WorldWideScience

Sample records for current results include

  1. Applications and limitations of thermobarometry in migmatites and granulites using as an example rocks of the Araçuaí Orogen in southern Bahia, including a discussion on the tectonic meaning of the current results

    Directory of Open Access Journals (Sweden)

    Renato Moraes

    Full Text Available In southern Bahia, there are outcrops of migmatites and granulites in the Jequitinhonha Complex, which is part of the northern portion of the Araçuaí Orogen. Migmatites (garnet-cordierite diatexite dominate the metamorphic rocks and host lenses and layers of felsic garnet granulite. The conditions of temperature and pressure of metamorphism were calculated using conventional thermobarometry and the software THERMOCALC. Values around 850 °C and 7 kbar were obtained with THERMOCALC. The calculations for the garnet-cordierite diatexite were made considering aH2O equal to 1, but the best results of calculations for the granulites are obtained with aH2O values of 0.3. Pressure values obtained with GAPES resulted in consistent values with THERMOCALC, but the pair garnet-orthopyroxene always produces low values for temperature and high ones for pressure. The results are consistent with the presence of the pair garnet and cordierite in diatexite and orthopyroxene in felsic granulite. From the tectonic point of view, the setting in which metamorphism of these rocks occurred requires high heat flow with a thermal anomaly in mid continental crust, as indicated by values of 7 kbar. Recent studies have favored the closure of a back-arc basin for this tectonic setting, but it does not solve the problem that the time span between metamorphic peak and the end of granite intrusions, involving large bodies of charnockite, is more than 80 million years. The model of tectonic switching is suggested here as it can explain the maintenance of high temperatures for a more extended interval of time.

  2. Joint voltages resulting from lightning currents.

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, William Arthur; Warne, Larry Kevin; Merewether, Kimball O.; Chen, Kenneth C.

    2007-03-01

    Simple formulas are given for the interior voltages appearing across bolted joints from exterior lightning currents. External slot and bolt inductances as well as internal slot and bolt diffusion effects are included. Both linear and ferromagnetic wall materials are considered. A useful simplification of the slot current distribution into linear stripline and cylindrical parts (near the bolts) allows the nonlinear voltages to be estimated in closed form.

  3. Chemical composition of planetary nebulae : Including ISO results

    NARCIS (Netherlands)

    Pottasch, [No Value; Beintema, DA; Salas, JB; Feibelman, WA; Henney, WJ; Franco, J; Martos, M; Pena, M

    2002-01-01

    The method of determining abundances using Infrared Space Observatory spectra is discussed. The results for seven planetary nebula are given. Using these data, a preliminary discussion of their evolution is given.

  4. Current results and trends in platform switching

    Directory of Open Access Journals (Sweden)

    Hadi Salimi

    2011-01-01

    Full Text Available The platform switching (PLS concept was introduced in the literature in 2005. The biological benefits and clinical effectiveness of the PLS technique have been established by several studies. In this article different aspects of PLS concept are discussed. Crestal bone loss, biologic width, and stress distribution in this concept are comprehensively reviewed. In this article the relative published articles from 1990 to 2011 have been evaluated by electronic search. Because of controversial results especially in immediate loading and animal studies, further modified research is needed to establish the mechanism and effect of the PLS technique. Essential changes in studies including using the control group for accurate interpretation of results and long-term observation, particularly through, randomized, prospective, multicenter trials with large numbers of participants, and implants are necessary.

  5. Some observational results of sea storm current

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    @@ INTRODUCTION Dr. Hollister, a marine geologist of the Woods Hole Oceanographic Institution, first pointed out that there was ocean storm current in the ocean. He found out the wavy texture in the seabed core samples, and suggested that this wavy texture was caused by the high speed sea current in remote antiquity. He then suggested a bold hypothesis that there existed a benthic storm current near the ocean bottom, and presented this hypothesis at the IUGG conference held at San Francisco in 1963. Unfortunately, the attention was not drawn to the hypothesis at the conference, and the hypothesis was criticized as a sheer nonsense.

  6. Numerical Analysis of Induced Current in Human Head Exposed to Nonuniform Magnetic Field Including Harmonics

    Science.gov (United States)

    Tarao, Hiroo; Hayashi, Noriyuki; Isaka, Katsuo

    In this paper, induced currents in an anatomical head model exposed to a non-uniform ELF magnetic field (B-field) including harmonics are numerically calculated, and are discussed based on the basic restriction established by International Commission on Non-Ionizing Radiation Protection (ICNIRP). A casual hair dryer of 100V and 1.2kW is chosen as a typical source of the non-uniform B-field including both the fundamental and second harmonic components. The B-field distribution around the hair dryer is estimated by using the 3-orthogonal magnetic dipole moments, which are derived from a couple of measured values around it. The high-resolution human head model used is constructed based on the MRI images of a real human, and consists of six kinds of tissues (bone, brain, eyeballs, muscle, skin and blood). So-called impedance method is used for the numerical calculation of the induced current. The numerical results show that the maximum values of the induced current of 17µA/m2, for the 60Hz component, which is about 1/120 of the ICNIRP basic restriction appear in the muscle near the eyeball when the hair dryer is used from the side of the head model, and the averaged current in the eyeballs that have the highest conductivity is the highest among the six tissues. It is also demonstrated that the induced current due to the 120Hz B-field becomes comparable to the 60Hz current although the magnitude of the 120Hz B-field is much smaller than that of the 60Hz B-field.

  7. Numerical analysis of global ionospheric current system including the effect of equatorial enhancement

    Directory of Open Access Journals (Sweden)

    S. Tsunomura

    Full Text Available A modeling method is proposed to derive a two-dimensional ionospheric layer conductivity, which is appropriate to obtain a realistic solution of the polar-originating ionospheric current system including equatorial enhancement. The model can be obtained by modifying the conventional, thin shell conductivity model. It is shown that the modification for one of the non-diagonal terms (Σθφ in the conductivity tensor near the equatorial region is very important; the term influences the profile of the ionospheric electric field around the equator drastically. The proposed model can reproduce well the results representing the observed electric and magnetic field signatures of geomagnetic sudden commencement. The new model is applied to two factors concerning polar-originating ionospheric current systems. First, the latitudinal profile of the DP2 amplitude in the daytime is examined, changing the canceling rate for the dawn-to-dusk electric field by the region 2 field-aligned current. It is shown that the equatorial enhancement would not appear when the ratio of the total amount of the region 2 field-aligned current to that of region 1 exceeds 0.5. Second, the north-south asymmetry of the magnetic fields in the summer solstice condition of the ionospheric conductivity is examined by calculating the global ionospheric current system covering both hemispheres simultaneously. It is shown that the positive relationship between the magnitudes of high latitude magnetic fields and the conductivity is clearly seen if a voltage generator is given as the source, while the relationship is vague or even reversed for a current generator. The new model, based on the International Reference Ionosphere (IRI model, can be applied to further investigations in the quantitative analysis of the magnetosphere-ionosphere coupling problems.

    Key words. Ionosphere (electric fields and currents; equatorial ionosphere; ionosphere

  8. Recent experimental results of KSTAR RF heating and current drive

    Energy Technology Data Exchange (ETDEWEB)

    Wang, S. J., E-mail: sjwang@nfri.re.kr; Kim, J.; Jeong, J. H.; Kim, H. J.; Joung, M.; Bae, Y. S.; Kwak, J. G. [National Fusion Research Institute, Daejoen, 305-806 (Korea, Republic of)

    2015-12-10

    The overview of KSTAR activities on ICRH, LHCD and ECH/CD including the last experimental results and future plan aiming for long-pulse high-beta plasma will be presented. Recently we achieved reasonable coupling of ICRF power to H-mode plasma through several efforts to increase system reliability. Power balance will be discussed on this experiment. LHCD is still struggling in the low power regime. Review of antenna spectrum for the higher coupling in H-mode plasma will be tried. ECH/CD provides 41 sec, 0.8 MW of heating power to support high-performance long-pulse discharge. Also, 170 GHz ECH system is integrated with the Plasma Control System (PCS) for the feedback controlling of NTM. Status and plan of ECH/CD will be discussed. Finally, helicon current drive is being prepared for the next stage of KSTAR operation. The hardware preparation and the calculation results of helicon current drive in KSTAR plasma will be discussed.

  9. An induction machine model including interbar currents for studying performances during transients and steady state

    Energy Technology Data Exchange (ETDEWEB)

    Razik, H. [Universite Henri Poincare, GREEN, CNRS-UMR 7037, BP 239, F-54506 Vandoeuvre-les-Nancy Cedex (France); Henao, H. [University of Picardie, CREA, 33 rue Saint Leu, F-80039 Amiens Cedex 1 (France); Carlson, R. [GRUCAD/CTC/UFSC, Campus Universitario, C.P. 436, Florianopolis - SC, 88040-900 (Brazil)

    2009-01-15

    This paper presents a mathematical model of a three-phase induction motor taking into consideration the interbar contacts. Several models have been available in the references. However, they consider the rotor of the induction motor as being constituted either a three-phase or a squirrel cage even if it operates under stator and/or rotor faults condition. Nonetheless, the contact between a bar and the iron core for the machine has to be considered, especially when a rotor fault occurs. It is obvious that rotor currents are under the influence of rotor constitution materials. So, the paper aim's concerns a transient model of the induction motors which can consider the rotor broken bars defect. Despite its increasing complexity, it could be able to provide with useful indications for diagnostic purposes. This model is advocated for the simulation of motors behavior under rotor defect which takes into account the interbar currents. The proposed technique is based on the mesh model analysis of the squirrel cage. As low power induction motors are prevalent in industrial plants, we pay a special attention on them. Notwithstanding, additional currents are due to the contact between the non-insulated bar constituting the squirrel cage to the rotor iron core. The monitoring of induction motors is predominantly made through the stator current analysis of the motor when it operates at nominal condition. Moreover, this one is observed in steady state operating system, knowing that the motor is generally fed by a sinusoidal supply. Consequently, simulation results showed in this paper prove the effectiveness of the proposed approach, and the impact of interbar resistance both on the model and the line current spectrum for the diagnostic. An experimental test proves the effectiveness of this model. (author)

  10. Including Alternative Resources in State Renewable Portfolio Standards: Current Design and Implementation Experience

    Energy Technology Data Exchange (ETDEWEB)

    Heeter, J.; Bird, L.

    2012-11-01

    Currently, 29 states, the District of Columbia, and Puerto Rico have instituted a renewable portfolio standard (RPS). An RPS sets a minimum threshold for how much renewable energy must be generated in a given year. Each state policy is unique, varying in percentage targets, timetables, and eligible resources. This paper examines state experience with implementing renewable portfolio standards that include energy efficiency, thermal resources, and non-renewable energy and explores compliance experience, costs, and how states evaluate, measure, and verify energy efficiency and convert thermal energy. It aims to gain insights from the experience of states for possible federal clean energy policy as well as to share experience and lessons for state RPS implementation.

  11. Electrolytic/fuel cell bundles and systems including a current collector in communication with an electrode thereof

    Science.gov (United States)

    Hawkes, Grant L.; Herring, James S.; Stoots, Carl M.; O& #x27; Brien, James E.

    2013-03-05

    Electrolytic/fuel cell bundles and systems including such bundles include an electrically conductive current collector in communication with an anode or a cathode of each of a plurality of cells. A cross-sectional area of the current collector may vary in a direction generally parallel to a general direction of current flow through the current collector. The current collector may include a porous monolithic structure. At least one cell of the plurality of cells may include a current collector that surrounds an outer electrode of the cell and has at least six substantially planar exterior surfaces. The planar surfaces may extend along a length of the cell, and may abut against a substantially planar surface of a current collector of an adjacent cell. Methods for generating electricity and for performing electrolysis include flowing current through a conductive current collector having a varying cross-sectional area.

  12. Westinghouse accident tolerant fuel program. Current results and future plans

    Energy Technology Data Exchange (ETDEWEB)

    Ray, Sumit; Xu, Peng; Lahoda, Edward; Hallstadius, Lars; Boylan, Frank [Westinghouse Electric Company LLC, Hopkins, SC (United States)

    2016-07-15

    This paper discusses the current status, results from initial tests, as well as the future direction of the Westinghouse's Accident Tolerant Fuel (ATF) program. The current preliminary testing is addressed that is being performed on these samples at the Massachusetts Institute of Technology (MIT) test reactor, initial results from these tests, as well as the technical learning from these test results. In the Westinghouse ATF approach, higher density pellets play a significant role in the development of an integrated fuel system.

  13. 75 FR 22630 - Nautilus, Inc., Currently Known as Med-Fit Systems Incorporated, Commercial Division, Including...

    Science.gov (United States)

    2010-04-29

    ..., Virginia. The notice was published in the Federal Register on February 16th, 2010 (75 FR 7032). At the... Employment and Training Administration Nautilus, Inc., Currently Known as Med-Fit Systems Incorporated.... was sold in September 2009 and is currently known as Med-Fit Systems, Incorporated. Some...

  14. Equivalent Circuit for Cavity Discharges Including Controlled Current Source and Controlled Switch

    Institute of Scientific and Technical Information of China (English)

    CHEN Weigen; CHEN Xi; XIE Bo; LIU Jun

    2013-01-01

    Numerous equivalent circuits for cavity discharges have been developed,yet most of these models cannot provide simulated signals that precisely reveal the variability of the discharge's characteristic parameters,such as repetition rate,magnitude and phase of discharges,which makes them not suitable for intensive studies of discharge process.Therefore,using Simulink code,we theoretically analyzed and studied the classical equivalent circuits of cavity discharges,as well as the influence of circuit components on simulation results,and then proposed a novel equivalent circuit,the key parameters of which were determined according to the physical behavior of cavity discharges.In the novel equivalent circuit,the repetition rate can be changed by discharge resistance,inception and residual voltages;meanwhile the phase of discharge can be controlled by adjusting the parameters of shunt resistance.Furthermore,a controlled current source as a function of space charge is introduced in the equivalent circuit.Compared with the former ones,the simulated signals obtained by this novel model are better approximation of real signals.This work could be referred by latter studies of the characteristics and the mechanisms of cavity discharge in oil-paper insulation.

  15. Non-linear Simulations of MHD Instabilities in Tokamaks Including Eddy Current Effects and Perspectives for the Extension to Halo Currents

    Science.gov (United States)

    Hoelzl, M.; Huijsmans, G. T. A.; Merkel, P.; Atanasiu, C.; Lackner, K.; Nardon, E.; Aleynikova, K.; Liu, F.; Strumberger, E.; McAdams, R.; Chapman, I.; Fil, A.

    2014-11-01

    The dynamics of large scale plasma instabilities can be strongly influenced by the mutual interaction with currents flowing in conducting vessel structures. Especially eddy currents caused by time-varying magnetic perturbations and halo currents flowing directly from the plasma into the walls are important. The relevance of a resistive wall model is directly evident for Resistive Wall Modes (RWMs) or Vertical Displacement Events (VDEs). However, also the linear and non-linear properties of most other large-scale instabilities may be influenced significantly by the interaction with currents in conducting structures near the plasma. The understanding of halo currents arising during disruptions and VDEs, which are a serious concern for ITER as they may lead to strong asymmetric forces on vessel structures, could also benefit strongly from these non-linear modeling capabilities. Modeling the plasma dynamics and its interaction with wall currents requires solving the magneto-hydrodynamic (MHD) equations in realistic toroidal X-point geometry consistently coupled with a model for the vacuum region and the resistive conducting structures. With this in mind, the non-linear finite element MHD code JOREK [1, 2] has been coupled [3] with the resistive wall code STARWALL [4], which allows us to include the effects of eddy currents in 3D conducting structures in non-linear MHD simulations. This article summarizes the capabilities of the coupled JOREK-STARWALL system and presents benchmark results as well as first applications to non-linear simulations of RWMs, VDEs, disruptions triggered by massive gas injection, and Quiescent H-Mode. As an outlook, the perspectives for extending the model to halo currents are described.

  16. Micromagnetic model for studies on Magnetic Tunnel Junction switching dynamics, including local current density

    Energy Technology Data Exchange (ETDEWEB)

    Frankowski, Marek, E-mail: mfrankow@agh.edu.pl; Czapkiewicz, Maciej; Skowronski, Witold; Stobiecki, Tomasz

    2014-02-15

    We present a model introducing the Landau–Lifshitz–Gilbert equation with a Slonczewski's Spin-Transfer-Torque (STT) component in order to take into account spin polarized current influence on the magnetization dynamics, which was developed as an Object Oriented MicroMagnetic Framework extension. We implement the following computations: magnetoresistance of vertical channels is calculated from the local spin arrangement, local current density is used to calculate the in-plane and perpendicular STT components as well as the Oersted field, which is caused by the vertical current flow. The model allows for an analysis of all listed components separately, therefore, the contribution of each physical phenomenon in dynamic behavior of Magnetic Tunnel Junction (MTJ) magnetization is discussed. The simulated switching voltage is compared with the experimental data measured in MTJ nanopillars.

  17. A Physics-Based Charge-Control Model for InP DHBT Including Current-Blocking Effect

    Institute of Scientific and Technical Information of China (English)

    GE Ji; JIN Zhi; SU Yong-Bo; CHENG Wei; WANG Xian-Wai; CHEN Gao-Peng; LIU Xin-Yu

    2009-01-01

    We develop a physics-based charge-control InP double heterojunction bipolar transistor model including three important effects: current blocking, mobile-charge modulation of the base-collector capacitance and velocity-field modulation in the transit time. The bias-dependent base-collector depletion charge is obtained analytically, which takes into account the mobile-charge modulation. Then, a measurement based voltage-dependent transit time formulation is implemented. As a result, over a wide range of biases, the developed model shows good agreement between the modeled and measured S-parameters and cutoff frequency. Also, the model considering current blocking effect demonstrates more accurate prediction of the output characteristics than conventional vertical bipolar inter company results.

  18. Current developments in avian influenza vaccines, including safety of vaccinated birds as food.

    Science.gov (United States)

    Swayne, D E; Suarez, D L

    2007-01-01

    Until recently, most vaccines against avian influenza were based on oil-emulsified inactivated low- or high-pathogenicity viruses. Now, recombinant fowl pox and avian paramyxovirus type 1 vaccines with avian influenza H5 gene inserts (+ or - N1 gene insert) are available and licensed. New technologies might overcome existing limitations to make available vaccines that can be grown in tissue culture systems for more rapid production; provide optimized protection, as a result of closer genetic relations to field viruses; allow mass administration by aerosol, in drinking-water or in ovo; and allow easier strategies for identifying infected birds within vaccinated populations (DIVA). The technologies include avian influenza viruses with partial gene deletions, avian influenza-Newcastle disease virus chimeras, vectored vaccines such as adenoviruses and Marek's disease virus, and subunit vaccines. These new methods should be licensed only after their purity, safety, efficacy and potency against avian influenza viruses have been demonstrated, and, for live vectored vaccines, restriction of viral transmission to unvaccinated birds. Use of vaccines in countries affected by highly pathogenic avian influenza will not only protect poultry but will provide additional safety for consumers. Experimental studies have shown that birds vaccinated against avian influenza have no virus in meat and minimal amounts in eggs after HPAI virus challenge, and that replication and shedding from their respiratory and alimentary tracts is greatly reduced.

  19. Cellulite treatment: evidence and ethics, brief history, and emphasis on current practices including liposuction

    Science.gov (United States)

    de Riese, Cornelia

    2005-04-01

    According to Taber's Cyclopedic Medical Dictionary "cellulite" is defined as: "a non-technical term for subcutaneous deposits of fat, especially in the buttocks, legs, and thighs." These deposits result in puckered, dimply skin and they are a cause for major aesthetic concerns in affected patients. The etiology of this condition is still unclear. Female predilection is witnessed in clinical practice as it is reported in the literature. It remains a subject for further studies whether it is a structural problem of connective tissue or as suggested probably related to hormonal causes. Magnetic resonance imaging may provide some answers to these questions. Not knowing what is causing this nuisance makes it almost impossible to treat. No wonder that there is little scientific validation to support any of the many treatments that are advertised on the Internet or in women's magazines. This review focuses on mechanical and microinvasive interventions that claim to alleviate "cellulite": lipoplasty, liposcultpure, liposuction, subcision, and laser. Among the parameters analyzed are the proposed modes of action of these techniques as well as adverse events and complications that may occur. Of special interest will be the evidence that backs these procedures. Extracting reliable data is hampered by methodical problems with the design of most of the published trials. In essence, at this time there is no "cure" for cellulite. Safe treatment recommendations are related to healthy life style choices that include toning exercises, dietary changes, and weight loss.

  20. Improved exponential convergence result for generalized neural networks including interval time-varying delayed signals.

    Science.gov (United States)

    Rajchakit, G; Saravanakumar, R; Ahn, Choon Ki; Karimi, Hamid Reza

    2017-02-01

    This article examines the exponential stability analysis problem of generalized neural networks (GNNs) including interval time-varying delayed states. A new improved exponential stability criterion is presented by establishing a proper Lyapunov-Krasovskii functional (LKF) and employing new analysis theory. The improved reciprocally convex combination (RCC) and weighted integral inequality (WII) techniques are utilized to obtain new sufficient conditions to ascertain the exponential stability result of such delayed GNNs. The superiority of the obtained results is clearly demonstrated by numerical examples.

  1. 75 FR 70688 - Actel Corporation, Currently Known as Microsemi Corporation, Including On-Site Leased Workers...

    Science.gov (United States)

    2010-11-18

    ... On-Site Leased Workers From ATR International, Accountants, Inc. and Accountant Temps Mountain View... International, Accountants, Inc., and Accountant Temps, Mountain View, California. The notice was published in... Microsemi Corporation, including on-site leased workers from ATE International, Accountants, Inc.,...

  2. Current Changes in Pubertal Timing: Revised Vision in Relation with Environmental Factors Including Endocrine Disruptors.

    Science.gov (United States)

    Parent, Anne-Simone; Franssen, Delphine; Fudvoye, Julie; Pinson, Anneline; Bourguignon, Jean-Pierre

    2016-01-01

    The aim of this chapter is to revise some common views on changes in pubertal timing. This revision is based on recent epidemiological findings on the clinical indicators of pubertal timing and data on environmental factor effects and underlying mechanisms. A current advancement in timing of female puberty is usually emphasized. It appears, however, that timing is also changing in males. Moreover, the changes are towards earliness for initial pubertal stages and towards lateness for final stages in both sexes. Such observations indicate the complexity of environmental influences on pubertal timing. The mechanisms of changes in pubertal timing may involve both the central neuroendocrine control and peripheral effects at tissues targeted by gonadal steroids. While sufficient energy availability is a clue to the mechanism of pubertal development, changes in the control of both energy balance and reproduction may vary under the influence of common determinants such as endocrine-disrupting chemicals (EDCs). These effects can take place right before puberty as well as much earlier, during fetal and neonatal life. Finally, environmental factors can interact with genetic factors in determining changes in pubertal timing. Therefore, the variance in pubertal timing is no longer to be considered under absolutely separate control by environmental and genetic determinants. Some recommendations are provided for evaluation of EDC impact in the management of pubertal disorders and for possible reduction of EDC exposure along the precautionary principle.

  3. Electromagnetic Flow Meter Having a Driver Circuit Including a Current Transducer

    Science.gov (United States)

    Karon, David M. (Inventor); Cushing, Vincent (Inventor); Patel, Sandeep K. (Inventor)

    2014-01-01

    An electromagnetic flow meter (EMFM) accurately measures both the complete flow rate and the dynamically fluctuating flow rate of a fluid by applying a unipolar DC voltage to excitation coils for a predetermined period of time, measuring the electric potential at a pair of electrodes, determining a complete flow rate and independently measuring the dynamic flow rate during the "on" cycle of the DC excitation, and correcting the measurements for errors resulting from galvanic drift and other effects on the electric potential. The EMFM can also correct for effects from the excitation circuit induced during operation of the EMFM.

  4. Recent results on current profile shaping on tore supra

    Energy Technology Data Exchange (ETDEWEB)

    Becoulet, A.

    1994-12-31

    The link between the current profile and the confinement is studied, involving various regimes: high power minority ion cyclotron resonant heating, high power lower hybrid current drive, fast wave direct electron heating and current drive and pellet enhanced performance. It is shown that the electron heat diffusivity decreases when the magnetic shear increases in the confinement zone and/or when it decreases in the plasma centre. (authors). 13 refs., 6 figs.

  5. Web-Scale Discovery Services Retrieve Relevant Results in Health Sciences Topics Including MEDLINE Content

    Directory of Open Access Journals (Sweden)

    Elizabeth Margaret Stovold

    2017-06-01

    Full Text Available A Review of: Hanneke, R., & O’Brien, K. K. (2016. Comparison of three web-scale discovery services for health sciences research. Journal of the Medical Library Association, 104(2, 109-117. http://dx.doi.org/10.3163/1536-5050.104.2.004 Abstract Objective – To compare the results of health sciences search queries in three web-scale discovery (WSD services for relevance, duplicate detection, and retrieval of MEDLINE content. Design – Comparative evaluation and bibliometric study. Setting – Six university libraries in the United States of America. Subjects – Three commercial WSD services: Primo, Summon, and EBSCO Discovery Service (EDS. Methods – The authors collected data at six universities, including their own. They tested each of the three WSDs at two data collection sites. However, since one of the sites was using a legacy version of Summon that was due to be upgraded, data collected for Summon at this site were considered obsolete and excluded from the analysis. The authors generated three questions for each of six major health disciplines, then designed simple keyword searches to mimic typical student search behaviours. They captured the first 20 results from each query run at each test site, to represent the first “page” of results, giving a total of 2,086 total search results. These were independently assessed for relevance to the topic. Authors resolved disagreements by discussion, and calculated a kappa inter-observer score. They retained duplicate records within the results so that the duplicate detection by the WSDs could be compared. They assessed MEDLINE coverage by the WSDs in several ways. Using precise strategies to generate a relevant set of articles, they conducted one search from each of the six disciplines in PubMed so that they could compare retrieval of MEDLINE content. These results were cross-checked against the first 20 results from the corresponding query in the WSDs. To aid investigation of overall

  6. A unified analytical drain current model for Double-Gate Junctionless Field-Effect Transistors including short channel effects

    Science.gov (United States)

    Raksharam; Dutta, Aloke K.

    2017-04-01

    In this paper, a unified analytical model for the drain current of a symmetric Double-Gate Junctionless Field-Effect Transistor (DG-JLFET) is presented. The operation of the device has been classified into four modes: subthreshold, semi-depleted, accumulation, and hybrid; with the main focus of this work being on the accumulation mode, which has not been dealt with in detail so far in the literature. A physics-based model, using a simplified one-dimensional approach, has been developed for this mode, and it has been successfully integrated with the model for the hybrid mode. It also includes the effect of carrier mobility degradation due to the transverse electric field, which was hitherto missing in the earlier models reported in the literature. The piece-wise models have been unified using suitable interpolation functions. In addition, the model includes two most important short-channel effects pertaining to DG-JLFETs, namely the Drain Induced Barrier Lowering (DIBL) and the Subthreshold Swing (SS) degradation. The model is completely analytical, and is thus computationally highly efficient. The results of our model have shown an excellent match with those obtained from TCAD simulations for both long- and short-channel devices, as well as with the experimental data reported in the literature.

  7. Comparing the results of DAADD and ABC of children included in autism spectrum disorders.

    Science.gov (United States)

    Barbosa, Milene Rossi Pereira; Fernandes, Fernanda Dreux Miranda

    2014-01-01

    To verify if there are characteristic behaviors of the different diagnosis included in the autism spectrum according to the Differential Assessment of Autism and Other Developmental Disorders (DAADD) and to the Autism Behavior Checklist (ABC). Participants were 45 individuals and their respective speech-language therapists. All therapists are graduate students working with the children for at least 1 year. This time was considered sufficient to the therapists to have the information required by the DAADD questionnaire. It is comprised by 3 protocols specifically designed to children with 2 to 4 years, 4 to 6 years and 6 to 8 years, the same criteria used to separate the research groups, G1, G2 and G3, respectively. Data referring to the ABC were retrieved from the subject's files at the Laboratório de Investigação Fonoaudiológica nos Distúrbios do Espectro do Autismo (Research Laboratory on Language Disorders in the Autism Spectrum) of the School of Medicine, Universidade de São Paulo, where it is routinely applied during the annual assessment. Answers to the different areas of DAADD are similar to the different areas of ABC. These data show data the diagnosis by DAADD is easier in older children. Although there is no significant difference, the large occurrence of Rett's syndrome diagnosis according to the DAADD was associated to higher risk for autism according to the ABC in G1. With increasing age this tendency decreases and either in G2 and G3 Autism is the most frequent diagnosis. Although the results of both questionnaires tend to agree more with increasing age, the DAADD is more sensitive in the different ages while the ABC if more specific only to older children.

  8. Current Trends in Nursing Informatics: Results of an International Survey.

    Science.gov (United States)

    Peltonen, Laura-Maria; Alhuwail, Dari; Ali, Samira; Badger, Martha K; Eler, Gabrielle Jacklin; Georgsson, Mattias; Islam, Tasneem; Jeon, Eunjoo; Jung, Hyunggu; Kuo, Chiu-Hsiang; Lewis, Adrienne; Pruinelli, Lisiane; Ronquillo, Charlene; Sarmiento, Raymond Francis; Sommer, Janine; Tayaben, Jude L; Topaz, Maxim

    2016-01-01

    Nursing informatics (NI) can help provide effective and safe healthcare. This study aimed to describe current research trends in NI. In the summer 2015, the IMIA-NI Students Working Group created and distributed an online international survey of the current NI trends. A total of 402 responses were submitted from 44 countries. We identified a top five NI research areas: standardized terminologies, mobile health, clinical decision support, patient safety and big data research. NI research funding was considered to be difficult to acquire by the respondents. Overall, current NI research on education, clinical practice, administration and theory is still scarce, with theory being the least common. Further research is needed to explain the impact of these trends and the needs from clinical practice.

  9. San Juan Fracture Characterization Project: Status and current results

    Energy Technology Data Exchange (ETDEWEB)

    Majer, E.L.; Daley, T.M.; Myer, L.R.; Nihei, K.; Queen, J.; Sinton, J.; Murphy, J.; Fortuna, M.; Lynn, H.B.; Imhoff, M.A.; Wilson, R.

    2001-02-26

    The overall objectives of this report are to extend current state-of-the-art 3-D imaging to extract the optimal information for fracture quantification and to develop next generation capability in fracture imaging for true 3-D imaging of the static and dynamic fracture properties.

  10. Endometrial cancer risk prediction including serum-based biomarkers : results from the EPIC cohort

    NARCIS (Netherlands)

    Fortner, Renée T.; Hüsing, Anika; Kühn, Tilman; Konar, Meric; Overvad, Kim; Tjønneland, Anne; Hansen, Louise; Boutron-Ruault, Marie Christine; Severi, Gianluca; Fournier, Agnès; Boeing, Heiner; Trichopoulou, Antonia; Benetou, Vasiliki; Orfanos, Philippos; Masala, Giovanna; Agnoli, Claudia; Mattiello, Amalia; Tumino, Rosario; Sacerdote, Carlotta; Bueno-de-Mesquita, H. Bas; Peeters, Petra H M; Weiderpass, Elisabete; Gram, Inger T.; Gavrilyuk, Oxana; Quirós, J. Ramón; Maria Huerta, José; Ardanaz, Eva; Larrañaga, Nerea; Lujan-Barroso, Leila; Sánchez-Cantalejo, Emilio; Butt, Salma Tunå; Borgquist, Signe; Idahl, Annika; Lundin, Eva; Khaw, Kay Tee; Allen, Naomi E.; Rinaldi, Sabina; Dossus, Laure; Gunter, Marc; Merritt, Melissa A.; Tzoulaki, Ioanna; Riboli, Elio; Kaaks, Rudolf

    2017-01-01

    Endometrial cancer risk prediction models including lifestyle, anthropometric and reproductive factors have limited discrimination. Adding biomarker data to these models may improve predictive capacity; to our knowledge, this has not been investigated for endometrial cancer. Using a nested

  11. Endometrial cancer risk prediction including serum-based biomarkers: results from the EPIC cohort.

    Science.gov (United States)

    Fortner, Renée T; Hüsing, Anika; Kühn, Tilman; Konar, Meric; Overvad, Kim; Tjønneland, Anne; Hansen, Louise; Boutron-Ruault, Marie-Christine; Severi, Gianluca; Fournier, Agnès; Boeing, Heiner; Trichopoulou, Antonia; Benetou, Vasiliki; Orfanos, Philippos; Masala, Giovanna; Agnoli, Claudia; Mattiello, Amalia; Tumino, Rosario; Sacerdote, Carlotta; Bueno-de-Mesquita, H B As; Peeters, Petra H M; Weiderpass, Elisabete; Gram, Inger T; Gavrilyuk, Oxana; Quirós, J Ramón; Maria Huerta, José; Ardanaz, Eva; Larrañaga, Nerea; Lujan-Barroso, Leila; Sánchez-Cantalejo, Emilio; Butt, Salma Tunå; Borgquist, Signe; Idahl, Annika; Lundin, Eva; Khaw, Kay-Tee; Allen, Naomi E; Rinaldi, Sabina; Dossus, Laure; Gunter, Marc; Merritt, Melissa A; Tzoulaki, Ioanna; Riboli, Elio; Kaaks, Rudolf

    2017-03-15

    Endometrial cancer risk prediction models including lifestyle, anthropometric and reproductive factors have limited discrimination. Adding biomarker data to these models may improve predictive capacity; to our knowledge, this has not been investigated for endometrial cancer. Using a nested case-control study within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort, we investigated the improvement in discrimination gained by adding serum biomarker concentrations to risk estimates derived from an existing risk prediction model based on epidemiologic factors. Serum concentrations of sex steroid hormones, metabolic markers, growth factors, adipokines and cytokines were evaluated in a step-wise backward selection process; biomarkers were retained at p risk estimates. We used internal validation with bootstrapping (1000-fold) to adjust for over-fitting. Adiponectin, estrone, interleukin-1 receptor antagonist, tumor necrosis factor-alpha and triglycerides were selected into the model. After accounting for over-fitting, discrimination was improved by 2.0 percentage points when all evaluated biomarkers were included and 1.7 percentage points in the model including the selected biomarkers. Models including etiologic markers on independent pathways and genetic markers may further improve discrimination. © 2016 UICC.

  12. Target echo strength modelling at FOI, including results from the BeTSSi II workshop

    CERN Document Server

    Östberg, Martin

    2016-01-01

    An overview of the target echo strength (TS) modelling capacity at the Swedish Defense Research Agency (FOI) is presented. The modelling methods described range from approximate ones, such as raytracing and Kirchhoff approximation codes, to high accuracy full field codes including boundary integral equation methods and finite elements methods. Illustrations of the applicability of the codes are given for a few simple cases tackled during the BeTTSi II (Benchmark Target Echo Strength Simulation) workshop held in Kiel 2014.

  13. New results on top-quark mass, including new methods, in ATLAS

    CERN Document Server

    Yau Wong, Kaven Henry; The ATLAS collaboration

    2016-01-01

    Recent results on top-quark mass measurements with the ATLAS detector using proton-proton collisions at the Large Hadron Collider are presented. These results correspond to the measurements in the $t\\bar{t}$ all-hadronic and dilepton channels at $\\sqrt{s} = \\mathrm{8\\ TeV}$ collisions and an integrated luminosity of 20 $\\mathrm{fb}^{-1}$.

  14. Ergotism unresponsive to multiple therapeutic modalities, including sodium nitroprusside, resulting in limb loss.

    Science.gov (United States)

    Musikatavorn, Khrongwong; Suteparuk, Suchai

    2008-02-01

    Unlike epidemics in past centuries, patients suffering from peripheral vascular ischemia related to ergotism now rarely lose a limb because of vasodilator therapies. We report a patient with ischemia from ergotamine tartrate who failed to recover with medical therapy, resulting in limb amputation.

  15. Experimental results for the Poincar\\'e center problem (including an Appendix with Martin Cremer)

    OpenAIRE

    Bothmer, Hans-Christian Graf v.

    2005-01-01

    Comment: 16 pages, 2 figures, source code of programs at http://www-ifm.math.uni-hannover.de/~bothmer/strudel/. Added references, the result of Example 6.2 is not new. Added two new sections on rationally reversible systems. The 4th codim 7 component we saw only experimentally can now also be identified geometricaly

  16. Bilateral cochlear implantation: current concepts, indications, and results.

    Science.gov (United States)

    Basura, Gregory J; Eapen, Rose; Buchman, Craig A

    2009-12-01

    The optimal treatment for bilateral hearing loss continues to evolve as cochlear implant (CI) and hearing aid technologies advance, as does our understanding of the central auditory system. Ongoing discussions continue on the validity and feasibility of bilateral CI in terms of performance, justification of need, medical/surgical safety concerns, and economics. The purpose of this review article is to provide an update on the advantages and disadvantages of bilateral CI and to provide a discussion on timing (simultaneous vs. sequential), technology (bimodal vs. binaural) and feasibility. Binaural advantages are found in both adult and pediatric bilateral CI recipients, the greatest being the head shadow effect and improvements in localization and loudness summation. This theoretically offers an advantage over their unilateral implanted counterparts in terms of improved sound localization and enhanced speech perception under noisy conditions. Most investigators agree that bilateral stimulation during critical periods of development is paramount for optimizing auditory functioning in children. Currently, bilateral CI is widely accepted as a safe and effective means of bilateral auditory stimulation.

  17. On the Determination of Concrete Armour Unit Stress including Specific Results related to Dolosse

    DEFF Research Database (Denmark)

    Burcharth, H. F.; Howell, G.L.; Liu, Z.

    1991-01-01

    Failures of rubble mound breakwaters armoured with complex types of unreinforced concrete armour units are often due to breakage. This happens when the stresses exceed the material strength. Sufficient parametric studies of the stresses are not yet available to produce design diagrams for structu......Failures of rubble mound breakwaters armoured with complex types of unreinforced concrete armour units are often due to breakage. This happens when the stresses exceed the material strength. Sufficient parametric studies of the stresses are not yet available to produce design diagrams...... for structural integrity. The paper presents a general discussion of the problems related to stress etermination and describes the results and the analyses of model tests with 200 kg and 200 g load-cell instrumented Dolosse. Static stresses, wave-generate stresses due to impacts were studied as well as model...

  18. Globular Cluster Populations: Results Including S$^4$G Late-Type Galaxies

    CERN Document Server

    Zaritsky, Dennis; Aravena, Manuel; Athanassoula, E; Bosma, Albert; Comerón, Sébastien; Courtois, Helene M; Elmegreen, Bruce G; Elmegreen, Debra M; Erroz-Ferrer, Santiago; Gadotti, Dimitri A; Hinz, Joannah L; Ho, Luis C; Holwerda, Benne; Kim, Taehyun; Knapen, Johan H; Laine, Jarkko; Laurikainen, Eija; Muñoz-Mateos, Juan Carlos; Salo, Heikki; Sheth, Kartik

    2015-01-01

    Using 3.6 and 4.5$\\mu$m images of 73 late-type, edge-on galaxies from the S$^4$G survey, we compare the richness of the globular cluster populations of these galaxies to those of early type galaxies that we measured previously. In general, the galaxies presented here fill in the distribution for galaxies with lower stellar mass, M$_*$, specifically $\\log({\\rm M}_*/{\\rm M}_\\odot) < 10$, overlap the results for early-type galaxies of similar masses, and, by doing so, strengthen the case for a dependence of the number of globular clusters per $10^9\\ {\\rm M}_\\odot$ of galaxy stellar mass, T$_{\\rm N}$, on M$_*$. For $8.5 < \\log ({\\rm M}_*/{\\rm M}_\\odot) < 10.5$ we find the relationship can be satisfactorily described as T$_{\\rm N} = ({\\rm M}_*/10^{6.7})^{-0.56}$ when M$_*$ is expressed in solar masses. The functional form of the relationship is only weakly constrained and extrapolation outside this range is not advised. Our late-type galaxies, in contrast to our early-types, do not show the tendency for l...

  19. A Multiobjective Optimization Including Results of Life Cycle Assessment in Developing Biorenewables-Based Processes.

    Science.gov (United States)

    Helmdach, Daniel; Yaseneva, Polina; Heer, Parminder K; Schweidtmann, Artur M; Lapkin, Alexei A

    2017-09-22

    A decision support tool has been developed that uses global multiobjective optimization based on 1) the environmental impacts, evaluated within the framework of full life cycle assessment; and 2) process costs, evaluated by using rigorous process models. This approach is particularly useful in developing biorenewable-based energy solutions and chemicals manufacturing, for which multiple criteria must be evaluated and optimization-based decision-making processes are particularly attractive. The framework is demonstrated by using a case study of the conversion of terpenes derived from biowaste feedstocks into reactive intermediates. A two-step chemical conversion/separation sequence was implemented as a rigorous process model and combined with a life cycle model. A life cycle inventory for crude sulfate turpentine was developed, as well as a conceptual process of its separation into pure terpene feedstocks. The performed single- and multiobjective optimizations demonstrate the functionality of the optimization-based process development and illustrate the approach. The most significant advance is the ability to perform multiobjective global optimization, resulting in identification of a region of Pareto-optimal solutions. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  20. Current Results and Future Directions of the Pulsar Search Collaboratory

    Science.gov (United States)

    Heatherly, Sue Ann; Rosen, R.; McLaughlin, M.; Lorimer, D.

    2011-01-01

    The Pulsar Search Collaboratory (PSC) is a joint partnership between the National Radio Astronomy Observatory (NRAO) and West Virginia University (WVU). The ultimate goal of the PSC is to interest students in science, technology, engineering, mathematics (STEM) fields by engaging them in conducting authentic scientific research-specifically the search for new pulsars. Of the 33 schools in the original PSC program, 13 come from rural school districts; one third of these are from schools where over 50% participate in the Free/Reduced School Lunch program. We are reaching first generation college-goers. For students, the program succeeds in building confidence in students, rapport with the scientists involved in the project, and greater comfort with team-work. We see additional gains in girls, as they see themselves more as scientists after participating in the PSC program, which is an important predictor of success in STEM fields. The PSC has had several scientific successes as well. To date, PSC students have made two astronomical discoveries: a 4.8-s pulsar and bright radio burst of astrophysical origin, most likely from a sporadic neutron star. We will report on the status of the project including new evaluation data. We will also describe PSC-West, an experiment to involve schools in Illinois and Wisconsin using primarily online tools for professional development of teachers and coaching of students. Knowledge gained through our efforts with PSC-West will assist the PSC team in scaling up the project.

  1. Immobilized cell technology in beer brewing: Current experience and results

    Directory of Open Access Journals (Sweden)

    Leskošek-Čukalov Ida J.

    2005-01-01

    Full Text Available Immobilized cell technology (ICT has been attracting continual attention in the brewing industry over the past 30 years. Some of the reasons are: faster fermentation rates and increased volumetric productivity, compared to those of traditional beer production based on freely suspended cells, as well as the possibility of continuous operation. Nowadays, ICT technology is well established in secondary fermentation and alcohol- free and low-alcohol beer production. In main fermentation, the situation is more complex and this process is still under scrutiny on both the lab and pilot levels. The paper outlines the most important ICT processes developed for beer brewing and provides an overview of carrier materials, bioreactor design and examples of their industrial applications, as well as some recent results obtained by our research group. We investigated the possible applications of polyvinyl alcohol in the form of LentiKats®, as a potential porous matrices carrier for beer fermentation. Given are the results of growth studies of immobilized brewer's yeast Saccharomyces uvarum and the kinetic parameters obtained by using alginate microbeads with immobilized yeast cells and suspension of yeast cells as controls. The results indicate that the immobilization procedure in LentiKat® carriers has a negligible effect on cell viability and growth. The apparent specific growth rate of cells released in medium was comparable to that of freely suspended cells, implying preserved cell vitality. A series of batch fermentations performed in shaken flasks and an air-lift bioreactor indicated that the immobilized cells retained high fermentation activity. The full attenuation in green beer was reached after 48 hours in shaken flasks and less than 24 hours of fermentation in gas-lift bioreactors.

  2. Current concepts, classification, and results in short stem hip arthroplasty.

    Science.gov (United States)

    Falez, Francesco; Casella, Filippo; Papalia, Matteo

    2015-03-01

    Various short hip stems have been introduced with differing implant concepts of femoral fixation and implant length. There is a lack of proper classification for short hip stems, with a clear and accepted definition for implant length and extent of bone preservation in the metaphyseal and diaphyseal femur. This study analyzed the length of short hip stems. Stems were divided into collum, partial collum, and trochanter-sparing implants. An additional category was added, trochanter harming, which was defined as interruption of the circumferential integrity of the femoral neck. For all of the femoral components described, the designs were compared, excluding stems with insufficient clinical data. The 15 finally selected stems were classified as collum (1 stem), partial collum (7 stems), trochanter sparing (4 stems), and trochanter harming (3 stems). Mid-term results (>5 years of follow-up) were available for only 3 designs in the partial collum group. Taking into account the results of short-term studies (<5 years of follow-up), the femoral revision rate per 100 observed component years was <1 for most total hip arthroplasties. However, the studies varied greatly regarding level of significance, and short hip stems without published results are available commercially. Short hip stems cannot be circumscribed by a simple length limit. For some designs, clinical data collected from large patient cohorts showed a survivorship comparable to traditional stems. In cases that must be revised, this often can be performed with a conventional primary stem, fulfilling the promise to preserve bone for potential future revisions in younger patients.

  3. New results on inclusive nu Fe charged current interactions

    CERN Document Server

    Abramowicz, H; De Groot, J G H; Dydak, F; Eisele, F; Flottmann, T; Geweniger, C; Guyot, C; He, J T; Klasen, H; Kleinknecht, K; Knobloch, J; Królikowski, J; Lierl, H; May, J; Merlo, J P; Palazzi, P; Para, A; Peyaud, B; Pszola, B; Rander, J; Ranjard, F; Rothberg, J E; Ruan, T Z; Schlatter, W D; Schuller, J P; Steinberger, J; Tittel, K; Turlay, René; von Rüden, Wolfgang; Wahl, H; Willutzki, H J; Wotschack, J; Wu, W M

    1981-01-01

    Based on 60000(25000) nu ( nu ) events obtained recently in the CERN 200 GeV narrow band neutrino beam, the authors present new results on the nucleon structure functions F/sub 2/(x, Q/sup 2/) and xF/sub 3/(x, Q/sup 2/) and on the Callan Gross relation. The observed scaling violations of F/sub 2/ and xF/sub 3/ are interpreted in terms of QCD. The strong coupling constant alpha /sub s/ is measured in agreement with the QCD predicted behaviour. (8 refs).

  4. Stemless shoulder arthroplasty-current results and designs.

    Science.gov (United States)

    Churchill, R Sean; Athwal, George S

    2016-03-01

    Stemless shoulder arthroplasty was originally introduced in 2004 by a single manufacturer. Now, over a decade later, numerous designs are available outside the USA, but as yet, only one implant has been cleared by the Food and Drug Administration (FDA) and is available for use within the USA. Often referred to as "canal sparing," these implants are designed for metaphyseal fixation to minimize humeral bone removal, avoid intraoperative and postoperative humeral fracture complications, and to decrease morbidity associated with revision operations. Recently, the second generation of stemless arthroplasty, a convertible implant allowing use in either anatomic or reverse arthroplasty configuration, was released for use outside the USA. This paper will review the available designs, reported results, and raise potential concerns for this emerging technology.

  5. Wave-current interactions: model development and preliminary results

    Science.gov (United States)

    Mayet, Clement; Lyard, Florent; Ardhuin, Fabrice

    2013-04-01

    The coastal area concentrates many uses that require integrated management based on diagnostic and predictive tools to understand and anticipate the future of pollution from land or sea, and learn more about natural hazards at sea or activity on the coast. The realistic modelling of coastal hydrodynamics needs to take into account various processes which interact, including tides, surges, and sea state (Wolf [2008]). These processes act at different spatial scales. Unstructured-grid models have shown the ability to satisfy these needs, given that a good mesh resolution criterion is used. We worked on adding a sea state forcing in a hydrodynamic circulation model. The sea state model is the unstructured version of WAVEWATCH III c (Tolman [2008]) (which version is developed at IFREMER, Brest (Ardhuin et al. [2010]) ), and the hydrodynamic model is the 2D barotropic module of the unstructured-grid finite element model T-UGOm (Le Bars et al. [2010]). We chose to use the radiation stress approach (Longuet-Higgins and Stewart [1964]) to represent the effect of surface waves (wind waves and swell) in the barotropic model, as previously done by Mastenbroek et al. [1993]and others. We present here some validation of the model against academic cases : a 2D plane beach (Haas and Warner [2009]) and a simple bathymetric step with analytic solution for waves (Ardhuin et al. [2008]). In a second part we present realistic application in the Ushant Sea during extreme event. References Ardhuin, F., N. Rascle, and K. Belibassakis, Explicit wave-averaged primitive equations using a generalized Lagrangian mean, Ocean Modelling, 20 (1), 35-60, doi:10.1016/j.ocemod.2007.07.001, 2008. Ardhuin, F., et al., Semiempirical Dissipation Source Functions for Ocean Waves. Part I: Definition, Calibration, and Validation, J. Phys. Oceanogr., 40 (9), 1917-1941, doi:10.1175/2010JPO4324.1, 2010. Haas, K. A., and J. C. Warner, Comparing a quasi-3D to a full 3D nearshore circulation model: SHORECIRC and

  6. Deep penetrating eddy current for copper canister inspection. Main results

    Energy Technology Data Exchange (ETDEWEB)

    Tadeusz Stepinski [TSonic, Uppsala (Sweden)

    2004-02-01

    The aim of this project was to optimize the detection and characterization of deep flaws (voids) in copper plates. Two types of voids were investigated and compared: circular and rectangular. The circular voids had the form of cylindrical cavities while the rectangular ones were cavities with a rectangular cross section. All probes were of the same type, transmit-receive transducers with four pick-ups connected in a double differential configuration. Comparison of the EC responses to circular and rectangular voids obtained using the MDF12 probe has shown that both types of voids can be characterized using phase and amplitude of their responses in the complex impedance plane. Phase of the response in the impedance plane appeared to be a reliable measure of void depth. Phase dependence on the void depth is linear (which agrees with the theory) and its slope is approx -37 deg/mm. Magnitude of the EC response contains information on the void size provided that the void depth is known. It has been shown that magnitude of the EC responses is correlated to the lengths of the rectangular voids and hole diameter, this is, similar lengths and diameters result in similar response magnitudes. It should be noted, however, that multi-differential MDF probes generate responses with different shapes for circular and rectangular voids. First, shapes of the MDF probe responses in the impedance plane depend on the probe's orientation with respect to scanning direction. Second, they also depend upon the direction of scanning with respect to the void orientation. The measurements presented in this report were performed for the probe axis aligned along with the scanning direction and, in case of rectangular voids, for scanning direction along the void lengths. Comparison of the responses obtained from flat bottom holes in copper material taken from different canister parts has not shown any essential differences between the material samples. Conductivity measurement performed using

  7. 75 FR 69470 - Tele Atlas North America, Inc., Currently Doing Business as Tom Tom Including Off-Site Workers...

    Science.gov (United States)

    2010-11-12

    ... Employment and Training Administration Tele Atlas North America, Inc., Currently Doing Business as Tom Tom... Doing Business as Tom Tom, Concord, MA; Tele Atlas North America, Inc. Currently Doing Business as Tom Tom, Detroit, MI; Tele Atlas North America, Inc. Currently Doing Business as Tom Tom, Redwood, CA...

  8. A mechanism for the dynamo terms to sustain closed-flux current, including helicity balance, by driving current which crosses the magnetic field

    Energy Technology Data Exchange (ETDEWEB)

    Jarboe, T. R.; Nelson, B. A.; Sutherland, D. A. [University of Washington, Seattle, Washington 98195 (United States)

    2015-07-15

    An analysis of imposed dynamo current drive (IDCD) [T.R. Jarboe et al., Nucl. Fusion 52 083017 (2012)] reveals: (a) current drive on closed flux surfaces seems possible without relaxation, reconnection, or other flux-surface-breaking large events; (b) the scale size of the key physics may be smaller than is often computationally resolved; (c) helicity can be sustained across closed flux; and (d) IDCD current drive is parallel to the current which crosses the magnetic field to produce the current driving force. In addition to agreeing with spheromak data, IDCD agrees with selected tokamak data.

  9. Psychological factors, including alexithymia, in the prediction of cardiovascular risk in HIV infected patients: results of a cohort study.

    Directory of Open Access Journals (Sweden)

    Giustino Parruti

    Full Text Available BACKGROUND: Psychological factors are known predictors of cardiovascular disease in many clinical settings, but data are lacking for HIV infection. We carried out a prospective cohort study to evaluate potential psychological predictors of preclinical and clinical vascular disease in HIV patients. METHODOLOGY/PRINCIPAL FINDINGS: HIV patients were consecutively enrolled. Demographics, viral and immune parameters and traditional cardiovascular predictors were considered; Intima-Media Thickness (c-IMT, continuous measure and Carotid Plaques (CPs, focal thickening ≥1.5 mm were investigated by B-mode ultrasonography; depressive symptoms by the Beck Depression Inventory (BDI-II, Type D personality (Distressed Personality or Type D by the DS14, alexithymia by the Toronto Alexithymia Scale (TAS-20. Vascular outcomes included transient ischemic attacks or stroke, acute coronary syndrome, myocardial or other organ infarction. We enrolled 232 HIV subjects, 73.9% males, aged 44.5±9.9 y, 38.2% with AIDS diagnosis, 18.3% untreated. Mean Nadir CD4 T-cell counts were 237.5±186.2/mmc. Of them, 224 (96.5% attended IMT measurements; 201 (86.6% attended both IMT assessment and psychological profiling. Mean follow-up was 782±308 days. Fifty-nine patients (29.4% had CPs at baseline. Nineteen patients (9.5% had ≥1 vascular event; 12 (6.0% died due to such events (n = 4 or any cause. At baseline cross-sectional multivariate analysis, increasing age, total cholesterol, current smoking and Alexithymia score≥50 were significantly associated with both increased cIMT (linear regression and CPs (logistic regression. At follow-up analysis, log-rank tests and Cox's regression revealed that only older age (p = 0.001, current smoking (p = 0.019 and alexithymia score≥50 (p = 0.013 were independently associated with vascular events. CONCLUSIONS/SIGNIFICANCE: In HIV-infected subjects, the Alexithymic trait emerges as a strong predictor of increased IMT, presence of CPs

  10. Results of Current Density Distribution Mapping in PEM Fuel Cells Dependent on Operation Parameters

    Directory of Open Access Journals (Sweden)

    Zbigniew A. Styczynski

    2013-07-01

    Full Text Available This paper presents in situ measurements of a newly developed current density measurement system for proton exchange membrane fuel cells (PEMFC. While the functional principle and technical evaluation of the measurement system were presented in a previous paper, this paper analyzes the influence of various operation parameters, including multiple start-stop operation, at the anode, cathode and cooling locations on the distribution and long-term development of the current density. The system was operated for 500 h over two years with long periods of inactivity between measurements. The measurement results are evaluated and provide additional information on how to optimize the operation modes of fuel cells, including the start and stop of such systems as well as the water balance.

  11. Non-linear Simulations of MHD Instabilities in Tokamaks Including Eddy Current Effects and Perspectives for the Extension to Halo Currents

    CERN Document Server

    Hoelzl, M; Merkel, P; Atanasiu, C; Lackner, K; Nardon, E; Aleynikova, K; Liu, F; Strumberger, E; McAdams, R; Chapman, I; Fil, A

    2014-01-01

    The dynamics of large scale plasma instabilities can strongly be influenced by the mutual interaction with currents flowing in conducting vessel structures. Especially eddy currents caused by time-varying magnetic perturbations and halo currents flowing directly from the plasma into the walls are important. The relevance of a resistive wall model is directly evident for Resistive Wall Modes (RWMs) or Vertical Displacement Events (VDEs). However, also the linear and non-linear properties of most other large-scale instabilities may be influenced significantly by the interaction with currents in conducting structures near the plasma. The understanding of halo currents arising during disruptions and VDEs, which are a serious concern for ITER as they may lead to strong asymmetric forces on vessel structures, could also benefit strongly from these non-linear modeling capabilities. Modeling the plasma dynamics and its interaction with wall currents requires solving the magneto-hydrodynamic (MHD) equations in realist...

  12. 78 FR 75560 - Green Current Solutions, LLC; Supplemental Notice That Initial Market-Based Rate Filing Includes...

    Science.gov (United States)

    2013-12-12

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Green Current Solutions, LLC; Supplemental Notice That Initial Market-Based... above-referenced proceeding, of Green Current Solutions, LLC's application for market-based...

  13. Should the current DSM-IV-TR definition for PTSD be expanded to include serial and multiple microtraumas as aetiologies?

    Science.gov (United States)

    Seides, R

    2010-10-01

    Post-traumatic stress disorder (PTSD) is an anxiety disorder that develops from events that are interpreted as traumatic. It may be secondary to witnessing trauma to someone close, an event that threatens one's life or childhood sexual trauma. Resultant feelings can be fear, helplessness or horror. Thresholds at which traumatic events cause PTSD, the individual's coping ability and support systems help determine occurrence and severity of symptoms. According to DSM-IV-TR (DSM) definition, PTSD can occur after childhood sexual abuse or a single trauma threatening life or safety. However, it is becoming clearer that symptoms of PTSD can arise from multiple less severe traumas ('microtraumas'), which can be a consequence of a history of longstanding emotional neglect, humiliation or inaccurate attribution of blame. The DSM should consider modifying the criteria to include multiple microtraumas that can lead to PTSD symptoms and may even be more destructive to psychological health.

  14. Preferences Regarding Return of Genomic Results to Relatives of Research Participants, Including after Participant Death: Empirical Results from a Cancer Biobank.

    Science.gov (United States)

    Breitkopf, Carmen Radecki; Petersen, Gloria M; Wolf, Susan M; Chaffee, Kari G; Robinson, Marguerite E; Gordon, Deborah R; Lindor, Noralane M; Koenig, Barbara A

    2015-01-01

    Data are lacking with regard to participants' perspectives on return of genetic research results to relatives, including after the participant's death. This paper reports descriptive results from 3,630 survey respondents: 464 participants in a pancreatic cancer biobank, 1,439 family registry participants, and 1,727 healthy individuals. Our findings indicate that most participants would feel obligated to share their results with blood relatives while alive and would want results to be shared with relatives after their death.

  15. Test result communication in primary care: a survey of current practice.

    Science.gov (United States)

    Litchfield, Ian; Bentham, Louise; Lilford, Richard; McManus, Richard J; Hill, Ann; Greenfield, Sheila

    2015-11-01

    The number of blood tests ordered in primary care continues to increase and the timely and appropriate communication of results remains essential. However, the testing and result communication process includes a number of participants in a variety of settings and is both complicated to manage and vulnerable to human error. In the UK, guidelines for the process are absent and research in this area is surprisingly scarce; so before we can begin to address potential areas of weakness there is a need to more precisely understand the strengths and weaknesses of current systems used by general practices and testing facilities. We conducted a telephone survey of practices across England to determine the methods of managing the testing and result communication process. In order to gain insight into the perspectives from staff at a large hospital laboratory we conducted paired interviews with senior managers, which we used to inform a service blueprint demonstrating the interaction between practices and laboratories and identifying potential sources of delay and failure. Staff at 80% of practices reported that the default method for communicating normal results required patients to telephone the practice and 40% of practices required that patients also call for abnormal results. Over 80% had no fail-safe system for ensuring that results had been returned to the practice from laboratories; practices would otherwise only be aware that results were missing or delayed when patients requested results. Persistent sources of missing results were identified by laboratory staff and included sample handling, misidentification of samples and the inefficient system for collating and resending misdirected results. The success of the current system relies on patients both to retrieve results and in so doing alert staff to missing and delayed results. Practices appear slow to adopt available technological solutions despite their potential for reducing the impact of recurring errors in the

  16. Quality metrics currently used in academic radiology departments: results of the QUALMET survey.

    Science.gov (United States)

    Walker, Eric A; Petscavage-Thomas, Jonelle M; Fotos, Joseph S; Bruno, Michael A

    2017-03-01

    We present the results of the 2015 quality metrics (QUALMET) survey, which was designed to assess the commonalities and variability of selected quality and productivity metrics currently employed by a large sample of academic radiology departments representing all regions in the USA. The survey of key radiology metrics was distributed in March-April of 2015 via personal e-mail to 112 academic radiology departments. There was a 34.8% institutional response rate. We found that most academic departments of radiology commonly utilize metrics of hand hygiene, report turn around time (RTAT), relative value unit (RVU) productivity, patient satisfaction and participation in peer review. RTAT targets were found to vary widely. The implementation of radiology peer review and the variety of ways in which peer review results are used within academic radiology departments, the use of clinical decision support tools and requirements for radiologist participation in Maintenance of Certification also varied. Policies for hand hygiene and critical results communication were very similar across all institutions reporting, and most departments utilized some form of missed case/difficult case conference as part of their quality and safety programme, as well as some form of periodic radiologist performance reviews. Results of the QUALMET survey suggest many similarities in tracking and utilization of the selected quality and productivity metrics included in our survey. Use of quality indicators is not a fully standardized process among academic radiology departments. Advances in knowledge: This article examines the current quality and productivity metrics in academic radiology.

  17. Dynamic modeling of slow-light in a semiconductor optical amplifier including the effects of forced coherent population oscillations by bias current modulation

    Science.gov (United States)

    Connelly, M. J.

    2014-05-01

    The slow light effect in SOAs has many applications in microwave photonics such as phase shifting and filtering. Models are needed to predict slow light in SOAs and its dependence on the bias current, optical power and modulation index. In this paper we predict the slow light characteristics of a tensile-strained SOA by using a detailed time-domain model. The model includes full band-structure based calculations of the material gain, bimolecular recombination and spontaneous emission, a carrier density rate equation and travelling wave equations for the input signal and amplified spontaneous emission. The slow light effect is caused by coherent population oscillations, whereby beating between the spectral components of an amplitude modulated lightwave causes carrier density oscillations at the beat frequency, leading to changes in the group velocity. The resulting beat signal at the SOA output after photodetection, is phase shifted relative to the SOA input beat signal. The phase shift can be adjusted by controlling the optical power and bias current. However the beat signal gain is low at low frequencies, leading to a poor beat signal output signal-to-noise ratio. If the optical input and SOA drive current are simultaneously modulated, this leads to forced population oscillations that greatly enhance the low frequency beat signal gain. The model is used to determine the improvement in gain and phase response and its dependency on the optical power, bias current and modulation index. Model predictions show good agreement with experimental trends reported in the literature.

  18. Comparison on Heat of Hydration between Current Concrete for NPP and High Fluidity Concrete including Pozzolan Powders

    Energy Technology Data Exchange (ETDEWEB)

    Noh, Jea Myoung; Cho, Myung Sug [KEPCO Research Institute, Daejeon (Korea, Republic of)

    2010-10-15

    Nuclear power plant (NPP) concrete structures are exposed to many construction factors that lower the quality of concrete due to densely packed reinforcements and heat of hydration since they are mostly constructed with mass concrete. The concrete currently being used in Korean NPPs is mixed with Type I cement and fly ash. However, there is a demand to improve the performance of concrete with reduced heat of hydration and superior constructability. Many advantages such as improving workability and durability of concrete and decreasing heat of hydration are introduced by replacing cement with pozzolan binders. Therefore, the manufacturing possibility of high fluidity concrete should be investigated through applying multi-component powders blended with pozzolan binders to the concrete structure of NPPs, while the researches on properties, characteristic of hydration, durability and long-term behavior of high fluidity concrete using multi-component cement should be carried out. High fluidity concrete which is made using portland cement and pozzlonan powders such as fly ash and blast furnace slag has better properties on heat of hydration than the concrete currently in use for NPPs

  19. Carbon Dioxide Sequestration by Direct Mineral Carbonation: Results from Recent Studies and Current Status

    Energy Technology Data Exchange (ETDEWEB)

    O' Connor, William K.; Dahlin, David C.; Nilsen, David N.; Rush, G.E.; Walters, Richard P.; Turner, Paul C.

    2001-01-01

    Direct mineral carbonation has been investigated as a process to convert gaseous CO2 into a geologically stable, solid final form. The process utilizes a solution of sodium bicarbonate (NaHCO3), sodium chloride (NaCl), and water, mixed with a mineral reactant, such as olivine (Mg2SiO4) or serpentine [Mg3Si2O5(OH)4]. Carbon dioxide is dissolved into this slurry, by diffusion through the surface and gas dispersion within the aqueous phase. The process includes dissolution of the mineral and precipitation of magnesium carbonate (MgCO3) in a single unit operation. Optimum results have been achieved using heat pretreated serpentine feed material, with a surface area of roughly 19 m2 per gram, and high partial pressure of CO2 (PCO2). Specific conditions include: 155?C; PCO2=185 atm; 15% solids. Under these conditions, 78% stoichiometric conversion of the silicate to the carbonate was achieved in 30 minutes. Studies suggest that the mineral dissolution rate is primarily surface controlled, while the carbonate precipitation rate is primarily dependent on the bicarbonate concentration of the slurry. Current studies include further examination of the reaction pathways, and an evaluation of the resource potential for the magnesium silicate reactant, particularly olivine. Additional studies include the examination of various pretreatment options, the development of a continuous flow reactor, and an evaluation of the economic feasibility of the process.

  20. Assessing the Applicability of Currently Available Methods for Attributing Foodborne Disease to Sources, Including Food and Food Commodities

    DEFF Research Database (Denmark)

    Pires, Sara Monteiro

    2013-01-01

    Abstract A variety of approaches to attribute foodborne diseases to specific sources are available, including hazard occurrence analysis, epidemiological methods, intervention studies, and expert elicitations. The usefulness of each method to attribute disease caused by a foodborne hazard depends...... on the public health question being addressed, on the data requirements, on advantages and limitations of the method, and on the data availability of the country or region in question. Previous articles have described available methods for source attribution, but have focused only on foodborne microbiological...

  1. Quantifying the Earthquake Clustering that Independent Sources with Stationary Rates (as Included in Current Risk Models) Can Produce.

    Science.gov (United States)

    Fitzenz, D. D.; Nyst, M.; Apel, E. V.; Muir-Wood, R.

    2014-12-01

    The recent Canterbury earthquake sequence (CES) renewed public and academic awareness concerning the clustered nature of seismicity. Multiple event occurrence in short time and space intervals is reminiscent of aftershock sequences, but aftershock is a statistical definition, not a label one can give an earthquake in real-time. Aftershocks are defined collectively as what creates the Omori event rate decay after a large event or are defined as what is taken away as "dependent events" using a declustering method. It is noteworthy that depending on the declustering method used on the Canterbury earthquake sequence, the number of independent events varies a lot. This lack of unambiguous definition of aftershocks leads to the need to investigate the amount of clustering inherent in "declustered" risk models. This is the task we concentrate on in this contribution. We start from a background source model for the Canterbury region, in which 1) centroids of events of given magnitude are distributed using a latin-hypercube lattice, 2) following the range of preferential orientations determined from stress maps and focal mechanism, 3) with length determined using the local scaling relationship and 4) rates from a and b values derived from the declustered pre-2010 catalog. We then proceed to create tens of thousands of realizations of 6 to 20 year periods, and we define criteria to identify which successions of events in the region would be perceived as a sequence. Note that the spatial clustering expected is a lower end compared to a fully uniform distribution of events. Then we perform the same exercise with rates and b-values determined from the catalog including the CES. If the pre-2010 catalog was long (or rich) enough, then the computed "stationary" rates calculated from it would include the CES declustered events (by construction, regardless of the physical meaning of or relationship between those events). In regions of low seismicity rate (e.g., Canterbury before

  2. Assessing the applicability of currently available methods for attributing foodborne disease to sources, including food and food commodities.

    Science.gov (United States)

    Pires, Sara M

    2013-03-01

    A variety of approaches to attribute foodborne diseases to specific sources are available, including hazard occurrence analysis, epidemiological methods, intervention studies, and expert elicitations. The usefulness of each method to attribute disease caused by a foodborne hazard depends on the public health question being addressed, on the data requirements, on advantages and limitations of the method, and on the data availability of the country or region in question. Previous articles have described available methods for source attribution, but have focused only on foodborne microbiological hazards. These articles have described strengths and weaknesses of each method, but no guidance on how to choose the most appropriate tool to address different public health questions has thus far been provided. We reviewed available source attribution methods; assessed their applicability to attribute illness caused by enteric, parasitic, and chemical foodborne hazards to the responsible sources; and renamed some of the approaches. The main objective was to make recommendations on the most appropriate method(s) to attribute human disease caused by different foodborne hazards. We concluded that the proportion of disease that can be attributed to specific foods items or transmission routes may be estimated for the majority of the evaluated hazards by applying one or more of the source attribution methods assessed. It was also recognized that the use of source attribution methods may be limited to specific countries, reflecting the data availability.

  3. The analysis of the performance test results including correlation between the traits of this evaluation in crossbred gilts

    Directory of Open Access Journals (Sweden)

    Jerzy NOWACHOWICZ

    2012-12-01

    Full Text Available The aim of the paper was the analysis of the performance test results including correlation between the traits of this evaluation in crossbred gilts of Polish Large White (PLW and Polish Landrace (PL, conducted in years 2004-2008 in Poland in The Bydgoszcz Breeding Region. The subject of research was 51.802 crossbred gilts came from two crossing variants (where the sows’ breed was given in first position: PLW x PL and PL x PLW. The PLW x PL crossbred gilts in years 2004-2007 and in a total results summary from years 2004-2008 obtained higher performance test selection index value, thus had higher the breeding value regarding to the growth and slaughter traits as compared to the animals came from PL x PLW crossing variant. Within the space of 5 analysed years (2004-2008 the performance test selection index increased in the PLW x PL and PL x PLW crossbred gilts by 3.6 and 5.8 points, respectively. Thus the improvement of the breeding value of evaluated animals has been done. In all analysed years in the tested groups of crossbred gilts negative and statistically high significant correlations have been observed between the growth rate and the standardised body meat content of animals, which may show the unfavourable impact of the high growth rate on the meat content of pigs.

  4. Test results of 12/18 kA ReBCO coated conductor current leads

    Science.gov (United States)

    Kovalev, I. A.; Surin, M. I.; Naumov, A. V.; Novikov, M. S.; Novikov, S. I.; Ilin, A. A.; Polyakov, A. V.; Scherbakov, V. I.; Shutova, D. I.

    2017-07-01

    A pair of hybrid current leads (brass + stacked & soldered ReBCO tapes) rated for 12 kA in steady state and for up to 18 kA at pulsed over current conditions was designed, developed and tested at NRC ;Kurchatov Institute; (NRC ;KI;). During the experiment at LN2 temperature, the current leads (CLs) were successfully charged with 18 kA at 100 A/s ramp rate. To date, as far as we know, this is the highest current capacity achieved for 2G HTS current leads. The feasibility of ;stack-and-soldering technique; for 10 kA+ class coated conductor CLs for accelerators and fusion was demonstrated. This paper gives an overview of the leads design and presents the preliminary test results. Detailed studies of magnetic properties and current sharing process for the stacked and staggered HTS joints are also reported.

