WorldWideScience

Sample records for current research suggests

  1. Gifted Male Readers: Current Understandings and Suggestions for Future Research

    Science.gov (United States)

    Pagnani, Alexander R.

    2013-01-01

    Research literature concerning gifted male readers relies primarily on more extensive bodies of work regarding gifted males and male readers. Studied as a whole, the two halves portray a worrisome state of affairs for gifted male readers, who lag behind their female counterparts in the same patterns found across the ability spectrum. This literacy…

  2. Debating Curricular Strategies for Teaching Statistics and Research Methods: What Does the Current Evidence Suggest?

    Science.gov (United States)

    Barron, Kenneth E.; Apple, Kevin J.

    2014-01-01

    Coursework in statistics and research methods is a core requirement in most undergraduate psychology programs. However, is there an optimal way to structure and sequence methodology courses to facilitate student learning? For example, should statistics be required before research methods, should research methods be required before statistics, or…

  3. Debating Curricular Strategies for Teaching Statistics and Research Methods: What Does the Current Evidence Suggest?

    Science.gov (United States)

    Barron, Kenneth E.; Apple, Kevin J.

    2014-01-01

    Coursework in statistics and research methods is a core requirement in most undergraduate psychology programs. However, is there an optimal way to structure and sequence methodology courses to facilitate student learning? For example, should statistics be required before research methods, should research methods be required before statistics, or…

  4. Research Suggestions for Students

    Science.gov (United States)

    Holland, John L.

    1974-01-01

    Describes how to perform accurate research. Also includes suggestions for specific research projects under such headings as: (1) types; (2) environments; (3) interactions; (4) classification; (5) hexagonal model; and (6) differentiation. (HMV)

  5. Photocatalytic effects of titanium dioxide nanoparticles on aquatic organisms-Current knowledge and suggestions for future research.

    Science.gov (United States)

    Haynes, Vena N; Ward, J Evan; Russell, Brandon J; Agrios, Alexander G

    2017-04-01

    Nanoparticles are entering natural systems through product usage, industrial waste and post-consumer material degradation. As the production of nanoparticles is expected to increase in the next decade, so too are predicted environmental loads. Engineered metal-oxide nanomaterials, such as titanium dioxide, are known for their photocatalytic capabilities. When these nanoparticles are exposed to ultraviolet radiation in the environment, however, they can produce radicals that are harmful to aquatic organisms. There have been a number of studies that have reported the toxicity of titanium dioxide nanoparticles in the absence of light. An increasing number of studies are assessing the interactive effects of nanoparticles and ultraviolet light. However, most of these studies neglect environmentally-relevant experimental conditions. For example, researchers are using nanoparticle concentrations and light intensities that are too high for natural systems, and are ignoring water constituents that can alter the light field. The purpose of this review is to summarize the current knowledge of the photocatalytic effects of TiO2 nanoparticles on aquatic organisms, discuss the limitations of these studies, and outline environmentally-relevant factors that need to be considered in future experiments. Copyright © 2017 Elsevier B.V. All rights reserved.

  6. Effects of soil rewetting and thawing on soil gas fluxes: a review of current literature and suggestions for future research

    Directory of Open Access Journals (Sweden)

    D.-G. Kim

    2011-10-01

    Full Text Available The rewetting of dry soils and the thawing of frozen soils are short-term, transitional phenomena in terms of hydrology and the thermodynamics of soil systems. The impact of these short-term phenomena on larger scale ecosystem fluxes has only recently been fully appreciated, and a growing number of studies show that these events affect various biogeochemical processes including fluxes of soil gases such as carbon dioxide (CO2, methane (CH4, nitrous oxide (N2O, ammonia (NH3 and nitric oxide (NO. Global climate models predict that future climatic change is likely to alter the frequency and intensity of drying-rewetting events and thawing of frozen soils, highlighting the importance of understanding how rewetting and thawing will influence soil gas fluxes. Here we summarize findings in a new database based on 338 studies conducted from 1956 to 2010, and highlight open research questions. The database revealed conflicting results following rewetting and thawing in various terrestrial ecosystems, ranging from large increases in gas fluxes to non-significant changes. An analysis of published field studies (n = 142 showed that after rewetting or thawing, CO2, CH4, N2O, NO and NH3 fluxes increase from pre-event fluxes following a power function, with no significant differenced among gases. We discuss possible mechanisms and controls that regulate flux responses, and note that a high temporal resolution of flux measurements is critical to capture rapid changes in gas fluxes after these soil perturbations. Finally, we propose that future studies should investigate the interactions between biological (i.e. microbial community and gas production and physical (i.e. flux, diffusion, dissolution changes in soil gas fluxes, and explore synergistic experimental and modelling approaches.

  7. Suggestions for Structuring a Research Article

    Science.gov (United States)

    Klein, James D.; Reiser, Robert A.

    2014-01-01

    Researchers often experience difficulty as they attempt to prepare journal articles that describe their work. The purpose of this article is to provide researchers in the field of education with a series of suggestions as to how to clearly structure each section of a research manuscript that they intend to submit for publication in a scholarly…

  8. Qualitative Research Articles: Guidelines, Suggestions and Needs

    Science.gov (United States)

    Crescentini, Alberto; Mainardi, Giuditta

    2009-01-01

    Purpose: The purpose of this paper is to give ideas and suggestions to avoid some typical problems of qualitative articles. The aim is not to debate quality in qualitative research but to indicate some practical solutions. Design/methodology/approach: The paper discusses the design of qualitative research and the structure of a qualitative article…

  9. Current and Suggested focus on Sustainability in Pyrometallurgy

    Science.gov (United States)

    See, J. B.; Robertson, D. G. C.; Mackey, P. J.

    The production of iron and steel and non-ferrous metals by pyrometallurgical processes will remain a critical element in meeting the demand for materials in both developed and developing nations. Given the important need to reduce and minimise greenhouse gas emissions the technological focus of future pyrometallurgical R&D by universities and industry alike must concentrate on sustainability issues such as improved energy efficiency, recycling and waste minimization. Continued efforts are also needed on process optimization and new process development with a view to reducing capital and operating costs of the new large "mega" plants. Using the academic and industrial backgrounds of the authors, the present paper reviews the current status of R&D in pyrometallurgy in university departments with a particular emphasis on sustainability issues. The role of industry and government laboratories is also reviewed although primarily for developed countries. The paper also includes comments and suggestions on the future requirements for education and R&D in pyrometallurgy in developed countries to maximise sustainability. It is also suggested that future R&D in pyrometallurgy will be even more concentrated in developing countries — most notably China.

  10. Current Situation in Vocational Schools: Issues and Some Suggested Solutions

    Directory of Open Access Journals (Sweden)

    Reha Metin ALKAN

    2014-12-01

    Full Text Available Vocational Schools which have undertaken various missions throughout history were established in order to train intermediate staff s with suff icient knowledge and skills in their fields, in accordance with the requirements of trade, industry and services sectors and they are the most important components of ‘vocational and technical education system' today. Analyzing the education given in the vocational schools in accordance with the national and international requirements, developing technologies and the needs of business world and making the necessary arrangements in line with these will contribute to the employability and preferability of graduates of these schools in an eff icient way. Many industrialists/businessmen in our country stated that they experienced serious problems in the supply of qualified staff with suff icient knowledge and skills needed in sectors. Although much progress has been achieved in this subject, it is a fact that there are still a lot of work to be done. In this study, current situation and main troubles in vocational schools are discussed in the light of the experiences gained at Hitit University Vocational School which was established about 40 years ago in Çorum and which is one of the first high schools in Turkey and some solutions are suggested in accordance with the problems mentioned.

  11. The Current State of China's Freshwater Resources and Related Suggestions

    Institute of Scientific and Technical Information of China (English)

    Wu Ruijin

    2001-01-01

    China has many lakes, marshlands and rivers. Due to their uneven geographical distribution and varied degrees of salinity, their exploitable freshwater resources are limited. In the wake of the highspeed growth of national economy in recent years, human infringement upon their natural settings has been increasingly intense, leading to the degeneration of China's lacustrine ecosystems and the degradation of their surrounding environments. Lakes are shrinking and becoming more saline. In arid and semi-arid inland areas, some of them have even disappeared. In addition, lake water pollution and eutrophication in densely populated areas are getting worse, resulting in serious water shortages in some places. Silt deposition in lake basins, water surface shrinkage caused by hectic and irrational reclamation for farmland, the prevalence of flooding and water-logging calamities and ecosystem depletion caused by predatory exploitation of fishery resources, all of these have become restrictive factors in regional sustainable development. The author of this article suggests measures for the protection and sustainable exploitation of limnetic settings in China.

  12. Current Solid Mechanics Research

    DEFF Research Database (Denmark)

    Tvergaard, Viggo

    2016-01-01

    About thirty years ago James Lighthill wrote an essay on “What is Mechanics?” With that he also included some examples of the applications of mechanics. While his emphasis was on fluid mechanics, his own research area, he also included examples from research activities in solid mechanics....

  13. Current Research Activities.

    Science.gov (United States)

    1975-02-01

    Biological oceanography, marine food chain dynamics, carbon cycling in the ocean. Martin, Seelye,Ph.D., Johns Hopkins. Geophysical fluid dynamics...currently under investigation, (Ahmed, Packard) 8. Amylase studies An assay for amylase activity has been adapted to measure zooplankton grazing. This...as a function of available food and of the biomass of copepods, was prescribed by sixteen equations: five, corresponding to copepodite stages (I to V

  14. 我国新修订GMP认证的现状、困境及对策研究%Research on current situation,difficulties and specific suggestions of certification of the new version of GMP

    Institute of Scientific and Technical Information of China (English)

    颜建周; 邵蓉

    2014-01-01

    This paper analyzed the current situation of GMP certification,concluding the difficulties and problems in certification process in terms of certification concepts,costs,financial sources and related mechanisms,providing specific suggestions on the basis of representative provinces such as Shandong. Suggested that we should change the enterprises′ negative attitude toward GMP certifica-tion,accelerate certification process;broaden financial sources to relieve the fund pressure of enterprises;set up full-time GMP inspec-tors pool to improve the efficiency of certification;perfect market withdrawal mechanism to eliminate the worries of enterprises.%本文在分析我国新修订GMP认证工作现状的基础上,从认证理念、认证成本、融资渠道和认证配套机制等方面总结了当前新修订GMP认证中遇到的困境。以此为依据,结合山东等典型省份的实践经验提出转变企业消极对待新修订GMP认证的观念,加快认证进度;开拓融资渠道,缓解企业认证资金压力;设置专职的GMP检查员队伍,提高认证效率;健全市场退出机制,消除拟退出企业后顾之忧等推进我国新修订GMP认证工作的政策建议。

  15. Sexual health and older adults: suggestions for social science research.

    Science.gov (United States)

    Hinchliff, Sharron

    2016-11-01

    The body of evidence on older adults' sexual health is beginning to grow. However, it remains an under-researched area particularly within the social sciences. This viewpoint outlines four considerations for those who carry out social science research in this area: 1. defining the age category "older adults"; 2. being clear about the types of sex under research; 3. capturing a range of diverse voices; and 4. considering the use of qualitative research methods to explore the topic in depth. These suggestions are aimed at helping researchers to avoid some of the pitfalls of research in this area, as well as improving the evidence base in order to advance recognition of the issues and drive change in service provision.

  16. Autocomplete as Research Tool: A Study on Providing Search Suggestions

    Directory of Open Access Journals (Sweden)

    David Ward

    2012-12-01

    Full Text Available As the library website and on its online searching tools become the primary “branch” many users visit for their research, methods for providing automated, context-sensitive research assistance need to be developed to guide unmediated searching towards the most relevant results.  This study examines one such method, the use of autocompletion in search interfaces, by conducting usability tests on its use in typical academic research scenarios.  The study reports notable findings on user preference for autocomplete features, and suggests best practices for their implementation.

  17. Research Directions Suggested by the A.C.L.U.

    Science.gov (United States)

    Triandis, Harry C.

    1975-01-01

    Translates questions submitted by Alan Reitman, Associate Executive Director of the American Civil Liberties Union which the practitioners of civil liberties would like behavioral scientists to answer into researchable topics. Reviews some of the literature relevant to each, and suggests the kinds of studies needed to provide some answers.…

  18. Children's suggestibility research: Things to know before interviewing a child

    Directory of Open Access Journals (Sweden)

    Amelia Courtney Hritz

    2015-01-01

    Full Text Available Children's testimony is often the only evidence of alleged abuse. Thus, the importance of conducting forensic interviews that are free from bias and misleading information is immense, as these could lead to false reports. In the current paper, we review unexpected findings in children's suggestibility that illustrate the difficulty in distinguishing between false and accurate reports. We explore situations in which a younger person's memory account may be more accurate than that of an adult, when a single suggestive interview may be as detrimental as multiple interviews, and when children can make inaccurate reports spontaneously. We conclude with recommendations for interviewers to decrease false reporting by both children and adults.

  19. Solid-State Lighting 2017 Suggested Research Topics

    Energy Technology Data Exchange (ETDEWEB)

    None

    2017-09-29

    A 2017 update to the Solid-State Lighting R&D Plan that is divided into two documents. The first document describes a list of suggested SSL priority research topics and the second document provides context and background, including information drawn from technical, market, and economic studies. Widely referenced by industry and government both here and abroad, these documents reflect SSL stakeholder inputs on key R&D topics that will improve efficacy, reduce cost, remove barriers to adoption, and add value for LED and OLED lighting solutions over the next three to five years, and discuss those applications that drive and prioritize the specific R&D.

  20. Six Suggestions for Research on Games in Cognitive Science.

    Science.gov (United States)

    Chabris, Christopher F

    2017-04-01

    Games are more varied and occupy more of daily life than ever before. At the same time, the tools available to study game play and players are more powerful than ever, especially massive data sets from online platforms and computational engines that can accurately evaluate human decisions. This essay offers six suggestions for future cognitive science research on games: (1) Don't forget about chess, (2) Look beyond action games and chess, (3) Use (near)-optimal play to understand human play and players, (4) Investigate social phenomena, (5) Raise the standards for studies of games as treatments, (6) Talk to real experts. Copyright © 2017 Cognitive Science Society, Inc.

  1. Current issues with research support

    Energy Technology Data Exchange (ETDEWEB)

    Russell, W.T.

    1996-03-01

    It would be difficult to condense current issues in nuclear reactor regulation to just a few minutes. So, let me start off by saying that I have not tried to give a comprehensive listing of issues that are currently facing the reactor program, but rather to select those that I thought were relevant as they relate to research activities. Use of probabilistic risk assessment in regulatory decisions; materials aging issues concerning steam generators and reactor vessels; high burnup fuels; accident management; and digital instrumentation and control, are just a sampling of the important issues that I want to talk about.

  2. Social networks user: current research

    Directory of Open Access Journals (Sweden)

    Agadullina E.R.

    2015-12-01

    Full Text Available The purpose of this article is to review current research studies focusing on the users of Facebook and their behaviors in social networks. This review is organized into two sections: 1 social-demographic characteristics (Age, Gender, Nationality; 2 personality characteristics (Neuroticism, Extraversion, Openness-to-Experience, Agreeableness, Conscientiousness, Narcissism, Self-esteem. The results showed that the information in the personal profile and online behavior are strongly connected with socio-demographic and personality characteristics

  3. Topics in current aerosol research

    CERN Document Server

    Hidy, G M

    1971-01-01

    Topics in Current Aerosol Research deals with the fundamental aspects of aerosol science, with emphasis on experiment and theory describing highly dispersed aerosols (HDAs) as well as the dynamics of charged suspensions. Topics covered range from the basic properties of HDAs to their formation and methods of generation; sources of electric charges; interactions between fluid and aerosol particles; and one-dimensional motion of charged cloud of particles. This volume is comprised of 13 chapters and begins with an introduction to the basic properties of HDAs, followed by a discussion on the form

  4. Current Situation and Suggestions of Decorative Fishery Development in Hainan Province

    Institute of Scientific and Technical Information of China (English)

    Xi; ZHANG; Ning; YANG; Hai; HUANG

    2013-01-01

    Decorative fishery is an important part of recreational fisheries,Hainan has the potential to develop decorative fishery.In this paper,on the basis of the deep-going survey on the current situation of decorative fishery development in Hainan,the main questions of decorative fish cultivation and market were discussed.At the same time,many suggestions were brought up,such as exploiting the biological resources of Hainan Island,strengthening scientific research efforts,introducing new varieties of ornamental species,strengthening industrial guidance and market management,etc.,which will benefit the rational utilization of tropical biological resources and increase the whole competitive advantage of decorative fishery in Hainan Province.

  5. Suggested drilling research tasks for the Federal Government

    Energy Technology Data Exchange (ETDEWEB)

    Carson, C.C.

    1984-04-01

    A brief summary discussion of drilling, drilling research and the role of the government in drilling research is presented. Specific research and development areas recommended for federal consideration are listed. The technical nature of the identified tasks is emphasized. The Appendices present the factual basis for the discussion and recommendations. Numerous references are noted in the Appendices.

  6. Quantitative Approaches to Group Research: Suggestions for Best Practices

    Science.gov (United States)

    McCarthy, Christopher J.; Whittaker, Tiffany A.; Boyle, Lauren H.; Eyal, Maytal

    2017-01-01

    Rigorous scholarship is essential to the continued growth of group work, yet the unique nature of this counseling specialty poses challenges for quantitative researchers. The purpose of this proposal is to overview unique challenges to quantitative research with groups in the counseling field, including difficulty in obtaining large sample sizes…

  7. Quantitative Approaches to Group Research: Suggestions for Best Practices

    Science.gov (United States)

    McCarthy, Christopher J.; Whittaker, Tiffany A.; Boyle, Lauren H.; Eyal, Maytal

    2017-01-01

    Rigorous scholarship is essential to the continued growth of group work, yet the unique nature of this counseling specialty poses challenges for quantitative researchers. The purpose of this proposal is to overview unique challenges to quantitative research with groups in the counseling field, including difficulty in obtaining large sample sizes…

  8. Psychotherapy training: Suggestions for core ingredients and future research.

    Science.gov (United States)

    Boswell, James F; Castonguay, Louis G

    2007-12-01

    Despite our considerable depth and breadth of empirical knowledge on psychotherapy process and outcome, research on psychotherapy training is somewhat lacking. We would argue, however, that the scientist-practitioner model should not only guide practice, but also the way our field approaches training. In this paper we outline our perspective on the crucial elements of psychotherapy training based on available evidence, theory, and clinical experience, focusing specifically on the structure, key components, and important skills to be learned in a successful training program. In addition, we derive specific research directions based on the crucial elements of our proposed training perspective, and offer general considerations for research on training, including method and measurement issues. (PsycINFO Database Record (c) 2010 APA, all rights reserved).

  9. Curriculum Alignment Research Suggests that Alignment Can Improve Student Achievement

    Science.gov (United States)

    Squires, David

    2012-01-01

    Curriculum alignment research has developed showing the relationship among three alignment categories: the taught curriculum, the tested curriculum and the written curriculum. Each pair (for example, the taught and the written curriculum) shows a positive impact for aligning those results. Following this, alignment results from the Third…

  10. What Brain Research Suggests for Teaching Reading Strategies

    Science.gov (United States)

    Willis, Judy

    2009-01-01

    How the brain learns to read has been the subject of much neuroscience educational research. Evidence is mounting for identifiable networks of connected neurons that are particularly active during reading processes such as response to visual and auditory stimuli, relating new information to prior knowledge, long-term memory storage, comprehension,…

  11. Curriculum Alignment Research Suggests that Alignment Can Improve Student Achievement

    Science.gov (United States)

    Squires, David

    2012-01-01

    Curriculum alignment research has developed showing the relationship among three alignment categories: the taught curriculum, the tested curriculum and the written curriculum. Each pair (for example, the taught and the written curriculum) shows a positive impact for aligning those results. Following this, alignment results from the Third…

  12. P Systems and Topology: Some Suggestions for Research

    OpenAIRE

    2009-01-01

    Lately, some studies linked the computational power of abstract computing systems based on multiset rewriting to Petri nets and the computation power of these nets to their topology. In turn, the computational power of these abstract computing devices can be understood just looking at their topology, that is, information flow. This line of research is very promising for several aspects: its results are valid for a broad range of systems based on multiset rewriting; it allows...

  13. Current Research in Southeast Asia.

    Science.gov (United States)

    Beh, Yolanda

    1988-01-01

    Briefly describes 22 reports on language-related research relevant to Southeast Asia, detailing study aims, methodology, researchers, and sponsors for studies conducted in Brunei Darussalam, Indonesia, Malaysia, Philippines, Singapore, and Thailand. (CB)

  14. Cell Phones: Current Research Results

    Science.gov (United States)

    ... Potential Biological or Adverse Health Effects of Wireless Communication Devices World Health Organization: Electromagnetic Fields and Public Health: Mobile Phones International Agency for Research on Cancer Press ...

  15. Plagiarism in Student Research: Responsibility of the Supervisors and Suggestions to Ensure Plagiarism Free Research.

    Science.gov (United States)

    Krishan, Kewal; Kanchan, Tanuj; Baryah, Neha; Mukhra, Richa

    2016-11-28

    Plagiarism is a serious threat plaguing the research in publication of science globally. There is an increasing need to address the issue of plagiarism especially among young researchers in the developing part of the world. Plagiarism needs to be earnestly discouraged to ensure a plagiarism free research environment. We provide further suggestions to combat student plagiarism at Master's level and the regulations/guidelines regarding plagiarism in India.

  16. Current concepts in cancer research

    Directory of Open Access Journals (Sweden)

    Ivan Kok Seng Yap

    2013-04-01

    Full Text Available Cancer research is an extremely broadtopic covering many scientific disciplines includingbiology (e.g. biochemistry and signal transduction,chemistry (e.g. drug discover and development,physics (e.g. diagnostic devices and even computerscience (e.g. bioinformatics. Some would argue thatcancer research will continue in much the same wayas it is by adding further layers of complexity to thescientific knowledge that is already complex and almostbeyond measure. But we anticipate that cancer researchwill undergo a dramatic paradigm shift due to therecent explosion of new discoveries in cancer biology.This review article focuses on the latest horizons incancer research concerning cancer epigenetics, cancerstem cells, cancer immunology and cancer metabolism.

  17. Current Research in Southeast Asia.

    Science.gov (United States)

    Beh, Yolanda

    1989-01-01

    Summaries of six language-related research projects are presented from Malaysia, Singapore, and Thailand. Topics include English as the instructional medium, teacher's use of language, Tamil language management, standardizing texts, cross-cultural business negotiations, and assessment of English language needs in computer science. (LB)

  18. Current Research Status of Allelopathy

    Directory of Open Access Journals (Sweden)

    AHMAD JUNAEDI

    2006-06-01

    Full Text Available The term of allelopathy refers to chemical interactions (inhibitory or stimulatory between plants, between plants and microorganisms, and between microorganisms. The wealth of information on the processes, procedures, and practices of allelopathy has contributed to understanding this field of science. Recently, researches of allelopathy have been conducted in laboratory, greenhouse, and field with multifaceted standpoint in some concerning area: (i allelochemicals identifications and screening test; (ii ecological and physiological aspects of allelopathy; (iii genetic studies and the possibilities of using plant breeding or genetic manipulation to enhance allelopathic varieties; (iv the use of allelopathic potential in the biological control, including as natural pesticide, of weeds and plant diseases as eco-friendly approach for sustainable agriculture scheme.

  19. Culture Teaching in China’s Current College English Class and Some Suggestions

    Institute of Scientific and Technical Information of China (English)

    李思远

    2014-01-01

    Culture is an important part in foreign language learning because no language can leave its culture contexts. Therefore, if one wants to learn a foreign language well, the acculturation is very important. But in the Chinese EFL classroom, for kinds of reasons, teachers often pay more attention to the explanation of grammatical rules and ignored the culture input which makes many Chinese students lack of pragmatic competence and can not use English in a proper way. This article will analyze the cur-rent culture teaching in our college English class and propose some suggestions.

  20. Current Research on Antiepileptic Compounds

    Directory of Open Access Journals (Sweden)

    Cheng-Xi Wei

    2015-11-01

    Full Text Available Epilepsy affects about 1% of the world’s population. Due to the fact all antiepileptic drugs (AEDs have some undesirable side effects and about 30% of epileptic patients are not seizure-free with the existing AEDs, there is still an urgent need for the development of more effective and safer AEDs. Based on our research work on antiepileptic compounds and other references in recent years, this review covers the reported work on antiepileptic compounds which are classified according to their structures. This review summarized 244 significant anticonvulsant compounds which are classified by functional groups according to the animal model data, although there are some limitations in the data. This review highlights the properties of new compounds endowed with promising antiepileptic properties, which may be proven to be more effective and selective, and possibly free of unwanted side effects. The reviewed compounds represent an interesting possibility to overcome refractory seizures and to reduce the percentage of patients with a poor response to drug therapy.

  1. Current demographics suggest future energy supplies will be inadequate to slow human population growth.

    Directory of Open Access Journals (Sweden)

    John P DeLong

    Full Text Available Influential demographic projections suggest that the global human population will stabilize at about 9-10 billion people by mid-century. These projections rest on two fundamental assumptions. The first is that the energy needed to fuel development and the associated decline in fertility will keep pace with energy demand far into the future. The second is that the demographic transition is irreversible such that once countries start down the path to lower fertility they cannot reverse to higher fertility. Both of these assumptions are problematic and may have an effect on population projections. Here we examine these assumptions explicitly. Specifically, given the theoretical and empirical relation between energy-use and population growth rates, we ask how the availability of energy is likely to affect population growth through 2050. Using a cross-country data set, we show that human population growth rates are negatively related to per-capita energy consumption, with zero growth occurring at ∼13 kW, suggesting that the global human population will stop growing only if individuals have access to this amount of power. Further, we find that current projected future energy supply rates are far below the supply needed to fuel a global demographic transition to zero growth, suggesting that the predicted leveling-off of the global population by mid-century is unlikely to occur, in the absence of a transition to an alternative energy source. Direct consideration of the energetic constraints underlying the demographic transition results in a qualitatively different population projection than produced when the energetic constraints are ignored. We suggest that energetic constraints be incorporated into future population projections.

  2. Every scientist is a memory researcher: Suggestions for making research more memorable.

    Science.gov (United States)

    Madan, Christopher R

    2015-01-01

    Independent of the actual results, some scientific articles are more memorable than others. As anyone who has written an article collaboratively knows, there are numerous ways a manuscript can be written to convey the same general ideas. To aid with this, many scientific writing books and editorials provide advice, often anecdotal, on how to make articles more memorable. Here I ground these suggestions with empirical support from memory research. Specifically, I suggest that researchers consider how to emphasize their work's novelty, strive to describe their work using concrete, easy-to-understand terms, and use caution when attempting to evoke an emotional response in the reader. I also discuss considerations in title selections and conference presentations.

  3. Affordances of Augmented Reality in Science Learning: Suggestions for Future Research

    Science.gov (United States)

    Cheng, Kun-Hung; Tsai, Chin-Chung

    2013-08-01

    Augmented reality (AR) is currently considered as having potential for pedagogical applications. However, in science education, research regarding AR-aided learning is in its infancy. To understand how AR could help science learning, this review paper firstly has identified two major approaches of utilizing AR technology in science education, which are named as image- based AR and location- based AR. These approaches may result in different affordances for science learning. It is then found that students' spatial ability, practical skills, and conceptual understanding are often afforded by image-based AR and location-based AR usually supports inquiry-based scientific activities. After examining what has been done in science learning with AR supports, several suggestions for future research are proposed. For example, more research is required to explore learning experience (e.g., motivation or cognitive load) and learner characteristics (e.g., spatial ability or perceived presence) involved in AR. Mixed methods of investigating learning process (e.g., a content analysis and a sequential analysis) and in-depth examination of user experience beyond usability (e.g., affective variables of esthetic pleasure or emotional fulfillment) should be considered. Combining image-based and location-based AR technology may bring new possibility for supporting science learning. Theories including mental models, spatial cognition, situated cognition, and social constructivist learning are suggested for the profitable uses of future AR research in science education.

  4. Bioremediation via Methanotrophy: Overview of Recent Findings and Suggestions for Future Research

    Directory of Open Access Journals (Sweden)

    Jeremy eSemrau

    2011-10-01

    Full Text Available Microbially-mediated bioremediation of polluted sites has been a subject of much research over the past 30 years, with many different compounds shown to be degraded under both aerobic and anaerobic conditions. Aerobic-mediated bioremediation commonly examines the use of methanotrophs, microorganisms that consume methane as their sole source of carbon and energy. Given the diverse environments in which methanotrophs have been found, the range of substrates they can degrade and the fact that they can be easily stimulated with the provision of methane and oxygen, these microorganisms in particular have been examined for aerobic degradation of chlorinated hydrocarbons. The physiological and phylogenetic diversity of methanotrophy, however, has increased substantially in just the past five years. Here in this review, the current state of knowledge of methanotrophy, particularly as it applies to pollutant degradation is summarized, and suggestions for future research provided.

