scientist's primary incentive is publication. In the present culture, open practices do not increase chances of publication, and they often require additional work. Practicing the abstract scientific values of openness and reproducibility thus requires behaviors in addition to those relevant for the primary, concrete rewards. When in conflict, concrete rewards are likely to dominate over abstract ones. As a consequence, the reward structure for scientists does not encourage openness and reproducibility. This can be changed by nudging incentives to align scientific practices with scientific values. Science will benefit by creating and connecting technologies that nudge incentives while supporting and improving the scientific workflow. For example, it should be as easy to search the research literature for my topic as it is to search the Internet to find hilarious videos of cats falling off of furniture. I will introduce the Center for Open Science (http://centerforopenscience.org/) and efforts to improve openness and reproducibility such as http://openscienceframework.org/. There will be no cats.

  20. Research on the current situation of sports scientific literature of sports for the disabled in China%我国残疾人竞技体育科研文献现状研究

    Institute of Scientific and Technical Information of China (English)

    王辉

    2014-01-01

    科研是我国残疾人竞技体育发展的重要助力,其科研文献是主要表现方式.中国知网相关残疾人竞技体育文献显示:文献年度数量分布与奥运周期和成绩较为契合.体育专业性文献较少,高校相关教育及研究水平较为滞后.研究方向着重于现状、报道等的研究,且研究深度不足;研究缺乏残冬奥会的研究.