  5. MODARIA WG5: Towards a practical guidance for including uncertainties in the results of dose assessment of routine releases

    Energy Technology Data Exchange (ETDEWEB)

    Mora, Juan C. [Centro de Investigaciones Energeticas, Medioambientales y Tecnologicas - CIEMAT (Spain); Telleria, Diego [International Atomic Energy Agency - IAEA (Austria); Al Neaimi, Ahmed [Emirates Nuclear Energy Corporation - ENEC (United Arab Emirates); Blixt Buhr, Anna Ma [Vattenfall AB (Sweden); Bonchuk, Iurii [Radiation Protection Institute - RPI (Ukraine); Chouhan, Sohan [Atomic Energy of Canada Limited - AECL (Canada); Chyly, Pavol [SE-VYZ (Slovakia); Curti, Adriana R. [Autoridad Regulatoria Nuclear - ARN (Argentina); Da Costa, Dejanira [Instituto de Radioprotecao e Dosimetria - IRD (Brazil); Duran, Juraj [VUJE Inc (Slovakia); Galeriu, Dan [Horia Hulubei National Institute of Physics and Nuclear Engineering - IFIN-HH (Romania); Haegg, Ann- Christin; Lager, Charlotte [Swedish Radiation Safety Authority - SSM (Sweden); Heling, Rudie [Nuclear Research and Consultancy Group - NRG (Netherlands); Ivanis, Goran; Shen, Jige [Ecometrix Incorporated (Canada); Iosjpe, Mikhail [Norwegian Radiation Protection Authority - NRPA (Norway); Krajewski, Pawel M. [Central Laboratory for Radiological Protection - CLOR (Poland); Marang, Laura; Vermorel, Fabien [Electricite de France - EdF (France); Mourlon, Christophe [Institut de Radioprotection et de Surete Nucleaire - IRSN (France); Perez, Fabricio F. [Belgian Nuclear Research Centre - SCK (Belgium); Woodruffe, Andrew [Federal Authority for Nuclear Regulation - FANR (United Arab Emirates); Zorko, Benjamin [Jozef Stefan Institute (Slovenia)

    2014-07-01

    MODARIA (Modelling and Data for Radiological Impact Assessments) project was launched in 2012 with the aim of improving the capabilities in radiation dose assessment by means of acquisition of improved data for model testing, model testing and comparison, reaching consensus on modelling philosophies, approaches and parameter values, development of improved methods and exchange of information. The project focuses on areas where uncertainties remain in the predictive capability of environmental models, emphasizing in reducing associated uncertainties or developing new approaches to strengthen the evaluation of the radiological impact. Within MODARIA, four main areas were defined, one of them devoted to Uncertainty and Variability. In this area four working groups were included, Working Group 5 dealing with the 'uncertainty and variability analysis for assessments of radiological impacts arising from routine discharges of radionuclides'. Whether doses are estimated by using measurement data, by applying models, or through a combination of measurements and calculations, the variability and uncertainty contribute to a distribution of possible values. The degree of variability and uncertainty is represented by the shape and extent of that distribution. The main objective of WG5 is to explore how to consider uncertainties and variabilities in the results of assessment of doses in planned situations for controlling the impact of routine releases from radioactive and nuclear installations to the environment. The final aim is to produce guidance for the calculation of uncertainties in these exposure situations and for the presentation of such results to the different stakeholders. To achieve that objective the main tasks identified were: to find tools and methods for uncertainty and variability analysis applicable to dose assessments in routine radioactive discharges, to define scenarios where information on uncertainty and variability of parameters is available

  6. First experimental results with the Current Limit Avoidance System at the JET tokamak

    Energy Technology Data Exchange (ETDEWEB)

    De Tommasi, G. [Associazione EURATOM-ENEA-CREATE, Università di Napoli Federico II, Via Claudio 21, 80125 Napoli (Italy); Galeani, S. [Dipartimento di Informatica, Sistemi e Produzione, Università di Roma, Tor Vergata, Rome (Italy); Jachmich, S. [Association EURATOM-Belgian State, Koninklijke Militaire School - Ecole Royale Militaire, B-1000 Brussels (Belgium); Joffrin, E. [IRFM-CEA, Centre de Cadarache, 13108 Saint-paul-lez-Durance (France); Lennholm, M. [EFDA Close Support Unit, Culham Science Centre, OX14 3DB Abingdon (United Kingdom); European Commission, B-1049 Brussels (Belgium); Lomas, P.J. [Euratom-CCFE, Culham Science Centre, OX14 3DB Abingdon (United Kingdom); Neto, A.C. [Associazione EURATOM-IST, Instituto de Plasmas e Fusao Nuclear, IST, 1049-001 Lisboa (Portugal); Maviglia, F. [Associazione EURATOM-ENEA-CREATE, Via Claudio 21, 80125 Napoli (Italy); McCullen, P. [Euratom-CCFE, Culham Science Centre, OX14 3DB Abingdon (United Kingdom); Pironti, A. [Associazione EURATOM-ENEA-CREATE, Università di Napoli Federico II, Via Claudio 21, 80125 Napoli (Italy); Rimini, F.G. [Euratom-CCFE, Culham Science Centre, OX14 3DB Abingdon (United Kingdom); Sips, A.C.C. [European Commission, B-1049 Brussels (Belgium); Varano, G.; Vitelli, R. [Dipartimento di Informatica, Sistemi e Produzione, Università di Roma, Tor Vergata, Rome (Italy); Zaccarian, L. [CNRS, LAAS, 7 Avenue du Colonel Roche, F-31400 Toulouse (France); Universitè de Toulouse, LAAS, F-31400 Toulouse (France)

    2013-06-15

    The Current Limit Avoidance System (CLA) has been recently deployed at the JET tokamak to avoid current saturations in the poloidal field (PF) coils when the eXtreme Shape Controller is used to control the plasma shape. In order to cope with the current saturation limits, the CLA exploits the redundancy of the PF coils system to automatically obtain almost the same plasma shape using a different combination of currents in the PF coils. In the presence of disturbances it tries to avoid the current saturations by relaxing the constraints on the plasma shape control. The CLA system has been successfully implemented on the JET tokamak and fully commissioned in 2011. This paper presents the first experimental results achieved in 2011–2012 during the restart and the ITER-like wall campaigns at JET.

  7. Test results of the 18 kA EDIPO HTS current leads

    Energy Technology Data Exchange (ETDEWEB)

    Wesche, Rainer, E-mail: rainer.wesche@psi.ch [Ecole Polytechnique Federale de Lausanne (EPFL), Centre de Recherches en Physique des Plasmas (CRPP), Association Euratom - Confederation Suisse, 5232 Villigen PSI (Switzerland); Bagnasco, Maurizio; Bruzzone, Pierluigi; Felder, Roland; Guetg, Marc; Holenstein, Manuel; Jenni, Markus; March, Stephen; Roth, Felix; Vogel, Martin [Ecole Polytechnique Federale de Lausanne (EPFL), Centre de Recherches en Physique des Plasmas (CRPP), Association Euratom - Confederation Suisse, 5232 Villigen PSI (Switzerland)

    2011-10-15

    For the new test facility EDIPO (European DIPOle), to be hosted by CRPP, two 18 kA HTS current leads were manufactured and successfully tested. The HTS module, made of AgMgAu/Bi-2223 tapes, is cooled only by heat conduction to the cold end, while the copper part is cooled by forced flow helium gas. The current leads were tested at low voltage up to the maximum current of 18 kA. The helium mass flow rates required for stable operation at various currents were determined. In addition to the steady state operation, the transient behavior in the case of a loss of flow was studied experimentally. The test results provide an estimate of the operational limits of the EDIPO HTS current leads.

  8. Including information about comorbidity in estimates of disease burden: Results from the WHO World Mental Health Surveys

    Science.gov (United States)

    Alonso, Jordi; Vilagut, Gemma; Chatterji, Somnath; Heeringa, Steven; Schoenbaum, Michael; Üstün, T. Bedirhan; Rojas-Farreras, Sonia; Angermeyer, Matthias; Bromet, Evelyn; Bruffaerts, Ronny; de Girolamo, Giovanni; Gureje, Oye; Haro, Josep Maria; Karam, Aimee N.; Kovess, Viviane; Levinson, Daphna; Liu, Zhaorui; Mora, Maria Elena Medina; Ormel, J.; Posada-Villa, Jose; Uda, Hidenori; Kessler, Ronald C.

    2010-01-01

    Background The methodology commonly used to estimate disease burden, featuring ratings of severity of individual conditions, has been criticized for ignoring comorbidity. A methodology that addresses this problem is proposed and illustrated here with data from the WHO World Mental Health Surveys. Although the analysis is based on self-reports about one’s own conditions in a community survey, the logic applies equally well to analysis of hypothetical vignettes describing comorbid condition profiles. Methods Face-to-face interviews in 13 countries (six developing, nine developed; n = 31,067; response rate = 69.6%) assessed 10 classes of chronic physical and 9 of mental conditions. A visual analog scale (VAS) was used to assess overall perceived health. Multiple regression analysis with interactions for comorbidity was used to estimate associations of conditions with VAS. Simulation was used to estimate condition-specific effects. Results The best-fitting model included condition main effects and interactions of types by numbers of conditions. Neurological conditions, insomnia, and major depression were rated most severe. Adjustment for comorbidity reduced condition-specific estimates with substantial between-condition variation (.24–.70 ratios of condition-specific estimates with and without adjustment for comorbidity). The societal-level burden rankings were quite different from the individual-level rankings, with the highest societal-level rankings associated with conditions having high prevalence rather than high individual-level severity. Conclusions Plausible estimates of disorder-specific effects on VAS can be obtained using methods that adjust for comorbidity. These adjustments substantially influence condition-specific ratings. PMID:20553636

  9. MEASURING RESULTS NUMERAL TREATMENT OF IMPULSIVE CURRENTS BY MEANS OF ROGOVSKY BELT APPLICATION

    Directory of Open Access Journals (Sweden)

    U. Batygin

    2009-01-01

    Full Text Available The technique of numerical processing of measurement results of pulse currents by means of Rogovsky belt application is offered in the given work. It is shown that at measurement of signals by digital oscillographs and further numerical transformation of target signals, the possibilities of Rogovsky belt without the application of additional devices that in turn allows to define parameters of pulse currents with any peak-time characteristics essentially expand.

  10. Prior doctor shopping resulting from differential treatment correlates with differences in current patient-provider relationships.

    Science.gov (United States)

    Gudzune, Kimberly A; Bennett, Wendy L; Cooper, Lisa A; Clark, Jeanne M; Bleich, Sara N

    2014-09-01

    To determine the prevalence of doctor shopping resulting from differential treatment and to examine associations between this shopping and current primary care relationships. In 2012, a national internet-based survey of 600 adults receiving primary care in the past year with a BMI ≥ 25 kg/m(2) was conducted. Our independent variable was "switching doctors because I felt treated differently because of my weight." Logistic regression models to examine the association of prior doctor shopping with characteristics of current primary care relationships: duration, trust in primary care provider (PCP), and perceived PCP weight-related judgment, adjusted for patient factors were used. Overall, 13% of adults with overweight/obesity reported previously doctor shopping resulting from differential treatment. Prior shoppers were more likely to report shorter durations of their current relationships [73% vs. 52%; p = 0.01] or perceive that their current PCP judged them because of their weight [74% vs. 11%; p shop resulting from perceived differential treatment. These prior negative experiences have no association with trust in current relationships, but our results suggest that patients may remain sensitive to provider weight bias. © 2014 The Obesity Society.

  11. One common structural peculiarity of the Solar system bodies including the star, planets, satellites and resulting from their globes rotation

    Science.gov (United States)

    Kochemasov, , G. G.

    2008-09-01

    Often observed a sensible difference in appearance and structure between tropical and extra-tropical zones of various heavenly bodies including rocky and gas planets, satellites and Sun compels to look for a common reason of such phenomenon. All bodies rotate and their spherical shape makes zones at different latitudes to have differing angular momenta as a distance to the rotation axis diminishes gradually from the equator to the poles (this is felt particularly when one launches rockets into space -preferable more cheap launches are from the equatorial regions - Kourou is better than Baikonur). One of remarkable changes occurs at tropics. As a single rotating planetary body tends to have angular momenta of its tectonic blocks equilibrated it starts mechanisms leveling this basic physical property. At tropical zones (bulged also due to the rotation ellipsoid) the outer shell - crust as a consequence tends to be destroyed, sunk, subsided and shrunk; a density of crust material changes; the atmosphere reacts changing chemistry and structure; in terrestrial anthroposphere man looses its mass and stature. But according to the Le Chatelier rule mechanisms with an opposing tendency also begin to act. At Earth the wide planetary long tropical zone is marked by destruction of the crust. It is demonstrated by development of numerous islands of the Malay Archipelago (the Sunda Isls., Maluku Isls, Philippines) between the Southeastern Asia and Australia. In Africa and South America huge depressions of the Congo and Amazon Rivers develops where the Archean crust is subsided to depths of more than 2 km. In the Pacific along the equator numerous islands of Micronesia occur. Subsidence of the basaltic oceanic crust is followed by an intensive folding and faulting of basalt and sedimentary layers (Fig. 1) as a larger mass must be held by a smaller space (a planetary radius is diminished). The central Atlantic is very demonstrative in this sense suffering huge transform fault

  12. Stability, Singularities and Mass Thresholds in Child Universe Production: a concise survey including some recent results and prospects

    OpenAIRE

    Ansoldi, Stefano; Guendelman, Eduardo I.; Shilon, Idan

    2007-01-01

    Comment: 19 pages LaTeX, including 68 references; to appear in the Proceedings of "BH2, Dynamics and Thermodynamics of Blackholes and Naked Singularities", May 10-12 2007, Milano, Italy; conference website: http://www.mate.polimi.it/bh2

  13. Combination formoterol and budesonide as maintenance and reliever therapy versus current best practice (including inhaled steroid maintenance), for chronic asthma in adults and children.

    Science.gov (United States)

    Cates, Christopher J; Karner, Charlotta

    2013-04-30

    Traditionally inhaled treatment for asthma has used separate preventer and reliever therapies. The combination of formoterol and budesonide in one inhaler has made possible a single inhaler for both prevention and relief of symptoms (single inhaler therapy or SiT). To assess the efficacy and safety of budesonide and formoterol in a single inhaler for maintenance and reliever therapy in asthma compared with maintenance with inhaled corticosteroids (ICS) (alone or as part of current best practice) and any reliever therapy. We searched the Cochrane Airways Group trials register in February 2013. Parallel, randomised controlled trials of 12 weeks or longer in adults and children with chronic asthma. Studies had to assess the combination of formoterol and budesonide as SiT, against a control group that received inhaled steroids and a separate reliever inhaler. We used standard methodological procedures expected by The Cochrane Collaboration. We included 13 trials involving 13,152 adults and one of the trials also involved 224 children (which have been separately reported). All studies were sponsored by the manufacturer of the SiT inhaler. We considered the nine studies assessing SiT against best practice to be at a low risk of selection bias, but a high risk of detection bias as they were unblinded.In adults whose asthma was not well-controlled on ICS, the reduction in hospital admission with SiT did not reach statistical significance (Peto odds ratio (OR) 0.81; 95% confidence interval (CI) 0.45 to 1.44, eight trials, N = 8841, low quality evidence due to risk of detection bias in open studies and imprecision). The rates of hospital admission were low; for every 1000 people treated with current best practice six would experience a hospital admission over six months compared with between three and eight treated with SiT. The odds of experiencing exacerbations needing treatment with oral steroids were lower with SiT compared with control (OR 0.83; 95% CI 0.70 to 0

  14. Including capabilities of local actors in regional economic development: Empirical results of local seaweed industries in Sulawesi

    Directory of Open Access Journals (Sweden)

    Mark T.J. Vredegoor

    2013-10-01

    Full Text Available Stimson, et al. (2009 developed one of the most relevant and well known model for Regional Eco- nomic Development. This model covers the most important factors related to economic develop- ment question. However, this model excludes the social components of development. Local com- munity should be included in terms of the development of a region. This paper introduced to the Stimson model “Skills” and “Knowledge” at the individual level for local actors indicating the ca- pabilities at the individual level and introduced “Human Coordination” for the capabilities at the collective level. In our empirical research we looked at the Indonesian seaweed market with a spe- cific focus on the region of Baubau. This region was chosen because there are hardly any economic developments. Furthermore this study focuses on the poorer community who are trying to improve their situation by the cultivation of Seaweed. Eighteen local informants was interviewed besides additional interviews of informants from educational and governmental institutions in the cities of Jakarta, Bandung and Yogyakarta. The informants selected had a direct or indirect relationship with the region of Baubau. With the support of the empirical data from this region we can confirm that it is worthwhile to include the local community in the model for regional economic develop- ment. The newly added variables: at the individual level; Skills and Knowledge and at the level of the collective: Human Coordination was supported by the empirical material. It is an indication that including the new variables can give regional economic an extra dimension. In this way we think that it becomes more explicit that “endogenous” means that the people, or variables closely related to them, should be more explicitly included in models trying to capture Regional Economic Develop- ment or rephrased as Local Economic Development

  15. Current treatment for venom-induced consumption coagulopathy resulting from snakebite.

    Directory of Open Access Journals (Sweden)

    Kalana Maduwage

    2014-10-01

    Full Text Available Venomous snakebite is considered the single most important cause of human injury from venomous animals worldwide. Coagulopathy is one of the commonest important systemic clinical syndromes and can be complicated by serious and life-threatening haemorrhage. Venom-induced consumption coagulopathy (VICC is the commonest coagulopathy resulting from snakebite and occurs in envenoming by Viperid snakes, certain elapids, including Australian elapids, and a few Colubrid (rear fang snakes. Procoagulant toxins activate the clotting pathway, causing a broad range of factor deficiencies depending on the particular procoagulant toxin in the snake venom. Diagnosis and monitoring of coagulopathy is problematic, particularly in resource-poor countries where further research is required to develop more reliable, cheap clotting tests. MEDLINE and EMBASE up to September 2013 were searched to identify clinical studies of snake envenoming with VICC. The UniPort database was searched for coagulant snake toxins. Despite preclinical studies demonstrating antivenom binding toxins (efficacy, there was less evidence to support clinical effectiveness of antivenom for VICC. There were no placebo-controlled trials of antivenom for VICC. There were 25 randomised comparative trials of antivenom for VICC, which compared two different antivenoms (ten studies, three different antivenoms (four, two or three different doses or repeat doses of antivenom (five, heparin treatment and antivenom (five, and intravenous immunoglobulin treatment and antivenom (one. There were 13 studies that compared two groups in which there was no randomisation, including studies with historical controls. There have been numerous observational studies of antivenom in VICC but with no comparison group. Most of the controlled trials were small, did not use the same method for assessing coagulopathy, varied the dose of antivenom, and did not provide complete details of the study design (primary outcomes

  16. Prolonged-release nicotinic acid for the management of dyslipidemia: an update including results from the NAUTILUS study

    Directory of Open Access Journals (Sweden)

    Anja Vogt

    2007-09-01

    Full Text Available Anja Vogt1, Ursula Kassner1, Ulrike Hostalek2, Elisabeth Steinhagen-Thiessen11Charite-Universitatsmedizin Berlin, Germany; 2Merck KGaA, Darmstadt, GermanyAbstract: Low HDL-cholesterol (<1.02 mmol/L [40 mg/dL] in men or <1.29 mmol/L [50 mg/dL] in women occurs in about one-third of European patients with dyslipidemia and is an independent cardiovascular risk factor. Simultaneous correction of low HDL-cholesterol and high totalcholesterol and LDL-cholesterol may provide reductions in cardiovascular morbidity and mortality beyond those possible with statins alone. Nicotinic acid (niacin in the US is the most effective means of increasing HDL-cholesterol available and has been shown to reduce cardiovascular event rates significantly. Niaspan® (prolonged-release nicotinic acid provides a convenient, once-daily means of administering nicotinic acid. Clinical studies with Niaspan® have demonstrated marked, long-term increases in HDL-cholesterol with additional useful benefits on triglycerides, LDLcholesterol, and lipid sub-profiles. The NAUTILUS study demonstrated the beneficial efficacy and tolerability profiles of Niaspan® in a usual-care setting. The most common side-effect of Niaspan® is flushing, which infrequently causes treatment discontinuation and which usually subsides over continued treatment. The ARBITER 2 and ARBITER 3 studies showed 1–2 years of treatment with Niaspan® plus a statin induced regression of atherosclerosis in patients with coronary artery disease. The effect of Niaspan®-statin treatment, relative to a statin alone, on clinical cardiovascular outcomes is currently under evaluation. Niaspan® represents a practical means of correcting low HDL-cholesterol, an independent risk factor for adverse cardiovascular outcomes.Keywords: prolonged-release nicotinic acid, Niaspan®, niacin, dyslipidemia, HDL-cholesterol cardiovascular risk

  17. Participation in a trauma-focused epidemiological investigation may result in sensitization for current health problems

    NARCIS (Netherlands)

    Verschuur, M.J.; Spinhoven, Ph.; van Emmerik, A.A.P.; Rosendaal, F.R.

    2008-01-01

    Objectives - Participation in health survey research may result in a worsening of self-assessed health status and enhanced service-use by increasing self-awareness of current health status. The present study investigated whether participation in a traumafocused epidemiological study sensitized parti

  18. Harmonic Analysis of Currents and Voltages Obtained in the Result of Computational Experiment

    Directory of Open Access Journals (Sweden)

    I. V. Novash

    2011-01-01

    Full Text Available The paper considers a methodology for execution of a harmonic analysis of current and voltage numerical values obtained in the result of a computational experiment and saved in an external data file. The harmonic analysis has been carried out in the Mathcad mathematical packet environment.

  19. Description of premixing with the MC3D code including molten jet behavior modeling. Comparison with FARO experimental results

    Energy Technology Data Exchange (ETDEWEB)

    Berthoud, G.; Crecy, F. de; Meignen, R.; Valette, M. [CEA-G, DRN/DTP/SMTH, 17 rue des Martyrs, 38054 Grenoble Cedex 9 (France)

    1998-01-01

    The premixing phase of a molten fuel-coolant interaction is studied by the way of mechanistic multidimensional calculation. Beside water and steam, corium droplet flow and continuous corium jet flow are calculated independent. The 4-field MC3D code and a detailed hot jet fragmentation model are presented. MC3D calculations are compared to the FARO L14 experiment results and are found to give satisfactory results; heat transfer and jet fragmentation models are still to be improved to predict better final debris size values. (author)

  20. Evolution of the Coronal Magnetic Configurations Including a Current-Carrying Flux Rope in Response to the Change in the Background Field

    CERN Document Server

    Wang, Hong-Juan; Gong, Jian-Cun; Lin, Jun

    2014-01-01

    We investigate equilibrium height of the flux rope, and its internal equilibrium in a realistic plasma environment by carrying out numerical simulations of the evolution of systems including a current-carrying flux rope. We find that the equilibrium height of the flux rope is approximately a power-law function of the relative strength of the background field. Our simulations indicate that the flux rope can escape more easily from a weaker background field. This further confirms the catastrophe in the magnetic configuration of interest can be triggered by decrease of strength of the background field. Our results show that it takes some time to reach internal equilibrium depending on the initial state of the flux rope. The plasma flow inside the flux rope due to the adjustment for the internal equilibrium of the flux rope remains small and does not last very long when the initial state of the flux rope commences from the stable branch of the theoretical equilibrium curve. This work also confirms the influence o...

  1. TANK INSPECTION NDE RESULTS FOR FISCAL YEAR 2007INCLUDING WASTE TANKS 35, 36, 37, 38 AND 15

    Energy Technology Data Exchange (ETDEWEB)

    Elder, J

    2007-09-27

    Ultrasonic (UT) nondestructive examinations (NDE) were performed on waste storage tanks 35, 36, 37, 38 and 15 at the Savannah River Site as a part of the 'In-Service Inspection (ISI) Program for High Level Waste Tanks.' 1 The inspections were performed from the annular space of the waste storage tanks. The inspections included thickness mapping and crack detection scans on specified areas of the tanks covering all present and historic interface levels and selected welds with particular emphasis on the vapor space regions. Including the tanks in this report, all of the 27 Type III tanks at SRS have been inspected in accordance with the ISI plan. Of the four Type III tanks examined this year, all had areas of reportable thickness in either the Primary or Secondary tank. All of these areas on the primary tank are attributed to fabrication artifacts. None of the four Type III tanks examined this year showed evidence of service induced thinning on the primary wall. All four tanks had secondary wall and/or floor plates where the remaining thickness measured below the 10% wall loss criteria. Tank 15, a Type II, non-stress relieved, waste tank was also inspected this fiscal year as part of the ISI program. The same examination techniques were used on Tank 15 as on the Type III tanks. Tank 15 has been out of service due to leakage from stress corrosion cracking (SCC). Inspections were performed to validate known corrosion models and determine if crack growth occurred since the previous examination five years ago. Several cracks were found to have increased in length perpendicular to the weld seam. In the areas of the 27 Type III tanks inspected to date, ten tanks have reportable thickness in the primary wall and 17 have reportable thickness in the secondary tank walls or floor. All of the reportable thickness areas in the primary walls are from fabrication artifacts. Incipient pitting has been detected in five of the 27 Type III primary tanks. No cracking was

  2. Water-waves on linear shear currents. A comparison of experimental and numerical results.

    Science.gov (United States)

    Simon, Bruno; Seez, William; Touboul, Julien; Rey, Vincent; Abid, Malek; Kharif, Christian

    2016-04-01

    Propagation of water waves can be described for uniformly sheared current conditions. Indeed, some mathematical simplifications remain applicable in the study of waves whether there is no current or a linearly sheared current. However, the widespread use of mathematical wave theories including shear has rarely been backed by experimental studies of such flows. New experimental and numerical methods were both recently developed to study wave current interactions for constant vorticity. On one hand, the numerical code can simulate, in two dimensions, arbitrary non-linear waves. On the other hand, the experimental methods can be used to generate waves with various shear conditions. Taking advantage of the simplicity of the experimental protocol and versatility of the numerical code, comparisons between experimental and numerical data are discussed and compared with linear theory for validation of the methods. ACKNOWLEDGEMENTS The DGA (Direction Générale de l'Armement, France) is acknowledged for its financial support through the ANR grant N° ANR-13-ASTR-0007.

  3. High-performance control of a three-phase voltage-source converter including feedforward compensation of the estimated load current

    Energy Technology Data Exchange (ETDEWEB)

    Leon, Andres E.; Solsona, Jorge A.; Busada, Claudio; Chiacchiarini, Hector [Instituto de Investigaciones en Ingenieria Electrica (IIIE) UNS-CONICET, Universidad Nacional del Sur, Av. Alem 1253, Bahia Blanca 8000 (Argentina); Valla, Maria Ines [Laboratorio de Electronica Industrial, Control e Instrumentacion (LEICI) and CONICET, Facultad de Ingenieria, Universidad Nacional de La Plata, La Plata 1900 (Argentina)

    2009-08-15

    In this paper a new control strategy for voltage-source converters (VSC) is introduced. The proposed strategy consists of a nonlinear feedback controller based on feedback linearization plus a feedforward compensation of the estimated load current. In our proposal an energy function and the direct-axis current are considered as outputs, in order to avoid the internal dynamics. In this way, a full linearization is obtained via nonlinear transformation and feedback. An estimate of the load current is feedforwarded to improve the performance of the whole system and to diminish the capacitor size. This estimation allows to obtain a more rugged and cheaper implementation. The estimate is calculated by using a nonlinear reduced-order observer. The proposal is validated through different tests. These tests include performance in presence of switching frequency, measurement filters delays, parameters uncertainties and disturbances in the input voltage. (author)

  4. Determinants of exercise-induced oxygen desaturation including pulmonary emphysema in COPD: Results from the ECLIPSE study.

    Science.gov (United States)

    Andrianopoulos, Vasileios; Celli, Bartolome R; Franssen, Frits M E; Pinto-Plata, Victor M; Calverley, Peter M A; Vanfleteren, Lowie E G W; Vogiatzis, Ioannis; Vestbo, Jørgen; Agusti, Alvar; Bakke, Per S; Rennard, Stephen I; MacNee, William; Tal-Singer, Ruth; Yates, Julie C; Wouters, Emiel F M; Spruit, Martijn A

    2016-10-01

    Exercise-induced oxygen desaturation (EID) is related to mortality in patients with chronic obstructive pulmonary disease (COPD). We investigated: (1) the prevalence of EID; (2) the relative-weight of several physiological determinants of EID including pulmonary emphysema, and (3) the relationship of EID with certain patients' clinical characteristics. Data from 2050 COPD patients (age: 63.3 ± 7.1years; FEV1: 48.7 ± 15.7%pred.) were analyzed. The occurrence of EID (SpO2post ≤88%) at the six-minute walking test (6MWT) was investigated in association with emphysema quantified by computed-tomography (QCT), and several clinical characteristics. 435 patients (21%) exhibited EID. Subjects with EID had more QCT-emphysema, lower exercise capacity and worse health-status (BODE, ADO indexes) compared to non-EID. Determinant of EID were obesity (BMI≥30 kg/m(2)), impaired FEV1 (≤44%pred.), moderate or worse emphysema, and low SpO2 at rest (≤93%). Linear regression indicated that each 1-point increase on the ADO-score independently elevates odds ratio (≤1.5fold) for EID. About one in five COPD patients in the ECLIPSE cohort present EID. Advanced emphysema is associated with EID. In addition, obesity, severe airflow limitation, and low resting oxygen saturation increase the risk for EID. Patients with EID in GOLD stage II have higher odds to have moderate or worse emphysema compared those with EID in GOLD stage III-IV. Emphysematous patients with high ADO-score should be monitored for EID.

  5. Tennessee Valley region study: potential year 2000 radiological dose to population resulting from nuclear facility operations. [Includes glossary

    Energy Technology Data Exchange (ETDEWEB)

    None

    1978-06-01

    A companion report, DOE/ET-0064/1, presents a geographic, cultural, and demographic profile of the Tennessee Valley Region study area. This report describes the calculations of radionuclide release and transport and of the resultant dose to the regional population, assuming a projected installed capacity of 220,000 MW in the year 2000, of which 144,000 MW would be nuclear. All elements of the fuel cycle were assumed to be in operation. The radiological dose was calculated as a one-year dose based on ingestion of 35 different food types as well as for nine non-food pathways, and was reported as dose to the total body and for six specific organs for each of four age groups (infant, child, teen, and adult). Results indicate that the average individual would receive an incremental dose of 7 x 10/sup -4/ millirems in the year 2000 from the operation of nuclear facilities within and adjacent to the region, five orders of magnitude smaller than the dose from naturally occurring radiation in the area. The major contributor to dose was found to be tritium, and the most significant pathways were immersion in air, inhalation of air, transpiration of tritium (absorption through the skin), and exposure radionuclide-containing soil. 60 references.

  6. Results of extralevator abdominoperineal resection for low rectal cancer including quality of life and long-term wound complications.

    Science.gov (United States)

    Welsch, Thilo; Mategakis, Vyron; Contin, Pietro; Kulu, Yakup; Büchler, Markus W; Ulrich, Alexis

    2013-04-01

    Extralevator abdominoperineal resection (APR) for low rectal cancer has been adopted by centers to improve oncological outcome. The present study aimed to investigate oncological results, wound complications, and quality of life (QoL). Patients who underwent extralevator APR for rectal cancer between 2007 and 2011 were identified retrospectively. QoL status was assessed using the European Organisation for Research and Treatment of Cancer (EORTC) QLQ-CR30 and CR29 questionnaires. Thirty laparoscopic (n = 7) or open (n = 23) extralevator APRs were performed in 17 male and 13 female patients. The mortality was zero; circumferential margin involvement occurred in two cases (6.7 %); and there was no bowel perforation. No local recurrence was noted after a median follow-up of 28.3 months; however, six patients died, and eight developed distant metastases. Perineal wound complications were found in 46.6 % of patients, and all were managed conservatively. Fifty percent of the patients reported persistent perineal pain at the follow-up exam. QoL was assessed 7 to 46 months after surgery, and the global health status (70.6) was comparable to the EORTC reference group and published conventional APR series. The QLQ-CR29 module revealed high mean symptom scores for urinary frequency (48.1), incontinence (30.5), and impotence (79.1). Extralevator APR can control local recurrence but not distant metastases of low rectal cancer. The extended perineal resection appears not to decrease general QoL, but it results in a high rate of perineal wound complications. Genitourinary functions are often impaired, even in the long term, and further improvements to the technique must seek to reduce genitourinary harm.

  7. Detailed magnetic model simulations of the H- injection chicane magnets for the CERN PS Booster Upgrade, including eddy currents and influence on beam dynamics

    CERN Document Server

    Benedetto, E; Borburgh, J; Carli, C; Martini, M; Forte, V

    2014-01-01

    The CERN PS Booster will be upgraded with an H- injection system. The chicanemagnets for the injection bump ramp-down in 5 ms and generate eddy currents in the inconel vacuum chamber which perturb the homogeneity of the magnetic field. The multipolar field components are extracted from 3D OPERA simulations and are included in the lattice model. The -beating correction is computed all along the ramp and complete tracking simulations including space-charge are performed to evaluate the impact of these perturbations and correction on beam dynamics.

  8. A Failure Mode in Dense Infrared Detector Arrays Resulting in Increased Dark Current

    Science.gov (United States)

    Pinkie, Benjamin; Bellotti, Enrico

    2016-09-01

    In this paper, we investigate a failure mode that arises in dense infrared focal plane detector arrays as a consequence of the interactions of neighboring pixels through the minority carrier profiles in the common absorber layer. We consider the situation in which one pixel in a hexagonal array becomes de-biased relative to its neighbors and show that the dark current in the six neighboring pixels increases exponentially as a function of the difference between the nominal and anomalous biases. Moreover, we show that the current increase in the six nearest-neighbor pixels is in total larger than that by which the current in the affected pixel decreases, causing a net increase in the dark current. The physical origins of this effect are explained as being due to increased lateral diffusion currents that arise as a consequence of breaking the symmetry of the minority carrier profiles. We then perform a parametric study to quantify the magnitude of this effect for a number of detector geometric parameters, operating temperatures, and spectral bands. Particularly, numerical simulations are carried out for short-, mid-, and long-wavelength HgCdTe infrared detectors operating between 77 K and 210 K. We show that this effect is most prevalent in architectures for which the lateral diffusion current is the largest component of the total dark current—high operating temperature devices with narrow epitaxial absorber thicknesses and pitches small compared to the diffusion length of minority carriers. These results could prove significant particularly for short- and mid-wave infrared detectors, which are typically designed to fit these conditions.

  9. Experimental results of current distribution in Rutherford-type LHC cables

    CERN Document Server

    Verweij, A P

    2000-01-01

    Current distribution among the wires of multi-strand superconducting cables is an important item for accelerator magnets. A non-uniform distribution could cause additional field distortions in the magnet bore and can as well be one of the reasons of premature quenching. Since two years electrical measurements on superconducting Rutherford-type cables are performed at CERN as part of the reception tests for the Large Hadron Collider (LHC). Cable samples of 2.4 m length are tested at currents up to 32 kA, temperatures around 1.9 and 4.3 K, and fields up to 10 T, applied perpendicularly as well as parallel to the broad face of the cable. Last year, an array of 24 Hall probes was installed in the test set-up in order to measure the self-field of the cable samples along one cable pitch. Each of the probes measures the local field generated by the current in the strands close by, and the results of the all probes reflect therefore the distribution of the strand currents. Experiments are done varying the applied fie...

  10. Results of many-year subsatellite measurements of current fine structure in northeastern Black Sea

    Science.gov (United States)

    Lavrova, Olga; Krayushkin, Evgeny; Kalashnikova, Nina

    Results of subsatellite measurements of coastal currents in the shelf zone of northeastern Black Sea are presented. The measurements have been performed every year since 2006 in June and September-October months near the Gelendzhik Bay. The main instruments used are Acoustic Doppler Current Profilers (ADCP) and CTD probes. Ground and ship measurements were conducted simultaneously with satellite imaging in microwave (ASAR Envisat, ERS-2, RADARSAT-2, TerraSAR-X), visible and infrared (OLI Landsat-8, ETM+ Landsat-7, TM Landsat-5, MODIS Terra/Aqua, AVHRR NOAA) ranges. The investigations performed revealed spatial, depth and temporal variability of current direction and velocity in the shelf zone. Multiple instances of counter-currents opposing to the Ring Current were registered. In our view, they are associated with a passage of small-scale anticyclonic eddies across the region of interest. The 3D structure of the eddies in the upper quasi-uniform layer was analyzed based on ADCP data. The use of high resolution (3 m) SAR data in combination with ADCP measurements at the resolution of 0.5 m allowed us to detect a number of internal wave trains. Form ADCP and thermistors records, their amplitudes were estimated to reach 5-8 m. Joint analysis of satellite SAR and subsatellite data gave an assessment of their typical wavelength at 90-100 m. Generation mechanisms of these internal waves are suggested. Another phenomenon of interest observed in the region of the measurements is surface manifestations of ring waves near localized natural and anthropogenic generation sources. Such ring waves are most frequently found in the anchor area for ships, whose oscillations can be the source of their generation. The work was in part supported by the Russian Foundation for Basic Research (projects #14-05-00520-а, and 13-07-12017-ofi_m). SAR data from RADARSAT-2 and TerraSAR-X were obtained under SOAR RADARSAT-2/TerraSAR-X Project #5074.

  11. Current situation of depression healthcare in Spain: results of a psychiatrists' survey

    Directory of Open Access Journals (Sweden)

    Belén Martín-Águeda

    2006-12-01

    Full Text Available Objective: To analyze the current situation of healthcare for depression in Spain, according to psychiatrists opinion, and how it has evolved over the last 20 years, comparativily with the results reported in previous studies of our group. Methods: Throughout 2002, we recorded the opinions of 101 specialists in psychiatry after asking them to fill out structured questionnaires in which they rated care, clinical, therapeutic and care quality. Results: The presence of depressive disorders in healthcare is substantial, despite the high figures for "concealed epidemiology", with an increase in these last 20 years of disorders comorbid with anxiety. Currently, most patients arrive at the psychiatrist having been referred by their general practitioners (GP, as there is now less reluctance in depressive patients to such referral. In the last years there has been an increase in pharmacological treatment, with adverse effects of the drugs representing the major obstacle to non-adherence to such treatment. Selective serotonin reuptake inhibitors (SSRIs constitute the pharmacological group of choice, and are the drugs most commonly used in the treatment of depression, together with venlafaxine. Areas where there is a need for improvement are time devoted to consultation, coordination between GPs and psychiatrists, waiting lists, and resources available to Mental Health Units. Conclusions: Current situation of depression healthcare in Spain has substantially changed in recent years, improving in some aspects, thanks, in part, to the attitudes of GPs with this disorder and to evolution of pharmacological treatment.

  12. Treatment of gastric outlet obstruction that results fromunresectable gastric cancer: Current evidence

    Institute of Scientific and Technical Information of China (English)

    2016-01-01

    Malignant gastric outlet obstruction (GOO) is a commoncondition that results from locally advanced malignanciesin the upper gastrointestinal tract, such aspancreatic, gastric, and other carcinomas. Two typesof procedures for malignant GOO, namely, gastrojejunostomy(GJ) with laparotomy or a laparoscopicapproach and endoscopic stenting (ES), are currentlyavailable. Although numerous previous reports haveclarified the benefits and drawbacks of each procedure,whether GJ or ES should be used in patients with GOOthat results from gastric cancer who may have a longerlife expectancy than patients with other malignancieshas not been determined. In this review, which focuseson gastric cancer-induced GOO, we analyzed the twosystematic reviews and a meta-analysis that comparedGJ and ES and outlined the current status of GOOtreatment. We also provide an updated review thatincludes laparoscopic GJ. Various data from 13 studiesin one review and 6 studies in another review wereanalyzed. Although the main results of the presentreview indicated that both GJ and ES were efficacioustreatments in patients with GOO that resulted fromgastric cancer, current evidence suggests that GJ maybe the preferable procedure given its good performancestatus and improved prognosis in gastric cancer patients.

  13. Iterative reconstruction for quantitative computed tomography analysis of emphysema: consistent results using different tube currents

    Directory of Open Access Journals (Sweden)

    Yamashiro T

    2015-02-01

    Full Text Available Tsuneo Yamashiro,1 Tetsuhiro Miyara,1 Osamu Honda,2 Noriyuki Tomiyama,2 Yoshiharu Ohno,3 Satoshi Noma,4 Sadayuki Murayama1 On behalf of the ACTIve Study Group 1Department of Radiology, Graduate School of Medical Science, University of the Ryukyus, Nishihara, Okinawa, Japan; 2Department of Radiology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan; 3Department of Radiology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan; 4Department of Radiology, Tenri Hospital, Tenri, Nara, Japan Purpose: To assess the advantages of iterative reconstruction for quantitative computed tomography (CT analysis of pulmonary emphysema. Materials and methods: Twenty-two patients with pulmonary emphysema underwent chest CT imaging using identical scanners with three different tube currents: 240, 120, and 60 mA. Scan data were converted to CT images using Adaptive Iterative Dose Reduction using Three Dimensional Processing (AIDR3D and a conventional filtered-back projection mode. Thus, six scans with and without AIDR3D were generated per patient. All other scanning and reconstruction settings were fixed. The percent low attenuation area (LAA%; < -950 Hounsfield units and the lung density 15th percentile were automatically measured using a commercial workstation. Comparisons of LAA% and 15th percentile results between scans with and without using AIDR3D were made by Wilcoxon signed-rank tests. Associations between body weight and measurement errors among these scans were evaluated by Spearman rank correlation analysis. Results: Overall, scan series without AIDR3D had higher LAA% and lower 15th percentile values than those with AIDR3D at each tube current (P<0.0001. For scan series without AIDR3D, lower tube currents resulted in higher LAA% values and lower 15th percentiles. The extent of emphysema was significantly different between each pair among scans when not using AIDR3D (LAA%, P<0.0001; 15th percentile, P<0.01, but was not

  14. Test Results For a 25-m Prototype Fault Current Limiting HTS Cable for Project Hydra

    Energy Technology Data Exchange (ETDEWEB)

    Rey, Christopher M [ORNL; Duckworth, Robert C [ORNL; Demko, Jonathan A [ORNL; Ellis, Alvin R [ORNL; Gouge, Michael J [ORNL; James, David Randy [ORNL; Tuncer, Enis [ORNL

    2010-01-01

    The Oak Ridge National Laboratory (ORNL) has tested a 25-m long prototype High Temperature Superconducting (HTS) cable with inherent Fault-Current Limiting (FCL) capability at its recently upgraded HTS cable test facility in Oak Ridge, TN. The HTS-FCL cable and terminations were designed and fabricated by Ultera, which is a joint venture of Southwire and nkt cables with FCL features and HTS wire provided by American Superconductor Corporation. The overall project is sponsored by the U.S. Department of Homeland Security. The ultimate goal of the 25-m HTS-FCL cable test program was to verify the design and ensure the operational integrity for the eventual installation of a ~ 200-m fully functional HTS-FCL cable in the Consolidated Edison electric grid located in downtown New York City. The 25-m HTS-FCL cable consisted of a three-phase (3- ) Triax design with a cold dielectric between the phases. The HTS-FCL cable had an operational voltage of 13.8 kV phase-to-phase and an operating current of 4000 Arms per phase, which is the highest operating current to date of any HTS cable. The 25-m HTS-FCL cable was subjected to a series of cryogenic and electrical tests. Test results from the 25-m HTS-FCL cable are presented and discussed.

  15. Current regional stress field and the resultant crustal deformation in SE Korea and their tectonic implication

    Science.gov (United States)

    Kim, M. C.; Cho, H.; Son, M.

    2014-12-01

    To determine current regional stress field and to characterize the resultant crustal deformation in SE Korea, Quaternary fault, focal mechanism, and geotechnical in-situ stress data were synthetically analyzed. The Quaternary faults are extensively observed along major inherited fault zones and show compatible orientations with general trends of the inherited faults. Most of the Quaternary faults have a top-to-the-west thrust geometry and kinematics and show a tendency of upward-decreasing dip angle and upward-narrowing gouge zone. Slip-sense indicators and paleo-stress field reconstructions indicate that the faults resulted from reverse or transpressional faulting under an E-W compression. All the magnetic fabrics (AMS) of the fault gouges also indicate the prevailing reverse-slip faulting under an ENE-WNW compression. The dominant oblate magnetic fabrics parallel to fault plane and the degrees of anisotropy increasing in proportion to their oblatenesses indicate that the fabrics have formed by a progressive deformation due to continuous simple shear during the last reactivation stage as reverse faulting. The focal mechanism study in and around the Korean Peninsula show the horizontally clustered P-axes in ENE-WSW direction and the girdle-distributed T-axes in NNW trend. The geotechnical in-situ stress data in south Korea also show NE- or ENE-trending maximum horizontal stress. The current crustal deformation in Korea thus can be characterized by contractional structures produced under a regional E-W or ENE-WSW compression stress field, and most of the Quaternary faults resulted from the local re-activation of appropriately oriented inherited major faults. Considering the tectonic setting and structural features in Asia during the Neogene, the current stress regime is interpreted to have been caused by the cooperation of westward shallow subduction of Pacific Plate and collision of Indian and Eurasian continents since about 5-3.5 Ma.

  16. Current status of a hepatitis C vaccine: encouraging results but significant challenges ahead

    DEFF Research Database (Denmark)

    Mikkelsen, Marianne; Bukh, Jens

    2007-01-01

    Persistent hepatitis C virus (HCV) infection affects 170 million people worldwide. Acute HCV infection is often asymptomatic, but many infected individuals develop persistent infections that may lead to development of end-stage liver diseases, including liver cirrhosis and hepatocellular carcinoma....... Thus, an HCV vaccine that could significantly lower the chronicity rate would have a major impact on the disease burden. Unfortunately, HCV is a highly mutable virus, and escape mutations can undermine vaccine-induced virus-specific immunity. Also, HCV exists as multiple genotypes, and so genotype......-specific vaccines might be required to achieve broad protection. Finally, vaccine development has been hampered by the lack of a small animal model and cell culture systems, but these are currently being established. Despite these obstacles, several vaccine candidates tested in the chimpanzee HCV model have shown...

  17. Current status of a hepatitis C vaccine: encouraging results but significant challenges ahead

    DEFF Research Database (Denmark)

    Mikkelsen, Marianne; Bukh, Jens

    2007-01-01

    -specific vaccines might be required to achieve broad protection. Finally, vaccine development has been hampered by the lack of a small animal model and cell culture systems, but these are currently being established. Despite these obstacles, several vaccine candidates tested in the chimpanzee HCV model have shown......Persistent hepatitis C virus (HCV) infection affects 170 million people worldwide. Acute HCV infection is often asymptomatic, but many infected individuals develop persistent infections that may lead to development of end-stage liver diseases, including liver cirrhosis and hepatocellular carcinoma....... Thus, an HCV vaccine that could significantly lower the chronicity rate would have a major impact on the disease burden. Unfortunately, HCV is a highly mutable virus, and escape mutations can undermine vaccine-induced virus-specific immunity. Also, HCV exists as multiple genotypes, and so genotype...

  18. Bad results obtained from the current public health policies and recommendations of hydration

    Directory of Open Access Journals (Sweden)

    Ismael San Mauro Martín

    Full Text Available Introduction: Achieving an adequate intake of water is crucial within a balanced diet. For that purpose, dietary guidelines for healthy eating and drinking are an important consideration and need to be updated and disseminated to the population. Aim: We aimed to evaluate the liquid intake habits of a Mediterranean and Latin American population (Spain-Portugal and Mexico-Uruguay and if they support the current recommendations of hydration by the EFSA. Methods: A record of fluid intake was obtained from 1,168 participants from 4 countries above; and then compared with current consensus about hydration 1,600 mL/day (female and 2,000 mL/day (male. Results: The average fluid intake slightly surpassed the recommended: mean of 2,049 mL/day (2,223 mL in males, 1,938 mL in females. Portugal stood out due to its lower intake (mean of 1,365 mL/day. Water contributed the largest part to total fluid intake (37% in all countries (mean of 1,365 mL/day. Hot beverages (18% and milk and derivates (17% follow water in highest consumption. The 20% of males and only 0.3% of females knew recommendations of hydration, while 63.3% of males and 62% of females followed them. Only 8.4% of people who follow the recommendations know them. Conclusion: The people studied surpassed the recommendation, although the majority did not realize. Future research should examine actual beverage consumption patterns and evaluate if the current consensuses are correctly adapted to the population needs. Hydration's policies should be transmitted to the population for their knowledge and adequate compliance.

  19. Technological insights: Combined impedance manometry for esophageal motility testing-current results and further implications

    Institute of Scientific and Technical Information of China (English)

    Huan Nam Nguyen; Gerson Ricardo Souza Domingues; Frank Lammert

    2006-01-01

    This review focuses on current aspects of the novel technology of combined impedance manometry for esophageal motility testing. It presents methodological features, summarizes current results and discusses implications for further research. The combined technique assesses simultaneously bolus transport and associated peristalsis, thus allowing detailed analysis of the relationships between bolus transit and esophageal motility. Recent studies demonstrate that combined impedance manometry provides important additional information about esophageal motility as compared to conventional manometry: (1) monitoring of bolus transport patterns, (2) calculation of bolus transit parameters, (3) evaluation of bolus clearance,(4) monitoring of swallow associated events such as air movement and reflux, and (5) investigation of the relationships between bolus transit and LES relaxation.Studies with healthy subjects have identified several useful parameters for comprehensive assessment of eosphageal function. These parameters were found to be pathological in patients with classical achalasia,mild GERD, and ineffective esophageal motility. The technology of combined impedance manometry provides an important new tool for esophageal function testing,advancing both clinical and basic research. However,several important issues remain to be standardized to make the technique suitable for widely clinical use.

  20. Current IGEX Results for Neutrinoless Double-Beta Decay of {sup 76}Ge

    Energy Technology Data Exchange (ETDEWEB)

    Gonzalez, D.; Aalseth, C.E.; Avignone, F.T.; Brodzinski, R.L.; Cebrian, S.; Garcia, E.; Hensley, W.K.; Irastorza, I.G.; Kirpichnikov, I.V.; Klimenko, A.A.; Miley, H.S.; Morales, A.; Morales, J.; Ortiz de Solorzano, A.; Osetrov, S.B.; Pogosov, V.S.; Puimedon, J.; Reeves, J.H.; Sarsa, M.L.; Scopel, S.; Smolnikov, A.A.; Tamanyan, A.G.; Vasenko, A.A.; Vasiliev, S.I.; Villar, J.A

    2000-06-01

    The International Germanium Experiment (IGEX) is currently operating three 2-kg enriched germanium detectors in the Canfranc Underground Laboratory (Spain) at 2450 mwe, in a search for the neutrinoless double-beta decay of {sup 76}Ge. The detectors are equipped with Pulse Shape Analysis electronics. This implementation of Pulse Shape Discrimination results in a rejection of 60%-80% of the background in the 2.0-2.5 MeV energy interval. Analysis of 116.75 mole-years of data yields a lower bound {>=} 1.57 x 10{sup 25}y (or T{sup 0{nu}}{sub 1/2} {>=} 1.13 x 10{sup 25}y without PSD) (90% C.L.) corresponding to (m{sub {nu}}) < (0.33 - 1.31) eV, depending on the theoretical nuclear matrix elements used to extract the neutrino mass parameter.

  1. Current IGEX Results for Neutrinoless Double-Beta Decay of 76Ge

    Science.gov (United States)

    González, D.; Aalseth, C. E.; Avignone, F. T., Jr.; Brodzinski, R. L.; Cebrián, S.; García, E.; Hensley, W. K.; Irastorza, I. G.; Kirpichnikov, I. V.; Klimenko, A. A.; Miley, H. S.; Morales, A.; Morales, J.; Ortiz de Solórzano, A.; Osetrov, S. B.; Pogosov, V. S.; Puimedón, J.; Reeves, J. H.; Sarsa, M. L.; Scopel, S.; Smolnikov, A. A.; Tamanyan, A. G.; Vasenko, A. A.; Vasiliev, S. I.; Villar, J. A.

    2000-06-01

    The International Germanium Experiment (IGEX) is currently operating three 2-kg enriched germanium detectors in the Canfranc Underground Laboratory (Spain) at 2450 mwe, in a search for the neutrinoless double- beta decay of 76Ge. The detectors are equipped with Pulse Shape Analysis electronics. This implementation of Pulse Shape Discrimination results in a rejection of 60%-80% of the background in the 2.0-2.5 MeV energy interval. Analysis of 116.75 mole-years of data yields a lower bound ≥ 1.57 × 10 25y ( or T {1}/{2}0ν ≥ 1.13 × 10 25y without PSD) (90% C.L.) corresponding to < (0.33 - 1.31) eV, depending on the theoretical nuclear matrix elements used to extract the neutrino mass parameter.

  2. If ionospheric and geomagnetic disturbances observed before strong earthquakes may result from simultaneous impact of space weather on all geospheres including solid earth

    Science.gov (United States)

    Khachikyan, Galina

    2016-07-01

    It is revealed in previous decades that ionospheric disturbances precede strong earthquakes, thus, the ionospheric precursors of strong earthquakes are now under developing [Pulinets and Boyarchuk, 2004]. Simultaneously, it is revealed that strong earthquakes may be preceded by geomagnetic disturbances as well, as a result, the geomagnetic variations, for example, in the ULF band, are considered now as precursory signals [Fraser-Smith, 1990, doi/10.1029/GL017i009p01465]. At the same time, there is currently no reliable theory nor for ionospheric or to magnetic precursors of earthquakes. Moreover, several researches have reexamined some of above results and concluded that observed magnetic disturbances before strong earthquakes could be generated by other sources, such as global magnetic activity [e.g. Campbell, 2009, doi/10.1029/2008JA013932], and that ionospheric anomalies can also be an effect of the increase of the global magnetic activity [e. g. Masci and Thomas, 2015, doi:10.1002/2015RS005734]. Taking into account such conclusions, one may suggest that the observed ionospheric and geomagnetic disturbances before strong earthquakes might be due to simultaneous influence of a space weather on the complicated surrounding system including the solid earth. This report presents some statistical results to prove such suggestion. In particular, it is shown [Khachikyan et al., 2012, doi:10.4236/ijg.2012.35109] that maximal possible earthquake magnitude (seismic potential) can be determined, in first approximation, on the base of geomagnetic Z-component measured in the Geocentric Solar Magnetosphere (GSM) coordinate system, in which the space weather impact on the earth's environment, due to reconnection of the solar wind magnetic field with the earth's magnetic field, is more ordered.

  3. Parathyroid scintigraphy protocols in Finland in 2010. Results of the query and current status

    Energy Technology Data Exchange (ETDEWEB)

    Tunninen, V. [The Dept. of Nuclear Medicine, Satakunta Central Hospital, Pori (Finland); Kauppinen, T. [HUS Helsinki Medical Imaging Centre, Helsinki Univ. Hospital (Finland); Eskola, H. [The Dept. of Biomedical Engineering, Tampere Univ. of Technology (Finland); Koskinen, M.O. [Medical Imaging Centre, Tampere Univ. Hospital (Finland)

    2010-07-01

    The goal of this study was to describe current clinical parathyroid scintigraphy (PS) protocols in Finland. Methods: All departments of nuclear medicine in Finland were contacted, and instructions regarding PS were requested. Results: Instructions regarding PS were received from all of the departments that perform PS (n = 19). Seven hundred and sixty-nine PS studies were performed in 2009 (between 7 and 209 per hospital). Three methods of PS were used. The dual-phase method with {sup 99m}Tc-sestamibi is used in seven hospitals, the dual-tracer method with {sup 123}I/{sup 99m}Tc-sestamibi in eleven, and {sup 99m}TcO{sub 4}/{sup 99m}Tc-sestamibi in one hospital. The activities of {sup 99m}Tc-sestamibi, {sup 123}I and {sup 99m}TcO{sub 4} were 150-800 MBq, 10-30 MBq and 50 MBq, respectively. The anterior image with parallel-hole collimators, the anterior image with pinhole collimator, the oblique angles with pinhole collimator, SPECT and hybrid CT with SPECT were acquired in 84%, 26%, 16%, 63%, and 42% of the hospitals, respectively. Because the imaging techniques were combined, one to four acquisitions were performed per patient. Scatter and attenuation correction were used in five protocols. A correction for crosstalk of {sup 123}I and {sup 99m}Tc gamma energies was not used, but the amount of crosstalk was decreased by using narrow or asymmetric energy windows in all dual isotope protocols. Conclusion: 19 hospitals used 18 different study protocols. Thus, significant variability exists in the current practice of PS in Finland. The protocols should be tested with known phantoms to determine any differences in sensitivities for detecting small active structures. Further studies with phantoms are needed to determine the optimal imaging techniques. The results of these phantom studies will provide guidelines for proposing national recommendations for PS. (orig.)

  4. Presal36: a high resolution ocean current model for Brazilian pre-salt area: implementation and validation results

    Energy Technology Data Exchange (ETDEWEB)

    Schoellkopf, Jacques P. [Advanced Subsea do Brasil Ltda., Rio de Janeiro, RJ (Brazil)

    2012-07-01

    The PRESAL 36 JIP is a project for the development of a powerful Ocean Current Model of 1/36 of a degree resolution, nested in an existing Global Ocean global Model, Mercator PSY4 (1/12-a-degree resolution ), with tide corrections, improved bathymetry accuracy and high frequency atmospheric forcing (every 3 hours). The simulation outputs will be the 3 dimensional structure of the velocity fields (u,v,w) at 50 vertical levels over the water column, including geostrophic, Ekman and tidal currents, together with Temperature, Salinity and sea surface height at a sub-mesoscale spatial resolution. Simulations will run in hindcast, nowcast and forecast modes, with a temporal resolution of 3 hours . This Ocean current model will allow to perform detailed statistical studies on various areas using conditions analysed using hindcast mode, short term operational condition prediction for various surface and sub sea operations using realtime and Forecast modes. The paper presents a publication of significant results of the project, in term of pre-sal zoomed model implementation, and high resolution model validation. It demonstrate the capability to properly describe ocean current phenomenon at beyond mesoscale frontier. This project demonstrate the feasibility of obtaining accurate information for engineering studies and operational conditions, based on a 'zoom technique' starting from global ocean models. (author)

  5. Modelling of transitions between L- and H-mode in JET high plasma current plasmas and application to ITER scenarios including tungsten behaviour

    Science.gov (United States)

    Koechl, F.; Loarte, A.; Parail, V.; Belo, P.; Brix, M.; Corrigan, G.; Harting, D.; Koskela, T.; Kukushkin, A. S.; Polevoi, A. R.; Romanelli, M.; Saibene, G.; Sartori, R.; Eich, T.; Contributors, JET

    2017-08-01

    The dynamics for the transition from L-mode to a stationary high Q DT H-mode regime in ITER is expected to be qualitatively different to present experiments. Differences may be caused by a low fuelling efficiency of recycling neutrals, that influence the post transition plasma density evolution on the one hand. On the other hand, the effect of the plasma density evolution itself both on the alpha heating power and the edge power flow required to sustain the H-mode confinement itself needs to be considered. This paper presents results of modelling studies of the transition to stationary high Q DT H-mode regime in ITER with the JINTRAC suite of codes, which include optimisation of the plasma density evolution to ensure a robust achievement of high Q DT regimes in ITER on the one hand and the avoidance of tungsten accumulation in this transient phase on the other hand. As a first step, the JINTRAC integrated models have been validated in fully predictive simulations (excluding core momentum transport which is prescribed) against core, pedestal and divertor plasma measurements in JET C-wall experiments for the transition from L-mode to stationary H-mode in partially ITER relevant conditions (highest achievable current and power, H 98,y ~ 1.0, low collisionality, comparable evolution in P net/P L-H, but different ρ *, T i/T e, Mach number and plasma composition compared to ITER expectations). The selection of transport models (core: NCLASS  +  Bohm/gyroBohm in L-mode/GLF23 in H-mode) was determined by a trade-off between model complexity and efficiency. Good agreement between code predictions and measured plasma parameters is obtained if anomalous heat and particle transport in the edge transport barrier are assumed to be reduced at different rates with increasing edge power flow normalised to the H-mode threshold; in particular the increase in edge plasma density is dominated by this edge transport reduction as the calculated neutral influx across the

  6. Hip resurfacing arthroplasty: mid-term results in 486 cases and current indication in our institution.

    Science.gov (United States)

    Ribas, Manuel; Cardenas, Carlomagno; Astarita, Emanuele; Moya, Esther; Bellotti, Vittorio

    2014-10-02

    In the previous decade, metal-on-metal hip resurfacing has been considered an attractive option and theoretically advantageous over conventional total hip arthroplasty, especially in young active patients. Different authors have reported favourable mid-term clinical and functional results with acceptable survival rates. Proper indication and planning, as accurate technical execution have been advocated to be crucial elements for success.Concerns regarding serum metal ion levels and possible clinical implications have led in the last years to a decline in the use of metal-on-metal hip resurfacing and metal-on-metal bearings in general.The aim of this study is to present the results of our first 486 cases of hybrid hip resurfacing arthroplasties with a second generation cementing technique, and to describe our current restricted indication of this type of prosthesis, in the light of recent findings in the literature about the possible complications related to metallosis or improper patient selection. Global survivorship of our series was 97.9% at a mean follow-up of 7.2 years.In the second season of our experience the indication is restrictive. The candidate for a resurfacing hip replacement is a young and active male patient, with good bone quality, that has been made aware of the risks and benefits of this type of prosthesis.

  7. Photospheric Current Spikes and Their Possible Association with Flares - Results from an HMI Data Driven Model

    Science.gov (United States)

    Goodman, Michael; Kwan, Chiman; Ayhan, Bulent; Shang, Eric L.

    2016-01-01

    A data driven, near photospheric magnetohydrodynamic model predicts spikes in the horizontal current density, and associated resistive heating rate per unit volume Q. The spikes appear as increases by orders of magnitude above background values in neutral line regions (NLRs) of active regions (ARs). The largest spikes typically occur a few hours to a few days prior to M or X flares. The spikes correspond to large vertical derivatives of the horizontal magnetic field. The model takes as input the photospheric magnetic field observed by the Helioseismic & Magnetic Imager (HMI) on the Solar Dynamics Observatory (SDO) satellite. This 2.5 D field is used to determine an analytic expression for a 3 D magnetic field, from which the current density, vector potential, and electric field are computed in every AR pixel for 14 ARs. The field is not assumed to be force-free. The spurious 6, 12, and 24 hour Doppler periods due to SDO orbital motion are filtered out of the time series of the HMI magnetic field for each pixel using a band pass filter. The subset of spikes analyzed at the pixel level are found to occur on HMI and granulation scales of 1 arcsec and 12 minutes. Spikes are found in ARs with and without M or X flares, and outside as well as inside NLRs, but the largest spikes are localized in the NLRs of ARs with M or X flares. The energy to drive the heating associated with the largest current spikes comes from bulk flow kinetic energy, not the electromagnetic field, and the current density is highly non-force free. The results suggest that, in combination with the model, HMI is revealing strong, convection driven, non-force free heating events on granulation scales, and that it is plausible these events are correlated with subsequent M or X flares. More and longer time series need to be analyzed to determine if such a correlation exists. Above an AR dependent threshold value of Q, the number of events N(Q) with heating rates greater than or equal to Q obeys a scale

  8. Estimation of the yield of poplars in plantations of fast-growing species within current results

    Directory of Open Access Journals (Sweden)

    Martin Fajman

    2009-01-01

    Full Text Available Current results are presented of allometric yield estimates of the poplar short rotation coppice. According to a literature review it is obvious that yield estimates, based on measurable quantities of a growing stand, depend not only on the selected tree specie or its clone, but also on the site location. The Jap-105 poplar clone (P. nigra x P. maximowiczii allometric relations were analyzed by regression methods aimed at the creation of the yield estimation methodology at a testing site in Domanínek. Altogether, the twelve polynomial dependences of particular measured quantities approved the high empirical data conformity with the tested regression model (correlation index from 0.9033 to 0.9967. Within the forward stepwise regression, factors were selected, which explain best examined estimates of the total biomass DM; i.e. d.b.h. and stem height. Furthermore, the KESTEMONT’s (1971 mo­del was verified with a satisfying conformity as well. Approving presented yield estimation methods, the presented models will be checked in a large-scale field trial.

  9. Current and future delivery of diagnostic electron microscopy in the UK: results of a national survey.

    Science.gov (United States)

    de Haro, Tracey; Furness, Peter

    2012-04-01

    Electron microscopy (EM) remains essential to delivering several specialist areas of diagnosis, especially the interpretation of native renal biopsies. However, there is anecdotal evidence of EM units struggling to survive, for a variety of reasons. The authors sought to obtain objective evidence of the extent and the causes of this problem. An online survey was undertaken of Fellows of the Royal College of Pathologists who use EM in diagnosis. A significant number of EM units anticipate having to close and hence outsource their EM work in the coming years. Yet most existing units are working to full capacity and would be unable to take on the substantial amounts of extra work implied by other units outsourcing their needs. Equipment and staffing are identified by most EM units as the major barriers to growth and are also the main reasons cited for units facing potential closure. In the current financial climate it seems unlikely that units will be willing to make the large investment in equipment and staff needed to take on extra work, unless they can be reasonably confident of an acceptable financial return as a result of increased external referral rates. The case is thus made for a degree of national coordination of the future provision of this specialist service, possibly through the National Commissioning Group or the new National Commissioning Board. Without this, the future of diagnostic EM services in the UK is uncertain. Its failure would pose a threat to good patient care.

  10. STUDENT SATISFACTION, RESULTANT OF MARKETING ORIENTATION OF UNIVERSITY UNDER CURRENT CONDITIONS

    Directory of Open Access Journals (Sweden)

    Florentina DINESCU

    2012-12-01

    Full Text Available The purpose of this work is to present a relevant aspect of marketing approach of the activities carried by universities, respectively knowing, understanding and satisfying students’ needs, the main consumer category of the university product, in the conditions of current market of high education institutions. The universities are put in the position to find solutions to the problems caused by the stakeholders’ characteristics and by the existing competition on the educational market. The approach of marketing orientation in the university implies adapting the educational and scientific research step to create for the institution a brand image as a warranty of its sustainability on a competitive market by considering the needs and expectations of students. The conclusion is that there is a wide specialized literature that shows models that allow an adequate quantification of the students’ satisfaction as a resultant of concerning the insurance of high education quality by using univeristy marketing tools. Starting from the specialized literature, in the work was handled the quantification of the students’ satisfaction that have completed Bachelor and Master cycle in order to improve the activity of the university

  11. HIV-1 Tat protein increases microglial outward K(+ current and resultant neurotoxic activity.

    Directory of Open Access Journals (Sweden)

    Jianuo Liu

    Full Text Available Microglia plays a crucial role in the pathogenesis of HIV-1-associated neurocognitive disorders. Increasing evidence indicates the voltage-gated potassium (Kv channels are involved in the regulation of microglia function, prompting us to hypothesize Kv channels may also be involved in microglia-mediated neurotoxic activity in HIV-1-infected brain. To test this hypothesis, we investigated the involvement of Kv channels in the response of microglia to HIV-1 Tat protein. Treatment of rat microglia with HIV-1 Tat protein (200 ng/ml resulted in pro-inflammatory microglial activation, as indicated by increases in TNF-α, IL-1β, reactive oxygen species, and nitric oxide, which were accompanied by enhanced outward K(+ current and Kv1.3 channel expression. Suppression of microglial Kv1.3 channel activity, either with Kv1.3 channel blockers Margatoxin, 5-(4-Phenoxybutoxypsoralen, or broad-spectrum K(+ channel blocker 4-Aminopyridine, or by knockdown of Kv1.3 expression via transfection of microglia with Kv1.3 siRNA, was found to abrogate the neurotoxic activity of microglia resulting from HIV-1 Tat exposure. Furthermore, HIV-1 Tat-induced neuronal apoptosis was attenuated with the application of supernatant collected from K(+ channel blocker-treated microglia. Lastly, the intracellular signaling pathways associated with Kv1.3 were investigated and enhancement of microglial Kv1.3 was found to correspond with an increase in Erk1/2 mitogen-activated protein kinase activation. These data suggest targeting microglial Kv1.3 channels may be a potential new avenue of therapy for inflammation-mediated neurological disorders.

  12. HAMLET -Human Model MATROSHKA for Radiation Exposure Determination of Astronauts -Current status and results

    Science.gov (United States)

    Reitz, Guenther; Berger, Thomas; Bilski, Pawel; Burmeister, Soenke; Labrenz, Johannes; Hager, Luke; Palfalvi, Jozsef K.; Hajek, Michael; Puchalska, Monika; Sihver, Lembit

    contribute essentially to radiation risk estimations for future interplanetary space exploration by humans, putting them on a solid experimental and theoretical basis. The talk will give an overview of the current status of the MATROSHKA data evaluation and results and comparisons of the first three MTR experimental phases (MTR-1, 2A and 2B). The HAMLET project is funded by the European Commission under the EUs Seventh Frame-work Programme (FP7) under Project Nr: 218817 and coordinated by the German Aerospace Center (DLR) http://www-fp7-hamlet.eu

  13. Is Current CMBR Temperature: The Scale Independent Quantum Gravitational Result of Black Hole Cosmology?

    Science.gov (United States)

    Seshavatharam, U. V. S.; Lakshminarayana, S.

    If one is willing to consider the current cosmic microwave back ground temperature as a quantum gravitational effect of the evolving primordial cosmic black hole (universe that constitutes dynamic space-time and exhibits quantum behavior) automatically general theory of relativity and quantum mechanics can be combined into a `scale independent' true unified model of quantum gravity. By considering the `Planck mass' as the initial mass of the baby Hubble volume, past and current physical and thermal parameters of the cosmic black hole can be understood. Current rate of cosmic black hole expansion is being stopped by the microscopic quantum mechanical lengths. In this new direction authors observed 5 important quantum mechanical methods for understanding the current cosmic deceleration. To understand the ground reality of current cosmic rate of expansion, sensitivity and accuracy of current methods of estimating the magnitudes of current CMBR temperature and current Hubble constant must be improved and alternative methods must be developed. If it is true that galaxy constitutes so many stars, each star constitutes so many hydrogen atoms and light is coming from the excited electron of galactic hydrogen atom, then considering redshift as an index of `whole galaxy' receding may not be reasonable. During cosmic evolution, at any time in the past, in hydrogen atom emitted photon energy was always inversely proportional to the CMBR temperature. Thus past light emitted from older galaxy's excited hydrogen atom will show redshift with reference to the current laboratory data. As cosmic time passes, in future, the absolute rate of cosmic expansion can be understood by observing the rate of increase in the magnitude of photon energy emitted from laboratory hydrogen atom. Aged super novae dimming may be due to the effect of high cosmic back ground temperature. Need of new mathematical methods & techniques, computer simulations, advanced engineering skills seem to be essential

  14. Prediction of SFL Interruption Performance from the Results of Arc Simulation during High-Current Phase

    Science.gov (United States)

    Lee, Jong-Chul; Lee, Won-Ho; Kim, Woun-Jea

    2015-09-01

    The design and development procedures of SF6 gas circuit breakers are still largely based on trial and error through testing although the development costs go higher every year. The computation cannot cover the testing satisfactorily because all the real processes arc not taken into account. But the knowledge of the arc behavior and the prediction of the thermal-flow inside the interrupters by numerical simulations are more useful than those by experiments due to the difficulties to obtain physical quantities experimentally and the reduction of computational costs in recent years. In this paper, in order to get further information into the interruption process of a SF6 self-blast interrupter, which is based on a combination of thermal expansion and the arc rotation principle, gas flow simulations with a CFD-arc modeling are performed during the whole switching process such as high-current period, pre-current zero period, and current-zero period. Through the complete work, the pressure-rise and the ramp of the pressure inside the chamber before current zero as well as the post-arc current after current zero should be a good criterion to predict the short-line fault interruption performance of interrupters.

  15. Opioid Addiction: Social Problems Associated and Implications of Both Current and Possible Future Treatments, including Polymeric Therapeutics for Giving Up the Habit of Opioid Consumption

    Directory of Open Access Journals (Sweden)

    M. Cristina Benéitez

    2017-01-01

    Full Text Available Background. Detoxification programmes seek to implement the most secure and compassionate ways of withdrawing from opiates so that the inevitable withdrawal symptoms and other complications are minimized. Once detoxification has been achieved, the next stage is to enable the patient to overcome his or her drug addiction by ensuring consumption is permanently and completely abandoned, only after which can the subject be regarded as fully recovered. Methods. A systematic search on the common databases of relevant papers published until 2016 inclusive. Results and Conclusion. Our study of the available oral treatments for opioid dependence has revealed that no current treatment can actually claim to be fully effective. These treatments require daily oral administration and, consequently, regular visits to dispensaries, which in most cases results in a lack of patient compliance, which causes fluctuations in drug plasma levels. We then reviewed alternative treatments in the available scientific literature on polymeric sustained release formulations. Research has been done not only on release systems for detoxification but also on release systems for giving up the habit of taking opioids. These efforts have obtained the recent authorization of polymeric systems for use in patients that could help them to reduce their craving for drugs.

  16. Current Arabian Plate Motion From Campaign GPS Measurements in Saudi Arabia: Preliminary Results

    Science.gov (United States)

    Almuslmani, B.; Teferle, F. N.; Bingley, R. M.; Moore, T.

    2007-12-01

    Current investigations of the motions of the Arabian and its neighboring plates are primarily based on GPS measurements obtained in the surrounding areas of the Arabian plate, with few stations actually located on the Arabian plate itself in the Kingdom of Saudi Arabia. In order to advance the knowledge of the dynamics of the Arabian plate and its intra-plate deformations, the General Directorate of Military Survey (GDMS), through collaboration with the Institute of Engineering Surveying and Space Geodesy (IESSG), densified the GPS network in Saudi Arabia, covering nearly two thirds of the tectonic plate. Since July 2002, a network of 32 GPS stations has been established at locations of the Saudi Arabia geodetic network. At all of these GPS stations a concrete pillar has been used as the monument and the locations have been selected in order to give the broadest distribution of observing sites. During 2005, 27 additional GPS stations in the Hejaz and Asser Mountains, and the Farasan Islands, all in south-western Saudi Arabia, have been established, for which the past and future campaign GPS measurements will provide valuable data for investigations of crustal deformations close to the plate boundaries between the Nubia, Somalian and Arabian plates. In this presentation we will show results in the form of velocity field and plate motion estimates based on data from at least three campaigns occupying the initial 32 GDMS GPS network stations, but also from a number of IGS stations in the region. Our reference frame is aligned to ITRF2005 and uses approximately 40 IGS reference frame stations located on all major tectonic plates, e.g. Nubia and Somalia, surrounding the Arabian plate. Furthermore, we apply absolute satellite and receiver antenna phase center models together with newly available GPS products from a recent global re-processing effort.

  17. Current Practice vs. Guideline Based Imaging in Abdominal Radiology in the German Speaking Area: Results of an Online Survey.