  5. Current challenges in dedifferentiated fat cells research.

    Science.gov (United States)

    Shah, Mickey; George, Richard L; Evancho-Chapman, M Michelle; Zhang, Ge

    2016-07-02

    Dedifferentiated fat cells show great promises as a novel cell source for stem cell research. It has many advantages when used for cell-based therapeutics including abundance, pluripotency, and safety. However, there are many obstacles researchers need to overcome to make the next big move in DFAT cells research. In this review, we summarize the current main challenges in DFAT cells research including cell culture purity, phenotypic properties, and dedifferentiation mechanisms. The common methods to produce DFAT cells as well as the cell purity issue during DFAT cell production have been introduced. Current approaches to improve DFAT cell purity have been discussed. The phenotypic profile of DFAT cells have been listed and compared with other stem cells. Further studies on elucidating the underlying dedifferentiation mechanisms will dramatically advance DFAT cell research.

  6. Current status and future research in motion planning

    Energy Technology Data Exchange (ETDEWEB)

    Hwang, Y.K.

    1995-07-01

    There have been numerous research efforts in the field of motion planning, resulting in many theoretical and practical results. We review the current status of existing motion planning algorithms, evaluate their completeness and efficiencies on modern computers, and suggest fruitful future research directions.

  7. Current research on aviation weather (bibliography), 1979

    Science.gov (United States)

    Turkel, B. S.; Frost, W.

    1980-01-01

    The titles, managers, supporting organizations, performing organizations, investigators and objectives of 127 current research projects in advanced meteorological instruments, forecasting, icing, lightning, visibility, low level wind shear, storm hazards/severe storms, and turbulence are tabulated and cross-referenced. A list of pertinent reference material produced through the above tabulated research activities is given. The acquired information is assembled in bibliography form to provide a readily available source of information in the area of aviation meteorology.

  8. Spectroscopic observations of evolving flare ribbon substructure suggesting origin in current sheet waves

    Science.gov (United States)

    Brannon, Sean R.; Longcope, Dana; Qiu, Jiong

    2015-04-01

    A flare ribbon is the chromospheric image of reconnection at a coronal current sheet. The dynamics and structure of the ribbon can thus reveal properties of the current sheet, including motion of the reconnecting flare loops. We present imaging and spectroscopic observations from the Interface Region Imaging Spectrograph (IRIS) of the evolution of a flare ribbon at high spatial resolution and time cadence. These reveal small-scale substructure in the ribbon, which manifest as oscillations in both position and Doppler velocities. We consider various alternative explanations for these oscillations, including modulation of chromospheric evaporation flows. Among these we find the best support for some form of elliptical wave localized to the coronal current sheet, such as a tearing mode or Kelvin-Helmholtz instability.IRIS is a NASA Small Explorer mission developed and operated by Lockheed Martin Solar and Astrophysics Laboratory. This work is supported by contract 8100002702 from Lockheed Martin to Montana State University, a Montana Space Grant Consortium fellowship, and by NASA through HSR.

  9. Digital library research : current developments and trends

    OpenAIRE

    Shiri, Ali

    2003-01-01

    This column gives an overview of current trends in digital library research under the following headings: digital library architecture, systems, tools and technologies; digital content and collections; metadata; interoperability; standards; knowledge organisation systems; users and usability; legal, organisational, economic, and social issues in digital libraries.

  10. Hepatitis B Vaccination in Bangladesh: a Suggestion Based on Current Evidence

    Directory of Open Access Journals (Sweden)

    Shafquat Mohammed Rafiq

    2006-12-01

    . Relying on these statistics Bangladesh can be categorized as an intermediate endemic zone for HBV(12. Unfortunately, despite an increased prevalence of HBV infection, the country has not incorporated hepatitis B vaccination into its national childhood immunization policy until recently, most probably because of its economic constraints. Presently it offers three doses hepatitis B vaccine to all babies. It is felt that the current regimen was drawn in on the basis of ongoing uncertainties and disagreements surrounding the vaccine all over the globe.Uncertainties Surrounding HBV ImmunizationThe rationale of HBV immunization is illustrated in the box; however uncertainties surrounding HBV immunization do exist, these are:Box: Rationale of Hepatitis B Immunization The rationale of HBV vaccination is to prevent: · Episodes of acute hepatitis B · Chronic hepatitis B surface antigenaemia · Chronic hepatitis and the need for therapy · Hepatocellular carcinoma · HBV transmission Correspondence:Dr. Harunor Rashid, Research Fellow, Academic Departmentof Child Health, Queen Mary University of London, 38 NewRoad, London, E1 2AX, UKFax: +44(02073777167E-mail: h.rashid@qmul.ac.ukHep Mon 2006; 6 (1: 41-44 - Duration of vaccine- induced immunity:It has been shown that immunization with three doses of HBV vaccine provides acceptable level of seroprotection for at least five years(13. Titersdecreased to 99% of the 14 year olds had titers of |“|10mIU/mL while one year after the booster 10mIU/mL after 1 month of first, second and third vaccinations were 58%, 70% and 94% respectively(16. However, it has been observed in other studies that two doses of recombinant HBV vaccine given over 4 or 6 months provide adequate seroprotection (|“|10mIU/mL in |“|95% of adolescent vaccines(13,17. There were small variations in vaccine response between infants and teenagers. The range of protection for different doses is shown in Table(17. If we accept that a level of 80-95% seroprotection is

  11. A Suggested Research Agenda on Treatment-Outcome Research for Female Victims of Violence

    Science.gov (United States)

    Resick, Patricia A.

    2004-01-01

    I appreciate the opportunity to present my opinions on the appropriate course for the research agenda on violence against women. Briere and Jordan (this issue) have done an estimable job in reviewing the research on the psychological impact of violence on women and have concluded that, because psychological symptoms following victimization are…

  12. Neuroimaging for psychotherapy research: current trends.

    Science.gov (United States)

    Weingarten, Carol P; Strauman, Timothy J

    2015-01-01

    This article reviews neuroimaging studies that inform psychotherapy research. An introduction to neuroimaging methods is provided as background for the increasingly sophisticated breadth of methods and findings appearing in psychotherapy research. We compiled and assessed a comprehensive list of neuroimaging studies of psychotherapy outcome, along with selected examples of other types of studies that also are relevant to psychotherapy research. We emphasized magnetic resonance imaging (MRI) since it is the dominant neuroimaging modality in psychological research. We summarize findings from neuroimaging studies of psychotherapy outcome, including treatment for depression, obsessive compulsive disorder (OCD), and schizophrenia. The increasing use of neuroimaging methods in the study of psychotherapy continues to refine our understanding of both outcome and process. We suggest possible directions for future neuroimaging studies in psychotherapy research.

  13. Welfare assessment in porcine biomedical researchSuggestion for an operational tool

    DEFF Research Database (Denmark)

    Søndergaard, Lene Vammen; Dagnæs-Hansen, Frederik; Herskin, Mette S

    2011-01-01

    In recent years, increasing interest in using the pig (Sus scrofa) for biomedical research has become evident. Today, the pig is considered an advantageous alternative animal model for various human diseases and conditions. However, even though a considerable amount of biomedical research has been...... of the extent of welfare assessment in pigs used in biomedical research and to suggest a welfare assessment standard for research facilities based on an exposition of ethological considerations relevant for the welfare of pigs in biomedical research. The tools for porcine welfare assessment presented suggest...

  14. The rings of Saturn: State of current knowledge and some suggestions for future studies

    Science.gov (United States)

    Cuzzi, J. N.

    1978-01-01

    The state of our current knowledge of the properties of the ring system as a whole, and of the particles individually, is assessed. Attention is primarily devoted to recent results and possibilities for exploration of the ring system by a Saturn orbiter. In particular, the infrared and microwave properties of the ring system are discussed. The behavior of the ring brightness is not well understood in the critical transition spectral region from approximately 100 micrometers to approximately 1 cm. Also, the dynamical behavior of the ring system is discussed. Recent theoretical studies show that ongoing dynamical effects continually affect the ring structure in azimuth (possibly producing the A ring brightness asymmetry) and in the vertical direction. Orbital spacecraft-based studies of the rings will offer several unique advantages and impact important cosmogonical questions. Bistatic radar studies and millimeter-wavelength spectrometer/radiometry will give particle sizes and composition limits needed to resolve the question of the density of the rings, and provide important boundary conditions on the state of Saturn's protoplanetary nebula near the time of planetary formation.

  15. Current research of hepatic cirrhosis in China

    Institute of Scientific and Technical Information of China (English)

    Xi-Xian Yao; Shu-Lin Jiang; Dong-Mei Yao

    2005-01-01

    Hepatic cirrhosis is a common disease that poses a serious threat to public health, and is characterized by chronic,progressive and diffuse hepatic lesions preceded by hepaticfibrosis regardless of the exact etiologies. In recent years,considerable achievements have been made in China in research of the etiopathogenesis, diagnosis and especially the treatment of hepatic fibrosis, resulting in much improved prognosis of hepatic fibrosis and cirrhosis. In this paper, the authors review the current status of research in hepatic fibrosis, cirrhosis and their major complications.

  16. Mechanisms and Kinetics of Environmentally Assisted Cracking: Current Status, Issues, and Suggestions for Further Work

    Science.gov (United States)

    Lynch, S. P.

    2013-03-01

    Mechanisms and kinetics of metal-induced embrittlement, hydrogen-embrittlement, and stress-corrosion cracking are discussed, and long-standing controversies are addressed by reviewing critical observations. Recommendations are also made regarding further work (including repetition of previous work using more advanced measurement and characterisation techniques) that should be carried out in order to resolve some of the contentious issues. The evidence to date suggests that adsorption-based mechanisms, involving weakening of substrate interatomic bonds so that dislocation emission or decohesion is facilitated, accounts for embrittlement in many systems. Embrittling adsorbed species include some metal atoms, hydrogen, and complex ions produced by de-alloying. Other viable mechanisms of embrittlement include those based on (1) dissolution of anodic grain-boundary regions, and (2) decohesion at grain boundaries owing to segregated hydrogen and impurities. The hydrogen-enhanced localised-plasticity mechanism, based on solute hydrogen facilitating dislocation activity in the plastic zone ahead of cracks, makes a contribution in some cases, but is relatively unimportant compared with these other mechanisms for most fracture modes. The film-induced cleavage mechanism, proposed especially for stress-corrosion cracking in systems involving de-alloying at crack tips, is questionable on numerous grounds, and is probably not viable. Rate-controlling processes for environmentally assisted cracking are not well established, except for solid-metal induced embrittlement where surface self-diffusion of embrittling atoms to crack tips controls cracking kinetics. In some systems, adsorption kinetics are probably rate-controlling for liquid-metal embrittlement, hydrogen-environment embrittlement, and stress-corrosion cracking. In other cases, rate-controlling processes could include the rate of anodic or cathodic reactions at and behind crack tips (responsible for producing embrittling

  17. Medical Robots: Current Systems and Research Directions

    OpenAIRE

    Beasley, Ryan A.

    2012-01-01

    First used medically in 1985, robots now make an impact in laparoscopy, neurosurgery, orthopedic surgery, emergency response, and various other medical disciplines. This paper provides a review of medical robot history and surveys the capabilities of current medical robot systems, primarily focusing on commercially available systems while covering a few prominent research projects. By examining robotic systems across time and disciplines, trends are discernible that imply future capabilities ...

  18. Informal Mentoring at Work: A Review and Suggestions for Future Research

    NARCIS (Netherlands)

    Janssen, Suzanne; Vuuren, van Mark; Jong, de Menno D.T.

    2016-01-01

    This paper reviews the literature on informal mentoring at work. Based on two basic premises of interpersonal relationships, it discusses four promising areas in current mentoring research that could be cultivated further by future research. The first premise that we hold is that relationships never

  19. Informal mentoring at work: A review and suggestions for future research

    NARCIS (Netherlands)

    Janssen, Suzanne; van Vuuren, Hubrecht A.; de Jong, Menno D.T.

    2016-01-01

    This paper reviews the literature on informal mentoring at work. Based on two basic premises of interpersonal relationships, it discusses four promising areas in current mentoring research that could be cultivated further by future research. The first premise that we hold is that relationships never

  20. 16 CFR Figures 1 and 2 to Part 1204 - Suggested Instrumentation for Current Monitoring Device and High Voltage Facility

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Suggested Instrumentation for Current Monitoring Device and High Voltage Facility 1 Figures 1 and 2 to Part 1204 Commercial Practices CONSUMER... Instrumentation for Current Monitoring Device and High Voltage Facility EC03OC91.008...

  1. Integrated fundamental research on current collection

    Science.gov (United States)

    Kuhlmann-Wilsdorf, Doris; Tran, Leo

    1993-06-01

    The aim of our research was to add to the basic understanding in the area of current collection with particular emphasis on topics likely to benefit practical objectives. Under sponsorship of this contract, 23 papers were published in the international literature. Additionally, 13 invited lectures and 11 contributed lectures on various aspects of this research were delivered at universities, research laboratories, and international conferences by the principal investigator and co-workers. The development of a novel metal fiber material for sliding electrical contacts was continued with much success. This is expected to become very useful for making metal fiber brushed for homopolar motors/generators, as well as for EML armatures. Included in this report are title pages (and abstracts) for the 23 published papers.

  2. CURRENT STATE OF HISTORIC AND EDUCATIONAL RESEARCH

    Directory of Open Access Journals (Sweden)

    Magsumov Timur Albertovich

    2013-05-01

    Full Text Available In this paper we analyze the results of development of national historic and educational research at the turn of the XXth century; pinpoint obvious success and indicate problems and contradictory areas; give grounding to the development model of the XXth century Russian pedagogy; make suggestions on the strategy and tactics of further development of historic and educational science and suggest areas for further research. They are ‘new social history’ of education, professional education and teacher training, personified microhistory and history of local educational environment, genesis of didactic principles, ethno-pedagogy, country school, pedagogical diagnostics, Orthodox religious education, contemporary history of foreign pedagogy, pedagogical futurology. We prove the need in reassessment of certain studies’ viability. We draw the conclusion that historic and educational knowledge determines areas and instruments to understand the problems of educational issues, their roots and realize the existence of ways to solve them.

  3. Regulations and Ethical Considerations for Astronomy Education Research III: A Suggested Code of Ethics

    Science.gov (United States)

    Brogt, Erik; Foster, Tom; Dokter, Erin; Buxner, Sanlyn; Antonellis, Jessie

    2009-01-01

    We present an argument for, and suggested implementation of, a code of ethics for the astronomy education research community. This code of ethics is based on legal and ethical considerations set forth by U.S. federal regulations and the existing code of conduct of the American Educational Research Association. We also provide a fictitious research…

  4. Medical Robots: Current Systems and Research Directions

    Directory of Open Access Journals (Sweden)

    Ryan A. Beasley

    2012-01-01

    Full Text Available First used medically in 1985, robots now make an impact in laparoscopy, neurosurgery, orthopedic surgery, emergency response, and various other medical disciplines. This paper provides a review of medical robot history and surveys the capabilities of current medical robot systems, primarily focusing on commercially available systems while covering a few prominent research projects. By examining robotic systems across time and disciplines, trends are discernible that imply future capabilities of medical robots, for example, increased usage of intraoperative images, improved robot arm design, and haptic feedback to guide the surgeon.

  5. Topics in current aerosol research (part2)

    CERN Document Server

    Hidy, G M

    1972-01-01

    Topics in Current Aerosol Research, Part 2 contains some selected articles in the field of aerosol study. The chosen topics deal extensively with the theory of diffusiophoresis and thermophoresis. Also covered in the book is the mathematical treatment of integrodifferential equations originating from the theory of aerosol coagulation. The book is the third volume of the series entitled International Reviews in Aerosol Physics and Chemistry. The text offers significant understanding of the methods employed to develop a theory for thermophoretic and diffusiophoretic forces acting on spheres in t

  6. Affordances of Augmented Reality in Science Learning: Suggestions for Future Research

    Science.gov (United States)

    Cheng, Kun-Hung; Tsai, Chin-Chung

    2013-01-01

    Augmented reality (AR) is currently considered as having potential for pedagogical applications. However, in science education, research regarding AR-aided learning is in its infancy. To understand how AR could help science learning, this review paper firstly has identified two major approaches of utilizing AR technology in science education,…

  7. Leadership: current theories, research, and future directions.

    Science.gov (United States)

    Avolio, Bruce J; Walumbwa, Fred O; Weber, Todd J

    2009-01-01

    This review examines recent theoretical and empirical developments in the leadership literature, beginning with topics that are currently receiving attention in terms of research, theory, and practice. We begin by examining authentic leadership and its development, followed by work that takes a cognitive science approach. We then examine new-genre leadership theories, complexity leadership, and leadership that is shared, collective, or distributed. We examine the role of relationships through our review of leader member exchange and the emerging work on followership. Finally, we examine work that has been done on substitutes for leadership, servant leadership, spirituality and leadership, cross-cultural leadership, and e-leadership. This structure has the benefit of creating a future focus as well as providing an interesting way to examine the development of the field. Each section ends with an identification of issues to be addressed in the future, in addition to the overall integration of the literature we provide at the end of the article.

  8. Research Reproducibility in Geosciences: Current Landscape, Practices and Perspectives

    Science.gov (United States)

    Yan, An

    2016-04-01

    Reproducibility of research can gauge the validity of its findings. Yet currently we lack understanding of how much of a problem research reproducibility is in geosciences. We developed an online survey on faculty and graduate students in geosciences, and received 136 responses from research institutions and universities in Americas, Asia, Europe and other parts of the world. This survey examined (1) the current state of research reproducibility in geosciences by asking researchers' experiences with unsuccessful replication work, and what obstacles that lead to their replication failures; (2) the current reproducibility practices in community by asking what efforts researchers made to try to reproduce other's work and make their own work reproducible, and what the underlying factors that contribute to irreproducibility are; (3) the perspectives on reproducibility by collecting researcher's thoughts and opinions on this issue. The survey result indicated that nearly 80% of respondents who had ever reproduced a published study had failed at least one time in reproducing. Only one third of the respondents received helpful feedbacks when they contacted the authors of a published study for data, code, or other information. The primary factors that lead to unsuccessful replication attempts are insufficient details of instructions in published literature, and inaccessibility of data, code and tools needed in the study. Our findings suggest a remarkable lack of research reproducibility in geoscience. Changing the incentive mechanism in academia, as well as developing policies and tools that facilitate open data and code sharing are the promising ways for geosciences community to alleviate this reproducibility problem.

  9. Current and Future Research at DANCE

    Directory of Open Access Journals (Sweden)

    Jandel M.

    2015-01-01

    Full Text Available An overview of the current experimental program on measurements of neutron capture and neutron induced fission at the Detector for Advanced Neutron Capture Experiments (DANCE is presented. Three major projects are currently under way: 1 high precision measurements of neutron capture cross sections on Uranium isotopes, 2 research aimed at studies of the short-lived actinide isomer production in neutron capture on 235U and 3 measurements of correlated data of fission observables. New projects include developments of auxiliary detectors to improve the capability of DANCE. We are building a compact, segmented NEUtron detector Array at DANCE (NEUANCE, which will be installed in the central cavity of the DANCE array. It will provide experimental information on prompt fission neutrons in coincidence with the prompt fission gamma-rays measured by 160 BaF2 crystals of DANCE. Unique correlated data will be obtained for neutron capture and neutron-induced fission using the DANCE-NEUANCE experimental set up in the future.

  10. Current and Future Research at DANCE

    Science.gov (United States)

    Jandel, M.; Baramsai, B.; Bredeweg, T. A.; Couture, A.; Hayes, A.; Kawano, T.; Mosby, S.; Rusev, G.; Stetcu, I.; Taddeucci, T. N.; Talou, P.; Ullmann, J. L.; Walker, C. L.; Wilhelmy, J. B.

    2015-05-01

    An overview of the current experimental program on measurements of neutron capture and neutron induced fission at the Detector for Advanced Neutron Capture Experiments (DANCE) is presented. Three major projects are currently under way: 1) high precision measurements of neutron capture cross sections on Uranium isotopes, 2) research aimed at studies of the short-lived actinide isomer production in neutron capture on 235U and 3) measurements of correlated data of fission observables. New projects include developments of auxiliary detectors to improve the capability of DANCE. We are building a compact, segmented NEUtron detector Array at DANCE (NEUANCE), which will be installed in the central cavity of the DANCE array. It will provide experimental information on prompt fission neutrons in coincidence with the prompt fission gamma-rays measured by 160 BaF2 crystals of DANCE. Unique correlated data will be obtained for neutron capture and neutron-induced fission using the DANCE-NEUANCE experimental set up in the future.

  11. Public Opinion Research as a Basis for Student Learning: A Suggested Teaching Model.

    Science.gov (United States)

    Nickerson, Brian J.

    This paper provides a suggested teaching model enabling students to conduct extensive, hands-on survey research as the basis of part or all of a political science class. The model emphasizes active student learning and development of applied skills. The components of this model can be modified for use in a broad array of undergraduate political…

  12. Agriculture for improved nutrition: the current research landscape.

    Science.gov (United States)

    Turner, Rachel; Hawkes, Corinna; Jeff, Waage; Ferguson, Elaine; Haseen, Farhana; Homans, Hilary; Hussein, Julia; Johnston, Deborah; Marais, Debbi; McNeill, Geraldine; Shankar, Bhavani

    2013-12-01

    Concern about food security and its effect on persistent undernutrition has increased interest in how agriculture could be used to improve nutritional outcomes in developing countries. Yet the evidence base for the impact of agricultural interventions targeted at improved nutrition is currently poor. To map the extent and nature of current and planned research on agriculture for improved nutrition in order to identify gaps where more research might be useful. The research, which was conducted from April to August 2012, involved developing a conceptual framework linking agriculture and nutrition, identifying relevant research projects and programs, devising and populating a "template" with details of the research projects in relation to the conceptual framework, classifying the projects, and conducting a gap analysis. The study identified a large number of research projects covering a broad range of themes and topics. There was a strong geographic focus on sub-Saharan Africa, and many studies were explicitly concerned with nutritional impacts on women and children. Although the study revealed a diverse and growing body of research, it also identified research gaps. Few projects consider the entire evidence chain linking agricultural input or practice to nutritional outcomes. There is comparatively little current research on indirect effects of agriculture on nutrition, or the effect of policies or governance, rather than technical interventions. Most research is focused on undernutrition and small farmer households, and few studies target consumers generally, urban populations, or nutrition-related non-communicable diseases. There is very little work on the cost-effectiveness of agricultural interventions. On the basis of these findings, we make suggestions for research investment and for broader engagement of researchers and disciplines in developing approaches to design and evaluate agricultural programs for improved nutrition.

  13. Current research directions definition of economic security

    Directory of Open Access Journals (Sweden)

    Anna Falovych

    2013-05-01

    Full Text Available The article features the topical issue of the established level of the enterprise's economic security. The objective of this article is to research, to base and to supplement the tendency for generalization of the categorical system in order to clarify the matter meaning of the enterprise's economic security. The systematized analyses of the matter meaning of the enterprise's economic security were done by domestic and foreign scientists-economists. The results of the study were expounded and also some vital approaches to the definition of the enterprise's economic security were presented and proved particularly: strategically, resource-functional, marketable, combined, deductive, systematic and criminal.Based on the analyzed content-conceptual interpretations and detailed characteristics of each approach to the definition of this meaning, there was proposed its own meaning of the interpretation of the enterprise's economic security. A systematic approach was adopted due to the matters concerning enterprise's economic security. As in this approach the vital economic interests of thee enterprise were stipulated, also gained the topicality in the current crisis economic conditions

  14. CURRENT ANSTO RESEARCH ON WASTEFORM DEVELOPMENT

    Energy Technology Data Exchange (ETDEWEB)

    Vance, E.R.; Perera, D.S.; Stewart, M.W.A.; Begg, B.D.; Carter, M.L.; Day, R.A.; Moricca, S.; Smith, K.L.; Lumpkin, G.R.; Hanna, J.V.

    2003-02-27

    Current ANSTO scientific research on wasteform development for mainly high-level radioactive waste is directed towards practical applications. Titanate wasteform products we have developed or are developing are aimed at immobilization of: (a) tank wastes and sludges; (b) U-rich wastes from radioisotope production from reactor irradiation of UO2 targets; (c) Al-rich wastes arising from reprocessing of Al-clad fuels; (d) 99Tc; (e) high- Mo wastes arising from reprocessing of U-Mo fuels and (f) partitioned Cs-rich wastes. Other wasteforms include encapsulated zeolites or silica/alumina beads for immobilization of 129I. Wasteform production techniques cover hot isostatic and uniaxial pressing, sintering, and cold-crucible melting. In addition, building on previous work on speciation and leach resistance of Cs in cementitious products, we are studying geopolymers. Although we have a strong focus on candidate wasteforms for actual wastes, we have a considerable program directed at basic understanding of the wasteforms in regard to crystal chemistry, their dissolution behavior in aqueous media, radiation damage effects and processing techniques.

  15. Current Research on Effective Classroom Management.

    Science.gov (United States)

    Emmer, Edmund T.

    This presentation provides an overview of research on classroom management, emphasizing results from a program of research conducted at the Research and Development Center for Teacher Education (University of Texas) during the last 5 years. These studies, along with others, provide a basis for describing important dimensions of teacher behavior…

  16. Current trends in free software research

    OpenAIRE

    Navarro Bosch, Ramon; Vila Marta, Sebastià

    2009-01-01

    This report analyzes how scientific research is studying free software. We find which research is being done on free software by looking into scientific journals and conferences publications. The data thus obtained is analized and the most salient trends related to free software discovered. We also reviewed the main works published in each free software research area.

  17. Statistics used in current nursing research.

    Science.gov (United States)

    Zellner, Kathleen; Boerst, Connie J; Tabb, Wil

    2007-02-01

    Undergraduate nursing research courses should emphasize the statistics most commonly used in the nursing literature to strengthen students' and beginning researchers' understanding of them. To determine the most commonly used statistics, we reviewed all quantitative research articles published in 13 nursing journals in 2000. The findings supported Beitz's categorization of kinds of statistics. Ten primary statistics used in 80% of nursing research published in 2000 were identified. We recommend that the appropriate use of those top 10 statistics be emphasized in undergraduate nursing education and that the nursing profession continue to advocate for the use of methods (e.g., power analysis, odds ratio) that may contribute to the advancement of nursing research.

  18. Current status of nuclear physics research

    Energy Technology Data Exchange (ETDEWEB)

    Bertulani, Carlos A. [Department of Physics and Astronomy, Texas A and M University-Commerce (United States); Hussein, Mahir S., E-mail: hussein@if.usp.br [Instituto Tecnologico de Aeronautica (ITA), Sao Jose dos Campos, SP (Brazil). Dept. de Fisica

    2015-12-15

    In this review, we discuss the current status of research in nuclear physics which is being carried out in different centers in the world. For this purpose, we supply a short account of the development in the area which evolved over the last nine decades, since the discovery of the neutron. The evolution of the physics of the atomic nucleus went through many stages as more data became available. We briefly discuss models introduced to discern the physics behind the experimental discoveries, such as the shell model, the collective model, the statistical model, the interacting boson model, etc., some of these models may be seemingly in conflict with each other, but this was shown to be only apparent. The richness of the ideas and abundance of theoretical models attests to the important fact that the nucleus is a really singular system in the sense that it evolves from two-body bound states such as the deuteron, to few-body bound states, such as {sup 4}He, {sup 7}Li, {sup 9}Be, etc. and up the ladder to heavier bound nuclei containing up to more than 200 nucleons. Clearly, statistical mechanics, usually employed in systems with very large number of particles, would seemingly not work for such finite systems as the nuclei, neither do other theories which are applicable to condensed matter. The richness of nuclear physics stems from these restrictions. New theories and models are presently being developed. Theories of the structure and reactions of neutron-rich and proton-rich nuclei, called exotic nuclei, halo nuclei, or Borromean nuclei, deal with the wealth of experimental data that became available in the last 35 years. Furthermore, nuclear astrophysics and stellar and Big Bang nucleosynthesis have become a more mature subject. Due to limited space, this review only covers a few selected topics, mainly those with which the authors have worked on. Our aimed potential readers of this review are nuclear physicists and physicists in other areas, as well as graduate

  19. Current Status of Nuclear Physics Research

    Science.gov (United States)

    Bertulani, Carlos A.; Hussein, Mahir S.