    Science.gov (United States)

    Schreyer, A G; Wessling, J; Grenacher, L

    2016-03-01

    The working group for abdominal imaging within the German Roentgen Society (DRG) performed an online survey amongst radiologist concerning the current status of techniques for abdominal imaging. The results of this survey were compared with the most recent guidelines. We performed an online survey open for all members of the DRG during a 76-day period with 65 questions and an overall estimated time for finishing the questionnaire of 15 minutes concerning technical specifications for abdominal radiological imaging. The results were evaluated using descriptive statistics. 90 of all participants, who filled out the survey covering more than 80% of the questions, were included in the statistical evaluation. 27% of all participants were registered radiologists while 73% represented radiologists working in a hospital. Most participants worked in a managerial position. The participants gave detailed information regarding the radiological techniques used in dedicated organ systems (esophagus, stomach, pancreas, liver, small intestines, colon) regarding acquired contrast phases and oral and intravenous administration of contrast medium. The results confirm that most radiologists participating in this survey perform their examinations and choose their modalities in conformity with the current existing clinical guidelines. Because most clinical guidelines do not specify radiological examinations in detail, there is a noteworthy heterogeneity of the acquired contrast phases and major divergence in terms of technical parameters. Therefore a joint radiological effort should be initiated for developing and publishing updated radiological parameters for abdominal imaging. • In German speaking countries indications for abdominal radiological examinations are performed with a high compliance to published guidelines. • There is a significant heterogeneity regarding the acquisition of different contrast phases for parenchymal abdominal organs. • There is an urgent need to

  18. Effect of current mode on PEO treatment of magnesium in Ca- and P-containing electrolyte and resulting coatings

    Science.gov (United States)

    Gao, Yonghao; Yerokhin, Aleksey; Matthews, Allan

    2014-10-01

    Plasma electrolytic oxidation (PEO) coatings were produced on commercially pure magnesium in a biologically friendly electrolyte composed of 2 g L-1 Ca(OH)2 and 12 g L-1 Na3PO4·12H2O using pulsed unipolar and bipolar current regimes with negative biasing varying from 0 to 20 mA cm-2. Analysis of voltage transients was performed to characterise the PEO processes. The coating morphology and phase composition were studied by scanning electron microscopy and X-ray diffraction technique, respectively. In vitro corrosion performance of the coatings was evaluated in a simulated body fluid at 37 ± 1 °C, using electrochemical techniques including open circuit potential monitoring, electrochemical impedance spectroscopy and potentiodynamic polarisation scans. The influence of the negative biasing on the PEO process and resulting coating characteristics is discussed. Unlike generally recognised beneficial effects of the negative biasing in PEO treatments of some other metal-electrolyte systems, it was found that detrimental effects are induced to the coatings on cp-Mg produced in the studied electrolyte when the negative current amplitude increases, which may be attributed to hydrogen liberation at the coating/substrate interface during the negative biasing cycles. As a result, a deterioration of vitro corrosion performance was observed for the pulsed bipolar PEO coatings compared to those produced using the pulsed unipolar regime which provides better quality coatings.

  19. Chronic ischaemic mitral regurgitation. Current treatment results and new mechanism-based surgical approaches

    NARCIS (Netherlands)

    Bouma, Wobbe; van der Horst, Iwan C. C.; Wijdh-den Hamer, Inez J.; Erasmus, Michiel E.; Zijlstra, Felix; Mariani, Massimo A.; Ebels, Tjark

    2010-01-01

    Chronic ischaemic mitral regurgitation (CIMR) remains one of the most complex and unresolved aspects in the management of ischaemic heart disease. This review provides an overview of the present knowledge about the different aspects of CIMR with an emphasis on mechanisms, current surgical treatment

  20. Experimental Results on Current-Driven Turbulence in Plasmas - a Survey

    NARCIS (Netherlands)

    Dekluiver, H.; Perepelkin, N. F.; Hirose, A.

    1991-01-01

    The experimental consequences of plasma turbulence driven by a current parallel to a magnetic field and concurrent anomalous plasma heating are reviewed, with an attempt to deduce universalities in key parameters such as the anomalous electrical conductivities observed in diverse devices. It has

  1. Blood pressure and lipid management fall far short in persons with type 2 diabetes: results from the DIAB-CORE Consortium including six German population-based studies

    Directory of Open Access Journals (Sweden)

    Rückert Ina-Maria

    2012-05-01

    Full Text Available Abstract Background Although most deaths among patients with type 2 diabetes (T2D are attributable to cardiovascular disease, modifiable cardiovascular risk factors appear to be inadequately treated in medical practice. The aim of this study was to describe hypertension, dyslipidemia and medical treatment of these conditions in a large population-based sample. Methods The present analysis was based on the DIAB-CORE project, in which data from five regional population-based studies and one nationwide German study were pooled. All studies were conducted between 1997 and 2006. We assessed the frequencies of risk factors and co-morbidities, especially hypertension and dyslipidemia, in participants with and without T2D. The odds of no or insufficient treatment and the odds of pharmacotherapy were computed using multivariable logistic regression models. Types of medication regimens were described. Results The pooled data set comprised individual data of 15, 071 participants aged 45–74 years, including 1287 (8.5% participants with T2D. Subjects with T2D were significantly more likely to have untreated or insufficiently treated hypertension, i.e. blood pressure of > = 140/90 mmHg (OR = 1.43, 95% CI 1.26-1.61 and dyslipidemia i.e. a total cholesterol/HDL-cholesterol ratio > = 5 (OR = 1.80, 95% CI 1.59-2.04 than participants without T2D. Untreated or insufficiently treated blood pressure was observed in 48.9% of participants without T2D and in 63.6% of participants with T2D. In this latter group, 28.0% did not receive anti-hypertensive medication and 72.0% were insufficiently treated. In non-T2D participants, 28.8% had untreated or insufficiently treated dyslipidemia. Of all participants with T2D 42.5% had currently elevated lipids, 80.3% of these were untreated and 19.7% were insufficiently treated. Conclusions Blood pressure and lipid management fall short especially in persons with T2D across Germany. The importance of sufficient

  2. Soil structure modeling with different correlation functions: current results and future perspectives

    Science.gov (United States)

    Karsanina, M.; Gerke, K.; Vasilyev, R.; Skvortsova, E.

    2012-04-01

    One of the main factors defining numerous flow phenomena in soils and other porous media, including fluid and solute movements, is pore structure, e.g., pore volume and its connectivity. In recent decades different numerical methods were developed to quantify single and multi-phase flow in such media on microscale. Among most popular ones are: 1) a wide range of finite difference/element/volume solutions of Navier-Stokes equations and its simplifications; 2) lattice-Boltzmann method; 3) pore-network models. Each method has some advantages and weak sides, so that different research teams usually utilize more than one, depending on the study case. Recent progress in X-ray tomography and some other techniques allows precise determination of soil three-dimensional structure, however, a trade-off between resolution and sample size is usually unavoidable. There are situations then only standard two-dimensional information of porous structure is known due to tomography high cost or resolution limitations. But physical modeling on microscale, there most interfacial processes take place requires 3D information. There are three main approaches to reconstruct (using 2D cut(s) or some other limited information/properties) porous media: 1) statistical methods (correlation functions and simulated annealing, multi-point statistics, entropy methods), 2) sequential methods (sphere or other granular packs) and 3) morphological methods. Multi-point statistical method is believed to excel others due to its simplicity with respect to practical applications and better results (in particular pore space connectivity and anisotropy issues). Recently it was shown that cluster function implication significantly improve reconstruction quality, especially in comparison with original Yeong-Torquato technique based on two-point probability and linear functions. Another possible reason for these correlation functions poorer performance is computer power limitations of that time, e.g., high energy

  3. Current Situation of AFREF and First Results from GNSS Networks in Africa

    Science.gov (United States)

    Mahmoud, Salah; Farah, Hussein; Wonnacott, Richard

    2016-07-01

    The African Geodetic Reference Frame (AFREF) is conceived as a unified geodetic reference frame for Africa. It will be the fundamental basis for the national three-dimensional reference networks fully consistent and homogeneous with the International Terrestrial Reference Frame (ITRF). When fully implemented, its backbone will consist of a network of continuous, permanent GPS stations such that a user anywhere in Africa would have free access to, and would be at most 1000km from, such stations. Full implementation will include a unified vertical datum and support for efforts to establish a precise African geoid, in concert with the African Geoid project activities. The realization of AFREF has vast potentials for geodesy, mapping, surveying, geoinformation, natural hazards mitigation, earth sciences, etc. Its implementation will provide a major springboard for the transfer and enhancement of skills in surveying and geodesy and especially GPS technology and applications. AFREF is, therefore, an African initiative to unify the geodetic reference frames of Africa based on the ITRF through a network of GNSS base stations at a spacing such users will be at most within ~1000 km of a base station. First Reference Frame Solution of about 80 geodetic GPS stations in Africa has been started in February 2013 at some processing centers in Europe and Africa. Results of independent solutions being developed by various African scientific teams: Hart RAO, South Africa; Ardhi University, Tanzania and SEGAL, University of Beria Interior, Portugal, show an accuracy of aligned ITRF 2008 using 42 IGS stations in E and N components with 3.0 mm and in U component 7.5 mm.

  4. Current research and future directions in pattern identification: Results of an international symposium.

    Science.gov (United States)

    Lee, Myeong Soo; Lee, Ju Ah; Alraek, Terje; Bian, Zhao-Xiang; Birch, Stephen; Goto, Hirozo; Jung, Jeeyoun; Kao, Shung-Te; Moon, Sang-Kwan; Park, Bongki; Park, Kyung-Mo; You, Sooseong; Yun, Kyung-Jin; Zaslawski, Chris

    2016-12-01

    A symposium on pattern identification (PI) was held at the Korea Institute of Oriental Medicine (KIOM) on October 2, 2013, in Daejeon, South Korea. This symposium was convened to provide information on the current research in PI as well as suggest future research directions. The participants discussed the nature of PI, possible research questions, strategies and future international collaborations in pattern research. With eight presentations and an extensive panel discussion, the symposium allowed participants to discuss research methods in traditional medicine for PI. One speaker presented the topic, 'Clinical pattern differentiation and contemporary research in PI.' Two speakers presented current trends in research on blood stasis while the remaining five other delegates discussed the research methods and future directions of PI research. The participants engaged in in-depth discussions regarding the nature of PI, potential research questions, strategies and future international collaborations in pattern research.

  5. Elbow hemiarthroplasty for the management of distal humeral fractures: current technique, indications and results

    OpenAIRE

    Phadnis, Joideep; Adam C. Watts; Bain, Gregory I

    2016-01-01

    There has been a growing recent interest in the use of elbow hemiarthroplasty for the treatment of distal humeral trauma in select patients. However, the current available evidence regarding outcome after elbow hemiarthroplasty is limited to case series and biomechanical data. Consequently, the procedure remains unfamiliar to many surgeons. The aim of the present review is to outline the evidence regarding elbow hemiarthroplasty and to use this, along with the author’s experience, to better d...

  6. Pseudo-2D polarization model of polymer exchange membrane fuel cell including mass transport limitation due to flooding : numerical simulation and comparison with experimental results

    Energy Technology Data Exchange (ETDEWEB)

    Maranzana, G.; Chupin, S.; Colinart, T.; Lottin, O.; Didierjean, S. [Nancy-Univ., Vandoeuvre (France). Laboratoire d' Energetique et de Mecanique Theorique et Appliquee

    2007-07-01

    The electrodes of proton membrane exchange (PEM) fuel cells are fed by gases, whose properties are changing during their transition from the inlet to the outlet of the channels. For example, the reactant concentration decreases and the water concentration increases, the total pressure diminishes, the temperature is dependent on the local current density, and liquid water may appear or disappear. The electrode performances are not uniform, which can have impacts on the entire performances of the cell or on its durability. In order to observe and model these non-homogeneities, this paper presented an experimental study that involved designing, building, and testing a single PEM fuel cell that allowed measurement of both current density and temperature fields along the gas channels. The fuel cell was made of transparent polymethyl methacrylate (PMMA) so that the location of liquid water appearance in the channels could be observed. The first experimental results were compared with the predictions of a pseudo-2D model which assumed mass transfer to occur in the direction perpendicular to the membrane, but took into account the variations in concentrations, in total pressure, and in temperatures along the gas channels. It was concluded that the current density distribution depended greatly on water management. 10 refs., 3 figs.

  7. Compendium of Current Total Ionizing Dose and Displacement Damage Results from NASA GSFC and NEPP

    Science.gov (United States)

    Topper, Alyson D.; Campola, Michael J.; Chen, Dakai; Casey, Megan C.; Yau, Ka-Yen; Label, Kenneth A.; Cochran, Donna J.; O'Bryan, Martha V.

    2017-01-01

    Total ionizing dose and displacement damage testing was performed to characterize and determine the suitability of candidate electronics for NASA space utilization. Devices tested include opto-electronics, digital, analog, linear bipolar devices, and hybrid devices.

  8. Age at menarche and current substance use among Canadian adolescent girls: results of a cross-sectional study

    Directory of Open Access Journals (Sweden)

    Al-Sahab Ban

    2012-03-01

    Full Text Available Abstract Background Substance use is among the key public health threats that find its genesis during adolescence. Timing of puberty has been lately researched as a potential predictor of subsequent substance abuse. The present study, therefore, aims to assess the effect of age at menarche on current practices of smoking, alcohol drinking and drug use among 14-15 year old Canadian girls. Methods The analysis of the study was based on all female respondents aged 14 to 15 years during Cycle 4 (2000/2001 of the National Longitudinal Survey of Children & Youth (NLSCY. The main independent variable was age at menarche assessed as the month and year of the occurrence of the first menstrual cycle. The dependent variables were current smoking, heavy alcohol drinking in the past 12 months and drug use in the past 12 months. Three logistic regression models were performed to investigate the association between age at menarche and each of the substance use outcomes, adjusting for possible confounders. Bootstrapping was performed to account for the complex sampling design. Results The total weighted sample included in the analysis represented 295,042 Canadian girls. The prevalence of current smokers, heavy drinkers (drunk in the past 12 months and drug users in the past 12 months was approximately 22%, 38% and 26%, respectively. After adjusting of all potential confounders, no association was found between age at menarche and any of the substance use outcomes. School performance and relationship with the father, however, stood out as the main variables to be associated with smoking, heavy drinking and drug use. Conclusions Qualitative studies understanding the social and psychological changes experienced by early maturing Canadian adolescents are warranted to identify other correlates or pathways to substance use in this higher risk population.

  9. Hydrodynamic processes, velocity structure and stratification in natural turbidity currents: Results inferred from field data in the Var Turbidite System

    Science.gov (United States)

    Migeon, Sébastien; Mulder, Thierry; Savoye, Bruno; Sage, Françoise

    2012-03-01

    The Var Turbidite System (NW Mediterranean Sea) is fed during the present-day highstand sea level by large earthquake-induced ignitive turbidity currents, low-density turbidity currents resulting from retrogressive failures triggered on the upper continental slope, and hyperpycnal flows related to the Var River floods. Using a large dataset including bathymetric data, side-scan sonar images, seismic-reflection profiles, cores and photographs of the seafloor, this paper attempts to better constrain the hydrodynamic behaviour of debris flows and turbidity currents along the Upper and Middle Valley of the Var Turbidite System. The drastic change of the seafloor morphology between the Upper and the Middle Valley suggests that gravity flows undergo rapid transformation from cohesive to fully turbulent behaviour. This transformation is related to a hydraulic jump caused by an abrupt decrease in slope angle at the transition between the Upper and the Middle Valley and is associated with en masse deposition and elevation of the seafloor. Strong seafloor erosion prevails in the Middle Valley, suggesting that, for a low and constant slope angle, turbulent flows must regain a balance between concentration and flow thickness rapidly after they experience hydraulic jump. The internal stratification and vertical grain-size distribution within turbulent flows are inferred from the distribution of fine- to coarse-grained turbidites found in cores located along the crest of the Var Sedimentary Ridge with a decreasing elevation above the floor of the Middle Valley. The theoretical vertical velocity profile deduced from the vertical grain-size distribution exhibits a general trend and an inflection of the gradient curve different from those of the velocity profiles classically obtained using numerical modelling.

  10. Test beam results of a heavily irradiated Current Injected Detector (CID)

    CERN Document Server

    Harkonen, J; Tuominen, E; Moilanen, H; Maenpaa, T; Verbitskaya, E; Eremin, V; Czellar, S; Dierlamm, A; Tuovinen, E; Lampen, T; Frey, M; Li, Z; Luukka, P

    2010-01-01

    A heavily irradiated (3 x 10(15) 1 MeV n(eq)/cm(2)) Current Injected Detector (CID) was tested with 225 GeV muon beam at CERN H2 beam line. In the CID concept the current is limited by the space charge. The injected carriers will be trapped by the deep levels and this induces a stable electric field through the entire bulk regardless of the irradiation fluence the detector has been exposed to. The steady-state density of the trapped charge is defined by the balance between the trapping and the emission rates of charge carriers (detrapping). Thus, the amount of charge injection needed for the electric field stabilization depends on the temperature. AC-coupled 16 cm(2) detector was processed on high resistivity n-type magnetic Czochralski silicon, and it had 768 strips, 50 mu m pitch, 10 mu m strip width and 3.9 cm strip length. The beam test was carried out using a silicon beam telescope that is based on the CMS detector readout prototype components, APV25 readout chips, and eight strip sensors made by Hamamat...

  11. MIXED FINITE ELEMENT METHODS FOR THE SHALLOW WATER EQUATIONS INCLUDING CURRENT AND SILT SEDIMENTATION ( Ⅱ )-THE DISCRETE-TIME CASE ALONG CHARACTERISTICS

    Institute of Scientific and Technical Information of China (English)

    罗振东; 朱江; 曾庆存; 谢正辉

    2004-01-01

    The mixed finite element (MFE) methods for a shallow water equation system consisting of water dynamics equations, silt transport equation, and the equation of bottom topography change were derived. A fully discrete MFE scheme for the discrete-time along characteristics is presented and error estimates are established. The existence and convergence of MFE solution of the discrete current velocity, elevation of the bottom topography, thickness of fluid column, and mass rate of sediment is demonstrated.

  12. Current practices in percutaneous nephrolithotomy in Mexico: results of a nation-wide electronic survey.

    Science.gov (United States)

    Sandoval, Christian I Villeda; Roca, Benjamin E Montaño; Molina, Ricardo A Castillejos; Mendez-Probst, Carlos E

    2015-11-01

    Practice patterns and choice of technological instruments in PCNL are not always standardized. There are no previous reports on the PCNL practice tendencies and patterns in Latin America. The aim of the study is to describe the current practice patterns of PCNL among the members of the Mexican Society of Urology ("Sociedad Mexicana de Urologia"). Observational and descriptive study. A 9-item closed questionnaire on PCNL practice patterns was answered by members of the Mexican Society of Urology in a secure website hosted survey after e-mail invitation. A descriptive numerical and graphical analysis was performed. A total of 90 contestants were registered out of 492 potential participants. PCNL is performed by 80% of the participants, with an average of 16 procedures per year. Percutaneous tracts are commonly obtained by urologists on the same day of the procedure. Sequential and telescopic dilators are equally preferred over balloons. The pneumatic litotriptor is the most common choice and CT scan and X-ray are equally used as follow-up. The practice patterns of PCNL from Mexican urologists are different from other international reports. Influence of socio-economic circumstances is inferred.

  13. Current inverter interferences - test results of the SIDENA research project; Wechselrichterwechselwirkungen - Testergebnisse aus dem Forschungsprojekt SIDENA

    Energy Technology Data Exchange (ETDEWEB)

    Bendel, C.; Funtan, P.; Kirchhof, J.; Nestle, D. [Institut fuer Solare Energieversorgungstechnik (ISET), Kassel (Germany)

    2004-07-01

    Integration of decentral power supply systems in the electricity grid requires new safety and availability problems. The SIDENA project investigated interferences at the connection point and tested the integration of, at present, a maximum of 22 PV current inverters both on the AC and on the DC side. (orig.) [German] Mit zunehmender Einbindung von dezentralen netzgekoppelten Energieerzeugungsanlagen (DEA), z.B. PV-Anlagen, BHKW's, Brennstoffzellen u.a. in das elektrische Energieversorgungsnetz muessen die Fragen der Personen- und Anlagensicherheit sowie der Netzzuverlaessigkeit und -qualitaet neu ueberdacht werden. Die dezentralen Energieerzeugungsanlagen (DEA), die beispielhaft ueber Wechselrichter ins oeffentliche Netz einspeisen, verursachen und erfahren Wirkungen an der Netzanschlussstelle, deren stoerende Ursachen zu klaeren sind. Bei diesen stoerenden Ursachen handelt es sich um Kompatibilitaetsprobleme der Netzabschalteinrichtungen (ENS) zum Netz, aber auch bei groesserer Anzahl an einem Netzanschlusspunkt untereinander. Die nachteiligen Wirkungen sind in der Mehrzahl zu haeufige unbegruendete Abschaltungen und damit eine unzuverlaessige Betriebsweise. Bei einer hoeheren Durchdringung der Netze mit DEA ist das von zunehmender Bedeutung. Im Rahmen des Projektes SIDENA ('Sicherheitsaspekte bei dezentralen netzgekoppelten Energieerzeugungsanlagen') werden daher unterschiedliche Wechselwirkungen am Netzanschlusspunkt untersucht und der Betrieb von derzeitig max. 22 PV-Wechselrichtern sowohl AC- als auch DC-seitig geprueft. (orig.)

  14. Overview of HIT-SI3 experiment: Simulations, Diagnostics, and Summary of Current Results

    Science.gov (United States)

    Penna, James; Jarboe, Thomas; Nelson, Brian; Hossack, Aaron; Sutherland, Derek; Morgan, Kyle; Hansen, Chris; Benedett, Thomas; Everson, Chris; Victor, Brian

    2016-10-01

    The Helicity Injected Torus - Steady Inductive 3(HIT-SI3)experiment forms and maintains spheromaks via Steady Inductive Helicity Injection (SIHI). Three injector units allow for continuous injection of helicity into a copper flux conserver in order to sustain a spheromak. Firing of the injectors with a phase difference allows finite rotation of the plasma to provide a stabilizing effect. Simulations in the MHD code NIMROD and the fluid-model code PSI-TET provide validation and a basis for interpretation of the observed experimental data. Thompson Scattering (TS) and Far Infrared (FIR) Interferometer systems allow temperature and line-averaged density measurements to be taken. An Ion Doppler Spectroscopy (IDS) system allows measurement of the plasma rotation and velocity. HIT-SI3 data has been used for validation of IDCD predictions, in particular the projected impedance of helicity injectors according to the theory. The experimental impedances have been calculated here for the first time for different HIT-SI3 regimes. Such experimental evidence will contribute to the design of future experiments employing IDCD as a current-drive mechanism. Work supported by the D.O.E., Office of Science, Office of Fusion Science.

  15. "Amazing Space": Creating Educational Resources from Current Scientific Research Results from the Hubble Space Telescope.

    Science.gov (United States)

    Christian, C. A.; Eisenhamer, B.; Eisenhamer, Jonathan; Teays, Terry

    2001-01-01

    Introduces the Amazing Space program which is designed to enhance student mathematics, science, and technology skills using recent data and results from the National Aeronautics and Space Administration's (NASA) Hubble Space Telescope mission. Explains the process of designing multi-media resources in a five-week summer workshop that partners…

  16. Current trends of management of respiratory diseases by pulmonologists: Results of National Conference of Pulmonary Disease - 2015 survey

    Directory of Open Access Journals (Sweden)

    Sheetu Singh

    2017-01-01

    Full Text Available Context: Respiratory diseases are a common problem in our country and these are associated with significant morbidity and mortality. Aims: The aim of the paper was to analyze the pattern of diagnostic tests used and treatment prescribed for common respiratory diseases. Settings and Design: A total of 1028 pulmonologists, either member of Indian Chest Society or delegate attending the National Conference of Pulmonary Diseases (NAPCON 2015, participated in the online survey. Subjects and Methods: The survey included questions pertinent to common respiratory diseases such as pulmonary tuberculosis (PTB, bronchial asthma, chronic obstructive pulmonary disease (COPD, idiopathic pulmonary fibrosis (IPF, and pneumonia. Results: Investigation used for severity assessment and diagnosis of PTB, was sputum for acid-fast bacilli (83.5%, for IPF was high-resolution computed tomography chest (85.6%, for severe pneumonia was arterial blood gas analysis (69.3%, for asthma was spirometery and peak flow (96.8% and for COPDs was spirometry (87.2%. The most popular choice of treatment for PTB was directly observed treatment short course (55.7%, for bronchial asthma, it was long-acting beta agonist with inhaled corticosteroids (LABA + ICSs (41.1%, for COPD, it was LABA, ICS, and long-acting muscarinic antagonist (LABA + ICS + long-acting muscarinic antagonist (32.4% and for IPF, it was pirfenidone and N acetyl cysteine (38.3%. About 67.5% of doctors preferred hospitalization for patients with severe pneumonia. About 84.5% pulmonologists ordered diagnostic tests and 55.5% prescribed treatment as per current guidelines. Conclusions: The majority of doctors (70.1% in our survey followed recommended guidelines for respiratory disease diagnosis and treatment. However, there is a need for upgradation of treatment strategies currently used by doctors.

  17. Current trends of management of respiratory diseases by pulmonologists: Results of National Conference of Pulmonary Disease - 2015 survey

    Science.gov (United States)

    Singh, Sheetu; Singh, Nishtha

    2017-01-01

    Context: Respiratory diseases are a common problem in our country and these are associated with significant morbidity and mortality. Aims: The aim of the paper was to analyze the pattern of diagnostic tests used and treatment prescribed for common respiratory diseases. Settings and Design: A total of 1028 pulmonologists, either member of Indian Chest Society or delegate attending the National Conference of Pulmonary Diseases (NAPCON) 2015, participated in the online survey. Subjects and Methods: The survey included questions pertinent to common respiratory diseases such as pulmonary tuberculosis (PTB), bronchial asthma, chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), and pneumonia. Results: Investigation used for severity assessment and diagnosis of PTB, was sputum for acid-fast bacilli (83.5%), for IPF was high-resolution computed tomography chest (85.6%), for severe pneumonia was arterial blood gas analysis (69.3%), for asthma was spirometery and peak flow (96.8%) and for COPDs was spirometry (87.2%). The most popular choice of treatment for PTB was directly observed treatment short course (55.7%), for bronchial asthma, it was long-acting beta agonist with inhaled corticosteroids (LABA + ICSs) (41.1%), for COPD, it was LABA, ICS, and long-acting muscarinic antagonist (LABA + ICS + long-acting muscarinic antagonist) (32.4%) and for IPF, it was pirfenidone and N acetyl cysteine (38.3%). About 67.5% of doctors preferred hospitalization for patients with severe pneumonia. About 84.5% pulmonologists ordered diagnostic tests and 55.5% prescribed treatment as per current guidelines. Conclusions: The majority of doctors (70.1%) in our survey followed recommended guidelines for respiratory disease diagnosis and treatment. However, there is a need for upgradation of treatment strategies currently used by doctors. PMID:28144054

  18. The prevalence of chromium allergy in Denmark is currently increasing as a result of leather exposure

    DEFF Research Database (Denmark)

    Thyssen, J P; Jensen, P; Carlsen, B C;

    2009-01-01

    previously been demonstrated among Danish construction workers. OBJECTIVES: To investigate the development of chromium allergy among patients with dermatitis tested between 1985 and 2007 in Denmark. Furthermore, to determine causative exposures in patients with chromium allergy. PATIENTS AND METHODS......: A retrospective analysis of patch test data was performed (n = 16,228) and charts from patients with chromium allergy were reviewed. Comparisons were made using a chi(2) test. Logistic regression analyses were used to test for associations. RESULTS: The prevalence of chromium allergy decreased significantly from...

  19. Large A.C. machines theory and investigation methods of currents and losses in stator and rotor meshes including operation with nonlinear loads

    CERN Document Server

    Boguslawsky, Iliya; Hayakawa, Masashi

    2017-01-01

    In this monograph the authors solve the modern scientific problems connected with A.C. motors and generators, based first on the detailed consideration of their physical phenomena. The authors describe the theory and investigative methods they developed and applied in practice, which are considered to be of essential interest for specialists in the field of the electrical engineering industry in European countries, the USA, Argentina, and Brazil, as well as in such countries as India, China, and Iran. This book will be of interest to engineers specialized in the field of the manufacture, operation, and repair of A.C. machines (motors and generators) as well as electric drives; to professors, lecturers, and post-graduate students of technical universities, who are specializing in the field of electric machine engineering and electric drives; and to students who are engaged in the field of high current techniques, electric drives, and electric machine engineering.

  20. ADVANCED SIMULATION CAPABILITY FOR ENVIRONMENTAL MANAGEMENT- CURRENT STATUS AND PHASE II DEMONSTRATION RESULTS

    Energy Technology Data Exchange (ETDEWEB)

    Seitz, R.

    2013-02-26

    The U.S. Department of Energy (USDOE) Office of Environmental Management (EM), Office of Soil and Groundwater, is supporting development of the Advanced Simulation Capability for Environmental Management (ASCEM). ASCEM is a state-of-the-art scientific tool and approach for understanding and predicting contaminant fate and transport in natural and engineered systems. The modular and open source high-performance computing tool facilitates integrated approaches to modeling and site characterization that enable robust and standardized assessments of performance and risk for EM cleanup and closure activities. The ASCEM project continues to make significant progress in development of computer software capabilities with an emphasis on integration of capabilities in FY12. Capability development is occurring for both the Platform and Integrated Toolsets and High-Performance Computing (HPC) Multiprocess Simulator. The Platform capabilities provide the user interface and tools for end-to-end model development, starting with definition of the conceptual model, management of data for model input, model calibration and uncertainty analysis, and processing of model output, including visualization. The HPC capabilities target increased functionality of process model representations, toolsets for interaction with Platform, and verification and model confidence testing. The Platform and HPC capabilities are being tested and evaluated for EM applications in a set of demonstrations as part of Site Applications Thrust Area activities. The Phase I demonstration focusing on individual capabilities of the initial toolsets was completed in 2010. The Phase II demonstration completed in 2012 focused on showcasing integrated ASCEM capabilities. For Phase II, the Hanford Site deep vadose zone (BC Cribs) served as an application site for an end-to-end demonstration of capabilities, with emphasis on integration and linkages between the Platform and HPC components. Other demonstrations

  1. Late radiation responses in man: Current evaluation from results from Hiroshima and Nagasaki

    Science.gov (United States)

    Schull, William J.

    Among the late effects of exposure to the atomic bombings of Hiroshima and Nagasaki, none looms larger than radiation related malignancies. Indeed, the late effects of A-bomb radiation on mortality appear to be limited to an increase in malignant tumors. At present, it can be shown that cancers of the breast, colon, esophagus, lungs, stomach, thyroid, and urinary tract as well as leukemia and multiple myeloma increase in frequency with an increase in exposure. No significant relationship to radiation can as yet be established for malignant lymphoma, nor cancers of the rectum, pancreas or uterus. Radiation induced malignancies other than leukemia seem to develop proportionally to the natural cancer rate for the attained age. For specific age-at-death intervals, both relative and absolute risks tend to be higher for those of younger age at the time of bombing. Other late effects include radiation-related lenticular opacities, disturbances of growth among those survivors still growing at the time of exposure, and mental retardation and small head sizes among the in utero exposed. Chromosomal abnormalities too are more frequently encountered in the peripheral leucocytes of survivors, and this increase is functionally related to their exposure. Some uncertainty continues to surround both the quantity and quality of the radiation released by these two nuclear devices, particularly the Hiroshima bomb. A recent reassessment suggests that the gamma radiation estimates which have been used in the past may be too low at some distances and the neutron radiation estimates too high at all distances; moreover, the energies of the neutrons released now appear ``softer'' than previously conjectured. These uncertainties not sufficiently large, however, to compromise the reality of the increased frequency of malignancy, but make estimates of the dose response, particularly in terms of gamma and neutron exposures, tentative.

  2. Behavior of a DC zero-flux current sensor; Magnetic field analysis and comparison with experimental results

    Energy Technology Data Exchange (ETDEWEB)

    Campostrini, P.; Sonato, P. (Istituto Gas Ionizzati del CNR, Padova (IT))

    1991-09-01

    In this paper the magnetic section of the finite-element ANSYS code, and in particular its optimization feature has been used to predict the behaviour of a zero-flux current sensor, briefly described, which is intended to be used in a fusion experiment to measure pulsed currents up to 50 kA, over a bandwidth from DC to 10 k Hz. The computed results fit well with those coming from experimental tests performed on a prototype.

  3. High-resolution ionospheric observations and modeling over Belgium during the solar eclipse of 20 March 2015 including first results of ionospheric tilt and plasma drift measurements

    Science.gov (United States)

    Verhulst, Tobias G. W.; Sapundjiev, Danislav; Stankov, Stanimir M.

    2016-06-01

    The ionospheric behavior over Belgium during the partial solar eclipse of 20 March 2015 is analyzed based on high-resolution solar radio flux, vertical incidence sounding, and GPS TEC measurements. First results of ionosonde-based ionospheric plasma drift and tilt observations are presented and analyzed, including some traveling ionospheric disturbances caused by the eclipse. Also, collocated ionosonde and GPS measurements are used to reconstruct the time evolution of the vertical electron density distribution using the Royal Meteorological Institute (RMI) ionospheric specification system, called Local Ionospheric Electron Density profile Reconstruction (LIEDR).

  4. Results of operation and current safety performance of nuclear facilities located in the Russian Federation

    Science.gov (United States)

    Kuznetsov, V. M.; Khvostova, M. S.

    2016-12-01

    After the NPP radiation accidents in Russia and Japan, a safety statu of Russian nuclear power plants causes concern. A repeated life time extension of power unit reactor plants, designed at the dawn of the nuclear power engineering in the Soviet Union, power augmentation of the plants to 104-109%, operation of power units in a daily power mode in the range of 100-70-100%, the use of untypical for NPP remixed nuclear fuel without a careful study of the results of its application (at least after two operating periods of the research nuclear installations), the aging of operating personnel, and many other management actions of the State Corporation "Rosatom", should attract the attention of the Federal Service for Ecological, Technical and Atomic Supervision (RosTekhNadzor), but this doesn't happen. The paper considers safety issues of nuclear power plants operating in the Russian Federation. The authors collected statistical information on violations in NPP operation over the past 25 years, which shows that even after repeated relaxation over this period of time of safety regulation requirements in nuclear industry and highly expensive NPP modernization, the latter have not become more safe, and the statistics confirms this. At a lower utilization factor high-power pressure-tube reactors RBMK-1000, compared to light water reactors VVER-440 and 1000, have a greater number of violations and that after annual overhauls. A number of direct and root causes of NPP mulfunctions is still high and remains stable for decades. The paper reveals bottlenecks in ensuring nuclear and radiation safety of nuclear facilities. Main outstanding issues on the storage of spent nuclear fuel are defined. Information on emissions and discharges of radioactive substances, as well as fullness of storages of solid and liquid radioactive waste, located at the NPP sites are presented. Russian NPPs stress test results are submitted, as well as data on the coming removal from operation of NPP

  5. Myocardial perfusion scintigraphy in Germany. Results of the 2005 query and current status

    Energy Technology Data Exchange (ETDEWEB)

    Lindner, O. [Inst. fuer Radiologie, Nuklearmedizin und Molekulare Bildgebung, Herz- und Diabeteszentrum NRW, Bad Oeynhausen (Germany); Burchert, W. [Inst. fuer Radiologie, Nuklearmedizin und Molekulare Bildgebung, Herz- und Diabeteszentrum NRW, Bad Oeynhausen (Germany); Arbeitsgemeinschaft ' ' Kardiovaskulaere Nuklearmedizin' ' der Deutschen Gesellschaft fuer Nuklearmedizin (Germany); Bengel, F.M. [Cardiovascular Nuclear Medicine, Johns Hopkins Medical Insts., Baltimore (United States); Arbeitsgruppe ' ' Nuklearkardiologische Diagnostik' ' der Deutschen Gesellschaft fuer Kardiologie (Germany); Zimmermann, R. [Arbeitsgruppe ' ' Nuklearkardiologische Diagnostik' ' der Deutschen Gesellschaft fuer Kardiologie (Germany); Medizinische Klinik, Klinikum Pforzheim GmbH (Germany); Dahl, J. vom [Klinik fuer Kardiologie, Kliniken Maria Hilf GmbH, Moenchengladbach (Germany); Schaefer, W.; Buell, U. [Klinik fuer Nuklearmedizin, Universitaetsklinikum Aachen (Germany); Schober, O. [Klinik und Poliklinik fuer Nuklearmedizin, Universitaetsklinikum Muenster (Germany); Schwaiger, M. [Nuklearmedizinische Klinik, Klinikum Rechts der Isar, Muenchen (Germany); Kluge, R. [Klinik und Poliklinik fuer Nuklearmedizin, Univ. Leipzig (Germany); Schaefers, M. [Arbeitsgemeinschaft ' ' Kardiovaskulaere Nuklearmedizin' ' der Deutschen Gesellschaft fuer Nuklearmedizin (Germany); Klinik und Poliklinik fuer Nuklearmedizin, Universitaetsklinikum Muenster (Germany)

    2007-07-01

    The working group Cardiovascular Nuclear Medicine of the German Society of Nuclear Medicine (DGN), in cooperation with the working group Nuclear Cardiology of the German Cardiac Society (DGK), decided to conduct a national survey on myocardial perfusion scintigraphy (MPS). Method: a questionnaire to evaluate MPS for the year 2005 was sent. Results: 346 completed questionnaires had been returned (213 private practices, 99 hospitals and 33 university hospitals). MPS of 112 707 patients were reported with 110 747 stress and 95 878 rest studies. The majority (> 75%) was performed with {sup 99m}Tc-MIBI or tetrofosmin. {sup 201}Tl stress-redistribution was used in 22 637 patients (20%). The types of stress were exercise in 78%, vasodilation with adenosine or dipyridamol in 21% and dobutamine in 1%. 99.97% of all MPS were SPECT studies. Gated SPECT was performed in 36% of the stress and in 32% of the rest studies. An attenuation correction was used in 21%. 29 institutions (8%) performed gated SPECT (stress and rest) and attenuation correction. 47% of all MPS were requested by ambulatory care cardiologists, 17% by internists, 12% by primary care physicians, 21% by hospital departments and 2% by others. Conclusion: in Germany, MPS is predominantly performed with {sup 99m}Tc-perfusion agents. The common type of stress is ergometry. Gated SPECT and attenuation correction do not yet represent standards of MPS practice in Germany, which indicates some potential of optimization. (orig.)

  6. Myocardial perfusion scintigraphy 2007 in Germany. Results of the query and current status

    Energy Technology Data Exchange (ETDEWEB)

    Lindner, O. [Inst. fuer Radiologie, Nuklearmedizin und Molekulare Bildgebung, Herz- und Diabeteszentrum NRW, Bad Oeynhausen (Germany); Burchert, W. [Inst. fuer Radiologie, Nuklearmedizin und Molekulare Bildgebung, Herz- und Diabeteszentrum NRW, Bad Oeynhausen (Germany); Arbeitsgemeinschaft Kardiovaskulaere Nuklearmedizin der Deutschen Gesellschaft fuer Nuklearmedizin (Germany); Bengel, F.M. [Cardiovascular Nuclear Medicine, Johns Hopkins Medical Institutions, Baltimore (United States); Arbeitsgruppe Nuklearkardiologische Diagnostik der Deutschen Gesellschaft fuer Kardiologie (Germany); Zimmermann, R. [Arbeitsgruppe Nuklearkardiologische Diagnostik der Deutschen Gesellschaft fuer Kardiologie (Germany); Medizinische Klinik, Klinikum Pforzheim GmbH, Pforzheim (Germany); Dahl, J. vom [Klinik fuer Kardiologie, Kliniken Maria Hilf GmbH, Moenchengladbach (Germany); Schaefer, W. [Klinik fuer Nuklearmedizin, Universitaetsklinikum Aachen (Germany); Schober, O. [Klinik und Poliklinik fuer Nuklearmedizin, Universitaetsklinikum Muenster UKM (Germany); Schaefers, M. [Arbeitsgemeinschaft Kardiovaskulaere Nuklearmedizin der Deutschen Gesellschaft fuer Nuklearmedizin (Germany); Klinik und Poliklinik fuer Nuklearmedizin, Universitaetsklinikum Muenster UKM (Germany)

    2009-07-01

    Aim: This third survey of the working group Cardiovascular Nuclear Medicine of the German Society of Nuclear Medicine in cooperation with the working group Nuclear Cardiology of the German Cardiac Society was to deliver information on the procedures and in particular on the development of myocardial perfusion scintigraphy (MPS) from 2005 to 2007. Method: 370 questionnaires (222 private practices (PP), 117 hospitals (HO), 31 university hospitals (UH)) were evaluated. Results: MPS of 114,374 patients were reported, 83% were investigated with {sup 99m}Tc-perfusion tracers. 76% [2006=74%] were performed in PP, 15% [2006=17%] in HO and 9% [2006=9%] in UH. Diabetics represented 21% of all MPS patients in 2007. Data of 215 institutions which participated all from 2005 to 2007 showed an increase in MPS of 2.3% (PP +6.8%, HO -4.5%, UH -18.2%). The type of stress was pharmacological in 27% [2006 = 27%]; 67% adenosine (of these 25% with exercise), 31% dipyridamole (of these 55% with exercise), and 2% dobutamine. Gated SPECT was performed in 47% [2006 = 42%] of all rest and in 44% [2006 = 39%] of all stress MPS. 61% [2006 = 83%] of all institutions did not apply perfusion scores. 20% [2006 = 24%] of the institutions reported changes in the use of MPS by competing methods. Conclusion: There is a small increase of MPS between 2005 and 2007 despite competing methods. Gated SPECT has experienced more acceptance, but is still underrepresented. As compared to the European average and general standards of MPS a considerable backlog accounts to pharmacological stress tests, gated SPECT and perfusion scores. (orig.)

  7. Contact allergy to fragrances: current patch test results (2005-2008) from the Information Network of Departments of Dermatology.

    Science.gov (United States)

    Uter, Wolfgang; Geier, Johannes; Frosch, Peter; Schnuch, Axel

    2010-11-01

    Contact sensitization to fragrances is common both in clinical and in population samples. The spectrum of allergens is broad and diverse, and to some extent covered by a set of screening agents. To examine the current frequency of contact sensitization to fragrance allergens in patients routinely patch tested for suspected allergic contact dermatitis with the baseline series and special series. Between 2005 and 2008, 40 709 patients were patch tested in the departments of the Information Network of Departments of Dermatology (http://www.ivdk.org). Results with selected fragrances were analysed. Of all patients tested with the German baseline series, 15.1% reacted positively to fragrance mix (FM) I (6.6% positive), FM II (4.6% positive) or Myroxylon pereirae resin (balsam of Peru, 6.8% positive). Among the single constituents of FM I, Evernia prunastri [oak moss absolute (abs.)] was the leading allergen, and amyl cinnamal the least frequent allergen. Among fragrances not included in FM I or FM II, Evernia furfuracea (tree moss abs.) was the most common allergen. For diagnostic purposes, it is necessary to combine several screening agents. The frequency of contact sensitization differs greatly between single fragrances. © 2010 John Wiley & Sons A/S.

  8. Current regimen of pulse therapy for pemphigus: Minor modifications, improved results

    Directory of Open Access Journals (Sweden)

    Pasricha J

    2008-01-01

    Full Text Available Background: If administered properly, dexamethasone cyclophosphamide pulse (DCP therapy has the potential to effect lifelong recovery from pemphigus. Aims: The objective of this paper is to highlight various parameters of DCP therapy and also, to report the effects of a few modifications in the regimen. Methods: An analysis of 123 patients treated with the DCP/DP regimen over a period of five years (1998 to 2002 is presented here. Seventeen patients who did not start/continue the treatment and three patients who died during the treatment have been excluded from the analysis. Twenty patients who had not yet started families were given only dexamethasone pulses (DPs while 103 patients received DCPs. Low dose (50 mg/day cyclophosphamide was used as in the standard regimen. The three modifications introduced into the regimen were: (1 an additional daily dose of oral betamethasone sufficient to control the disease activity during phase I, which was progressively tapered off completely as the patient recovered, (2 use of systemic antibiotics if the patient had skin lesions, and oral anti-candida drugs if the patient had oral ulcers until complete healing, and (3 insistence on thorough cleaning of the skin and scalp with a normal soap and shampoo, and proper maintenance of oral hygiene in spite of skin/mucosal lesions. The regimen consisted of DCP/DP repeated in exactly 28-day cycles, along with 50 mg cyclophosphamide per day, insistence on completing the treatment and avoiding irregular pulses in all patients. The number of DCPs/DPs during phase I varied in different patients depending upon the dose of betamethasone used and the rate of recovery, but phase II (nine DCPs/DPs in exactly 28-day cycles along with 50 mg cyclophosphamide per day and phase III (only 50 mg cyclophosphamide per day was fixed at nine months each. This was followed by posttreatment follow-up (phase IV. Results: At present, all the patients are in complete remission. The

  9. Treating axial and peripheral spondyloarthritis, including psoriatic arthritis, to target: results of a systematic literature search to support an international treat-to-target recommendation in spondyloarthritis

    Science.gov (United States)

    Schoels, M M; Braun, J; Dougados, M; Emery, P; Fitzgerald, O; Kavanaugh, A; Kvien, T K; Landewé, R; Luger, T; Mease, P; Olivieri, I; Reveille, J; Ritchlin, C; Rudwaleit, M; Sieper, J; Smolen, J S; de Wit, M; van der Heijde, D

    2014-01-01

    Background Current recommendations for the management of axial spondyloarthritis (SpA) and psoriatic arthritis are to monitor disease activity and adjust therapy accordingly. However, treatment targets and timeframes of change have not been defined. An international expert panel has been convened to develop ‘treat-to-target’ recommendations, based on published evidence and expert opinion. Objective To review evidence on targeted treatment for axial and peripheral SpA, as well as for psoriatic skin disease. Methods We performed a systematic literature search covering Medline, Embase and Cochrane, conference abstracts and studies in http://www.clinicaltrials.gov. Results Randomised comparisons of targeted versus routine treatment are lacking. Some studies implemented treatment targets before escalating therapy: in ankylosing spondylitis, most trials used a decrease in Bath Ankylosing Spondylitis Disease Activity Index; in psoriatic arthritis, protocols primarily considered a reduction in swollen and tender joints; in psoriasis, the Modified Psoriasis Severity Score and the Psoriasis Area and Severity Index were used. Complementary evidence correlating these factors with function and radiographic damage at follow-up is sparse and equivocal. Conclusions There is a need for randomised trials that investigate the value of treat-to-target recommendations in SpA and psoriasis. Several trials have used thresholds of disease activity measures to guide treatment decisions. However, evidence on the effect of these data on long-term outcome is scarce. The search data informed the expert committee regarding the formulation of recommendations and a research agenda. PMID:23740234

  10. Soot on snow in Iceland: First results on black carbon and organic carbon in Iceland 2016 snow and ice samples, including the glacier Solheimajökull

    Science.gov (United States)

    Meinander, Outi; Dagsson-Waldhauserova, Pavla; Gritsevich, Maria; Aurela, Minna; Arnalds, Olafur; Dragosics, Monika; Virkkula, Aki; Svensson, Jonas; Peltoniemi, Jouni; Kontu, Anna; Kivekäs, Niku; Leppäranta, Matti; de Leeuw, Gerrit; Laaksonen, Ari; Lihavainen, Heikki; Arslan, Ali N.; Paatero, Jussi

    2017-04-01

    New results on black carbon (BC) and organic carbon (OC) on snow and ice in Iceland in 2016 will be presented in connection to our earlier results on BC and OC on Arctic seasonal snow surface, and in connection to our 2013 and 2016 experiments on effects of light absorbing impurities, including Icelandic dust, on snow albedo, melt and density. Our sampling included the glacier Solheimajökull in Iceland. The mass balance of this glacier is negative and it has been shrinking during the last 20 years by 900 meters from its southwestern corner. Icelandic snow and ice samples were not expected to contain high concentrations of BC, as power generation with domestic renewable water and geothermal power energy sources cover 80 % of the total energy consumption in Iceland. Our BC results on filters analyzed with a Thermal/Optical Carbon Aerosol Analyzer (OC/EC) confirm this assumption. Other potential soot sources in Iceland include agricultural burning, industry (aluminum and ferroalloy production and fishing industry), open burning, residential heating and transport (shipping, road traffic, aviation). On the contrary to low BC, we have found high concentrations of organic carbon in our Iceland 2016 samples. Some of the possible reasons for those will be discussed in this presentation. Earlier, we have measured and reported unexpectedly low snow albedo values of Arctic seasonally melting snow in Sodankylä, north of Arctic Circle. Our low albedo results of melting snow have been confirmed by three independent data sets. We have explained these low values to be due to: (i) large snow grain sizes up to 3 mm in diameter (seasonally melting snow); (ii) meltwater surrounding the grains and increasing the effective grain size; (iii) absorption caused by impurities in the snow, with concentration of elemental carbon (black carbon) in snow of 87 ppb, and organic carbon 2894 ppb. The high concentrations of carbon were due to air masses originating from the Kola Peninsula, Russia

  11. Effect of current mode on PEO treatment of magnesium in Ca- and P-containing electrolyte and resulting coatings

    Energy Technology Data Exchange (ETDEWEB)

    Gao, Yonghao [Department of Materials Science and Engineering, University of Sheffield, Mappin Street, Sheffield S1 3JD (United Kingdom); Yerokhin, Aleksey, E-mail: a.yerokhin@sheffield.ac.uk [Department of Materials Science and Engineering, University of Sheffield, Mappin Street, Sheffield S1 3JD (United Kingdom); National University of Science and Technology “MISIS”, Leninsky Prospect, 4, Moscow 119049 (Russian Federation); Matthews, Allan [Department of Materials Science and Engineering, University of Sheffield, Mappin Street, Sheffield S1 3JD (United Kingdom)

    2014-10-15

    Highlights: • MgO-Na{sub 4}Ca(PO{sub 3}){sub 6} coatings produced on cp-Mg in both PUP- and PBP-PEO modes. • Negative biasing affects PEO processing of cp-Mg in Ca(OH){sub 2}-Na{sub 3}PO{sub 4} electrolyte. • Thicker and macro defect-free PUP-PEO coatings provide better corrosion protection. • Corrosion mechanisms of PEO-treated cp-Mg in SBF discussed. - Abstract: Plasma electrolytic oxidation (PEO) coatings were produced on commercially pure magnesium in a biologically friendly electrolyte composed of 2 g L{sup −1} Ca(OH){sub 2} and 12 g L{sup −1} Na{sub 3}PO{sub 4}·12H{sub 2}O using pulsed unipolar and bipolar current regimes with negative biasing varying from 0 to 20 mA cm{sup −2}. Analysis of voltage transients was performed to characterise the PEO processes. The coating morphology and phase composition were studied by scanning electron microscopy and X-ray diffraction technique, respectively. In vitro corrosion performance of the coatings was evaluated in a simulated body fluid at 37 ± 1 °C, using electrochemical techniques including open circuit potential monitoring, electrochemical impedance spectroscopy and potentiodynamic polarisation scans. The influence of the negative biasing on the PEO process and resulting coating characteristics is discussed. Unlike generally recognised beneficial effects of the negative biasing in PEO treatments of some other metal-electrolyte systems, it was found that detrimental effects are induced to the coatings on cp-Mg produced in the studied electrolyte when the negative current amplitude increases, which may be attributed to hydrogen liberation at the coating/substrate interface during the negative biasing cycles. As a result, a deterioration of vitro corrosion performance was observed for the pulsed bipolar PEO coatings compared to those produced using the pulsed unipolar regime which provides better quality coatings.

  12. The association of the Clock 3111 T/C SNP with lipids and lipoproteins including small dense low-density lipoprotein: results from the Mima study

    Directory of Open Access Journals (Sweden)

    Takahashi Kaoru

    2010-10-01

    Full Text Available Abstract Background The clock molecule plays major roles in circadian rhythmicity and regulating lipid and glucose metabolism in peripheral organs. Disruption of the circadian rhythm can lead to cardiometabolic disorders. The existence of small dense low-density lipoprotein (sdLDL in the circulation, an abnormality of lipid metabolism, in part associated with lifestyle, is also one of risk parameters for cardiometabolic disorders. The 3111 T/C single nucleotide polymorphism (SNP of the Clock gene has been reported to be associated with lifestyle including morning/evening preference. We investigated whether the Clock 3111 T/C SNP may affect lipids and lipoproteins including sdLDL. Methods In 365 community-dwelling subjects (170 men and 195 women, mean age 63 ± 14 years, the 3111 T/C SNP was genotyped using a fluorescent allele-specific DNA primer assay system. The levels of sdLDL were measured with the electrophoretic separation of lipoproteins employing the Lipoprint system. Results The frequency of the Clock 3111 C allele was 0.14. The area of sdLDL did not differ between the subjects with obesity and those without. In carriers of T/T homozygotes, the area of sdLDL was significantly higher compared with carriers of the C allele (T/C or C/C (1.7 ± 3.4 vs. 0.8 ± 1.9%; p Clock 3111 T/C SNP (β = -0.114, p Conclusion Our findings indicated that the Clock 3111 T/C SNP might be associated with the existence of sdLDL.

  13. Pharmaceutical Market Access: current state of affairs and key challenges – results of the Market Access Launch Excellence Inventory (MALEI

    Directory of Open Access Journals (Sweden)

    Marcus A. Koch

    2015-12-01

    Full Text Available Objectives: To take inventory of the current state of affairs of Market Access Launch Excellence in the life sciences industry. To identify key gaps and challenges for Market Access (MA and discuss how they can be addressed. To generate a baseline for benchmarking MA launch excellence. Methodology: An online survey was conducted with pharmaceutical executives primarily working in MA, marketing, or general management. The survey aimed to evaluate MA excellence prerequisites across the product life cycle (rated by importance and level of implementation and to describe MA activity models in the respective companies. Composite scores were calculated from respondents’ ratings and answers. Results: Implementation levels of MA excellence prerequisites generally lagged behind their perceived importance. Item importance and the respective level of implementation correlated well, which can be interpreted as proof of the validity of the questionnaire. The following areas were shown to be particularly underimplemented: 1 early integration of MA and health economic considerations in research and development decision making, 2 developing true partnerships with payers, including the development of services ‘beyond the pill’, and 3 consideration of human resource and talent management. The concept of importance-adjusted implementation levels as a hybrid parameter was introduced and shown to be a viable tool for benchmarking purposes. More than 70% of respondents indicated that their companies will invest broadly in MA in terms of capital and headcount within the next 3 years. Conclusions: MA (launch excellence needs to be further developed in order to close implementation gaps across the entire product life cycle. As MA is a comparatively young pharmaceutical discipline in a complex and dynamic environment, this effort will require strategic focus and dedication. The Market Access Launch Excellence Inventory benchmarking tool may help guide decision

  14. Evaluation of false-positive results on Tc myocardial scintigraphy in patients with coronary artery bypass grafting including left internal thoracic artery-left anterior descending artery grafting

    Energy Technology Data Exchange (ETDEWEB)

    Hashimoto, Koichi; Shibata, Takahiro [Jikei Univ., Tokyo (Japan). School of Medicine; Imai, Kamon

    2000-11-01

    Stress myocardial scintigraphy in patients who have undergone coronary artery bypass grafting (CABG) frequently shows false-positive results. To investigate the reason for these false-positive results, two different stress tests-adenosine triphosphate (ATP) stress testing and ergometer exercise testing, and Tc-tetrofosmin myocardial scintigraphy were performed with a 1-day stress/rest protocol. The subjects were 6 patients with a history of myocardial infarction (MI) and 14 patients with a history of angina pectoris (AP) who had undergone CABG that included left internal thoracic artery-left anterior descending artery grafting. Graft patency was confirmed with coronary angiography. Short-axis images were reconstructed with single photon emission tomography. The severity of perfusion defects on short-axis images was evaluated quantitatively with a normal database as severity score, and the difference in severity score between stress and rest was defined as fill-in. Fill-in on the ATP stress test was 3.1{+-}7.0 in the AP group and 16.3{+-}13.2 in the MI group (p<0.01). Fill-in on the exercise stress test was 2.7{+-}8.3 in the AP group and 34.8{+-}20.6 in the MI group (p<0.01). In the MI group, fill-in on the exercise stress test was significantly greater than that on the ATP stress test (p<0.05). The exercise time and the amount of exercise stress in patients with MI were significantly greater than those in patients with AP. In conclusion, coronary flow reserve may play a role in false positive-finding on myocardial perfusion scintigraphy in patients who have undergone CABG. (author)

  15. Influence of the Dermis Thickness on the Results of the Skin Treatment with Monopolar and Bipolar Radiofrequency Currents

    Directory of Open Access Journals (Sweden)

    Ilja L. Kruglikov

    2016-01-01

    Full Text Available Electrically layered tissue structure significantly modifies distribution of radiofrequency (RF current in the dermis and in the subcutaneous adipose tissue comparing to that in a homogeneous medium. On the basis of the simple model of RF current distribution in a two-layer skin containing dermis and subcutis, we assess the influence of the dermal thickness on the current density in different skin layers. Under other equal conditions, current density in the dermis is higher for the skin having thinner dermis. This contradicts the main paradigm of the RF theory stating that treatment results are mainly dependent on the maximal temperature reached in a target tissue, since the best short- and long-term clinical results of RF application to the skin were reported in the areas having thicker dermis. To resolve this contradiction, it is proposed that the long-term effect of RF can be realized through a structural modification of the subcutaneous fat depot adjacent to the treated skin area. Stimulation of these cells located near the interface dermis/subcutis will demand the concentration of applied RF energy in this area and will require the optimal arrangement of RF electrodes on the skin surface.

  16. Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: results of genome-wide association analyses including 4659 European individuals

    Science.gov (United States)

    Heid, Iris M.; Henneman, Peter; Hicks, Andrew; Coassin, Stefan; Winkler, Thomas; Aulchenko, Yurii S.; Fuchsberger, Christian; Song, Kijoung; Hivert, Marie-France; Waterworth, Dawn M.; Timpson, Nicholas J.; Richards, J. Brent; Perry, John R.B.; Tanaka, Toshiko; Amin, Najaf; Kollerits, Barbara; Pichler, Irene; Oostra, Ben A.; Thorand, Barbara; Frants, Rune R.; Illig, Thomas; Dupuis, Josée; Glaser, Beate; Spector, Tim; Guralnik, Jack; Egan, Josephine M.; Florez, Jose C.; Evans, David M.; Soranzo, Nicole; Bandinelli, Stefania; Carlson, Olga D.; Frayling, Timothy M.; Burling, Keith; Smith, George Davey; Mooser, Vincent; Ferrucci, Luigi; Meigs, James B.; Vollenweider, Peter; van Dijk, Ko Willems; Pramstaller, Peter; Kronenberg, Florian; van Duijn, Cornelia M.

    2009-01-01

    Objective Plasma adiponectin is strongly associated with various components of metabolic syndrome, type 2 diabetes and cardiovascular outcomes. Concentrations are highly heritable and differ between men and women. We therefore aimed to investigate the genetics of plasma adiponectin in men and women. Methods We combined genome-wide association scans of three population-based studies including 4659 persons. For the replication stage in 13795 subjects, we selected the 20 top signals of the combined analysis, as well as the 10 top signals with p-values less than 1.0*10-4 for each the men- and the women-specific analyses. We further selected 73 SNPs that were consistently associated with metabolic syndrome parameters in previous genome-wide association studies to check for their association with plasma adiponectin. Results The ADIPOQ locus showed genome-wide significant p-values in the combined (p=4.3*10-24) as well as in both women- and men-specific analyses (p=8.7*10-17 and p=2.5*10-11, respectively). None of the other 39 top signal SNPs showed evidence for association in the replication analysis. None of 73 SNPs from metabolic syndrome loci exhibited association with plasma adiponectin (p>0.01). Conclusions We demonstrated the ADIPOQ gene as the only major gene for plasma adiponectin, which explains 6.7% of the phenotypic variance. We further found that neither this gene nor any of the metabolic syndrome loci explained the sex differences observed for plasma adiponectin. Larger studies are needed to identify more moderate genetic determinants of plasma adiponectin. PMID:20018283

  17. Randomized comparison of renal denervation versus intensified pharmacotherapy including spironolactone in true-resistant hypertension: six-month results from the Prague-15 study.

    Science.gov (United States)

    Rosa, Ján; Widimský, Petr; Toušek, Petr; Petrák, Ondřej; Čurila, Karol; Waldauf, Petr; Bednář, František; Zelinka, Tomáš; Holaj, Robert; Štrauch, Branislav; Šomlóová, Zuzana; Táborský, Miloš; Václavík, Jan; Kociánová, Eva; Branny, Marian; Nykl, Igor; Jiravský, Otakar; Widimský, Jiří

    2015-02-01

    This prospective, randomized, open-label multicenter trial evaluated the efficacy of catheter-based renal denervation (Symplicity, Medtronic) versus intensified pharmacological treatment including spironolactone (if tolerated) in patients with true-resistant hypertension. This was confirmed by 24-hour ambulatory blood pressure monitoring after excluding secondary hypertension and confirmation of adherence to therapy by measurement of plasma antihypertensive drug levels before enrollment. One-hundred six patients were randomized to renal denervation (n=52), or intensified pharmacological treatment (n=54) with baseline systolic blood pressure of 159±17 and 155±17 mm Hg and average number of drugs 5.1 and 5.4, respectively. A significant reduction in 24-hour average systolic blood pressure after 6 months (-8.6 [95% cofidence interval: -11.8, -5.3] mm Hg; P<0.001 in renal denervation versus -8.1 [95% cofidence interval: -12.7, -3.4] mm Hg; P=0.001 in pharmacological group) was observed, which was comparable in both groups. Similarly, a significant reduction in systolic office blood pressure (-12.4 [95% cofidence interval: -17.0, -7.8] mm Hg; P<0.001 in renal denervation versus -14.3 [95% cofidence interval: -19.7, -8.9] mm Hg; P<0.001 in pharmacological group) was present. Between-group differences in change were not significant. The average number of antihypertensive drugs used after 6 months was significantly higher in the pharmacological group (+0.3 drugs; P<0.001). A significant increase in serum creatinine and a parallel decrease of creatinine clearance were observed in the pharmacological group; between-group difference were borderline significant. The 6-month results of this study confirmed the safety of renal denervation. In conclusion, renal denervation achieved reduction of blood pressure comparable with intensified pharmacotherapy.

  18. Results of chemical analysis from the 2008-2009 National Rivers and Streams Assessment Survey, including persistent organic pollutants and pharmaceuticals

    Data.gov (United States)

    U.S. Environmental Protection Agency — In 2008-2009, fish are were collected from approximately 560 national streams, which included a representative subset of 154 urban river sites, which were in close...

  19. HMSRP Hawaiian Monk Seal Specimen Data (includes physical specimens, collection information, status, storage locations, and laboratory results associated with individual specimens)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set includes physical specimens, paper logs and Freezerworks database of all logged information on specimens collected from Hawaiian monk seals since 1975....

  20. The alkaline single cell electrophoresis assay with eight mouse organs: results with 22 mono-functional alkylating agents (including 9 dialkyl N-nitrosoamines) and 10 DNA crosslinkers.

    Science.gov (United States)

    Tsuda, S; Matsusaka, N; Madarame, H; Miyamae, Y; Ishida, K; Satoh, M; Sekihashi, K; Sasaki, Y F

    2000-04-13

    The genotoxicity of 22 mono-functional alkylating agents (including 9 dialkyl N-nitrosoamines) and 10 DNA crosslinkers selected from IARC (International Agency for Research on Cancer) groups 1, 2A, and 2B was evaluated in eight mouse organs with the alkaline single cell gel electrophoresis (SCGE) (comet) assay. Groups of four mice were treated once intraperitoneally at the dose at which micronucleus tests had been conducted, and the stomach, colon, liver, kidney, bladder, lung, brain, and bone marrow were sampled 3, 8, and/or 24 h later. All chemicals were positive in the SCGE assay in at least one organ. Of the 22 mono-functional alkylating agents, over 50% were positive in all organs except the brain and bone marrow. The two subsets of mono-functional alkylating agents differed in their bone marrow genotoxicity: only 1 of the 9 dialkyl N-nitrosoamines was positive in bone marrow as opposed to 8 of the 13 other alkylating agents, reflecting the fact that dialkyl N-nitrosoamines are poor micronucleus inducers in hematopoietic cells. The two groups of mono-functional alkylating agents also differ in hepatic carcinogenicity in spite of the fact that they are similar in hepatic genotoxicity. While dialkyl N-nitrosoamines produce tumors primarily in mouse liver, only one (styrene-7,8-oxide) out of 10 of the other type of mono-functional alkylating agents is a mouse hepatic carcinogen. Taking into consideration our previous results showing high concordance between hepatic genotoxicity and carcinogenicity for aromatic amines and azo compounds, a possible explanation for the discrepancy might be that chemicals that require metabolic activation show high concordance between genotoxicity and carcinogenicity in the liver. A high percent of the 10 DNA crosslinkers were positive in the SCGE assay in the gastrointestinal mucosa, but less than 50% were positive in the liver and lung. In this study, we allowed 10 min alkali-unwinding to obtain low and stable control values

  1. Late sodium current block for drug-induced long QT syndrome: Results from a prospective clinical trial.

    Science.gov (United States)

    Johannesen, L; Vicente, J; Mason, J W; Erato, C; Sanabria, C; Waite-Labott, K; Hong, M; Lin, J; Guo, P; Mutlib, A; Wang, J; Crumb, W J; Blinova, K; Chan, D; Stohlman, J; Florian, J; Ugander, M; Stockbridge, N; Strauss, D G

    2016-02-01

    Drug-induced long QT syndrome has resulted in many drugs being withdrawn from the market. At the same time, the current regulatory paradigm for screening new drugs causing long QT syndrome is preventing drugs from reaching the market, sometimes inappropriately. In this study, we report the results of a first-of-a-kind clinical trial studying late sodium (mexiletine and lidocaine) and calcium (diltiazem) current blocking drugs to counteract the effects of hERG potassium channel blocking drugs (dofetilide and moxifloxacin). We demonstrate that both mexiletine and lidocaine substantially reduce heart-rate corrected QT (QTc) prolongation from dofetilide by 20 ms. Furthermore, all QTc shortening occurs in the heart-rate corrected J-Tpeak (J-Tpeak c) interval, the biomarker we identified as a sign of late sodium current block. This clinical trial demonstrates that late sodium blocking drugs can substantially reduce QTc prolongation from hERG potassium channel block and assessment of J-Tpeak c may add value beyond only assessing QTc.

  2. Prenatal recruitment of participants for a birth cohort study including cord blood collection: results of a feasibility study in Bremen, Germany

    Directory of Open Access Journals (Sweden)

    Ernst, Sinja Alexandra

    2015-04-01

    their primary care gynecologist or later on in hospital by the attending obstetricians or project staff.Results: Of the 22 invited primary care gynecologists requested to enroll pregnant women for the study, 8 gynecologists actually collaborated. A total of 200 eligible women were invited to participate in the study, 48 (24% of whom agreed. 34 women were enrolled by primary care gynecologists, with one gynecologist enrolling 26 women. Twelve of recruited via hospitals were enrolled by study staff. A total of 41 women consented to the collection of umbilical cord blood and maternal blood samples, and samples could be stored for 54% of them. Reason for non-participation were the uncertainty whether or not the full study would be conducted and the fact that the participants were not willing to decide for their children whether or not genetic information (cord blood can be stored for research purposes.Conclusion: Enrolling parents in a birth cohort study that includes biosampling is a challenge, but participation can be improved through close collaboration with primary care gynecologists and maternity hospitals. Cord blood collection may impede participation, especially when maternity hospitals offer an alternative option for cord blood donation.

  3. Labeling programs and efficiency standards to control the energy consumption of household appliances: current situation, main results and recommendations

    Energy Technology Data Exchange (ETDEWEB)

    Menanteau, Ph.

    2000-09-01

    To control the rise in electricity consumption for specific uses, the industrialized countries started by introducing special programs aimed at improving energy efficiency. Among the different instruments available, labeling programs and minimum energy performance standards (MEPS) have proved to be very effective. The first part of this document presents the current situation, the main results and recommendations concerning the labeling programs and efficiency standards to control the energy consumption of household appliances. This analyze is done for each country in details providing the name of the program or measure, the date of implementation, the objective and the main characteristics of the program, the impacts and evaluation. (A.L.B.)

  4. Brine migration resulting from CO2 injection into saline aquifers – An approach to risk estimation including various levels of uncertainty

    DEFF Research Database (Denmark)

    Walter, Lena; Binning, Philip John; Oladyshkin, Sergey

    2012-01-01

    for large-scale 3D models including complex physics. Therefore, we apply a model reduction based on arbitrary polynomial chaos expansion combined with probabilistic collocation method. It is shown that, dependent on data availability, both types of uncertainty can be equally significant. The presented study...... features such as caprock properties, faults, and distinct geological layers. This is considered in this work by 6 different scenarios having different characteristic geological features. On the other hand, Monte Carlo methods are a classical approach to address statistical uncertainty. This is not feasible...

  5. Self-Consistent Model of Magnetospheric Electric Field, Ring Current, Plasmasphere, and Electromagnetic Ion Cyclotron Waves: Initial Results

    Science.gov (United States)

    Gamayunov, K. V.; Khazanov, G. V.; Liemohn, M. W.; Fok, M.-C.; Ridley, A. J.

    2009-01-01

    Further development of our self-consistent model of interacting ring current (RC) ions and electromagnetic ion cyclotron (EMIC) waves is presented. This model incorporates large scale magnetosphere-ionosphere coupling and treats self-consistently not only EMIC waves and RC ions, but also the magnetospheric electric field, RC, and plasmasphere. Initial simulations indicate that the region beyond geostationary orbit should be included in the simulation of the magnetosphere-ionosphere coupling. Additionally, a self-consistent description, based on first principles, of the ionospheric conductance is required. These initial simulations further show that in order to model the EMIC wave distribution and wave spectral properties accurately, the plasmasphere should also be simulated self-consistently, since its fine structure requires as much care as that of the RC. Finally, an effect of the finite time needed to reestablish a new potential pattern throughout the ionosphere and to communicate between the ionosphere and the equatorial magnetosphere cannot be ignored.

  6. Efficacy and safety of deferasirox compared with deferoxamine in sickle cell disease: two-year results including pharmacokinetics and concomitant hydroxyurea.

    Science.gov (United States)

    Vichinsky, Elliott; Torres, Marcela; Minniti, Caterina P; Barrette, Stephane; Habr, Dany; Zhang, Yiyun; Files, Beatrice

    2013-12-01

    We report a prospective, randomized, Phase II study of deferasirox and deferoxamine (DFO) in sickle cell disease patients with transfusional iron overload, with all patients continuing on deferasirox after 24 weeks, for up to 2 years. The primary objective was to evaluate deferasirox safety compared with DFO; long-term efficacy and safety of deferasirox was also assessed. We also report, for the first time, the safety and pharmacokinetics of deferasirox in patients concomitantly receiving hydroxyurea. Deferasirox (n = 135) and DFO (n = 68) had comparable safety profiles over 24 weeks. Adverse events (AEs) secondary to drug administration were reported in 26.7% of patients in the deferasirox cohort and 28.6% in the DFO cohort. Gastrointestinal disorders were more common with deferasirox, including diarrhea (10.4% versus 3.6%) and nausea (5.2% versus 3.6%). The most common AE in the DFO group was injection-site pain irritation, which occurred in 7% of patients. Acute renal failure occurred in one patient on deferasirox who was continued on medication despite progressive impairment of renal function parameters. Serum ferritin levels were reduced in both treatment groups. Patients continuing on deferasirox for up to 2 years demonstrated an absolute median serum ferritin decrease of -614 ng/mL (n = 96). Increasing deferasirox dose was associated with improved response and a continued manageable safety profile. Concomitant hydroxyurea administration (n = 28) did not appear to influence the efficacy, safety (including liver and kidney function), and pharmacokinetic parameters of deferasirox.

  7. The association of the Clock 3111 T/C SNP with lipids and lipoproteins including small dense low-density lipoprotein: results from the Mima study.

    Science.gov (United States)

    Tsuzaki, Kokoro; Kotani, Kazuhiko; Sano, Yoshiko; Fujiwara, Shinji; Takahashi, Kaoru; Sakane, Naoki

    2010-10-21

    The clock molecule plays major roles in circadian rhythmicity and regulating lipid and glucose metabolism in peripheral organs. Disruption of the circadian rhythm can lead to cardiometabolic disorders. The existence of small dense low-density lipoprotein (sdLDL) in the circulation, an abnormality of lipid metabolism, in part associated with lifestyle, is also one of risk parameters for cardiometabolic disorders. The 3111 T/C single nucleotide polymorphism (SNP) of the Clock gene has been reported to be associated with lifestyle including morning/evening preference. We investigated whether the Clock 3111 T/C SNP may affect lipids and lipoproteins including sdLDL. In 365 community-dwelling subjects (170 men and 195 women, mean age 63 ± 14 years), the 3111 T/C SNP was genotyped using a fluorescent allele-specific DNA primer assay system. The levels of sdLDL were measured with the electrophoretic separation of lipoproteins employing the Lipoprint system. The frequency of the Clock 3111 C allele was 0.14. The area of sdLDL did not differ between the subjects with obesity and those without. In carriers of T/T homozygotes, the area of sdLDL was significantly higher compared with carriers of the C allele (T/C or C/C) (1.7 ± 3.4 vs. 0.8 ± 1.9%; p < 0.05). A multiple regression analysis showed that the area of sdLDL was significantly and negatively correlated with the Clock 3111 T/C SNP (β = -0.114, p < 0.05), independently of age, sex, body mass index, and exercise habits. Our findings indicated that the Clock 3111 T/C SNP might be associated with the existence of sdLDL.

  8. Outcome of Triple Antiplatelet Therapy Including Cilostazol in Elderly Patients with ST-Elevation Myocardial Infarction who Underwent Primary Percutaneous Coronary Intervention: Results from the INTERSTELLAR Registry.