    2015-12-01

    In this review, we discuss the current status of research in nuclear physics which is being carried out in different centers in the world. For this purpose, we supply a short account of the development in the area which evolved over the last nine decades, since the discovery of the neutron. The evolution of the physics of the atomic nucleus went through many stages as more data became available. We briefly discuss models introduced to discern the physics behind the experimental discoveries, such as the shell model, the collective model, the statistical model, the interacting boson model, etc., some of these models may be seemingly in conflict with each other, but this was shown to be only apparent. The richness of the ideas and abundance of theoretical models attests to the important fact that the nucleus is a really singular system in the sense that it evolves from two-body bound states such as the deuteron, to few-body bound states, such as 4He, 7Li, 9Be, etc. and up the ladder to heavier bound nuclei containing up to more than 200 nucleons. Clearly, statistical mechanics, usually employed in systems with very large number of particles, would seemingly not work for such finite systems as the nuclei, neither do other theories which are applicable to condensed matter. The richness of nuclear physics stems from these restrictions. New theories and models are presently being developed. Theories of the structure and reactions of neutron-rich and proton-rich nuclei, called exotic nuclei, halo nuclei, or Borromean nuclei, deal with the wealth of experimental data that became available in the last 35 years. Furthermore, nuclear astrophysics and stellar and Big Bang nucleosynthesis have become a more mature subject. Due to limited space, this review only covers a few selected topics, mainly those with which the authors have worked on. Our aimed potential readers of this review are nuclear physicists and physicists in other areas, as well as graduate students interested in

  20. Structural and acoustic response due to excitation from ship stern: overview and suggestions for future research

    Directory of Open Access Journals (Sweden)

    HUA Hongxing

    2017-08-01

    Full Text Available Several decades after the development of acoustic stealth technology for ships, there remains an urgent necessity to reduce low frequency structural and acoustic response due to excitation from the stern. This paper reviews research into the coupled vibration and acoustic problems of the sterns of vessels. Attention is especially paid to three key aspects: the characteristics of propeller forces, the vibration-acoustic signatures of coupled propeller-shaft-hull systems, and vibration/noise controls. Therefore, the mapping relationships of vibration noise from the stern excitation and propeller-shaft-hull system is obtained, and the control approaches for low frequency vibration noise is presented. Thereafter, several suggestions are made for further research work in the testing technology of the unsteady force of propellers, the structural vibration induced by the stern bearing friction and the vibration control of propeller-shaft systems in the future.

  1. Solid-State Lighting 2017 Suggested Research Topics Supplement: Technology and Market Context

    Energy Technology Data Exchange (ETDEWEB)

    None

    2017-09-29

    A 2017 update to the Solid-State Lighting R&D Plan that is divided into two documents. The first document describes a list of suggested SSL priority research topics and the second document provides context and background, including information drawn from technical, market, and economic studies. Widely referenced by industry and government both here and abroad, these documents reflect SSL stakeholder inputs on key R&D topics that will improve efficacy, reduce cost, remove barriers to adoption, and add value for LED and OLED lighting solutions over the next three to five years, and discuss those applications that drive and prioritize the specific R&D.

  2. Quantitative Risk reduction estimation Tool For Control Systems, Suggested Approach and Research Needs

    Energy Technology Data Exchange (ETDEWEB)

    Miles McQueen; Wayne Boyer; Mark Flynn; Sam Alessi

    2006-03-01

    For the past year we have applied a variety of risk assessment technologies to evaluate the risk to critical infrastructure from cyber attacks on control systems. More recently, we identified the need for a stand alone control system risk reduction estimation tool to provide owners and operators of control systems with a more useable, reliable, and credible method for managing the risks from cyber attack. Risk is defined as the probability of a successful attack times the value of the resulting loss, typically measured in lives and dollars. Qualitative and ad hoc techniques for measuring risk do not provide sufficient support for cost benefit analyses associated with cyber security mitigation actions. To address the need for better quantitative risk reduction models we surveyed previous quantitative risk assessment research; evaluated currently available tools; developed new quantitative techniques [17] [18]; implemented a prototype analysis tool to demonstrate how such a tool might be used; used the prototype to test a variety of underlying risk calculational engines (e.g. attack tree, attack graph); and identified technical and research needs. We concluded that significant gaps still exist and difficult research problems remain for quantitatively assessing the risk to control system components and networks, but that a useable quantitative risk reduction estimation tool is not beyond reach.

  3. Some Current Themes in Functional Analysis Research.

    Science.gov (United States)

    Vollmer, Timothy R.; Smith, Richard G.

    1996-01-01

    This article discusses clinical application of functional analysis in developmental disabilities, reviewing issues related to treatment logic and development. The article then approaches functional analysis as a research method, reviewing three areas of research: analysis of diverse response topographies, analysis of basic behavioral processes,…

  4. A Review on Researches of Active Tectonics——History, Progress and Suggestions1

    Institute of Scientific and Technical Information of China (English)

    Deng Qidong; Wen Xueze

    2009-01-01

    This paper reviews the history and progress of research on active tectonics in China and overseas. By giving a brief introduction on the history of active tectonic research in China and other countries, the paper sums up the process and development of quantitative investigation of active tectonics since the 1980s. The focus is on the main efforts and progress made in China on certain aspects of research, such as basic surveys and applied investigation of active tectonics, the study of theories related to regional active tectonics and their kinematics and geodynamics, surveys on coupling relations between deep and shallow structures, active fault surveys and prospecting and seismic hazard assessment in urban areas, as well as the efforts made using Quaternary geochronology. Furthermore, the paper looks back on Chinese quantitative investigation of active tectonics in China and sums up cognitions derived from studies on the determination of several basic and measurable parameters of active tectonics. These parameters include the length of fault and fault segmentation, coseismic slip and cumulative slip, fault slip rate, the sequence of paleoearthquake events and the time elapsed since the most recent event. At the same time, efforts and progress made in China on assessing the long-term seismic potential for active faults and evaluating the risk from potential active fault movement have been reviewed by summarizing research on developing theories, models, methods and the application of time-dependent seismic potential to prohabilistic assessment, magnitude estimation for potential earthquakes on active faults, and the forecast of potential risk caused by active fault movement. Finally, in consideration of the realities and problems in the research of active tectonics in China, the authors put forward several suggestions for issues worthy of more attention for further investigation in the future.

  5. LSP teacher education: Review of literature and suggestions for the research agenda

    Directory of Open Access Journals (Sweden)

    Helen Basturkmen

    2014-10-01

    Full Text Available Given the varied roles Language for Specific Purposes (LSP teachers typically play and the demanding nature of LSP teaching, the literature on teacher education for LSP is surprisingly limited. This paper examines the literature on LSP teacher education including literature on teacher education in English for Specific Purposes (ESP and English for Academic Purposes (EAP. The Introduction discusses the needs of LSP teachers, whose work typically involves investigating needs and specialist discourse, developing courses and materials as well as classroom teaching. It is argued that teacher needs are an important basis for determining content for LSP teacher education programmes and that further research is needed to identify these needs. Section 2 identifies themes in the existing literature. It focuses on two themes in particular, the role of specialised knowledge and suggestions for the content of the teacher education programme. Section 3 discusses models of teacher education with particular reference to LSP in-service contexts. Section 4 identifies gaps in the literature and suggests topics for the research agenda to develop understanding of the nature of LSP teaching expertise.

  6. Current developments in toxicological research on arsenic.

    Science.gov (United States)

    Bolt, Hermann M

    2013-01-01

    There is a plethora of recent publications on all aspects relevant to the toxicology of arsenic (As). Over centuries exposures to arsenic continue to be a major public health problem in many countries. In particular, the occurrence of high As concentrations in groundwater of Southeast Asia receives now much attention. Therefore, arsenic is a high-priority matter for toxicological research. Key exposure to As are (traditional) medicines, combustion of As-rich coal, presence of As in groundwater, and pollution due to mining activities. As-induced cardiovascular disorders and carcinogenesis present themselves as a major research focus. The high priority of this issue is now recognized politically in a number of countries, research funds have been made available. Also experimental research on toxicokinetics and toxicodynamics and on modes of toxic action is moving very rapidly. The matter is of high regulatory concern, and effective preventive measures are required in a number of countries.

  7. Loyalty Programmes : Current Knowledge and Research Directions

    NARCIS (Netherlands)

    Dorotic, Matilda; Bijmolt, Tammo H. A.; Verhoef, Peter C.

    2012-01-01

    Loyalty programmes (LPs) have increased in number and popularity, but their effects on customer behaviour remain equivocal, due to a lack of understanding of the drivers of LP effectiveness and insufficient generalizable conclusions across prior studies. This paper synthesizes current knowledge pert

  8. Current trends in chloroplast genome research

    African Journals Online (AJOL)

    USER

    2010-06-14

    Jun 14, 2010 ... organization and promising ability for transgenic expression. Therefore, cpDNA ... highly conserved in size, structure and gene content. (Olmstead and ... contain only 10% of the genes required for fully functional organelle whereas the ... concept (McFadden, 1999; Maliga, 2003; Howe, 2008). Currently 170 ...

  9. Loyalty Programmes : Current Knowledge and Research Directions

    NARCIS (Netherlands)

    Dorotic, Matilda; Bijmolt, Tammo H. A.; Verhoef, Peter C.

    Loyalty programmes (LPs) have increased in number and popularity, but their effects on customer behaviour remain equivocal, due to a lack of understanding of the drivers of LP effectiveness and insufficient generalizable conclusions across prior studies. This paper synthesizes current knowledge

  10. Loyalty Programmes : Current Knowledge and Research Directions

    NARCIS (Netherlands)

    Dorotic, Matilda; Bijmolt, Tammo H. A.; Verhoef, Peter C.

    2012-01-01

    Loyalty programmes (LPs) have increased in number and popularity, but their effects on customer behaviour remain equivocal, due to a lack of understanding of the drivers of LP effectiveness and insufficient generalizable conclusions across prior studies. This paper synthesizes current knowledge pert

  11. Preparing for the introduction of hospital autonomy in Laos: an assessment of current situation and suggestions for policy-making.

    Science.gov (United States)

    Geng, Jinsong; Yu, Hao; Chen, Yingyao

    2016-04-01

    The National Assembly of Lao People's Democratic Republic (Laos) approved the Health Sector Reform Strategy in 2012, which called for an assessment as to whether Laos should introduce hospital autonomy, and if so, in which ways. The purpose of this study is to assess the status quo of hospital governance in Laos and propose policy suggestions for hospital autonomy in the country. We formulated an analytic framework for hospital autonomy based on previous work by other researchers, collected qualitative data through key informant interviews and focus group discussions, and also performed secondary data analysis. Public hospitals in Laos enjoyed some informal autonomy with little accountability and Laos is facing key challenges of hospital governance. As a result, introducing hospital autonomy in Laos could bring risks, benefits and debates. Before Laos decides on granting autonomy to its public hospitals, we strongly suggest that the government do pilot in selected public hospitals with well-regulated governance framework first and conduct rigorous evaluations to examine whether the granted autonomy leads to the intended social goals of equity, quality, efficiency and sustainability. We recommend residual claimants should be monitored by the government and by the society with open and transparent approach, and active measures should be taken to improve performance and ensure social functions. The study findings may also provide some suggestions for low- and middle-income countries, which are contemplating the introduction of hospital autonomy in the public sector. Copyright © 2015 John Wiley & Sons, Ltd.

  12. Strategies for Sharing Scientific Research on Sea Level Rise: Suggestions from Stakeholder Focus Groups

    Science.gov (United States)

    DeLorme, D.; Hagen, S. C.; Stephens, S. H.

    2013-12-01

    This presentation reports results of focus groups with coastal resource managers on suggestions for effectively sharing sea level rise (SLR) scientific research with the public and other target audiences. The focus groups were conducted during three annual stakeholder workshops as an important and innovative component of an ongoing five-year multi-disciplinary NOAA-funded project, Ecological Effects of Sea Level Rise in the Northern Gulf of Mexico (EESLR-NGOM). The EESLR-NGOM project is assessing SLR risks to the natural and built environment along the Mississippi, Alabama, and Florida Panhandle coasts. The purpose was to engage stakeholders (e.g., coastal resource managers) in helping target, translate, and tailor the EESLR-NGOM project's scientific findings and emerging products so they are readily accessible, understandable, and useful. The focus groups provided insight into stakeholders' SLR informational and operational needs, solicited input on the project's products, and gathered suggestions for public communication and outreach. A total of three ninety-minute focus groups of between eight and thirteen participants each were conducted at annual workshops in Alabama, Florida, and Mississippi. The moderator asked a series of open-ended questions about SLR-related topics using an interview guide and encouraged participant interaction. All focus group audio-recordings were transcribed, and analyzed by carefully reading the 102 total pages of transcript data and identifying patterns and themes. Participants thought outreach about SLR impact and the EESLR-NGOM project scientific research/products was vital and acknowledged various communication challenges and opportunities. They identified three target audiences (local officials, general public, coastal resource managers themselves) that likely require different educational efforts and tools. Participants felt confident the EESLR-NGOM project products will benefit their resource planning and decision making and

  13. Current clinical research in orthodontics: a perspective.

    Science.gov (United States)

    Baumrind, Sheldon

    2006-10-01

    This essay explores briefly the approach of the Craniofacial Research Instrumentation Laboratory to the systematic and rigorous investigation of the usual outcome of orthodontic treatment in the practices of experienced clinicians. CRIL's goal is to produce a shareable electronic database of reliable, valid, and representative data on clinical practice as an aid in the production of an improved environment for truly evidence-based orthodontic treatment.

  14. Integrating Current Meteorological Research Through Club Fundraising

    Science.gov (United States)

    Gill, S. S.; Kauffman, C. M.

    2003-12-01

    Earth science programs whose focus is primarily an undergraduate education do not often have the funding to take students to very many conferences which could expose the student to new research as well as possible graduate programs and employment opportunities. Conferences also give the more enthusiastic and hardworking students a venue in which to present their research to the meteorological community. In addition, the California University services largely lower income counties, which make student attendance at conferences even more difficult even though the student in SW PA may be individually motivated. This issue is compounded by the fact that the Meteorology Concentration within the Earth Science department at Cal U is composed of only two full-time Professors, which limits the amount of research students can be exposed to within a classroom setting. New research ideas presented at conferences are thus an important mechanism for broadening what could be an isolated program. One way in which the meteorology program has circumvented the funding problem to a certain extent is through an active student club. With nearly 60 majors (3/4 of which are active in club activities, the meteorology club is able to execute a variety of fundraising activities. Money that is raised can then request from student services matching funds. Further money is given to clubs, which are very active not only in fundraising, but using that money for academic related activities. For the last 3 years the club budget has been in the neighborhood of \\$4500. The money has then been used to partially finance student registration and accommodation costs making conference attendance much more affordable. Normally 8-16 students attend conferences that they would otherwise not be able to attend without great expense. There are times when more than 16 students wish to attend, but travel arrangements prohibit more than 16. Moreover club money is also use to supplement student costs on a summer

  15. Sustainability in facilities management: an overview of current research

    DEFF Research Database (Denmark)

    Nielsen, Susanne Balslev; Sarasoja, Anna-Liisa; Ramskov Galamba, Kirsten

    2016-01-01

    the emerging sub-discipline of sustainable facilities management (SFM) on research, an overview of current studies is needed. The purpose of this literature review is to provide exactly this overview. Design/methodology/approach: This article identifies and examines current research studies on SFM through...... indicated that the current research varies in focus, methodology and application of theory, and it was concluded that the current research primary addresses environmental sustainability, whereas the current research which takes an integrated strategic approach to SFM is limited. The article includes lists...... of reviewed journals and articles to support the further development of SFM in research and practice. Research limitations/implications: The literature review includes literature from 2007 to 2012, to manage the analytical process within the project period. However, with the current categorisation...

  16. A brief, critical review of research on impaired control over alcohol use and suggestions for future studies.

    Science.gov (United States)

    Leeman, Robert F; Beseler, Cheryl L; Helms, Christa M; Patock-Peckham, Julie A; Wakeling, Vanessa A; Kahler, Christopher W

    2014-02-01

    Impaired control, defined as "a breakdown of an intention to limit consumption" (Heather et al. J Stud Alcohol 1993; 54, 701), has historically been considered an important aspect of addiction. Despite recognition of its importance to addiction and potential value as an early indicator of problem drinking risk, we argue that impaired control over alcohol use has not received sufficient research attention. In an effort to spark further research, the present critical review offers brief discussion of the current state of knowledge regarding impaired control and avenues for future research. Three main research areas are addressed: (i) epidemiology; (ii) measurement issues; and (iii) potential mechanisms underlying relationships between impaired control and subsequent problem drinking. Measurement issues include complexities involved in self-report assessment of impaired control, development and validation of human and animal laboratory models, and impaired control's relationship to other constructs (i.e., impulsivity and other difficulties with self-control; symptoms of dependence such as craving). We discuss briefly 2 potential mechanisms that may help to explain why some drinkers experience impaired control while others do not: neurobiological dysfunction and family history/genetics. Suggestions for future research are focused on ways in which the impaired control construct may enhance prediction of who might be at particular risk of subsequent problem drinking and to facilitate intervention to reduce problem alcohol use.

  17. Water Footprint of Cities: A Review and Suggestions for Future Research

    Directory of Open Access Journals (Sweden)

    Willa Paterson

    2015-06-01

    Full Text Available Cities are hotspots of commodity consumption, with implications for both local and systemic water resources. Water flows “virtually” into and out of cities through the extensive cross-boundary exchange of goods and services. Both virtual and real water flows are affected by water supply investments and urban planning decisions, which influence residential, commercial, and industrial development. This form of water “teleconnection” is being increasingly recognized as an important aspect of water decision-making. The role of trade and virtual water flows as an alternative to expanding a city’s “real” water supply is rarely acknowledged, with an emphasis placed instead on monotonic expansion of engineering potable water supplies. We perform a literature review of water footprint studies to evaluate the potential and importance of taking virtual flows into account in urban planning and policy. We compare and contrast current methods to assess virtual water flows. We also identify and discuss priorities for future research in urban water footprint analysis.

  18. Intelligent multimedia surveillance current trends and research

    CERN Document Server

    Atrey, Pradeep K; Cavallaro, Andrea

    2013-01-01

    Intelligent multimedia surveillance concerns the analysis of multiple sensing inputs including video and audio streams, radio-frequency identification (RFID), and depth data. These data are processed for the automated detection and tracking of people, vehicles, and other objects. The goal is to locate moving targets, to understand their behavior, and to detect suspicious or abnormal activities for crime prevention. Despite its benefits, there is societal apprehension regarding the use of such technology, so an important challenge in this research area is to balance public safety and privacy.

  19. The current status of Kartini research reactor

    Energy Technology Data Exchange (ETDEWEB)

    Tri Wulan Tjiptono; Syarip

    1998-10-01

    The Kartini reactor reached the first criticality on January 25, 1979. In the first three years, the reactor power is limited up to 50 kW thermal power and on July 1, 1982 has been increased to 100 kW. It has been used as experiments facility by researcher of Atomic Energy National Agency and students of the Universities. Three beam tubes used as experiments facilities, the first, is used as a neutron source for H{sub 2}O-Natural Uranium Subcritical Assembly, the second, is developed for neutron radiography facility and the third, is used for gamma radiography facility. The other facilities are rotary rack and two pneumatic transfer systems, one for delayed neutron counting system and the other for the new Neutron Activation Analysis (NAA) facility. The rotary rack used for isotope production for NAA purpose (for long time irradiation), the delayed neutron counting system used for analysis the Uranium contents of the ores and the new NAA is provided for short live elements analysis. In the last three years the Reactor Division has a joint use program with the Nuclear Component and Engineering Center in research reactor instrumentation and control development. (author)

  20. Nanofluid technology : current status and future research.

    Energy Technology Data Exchange (ETDEWEB)

    Choi, S. U.-S.

    1998-10-20

    Downscaling or miniaturization has been a recent major trend in modern science and technology. Engineers now fabricate microscale devices such as microchannel heat exchangers, and micropumps that are the size of dust specks. Further major advances would be obtained if the coolant flowing in the microchannels were to contain nanoscale particles to enhance heat transfer. Nanofluid technology will thus be an emerging and exciting technology of the 21st century. This paper gives a brief history of the Advanced Fluids Program at Argonne National Laboratory (ANL), discusses the concept of nanofluids, and provides an overview of the R and D program at ANL on the production, property characterization, and performance of nanofluids. It also describes examples of potential applications and benefits of nanofluids. Finally, future research on the fundamentals and applications of nanofluids is addressed.

  1. A SURVEY OF CURRENT RESEARCH ON CAPTCHA

    Directory of Open Access Journals (Sweden)

    Walid Khalifa Abdullah Hasan

    2016-06-01

    Full Text Available The internet has been playing an increasingly important role in our daily life, with the availability of many web services such as email and search engines. However, these are often threatened by attacks from computer programs such as bots. To address this problem, CAPTCHA (Completely Automated Public Turing Test to Tell Computers and Humans Apart was developed to distinguish between computer programs and human users. Although this mechanism offers good security and limits automatic registration to web services, some CAPTCHAs have several weaknesses which allow hackers to infiltrate the mechanism of the CAPTCHA. This paper examines recent research on various CAPTCHA methods and their categories. Moreover it discusses the weakness and strength of these types.

  2. Software Architecture and Framework for Programmable Logic Controllers: A Case Study and Suggestions for Research

    Directory of Open Access Journals (Sweden)

    E. George Walters

    2016-06-01

    Full Text Available Programmable Logic Controllers (PLCs are widely used for control and automation of machines and processes, so the quality of PLC software has a direct impact on production efficiency. This paper describes a PLC program for a food production line that was completely rewritten using a different software architecture and framework. The PLC hardware and the production line equipment were not changed, so this project provides an opportunity to quantify the impact of different PLC software architecture on production efficiency. The average number of cases of products produced per production hour during the first ten months with the new program was 6.1% higher than the average during the previous ten months with the old program. PLC software, unlike most other software, is often used by the end-user for troubleshooting. In this case, a relatively simple architecture and framework that favors the end-user significantly improved production efficiency over a more sophisticated architecture and framework that favors the software developer. Suggestions for further research on software architecture and framework are given.

  3. Current safety practices in nano-research laboratories in China.

    Science.gov (United States)

    Zhang, Can; Zhang, Jing; Wang, Guoyu

    2014-06-01

    China has become a key player in the global nanotechnology field, however, no surveys have specifically examined safety practices in the Chinese nano-laboratories in depth. This study reports results of a survey of 300 professionals who work in research laboratories that handle nanomaterials in China. We recruited participants at three major nano-research laboratories (which carry out research in diverse fields such as chemistry, material science, and biology) and the nano-chemistry session of the national meeting of the Chinese Chemical Society. Results show that almost all nano-research laboratories surveyed had general safety regulations, whereas less than one third of respondents reported having nanospecific safety rules. General safety measures were in place in most surveyed nano-research laboratories, while nanospecific protective measures existed or were implemented less frequently. Several factors reported from the scientific literature including nanotoxicology knowledge gaps, technical limitations on estimating nano-exposure, and the lack of nano-occupational safety legislation may contribute to the current state of affairs. With these factors in mind and embracing the precautionary principle, we suggest strengthening or providing nanosafety training (including raising risk awareness) and establishing nanosafety guidelines in China, to better protect personnel in the nano-workplace.

  4. Small karstic Dobra River (Croatia) suggested as natural laboratory for impactite research

    Science.gov (United States)

    Frančišković-Bilinski, Stanislav; Bilinski, Halka; Sikder, Arif M.

    2016-04-01

    An unexpected anomaly of magnetic susceptibility (MS) was observed in stream sediments of the upper course of the karstic Dobra River (Croatia). Preliminary results pointed to a possible impactite, formed by a shock event caused by a meteorite impact or by volcanic processes [1]. In addition to geophysical experiments, petrological and geochemical studies are reported [2, 3]. The multidisciplinary work for identification and confirmation of impact structure is still in progress. Results will be presented and the difficulties due to weathering and transport processes will be discussed and compared with recent literature [4, 5]. In reported results numerous evidences exist, which are in support of impact origin, such as vesicular glass with quench texture, ballen textures in the lechatelierite, presence of Troilite, etc. We suggest that the Dobra River from its source to the abyss in Ogulin (Upper Dobra) is a possible natural laboratory for studying processes of mixing between impactite material and fluvial sediments within a small area, including spherules exposed to water and in the overbank sediments. Especially the introduction of isotope studies in this research and enlargement of multinational team of experts are suggested. Literature: [1] Franči\\vsković-Bilinski, S., Bilinski, H., Scholger, R., Tomašić, N., Maldini, K. (2014): Magnetic spherules in sediments of the sinking karstic Dobra River (Croatia). Journal of soils and sediments 14(3), 600-614. [2] Franči\\vsković-Bilinski, S., Sikder, A.M., Bilinski, H., Castano, C.E., Garman, G.C. (2015): Traces of meteorite impact in the sediments of karstic Dobra River (Croatia). 15th International multidisciplinary scientific geoconference SGEM 2015 Conference proceedings, Vol. 1, 507-514. [3] Sikder, A.M., Franči\\vsković-Bilinski, S., Bilinski, H., Castano, C.E., Clifford, D.M., Turner, J.B., Garman, G.C. (2015): Petrographic analysis of the magnetic spherules from the sediments of karastic Dobra River

  5. Conceptual Models in Health Informatics Research: A Literature Review and Suggestions for Development

    OpenAIRE

    Gray, Kathleen; Sockolow, Paulina

    2016-01-01

    Background Contributing to health informatics research means using conceptual models that are integrative and explain the research in terms of the two broad domains of health science and information science. However, it can be hard for novice health informatics researchers to find exemplars and guidelines in working with integrative conceptual models. Objectives The aim of this paper is to support the use of integrative conceptual models in research on information and communication technologi...

  6. Viewpoint on the current status of researches on sepsis

    Directory of Open Access Journals (Sweden)

    Zheng-guo WANG

    2012-11-01

    Full Text Available Sepsis is a common complication after severe trauma and burn, and also one of the main causes of death. Recently, although some new progresses were seen in antibiotic therapy, the mortality of sepsis is still on the rise, and the death rate as a result of sepsis is higher than a total of that of prostate cancer, breast cancer and AIDS. Therefore, sepsis has obviously become one of the serious ailments threatening human health. The present paper introduced the international definition of sepsis, severe sepsis and septic shock, the current researches on diagnosis and therapy, and proposed that we should not only pay attention to pathogenesis and treatment, but also to sepsis prevention in sepsis researches, and we should try to find out the breakthrough in the interaction and dynamic balance between human being and pathogenic factors. Researches on the strategies to revert strong toxicity of infectious agents to non-toxic or weak pathogenic factors, and to conduct further research concerning biological characteristics of microorganisms and mechanism of drug resistance in order to render them to lose the drug resistance ability, or to increase its sensitivity to the drugs. The above suggested approaches might form the future strategies for preventing and controlling sepsis.

  7. A suggestion for future research on interface design of an Internet-based telemedicine system for the elderly.

    Science.gov (United States)

    Chuna, Young J; Patterson, Patrick E

    2012-01-01

    Telemedicine has emerged as an effective tool for providing high quality healthcare service and health-related information, especially in rural areas. Rural areas often have a larger elderly population with greater rates of preventable disease. These areas also have fewer medical resources and specialists, and have limited access to health services, all of which can influence overall health. An Internet-based telemedicine system can be one solution to provide the rural elderly with the proper health information when needed. The elderly obviously have limited capabilities compared with younger adults in the use of internet technology. However, the interfaces of the currently existing Internet-based telemedicine systems are not specifically developed for elderly users. This paper suggests future interface design research for an Internet-based telemedicine system specifically for the elderly.

  8. Current Issues in LPP Research and Their Impact on Society

    Science.gov (United States)

    Darquennes, Jeroen

    2013-01-01

    After a very broad description of what language policy and planning is about this paper presents an overview of some of the current preoccupations of researchers focusing on language policy and planning as one of the blooming fields of applied linguistics. The current issues in language policy and planning research that are dealt with include…

  9. [Scientific Research Policy for Health in Portugal: II - Facts and Suggestions].

    Science.gov (United States)

    Guerreiro, Cátia Sá; Hartz, Zulmira; Sambo, Luís; Conceição, Cláudia; Dussault, Gilles; Russo, Giuliano; Viveiros, Miguel; Silveira, Henrique; Pita Barros, Pedro; Ferrinho, Paulo

    2017-03-31

    After more than 40 years of democracy and 30 years of European integration, Portugal has bridged the research gap it had previously. However, when compared to global and European research policies, Portugal still has a long way go regarding investment in research and development. Health Research in Portugal has been managed by the Fundação para a Ciência e Tecnologia and the National Health Institute Doctor Ricardo Jorge, and it has not been a political priority, emphasized by the absence of a national scientific research plan for health, resulting in a weak coordination of actors in the field. The strategic guidelines of the 2004 - 2010 National Health Plan are what comes closest to a health research policy, but these were not implemented by the institutions responsible for scientific research for the health sector. Trusting that adopting a strategy of incentives to stimulate health research is an added-value for the Portuguese health system, the authors present five strategic proposals for research in health in Portugal.

  10. Post-Foundational Discourse Analysis: A Suggestion for a Research Program

    Directory of Open Access Journals (Sweden)

    Tomas Marttila

    2015-08-01

    Full Text Available Post-foundational discourse analysis, also labeled as Essex School in Discourse Analysis, has been observed to suffer from a considerable methodological deficit that limits its applicability in empirical research. The principal aim of this article is to overcome this methodological deficit by constructing the research program of the post-foundational discourse analysis that facilitates its operationalization in empirical research. In accordance with Imre LAKATOS (1970 and David HOWARTH (2004a, a research program is referred to an internally consistent and openly scrutinizable system of theoretical, methodological and phenomenal concepts that opens up the possibility to distinguish between the "negative" and the "positive" heuristics of empirical research. The first three sections develop the positive heuristics of the post-foundational discourse analysis by elucidating its theoretical foundations, methodological position and phenomenal framework. The concluding fourth section draws on the presented positive heuristics to outline the analytical stages and strategies of the post-foundational discourse analysis and discusses suitable methods for sampling and interpreting empirical data. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs150319

  11. Molecular pathology of solid tumours: some practical suggestions for translating research into clinical practice

    OpenAIRE

    Tomlinson, I P M; Ilyas, M

    2001-01-01

    “Molecular pathology” can be broadly defined as the use of genetic data, in addition to the standard pathological parameters, to optimise diagnosis and to indicate treatment and prognosis. The benefit to be gained from the exploitation of molecular techniques to provide additional information to aid patient management is potentially vast. Currently, molecular pathology is rarely used in clinical practice, although it is anticipated that it will eventually become a part of routine practice. Ho...

  12. Optimizing Quality of Care and Patient Safety in Malaysia: The Current Global Initiatives, Gaps and Suggested Solutions.

    Science.gov (United States)

    Jarrar, Mu'taman; Abdul Rahman, Hamzah; Don, Mohammad Sobri

    2015-10-20

    Demand for health care service has significantly increased, while the quality of healthcare and patient safety has become national and international priorities. This paper aims to identify the gaps and the current initiatives for optimizing the quality of care and patient safety in Malaysia. Review of the current literature. Highly cited articles were used as the basis to retrieve and review the current initiatives for optimizing the quality of care and patient safety. The country health plan of Ministry of Health (MOH) Malaysia and the MOH Malaysia Annual Reports were reviewed. The MOH has set four strategies for optimizing quality and sustaining quality of life. The 10th Malaysia Health Plan promotes the theme "1 Care for 1 Malaysia" in order to sustain the quality of care. Despite of these efforts, the total number of complaints received by the medico-legal section of the MOH Malaysia is increasing. The current global initiatives indicted that quality performance generally belong to three main categories: patient; staffing; and working environment related factors. There is no single intervention for optimizing quality of care to maintain patient safety. Multidimensional efforts and interventions are recommended in order to optimize the quality of care and patient safety in Malaysia.

  13. Future Directions in Adventure-based Therapy Research: Methodological Considerations and Design Suggestions.

    Science.gov (United States)

    Newes, Sandra L.

    2001-01-01

    More methodologically sound research in adventure therapy is needed if the field is to claim empirically-based efficacy as a treatment modality. Some considerations for conducting outcome studies in adventure therapy relate to standardization, multiple domain assessment, regression techniques, objective assessment of participant change, client and…

  14. Research Suggestions in the Design of a Global Graduate Business Program Delivered by Online Learning

    Science.gov (United States)

    Puderbaugh, Amy

    2015-01-01

    The purpose of this paper was to examine the unique areas of concern when establishing an eLearning program in the field of global business. A survey of eLearning and a global management subject matter appears. This paper identifies potential challenges in program design and raises practical concerns for future research. [For the full proceedings,…

  15. Research-Practice Integration in Real Practice Settings: Issues and Suggestions

    Science.gov (United States)

    Cheung, Monit; Ma, Anny K.; Thyer, Bruce A.; Webb, Ann E.

    2015-01-01

    At the National Bridging the Research and Practice Gap Symposium to discuss evidence-based practice (EBP) in social work, 150 participants attended five breakout groups to address real practice setting applications. These participants from social work academia and practice communities addressed issues and looked for solutions to promote…

  16. Some limitations on the external validity of psychotherapy efficacy studies and suggestions for future research.

    Science.gov (United States)

    Shean, Glenn D

    2012-01-01

    Increased emphasis on identifying empirically supported treatments (ESTs) has enhanced the scientific basis for psychotherapy practice, but uncritical acceptance of ESTs as the basis for credentialing and policy decisions risks stifling innovation and creativity in the field. There are limitations inherent in efficacy studies of psychotherapy that can constrain external validity. This article discusses several limitations on the external validity of efficacy studies, as well as other issues related to evaluating psychotherapy outcome research. These limitations and concerns include: 1) the practice of maximizing homogeneity by selecting participants diagnosed with a single Axis I disorder; 2) the practice of requiring manualized therapies for efficacy research; 3) the assumption that lasting and meaningful changes occur and can be assessed within a relatively short time frame; 4) the assumption that valid assessments of outcome can be conducted in randomized control trials studies without concern for researcher allegiance; and 5) the view that evidence of effectiveness from non-RCT design studies can be ignored. Finally, alternative research approaches for studying psychotherapy that can potentially supplement knowledge gained from efficacy studies and foster continued innovation and creativity in the field are discussed.

  17. Male or Female Therapists for Eating-Disordered Adolescents: Guidelines Suggested by Research and Practice.

    Science.gov (United States)

    Bilker, Larry

    1993-01-01

    Explores which therapist-patient gender matches facilitate most patient growth and avoid detriment to female patients with eating disorders. Distills relevant variables from literature on eating disorders, adolescence, transference and countertransference, and psychotherapy to suggest guidelines for effective matches. Sees therapist and patient…

  18. Male or Female Therapists for Eating-Disordered Adolescents: Guidelines Suggested by Research and Practice.

    Science.gov (United States)

    Bilker, Larry

    1993-01-01

    Explores which therapist-patient gender matches facilitate most patient growth and avoid detriment to female patients with eating disorders. Distills relevant variables from literature on eating disorders, adolescence, transference and countertransference, and psychotherapy to suggest guidelines for effective matches. Sees therapist and patient…

  19. Main Consequences of IFRS Adoption: Analysis of Existing Literature and Suggestions for Further Research

    Directory of Open Access Journals (Sweden)

    Isabel Maria Estima Costa Lourenço

    2015-08-01

    Full Text Available This study characterizes the results of scientific research on the effect of adopting the International Financial Reporting Standards (IFRS that have been published in the most prestigious scientific journals in the field of accounting at the international level and it identifies avenues for further research. Based on the analysis of a set of 67 articles published by the accounting journals that make up the Social Sciences Citation Index (SSCI, published between 2000 and 2013, it is concluded that, as a general rule, IFRS adoption has a positive effect on information quality, the capital market, analysts' ability to predict, comparability, and information use. Nevertheless, this effect depends on some factors, such as country's characteristics (namely, the enforcement level and companies' characteristics. Sharing rules is not, by itself, enough to create a common business language, and management incentives and institutional factors play a major role in framing the characteristics of financial reporting. Finally, some gaps are identified in the literature and avenues for further research are introduced.

  20. Recruiting Chinese Americans for dementia caregiver intervention research: suggestions for success.

    Science.gov (United States)

    Gallagher-Thompson, Dolores; Rabinowitz, Yaron; Tang, Paulette C Y; Tse, Collins; Kwo, Elizabeth; Hsu, Shannon; Wang, Peng-Chih; Leung, Laurie; Tong, Hui-Qi; Thompson, Larry W

    2006-08-01

    The purpose of this study was to compare the relative effectiveness of three recruitment modalities for enrolling Chinese-American and white family caregivers into research studies to evaluate intervention strategies. A total of 116 Chinese Americans and 134 whites were screened for eligibility to participate in one of two clinical intervention trials. Participants were recruited using: 1) media sources; 2) nonprofessional referral sources; or 3) professional referrals. Each participant was asked an open-ended question about how they became aware of the programs offered. A smaller proportion of Chinese Americans (39%) than whites (50%) who responded to recruiting strategies actually enrolled as subjects. There was a significant interaction between ethnicity and recruitment strategy. Chinese-American caregivers who were recruited by nonprofessional sources were less likely to enroll in the intervention studies than those who were recruited through media sources or professional referrals. Whites, on the other hand, were more likely to be recruited through nonprofessional sources than the other two. A consumer-oriented approach, which included direct face-to-face contact with key community leaders, generated the highest number of Chinese-American participants. Culture-specific factors such as trust-building with social service agencies, demonstrating genuine commitment to the well-being of the target community, and linguistic and ethnic matching between research staff and potential participants appear helpful to successful research recruitment in this rapidly increasing segment of dementia caregivers.

  1. Current status and future directions of research on facial attractiveness

    National Research Council Canada - National Science Library

    Kościński, Krzysztof

    2009-01-01

    The aim of the present paper was to evaluate the current state of knowledge on the perception of facial attractiveness and to assess the opportunity for research on poorly explored issues regarding facial preferences...

  2. Translational research in infectious disease: current paradigms and challenges ahead.

    Science.gov (United States)

    Fontana, Judith M; Alexander, Elizabeth; Salvatore, Mirella

    2012-06-01

    In recent years, the biomedical community has witnessed a rapid scientific and technologic evolution after the development and refinement of high-throughput methodologies. Concurrently and consequentially, the scientific perspective has changed from the reductionist approach of meticulously analyzing the fine details of a single component of biology to the "holistic" approach of broadmindedly examining the globally interacting elements of biological systems. The emergence of this new way of thinking has brought about a scientific revolution in which genomics, proteomics, metabolomics, and other "omics" have become the predominant tools by which large amounts of data are amassed, analyzed, and applied to complex questions of biology that were previously unsolvable. This enormous transformation of basic science research and the ensuing plethora of promising data, especially in the realm of human health and disease, have unfortunately not been followed by a parallel increase in the clinical application of this information. On the contrary, the number of new potential drugs in development has been decreasing steadily, suggesting the existence of roadblocks that prevent the translation of promising research into medically relevant therapeutic or diagnostic application. In this article, we will review, in a noninclusive fashion, several recent scientific advancements in the field of translational research, with a specific focus on how they relate to infectious disease. We will also present a current picture of the limitations and challenges that exist for translational research, as well as ways that have been proposed by the National Institutes of Health to improve the state of this field. Copyright © 2012 Mosby, Inc. All rights reserved.

  3. Research issues in Elderly patients: gaps in knowledge and suggested directions.

    Science.gov (United States)

    Walker, Robert; Fassett, Robert G; Morton, Rachael L

    2013-04-16

    Concentration of research is recommended in the following areas: Prospective studies of the appropriateness, relevance, timing and sustainability of dialysis in elderly patients Health related quality of life (HRQoL) in older patients choosing not to dialyse and in those choosing to dialyse with comparison to a matched population without renal disease Methods of communication of prognosis and factors affecting decision making Models of care - comparative studies to delineate how best to deliver renal supportive care Treatment preferences amongst indigenous patients Symptom control, focussing on those areas specific to the needs of renal patients. This article is protected by copyright. All rights reserved.

  4. Red Wolf (Canis rufus Recovery: A Review with Suggestions for Future Research

    Directory of Open Access Journals (Sweden)

    Michael J. Chamberlain

    2013-08-01

    Full Text Available By the 1970s, government-supported eradication campaigns reduced red wolves to a remnant population of less than 100 individuals on the southern border of Texas and Louisiana. Restoration efforts in the region were deemed unpromising because of predator-control programs and hybridization with coyotes. The U.S. Fish and Wildlife Service (USFWS removed the last remaining red wolves from the wild and placed them in a captive-breeding program. In 1980, the USFWS declared red wolves extinct in the wild. During 1987, the USFWS, through the Red Wolf Recovery Program, reintroduced red wolves into northeastern North Carolina. Although restoration efforts have established a population of approximately 70–80 red wolves in the wild, issues of hybridization with coyotes, inbreeding, and human-caused mortality continue to hamper red wolf recovery. We explore these three challenges and, within each challenge, we illustrate how research can be used to resolve problems associated with red wolf-coyote interactions, effects of inbreeding, and demographic responses to human-caused mortality. We hope this illustrates the utility of research to advance restoration of red wolves.

  5. Red Wolf (Canis rufus) Recovery: A Review with Suggestions for Future Research.

    Science.gov (United States)

    Hinton, Joseph W; Chamberlain, Michael J; Rabon, David R

    2013-08-13

    By the 1970s, government-supported eradication campaigns reduced red wolves to a remnant population of less than 100 individuals on the southern border of Texas and Louisiana. Restoration efforts in the region were deemed unpromising because of predator-control programs and hybridization with coyotes. The U.S. Fish and Wildlife Service (USFWS) removed the last remaining red wolves from the wild and placed them in a captive-breeding program. In 1980, the USFWS declared red wolves extinct in the wild. During 1987, the USFWS, through the Red Wolf Recovery Program, reintroduced red wolves into northeastern North Carolina. Although restoration efforts have established a population of approximately 70-80 red wolves in the wild, issues of hybridization with coyotes, inbreeding, and human-caused mortality continue to hamper red wolf recovery. We explore these three challenges and, within each challenge, we illustrate how research can be used to resolve problems associated with red wolf-coyote interactions, effects of inbreeding, and demographic responses to human-caused mortality. We hope this illustrates the utility of research to advance restoration of red wolves.

  6. Current Research on the Relative Effectiveness of Selected Media Characteristics.

    Science.gov (United States)

    Gulliford, Nancy L.

    The literature of research and theory on media, the psychology of learning, and the technology of instruction is reviewed. The focus is on discovering what is currently known about the intersection of these fields. Current thoughts and discoveries about brain structure and processing are discussed. The management of learning as a system is another…

  7. Design and array signal suggestion of array type pulsed eddy current probe for health monitoring of metal tubes

    Energy Technology Data Exchange (ETDEWEB)

    Shin, Young Kil [Dept. of Electrical Engineering, Kunsan National University, Kunsan (Korea, Republic of)

    2015-10-15

    An array type probe for monitoring metal tubes is proposed in this paper which utilizes peak value and peak time of a pulsed eddy current(PEC) signal. The probe consists of an array of encircling coils along a tube and the outside of coils is shielded by ferrite to prevent source magnetic fields from directly affecting sensor signals since it is the magnetic fields produced by eddy currents that reflect the condition of metal tubes. The positions of both exciter and sensor coils are consecutively moved automatically so that manual scanning is not necessary. At one position of send-receive coils, peak value and peak time are extracted from a sensor PEC signal and these data are accumulated for all positions to form an array type peak value signal and an array type peak time signal. Numerical simulation was performed using the backward difference method in time and the finite element method for spatial analysis. Simulation results showed that peak value increases and the peak appears earlier as the defect depth or length increases. The proposed array signals are shown to be excellent in reflecting the defect location as well as variations of defect depth and length within the array probe.

  8. Research Spotlight: Model suggests path to ending the ongoing Haitian cholera epidemic

    Science.gov (United States)

    Schultz, Colin

    2011-05-01

    Since early November 2010 a deadly cholera epidemic has been spreading across the Caribbean nation of Haiti, killing thousands of people and infecting hundreds of thousands. While infection rates are being actively monitored, health organizations have been left without a clear understanding of exactly how the disease has spread across Haiti. Cholera can spread through exposure to contaminated water, and the disease travels over long distances if an infected individual moves around the country. Using representations of these two predominant dispersion mechanisms, along with information on the size of the susceptible population, the number of infected individuals, and the aquatic concentration of the cholera-causing bacteria for more than 500 communities, Bertuzzo et al. designed a model that was able to accurately reproduce the progression of the Haitian cholera epidemic. (Geophysical Research Letters, doi:10.1029/2011GL046823, 2011)

  9. [Research progress in lampbrush chromosomes and some suggestions for their use in genetics teaching].

    Science.gov (United States)

    Fanguo, Chen; Qingqing, Li

    2016-02-01

    Lampbrush chromosomes (LBCs) are transient giant transcripts that exist at the diplotene stage of the first meiotic division in female gametocytes of almost all animals except mammals. LBCs are named for their lampbrush-like structure, however, they received the lowest research attention in studies of three classical cytogenetic chromosomes. They have been excellent models for studying the structure, organization, transcription, and transcriptional processing of chromosomes during meiosis. Here we briefly summarized these studies and LBCs forming mechanism and also discussed their possible functions, such as providing enough transcriptional products for embryonic development by oocytes LBCs or polyploidy demonstrated by previous reports. Finally, we discussed the possibility of introducing this typical case into our genetics teaching to inspire students' interest in genetics.

  10. Sex Differences in Spatial Performance in the Elderly: A Review of the Literature and Suggestions for Research

    Science.gov (United States)

    Cohen, Donna

    1977-01-01

    This paper reviews the literature on sex differences in spatial performance in older persons, proposes a theory of measurement, operational psychogenetic structuralism, for the analysis of sex differences in cognition, and suggests research directions relevant to educational gerontology. (Author)

  11. Current research projects on traffic conflicts technique studies.

    NARCIS (Netherlands)

    Hondel, M. van den & and Kraay, J.H.

    1979-01-01

    A review of current research concerning the development, evaluation and use of the traffic conflicts technique is presented. The 32 studies, selected from the IRRD data base, are listed alphabetically by names of countries and under countries by names of research organizations. The IRRD descriptions

  12. Educational Research in Mainland China: Current Situation and Developmental Trends

    Science.gov (United States)

    Sun, Miantao

    2011-01-01

    The influence of Confucian culture in Chinese Mainland China is reflected in the current situation and contextual trends of educational research content of educational thought of Confucianism, educational issues grounded on theoretical views of Confucianism, and the influence of the inclusiveness of Confucianism. In terms of research method, the…

  13. Educational Research in Mainland China: Current Situation and Developmental Trends

    Science.gov (United States)

    Sun, Miantao

    2011-01-01

    The influence of Confucian culture in Chinese Mainland China is reflected in the current situation and contextual trends of educational research content of educational thought of Confucianism, educational issues grounded on theoretical views of Confucianism, and the influence of the inclusiveness of Confucianism. In terms of research method, the…

  14. Construction ages of the Upton Stone Chamber: Preliminary findings and suggestions for future luminescence research

    Science.gov (United States)

    Mahan, Shannon; Martin, Frederick; Taylor, Cathy

    2015-01-01

    The Upton Chamber in Massachusetts, an earth-covered stone structure 3.4 meters (m) in diameter, with a corbelled stone dome, and a 4.3 m long entrance passageway, is studied with the aim of determining whether optically stimulated luminescence (OSL) dating methods can be used to establish the approximate construction date of the entranceway. Three samples, taken from soil behind the lowest stones in the wall of the entrance passageway, returned OSL ages between 385 and 660 years ago (or from 1625 A.D. to 1350 A.D.; using the year 2011 as the 0 year). One sample, taken below the bottom of the artifact layers in an archeological test pit in front of the chamber entrance, returned OSL ages between 650 and 880 years ago. A modern sample collected from a nearby fluvial channel returned an age between 55 and 175 years. The Upton Chamber OSL sampling results are challenging to interpret because there are mixtures in the samples of both younger and older grains that likely result from human modification, root or soil processes, animal bioturbation (i.e. ants and worms), and/or partial bleaching. The ages were determined using the lowest component of the finite mixture model as applied to a distribution of quartz grains. Further research may enable us to determine whether older components are of anthropomorphic or geological origin.

  15. A mini review of dolphin carbohydrate metabolism and suggestions for future research using exhaled air

    Directory of Open Access Journals (Sweden)

    Sam eRidgway

    2013-12-01

    Full Text Available In the 1960s, I explored some aspects of carbohydrate metabolism in healthy bottlenose dolphins (Tursiops truncatus. Their physiological picture resembled what had been described for hyperthyroid diabetics. Dolphins have elevated thyroid hormone turnover, and fasting dolphins maintain a relatively high level of plasma glucose. After dolphins ingest glucose, plasma levels remain high for many hours. Interestingly, plasma glucose must exceed 300 mg/dL (about twice as high as the human threshold before glucose appears in urine. Due to their diabetes-like states, trainability, and unique natural respiratory anatomy and physiology, dolphins may offer useful clues to metabolites in the breath that may be used to non-invasively monitor diabetes in humans. Dolphins take very rapid and deep breaths that are four or five times as deep as humans and other terrestrial mammals, making them ideal for physiological assessment using non-invasive exhaled air. Avenues for successfully identifying breath-based markers for metabolic disease and physiology in dolphins can be done with both modern technology and the evolutionarily advantageous canine nose. This review summarizes aspects of dolphin metabolism previously learned and offers new directions for diabetes research that may benefit both dolphin and human health.

  16. Image Information Retrieval: An Overview of Current Research

    Directory of Open Access Journals (Sweden)

    Abby A. Goodrum

    2000-01-01

    Full Text Available This paper provides an overview of current research in image information retrieval and provides an outline of areas for future research. The approach is broad and interdisciplinary and focuses on three aspects of image research (IR: text-based retrieval, content-based retrieval, and user interactions with image information retrieval systems. The review concludes with a call for image retrieval evaluation studies similar to TREC.

  17. Image Information Retrieval: An Overview of Current Research

    OpenAIRE

    Abby A. Goodrum

    2000-01-01

    This paper provides an overview of current research in image information retrieval and provides an outline of areas for future research. The approach is broad and interdisciplinary and focuses on three aspects of image research (IR): text-based retrieval, content-based retrieval, and user interactions with image information retrieval systems. The review concludes with a call for image retrieval evaluation studies similar to TREC.

  18. Current research and future directions in pattern identification: Results of an international symposium.

    Science.gov (United States)

    Lee, Myeong Soo; Lee, Ju Ah; Alraek, Terje; Bian, Zhao-Xiang; Birch, Stephen; Goto, Hirozo; Jung, Jeeyoun; Kao, Shung-Te; Moon, Sang-Kwan; Park, Bongki; Park, Kyung-Mo; You, Sooseong; Yun, Kyung-Jin; Zaslawski, Chris

    2016-12-01

    A symposium on pattern identification (PI) was held at the Korea Institute of Oriental Medicine (KIOM) on October 2, 2013, in Daejeon, South Korea. This symposium was convened to provide information on the current research in PI as well as suggest future research directions. The participants discussed the nature of PI, possible research questions, strategies and future international collaborations in pattern research. With eight presentations and an extensive panel discussion, the symposium allowed participants to discuss research methods in traditional medicine for PI. One speaker presented the topic, 'Clinical pattern differentiation and contemporary research in PI.' Two speakers presented current trends in research on blood stasis while the remaining five other delegates discussed the research methods and future directions of PI research. The participants engaged in in-depth discussions regarding the nature of PI, potential research questions, strategies and future international collaborations in pattern research.

  19. Paying research participants: a study of current practices in Australia.

    Science.gov (United States)

    Fry, C L; Ritter, A; Baldwin, S; Bowen, K J; Gardiner, P; Holt, T; Jenkinson, R; Johnston, J

    2005-09-01

    To examine current research payment practices and to inform development of clearer guidelines for researchers and ethics committees. Exploratory email based questionnaire study of current research participant reimbursement practices. A diverse sample of organisations and individuals were targeted. Australia. Contacts in 84 key research organisations and select electronic listservers across Australia. A total of 100 completed questionnaires were received with representations from a variety of research areas (for example, market, alcohol and drug, medical, pharmaceutical and social research). Open-ended and fixed alternative questions about type of research agency; type of research; type of population under study; whether payment is standard; amounts and mechanisms of payment; factors taken into account when deciding on payment practices; and whether payment policies exist. Reimbursement practice is highly variable. Where it occurs (most commonly for drug dependent rather than health professional or general population samples) it is largely monetary and is for time and out-of-pocket expenses. Ethics committees were reported to be often involved in decision making around reimbursement. Research subject payment practices vary in Australia. Researchers who do provide payments to research participants generally do so without written policy and procedures. Ethics committees have an important role in developing guidelines in this area. Specific guidelines are needed considering existing local policies and procedures; payment models and their application in diverse settings; case study examples of types and levels of reimbursement; applied definitions of incentive and inducement; and the rationale for diverse payment practices in different settings.

  20. Current states and perspectives of Czech educational research

    Directory of Open Access Journals (Sweden)

    Tomáš Janík

    2010-06-01

    Full Text Available The aim of the review study is to evaluate the current state of Czech educationalresearch and to offer possibilities of its further development. The paper has threeparts. In the first part, the author presents the context of the topic: the current changesin the financing of research and development in the Czech Republic; the avoiding ofthe term (social science is discussed along with the issue of institutional financing ofresearch and the various presently up-to-date methodologies of quality assessment inresearch. In the second part, the author analyses the current state of Czech educationalresearch – previous analyses of J. Pr°ucha, J. Mareš and E. Walterová and those carriedout by the Educational Research Centre are briefly summarised. In the third part, possibilitiesof further development of Czech educational research are offered. Developinga knowledge base of educational sciences is used as an example. First the nature andsubject of knowledge that is produced by research is analysed, then the difference betweenpedagogical research and research in education is discussed. Towards the end,relevant approaches are discussed along with research areas and types of knowledgeacquired by research.

  1. Current Research Therapeutic Strategies for Alzheimer's Disease Treatment

    Science.gov (United States)

    Folch, Jaume; Petrov, Dmitry; Ettcheto, Miren; Abad, Sonia; Sánchez-López, Elena; García, M. Luisa; Olloquequi, Jordi; Beas-Zarate, Carlos; Auladell, Carme; Camins, Antoni

    2016-01-01

    Alzheimer's disease (AD) currently presents one of the biggest healthcare issues in the developed countries. There is no effective treatment capable of slowing down disease progression. In recent years the main focus of research on novel pharmacotherapies was based on the amyloidogenic hypothesis of AD, which posits that the beta amyloid (Aβ) peptide is chiefly responsible for cognitive impairment and neuronal death. The goal of such treatments is (a) to reduce Aβ production through the inhibition of β and γ secretase enzymes and (b) to promote dissolution of existing cerebral Aβ plaques. However, this approach has proven to be only modestly effective. Recent studies suggest an alternative strategy centred on the inhibition of the downstream Aβ signalling, particularly at the synapse. Aβ oligomers may cause aberrant N-methyl-D-aspartate receptor (NMDAR) activation postsynaptically by forming complexes with the cell-surface prion protein (PrPC). PrPC is enriched at the neuronal postsynaptic density, where it interacts with Fyn tyrosine kinase. Fyn activation occurs when Aβ is bound to PrPC-Fyn complex. Fyn causes tyrosine phosphorylation of the NR2B subunit of metabotropic glutamate receptor 5 (mGluR5). Fyn kinase blockers masitinib and saracatinib have proven to be efficacious in treating AD symptoms in experimental mouse models of the disease. PMID:26881137

  2. Current Research Therapeutic Strategies for Alzheimer’s Disease Treatment

    Directory of Open Access Journals (Sweden)

    Jaume Folch

    2016-01-01

    Full Text Available Alzheimer’s disease (AD currently presents one of the biggest healthcare issues in the developed countries. There is no effective treatment capable of slowing down disease progression. In recent years the main focus of research on novel pharmacotherapies was based on the amyloidogenic hypothesis of AD, which posits that the beta amyloid (Aβ peptide is chiefly responsible for cognitive impairment and neuronal death. The goal of such treatments is (a to reduce Aβ production through the inhibition of β and γ secretase enzymes and (b to promote dissolution of existing cerebral Aβ plaques. However, this approach has proven to be only modestly effective. Recent studies suggest an alternative strategy centred on the inhibition of the downstream Aβ signalling, particularly at the synapse. Aβ oligomers may cause aberrant N-methyl-D-aspartate receptor (NMDAR activation postsynaptically by forming complexes with the cell-surface prion protein (PrPC. PrPC is enriched at the neuronal postsynaptic density, where it interacts with Fyn tyrosine kinase. Fyn activation occurs when Aβ is bound to PrPC-Fyn complex. Fyn causes tyrosine phosphorylation of the NR2B subunit of metabotropic glutamate receptor 5 (mGluR5. Fyn kinase blockers masitinib and saracatinib have proven to be efficacious in treating AD symptoms in experimental mouse models of the disease.