    Science.gov (United States)

    Jang, Ho-Jun; Park, Sang-Don; Park, Hyun Woo; Suh, Jon; Oh, Pyung Chun; Moon, Jeonggeun; Lee, Kyounghoon; Kang, Woong Chol; Kwon, Sung Woo; Kim, Tae-Hoon

    2017-06-01

    Compared with dual antiplatelet therapy including aspirin and clopidogrel, triple antiplatelet therapy including cilostazol has a mortality benefit in patients with ST-segment elevation myocardial infarction. However, whether the mortality benefit persists in elderly patients is not clear. From 2007 to 2014, 1278 patients with ST-segment elevation myocardial infarction who underwent primary percutaneous coronary intervention were retrospectively analyzed. The patients were divided into four groups by age (antiplatelet strategy (triple or dual antiplatelet therapy). We compared the mortality rates between the triple and dual antiplatelet therapy groups. There were 1052 (male, 85%; mean age, 56.3 ± 10.4 years) patients in the young group and 241 (male, 52.7%; mean age, 80.3 ± 4.5 years) patients in the elderly group. In the young and elderly groups, 220 (20.9%) and 28 (12.3%) patients were treated with triple antiplatelet therapy. During a 1-year follow-up period, 80 patients died (4.2% in the young group vs. 15.5% in the elderly group). Kaplan-Meier survival analysis revealed that triple antiplatelet therapy was associated with a lower mortality rate in the young group (log-rank, p = 0.005). Although there were more angiographic high-risk patients in the elderly group, similar mortality rates were reported (log-rank, p = 0.803) without increased bleeding rates (1 vs. 3.6% in the elderly group, p = 0.217). Triple antiplatelet therapy might be a better antiplatelet regimen than dual antiplatelet therapy for patients with ST-segment elevation myocardial infarction. Although this benefit was strong in patients aged <75 years, no definite increase in major bleeding was seen for elderly patients (aged ≥75 years).

  9. GAMMA RADIATION INTERACTS WITH MELANIN TO ALTER ITS OXIDATION-REDUCTION POTENTIAL AND RESULTS IN ELECTRIC CURRENT PRODUCTION

    Energy Technology Data Exchange (ETDEWEB)

    Turick, C.; Ekechukwu, A.; Milliken, C.

    2011-05-17

    The presence of melanin pigments in organisms is implicated in radioprotection and in some cases, enhanced growth in the presence of high levels of ionizing radiation. An understanding of this phenomenon will be useful in the design of radioprotective materials. However, the protective mechanism of microbial melanin in ionizing radiation fields has not yet been elucidated. Here we demonstrate through the electrochemical techniques of chronoamperometry, chronopotentiometry and cyclic voltammetry that microbial melanin is continuously oxidized in the presence of gamma radiation. Our findings establish that ionizing radiation interacts with melanin to alter its oxidation-reduction potential. Sustained oxidation resulted in electric current production and was most pronounced in the presence of a reductant, which extended the redox cycling capacity of melanin. This work is the first to establish that gamma radiation alters the oxidation-reduction behavior of melanin, resulting in electric current production. The significance of the work is that it provides the first step in understanding the initial interactions between melanin and ionizing radiation taking place and offers some insight for production of biomimetic radioprotective materials.

  10. Essential and toxic element concentrations in blood and urine and their associations with diet: Results from a Norwegian population study including high-consumers of seafood and game

    Energy Technology Data Exchange (ETDEWEB)

    Birgisdottir, B.E.; Knutsen, H.K.; Haugen, M.; Gjelstad, I.M. [Division of Environmental Medicine, Norwegian Institute of Public Health, Oslo (Norway); Jenssen, M.T.S. [Norwegian Institute for Water Research, Oslo (Norway); Ellingsen, D.G.; Thomassen, Y. [National Institute of Occupational Health, Oslo (Norway); Alexander, J. [Office of the Director-General, Norwegian Institute of Public Health, Oslo (Norway); Meltzer, H.M. [Division of Environmental Medicine, Norwegian Institute of Public Health, Oslo (Norway); Brantsæter, A.L., E-mail: Anne.Lise.Brantsaeter@fhi.no [Division of Environmental Medicine, Norwegian Institute of Public Health, Oslo (Norway)

    2013-10-01

    elements • The elements are selenium, iodine, arsenic, mercury, cadmium and lead. • Exposures did not give rise to nutritional or toxicological concerns. • A distinct pattern of associated biological markers was found including four elements. • The pattern, including iodine, selenium, arsenic and mercury reflected seafood intake.

  11. The impact of including husbands in antenatal health education services on maternal health practices in urban Nepal: results from a randomized controlled trial.

    Science.gov (United States)

    Mullany, Britta C; Becker, S; Hindin, M J

    2007-04-01

    Observational studies suggest that including men in reproductive health interventions can enhance positive health outcomes. A randomized controlled trial was designed to test the impact of involving male partners in antenatal health education on maternal health care utilization and birth preparedness in urban Nepal. In total, 442 women seeking antenatal services during second trimester of pregnancy were randomized into three groups: women who received education with their husbands, women who received education alone and women who received no education. The education intervention consisted of two 35-min health education sessions. Women were followed until after delivery. Women who received education with husbands were more likely to attend a post-partum visit than women who received education alone [RR = 1.25, 95% CI = (1.01, 1.54)] or no education [RR = 1.29, 95% CI = (1.04, 1.60)]. Women who received education with their husbands were also nearly twice as likely as control group women to report making >3 birth preparations [RR = 1.99, 95% CI = (1.10, 3.59)]. Study groups were similar with respect to attending the recommended number of antenatal care checkups, delivering in a health institution or having a skilled provider at birth. These data provide evidence that educating pregnant women and their male partners yields a greater net impact on maternal health behaviors compared with educating women alone.

  12. First results of Indian - Current meter moorings along The equator: Vertical current structure variability at equator, 93 degrees E during February-December, 2000

    Digital Repository Service at National Institute of Oceanography (India)

    Murty, V.S.N.; Suryanarayana, A.; Sarma, M.S.S.; Tilvi, V.; Fernando, V.; Nampoothiri, G.; Sardar, A.; Gracias, D.; Khalap, S.

    are weak while the low pass filtered (49-hour) current data show considerable meso-scale variability, comprising of Intraseasonal Oscillations (ISO) of period 10-20 day and 40.5 day. The 10-20 day ISO is associated with similar variability in surface wind...

  13. Notes on the mosquitoes of Nepal. IV. Results of the 1994 collecting in the Midwestern Region, including new country records and voucher confirmation (Diptera, Culicidae).

    Science.gov (United States)

    Darsie, R F; Courtney, G W; Pradhan, S P

    1996-03-01

    During 1994, field studies were conducted in the Midwestern Region of Nepal. Two camps were located in the "inner terai," low mountain valleys between the Churia Range and the Mahabarat Lekh. A third camp was in the mountains at Jumla. Visits were made to 2 high mountain sites, Simikot, Humla District, and Rara National Park. The result from all these sampling sites was the recovery of 6 new country records, 5 in the genus Aedes and 1 in the genus Heizmannia. Some mosquitoes in the Nepal checklist had no voucher specimens. Locality data are given for 9 of these. Biodata on another species that is quite rare in Nepal are given.

  14. Statement on the exposure assessment of sodium stearoyl-2-lactylate and calcium stearoyl-2-lactylate including exposure resulting from extension of the authorisation of sodium stearoyl-2-lactylates

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS

    2013-03-01

    Full Text Available Following a request by the European Commission, the Scientific Panel on Food Additives and Nutrient Sources added to Food (ANS carried out an exposure assessment of sodium stearoyl-2-lactylate (E 481 and calcium stearoyl-2-lactylate (E 482 as a food additive, including an extension of the uses to use the additives in emulsified cooked meat products (e.g. mortadella, paté. Reflecting the data on actual use levels provided by food industry, the combined exposure to sodium stearoyl-2-lactylate and calcium stearoyl-2-lactylate is in the range 6-55 mg/kg bw/day for toddlers, 14-54 mg/kg bw/day for children, 13-27 mg/kg bw/day for adolescents, 4-16 mg/kg bw/day for adults, and 3-13 mg/kg bw/day for the elderly at the mean level. For exposure at high levels, ranges of 22-109 mg/kg bw/day for toddlers, 28-107 mg/kg bw/day for children, 21-46 mg/kg bw/day for adolescents, 15-33 mg/kg bw/day for adults, and 9-30 mg/kg bw/day were calculated for the elderly. The extension of the authorisation for the use of sodium stearoyl-2-lactylate in emulsified cooked meat products (e.g. mortadella, paté would not lead to an increase of exposure based on the approach taken for the exposure assessment for the two food additives.

  15. The current status of interventional radiology in Canada: results of a survey by the Canadian Interventional Radiology Association

    Energy Technology Data Exchange (ETDEWEB)

    Millward, S.F.; Holley, M.L. [Univ. of Western Ontario, London Health Sciences Centre, Dept. of Radiology, London, Ontario (Canada)

    2001-04-01

    To evaluate the current status of interventional radiology in Canada. A questionnaire was sent to 28 Canadian interventional radiologists (defined as a physician who performs any type of interventional procedure, including biopsies, but excluding interventional neuroradiology) practising in both tertiary and community hospitals in the major centres in all provinces except Prince Edward Island. Twenty-two (79%) of 28 surveys were completed and returned, providing data about 86 interventional radiologists (IRs). IRs were performing almost all of the following procedures at their institutions: inferior vena cava filter placement, venous angioplasty, dialysis fistula angioplasty, diagnostic and therapeutic pulmonary and bronchial artery procedures, diagnostic and therapeutic procedures of the lower extremity and renal arteries, percutaneous abscess and biliary drainage procedures, percutaneous nephrostomy, and fibroid embolization. A second group of procedures, performed by both IRs and non-radiologists in most institutions, included: all types of central venous catheter placements, pleural drainage, and gastrostomy tube placement. Procedures not being performed by anyone in a number of institutions included: dialysis graft thrombolysis, varicocele embolization, transjugular intrahepatic portosystemic shunts, palliative stenting of the gastrointestinal tract, fallopian tube recannalization, and liver and prostate tumour treatments. The factors most often limiting the respondents' ability to provide a comprehensive interventional service were the interventional radiology inventory budget and the availability of interventional radiology rooms; 50% of respondents indicated the number of available nurses, technologists and IRs was also an important limiting factor. IRs in Canada still play a major role in many of the most commonly performed procedures. However, limited availability of resources and personnel in many institutions may be hampering the ability of IRs to

  16. Practice of ultrasound-guided arthrocentesis and joint injection, including training and implementation, in Europe: results of a survey of experts and scientific societies

    DEFF Research Database (Denmark)

    Mandl, Peter; Naredo, Esperanza; Conaghan, Philip G

    2012-01-01

    Objectives. To document the practice and training opportunities of US-guided arthrocentesis and joint injection (UGAJ) among rheumatologists in the member countries of the European League Against Rheumatism (EULAR). Methods. An English-language questionnaire, containing questions on demographics......, clinical and practical aspects of UGAJ, training options in UGAJ for rheumatologists, UGAJ education in the rheumatology training curriculum and other structured education programmes in UGAJ was sent to three different groups: (i) all national rheumatology societies of EULAR; (ii) all national societies...... of the European Federation of Societies for Ultrasound in Medicine and Biology (EFSUMB); and (iii) 22 senior rheumatologists involved in EULAR musculoskeletal US training from 14 European countries, who were also asked to circulate the questionnaire among relevant colleagues. Results. Thirty-three (75%) of 44...

  17. Usability of a novel disposable autoinjector device for ixekizumab: results from a qualitative study and an open-label clinical trial, including patient-reported experience

    Science.gov (United States)

    Callis Duffin, Kristina; Bukhalo, Michael; Bobonich, Margaret A; Shrom, David; Zhao, Fangyi; Kershner, James R; Gill, Anne; Pangallo, Beth; Shuler, Catherine L; Bagel, Jerry

    2016-01-01

    Background Most biologic therapies for psoriasis are delivered via subcutaneous injection. Ixekizumab, an anti-interleukin 17A monoclonal antibody approved for patients with moderate-to-severe plaque psoriasis, is delivered subcutaneously via prefilled syringe or autoinjector. Here we report the results of an ixekizumab autoinjector usability study as well as the patient-reported experience with the autoinjector in a clinical trial. Methods The usability study enrolled 49 subjects (patients with a range of autoimmune conditions or their caregivers). Subjects were randomized to a trained or untrained group and were evaluated for their ability to perform an injection successfully when provided the device and the instructions for use. In the clinical trial, 102 subjects (patients with psoriasis or their caregivers) used the autoinjector to deliver injections of ixekizumab (80 mg every 2 weeks after a starting dose of 160 mg). At weeks 0, 4, and 8, subjects completed the subcutaneous administration assessment questionnaire, which assesses the ease of use and confidence with using an injection device. Results In the usability study, all subjects in the untrained arm performed successful injections, while two subjects in the trained arm had an injection failure. These incidences were not consistent with any pattern of issues with the device or the instructions for use. In the clinical trial, there were two injection failures of 674 total self-injections performed over 12 weeks. At the first use of the device, 95% of subjects either agreed or strongly agreed that the device was “overall easy to use”, and they felt “confident the dose was complete” according to the subcutaneous administration assessment questionnaire. Conclusion The ixekizumab autoinjector was used successfully by patients and caregivers with or without training. Subjects using the autoinjector in a clinical trial felt it was easy to use and felt confident while using it. PMID:27785115

  18. Usability of a novel disposable autoinjector device for ixekizumab: results from a qualitative study and an open-label clinical trial, including patient-reported experience

    Directory of Open Access Journals (Sweden)

    Callis Duffin K

    2016-10-01

    Full Text Available Kristina Callis Duffin,1 Michael Bukhalo,2 Margaret A Bobonich,3 David Shrom,4 Fangyi Zhao,4 James R Kershner,4 Anne Gill,4 Beth Pangallo,4 Catherine L Shuler,4 Jerry Bagel5 1Department of Dermatology, University of Utah School of Medicine, Salt Lake City, UT, 2Arlington Dermatology, Arlington Heights, IL, 3CWRU Schools of Medicine and Nursing, Case Western Reserve University Cleveland, OH, 4Lilly Research Labs, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN, 5Psoriasis Treatment Center of Central New Jersey, East Windsor, NJ, USA Background: Most biologic therapies for psoriasis are delivered via subcutaneous injection. Ixekizumab, an anti-interleukin 17A monoclonal antibody approved for patients with moderate-to-severe plaque psoriasis, is delivered subcutaneously via prefilled syringe or autoinjector. Here we report the results of an ixekizumab autoinjector usability study as well as the patient-reported experience with the autoinjector in a clinical trial. Methods: The usability study enrolled 49 subjects (patients with a range of autoimmune conditions or their caregivers. Subjects were randomized to a trained or untrained group and were evaluated for their ability to perform an injection successfully when provided the device and the instructions for use. In the clinical trial, 102 subjects (patients with psoriasis or their caregivers used the autoinjector to deliver injections of ixekizumab (80 mg every 2 weeks after a starting dose of 160 mg. At weeks 0, 4, and 8, subjects completed the subcutaneous administration assessment questionnaire, which assesses the ease of use and confidence with using an injection device. Results: In the usability study, all subjects in the untrained arm performed successful injections, while two subjects in the trained arm had an injection failure. These incidences were not consistent with any pattern of issues with the device or the instructions for use. In the clinical trial, there were two

  19. Guideline-recommended therapy, including beta-blocker utilization, in patients with chronic heart failure: results from a Canadian community hospital heart function clinic

    Directory of Open Access Journals (Sweden)

    Heffernan M

    2016-06-01

    Full Text Available Michael Heffernan Division of Cardiology, Oakville Trafalgar Memorial Hospital, Oakville, ON, Canada Abstract: A comprehensive analysis of beta-blocker utilization and other guideline-recommended therapies for the treatment of chronic heart failure in a Canadian community hospital heart function clinic has not been undertaken and was, therefore, the focus of this study. The proportion of patients who would be potential candidates for ivabridine and sacubitril–valsartan therapy as a result of fulfilling the criteria for enrollment in either the Systolic Heart failure treatment with the If inhibitor ivabradine Trial (SHIFT study (left-ventricular ejection fraction [LVEF] >35%, sinus rhythm, New York Heart Association II–IV or the Prospective Comparison of angiotensin receptor-neprilysin inhibitor (ARNI with angiotensin-converting enzyme inhibitor (ACEI to determine impact on global Mortality and Morbidity in Heart Failure (PARADIGM-HF study (LVEF <40%, New York Heart Association II–IV, glomerular filtration rate >30 mL/min, was also assessed. A retrospective cross-sectional analysis was carried out in all 371 patients treated in this community heart function clinic for at least a 12-month period. The patients were elderly (mean age 74±13.3 years and predominately male (61.5% with symptomatic (82.5% moderate left-ventricular dysfunction (LVEF 45.4%±15.6%. A substantial proportion of the patients also had a diagnosis of atrial fibrillation (52.8%. The total use of beta blockers exceeded 87%, while 100% of patients without a documented contraindication or intolerance to a beta blocker received therapy. Adherence to other guideline-recommended pharmacotherapies specifically for heart failure with reduced left ventricular ejection was high: 86.1% of the eligible patients were treated with an ACEI/angiotensin receptor blocker and 61.9% received a mineralcorticoid receptor antagonist. We determined that 13.7% of the complement of this heart

  20. Experimental Results of a DC Bus Voltage Level Control for a Load-Controlled Marine Current Energy Converter

    Directory of Open Access Journals (Sweden)

    Johan Forslund

    2015-05-01

    Full Text Available This paper investigates three load control methods for a  marine current energy converter using a vertical axis current  turbine (VACT mounted on a permanent magnet synchronous generator  (PMSG. The three cases are; a fixed AC load, a fixed pulse width  modulated (PWM DC load and DC bus voltage control of a DC  load. Experimental results show that the DC bus voltage control  reduces the variations of rotational speed by a factor of 3.5 at the cost  of slightly increased losses in the generator and transmission lines.  For all three cases, the tip speed ratio \\(\\lambda\\ can be kept close to  the expected \\(\\lambda_{opt}\\. The power coefficient is estimated to be  0.36 at \\(\\lambda_{opt}\\; however, for all three cases, the average  extracted power was about \\(\\sim 19\\\\%. A maximum power point  tracking (MPPT system, with or without water velocity measurement,  could increase the average extracted power.

  1. Determination of drugs in surface water and wastewater samples by liquid chromatography-mass spectrometry: Methods and preliminary results including toxicity studies with Vibrio fischeri

    Science.gov (United States)

    Farre, M.; Ferrer, I.; Ginebreda, A.; Figueras, M.; Olivella, L.; Tirapu, L.; Vilanova, M.; Barcelo, D.

    2001-01-01

    In the present work a combined analytical method involving toxicity and liquid chromatography-electrospray ionization-mass spectrometry (LC-ESI-MS) was developed for the determination of pharmaceutical compounds in water samples. The drugs investigated were the analgesics: ibuprofen, ketoprofen, naproxen, and diclofenac, the decomposition product of the acetyl salicylic acid: salicylic acid and one lipid lowering agent, gemfibrozil. The selected compounds are acidic substances, very polar and all of them are analgesic compounds that can be purchased without medical prescription. The developed protocol consisted, first of all, on the use Microtox?? and ToxAlert??100 toxicity tests with Vibrio fischeri for the different pharmaceutical drugs. The 50% effective concentration (EC50) values and the toxicity units (TU) were determined for every compound using both systems. Sample enrichment of water samples was achieved by solid-phase extraction procedure (SPE), using the Merck LiChrolut?? EN cartridges followed by LC-ESI-MS. Average recoveries loading 1 l of samples with pH=2 varied from 69 to 91% and the detection limits in the range of 15-56 ng/l. The developed method was applied to real samples from wastewater and surface-river waters of Catalonia (north-east of Spain). One batch of samples was analyzed in parallel also by High Resolution Gas Chromatography coupled with Mass Spectrometry (HRGC-MS) and the results have been compared with the LC-ESI-MS method developed in this work. ?? 2001 Elsevier Science B.V. All rights reserved.

  2. Long term efficacy and safety of Chinese made sirolimus eluting stents: results,including off label usage,from two centres over three years

    Institute of Scientific and Technical Information of China (English)

    ZHANG Qi; SHEN Wei-feng; GAO Run-lin; XU Bo; YANG Yue-jin; QIAO Shu-bin; ZHANG Rui-yan; ZHANG Jian-sheng; HU Jian; QIN Xue-wen; CHEN Ji-lin

    2008-01-01

    Background Multiple randomized clinical trials have demonstrated that drug eluting stents can significantly reduce the rates of restenosis and subsequent adverse events across lesion and patient.We investigated the medium term clinical efficacy and safety of Firebird sirolimus eluting stent (SES) in coronary artery disease.Methods The sample was 509 consecutive patients with coronary artery disease (CAD) who were treated by Firebird SES and finished three-year clinical follow-up.The occurrences of major adverse cardiac events (MACE) and Academic Research Consortium defined stent thrombosis (ST) were evaluated in patients with and without diabetes mellitus.Results Three hundred and thirty three patients (65.4%) were treated by Firebird SES by off label indications.Angiographic success was achieved in 98.3% of the lesions.MACE and target vessel revascularization rates at 6-month,1 year's and 3 years' clinical follow-up were 2.4% and 1.4%,4.1% and 2.8%,7.9% and 5.1%,respectively.The cumulative 3-year MACE free survival rate was 92.1%.After 3 years,DM patients had significantly higher rates of MACE (13.7% vs 6.4%,P<0.05) and TVR (9.8% vs 4.0%,P<0.05) and the cumulative MACE free survival rate was very significantly lower in the DM group (86.4% vs 93:6%,P<0.05).ST occurred in 7 patients (1.4%) at the end of 3 years' follow-up,5 of them had definite ST with 4 cases presenting with myocardial reinfarction and 1 with unstable angina,the other 2 with probable ST had reinfarction in the stented coronary territory without angiographic follow-up.There was no difference in occurrence of ST between off label (1.5%) and on label groups (1.1%,P=0.07).Conclusions In daily practice,about 2/3 of patients were treated by Firebird SES by off label indications.Medium term clinical follow-up of 3 years indicated CAD patients treated by Firebird SES had a low MACE and acceptable ST rate.DM patients had higher rates of adverse events and than non DM.

  3. Current models of care for disorders of sex development - results from an International survey of specialist centres

    DEFF Research Database (Denmark)

    Kyriakou, Andreas; Dessens, Arianne; Bryce, Jillian

    2016-01-01

    BACKGROUND: To explore the current models of practice in centres delivering specialist care for children with disorders of sex development (DSD), an international survey of 124 clinicians, identified through DSDnet and the I-DSD Registry, was performed in the last quarter of 2014. RESULTS: A total...... a local DSD registry and 40 (53 %) shared their data in a multicentre DSD registry. Attendance in local, national and international DSD-related educational programs was reported by 69, 78 and 84 % clinicians, respectively. Participation in audits/quality improvement exercises in DSD care was reported...... hydroxysteroid dehydrogenase 3 deficiency by 50 and 55 % clinicians, respectively. CONCLUSION: DSD centres report a high level of interaction at an international level, have access to specialist staff and are increasingly relying on molecular genetics for routine diagnostics. The quality of care provided...

  4. The WiFeS S7 AGN survey: Current status and recent results on NGC 6300

    CERN Document Server

    Scharwächter, J; Shastri, P; Davies, R; Kewley, L; Hampton, E; Sutherland, R; Kharb, P; Jose, J; Bhatt, H; Ramya, S; Jin, C; Banfield, J; Zaw, I; Juneau, S; James, B; Srivastava, S

    2015-01-01

    The Siding Spring Southern Seyfert Spectroscopic Snapshot Survey (S7) is a targeted survey probing the narrow-line regions (NLRs) of a representative sample of ~140 nearby (z<0.02) Seyfert galaxies by means of optical integral field spectroscopy. The survey is based on a homogeneous data set observed using the Wide Field Spectrograph WiFeS. The data provide a 25x38 arcsec$^2$ field-of-view around the galaxy centre at typically ~1.5 arcsec spatial resolution and cover a wavelength range between ~3400 - 7100 $\\AA$ at spectral resolutions of ~100 km s$^{-1}$ and ~50 km s$^{-1}$ in the blue and red parts, respectively. The survey is primarily designed to study gas excitation and star formation around AGN, with a special focus on the shape of the AGN ionising continuum, the interaction between radio jets and the NLR gas, and the nature of nuclear LINER emission. We provide an overview of the current status of S7-based results and present new results for NGC 6300.

  5. Current state of musculoskeletal ultrasound training and implementation in Europe: results of a survey of experts and scientific societies

    DEFF Research Database (Denmark)

    Naredo, Esperanza; D'Agostino, Maria A; Conaghan, Philip G

    2010-01-01

    To document the current state of musculoskeletal US (MSUS) training and extent of implementation among rheumatologists in the member countries of EULAR.......To document the current state of musculoskeletal US (MSUS) training and extent of implementation among rheumatologists in the member countries of EULAR....

  6. Determination of High-Frequency Current Distribution Using EMTP-Based Transmission Line Models with Resulting Radiated Electromagnetic Fields

    Energy Technology Data Exchange (ETDEWEB)

    Mork, B; Nelson, R; Kirkendall, B; Stenvig, N

    2009-11-30

    Application of BPL technologies to existing overhead high-voltage power lines would benefit greatly from improved simulation tools capable of predicting performance - such as the electromagnetic fields radiated from such lines. Existing EMTP-based frequency-dependent line models are attractive since their parameters are derived from physical design dimensions which are easily obtained. However, to calculate the radiated electromagnetic fields, detailed current distributions need to be determined. This paper presents a method of using EMTP line models to determine the current distribution on the lines, as well as a technique for using these current distributions to determine the radiated electromagnetic fields.

  7. Summary of Recent Results from NASA's Space Solar Power (SSP) Programs and the Current Capabilities of Microwave WPT Technology

    Science.gov (United States)

    McSpadden, James; Mankins, John C.; Howell, Joe T. (Technical Monitor)

    2002-01-01

    The concept of placing enormous solar power satellite (SPS) systems in space represents one of a handful of new technological options that might provide large-scale, environmentally clean base load power into terrestrial markets. In the US, the SPS concept was examined extensively during the late 1970s by the U.S. Department of Energy (DOE) and the National Aeronautics and Space Administration (NASA). More recently, the subject of space solar power (SSP) was reexamined by NASA from 1995-1997 in the "fresh look" study, and during 1998 in an SSP "concept definition study". As a result of these efforts, in 1999-2000, NASA undertook the SSP Exploratory Research and Technology (SERT) program which pursued preliminary strategic technology research and development to enable large, multi-megawatt SSP systems and wireless power transmission (WPT) for government missions and commercial markets (in-space and terrestrial). During 2001-2002, NASA has been pursuing an SSP Concept and Technology Maturation (SCTM) program follow-on to the SERT, with special emphasis on identifying new, high-leverage technologies that might advanced the feasibility of future SSP systems. In addition, in 2001, the U.S. National Research Council (NRC) released a major report providing the results of a peer review of NASA's SSP strategic research and technology (R&T) road maps. One of the key technologies needed to enable the future feasibility of SSP/SPS is that of wireless power transmission. Advances in phased array antennas and rectennas have provided the building blocks for a realizable WPT system. These key components include the dc-RF converters in the transmitter, the retrodirective beam control system, and the receiving rectenna. Each subject is briefly covered, and results from the SERT program that studied a 5.8 GHz SPS system are presented. This paper presents a summary results from NASA's SSP efforts, along with a summary of the status of microwave WPT technology development.

  8. Magnetic field structure of Saturn's dayside magnetosphere and its mapping to the ionosphere: Results from ring current modeling

    Science.gov (United States)

    Bunce, E. J.; Arridge, C. S.; Cowley, S. W. H.; Dougherty, M. K.

    2008-02-01

    Ring current modeling in Saturn's magnetosphere using Pioneer-11, Voyager, and Cassini data has shown that the size and strength of the current system grows with the extension of the magnetosphere, governed by the solar wind dynamic pressure. Here we show that the consequent middle magnetosphere field is quasi-dipolar in form when the magnetosphere is strongly compressed, but extends into a magnetodisc when it is strongly expanded. We also show that the region occupied by the modeled ring current corresponds to an essentially fixed shell of field lines that expands and contracts with the size of the system, thus mapping to an almost fixed co-latitude range in Saturn's ionosphere, between ~14° and ~20° in the northern hemisphere, and ~16° and ~22° in the southern hemisphere. The median dayside UV auroral oval is found to map from near the poleward edge of the modeled ring current toward the boundary of open field lines at smaller co-latitudes. In the equatorial plane this corresponds to a layer ~2-5 Saturn radius wide (depending on magnetosphere size), extending from near the outer edge of the ring current to the vicinity of the magnetopause.

  9. A Study of Current Trends and Issues for Graphics Education: Results from a Five-Year Follow-Up Survey

    Science.gov (United States)

    Clark, Aaron C.; Scales, Alice Y.

    2006-01-01

    During the 1998-1999 academic year, a survey was conducted to look at current trends and issues in the profession of graphics education (Clark & Scales, 1999). The survey solicited information from the membership of the Engineering Design Graphics Division of the American Society for Engineering Education related to their view of future areas of…

  10. Prenatal protein malnutrition results in increased frequency of miniature inhibitory postsynaptic currents in rat CA3 interneurons.

    Science.gov (United States)

    Chang, Yu-Ming; Galler, Janina R; Luebke, Jennifer I

    2003-08-01

    Electrophysiological studies have revealed an increase in the level of tonic inhibition in the hippocampus following prenatal protein malnutrition in rats. In the present study, whole cell patch clamp recordings of bipolar interneurons in the stratum radiatum of the CA3 subfield were used to determine whether this increase in inhibition can be accounted for by a change in the electrophysiological properties of GABAergic interneurons. Hippocampal slices were prepared from juvenile rats whose dams were fed either a normal (25% casein) or low (6% casein) protein diet throughout pregnancy. Intrinsic membrane and action potential properties were unaltered by the prenatal nutritional insult. In most respects the characteristics of GABAA receptor-mediated inhibitory postsynaptic currents (IPSCs) and the modulation of such currents by the benzodiazepine agonist zolpidem were also similar in cells from the two nutritional groups. While the frequency of spontaneous inhibitory currents was unaltered, miniature (Tetrodotoxin resistant) inhibitory currents occurred at a significantly increased frequency in interneurons from prenatally protein malnourished rats. Thus, while the basic membrane properties of interneurons are preserved, there is a significant increase in the probability of GABA release from interneurons following prenatal protein malnutrition.

  11. NOAA/EcoFOCI Chukchi Sea ADCP Mooring time-series data, stations C1, C2, and C3, 2010-08-29 to 2012-08-22, including zonal (U) and meridional (V) current measurements. (NCEI Accession 0149848)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — These Acoustic Doppler Current Profiler (ADCP) time-series data sets, consist of zonal current (U) and meridional current (V) measurements from moored instruments at...

  12. Preliminary results concerning the simulation of beam profiles from extracted ion current distributions for mini-STRIKE

    Energy Technology Data Exchange (ETDEWEB)

    Agostinetti, P., E-mail: piero.agostinetti@igi.cnr.it; Serianni, G.; Veltri, P. [Consorzio RFX (CNR, ENEA, INFN, Università di Padova, Acciaierie Venete SpA), Corso Stati Uniti 4, 35127 Padova (Italy); Giacomin, M. [Physics Department, Università di Padova, via F. Marzolo 8, 35131 Padova (Italy); Bonomo, F.; Schiesko, L. [Max-Planck-Institut für Plasmaphysik, Boltzmannstrasse 2, D-85748 Garching (Germany)

    2016-02-15

    The Radio Frequency (RF) negative hydrogen ion source prototype has been chosen for the ITER neutral beam injectors due to its optimal performances and easier maintenance demonstrated at Max-Planck-Institut für Plasmaphysik, Garching in hydrogen and deuterium. One of the key information to better understand the operating behavior of the RF ion sources is the extracted negative ion current density distribution. This distribution—influenced by several factors like source geometry, particle drifts inside the source, cesium distribution, and layout of cesium ovens—is not straightforward to be evaluated. The main outcome of the present contribution is the development of a minimization method to estimate the extracted current distribution using the footprint of the beam recorded with mini-STRIKE (Short-Time Retractable Instrumented Kalorimeter). To accomplish this, a series of four computational models have been set up, where the output of a model is the input of the following one. These models compute the optics of the ion beam, evaluate the distribution of the heat deposited on the mini-STRIKE diagnostic calorimeter, and finally give an estimate of the temperature distribution on the back of mini-STRIKE. Several iterations with different extracted current profiles are necessary to give an estimate of the profile most compatible with the experimental data. A first test of the application of the method to the BAvarian Test Machine for Negative ions beam is given.

  13. Massless correlators of vector, scalar and tensor currents in position space at orders alpha_s^3 and alpha_s^4: explicit analytical results

    OpenAIRE

    Chetyrkin, K. G.; Maier, A

    2010-01-01

    We present analytical results both in momentum and position space for the massless correlators of the vector and scalar currents to order alpha_s^4 as well as for the tensor currents to order alpha_s^3. The evolution equations for the correlators together with all relevant anomalous dimensions are discussed in detail. As an application we present explicit conversion formulas relating the MSbar-renormalized vector, scalar and tensor currents to their counterparts renormalized in the X-space re...

  14. Molecular dynamics simulations of metallic friction and of its dependence on electric currents - development and first results

    Science.gov (United States)

    Meintanis, Evangelos Anastasios

    We have extended the HOLA molecular dynamics (MD) code to run slider-on-block friction experiments for Al and Cu. Both objects are allowed to evolve freely and show marked deformation despite the hardness difference. We recover realistic coefficients of friction and verify the importance of cold-welding and plastic deformations in dry sliding friction. Our first data also show a mechanism for decoupling between load and friction at high velocities. Such a mechanism can explain an increase in the coefficient of friction of metals with velocity. The study of the effects of currents on our system required the development of a suitable electrodynamic (ED) solver, as the disparity of MD and ED time scales threatened the efficiency of our code. Our first simulations combining ED and MD are presented.

  15. Engineering change management report 2012: Survey results on causes and effects, current practice, problems, and strategies in Brazil

    DEFF Research Database (Denmark)

    Chucholowski, Nepomuk; Langer, Stefan; Ferreira, Marcelo Gitirana Gomes

    management of engineering changes is a crucial precondition for Brazilian companies to successfully compete not only on the fast growing Brazilian market, but also on the world market which becomes more interesting due to the rising industrial power of Brazil. To achieve improvements in engineering change...... management practice, industry and universities need to work together. In this report the main findings of our study on Engineering Change Management (ECM) in Brazilian companies are presented, which indicate possible solution strategies and further research needs. Our survey aimed on the investigation...... of current practice, the biggest challenges and potential strategies of engineering change management. A total of 55 Brazilian companies from a broad range of industry sectors and company sizes participated from December 2011 until January 2012 in the survey which was elaborated and conducted by members...

  16. Recent experimental results of effects of perfluoroalkyl substances in laboratory animals - Relation to current regulations and guidance values.

    Science.gov (United States)

    Lilienthal, Hellmuth; Dieter, Hermann H; Hölzer, Jürgen; Wilhelm, Michael

    2017-03-02

    The detection of perfluoroalkyl substances (PFAS) in surface and drinking water from various countries raised the attention to the presence of these chemicals in environmental probes and led to several regulatory actions to limit exposure in human beings. There was particular concern about perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS), due to their former wide-spread use. Recently, several institutions published revisions of former regulatory or recommended maximum concentrations in drinking water and food, which are markedly lower than the former values. The present short overview describes the current regulations for PFAS and compares them with the outcome of several experimental studies in laboratory animals at low-level exposure to PFOA and PFOS. In addition, regulations for short-chain PFAS are presented which, due to lack of toxicological information, are evaluated according to the concepts of Threshold of Toxicological Concern (TTC) or the Health-related Indication Values (HRIV).

  17. The value of the internship for radiation oncology training: results of a survey of current and recent trainees.

    Science.gov (United States)

    Baker, Stephen R; Romero, Michelle J; Geannette, Christian; Patel, Amish

    2009-07-15

    Although a 12-month clinical internship is the traditional precursor to a radiation oncology residency, the continuance of this mandated training sequence has been questioned. This study was performed to evaluate the perceptions of current radiation oncology residents with respect to the value of their internship experience. A survey was sent to all US radiation oncology residents. Each was queried about whether they considered the internship to be a necessary prerequisite for a career as a radiation oncologist and as a physician. Preferences were listed on a Likert scale (1 = not at all necessary to 5 = absolutely necessary). Seventy-one percent considered the internship year mostly (Likert Scale 4) or absolutely necessary (Likert Scale 5) for their development as a radiation oncologist, whereas 19.1% answered hardly or not at all (Likert Scale 2 and 1, respectively). With respect to their collective considerations about the impact of the internship year on their development as a physician, 89% had a positive response, 5.8% had a negative response, and 4.7% had no opinion. Although both deemed the preliminary year favorably, affirmative answers were more frequent among erstwhile internal medicine interns than former transitional program interns. A majority of radiation oncology residents positively acknowledged their internship for their development as a specialist and an even greater majority valued it for their development as a physician. This affirmative opinion was registered more frequently by those completing an internal medicine internship compared with a transitional internship.

  18. Rapid and reliable seismic source characterization in earthquake early warning systems: current methodologies, results, and new perspectives

    Science.gov (United States)

    Colombelli, Simona; Zollo, Aldo

    2016-10-01

    In the present paper, we provided a review of the main principles and methodologies on which the current earthquake early warning systems are grounded and will also provide a perspective view for next future developments and improvements. First, we introduce the standard methodologies for the source characterization in earthquake early warning, with a special focus on the real-time earthquake magnitude determination. We discuss the suitability of existent methodologies and empirical regression laws for very large events. We then present the different approaches for the rapid prediction of the ground shaking and of the potential damaged zone, both based on traditional seismic data and on the use of continuous GPS data. Finally, the last part of the paper provides the perspective view toward a next generation of early warning systems, linking new research achievements about the earthquake rupture nucleation and the development of new methods/technologies aimed at a fast and high-resolution, real-time modeling of the ongoing source process and accurate prediction of the quake shaking at the regional and local scale.

  19. The first Italian Superconducting Fault Current Limiter: Results of the field testing experience after one year operation

    Science.gov (United States)

    Martini, L.; Bocchi, M.; Ascade, M.; Valzasina, A.; Rossi, V.; Ravetta, C.; Angeli, G.

    2014-05-01

    Ricerca sul Sistema Energetico S.p.A. (RSE) has been gaining a relevant experience in the simulation, design and installation of resistive-type Superconducting Fault Current Limiter (SFCL) devices for more than five years in the framework of a R&D national project funded by the Ricerca di Sistema (RdS). The most recent outcome of this research activity is the installation of a resistive-type BSCCO-based 9 kV / 3.4 MVA SFCL device in a single feeder branch of the Medium Voltage (MV) distribution network managed by A2A Reti Elettriche S.p.A (A2A) in the Milano area. This installation represents the first SFCL successfully installed in Italy. In this paper, we report on the main outcomes after a more than 1-year long steady-state field testing activity. The design of an upgraded device to be installed in the same substation has already been initiated: the new SFCL will allow to protect four different feeders, therefore implying a device upgrade up to 15.6 MVA.

  20. An Assessment of the Current US Radiation Oncology Workforce: Methodology and Global Results of the American Society for Radiation Oncology 2012 Workforce Study

    Energy Technology Data Exchange (ETDEWEB)

    Vichare, Anushree; Washington, Raynard; Patton, Caroline; Arnone, Anna [ASTRO, Fairfax, Virginia (United States); Olsen, Christine [Massachusetts General Hospital, Boston, Massachusetts, (United States); Fung, Claire Y. [Commonwealth Newburyport Cancer Center, Newburyport, Massachusetts (United States); Hopkins, Shane [William R. Bliss Cancer Center, Ames, Iowa (United States); Pohar, Surjeet, E-mail: spohar@netzero.net [Indiana University Health Cancer Center East, Indiana University, Indianapolis, Indiana (United States)

    2013-12-01

    Purpose: To determine the characteristics, needs, and concerns of the current radiation oncology workforce, evaluate best practices and opportunities for improving quality and safety, and assess what we can predict about the future workforce. Methods and Materials: An online survey was distributed to 35,204 respondents from all segments of the radiation oncology workforce, including radiation oncologists, residents, medical dosimetrists, radiation therapists, medical physicists, nurse practitioners, nurses, physician assistants, and practice managers/administrators. The survey was disseminated by the American Society for Radiation Oncology (ASTRO) together with specialty societies representing other workforce segments. An overview of the methods and global results is presented in this paper. Results: A total of 6765 completed surveys were received, a response rate of 19%, and the final analysis included 5257 respondents. Three-quarters of the radiation oncologists, residents, and physicists who responded were male, in contrast to the other segments in which two-thirds or more were female. The majority of respondents (58%) indicated they were hospital-based, whereas 40% practiced in a free-standing/satellite clinic and 2% in another setting. Among the practices represented in the survey, 21.5% were academic, 25.2% were hospital, and 53.3% were private. A perceived oversupply of professionals relative to demand was reported by the physicist, dosimetrist, and radiation therapist segments. An undersupply was perceived by physician's assistants, nurse practitioners, and nurses. The supply of radiation oncologists and residents was considered balanced. Conclusions: This survey was unique as it attempted to comprehensively assess the radiation oncology workforce by directly surveying each segment. The results suggest there is potential to improve the diversity of the workforce and optimize the supply of the workforce segments. The survey also provides a benchmark for

  1. Variability in wave refraction and resultant nearshore current patterns: Exposed versus sheltered beaches along north Karnataka, west coast of India

    Digital Repository Service at National Institute of Oceanography (India)

    Veerayya, M.; Pankajakshan, T.

    For predominant waves approaching from directions varying between SW and WNW and periods varying from 6 to 11 sec, the refraction function (Kd) shows amplification of wave heights resulting in concentration of wave energy on headlands and reduction...

  2. Current results of an arachnological survey of some sandstone rock sites in Bohemia (so-called "rock cities"

    Directory of Open Access Journals (Sweden)

    Růžička, Vlastimil

    1992-07-01

    Full Text Available The spider fauna of the Adrspach-Teplice rockswas investigated. Some records on spider fauna of other nine sandstone rock areas are included. The phenomenon of "rock cities" manifests itself in three aspects: (1 In the bottom parts are microclimatically cold spaces, frequently hosting northern ot mountain species of invertebrates, which here have an azonal occurence. (2 the sun exposed tops of rocks can host thermophilous species. (3 Some species are limited to the surface of rocks and boulders. These are referred to as lithophilous or lithobiont species.

  3. Thermodiffusion in concentrated ferrofluids: A review and current experimental and numerical results on non-magnetic thermodiffusion

    Energy Technology Data Exchange (ETDEWEB)

    Sprenger, Lisa, E-mail: Lisa.Sprenger@tu-dresden.de; Lange, Adrian; Odenbach, Stefan [Institute of Fluid Mechanics, Chair of Magnetofluiddynamics, Measuring and Automation Technology, TU Dresden, 01062 Dresden (Germany)

    2013-12-15

    Ferrofluids are colloidal suspensions consisting of magnetic nanoparticles dispersed in a carrier liquid. Their thermodiffusive behaviour is rather strong compared to molecular binary mixtures, leading to a Soret coefficient (S{sub T}) of 0.16 K{sup −1}. Former experiments with dilute magnetic fluids have been done with thermogravitational columns or horizontal thermodiffusion cells by different research groups. Considering the horizontal thermodiffusion cell, a former analytical approach has been used to solve the phenomenological diffusion equation in one dimension assuming a constant concentration gradient over the cell's height. The current experimental work is based on the horizontal separation cell and emphasises the comparison of the concentration development in different concentrated magnetic fluids and at different temperature gradients. The ferrofluid investigated is the kerosene-based EMG905 (Ferrotec) to be compared with the APG513A (Ferrotec), both containing magnetite nanoparticles. The experiments prove that the separation process linearly depends on the temperature gradient and that a constant concentration gradient develops in the setup due to the separation. Analytical one dimensional and numerical three dimensional approaches to solve the diffusion equation are derived to be compared with the solution used so far for dilute fluids to see if formerly made assumptions also hold for higher concentrated fluids. Both, the analytical and numerical solutions, either in a phenomenological or a thermodynamic description, are able to reproduce the separation signal gained from the experiments. The Soret coefficient can then be determined to 0.184 K{sup −1} in the analytical case and 0.29 K{sup −1} in the numerical case. Former theoretical approaches for dilute magnetic fluids underestimate the strength of the separation in the case of a concentrated ferrofluid.

  4. Transcorneal alternating current stimulation after severe axon damage in rats results in "long-term silent survivor" neurons.

    Science.gov (United States)

    Henrich-Noack, Petra; Lazik, Stefanie; Sergeeva, Elena; Wagner, Sebastian; Voigt, Nadine; Prilloff, Sylvia; Fedorov, Anton; Sabel, Bernhard A

    2013-06-01

    Transcorneal alternating current stimulation (tACS) was proposed to decrease acute death of retinal ganglion cells after optic nerve transection in rats, but it is not known if cell survival is long-term and associated with functional restoration. We therefore evaluated the effects of tACS in a rat model of optic nerve crush using anatomical, electrophysiological and behavioural measures. Rats were trained in a brightness discrimination visual task and the retinal ganglion cell number was quantified with in vivo confocal neuroimaging. Thereafter, severe optic nerve crush or sham crush was performed and rats were treated under anaesthesia either with tACS or sham stimulation immediately after the lesion and on day 3, 7, 11, 15, 19 and 23. Brightness discrimination was evaluated for 6 weeks and retinal ganglion cells were counted in vivo on post-crush days 7 and 28. In additional rats we studied the influence of tACS on bioelectrical activity. On post-lesion day 28, the tACS-treated group showed a neuronal survival of 28.2% which was significantly greater than in sham operates (8.6%). All animals with optic nerve crush were significantly impaired in brightness discrimination and did not recover performance, irrespective to which group they belonged. In accordance with this, there was no significant influence of the stimulation on EEG power spectra. In conclusion, tACS induced long-term neuronal protection from delayed retrograde cell death, but in this case of severe axonal damage tACS did not influence functional restoration and EEG signals recorded over the visual cortex.

  5. THE CURRENT STATE OF THE PROBLEM OF CHILDREN HEALTH BORN IN RESULT OF THE ASSISTED REPRODUCTIVE TECHNOLOGIES

    Directory of Open Access Journals (Sweden)

    V.O. Mansimova

    2011-01-01

    Full Text Available A brief historical background of development of the assisted reproductive technologies (ART is presented. The works of russian and foreign authors about the neonatal period, the health of babies born in result of different methods of ART (in vitro fertilization using ICSI were analyzed. After discussion there were indicated new approaches for prevention of perinatal morbidity and ensuring harmonious development and quality of life for these children. The necessity of a national multicenter study of the status of children born in result of induced pregnancy was proved.Key words: assisted reproductive technologies, IVF, ICSI technique, newborns, health.

  6. Augmentation of spelling therapy with transcranial direct current stimulation in primary progressive aphasia: Preliminary results and challenges.

    Science.gov (United States)

    Tsapkini, Kyrana; Frangakis, Constantine; Gomez, Yessenia; Davis, Cameron; Hillis, Argye E

    Primary progressive aphasia (PPA) is a neurodegenerative disease that primarily affects language functions and often begins in the fifth or sixth decade of life. The devastating effects on work and family life call for the investigation of treatment alternatives. In this article, we present new data indicating that neuromodulatory treatment, using transcranial direct current stimulation (tDCS) combined with a spelling intervention, shows some promise for maintaining or even improving language, at least temporarily, in PPA. The main aim of the present article is to determine whether tDCS plus spelling intervention is more effective than spelling intervention alone in treating written language in PPA. We also asked whether the effects of tDCS are sustained longer than the effects of spelling intervention alone. We present data from six PPA participants who underwent anodal tDCS or sham plus spelling intervention in a within-subject crossover design. Each stimulation condition lasted 3 weeks or a total of 15 sessions with a 2-month interval in between. Participants were evaluated on treatment tasks as well as on other language and cognitive tasks at 2-week and 2-month follow-up intervals after each stimulation condition. All participants showed improvement in spelling (with sham or tDCS). There was no difference in the treated items between the two conditions. There was, however, consistent and significant improvement for untrained items only in the tDCS plus spelling intervention condition. Furthermore, the improvement lasted longer in the tDCS plus spelling intervention condition compared to sham plus spelling intervention condition. Neuromodulation with tDCS offers promise as a means of augmenting language therapy to improve written language function at least temporarily in PPA. The consistent finding of generalisation of treatment benefits to untreated items and the superior sustainability of treatment effects with tDCS justifies further investigations. However

  7. Current status of health among workers in Japan: Results from the Japan Epidemiology Collaboration on Occupational Health Study.

    Science.gov (United States)

    Kuwahara, Keisuke; Uehara, Akihiko; Yamamoto, Makoto; Nakagawa, Tohru; Honda, Toru; Yamamoto, Shuichiro; Okazaki, Hiroko; Sasaki, Naoko; Ogasawara, Takayuki; Hori, Ai; Nishiura, Chihiro; Miyamoto, Toshiaki; Kochi, Takeshi; Eguchi, Masafumi; Tomita, Kentaro; Imai, Teppei; Nishihara, Akiko; Nagahama, Satsue; Murakami, Taizo; Shimizu, Makiko; Kabe, Isamu; Mizoue, Tetsuya; Kunugita, Naoki; Sone, Tomofumi; Dohi, Seitaro

    2016-12-07

    Data are limited on the sex-specific prevalence of diseases and their risk factors in middle-aged and older workers in Japan. In this cross-sectional study, we investigated the age- and sex-specific prevalence of hypertension, diabetes, dyslipidemia, metabolic syndrome (defined using joint statement criteria), obesity, underweight, abdominal obesity, and smoking among approximately 70,000 to 90,000 Japanese workers (predominantly men) aged 20-69 years in 2014. We also investigated the prevalence of low cardiorespiratory fitness in 2012 and no leisure-time exercise in 2014. In both sexes, the prevalence of lifestyle-related risk factors, including hypertension, diabetes, dyslipidemia, metabolic syndrome, obesity, and abdominal obesity, was increased with aging. In contrast, the prevalence of underweight was decreased with aging. Smoking prevalence exceeded 30% in men regardless of age, whereas the prevalence was around 10% in women of all age groups. Prevalence of no leisure-time exercise exceeded 50% among middle-aged and older workers in both sexes. Among workers aged 50-64 years, less than half of men had low fitness, whereas more than half of women had low fitness. Given the high prevalence of lifestyle-related risk factors among middle-aged and older workers, effective strategies to prevent cardiovascular disease in this age group are needed in Japan.

  8. Current research results on the technical basis for environmental qualification of safety-related digital I and C systems

    Energy Technology Data Exchange (ETDEWEB)

    Korsah, K.; Ewing, P.D.; Kercel, S.; Wood, R.T. [Oak Ridge National Lab., TN (United States); Hassan, M. [Brookhaven National Lab., Upton, NY (United States); Tanaka, T. [Sandia National Labs., Albuquerque, NM (United States); Antonescu, C. [Nuclear Regulatory Commission, Rockville, MD (United States)

    1998-04-01

    This paper presents results to date of an NRC-sponsored confirmatory research program initiated at three national laboratories to address environmental compatibility/qualification concerns associated with the use of microprocessor-based safety-related instrumentation and control (I and C) systems in nuclear power plants. The research approach involved evaluating existing military and industrial guidance, identifying the most significant environmental stressors and, for advanced I and C systems in a nuclear power plant, investigating the likely failure modes--both at the integrated circuit and system level--for digital technologies under varying levels of environmental stress (such as smoke exposure and electromagnetic and radio-frequency interference). The insights gained from these studies are being used to recommend appropriate methods for qualifying safety-related digital equipment in nuclear power plants.

  9. Comparison of the Effect of Vaginal Zataria multiflora Cream and Oral Metronidazole Pill on Results of Treatments for Vaginal Infections including Trichomoniasis and Bacterial Vaginosis in Women of Reproductive Age

    OpenAIRE

    Abdali, Khadijeh; Jahed, Leila; Amooee, Sedigheh; Zarshenas, Mahnaz; Tabatabaee, Hamidreza; Bekhradi, Reza

    2015-01-01

    Effect of Zataria multiflora on bacterial vaginosis and Trichomonas vaginalis is shown in vivo and in vitro. We compare the effectiveness of Zataria multiflora cream and oral metronidazole pill on results of treatment for vaginal infections including Trichomonas and bacterial vaginosis; these infections occur simultaneously. The study included 420 women with bacterial vaginosis, Trichomonas vaginalis, or both infections together, who were randomly divided into six groups. Criteria for diagnos...

  10. Energy+ pumps - Technology procurement for very energy efficient circulation pumps, first results of the current IEE-project

    Energy Technology Data Exchange (ETDEWEB)

    Barthel, Claus; Thomas, Stefan [Wuppertal Inst. for Climate, Environment, Energy (Germany); Benke, Georg; Schaeppi, Bernd [Austrian Energy Agency A.E.A (Austria); Forfori, Fabio [Politecnico di Milano, Dept. di Energetica (Italy); Guisson, Ruben [Flemisch Inst. for technological research (Vito) (Belgium); Papamikrouli, Louiza [Centre for Renewable Energy Sources (CRES) (Greece); Puente, Margarita [ESCAN, S.A. (Spain); Spirek, Tomas [SEVEn, Stredisko pro efektivni vyuzivani energie, o.p.s. (Czech Republic); Rautiainen, Kimmo [Motiva Oy (Finland); Koehl, Joerg [Deutsche Energie-Agentur GmbH (Germany); Anglade, Alain [ADEME (France); Nipkow, Juerg [ARENA (Switzerland)

    2007-07-01

    About 2 % of the overall electricity consumption of the EU is caused by circulators in single or double family homes and flats. A new technology of pumps with electronically commutated (EC) motor pumps is available now; it is one possible way to achieve a reduction in circulator annual electricity use by 60 % or more.The project's objective is a market transformation towards this new very energy-efficient pump technologies - Energy+ pumps - for circulators in heating systems, both stand alone and integrated in boilers. Only few manufacturers have so far introduced the new pump technology to the market for single or double family homes and flats.To bring more products to the market from all major manufacturers, the project will adapt and apply the technology procurement methodology as it was very successfully tested in the European Energy+ project on energy-efficient cold appliances [5] [6]. Large buyers will be aggregated, to activate the pump and boiler manufacturers. Sales and training materials and a sizing spreadsheet software for installation contractors will be developed and applied. A competition both for energy-efficient products and marketing campaigns will be organised and the information on the Energy+ pumps will be disseminated widely through website, newsletter, media, and fairs.This paper gives a short overview of this project and presents the results of the first project phases: a European wide market study on circulators and heating systems, and the first Energy+ lists for circulators, buyers and supporters.

  11. Current evaluation of sonography of the meniscus. Results of a comparative study of sonographic and arthroscopic findings.

    Science.gov (United States)

    Casser, H R; Sohn, C; Kiekenbeck, A

    1990-01-01

    Sonography of the knee has gained in significance in the diagnosis of the meniscus; experimental and clinical studies have demonstrated that the normal and pathological anatomy of the meniscus can be visualized on a sonogram. The aim of this comparative investigation is to evaluate sonographic lesion diagnosis in comparison with arthroscopic findings, using a standardized examination method. Two hundred and six knee joints were first scanned sonographically using a 7.5 MHz sector transducer. The examining doctor had neither anamnestic nor clinical information in advance. On the following day, the joints were examined arthroscopically, without the findings of the day before being available to the examiner. When the findings were compared, the sensitivity of sonographic diagnosis of lesions was found to be 82.2% and its specificity 87.6%. The patients were of varying ages and had varying anamneses. The results show that sonography of the meniscus is a valuable diagnostic help when the knee-joint symptoms are not clear, given that the correct technical equipment and sufficient experience with this form of examination are at hand. The advantage of sonography is that, in contrast to arthroscopy, it is noninvasive and easily available.

  12. Semi-inclusive DIS Experiments Using Transversely Polarized Targets in Hall-A: Current Results and Future Plans

    Directory of Open Access Journals (Sweden)

    Allada Kalyan

    2012-12-01

    Full Text Available Measurement of single (SSA and double spin asymmetries (DSA in semiinclusive DIS reactions using polarized targets provide a powerful method to probe transverse momentum dependent parton distribution functions (TMDs. In particular, the experimentally measured SSA on nucleon targets can help in extracting the transversity and Sivers distribution functions of u and d-quarks. Similarly, the measured DSA are sensitive to the quark spin-orbital correlations, and provide an access to the TMD parton distribution function (g1T. A recent experiment conducted in Hall-A Jefferson Lab using transversely polarized 3He provide first such measurements on “effective” neutron target. The measurement was performed using 5.9 GeV beam from CEBAF and measured the target SSA/DSA in the SIDIS reaction 3He↑(e, e′π±X. The kinematical range, x = 0.19 ~ 0.34, at Q2 = 1.77 ~ 2.73 (GeV/c2, was focused on the valence quark region. The results from this measurement along with our plans for future high precision measurements in Hall-A are presented.

  13. Numerical evaluation of currents induced in a worker by ELF non-uniform electric fields in high voltage substations and comparison with experimental results.

    Science.gov (United States)

    Tarao, Hiroo; Korpinen, Leena H; Kuisti, Harri A; Hayashi, Noriyuki; Elovaara, Jarmo A; Isaka, Katsuo

    2013-01-01

    An ungrounded human, such as a substation worker, receives contact currents when touching a grounded object in electric fields. In this article, contact currents and internal electric fields induced in the human when exposed to non-uniform electric fields at 50 Hz are numerically calculated. This is done using a realistic human model standing at a distance of 0.1-0.5 m from the grounded conductive object. We found that the relationship between the external electric field strength and the contact current obtained by calculation is in good agreement with previous measurements. Calculated results show that the contact currents largely depend on the distance, and that the induced electric fields in the tissues are proportional to the contact current regardless of the non-uniformity of the external electric field. Therefore, it is concluded that the contact current, rather than the spatial average of the external electric field, is more suitable for evaluating electric field dosimetry of tissues. The maximum induced electric field appears in the spinal cord in the central nervous system tissues, with the induced electric field in the spinal cord approaching the basic restriction (100 mV/m) of the new 2010 International Commission on Non-Ionizing Radiation Protection guidelines for occupational exposure, if the contact current is 0.5 mA. Copyright © 2012 Wiley Periodicals, Inc.

  14. RESULTS OF CALCULATION-EXPERIMENTAL INVESTIGATIONS OF ELECTRO-THERMAL RESISTIBILITY OF SHEET STEEL SAMPLES TO ACTION OF RATIONED COMPONENTS OF PULSED CURRENT OF ARTIFICIAL LIGHTING

    Directory of Open Access Journals (Sweden)

    M.I. Baranov

    2016-06-01

    Full Text Available Purpose. Calculation and experimental researches of the electro-thermal resistibility of the steel sheet samples to action standard pulse current components of the artificial lightning with amplitude-time parameters (ATP, corresponded the requirements of normative documents of USA for SAE ARP 5412 & SAE ARP 5416. Methodology. Electrophysics bases of technique of high tensions and large impulsive currents (LIC, and also scientific and technical bases of planning of devices of high-voltage impulsive technique and measuring in them LIC. Сurrent amplitude ImA=±200 kA (with a tolerance of ±10 %; current action integral JA=2∙106 A2•s (with a tolerance of ±20 %; time, corresponding to the amplitude of the current ImA, tmA≤50 microseconds; the duration of the current flow τpA≤500 microseconds. Results. The results of the evaluation of the calculated and experimental studies of electro-thermal resistance of the samples of plates measuring 0,5 m  0,5 m stainless steel 1 mm thickness to the action on them artificial lightning impulse currents with rationed ATP on the requirements of normative documents of USA for SAE ARP 5412 & SAE ARP 5416. A pulse A- component have a first amplitude 192 kA, the corresponding time of 34 μs, and the duration aperiodic component amplitude 804 A, corresponding to the time 9 ms. It has been shown that the long C- component current of artificial lightning can lead to keyhole these samples. The diameter of the holes in this thin steel sheet, which is formed during the flow of current C- components can reach 15 mm. The results of calculation and experiment agree within 28 %. Originality. For the first time in world practice on the generator large pulsed currents experimental studies of resistibility of sheet steel samples to the action of artificial lightning currents with critical parameters. Practical value. Using the results obtained in the practice of lightning protection will significantly improve the

  15. Cell Phones: Current Research Results

    Science.gov (United States)

    ... Potential Biological or Adverse Health Effects of Wireless Communication Devices World Health Organization: Electromagnetic Fields and Public Health: Mobile Phones International Agency for Research on Cancer Press ...

  16. Factors Associated With Current Smoking Among Off-Reserve First Nations and Métis Youth: Results From the 2012 Aboriginal Peoples Survey.

    Science.gov (United States)

    Ryan, Christopher; Leatherdale, Scott; Cooke, Martin

    2017-04-01

    First Nations and Métis, two of Canada's constitutionally recognized Indigenous groups, suffer from poorer overall health than non-Indigenous Canadians. Current smoking, a known predictor of chronic health conditions, is close to twice as prevalent among Indigenous youth as it is among non-Indigenous Canadian youth. However, little population-level research has examined the correlates of current smoking among this population. Guided by a health framework centered on Indigenous-specific determinants, we used data from the 2012 Aboriginal Peoples Survey to examine the correlates of current smoking among First Nations and Métis youth aged 15-17 years living outside of First Nations reserves. Using binary logistic regression, we investigated how culturally specific factors, namely knowledge of an Indigenous language, participation in traditional activities, and family members' attendance at residential schools, were correlated with current smoking. We also considered demographic, geographic, socioeconomic and health-related correlates. Overall, an estimated 20.6% of First Nations and Métis youth reported current smoking. We found no significant associations between culturally specific activities and current smoking in the multivariate analyses, although those who spoke an Indigenous language were more likely to smoke. Those who participated in sports more often were less likely to smoke, and respondents who reported heavy drinking and who were from families with lower income were more likely to smoke. Gender, body mass index, urban/rural geography and regional geography, and mother's highest level of education were not significantly correlated with smoking. The results of our study support prior research that has found a disturbingly high prevalence of current smoking among Indigenous youth, compared to their non-Indigenous counterparts. Our results highlight the importance of considering sports participation, co-occurring health-risk behaviours and socioeconomic

  17. Disease Severity in Never Smokers, Ex-Smokers, and Current Smokers With Axial Spondyloarthritis: Results From the Scotland Registry for Ankylosing Spondylitis.

    Science.gov (United States)

    Jones, Gareth T; Ratz, Tiara; Dean, Linda E; Macfarlane, Gary J; Atzeni, Fabiola

    2017-09-01

    To examine the relationship between smoking, smoking cessation, and disease characteristics and quality of life (QoL) in spondyloarthritis. The Scotland Registry for Ankylosing Spondylitis collects data from clinically diagnosed patients with spondyloarthritis. Clinical data, including Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) and the Bath Ankylosing Spondylitis Functional Index (BASFI) scores, were obtained from medical records. Mailed questionnaires contained information on smoking status and QoL (Ankylosing Spondylitis QoL questionnaire [ASQoL]). Linear and logistic regression were used to quantify the effect of smoking, and smoking cessation, on various disease-specific and QoL outcomes, with adjustments for age, sex, deprivation, education level, and alcohol use. Results are presented as regression coefficients (β) or odds ratios (ORs) with 95% confidence intervals (95% CIs). Data were obtained from 946 participants (73.5% male, mean age 52 years). Current smoking was reported by 22%, and 38% were ex-smokers. Ever smokers had poorer BASDAI (β = 0.5 [95% CI 0.2, 0.9]) and BASFI scores (β = 0.8 [95% CI 0.4, 1.2]), and reported worse QoL (ASQoL β = 1.5 [95% CI 0.7, 2.3]). Compared to current smokers, ex-smokers reported less disease activity (BASDAI β = -0.5 [95% CI -1.0, -0.04]) and significantly better QoL (ASQoL β = -1.2 [95% CI -2.3, -0.2]). They also were more likely to have a history of uveitis (OR 2.4 [95% CI 1.5, 3.8]). Smokers with spondyloarthritis experience worse disease than those who are never smokers. However, this study provides new evidence that, among smokers, smoking cessation is associated with lower disease activity and better physical function and QoL. Clinicians should specifically promote smoking cessation as an adjunct to usual therapy in patients with spondyloarthritis. © 2016, American College of Rheumatology.

  18. Bedrock geologic map of the Spring Valley, West Plains, and parts of the Piedmont and Poplar Bluff 30'x60' quadrangles, Missouri, including the upper Current River and Eleven Point River drainage basins

    Science.gov (United States)

    Weary, David J.; Harrison, Richard W.; Orndorff, Randall C.; Weems, Robert E.; Schindler, J. Stephen; Repetski, John E.; Pierce, Herbert A.

    2015-01-01

    This map covers the drainage basins of the upper Current River and the Eleven Point River in the Ozark Plateaus physiographic province of southeastern Missouri. The two surface drainage basins are contiguous in their headwaters regions, but are separated in their lower reaches by the lower Black River basin in the southeast corner of the map area. Numerous dye-trace studies demonstrate that in the contiguous headwaters areas, groundwater flows from the Eleven Point River basin into the Current River basin. Much of the groundwater discharge of the Eleven Point River basin emanates from Big Spring, located on the Current River. This geologic map and cross sections were produced to help fulfill a need to understand the geologic framework of the region in which this subsurface flow occurs.

  19. Initial results on the correlation between the magnetic and electric fields observed from the DE-2 satellite in the field-aligned current regions

    Science.gov (United States)

    Sugiura, M.; Maynard, N. C.; Farthing, W. H.; Heppner, J. P.; Ledley, B. G.; Cahill, L. J., Jr.

    1982-01-01

    Initial results of the electric and magnetic field observations from the DE-2 satellite show a remarkably good correlation between the north-south component of the electric field and the east-west component of the magnetic field in many passes of the field-aligned current regions. For a dayside cusp pass on August 15, 1981 the coefficient of correlation between these components was 0.996. A preliminary inspection of the available data from the first 6 months of the DE operation indicates that the similarity between the electric and magnetic field signatures of the field-aligned currents is a commonly observed feature at all local times. This high correlation is interpreted to be an indication that the closure of the field-aligned current is essentially meridional. When the correlation between these components is not good, the closure current is likely to be flowing along the auroral belt. When the correlation between the electric and magnetic fields is high, it is possible to estimate the height-integrated Pedersen conductivity from the observed field components.

  20. Families classification including multiopposition asteroids

    Science.gov (United States)

    Milani, Andrea; Spoto, Federica; Knežević, Zoran; Novaković, Bojan; Tsirvoulis, Georgios

    2016-01-01

    In this paper we present the results of our new classification of asteroid families, upgraded by using catalog with > 500,000 asteroids. We discuss the outcome of the most recent update of the family list and of their membership. We found enough evidence to perform 9 mergers of the previously independent families. By introducing an improved method of estimation of the expected family growth in the less populous regions (e.g. at high inclination) we were able to reliably decide on rejection of one tiny group as a probable statistical fluke. Thus we reduced our current list to 115 families. We also present newly determined ages for 6 families, including complex 135 and 221, improving also our understanding of the dynamical vs. collisional families relationship. We conclude with some recommendations for the future work and for the family name problem.

  1. Comparison of the Effect of Vaginal Zataria multiflora Cream and Oral Metronidazole Pill on Results of Treatments for Vaginal Infections including Trichomoniasis and Bacterial Vaginosis in Women of Reproductive Age

    Directory of Open Access Journals (Sweden)

    Khadijeh Abdali

    2015-01-01

    Full Text Available Effect of Zataria multiflora on bacterial vaginosis and Trichomonas vaginalis is shown in vivo and in vitro. We compare the effectiveness of Zataria multiflora cream and oral metronidazole pill on results of treatment for vaginal infections including Trichomonas and bacterial vaginosis; these infections occur simultaneously. The study included 420 women with bacterial vaginosis, Trichomonas vaginalis, or both infections together, who were randomly divided into six groups. Criteria for diagnosis were wet smear and Gram stain. Vaginal Zataria multiflora cream and placebo pill were administered to the experiment groups; the control group received oral metronidazole pill and vaginal placebo cream. Comparison of the clinical symptoms showed no significant difference in all three vaginitis groups receiving metronidazole pill and vaginal Zataria multiflora cream. However, comparison of the wet smear test results was significant in patients with trichomoniasis and bacterial vaginosis associated with trichomoniasis in the two treatment groups (p=0.001 and p=0.01. Vaginal Zataria multiflora cream had the same effect of oral metronidazole tablets in improving clinical symptoms of all three vaginitis groups, as well as the treatment for bacterial vaginosis. It can be used as a drug for treatment of bacterial vaginosis and elimination of clinical symptoms of Trichomonas vaginitis.

  2. Comparison of the Effect of Vaginal Zataria multiflora Cream and Oral Metronidazole Pill on Results of Treatments for Vaginal Infections including Trichomoniasis and Bacterial Vaginosis in Women of Reproductive Age

    Science.gov (United States)

    Abdali, Khadijeh; Jahed, Leila; Amooee, Sedigheh; Zarshenas, Mahnaz; Tabatabaee, Hamidreza; Bekhradi, Reza

    2015-01-01

    Effect of Zataria multiflora on bacterial vaginosis and Trichomonas vaginalis is shown in vivo and in vitro. We compare the effectiveness of Zataria multiflora cream and oral metronidazole pill on results of treatment for vaginal infections including Trichomonas and bacterial vaginosis; these infections occur simultaneously. The study included 420 women with bacterial vaginosis, Trichomonas vaginalis, or both infections together, who were randomly divided into six groups. Criteria for diagnosis were wet smear and Gram stain. Vaginal Zataria multiflora cream and placebo pill were administered to the experiment groups; the control group received oral metronidazole pill and vaginal placebo cream. Comparison of the clinical symptoms showed no significant difference in all three vaginitis groups receiving metronidazole pill and vaginal Zataria multiflora cream. However, comparison of the wet smear test results was significant in patients with trichomoniasis and bacterial vaginosis associated with trichomoniasis in the two treatment groups (p = 0.001 and p = 0.01). Vaginal Zataria multiflora cream had the same effect of oral metronidazole tablets in improving clinical symptoms of all three vaginitis groups, as well as the treatment for bacterial vaginosis. It can be used as a drug for treatment of bacterial vaginosis and elimination of clinical symptoms of Trichomonas vaginitis. PMID:26266260

  3. Comparison of the Effect of Vaginal Zataria multiflora Cream and Oral Metronidazole Pill on Results of Treatments for Vaginal Infections including Trichomoniasis and Bacterial Vaginosis in Women of Reproductive Age.

    Science.gov (United States)

    Abdali, Khadijeh; Jahed, Leila; Amooee, Sedigheh; Zarshenas, Mahnaz; Tabatabaee, Hamidreza; Bekhradi, Reza

    2015-01-01

    Effect of Zataria multiflora on bacterial vaginosis and Trichomonas vaginalis is shown in vivo and in vitro. We compare the effectiveness of Zataria multiflora cream and oral metronidazole pill on results of treatment for vaginal infections including Trichomonas and bacterial vaginosis; these infections occur simultaneously. The study included 420 women with bacterial vaginosis, Trichomonas vaginalis, or both infections together, who were randomly divided into six groups. Criteria for diagnosis were wet smear and Gram stain. Vaginal Zataria multiflora cream and placebo pill were administered to the experiment groups; the control group received oral metronidazole pill and vaginal placebo cream. Comparison of the clinical symptoms showed no significant difference in all three vaginitis groups receiving metronidazole pill and vaginal Zataria multiflora cream. However, comparison of the wet smear test results was significant in patients with trichomoniasis and bacterial vaginosis associated with trichomoniasis in the two treatment groups (p = 0.001 and p = 0.01). Vaginal Zataria multiflora cream had the same effect of oral metronidazole tablets in improving clinical symptoms of all three vaginitis groups, as well as the treatment for bacterial vaginosis. It can be used as a drug for treatment of bacterial vaginosis and elimination of clinical symptoms of Trichomonas vaginitis.

  4. DNA commission of the International Society of Forensic Genetics: Recommendations on the evaluation of STR typing results that may include drop-out and/or drop-in using probabilistic methods

    Science.gov (United States)

    Gill, P.; Gusmão, L.; Haned, H.; Mayr, W.R.; Morling, N.; Parson, W.; Prieto, L.; Prinz, M.; Schneider, H.; Schneider, P.M.; Weir, B.S.

    2015-01-01

    DNA profiling of biological material from scenes of crimes is often complicated because the amount of DNA is limited and the quality of the DNA may be compromised. Furthermore, the sensitivity of STR typing kits has been continuously improved to detect low level DNA traces. This may lead to (1) partial DNA profiles and (2) detection of additional alleles. There are two key phenomena to consider: allelic or locus ‘drop-out’, i.e. ‘missing’ alleles at one or more genetic loci, while ‘drop-in’ may explain alleles in the DNA profile that are additional to the assumed main contributor(s). The drop-in phenomenon is restricted to 1 or 2 alleles per profile. If multiple alleles are observed at more than two loci then these are considered as alleles from an extra contributor and analysis can proceed as a mixture of two or more contributors. Here, we give recommendations on how to estimate probabilities considering drop-out, Pr(D), and drop-in, Pr(C). For reasons of clarity, we have deliberately restricted the current recommendations considering drop-out and/or drop-in at only one locus. Furthermore, we offer recommendations on how to use Pr(D) and Pr(C) with the likelihood ratio principles that are generally recommended by the International Society of Forensic Genetics (ISFG) as measure of the weight of the evidence in forensic genetics. Examples of calculations are included. An Excel spreadsheet is provided so that scientists and laboratories may explore the models and input their own data. PMID:22864188

  5. DNA commission of the International Society of Forensic Genetics: Recommendations on the evaluation of STR typing results that may include drop-out and/or drop-in using probabilistic methods.