  3. Current pathways for epidemiological research in amyotrophic lateral sclerosis

    Science.gov (United States)

    FACTOR-LITVAK, PAM; AL-CHALABI, AMMAR; ASCHERIO, ALBERTO; BRADLEY, WALTER; CHÍO, ADRIANO; GARRUTO, RALPH; HARDIMAN, ORLA; KAMEL, FREYA; KASARSKIS, EDWARD; MCKEE, ANN; NAKANO, IMAHARU; NELSON, LORENE M.; EISEN, ANDREW

    2017-01-01

    Amyotrophic lateral sclerosis (ALS) is a rapidly progressive neurodegenerative disease. The current status of the epidemiology, challenges to its study, and novel study design options are discussed in this paper. We focus on recent results from large-scale population based prospective studies, case-control studies and population based registries, risk factors, and neuropathologic findings in chronic traumatic encephalomyelopathy. We identify areas of interest for future research, including time-trends in the incidence and prevalence of ALS; the meaning of lifetime risk; the phenotypic description of ALS; the definition of familial versus sporadic ALS, syndromic aspects of ALS; specific risk factors such as military service, life style factors such as smoking, the use of statins, and the presence of β-N-methylamino-L-alanine (BMAA), an excitotoxic amino acid derivative possibly produced by cyanobacteria found in almost every terrestrial and aquatic habitat; the emergence and disappearance of an endemic ALS in areas of the Pacific; and gene-environment interactions in the etiology of ALS. To move the epidemiology forward, we suggest using well-characterized cohorts of newly diagnosed ALS patients to identify risk and prognostic factors; storing biological material for future studies; building on the National ALS Registry as a resource of future studies; working in multidisciplinary consortia; and addressing the possible early life etiology of ALS. PMID:23678878

  4. The Development and Current State of Translation Process Research

    DEFF Research Database (Denmark)

    Lykke Jakobsen, Arnt

    2014-01-01

    The development and current state of translation process research ch Arnt Lykke Jakobsen Copenhagen Business School lInterest in process-oriented translation studies has been intense for the past almost half a century. Translation process research (TPR) is the label we have used to refer to a spe......The development and current state of translation process research ch Arnt Lykke Jakobsen Copenhagen Business School lInterest in process-oriented translation studies has been intense for the past almost half a century. Translation process research (TPR) is the label we have used to refer...... to a special descriptive, empirical, experimental approach to translation studies based on close, technology-supported observation of translational (micro)behaviour. Fundamentally, TPR is based on software which logs a translator’s keystrokes on a computer keyboard in time in combination with an eyetracker...

  5. Curating research data a handbook of current practice

    CERN Document Server

    Johnston, Lisa R

    2017-01-01

    Curating Research Data, Volume Two: A Handbook of Current Practice guides you across the data lifecycle through the practical strategies and techniques for curating research data in a digital repository setting. The data curation steps for receiving, appraising, selecting, ingesting, transforming, describing, contextualizing, disseminating, and preserving digital research data are each explored, and then supplemented with detailed case studies written by more than forty international practitioners from national, disciplinary, and institutional data repositories. The steps in this volume detail the sequential actions that you might take to curate a data set from receiving the data (Step 1) to eventual reuse (Step 8). Data curators, archivists, research data management specialists, subject librarians, institutional repository managers, and digital library staff will benefit from these current and practical approaches to data curation.

  6. [Physiotherapeutic care marketing research: current state-of-the art].

    Science.gov (United States)

    Babaskin, D V

    2011-01-01

    Successful introduction of modern technologies into the national health care systems strongly depends on the current pharmaceutical market situation. The present article is focused on the peculiarities of marketing research with special reference to physiotherapeutic services and commodities. Analysis of the structure and sequence of marketing research processes is described along with the methods applied for the purpose including their support by the use of Internet resources and technologies.

  7. Current research status of immunology in the genomic era

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    This review updates the current status of immunology research under the influence of genomics,both conceptually and technologically.It particularly highlights the advantages of employing the high-throughput and large-scale technology,the large genomic database,and bioinformatic power in the immunology research.The fast development in the fields of basic immunology,clinical immunology(tumor and infectious immunology) and vaccine designing is illustrated with respect to the successful usage of genomic strategy.We also speculate the future research directions of immunology in the era of genomics and post-genomics.

  8. Current research status of immunology in the genomic era

    Institute of Scientific and Technical Information of China (English)

    LI HaoWen; LI dinZhi; ZHAO GuoPing; WANG Ying

    2009-01-01

    This review updates the current status of immunology research under the influence of genomics, both conceptually and technologically. It particularly highlights the advantages of employing the high-throughput and large-scale technology, the large genomic database, and bioinformatic power in the immunology research. The fast development in the fields of basic immunology, clinical immunology (tumor and infectious immunology) and vaccine designing is illustrated with respect to the successful usage of genomic strategy. We also speculate the future research directions of immunology in the era of genomics and post-genomics.

  9. Changing Currents in Second Language Writing Research: A Colloquium.

    Science.gov (United States)

    Matsuda, Paul Kei; Canagarajah, A. Suresh; Harklau, Linda; Hyland, Ken; Warschauer, Mark

    2003-01-01

    This article is based on an invited colloqium on second language (L) writing presented at the 200 meeting of the American Association for Applied Linguistics. The colloquium featured five second language writing researchers two discussed some of the important currents that have shaped the field of second language writing. (Author/VWL)

  10. Current Status and Advancements in Research of Plantation Nutrient Cycling

    Institute of Scientific and Technical Information of China (English)

    LI Run; ZHANG Changshun; SUN Yongyu

    2006-01-01

    This paper introduces concepts and current research status of plantation nutrients cyclings, and analyzes main contents of plantation nutrients cycling as nutrients contents, accumulation and distribution of nutrients elements, understory species and forest litter. At the same time, the paper summarizes the problems in plantation nutrients cycling and its prospects.

  11. Communicative Language Testing: Current Issues and Future Research

    Science.gov (United States)

    Harding, Luke

    2014-01-01

    This article discusses a range of current issues and future research possibilities in Communicative Language Testing (CLT) using, as its departure point, the key questions which emerged during the CLT symposium at the 2010 Language Testing Forum. The article begins with a summary of the 2010 symposium discussion in which three main issues related…

  12. Lubbock Gin Lab - Current Research and Leaf Grade Issues

    Science.gov (United States)

    This presentation was given to a group of cotton gin managers and allied industry reps. Approximately 100 attendees were in the audience. A discussion of the current research conducted at the USDA ARS CPPRU Ginning Laboratory in Lubbock, TX was given along with a discussion of leaf grade issues and ...

  13. Cheerleading and Cynicism of Effective Mentoring in Current Empirical Research

    Science.gov (United States)

    Crutcher, Paul A.; Naseem, Samina

    2016-01-01

    This article presents the results of a review of current empirical research of effective practices in teacher mentoring. Compiling literature published since 2000 in peer-reviewed journals, we examine arguments for mentoring practices to improve teacher candidate and novice teacher experiences and skills. The emergent "effective"…

  14. The current status of research on resources recycling in Korea

    Energy Technology Data Exchange (ETDEWEB)

    Seo, Seung-Hee; Kuh, Sung-Eun; Kim, Dong-Su [Ewha Womans University, Seoul (Korea)

    1999-03-31

    The current domestic research status for resources recycling has been reviewed by surveying the technical and review papers reported to some academic journals. The surveyed articles were classified based upon several categories, including recycling fields according to the kinds of recyclable materials, applied recycling technologies, organizations where the research was conducted, and references according to publication year and region. The survey showed that the recycling of metallurgical waste is being studied most actively. Also, the investigation of fly ash recycling is surveyed to be actively conducted. In the aspect of recycling technologies, chemical technologies are shown to be more widely applied than physical ones. For research-conducting organizations, academic institutes have been more active in the research of recycling field compared with national/private research institutes and industries. In the reference survey, English-written articles and the articles published between 1991-1995 period are shown to be most referred. (author). 6 refs., 7 tabs., 8 figs.

  15. Consciousness and working memory: Current trends and research perspectives.

    Science.gov (United States)

    Velichkovsky, Boris B

    2017-07-27

    Working memory has long been thought to be closely related to consciousness. However, recent empirical studies show that unconscious content may be maintained within working memory and that complex cognitive computations may be performed on-line. This promotes research on the exact relationships between consciousness and working memory. Current evidence for working memory being a conscious as well as an unconscious process is reviewed. Consciousness is shown to be considered a subset of working memory by major current theories of working memory. Evidence for unconscious elements in working memory is shown to come from visual masking and attentional blink paradigms, and from the studies of implicit working memory. It is concluded that more research is needed to explicate the relationship between consciousness and working memory. Future research directions regarding the relationship between consciousness and working memory are discussed. Copyright © 2017 Elsevier Inc. All rights reserved.

  16. Animal models of frailty: current applications in clinical research.

    Science.gov (United States)

    Kane, Alice E; Hilmer, Sarah N; Mach, John; Mitchell, Sarah J; de Cabo, Rafael; Howlett, Susan E

    2016-01-01

    The ethical, logistical, and biological complications of working with an older population of people inherently limits clinical studies of frailty. The recent development of animal models of frailty, and tools for assessing frailty in animal models provides an invaluable opportunity for frailty research. This review summarizes currently published animal models of frailty including the interleukin-10 knock-out mouse, the mouse frailty phenotype assessment tool, and the mouse clinical frailty index. It discusses both current and potential roles of these models in research into mechanisms of frailty, interventions to prevent/delay frailty, and the effect of frailty on outcomes. Finally, this review discusses some of the challenges and opportunities of translating research findings from animals to humans.

  17. Control of antibiotic resistance in China must not be delayed: The current state of resistance and policy suggestions for the government, medical facilities, and patients.

    Science.gov (United States)

    Tang, Qi; Song, Peipei; Li, Jiajia; Kong, Fanlei; Sun, Long; Xu, Lingzhong

    2016-02-01

    Antibiotics are medicines used to prevent and treat bacterial infections. Antibiotic resistance occurs when bacteria change in response to the use of these medicines. Antibiotic resistance is rising to dangerously high levels in all parts of the world, leading to higher medical costs, prolonged hospital stays, and increased mortality. In the European Union alone, drug-resistant bacteria are estimated to cause 25,000 deaths and cost more than US$1.5 billion every year in healthcare expenses and productivity losses. The problems of antibiotic misuse and antibiotic resistance are quite serious in China. In 2015, results of a study by the State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences indicated that the total antibiotic usage in China in 2013 was approximately 162,000 tons, including human use (48%) and use in animals (52%). This amount accounted for about half of the antibiotic usage worldwide. The per-capita use of antibiotics in China is more than 5 times that in Europe and the United States. These data mean that China is one of the world's leading countries with serious problems in terms of antibiotic misuse and antibiotic resistance. The current article analyzes the current state and harms of antibiotic misuse and causes of antibiotic resistance in China. The Government needs to pay close attention to the issue of antibiotic resistance in China and formulate a strategy at the national level. Thus, the following suggestions are offered: i) The Chinese Government should implement policies that promote antibiotic research and development; ii) Medical facilities in China should create multidisciplinary teams (MDTs) and encourage early action by MDTs to control the spread of multi-drug-resistant bacteria (MDRB); iii) An intervention in the form of health education should target patients and accompanying family members (AFM) in China. In other words, antibiotic resistance is not a personal problem but an

  18. Some current challenges in research on air pollution and health.

    Science.gov (United States)

    Samet, Jonathan M

    2014-01-01

    This commentary addresses some of the diverse questions of current interest with regard to the health effects of air pollution, including exposure-response relationships, toxicity of inhaled particles and risks to health, multipollutant mixtures, traffic-related pollution, accountability research, and issues with susceptibility and vulnerability. It considers the challenges posed to researchers as they attempt to provide useful evidence for policy-makers relevant to these issues. This commentary accompanies papers giving the results from the ESCALA project, a multi-city study in Latin America that has an overall goal of providing policy-relevant results. While progress has been made in improving air quality, driven by epidemiological evidence that air pollution is adversely affecting public health, the research questions have become more subtle and challenging as levels of air pollution dropped. More research is still needed, but also novel methods and approaches to address these new questions.

  19. Artificial Neural Networks in Policy Research: A Current Assessment.

    Science.gov (United States)

    Woelfel, Joseph

    1993-01-01

    Suggests that artificial neural networks (ANNs) exhibit properties that promise usefulness for policy researchers. Notes that ANNs have found extensive use in areas once reserved for multivariate statistical programs such as regression and multiple classification analysis and are developing an extensive community of advocates for processing text…

  20. Artificial Neural Networks in Policy Research: A Current Assessment.

    Science.gov (United States)

    Woelfel, Joseph

    1993-01-01

    Suggests that artificial neural networks (ANNs) exhibit properties that promise usefulness for policy researchers. Notes that ANNs have found extensive use in areas once reserved for multivariate statistical programs such as regression and multiple classification analysis and are developing an extensive community of advocates for processing text…

  1. Business model innovation: Past research, current debates, and future directions

    DEFF Research Database (Denmark)

    Hossain, Mokter

    2017-01-01

    Purpose – The purpose of this paper is to provide state-of-the-art knowledge about business model innovation (BMI) and suggest avenues for future research. Design/methodology/approach – A systematic literature review approach was adopted with thematic analysis being conducted on 92 articles...

  2. A review on Bacopa monniera: Current research and future prospects

    Directory of Open Access Journals (Sweden)

    Gohil Kashmira

    2010-01-01

    Full Text Available In recent times, the use of herbal products has increased tremendously in the western world as well as in developed countries. Lately, one of the outstandingly important medicinal plants, widely used therapeutically in the orient and becoming increasingly popular in the west is Bacopa monniera, a well-known nootropic. The present review summarizes our current knowledge of pharmacological actions, preclinical and clinical studies, major bioactives, reported mechanisms of actions, clinical efficacy, safety and the possibility of interactions of the herb with the conventional drugs. Simultaneously, research updates as well as avenues for further research are also mentioned concerning the plant.

  3. SYRUPS: COMPOSITION, TECHNOLOGY, CURRENT STATE OF RESEARCH (REVIEW

    Directory of Open Access Journals (Sweden)

    M. E. Kim

    2014-01-01

    Full Text Available The overview data for the syrups formulation, including syrups for children, with synthetic substances were represented: assortment, composition, technological approach. The advantages and disadvantages of this dosage form were described. Details considered flavoring agents and other auxiliaries (stabilizers, preservatives, thickeners comprising syrups were closely examined. The issues of current research state of syrups for children were described.

  4. Research on scheme of applying ASON to current networks

    Science.gov (United States)

    Mao, Y. F.; Li, J. R.; Deng, L. J.

    2008-10-01

    Automatically Switched Optical Network (ASON) is currently a new and hot research subject in the world. It can provide high bandwidth, high assembly flexibility, high network security and reliability, but with a low management cost. It is presented to meet the requirements for high-throughput optical access with stringent Quality of Service (QoS). But as a brand new technology, ASON can not be supported by the traditional protocol software and network equipments. And the approach to build a new ASON network on the basis of completely abandoning the traditional optical network facilities is not desirable, because it costs too much and wastes a lot of network resources can also be used. So how to apply ASON to the current networks and realize the smooth transition between the existing network and ASON has been a serious problem to many network operators. In this research, the status in quo of ASON is introduced first and then the key problems should be considered when applying ASON to current networks are discussed. Based on this, the strategies should be complied with to overcome these key problems are listed. At last, the approach to apply ASON to the current optical networks is proposed and analyzed.

  5. Animal behavioral assessments in current research of Parkinson's disease.

    Science.gov (United States)

    Asakawa, Tetsuya; Fang, Huan; Sugiyama, Kenji; Nozaki, Takao; Hong, Zhen; Yang, Yilin; Hua, Fei; Ding, Guanghong; Chao, Dongman; Fenoy, Albert J; Villarreal, Sebastian J; Onoe, Hirotaka; Suzuki, Katsuaki; Mori, Norio; Namba, Hiroki; Xia, Ying

    2016-06-01

    Parkinson's disease (PD), a neurodegenerative disorder, is traditionally classified as a movement disorder. Patients typically suffer from many motor dysfunctions. Presently, clinicians and scientists recognize that many non-motor symptoms are associated with PD. There is an increasing interest in both motor and non-motor symptoms in clinical studies on PD patients and laboratory research on animal models that imitate the pathophysiologic features and symptoms of PD patients. Therefore, appropriate behavioral assessments are extremely crucial for correctly understanding the mechanisms of PD and accurately evaluating the efficacy and safety of novel therapies. This article systematically reviews the behavioral assessments, for both motor and non-motor symptoms, in various animal models involved in current PD research. We addressed the strengths and weaknesses of these behavioral tests and their appropriate applications. Moreover, we discussed potential mechanisms behind these behavioral tests and cautioned readers against potential experimental bias. Since most of the behavioral assessments currently used for non-motor symptoms are not particularly designed for animals with PD, it is of the utmost importance to greatly improve experimental design and evaluation in PD research with animal models. Indeed, it is essential to develop specific assessments for non-motor symptoms in PD animals based on their characteristics. We concluded with a prospective view for behavioral assessments with real-time assessment with mobile internet and wearable device in future PD research.

  6. 海南省观赏水族行业的发展前景及对策%Current Situation of Decorative Fishery in Hainan and Development Suggestions

    Institute of Scientific and Technical Information of China (English)

    张希; 杨宁; 黄海

    2012-01-01

    An important part of recreational fisheries is decorative fishery,which will become a trend in China.Decorative fishery is also an important direction of development in the building process of Hainan international tourism Island.On the base of the deep-going analysis about the current situation of decorative fishery development in Hainan,the main questions of decorative fish cultivation and market were found.At the same time many suggestions were brought up,such as exploiting the biological resources of Hainan Island;Strengthening the efforts of research institutes aquaculture R & D;introducing new varieties of ornamental species;Strengthening market management etc,which will benefit the rational utilization of tropical biological resources and increase a whole competitive advantage of Hainan decorative fishery industry.%观赏水族业是休闲渔业的重要组成部分,海南具有大力发展热带观赏水族行业的潜力。对海南省观赏水族市场进行深入调查,分析和总结海南省观赏水族行业的发展现状和存在的问题,提出发挥海南区位优势、挖掘本地热带生物资源、加强科研力量、引进国外观赏水族新品种、加强产业引导和市场管理等建议,促进热带生物资源的合理利用和观赏水族业结构的多元化,增加海南省观赏水族业的整体竞争优势。

  7. Current status of oral health research in Africa: an overview.

    Science.gov (United States)

    Kanoute, Aïda; Faye, Daouda; Bourgeois, Denis

    2012-12-01

    Research in oral health contributes effectively to decisions and strategies aimed at improving the oral health of populations. Further contributions to enhance current knowledge of oral health in Africa are required. The principal objective of this study was to produce an analysis of oral health research published from different subregions of Africa and to estimate bilateral and multilateral international cooperation in oral health research during the period 2005-2010. The PubMed database was searched for published articles on topics related to oral health in Africa. A total of 935 oral health-related articles were retrieved during April and May 2011. Publications emanating from Nigeria and South Africa accounted for a striking 68% of all oral health-related material published from Africa during the study period. Researchers from 30 different countries had participated in collaboration on at least one published article. A total of 262 journals had published at least one item examining oral health in Africa, but only 29 journals had published more than seven articles. These 29 journals accounted for 66% of all published material and induced non-African reviews (26%) and African reviews (40%). This study shows strong variation among countries in the production of articles on oral health whereby rich countries produce greater quantities of published research and poorer nations more frequently develop research partnerships with other countries. © 2012 FDI World Dental Federation.

  8. Incorporating current research into formal higher education settings using Astrobites

    Science.gov (United States)

    Sanders, Nathan E.; Kohler, Susanna; Faesi, Chris; Villar, Ashley; Zevin, Michael

    2017-10-01

    A primary goal of many undergraduate- and graduate-level courses in the physical sciences is to prepare students to engage in scientific research or to prepare students for careers that leverage skillsets similar to those used by research scientists. Even for students who may not intend to pursue a career with these characteristics, exposure to the context of applications in modern research can be a valuable tool for teaching and learning. However, a persistent barrier to student participation in research is familiarity with the technical language, format, and context that academic researchers use to communicate research methods and findings with each other: the literature of the field. Astrobites, an online web resource authored by graduate students, has published brief and accessible summaries of more than 1300 articles from the astrophysical literature since its founding in 2010. This article presents three methods for introducing students at all levels within the formal higher education setting to approaches and results from modern research. For each method, we provide a sample lesson plan that integrates content and principles from Astrobites, including step-by-step instructions for instructors, suggestions for adapting the lesson to different class levels across the undergraduate and graduate spectrum, sample student handouts, and a grading rubric.

  9. What recent research on diagrams suggests about learning with rather than learning from visual representations in science

    Science.gov (United States)

    Tippett, Christine D.

    2016-03-01

    The move from learning science from representations to learning science with representations has many potential and undocumented complexities. This thematic analysis partially explores the trends of representational uses in science instruction, examining 80 research studies on diagram use in science. These studies, published during 2000-2014, were located through searches of journal databases and books. Open coding of the studies identified 13 themes, 6 of which were identified in at least 10% of the studies: eliciting mental models, classroom-based research, multimedia principles, teaching and learning strategies, representational competence, and student agency. A shift in emphasis on learning with rather than learning from representations was evident across the three 5-year intervals considered, mirroring a pedagogical shift from science instruction as transmission of information to constructivist approaches in which learners actively negotiate understanding and construct knowledge. The themes and topics in recent research highlight areas of active interest and reveal gaps that may prove fruitful for further research, including classroom-based studies, the role of prior knowledge, and the use of eye-tracking. The results of the research included in this thematic review of the 2000-2014 literature suggest that both interpreting and constructing representations can lead to better understanding of science concepts.

  10. Gender relations and health research: a review of current practices

    Directory of Open Access Journals (Sweden)

    Bottorff Joan L

    2011-12-01

    Full Text Available Abstract Introduction The importance of gender in understanding health practices and illness experiences is increasingly recognized, and key to this work is a better understanding of the application of gender relations. The influence of masculinities and femininities, and the interplay within and between them manifests within relations and interactions among couples, family members and peers to influence health behaviours and outcomes. Methods To explore how conceptualizations of gender relations have been integrated in health research a scoping review of the existing literature was conducted. The key terms gender relations, gender interactions, relations gender, partner communication, femininities and masculinities were used to search online databases. Results Through analysis of this literature we identified two main ways gender relations were integrated in health research: a as emergent findings; and b as a basis for research design. In the latter, gender relations are included in conceptual frameworks, guide data collection and are used to direct data analysis. Conclusions Current uses of gender relations are typically positioned within intimate heterosexual couples whereby single narratives (i.e., either men or women are used to explore the influence and/or impact of intimate partner gender relations on health and illness issues. Recommendations for advancing gender relations and health research are discussed. This research has the potential to reduce gender inequities in health.

  11. Current frontiers and future directions of telecoupling research

    Science.gov (United States)

    Liu, J.

    2016-12-01

    The world has been increasingly interconnected over long distances though processes such as international trade, migration, telecommunication, and disease spread. However, previous studies often focused on socioeconomic or environmental issues of distant processes. While these studies have generated useful information for individual disciplines, integrating socioeconomic and environmental information is essential for holistic understanding of complex global challenges and unbiased decision making to address the challenges. To advance integrated research, the framework of telecoupling (socioeconomic and environmental interactions over distances) has been developed to explicitly address both socioeconomic and environmental issues simultaneously. Although the framework is relatively new, it has already been applied to tackle a variety of globally important issues, such as food security, water resources, energy sustainability, land use, international trade (e.g., food, forest products, energy, wildlife, industrial products), species invasion, investment, ecosystem services, conservation, information dissemination, and tourism. These applications have identified many important research gaps (e.g. spillover systems) and hidden linkages (e.g. feedbacks) among distant areas of the world with profound implications for sustainable development, ecosystem health, and human well-being. While working with telecoupling presents more challenges than focusing only on disciplinary issues, support from funding agencies has helped accelerate research on telecoupling and more efforts are being aimed at framework quantification and operationalization. The presenter will provide an overview of the current frontiers, discuss future research directions, and highlight emerging opportunities and challenges in telecoupling research and governance.

  12. Current research in child and adolescent bipolar disorder.

    Science.gov (United States)

    Demeter, Christine A; Townsend, Lisa D; Wilson, Michael; Findling, Robert L

    2008-01-01

    Although recently more research has considered children with bipolar disorder than in the past, much controversy still surrounds the validity of the diagnosis. Furthermore, questions remain as to whether or not childhood expressions of bipolarity are continuous with adult manifestations of the illness. In order to advance current knowledge of bipolar disorders in children, researchers have begun to conduct phenomenological, longitudinal, treatment, and neuroimaging studies in youths who exhibit symptoms of bipolar illness, as well as offspring of parents with bipolar disorders. Regardless of the differences between research groups regarding how bipolar disorder in children is defined, it is agreed that pediatric bipolarity is a serious and pernicious illness. With early intervention during the period of time in which youths are exhibiting subsyndromal symptoms of pediatric bipolarity, it appears that the progression of the illness to the more malignant manifestation of the disorder may be avoided. This paper will review what is currently known and what still is left to learn about clinically salient topics that pertain to bipolar disorder in children and adolescents.

  13. Survey of biomass gasification. Volume III. Current technology and research

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-04-01

    This survey of biomass gasification was written to aid the Department of Energy and the Solar Energy Research Institute Biological and Chemical Conversion Branch in determining the areas of gasification that are ready for commercialization now and those areas in which further research and development will be most productive. Chapter 8 is a survey of gasifier types. Chapter 9 consists of a directory of current manufacturers of gasifiers and gasifier development programs. Chapter 10 is a sampling of current gasification R and D programs and their unique features. Chapter 11 compares air gasification for the conversion of existing gas/oil boiler systems to biomass feedstocks with the price of installing new biomass combustion equipment. Chapter 12 treats gas conditioning as a necessary adjunct to all but close-coupled gasifiers, in which the product is promptly burned. Chapter 13 evaluates, technically and economically, synthesis-gas processes for conversion to methanol, ammonia, gasoline, or methane. Chapter 14 compiles a number of comments that have been assembled from various members of the gasifier community as to possible roles of the government in accelerating the development of gasifier technology and commercialization. Chapter 15 includes recommendations for future gasification research and development.

  14. An Action Research into International Masters Program in Practicing Management (IMPM: Suggesting Refraction to Complement Reflection for Management Learning in the Global Knowledge Economy

    Directory of Open Access Journals (Sweden)

    Tunc D. MEDENI

    2008-05-01

    Full Text Available International Masters Program in Practicing Management (IMPM is a collaborative effort by major business schools and corporations around the world, balancing practical and academic issues within pedagogy of “experienced reflection”. This action research into the IMPM aims to explain the IMPM and its importance for the global knowledge economy, as well as identify and improve the current limitations of the program. As a result, we hope to provide specific suggestions for the IMPM practice and general guidelines for business education. Our suggestions are based upon a framework of “refraction” that follows a methodology of action research and pluralistic knowledge science epistemology, a critique of management learning, and a literature review on (critical reflection, as well as our findings about the IMPM practice. Also, critically reviewing Mintzberg and other authors’ ideas on management learning and IMPM specifically supports our discussion in this paper.

  15. Novel shifts in memory research and their impact on the legal process: introduction to the special issue on memory formation and suggestibility in the legal process.

    Science.gov (United States)

    Otgaar, Henry; Sauerland, Melanie; Petrila, John P

    2013-01-01

    The functioning and frailties of memory are frequently at the centerpiece of much expert testimony about the reliability of eyewitness accounts. Although we have much knowledge about how false memories and suggestibility can affect testimonies, the contributions in this special issue show that when using a sound theoretical framework, novel directions in this field can surface. The papers in this issue can broadly be divided into contributions that are related to: (1) the exact determinants of false memory and suggestibility; (2) new paradigms in legal psychology; (3) positive consequences of memory illusions; and (4) developmental false memory research. Collectively, these contributions have the potential to provide novel shifts in memory research and push this field beyond its current boundaries.

  16. Current status of research and related activities in NAA application

    Energy Technology Data Exchange (ETDEWEB)

    Ab. Khalik bin Haji Wood [Malaysia Institute for Nuclear Technology Research, Bangi, Selangor (Malaysia)

    1999-10-01

    Current activities of Analytical Chemistry Group of MINT (Malaysia Institute for Nuclear Technology Research) laboratory for elemental analysis of trace amounts in environmental samples such as air particulate matter (on air filter), soils/sediments, water, flora/fauna, oil sludge/waste sludge, and tailing/blasting slag and others, utilizing particularly NAA (Neutron Activation Analysis) method are reviewed. The laboratory participates in the IAEA-organized Interlaboratory Comparison Studies to ensure the analytical system. Other activities include analytical chemistry services with ICP-mass spectrometry and GC/GCMS to compliment the NAA and, moreover, air and marine pollution studies with participation in the UNDP/RCA/IAEA project. (S. Ohno)

  17. The Pioneering Work of Enrico Morselli (1852-1929) in Light of Modern Scientific Research on Hypnosis and Suggestion.