    Science.gov (United States)

    Gill, P; Gusmão, L; Haned, H; Mayr, W R; Morling, N; Parson, W; Prieto, L; Prinz, M; Schneider, H; Schneider, P M; Weir, B S

    2012-12-01

    DNA profiling of biological material from scenes of crimes is often complicated because the amount of DNA is limited and the quality of the DNA may be compromised. Furthermore, the sensitivity of STR typing kits has been continuously improved to detect low level DNA traces. This may lead to (1) partial DNA profiles and (2) detection of additional alleles. There are two key phenomena to consider: allelic or locus 'drop-out', i.e. 'missing' alleles at one or more genetic loci, while 'drop-in' may explain alleles in the DNA profile that are additional to the assumed main contributor(s). The drop-in phenomenon is restricted to 1 or 2 alleles per profile. If multiple alleles are observed at more than two loci then these are considered as alleles from an extra contributor and analysis can proceed as a mixture of two or more contributors. Here, we give recommendations on how to estimate probabilities considering drop-out, Pr(D), and drop-in, Pr(C). For reasons of clarity, we have deliberately restricted the current recommendations considering drop-out and/or drop-in at only one locus. Furthermore, we offer recommendations on how to use Pr(D) and Pr(C) with the likelihood ratio principles that are generally recommended by the International Society of Forensic Genetics (ISFG) as measure of the weight of the evidence in forensic genetics. Examples of calculations are included. An Excel spreadsheet is provided so that scientists and laboratories may explore the models and input their own data. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  6. In-vessel Retention Strategy for High Power Reactors - K-INERI Final Report (includes SBLB Test Results for Task 3 on External Reactor Vessel Cooling (ERVC) Boiling Data and CHF Enhancement Correlations)

    Energy Technology Data Exchange (ETDEWEB)

    F. B. Cheung; J. Yang; M. B. Dizon; J. Rempe

    2005-01-01

    In-vessel retention (IVR) of core melt is a key severe accident management strategy adopted by some operating nuclear power plants and proposed for some advanced light water reactors (ALWRs). If there were inadequate cooling during a reactor accident, a significant amount of core material could become molten and relocate to the lower head of the reactor vessel, as happened in the Three Mile Island Unit 2 (TMI-2) accident. If it is possible to ensure that the vessel head remains intact so that relocated core materials are retained within the vessel, the enhanced safety associated with these plants can reduce concerns about containment failure and associated risk. For example, the enhanced safety of the Westinghouse Advanced 600 MWe PWR (AP600), which relied upon External Reactor Vessel Cooling (ERVC) for IVR, resulted in the U.S. Nuclear Regulatory Commission (US NRC) approving the design without requiring certain conventional features common to existing LWRs. However, it is not clear that currently proposed external reactor vessel cooling (ERVC) without additional enhancements could provide sufficient heat removal for higher-power reactors (up to 1500 MWe). Hence, a collaborative, three-year, U.S. - Korean International Nuclear Energy Research Initiative (INERI) project was completed in which the Idaho National Engineering and Environmental Laboratory (INEEL), Seoul National University (SNU), Pennsylvania State University (PSU), and the Korea Atomic Energy Research Institute (KAERI) investigated the performance of ERVC and an in-vessel core catcher (IVCC) to determine if IVR is feasible for reactors up to 1500 MWe.

  7. Update of the BIPM comparison BIPM.RI(II)-K1.Sr-85 of activity measurements of the radionuclide 85Sr to include the 2009 result of the POLATOM (Poland)

    Science.gov (United States)

    Michotte, C.; Ratel, G.; Courte, S.; Dziel, T.; Listkowska, A.

    2015-01-01

    Since 1975, ten laboratories have submitted 27 samples of known activity of 85Sr to the International Reference System (SIR) for activity comparison at the Bureau International des Poids et Mesures (BIPM), with comparison identifier BIPM.RI(II)-K1.Sr-85. The values of the activity submitted were between about 0.2 MBq and 19 MBq. The key comparison reference value (KCRV) has been recalculated to include the primary standardization result for the POLATOM, Poland. There are now four results in the BIPM.RI(II)-K1.Sr-85 comparison. The degrees of equivalence between each equivalent activity measured in the SIR and the updated KCRV have been calculated and the results are given in the form of a table. A graphical presentation is also given. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCRI, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

  8. Application of the reciprocity theorem to EEG inversion and optimization of EEG-driven transcranial current stimulation (tCS, including tDCS, tACS, tRNS)

    CERN Document Server

    Ruffini, Giulio

    2015-01-01

    Multichannel transcranial current stimulation (tCS) systems offer the possibility of EEG-guided optimized, non-invasive brain stimulation. In this brief technical note I explain how it is possible to use tCS electric field realistic brain model to create a forward "lead-field" matrix and, from that, an EEG inverter for cortical mapping. Starting from EEG I show how to generate 2D cortical surface dipole fields that could produce the observed EEG electrode voltages. The main tool is the reciprocity theorem derived by Helmholtz. The application of reciprocity for the generation of a forward mapping matrix (lead field matrix as is sometimes known) is well known [Rush and Driscoll, 1969], but here we will use it in combination with the realistic head models of [Miranda et al 2013] to provide cortical mapping solutions compatible with realistic head model tCS optimization. I also provide a generalization of the reciprocity theorem [Helmholtz 1853] to the case of multiple electrode contact points and dipole sources...

  9. First field test of the theory of ignition and dissipation in sediment density currents - results from Squamish prodelta, British Columbia, Canada.

    Science.gov (United States)

    Hizzett, Jamie; Hughes Clarke, John; Cartigny, Matthieu; Talling, Peter; Clare, Michael; Sumner, Esther

    2016-04-01

    seafloor gradient falls below 3o; causing the flow to wane before reaching the lobe. Two of the three turbidity currents analysed ignite thus supporting the 'ignition-dissipation' hypothesis. The present analysis shows that ignition is not related to the flow trigger and that relatively large failures do not necessarily result in long run out flows. Perhaps it is the case that the largest dissipative flows lead to the largest ignitive flows, resulting from a greater supply of unconsolidated sediment for the ignition process. Completion of the analysis of the remaining 133 flows in this dataset will enable a more thorough test of the 'ignition-dissipation' hypothesis.

  10. Current Issues Affecting the Practice of Pediatric Orthopaedic Surgeons: Results of the 2014 Workforce Survey of American Academy of Pediatrics Section on Orthopaedics.

    Science.gov (United States)

    Hosseinzadeh, Pooya; Copley, Lawson; Ruch-Ross, Holly; Schwend, Richard M; Sawyer, Jeffrey R

    2016-09-22

    The opinions of the pediatric orthopaedic workforce are shaped by market forces, regulatory processes, and local experience. The purpose of this report is to summarize the findings of the recent Workforce Survey of the American Academy of Pediatrics (AAP) Section on Orthopaedics (SOOr). This submission has been reviewed and approved by the Board of Directors of the Pediatric Orthopaedic Society of North America (POSNA). In 2014, the AAP generated a survey to assess perceptions of pediatric orthopaedic surgeons about current issues that affect practice. The survey was sent to 856 POSNA and 141 AAP-SOOr members. Responses were topically organized to report current workforce composition, practice patterns, and perceptions about electronic medical records (EMRs). Responses were collected from August to December, 2014, from 496 (50%) survey recipients including 83 of 141 (59%) AAP-SOOr members and 413 of 856 (48%) POSNA members. Analyses were restricted to the 397 respondents who reported that they are currently practicing pediatric orthopaedics. Nearly all of these (390/391, 100%) indicated that they provide direct patient care and work an average of 60 hours per week. Many (105/378, 28%) indicated that they would soon limit their practice or retire. A majority (299/394, 76%) indicated that they face competition in their geographic area, predominantly due to pediatric orthopaedic subspecialists (269/299, 90%). Major business changes had recently occurred or were anticipated by 21% of participants. Respondents reported that use of EMR makes them less efficient (252/397, 63%) and interferes with the patient-physician relationship (172/397, 43%). This workforce survey suggests that pediatric orthopaedic surgeons are concerned with challenges of competition despite concurrent increasing volume and complexity of referrals. External processes such as EMR changes are perceived to negatively impact practice efficiency and satisfaction.

  11. A review of the currently recognised zoogonid cercariae, including the identification and emergence ecology of Cercaria capricornia XI (Digenea: Zoogonidae) from Nassarius olivaceus (Gastropoda: Nassariidae) in Central Queensland, Australia.

    Science.gov (United States)

    Barnett, Leonie J; Miller, Terrence L; Cribb, Thomas H

    2014-08-01

    In the present study, we review the known zoogonid cercariae, summarise their life-cycles and first intermediate host distributions, and present a new cercaria, Cercaria capricornia XI (Digenea: Zoogonidae), which was found in one of three nassariid gastropods, Nassarius olivaceus (Bruguière), surveyed in the intertidal zone in the Capricornia region of Central Queensland, Australia. Morphological data and molecular analysis of the ITS2 rDNA region support placement of this cercaria in the family Zoogonidae but do not allow any further resolution of its identity. There are now fifteen cercariae described as belonging to the Zoogonidae; thirteen of these, including the present species, infect neogastropods as first intermediate hosts and two use vetigastropods. This study reinforces the pattern that the Nassariidae is by far the most commonly reported family for the Zoogonidae. Given its richness we predict that the Nassariidae will prove to harbour many more zoogonid species.

  12. KEY COMPARISON Update of the BIPM.RI(II)-K1.Tc-99m comparison of activity measurements for the radionuclide 99mTc to include new results for the LNE-LNHB and the NPL

    Science.gov (United States)

    Michotte, C.; Courte, S.; Ratel, G.; Moune, M.; Johansson, L.; Keightley, J.

    2010-01-01

    In 2007 and 2008 respectively, the Laboratoire national de métrologie et d'essais-Laboratoire national Henri Becquerel (LNE-LNHB), France and the National Physical Laboratory (NPL), UK, submitted ampoules with between 10 MBq and 130 MBq activity of 99mTc to the International Reference System (SIR), to update their results in the BIPM.RI(II)-K1.Tc-99m comparison. Together with the four other national metrology institutes (NMI) that are participants, thirteen samples have been submitted since 1983. The key comparison reference value (KCRV) has been recalculated to include the latest primary results of the PTB and the LNE-LNHB as this makes the evaluation more robust. The degrees of equivalence between each equivalent activity measured in the SIR are given in the form of a matrix for all six NMIs. A graphical presentation is also given. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCRI Section II, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).

  13. Final NOMAD results on {nu}{sub {mu}}{yields}{nu}{sub {tau}} and {nu}{sub e}{yields}{nu}{sub {tau}} oscillations including a new search for {nu}{sub {tau}} appearance using hadronic {tau} decays

    Energy Technology Data Exchange (ETDEWEB)

    Astier, P.; Autiero, D.; Baldisseri, A.; Baldo-Ceolin, M.; Banner, M.; Bassompierre, G.; Benslama, K.; Besson, N.; Bird, I.; Blumenfeld, B.; Bobisut, F.; Bouchez, J.; Boyd, S.; Bueno, A.; Bunyatov, S.; Camilleri, L.; Cardini, A.; Cattaneo, P.W.; Cavasinni, V.; Cervera-Villanueva, A.; Chukanov, A.; Collazuol, G.; Conforto, G.; Conta, C.; Contalbrigo, M.; Cousins, R.; Daniels, D.; Degaudenzi, H.; Del Prete, T.; De Santo, A.; Dignan, T.; Di Lella, L.; Couto e Silva, E. do; Dumarchez, J.; Ellis, M.; Feldman, G.J.; Ferrari, R.; Ferrere, D.; Flaminio, V.; Fraternali, M.; Gaillard, J.-M.; Gangler, E.; Geiser, A.; Geppert, D.; Gibin, D.; Gninenko, S.; Godley, A.; Gomez-Cadenas, J.-J.; Gosset, J.; Goessling, C.; Gouanere, M.; Grant, A.; Graziani, G.; Guglielmi, A.; Hagner, C.; Hernando, J.; Hubbard, D.; Hurst, P.; Hyett, N.; Iacopini, E.; Joseph, C.; Juget, F.; Kirsanov, M.; Klimov, O.; Kokkonen, J.; Kovzelev, A.; Krasnoperov, A.; Kustov, D.; Kuznetsov, V.E.; Lacaprara, S.; Lachaud, C.; Lakic, B.; Lanza, A.; La Rotonda, L.; Laveder, M.; Letessier-Selvon, A.; Levy, J.-M.; Linssen, L.; Ljubic, A.; Long, J.; Lupi, A.; Marchionni, A.; Martelli, F.; Mechain, X.; Mendiburu, J.-P.; Meyer, J.-P.; Mezzetto, M.; Mishra, S.R.; Moorhead, G.F.; Naumov, D.; Nedelec, P.; Nefedov, Yu.; Nguyen-Mau, C.; Orestano, D.; Pastore, F.; Peak, L.S.; Pennacchio, E.; Pessard, H.; Petti, R. E-mail: roberto.petti@cern.ch; Placci, A.; Polesello, G.; Pollmann, D.; Polyarush, A.; Popov, B.; Poulsen, C.; Rico, J.; Riemann, P.; Roda, C.; Rubbia, A.; Salvatore, F.; Schahmaneche, K.; Schmidt, B.; Schmidt, T.; Sconza, A.; Sevior, M.; Sillou, D.; Soler, F.J.P.; Sozzi, G.; Steele, D.; Stiegler, U.; Stipc, M.; Stolarczyk, Th.; Tareb-Reyes, M.; Taylor, G.N.; Tereshchenko, V.; Toropin, A.; Touchard, A.-M.; Tovey, S.N.; Tran, M.-T.; Tsesmelis, E.; Ulrichs, J.; Vacavant, L.; Valdata-Nappi, M.; Valuev, V.; Vannucci, F.; Varvell, K.E.; Veltri, M.; Vercesi, V.; Vidal-Sitjes, G.; Vieira, J.-M.; Vinogradova, T.[and others

    2001-09-17

    Results from the {nu}{sub {tau}} appearance search in a neutrino beam using the full NOMAD data sample are reported. A new analysis unifies all the hadronic {tau} decays, significantly improving the overall sensitivity of the experiment to oscillations. The 'blind analysis' of all topologies yields no evidence for an oscillation signal. In the two-family oscillation scenario, this sets a 90% CL allowed region in the sin{sup 2}2{theta}{sub {mu}}{sub {tau}}-{delta}m{sup 2} plane which includes sin{sup 2}2{theta}{sub {mu}}{sub {tau}}<3.3x10{sup -4} at large {delta}m{sup 2} and {delta}m{sup 2}< 0.7 eV{sup 2}/c{sup 4} at sin{sup 2}2{theta}{sub {mu}}{sub {tau}}=1. The corresponding contour in the {nu}{sub e}{yields}{nu}{sub {tau}} oscillation hypothesis results in sin{sup 2}2{theta}{sub e{tau}}<1.5x10{sup -2} at large {delta}m{sup 2} and {delta}m{sup 2}<5.9 eV{sup 2}/c{sup 4} at sin{sup 2}2{theta}{sub e{tau}}=1. We also derive limits on effective couplings of the {tau} lepton to {nu}{sub {mu}} or {nu}{sub e}.

  14. Final NOMAD results on νμ→ ντ and νe→ ντ oscillations including a new search for ντ appearance using hadronic τ decays

    Science.gov (United States)

    Astier, P.; Autiero, D.; Baldisseri, A.; Baldo-Ceolin, M.; Banner, M.; Bassompierre, G.; Benslama, K.; Besson, N.; Bird, I.; Blumenfeld, B.; Bobisut, F.; Bouchez, J.; Boyd, S.; Bueno, A.; Bunyatov, S.; Camilleri, L.; Cardini, A.; Cattaneo, P. W.; Cavasinni, V.; Cervera-Villanueva, A.; Chukanov, A.; Collazuol, G.; Conforto, G.; Conta, C.; Contalbrigo, M.; Cousins, R.; Daniels, D.; Degaudenzi, H.; Del Prete, T.; de Santo, A.; Dignan, T.; di Lella, L.; Do Couto E Silva, E.; Dumarchez, J.; Ellis, M.; Feldman, G. J.; Ferrari, R.; Ferrère, D.; Flaminio, V.; Fraternali, M.; Gaillard, J.-M.; Gangler, E.; Geiser, A.; Geppert, D.; Gibin, D.; Gninenko, S.; Godley, A.; Gomez-Cadenas, J.-J.; Gosset, J.; Gößling, C.; Gouanère, M.; Grant, A.; Graziani, G.; Guglielmi, A.; Hagner, C.; Hernando, J.; Hubbard, D.; Hurst, P.; Hyett, N.; Iacopini, E.; Joseph, C.; Juget, F.; Kirsanov, M.; Klimov, O.; Kokkonen, J.; Kovzelev, A.; Krasnoperov, A.; Kustov, D.; Kuznetsov, V. E.; Lacaprara, S.; Lachaud, C.; Lakić, B.; Lanza, A.; La Rotonda, L.; Laveder, M.; Letessier-Selvon, A.; Levy, J.-M.; Linssen, L.; Ljubič, A.; Long, J.; Lupi, A.; Marchionni, A.; Martelli, F.; Méchain, X.; Mendiburu, J.-P.; Meyer, J.-P.; Mezzetto, M.; Mishra, S. R.; Moorhead, G. F.; Naumov, D.; Nédélec, P.; Nefedov, Yu; Nguyen-Mau, C.; Orestano, D.; Pastore, F.; Peak, L. S.; Pennacchio, E.; Pessard, H.; Petti, R.; Placci, A.; Polesello, G.; Pollmann, D.; Polyarush, A.; Popov, B.; Poulsen, C.; Rico, J.; Riemann, P.; Roda, C.; Rubbia, A.; Salvatore, F.; Schahmaneche, K.; Schmidt, B.; Schmidt, T.; Sconza, A.; Sevior, M.; Sillou, D.; Soler, F. J. P.; Sozzi, G.; Steele, D.; Stiegler, U.; Stipč, M.; Stolarczyk, Th; Tareb-Reyes, M.; Taylor, G. N.; Tereshchenko, V.; Toropin, A.; Touchard, A.-M.; Tovey, S. N.; Tran, M.-T.; Tsesmelis, E.; Ulrichs, J.; Vacavant, L.; Valdata-Nappi, M.; Valuev, V.; Vannucci, F.; Varvell, K. E.; Veltri, M.; Vercesi, V.; Vidal-Sitjes, G.; Vieira, J.-M.; Vinogradova, T.; Weber, F. V.; Weisse, T.; Wilson, F. F.; Winton, L. J.; Yabsley, B. D.; Zaccone, H.; Zuber, K.; Zuccon, P.; NOMAD Collaboration

    2001-09-01

    Results from the ντ appearance search in a neutrino beam using the full NOMAD data sample are reported. A new analysis unifies all the hadronic τ decays, significantly improving the overall sensitivity of the experiment to oscillations. The "blind analysis" of all topologies yields no evidence for an oscillation signal. In the two-family oscillation scenario, this sets a 90% CL allowed region in the sin 22 θμτ- Δm2 plane which includes sin 22 θμτ<3.3×10 -4 at large Δm2 and Δm2< 0.7 eV 2/ c4 at sin 22 θμτ=1. The corresponding contour in the νe→ ντ oscillation hypothesis results in sin 22 θeτ<1.5×10 -2 at large Δm2 and Δm2<5.9 eV 2/ c4 at sin 22 θeτ=1. We also derive limits on effective couplings of the τ lepton to νμ or νe.

  15. Prevalence, Recurrence, and Incidence of Current Depressive Symptoms among People Living with HIV in Ontario, Canada: Results from the Ontario HIV Treatment Network Cohort Study

    Science.gov (United States)

    Choi, Stephanie K. Y.; Boyle, Eleanor; Cairney, John; Collins, Evan J.; Gardner, Sandra; Bacon, Jean; Rourke, Sean B.

    2016-01-01

    Introduction Current studies of depression among people living with HIV focus on describing its point prevalence. Given the fluctuating nature of depression and its profound impacts on clinical and quality-of-life outcomes, this study aimed to examine the prevalence, recurrence and incidence of current depressive symptoms and its underlying catalysts longitudinally and systematically among these individuals. Methods We conducted a prospective cohort study between October 1, 2007 and December 31, 2012 using longitudinal linked data sources. Current depressive symptoms was identified using the Centre for Epidemiologic Studies Depression Scale or the Kessler Psychological Distress Scale, first at baseline and again during follow-up interviews. Multivariable regressions were used to characterize the three outcomes. Results Of the 3,816 HIV-positive participants, the point prevalence of depressive symptoms was estimated at 28%. Of the 957 participants who were identified with depressive symptoms at baseline and who had at least two years of follow-up, 43% had a recurrent episode. The cumulative incidence among 1,745 previously depressive symptoms free participants (at or prior to baseline) was 14%. During the five-year follow-up, our multivariable models showed that participants with greater risk of recurrent cases were more likely to feel worried about their housing situation. Participants at risk of developing incident cases were also likely to be younger, gay or bisexual, and unable to afford housing-related expenses. Conclusions Depressive symptoms are prevalent and likely to recur among people living with HIV. Our results support the direction of Ontario’s HIV/AIDS Strategy to 2026, which addresses medical concerns associated with HIV (such as depression) and the social drivers of health in order to enhance the overall well-being of people living with or at risk of HIV. Our findings reinforce the importance of providing effective mental health care and

  16. Ionic size effects to molecular solvation energy and to ion current across a channel resulted from the nonuniform size-modified PNP equations.

    Science.gov (United States)

    Qiao, Yu; Tu, Bin; Lu, Benzhuo

    2014-05-07

    Ionic finite size can impose considerable effects to both the equilibrium and non-equilibrium properties of a solvated molecular system, such as the solvation energy, ionic concentration, and transport in a channel. As discussed in our former work [B. Lu and Y. C. Zhou, Biophys. J. 100, 2475 (2011)], a class of size-modified Poisson-Boltzmann (PB)/Poisson-Nernst-Planck (PNP) models can be uniformly studied through the general nonuniform size-modified PNP (SMPNP) equations deduced from the extended free energy functional of Borukhov et al. [I. Borukhov, D. Andelman, and H. Orland, Phys. Rev. Lett. 79, 435 (1997)] This work focuses on the nonuniform size effects to molecular solvation energy and to ion current across a channel for real biomolecular systems. The main contributions are: (1) we prove that for solvation energy calculation with nonuniform size effects (through equilibrium SMPNP simulation), there exists a simplified approximation formulation which is the same as the widely used one in PB community. This approximate form avoids integration over the whole domain and makes energy calculations convenient. (2) Numerical calculations show that ionic size effects tend to negate the solvation effects, which indicates that a higher molecular solvation energy (lower absolute value) is to be predicted when ionic size effects are considered. For both calculations on a protein and a DNA fragment systems in a 0.5M 1:1 ionic solution, a difference about 10 kcal/mol in solvation energies is found between the PB and the SMPNP predictions. Moreover, it is observed that the solvation energy decreases as ionic strength increases, which behavior is similar as those predicted by the traditional PB equation (without size effect) and by the uniform size-modified Poisson-Boltzmann equation. (3) Nonequilibrium SMPNP simulations of ion permeation through a gramicidin A channel show that the ionic size effects lead to reduced ion current inside the channel compared with the results

  17. Identification of steel bars immersed in reinforced concrete based on experimental results of eddy current testing and artificial neural network analysis

    Science.gov (United States)

    de Alcantara, Naasson

    2013-03-01

    This paper presents an experimental research on the use of eddy current testing (ECT) and artificial neural networks (ANNs) in order to identify the gauge and position of steel bars immersed in concrete structures. The paper presents details of the ECT probe and concrete specimens constructed for the tests, and a study about the influence of the concrete on the values of measured voltages. After this, new measurements were done with a greater number of specimens, simulating a field condition and the results were used to generate training and validation vectors for multilayer perceptron ANNs. The results show a high percentage of correct identification with respect to both, the gauge of the bar and of the thickness of the concrete cover.

  18. Efficacy of certolizumab pegol on signs and symptoms of axial spondyloarthritis including ankylosing spondylitis: 24-week results of a double-blind randomised placebo-controlled Phase 3 study

    Science.gov (United States)

    Landewé, R; Braun, J; Deodhar, A; Dougados, M; Maksymowych, W P; Mease, P J; Reveille, J D; Rudwaleit, M; van der Heijde, D; Stach, C; Hoepken, B; Fichtner, A; Coteur, G; de Longueville, M; Sieper, J

    2014-01-01

    Objectives To evaluate the efficacy and safety of certolizumab pegol (CZP) after 24 weeks in RAPID-axSpA (NCT01087762), an ongoing Phase 3 trial in patients with axial spondyloarthritis (axSpA), including patients with ankylosing spondylitis (AS) and non-radiographic axSpA (nr-axSpA). Methods Patients with active axSpA were randomised 1:1:1 to placebo, CZP 200 mg every 2 weeks (Q2W) or CZP 400 mg every 4 weeks (Q4W). In total 325 patients were randomised. Primary endpoint was ASAS20 (Assessment of SpondyloArthritis international Society 20) response at week 12. Secondary outcomes included change from baseline in Bath Ankylosing Spondylitis Functional Index (BASFI), Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), and Bath Ankylosing Spondylitis Metrology Index (BASMI) linear. Results Baseline disease activity was similar between AS and nr-axSpA. At week 12, ASAS20 response rates were significantly higher in CZP 200 mg Q2W and CZP 400 mg Q4W arms versus placebo (57.7 and 63.6 vs 38.3, p≤0.004). At week 24, combined CZP arms showed significant (p<0.001) differences in change from baseline versus placebo in BASFI (−2.28 vs −0.40), BASDAI (−3.05 vs −1.05), and BASMI (−0.52 vs −0.07). Improvements were observed as early as week 1. Similar improvements were reported with CZP versus placebo in both AS and nr-axSpA subpopulations. Adverse events were reported in 70.4% vs 62.6%, and serious adverse events in 4.7% vs 4.7% of All CZP versus placebo groups. No deaths or malignancies were reported. Conclusions CZP rapidly reduced the signs and symptoms of axSpA, with no new safety signals observed compared to the safety profile of CZP in RA. Similar improvements were observed across CZP dosing regimens, and in AS and nr-axSpA patients. PMID:24013647

  19. [Current controversies in glycemic control targets. What do the results of the latest clinical trials tell us about the approach to type 2 diabetes mellitus?].

    Science.gov (United States)

    Mauricio, Dídac; Rius, Ferran

    2010-09-01

    The aim of this article is to discuss the implications of the results obtained in the latest large-scale clinical trials designed to evaluate the effect of intensive glycemic control on the vascular complications associated with type 2 diabetes mellitus. The current scientific evidence is reviewed and the implications of the ACCORD (The Action to Control Cardiovascular Risk in Diabetes study group), ADVANCE (Action in Diabetes and Vascular disease: Preterax and Diamicron Modified Release Control Evaluation) and VADT (Veterans Affairs Diabetes Trial) clinical trials are discussed. General concerns of the studies and their implications for clinical practice and the management of type 2 diabetes, as well as the questions which still need to be answered by future clinical research are discussed.

  20. Modeling and stabilization results for a charge or current-actuated active constrained layer (ACL) beam model with the electrostatic assumption

    Science.gov (United States)

    Özer, Ahmet Özkan

    2016-04-01

    An infinite dimensional model for a three-layer active constrained layer (ACL) beam model, consisting of a piezoelectric elastic layer at the top and an elastic host layer at the bottom constraining a viscoelastic layer in the middle, is obtained for clamped-free boundary conditions by using a thorough variational approach. The Rao-Nakra thin compliant layer approximation is adopted to model the sandwich structure, and the electrostatic approach (magnetic effects are ignored) is assumed for the piezoelectric layer. Instead of the voltage actuation of the piezoelectric layer, the piezoelectric layer is proposed to be activated by a charge (or current) source. We show that, the closed-loop system with all mechanical feedback is shown to be uniformly exponentially stable. Our result is the outcome of the compact perturbation argument and a unique continuation result for the spectral problem which relies on the multipliers method. Finally, the modeling methodology of the paper is generalized to the multilayer ACL beams, and the uniform exponential stabilizability result is established analogously.

  1. Optical modulator including grapene

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Ming; Yin, Xiaobo; Zhang, Xiang

    2016-06-07

    The present invention provides for a one or more layer graphene optical modulator. In a first exemplary embodiment the optical modulator includes an optical waveguide, a nanoscale oxide spacer adjacent to a working region of the waveguide, and a monolayer graphene sheet adjacent to the spacer. In a second exemplary embodiment, the optical modulator includes at least one pair of active media, where the pair includes an oxide spacer, a first monolayer graphene sheet adjacent to a first side of the spacer, and a second monolayer graphene sheet adjacent to a second side of the spacer, and at least one optical waveguide adjacent to the pair.

  2. Surface Currents. Southwest North Pacific Ocean Including the Philippine Islands.

    Science.gov (United States)

    1977-07-01

    020’ a * 0*" *20 2*’ 20 .042 220’ 2*’ 200’ 2*2 2202 *2 2002 *02 2002 22022200 S 202’ 220’ 0*2 2022 0*’ 022’ ~52 0*2 02 000 2 p~2 2002 a’ o2o ~ .0 02 02

  3. Visual Impairment, Including Blindness

    Science.gov (United States)

    ... Who Knows What? Survey Item Bank Search for: Visual Impairment, Including Blindness Links updated, April 2017 En ... doesn’t wear his glasses. Back to top Visual Impairments in Children Vision is one of our ...

  4. Update of the BIPM comparison BIPM.RI(II)-K1.Cs-134 of activity measurements of the radionuclide 134Cs to include the 2008 results of the BEV (Austria), the 2009 result of the IRA (Switzerland) and the 2010 results of the NMISA (South Africa)

    Science.gov (United States)

    Michotte, C.; Ratel, G.; Courte, S.; Maringer, F. J.; Caffari, Y.; van Wyngaardt, W. M.

    2013-01-01

    Since 2008, three national metrology institutes have submitted ampoules for the measurement of 134Cs in the International Reference System (SIR). The values of the activity submitted were between about 0.17 MBq and 2.3 MBq. The primary standardization result for the IRA, Switzerland, replaces their earlier result of 1978 but no change is proposed for the key comparison reference value at the present time. There are now 14 results in the BIPM.RI(II)-K1.Cs-134 comparison. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCRI, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

  5. Update of the BIPM comparison BIPM.RI(II)-K1.Co-60 of activity measurements of the radionuclide 60Co to include the 2011 result of the CNEA (Argentina), the 2012 results of the BARC (India) and the NRC (Canada), and the 2014 result of the NIM (China)

    Science.gov (United States)

    Michotte, C.; Ratel, G.; Courte, S.; Arenillas, P.; Balpardo, C.; Joseph, L.; Anuradha, R.; Kulkarni, D. B.; Galea, R.; Moore, K.; Stroak, A.; Zhang, Ming; Liang, Juncheng; Liu, Haoran

    2017-01-01

    Since 2010, four national metrology institutes (NMI) have each submitted a sample of known activity of 60Co to the International Reference System (SIR) for activity comparison at the Bureau International des Poids et Mesures (BIPM), with comparison identifier BIPM.RI(II)-K1.Co-60. The values of the activity submitted were between about 175 kBq and 1600 kBq. The primary standardization results for the CNEA, Argentina and the BARC, India replace their earlier result of 2003 and 2001, respectively. There are now seventeen results in the BIPM.RI(II)-K1.Co-60 comparison. The key comparison reference value (KCRV) has been updated using the power-moderated weighted mean. The degrees of equivalence between each equivalent activity measured in the SIR and the KCRV have been calculated and the results are given in the form of a table. A graphical presentation is also given. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCRI, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

  6. The current state of physical activity and exercise programs in German-speaking, Swiss psychiatric hospitals: results from a brief online survey

    Science.gov (United States)

    Brand, Serge; Colledge, Flora; Beeler, Nadja; Pühse, Uwe; Kalak, Nadeem; Sadeghi Bahmani, Dena; Mikoteit, Thorsten; Holsboer-Trachsler, Edith; Gerber, Markus

    2016-01-01

    Background Physical activity and exercise programs (PAEPs) are an important factor in increasing and maintaining physical and mental health. This holds particularly true for patients with psychiatric disorders undergoing treatment in a psychiatric hospital. To understand whether the benefits reported in the literature are mirrored in current treatment modalities, the aim of the present study was to assess the current state of PAEPs in psychiatric hospitals in the German-speaking part of Switzerland. Methods All psychiatric hospitals (N=55) in the German-speaking part of Switzerland were contacted in spring 2014. Staff responsible for PAEPs were asked to complete an online questionnaire covering questions related to PAEPs such as type, frequency, staff training, treatment rationale, importance of PAEPs within the treatment strategy, and possible avenues to increase PAEPs. Results Staff members of 48 different psychiatric hospitals completed the survey. Hospitals provided the following therapeutic treatments: relaxation techniques (100%), sports therapy (97%), activity-related psychotherapeutic interventions (95%), physiotherapy (85%), body therapies (59%), far-east techniques (57%), and hippotherapy (22%). Frequencies ranged from once/week to five times/week. Approximately 25% of patients participated in the PAEPs. Interventions were offered irrespective of psychiatric disorders. PAEP providers wanted and needed more vocational training. Conclusion All participating psychiatric hospitals offer a broad variety of PAEPs in their treatment curricula. However, the majority of inpatients do not participate in PAEPs. Furthermore, those who do participate cannot continue to do so following discharge. PAEP providers need specific extended vocational trainings and believe that the potential of PA should be improved. PMID:27350748

  7. Update of the BIPM comparison BIPM.RI(II)-K1.Cu-64 of activity measurements of the radionuclide 64Cu to include the 2009 results of the CMI-IIR (Czech Rep.) and the NPL (UK), the 2010 result of the LNE-LNHB (France) and the 2011 result of the ENEA-INMRI (Italy)

    Science.gov (United States)

    Michotte, C.; Ratel, G.; Courte, S.; Sochorovà, J.; Auerbach, P.; Keightley, J.; Johansson, L.; Bakhshandeiar, E.; Cassette, P.; Moune, M.; Capogni, M.; De Felice, P.

    2013-01-01

    Since 2009, four national metrology institutes (NMI) have submitted four samples of known activity of 64Cu to the International Reference System (SIR) for activity comparison at the Bureau International des Poids et Mesures (BIPM), with comparison identifier BIPM.RI(II)-K1.Cu-64. The values of the activity submitted were between about 3 MBq and 260 MBq. There are now five results in the BIPM.RI(II)-K1.Cu-64 comparison. A key comparison reference value (KCRV) has been calculated for the first time for this nuclide. The degrees of equivalence between each equivalent activity measured in the SIR and the KCRV have been calculated and the results are given in the form of a table. A graphical presentation is also given. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCRI, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

  8. Analytic device including nanostructures

    KAUST Repository

    Di Fabrizio, Enzo M.

    2015-07-02

    A device for detecting an analyte in a sample comprising: an array including a plurality of pixels, each pixel including a nanochain comprising: a first nanostructure, a second nanostructure, and a third nanostructure, wherein size of the first nanostructure is larger than that of the second nanostructure, and size of the second nanostructure is larger than that of the third nanostructure, and wherein the first nanostructure, the second nanostructure, and the third nanostructure are positioned on a substrate such that when the nanochain is excited by an energy, an optical field between the second nanostructure and the third nanostructure is stronger than an optical field between the first nanostructure and the second nanostructure, wherein the array is configured to receive a sample; and a detector arranged to collect spectral data from a plurality of pixels of the array.

  9. The current state of physical activity and exercise programs in German-speaking, Swiss psychiatric hospitals: results from a brief online survey

    Directory of Open Access Journals (Sweden)

    Br

    2016-06-01

    Full Text Available Serge Brand,1,2 Flora Colledge,2 Nadja Beeler,2 Uwe Pühse,2 Nadeem Kalak,1 Dena Sadeghi Bahmani,1 Thorsten Mikoteit,1 Edith Holsboer-Trachsler,1 Markus Gerber2 1Psychiatric Clinics of the University of Basel, Center for Affective, Stress and Sleep Disorders, 2Department of Sport, Exercise and Health, Sport Science Section, University of Basel, Basel, Switzerland Background: Physical activity and exercise programs (PAEPs are an important factor in increasing and maintaining physical and mental health. This holds particularly true for patients with psychiatric disorders undergoing treatment in a psychiatric hospital. To understand whether the benefits reported in the literature are mirrored in current treatment modalities, the aim of the present study was to assess the current state of PAEPs in psychiatric hospitals in the German-speaking part of Switzerland. Methods: All psychiatric hospitals (N=55 in the German-speaking part of Switzerland were contacted in spring 2014. Staff responsible for PAEPs were asked to complete an online questionnaire covering questions related to PAEPs such as type, frequency, staff training, treatment rationale, importance of PAEPs within the treatment strategy, and possible avenues to increase PAEPs. Results: Staff members of 48 different psychiatric hospitals completed the survey. Hospitals provided the following therapeutic treatments: relaxation techniques (100%, sports therapy (97%, activity-related psychotherapeutic interventions (95%, physiotherapy (85%, body therapies (59%, far-east techniques (57%, and hippotherapy (22%. Frequencies ranged from once/week to five times/week. Approximately 25% of patients participated in the PAEPs. Interventions were offered irrespective of psychiatric disorders. PAEP providers wanted and needed more vocational training. Conclusion: All participating psychiatric hospitals offer a broad variety of PAEPs in their treatment curricula. However, the majority of inpatients do not

  10. Update of the BIPM comparison BIPM.RI(II)-K1.F-18 of activity measurements of the radionuclide 18F to include the 2010 result of the LNE-LNHB (France)

    Science.gov (United States)

    Michotte, C.; Ratel, G.; Courte, S.; Cassette, P.; Moune, M.

    2016-01-01

    Since 2001, six national metrology institutes (NMI) have submitted seven samples of known activity of 18F to the International Reference System (SIR) for activity comparison at the Bureau International des Poids et Mesures (BIPM), with comparison identifier BIPM.RI(II)-K1.F-18. The values of the activity submitted were between about 1 MBq and 18 MBq. The primary standardization result for the LNE-LNHB, France, replaces their earlier result of 2002 and the key comparison reference value (KCRV) has been recalculated. In the frame of the BIPM.RI(II)-K4.F18 comparison, the NPL updated their result in the KCDB. Consequently there are now five results in the BIPM.RI(II)-K1.F-18 comparison. The degrees of equivalence between each equivalent activity measured in the SIR and the updated KCRV have been calculated and the results are given in the form of a table. A graphical presentation is also given. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCRI, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

  11. Very low dose fetal exposure to Chernobyl contamination resulted in increases in infant leukemia in Europe and raises questions about current radiation risk models.

    Science.gov (United States)

    Busby, Christopher C

    2009-12-01

    Following contamination from the Chernobyl accident in April 1986 excess infant leukemia (0-1 y) was reported from five different countries, Scotland, Greece, Germany, Belarus and Wales and Scotland combined. The cumulative absorbed doses to the fetus, as conventionally assessed, varied from 0.02 mSv in the UK through 0.06 mSv in Germany, 0.2 mSv in Greece and 2 mSv in Belarus, where it was highest. Nevertheless, the effect was real and given the specificity of the cohort raised questions about the safety of applying the current radiation risk model of the International Commission on Radiological Protection (ICRP) to these internal exposures, a matter which was discussed in 2000 by Busby and Cato and also in the reports of the UK Committee examining Radiation Risk from Internal Emitters. Data on infant leukemia in the United Kingdom, chosen on the basis of the cohorts defined by the study of Greece were supplied by the UK Childhood Cancer Research Group. This has enabled a study of leukemia in the combined infant population of 15,466,845 born in the UK, Greece, and Germany between 1980 and 1990. Results show a statistically significant excess risk RR = 1.43 (95% CI 1.13 < RR < 1.80 (2-tailed); p = 0.0025) in those born during the defined peak exposure period of 01/07/86 to 31/12/87 compared with those born between 01/01/80 and 31/12/85 and 01/01/88 and 31/12/90. The excess risks in individual countries do not increase monotonically with the conventionally calculated doses, the relation being biphasic, increasing sharply at low doses and falling at high doses. This result is discussed in relation to fetal/cell death at higher doses and also to induction of DNA repair. Since the cohort is chosen specifically on the basis of exposure to internal radionuclides, the result can be expressed as evidence for a significant error in the conventional modeling for such internal fetal exposures.

  12. Very Low Dose Fetal Exposure to Chernobyl Contamination Resulted in Increases in Infant Leukemia in Europe and Raises Questions about Current Radiation Risk Models

    Directory of Open Access Journals (Sweden)

    Christopher C. Busby

    2009-12-01

    Full Text Available Following contamination from the Chernobyl accident in April 1986 excess infant leukemia (0–1 y was reported from five different countries, Scotland, Greece, Germany, Belarus and Wales and Scotland combined. The cumulative absorbed doses to the fetus, as conventionally assessed, varied from 0.02 mSv in the UK through 0.06 mSv in Germany, 0.2 mSv in Greece and 2 mSv in Belarus, where it was highest. Nevertheless, the effect was real and given the specificity of the cohort raised questions about the safety of applying the current radiation risk model of the International Commission on Radiological Protection (ICRP to these internal exposures, a matter which was discussed in 2000 by Busby and Cato [7,8] and also in the reports of the UK Committee examining Radiation Risk from Internal Emitters. Data on infant leukemia in the United Kingdom, chosen on the basis of the cohorts defined by the study of Greece were supplied by the UK Childhood Cancer Research Group. This has enabled a study of leukemia in the combined infant population of 15,466,845 born in the UK, Greece, and Germany between 1980 and 1990. Results show a statistically significant excess risk RR = 1.43 (95% CI 1.13 < RR < 1.80 (2-tailed; p = 0.0025 in those born during the defined peak exposure period of 01/07/86 to 31/12/87 compared with those born between 01/01/80 and 31/12/85 and 01/01/88 and 31/12/90. The excess risks in individual countries do not increase monotonically with the conventionally calculated doses, the relation being biphasic, increasing sharply at low doses and falling at high doses. This result is discussed in relation to fetal/cell death at higher doses and also to induction of DNA repair. Since the cohort is chosen specifically on the basis of exposure to internal radionuclides, the result can be expressed as evidence for a significant error in the conventional modeling for such internal fetal exposures.

  13. The antibacterial substance, taurolidine in the second/third-line treatment of very advanced stage IV melanoma including brain metastases: results of a phase 2, open-label study.

    Science.gov (United States)

    Imhof, Laurence; Goldinger, Simone M; Baumann, Katrin; Schad, Karin; French, Lars E; Röthlisberger, Peter; Dummer, Reinhard

    2011-02-01

    The efficacy and tolerability of taurolidine, an antibacterial substance, was evaluated in a phase 2 trial enrolling patients with advanced melanoma. The treatment schedule consisted of daily taurolidine (20 g) administered intravenously for 5 days per week for 3 consecutive weeks followed by 1 week of rest. One cycle comprised of 28 days. A maximum of six cycles could be administered. Sixteen patients were assessable for tumor response, seven of whom had brain metastases. Three patients (18.8%) achieved disease stabilization, including a patient with a primary mucosal melanoma of the nasal cavity who had a marked locoregional response with disease stabilization of the distant metastases. Thirteen patients had disease progression. Median overall survival was 46±1 days. Adverse events were moderate and mainly gastrointestinal. Treatment with taurolidine has no activity in patients with advanced melanoma.

  14. The efficacy and safety of treatments for acute gout: results from a series of systematic literature reviews including Cochrane reviews on intraarticular glucocorticoids, colchicine, nonsteroidal antiinflammatory drugs, and interleukin-1 inhibitors.

    Science.gov (United States)

    Wechalekar, Mihir D; Vinik, Ophir; Moi, John H Y; Sivera, Francisca; van Echteld, Irene A A M; van Durme, Caroline; Falzon, Louise; Bombardier, Claire; Carmona, Loreto; Aletaha, Daniel; Landewé, Robert B; van der Heijde, Désirée M F M; Buchbinder, Rachelle

    2014-09-01

    To determine the efficacy and safety of glucocorticoids (GC), colchicine, nonsteroidal antiinflammatory drugs (NSAID), interleukin-1 (IL-1) inhibitors, and paracetamol to treat acute gout. We searched MEDLINE, EMBASE, and Cochrane Central Register of Controlled Trials to September 2011. Randomized controlled trials (RCT) or quasi-RCT in adults with acute gout that compared GC, colchicine, NSAID, IL-1 inhibitors, and paracetamol to no treatment, placebo, another intervention, or combination therapy were included. Two authors independently extracted data and assessed risk of bias. Primary endpoints were pain and adverse events. Data were pooled where appropriate. Twenty-six trials evaluating GC (N = 5), NSAID (N = 21), colchicine (N = 2), and canakinumab (N = 1) were included. No RCT assessed paracetamol or intraarticular (IA) GC. No RCT compared systemic GC with placebo. Moderate quality evidence (3 trials) concluded that systemic GC were as effective as NSAID but safer. Low quality evidence (1 trial) showed that both high- and low-dose colchicine were more effective than placebo, and low-dose colchicine was no different to placebo with respect to safety but safer than high-dose colchicine. Low quality evidence (1 trial) showed no difference between NSAID and placebo with regard to pain or inflammation. No NSAID was superior to another. Moderate quality evidence (1 trial) found that 150 mg canakinumab was more effective than a single dose of intramuscular GC (40 mg triamcinolone) and equally safe. GC, NSAID, low-dose colchicine, and canakinumab all effectively treat acute gout. There was insufficient evidence to rank them. Systemic GC appeared safer than NSAID and lower-dose colchicine was safer than higher-dose colchicine.

  15. Morphology and flow fields of three-dimensional dunes, Rio Paraná, Argentina: Results from simultaneous multibeam echo sounding and acoustic Doppler current profiling

    Science.gov (United States)

    Parsons, D. R.; Best, J. L.; Orfeo, O.; Hardy, R. J.; Kostaschuk, R.; Lane, S. N.

    2005-12-01

    Most past studies of river dune dynamics have concentrated on two-dimensional (2-D) bed forms, with constant heights and straight crest lines transverse to the flow, and their associated turbulent flow structure. This morphological simplification imposes inherent limitations on the interpretation and understanding of dune form and flow dynamics in natural channels, where dune form is predominantly three-dimensional. For example, studies over 2-D forms neglect the significant influence that lateral flows and secondary circulation may have on the flow structure and thus dune morphology. This paper details a field study of a swath of 3-D dunes in the Rio Paraná, Argentina. A large (0.35 km wide, 1.2 km long) area of dunes was surveyed using a multibeam echo sounder (MBES) that provided high-resolution 3-D detail of the river bed. Simultaneous with the MBES survey, 3-D flow information was obtained with an acoustic Doppler current profiler (ADCP), revealing a complicated pattern of dune morphology and associated flow structure within the swath. Dune three-dimensionality appears intimately connected to the morphology of the upstream dune, with changes in crest line curvature and crest line bifurcations/junctions significantly influencing the downstream dune form. Dunes with lobe or saddle-shaped crest lines were found to have larger, more structured regions of vertical velocity with smaller separation zones than more 2-D straight-crested dunes. These results represent the first integrated study of 3-D dune form and mean flow structure from the field and show several similarities to recent laboratory models of flow over 3-D dunes.

  16. Current worldwide nuclear cardiology practices and radiation exposure: results from the 65 country IAEA Nuclear Cardiology Protocols Cross-Sectional Study (INCAPS)

    Science.gov (United States)

    Einstein, Andrew J.; Pascual, Thomas N. B.; Mercuri, Mathew; Karthikeyan, Ganesan; Vitola, João V.; Mahmarian, John J.; Better, Nathan; Bouyoucef, Salah E.; Hee-Seung Bom, Henry; Lele, Vikram; Magboo, V. Peter C.; Alexánderson, Erick; Allam, Adel H.; Al-Mallah, Mouaz H.; Flotats, Albert; Jerome, Scott; Kaufmann, Philipp A.; Luxenburg, Osnat; Shaw, Leslee J.; Underwood, S. Richard; Rehani, Madan M.; Kashyap, Ravi; Paez, Diana; Dondi, Maurizio

    2015-01-01

    Aims To characterize patient radiation doses from nuclear myocardial perfusion imaging (MPI) and the use of radiation-optimizing ‘best practices’ worldwide, and to evaluate the relationship between laboratory use of best practices and patient radiation dose. Methods and results We conducted an observational cross-sectional study of protocols used for all 7911 MPI studies performed in 308 nuclear cardiology laboratories in 65 countries for a single week in March–April 2013. Eight ‘best practices’ relating to radiation exposure were identified a priori by an expert committee, and a radiation-related quality index (QI) devised indicating the number of best practices used by a laboratory. Patient radiation effective dose (ED) ranged between 0.8 and 35.6 mSv (median 10.0 mSv). Average laboratory ED ranged from 2.2 to 24.4 mSv (median 10.4 mSv); only 91 (30%) laboratories achieved the median ED ≤ 9 mSv recommended by guidelines. Laboratory QIs ranged from 2 to 8 (median 5). Both ED and QI differed significantly between laboratories, countries, and world regions. The lowest median ED (8.0 mSv), in Europe, coincided with high best-practice adherence (mean laboratory QI 6.2). The highest doses (median 12.1 mSv) and low QI (4.9) occurred in Latin America. In hierarchical regression modelling, patients undergoing MPI at laboratories following more ‘best practices’ had lower EDs. Conclusion Marked worldwide variation exists in radiation safety practices pertaining to MPI, with targeted EDs currently achieved in a minority of laboratories. The significant relationship between best-practice implementation and lower doses indicates numerous opportunities to reduce radiation exposure from MPI globally. PMID:25898845

  17. Substance use among women receiving post-rape medical care, associated post-assault concerns and current substance abuse: Results from a national telephone household probability sample

    Science.gov (United States)

    McCauley, Jenna L.; Kilpatrick, Dean G.; Walsh, Kate; Resnick, Heidi S.

    2013-01-01

    Objective To examine post-rape substance use, associated post rape medical and social concern variables, and past year substance abuse among women reporting having received medical care following a most recent or only lifetime incident of rape. Method Using a subsample of women who received post-rape medical care following a most recent or only rape incident (n=104) drawn from a national household probability sample of U.S. women, the current study described the extent of peritraumatic substance use, past year substance misuse behaviors, post-rape HIV and pregnancy concerns, and lifetime mental health service utilization as a function of substance use at time of incident. Results One-third (33%) of women seeking post-rape medical attention reported consuming alcohol or drugs at the time of their rape incident. Nearly one in four (24.7%) and one in seven (15%) women seeking medical attention following their most recent rape incident endorsed drug (marijuana, illicit, non-medical use of prescription drugs, or club drug) use or met substance abuse criteria, respectively, in the past year. One in twelve (8.4%) women reported at least monthly binge drinking in the past year. Approximately two-thirds of women reported seeking services for mental health needs in their lifetime. Post-rape concerns among women reporting peritraumatic substance use were not significantly different from those of women not reporting such use. Conclusions Substance use was reported by approximately one-third of women and past year substance abuse was common among those seeking post-rape medical care. Implications for service delivery, intervention implementation, and future research are discussed. PMID:23380490

  18. Current practice vs. guideline based imaging in abdominal radiology in the German speaking area. Results of an online survey; Versorgungsrealitaet vs. leitliniengerechte Bildgebung in der Abdominalradiologie im deutschsprachigen Raum. Ergebnisse einer Online-Umfrage

    Energy Technology Data Exchange (ETDEWEB)

    Schreyer, A.G. [University Hospital Regenburg (Germany). Dept. of Radiology; Wessling, J. [Clemens Hospital Muenchen (Germany). Dept. of Radiology; Grenacher, L. [Diagnostic Muenchen (Germany). Diagnostic Imaging Center

    2016-03-15

    The working group for abdominal imaging within the German Roentgen Society (DRG) performed an online survey amongst radiologist concerning the current status of techniques for abdominal imaging. The results of this survey were compared with the most recent guidelines. We performed an online survey open for all members of the DRG during a 76-day period with 65 questions and an overall estimated time for finishing the questionnaire of 15 minutes concerning technical specifications for abdominal radiological imaging. The results were evaluated using descriptive statistics. 90 of all participants, who filled out the survey covering more than 80 % of the questions, were included in the statistical evaluation. 27 % of all participants were registered radiologists while 73 % represented radiologists working in a hospital. Most participants worked in a managerial position. The participants gave detailed information regarding the radiological techniques used in dedicated organ systems (esophagus, stomach, pancreas, liver, small intestines, colon) regarding acquired contrast phases and oral and intravenous administration of contrast medium. The results confirm that most radiologists participating in this survey perform their examinations and choose their modalities in conformity with the current existing clinical guidelines. Because most clinical guidelines do not specify radiological examinations in detail, there is a noteworthy heterogeneity of the acquired contrast phases and major divergence in terms of technical parameters. Therefore a joint radiological effort should be initiated for developing and publishing updated radiological parameters for abdominal imaging.

  19. Update of the BIPM comparison BIPM.RI(II)-K1.Bi-207 of activity measurements of the radionuclide 207Bi to include the 2010 result of the LNE-LNHB (France)

    Science.gov (United States)

    Michotte, C.; Ratel, G.; Courte, S.; Bobin, C.; Moune, M.

    2015-01-01

    In 2010, the Laboratoire National de Métrologie et d'Essais-Laboratoire National Henri Becquerel (LNE-LNHB) submitted one sample of known activity of 207Bi to the International Reference System for activity comparison at the Bureau International des Poids et Mesures, with comparison identifier BIPM.RI(II)-K1.Bi-207. The value of the activity submitted was about 180 kBq. There is now one result in the BIPM.RI(II)-K1.Bi-207 comparison. The key comparison reference value (KCRV) has been evaluated for the first time using the LNE-LNHB result and a PTB result dating 1982. The degree of equivalence between the LNE-LNHB equivalent activity measured in the SIR and the KCRV has been calculated and is reported. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCRI, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

  20. Late Mesozoic and Cenozoic thermotectonic evolution of the central Brooks Range and adjacent North Slope foreland basin, Alaska: Including fission track results from the Trans-Alaska Crustal Transect (TACT)

    Science.gov (United States)

    O'Sullivan, P. B.; Murphy, J.M.; Blythe, A.E.

    1997-01-01

    Apatite fission track data are used to evaluate the thermal and tectonic history of the central Brooks Range and the North Slope foreland basin in northern Alaska along the northern leg of the Trans-Alaska Crustal Transect (TACT). Fission track analyses of the detrital apatite grains in most sedimentary units resolve the timing of structures and denudation within the Brooks Range, ranging in scale from the entire mountain range to relatively small-scale folds and faults. Interpretation of the results indicates that rocks exposed within the central Brooks Range cooled rapidly from paleotemperatures 110?? to 50??C during discrete episodes at ???100??5 Ma, ???60??4 Ma, and ???24??3 Ma, probably in response to kilometer-scale denudation. North of the mountain front, rocks in the southern half of the foreland basin were exposed to maximum paleotemperatures 110??C in the Late Cretaceous to early Paleocene as a result of burial by Upper Jurassic and Cretaceous sedimentary rocks. Rapid cooling from these elevated paleotemperatures also occurred due to distinct episodes of kilometer-scale denudation at ???60??4 Ma, 46??3 Ma, 35??2 Ma, and ???24??3 Ma. Combined, the apatite analyses indicate that rocks exposed along the TACT line through the central Brooks Range and foreland basin experienced episodic rapid cooling throughout the Late Cretaceous and Cenozoic in response to at least three distinct kilometer-scale denudation events. Future models explaining orogenic events in northern Alaska must consider these new constraints from fission track thermochronology. Copyright 1997 by the American Geophysical Union.

  1. Genetic association of gastric cancer with miRNA clusters including the cancer-related genes MIR29, MIR25, MIR93 and MIR106: results from the EPIC-EURGAST study.

    Science.gov (United States)

    Espinosa-Parrilla, Yolanda; Muñoz, Xavier; Bonet, Catalina; Garcia, Nadia; Venceslá, Adoración; Yiannakouris, Nikos; Naccarati, Alessio; Sieri, Sabina; Panico, Salvatore; Huerta, José M; Barricarte, Aurelio; Menéndez, Virginia; Sánchez-Cantalejo, Emilio; Dorronsoro, Miren; Brennan, Paul; Duarte-Salles, Talita; B As Bueno-de-Mesquita, H; Weiderpass, Elisabete; Lund, Eiliv; Clavel-Chapelon, Françoise; Boutron-Ruault, Marie-Christine; Racine, Antoine; Numans, Mattijs E; Tumino, Rosario; Canzian, Federico; Campa, Daniele; Sund, Malin; Johansson, Mattias; Ohlsson, Bodil; Lindkvist, Björn; Overvad, Kim; Tjønneland, Anne; Palli, Domenico; Travis, Ruth C; Khaw, Kay-Tee; Wareham, Nick; Boeing, Heiner; Nesi, Gabriella; Riboli, Elio; Gonzalez, Carlos A; Sala, Núria

    2014-11-01

    MicroRNAs (miRNAs) are post-transcriptional gene regulators involved in a wide range of biological processes including tumorigenesis. Deregulation of miRNA pathways has been associated with cancer but the contribution of their genetic variability to this disorder is poorly known. We analyzed the genetic association of gastric cancer (GC) and its anatomical and histological subtypes, with 133 single-nucleotide polymorphisms (SNPs) tagging 15 isolated miRNAs and 24 miRNA clusters potentially involved in cancer, in 365 GC cases and 1,284 matched controls within the European Prospective Investigation into Cancer and Nutrition cohort. Various SNPs were associated with GC under the log-additive model. Furthermore, several of these miRNAs passed the gene-based permutation test when analyzed according to GC subtypes: three tagSNPs of the miR-29a/miR-29b-1 cluster were associated with diffuse subtype (minimum p-value = 1.7 × 10(-4) ; odds ratio, OR = 1.72; 95% confidence interval, CI = 1.30-2.28), two tagSNPs of the miR-25/miR-93/miR-106b cluster were associated with cardia GC (minimum p-value = 5.38 × 10(-3) ; OR = 0.56, 95% CI = 0.37-0.86) and one tagSNP of the miR-363/miR-92a-2/miR-19b-2/miR-20b/miR-18b/miR-106a cluster was associated with noncardia GC (minimum p-value = 5.40 × 10(-3) ; OR = 1.41, 95% CI = 1.12-1.78). Some functionally validated target genes of these miRNAs are implicated in cancer-related processes such as methylation (DNMT3A, DNMT3B), cell cycle (E2F1, CDKN1A, CDKN1C), apoptosis (BCL2L11, MCL1), angiogenesis (VEGFA) and progression (PIK3R1, MYCN). Furthermore, we identified genetic interactions between variants tagging these miRNAs and variants in their validated target genes. Deregulation of the expression of these miRNAs in GC also supports our findings, altogether suggesting for the fist time that genetic variation in MIR29, MIR25, MIR93 and MIR106b may have a critical role in genetic susceptibility to GC and

  2. Batteries not included

    Energy Technology Data Exchange (ETDEWEB)

    Valiante, U.

    1999-01-01

    Serious questions have arisen about the environmental damage caused by cadmium from rechargeable nickel cadmium batteries in municipal solid waste. Sweden, Belgium, several American states and Canadian provinces either have enacted, or are contemplating legislation to address disposal of cadmium-containing batteries. In a preemptive strike, industry is now developing its own recycling initiatives through the Rechargeable Battery Recycling Corporation (RBRC), established in the USA in 1996, and launched in Ontario in September 1997. The primary role of RBRC in Canada is to collect licensee funds from participating battery manufacturers and administer Ni-Cd battery recycling programs. RBRC is also tasked to establish consensus within provincial and federal regulatory bodies with regard to the issue of Ni-Cd battery waste management. Mounting concerns are expressed about conflicting statistics as to the volume of batteries collected for recycling, and more particularly, about the method of recycling that RBRC may be contemplating. The fear is that in the absence of a profitable incentive to battery distributors, or a profitable product that might result from the recycled material, combined with the pressure of the high cost of recycling Ni-Cd batteries, many of the recovered batteries could end up in landfills sites for hazardous wastes. This is especially likely since Ni-Cd batteries are not banned from landfill sites in Ontario. It is the view of this author that while RBRC`s `charge up to recycle` program makes all the right noises, it lacks a meaningful approach to actually increase diversion, measure results, or to prevent Ni-Cd rechargeable batteries from entering the solid waste stream.

  3. A contribution to quantum cryptography in finite-dimensional systems including further results from the field of quantum information theory; Ein Beitrag zur Quantenkryptographie in endlichdimensionalen Systemen nebst weiteren Ergebnissen aus dem Gebiet der Quanteninformationstheorie

    Energy Technology Data Exchange (ETDEWEB)

    Ranade, Kedar S.

    2009-02-04

    This PhD thesis deals with quantum-cryptographic protocols which allow general finite-dimensional quantum systems (qudits) as carriers of information in contrast to the predominantly used two-dimensional quantum systems (qubits). The main focus of investigations is the maximum tolerable error rate of such protocols and its behaviour as a function of the dimension of the information carriers. For this purpose, several concepts are introduced which allow the treatment of this problem. In particular, protocols are presented which work up to a maximum tolerate error rate, and it is shown that a wide class of protocols cannot be used for higher error rates. Among other things, it turns out that the maximum tolerable error rate for two-basis protocols increases up to 50% for high dimensions. Apart from the above-mentioned main subjects of this thesis, some other results from the field of quantum information theory are given, which were achieved during this PhD project. (orig.)

  4. Biodiversity conservation including uncharismatic species

    DEFF Research Database (Denmark)

    Muñoz, Joaquin

    2007-01-01

    Recent papers mention ideas on the topics of biodiversity conservation strategies and priorities (Redford et al. 2003; Lamoreux et al. 2006; Rodrı´guez et al. 2006), the current status of biodiversity (Loreau et al. 2006), the obligations of conservation biologists regarding management policies...... (Chapron 2006; Schwartz 2006), and the main threats to biodiversity (including invasive species) (Bawa 2006). I suggest, however, that these articles do not really deal with biodiversity. Rather, they all focus on a few obviously charismatic groups (mammals, birds, some plants, fishes, human culture...

  5. Risk Factors for Obesity at Age 3 in Alaskan Children, Including the Role of Beverage Consumption: Results from Alaska PRAMS 2005-2006 and Its Three-Year Follow-Up Survey, CUBS, 2008-2009

    Science.gov (United States)

    Wojcicki, Janet M.; Young, Margaret B.; Perham-Hester, Katherine A.; de Schweinitz, Peter; Gessner, Bradford D.

    2015-01-01

    Background Prenatal and early life risk factors are associated with childhood obesity. Alaska Native children have one of the highest prevalences of childhood obesity of all US racial/ethnic groups. Methods Using the Pregnancy Risk Assessment Monitoring System (PRAMS) and the follow-up survey at 3 years of age (CUBS), we evaluated health, behavioral, lifestyle and nutritional variables in relation to obesity (95th percentile for body mass index (BMI)) at 3 years of age. Multivariate logistic regression modeling was conducted using Stata 12.0 to evaluate independent risk factors for obesity in non-Native and Alaska Native children. Results We found an obesity prevalence of 24.9% in all Alaskan and 42.2% in Alaska Native 3 year olds. Among Alaska Native children, obesity prevalence was highest in the Northern/Southwest part of the state (51.6%, 95%CI (42.6-60.5)). Independent predictive factors for obesity at age 3 years in Alaska non-Native children were low income (obesity (OR 2.01, 95%CI 1.01-4.01) and longer duration of breastfeeding was protective (OR 0.95, 95%CI 0.91-0.995). Among Alaska Native children, predictive factors were witnessing domestic violence/abuse as a 3 year-old (OR 2.28, 95%CI 1.17-7.60). Among obese Alaska Native children, there was an increased daily consumption of energy dense beverages in the Northern/Southwest region of the state, which may explain higher rates of obesity in this part of the state. Conclusions The high prevalence of obesity in Alaska Native children may be explained by differences in lifestyle patterns and food consumption in certain parts of the state, specifically the Northern/Southwest region, which have higher consumption of energy dense beverages. PMID:25793411

  6. Induction motor starting current

    Energy Technology Data Exchange (ETDEWEB)

    Arneaud, J.M.; Langman, R.A. [Tasmania Univ., Hobart, TAS (Australia)

    1995-12-31

    Large errors may occur if leakage path saturation is neglected when reduced-voltage test results are used to predict the direct-on-line starting current of induction motors. The results of applying three existing and two new methods for starting current prediction are compared with test data from 52 motors. A quantitative assessment is made of the probable reduction in error that would be achieved by increasing the number of available sets of reduced-voltage, locked rotor test results or by including slot design data. Guidelines are given for selecting an appropriate predictive method. (author). 4 tabs., 1 fig., 6 refs.

  7. Theory including future not excluded

    DEFF Research Database (Denmark)

    Nagao, K.; Nielsen, H.B.

    2013-01-01

    We study a complex action theory (CAT) whose path runs over not only past but also future. We show that, if we regard a matrix element defined in terms of the future state at time T and the past state at time TA as an expectation value in the CAT, then we are allowed to have the Heisenberg equation......, Ehrenfest's theorem, and the conserved probability current density. In addition,we showthat the expectation value at the present time t of a future-included theory for large T - t and large t - T corresponds to that of a future-not-included theory with a proper inner product for large t - T. Hence, the CAT...

  8. Is the current pertussis incidence only the results of testing? A spatial and space-time analysis of pertussis surveillance data using cluster detection methods and geographically weighted regression modelling

    Science.gov (United States)

    Kauhl, Boris; Heil, Jeanne; Hoebe, Christian J. P. A.; Schweikart, Jürgen; Krafft, Thomas; Dukers-Muijrers, Nicole H. T. M.

    2017-01-01

    Background Despite high vaccination coverage, pertussis incidence in the Netherlands is amongst the highest in Europe with a shifting tendency towards adults and elderly. Early detection of outbreaks and preventive actions are necessary to prevent severe complications in infants. Efficient pertussis control requires additional background knowledge about the determinants of testing and possible determinants of the current pertussis incidence. Therefore, the aim of our study is to examine the possibility of locating possible pertussis outbreaks using space-time cluster detection and to examine the determinants of pertussis testing and incidence using geographically weighted regression models. Methods We analysed laboratory registry data including all geocoded pertussis tests in the southern area of the Netherlands between 2007 and 2013. Socio-demographic and infrastructure-related population data were matched to the geo-coded laboratory data. The spatial scan statistic was applied to detect spatial and space-time clusters of testing, incidence and test-positivity. Geographically weighted Poisson regression (GWPR) models were then constructed to model the associations between the age-specific rates of testing and incidence and possible population-based determinants. Results Space-time clusters for pertussis incidence overlapped with space-time clusters for testing, reflecting a strong relationship between testing and incidence, irrespective of the examined age group. Testing for pertussis itself was overall associated with lower socio-economic status, multi-person-households, proximity to primary school and availability of healthcare. The current incidence in contradiction is mainly determined by testing and is not associated with a lower socioeconomic status. Discussion Testing for pertussis follows to an extent the general healthcare seeking behaviour for common respiratory infections, whereas the current pertussis incidence is largely the result of testing. More

  9. Cancer Treatment - Cancer Currents Blog

    Science.gov (United States)

    A catalog of posts from NCI’s Cancer Currents blog on cancer treatment research. Includes posts on new treatments for cancer and their effects, clinical trial results, and overcoming treatment resistance.

  10. Positron emission tomography 2008 in Germany. Results of the query and current status; Positronenemissionstomographie 2008 in Deutschland. Ergebnisse der Erhebung und Standortbestimmung

    Energy Technology Data Exchange (ETDEWEB)

    Kotzerke, J.; Oehme, L. [Universitaetsklinikum Carl Gustav Carus, Technische Univ. Dresden (Germany). Klinik und Poliklinik fuer Nuklearmedizin; Lindner, O. [Herz- und Diabeteszentrum Nordrhein-Westfalen, Bad Oeynhausen (Germany). Inst. fuer Radiologie, Nuklearmedizin und Molekulare Bildgebung; Hellwig, D. [Universitaetsklinikum des Saarlandes, Homburg/Saar (Germany). Klinik fuer Nuklearmedizin

    2010-07-01

    Aim: The working group on positron emission tomography (PET) of the DGN (German Society of Nuclear Medicine) initiated this first survey to collect and analyse information on the practise of PET in Germany in the year 2008. Methods: A questionnaire was sent to PET performing facilities (medical practices, hospitals, university hospitals and others) for retrospective data acquisition. Details regarding the equipment and examination procedures were examined as well as indications and number of studies. In addition, the role of PET within the diagnostic process was evaluated. Results: Responses from 65 sites were analysed. Their technical equipment consisted of 77 PET scanners (40 of them were combined PET/CT devices). About 63 500 PET studies had been performed with 86% in the field of oncology, 8% in neurology and 3% in cardiology. The radiotracers were labelled with {sup 18}F in 91% of the studies, whereas {sup 68}Ga was used in 4% and {sup 11}C in 3%. The analyses revealed lung tumours as the most investigated tumour entity, followed by malignant lymphoma, tumours of the gastro-intestinal tract and prostate cancer (about 14 000, 6000, 5000 and 2000). Corresponding to the new scanners and software procedures, the number of studies with attenuation correction by CT was high (68%) and nearly all studies were reconstructed iteratively (99%). The PET images were analysed quantitatively in the majority of cases (91%). The clinical reports, which included image documentation for the greater part, were posted regularly within 3 days. However, in 70% of the sites electronic transfer possibilities were used additionally to speed up the diagnostic process. The high standard of quality was demonstrated by the fact, that 40 facilities were engaged in a tumour board. Further on, one third of the physicians had gained a PET certification awarded by the DGN. Conclusion: Relative to the high general standard of diagnostic instrumentation in Germany, PET is less established, in

  11. Preliminary results of sero-conversion of kids and lambs vaccinated with Brucella melitensis rev -1 strain. Current achievements and feature challenges on brucellosis

    Directory of Open Access Journals (Sweden)

    XHELIL KOLECI

    2014-06-01

    Full Text Available Sheep and goat brucellosis is an endemic and most important infectious disease of livestock in Albania. It continues to remain a frequent zoonotic disease and an important public health issue. Among available strategies, mass vaccination is an acceptable, cost effective approach, and is a widely used strategy in many countries including some neighbouring Balkan countries. Albanian veterinary services supported by the European Union-funded PAZA project (Protection Against Zoonotic diseases, Albania applied two successive annual mass vaccination campaigns that aimed to vaccinate all small ruminants in the country. These two campaigns aimed at significantly reducing disease spread, however, a small number of infection foci could remain and persist in some parts of country. Post-vaccination surveillance is essential for early detection and proper control of cases of brucellosis that might re-emerge. Limitation major complication arising from mass vaccination is the difficulty of interpretation of the results of serological tests conducted to diagnose the disease. The aim of this study was to evaluate the proportion of vaccinated animals that showed sero-conversion and the duration of detectable levels of agglutinins (antibody against brucellosis in vaccinated animals. Methods. In total, 69 individual animals, 23 lambs and 46 kids aged from 4 to 7 months, were sampled at monthly intervals. Jugular blood was collected before vaccination and at intervals thereafter and tested by means of the Rose Bengal test. All animals were serologically negative before vaccination with modified live Brucella melitensis Rev.1 strain vaccine. Rose Bengal test was performed before vaccination, 18 days, 2, 3 and 4 months after vaccination. Results. Eighteen days after vaccination, 63 out of 69 animals (91.3% 82.6% of lambs (19 out of 23 lambs and 95.6% of goat kids (44 out of 46 showed strong sero-conversion in Rose Bengal test. The proportion of positive vaccinated

  12. Evaluation of JSAF EM Propagation Prediction Methods for Navy Continuous Training Environment/Fleet Synthetic Training Results and Recommendations: Part 1 - Evaluation of Current JSAF EM Propagation Modeling

    Science.gov (United States)

    2012-12-01

    FFACTR” which is a part of the Engineers Refractive Index Prediction System (EREPS) Tactical Decision Aid ( TDA ) developed by what is now SPAWARS SSC San...currently used in JSAF is “FFACTR” which is a part of the Engineers Refractive Index Prediction System (EREPS) Tactical Decision Aid ( TDA ) developed by what...Decision Aid ( TDA ) developed by what is now SPAWARS SSC San Diego in 1988. This model is no longer supported by SPAWARS or any other group and has been

  13. Polymerization of Included Monomers and Behaviour of Resulting Polymers

    Science.gov (United States)

    Choi, Soowhan; Amajjahe, Sadik; Ritter, Helmut

    Cyclodextrins (CDs) are of interest to synthetic chemists because of their chemical stability and the possibility to modify these molecules in a regioselective manner. For supramolecular chemistry CDs are of great importance, since they represent a homologous series of water-soluble and chiral host molecules which can be used as models for studying weak interactions. In addition, their low price provides motivation for the discovery of new applications. Thus, CDs are used for the solubilization and encapsulation of drugs, perfumes, and flavourings. These applications are due to their low toxicity and their biodegradablity. Finally, they are of general interest because they are obtained from a renewable resource, starch (Eggersdorfer, M., Warwel, S., Wulff, CT.: Nachwachsende Rohstoffe Perspektiven für die Chemie. VCH, Weinheim (1993) .

  14. Compendium of Current Total Ionizing Dose and Displacement Damage Results from NASA Goddard Space Flight Center and Selected NASA Electronic Parts and Packaging Program

    Science.gov (United States)

    Topper, Alyson D.; Campola, Michael J.; Chen, Dakai; Casey, Megan C.; Yau, Ka-Yen; Cochran, Donna J.; LaBel, Kenneth A.; Ladbury, Raymond L.; Lauenstein, Jean-Marie; Mondy, Timothy K.; hide

    2017-01-01

    Total ionizing dose and displacement damage testing was performed to characterize and determine the suitability of candidate electronics for NASA space utilization. Devices tested include optoelectronics, digital, analog, linear bipolar devices, and hybrid devices.