    Science.gov (United States)

    Bartolucci, Chiara; Lombardo, Giovanni Pietro

    2017-01-01

    This article examines research on hypnosis and suggestion, starting with the nineteenth-century model proposed by Enrico Morselli (1852-1929), an illustrious Italian psychiatrist and psychologist. The authors conducted an original psychophysiological analysis of hypnosis, distancing the work from the neuropathological concept of the time and proposing a model based on a naturalistic approach to investigating mental processes. The issues investigated by Morselli, including the definition of hypnosis and analysis of specific mental processes such as attention and memory, are reviewed in light of modern research. From the view of modern neuroscientific concepts, some problems that originated in the nineteenth century still appear to be present and pose still-open questions.

  18. On Unsaturated Soil Mechanics - Personal Views on Current Research

    Science.gov (United States)

    Pande, G. N.; Pietruszczak, S.

    2015-09-01

    This paper presents the authors' personal views on current research being conducted by various research groups around the world in the broad area of mechanics of unsaturated geomaterials in general and soils in particular. The topic is of interest to a wide spectrum of scientists and engineers working in diverse areas such as geology and geophysics, powder technology, agricultural, petroleum, chemical, geotechnical, civil, environmental and nuclear engineering. Even if we restrict ourselves to civil, geotechnical and environmental engineering, it is noted that a plethora of hypotheses as well as a number of empirical and semi-empirical relations have been introduced for describing the mechanics of unsaturated porous media. However, many of these proposed advances as well as methods of testing may lack sound theoretical basis.

  19. Current Research and Management of Ovarian Cancer in China

    Institute of Scientific and Technical Information of China (English)

    GUMeijiao; SHIWei

    2002-01-01

    Ovarian cancer is ne of the most lethal malignant tumors in China,represents the third most common cancer after cervical cancer and endometrial cancer,and the first leading cause of death from hynaecological cancers.Due to the lack of effective screening strategies and the absence of symptoms in early-stage of disease,over 70% of patients present at an advanced stage.Despite the advances in surgical techniques and conventional chemotheraphy,the prognosis of ovarian cancer has not been improved significantly,and indeed the long-term survival for patients with advanced disease does not exceed 20%.The aetiology of ovarian cancer temains poorly understood.In China,the major focus of research is to clarify the mechanism underlying ovarian cancer,develop more effective life-saving diagnostic and therapeutic measures,and undertake more population-based studies.This article summarizes current research,diagnosis and management of ovarian cancer in China.

  20. Bulk Glassy Alloys: Historical Development and Current Research

    Directory of Open Access Journals (Sweden)

    Akihisa Inoue

    2015-06-01

    Full Text Available This paper reviews the development of current research in bulk glassy alloys by focusing on the trigger point for the synthesis of the first bulk glassy alloys by the conventional mold casting method. This review covers the background, discovery, characteristics, and applications of bulk glassy alloys, as well as recent topics regarding them. Applications of bulk glassy alloys have been expanding, particularly for Fe-based bulk glassy alloys, due to their unique properties, high glass-forming ability, and low cost. In the near future, the engineering importance of bulk glassy alloys is expected to increase steadily, and continuous interest in these novel metallic materials for basic science research is anticipated.

  1. On Unsaturated Soil Mechanics – Personal Views on Current Research

    Directory of Open Access Journals (Sweden)

    Pande G.N.

    2015-09-01

    Full Text Available This paper presents the authors’ personal views on current research being conducted by various research groups around the world in the broad area of mechanics of unsaturated geomaterials in general and soils in particular. The topic is of interest to a wide spectrum of scientists and engineers working in diverse areas such as geology and geophysics, powder technology, agricultural, petroleum, chemical, geotechnical, civil, environmental and nuclear engineering. Even if we restrict ourselves to civil, geotechnical and environmental engineering, it is noted that a plethora of hypotheses as well as a number of empirical and semi-empirical relations have been introduced for describing the mechanics of unsaturated porous media. However, many of these proposed advances as well as methods of testing may lack sound theoretical basis.

  2. Astrobites: Engaging Undergraduate Science Majors with Current Astrophysical Research

    Science.gov (United States)

    Zevin, Michael; Astrobites

    2017-01-01

    Astrobites is a graduate-student organization that publishes an online astrophysical literature blog (astrobites.com). The purpose of the site is to make current astrophysical research accessible to and exciting for undergraduate physical science majors and astronomy enthusiasts, and the site now hosts an archive of over 1300 posts summarizing recent astrophysical research. In addition, Astrobites presents posts on career guidance, practical 'how-to' articles, conference summaries, and astronomy news. Astrobites has an average of more than 1000 pageviews per day and reaches not only its target audience of undergraduates, but also graduate students and professionals within astronomy, astronomy enthusiasts, and educators. As we enter our seventh year of successful blogging, we share here the most up-to-date summary of our organization, readership, and growth.

  3. The International Permafrost Association: current initiatives for cryospheric research

    Science.gov (United States)

    Schollaen, Karina; Lewkowicz, Antoni G.; Christiansen, Hanne H.; Romanovsky, Vladimir E.; Lantuit, Hugues; Schrott, Lothar; Sergeev, Dimitry; Wei, Ma

    2015-04-01

    The International Permafrost Association (IPA), founded in 1983, has as its objectives to foster the dissemination of knowledge concerning permafrost and to promote cooperation among persons and national or international organizations engaged in scientific investigation and engineering work on permafrost. The IPA's primary responsibilities are convening International Permafrost Conferences, undertaking special projects such as preparing databases, maps, bibliographies, and glossaries, and coordinating international field programs and networks. Membership is through adhering national or multinational organizations or as individuals in countries where no Adhering Body exists. The IPA is governed by its Executive Committee and a Council consisting of representatives from 26 Adhering Bodies having interests in some aspect of theoretical, basic and applied frozen ground research, including permafrost, seasonal frost, artificial freezing and periglacial phenomena. This presentation details the IPA core products, achievements and activities as well as current projects in cryospheric research. One of the most important core products is the circumpolar permafrost map. The IPA also fosters and supports the activities of the Global Terrestrial Network on Permafrost (GTN-P) sponsored by the Global Terrestrial Observing System, GTOS, and the Global Climate Observing System, GCOS, whose long-term goal is to obtain a comprehensive view of the spatial structure, trends, and variability of changes in the active layer thickness and permafrost temperature. A further important initiative of the IPA are the biannually competitively-funded Action Groups which work towards the production of well-defined products over a period of two years. Current IPA Action Groups are working on highly topical and interdisciplinary issues, such as the development of a regional Palaeo-map of Permafrost in Eurasia, the integration of multidisciplinary knowledge about the use of thermokarst and permafrost

  4. Nanomaterials in Lubricants: An Industrial Perspective on Current Research

    Directory of Open Access Journals (Sweden)

    Boris Zhmud

    2013-11-01

    Full Text Available This paper presents an overview on the use of various classes of nanomaterials in lubricant formulations. The following classes of nanomaterials are considered: fullerenes, nanodiamonds, ultradispersed boric acid and polytetrafluoroethylene (PTFE. Current advances in using nanomaterials in engine oils, industrial lubricants and greases are discussed. Results of numerous studies combined with formulation experience of the authors strongly suggest that nanomaterials do indeed have potential for enhancing certain lubricant properties, yet there is a long way to go before balanced formulations are developed.

  5. Aespoe hard rock laboratory. Current research projects 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-31

    In 1986 SKB decided to construct the Aespoe Hard Rock Laboratory (HRL) in order to provide an opportunity for research, development and demonstration in a realistic and undisturbed underground rock environment down to the depth planned for the future deep repository. The focus of current and future work is on development and testing of site characterization methods, verification of models describing the function of the natural and engineered barriers and development, testing, and demonstration of repository technology. The program has been organised so that all important steps in the development of a repository are covered, in other words the Aespoe HRL constitutes a `dress rehearsal` for the Swedish deep geological repository for spent fuel and other long-lived waste. Geoscientific investigations on Aespoe and nearby islands began in 1986. Aespoe was selected as the site for the laboratory in 1988. Construction of the facility, which reaches a depth of 460 m below the surface, began in 1990 and was completed in 1995. A major milestone had been reached in 1996 with the completion of the pre-investigation and construction phases of the Aespoe HRL. The comprehensive research conducted has permitted valuable development and verification of site characterization methods applied from the ground surface, boreholes, and underground excavations. The results of this research are summarised in the book `Aespoe Hard Rock Laboratory - 10 years of Research` published by SKB in 1996. The Operating Phase of the Aespoe HRL began in 1995 and is expected to continue for 15-20 years, that is until the first stage of the development of the Swedish deep geological repository for spent nuclear fuel is expected to be completed. A number of research projects were initiated at the start of the Operating Phase. Most of these projects have made substantial progress since then and important results have been obtained. The purpose of this brochure is to provide a brief presentation of the

  6. Support for international agricultural research: current status and future challenges.

    Science.gov (United States)

    Zeigler, Robert S; Mohanty, Samarendu

    2010-11-30

    The success of the first Green Revolution in the form of abundant food supplies and low prices over the past two decades has diverted the world's attention from agriculture to other pressing issues. This has resulted in lower support for the agricultural research work primarily undertaken by the 15 research centers of the Consultative Group on International Agricultural Research (CGIAR). The total support in real dollars for most of the last three decades has been more or less flat although the number of centers increased from 4 to 15. However, since 2000, the funding situation has improved for the CGIAR centers, with almost all the increase coming from grants earmarked for specific research projects. Even for some centers such as the International Rice Research Institute (IRRI), the downward trend continued as late as 2006 with the budget in real dollars reaching the 1978 level of support. The recent food crisis has renewed the call for a second Green Revolution by revitalizing yield growth to feed the world in the face of growing population and a shrinking land base for agricultural use. The slowdown in yield growth because of decades of neglect in agricultural research and infrastructure development has been identified as the underlying reason for the recent food crisis. For the second Green Revolution to be successful, the CGIAR centers will have to play a complex role by expanding productivity in a sustainable manner with fewer resources. Thus, it is crucial to examine the current structure of support for the CGIAR centers and identify the challenges ahead in terms of source and end use of funds for the success of the second Green Revolution. The objective of this paper is to provide a historical perspective on the support to the CGIAR centers and to examine the current status of funding, in particular, the role of project-specific grants in rebuilding capacity of these centers. The paper will also discuss the nature of the support (unrestricted vs. project

  7. Alaskan Peninsula Cenozoic stratigraphy: stratigraphic sequences and current research

    Energy Technology Data Exchange (ETDEWEB)

    Allison, R.C.; Armentrout, J.M.

    1985-04-01

    Geology of the Alaska Peninsula-Island Arc and Continental Margin, by C.A. Burk, is the principal reference for stratigraphic studies on the Alaska Peninsula. Burk mapped the Phanerozoic stratigraphy and provided a geologic history and structural interpretation of the area between Wide Bay and Unimak Island. Cenozoic rocks were mapped as three unconformity-bounded sequences. Recognition of specific formations was difficult due to similarity of lithofacies, isolated outcrops, rapid facies changes, and alteration and burial by young volcanics. Consequently, megafossil assemblages were relied upon to facilitate correlations between study areas. The three unconformity-bounded Cenozoic sequences are: (1) the Paleogene Beaver Bay Group consisting of three formations: the dominantly nonmarine Tolstoi Formation, the dominantly marine Stepovak Formation, and the volcanic Meshik Formation. Current work suggests these units are at least in part coeval facies of late Paleocene through Oligocene age. (2) The Neogene Bear Lake Formation consisting of the lower Unga Conglomerate Member and an unnamed upper member. Rapid facies changes and incorrect reports of fossil occurrence have resulted in confusion of stratigraphic relationships within this sequence of middle to late Miocene age. (3) A late Neogene informally defined upper sequence consisting of interbedded marginal marine, coastal-plain, and volcanic facies. Current work suggests this sequence is Pliocene through Pleistocene in age.

  8. Transcranial Direct Current Stimulation: Considerations for Research in Adolescent Depression

    Directory of Open Access Journals (Sweden)

    Jonathan C. Lee

    2017-06-01

    Full Text Available Adolescent depression is a prevalent disorder with substantial morbidity and mortality. Current treatment interventions do not target relevant pathophysiology and are frequently ineffective, thereby leading to a substantial burden for individuals, families, and society. During adolescence, the prefrontal cortex undergoes extensive structural and functional changes. Recent work suggests that frontolimbic development in depressed adolescents is delayed or aberrant. The judicious application of non-invasive brain stimulation techniques to the prefrontal cortex may present a promising opportunity for durable interventions in adolescent depression. Transcranial direct current stimulation (tDCS applies a low-intensity, continuous current that alters cortical excitability. While this modality does not elicit action potentials, it is thought to manipulate neuronal activity and neuroplasticity. Specifically, tDCS may modulate N-methyl-d-aspartate receptors and L-type voltage-gated calcium channels and effect changes through long-term potentiation or long-term depression-like mechanisms. This mini-review considers the neurobiological rationale for developing tDCS protocols in adolescent depression, reviews existing work in adult mood disorders, surveys the existing tDCS literature in adolescent populations, reviews safety studies, and discusses distinct ethical considerations in work with adolescents.

  9. Livestock in biomedical research: history, current status and future prospective.

    Science.gov (United States)

    Polejaeva, Irina A; Rutigliano, Heloisa M; Wells, Kevin D

    2016-01-01

    Livestock models have contributed significantly to biomedical and surgical advances. Their contribution is particularly prominent in the areas of physiology and assisted reproductive technologies, including understanding developmental processes and disorders, from ancient to modern times. Over the past 25 years, biomedical research that traditionally embraced a diverse species approach shifted to a small number of model species (e.g. mice and rats). The initial reasons for focusing the main efforts on the mouse were the availability of murine embryonic stem cells (ESCs) and genome sequence data. This powerful combination allowed for precise manipulation of the mouse genome (knockouts, knockins, transcriptional switches etc.) leading to ground-breaking discoveries on gene functions and regulation, and their role in health and disease. Despite the enormous contribution to biomedical research, mouse models have some major limitations. Their substantial differences compared with humans in body and organ size, lifespan and inbreeding result in pronounced metabolic, physiological and behavioural differences. Comparative studies of strategically chosen domestic species can complement mouse research and yield more rigorous findings. Because genome sequence and gene manipulation tools are now available for farm animals (cattle, pigs, sheep and goats), a larger number of livestock genetically engineered (GE) models will be accessible for biomedical research. This paper discusses the use of cattle, goats, sheep and pigs in biomedical research, provides an overview of transgenic technology in farm animals and highlights some of the beneficial characteristics of large animal models of human disease compared with the mouse. In addition, status and origin of current regulation of GE biomedical models is also reviewed.

  10. Current research in transcultural psychiatry in the Nordic countries.

    Science.gov (United States)

    Ekblad, Solvig; Kastrup, Marianne Carisius

    2013-12-01

    This article discusses major themes in recent transcultural psychiatric research in the Nordic countries from 2008 to 2011: (a) epidemiological studies of migration, (b) indigenous populations, and (c) quality of psychiatric care for migrants. Over the past several decades, the populations of the Nordic countries, Denmark, Finland, Norway, and Sweden, which were relatively homogeneous, have become increasingly culturally diverse. Many migrants to Nordic countries have been exposed to extreme stress, such as threats of death and/or torture and other severe social adversities before, during, and after migration, with potential effects on their physical, mental, social, and spiritual health. Growing interest in transcultural issues is reflected in the level of scientific research and clinical activity in the field by Nordic physicians, psychologists, social scientists, demographers, medical anthropologists, as well as other clinicians and policy planners. Research includes work with migrants and indigenous minorities in the Nordic countries, as well as comparisons with mental health in postconflict countries. We conclude by suggesting future directions for transcultural psychiatry research and providing guidelines for the education and training of future clinicians in the Nordic countries.

  11. Towards Bi-Inclusive Policies: Suggestions Based on Research on Dutch Same-Sex Attracted Young People.

    Science.gov (United States)

    van Lisdonk, Jantine; Keuzenkamp, Saskia

    2017-01-01

    Dutch national LGBT policies are not bi-inclusive and this study provides suggestions for improvement, based on empirical research. Attention for bisexuality in policy appears simply to pay lip service and to endorse the construction of sexual orientation as a hetero/homo binary. The outcomes of our survey (n = 1449) and in-depth interviews (n = 38) of Dutch same-sex attracted young people suggest that special attention for bisexual people is warranted. Compared to exclusively same-sex attracted participants, the equally both-sex attracted participants scored worse on openness about their sexual attraction, visibility discomfort, perceived acceptance, and suicide attempts. Unique issues for bisexual-identified young people were identified as follows: marginalization of bisexuality; difficulty expressing bisexuality, particularly in relationships; and a lack of bisexual or bi-inclusive communities. These issues were all related to the hetero/homo binary and mononormativity. Suggested implications for more bi-inclusive policies focus on awareness of marginalization and invisibility of bisexuality, biphobia, community and capacity building, and comprehensive sexuality and gender education. Furthermore, rather than policies focusing on sameness, a comprehensive diversity perspective on sexuality and gender offers more space for bisexuality. This may be particularly relevant for young people who are exploring their sexuality and developing a sense of their sexual self.

  12. The current status of environmental health research in Australia.

    Science.gov (United States)

    Gowland, Angela; Cook, Angus; Heyworth, Jane

    2012-01-01

    At present, the extent of environmental health research in Australia is unclear and there are no recent overarching reviews of national publications on the subject. This study investigates the current status of environmental health research in Australia using a bibliometric analysis. Three databases (Medline, Web of Science, and AUSTHealth) were used to access original, peer-reviewed journal articles with Australian data published between 1 January 2001 and 11 June 2010. A total of 337 articles from 174 different journal titles were used in the analysis and were classified according to 15 pre-determined environmental health areas. The highest number of articles related to water health and resources (66 articles), exposure to hazardous chemicals (57 articles), and air pollution including indoor air (58 articles). These areas made up 54% of the total publication output over the past 10 years. The amount of environmental health research published in Australia over the past 10 years, and the topics explored in these studies, is comparable to that of other countries of similar socio-economic status.

  13. Precision viticulture in Brazil: Current research status on wine grape

    Directory of Open Access Journals (Sweden)

    Miele Alberto

    2014-01-01

    Full Text Available Technologies associated to precision viticulture (PV are not currently used by Brazilian growers. To overcome this situation, a research is being carried out since 2011 in a vineyard of Merlot using a wide range of PV technologies. During this period, several PV research activities were performed which will be concluded in a couple of years. Therefore, final results depend on further variable evaluation which should be done by means of geostatistic, Geographic Information Systems and Principal Component Analysis. This paper briefly presents a series of methodological procedures used in different ways to attain the objective of this research project. In the sequence, it describes one final result and nine partial ones. Morphological and physicochemical analyses of soil showed that the vineyards are established on three taxonomic classes of soil – Argissolo, Cambissolo and Neossolo −, which are formed by ten mapping units. The partial results are mainly related to the utilization of GIS, modeling and must and wine composition of five mapping units; however they show results of only one year. With the complete set of analyses, data should be spatialized and maps prepared. Then, it will be possible to recommend different practices to each soil type and to aid oenologists to direct wines to a specific quality pattern.

  14. Current status of silicon materials research for photovoltaic applications

    Energy Technology Data Exchange (ETDEWEB)

    Ciszek, T F

    1985-04-01

    The desire for high solar cell efficiencies has been a strong factor in determining the course of recent silicon crystal growth research efforts for photovoltaics. This review, therefore, focuses on single-crystal, dislocation-free ingot growth methods (Czochralski growth, float zoning, and cold crucible growth) and on sheet growth technologies, generally multicrystalline, that have achieved moderately high (>13.5%) laboratory-scale efficiencies. These include dendritic web growth, growth from capillary dies, edge-supported pulling, ribbon-against-drop growth, and a recent technique termed crucible-free horizontal growth. Silicon ribbon crystals provide a favorable geometry and require no wafering, but they contain defects that limit solar cell performance. Growth processes, their current status, and cell efficiencies are discussed. Silicon material process steps before and after crystal growth are described, and the advantages of silicon are presented.

  15. Current Debates in Corporate Social Responsibility: An Agenda for Research

    Directory of Open Access Journals (Sweden)

    David Crowther

    2007-06-01

    Full Text Available Corporate Social Responsibility (CSR has a particular prominence at this point in time, featuring heavily in the discourses of both academe and business. The understanding of what is meant by CSR continues to evolve as a consensus is reached. Nevertheless some important debates continue – or are commencing – which need to be resolved. It is the purpose of this paper to highlight these as some of the current debates within the CSR community – and hence form a significant part of an agenda for research in the area. Specifically we focus upon three key areas for the management of business, namely setting standards for reporting, identifying and implementing sustainable practice, and the management of risk.

  16. The distribution of P-values in medical research articles suggested selective reporting associated with statistical significance.

    Science.gov (United States)

    Perneger, Thomas V; Combescure, Christophe

    2017-07-01

    Published P-values provide a window into the global enterprise of medical research. The aim of this study was to use the distribution of published P-values to estimate the relative frequencies of null and alternative hypotheses and to seek irregularities suggestive of publication bias. This cross-sectional study included P-values published in 120 medical research articles in 2016 (30 each from the BMJ, JAMA, Lancet, and New England Journal of Medicine). The observed distribution of P-values was compared with expected distributions under the null hypothesis (i.e., uniform between 0 and 1) and the alternative hypothesis (strictly decreasing from 0 to 1). P-values were categorized according to conventional levels of statistical significance and in one-percent intervals. Among 4,158 recorded P-values, 26.1% were highly significant (P P ≥ 0.001 to P ≥ 0.01 to P ≥ 0.05). We noted three irregularities: (1) high proportion of P-values P-values equal to 1, and (3) about twice as many P-values less than 0.05 compared with those more than 0.05. The latter finding was seen in both randomized trials and observational studies, and in most types of analyses, excepting heterogeneity tests and interaction tests. Under plausible assumptions, we estimate that about half of the tested hypotheses were null and the other half were alternative. This analysis suggests that statistical tests published in medical journals are not a random sample of null and alternative hypotheses but that selective reporting is prevalent. In particular, significant results are about twice as likely to be reported as nonsignificant results. Copyright © 2017 Elsevier Inc. All rights reserved.

  17. Munchausen by Internet: Current Research and Future Directions

    Science.gov (United States)

    Taylor, Jacqui

    2012-01-01

    Background The Internet has revolutionized the health world, enabling self-diagnosis and online support to take place irrespective of time or location. Alongside the positive aspects for an individual’s health from making use of the Internet, debate has intensified on how the increasing use of Web technology might have a negative impact on patients, caregivers, and practitioners. One such negative health-related behavior is Munchausen by Internet. Objective Munchausen by Internet occurs when medically well individuals fake recognized illnesses in virtual environments, such as online support groups. This paper focuses on the aspect of Munchausen by Internet in which individuals actively seek to disrupt groups for their own satisfaction, which has not yet been associated with the wider phenomena of Internet trolls (users who post with the intention of annoying someone or disrupting an online environment). Methods A wide-ranging review was conducted to investigate the causes and impacts of online identity deception and Munchausen by Internet drawing on academic research and case studies reported online and in the media. Results The limited research relating to motivation, opportunity, detection, effects, and consequences of Munchausen by Internet is highlighted and it is formally linked to aspects of trolling. Case studies are used to illustrate the phenomenon. What is particularly worrying is the ease with which the deception can be carried out online, the difficulty in detection, and the damaging impact and potential danger to isolated victims. Conclusions We suggest ways to deal with Munchausen by Internet and provide advice for health group facilitators. We also propose that Munchausen by Internet and Munchausen by Internet trolling should be formally acknowledged in a revised version of the Diagnostic and Statistical Manual DSM-5. This will assist in effectively identifying and minimizing the growth of this behavior as more people seek reassurance and support

  18. Current Research Status of KHNP for Site Risk

    Energy Technology Data Exchange (ETDEWEB)

    Oh, Kyemin; Jeon, Ho-Jun; Bahng, Ki-In; Na, Jang-Hwan [KHNP CRI, Daejeon (Korea, Republic of)

    2016-10-15

    In Korea, by the geographical characteristics, many Nuclear Power Plants (NPPs) have been constructed and operated at a single site. This is above average level or number of plants per site in the world. For this reason, the public concerns for the safety of nuclear facilities increased after Fukushima Daiichi accident. As a result, comprehensive risk assessment and management for the site which have multi-unit NPPs were strongly asked. Currently, to solve it, many researches and projects has carried out by various Korean companies, research centers, and regulatory authorities. In this paper, R and D plans of KHNP for multi-unit risk were summarized. Firstly, the needs of multi-unit PSA were reviewed. R and D activities and plans of KHNP were summarized in the last part. In this paper, we summarized the R and D plans of KHNP for assessing the multi-unit risk. Currently, multi-unit risk or multi-unit PSA are important and practical issues in both nuclear industry and national energy policy. After Fukushima accident, several countries stopped the construction and the operation of NPPs, other countries which is maintaining the NPPs are being strongly asked to assess the risk for multi-unit NPPs at the same site. Because of Korean geographical characteristics, the number of NPPs which are above average level or number of plants per site in the world is being constructed and operated at a single site. The population density nearby each site is considered to be higher than that of other countries.

  19. [Video game and internet addiction. The current state of research].

    Science.gov (United States)

    Rehbein, F; Mößle, T; Arnaud, N; Rumpf, H-J

    2013-05-01

    The use of interactive screen media is widespread and for some users leads to pathological symptoms that are phenomenologically similar to signs of addictive disorders. Addictive use of computer games and other Internet applications, such as social media can be distinguished. In the past standard criteria to classify this new disorder were lacking. In DSM-5, nine criteria are proposed for diagnosing Internet gaming disorder. The focus is currently on video games as most studies have been done in this field. Prevalence estimations are difficult to interpret due to the lack of standard diagnostic measures and result in a range of the frequency of Internet addiction between 1 % and 4.2 % in the general German population. Rates are higher in younger individuals. For computer game addiction prevalence rates between 0.9 % and 1.7  % can be found in adolescents. Despite substantial comorbidity among those affected current research points to addictive media use as a stand-alone disorder.

  20. Current Status and Research into Overcoming Limitations of Capsule Endoscopy.

    Science.gov (United States)

    Kwack, Won Gun; Lim, Yun Jeong

    2016-01-01

    Endoscopic investigation has a critical role in the diagnosis and treatment of gastrointestinal (GI) diseases. Since 2001, capsule endoscopy (CE) has been available for small-bowel exploration and is under continuous development. During the past decade, CE has achieved impressive improvements in areas such as miniaturization, resolution, and battery life. As a result, CE is currently a first-line tool for the investigation of the small bowel in obscure gastrointestinal bleeding and is a useful alternative to wired enteroscopy. Nevertheless, CE still has several limitations, such as incomplete examination and limited diagnostic and therapeutic capabilities. To resolve these problems, many groups have suggested several models (e.g., controlled CO2 insufflation system, magnetic navigation system, mobile robotic platform, tagging and biopsy equipment, and targeted drug-delivery system), which are in development. In the near future, new technological advances will improve the capabilities of CE and broaden its spectrum of applications not only for the small bowel but also for the colon, stomach, and esophagus. The purpose of this review is to introduce the current status of CE and to review the ongoing development of solutions to address its limitations.

  1. Advancing Implementation of Evidence-Based Public Health in China: An Assessment of the Current Situation and Suggestions for Developing Regions.

    Science.gov (United States)

    Shi, Jianwei; Jiang, Chenghua; Tan, Duxun; Yu, Dehua; Lu, Yuan; Sun, Pengfei; Pan, Ying; Zhang, Hanzhi; Wang, Zhaoxin; Yang, Beilei

    2016-01-01

    Objective. Existing research shows a serious scarcity of EBPH practice in China and other developing regions; as an exploratory study, this study aimed to assess the current EBPH implementation status in Shanghai of China qualitatively. Methods. Using semistructured key informant interviews, we examined the status of and impediments to the lagging EBPH in China. Data were analyzed based on the Consolidated Framework for Implementation Research (CFIR). Results. Chinese public health practitioners knew more about evidence-based medicine but less about EBPH. The situation was worse in community healthcare centers. Participants perceived that evidence sources were limited and the quality of evidence was low. Concerning the inner setting factors, the structural characteristics, networks and communications, implementation climate, and leadership engagement were confronted with many problems. Among the outer setting factors, external government policies and incentives and low patient compliance were the key problems. Additionally, public health practitioners in Shanghai lacked sufficient awareness of EBPH. Furthermore, the current project-based EBPH lacks a systematic implementation system. Conclusions. Existing practical perspectives on EBPH indicate a lag in the advocacy of this new ideology in China. It would be advisable for healthcare institutions to take the initiative to explore feasible and multiple methods of EBPH promotion.