  15. Risk behaviors, prevalence of HIV and hepatitis C virus infection and population size of current injection drug users in a China-Myanmar border city: results from a Respondent-Driven Sampling Survey in 2012.

    Directory of Open Access Journals (Sweden)

    Lei Li

    Full Text Available BACKGROUND: Injection drug use has been the major cause of HIV/AIDS in China in the past two decades. We measured the prevalences of HIV and hepatitis C virus (HCV prevalence and their associated risk factors among current injection drug users (IDUs in Ruili city, a border region connecting China with Myanmar that has been undergoing serious drug use and HIV spread problems. An estimate of the number of current IDUs is also presented. METHODS: In 2012, Chinese IDUs who had injected within the past six months and aged ≥ 18 years were recruited using a respondent-driven sampling (RDS technique. Participants underwent interviews and serological testing for HIV, HBV, HCV and syphilis. Logistic regression indentified factors associated with HIV and HCV infections. Multiplier method was used to obtain an estimate of the size of the current IDU population via combining available service data and findings from our survey. RESULTS: Among 370 IDUs recruited, the prevalence of HIV and HCV was 18.3% and 41.5%, respectively. 27.1% of participants had shared a needle/syringe in their lifetime. Consistent condom use rates were low among both regular (6.8% and non-regular (30.4% partners. Factors independently associated with being HIV positive included HCV infection, having a longer history of injection drug use and experience of needle/syringe sharing. Participants with HCV infection were more likely to be HIV positive, have injected more types of drugs, have shared other injection equipments and have unprotected sex with regular sex partners. The estimated number of current IDUs in Ruili city was 2,714 (95% CI: 1,617-5,846. CONCLUSIONS: IDUs may continue to be a critical subpopulation for transmission of HIV and other infections in this region because of the increasing population and persistent high risk of injection and sexual behaviours. Developing innovative strategies that can improve accessibility of current harm reduction services and incorporate

  16. The current state of physical activity and exercise programs in German-speaking, Swiss psychiatric hospitals: results from a brief online survey.

    Science.gov (United States)

    Brand, Serge; Colledge, Flora; Beeler, Nadja; Pühse, Uwe; Kalak, Nadeem; Sadeghi Bahmani, Dena; Mikoteit, Thorsten; Holsboer-Trachsler, Edith; Gerber, Markus

    2016-01-01

    Physical activity and exercise programs (PAEPs) are an important factor in increasing and maintaining physical and mental health. This holds particularly true for patients with psychiatric disorders undergoing treatment in a psychiatric hospital. To understand whether the benefits reported in the literature are mirrored in current treatment modalities, the aim of the present study was to assess the current state of PAEPs in psychiatric hospitals in the German-speaking part of Switzerland. All psychiatric hospitals (N=55) in the German-speaking part of Switzerland were contacted in spring 2014. Staff responsible for PAEPs were asked to complete an online questionnaire covering questions related to PAEPs such as type, frequency, staff training, treatment rationale, importance of PAEPs within the treatment strategy, and possible avenues to increase PAEPs. Staff members of 48 different psychiatric hospitals completed the survey. Hospitals provided the following therapeutic treatments: relaxation techniques (100%), sports therapy (97%), activity-related psychotherapeutic interventions (95%), physiotherapy (85%), body therapies (59%), far-east techniques (57%), and hippotherapy (22%). Frequencies ranged from once/week to five times/week. Approximately 25% of patients participated in the PAEPs. Interventions were offered irrespective of psychiatric disorders. PAEP providers wanted and needed more vocational training. All participating psychiatric hospitals offer a broad variety of PAEPs in their treatment curricula. However, the majority of inpatients do not participate in PAEPs. Furthermore, those who do participate cannot continue to do so following discharge. PAEP providers need specific extended vocational trainings and believe that the potential of PA should be improved.

  17. 上海市透析登记及其结果分析%Current status of dialysis therapy in Shanghai (results from Shanghai Renal Registry, 2011)

    Institute of Scientific and Technical Information of China (English)

    张伟明; 钱家麒

    2012-01-01

    目的 通过上海市透析登记及其结果分析,反映上海市终末期肾病患者透析治疗的总体现状. 方法 上海市血液透析质量控制中心通过上海市“透析登记网络”系统, 将2010年1月1日到2010年12月31日接受到的全市60家医院登记资料(其中开展血液透析共60所医院63家血液透析室,开展腹膜透析共38家医院),对所登记的资料进行统计分析. 结果 2010年全年新增透析患者1621例(每百万人口发病率114.8pmp),较上一年度增加9.2%;其中血液透析占75.8%,腹膜透析占24.2%.2010年12月31日年末透析患者10 508例(每百万人口点治疗率744.0pmp),较上一年度增加14.6%;其中血液透析占80.6%,腹膜透析占19.4%.透析患者主要原发病因仍然是慢性肾小球肾炎(46.2%),新增透析患者中,糖尿病占第2位(19.5%).全年透析患者主要死亡原因依次为脑血管意外(22.4%)、感染(19.6%)和心血管事件(15.2%);年末透析患者中透析龄5年以上的占30.8%.患者透析充分性、贫血治疗状况、乙型肝炎和丙型肝炎病毒感染控制不断改善和提高.结论 上海市终末期肾脏病(ESRD)透析患者逐年增加,主要原发病因为肾小球肾炎,新增患者中,糖尿病患者逐年增加,血液透析仍是目前上海市ESRD患者主要透析治疗模式.%Objective This report is based on the data (up to December 31, 2010) from Shanghai Renal Registry Network. Our aim is to explore the current status of dialysis in Shanghai. Methods Data are collected from Shanghai Renal Registry Network in 2010. All of dialysis centers (n=63) in Shanghai enter the registry system. Results The incidence of new dialysis patients was 1621 (114.8 patients per million), of which 75.8% were on hemodiaiysis (HD) and 24.2% on peritoneal dialysis (PD). The point prevalence of dialysis patients on Dec 31, 2010 is 10 SOS (744.0 patients per million), of which 80.6% were on hemodiaiysis (HD) and 19

  18. [The Current State of Intercultural Opening in Psychosocial Services--The Results of an Assessment in an Inner-City District of Berlin].

    Science.gov (United States)

    Penka, Simone; Faißt, Hanna; Vardar, Azra; Borde, Theda; Mösko, Mike Oliver; Dingoyan, Demet; Schulz, Holger; Koch, Uwe; Kluge, Ulrike; Heinz, Andreas

    2015-09-01

    The need for intercultural opening of supply facilities for improving access and treatment of people with migration background is acknowledged in Germany. The purpose of the survey was to determine the current state of intercultural opening of psychosocial services in one Berlin district. 127 representatives of institutions were interviewed using a semi-structured assessment tool. The response rate was very high. The cross-cultural opening was implemented on a small scale. Staff as well as users with migration background were underrepresented. Varying and missing standardized documentation as well as problems in assessing users with migration background might be responsible for their low utilization rates. The use of professional interpreters was often not implemented. To judge the low level of implementation of cross-cultural opening in the psychosocial supply system in general, a review of responsible causes is required. © Georg Thieme Verlag KG Stuttgart · New York.

  19. First results from Acoustic Doppler Current Profiler measurements of meltwater flux in a large supraglacial river in western Greenland compared with downstream proglacial river outflow

    Science.gov (United States)

    Pitcher, L. H.; Smith, L. C.; Overstreet, B. T.; Chu, V. W.; Rennermalm, A. K.; Cooper, M. G.; Gleason, C. J.; Yang, K.

    2015-12-01

    A vast network of seasonally evolving, thermally eroding supraglacial rivers on the southwestern Greenland Ice Sheet (GrIS) is the preeminent transporter of meltwater across this area of the ablation zone. Supraglacial rivers are important for estimating surface water storage and transport into moulins and into the en-, sub-, and proglacial environments. Yet, little is known about their role in the GrIS cryo-hydrologic system. To that end, supraglacial river discharge in a large river, the "Rio Behar" (67.05°, -49.02°; ~75 km from the Kangerlussuaq International Airport), was measured in situ over 300 times: approximately four times per hour over three consecutive days from July 19 - 22, 2015. The Rio Behar drains a ~ 70 km2 ice catchment and enters a large moulin in the Watson River land-ice watershed in western Greenland. River discharge was measured using a Sontek M9 Acoustic Doppler Current Profiler. Each profile records water temperature, depth-integrated velocity, channel width and channel bathymetry. This novel dataset can be used to assess diurnal variations in river discharge, slope, velocity, stream power, and channel incision in order to enhance process-level understanding of GrIS meltwater routing, storage and transport. Future work will compare supraglacial river discharge in the Rio Behar with in situ estimates of proglacial river outflow upstream of the Watson River bridge in Kangerlussuaq, Greenland.

  20. The currently used commercial DNA-extraction methods give different results of clostridial and actinobacterial populations derived from human fecal samples.

    Science.gov (United States)

    Maukonen, Johanna; Simões, Catarina; Saarela, Maria

    2012-03-01

    Recently several human health-related microbiota studies have had partly contradictory results. As some differences may be explained by methodologies applied, we evaluated how different storage conditions and commonly used DNA-extraction kits affect bacterial composition, diversity, and numbers of human fecal microbiota. According to our results, the DNA-extraction did not affect the diversity, composition, or quantity of Bacteroides spp., whereas after a week's storage at -20 °C, the numbers of Bacteroides spp. were 1.6-2.5 log units lower (P bacteria, Eubacterium rectale (Erec)-group, Clostridium leptum group, bifidobacteria, and Atopobium group were 0.5-4 log units higher (P DNA-extraction as detected with qPCR, regardless of storage. Furthermore, the bacterial composition of Erec-group differed significantly after different DNA-extractions; after enzymatic DNA-extraction, the most prevalent genera detected were Roseburia (39% of clones) and Coprococcus (10%), whereas after mechanical DNA-extraction, the most prevalent genera were Blautia (30%), Coprococcus (13%), and Dorea (10%). According to our results, rigorous mechanical lysis enables detection of higher bacterial numbers and diversity from human fecal samples. As it was shown that the results of clostridial and actinobacterial populations are highly dependent on the DNA-extraction methods applied, the use of different DNA-extraction protocols may explain the contradictory results previously obtained. © 2011 Federation of European Microbiological Societies. Published by Blackwell Publishing Ltd. All rights reserved.

  1. Characterising the Actual Thermal Performance of Buildings: Current Results of Common Exercises Performed in the Framework of the IEA EBC Annex 58-Project

    DEFF Research Database (Denmark)

    Roels, Staf; Bacher, Peder; Bauwens, Geert

    2015-01-01

    Several studies have shown that actual thermal performance of buildings after construction may deviate significantly from that anticipated at design stage. As a result, there is growing interest in full scale testing of components and whole buildings. The IEA EBC Annex 58-project ‘Reliable Buildi...

  2. Current trends and outcomes of breast reconstruction following nipple-sparing mastectomy: results from a national multicentric registry with 1006 cases over a 6-year period.

    Science.gov (United States)

    Casella, Donato; Calabrese, Claudio; Orzalesi, Lorenzo; Gaggelli, Ilaria; Cecconi, Lorenzo; Santi, Caterina; Murgo, Roberto; Rinaldi, Stefano; Regolo, Lea; Amanti, Claudio; Roncella, Manuela; Serra, Margherita; Meneghini, Graziano; Bortolini, Massimiliano; Altomare, Vittorio; Cabula, Carlo; Catalano, Francesca; Cirilli, Alfredo; Caruso, Francesco; Lazzaretti, Maria Grazia; Meattini, Icro; Livi, Lorenzo; Cataliotti, Luigi; Bernini, Marco

    2017-05-01

    Reconstruction options following nipple-sparing mastectomy (NSM) are diverse and not yet investigated with level IA evidence. The analysis of surgical and oncological outcomes of NSM from the Italian National Registry shows its safety and wide acceptance both for prophylactic and therapeutic cases. A further in-depth analysis of the reconstructive approaches with their trend over time and their failures is the aim of this study. Data extraction from the National Database was performed restricting cases to the 2009-2014 period. Different reconstruction procedures were analyzed in terms of their distribution over time and with respect to specific indications. A 1-year minimum follow-up was conducted to assess reconstructive unsuccessful events. Univariate and multivariate analyses were performed to investigate the causes of both prosthetic and autologous failures. 913 patients, for a total of 1006 procedures, are included in the analysis. A prosthetic only reconstruction is accomplished in 92.2 % of cases, while pure autologous tissues are employed in 4.2 % and a hybrid (prosthetic plus autologous) in 3.6 %. Direct-to-implant (DTI) reaches 48.7 % of all reconstructions in the year 2014. Prophylactic NSMs have a DTI reconstruction in 35.6 % of cases and an autologous tissue flap in 12.9 % of cases. Failures are 2.7 % overall: 0 % in pure autologous flaps and 9.1 % in hybrid cases. Significant risk factors for failures are diabetes and the previous radiation therapy on the operated breast. Reconstruction following NSM is mostly prosthetic in Italy, with DTI gaining large acceptance over time. Failures are low and occurring in diabetic and irradiated patients at the multivariate analysis.

  3. Self-consistent kinetic simulations of lower hybrid drift instability resulting in electron current driven by fusion products in tokamak plasmas

    CERN Document Server

    Cook, J W S; Dendy, R O

    2010-01-01

    We present particle-in-cell (PIC) simulations of minority energetic protons in deuterium plasmas, which demonstrate a collective instability responsible for emission near the lower hybrid frequency and its harmonics. The simulations capture the lower hybrid drift instability in a regime relevant to tokamak fusion plasmas, and show further that the excited electromagnetic fields collectively and collisionlessly couple free energy from the protons to directed electron motion. This results in an asymmetric tail antiparallel to the magnetic field. We focus on obliquely propagating modes under conditions approximating the outer mid-plane edge in a large tokamak, through which there pass confined centrally born fusion products on banana orbits that have large radial excursions. A fully self-consistent electromagnetic relativistic PIC code representing all vector field quantities and particle velocities in three dimensions as functions of a single spatial dimension is used to model this situation, by evolving the in...

  4. Progress report on new results of the study of multi-planar and compact cylindrical wire arrays at 0.8-1.3 MA current at UNR Zebra generator

    Science.gov (United States)

    Kantsyrev, V. L.; Safronova, A. S.; Esaulov, A. A.; Presura, R.; Williamson, K. M.; Shrestha, I.; Ouart, N. D.; Yilmaz, M. F.; Wilcox, P. G.; Osborne, G. C.; Weller, M. E.; Shlyaptseva, V.; Rudakov, L. I.

    2008-11-01

    The studies that include the measurements of radiation yields, time-gated spectra and images, streak camera and laser probing images, spectral modeling, and magnetostatic and MHD simulations focus on Z-pinch plasma implosion and radiation features (including bright spots properties). The experiments with small size (3-10 mm) single-, double-, triple-, cross- planar, and compact cylindrical wire arrays from various materials at nominal as well as enhanced currents up to 1.3 MA were performed on the Zebra generator. The largest x-ray yields and powers were ranged for W and Mo. Observed multi-step precursor formation in multi-planar arrays may open new paths for radiation pulses shaping. Implosion and spectroscopic features specific for enhanced currents are discussed.

  5. CALCULATION AND EXPERIMENTAL ESTIMATION OF RESULTS OF ELECTRO-THERMAL ACTION OF RATIONED BY THE INTERNATIONAL STANDARD IEC 62305-1-2010 IMPULSE CURRENT OF SHORT BLOW OF ARTIFICIAL LIGHTNING ON THE THIN-WALLED COVERAGE FROM STAINLESS STEEL

    Directory of Open Access Journals (Sweden)

    M. I. Baranov

    2017-03-01

    Full Text Available Purpose. Calculation and experimental researches of electro-thermal resistibility of the pre-production thin-walled sheet models of outward roof of height technical buildings from stainless steel are easily soiled 12Х18Н10Т to direct action on them rationed by the International Standard IEC 62305-1-2010 aperiodic impulse of current of short bow of artificial lightning of temporal form 10/350 μs with the proper admittances on his peak-temporal parameters (PTP. Methodology. Electrophysics bases of technique of high voltage and large impulsive currents (LIC, and also scientific and technical bases of planning of high-voltage impulsive devices and measuring methods in them LIC with followings below extreme PTP: amplitude of impulse of current of ImL=200 кА (with admittance ±10 %; integral of action of impulse of current of JL=10·106 A2·s (with admittance ±35 %; %; duration of wavefront current of T1=10 μs (with admittance ±20 %; time, proper amplitude of impulse of current of ImL, tmL≤24 μs (with admittance ±20 %; duration of flowing of impulse of current of T2=350 μs (with admittance ±10 %. Results. The results of evaluation calculation and experimental researches of electro-thermal resistibility of the indicated pre-production sheet models are resulted measuring in the plan of 0,5 x 0,5 m from stainless steel are easily soiled the 12Х18Н10Т thickness of 1 mm to action on them of aperiodic impulse of current of short blow of artificial lightning with rationed PTP on the requirements of the International Standard IEC 62305-1-2010. In high current experiments amplitude of ImL of the aperiodic rationed impulse of current of artificial lightning of temporal form of T1/T2=15 μs/315 μs changed in the range of (100-184 кА. The integral of action of JL of impulse of current for I-IV of levels of protection of lightning of technical objects (TO numeral made from 2,32·106 А2·s to 7,88·106 А2·s, and the flowing through the

  6. Stability analysis of direct current control in current source rectifier

    DEFF Research Database (Denmark)

    Lu, Dapeng; Wang, Xiongfei; Blaabjerg, Frede

    2017-01-01

    Current source rectifier with high switching frequency has a great potential for improving the power efficiency and power density in ac-dc power conversion. This paper analyzes the stability of direct current control based on the time delay effect. Small signal model including dynamic behaviors...... of dc link is developed to identify the control plants of grid ac current control and dc current control. Analysis on the poles and zeros under dq frame is carried out. Base on this model, it turns out that the phase lag caused by the time delay can stabilized the grid ac current control while reduces...... the stable region for dc current control. Simulation and experimental results are presented to validate the theoretical analysis....

  7. TOKAMAK EQUILIBRIA WITH CENTRAL CURRENT HOLES AND NEGATIVE CURRENT DRIVE

    Energy Technology Data Exchange (ETDEWEB)

    CHU, M.S.; PARKS, P.B.

    2002-06-01

    OAK B202 TOKAMAK EQUILIBRIA WITH CENTRAL CURRENT HOLES AND NEGATIVE CURRENT DRIVE. Several tokamak experiments have reported the development of a central region with vanishing currents (the current hole). Straightforward application of results from the work of Greene, Johnson and Weimer [Phys. Fluids, 3, 67 (1971)] on tokamak equilibrium to these plasmas leads to apparent singularities in several physical quantities including the Shafranov shift and casts doubts on the existence of this type of equilibria. In this paper, the above quoted equilibrium theory is re-examined and extended to include equilibria with a current hole. It is shown that singularities can be circumvented and that equilibria with a central current hole do satisfy the magnetohydrodynamic equilibrium condition with regular behavior for all the physical quantities and do not lead to infinitely large Shafranov shifts. Isolated equilibria with negative current in the central region could exist. But equilibria with negative currents in general do not have neighboring equilibria and thus cannot have experimental realization, i.e. no negative currents can be driven in the central region.

  8. Update of the BIPM comparison BIPM.RI(II)-K1.Sn-113 of activity measurements of the radionuclide 113Sn to include the 2010 results of the PTB (Germany) and the LNE-LNHB (France), and the 2011 result of the CIEMAT (Spain)

    Science.gov (United States)

    Michotte, C.; Ratel, G.; Courte, S.; Kossert, K.; Nähle, O.; Bobin, C.; Lépy, M.-C.; Moune, M.; Garcia-Toraño, E.; Peyres, V.; Roteta, M.

    2016-01-01

    Since 1975, seven national metrology institutes (NMI) have submitted eleven samples of known activity of 113Sn to the International Reference System (SIR) for activity comparison at the Bureau International des Poids et Mesures (BIPM), with comparison identifier BIPM.RI(II)-K1.Sn-113. The values of the activity submitted were between about 0.7 MBq and 22 MBq. The present primary standardization results for the PTB, Germany and the LNE-LNHB, France, replace their earlier results of 1989 and 1992, respectively. A key comparison reference value (KCRV) has been evaluated for the first time for 113Sn. There are only three results remaining in the BIPM.RI(II)-K1.Sn-113 comparison, all the previously published ones being outdated. The degrees of equivalence between each of these three equivalent activities measured in the SIR and the KCRV have been calculated and the results are given in the form of a table. A graphical presentation is also given. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCRI, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

  9. Current ornithology

    CERN Document Server

    1983-01-01

    The appearance of the first volume of a projected series is the occasion for comment on scope, aims, and genesis of the work. The scope of Current Ornithology is all of the biology of birds. Ornithology, as a whole-organism science, is concerned with birds at every level of bi­ ological organization, from the molecular to the community, at least from the Jurassic to the present time, and over every scholarly discipline in which bird biology is done; to say this is merely to expand a dic­ tionary definition of "ornithology. " The aim of the work, to be realized over several volumes, is to present reviews or position statements con­ cerning the active fields of ornithological research. The reviews will be relatively short, and often will be done from the viewpoint of a readily­ identified group or school. Such a work could have come into being at any time within the past fifty years, but that Current Ornithology appears now is a result of events that are only seven to eight years old. One important event wa...

  10. Spin current

    CERN Document Server

    Valenzuela, Sergio O; Saitoh, Eiji; Kimura, Takashi

    2012-01-01

    In a new branch of physics and technology called spin-electronics or spintronics, the flow of electrical charge (usual current) as well as the flow of electron spin, the so-called 'spin current', are manipulated and controlled together. This book provides an introduction and guide to the new physics and application of spin current.

  11. Including Magnetostriction in Micromagnetic Models

    Science.gov (United States)

    Conbhuí, Pádraig Ó.; Williams, Wyn; Fabian, Karl; Nagy, Lesleis

    2016-04-01

    The magnetic anomalies that identify crustal spreading are predominantly recorded by basalts formed at the mid-ocean ridges, whose magnetic signals are dominated by iron-titanium-oxides (Fe3-xTixO4), so called "titanomagnetites", of which the Fe2.4Ti0.6O4 (TM60) phase is the most common. With sufficient quantities of titanium present, these minerals exhibit strong magnetostriction. To date, models of these grains in the pseudo-single domain (PSD) range have failed to accurately account for this effect. In particular, a popular analytic treatment provided by Kittel (1949) for describing the magnetostrictive energy as an effective increase of the anisotropy constant can produce unphysical strains for non-uniform magnetizations. I will present a rigorous approach based on work by Brown (1966) and by Kroner (1958) for including magnetostriction in micromagnetic codes which is suitable for modelling hysteresis loops and finding remanent states in the PSD regime. Preliminary results suggest the more rigorously defined micromagnetic models exhibit higher coercivities and extended single domain ranges when compared to more simplistic approaches.

  12. Reply to "Comment on 'A Self-Consistent Model of the Interacting Ring Current Ions and Electromagnetic Ion Cyclotron Waves, Initial Results: Waves and Precipitation Fluxes' and 'Self-Consistent Model of the Magnetospheric Ring Current and Propagating Electromagnetic Ion Cyclotron Waves: Waves in Multi-Ion Magnetosphere' by Khazanov et al. et al."

    Science.gov (United States)

    Khazanov, G. V.; Gamayunov, K. V.; Gallagher, D. L.; Kozyra, J. W.

    2007-01-01

    It is well-known that the effects of electromagnetic ion cyclotron (EMIC) waves on ring current (RC) ion and radiation belt (RB) electron dynamics strongly depend on such particle/wave characteristics as the phase-space distribution function, frequency, wavenormal angle, wave energy, and the form of wave spectral energy density. The consequence is that accurate modeling of EMIC waves and RC particles requires robust inclusion of the interdependent dynamics of wave growth/damping, wave propagation, and[ particles. Such a self-consistent model is being progressively developed by Khazanov et al. [2002, 2006, 2007]. This model is based on a system of coupled kinetic equations for the RC and EMIC wave power spectral density along with the ray tracing equations. Thome and Home [2007] (hereafter referred to as TH2007) call the Khazanov et al. [2002, 2006] results into question in their Comment. The points in contention can be summarized as follows. TH2007 claim that: (1) "the important damping of waves by thermal heavy ions is completely ignored", and Landau damping during resonant interaction with thermal electrons is not included in our model; (2) EMIC wave damping due to RC O + is not included in our simulation; (3) non-linear processes limiting EMIC wave amplitude are not included in our model; (4) growth of the background fluctuations to a physically significantamplitude"must occur during a single transit of the unstable region" with subsequent damping below bi-ion latitudes,and consequently"the bounce averaged wave kinetic equation employed in the code contains a physically erroneous 'assumption". Our reply will address each of these points as well as other criticisms mentioned in the Comment. TH2007 are focused on two of our papers that are separated by four years. Significant progress in the self-consistent treatment of the RC-EMIC wave system has been achieved during those years. The paper by Khazanov et al. [2006] presents the latest version of our model, and in

  13. Magnetic current sensor

    Science.gov (United States)

    Black, Jr., William C. (Inventor); Hermann, Theodore M. (Inventor)

    1998-01-01

    A current determiner having an output at which representations of input currents are provided having an input conductor for the input current and a current sensor supported on a substrate electrically isolated from one another but with the sensor positioned in the magnetic fields arising about the input conductor due to any input currents. The sensor extends along the substrate in a direction primarily perpendicular to the extent of the input conductor and is formed of at least a pair of thin-film ferromagnetic layers separated by a non-magnetic conductive layer. The sensor can be electrically connected to a electronic circuitry formed in the substrate including a nonlinearity adaptation circuit to provide representations of the input currents of increased accuracy despite nonlinearities in the current sensor, and can include further current sensors in bridge circuits.

  14. Including social impacts in LCIA

    DEFF Research Database (Denmark)

    Dreyer, Louise Camilla; Hauschild, Michael Zwicky

    2004-01-01

    environmental impacts and, therefore, recommendations based on LCA fail to address both social and economic concerns. This has raised questions about LCA's ability to support sustainable development decisions. In a research project carried out at Brødrene Hartmann A/S and the Technical University of Denmark...... a framework for social LCA is currently being developed. The project quantifies social impacts and makes them operational in the traditional LCIA framework by developing measurable indicators. These indicators are selected to provide a meaningful and sufficient overall description of social impacts of all...

  15. Current limiters

    Energy Technology Data Exchange (ETDEWEB)

    Loescher, D.H. [Sandia National Labs., Albuquerque, NM (United States). Systems Surety Assessment Dept.; Noren, K. [Univ. of Idaho, Moscow, ID (United States). Dept. of Electrical Engineering

    1996-09-01

    The current that flows between the electrical test equipment and the nuclear explosive must be limited to safe levels during electrical tests conducted on nuclear explosives at the DOE Pantex facility. The safest way to limit the current is to use batteries that can provide only acceptably low current into a short circuit; unfortunately this is not always possible. When it is not possible, current limiters, along with other design features, are used to limit the current. Three types of current limiters, the fuse blower, the resistor limiter, and the MOSFET-pass-transistor limiters, are used extensively in Pantex test equipment. Detailed failure mode and effects analyses were conducted on these limiters. Two other types of limiters were also analyzed. It was found that there is no best type of limiter that should be used in all applications. The fuse blower has advantages when many circuits must be monitored, a low insertion voltage drop is important, and size and weight must be kept low. However, this limiter has many failure modes that can lead to the loss of over current protection. The resistor limiter is simple and inexpensive, but is normally usable only on circuits for which the nominal current is less than a few tens of milliamperes. The MOSFET limiter can be used on high current circuits, but it has a number of single point failure modes that can lead to a loss of protective action. Because bad component placement or poor wire routing can defeat any limiter, placement and routing must be designed carefully and documented thoroughly.

  16. RESULTS OF TESTS OF LIGHTNING-RODS WITH UNIVERSAL CLAMPS BY THE APERIODIC IMPULSES OF CURRENT OF ARTIFICIAL LIGHTNING WITH THE PEAK-TEMPORAL PARAMETERS RATIONED ON FOREIGN STANDARDS

    Directory of Open Access Journals (Sweden)

    M.I. Baranov

    2015-06-01

    Full Text Available Purpose. Test in obedience to the requirements of row of operating foreign standards of round metallic lightning-rods with the flat metallic universal clamps of the special type on firmness to direct action of аperiodic impulses of current of temporal form 10/350 μs by amplitude of 50 кА (N− class and 100 кА (H− class. Methodology. The order of leadthrough of these tests is certain the followings normative documents: International IEC 62305-1: 2010, Russian national GOST R IEC 62305-1-2010 and German national DIN EN 50164-1:2008 Standards. Results. Conducted on a powerful high-voltage pulsed current of artificial linear lightning with the peak-temporal parameters and admittances of test rationed on the indicated foreign standards rationed that all of the lightning-rods tested in collection with universal clamps, isolating holders and ceramic elements of roof of technical building were survive electrodynamics and electrothermal action of in-use single short blow of an artificial storm digit. Originality. First in domestic practice the similar model tests of lightning-rods are conducted with universal clamps, executed from different explorer materials, on firmness to flowing to on by it the indicated large impulsive currents of artificial lightning. Practical value. Real firmness to lightning of round copper and zincked steel lightning-rods is certain with the flat copper, zincked steel and non-rusting steel universal clamps of the special execution.

  17. Including social impacts in LCIA

    DEFF Research Database (Denmark)

    Dreyer, Louise Camilla; Hauschild, Michael Zwicky; Schierbeck, Jens

    2004-01-01

    environmental impacts and, therefore, recommendations based on LCA fail to address both social and economic concerns. This has raised questions about LCA's ability to support sustainable development decisions. In a research project carried out at Brødrene Hartmann A/S and the Technical University of Denmark......Sustainability management in industries is often defined by measuring the performance against the trippel bottom-line, People, Planet and Profit in business decisions. The product chain perspective inherent in LCA is very suitable for sustainability management but LCA methodology only considers...... a frameowork for social LCA is currently being developed. The project quantifies social impacts and makes them operational in the traditional LCIA framework by developing measureable indicators. These indicators are selected to provide a meaningful and sufficient overall description of social impacts of all...

  18. Decomposition of residue currents

    OpenAIRE

    Andersson, Mats; Wulcan, Elizabeth

    2007-01-01

    Given a submodule $J\\subset \\mathcal O_0^{\\oplus r}$ and a free resolution of $J$ one can define a certain vector valued residue current whose annihilator is $J$. We make a decomposition of the current with respect to Ass$(J)$ that correspond to a primary decomposition of $J$. As a tool we introduce a class of currents that includes usual residue and principal value currents; in particular these currents admit a certain type of restriction to analytic varieties and more generally to construct...

  19. Non-inductive current drive

    NARCIS (Netherlands)

    Westerhof, E.

    2012-01-01

    This lecture addresses the various ways of non-inductive current generation. In particular, the topics covered include the bootstrap current, RF current drive, neutral beam current drive, alternative methods, and possible synergies between different ways of non-inductive current generation.

  20. NON-INDUCTIVE CURRENT DRIVE

    NARCIS (Netherlands)

    Westerhof, E.

    2010-01-01

    This lecture addresses the various ways of non-inductive current generation. In particular, the topics covered include the bootstrap current, RF current drive, neutral beam current drive, alternative methods, and possible synergies between different ways of non-inductive current generation.

  1. Uncertainty of Voltage Measurement Results of Leakage Current Tester%泄漏电流测试仪试验电压测量结果的不确定度评估

    Institute of Scientific and Technical Information of China (English)

    王霞

    2012-01-01

    介绍了泄漏电流测试仪试验电压测量结果的不确定度评估,详细分析了影响测量不确定度的原因,计算了各不确定度分量并给出合成标准不确定度。为校准结果的准确性提供了可靠保证。%The uncertainty of voltage measurement results of leakage current tester is roduced in this paper. The paper analyzes the reasons that affects the uncertainty of measurement, calculates the every kind of uncertainty components and gives the combined standard uncertainty. This work assures the accuracy of calibration result.

  2. FLUXNET2015 Dataset: Batteries included

    Science.gov (United States)

    Pastorello, G.; Papale, D.; Agarwal, D.; Trotta, C.; Chu, H.; Canfora, E.; Torn, M. S.; Baldocchi, D. D.

    2016-12-01

    The synthesis datasets have become one of the signature products of the FLUXNET global network. They are composed from contributions of individual site teams to regional networks, being then compiled into uniform data products - now used in a wide variety of research efforts: from plant-scale microbiology to global-scale climate change. The FLUXNET Marconi Dataset in 2000 was the first in the series, followed by the FLUXNET LaThuile Dataset in 2007, with significant additions of data products and coverage, solidifying the adoption of the datasets as a research tool. The FLUXNET2015 Dataset counts with another round of substantial improvements, including extended quality control processes and checks, use of downscaled reanalysis data for filling long gaps in micrometeorological variables, multiple methods for USTAR threshold estimation and flux partitioning, and uncertainty estimates - all of which accompanied by auxiliary flags. This "batteries included" approach provides a lot of information for someone who wants to explore the data (and the processing methods) in detail. This inevitably leads to a large number of data variables. Although dealing with all these variables might seem overwhelming at first, especially to someone looking at eddy covariance data for the first time, there is method to our madness. In this work we describe the data products and variables that are part of the FLUXNET2015 Dataset, and the rationale behind the organization of the dataset, covering the simplified version (labeled SUBSET), the complete version (labeled FULLSET), and the auxiliary products in the dataset.

  3. Remote field eddy current testing

    Energy Technology Data Exchange (ETDEWEB)

    Cheong, Y. M.; Jung, H. K.; Huh, H.; Lee, Y. S.; Shim, C. M

    2001-03-01

    The state-of-art technology of the remote field eddy current, which is actively developed as an electromagnetic non-destructive testing tool for ferromagnetic tubes, is described. The historical background and recent R and D activities of remote-field eddy current technology are explained including the theoretical development of remote field eddy current, such as analytical and numerical approach, and the results of finite element analysis. The influencing factors for actual applications, such as the effect of frequency, magnetic permeability, receiving sensitivity, and difficulties of detection and classification of defects are also described. Finally, two examples of actual application, 1) the gap measurement between pressure tubes and calandria tube in CANDU reactor and, 2) the detection of defects in the ferromagnetic heat exchanger tubes, are described. The future research efforts are also included.

  4. The criterion for blanking-off heat-transfer tubes in the steam generators at VVER-based nuclear power plants based on the results of eddy-current examination

    Science.gov (United States)

    Lunin, V. P.; Zhdanov, A. G.; Chegodaev, V. V.; Stolyarov, A. A.

    2015-05-01

    The problem of defining the criterion for blanking off heat-transfer tubes in the steam generators at nuclear power plants on the basis of signals obtained from the standard multifrequency eddy-current examination is considered. The decision about blanking off one or another tube is presently made with reference to one parameter of the relevant signal at the working frequency, namely, with reference to its phase, which directly depends on the depth of the flaw being detected, i.e., a crack in the tube. The crack depth equal to 60% of the tube wall thickness is regarded to be the critical one, at which a decision about withdrawing such a tube out from operation (blanking off) must be taken. However, since mechanical tensile rupture tests of heat-transfer tubes show the possibility of their further use with such flaws, the secondary parameter of the signal, namely, its amplitude, must be used for determining the blanking-off criterion. The signals produced by the standard flow-type transducers in response to flaws in the form of a longitudinal crack having the depth and length within the limits permitted by the relevant regulations were calculated using 3D finite-element modeling. Based on the obtained results, the values of the eddy-current signal amplitude were determined, which, together with the signal phase value, form a new amplitude-phase criterion for blanking off heat-transfer tubes. For confirming the effectiveness of this technique, the algorithm for revealing the signal indications satisfying the proposed amplitude-phase criterion was tested on real signals obtained from operational eddy-current examination of the state of steam generator heat-transfer tubes carried out within the framework of planned preventive repair.

  5. Prognosis - Cancer Currents Blog

    Science.gov (United States)

    A catalog of posts from NCI’s Cancer Currents blog on research related to cancer prognosis. Includes posts on factors that influence prognosis, prognostic biomarkers, and doctor-patient communications about prognosis.

  6. AUTO FIB Current Status

    Science.gov (United States)

    Parry, I.; Sharples, R. M.

    The current status of the automated fibre positioner, Autofib, is reviewed including the positioning performance and the set-up speed. Future plans to build another Autofib for the 4.2 m William Herschel Telescope are also briefly discussed.

  7. 中国ST段抬高急性冠状动脉综合征诊疗现况调查%Current clinical practice patterns and outcome for acute coronary syndromes in China: results of BRIG project

    Institute of Scientific and Technical Information of China (English)

    刘群; 赵冬; 刘军; 王薇; 刘静; 代表中国冠心病二级预防架桥工程研究协作组

    2009-01-01

    Objective To analyze current clinical management patterns and outcome of inpatients with ST segment elevation acute coronary syndromes (ACS) in China. Methods Totally 1304 in-patients with ST segment elevation ACS from 64 hospitals across China were recruited and a standard questionnaire was used to get information of the patients including demographic, treatments and in-hospital outcomes. Results (1) There were no significant differences in baseline characteristics between the patients from tertiary hospitals and that from the secondary hospitals. (2) Reperfusion therapy was applied more often in tertiary hospitals (57.9%) than in secondary hospitals (42.3%). Thrombolysis was more often used in secondary hospitals than that in tertiary hospitals (37.4% vs. 14.5%). The median time from pain onset to hospital was 240 min, the median time from admission to reperfusion was 60 min for thromhalysis and 110 min for PCI. (3) Statias and glycoprotein Ⅱb/Ⅲa antagonists were given more frequently in tertiary hospitals. (4) Major in-hospital events and death rates were significantly higher in secondary hospitals than in tertiary hospitals. Multivariate logistic regression analysis showed that age ≥ 75 years, hypertension, diabetes, reperfusion, aspirin, β-blocker and ACE/ARB inhibitor use were associated independently with in-hospital mortality. Conclusions There is a big gap between guidelines and current management of ST segment elevation ACS in China, especially in secondary hospitals.%目的 了解目前我国ST段抬高急性冠状动脉综合征(ACS)临床治疗及二级预防措施的实施状况.方法 在中国31个省市自治区选择33家三级医院和32家二级医院,每家医院选择住院患者50例,共计3323例,其中1304例(39.2%)为ST段抬高的ACS.采用问卷回顾形式收集住院患者临床治疗及二级预防信息.结果 (1)三级医院在人员及设备方面均优于二级医院,仅33.3%的二级医院拥有心脏导管检查设备;

  8. Recent developments in superconducting materials including ceramics

    Energy Technology Data Exchange (ETDEWEB)

    Tachikawa, Kyoji

    1987-06-01

    This report describes the history of superconduction starting in 1911, when the superconducting phenomenon was first observed in murcury, until the recent discovery of superconducting materials with high critical temperatures. After outlining the BCS theory, basic characteristics are discussed including the critical temperature, magnetic field and current density to be reached for realizing the superconducting state. Various techniques for practical superconducting materials are discussed, including methods for producing extra fine multiconductor wires from such superconducting alloys as Nb-Ti, intermetallic Nb/sub 3/Sn compound and V/sub 3/Ga, as well as methods for producing wires of Nb/sub 3/Al, Nb/sub 3/(Al, Ge) and Nb/sub 3/Ge such as continuous melt quenching, electron beam irradiation, laser beam irradiation and chemical evaporation. Characteristics of superconducting ceramics are described, along with their applications including superconducting magnets and superconducting elements. (15 figs, 1 tab, 19 refs)

  9. Current Titles

    Energy Technology Data Exchange (ETDEWEB)

    Various

    2006-06-01

    This booklet is published for those interested in current research being conducted at the National Center for Electron Microscopy. The NCEM is a DOE-designated national user facility and is available at no charge to qualified researchers. Access is controlled by an external steering committee. Interested researchers may contact Jane Cavlina, Administrator, at 510/486-6036.

  10. FY2000 report of the research results of medical/engineering cooperative research project, basic research on systems for minimally invasive diagnostic/treatment of circulatory system diseases, including prognostic diagnosis; 2000 nendo igaku kogaku renkeigata kenkyu jigyo, junkankikei shikkan ni taisuru yogo shindan wo fukumu teishinshu shindan chiryo system ni kansuru kiso kenkyu seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    The basic researches on minimally invasive diagnostic/treatment systems are conducted for circulatory system diseases, and the FY 2000 results are reported. The program for developing the heart surgery supporting manipulator includes development of the manipulator of 7 degree of freedom and fail-safe mechanisms to be incorporated in the patient-side system, and research and development of the heart motion compensation type robot system. The program for developing the diagnosis/treatment system aided by intravascular optical analysis includes development of intravascular endoscopy by the aid of LED emitting blue color of high brightness, and automatic analyzer for the in vivo vascular endothelial cell functions. The program for the minimally invasive diagnostic system includes development of superimposing system for integrating the images by the NOGA system and cine-coronary angiography. The other R and D items include artificial vascular systems to be put in the blood vessels, adhesives for a living body, suture instruments for fine blood vessels, heart surgery supporting system, based on the infrared spectroscopy, endoscopic system for the cranical bones, arterialization method, and gene-aided treatment. (NEDO)

  11. Including Indigenous Minorities in Decision-Making

    DEFF Research Database (Denmark)

    Pristed Nielsen, Helene

    Based on theories of public sphere participation and deliberative democracy, this book presents empirical results from a study of experiences with including Aboriginal and Maori groups in political decision-making in respectively Western Australia and New Zealand......Based on theories of public sphere participation and deliberative democracy, this book presents empirical results from a study of experiences with including Aboriginal and Maori groups in political decision-making in respectively Western Australia and New Zealand...

  12. Low current beam techniques

    Energy Technology Data Exchange (ETDEWEB)

    Saint, A.; Laird, J.S.; Bardos, R.A.; Legge, G.J.F. [Melbourne Univ., Parkville, VIC (Australia). School of Physics; Nishijima, T.; Sekiguchi, H. [Electrotechnical Laboratory, Tsukuba (Japan).

    1993-12-31

    Since the development of Scanning Transmission Microscopy (STIM) imaging in 1983 many low current beam techniques have been developed for the scanning (ion) microprobe. These include STIM tomography, Ion Beam Induced Current, Ion Beam Micromachining and Microlithography and Ionoluminense. Most of these techniques utilise beam currents of 10{sup -15} A down to single ions controlled by beam switching techniques This paper will discuss some of the low beam current techniques mentioned above, and indicate, some of their recent applications at MARC. A new STIM technique will be introduced that can be used to obtain Z-contrast with STIM resolution. 4 refs., 3 figs.

  13. Inrush Current Control Circuit

    Science.gov (United States)

    Cole, Steven W. (Inventor)

    2002-01-01

    An inrush current control circuit having an input terminal connected to a DC power supply and an output terminal connected to a load capacitor limits the inrush current that charges up the load capacitor during power up of a system. When the DC power supply applies a DC voltage to the input terminal, the inrush current control circuit produces a voltage ramp at the load capacitor instead of an abrupt DC voltage. The voltage ramp results in a constant low level current to charge up the load capacitor, greatly reducing the current drain on the DC power supply.

  14. Bootstrap Current in Spherical Tokamaks

    Institute of Scientific and Technical Information of China (English)

    王中天; 王龙

    2003-01-01

    Variational principle for the neoclassical theory has been developed by including amomentum restoring term in the electron-electron collisional operator, which gives an additionalfree parameter maximizing the heat production rate. All transport coefficients are obtained in-cluding the bootstrap current. The essential feature of the study is that the aspect ratio affects thefunction of the electron-electron collision operator through a geometrical factor. When the aspectratio approaches to unity, the fraction of circulating particles goes to zero and the contribution toparticle flux from the electron-electron collision vanishes. The resulting diffusion coefficient is inrough agreement with Hazeltine. When the aspect ratio approaches to infinity, the results are inagreement with Rosenbluth. The formalism gives the two extreme cases a connection. The theoryis particularly important for the calculation of bootstrap current in spherical tokamaks and thepresent tokamaks, in which the square root of the inverse aspect ratio, in general, is not small.

  15. Current and Current Fluctuations in Quantum Shuttles

    DEFF Research Database (Denmark)

    Jauho, Antti-Pekka; Flindt, Christian; Novotny, Tomas

    2005-01-01

    theoretical tools needed for the analysis, e.g., generalized master equations and Wigner functions, and we outline the methods how the resulting large numerical problems can be handled. Illustrative results are given for current, noise, and full counting statistics for a number of model systems. Throughout...

  16. Current major depressive syndrome measured with the Patient Health Questionnaire-9 (PHQ-9) and the Composite International Diagnostic Interview (CIDI): results from a cross-sectional population-based study of adults in Germany.

    Science.gov (United States)

    Maske, Ulrike E; Busch, Markus A; Jacobi, Frank; Beesdo-Baum, Katja; Seiffert, Ingeburg; Wittchen, Hans-Ulrich; Riedel-Heller, Steffi; Hapke, Ulfert

    2015-04-10

    Prevalence estimates for depression vary considerably by the type of assessment instrument, and there is limited information on their overlap in population-based samples. Our aim was to compare the Patient Health Questionnaire-9 (PHQ-9) with the Composite International Diagnostic Interview (CIDI) as measures for current major depressive syndrome (MDS) in a large population-based sample. Data derived from the mental health module of the nationwide cross-sectional German Health Interview and Examination Survey for Adults (DEGS1-MH) (n = 4483; age 18-79 years). MDS in the past two weeks was assessed (a) using the PHQ-9 diagnostic algorithm (PHQ-MDS) and (b) based on CIDI information about the latest symptom occurrence (recency) (CIDI-MDS). Prevalences, overall concordance and percentages of overlap of both MDS measures were determined. Prevalences of affirmed PHQ-9 depression symptoms and the mean and median PHQ-9 sum scores were analyzed per measure. Prevalence of current MDS was 2.7% (95% CI: 2.0-3.6) for PHQ-MDS and 3.9% (95% CI: 3.1-5.0) for CIDI-MDS. The overall agreement between both measures was moderate (kappa: 0.43). Of all the participants, 1.5% (95% CI: 1.0-2.2) were classified as MDS cases by both measures, with 54.5% (95% CI: 42.7-65.9) of PHQ-MDS cases and 37.9% (95% CI: 27.8-49.1) of CIDI-MDS cases also being classified as MDS by the respective other MDS measure. However, 94.8% (95% CI: 93.6-95.8) of the participants were classified as non-MDS by both measures, with 97.5% (95% CI: 96.6-98.1) of non-PHQ-MDS and 98.7% (95% CI: 98.2-99.1) of non-CIDI-MDS being classified as non-MDS by the respective other MDS measure. The mean and median PHQ-9 sum score was higher in those with PHQ-MDS than in those with CIDI-MDS. Both measures have a high level of agreement for ruling out current MDS, but the overlap in their classification of cases is moderate. Our results indicate that they cannot be interpreted as equal measures of the same construct, suggesting

  17. Current titles

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-07-01

    This booklet is published for those interested in current research being conducted at the National Center for Electron Microscopy. The NCEM is a DOE-designated national user facility and is available at no charge to qualified researchers. Access is controlled by an external steering committee. Interested researchers may contact Gretchen Hermes at (510) 486-5006 or address below for a User`s Guide. Copies of available papers can be ordered from: Theda Crawford National Center for Electron Microscopy, Lawrence Berkeley Laboratory, One Cyclotron Rd., MS72, Berkeley, California, USA 94720.

  18. Application of fault current limiters

    Energy Technology Data Exchange (ETDEWEB)

    Neumann, A.

    2007-11-30

    This report presents the results of a study commissioned by the Department for Business, Enterprise and Industry (BERR; formerly the Department of Trade and Industry) into the application of fault current limiters in the UK. The study reviewed the current state of fault current limiter (FCL) technology and regulatory position in relation to all types of current limiters. It identified significant research and development work with respect to medium voltage FCLs and a move to high voltage. Appropriate FCL technologies being developed include: solid state breakers; superconducting FCLs (including superconducting transformers); magnetic FCLs; and active network controllers. Commercialisation of these products depends on successful field tests and experience, plus material development in the case of high temperature superconducting FCL technologies. The report describes FCL techniques, the current state of FCL technologies, practical applications and future outlook for FCL technologies, distribution fault level analysis and an outline methodology for assessing the materiality of the fault level problem. A roadmap is presented that provides an 'action agenda' to advance the fault level issues associated with low carbon networks.

  19. Theme: Staying Current--Horticulture.

    Science.gov (United States)

    Shry, Carroll L., Jr.; And Others

    1986-01-01

    This theme issue on staying current in horticulture includes articles on sex equity in horticulture, Future Farmers of America, career opportunities in horticulture, staying current with your school district's needs, staying current in horticulture instruction, staying current with landscape trade associations, emphasizing the basics in vocational…

  20. Generalized fluid theory including non-Maxwellian kinetic effects

    OpenAIRE

    Izacard, Olivier

    2016-01-01

    The results obtained by the plasma physics community for the validation and the prediction of turbulence and transport in magnetized plasma come mainly from the use of very CPU-consuming particle-in-cell or (gyro)kinetic codes which naturally include non-Maxwellian kinetic effects. To date, fluid codes are not considered to be relevant for the description of these kinetic effects. Here, after revisiting the limitations of the current fluid theory developed in the 19th century, we generalize t...

  1. Current state of peatland soils as an effect of long-term drainage – preliminary results of peatland ecosystems investigation in the Grójecka Valley (central Poland

    Directory of Open Access Journals (Sweden)

    Glina Bartłomiej

    2016-03-01

    Full Text Available Understanding the effect of long-term drainage of peatland areas is helpful in future peatland management and regulations of water conditions. The aim of this work was to assess the current state of fen peatland soils in the Grójecka Valley (eastern part of the Wielkopolskie voivodeship, central Poland, affected by long-term agricultural use (pastures, meadows since the 1960s and potentially by lignite open pit mining industry (KWB Konin since 1980s. Field studies were carried out in 2015 in selected fen peatland areas. Soil material for laboratory analysis was collected from genetic horizons from four soil profiles. The surface horizons of studied organic and organo-mineral soils were built with well-developed moorsh material. They were classified as medium moorshiefied – MtII (profile 1, 3 and 4 and strongly moorshiefied – MtIII (profile 2. Obtained results of physical and physico-chemical analysis indicate that long-term peatland utilization connected with potential impact of the lignite mining, transformed mainly the upper horizons of studied organic and organo-mineral soils. However, despite obvious strong human impact on peatlands ecosystems, we cannot exclude the climate variables, what should be confirmed by long-term monitoring program. Furthermore, presented paper indicated that new subtype moorsh-muddy soils (in Polish: gleby murszowo-mułowe within the type of gleyic soils should be implemented in the next version of Polish Soil Classification.

  2. Stressful life events and current psychological distress are associated with self-reported hypertension but not with true hypertension: results from a cross-sectional population-based study

    Directory of Open Access Journals (Sweden)

    Fuchs Flávio D

    2008-10-01

    Full Text Available Abstract Background The evidence linking stress to hypertension has been scarcely documented in population-based studies. Methods Participants were selected through a multi-stage probability sampling and interviewed at home, being submitted to measures of demographics, anthropometrics, blood pressure (BP, and risk factors for hypertension. Hypertension was defined as BP ≥ 140/90 mm Hg or use of BP-lowering drugs or as self-reported hypertension. Stressful life events were investigated through an inventory of nine major life events occurring in the year preceding the interview. Psychological distress was evaluated through a facial scale of expression of emotion in the last month. Results In the total, 1,484 adult individuals were investigated. Prevalence of hypertension was lower in individuals who reported any stressful life event in comparison with individuals who did not reported an event (34.3 versus 44.2%, P Conclusion Recent stressful life events and current psychological distress are not associated with hypertension. Associations between stress events and distress with self-reported hypertension are not intermediated by effects of stress on blood pressure, and may be ascribed to negative feeling about disease and not to the disease itself.

  3. A quantitative definition of hypervalencyElectronic supplementary information (ESI) available: Full data for charge calculations on the test set of molecules; original data for Fig. 1-3, including geometries, energies and QTAIM charges; geometries and QTAIM charges for all other species; worked examples of γ calculations; results for alternative charge models. See DOI: 10.1039/c5sc02076j

    National Research Council Canada - National Science Library

    Durrant, Marcus C

    2015-01-01

    From the inception of Lewis' theory of chemical bonding, hypervalency has remained a point of difficulty that has not been fully resolved by the currently accepted qualitative definition of this term...

  4. Maximum-entropy closure of hydrodynamic moment hierarchies including correlations.

    Science.gov (United States)

    Hughes, Keith H; Burghardt, Irene

    2012-06-07

    Generalized hydrodynamic moment hierarchies are derived which explicitly include nonequilibrium two-particle and higher-order correlations. The approach is adapted to strongly correlated media and nonequilibrium processes on short time scales which necessitate an explicit treatment of time-evolving correlations. Closure conditions for the extended moment hierarchies are formulated by a maximum-entropy approach, generalizing related closure procedures for kinetic equations. A self-consistent set of nonperturbative dynamical equations are thus obtained for a chosen set of single-particle and two-particle (and possibly higher-order) moments. Analytical results are derived for generalized Gaussian closures including the dynamic pair distribution function and a two-particle correction to the current density. The maximum-entropy closure conditions are found to involve the Kirkwood superposition approximation.

  5. Current Research.

    Science.gov (United States)

    Hunt, Mary Alice

    1981-01-01

    Describes a doctoral dissertation entitled "World-Future Images in Childrens Literature" which analyzed books on science fiction or utopian fiction by 43 authors of children's literature to determine whether presentations were optimistic or pessimistic. Results indicating generally optimistic stories are discussed, as well as strengths and…

  6. Observable currents in lattice field theories

    CERN Document Server

    Zapata, José A

    2016-01-01

    Observable currents are spacetime local objects that induce physical observables when integrated on an auxiliary codimension one surface. Since the resulting observables are independent of local deformations of the integration surface, the currents themselves carry most of the information about the induced physical observables. I study observable currents in a multisymplectic framework for Lagrangian field theory over discrete spacetime. A weak version of observable currents preserves many of their properties, while inducing a family of observables capable of separating points in the space of physically distinct solutions. A Poisson bracket gives the space of observable currents the structure of a Lie algebra. Peierls bracket for bulk observables gives an algebra homomorphism mapping equivalence classes of bulk observables to weak observable currents. The study covers scalar fields, nonlinear sigma models and gauge theories (including gauge theory formulations of general relativity) on the lattice. Even when ...

  7. Sediment Movement in Periodic Alternating Current

    Institute of Scientific and Technical Information of China (English)

    CAO Zude; KONG Lingshuang; LIU Defu

    2002-01-01

    The present paper summarizes the results of previous studies, including the structure and principle of the rotaryring flume for researching the fine sediment movement, the mechanism of the flume, method of eliminating the influence ofthe centrifugal force and sediment movement experiments with periodic alternating current. Also included are the experi-ment-based relationship among sediment concentration, bed shear stress and silt carrying capacity, a proposed erosion-depo-sition function and bed erosion-deposition calculation together with the results of verification.

  8. Current focusing and steering: modeling, physiology, and psychophysics.

    Science.gov (United States)

    Bonham, Ben H; Litvak, Leonid M

    2008-08-01

    Current steering and current focusing are stimulation techniques designed to increase the number of distinct perceptual channels available to cochlear implant (CI) users by adjusting currents applied simultaneously to multiple CI electrodes. Previous studies exploring current steering and current focusing stimulation strategies are reviewed, including results of research using computational models, animal neurophysiology, and human psychophysics. Preliminary results of additional neurophysiological and human psychophysical studies are presented that demonstrate the success of current steering strategies in stimulating auditory nerve regions lying between physical CI electrodes, as well as current focusing strategies that excite regions narrower than those stimulated using monopolar configurations. These results are interpreted in the context of perception and speech reception by CI users. Disparities between results of physiological and psychophysical studies are discussed. The differences in stimulation used for physiological and psychophysical studies are hypothesized to contribute to these disparities. Finally, application of current steering and focusing strategies to other types of auditory prostheses is also discussed.

  9. RESULTS OF SLICE MEASUREMENTS

    CERN Document Server

    Rudolph, J

    2011-01-01

    The linear accelerator ELBE delivers high-brightness electron bunches to multiple user stations, including two IR-FEL oscillators [1], [2]. In the framework of an upgrade program the current thermionic injector is being replaced by a SRF-photoinjector [3], [4]. The SRF injector promises higher beam quality, especially required for future experiments with high power laser radiation. During the commissioning phase, the SRF-injector was running in parallel to the thermionic gun. After installation of a injection beamline (dogleg), beam from the SRF-injector can now be injected into the ELBE linac. Detailed characterization of the electron beam quality delivered by the new electron injector includes vertical slice emittance measurements in addition to measurements of projected emittance values. This report gives an overview of the status of the project and summarizes first measurement results as well as results of simulations performed with measurement settings.

  10. The evolution of doses in the IEA-R1 reactor environment and tendencies based on the current results; Evolucao das doses no ambiente do Reator IEA-R1 e tendencias com base nos resultados atuais

    Energy Technology Data Exchange (ETDEWEB)

    Toyoda, Eduardo Yoshio

    2016-11-01

    The IPEN / CNEN-SP have a Nuclear Research Reactor-NRR named IEA-R1, in operation from 1957. It is an open swimming pool reactor using light water as shielding, moderator and as cooling, the volume of this pool is 273m{sup 3}.Until 1995 the reactor operated daily at a power of 2,0 MW. From June of that year, after a few safety modifications the reactor began operating in continuous way from Monday to Wednesday without shutdown totalizing 64 hours per week and the power was increased to 4,5MW also. Because of these changes, continuous operation and increased power, workers' doses would tend to increase. In the past several studies were conducted seeking ways to reduce the workers' doses. A study was made on the possibility to introduce a shielding at the top of the reactor core with a hot water layer. Studies have shown that a major limitation for operating a reactor at high power comes from the gamma radiation emitted by the sodium-24. Other elements such as magnesium-27, aluminum-28, Argon-51, contribute considerably to the water activity of the pool. The introduction of a hot water layer on the swimming pool would form a layer of surface, stable and free of radioactive elements with a 1.5m to 2m thickness creates a shielding to radiation from radioactive elements dissolved in water. Optimization studies proved that the installation of the hot layer was not necessary for the regime and the current power reactor operation, because other procedures adopted were more effective. From this decision the Radiological Protection Reactor Team, set up a dose assessment program to ensure them remained in low values based on principles established in national and international standards. The purpose of this paper is to analyze the individual doses of OEI (Occupationally Exposed Individual), which will be checked increasing doses resulting from recent changes in reactor operation regime and suggested viable safety and protection options, in the first instance to

  11. 超高频雷达海洋表面流的探测结果与分析%Results and analysis of surface current based on UHF radar

    Institute of Scientific and Technical Information of China (English)

    文必洋; 李艳; 侯义东; 杨静

    2016-01-01

    近岸海域地形、海流复杂,而超高频雷达系统具有较高距离分辨率、小发射功率的特点,波长介于高频电磁波和微波之间,能同时提取海浪毛细波与重力波信息,与波浪作用比较敏感,能实现近海海洋动力参数的精细测量.不同于高频雷达回波谱,超高频雷达回波中一阶峰、二阶峰展宽严重并混叠在一起,难以划分一阶峰区域,因此,文中系统设计采用数字波束形成进行流速方位提取.雷达反演的流速结果与浮标数据的相关系数为0.88,但是均方根误差很大.通过分析,得出海洋表面流速不仅受到潮汐效应、地球自转的影响,当地风速在很大程度上也会影响表面流速的结论.%Ultra high frequency(UHF)radar has the characteristics of high range resolution and low-power,which can extract information of both capillary wave and gravity wave with the wavelength be-tween high frequency and microwave.It is possible to obtain precise monitoring of the coastal ocean dy-namics parameters by UHF radar,though the offshore topography and ocean surface current are complex. UHF radar is different from HF radar,since the first-order peak and second-order spectrum are indistin-guishable in the sea echo spectrum.It is difficult to extract first-order peak,therefore,multiple signal classification algorithm (MUSIC)is unavailable and digital beam-forming(DBF)is used in extracting the radial velocity.After a month,the radar and buoy datais highly correlated with a coefficient of 0.88,how-ever,the root mean square error is large.The results show that the velocity of the ocean surface is influ-enced not only by the tidal effect and the rotationof the earth,but also by the local wind speed.

  12. Opioid dependence treatment, including buprenorphine/naloxone.

    Science.gov (United States)

    Raisch, Dennis W; Fye, Carol L; Boardman, Kathy D; Sather, Mike R

    2002-02-01

    To review opioid dependence (OD) and its treatment. Pharmacologic treatments, including the use of buprenorphine/naloxone, are presented. Pharmaceutical care functions for outpatient OD treatment are discussed. Primary and review articles were identified by MEDLINE and HEALTHSTAR searches (from 1966 to November 2000) and through secondary sources. Tertiary sources were also reviewed regarding general concepts of OD and its treatment. Relevant articles were reviewed after identification from published abstracts. Articles were selected based on the objectives for this article. Studies of the treatment of OD with buprenorphine were selected based on the topic (pharmacology, pharmacokinetics, adverse reactions) and study design (randomized, controlled clinical trials in patients with OD with active/placebo comparisons and/or comparisons of active OD treatments). Articles regarding pharmacists' activities in the treatment and prevention of OD were reviewed for the pharmaceutical care section. OD is considered a medical disorder with costly adverse health outcomes. Although methadone maintenance treatment (MMT) is cost-effective for OD, only about 12% of individuals with OD receive this treatment. Psychological and pharmacologic modalities are used to treat OD, but patients often relapse. Drug therapy includes alpha 2-agonists for withdrawal symptoms, detoxification regimens with or without opioids, opioid antagonists, and opioid replacement including methadone, levomethadyl acetate, and buprenorphine. The Drug Addiction Treatment Act of 1999 allows for office-based opioid replacement therapies. Sublingual buprenorphine with naloxone can be used in this milieu. Buprenorphine with naloxone is currently under new drug application review with the Food and Drug Administration. Clinical research shows buprenorphine to be equal in effectiveness to methadone, but safer in overdose due to its ceiling effect on respiratory depression. It has lower abuse potential and fewer

  13. Current Trends in and Indications for Endoscopy-Assisted Breast Surgery for Breast Cancer: Results from a Six-Year Study Conducted by the Taiwan Endoscopic Breast Surgery Cooperative Group.

    Directory of Open Access Journals (Sweden)

    Hung-Wen Lai

    Full Text Available Endoscopy-assisted breast surgery (EABS performed through minimal axillary and/or periareolar incisions is a possible alternative to open surgery for certain patients with breast cancer. In this study, we report the early results of an EABS program in Taiwan.The medical records of patients who underwent EABS for breast cancer during the period May 2009 to December 2014 were collected from the Taiwan Endoscopic Breast Surgery Cooperative Group database. Data on clinicopathologic characteristics, type of surgery, method of breast reconstruction, complications and recurrence were analyzed to determine the effectiveness and oncologic safety of EABS in Taiwan.A total of 315 EABS procedures were performed in 292 patients with breast cancer, including 23 (7.8% patients with bilateral disease. The number of breast cancer patients who underwent EABS increased initially from 2009 to 2012 and then stabilized during the period 2012-2014. The most commonly performed EABS was endoscopy-assisted total mastectomy (EATM (85.4% followed by endoscopy-assisted partial mastectomy (EAPM (14.6%. Approximately 74% of the EATM procedures involved breast reconstruction, with the most common types of reconstruction being implant insertion and autologous pedicled TRAM flap surgery. During the six-year study period, there was an increasing trend in the performance of EABS for the management of breast cancer when total mastectomy was indicated. The positive surgical margin rate was 1.9%. Overall, the rate of complications associated with EABS was 15.2% and all were minor and wound-related. During a median follow-up of 26.8 (3.3-68.6 months, there were 3 (1% cases of local recurrence, 1 (0.3% case of distant metastasis and 1 (0.3% death.The preliminary results from the EABS program in Taiwan show that EABS is a safe procedure and results in acceptable cosmetic outcome. These findings could help to promote this under-used surgical technique in the field of breast cancer.

  14. BOOK REVIEW: The Current Comparator

    Science.gov (United States)

    Petersons, Oskars

    1989-01-01

    . One would hardly find a standards laboratory today without an instrument employing a current comparator. The NRC program, now nearing the end of its third decade, has resulted in a large number of papers in technical journals. The fact that the results of the current-comparator program are now documented in a well-written book is a most welcome development. The material in the book is well organized and divided into seven chapters. Chapter 1 deals very briefly with the historical aspects of the development, including related work in other organizations. Chapter 2 is the longest, occupying one third of the book. It presents the background theory; the definitions and origins of the errors; and the related concepts and devices including two-stage current transformers, electronic methods for improving the performance of current transformers, and null detectors. The idea of the current comparator is developed starting from Ampere's law; and then progressing to the practical realization of measuring the line integral of the magnetic field surrounding an electric current. Such an approach, as opposed to the more common methods of analyzing transformers, has a tutorial value in explaining how the current balance is achieved. Such analysis is intuitive for air-core sensing coils with infinitesimal cross-sections and uniform winding densities. The intuitive understanding, however, becomes less obvious when high-permeability magnetic cores are used. The subject of errors is discussed thoroughly. For errors of magnetic origin, ample experimental data are provided to support the hypothesis for the cause of such errors. The cause is discussed in a macroscopic sense (non-uniform effective permeability along the torus) without going into design and processing details which could be responsible for the non-uniformities. For capacitive errors, equations have been developed to compute them from geometrical considerations. Techniques are presented to reduce both types of errors shielding

  15. Ocular tuberculosis: current perspectives

    Directory of Open Access Journals (Sweden)

    Shakarchi FI

    2015-11-01

    Full Text Available Faiz I Shakarchi1,21Ibn Al-Haetham Teaching Eye Hospital, 2Department of Opthalmology, Medical College, Al-Mustansiriya University, Baghdad, IraqAbstract: The World Health Organization currently estimates that nearly two billion people, or one-third of the world’s population, are infected by tuberculosis, and that roughly 10% of the infected people are symptomatic. Tuberculosis affects the lungs in 80% of patients, while in the remaining 20% the disease may affect other organs, including the eye. Uveitis can be seen concurrently with tuberculosis, but a direct association is difficult to prove. Ocular tuberculosis is usually not associated with clinical evidence of pulmonary tuberculosis, as up to 60% of extrapulmonary tuberculosis patients may not have pulmonary disease. The diagnosis of tuberculous uveitis is often problematic and in nearly all reported cases, the diagnosis was only presumptive. Tuberculous uveitis is a great mimicker of various uveitis entities and it can be considered in the differential diagnosis of any type of intraocular inflammation. It is still unknown if ocular manifestations result from a direct mycobacterium infection or hypersensitivity reaction and this is reflected on the management of tuberculous uveitis. Prevalence of tuberculosis as an etiology of uveitis may reach up to 10% in endemic areas. Tuberculous uveitis is a vision-threatening disease that inevitably leads to blindness if not properly diagnosed and treated. The aim of this review is to illustrate the various clinical features and management of presumed tuberculous uveitis. The current review focuses on the diagnostic criteria, significance of tuberculin skin test, and use of systemic corticosteroids in the management of tuberculous uveitis as recommended in recent publications.Keywords: tuberculosis, uveitis, choroiditis, tuberculin skin test

  16. The Bransfield Gravity Current

    Science.gov (United States)

    Sangrà, Pablo; Stegner, Alexander; Hernández-Arencibia, Mónica; Marrero-Díaz, Ángeles; Salinas, Carolina; Aguiar-González, Borja; Henríquez-Pastene, Cristian; Mouriño-Carballido, Beatriz

    2017-01-01

    Using in situ data and laboratory experiments, we show that the circulation of the Bransfield Current (BC) around the South Shetland Islands (SSI) may be characterized in terms of a propagating buoyant gravity current. First, we describe the SSI hydrography and some drifter trajectories, paying special attention to the recirculation of the BC at the northeastern tip and northern slopes of the SSI. We observed that when the northeastward-flowing BC reaches the northeastern tip of the SSI, it recirculates around an anticyclonic mesoscale eddy that has not previously been reported in this region. Part of this recirculating water then proceeds southwest along the northern SSI shelf break as a narrow baroclinic jet and another part join the Antarctic Circumpolar Current. Consequently, the cross-slope gradients of properties strengthen, and the southern boundary of the Antarctic Circumpolar Current becomes a nearly submesoscale ( 10 km) front. Second, we compare the observations with buoyant gravity current laboratory experiments in an open basin setup where the SSI topographic barrier is represented by a central wall. The resulting circulation of the buoyant gravity current around the wall mirrors our in situ observations. First, a narrow buoyant gravity current flows northeastward along the southern boundary of the wall. Once the head of the buoyant gravity current reaches the tip of the wall, a recirculating anticyclonic vortex is generated, and the buoyant gravity current then proceeds westward along the north side of the wall. This circulation of the BC around the SSI as a buoyant gravity current may contribute to the fertilization of the waters around the SSI, as suggested by previously reported distributions of nutrients and phytoplankton.

  17. Current power plant

    Energy Technology Data Exchange (ETDEWEB)

    Nickell, J.H.

    1979-03-06

    A current power plant is described that includes a shaft mounted turbine wheel for employment in water current, a housing adjacent the impeller and to which the shaft extends, a ramp positioned on the upstream side of the impellar, and a frame on which the turbine wheel is mounted. The frame is mounted by rollers on a tract such that the impeller and frame may be rolled on the tracks inside the housing, whereafter doors are closed, and water around the turbine wheel may be pumped out to facilitate turbine repair.

  18. Currents in supersymmetric field theories

    CERN Document Server

    Derendinger, Jean-Pierre

    2016-01-01

    A general formalism to construct and improve supercurrents and source or anomaly superfields in two-derivative N=1 supersymmetric theories is presented. It includes arbitrary gauge and chiral superfields and a linear superfield coupled to gauge fields. These families of supercurrent structures are characterized by their energy-momentum tensors and R currents and they display a specific relation to the dilatation current of the theory. The linear superfield is introduced in order to describe the gauge coupling as a background (or propagating) field. Supersymmetry does not constrain the dependence on this gauge coupling field of gauge kinetic terms and holomorphicity restrictions are absent. Applying these results to an effective (Wilson) description of super-Yang-Mills theory, matching or cancellation of anomalies leads to an algebraic derivation of the all-order NSVZ beta function.

  19. Umbilical metastases: current viewpoint

    Directory of Open Access Journals (Sweden)

    Egidi Federico

    2005-02-01

    Full Text Available Abstract Background Umbilical metastases from a malignant neoplasm, also termed Sister Mary Joseph's nodule, are not commonly reported in the English literature, and they have usually been considered as a sign of a poor prognosis for the patient. The present article reports on the current view point on umbilical metastasis besides discussing the epidemiology, clinical presentation, pathophysiology and treatment. Method A search of Pubmed was carried out using the term 'umblic*' and 'metastases' or metastasis' revealed no references. Another search was made using the term "Sister Joseph's nodule" or sister Joseph nodule" that revealed 99 references. Of these there were 14 review articles, however when the search was limited to English language it yielded only 20 articles. Articles selected from these form the basis of this report along with cross references. Results The primary lesions usually arise from gastrointestinal or genitourinary tract malignancies and may be the presenting symptom or sign of a primary tumour in an unknown site. Conclusion A careful evaluation of all umbilical lesions, including an early biopsy if appropriate, is recommended. Recent studies suggest an aggressive surgical approach combined with chemotherapy for such patients may improve survival.

  20. Educational Technology: Effective Leadership and Current Initiatives

    Science.gov (United States)

    Courville, Keith

    2011-01-01

    (Purpose) This article describes the basis for effective educational technology leadership and a few of the current initiatives and impacts that are a result of the aforementioned effective leadership. (Findings) Topics addressed in this paper include: (1) the role of the educational technology leader in an educational setting; (2) an examination…

  1. Current practice for pulmonary hypertension

    Institute of Scientific and Technical Information of China (English)

    Toru Satoh

    2014-01-01

    Objective To investigate the current practice of pulmonary hypertension including current epidemiology,diagnosis and treatment.Data sources The review was based on data obtained from the published articles and guidelines.Study selection Articles with high level of evidence or current best evidence in each issue were selected to be reviewed.Results Overall prevalence of pulmonary hypertension was 0.3% to 6% with left heart disease occupying the most proportion,followed by pulmonary disease,pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension.In diagnosis,a flow diagram of diagnosis of pulmonary hypertension,differential diagnosis of pulmonary hypertension and how to determine the severity of pulmonary hypertension are explained including recent development of magnetic resonance imaging and gene abnormality study on bone morphogenetic protein receptor Ⅱ.In treatment,newlydeveloped pulmonary vasodilators and the way to use them are shown to treat pulmonary hypertension.Conclusion Safer and more effective treatment algorithm and basic researches and clinical trials are warranted to be explored.