  2. Advancing Implementation of Evidence-Based Public Health in China: An Assessment of the Current Situation and Suggestions for Developing Regions

    Directory of Open Access Journals (Sweden)

    Jianwei Shi

    2016-01-01

    Full Text Available Objective. Existing research shows a serious scarcity of EBPH practice in China and other developing regions; as an exploratory study, this study aimed to assess the current EBPH implementation status in Shanghai of China qualitatively. Methods. Using semistructured key informant interviews, we examined the status of and impediments to the lagging EBPH in China. Data were analyzed based on the Consolidated Framework for Implementation Research (CFIR. Results. Chinese public health practitioners knew more about evidence-based medicine but less about EBPH. The situation was worse in community healthcare centers. Participants perceived that evidence sources were limited and the quality of evidence was low. Concerning the inner setting factors, the structural characteristics, networks and communications, implementation climate, and leadership engagement were confronted with many problems. Among the outer setting factors, external government policies and incentives and low patient compliance were the key problems. Additionally, public health practitioners in Shanghai lacked sufficient awareness of EBPH. Furthermore, the current project-based EBPH lacks a systematic implementation system. Conclusions. Existing practical perspectives on EBPH indicate a lag in the advocacy of this new ideology in China. It would be advisable for healthcare institutions to take the initiative to explore feasible and multiple methods of EBPH promotion.

  3. Advancing Implementation of Evidence-Based Public Health in China: An Assessment of the Current Situation and Suggestions for Developing Regions

    Science.gov (United States)

    Shi, Jianwei; Tan, Duxun; Yu, Dehua; Lu, Yuan; Sun, Pengfei; Pan, Ying; Zhang, Hanzhi; Yang, Beilei

    2016-01-01

    Objective. Existing research shows a serious scarcity of EBPH practice in China and other developing regions; as an exploratory study, this study aimed to assess the current EBPH implementation status in Shanghai of China qualitatively. Methods. Using semistructured key informant interviews, we examined the status of and impediments to the lagging EBPH in China. Data were analyzed based on the Consolidated Framework for Implementation Research (CFIR). Results. Chinese public health practitioners knew more about evidence-based medicine but less about EBPH. The situation was worse in community healthcare centers. Participants perceived that evidence sources were limited and the quality of evidence was low. Concerning the inner setting factors, the structural characteristics, networks and communications, implementation climate, and leadership engagement were confronted with many problems. Among the outer setting factors, external government policies and incentives and low patient compliance were the key problems. Additionally, public health practitioners in Shanghai lacked sufficient awareness of EBPH. Furthermore, the current project-based EBPH lacks a systematic implementation system. Conclusions. Existing practical perspectives on EBPH indicate a lag in the advocacy of this new ideology in China. It would be advisable for healthcare institutions to take the initiative to explore feasible and multiple methods of EBPH promotion. PMID:27597958

  4. Collaborative Research in Childhood Cancer Survivorship: The Current Landscape.

    Science.gov (United States)

    Bhatia, Smita; Armenian, Saro H; Armstrong, Gregory T; van Dulmen-den Broeder, Eline; Hawkins, Michael M; Kremer, Leontien C M; Kuehni, Claudia E; Olsen, Jørgen H; Robison, Leslie L; Hudson, Melissa M

    2015-09-20

    Survivors of childhood cancer carry a substantial burden of morbidity and are at increased risk for premature death. Furthermore, clear associations exist between specific therapeutic exposures and the risk for a variety of long-term complications. The entire landscape of health issues encountered for decades after successful completion of treatment is currently being explored in various collaborative research settings. These settings include large population-based or multi-institutional cohorts and single-institution studies. The ascertainment of outcomes has depended on self-reporting, linkage to registries, or clinical assessments. Survivorship research in the cooperative group setting, such as the Children's Oncology Group, has leveraged the clinical trials infrastructure to explore the molecular underpinnings of treatment-related adverse events, and to understand specific complications in the setting of randomized risk-reduction strategies. This review highlights the salient findings from these large collaborative initiatives, emphasizing the need for life-long follow-up of survivors of childhood cancer, and describing the development of several guidelines and efforts toward harmonization. Finally, the review reinforces the need to identify populations at highest risk, facilitating the development of risk prediction models that would allow for targeted interventions across the entire trajectory of survivorship.

  5. FES in Europe and Beyond: Current Translational Research

    Science.gov (United States)

    Coste, Christine Azevedo; Mayr, Winfried; Bijak, Manfred; Musarò, Antonio; Carraro, Ugo

    2016-01-01

    Capacity of adult neural and muscle tissues to respond to external Electrical Stimulation (ES) is the biological basis for the development and implementation of mobility impairment physiotherapy protocols and of related assistive technologies, e.g, Functional Electrical Stimulation (FES). All body tissues, however, respond to electrical stimulation and, indeed, the most successful application of FES is electrical stimulation of the heart to revert or limit effects of arrhythmias (Pace-makers and Defibrillators). Here, we list and discuss results of FES current research activities, in particular those presented at 2016 Meetings: the PaduaMuscleDays, the Italian Institute of Myology Meeting, the 20th International Functional Electrical Stimulation Society (IFESS) conference held in Montpellier and the Vienna Workshop on FES. Several papers were recently e-published in the European Journal of Translational Myology as reports of meeting presentations. All the events and publications clearly show that FES research in Europe and beyond is alive and promisses translation of results into clinical management of a very large population of persons with deficiencies. PMID:28078074

  6. FES in Europe and beyond: Current Translational Research

    Directory of Open Access Journals (Sweden)

    Christine Azevedo Coste

    2016-12-01

    Full Text Available Capacity of adult neural and muscle tissues to respond to external Electrical Stimulation (ES is the biological basis for the development and implementation of mobility impairment physiotherapy protocols and of related assistive technologies, e.g, Functional Electrical Stimulation (FES. All body tissues, however, respond to electrical stimulation and, indeed, the most successful application of FES is electrical stimulation of the heart to revert or limit effects of arrhythmias (Pace-makers and Defibrillators. Here, we list and discuss results of FES current research activities, in particular those presented at 2016 Meetings: the PaduaMuscleDays, the Italian Institute of Myology Meeting, the 20th International Functional Electrical Stimulation Society (IFESS conference held in Montpellier and the Vienna Workshop on FES. Several papers were recently e-published in the European Journal of Translational Myology as reports of meeting presentations. All the events and publications clearly show that FES research in Europe and beyond is alive and promisses translation of results into clinical management of a very large population of persons with deficiencies.

  7. State of multicultural neuropsychological assessment in children: current research issues.

    Science.gov (United States)

    Byrd, Desiree; Arentoft, Alyssa; Scheiner, Diane; Westerveld, Michael; Baron, Ida Sue

    2008-09-01

    Scientific attention to cultural considerations in child neuropsychological assessment has not developed parallel to the focus these issues have received in adult and elderly neuropsychological assessment. There are limited data on the presence, magnitude, etiology, and implications of culture-related differences in cognitive test performance among children. This preliminary report reviews the available empirical literature on the current state of multicultural neuropsychological assessment in children. The review identified articles by searching PubMed and PsycINFO databases, and the tables of contents of Developmental Neuropsychology and Child Neuropsychology from 2003-2008. Of the 1,834 abstracts reviewed, ten papers met inclusion criteria for the review. Five studies were completed in America; four of these compared performance between ethnic groups while the fifth examined neighborhood level poverty indicators exclusively within African-American children. Of the five international studies, all established local normative data and/or were exploratory investigations of neuropsychological functions in specific cultural groups, including Taiwanese infants, South African youth, and bilingual British children. Taken together, the results yield important clinical and research data that begin to inform many of the complex and fascinating mechanisms by which ethnic identity and culture impact cognitive development and the neuropsychological assessment of children. A critique of the existing literature and directions for future research are provided.

  8. Human behavioral assessments in current research of Parkinson's disease.

    Science.gov (United States)

    Asakawa, Tetsuya; Fang, Huan; Sugiyama, Kenji; Nozaki, Takao; Kobayashi, Susumu; Hong, Zhen; Suzuki, Katsuaki; Mori, Norio; Yang, Yilin; Hua, Fei; Ding, Guanghong; Wen, Guoqiang; Namba, Hiroki; Xia, Ying

    2016-09-01

    Parkinson's disease (PD) is traditionally classified as a movement disorder because patients mainly complain about motor symptoms. Recently, non-motor symptoms of PD have been recognized by clinicians and scientists as early signs of PD, and they are detrimental factors in the quality of life in advanced PD patients. It is crucial to comprehensively understand the essence of behavioral assessments, from the simplest measurement of certain symptoms to complex neuropsychological tasks. We have recently reviewed behavioral assessments in PD research with animal models (Asakawa et al., 2016). As a companion volume, this article will systematically review the behavioral assessments of motor and non-motor PD symptoms of human patients in current research. The major aims of this article are: (1) promoting a comparative understanding of various behavioral assessments in terms of the principle and measuring indexes; (2) addressing the major strengths and weaknesses of these behavioral assessments for a better selection of tasks/tests in order to avoid biased conclusions due to inappropriate assessments; and (3) presenting new concepts regarding the development of wearable devices and mobile internet in future assessments. In conclusion we emphasize the importance of improving the assessments for non-motor symptoms because of their complex and unique mechanisms in human PD brains.

  9. Institutional and legal arrangements in the Nile river basin: suggestions to improve the current situation toward adaptive integrated water resources management.

    Science.gov (United States)

    Abdalla, Khalid Mohamed El Hassan

    2008-01-01

    A comparative study was conducted in this work in order to investigate the current situation in the Nile river basin (NRB) regarding the institutional and legal arrangements needed to support the adaptive integrated water resources management (AIWRM) strategy. Two similar river basins were selected to achieve this comparison and to introduce suggestions to reform the current situation in the basin. Before that, the ideal situation is investigated to be as a yardstick for the desired situation. The study indicated that the necessary AIWRM criteria may include regulatory as well as implementation organizations that support shared-vision reaching with its all necessary features (cooperation, stakeholders' participation, subsidiarity, and information and knowledge exchange). Thus the main features of the desired situations regarding AIWRM in river basins are stakeholders' participation, learning-driven ability, quick response to risks and uncertainties, and finally a legal framework that could support these criteria. Although the AIWRM criteria seem to be satisfied in NRB, the basin lacks the necessary regulatory institutions as well as the legal framework. According to this, this study recommends to reform the current situation in NRB by creating regulator institutions (policy and decision making level) as well a legal framework to legitimate them.

  10. Public health services and systems research: current state of finance research.

    Science.gov (United States)

    Ingram, Richard C; Bernet, Patrick M; Costich, Julia F

    2012-11-01

    There is a growing recognition that the US public health system should strive for efficiency-that it should determine the optimal ways to utilize limited resources to improve and protect public health. The field of public health finance research is a critical part of efforts to understand the most efficient ways to use resources. This article discusses the current state of public health finance research through a review of public health finance literature, chronicles important lessons learned from public health finance research to date, discusses the challenges faced by those seeking to conduct financial research on the public health system, and discusses the role of public health finance research in relation to the broader endeavor of Public Health Services and Systems Research.

  11. Every scientist is a memory researcher: Suggestions for making research more memorable [v1; ref status: indexed, http://f1000r.es/500

    Directory of Open Access Journals (Sweden)

    Christopher R. Madan

    2015-01-01

    Full Text Available Independent of the actual results, some scientific articles are more memorable than others. As anyone who has written an article collaboratively knows, there are numerous ways a manuscript can be written to convey the same general ideas. To aid with this, many scientific writing books and editorials provide advice, often anecdotal, on how to make articles more memorable. Here I ground these suggestions with empirical support from memory research. Specifically, I suggest that researchers consider how to emphasize their work’s novelty, strive to describe their work using concrete, easy-to-understand terms, and use caution when attempting to evoke an emotional response in the reader. I also discuss considerations in title selections and conference presentations.

  12. Current practices and research updates on diabetes mellitus in canine

    Directory of Open Access Journals (Sweden)

    Pankaj Kumar

    2014-11-01

    Full Text Available Diabetes has evidence in ancient literatures, though recently is being considered as one amongst the most emerging disease condition in both human and companion animals. Diabetes mellitus is one of the common endocrinopathy of dog characterized by hyperglycemia, glycosuria and weight loss. Reports suggests high fraction of canine population suffer with diabetes world over. Studies in different veterinary hospitals of United States suggest increase in cases of canine diabetes and decrease in case fatality rate over time. Increase in cases of canine diabetes worldwide is attributed to awareness amongst pet owners, better veterinary health facilities, breed preferences by dog owners, increase dependence on commercial feeds, obesity, etc. Diabetes in most dogs is immune mediated and insulin dependent. Breed predisposition in canine is attributed to dog leukocyte antigen gene pool encoding form major histocompatibility complex-II molecules, however research is still underway. Diagnosis of diabetes still relies on blood sugar evaluation for screening of canine population, though many other diagnostic methods have shown promising benefits including measurement of fructosamine and glycated haemoglobin. Management of diabetes in dog is based on insulin therapy, diet modification and exercise. Use of oral anti-diabetics drugs in canine is limited though experimental studies have shown promising results. Alternative therapies have been explored, but only a few approaches have shown promise for clinical application.

  13. Ecosystem services – current challenges and opportunities for ecological research

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    Klaus eBirkhofer

    2015-01-01

    Full Text Available The concept of ecosystem services was originally developed to illustrate the benefits that natural ecosystems generate for society and to raise awareness for biodiversity and ecosystem conservation. In this article we identify major challenges and opportunities for ecologists involved in empirical or modeling ecosystem service research. The first challenge arises from the fact that the ecosystem service concept has not been generated in the context of managed systems. Ecologists need to identify the effect of anthropogenic interventions in order to propose practices to benefit service-providing organisms and associated services. The second challenge arises from the need to evaluate relationships between indicators of ecosystem services that are collected in ecological studies while accounting for uncertainties of ecological processes that underlie these services. We suggest basing the assessment of ecosystem services on the utilization of sets of indicators that cover aspects of service-providing units, ecosystem management and landscape modification. The third challenge arises from our limited understanding of the nature of relationships between services and a lack of a general statistical framework to address these links. To manage ecosystem service provisioning, ecologists need to establish whether services respond to a shared driver or if services are directly linked to each other. Finally, studies relating biodiversity to ecosystem services often focus on services at small spatial or short temporal scales, but research on the protection of services is often directed towards services providing benefits at large spatial scales. Ecological research needs to address a range of spatial and temporal scales to provide a multifaceted understanding of how nature promotes human well-being. Addressing these challenges in the future offers a unique opportunity for ecologists to act as promoters for the understanding about how to conserve benefits

  14. Current status of auditory aging and anti-aging research.

    Science.gov (United States)

    Ruan, Qingwei; Ma, Cheng; Zhang, Ruxin; Yu, Zhuowei

    2014-01-01

    The development of presbycusis, or age-related hearing loss, is determined by a combination of genetic and environmental factors. The auditory periphery exhibits a progressive bilateral, symmetrical reduction of auditory sensitivity to sound from high to low frequencies. The central auditory nervous system shows symptoms of decline in age-related cognitive abilities, including difficulties in speech discrimination and reduced central auditory processing, ultimately resulting in auditory perceptual abnormalities. The pathophysiological mechanisms of presbycusis include excitotoxicity, oxidative stress, inflammation, aging and oxidative stress-induced DNA damage that results in apoptosis in the auditory pathway. However, the originating signals that trigger these mechanisms remain unclear. For instance, it is still unknown whether insulin is involved in auditory aging. Auditory aging has preclinical lesions, which manifest as asymptomatic loss of periphery auditory nerves and changes in the plasticity of the central auditory nervous system. Currently, the diagnosis of preclinical, reversible lesions depends on the detection of auditory impairment by functional imaging, and the identification of physiological and molecular biological markers. However, despite recent improvements in the application of these markers, they remain under-utilized in clinical practice. The application of antisenescent approaches to the prevention of auditory aging has produced inconsistent results. Future research will focus on the identification of markers for the diagnosis of preclinical auditory aging and the development of effective interventions.

  15. Sleep disturbance due to noise: Current issues and future research

    Directory of Open Access Journals (Sweden)

    Ken Hume

    2010-01-01

    Full Text Available There is growing interest in carrying out further research to understand and reduce the impact of aircraft noise on airport neighborhood in anticipation of the projected substantial increase in global aviation. Soundscapes provide new analytical methods and a broader, more comprehensive appreciation of the aural environment, which may have a useful role in understanding noise-induced sleep disturbance and annoyance. Current noise metrics like Leq do not provide a common language to report noise environment to residents, which is a key obstacle to effective noise management and acceptance. Non-auditory effects complicate the production of consistent dose-response functions for aircraft noise affecting sleep and annoyance. There are various end-points that can be chosen to assess the degree of sleep disturbance, which has detracted from the clarity of results that has been communicated to wider audiences. The World Health Organization (WHO-Europe has produced Night Noise Guidelines for Europe, which act as a clear guide for airports and planners to work towards. Methodological inadequacies and the need for simpler techniques to record sleep will be considered with the exciting potential to greatly increase cost-effective field data acquisition, which is needed for large scale epidemiological studies

  16. Alcohol and NMDA Receptor: Current research and future direction

    Directory of Open Access Journals (Sweden)

    Raman eChandrasekar

    2013-05-01

    Full Text Available The brain is one of the major targets of alcohol actions. Most of the excitatory synaptic transmission in the central nervous system is mediated by NMDA receptors. However, one of the most devastating effects of alcohol leads to brain shrinkage, loss of nerve cells at specific regions through a mechanism involving excitotoxicity, oxidative stress. Earlier studies have indicated that chronic exposure to ethanol both in vivo and in vitro, increases NR1 and NR2B gene expression and their polypeptide levels. The effect of alcohol and molecular changes on the regulatory process, which modulates NMDAR functions including factors altering transcription, translation, post-translational modifications and protein expression, as well as those influencing their interactions with different regulatory proteins (downstream effectors are incessantly increasing at the cellular level. Further, I discuss the various genetically altered mice approaches that have been used to study NMDA receptor subunits and their functional implication. In a recent countable review, epigenetic dimension (i.e., histone modification-induced chromatin remodeling and DNA methylation, in the process of alcohol related neuroadapation is one of the key molecular mechanisms in alcohol mediated NMDAR alteration. Here, I provide a recount on what has already been achieved, current trends and how the future research/studies of the NMDA receptor might lead to even greater engagement with many possible new insights into the neurobiology and treatment of alcoholism.

  17. Alcohol and NMDA receptor: current research and future direction.

    Science.gov (United States)

    Chandrasekar, Raman

    2013-01-01

    The brain is one of the major targets of alcohol actions. Most of the excitatory synaptic transmission in the central nervous system is mediated by N-methyl-D-aspartate (NMDA) receptors. However, one of the most devastating effects of alcohol leads to brain shrinkage, loss of nerve cells at specific regions through a mechanism involving excitotoxicity, oxidative stress. Earlier studies have indicated that chronic exposure to ethanol both in vivo and in vitro, increases NR1 and NR2B gene expression and their polypeptide levels. The effect of alcohol and molecular changes on the regulatory process, which modulates NMDAR functions including factors altering transcription, translation, post-translational modifications, and protein expression, as well as those influencing their interactions with different regulatory proteins (downstream effectors) are incessantly increasing at the cellular level. Further, I discuss the various genetically altered mice approaches that have been used to study NMDA receptor subunits and their functional implication. In a recent countable review, epigenetic dimension (i.e., histone modification-induced chromatin remodeling and DNA methylation, in the process of alcohol related neuroadaptation) is one of the key molecular mechanisms in alcohol mediated NMDAR alteration. Here, I provide a recount on what has already been achieved, current trends and how the future research/studies of the NMDA receptor might lead to even greater engagement with many possible new insights into the neurobiology and treatment of alcoholism.

  18. Rethinking cancer: current challenges and opportunities in cancer research.

    Science.gov (United States)

    Cagan, Ross; Meyer, Pablo

    2017-04-01

    Cancer therapeutics currently have the lowest clinical trial success rate of all major diseases. Partly as a result of the paucity of successful anti-cancer drugs, cancer will soon be the leading cause of mortality in developed countries. As a disease embedded in the fundamentals of our biology, cancer presents difficult challenges that would benefit from uniting experts from a broad cross-section of related and unrelated fields. Combining extant approaches with novel ones could help in tackling this challenging health problem, enabling the development of therapeutics to stop disease progression and prolong patient lives. This goal provided the inspiration for a recent workshop titled 'Rethinking Cancer', which brought together a group of cancer scientists who work in the academic and pharmaceutical sectors of Europe, America and Asia. In this Editorial, we discuss the main themes emerging from the workshop, with the aim of providing a snapshot of key challenges faced by the cancer research community today. We also outline potential strategies for addressing some of these challenges, from understanding the basic evolution of cancer and improving its early detection to streamlining the thorny process of moving promising drug targets into clinical trials. © 2017. Published by The Company of Biologists Ltd.

  19. Rethinking cancer: current challenges and opportunities in cancer research

    Directory of Open Access Journals (Sweden)

    Ross Cagan

    2017-04-01

    Full Text Available Cancer therapeutics currently have the lowest clinical trial success rate of all major diseases. Partly as a result of the paucity of successful anti-cancer drugs, cancer will soon be the leading cause of mortality in developed countries. As a disease embedded in the fundamentals of our biology, cancer presents difficult challenges that would benefit from uniting experts from a broad cross-section of related and unrelated fields. Combining extant approaches with novel ones could help in tackling this challenging health problem, enabling the development of therapeutics to stop disease progression and prolong patient lives. This goal provided the inspiration for a recent workshop titled ‘Rethinking Cancer’, which brought together a group of cancer scientists who work in the academic and pharmaceutical sectors of Europe, America and Asia. In this Editorial, we discuss the main themes emerging from the workshop, with the aim of providing a snapshot of key challenges faced by the cancer research community today. We also outline potential strategies for addressing some of these challenges, from understanding the basic evolution of cancer and improving its early detection to streamlining the thorny process of moving promising drug targets into clinical trials.

  20. The microanatomy of the rectal salt gland of the Port Jackson Shark, Heterodontus portusjacksoni (Meyer) (Heterodontidae): suggestions for a counter-current exchange system.

    Science.gov (United States)

    Newbound, D R; O'Shea, J E

    2001-01-01

    A comprehensive anatomical study was undertaken to examine the rectal salt gland in the Port Jackson shark, Heterodontus portusjacksoni, a shark known to invade estuarine environments. The microstructure and vascular organisation of the rectal salt gland was investigated using histological observation and scanning electron microscopy of vascular corrosion casts. Cellular specialisation was observed in the lining of the central lumen of this gland. This may indicate that there is some modification of the principal product of the gland prior to its secretion. The rectal salt gland has a complex structure related to its function. Contrary to previous reports, the flow in secretory tubules is in the opposite direction to that of the capillaries and thus constitutes a counter-current arrangement. The similarity in the organisation of the counter-current and lobulate arrangement of salt-secreting glands through phylogenetically diverse organisms, such as sharks and birds, suggests that this arrangement is important in achieving efficient salt secretion. Copyright 2001 S. Karger AG, Basel

  1. The Evolution of Current Research Impact Metrics: From Bibliometrics to Altmetrics?

    Science.gov (United States)

    Butler, Joseph S; Kaye, I David; Sebastian, Arjun S; Wagner, Scott C; Morrissey, Patrick B; Schroeder, Gregory D; Kepler, Christopher K; Vaccaro, Alexander R

    2017-03-23

    The prestige of publication has been based on traditional citation metrics, most commonly journal impact factor. However, the Internet has radically changed the speed, flow, and sharing of medical information. Furthermore, the explosion of social media, along with development of popular professional and scientific websites and blogs, has led to the need for alternative metrics, known as altmetrics, to quantify the wider impact of research. We explore the evolution of current research impact metrics and examine the evolving role of altmetrics in measuring the wider impact of research. We suggest that altmetrics used in research evaluation should be part of an informed peer-review process such as traditional metrics. Moreover, results based on altmetrics must not lead to direct decision making about research, but instead, should be used to assist experts in making decisions. Finally, traditional and alternative metrics should complement, not replace, each other in the peer-review process.

  2. Science and cycling: current knowledge and future directions for research.

    Science.gov (United States)

    Atkinson, Greg; Davison, Richard; Jeukendrup, Asker; Passfield, Louis

    2003-09-01

    In this holistic review of cycling science, the objectives are: (1) to identify the various human and environmental factors that influence cycling power output and velocity; (2) to discuss, with the aid of a schematic model, the often complex interrelationships between these factors; and (3) to suggest future directions for research to help clarify how cycling performance can be optimized, given different race disciplines, environments and riders. Most successful cyclists, irrespective of the race discipline, have a high maximal aerobic power output measured from an incremental test, and an ability to work at relatively high power outputs for long periods. The relationship between these characteristics and inherent physiological factors such as muscle capilliarization and muscle fibre type is complicated by inter-individual differences in selecting cadence for different race conditions. More research is needed on high-class professional riders, since they probably represent the pinnacle of natural selection for, and physiological adaptation to, endurance exercise. Recent advances in mathematical modelling and bicycle-mounted strain gauges, which can measure power directly in races, are starting to help unravel the interrelationships between the various resistive forces on the bicycle (e.g. air and rolling resistance, gravity). Interventions on rider position to optimize aerodynamics should also consider the impact on power output of the rider. All-terrain bicycle (ATB) racing is a neglected discipline in terms of the characterization of power outputs in race conditions and the modelling of the effects of the different design of bicycle frame and components on the magnitude of resistive forces. A direct application of mathematical models of cycling velocity has been in identifying optimal pacing strategies for different race conditions. Such data should, nevertheless, be considered alongside physiological optimization of power output in a race. An even distribution

  3. Overview of recent and current research on the TCV tokamak

    Science.gov (United States)

    S. Codathe TCV Team

    2013-10-01

    Through a diverse research programme, the Tokamak à Configuration Variable (TCV) addresses physics issues and develops tools for ITER and for the longer term goals of nuclear fusion, relying especially on its extreme plasma shaping and electron cyclotron resonance heating (ECRH) launching flexibility and preparing for an ECRH and NBI power upgrade. Localized edge heating was unexpectedly found to decrease the period and relative energy loss of edge localized modes (ELMs). Successful ELM pacing has been demonstrated by following individual ELM detection with an ECRH power cut before turning the power back up to trigger the next ELM, the duration of the cut determining the ELM period. Negative triangularity was also seen to reduce the ELM energy release. H-mode studies have focused on the L-H threshold dependence on the main ion species and on the divertor leg length. Both L- and H-modes have been explored in the snowflake configuration with emphasis on edge measurements, revealing that the heat flux to the strike points on the secondary separatrix increases as the X-points approach each other, well before they coalesce. In L-mode, a systematic scan of the auxiliary power deposition profile, with no effect on confinement, has ruled it out as the cause of confinement degradation. An ECRH power absorption observer based on transmitted stray radiation was validated for eventual polarization control. A new profile control methodology was introduced, relying on real-time modelling to supplement diagnostic information; the RAPTOR current transport code in particular has been employed for joint control of the internal inductance and central temperature. An internal inductance controller using the ohmic transformer has also been demonstrated. Fundamental investigations of neoclassical tearing mode (NTM) seed island formation by sawtooth crashes and of NTM destabilization in the absence of a sawtooth trigger were carried out. Both stabilizing and destabilizing agents

  4. Current development of acupuncture research in Parkinson's disease.

    Science.gov (United States)

    Zeng, Bai-Yun; Salvage, Sarah; Jenner, Peter

    2013-01-01

    Parkinson's disease is an age-related progressive neurodegenerative disease. The etiology and pathogenetic mechanisms that cause PD are still not fully understood. The available treatments to PD are only symptomatic relief. Acupuncture is used to treat many medical conditions for 1000 years in China and has gained wider and increasing acceptance within both public and medical profession because it has been a very safe and well-tolerated treatment. In this chapter, we reviewed relevant laboratory findings regarding acupuncture mechanism on Parkinson's. We showed that acupuncture stimulation in Parkinson's models had generated valuable mechanistic insight of Parkinson's and showed that acupuncture treatment is in fact a neuroprotective therapy that increase the release of various neuroprotective agents such as brain-derived neurotrophic factor, glial cell line-derived neurotrophic factor, and cyclophilin A. In addition, acupuncture therapy slows cell death process and attenuates oxidative stress to dopaminergic neurons in the substantia nigra. Further, acupuncture therapy modulates neuronal activity of the basal ganglia output structures. These results suggest that early application of acupuncture therapy to Parkinson's patients may be helpful for the best efficacy of acupuncture treatment. It is hopeful that translation of achievement in acupuncture research in Parkinson's models will maximize the potentials of acupuncture treatment.