  2. The COG database: an updated version includes eukaryotes

    Directory of Open Access Journals (Sweden)

    Sverdlov Alexander V

    2003-09-01

    Full Text Available Abstract Background The availability of multiple, essentially complete genome sequences of prokaryotes and eukaryotes spurred both the demand and the opportunity for the construction of an evolutionary classification of genes from these genomes. Such a classification system based on orthologous relationships between genes appears to be a natural framework for comparative genomics and should facilitate both functional annotation of genomes and large-scale evolutionary studies. Results We describe here a major update of the previously developed system for delineation of Clusters of Orthologous Groups of proteins (COGs from the sequenced genomes of prokaryotes and unicellular eukaryotes and the construction of clusters of predicted orthologs for 7 eukaryotic genomes, which we named KOGs after eukaryotic orthologous groups. The COG collection currently consists of 138,458 proteins, which form 4873 COGs and comprise 75% of the 185,505 (predicted proteins encoded in 66 genomes of unicellular organisms. The eukaryotic orthologous groups (KOGs include proteins from 7 eukaryotic genomes: three animals (the nematode Caenorhabditis elegans, the fruit fly Drosophila melanogaster and Homo sapiens, one plant, Arabidopsis thaliana, two fungi (Saccharomyces cerevisiae and Schizosaccharomyces pombe, and the intracellular microsporidian parasite Encephalitozoon cuniculi. The current KOG set consists of 4852 clusters of orthologs, which include 59,838 proteins, or ~54% of the analyzed eukaryotic 110,655 gene products. Compared to the coverage of the prokaryotic genomes with COGs, a considerably smaller fraction of eukaryotic genes could be included into the KOGs; addition of new eukaryotic genomes is expected to result in substantial increase in the coverage of eukaryotic genomes with KOGs. Examination of the phyletic patterns of KOGs reveals a conserved core represented in all analyzed species and consisting of ~20% of the KOG set. This conserved portion of the

  3. PROPERTIES AND MICROSTRUCTURE OF CEMENT PASTE INCLUDING RECYCLED CONCRETE POWDER

    Directory of Open Access Journals (Sweden)

    Jaroslav Topič

    2017-02-01

    Full Text Available The disposal and further recycling of concrete is being investigated worldwide, because the issue of complete recycling has not yet been fully resolved. A fundamental difficulty faced by researchers is the reuse of the recycled concrete fines which are very small (< 1 mm. Currently, full recycling of such waste fine fractions is highly energy intensive and resulting in production of CO2. Because of this, the only recycling methods that can be considered as sustainable and environmentally friendly are those which involve recycled concrete powder (RCP in its raw form. This article investigates the performance of RCP with the grain size < 0.25 mm as a potential binder replacement, and also as a microfiller in cement-based composites. Here, the RCP properties are assessed, including how mechanical properties and the microstructure are influenced by increasing the amount of the RCP in a cement paste (≤ 25 wt%.

  4. Current concepts in osteolysis.

    Science.gov (United States)

    Ollivere, B; Wimhurst, J A; Clark, I M; Donell, S T

    2012-01-01

    The most frequent cause of failure after total hip replacement in all reported arthroplasty registries is peri-prosthetic osteolysis. Osteolysis is an active biological process initiated in response to wear debris. The eventual response to this process is the activation of macrophages and loss of bone. Activation of macrophages initiates a complex biological cascade resulting in the final common pathway of an increase in osteolytic activity. The biological initiators, mechanisms for and regulation of this process are beginning to be understood. This article explores current concepts in the causes of, and underlying biological mechanism resulting in peri-prosthetic osteolysis, reviewing the current basic science and clinical literature surrounding the topic.

  5. Simulation of Gravity Currents Using VOF Model

    Institute of Scientific and Technical Information of China (English)

    邹建锋; 黄钰期; 应新亚; 任安禄

    2002-01-01

    By the Volume of Fluid (VOF) multiphase flow model two-dimensional gravity currents with three phases including air are numerically simulated in this article. The necessity of consideration of turbulence effect for high Reynolds numbers is demonstrated quantitatively by LES (the Large Eddy Simulation) turbulence model. The gravity currents are simulated for h ≠ H as well as h = H, where h is the depth of the gravity current before the release and H is the depth of the intruded fluid. Uprising of swell occurs when a current flows horizontally into another lighter one for h ≠ H. The problems under what condition the uprising of swell occurs and how long it takes are considered in this article. All the simulated results are in reasonable agreement with the experimental results available.

  6. Current Conveyor Based Window Comparator Circuits

    Directory of Open Access Journals (Sweden)

    Sudhanshu Maheshwari

    2016-01-01

    Full Text Available This paper introduces a new window comparator circuit utilizing a new current conveyor and two diodes, operable at ±1.25 V and capable of accurately detecting the voltage windows. Another modified circuit with distinct binary levels suited for automatic control applications is also suggested. Exhaustive simulation results showing detection of windows, as small as 50 mV and as high as 1 V, are included. Comparisons are further drawn with the traditional operational amplifier based circuit and the new circuit is found to benefit from the use of current-mode active element, namely, Extra-X Current Controlled Current Conveyor. The proposed theory is well supported through simulation results.

  7. Current state of the art, multimodality research and future visions for the treatment of patients with prostate cancer: consensus results from "Challenges and Chances in Prostate Cancer Research Meeting 2013".

    Science.gov (United States)

    Combs, Stephanie E; Debus, Jürgen; Feick, Günter; Hadaschik, Boris; Hohenfellner, Markus; Schüle, Roland; Zacharias, Jens-Peter; Schwardt, Malte

    2014-11-04

    A brainstorming and consensus meeting organized by the German Cancer Aid focused on modern treatment of prostate cancer and promising innovative techniques and research areas. Besides optimization of screening algorithms, molecular-based stratification and individually tailored treatment regimens will be the future of multimodal prostate cancer management. Effective interdisciplinary structures, including biobanking and data collection mechanisms are the basis for such developments.

  8. Imaging of axial spondyloarthritis including ankylosing spondylitis.

    Science.gov (United States)

    Braun, J; Baraliakos, X

    2011-03-01

    New bone formation of the vertebral column is pathognomonic for ankylosing spondylitis (AS), while acute and/or chronic changes in the sacroiliac joints are relevant for diagnosis. The 'gold standard' for assessment of structural changes in AS are conventional radiographs, while MRI is useful to assess inflammation. Recent MRI studies have shown that the lower half of the thoracic spine is most commonly affected in AS. Scoring tools for spinal inflammation such as the ASspiMRI-a have been proposed, successfully used in large clinical trials and compared in a multireader experiment; none was finally preferred by OMERACT. Quantification of structural spinal AS changes is performed by the modified Stokes AS Spine Score (mSASSS), which evaluates lateral cervical and lumbar radiographs. Two years was identified as the shortest possible follow-up time based on the reliability and sensitivity to change of the mSASSS. A potential disadvantage of the mSASSS is that the thoracic spine is not included. Recent data based on the mSASSS have suggested that tumour necrosis factor blockers do not inhibit radiographic progression in AS. Since the mean radiographic change is reported to be less than 1 syndesmophyte over 2 years, the sensitivity to change of the mSASSS has been questioned. However, in one study where continuous non-steroidal anti-inflammatory drugs use was compared with on-demand use, a difference between these two methods of drug intake was reported. The face and construct validity of the mSASSS has been criticised because a score of ´1´ contains a mixture of osteodestructive (erosions) and osteoproliferative changes (squaring and sclerosis). A new scoring system, the RASSS, which concentrates only on bone formation and which includes the lower part of the thoracic spine is currently being evaluated. The relationship between inflammation and new bone formation in AS has recently been investigated. Low sclerostin and DKK-1 serum levels, both inhibitors of bone

  9. Generalized fluid theory including non-Maxwellian kinetic effects

    Science.gov (United States)

    Izacard, Olivier

    2017-04-01

    The results obtained by the plasma physics community for the validation and the prediction of turbulence and transport in magnetized plasmas come mainly from the use of very central processing unit (CPU)-consuming particle-in-cell or (gyro)kinetic codes which naturally include non-Maxwellian kinetic effects. To date, fluid codes are not considered to be relevant for the description of these kinetic effects. Here, after revisiting the limitations of the current fluid theory developed in the 19th century, we generalize the fluid theory including kinetic effects such as non-Maxwellian super-thermal tails with as few fluid equations as possible. The collisionless and collisional fluid closures from the nonlinear Landau Fokker-Planck collision operator are shown for an arbitrary collisionality. Indeed, the first fluid models associated with two examples of collisionless fluid closures are obtained by assuming an analytic non-Maxwellian distribution function (e.g. the INMDF (Izacard, O. 2016b Kinetic corrections from analytic non-Maxwellian distribution functions in magnetized plasmas. Phys. Plasmas 23, 082504) that stands for interpreted non-Maxwellian distribution function). One of the main differences with the literature is our analytic representation of the distribution function in the velocity phase space with as few hidden variables as possible thanks to the use of non-orthogonal basis sets. These new non-Maxwellian fluid equations could initiate the next generation of fluid codes including kinetic effects and can be expanded to other scientific disciplines such as astrophysics, condensed matter or hydrodynamics. As a validation test, we perform a numerical simulation based on a minimal reduced INMDF fluid model. The result of this test is the discovery of the origin of particle and heat diffusion. The diffusion is due to the competition between a growing INMDF on short time scales due to spatial gradients and the thermalization on longer time scales. The results

  10. Recent Results from the ZEUS Experiment

    CERN Document Server

    Smith, W H; Abramowicz, H; Adamczyk, L; Adamus, M; Adler, V; Aghuzumtsyan, G; Antonioli, P; Antonov, A; Arneodo, M; Bailey, D S; Bamberger, A; Barakbaev, A N; Barbagli, G; Barbi, M; Bari, G; Barreiro, F; Bartsch, D; Basile, M; Bauerdick, L A T; Behrens, U; Bell, M; Bellagamba, L; Benen, A; Bertolin, A; Bhadra, S; Bloch, I; Bodmann, B; Bold, T; Boos, E G; Borras, K; Boscherini, D; Brock, I; Brook, N H; Brugnera, R; Brümmer, N; Bruni, A; Bruni, G; Bussey, P J; Butterworth, J M; Bylsma, B; Caldwell, A; Capua, M; Cara Romeo, G; Carli, T; Carlin, R; Catterall, C D; Chekanov, S; Chiochia, V; Chwastowski, J; Ciborowski, J; Ciesielski, R; Cifarelli, Luisa; Cindolo, F; Cloth, P; Cole, J E; Collins-Tooth, C; Contin, A; Cooper-Sarkar, A M; Coppola, N; Cormack, C; Corradi, M; Corriveau, F; Cottrell, A; D'Agostini, Giulio; Dal Corso, F; Danilov, P; Dannheim, D; De Pasquale, S; Dementiev, R K; Derrick, M; Deshpande, Abhay A; Devenish, R C E; Dhawan, S; Dolgoshein, B A; Doyle, A T; Drews, G; Durkin, L S; Dusini, S; Eisenberg, Y; Ermolov, P F; Eskreys, Andrzej; Ferrando, J; Ferrero, M I; Figiel, J; Filges, D; Foster, B; Foudas, C; Fourletov, S; Fourletova, J; Fricke, U; Fusayasu, T; Gabareen, A; Gallo, E; Garfagnini, A; Geiser, A; Genta, C; Gialas, I; Giusti, P; Gladilin, L K; Gladkov, D; Glasman, C; Gliga, S; Goers, S; Golubkov, Yu A; Goncalo, R; González, O; Göttlicher, P; Grabowska-Bold, I; Grijpink, S; Grzelak, G; Gutsche, O; Gwenlan, C; Haas, T; Hain, W; Hall-Wilton, R; Hamatsu, R; Hamilton, J; Hanlon, S; Hart, J C; Hartmann, H; Hartner, G; Hartner, G F; Heaphy, E A; Heath, G P; Heath, H F; Helbich, M; Heusch, C A; Hilger, E; Hillert, S; Hirose, T; Hochman, D; Holm, U; Iacobucci, G; Iga, Y; Inuzuka, M; Irrgang, P; Jakob, H P; Jones, T W; Kagawa, S; Kahle, B; Kaji, H; Kananov, S; Kappes, A; Kataoka, Y; Yamazaki, M; Katkov, I I; Katz, U F; Kcira, D; Khein, L A; Kim, J Y; Kim, Y K; Kind, O; Kisielewska, D; Kitamura, S; Klimek, K; Koffeman, E; Kohno, T; Kooijman, P; Koop, T; Korzhav, I A; Kotanski, A; Kötz, U; Kowal, A M; Kowal, M; Kowalski, H; Kowalski, T; Krakauer, D; Kramberger, G; Kreisel, A; Krumnack, N; Kuze, M; Kuzmin, V A; Labarga, L; Labes, H; Lainesse, J; Lammers, S; Lee, J H; Lee, S W; Lelas, D; Levchenko, B B; Levman, G M; Levy, A; Li, L; Lightwood, M S; Lim, H; Lim, I T; Limentani, S; Ling, T Y; Liu, X; Löhr, B; Lohrmann, E; Loizides, J H; Long, K R; Longhin, A; Lukina, O Yu; Lupi, A; Luzniak, P; Maddox, E; Magill, S; Mankel, R; Margotti, A; Marini, G; Martin, J F; Mastroberardino, A; Matsuzawa, K; Mattingly, M C K; McCubbin, N A; Mellado, B; Melzer-Pellmann, I A; Menary, S R; Metlica, F; Meyer, U; Milite, M; Mirea, A; Monaco, V; Montanari, A; Moritz, M; Musgrave, B; Nagano, K; Nania, R; Nguyen, C N; Nigro, A; Ning, Y; Nishimura, T; Notz, D; Nowak, R J; Oh, B Y; Olkiewicz, K; Pac, M Y; Padhi, S; Paganis, S; Palmonari, F; Parenti, A; Park, I H; Patel, S; Paul, E; Pavel, N; Pawlak, J M; Pelfer, P G; Pellegrino, A; Pesci, A; Petrucci, M C; Piotrzkowski, K; Plucinsky, P P; Pokrovskiy, N S; Polini, A; Posocco, M; Proskuryakov, A S; Przybycien, M B; Rautenberg, J; Raval, A; Reeder, D D; Ren, Z; Renner, R; Repond, J; Riveline, U; Karshon, M; Robins, S; Rodrigues, E; Rosin, M; Rurua, L; Ruspa, M; Sacchi, R; Salehi, H; Sartorelli, G; Savin, A A; Saxon, D H; Schagen, S; Schioppa, M; Schlenstedt, S; Schmidke, W B; Schneekloth, U; Sciulli, F; Scott, J; Selonke, F; Shcheglova, L M; Skillicorn, I O; Slominski, W; Soares, M; Solano, A; Son, D; Sosnovtsev, V V; Stairs, D G; Stanco, L; Standage, J; Stifutkin, A; Stoesslein, U; Stonjek, S; Stopa, P; Straub, P B; Suchkov, S; Susinno, G; Suszycki, L; Sutton, M R; Sztuk, J; Szuba, D; Szuba, J; Tandler, J; Tapper, A D; Tapper, R J; Tassi, E; Tawara, T; Terron, J; Tiecke, H G; Tokushuku, K; Tsurugai, T; Turcato, M; Tymieniecka, T; Ukleja, A; Ukleja, J; Vázquez, M; Velthuis, J J; Vlasov, N N; Voss, K C; Walczak, R; Walsh, R; Wang, M; Weber, A; Wessoleck, H; West, B J; Whitmore, J J; Wick, K; Wiggers, L; Wills, H H; Wing, M; Wolf, G; Yamada, S; Yamashita, T; Yoshida, R; Youngman, C; Zawiejski, L; Zeuner, W; Zhautykov, B O; Zichichi, A; Ziegler, A; Zotkin, S A; De Wolf, E; Del Peso, J

    2004-01-01

    A summary of recent results from ZEUS is presented. New ZEUS results from HERA-1 data include Structure Functions, QCD fits, analysis of hadronic final states, precision measurements of alpha_s, production of heavy flavor mesons and baryons and studies of diffraction. Results from the new HERA-II running include the measurement of the cross section for polarized charged current events and charm events tagged with the new ZEUS vertex detector.

  11. Critical point anomalies include expansion shock waves

    Energy Technology Data Exchange (ETDEWEB)

    Nannan, N. R., E-mail: ryan.nannan@uvs.edu [Mechanical Engineering Discipline, Anton de Kom University of Suriname, Leysweg 86, PO Box 9212, Paramaribo, Suriname and Process and Energy Department, Delft University of Technology, Leeghwaterstraat 44, 2628 CA Delft (Netherlands); Guardone, A., E-mail: alberto.guardone@polimi.it [Department of Aerospace Science and Technology, Politecnico di Milano, Via La Masa 34, 20156 Milano (Italy); Colonna, P., E-mail: p.colonna@tudelft.nl [Propulsion and Power, Delft University of Technology, Kluyverweg 1, 2629 HS Delft (Netherlands)

    2014-02-15

    From first-principle fluid dynamics, complemented by a rigorous state equation accounting for critical anomalies, we discovered that expansion shock waves may occur in the vicinity of the liquid-vapor critical point in the two-phase region. Due to universality of near-critical thermodynamics, the result is valid for any common pure fluid in which molecular interactions are only short-range, namely, for so-called 3-dimensional Ising-like systems, and under the assumption of thermodynamic equilibrium. In addition to rarefaction shock waves, diverse non-classical effects are admissible, including composite compressive shock-fan-shock waves, due to the change of sign of the fundamental derivative of gasdynamics.

  12. Should Broca's area include Brodmann area 47?

    Science.gov (United States)

    Ardila, Alfredo; Bernal, Byron; Rosselli, Monica

    2017-02-01

    Understanding brain organization of speech production has been a principal goal of neuroscience. Historically, brain speech production has been associated with so-called Broca’s area (Brodmann area –BA- 44 and 45), however, modern neuroimaging developments suggest speech production is associated with networks rather than with areas. The purpose of this paper was to analyze the connectivity of BA47 ( pars orbitalis) in relation to language . A meta-analysis was conducted to assess the language network in which BA47 is involved. The Brainmap database was used. Twenty papers corresponding to 29 experimental conditions with a total of 373 subjects were included. Our results suggest that BA47 participates in a “frontal language production system” (or extended Broca’s system). The BA47  connectivity found is also concordant with a minor role in language semantics. BA47 plays a central role in the language production system.

  13. DEVELOPMENT OF WATER CIRCULATION MODEL INCLUDING IRRIGATION

    Science.gov (United States)

    Kotsuki, Shunji; Tanaka, Kenji; Kojiri, Toshiharu; Hamaguchi, Toshio

    It is well known that since agricultural water withdrawal has much affect on water circulation system, accurate analysis of river discharge or water balance are difficult with less regard for it. In this study, water circulation model composed of land surface model and distributed runoff model is proposed at 10km 10km resolution. In this model, irrigation water, which is estimated with land surface model, is introduced to river discharge analysis. The model is applied to the Chao Phraya River in Thailand, and reproduced seasonal water balance. Additionally, the discharge on dry season simulated with the model is improved as a result of including irrigation. Since the model, which is basically developed from global data sets, simulated seasonal change of river discharge, it can be suggested that our model has university to other river basins.

  14. Lead toxicity: Current concerns

    Energy Technology Data Exchange (ETDEWEB)

    Goyer, R.A. (Univ. of Western Ontario, London (Canada))

    1993-04-01

    Over the 20-year period since the first issue of Environmental Health Perspectives was published, there has been considerable progress in the understanding of the potential toxicity of exposure to lead. Many of these advances have been reviewed in published symposia, conferences, and review papers in EHP. This brief review identifies major advances as well as a number of current concerns that present opportunities for prevention and intervention strategies. The major scientific advance has been the demonstration that blood lead (PbB) levels of 10-15 micrograms/dL in newborn and very young infants result in cognitive and behavioral deficits. Further support for this observation is being obtained by prospective or longitudinal studies presently in progress. The mechanism(s) for the central nervous system effects of lead is unclear but involve lead interactions within calcium-mediated intracellular messenger systems and neurotransmission. Effects of low-level lead exposure on blood pressure, particularly in adult men, may be related to the effect of lead on calcium-mediated control of vascular smooth muscle contraction and on the renin-angiotensin system. Reproductive effects of lead have long been suspected, but low-level effects have not been well studied. Whether lead is a carcinogen or its association with renal adenocarcinoma is a consequence of cystic nephropathy is uncertain. Major risk factors for lead toxicity in children in the United States include nutrition, particularly deficiencies of essential metals, calcium, iron, and zinc, and housing and socioeconomic status. A goal for the year 2000 is to reduce prevalence of blood lead levels exceeding 15 micrograms/dL. 97 refs.

  15. Two-fluid turbulence including electron inertia

    Energy Technology Data Exchange (ETDEWEB)

    Andrés, Nahuel, E-mail: nandres@iafe.uba.ar; Gómez, Daniel [Instituto de Astronomía y Física del Espacio, CC. 67, suc. 28, 1428 Buenos Aires (Argentina); Departamento de Física, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Pabellón I, 1428 Buenos Aires (Argentina); Gonzalez, Carlos; Martin, Luis; Dmitruk, Pablo [Departamento de Fisica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires and IFIBA, CONICET, 1428 Buenos Aires (Argentina)

    2014-12-15

    We present a full two-fluid magnetohydrodynamic (MHD) description for a completely ionized hydrogen plasma, retaining the effects of the Hall current, electron pressure, and electron inertia. According to this description, each plasma species introduces a new spatial scale: the ion inertial length λ{sub i} and the electron inertial length λ{sub e}, which are not present in the traditional MHD description. In the present paper, we seek for possible changes in the energy power spectrum in fully developed turbulent regimes, using numerical simulations of the two-fluid equations in two-and-a-half dimensions. We have been able to reproduce different scaling laws in different spectral ranges, as it has been observed in the solar wind for the magnetic energy spectrum. At the smallest wavenumbers where plain MHD is valid, we obtain an inertial range following a Kolmogorov k{sup −5∕3} law. For intermediate wavenumbers such that λ{sub i}{sup −1}≪k≪λ{sub e}{sup −1}, the spectrum is modified to a k{sup −7∕3} power-law, as has also been obtained for Hall-MHD neglecting electron inertia terms. When electron inertia is retained, a new spectral region given by k>λ{sub e}{sup −1} arises. The power spectrum for magnetic energy in this region is given by a k{sup −11∕3} power law. Finally, when the terms of electron inertia are retained, we study the self-consistent electric field. Our results are discussed and compared with those obtained in the solar wind observations and previous simulations.

  16. Extending Newtonian Dynamics to Include Stochastic Processes

    Science.gov (United States)

    Zak, Michail

    2009-01-01

    A paper presents further results of continuing research reported in several previous NASA Tech Briefs articles, the two most recent being Stochastic Representations of Chaos Using Terminal Attractors (NPO-41519), [Vol. 30, No. 5 (May 2006), page 57] and Physical Principle for Generation of Randomness (NPO-43822) [Vol. 33, No. 5 (May 2009), page 56]. This research focuses upon a mathematical formalism for describing post-instability motions of a dynamical system characterized by exponential divergences of trajectories leading to chaos (including turbulence as a form of chaos). The formalism involves fictitious control forces that couple the equations of motion of the system with a Liouville equation that describes the evolution of the probability density of errors in initial conditions. These stabilizing forces create a powerful terminal attractor in probability space that corresponds to occurrence of a target trajectory with probability one. The effect in configuration space (ordinary three-dimensional space as commonly perceived) is to suppress exponential divergences of neighboring trajectories without affecting the target trajectory. As a result, the post-instability motion is represented by a set of functions describing the evolution of such statistical quantities as expectations and higher moments, and this representation is stable.

  17. Locomotive Assignment Optimization Including Train Delays

    Directory of Open Access Journals (Sweden)

    Sandra Kasalica

    2013-10-01

    Full Text Available Intention– Cyclic locomotive assignment planning is a specific type of organization of locomotive usage, and in fact, it means putting the complete workload to a closed chain, which is repeated periodically. The concept of cyclic locomotive assignment planning type organization in the area of train traction has proven in practice as the best one, but as it is made for in-advance defined timetable and without considering the stochastic nature of the timetable realization process, it leads to incompatibility in using locomotives. Methodology – Methodology defined in this paper contains: research of train delays on the Serbian Railways and Montenegrin Railways networks, analysis of the real system organization of locomotive usage in conditions of train delays, theoretical thesis of solving the problem of optimal cyclic locomotive assignment planning in conditions of train delays, designing of a model with algorithms, preparing the software package, testing the model and program with results, as well as the conclusions drawn from the complete research project. Results– The optimization model of cyclic locomotive assignment planning during the process of making timetable including train delays has been defined. Conclusion –The obtained results have shown as expected, that the larger delays of trains required a larger number of locomotives. However, by using this model it is possible to optimize the required number of locomotives, taking into account the real time delays of trains.

  18. Transformer current sensor for superconducting magnetic coils

    Science.gov (United States)

    Shen, Stewart S.; Wilson, C. Thomas

    1988-01-01

    A transformer current sensor having primary turns carrying a primary current for a superconducting coil and secondary turns only partially arranged within the primary turns. The secondary turns include an active winding disposed within the primary turns and a dummy winding which is not disposed in the primary turns and so does not experience a magnetic field due to a flow of current in the primary turns. The active and dummy windings are wound in opposite directions or connected in series-bucking relationship, and are exposed to the same ambient magnetic field. Voltages which might otherwise develop in the active and dummy windings due to ambient magnetic fields thus cancel out. The resultant voltage is purely indicative of the rate of change of current flowing in the primary turns.

  19. Strange neutral currents in nuclei

    CERN Document Server

    Ressell, M T; Aufderheide, M B; Bloom, S D; Resler, D A

    1995-01-01

    We examine the effects on the nuclear neutral current Gamow-Teller (GT) strength of a finite contribution from a polarized strange quark sea. We perform nuclear shell model calculations of the neutral current GT strength for a number of nuclei likely to be present during stellar core collapse. We compare the GT strength when a finite strange quark contribution is included to the strength without such a contribution. As an example, the process of neutral current nuclear de-excitation via \

  20. Improving the lattice axial vector current

    Energy Technology Data Exchange (ETDEWEB)

    Horsley, R. [Edinburgh Univ. (United Kingdom). School of Physics and Astronomy; Nakamura, Y. [RIKEN Advanced Institute for Computational Science, Kobe (Japan); Perlt, H.; Schiller, A. [Leipzig Univ. (Germany). Inst. fuer Theoretische Physik; Rakow, P.E.L. [Liverpool Univ. (United Kingdom). Theoretical Physics Div.; Schierholz, G. [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Zanotti, J.M. [Adelaide Univ. (Australia). CSSM, Dept. of Physics

    2015-11-15

    For Wilson and clover fermions traditional formulations of the axial vector current do not respect the continuum Ward identity which relates the divergence of that current to the pseudoscalar density. Here we propose to use a point-split or one-link axial vector current whose divergence exactly satisfies a lattice Ward identity, involving the pseudoscalar density and a number of irrelevant operators. We check in one-loop lattice perturbation theory with SLiNC fermion and gauge plaquette action that this is indeed the case including order O(a) effects. Including these operators the axial Ward identity remains renormalisation invariant. First preliminary results of a nonperturbative check of the Ward identity are also presented.

  1. Improving the lattice axial vector current

    CERN Document Server

    Horsley, R; Perlt, H; Rakow, P E L; Schierholz, G; Schiller, A; Zanotti, J M

    2015-01-01

    For Wilson and clover fermions traditional formulations of the axial vector current do not respect the continuum Ward identity which relates the divergence of that current to the pseudoscalar density. Here we propose to use a point-split or one-link axial vector current whose divergence exactly satisfies a lattice Ward identity, involving the pseudoscalar density and a number of irrelevant operators. We check in one-loop lattice perturbation theory with SLiNC fermion and gauge plaquette action that this is indeed the case including order $O(a)$ effects. Including these operators the axial Ward identity remains renormalisation invariant. First preliminary results of a nonperturbative check of the Ward identity are also presented.

  2. Generalized fluid theory including non-Maxwellian kinetic effects

    CERN Document Server

    Izacard, Olivier

    2016-01-01

    The results obtained by the plasma physics community for the validation and the prediction of turbulence and transport in magnetized plasma come mainly from the use of very CPU-consuming particle-in-cell or (gyro)kinetic codes which naturally include non-Maxwellian kinetic effects. To date, fluid codes are not considered to be relevant for the description of these kinetic effects. Here, after revisiting the limitations of the current fluid theory developed in the 19th century, we generalize the fluid theory including kinetic effects such as non-Maxwellian super-thermal tails with as few fluid equations as possible. The collisionless and collisional fluid closures from the nonlinear Landau Fokker-Planck collision operator are shown for an arbitrary collisionality. Indeed, the first fluid models associated with two examples of collisionless fluid closures are obtained by assuming an analytic non-Maxwellian distribution function (e.g., the INMDF [O. Izacard, Phys. Plasmas 23, 082504 (2016)]). One of the main dif...

  3. Haemophilus influenzae Disease (Including Hib) Symptoms

    Science.gov (United States)

    ... Search The CDC Cancel Submit Search The CDC Haemophilus influenzae Disease (Including Hib) Note: Javascript is disabled or ... and Symptoms Recommend on Facebook Tweet Share Compartir Haemophilus influenzae , including Hib, disease causes different symptoms depending on ...

  4. Current therapy of systemic sclerosis (scleroderma).

    Science.gov (United States)

    Müller-Ladner, U; Benning, K; Lang, B

    1993-04-01

    Treatment of systemic sclerosis (scleroderma) presents a challenge to both the patient and the physician. Established approaches include long-term physiotherapy, disease-modifying agents such as D-penicillamine, and treatment of organ involvement. These efforts are often unsatisfactory since the results are poor. However, recent advances include treatment of Raynaud's phenomenon (plasmapheresis, stanozolol, and prostacyclin analogues), scleroderma renal crisis (angiotensin-converting enzyme inhibitors), and gastric hypomotility (cisapride). This article covers the current approaches to the disease-modifying therapy including those related to the function of collagen-producing fibroblasts, vascular alterations, and the cellular and humoral immune system, as well as treatment of involved organs.

  5. Global Health - Cancer Currents Blog

    Science.gov (United States)

    A catalog of posts from NCI’s Cancer Currents blog on research related to cancer’s impact around the world. Includes posts on factors that influence global cancer incidence and mortality and new research initiatives.

  6. FDA Approvals - Cancer Currents Blog

    Science.gov (United States)

    A catalog of posts from NCI’s Cancer Currents blog on new Food and Drug Administration approvals of cancer drugs. All posts include summaries of the evidence to support the new approvals and what they mean for patients.

  7. Cancer Disparities - Cancer Currents Blog

    Science.gov (United States)

    Blog posts on cancer health disparities research—including factors that influence disparities, disparities-related research efforts, and diversity in the cancer research workforce—from NCI Cancer Currents.

  8. Cancer Technology - Cancer Currents Blog

    Science.gov (United States)

    Blog posts on technologies that affect cancer research and care—including new technologies for detecting cancer, testing treatments, storing/analyzing data, and improving patient care—from NCI Cancer Currents.

  9. Current status of pulmonary metastasectomy

    DEFF Research Database (Denmark)

    Hornbech, Kåre; Ravn, Jesper; Steinbrüchel, Daniel Andreas

    2011-01-01

    for unresected patients. In this article, we discuss the current status on pulmonary metastasectomy. Preoperative assessment and selection of surgical candidates is covered. The different surgical strategies including surgical approach, unilateral versus bilateral exploration, lymph node dissection, and repeat...

  10. Cancer Prevention - Cancer Currents Blog

    Science.gov (United States)

    A catalog of posts from NCI’s Cancer Currents blog on research related to cancer prevention. Includes posts on behavioral interventions and other ways to prevent cancer and prevention-related research programs.

  11. Marijuana: Current concepts

    Directory of Open Access Journals (Sweden)

    Donald eGreydanus

    2013-10-01

    Full Text Available Marijuana (cannabis remains a controversial drug in the 21st century. This paper considers current research on use of Cannabis sativa and its constituents such as the cannabinoids. Topics reviewed include prevalence of cannabis use, other drugs consumed with pot, the endocannabinoid system, use of medicinal marijuana, medical adverse effects of cannabis, and psychiatric adverse effects of cannabis use. Treatment of cannabis withdrawal and dependence is difficult and remains mainly based on psychological therapy; current research on pharmacologic management of problems related to cannabis consumption is also considered. The potential role of specific cannabinoids for medical benefit will be revealed as the 21st century matures. However, potential dangerous adverse effects from smoking marijuana are well known and should be clearly taught to a public often confused by a media-driven, though false message and promise of benign pot consumption.

  12. Marijuana: Current Concepts†

    Science.gov (United States)

    Greydanus, Donald E.; Hawver, Elizabeth K.; Greydanus, Megan M.; Merrick, Joav

    2013-01-01

    Marijuana (cannabis) remains a controversial drug in the twenty-first century. This paper considers current research on use of Cannabis sativa and its constituents such as the cannabinoids. Topics reviewed include prevalence of cannabis (pot) use, other drugs consumed with pot, the endocannabinoid system, use of medicinal marijuana, medical adverse effects of cannabis, and psychiatric adverse effects of cannabis use. Treatment of cannabis withdrawal and dependence is difficult and remains mainly based on psychological therapy; current research on pharmacologic management of problems related to cannabis consumption is also considered. The potential role of specific cannabinoids for medical benefit will be revealed as the twenty-first century matures. However, potential dangerous adverse effects from smoking marijuana are well known and should be clearly taught to a public that is often confused by a media-driven, though false message and promise of benign pot consumption. PMID:24350211

  13. Current practice in the management of acute/unstable slipped capital femoral epiphyses in the United Kingdom and the Netherlands: results of a survey of the membership of the British Society of Children's Orthopaedic Surgery and the Werkgroep Kinder Orthopaedie.

    Science.gov (United States)

    Witbreuk, Melinda; Besselaar, Philip; Eastwood, Deborah

    2007-03-01

    A questionnaire was sent to all members of the British Society for Children's Orthopaedic Surgery and the Werkgroep Kinder Orthopaedie to identify points of agreement/disagreement on the management of the acute unstable slip of the upper femoral epiphysis and to compare these European results with those from a similar North American survey. Sixty-five per cent responded. Overall, both countries evaluated cases similarly and believed in their urgent management. Sixty-six per cent did not reposition the slip. Significant differences were observed in attitude towards single screw usage, prophylactic pinning and metalwork removal both between the two countries and in comparison with North America.

  14. Article Including Environmental Barrier Coating System

    Science.gov (United States)

    Lee, Kang N. (Inventor)

    2015-01-01

    An enhanced environmental barrier coating for a silicon containing substrate. The enhanced barrier coating may include a bond coat doped with at least one of an alkali metal oxide and an alkali earth metal oxide. The enhanced barrier coating may include a composite mullite bond coat including BSAS and another distinct second phase oxide applied over said surface.

  15. Static, Lightweight Includes Resolution for PHP

    NARCIS (Netherlands)

    Hills, M.A.; Klint, P.; Vinju, J.J.

    2014-01-01

    Dynamic languages include a number of features that are challenging to model properly in static analysis tools. In PHP, one of these features is the include expression, where an arbitrary expression provides the path of the file to include at runtime. In this paper we present two complementary analy

  16. Cigarette makers pioneered many of our black arts of disinformation, including the funding of research to distract from the hazards of smoking. Ten Nobel prizes were the result. By funding distraction research, the cigarette industry became an important source of academic corruption, helping also to forge other forms of denialism on a global scale.

    Science.gov (United States)

    Proctor, R. N.

    2014-12-01

    Cigarette Disinformation: Origins and Global Impact Robert N. Proctor The cigarette is the deadliest artifact in the history of human civilization. And whereas "only" a hundred million people died in the 20th century from smoking, we are presently on a pace to have several times that toll in the present century. Much of that catastrophe would not be possible without a massive campaign of disinformation. The cigarette industry pioneered many of the black arts of disinformation, cleverly exploiting the inherent skepticism of science to claim that "more research" was needed to resolve a purported "cigarette controversy." Cigarette makers funded hundreds of millions of dollars worth of "distraction research," most of which was solid empirical science but off topic, focusing on basic biology and biochemistry, viral and genetic causes of disease, and other "cigarette friendly" topics. At least ten Nobel prizes were the result. Cigarette skepticism was thus more complex than we normally imagine: the tobacco industry corrupted science by funding "alternative causation," meaning anything that could be used to draw attention away from cigarettes as a source of disease. The cigarette industry by this means became the most important source of academic corruption since the Nazi era. That corruption has also helped forge other forms of denialism and corruption on a global scale.

  17. 宁夏农村面源污染现状调查分析结果初报%Preliminary Report on Investigation and Analysis Result of Current Situation of Rural Non-point Source Pol ution in Ningxia

    Institute of Scientific and Technical Information of China (English)

    杨晓娟; 靳军良; 王金保

    2014-01-01

    通过调查监测,宁夏农村面源污染的主要来源集中体现在化肥污染、农药污染、畜禽粪便污染、农膜污染及农村生活污染5个方面,但其影响和污染主要表现在对水环境和土壤环境的污染上。其中,对水环境的污染形式则是通过地表径流和地下淋溶把过剩的氮、磷、有机农药、无机盐等带到地表水和地下水中,致使地表水富营养化,破环水生态环境,鱼虾难以生存。对土壤环境的污染形式是通过农业投入品超量施入,在改变土壤物理性状、破环土壤通透性、造成土壤板结、粘结的同时,造成重金属离子和病原菌的积累,给农产品质量安全带来危害。%Based on an investigation and monitoring,the main sources of Ningxia rural non-point source pollution includes the five aspects of chemical fertilizer pollution, pesticide pollution, livestock and poultry manure pollution, agricultural plastic film pollution and rural domestic pollution. But the impact and pollution were mainly manifested in the pollution of water envi-ronment and soil environment. The form of pollution of the water environment was bringing excess nitrogen, phosphorus, or-ganic pesticides and inorganic salt to the surface water and underground water by the surface runoff and underground leach-ing,it caused the surface water eutrophication,the destruction of the aquatic ecological environment and made the fish and shrimp hard to survive. The form of pollution of the soil environment was changing the soil physical characteristic, destroying the soil permeability, causing soil compaction and bond,and causing the accumulation of heavy metal ions and pathogenic bacteria by excessive application of agricultural inputs, and it brought harms to the quality and safety of agricultural products.

  18. Galvanic cells including cobalt-chromium alloys.

    Science.gov (United States)

    Gjerdet, N R

    1980-01-01

    Galvanic cells may be created when dentures made of cobalt-chromium alloys are placed on teeth with metallic restorations. The power of such cells was evaluated in an in vitro galvanic using amalgams, gold alloy, and nickel-chromium alloys. The amalgams and one of the nickel-chromium alloys revealed high corrosion currents when placed in contact with cobalt-chromium alloy, the conventional amalgam showing the highest values. The gold alloy and another nickel-chromium alloy exhibited low corrosion currents and they were noble with respect to cobalt-chromium.

  19. Engine lubrication circuit including two pumps

    Science.gov (United States)

    Lane, William H.

    2006-10-03

    A lubrication pump coupled to the engine is sized such that the it can supply the engine with a predetermined flow volume as soon as the engine reaches a peak torque engine speed. In engines that operate predominately at speeds above the peak torque engine speed, the lubrication pump is often producing lubrication fluid in excess of the predetermined flow volume that is bypassed back to a lubrication fluid source. This arguably results in wasted power. In order to more efficiently lubricate an engine, a lubrication circuit includes a lubrication pump and a variable delivery pump. The lubrication pump is operably coupled to the engine, and the variable delivery pump is in communication with a pump output controller that is operable to vary a lubrication fluid output from the variable delivery pump as a function of at least one of engine speed and lubrication flow volume or system pressure. Thus, the lubrication pump can be sized to produce the predetermined flow volume at a speed range at which the engine predominately operates while the variable delivery pump can supplement lubrication fluid delivery from the lubrication pump at engine speeds below the predominant engine speed range.

  20. The Weak Neutral Current

    CERN Document Server

    Erler, Jens

    2013-01-01

    This is a review of electroweak precision physics with particular emphasis on low-energy precision measurements in the neutral current sector of the electroweak theory and includes future experimental prospects and the theoretical challenges one faces to interpret these observables. Within the minimal Standard Model they serve as determinations of the weak mixing angle which are competitive with and complementary to those obtained near the Z-resonance. In the context of new physics beyond the Standard Model these measurements are crucial to discriminate between models and to reduce the allowed parameter space within a given model. We illustrate this for the minimal supersymmetric Standard Model with or without R-parity.

  1. Restructuring the Public School Curriculum To Include Parenting Education Classes.

    Science.gov (United States)

    Tyree, Carolyn L.; And Others

    Although the current educational climate stresses a back-to-basics approach, there is nonetheless overwhelming evidence of a need for an appropriately structured parenting education program in the public school curriculum. Reasons for this need include the large number of teenage pregnancies and abortions. These lead teens to miss high school…

  2. Analysis of circuits including magnetic cores (MTRAC)

    Science.gov (United States)

    Hanzen, G. R.; Nitzan, D.; Herndon, J. R.

    1972-01-01

    Development of automated circuit analysis computer program to provide transient analysis of circuits with magnetic cores is discussed. Allowance is made for complications caused by nonlinearity of switching core model and magnetic coupling among loop currents. Computer program is conducted on Univac 1108 computer using FORTRAN IV.

  3. Eddy Resolving Global Ocean Prediction including Tides

    Science.gov (United States)

    2012-09-30

    Trasviña-Castro, A., Gaxiola-Castro, G., Zamudio, L., and R. Cervantes- Duarte , 2012: Net primary productivity, upwelling and coastal currents in...the Gulf of Ulloa, Baja California , Mexico, Ocean Sci., 8, 703–711, 2012, www.ocean-sci.net/8/703/2012/, doi:10.5194/os-8-703-2012. [published

  4. Current treatments for radiation retinopathy

    Energy Technology Data Exchange (ETDEWEB)

    Giuliari, Gian Paolo; Simpson, E. Rand (Princess Margaret Hospital, Univ. of Toronto, Dept. of Ophthalmology and Vision Sciences, Toronto (Canada)), e-mail: gpgiuliari@gmail.com; Sadaka, Ama (Schepens Eye Research Inst., Boston, MA (United States)); Hinkle, David M. (Massachusetts Eye Research and Surgery Institution, Cambridge, MA (United States))

    2011-01-15

    Background. To review the currently available therapeutic modalities for radiation retinopathy (RR), including newer investigational interventions directed towards specific aspects of the pathophysiology of this refractory complication. Methods. A review of the literature encompassing the pathogenesis of RR and the current therapeutic modalities available was performed. Results. RR is a chronic and progressive condition that results from exposure to any source of radiation. It might be secondary to radiation treatment of intraocular tumors such as choroidal melanomas, retinoblastomas, and choroidal metastasis, or from unavoidable exposure to excessive radiation from the treatment of extraocular tumors like cephalic, nasopharyngeal, orbital, and paranasal malignancies. After the results of the Collaborative Ocular Melanoma Study, most of the choroidal melanomas are being treated with plaque brachytherapy increasing by that the incidence of this radiation complication. RR has been reported to occur in as many as 60% of eyes treated with plaque radiation, with higher rates associated with larger tumors. Initially, the condition manifests as a radiation vasculopathy clinically seen as microaneurysms and telangiectasis, with posterior development of retinal hard exudates and hemorrhages, macular edema, neovascularization and tractional retinal detachment. Regrettably, the management of these eyes remains limited. Photodynamic therapy, laser photocoagulation, oral pentoxyphylline and hyperbaric oxygen have been attempted as treatment modalities with inconclusive results. Intravitreal injections of anti-vascular endothelial growth factor such as bevacizumab, ranibizumab and pegaptanib sodium have been recently used, also with variable results. Discussion. RR is a common vision threatening complication following radiation therapy. The available therapeutic options are limited and show unsatisfactory results. Further large investigative studies are required for developing

  5. Should Relational Aggression Be Included in DSM-V?

    Science.gov (United States)

    Keenan, Kate; Coyne, Claire; Lahey, Benjamin B.

    2008-01-01

    The study examines whether relational aggression should be included in DSM-V disruptive behavior disorders. The results conclude that some additional information is gathered from assessing relational aggression but not enough to be included in DSM-V.

  6. Should Relational Aggression Be Included in DSM-V?

    Science.gov (United States)

    Keenan, Kate; Coyne, Claire; Lahey, Benjamin B.

    2008-01-01

    The study examines whether relational aggression should be included in DSM-V disruptive behavior disorders. The results conclude that some additional information is gathered from assessing relational aggression but not enough to be included in DSM-V.

  7. Implante transcateter de valva aórtica: resultados atuais do desenvolvimento e implante de um nova prótese brasileira Transcatheter aortic valve implantation: results of the current development and implantation of a new Brazilian prosthesis

    Directory of Open Access Journals (Sweden)

    Diego Felipe Gaia

    2011-09-01

    . Minimally invasive transcatheter aortic valve implantation has emerged as an alternative, with lower morbidity and mortality. The aim of this study was clinical, safety and efficacy assessment. METHODS: Thirty-three high risk patients underwent transcatheter balloon expandable aortic valve implantation. Mean Logistic EuroScore risk was 39.30% and STS score 30.28%. Eight patients presented with dysfunctional bioprosthesis, remaining ones presented calcified aortic stenosis. Procedures were performed in a hybrid OR under fluoroscopic and echocardiography guidance. Using a left minithoracotomy the prosthesis were implanted trough the ventricular apex under rapid ventricular pacing or hemorrhagic shock. Echocardiographic and angiographic controls were performed. RESULTS: Implant was feasible in 30 cases. Three conversions occured. There was only one case of operative death. Median transvalvular aortic gradient reduced from 43.58 mmHg to 10.54 mmHg. Left ventricular function improved in the first 7 postoperative days. Paravalvular aortic regurgitation was mild and present in 30.30%. One case presented major vascular complication and another one permanent pacemaker implant. One major stroke case occurred. Overall 30-day mortality was 18.18%. CONCLUSION: The transapical implantation of catheter mounted bioprosthesis is a safe procedure with acceptable midterm results. Long term follow-up with increased sample power is mandatory in order to access hemodynamic, life quality and survival

  8. Current conveyors variants, applications and hardware implementations

    CERN Document Server

    Senani, Raj; Singh, A K

    2015-01-01

    This book serves as a single-source reference to Current Conveyors and their use in modern Analog Circuit Design. The authors describe the various types of current conveyors discovered over the past 45 years, details of all currently available, off-the-shelf integrated circuit current conveyors, and implementations of current conveyors using other, off-the-shelf IC building blocks. Coverage includes prominent bipolar/CMOS/Bi-CMOS architectures of current conveyors, as well as all varieties of starting from third generation current conveyors to universal current conveyors, their implementations and applications. •Describes all commercially available off-the-shelf IC current conveyors, as well as hardware implementations of current conveyors using other off-the-shelf ICs; • Describes numerous variants of current conveyors evolved over the past forty five years; • Describes a number of Bipolar/CMOS/Bi-CMOS architectures of current conveyors, along with their characteristic features; • Includes a comprehe...

  9. Clopidogrel Resistance: Current Issues

    Directory of Open Access Journals (Sweden)

    NS Neki

    2016-05-01

    Full Text Available Antiplatelet agents are mainly used in the prevention and management of atherothrombotic complications. Dual antiplatelet therapy, combining aspirin and clopidogrel, is the standard care for patients having acute coronary syndromes or undergoing percutaneous coronary intervention according to the current ACC/AHA and ESC guidelines. But in spite of administration of dual antiplatelet therapy, some patients develop recurrent cardiovascular ischemic events especially stent thrombosis which is a serious clinical problem. Antiplatelet response to clopidogrel varies widely among patients based on ex vivo platelet function measurements. Clopidogrel is an effective inhibitor of platelet activation and aggregation due to its selective and irreversible blockade of the P2Y12 receptor. Patients who display little attenuation of platelet reactivity with clopidogrel therapy are labeled as low or nonresponders or clopidogrel resistant. The mechanism of clopidogrel resistance remains incompletely defined but there are certain clinical, cellular and genetic factors including polymorphisms responsible for therapeutic failure. Currently there is no standardized or widely accepted definition of clopidogrel resistance. The future may soon be realised in the routine measurement of platelet activity in the same way that blood pressure, cholesterol and blood sugar are followed to help guide the therapy, thus improving the care for millions of people. This review focuses on the methods used to identify patients with clopidogrel resistance, the underlying mechanisms, metabolism, clinical significance and current therapeutic strategies to overcome clopidogrel resistance. J Enam Med Col 2016; 6(1: 38-46

  10. Shear in the tethys and the permian paleomagnetism in the Southern Alps, including new results

    NARCIS (Netherlands)

    Zijderveld, J.D.A.; Hazeu, G.J.A.; Nardin, M.; Voo, R. van der

    1970-01-01

    To verify paleomagnetic proof for megatectonic translation in the Tethys a large collection of samples from a key area, the Bolzano Quartz Porphyry Plateau in the Southern Alps, was examined. Their natural remanent magnetization was analyzed with thermal, and mainly alternating field demagnetization

  11. Operations of cleanrooms during a forest fire including protocols and monitoring results

    Science.gov (United States)

    Matheson, Bruce A.; Egges, Joanne; Pirkey, Michael S.; Lobmeyer, Lynette D.

    2012-10-01

    Contamination-sensitive space flight hardware is typically built in cleanroom facilities in order to protect the hardware from particle contamination. Forest wildfires near the facilities greatly increase the number of particles and amount of vapors in the ambient outside air. Reasonable questions arise as to whether typical cleanroom facilities can adequately protect the hardware from these adverse environmental conditions. On Monday September 6, 2010 (Labor Day Holiday), a large wildfire ignited near the Boulder, Colorado Campus of Ball Aerospace. The fire was approximately 6 miles from the Boulder City limits. Smoke levels from the fire stayed very high in Boulder for the majority of the week after the fire began. Cleanroom operations were halted temporarily on contamination sensitive hardware, until particulate and non-volatile residue (NVR) sampling could be performed. Immediate monitoring showed little, if any effect on the cleanroom facilities, so programs were allowed to resume work while monitoring continued for several days and beyond in some cases. Little, if any, effect was ever noticed in the monitoring performed.

  12. Results of a Saxitoxin Proficiency Test Including Characterization of Reference Material and Stability Studies

    Directory of Open Access Journals (Sweden)

    Kirsi Harju

    2015-11-01

    Full Text Available A saxitoxin (STX proficiency test (PT was organized as part of the Establishment of Quality Assurance for the Detection of Biological Toxins of Potential Bioterrorism Risk (EQuATox project. The aim of this PT was to provide an evaluation of existing methods and the European laboratories’ capabilities for the analysis of STX and some of its analogues in real samples. Homogenized mussel material and algal cell materials containing paralytic shellfish poisoning (PSP toxins were produced as reference sample matrices. The reference material was characterized using various analytical methods. Acidified algal extract samples at two concentration levels were prepared from a bulk culture of PSP toxins producing dinoflagellate Alexandrium ostenfeldii. The homogeneity and stability of the prepared PT samples were studied and found to be fit-for-purpose. Thereafter, eight STX PT samples were sent to ten participating laboratories from eight countries. The PT offered the participating laboratories the possibility to assess their performance regarding the qualitative and quantitative detection of PSP toxins. Various techniques such as official Association of Official Analytical Chemists (AOAC methods, immunoassays, and liquid chromatography-mass spectrometry were used for sample analyses.

  13. External Contamination Environment at ISS Included: Selected Results from Payloads Contamination Mapping Delivery 3 Package

    Science.gov (United States)

    Olsen, Randy; Huang, Alvin; Steagall, Courtney; Kohl, Nathaniel; Koontz, Steve; Worthy, Erica

    2017-01-01

    The International Space Station is the largest and most complex on-orbit platform for space science utilization in low Earth orbit. Multiple sites for external payloads, with exposure to the associated natural and induced environments, are available to support a variety of space science utilization objectives. Contamination is one of the induced environments that can impact performance, mission success and science utilization on the vehicle. The ISS has been designed, built and integrated with strict contamination requirements to provide low levels of induced contamination on external payload assets.

  14. Results on the EW gauge boson and jet production (including sensitivity to PDFs)

    CERN Document Server

    Richter-Was, Elzbieta; The ATLAS collaboration

    2017-01-01

    The production of jets in association with vector bosons is an important process to study perturbative QCD in a multi-scale environment. The LHC collaborations have performed measurements of vector boson+jets cross sections, differential in several kinematic variables, in proton-proton collision data taken at center-of-mass energies of 8TeV and 13TeV. Measurements explored also extreme phase-space: EW production and collinear W emissions. Discussed is also precise measurement of leptons angular correlations for Z+j production at high pT. The measurements are compared to state-of-the art theory predictions and can be used to constrain the proton structure. In this context discussed are also high precision measurement of the differential W and Z boson cross-sections.

  15. Optimized tracking of RF carriers with phase noise, including Pioneer 10 results

    Science.gov (United States)

    Vilnrotter, V. A.; Hurd, W. J.; Brown, D. H.

    1987-01-01

    The ability to track very weak signals from distant spacecraft is limited by the phase instabilities of the received signal and of the local oscillator employed by the receiver. These instabilities ultimately limit the minimum loop bandwidth that can be used in a phase-coherent receiver, and hence limit the ratio of received carrier power to noise spectral density which can be tracked phase coherently. A method is presented for near real time estimation of the received carrier phase and additive noise spectrum, and optimization of the phase locked loop bandwidth. The method was used with the breadboard Deep Space Network (DSN) Advanced Receiver to optimize tracking of very weak signals from the Pioneer 10 spacecraft, which is now more distant that the edge of the solar system. Tracking with bandwidths of 0.1 Hz to 1.0 Hz reduces tracking signal threshold and increases carrier loop signal to noise ratio (SNR) by 5 dB to 15 dB compared to the 3 Hz bandwidth of the receivers now used operationally in the DSN. This will enable the DSN to track Pioneer 10 until its power sources fails near the end of the century.

  16. Radiodermatitis: A Review of Our Current Understanding.

    Science.gov (United States)

    Singh, Manni; Alavi, Afsaneh; Wong, Rebecca; Akita, Sadanori

    2016-06-01

    Radiodermatitis (radiation dermatitis, radiation-induced skin reactions, or radiation injury) is a significant side effect of ionizing radiation delivered to the skin during cancer treatment as well as a result of nuclear attacks and disasters, such as that which occurred in Fukushima in 2011. More specifically, 95 % of cancer patients receiving radiation therapy will develop some form of radiodermatitis, including erythema, dry desquamation, and moist desquamation. These radiation skin reactions result in a myriad of complications, including delays in treatment, diminished aesthetic appeal, and reduced quality of life. Recent technological advancements and novel treatment regimens have only been successful in partly ameliorating these adverse side effects. This article examines the current knowledge surrounding the pathogenesis, clinical manifestations, differential diagnoses, prevention, and management of radiodermatitis. Future research should examine therapies that incorporate the current understanding of the pathophysiology of radiodermatitis while measuring effectiveness using objective and universal outcome measures.

  17. How many Chinese journals are included in the newly indexed 700 regional journals on Web of Science?

    Institute of Scientific and Technical Information of China (English)

    Xiu-fang WU; Qiang FU; Helen(Yue-hong)ZHANG

    2008-01-01

    @@ Based on the current news via Thomson Reuters "700 new regional journals in the world have been added to Web of Science since 2007", we conducted an investigation to find out that 43 (6.1%) Chinese journals (including 6 journals from Hong Kong region) are included. The results also show that up to now a total of about 153 Chinese journals (114 from China Mainland, 11 from Hong Kong and 28 from Taiwan) have been included by SCI and SSCI & AHCI.

  18. Generalized fluid theory including non-Maxwellian kinetic effects

    Energy Technology Data Exchange (ETDEWEB)

    Izacard, Olivier

    2017-03-29

    The results obtained by the plasma physics community for the validation and the prediction of turbulence and transport in magnetized plasmas come mainly from the use of very central processing unit (CPU)-consuming particle-in-cell or (gyro)kinetic codes which naturally include non-Maxwellian kinetic effects. To date, fluid codes are not considered to be relevant for the description of these kinetic effects. Here, after revisiting the limitations of the current fluid theory developed in the 19th century, we generalize the fluid theory including kinetic effects such as non-Maxwellian super-thermal tails with as few fluid equations as possible. The collisionless and collisional fluid closures from the nonlinear Landau Fokker–Planck collision operator are shown for an arbitrary collisionality. Indeed, the first fluid models associated with two examples of collisionless fluid closures are obtained by assuming an analytic non-Maxwellian distribution function (e.g. the INMDF (Izacard, O. 2016b Kinetic corrections from analytic non-Maxwellian distribution functions in magnetized plasmas.Phys. Plasmas23, 082504) that stands for interpreted non-Maxwellian distribution function). One of the main differences with the literature is our analytic representation of the distribution function in the velocity phase space with as few hidden variables as possible thanks to the use of non-orthogonal basis sets. These new non-Maxwellian fluid equations could initiate the next generation of fluid codes including kinetic effects and can be expanded to other scientific disciplines such as astrophysics, condensed matter or hydrodynamics. As a validation test, we perform a numerical simulation based on a minimal reduced INMDF fluid model. The result of this test is the discovery of the origin of particle and heat diffusion. The diffusion is due to the competition between a growing INMDF on short time scales due to spatial gradients and the thermalization on longer time

  19. Lung xenotransplantation: recent progress and current status.

    Science.gov (United States)

    Harris, Donald G; Quinn, Kevin J; Dahi, Siamak; Burdorf, Lars; Azimzadeh, Agnes M; Pierson, Richard N

    2014-01-01

    Xenotransplantation has undergone important progress in controlling initial hyperacute rejection in many preclinical models, with some cell, tissue, and organ xenografts advancing toward clinical trials. However, acute injury, driven primarily by innate immune and inflammatory responses, continues to limit results in lung xenograft models. The purpose of this article is to review the current status of lung xenotransplantation--including the seemingly unique challenges posed by this organ-and summarize proven and emerging means of overcoming acute lung xenograft injury.

  20. Recent Beijing Spectroscopy (BES) results

    Institute of Scientific and Technical Information of China (English)

    LI WeiGuo

    2008-01-01

    Recent experimental results from Beijing Spectroscopy (BES) are reviewed,in-cluding the hadron spectroscopy from J/ψdecays,and a number of new states are found or confirmed,including σ,κ;X(1835),ωψ threshold enhancement in J/ψ→γωψ,a broad resbnance in J/ψ→K+K-π0,decay studies of ψ(2S) and χCJ,as well as the results of ψ(3770) non-DD decays.The current status of BEPCⅡ/BESⅢ,the major upgrade of BEPC/BESⅡ,is also reported.

  1. Results and current trends of nuclear methods used in agriculture

    Energy Technology Data Exchange (ETDEWEB)

    Horacek, P. (Ceskoslovenska Komise pro Atomovou Energii, Prague)

    1983-11-01

    The significance is evaluated of nuclear methods for agricultural research. The number of breeds induced by radiation mutations is increasing. The main importance of radiation mutation breeding consists in obtaining sources of the desired genetic properties for further hybridization. Radiostimulation is conducted with the aim of increasing yields. The irradiation of foods has not substantially increased worldwide. Very important is the irradiation of excrements and sludges which after such inactivation of pathogenic microorganisms may be used as humus-forming manure or as feed additives. In some countries the method is successfully being used of sexual sterilization for eradication of insect pests. The application of labelled compounds in the nutrition, physiology and protection of plants, farm animals and in food hygiene makes it possible to acquire new and accurate knowledge very quickly. Radioimmunoassay is a highly promising method in this respect. Labelling compounds with the stable /sup 15/N isotope is used for the research of nitrogen metabolism.

  2. Report on results of current and future metal casting

    Energy Technology Data Exchange (ETDEWEB)

    Unal, Cetin [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Carlson, Neil N. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-09-28

    New modeling capabilities needed to simulate the casting of metallic fuels are added to Truchas code. In this report we summarize improvements we made in FY2015 in three areas; (1) Analysis of new casting experiments conducted with BCS and EFL designs, (2) the simulation of INL’s U-Zr casting experiments with Flow3D computer program, (3) the implementation of surface tension model into Truchas for unstructured mesh required to run U-Zr casting.

  3. Positron Computed Tomography: Current State, Clinical Results and Future Trends

    Science.gov (United States)

    Schelbert, H. R.; Phelps, M. E.; Kuhl, D. E.

    1980-09-01

    An overview is presented of positron computed tomography: its advantages over single photon emission tomography, its use in metabolic studies of the heart and chemical investigation of the brain, and future trends. (ACR)

  4. Lung Disease Including Asthma and Adult Vaccination

    Science.gov (United States)

    ... Healthcare Professionals Lung Disease including Asthma and Adult Vaccination Language: English Español (Spanish) Recommend on Facebook Tweet ... more about health insurance options. Learn about adult vaccination and other health conditions Asplenia Diabetes Heart Disease, ...

  5. Births and deaths including fetal deaths

    Data.gov (United States)

    U.S. Department of Health & Human Services — Access to a variety of United States birth and death files including fetal deaths: Birth Files, 1968-2009; 1995-2005; Fetal death file, 1982-2005; Mortality files,...

  6. 28 CFR 20.32 - Includable offenses.

    Science.gov (United States)

    2010-07-01

    ...., drunkenness, vagrancy, disturbing the peace, curfew violation, loitering, false fire alarm, non-specific charges of suspicion or investigation, and traffic violations (except data will be included on arrests...

  7. Including risk in the balanced scorecard

    African Journals Online (AJOL)

    kirstam

    iiSouthern African Business Review Special Edition Accounting Research 2015. Including risk in the .... customer, internal business process and learning and growth perspectives comprise ...... Boston: Harvard Business School Press. Kaplan ...

  8. Ring current and radiation belts

    Science.gov (United States)

    Williams, D. J.

    1987-01-01

    Studies performed during 1983-1986 on the ring current, the injection boundary model, and the radiation belts are discussed. The results of these studies yielded the first observations on the composition and charge state of the ring current throughout the ring-current energy range, and strong observational support for an injection-boundary model accounting for the origins of radiation-belt particles, the ring current, and substorm particles observed at R less than about 7 earth radii. In addition, the results have demonstrated that the detection of energetic neutral atoms generated by charge-exchange interactions between the ring current and the hydrogen geocorona can provide global images of the earth's ring current and its spatial and temporal evolution.

  9. Kalaeloa Energy System Redevelopment Options Including Advanced Microgrids.

    Energy Technology Data Exchange (ETDEWEB)

    Hightower, Marion Michael [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Baca, Michael J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); VanderMey, Carissa [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-03-01

    In June 2016, the Department of Energy's (DOE's) Office of Energy Efficiency and Renewable Energy (EERE) in collaboration with the Renewable Energy Branch for the Hawaii State Energy Office (HSEO), the Hawaii Community Development Authority (HCDA), the United States Navy (Navy), and Sandia National Laboratories (Sandia) established a project to 1) assess the current functionality of the energy infrastructure at the Kalaeloa Community Development District, and 2) evaluate options to use both existing and new distributed and renewable energy generation and storage resources within advanced microgrid frameworks to cost-effectively enhance energy security and reliability for critical stakeholder needs during both short-term and extended electric power outages. This report discusses the results of a stakeholder workshop and associated site visits conducted by Sandia in October 2016 to identify major Kalaeloa stakeholder and tenant energy issues, concerns, and priorities. The report also documents information on the performance and cost benefits of a range of possible energy system improvement options including traditional electric grid upgrade approaches, advanced microgrid upgrades, and combined grid/microgrid improvements. The costs and benefits of the different improvement options are presented, comparing options to see how well they address the energy system reliability, sustainability, and resiliency priorities identified by the Kalaeloa stakeholders.

  10. Worldwide epidemiology of liver hydatidosis including the Mediterranean area

    Institute of Scientific and Technical Information of China (English)

    Giuseppe Grosso; Salvatore Gruttadauria; Antonio Biondi; Stefano Marventano; Antonio Mistretta

    2012-01-01

    The worldwide incidence and prevalence of cystic echinococcosis have fallen dramatically over the past several decades.Nonetheless,infection with Echinococcus granulosus (E.granulosus) remains a major public health issue in several countries and regions,even in places where it was previously at low levels,as a result of a reduction of control programmes due to economic problems and lack of resources.Geographic distribution differs by country and region depending on the presence in that country of large numbers of nomadic or semi-nomadic sheep and goat flocks that represent the intermediate host of the parasite,and their close contact with the final host,the dog,which mostly provides the transmission of infection to humans.The greatest prevalence of cystic echinococcosis in human and animal hosts is found in countries of the temperate zones,including several parts of Eurasia (the Mediterranean regions,southern and central parts of Russia,central Asia,China),Australia,some parts of America (especially South America) and north and east Africa.Echinococcosis is currently considered an endemic zoonotic disease in the Mediterranean region.The most frequent strain associated with human cystic echinococcosis appears to be the common sheep strain (G1).This strain appears to be widely distributed in all continents.The purpose of this review is to examine the distribution of E.granulosus and the epidemiology of a re-emerging disease such as cystic echinococcosis.

  11. Extending Vulnerability Assessment to Include Life Stages Considerations

    Science.gov (United States)

    Hodgson, Emma E.; Essington, Timothy E.; Kaplan, Isaac C.

    2016-01-01

    Species are experiencing a suite of novel stressors from anthropogenic activities that have impacts at multiple scales. Vulnerability assessment is one tool to evaluate the likely impacts that these stressors pose to species so that high-vulnerability cases can be identified and prioritized for monitoring, protection, or mitigation. Commonly used semi-quantitative methods lack a framework to explicitly account for differences in exposure to stressors and organism responses across life stages. Here we propose a modification to commonly used spatial vulnerability assessment methods that includes such an approach, using ocean acidification in the California Current as an illustrative case study. Life stage considerations were included by assessing vulnerability of each life stage to ocean acidification and were used to estimate population vulnerability in two ways. We set population vulnerability equal to: (1) the maximum stage vulnerability and (2) a weighted mean across all stages, with weights calculated using Lefkovitch matrix models. Vulnerability was found to vary across life stages for the six species explored in this case study: two krill–Euphausia pacifica and Thysanoessa spinifera, pteropod–Limacina helicina, pink shrimp–Pandalus jordani, Dungeness crab–Metacarcinus magister and Pacific hake–Merluccius productus. The maximum vulnerability estimates ranged from larval to subadult and adult stages with no consistent stage having maximum vulnerability across species. Similarly, integrated vulnerability metrics varied greatly across species. A comparison showed that some species had vulnerabilities that were similar between the two metrics, while other species’ vulnerabilities varied substantially between the two metrics. These differences primarily resulted from cases where the most vulnerable stage had a low relative weight. We compare these methods and explore circumstances where each method may be appropriate. PMID:27416031

  12. Extending Vulnerability Assessment to Include Life Stages Considerations.

    Directory of Open Access Journals (Sweden)

    Emma E Hodgson

    Full Text Available Species are experiencing a suite of novel stressors from anthropogenic activities that have impacts at multiple scales. Vulnerability assessment is one tool to evaluate the likely impacts that these stressors pose to species so that high-vulnerability cases can be identified and prioritized for monitoring, protection, or mitigation. Commonly used semi-quantitative methods lack a framework to explicitly account for differences in exposure to stressors and organism responses across life stages. Here we propose a modification to commonly used spatial vulnerability assessment methods that includes such an approach, using ocean acidification in the California Current as an illustrative case study. Life stage considerations were included by assessing vulnerability of each life stage to ocean acidification and were used to estimate population vulnerability in two ways. We set population vulnerability equal to: (1 the maximum stage vulnerability and (2 a weighted mean across all stages, with weights calculated using Lefkovitch matrix models. Vulnerability was found to vary across life stages for the six species explored in this case study: two krill-Euphausia pacifica and Thysanoessa spinifera, pteropod-Limacina helicina, pink shrimp-Pandalus jordani, Dungeness crab-Metacarcinus magister and Pacific hake-Merluccius productus. The maximum vulnerability estimates ranged from larval to subadult and adult stages with no consistent stage having maximum vulnerability across species. Similarly, integrated vulnerability metrics varied greatly across species. A comparison showed that some species had vulnerabilities that were similar between the two metrics, while other species' vulnerabilities varied substantially between the two metrics. These differences primarily resulted from cases where the most vulnerable stage had a low relative weight. We compare these methods and explore circumstances where each method may be appropriate.

  13. Botrytized wines – current perspectives

    Directory of Open Access Journals (Sweden)

    Magyar I

    2016-10-01

    Full Text Available Ildikó Magyar, János Soós Department of Oenology, Institute of Viticulture and Oenology, Szent István University, Budapest, Hungary Abstract: Botrytized wines are wine specialties made of overripe grapes infected by Botrytis cinerea with the form “noble rot”. Due to the particular characteristics of the noble rotted grape, these wines (eg, Tokaji Aszú, Sauternes, Trockenbeerenauslese types, etc have many characteristic features, including higher or lower residual sugar content and unique aroma composition. The technology, biochemistry, and special characteristics of botrytized wines have been researched for a long time. This review outlines the main directions of the current studies, giving a brief overview on the recent findings. Beside the traditional wine types, noble rot is increasingly utilized in making newer sweet wine styles and straw (passito wines, which generates a series of new interesting experimental results. The fungus–grape interactions during the noble rot, the induced botrytization, the microbial communities of botrytized wines, and the volatile compounds having key roles in the distinct aroma of these wine styles are being focused on in the current studies in this field. Keywords: Botrytis, noble rot, sweet wines, passito wine, aroma

  14. Sirio.NET: A new tool for managing results in eddy current inspection of steam generators and heat exchangers; Sirio.NET: Una nueva herramienta para la gestion de resultados en las inspecciones por Corrientes Inducidas de los Generadores de Vapor y Cambiadores de Calor

    Energy Technology Data Exchange (ETDEWEB)

    Mendez, M.; Marquez, A.; Rodriguez, A. L.

    2014-07-01

    The results management and control of the inspections by currents induced of tube bundles of components such as steam generators, heat exchangers, etc., by the large volume of data generated, requires the use of highly specialized tools of information management, based on database structures. (Author)

  15. Current measurement apparatus

    Science.gov (United States)

    Umans, Stephen D.

    2008-11-11

    Apparatus and methods are provided for a system for measurement of a current in a conductor such that the conductor current may be momentarily directed to a current measurement element in order to maintain proper current without significantly increasing an amount of power dissipation attributable to the current measurement element or adding resistance to assist in current measurement. The apparatus and methods described herein are useful in superconducting circuits where it is necessary to monitor current carried by the superconducting elements while minimizing the effects of power dissipation attributable to the current measurement element.

  16. Electric Power Monthly, August 1990. [Glossary included

    Energy Technology Data Exchange (ETDEWEB)

    1990-11-29

    The Electric Power Monthly (EPM) presents monthly summaries of electric utility statistics at the national, Census division, and State level. The purpose of this publication is to provide energy decisionmakers with accurate and timely information that may be used in forming various perspectives on electric issues that lie ahead. Data includes generation by energy source (coal, oil, gas, hydroelectric, and nuclear); generation by region; consumption of fossil fuels for power generation; sales of electric power, cost data; and unusual occurrences. A glossary is included.

  17. Electrochemical cell structure including an ionomeric barrier

    Energy Technology Data Exchange (ETDEWEB)

    Lambert, Timothy N.; Hibbs, Michael

    2017-06-20

    An apparatus includes an electrochemical half-cell comprising: an electrolyte, an anode; and an ionomeric barrier positioned between the electrolyte and the anode. The anode may comprise a multi-electron vanadium phosphorous alloy, such as VP.sub.x, wherein x is 1-5. The electrochemical half-cell is configured to oxidize the vanadium and phosphorous alloy to release electrons. A method of mitigating corrosion in an electrochemical cell includes disposing an ionomeric barrier in a path of electrolyte or ion flow to an anode and mitigating anion accumulation on the surface of the anode.

  18. Simulation of vibration-induced effect on plasma current measurement using a fiber optic current sensor.

    Science.gov (United States)

    Descamps, Frédéric; Aerssens, Matthieu; Gusarov, Andrei; Mégret, Patrice; Massaut, Vincent; Wuilpart, Marc

    2014-06-16

    An accurate measurement of the plasma current is of paramount importance for controlling the plasma magnetic equilibrium in tokamaks. Fiber optic current sensor (FOCS) technology is expected to be implemented to perform this task in ITER. However, during ITER operation, the vessel and the sensing fiber will be subject to vibrations and thus to time-dependent parasitic birefringence, which may significantly compromise the FOCS performance. In this paper we investigate the effects of vibrations on the plasma current measurement accuracy under ITER-relevant conditions. The simulation results show that in the case of a FOCS reflection scheme including a spun fiber and a Faraday mirror, the error induced by the vibrations is acceptable regarding the ITER current diagnostics requirements.

  19. Saturn's Other Ring Current

    Science.gov (United States)

    Crary, F. J.

    2014-04-01

    Saturn's main rings orbit the planet within an atmosphere and ionosphere of water, oxygen and hydrogen, produced by meteoritic impacts on and ultraviolet photodesorbtion of the ring particles [Johnson et al., 2006; Luhmann et al., 2006; Tseng et al., 2010]. The neutral atmosphere itself has only been tentatively detected through ultraviolet fluorescents of OH [Hall et al., 1996] while the ionosphere was observed in situ by the Cassini spacecraft shortly after orbital insertion [Coates et al.,2005; Tokar et al. 2005, Waite et al. 2005]. Although the plasma flow velocity of this ionosphere is not well-constrained, but the close association with the rings suggests that its speed would be couppled to the keplarian velocity of the rings themselves. As a result, the motion of the plasma through Saturn's magnetic field would produce an induced voltage, oriented away from the planet outside synchronous orbit and towards the planet inside synchronous orbit. Such a potential could result in currents flowing across the ring plane and closeing along magnetic field lines and through Saturn's ionosphere at latitudes between 36o and 48o. Cassini observations of whistler-mode plasma wave emissions [Xin et al.,2006] centered on synchronous orbit (1.76 Rs, mapping to 41o latitude) have been interpreted as a product of field-aligned electron beams associated with such a current. This presentation will investigate the magnitude of these currents and the resulting Joule heating of the ionosphere. An important constraint is that no auroral ultraviolet emissions have been observed at the relevant latitudes. In contrast, Joule heating could affect infrared emissions from H3+. Variations in H3+ emission associated with Saturn's rings have been reported by O'Donoghue et al., 2013, and interpreted as a result of ring "rain", i.e. precipitating water group species from the rings which alter ionosphereic chemistry and H3+ densities. As noted by O'Donoghue et al., this interpretation may be

  20. The Case for Strategies that Include Men

    African Journals Online (AJOL)

    The Case for Strategies that Include Men. Denise M Roth and .... one set of approaches advocated using medical cri- teria to identify and ... planning, offering services for the prevention and ..... are equipped with the basic minimum needed to respond to ..... Lane SD Television minidramas: social marketing and evaluation in ...

  1. Musculoskeletal ultrasound including definitions for ultrasonographic pathology

    DEFF Research Database (Denmark)

    Wakefield, RJ; Balint, PV; Szkudlarek, Marcin

    2005-01-01

    Ultrasound (US) has great potential as an outcome in rheumatoid arthritis trials for detecting bone erosions, synovitis, tendon disease, and enthesopathy. It has a number of distinct advantages over magnetic resonance imaging, including good patient tolerability and ability to scan multiple joint...

  2. An acoustic finite element including viscothermal effects

    NARCIS (Netherlands)

    Nijhof, M.J.J.; Wijnant, Y.H.; Boer, de A.

    2007-01-01

    In acoustics it is generally assumed that viscous- en thermal boundary layer effects play a minor role in the propagation of sound waves. Hence, these effects are neglected in the basic set of equations describing the sound field. However, for geometries that include small confinements of air or thi

  3. 47 CFR 65.820 - Included items.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Included items. 65.820 Section 65.820 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) INTERSTATE RATE...) Cash working capital. The average amount of investor-supplied capital needed to provide funds for...

  4. Nuclear Chemistry: Include It in Your Curriculum.

    Science.gov (United States)

    Atwood, Charles H.; Sheline, R. K.

    1989-01-01

    Some of the topics that might be included in a nuclear chemistry section are explored. Offers radioactivity, closed shells in nuclei, energy of nuclear processes, nuclear reactions, and fission and fusion as topics of interest. Provided are ideas and examples for each. (MVL)

  5. Including the Excluded: One School for All.

    Science.gov (United States)

    EFA 2000 Bulletin, 1998

    1998-01-01

    This issue of "EFA 2000" focuses on the theme of inclusive education, i.e., including children with disabilities in general education classrooms. The cover story discusses a 1995 UNESCO survey of 63 countries that showed that integration of children with disabilities in regular schools is a declared policy in almost every country.…

  6. An Integrated Biochemistry Laboratory, Including Molecular Modeling

    Science.gov (United States)

    Hall, Adele J. Wolfson Mona L.; Branham, Thomas R.

    1996-11-01

    ) experience with methods of protein purification; (iii) incorporation of appropriate controls into experiments; (iv) use of basic statistics in data analysis; (v) writing papers and grant proposals in accepted scientific style; (vi) peer review; (vii) oral presentation of results and proposals; and (viii) introduction to molecular modeling. Figure 1 illustrates the modular nature of the lab curriculum. Elements from each of the exercises can be separated and treated as stand-alone exercises, or combined into short or long projects. We have been able to offer the opportunity to use sophisticated molecular modeling in the final module through funding from an NSF-ILI grant. However, many of the benefits of the research proposal can be achieved with other computer programs, or even by literature survey alone. Figure 1.Design of project-based biochemistry laboratory. Modules (projects, or portions of projects) are indicated as boxes. Each of these can be treated independently, or used as part of a larger project. Solid lines indicate some suggested paths from one module to the next. The skills and knowledge required for protein purification and design are developed in three units: (i) an introduction to critical assays needed to monitor degree of purification, including an evaluation of assay parameters; (ii) partial purification by ion-exchange techniques; and (iii) preparation of a grant proposal on protein design by mutagenesis. Brief descriptions of each of these units follow, with experimental details of each project at the end of this paper. Assays for Lysozyme Activity and Protein Concentration (4 weeks) The assays mastered during the first unit are a necessary tool for determining the purity of the enzyme during the second unit on purification by ion exchange. These assays allow an introduction to the concept of specific activity (units of enzyme activity per milligram of total protein) as a measure of purity. In this first sequence, students learn a turbidimetric assay

  7. Shared sanitation: to include or to exclude?

    Science.gov (United States)

    Mara, Duncan

    2016-05-01

    Just over 600 million people used shared sanitation in 2015, but this form of sanitation is not considered 'improved sanitation' or, in the current terminology, 'basic sanitation' by WHO/UNICEF, principally because they are typically unhygienic. Recent research has shown that neighbour-shared toilets perform much better than large communal toilets. The successful development of community-designed, built and managed sanitation-and-water blocks in very poor urban areas in India should be adapted and adopted throughout urban slums in developing countries, with a caretaker employed to keep the facilities clean. Such shared sanitation should be classified as 'basic', sometimes as 'safely-managed', sanitation, so contributing to the achievement of the sanitation target of the Sustainable Development Goals.

  8. Brain abscess: Current management

    Science.gov (United States)

    Alvis Miranda, Hernando; Castellar-Leones, Sandra Milena; Elzain, Mohammed Awad; Moscote-Salazar, Luis Rafael

    2013-01-01

    Brain abscess (BA) is defined as a focal infection within the brain parenchyma, which starts as a localized area of cerebritis, which is subsequently converted into a collection of pus within a well-vascularized capsule. BA must be differentiated from parameningeal infections, including epidural abscess and subdural empyema. The BA is a challenge for the neurosurgeon because it is needed good clinical, pharmacological, and surgical skills for providing good clinical outcomes and prognosis to BA patients. Considered an infrequent brain infection, BA could be a devastator entity that easily left the patient into dead. The aim of this work is to review the current concepts regarding epidemiology, pathophysiology, etiology, clinical presentation, diagnosis, and management of BA. PMID:24174804

  9. Brain abscess: Current management

    Directory of Open Access Journals (Sweden)

    Hernando Alvis-Miranda

    2013-01-01

    Full Text Available Brain abscess (BA is defined as a focal infection within the brain parenchyma, which starts as a localized area of cerebritis, which is subsequently converted into a collection of pus within a well-vascularized capsule. BA must be differentiated from parameningeal infections, including epidural abscess and subdural empyema. The BA is a challenge for the neurosurgeon because it is needed good clinical, pharmacological, and surgical skills for providing good clinical outcomes and prognosis to BA patients. Considered an infrequent brain infection, BA could be a devastator entity that easily left the patient into dead. The aim of this work is to review the current concepts regarding epidemiology, pathophysiology, etiology, clinical presentation, diagnosis, and management of BA.

  10. Sensorless Speed Control including zero speed of Non Salient PM Synchronous Drives

    DEFF Research Database (Denmark)

    Rasmussen, Henrik

    This paper presents a position sensorless drive of non salient pole PM synchronous motors for all speeds including zero speed. Using adaptive Lyapunov design a new approach for the design of an observer is developed. The resulting scheme leads to a nonlinear full order observer for the motor states...... including the rotor speed. Assuming motor parameters known the design achieves stability with guaranteed region of attraction even at zero speed. The control method is made robust at zero and low speed by changing the direct vector current component to a value different from zero. In order to verify...

  11. SKIRT: Stellar Kinematics Including Radiative Transfer

    Science.gov (United States)

    Baes, Maarten; Dejonghe, Herwig; Davies, Jonathan

    2011-09-01

    SKIRT is a radiative transfer code based on the Monte Carlo technique. The name SKIRT, acronym for Stellar Kinematics Including Radiative Transfer, reflects the original motivation for its creation: it has been developed to study the effects of dust absorption and scattering on the observed kinematics of dusty galaxies. In a second stage, the SKIRT code was extended with a module to self-consistently calculate the dust emission spectrum under the assumption of local thermal equilibrium. This LTE version of SKIRT has been used to model the dust extinction and emission of various types of galaxies, as well as circumstellar discs and clumpy tori around active galactic nuclei. A new, extended version of SKIRT code can perform efficient 3D radiative transfer calculations including a self-consistent calculation of the dust temperature distribution and the associated FIR/submm emission with a full incorporation of the emission of transiently heated grains and PAH molecules.

  12. Stochastic longshore current dynamics

    Science.gov (United States)

    Restrepo, Juan M.; Venkataramani, Shankar

    2016-12-01

    We develop a stochastic parametrization, based on a 'simple' deterministic model for the dynamics of steady longshore currents, that produces ensembles that are statistically consistent with field observations of these currents. Unlike deterministic models, stochastic parameterization incorporates randomness and hence can only match the observations in a statistical sense. Unlike statistical emulators, in which the model is tuned to the statistical structure of the observation, stochastic parametrization are not directly tuned to match the statistics of the observations. Rather, stochastic parameterization combines deterministic, i.e physics based models with stochastic models for the "missing physics" to create hybrid models, that are stochastic, but yet can be used for making predictions, especially in the context of data assimilation. We introduce a novel measure of the utility of stochastic models of complex processes, that we call consistency of sensitivity. A model with poor consistency of sensitivity requires a great deal of tuning of parameters and has a very narrow range of realistic parameters leading to outcomes consistent with a reasonable spectrum of physical outcomes. We apply this metric to our stochastic parametrization and show that, the loss of certainty inherent in model due to its stochastic nature is offset by the model's resulting consistency of sensitivity. In particular, the stochastic model still retains the forward sensitivity of the deterministic model and hence respects important structural/physical constraints, yet has a broader range of parameters capable of producing outcomes consistent with the field data used in evaluating the model. This leads to an expanded range of model applicability. We show, in the context of data assimilation, the stochastic parametrization of longshore currents achieves good results in capturing the statistics of observation that were not used in tuning the model.

  13. Rotor assembly including superconducting magnetic coil

    Energy Technology Data Exchange (ETDEWEB)

    Snitchler, Gregory L. (Shrewsbury, MA); Gamble, Bruce B. (Wellesley, MA); Voccio, John P. (Somerville, MA)

    2003-01-01

    Superconducting coils and methods of manufacture include a superconductor tape wound concentrically about and disposed along an axis of the coil to define an opening having a dimension which gradually decreases, in the direction along the axis, from a first end to a second end of the coil. Each turn of the superconductor tape has a broad surface maintained substantially parallel to the axis of the coil.

  14. Electric power monthly, September 1990. [Glossary included

    Energy Technology Data Exchange (ETDEWEB)

    1990-12-17

    The purpose of this report is to provide energy decision makers with accurate and timely information that may be used in forming various perspectives on electric issues. The power plants considered include coal, petroleum, natural gas, hydroelectric, and nuclear power plants. Data are presented for power generation, fuel consumption, fuel receipts and cost, sales of electricity, and unusual occurrences at power plants. Data are compared at the national, Census division, and state levels. 4 figs., 52 tabs. (CK)

  15. Results from the Salt Phase of SNO

    CERN Document Server

    Miknaitis, K; Ahmed, S N; Anthony, A E; Beier, E W; Bellerive, A; Bergevin, M; Biller, S D; Boger, J; Boulay, M G; Bowler, M G; Bullard, T V; Chan, Y D; Chen, M; Chen, X; Cleveland, B T; Cox, G A; Currat, C A; Dai, X; Dalnoki-Veress, F; Deng, H; Doe, P J; Dosanjh, R S; Doucas, G; Duba, C A; Duncan, F A; Dunford, M; Dunmore, J A; Earle, E D; Elliott, S R; Evans, H C; Ewan, G T; Farine, J; Fergani, H; Fleurot, F; Formaggio, J A; Frame, K; Frati, W; Fulsom, B G; Gagnon, N; Graham, K; Grant, D R; Hahn, R L; Hall, J C; Hallin, A L; Hallman, E D; Handler, W B; Hargrove, C K; Harvey, P J; Hazama, R; Heeger, K M; Heelan, L; Heintzelman, W J; Heise, J; Helmer, R L; Hemingway, R J; Hime, A; Howard, C; Howe, M A; Huang, M; Jagam, P; Jelley, N A; Klein, J R; Kormos, L L; Kos, M S; Krüger, A; Kraus, C V; Krauss, C B; Krumins, A V; Kutter, T; Kyba, C C M; Labranche, H; Lange, R; Law, J; Lawson, I T; Lesko, K T; Leslie, J R; Levine, I; Loach, J C; Luoma, S; MacLellan, R; Majerus, S; Mak, H B; Maneira, J; Marino, A D; McCauley, N; McDonald, A B; McGee, S; McGregor, G; Miin, C; Moffat, B A; Nally, C W; Neubauer, M S; Nickel, B G; Noble, A J; Norman, E B; Oblath, N S; Okada, C E; Ollerhead, R W; Orrell, J L; Oser, S M; Ouellet, C V; Peeters, S J M; Poon, A W P; Rielage, K; Robertson, B C; Robertson, R G H; Rollin, E; Rosendahl, S S E; Rusu, V L; Schwendener, M H; Seibert, S R; Simard, O; Simpson, J J; Sims, C J; Sinclair, D; Skensved, P; Smith, M W E; Starinsky, N; Stokstad, R G; Stonehill, L C; Tafirout, R; Takeuchi, Y; Tesic, G; Thomson, M; Thorman, M; Tsui, T; Van Berg, R; Van de Water, R G; Virtue, C J; Wall, B L; Waller, D; Waltham, C E; Wan Chan Tseung, H; Wark, D L; Wendland, J; West, N; Wilkerson, J F; Wilson, J R; Wittich, P; Wouters, J M; Wright, A; Yeh, M; Zuber, K

    2005-01-01

    The Sudbury Neutrino Observatory (SNO) has recently completed an analysis of data from the salt phase of the experiment, in which NaCl was added to the heavy-water neutrino target to enhance sensitivity to solar neutrinos. Results from the 391-day salt data set are summarized, including the measured solar neutrino fluxes, the electron energy spectrum from charged current interactions, and the day-night neutrino flux asymmetries. Constraints on neutrino mixing parameters including the new measurements are also given.

  16. Cryogenic current leads

    Energy Technology Data Exchange (ETDEWEB)

    Zizek, F.

    1982-01-01

    Theoretical, technical and design questions are examined of cryogenic current leads for SP of magnetic systems. Simplified mathematical models are presented for the current leads. To illustrate modeling, the calculation is made of the real current leads for 500 A and three variants of current leads for 1500 A for the enterprise ''Shkoda.''

  17. Turbidity Current Head Mixing

    Science.gov (United States)

    Hernandez, David; Sanchez, Miguel Angel; Medina, Pablo

    2010-05-01

    A laboratory experimental set - up for studying the behaviour of sediment in presence of a turbulent field with zero mean flow is compared with the behaviour of turbidity currents [1] . Particular interest is shown on the initiation of sediment motion and in the sediment lift - off. The behaviour of the turbidity current in a flat ground is compared with the zero mean flow oscilating grid generated turbulence as when wave flow lifts off suspended sediments [2,3]. Some examples of the results obtained with this set-up relating the height of the head of the turbidity current to the equilibrium level of stirred lutoclines are shown. A turbulent velocity u' lower than that estimated by the Shield diagram is required to start sediment motion. The minimum u' required to start sediment lift - off, is a function of sediment size, cohesivity and resting time. The lutocline height depends on u', and the vorticity at the lutocline seems constant for a fixed sediment size [1,3]. Combining grid stirring and turbidty current head shapes analyzed by means of advanced image analysis, sediment vertical fluxes and settling speeds can be measured [4,5]. [1] D. Hernandez Turbulent structure of turbidity currents and sediment transport Ms Thesis ETSECCPB, UPC. Barcelona 2009. [2] A. Sánchez-Arcilla; A. Rodríguez; J.C. Santás; J.M. Redondo; V. Gracia; R. K'Osyan; S. Kuznetsov; C. Mösso. Delta'96 Surf-zone and nearshore measurements at the Ebro Delta. A: International Conference on Coastal Research through large Scale Experiments (Coastal Dynamics '97). University of Plymouth, 1997, p. 186-187. [3] P. Medina, M. A. Sánchez and J. M. Redondo. Grid stirred turbulence: applications to the initiation of sediment motion and lift-off studies Physics and Chemistry of the Earth, Part B: Hydrology, Oceans and Atmosphere. 26, Issue 4, 2001, Pages 299-304 [4] M.O. Bezerra, M. Diez, C. Medeiros, A. Rodriguez, E. Bahia., A. Sanchez-Arcilla and J.M. Redondo. Study on the influence of waves on

  18. An isolated current monitor for iontophoresis.

    Science.gov (United States)

    Hauser, S E; Cohen, S A

    1976-01-01

    An inexpensive isolated current monitor has been developed as an effort to minimize stimulus artifact in experimental systems which include iontophoresis as the source of stimulus. The monitor becomes an element of the iontophoresis circuit, but provides an output voltage isolated from the iontophoresis current. The voltage is proportional to the iontophoresis current and will represent currents of 1/2 nA to 5 muA. It is this ability to detect minute currents that is valuable in iontophoresis measurements.

  19. Hyperemesis gravidarum: current aspect.

    Science.gov (United States)

    Tamay, A G; Kuşçu, N K

    2011-11-01

    An advanced state of nausea and vomiting, which are common symptoms of early pregnancy, is known as hyperemesis gravidarum and may result in dehydration, ketonuria, catabolism and require hospitalisation. Aetiological factors include increased hCG and steroids, multiple pregnancy and vitamin deficiency. Differential diagnosis of nausea and vomiting should be made and supportive treatment as well as antiemetic therapy is recommended. This review discusses aetiology and management modalities of hyperemesis gravidarum including fluid therapy, antiemetics, vitamins, psychological support and non-pharmacological measures.

  20. Current interruption transients calculation

    CERN Document Server

    Peelo, David F

    2014-01-01

    Provides an original, detailed and practical description of current interruption transients, origins, and the circuits involved, and how they can be calculated Current Interruption Transients Calculationis a comprehensive resource for the understanding, calculation and analysis of the transient recovery voltages (TRVs) and related re-ignition or re-striking transients associated with fault current interruption and the switching of inductive and capacitive load currents in circuits. This book provides an original, detailed and practical description of current interruption transients, origins,

  1. Research Results

    Science.gov (United States)

    2012-01-01

    In situ Oxidation Study of Pt (110) and Its Interaction with CO Chinese Scientists Published a Paper on Prevention of Drug Craving and Relapse by Memory Retrieval-extinction Procedure in Science Series Papers Published in Energy Policy: Modeling Energy Use of China's Road Transport and Policy Evaluation Breakthrough in the Ambient Catalytic Destruction of Formaldehyde Novel Findings for High Altitude Adaptation from the Yak Genome Binary Colloidal Structures Assembled through Ising Interactions Reemergence of superconductivity at 48K in Compressed Iron Selenide Based Superconductors Nucleosomes Suppress Spontaneous Mutations Base-Specifically in Eukaryotes Single-Chain Fragmented Antibodies Guided SiRNA Delivery in Breast Cancer Does Yeast Suicide? China Scientists Developed Important Methodologies for Spatiotemporal Detecting and Manipulating of Cellular Activities Scorpions Inspire Chinese Scientists in Making Bionic Non-eroding Surfaces for Machinery Research on Phylogenetic Placement of Borthwickia and Description of a New Family of Angiosperms, Borthwickiaceae Plasmoid Ejection and Secondary Current Sheet Generation from Magnetic Reconnection in Laser-plasma Interaction Cotton Bollworm Adapts to Bt Cotton via Diverse Mutations A Histone Acetyltransferase Regulates Active DNA Demethylation in Arabidopsis

  2. Enceladus Results

    Data.gov (United States)

    National Aeronautics and Space Administration — Here are some results from the Spectra Decomposition Algorithm on infrared spectral images of Saturn's moon Enceladus. Figure 1 is the spatial contribution of the...

  3. Including subjectivity in the teaching of Psychopathology

    Directory of Open Access Journals (Sweden)

    Octavio Domont de Serpa Junior

    2007-01-01

    Full Text Available Current psychopathology studies have often been presented in their descriptive dimension. This perspective is important for teaching because it helps the students to recognize and identify the symptomatology of each psychopathology case. However, subjectivity, the experience of suffering and interpersonal aspects are all lost in this perspective. Coming from another psychopathology tradition - existential anthropology - this paper presents practical psychopathology teaching experience which considers such dimensions as being relevant to the understanding of mental suffering. The features and limitations of such traditions are briefly reviewed to support this teaching experience. Two new modalities of practical teaching, used in the discipline of "Special Psychopathology I" offered by the Department of Psychiatry and Forensic Medicine at the medical school of the Federal University of Rio de Janeiro for students of psychology, will be presented according to descriptive case study methodology. With these activities we also expect to change the practice of teaching. Traditionally, interviewing of in-patients by a large group of students who observe passively what is happening is the center of this kind of education. We intend to develop a model of teaching which is closer to the proposal of the Brazilian Psychiatric Reform which views mental illness as a complex phenomenon, always involving the relationship that the subject establishes with the world.

  4. Including hydrological self-regulating processes in peatland models: Effects on peatmoss drought projections.

    Science.gov (United States)

    Nijp, Jelmer J; Metselaar, Klaas; Limpens, Juul; Teutschbein, Claudia; Peichl, Matthias; Nilsson, Mats B; Berendse, Frank; van der Zee, Sjoerd E A T M

    2017-02-15

    The water content of the topsoil is one of the key factors controlling biogeochemical processes, greenhouse gas emissions and biosphere - atmosphere interactions in many ecosystems, particularly in northern peatlands. In these wetland ecosystems, the water content of the photosynthetic active peatmoss layer is crucial for ecosystem functioning and carbon sequestration, and is sensitive to future shifts in rainfall and drought characteristics. Current peatland models differ in the degree in which hydrological feedbacks are included, but how this affects peatmoss drought projections is unknown. The aim of this paper was to systematically test whether the level of hydrological detail in models could bias projections of water content and drought stress for peatmoss in northern peatlands using downscaled projections for rainfall and potential evapotranspiration in the current (1991-2020) and future climate (2061-2090). We considered four model variants that either include or exclude moss (rain)water storage and peat volume change, as these are two central processes in the hydrological self-regulation of peatmoss carpets. Model performance was validated using field data of a peatland in northern Sweden. Including moss water storage as well as peat volume change resulted in a significant improvement of model performance, despite the extra parameters added. The best performance was achieved if both processes were included. Including moss water storage and peat volume change consistently reduced projected peatmoss drought frequency with >50%, relative to the model excluding both processes. Projected peatmoss drought frequency in the growing season was 17% smaller under future climate than current climate, but was unaffected by including the hydrological self-regulating processes. Our results suggest that ignoring these two fine-scale processes important in hydrological self-regulation of northern peatlands will have large consequences for projected climate change impact on

  5. The effect of Birkeland currents on magnetic field topology

    Science.gov (United States)

    Peroomian, Vahe; Lyons, Larry R.; Schulz, Michael

    1996-01-01

    A technique was developed for the inclusion of large scale magnetospheric current systems in magnetic field models. The region 1 and 2 Birkeland current systems are included in the source surface model of the terrestrial magnetosphere. The region 1 and 2 Birkeland currents are placed in the model using a series of field aligned, infinitely thin wire segments. The normal component of the magnetic field from these currents is calculated on the surface of the magnetopause and shielded using image current carrying wires placed outside of the magnetosphere. It is found that the inclusion of the Birkeland currents in the model results in a northward magnetic field in the near-midnight tail, leading to the closure of previously open flux in the tail, and a southward magnetic field in the flanks. A sunward shift in the separatrix is observed.

  6. Including students with disabilities in Learning Communities

    OpenAIRE

    2010-01-01

    Learning Communities is a project for school transformation theobjective of which is to achieve high quality education for all students, avoiding all type of segregation due to students’ level of attainment or other characteristics, and any type of differentiation or acritical adaptation of the curriculum, which may lead to unequal learning results. Students with disabilities have traditionallybeen subject to these types of practices which, nevertheless, have dubious results as far as the lea...

  7. Musculoskeletal ultrasound including definitions for ultrasonographic pathology

    DEFF Research Database (Denmark)

    Wakefield, RJ; Balint, PV; Szkudlarek, Marcin

    2005-01-01

    Ultrasound (US) has great potential as an outcome in rheumatoid arthritis trials for detecting bone erosions, synovitis, tendon disease, and enthesopathy. It has a number of distinct advantages over magnetic resonance imaging, including good patient tolerability and ability to scan multiple joints...... pathologies. This article presents the first report from the OMERACT ultrasound special interest group, which has compared US against the criteria of the OMERACT filter. Also proposed for the first time are consensus US definitions for common pathological lesions seen in patients with inflammatory arthritis....

  8. Drug delivery device including electrolytic pump

    KAUST Repository

    Foulds, Ian G.

    2016-03-31

    Systems and methods are provided for a drug delivery device and use of the device for drug delivery. In various aspects, the drug delivery device combines a “solid drug in reservoir” (SDR) system with an electrolytic pump. In various aspects an improved electrolytic pump is provided including, in particular, an improved electrolytic pump for use with a drug delivery device, for example an implantable drug delivery device. A catalytic reformer can be incorporated in a periodically pulsed electrolytic pump to provide stable pumping performance and reduced actuation cycle.

  9. Inlet Guide Vane Wakes Including Rotor Effects

    Science.gov (United States)

    Johnston, R. T.; Fleeter, S.

    2001-02-01

    Fundamental experiments are described directed at the investigation of forcing functions generated by an inlet guide vane (IGV) row, including interactions with the downstream rotor, for application to turbomachine forced response design systems. The experiments are performed in a high-speed research fan facility comprised of an IGV row upstream of a rotor. IGV-rotor axial spacing is variable, with the IGV row able to be indexed circumferentially, thereby allowing measurements to be made across several IGV wakes. With an IGV relative Mach number of 0.29, measurements include the IGV wake pressure and velocity fields for three IGV-rotor axial spacings. The decay characteristics of the IGV wakes are compared to the Majjigi and Gliebe empirical correlations. After Fourier decomposition, a vortical-potential gust splitting analysis is implemented to determine the vortical and potential harmonic wake gust forcing functions both upstream and downstream of the rotor. Higher harmonics of the vortical gust component of the IGV wakes are found to decay at a uniform rate due to viscous diffusion.

  10. Including supplementary elements in a compositional biplot

    Science.gov (United States)

    Daunis-i-Estadella, J.; Thió-Henestrosa, S.; Mateu-Figueras, G.

    2011-05-01

    The biplot is a widely and powerful methodology used with multidimensional data sets to describe and display the relationships between observations and variables in an easy way. Compositional data are vectors with positive components, whose sum is constant because they represent a relative contribution of different parts to a whole; due to this property standard biplots cannot be performed with compositional data, instead of a previous transformation of the data is performed. In this paper, we extend the compositional biplot defined by Aitchison and Greenacre (2002), in order to include in the display supplementary elements which are not used in the definition of the compositional biplot. Different types of supplementary elements are considered: supplementary parts of the composition, supplementary continuous variables external to the composition, supplementary categorical variables and supplementary observations. The projection of supplementary parts of the composition is done by means of the equivalence of clr and lr biplots. The other supplementary projections are done by classical methodology. An application example with a real geological data is included.

  11. Influence of the skin effect and current risetime on the fragmentation of wires by pulsed currents

    Science.gov (United States)

    Wall, D. P.; Allen, J. E.; Molokov, S.

    2005-07-01

    This study considers the physical phenomenon whereby wires may fragment in the solid state when subject to a sufficiently high pulsed electric current. A mathematical model is constructed within continuum mechanics which considers both Lorentz force and thermal mechanisms for the creation of stress waves in a wire. Previous studies are extended by including the skin effect, that is allowing for the diffusion of current density across the wire, and also investigating the influence of current risetime. Axisymmetric solutions are sought for rigid-lubricated, clamped, and free wire ends. Analytical solutions are obtained for the case of rigid-lubricated wire ends, while for the other cases the governing equations are solved numerically using an application-specific explicit finite-difference scheme, which is staggered in time and space. The inclusion of the skin effect leads to significant qualitative and quantitative differences in results. For example, in some cases we find tension in the longitudinal (τzz) stress component, which experiments suggest to be responsible for the fragmentation process, while the uniform-current model predicts compression. In most cases, the inclusion of the skin effect leads to higher peak tensile τzz stresses. Some understanding of the present results is gained with reference to analytical quasistatic solutions. Stresses generated by the Lorentz force mechanism are found to be more sensitive than those generated by the thermal mechanism to the current risetime. In both cases axial stresses increase with decreasing current risetime. Despite the differences in the results obtained with the inclusion of the skin effect, our results support the broad conclusions of the uniform-current model results; the largest stresses are found at the clamps for a wire with clamped ends, while the largest stresses in a wire with free ends are generated by the thermal mechanism and are located at the center of the wire.

  12. Reconnection experiments including 3D magnetic nulls

    Science.gov (United States)

    Le, A.; Egedal, J.; Vrublevskis, A.

    2010-11-01

    A rich collection of magnetic reconnection scenarios is possible in three dimensions depending on the topological and geometric structure of the magnetic field [1]. In recent experiments at the Versatile Toroidal Facility (VTF) three-dimensional effects were essential even in nearly axisymmetric plasmas with a non-vanishing toroidal field [2]. To explore reconnection in 3D geometries including magnetic null points, a new adjustable set of coils will be installed in the vacuum chamber of VTF. The range of vacuum magnetic field topologies attainable in VTF will be explored numerically. Plasma reconnection experiments will be run in these configurations, and measurements will be presented if available. [4pt] [1] CE Parnell, et al., (2009) ``Three-Dimensional Magnetic Reconnection, in Magnetic Coupling between the Interior and the Atmosphere of the Sun,'' eds. S.S. Hasan and R.J. Rutten, Springer-Verlag, Heidelberg, Berlin. [0ex] [2] Katz, N. et al., (2010) Phys. Rev. Lett. 104, 255004.

  13. Thermovoltaic semiconductor device including a plasma filter

    Science.gov (United States)

    Baldasaro, Paul F.

    1999-01-01

    A thermovoltaic energy conversion device and related method for converting thermal energy into an electrical potential. An interference filter is provided on a semiconductor thermovoltaic cell to pre-filter black body radiation. The semiconductor thermovoltaic cell includes a P/N junction supported on a substrate which converts incident thermal energy below the semiconductor junction band gap into electrical potential. The semiconductor substrate is doped to provide a plasma filter which reflects back energy having a wavelength which is above the band gap and which is ineffectively filtered by the interference filter, through the P/N junction to the source of radiation thereby avoiding parasitic absorption of the unusable portion of the thermal radiation energy.

  14. CLIC expands to include the Southern Hemisphere

    CERN Multimedia

    Roberto Cantoni

    2010-01-01

    Australia has recently joined the CLIC collaboration: the enlargement will bring new expertise and resources to the project, and is especially welcome in the wake of CERN budget redistributions following the recent adoption of the Medium Term Plan.   The countries involved in CLIC collaboration With the signing of a Memorandum of Understanding on 26 August 2010, the ACAS network (Australian Collaboration for Accelerator Science) became the 40th member of in the multilateral CLIC collaboration making Australia the 22nd country to join the collaboration. “The new MoU was signed by the ACAS network, which includes the Australian Synchrotron and the University of Melbourne”, explains Jean-Pierre Delahaye, CLIC Study Leader. “Thanks to their expertise, the Australian institutes will contribute greatly to the CLIC damping rings and the two-beam test modules." Institutes from any country wishing to join the CLIC collaboration are invited to assume responsibility o...

  15. CERN Technical Training: LABVIEW courses include RADE

    CERN Multimedia

    HR Department

    2009-01-01

    The contents of the "LabView Basic I" and "LabView Intermediate II" courses have recently been changed to include, respectively, an introduction to and expert training in the Rapid Application Development Environment (RADE). RADE is a LabView-based application developed at CERN to integrate LabView in the accelerator and experiment control infrastructure. It is a suitable solution to developing expert tools, machine development analysis and independent test facilities. The course names have also been changed to "LabVIEW Basics I with RADE Introduction" and "LabVIEW Intermediate II with Advanced RADE Application". " LabVIEW Basics I with RADE Introduction" is designed for: Users preparing to develop applications using LabVIEW, or NI Developer Suite; users and technical managers evaluating LabVIEW or NI Developer Suite in purchasing decisions; users pursuing the Certified LabVIEW Developer certification. The course pr...

  16. CERN Technical Training: LABVIEW courses include RADE

    CERN Multimedia

    HR Department

    2009-01-01

    The contents of "LabView Basic I" and "LabView Intermediate II" trainings have been recently changed to include, respectively, an introduction and an expert training on the Rapid Application Development Environment (RADE). RADE is a LabView-based application developed at CERN to integrate LabView in the accelerator and experiment control infrastructure. It is a suitable solution to develop expert tools, machine development analysis and independent test facilities. The course names have also been changed to "LabVIEW Basics I with RADE Introduction" and "LabVIEW Intermediate II with Advanced RADE Application". " LabVIEW Basics I with RADE Introduction" is designed for: Users preparing to develop applications using LabVIEW, or NI Developer Suite; users and technical managers evaluating LabVIEW or NI Developer Suite in purchasing decisions; users pursuing the Certified LabVIEW Developer certification. The course prepare...

  17. CERN Technical Training: LABVIEW courses include RADE

    CERN Multimedia

    HR Department

    2009-01-01

    The contents of the "LabView Basic I" and "LabView Intermediate II" courses have recently been changed to include, respectively, an introduction to and expert training in the Rapid Application Development Environment (RADE). RADE is a LabView-based application developed at CERN to integrate LabView in the accelerator and experiment control infrastructure. It is a suitable solution to developing expert tools, machine development analysis and independent test facilities. The course names have also been changed to "LabVIEW Basics I with RADE Introduction" and "LabVIEW Intermediate II with Advanced RADE Application". " LabVIEW Basics I with RADE Introduction" is designed for: Users preparing to develop applications using LabVIEW, or NI Developer Suite; users and technical managers evaluating LabVIEW or NI Developer Suite in purchasing decisions; users pursuing the Certified LabVIEW Developer certification. The course prepares participants to develop test and measurement, da...

  18. ACCREDITATION FOR TECHNICAL ABILITIES INCLUDING COMPUTER SKILLS

    Directory of Open Access Journals (Sweden)

    Halit Hami OZ

    2013-01-01

    Full Text Available Sector Skills are defined by state-sponsored, employer-led organizations that cover specific economic sectors in the European Union and other countries in the world to reduce skills gaps and shortages, improve productivity, boost the skills of their sector workforces and improve learning supply. The accreditation and registration systems used by professional bodies raise the profile of the profession. In many countries including the European Union, professional associations are beginning to accept practice-based accreditation, generally as an alternative to their mainstream systems. Besides studying the certain agencies in the European Union for assessing/accreditating practical abilities , Accreditation for practical abilities of Information Communication Technology and Business Management/Language domains developed by Accreditation Council for Practical abilities are also studied in detail as an example to establish a similar agency in Turkey.

  19. AMS at the ANU including biomedical applications

    Energy Technology Data Exchange (ETDEWEB)

    Fifield, L.K.; Allan, G.L.; Cresswell, R.G.; Ophel, T.R. [Australian National Univ., Canberra, ACT (Australia); King, S.J.; Day, J.P. [Manchester Univ. (United Kingdom). Dept. of Chemistry

    1993-12-31

    An extensive accelerator mass spectrometry program has been conducted on the 14UD accelerator at the Australian National University since 1986. In the two years since the previous conference, the research program has expanded significantly to include biomedical applications of {sup 26}Al and studies of landform evolution using isotopes produced in situ in surface rocks by cosmic ray bombardment. The system is now used for the measurement of {sup 10}Be, {sup 14}C, {sup 26}Al, {sup 36}Cl, {sup 59}Ni and {sup 129}I, and research is being undertaken in hydrology, environmental geochemistry, archaeology and biomedicine. On the technical side, a new test system has permitted the successful off-line development of a high-intensity ion source. A new injection line to the 14UD has been established and the new source is now in position and providing beams to the accelerator. 4 refs.

  20. Models of bovine babesiosis including juvenile cattle.

    Science.gov (United States)

    Saad-Roy, C M; Shuai, Zhisheng; van den Driessche, P

    2015-03-01

    Bovine Babesiosis in cattle is caused by the transmission of protozoa of Babesia spp. by ticks as vectors. Juvenile cattle (Babesiosis, rarely show symptoms, and acquire immunity upon recovery. Susceptibility to the disease varies between breeds of cattle. Models of the dynamics of Bovine Babesiosis transmitted by the cattle tick that include these factors are formulated as systems of ordinary differential equations. Basic reproduction numbers are calculated, and it is proved that if these numbers are below the threshold value of one, then Bovine Babesiosis dies out. However, above the threshold number of one, the disease may approach an endemic state. In this case, control measures are suggested by determining target reproduction numbers. The percentage of a particular population (for example, the adult bovine population) needed to be controlled to eradicate the disease is evaluated numerically using Columbia data from the literature.

  1. The surgery of peripheral nerves (including tumors)

    DEFF Research Database (Denmark)

    Fugleholm, Kåre

    2013-01-01

    Surgical pathology of the peripheral nervous system includes traumatic injury, entrapment syndromes, and tumors. The recent significant advances in the understanding of the pathophysiology and cellular biology of peripheral nerve degeneration and regeneration has yet to be translated into improved...... surgical techniques and better outcome after peripheral nerve injury. Decision making in peripheral nerve surgery continues to be a complex challenge, where the mechanism of injury, repeated clinical evaluation, neuroradiological and neurophysiological examination, and detailed knowledge of the peripheral...... nervous system response to injury are prerequisite to obtain the best possible outcome. Surgery continues to be the primary treatment modality for peripheral nerve tumors and advances in adjuvant oncological treatment has improved outcome after malignant peripheral nerve tumors. The present chapter...

  2. CERN Technical Training: LABVIEW courses include RADE

    CERN Multimedia

    HR Department

    2009-01-01

    The contents of the "LabView Basic I" and "LabView Intermediate II" courses have recently been changed to include, respectively, an introduction to and expert training in the Rapid Application Development Environment (RADE). RADE is a LabView-based application developed at CERN to integrate LabView in the accelerator and experiment control infrastructure. It is a suitable solution to developing expert tools, machine development analysis and independent test facilities. The course names have also been changed to "LabVIEW Basics I with RADE Introduction" and "LabVIEW Intermediate II with Advanced RADE Application". " LabVIEW Basics I with RADE Introduction" is designed for: Users preparing to develop applications using LabVIEW, or NI Developer Suite; users and technical managers evaluating LabVIEW or NI Developer Suite in purchasing decisions; users pursuing the Certified LabVIEW Developer certification. The course pr...

  3. Current limiting remote power control module

    Science.gov (United States)

    Hopkins, Douglas C.

    1990-01-01

    The power source for the Space Station Freedom will be fully utilized nearly all of the time. As such, any loads on the system will need to operate within expected limits. Should any load draw an inordinate amount of power, the bus voltage for the system may sag and disrupt the operation of other loads. To protect the bus and loads some type of power interface between the bus and each load must be provided. This interface is most crucial when load faults occur. A possible system configuration is presented. The proposed interface is the Current Limiting Remote Power Controller (CL-RPC). Such an interface should provide the following power functions: limit overloading and resulting undervoltage; prevent catastrophic failure and still provide for redundancy management within the load; minimize cable heating; and provide accurate current measurement. A functional block diagram of the power processing stage of a CL-RPC is included. There are four functions that drive the circuit design: rate control of current; current sensing; the variable conductance switch (VCS) technology; and the algorithm used for current limiting. Each function is discussed separately.

  4. Perturbation theory for intermolecular forces including exchange

    NARCIS (Netherlands)

    Lekkerkerker, H.N.W.; Laidlaw, W.G.

    1970-01-01

    Generalized solutions to the Kisenschitz and London perturbation equations are derived. It is pointed out that the results obtained in the formalisms proposed by Hirschfelder (HAV), by Hirschfelder and Silbey, by Murrell and Shaw, and by Musher and Amos are special cases of the generalized treatment

  5. The impact of triggering mechanism on flow dynamics and depositional geometry: results from an experimental study of non-conservative density currents; Influencia do mecanismo de iniciacao na dinamica dos fluxos e na geometria dos depositos gerados: observacoes obtidas a partir de estudo experimental de correntes de densidade nao-conservativas

    Energy Technology Data Exchange (ETDEWEB)

    Manica, Rafael [Rio Grande do Sul Univ., Porto Alegre (Brazil). Inst. de Pesquisas Hidraulicas. Nucleo de Estudos de Correntes de Densidade]. E-mail: rmanica@portoweb.com.br; Del Rey, Antonio Cosme; Maestri, Rogerio Dornelles; Borges, Ana Luiza de Oliveira; Viana, Adriano Roessler

    2005-05-01

    This study presents 28 physical simulations of non-conservative density currents used to evaluate their depositional patterns. Two different triggering mechanisms were used: lock gate and fluid injection. The impact of specific gravity, material type and grain size on the mixture were also checked. Dynamic and geometric features, such as head velocity and head/body height, were recorded. Results show flow velocity increase as concentration grows; deposition volumes present a general tendency to exponential decline with distance; the grain size range of the deposits decreases towards the distal portion of the channel. The results obtained have showed the efficiency of physical modeling in the study of turbidites in allowing correlations to be defined between currents and deposition patterns. (author)

  6. Current concepts in maxillofacial imaging

    Energy Technology Data Exchange (ETDEWEB)

    Boeddinghaus, Rudolf [Perth Radiological Clinic, 127 Hamersley Road, Subiaco, Western Australia 6008 (Australia)], E-mail: rboeddinghaus@perthradclinic.com.au; Whyte, Andy [Perth Radiological Clinic, 127 Hamersley Road, Subiaco, Western Australia 6008 (Australia)], E-mail: awhyte@perthradclinic.com.au

    2008-06-15

    A review of state-of-the-art maxillofacial imaging is presented. Current imaging techniques include intra-oral radiographs, dental panoramic tomography, multidetector helical computed tomography, cone-beam computed tomography (CBCT) and magnetic resonance imaging (MRI). The commonest conditions encountered in clinical radiological practice are reviewed, including maxillofacial deformities, complicated dental impactions, maxillofacial trauma, jaw lesions (cysts, neoplasms, fibro-osseous lesions (FOLs) and infections), and temporomandibular joint pathology. Pre-operative assessment for dental implant placement is also briefly reviewed.

  7. Misophonia: current perspectives

    Directory of Open Access Journals (Sweden)

    Cavanna AE

    2015-08-01

    Full Text Available Andrea E Cavanna,1–3 Stefano Seri3,4 1Department of Neuropsychiatry, Birmingham and Solihull Mental Health NHS Foundation Trust and University of Birmingham, Birmingham, 2Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, London, 3School of Life and Health Sciences, Aston Brain Centre, Wellcome Trust Laboratory for MEG Studies, Aston University, 4Children’s Epilepsy Surgery Programme, The Birmingham Children’s Hospital NHS Foundation Trust, Birmingham, UK Abstract: Misophonia is characterized by a negative reaction to a sound with a specific pattern and meaning to a given individual. In this paper, we review the clinical features of this relatively common yet underinvestigated condition, with focus on co-occurring neurodevelopmental disorders. Currently available data on the putative pathophysiology of the condition can inform our understanding and guide the diagnostic process and treatment approach. Tinnitus retraining therapy and cognitive behavior therapy have been proposed as the most effective treatment strategies for reducing symptoms; however, current treatment algorithms should be validated in large population studies. At the present stage, competing paradigms see misophonia as a physiological state potentially inducible in any subject, an idiopathic condition (which can present with comorbid psychiatric disorders, or a symptomatic manifestation of an underlying psychiatric disorder. Agreement on the use of standardized diagnostic criteria would be an important step forward in terms of both clinical practice and scientific inquiry. Areas for future research include phenomenology, epidemiology, modulating factors, neurophysiological underpinnings, and treatment trials. Keywords: misophonia, selective sound sensitivity syndrome, hyperacusis, neurodevelopmental disorders, Tourette syndrome, obsessive-compulsive spectrum

  8. Extreme geomagnetically induced currents

    Science.gov (United States)

    Kataoka, Ryuho; Ngwira, Chigomezyo

    2016-12-01

    We propose an emergency alert framework for geomagnetically induced currents (GICs), based on the empirically extreme values and theoretical upper limits of the solar wind parameters and of d B/d t, the time derivative of magnetic field variations at ground. We expect this framework to be useful for preparing against extreme events. Our analysis is based on a review of various papers, including those presented during Extreme Space Weather Workshops held in Japan in 2011, 2012, 2013, and 2014. Large-amplitude d B/d t values are the major cause of hazards associated with three different types of GICs: (1) slow d B/d t with ring current evolution (RC-type), (2) fast d B/d t associated with auroral electrojet activity (AE-type), and (3) transient d B/d t of sudden commencements (SC-type). We set "caution," "warning," and "emergency" alert levels during the main phase of superstorms with the peak Dst index of less than -300 nT (once per 10 years), -600 nT (once per 60 years), or -900 nT (once per 100 years), respectively. The extreme d B/d t values of the AE-type GICs are 2000, 4000, and 6000 nT/min at caution, warning, and emergency levels, respectively. For the SC-type GICs, a "transient alert" is also proposed for d B/d t values of 40 nT/s at low latitudes and 110 nT/s at high latitudes, especially when the solar energetic particle flux is unusually high.

  9. Including patients’ perspectives in patient information leaflets: A polyocular approach

    DEFF Research Database (Denmark)

    Fage-Butler, Antoinette Mary

    2013-01-01

    asymmetries. The paper contributes theoretically in its innovative use of perspectivist theory in relation to text, and in identifying that the insights of polyocularity could valuably inform a new health communication paradigm, as current health communication paradigms do not fully recognize patients......Existing research reveals that patients’ perspectives are missing from mandatory patient information leaflets (PILs). At the same time, there is overwhelming consensus that they should be included in this genre, and a corresponding need for potential approaches to tackle this problem. This paper......’ perspectives. Apart from its theoretical contributions, the paper includes guidelines to support the production of PILs where patients’ perspectives are included. The guidelines are informed by practices that have characterised previous polyocular communication events, as well as research into how to maximize...

  10. Currents for Arbitrary Helicity

    CERN Document Server

    Dragon, Norbert

    2016-01-01

    Using Mackey's classification of unitary representations of the Poincar\\'e group on massles states of arbitrary helicity we disprove the claim that states with helicity |h|>=1 cannot couple to a conserved current by constructing such a current.

  11. Microfluidic devices and methods including porous polymer monoliths

    Science.gov (United States)

    Hatch, Anson V; Sommer, Gregory J; Singh, Anup K; Wang, Ying-Chih; Abhyankar, Vinay V

    2014-04-22

    Microfluidic devices and methods including porous polymer monoliths are described. Polymerization techniques may be used to generate porous polymer monoliths having pores defined by a liquid component of a fluid mixture. The fluid mixture may contain iniferters and the resulting porous polymer monolith may include surfaces terminated with iniferter species. Capture molecules may then be grafted to the monolith pores.

  12. Full Boltzmann equations for leptogenesis including scattering

    CERN Document Server

    Hahn-Woernle, F; Wong, Y Y Y

    2009-01-01

    We study the evolution of a cosmological baryon asymmetry produced via leptogenesis by means of the full classical Boltzmann equations, without the assumption of kinetic equilibrium and including all quantum statistical factors. Beginning with the full mode equations we derive the usual equations of motion for the right-handed neutrino number density and integrated lepton asymmetry, and show explicitly the impact of each assumption on these quantities. For the first time, we investigate also the effects of scattering of the right-handed neutrino with the top quark to leading order in the Yukawa couplings by means of the full Boltzmann equations. We find that in our full Boltzmann treatment the final lepton asymmetry can be suppressed by as much as a factor of 1.5 in the weak wash-out regime (K1), the full Boltzmann treatment and the integrated approach give nearly identical final lepton asymmetries (within 10 % of each other at K>3). Finally, we show that the opposing effects of quantum statistics on decays/i...

  13. Odontogenic fibroma, including amyloid and ossifying variants.

    Science.gov (United States)

    Eversole, Lewis R

    2011-12-01

    Sixty-five cases of odontogenic fibroma (OdonF) are herein presented having been segregated into peripheral, extra bony tumors (n = 40) and tumors arising in bone or centrally (n = 25). All cases were characterized microscopically by a fibrous proliferation that varied within and between cases in cellularity and collagen fibril diameter, with intermixed odontogenic epithelial islands and cords. All central lesions presented as well demarcated radiolucencies and resorption of contiguous tooth roots was a common finding. These intraosseous lesions were of the WHO type; the so-called nonWHO type was excluded as all lesions with this diagnosis were devoid of an epithelial component and could be reclassified as other soft tissue fibrogenic tumors. Neither the central tumors nor the peripheral lesions recurred following enucleation/curettage, with a mean follow-up of 4 and 3.4 years respectively. Three distinct microscopic variations were encountered in this series: (1) two cases of OdonF with giant cell reaction, (2) two instances of OdonF with ossifying fibroma; and (3) four instances of OdonF with odontogenic ameloblast-associated protein (ODAM), an amyloid-like protein found deposited adjacent to epithelial cords plus CD1a+/S-100+ Langerhans dendritic cells entwined around the epithelial element. A single instance of the odontogenic fibroma-like hamartoma/enamel hypoplasia syndrome has been included in this series.

  14. The Current Conjuncture in Theory.

    Science.gov (United States)

    Sprinker, Michael

    1989-01-01

    Describes the current debate in literary study between the humanist/historicist and the anti-humanist/anti-historicist perspectives. Examines the political dimensions of this debate, including its relationship to Marxist theory and deconstruction. Asserts that literary texts are productions of ideology and that literary study should inquire into…

  15. Current Automotive Holometry Studies

    Science.gov (United States)

    Marchi, Mitchell M.; Snyder, D. S.

    1990-04-01

    Holometry studies of automotive body and powertrain components have become a very useful high resolution test methodology to knowledgeable Ford engineering personnel. Current examples of studies that represent the static or dynamic operational conditions of the automotive test component are presented. Continuous wave laser holometry, computer aided holometry (CAH) and pulsed laser holometry were the holometric techniques used to study the following subjects: (1) body in prime (BIP) vibration modes, (2) transmission flexplate stud-torque converter deformation due to engine torque pulses, (3) engine cylinder head and camshaft support structure deformation due to cylinder pressure and (4) engine connecting rod/cap lift-off. Static and dynamic component loading and laboratory techniques required to produce usable and valid test results are discussed along with possible conclusions for the engineering concerns.

  16. Including customers in health service design.

    Science.gov (United States)

    Perrott, Bruce E

    2013-01-01

    This article will explore the concept and meaning of codesign as it applies to the delivery of health services. The results of a pilot study in health codesign will be used as a research based case discussion, thus providing a platform to suggest future research that could lead to building more robust knowledge of how the consumers of health services may be more effectively involved in the process of developing and delivering the type of services that are in line with expectations of the various stakeholder groups.

  17. Controlled current inductors

    Science.gov (United States)

    Thaler, S.

    1970-01-01

    Magnetic permeability and shape of special core inserts are varied to produce desired changes in saturation characteristics of current dependent inductor, thus improving its inductance-to-current properties. Materials and saturation levels of the core pieces are selected to permit a wide variety of relationships between inductance and current.

  18. Improving Planck calibration by including frequency-dependent relativistic corrections

    CERN Document Server

    Quartin, Miguel

    2015-01-01

    The Planck satellite detectors are calibrated in the 2015 release using the "orbital dipole", which is the time-dependent dipole generated by the Doppler effect due to the motion of the satellite around the Sun. Such an effect has also relativistic time-dependent corrections of relative magnitude 10^(-3), due to coupling with the "solar dipole" (the motion of the Sun compared to the CMB rest frame), which are included in the data calibration by the Planck collaboration. We point out that such corrections are subject to a frequency-dependent multiplicative factor. This factor differs from unity especially at the highest frequencies, relevant for the HFI instrument. Since currently Planck calibration errors are dominated by systematics, to the point that polarization data is currently unreliable at large scales, such a correction can in principle be highly relevant for future data releases.

  19. Improving Planck calibration by including frequency-dependent relativistic corrections

    Science.gov (United States)

    Quartin, Miguel; Notari, Alessio

    2015-09-01

    The Planck satellite detectors are calibrated in the 2015 release using the "orbital dipole", which is the time-dependent dipole generated by the Doppler effect due to the motion of the satellite around the Sun. Such an effect has also relativistic time-dependent corrections of relative magnitude 10-3, due to coupling with the "solar dipole" (the motion of the Sun compared to the CMB rest frame), which are included in the data calibration by the Planck collaboration. We point out that such corrections are subject to a frequency-dependent multiplicative factor. This factor differs from unity especially at the highest frequencies, relevant for the HFI instrument. Since currently Planck calibration errors are dominated by systematics, to the point that polarization data is currently unreliable at large scales, such a correction can in principle be highly relevant for future data releases.

  20. Recent progress and advances in iterative software (including parallel aspects)

    Energy Technology Data Exchange (ETDEWEB)

    Carey, G.; Young, D.M.; Kincaid, D. [and others

    1994-12-31

    The purpose of the workshop is to provide a forum for discussion of the current state of iterative software packages. Of particular interest is software for large scale engineering and scientific applications, especially for distributed parallel systems. However, the authors will also review the state of software development for conventional architectures. This workshop will complement the other proposed workshops on iterative BLAS kernels and applications. The format for the workshop is as follows: To provide some structure, there will be brief presentations, each of less than five minutes duration and dealing with specific facets of the subject. These will be designed to focus the discussion and to stimulate an exchange with the participants. Issues to be covered include: The evolution of iterative packages, current state of the art, the parallel computing challenge, applications viewpoint, standards, and future directions and open problems.

  1. Including students with disabilities in Learning Communities

    Directory of Open Access Journals (Sweden)

    Silvia Molina

    2010-05-01

    Full Text Available Learning Communities is a project for school transformation theobjective of which is to achieve high quality education for all students, avoiding all type of segregation due to students’ level of attainment or other characteristics, and any type of differentiation or acritical adaptation of the curriculum, which may lead to unequal learning results. Students with disabilities have traditionallybeen subject to these types of practices which, nevertheless, have dubious results as far as the learning and social integration of these students is concerned. It is necessary to identify educational strategies which respond to the specific needs of these students within the framework of the same educational environment and the same learning objectives, as is being claimed from the inclusive education perspective. Starting from these premises, in this article we review the Learning Communities model as a school model which contributes to the inclusion of students with disabilities. Firstly, we will define the term “disability” and its educational implications as compared to other concepts which have also been usedin this field. Secondly, we describe some of the characteristics of the learning communities in relation to inclusive education and we focus particularly on the way in which the learning communities approach responds to the specific educational needs of students with disabilities. Finally, we will focus on a specific classroom practice, the interactive groups, and its contributions to the inclusion of students with disabilities.

  2. How primates (including us!) respond to inequity.

    Science.gov (United States)

    Brosnan, Sarah F

    2008-01-01

    Responding negatively to inequity is not a uniquely human trait. Some of our closest evolutionary ancestors respond negatively when treated less well than a conspecific. Comparative work between humans and other primates can help elucidate the evolutionary underpinnings of humans' social preferences. Results from studies of nonhuman primates, in particular chimpanzees and capuchin monkeys, are presented in comparison to human results that have been collected during economic game studies in humans, such as in the Ultimatum Game or Impunity Game. Among nonhuman primates, a frequent behavioral reaction to inequity is to refuse to continue the interaction. While in some cases this response appears to be caused by the inequitable distribution, in others, it seems to be caused by another individual's inequitable behavior. While these reactions are similar to those of humans, this reaction does not appear to be a sense of fairness in the way that we think of it in humans. Neither nonhuman primate species alters their behavior when they are the benefited individual, and in an experimental situation, chimpanzees do not alter their behavior to obtain food for their partner as well as for themselves. Although there are differences between human and nonhuman primate responses, such studies allow us to better understand the evolution of our own responses to inequity. Given the strong behavioral reactions that even monkeys show to inequitable treatment, it is not surprising that humans are concerned with equity. Such comparisons increase understanding of issues such as healthcare disparities in humans.

  3. New Gain Controllable Resistor-less Current-mode First Order Allpass Filter and its Application

    Directory of Open Access Journals (Sweden)

    W. Jaikla

    2012-04-01

    Full Text Available New first order allpass filter (APF in current mode, constructed from 2 CCCCTAs and grounded capacitor, is presented. The current gain and phase shift can be electronically /orthogonally controlled. Low input and high output impedances are achieved which make the circuit to be easily cascaded to the current-mode circuit without additional current buffers. The operation of the proposed filter has been verified through simulation results which confirm the theoretical analysis. The application example as current-mode quadrature oscillator with non-interactive current control for both of oscillation condition and oscillation frequency is included to show the usability of the proposed filter.

  4. Air Bag Momentum Force Including Aspiration

    Directory of Open Access Journals (Sweden)

    Guy Nusholtz

    1995-01-01

    Full Text Available A gas-jet momentum force drives the air bag into position during a crash. The magnitude of this force can change as a result of aspiration. To determine the potential magnitude of the effect on the momentum force and mass flow rate in an aspirated system, a series of experiments and simulations of those experiments was conducted. The simulation consists of a two-dimensional unsteady isentropic CFD model with special “infinite boundaries”. One of the difficulties in simulating the gas-jet behavior is determining the mass flow rate. To improve the reliability of the mass flow rate input to the simulation, a sampling procedure involving multiple tests was used, and an average of the tests was adopted.

  5. High temperature superconducting fault current limiter

    Energy Technology Data Exchange (ETDEWEB)

    Hull, John R. (Hinsdale, IL)

    1997-01-01

    A fault current limiter (10) for an electrical circuit (14). The fault current limiter (10) includes a high temperature superconductor (12) in the electrical circuit (14). The high temperature superconductor (12) is cooled below its critical temperature to maintain the superconducting electrical properties during operation as the fault current limiter (10).

  6. Inrush-Current Limiter And Bus Isolator

    Science.gov (United States)

    Dolland, Carlisle R.

    1994-01-01

    Electronic circuit protects electrical power bus and source of power against excessive current demands. Circuit intended for use with power-consuming electronic system drawing pulsed currents and including capacitor bank as low-impedance secondary source from which pulsed currents drawn.

  7. Current noise in tunnel junctions

    Energy Technology Data Exchange (ETDEWEB)

    Frey, Moritz; Grabert, Hermann [Physikalisches Institut, Universitaet Freiburg, Hermann-Herder-Strasse 3, 79104, Freiburg (Germany)

    2017-06-15

    We study current fluctuations in tunnel junctions driven by a voltage source. The voltage is applied to the tunneling element via an impedance providing an electromagnetic environment of the junction. We use circuit theory to relate the fluctuations of the current flowing in the leads of the junction with the voltage fluctuations generated by the environmental impedance and the fluctuations of the tunneling current. The spectrum of current fluctuations is found to consist of three parts: a term arising from the environmental Johnson-Nyquist noise, a term due to the shot noise of the tunneling current and a third term describing the cross-correlation between these two noise sources. Our phenomenological theory reproduces previous results based on the Hamiltonian model for the dynamical Coulomb blockade and provides a simple understanding of the current fluctuation spectrum in terms of circuit theory and properties of the average current. Specific results are given for a tunnel junction driven through a resonator. (copyright 2016 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  8. Osteomyelitis: a current challenge

    Directory of Open Access Journals (Sweden)

    Luciana Souza Jorge

    2010-06-01

    Full Text Available Over the last 30 years, the pathogenesis of osteomyelitis has almost been totally elucidated, and many factors responsible for the persistence of this infection have been identified. Numerous antimicrobial agents with distinct spectrums of action, pharmacokinetics, and pharmacodynamics have been used in its treatment. Surgical techniques, including muscle grafts, the Ilizarov technique, and antibiotic bone cements, have been applied. However, bone infections are still a challenge. Despite the importance of isolation and identification of microorganisms to determine the antimicrobial treatment of bone infections, there are few systematic national studies about the etiological profile of these diseases. This article describes the current knowledge of osteomyelitis and summarizes published national data based on the experience of different Orthopedic and Traumatology Services. In general, S. aureus was described as an important etiological agent; however, the difference in design of national studies makes a comparison between the prevalence of bone infection, the associated risk factors, and the different therapeutic approaches difficult. In conclusion, effort is necessary in order to stimulate systematic national studies in different Orthopedics and Traumatology Services to obtain a better consensus on preventive measures and therapies of bone infections.

  9. Bioartificial liver: current status.

    Science.gov (United States)

    Pless, G; Sauer, I M

    2005-11-01

    Liver failure remains a life-threatening syndrome. With the growing disparity between the number of suitable donor organs and the number of patients awaiting transplantation, efforts have been made to optimize the allocation of organs, to find alternatives to cadaveric liver transplantation, and to develop extracorporeal methods to support or replace the function of the failing organ. An extracorporeal liver support system has to provide the main functions of the liver: detoxification, synthesis, and regulation. The understanding that the critical issue of the clinical syndrome in liver failure is the accumulation of toxins not cleared by the failing liver led to the development of artificial filtration and adsorption devices (artificial liver support). Based on this hypothesis, the removal of lipophilic, albumin-bound substances, such as bilirubin, bile acids, metabolites of aromatic amino acids, medium-chain fatty acids, and cytokines, should be beneficial to the clinical course of a patient in liver failure. Artificial detoxification devices currently under clinical evaluation include the Molecular Adsorbent Recirculating System (MARS), Single-Pass Albumin Dialysis (SPAD), and the Prometheus system. The complex tasks of regulation and synthesis remain to be addressed by the use of liver cells (bioartificial liver support). The Extracorporeal Liver Assist Device (ELAD), HepatAssist, Modular Extracorporeal Liver Support system (MELS), and the Amsterdam Medical Center Bioartificial Liver (AMC-BAL) are bioartificial systems. This article gives a brief overview on these artificial and bioartificial devices and discusses remaining obstacles.

  10. Renal autotransplantation: current perspectives.

    Science.gov (United States)

    Stewart, B H; Banowsky, L H; Hewitt, C B; Straffon, R A

    1976-01-01

    Autotransplantation, with or without an extracorporeal renal operation, has been done 39 times in 37 patients. Indications for the procedure included severe ureteral injury in 4 patients, failed supravesical diversion in 2, renal carcinoma in a solitary kidney in 1, renovascular hypertension in 1 and donor arterial reconstruction before renal transplantation in 29. Success was obtained in all but 2 procedures, both of which involved previously operated kidneys with severe inflammation and adhesions involving the renal pelvis and pedicle. Based on our experience and a review of currently available literature we believe that renal autotransplantation and extracorporeal reconstruction can provide the best solution for patients with severe renovascular and ureteral disease not correctable by conventional operative techniques. The technique can be of particular value in removing centrally located tumors in solitary kidneys and in preparing donor kidneys with abnormal arteries for renal transplantation. The role of autotransplantation in the management of advanced renal trauma and calculus disease is less clear. A long-term comparison of patients treated by extracorporeal nephrolithotomy versus conventional lithotomy techniques will be necessary before a conclusion is reached in these disease categories.

  11. Wind farm power optimization including flow variability

    DEFF Research Database (Denmark)

    Herp, Jürgen; Poulsen, Uffe Vestergaard; Greiner, Martin

    2015-01-01

    an optimized wind-farm control strategy, derived from a fixed wake parameter, is facing this flow variability, the potential gain reduces to 0.3–0.5%. An omnipotent control strategy, which has real-time knowledge of the actual wake flow, would be able to increase the gain in wind-farm power to 4.9%.......A model-based optimisation approach is used to investigate the potential gain of wind-farm power with a cooperative control strategy between the wind turbines. Based on the Jensen wake model with the Katic wake superposition rule, the potential gain for the Nysted offshore wind farm is calculated...... to be 1.4–5.4% for standard choices 0.4 ≥ k ≥ 0.25 of the wake expansion parameter. Wake model fits based on short time intervals of length 15sec ≤ T ≤ 10 min within three months of data reveal a strong wake flow variability, resulting in rather broad distributions for the wake expansion parameter. When...

  12. Cryogenic Current Comparator as Low Intensity Beam Current Monitor in the CERN Antiproton Decelerators

    CERN Document Server

    Fernandes, M; Soby, L; Welsch, CP

    2013-01-01

    In the low-energy Antiproton Decelerator (AD) and the future Extra Low ENergy Antiproton (ELENA) rings at CERN, an absolute measurement of the beam intensity is essential to monitor any losses during the deceleration and cooling phases. However, existing DC current transformers can hardly reach the μA level, while at the AD and ELENA currents can be as low as 100 nA. A Cryogenic Current Comparator (CCC) based on a superconducting quantum interference device (SQUID) is currently being designed and shall be installed in the AD and ELENA machines. It should meet the following specifications: A current resolution smaller than 10 nA, a dynamic range covering currents between 100 nA and 1 mA, as well as a bandwidth from DC to 1 kHz. Different design options are being considered, including the use of low or high temperature superconductor materials, different CCC shapes and dimensions, different SQUID characteristics, as well as electromagnetic shielding requirements. In this contribution we present first results f...

  13. Nanorobotics current approaches and techniques

    CERN Document Server

    Ferreira, Antoine

    2013-01-01

    Nanorobot devices now perform a wide variety of tasks at the nanoscale in a wide variety of fields including but not limited to fields such as manufacturing, medicine, supply chain, biology, and outer space. Nanorobotics: Current Approaches and Techniques is a comprehensive overview of this interdisciplinary field with a wide ranging discussion that includes nano-manipulation and industrial nanorobotics, nanorobotics in biology and medicine, nanorobotic sensing, navigation and swarm behavior, and protein and DNA-based nanorobotics. Also included is the latest on topics such as bio-nano-actuators and propulsion and navigation of nanorobotic systems using magnetic fields. Nanorobotics: Current Approaches and Techniques is an ideal book for scientists, researchers, and engineers actively involved in applied and robotic research and development.

  14. Impact of Negative Sequence Current Injection by Wind Power Plants

    DEFF Research Database (Denmark)

    Chaudhary, Sanjay; Göksu, Ömer; Teodorescu, Remus;

    2013-01-01

    This paper presents an analysis of the impact from negative sequence current injection by wind power plants in power systems under steady-state and short-term unbalanced conditions, including faults. The separate positive and negative sequence current control capability of the grid-side converters...... of full scale converter type wind turbines may be utilized to alter voltage imbalance at the point of connection and further into the grid, in turn changing the resultant negative sequence current flow in the grid. The effects of such control actions have been analyzed and discussed through theoretical...

  15. Displacement currents in geoelectromagnetic problems

    Science.gov (United States)

    Mogilatov, Vladimir; Goldman, Mark; Persova, Marina; Soloveichik, Yury

    2014-06-01

    The influence of displacement currents in conventional geoelectromagnetic (GEM) methods using unimodal transversal electric (TE) or multimodal TE and TM (transversal magnetic) fields is only significant at very high frequencies in the frequency domain or at extremely early times in the time domain. The transient process in the latter includes three stages: the propagation through air, the propagation through earth and the diffusion within the earth. The influence of displacement currents is significant mainly during the former two stages, normally up to several tens to a few hundreds of nanoseconds. The behavior is essentially different in novel GEM methods using a vertical electric dipole (VED) or circular electric dipole (CED) sources of unimodal TM-fields. Under certain geoelectric conditions, the influence of displacement currents in these methods might be crucial at late times as well. This happens, if the model consists of insulating layers. In the absence of displacement currents, such layers would totally mask underlying structures. However, TM-fields including displacement currents depend on geoelectric parameters below insulating layers at late times.

  16. Current-induced dynamics in carbon atomic contacts

    DEFF Research Database (Denmark)

    Lu, Jing Tao; Gunst, Tue; Brandbyge, Mads

    2011-01-01

    voltage, which can be used to explore current-induced vibrational instabilities due the NC/BP forces. Furthermore, using tight-binding and the Brenner potential we illustrate how Langevin-type molecular-dynamics calculations including the Joule heating effect for the carbon-chain systems can be performed...... of molecular-scale contacts. Systems based on molecules bridging electrically gated graphene electrodes may offer an interesting test-bed for these effects. Results: We employ a semi-classical Langevin approach in combination with DFT calculations to study the current-induced vibrational dynamics of an atomic...... carbon chain connecting electrically gated graphene electrodes. This illustrates how the device stability can be predicted solely from the modes obtained from the Langevin equation, including the current-induced forces. We point out that the gate offers control of the current, independent of the bias...

  17. Seepage Model for PA Including Dift Collapse

    Energy Technology Data Exchange (ETDEWEB)

    G. Li; C. Tsang

    2000-12-20

    The purpose of this Analysis/Model Report (AMR) is to document the predictions and analysis performed using the Seepage Model for Performance Assessment (PA) and the Disturbed Drift Seepage Submodel for both the Topopah Spring middle nonlithophysal and lower lithophysal lithostratigraphic units at Yucca Mountain. These results will be used by PA to develop the probability distribution of water seepage into waste-emplacement drifts at Yucca Mountain, Nevada, as part of the evaluation of the long term performance of the potential repository. This AMR is in accordance with the ''Technical Work Plan for Unsaturated Zone (UZ) Flow and Transport Process Model Report'' (CRWMS M&O 2000 [153447]). This purpose is accomplished by performing numerical simulations with stochastic representations of hydrological properties, using the Seepage Model for PA, and evaluating the effects of an alternative drift geometry representing a partially collapsed drift using the Disturbed Drift Seepage Submodel. Seepage of water into waste-emplacement drifts is considered one of the principal factors having the greatest impact of long-term safety of the repository system (CRWMS M&O 2000 [153225], Table 4-1). This AMR supports the analysis and simulation that are used by PA to develop the probability distribution of water seepage into drift, and is therefore a model of primary (Level 1) importance (AP-3.15Q, ''Managing Technical Product Inputs''). The intended purpose of the Seepage Model for PA is to support: (1) PA; (2) Abstraction of Drift-Scale Seepage; and (3) Unsaturated Zone (UZ) Flow and Transport Process Model Report (PMR). Seepage into drifts is evaluated by applying numerical models with stochastic representations of hydrological properties and performing flow simulations with multiple realizations of the permeability field around the drift. The Seepage Model for PA uses the distribution of permeabilities derived from air injection testing in

  18. Equatorial potassium currents in lenses.

    Science.gov (United States)

    Wind, B E; Walsh, S; Patterson, J W

    1988-02-01

    Earlier work with the vibrating probe demonstrated the existence of outward potassium currents at the equator and inward sodium currents at the optical poles of the lens. By adding microelectrodes to the system, it is possible to relate steady currents (J) to the potential difference (PD) measured with a microelectrode. By injecting an outward current (I), it is possible to determine resistances and also the PD at which the steady outward potassium current becomes zero (PDJ = 0). At this PD the concentration gradient for potassium efflux and the electrical gradient for potassium influx are balanced so that there is no net flow of potassium across the membranes associated with the production of J. The PDJ = 0 for 18 rat lenses was 86 mV and that for 12 frogs lenses was -95 mV. This agrees with the potassium equilibrium potential and provides strong evidence to support the view that the outward equatorial current, J, is a potassium current. With the injection of outward current, I, the PD becomes more negative, the outward equatorial current, J, decreases, and the inward current at the optical poles increases. This suggests that there are separate electrical loops for K+ and Na+ that are partially linked by the Na, K-pump. Using Ohm's law, it is possible to calculate the input resistance (R = delta PD/I), the resistance related to the production of J (RJ = delta PD/delta J), and the effect of the combined resistances (delta J/I). The driving force for J can be estimated (PDJ = 0-PD). The relationships among currents, voltages and resistance can be used to determine the characteristics of the membranes that are associated with the outward potassium current observed at the equator. The effects of graded deformation of the lens were determined. The effects were reversible. The sites of inward and outward currents were not altered. Following deformation, the equatorial current, J, increased, and the PD became less negative. The PDJ = 0 remains the same so the ratio of K

  19. Current concepts in dystrophinopathies.

    Science.gov (United States)

    Viswanathan, Venkataraman

    2015-02-01

    Dystrophinopathies comprise a group of hereditary muscle disorders characterized by progressive wasting and weakness of skeletal muscle, as a result of degeneration of muscle fibers, and can be distinguished by the mode of transmission, age at onset and pattern of muscle weakness. The range of phenotypes associated with the region Xp21 has been expanding since identification of the gene in 1987. The mild end of the spectrum includes the phenotype of the muscle cramps with myoglobinuria and isolated quadriceps myopathy, while at the severe end, there are progressive muscle diseases that are classified as Duchenne / Becker muscular dystrophy (DMD/BMD).

  20. Current trends in minilaparoscopy.

    Science.gov (United States)

    Small Layne, Alyssa; Pinkard, Lauren; Shepherd, Jessica

    2016-08-01

    The purpose of this review is to understand the current use of minilaparoscopy in the field and how minilaparoscopy compares with traditional laparoscopy in terms of operative times, complications, pain, and cosmesis. Although there are few randomized controlled trials comparing minilaparoscopy with traditional laparoscopy in gynecologic procedures, the results suggest that minilaparoscopy can be performed safely with improved cosmetic outcomes and similar complication rates and operating times. Postoperative pain may be decreased with minimizing incisions sizes. Recently, case reports and case series have been published demonstrating the use of minilaparoscopy across many subtypes of gynecologic surgery. Traditional laparoscopic surgery has become common practice in gynecology as it has been found to be a well tolerated procedure with improved outcomes and decreased morbidity when compared with laparotomy. Although minilaparoscopy has been used for over 2 decades, its role in gynecology is continuing to evolve. Minilaparoscopy is a growing surgical option in gynecology as we try to minimize the impact of surgery. Results of minilaparoscopy in gynecology mirror those found in urology and general surgery. Although research is limited, minilaparoscopy has proven to be a well tolerated alternative for gynecology.