  5. Asthma in the Elderly: Current Understanding and Future Research Needs

    Science.gov (United States)

    Hanania, Nicola A.; King, Monroe J.; Braman, Sidney S.; Saltoun, Carol; Wise, Robert A.; Enright, Paul; Falsey, Ann A; Mathur, Sameer K.; Ramsdell, Joe W.; Rogers, Linda; Stempel, David A.; Lima, John J.; Fish, James E.; Wilson, Sandra R.; Boyd, Cynthia; Patel, Kushang V.; Irvin, Charles G.; Yawn, Barbara P.; Halm, Ethan A; Wasserman, Stephen I.; Sands, Mark F.; Ershler, William B.; Ledford, Dennis K.

    2011-01-01

    Asthma in the elderly (AIE) is under diagnosed and under treated and there is a paucity of knowledge. The National Institute on Aging convened this workshop to identify what is known, what gaps in knowledge remain and suggest research directions needed to improve the understanding and care of AIE. Asthma presenting at an advanced age often has similar clinical and physiologic consequences as seen with younger individuals but co-morbid illnesses and the psychosocial effects of aging may affect the diagnosis, clinical presentation and care of asthma in this population. At least two phenotypes exist among elderly asthma; those with long-standing asthma have more severe airflow limitation and less complete reversibility than those with late-onset asthma. Many challenges exist in the recognition and treatment of asthma in the elderly. Furthermore, the pathophysiological mechanisms of AIE are likely to be different from those seen in young asthmatics and these differences may influence the clinical course and outcomes of asthma in this population. PMID:21872730

  6. CURRENT APPROACHES FOR RESEARCH OF MULTIPLE SCLEROSIS BIOMARKERS

    Directory of Open Access Journals (Sweden)

    Kolyada T.I

    2016-12-01

    Full Text Available Current data concerning features of multiple sclerosis (MS etiology, pathogenesis, clinical course and treatment of disease indicate the necessity of personalized approach to the management of MS patients. These features are the variety of possible etiological factors and mechanisms that trigger the development of MS, different courses of disease, and significant differences in treatment efficiency. Phenotypic and pathogenetic heterogeneity of MS requires, on the one hand, the stratification of patients into groups with different treatment depending on a number of criteria including genetic characteristics, disease course, stage of the pathological process, and forms of the disease. On the other hand, it requires the use of modern methods for assessment of individual risk of developing MS, its early diagnosis, evaluation and prognosis of the disease course and the treatment efficiency. This approach is based on the identification and determination of biomarkers of MS including the use of systems biology technology platforms such as genomics, proteomics, metabolomics and bioinformatics. Research and practical use of biomarkers of MS in clinical and laboratory practice requires the use of a wide range of modern medical and biological, mathematical and physicochemical methods. The group of "classical" methods used to study MS biomarkers includes physicochemical and immunological methods aimed at the selection and identification of single molecular biomarkers, as well as methods of molecular genetic analysis. This group of methods includes ELISA, western blotting, isoelectric focusing, immunohistochemical methods, flow cytometry, spectrophotometric and nephelometric methods. These techniques make it possible to carry out both qualitative and quantitative assay of molecular biomarkers. The group of "classical methods" can also include methods based on polymerase chain reaction (including multiplex and allele-specific PCR and genome sequencing

  7. Attachment among older adults: current issues and directions for future research.

    Science.gov (United States)

    Bradley, J M; Cafferty, T P

    2001-09-01

    Although John Bowlby conceptualized attachment theory as applicable across the life span, researchers have been relatively slow to examine attachment phenomena specifically among older adults. The present article reviews the extant research applying attachment theory to older populations; preliminary findings suggest that attachment issues hold particular relevance for older adults, given the increased potential for separation, loss and vulnerability associated with aging. Although many of the studies reviewed are somewhat limited methodologically, the overall pattern of results suggests that attachment patterns are associated with a variety of outcomes in later life (such as adaptation to chronic illness and caregiver burden among family members, reactions to the death of a loved one, and general well-being) in a theoretically consistent manner. The implications of and questions raised by current findings are reviewed, and directions for future research are discussed.

  8. Current status of NADPH oxidase research in cardiovascular pharmacology

    Directory of Open Access Journals (Sweden)

    Rodiño-Janeiro BK

    2013-07-01

    Full Text Available Bruno K Rodiño-Janeiro,1,2 Beatriz Paradela-Dobarro,1 María Isabel Castiñeiras-Landeira,1 Sergio Raposeiras-Roubín,1,3 José R González-Juanatey,1,3,4 Ezequiel Álvarez1,4 1Health Research Institute of Santiago de Compostela, Santiago de Compostela, Spain; 2European Molecular Biology Laboratory, Grenoble, France; 3Cardiology Department, University Clinic Hospital of Santiago de Compostela, Santiago de Compostela, Spain; 4Medicine Department, University of Santiago de Compostela, Santiago de Compostela, Spain Abstract: The implications of reactive oxygen species in cardiovascular disease have been known for some decades. Rationally, therapeutic antioxidant strategies combating oxidative stress have been developed, but the results of clinical trials have not been as good as expected. Therefore, to move forward in the design of new therapeutic strategies for cardiovascular disease based on prevention of production of reactive oxygen species, steps must be taken on two fronts, ie, comprehension of reduction-oxidation signaling pathways and the pathophysiologic roles of reactive oxygen species, and development of new, less toxic, and more selective nicotinamide adenine dinucleotide phosphate (NADPH oxidase inhibitors, to clarify both the role of each NADPH oxidase isoform and their utility in clinical practice. In this review, we analyze the value of NADPH oxidase as a therapeutic target for cardiovascular disease and the old and new pharmacologic agents or strategies to prevent NADPH oxidase activity. Some inhibitors and different direct or indirect approaches are available. Regarding direct NADPH oxidase inhibition, the specificity of NADPH oxidase is the focus of current investigations, whereas the chemical structure-activity relationship studies of known inhibitors have provided pharmacophore models with which to search for new molecules. From a general point of view, small-molecule inhibitors are preferred because of their hydrosolubility

  9. Current Research and Classroom Practice: Toward More Inclusive Approaches to Literacy Development in Schools

    Directory of Open Access Journals (Sweden)

    David Booth

    2009-07-01

    Full Text Available This paper offers an exploration of current research and related practice in boys’ literacy development, interprets key findings in the literature, and further explores some of the complex dilemmas and debates related to the ‘gender gap’ – i.e., differences between the achievement of boys and girls in this area. In conclusion, the authors suggest that governments, policy-makers, administrators, teachers and parents all need to closely examine and consider available research-based strategies and classroom interventions that can effectively support both boys and girls in their literacy development. 

  10. Summary of current research on Central Asian vortex

    Directory of Open Access Journals (Sweden)

    Lian-Mei YANG

    2017-03-01

    Full Text Available The Central Asian vortex (CAV is an important synoptic-scale system that causes rainstorms, short-term heavy precipitation, hail, and sustained low temperatures in Xinjiang. This paper summarizes the current research conducted on the CAV since the 1960s. The objective definition of the CAV has been revised and a deep and shallow CAV classification proposed. Two high-frequency areas of deep CAV activity are the Kazakhstan hills (Sayan mountains and the eastern area of the Aral Sea (Tashkent; events mostly occur in summer and 40% cause strong rainfall. In addition, two high-frequency activity areas of the shallow CAV are located in the west and south of the Pamirs Plateau and mostly occur in spring; 23.2% of occurrences cause strong rainfall. The western and eastern water vapor transport relates to westerlies and a strong low-level easterly jet stream (LLEJ extending from Gansu to Xinjiang, respectively, and water vapor over the Tibetan Plateau transports even more northwards and enters Xinjiang. The deep CAV has an obvious cold core structure down to 300 hPa. The conversion terms from eddy available potential energy (AE to eddy kinetic energy (KE and eddy kinetic energy inflow (BKE from the open atmospheric region boundaries are the main sources of KE which cause rapid development of the CAV. The anomalous anti-cyclone center over the northeast Atlantic is the fountain of Rossby wave energy dispersion; Rossby waves propagate from the northeast Atlantic to eastern Europe (Urals (EEU, and then continuously propagate to Central Asia causing development of the CAV. The CAV requires further study to characterize the meso-scale system structure and evolution characteristics. In addition, physical modeling of the severe convective weather occurring under the CAV is required to determine the critical impacts of this severe convective weather and enable forecasting and early-warning indexes.

  11. Long-Term Engagement in Authentic Research with NASA (LEARN): Innovative Practices Suggested By a New Model for Teacher Research Experiences

    Science.gov (United States)

    Pippin, M. R.; Joseph, J. D.; Yang, M. M.; Omar, A. H.; Crecelius, S.; Harte, T.; Lewis, P. M., Jr.; Taylor, J.; Bujosa, R.; Moulton, C.; Haggard, C. S.; Hyater-Adams, S.; Kollmeyer, R.; Weisman, A.

    2014-12-01

    NASA's LEARN Project is an innovative program that provides long-term immersion in the practice of atmospheric science for middle and high school in-service teachers. Working alongside NASA scientists and using authentic NASA Science Mission Directorate research data, teachers develop individual research topics of interest during two weeks in the summer while on-site at NASA Langley. With continued, intensive mentoring by NASA scientists, the teachers further develop their research throughout the academic year through virtual group meetings and data team meetings mirroring scientific collaborations. At the end of the first year, LEARN teachers present scientific posters. The LEARN experience has had such an impact that multiple teachers from the first two cohorts have elected to continue their research. The LEARN project evaluation has provided insights into particularly effective elements of this new approach. Findings indicate that teachers' perceptions of the scientific enterprise have changed, and that LEARN provided substantial resources to help them take real-world research to their students. This presentation will focus on key factors from LEARN's implementation that inform best practices for the incorporation of authentic scientific research into teacher professional development experiences. We suggest that these factors should be considered in the development of other such experiences, including: (1) The involvement of a single scientist as both the project leader/manager and the project scientist, to ensure that the project can meet teachers' needs. (2) An emphasis on framing and approaching scientific research questions, so that teachers can learn to evaluate the feasibility of studies based on scope, scale, and availability of data. (3) Long term, ongoing relationships where teachers and scientists work as collaborators, beyond the workshop "mold." (4) A focus on meeting the needs of individual teachers, whether their needs relate to elements of

  12. International Inventory of Current Mexico-Related Research. Volume 4.

    Science.gov (United States)

    Montoya, Ricardo Anzaldua, Ed.; And Others

    The fourth annual research inventory describes 728 Mexican-related research projects being conducted in 1984 or to begin in 1985 in 14 countries. Data come from questionnaires sent during 1984 to more than 1,800 individual researchers and 650 institutions around the world. Each project description provides names and addresses of principal and…

  13. Current developments in environmental psychology : topics and researchers

    NARCIS (Netherlands)

    van der Werff, Ellen; Perlaviciute, Goda; Muinos, Gabriel

    2016-01-01

    The aim of this special issue is to bring the work of early-career researchers in environmental psychology to the spotlight. These young researchers come from different countries and cultures, have their own theoretical approaches and employ different research methods to increase knowledge on the re

  14. Cancer Treatment-Related Cardiotoxicity: Understanding the Current State of Knowledge and Developing Future Research Priorities

    Science.gov (United States)

    Cancer Treatment-Related Cardiotoxicity: Understanding the Current State of Knowledge and Developing Future Research Priorities, a 2013 workshop sponsored by the Epidemiology and Genomics Research Program.

  15. Simulations suggest that social and natural sciences differ in their research strategies adapted to work for different knowledge landscapes

    CERN Document Server

    Jaffe, Klaus

    2014-01-01

    Do different field of knowledge require different research strategies? A numerical model exploring different virtual knowledge landscapes, revealed different optimal search strategies. Trend following is maximized when the popularity of new discoveries determine the number of individuals researching it. This strategy works best when many researchers explore few large areas of knowledge. In contrast, individuals or small groups of researchers are better in discovering small bits of information in dispersed knowledge landscapes. The best technique for all situations simulated, is to adjust the number of researchers needed to explore a knowledge cluster according to the opportunities and the level of crowding in that cluster. Bibliometric data of scientific publications showed a continuous bipolar distribution of these strategies, ranging from natural sciences, with highly cited publications in journals containing a large number of articles, to the social sciences, with rarely cited publications in journals cont...

  16. Bibliometric Analysis of Current Web Survey Research in China

    Institute of Scientific and Technical Information of China (English)

    ZHANG Qian; SHAO Peiji; FANG Jiaming

    2008-01-01

    In recent years, with the advancement of information technology and its application in survey activities, web surveys have not only greatly developed, but have also encountered many problems in China. An analysis of domestic research is important for better understanding of web surveys, to guide further research and application. This paper gives a bibliometric analysis of 120 domestic articles on web surveys from 1998 to 2006, on publication growth, author and organization distribution, journal distribution, and research subjects. Research on web surveys in China should make progress comparable with research abroad in comparative studies, specific studies, and technical application studies.

  17. The value of value of information: best informing research design and prioritization using current methods.

    Science.gov (United States)

    Eckermann, Simon; Karnon, Jon; Willan, Andrew R

    2010-01-01

    partial EVPI may have potential value in refining overall research design. However, Occam's razor must be seriously considered in application of these VOI methods, given their increased complexity and current limitations in informing decision making, with restriction to EVPI rather than EVSI and not allowing for important decision-making contexts. Initial use of CLT methods to focus these more complex partial VOI methods towards where they may be useful in refining optimal overall trial design is suggested. Integrating CLT methods with such partial VOI methods to allow estimation of partial EVSI is suggested in future research to add value to the current VOI toolkit.

  18. Research and design of a novel current mode charge pump

    Science.gov (United States)

    Xianrui, Li; Xinquan, Lai; Yushan, Li; Qiang, Ye

    2009-10-01

    To meet the demands for a number of LEDs, a novel charge pump circuit with current mode control is proposed. Regulation is achieved by operating the current mirrors and the output current of the operational transconductance amplifier. In the steady state, the input current from power voltage retains constant, so reducing the noise induced on the input voltage source and improving the output voltage ripple. The charge pump small-signal model is used to describe the device's dynamic behavior and stability. Analytical predictions were verified by Hspice simulation and testing. Load driving is up to 800 mA with a power voltage of 3.6 V, and the output voltage ripple is less than 45 mV. The output response time is less than 8 μs, and the load current jumps from 400 to 800 mA.

  19. Research and design of a novel current mode charge pump

    Energy Technology Data Exchange (ETDEWEB)

    Li Xianrui; Lai Xinquan; Li Yushan; Ye Qiang, E-mail: lixianrui4213@126.co [Research Institute of Design Circuit, Xidian University, Xi' an 710071 (China)

    2009-10-15

    To meet the demands for a number of LEDs, a novel charge pump circuit with current mode control is proposed. Regulation is achieved by operating the current mirrors and the output current of the operational transconductance amplifier. In the steady state, the input current from power voltage retains constant, so reducing the noise induced on the input voltage source and improving the output voltage ripple. The charge pump small-signal model is used to describe the device's dynamic behavior and stability. Analytical predictions were verified by Hspice simulation and testing. Load driving is up to 800 mA with a power voltage of 3.6 V, and the output voltage ripple is less than 45 mV. The output response time is less than 8 {mu}s, and the load current jumps from 400 to 800 mA.

  20. Research and design of a novel current mode charge pump

    Institute of Scientific and Technical Information of China (English)

    Li Xianrui; Lai Xinquan; Li Yushan; Ye Qiang

    2009-01-01

    To meet the demands for a number of LEDs, a novel charge pump circuit with current mode control is proposed. Regulation is achieved by operating the current mirrors and the output current of the operational transcon ductance amplifier. In the steady state, the input current from power voltage retains constant, so reducing the noise induced on the input voltage source and improving the output voltage ripple. The charge pump small-signal model is used to describe the device's dynamic behavior and stability. Analytical predictions were verified by Hspice sim ulation and testing. Load driving is up to 800 mA with a power voltage of 3.6 V, and the output voltage ripple is less than 45 mV. The output response time is less than 8 μs, and the load current jumps from 400 to 800 mA.

  1. Current status of research on biophysical effects of ultrasound.

    Science.gov (United States)

    Barnett, S B; ter Haar, G R; Ziskin, M C; Nyborg, W L; Maeda, K; Bang, J

    1994-01-01

    This overview of bioeffects of ultrasound presents some key aspects of selected papers dealing with biophysical end-points. Its purpose is to establish a basis for exposure and dosimetric standards for medical ultrasonic equipment. It is intended to provide essential background resource material for the medical/scientific community, and more specifically for scientific working groups. This document was prepared by members of the Safety Committee of the World Federation for Ultrasound in Medicine and Biology. It was produced as a resource document in response to a request for information by Working Group 12 (Ultrasound exposure parameters) of the International Electrotechnical Commission Technical Committee 87, Ultrasonics. IEC TC 87, WG12 is the working group responsible for generating international standards for the classification of equipment by its acoustic fields based on safety thresholds. Our paper is intended to update and supplement information on the thermal mechanism provided in the publication, "WFUMB Symposium on Safety and Standardisation in Medical Ultrasound: Issues and Recommendations Regarding Thermal Mechanisms for Biological Effects of Ultrasound" (WFUMB 1992). It also provides an overview of trends in research into nonthermal mechanisms as a preliminary to the next WFUMB Symposium on Safety of Medical Ultrasound when this subject will be examined in detail by a select group of international experts. The WFUMB-sponsored workshop will take place in Utsunomiya, Japan during 11-15th July, 1994. The purpose of the meeting is to evaluate the scientific literature and to formulate internationally accepted recommendations on the safe use of diagnostic ultrasound that may be endorsed as official policy of the WFUMB. It should be noted that the current publication is not intended for review or endorsement as an official WFUMB document. It is produced as a scientific paper by individuals who are members of the WFUMB Safety Committee, and it therefore

  2. Analysis of educational research at a medical faculty in Germany and suggestions for strategic development - a case study.

    Science.gov (United States)

    Prediger, Sarah; Harendza, Sigrid

    2016-01-01

    Background: Evidence-based medical education is playing an increasingly important role in the choice of didactic methods and the development of medical curricula and assessments. In Germany, a growing number of educational research projects has accompanied an ongoing change in the medical education process. The aim of this project was to assess medical education research activities at one medical faculty to develop procedural recommendations for the support and development of best evidence medical education. Methods: Using a newly developed online questionnaire, the 65 institutes and departments of the medical faculty of Hamburg University at Hamburg University Medical-Center (UKE) were asked to report their medical education research and service projects, medical education publications, medical education theses, financial support for educational projects, and supportive structures that they would consider helpful in the future. The data were grouped, and a SWOT analysis was performed. Results: In total, 60 scientists who were involved in 112 medical education research publications between 1998 and 2014 were identified at the UKE. Twenty-five of them had published at least one manuscript as first or last author. Thirty-three UKE institutions were involved in educational service or research projects at the time of the study, and 75.8% of them received internal or external funding. Regular educational research meetings and the acquisition of co-operation partners were mentioned most frequently as beneficial supportive structures for the future. Conclusion: An analysis to define the status quo of medical education research at a medical faculty seems to be a helpful first step for the development of a strategy and structure to further support researchers in medical education.

  3. Mandates, needs, equitable resources, and current research in English language teacher education: The case of Turkey

    Directory of Open Access Journals (Sweden)

    Saban Cepik

    2014-02-01

    Full Text Available Improving the quality of English language teacher education (ELTE programs has become a major point of consideration; however, such programmatic evaluations are markedly rare. This study utilizes both numeric and interpretive qualitative data in a blended research design. The study addresses, vis-à-vis current research in related fields: What is the current situation of the Turkish ELTE programs in terms of curriculum strength and faculty resources? How do the program directors and teacher candidates envision the situation of their programs in terms of curriculum strength and faculty resources? Data included 45 ELTE curricula, interviews with 24 program directors and pre-service teachers, documents, and test scores. Findings revealed several significant associations between school type (public/private and rank (low/high and the number of faculty with expertise in critical areas in the field. Qualitative critical evaluations suggest both perceptual matches and mismatches between program directors and teacher candidates regarding programmatic strengths and weaknesses.

  4. The current status of nuclear research reactor in Thailand

    Energy Technology Data Exchange (ETDEWEB)

    Sittichai, C.; Kanyukt, R.; Pongpat, P. [Office of Atomic Energy for Peace, Bangkok (Thailand)

    1998-10-01

    Since 1962, the Thai Research Reactor has been serving for various kinds of activities i.e. the production of radioisotopes for medical uses and research and development on nuclear science and technology, for more than three decades. The existing reactor site should be abandoned and relocated to the new suitable site, according to Thai cabinet`s resolution on the 27 December 1989. The decommissioning project for the present reactor as well as the establishment of new nuclear research center were planned. This paper discussed the OAEP concept for the decommissioning programme and the general description of the new research reactor and some related information were also reported. (author)

  5. Promotion of sexual education by nurses in Macau-current state and suggestions%澳门护士推行性教育现状与建议

    Institute of Scientific and Technical Information of China (English)

    余惠莺; 黄翠萍; 李雪屏

    2015-01-01

    In the recent decade,the Macau Government,community associations and schools have been making concerted efforts to initiate sexual education.Nursing professionals in Macau,being the largest population of frontline health care providers,play an indispensable role in promoting adolescents’sexual health.Nurses in Macau have been promoting sexual education in three aspects,namely (1)nursing students initiate sexual education pro-jects under supervisors’guidance,(2)nurses in schools promote sexual health to school students on a regular ba-sis,(3)apart from launching relevant promotion activities in communities,professional associations of nurses also provide consultative services on physiological and sexual knowledge to adolescents in collaboration with the Govern-ment.Moreover,by organizing academic symposia,the associations initiate discussions on relevant topics and offer suggestions to the Government to consummate the relevant policies.In terms of the role in sexual health promotion, in addition to offering disease assessment,examination and nursing care,and arranging sexual health promotion ac-tivities in communities and schools,nursing professionals are suggested to also take up the responsibilities from the leadership aspect by monitoring and enhancing the quality and safety of the relevant services.Furthermore,from the research aspect,nursing professionals may initiate relevant researches and capitalize on the research findings to ele-vate service quality.%近十年,澳门政府、民间机构、学校共同合作开展性教育,澳门的护理人员作为前线健康服务提供者中最大的群体,在青少年的性健康上担当着不可或缺的角色。澳门护士从三个层次推行性教育,一是澳门护士学生在导师带领下开展性教育项目;二是澳门学校护士在学校定期推广性健康,对学生进行性教育;三是护士专业团体除到小区进行有关推广外,还会与政府合作为青少年提供生

  6. Urban tourism research : Recent progress and current paradoxes

    NARCIS (Netherlands)

    Ashworth, Gregory; Page, Stephen J.

    Urban tourism has remained a consistent theme in the expansion of tourism research since the 1980s and several seminal papers (e.g. Ashworth, 1989, 2003) have reviewed the state of research and its progress towards a greater recognition. This Progress in Tourism Management review article moves our

  7. The Research on School Marketing: Current Issues and Future Directions

    Science.gov (United States)

    Oplatka, Izhar; Hemsley-Brown, Jane

    2004-01-01

    This review provides a synthesis of the scholarship that has sought to expand the understanding of educational marketing practice in schools. The following research questions guided this review. What are the common themes and characteristics that emerge from research about marketing in schools? What remains underdeveloped in the characterization…

  8. Postgraduate Research Supervision: A Critical Review of Current Practice

    Science.gov (United States)

    McCallin, Antoinette; Nayar, Shoba

    2012-01-01

    Changes in the funding and delivery of research programmes at the university level have, in recent years, resulted in significant changes to research supervision. This paper critically reviews key influences effecting postgraduate supervision. Analysis draws on literature spanning 2000-2010 to determine the appropriateness of traditional models of…

  9. Urban tourism research : Recent progress and current paradoxes

    NARCIS (Netherlands)

    Ashworth, Gregory; Page, Stephen J.

    2011-01-01

    Urban tourism has remained a consistent theme in the expansion of tourism research since the 1980s and several seminal papers (e.g. Ashworth, 1989, 2003) have reviewed the state of research and its progress towards a greater recognition. This Progress in Tourism Management review article moves our u

  10. Human memory research: Current hypotheses and new perspectives

    Directory of Open Access Journals (Sweden)

    Antônio Jaeger

    Full Text Available Abstract Research on human memory has increased significantly in the last few decades. Inconsistencies and controversies inherent to such research, however, are rarely articulated on published reports. The goal of the present article is to present and discuss a series of open questions related to major topics on human memory research that can be addressed by future research. The topics covered here are visual working memory, recognition memory, emotion and memory interaction, and methodological issues of false memories studies. Overall, the present work reveals a series of open questions and alternative analysis which could be useful for the process of hypothesis generation, and consequently for the design and implementation of future research on human memory.

  11. Review of current research on hydrocarbon production by plants

    Energy Technology Data Exchange (ETDEWEB)

    Benedict, H. M.; Inman, B.

    1979-01-01

    This review assesses the status of research and development in the area of plants that produce hydrocarbons as a possible replacement for traditional fossil fuels. The information is meant to be used as a basis for determining the scope of a possible R and D program by DOE/FFB. Except in the case of guayule (Parthenium argentatum Gray), research on hydrocarbon species generally has not advanced beyond preliminary screening, extraction, and growth studies. Virtually no field studies have been initiated; hydrocarbon component extraction, separation, identification, and characterization have been only timidly approached; the biochemistry of hydrocarbon formation remains virtually untouched; and potential market analysis has been based on insufficient data. Research interest is increasing in this area, however. Industrial interest understandably centers about guayule prospects and is supplemented by NSF and DOE research funds. Additional support for other research topics has been supplied by DOE and USDA and by certain university systems. Due to the infant state of technology in this area of energy research, it is not possible to predict or satisfactorily assess at this time the potential contribution that plant hydrocarbons might make toward decreasing the nation's dependence upon petroleum. However, the general impression received from experts interviewed during this review was that the major thrust of research should be directed toward the manufacture of petrochemical substitutes rather than fuel production.

  12. Review of current research on hydrocarbon production by plants

    Energy Technology Data Exchange (ETDEWEB)

    Benedict, H. M.; Inman, B.

    1979-01-01

    This review assesses the status of research and development in the area of plants that produce hydrocarbons as a possible replacement for traditional fossil fuels. The information is meant to be used as a basis for determining the scope of a possible R and D program by DOE/FFB. Except in the case of guayule (Parthenium argentatum Gray), research on hydrocarbon species generally has not advanced beyond preliminary screening, extraction, and growth studies. Virtually no field studies have been initiated; hydrocarbon component extraction, separation, identification, and characterization have been only timidly approached; the biochemistry of hydrocarbon formation remains virtually untouched; and potential market analysis has been based on insufficient data. Research interest is increasing in this area, however. Industrial interest understandably centers about guayule prospects and is supplemented by NSF and DOE research funds. Additional support for other research topics has been supplied by DOE and USDA and by certain university systems. Due to the infant state of technology in this area of energy research, it is not possible to predict or satisfactorily assess at this time the potential contribution that plant hydrocarbons might make toward decreasing the nation's dependence upon petroleum. However, the general impression received from experts interviewed during this review was that the major thrust of research should be directed toward the manufacture of petrochemical substitutes rather than fuel production.

  13. Traditional Japanese Kampo Medicine: Clinical Research between Modernity and Traditional Medicine—The State of Research and Methodological Suggestions for the Future

    Directory of Open Access Journals (Sweden)

    Kenji Watanabe

    2011-01-01

    Full Text Available The Japanese traditional herbal medicine, Kampo, has gradually reemerged and 148 different formulations (mainly herbal extracts can be prescribed within the national health insurance system. The objective of this article is to introduce Kampo and to present information from previous clinical studies that tested Kampo formulae. In addition, suggestions on the design of future research will be stated. The literature search was based on a summary, up until January 2009, by the Japanese Society of Oriental Medicine and included only those trials which were also available in either Pubmed or ICHUSHI (Japan Medical Abstracts Society. We included 135 studies, half of these studies (n=68 used a standard control and 28 a placebo control. Thirty-seven trials were published in English [all randomized controlled trials (RCTs] and the remaining articles were in Japanese only. The sample size for most studies was small (two-third of the studies included less than 100 patients and the overall methodological quality appeared to be low. None of the studies used Kampo diagnosis as the basis for the treatment. In order to evaluate Kampo as a whole treatment system, certain aspects should be taken into account while designing studies. RCTs are the appropriate study design to test efficacy or effectiveness; however, within the trial the treatment could be individualized according to the Kampo diagnosis. Kampo is a complex and individualized treatment with a long tradition, and it would be appropriate for further research on Kampo medicine to take this into account.

  14. [Current situation and development trend of Chinese medicine information research].

    Science.gov (United States)

    Dong, Yan; Cui, Meng

    2013-04-01

    Literature resource service was the main service that Chinese medicine (CM) information offered. But in recent years users have started to request the health information knowledge service. The CM information researches and application service mainly included: (1) the need of strength studies on theory, application of technology, information retrieval, and information standard development; (2) Information studies need to support clinical decision making, new drug research; (3) Quick response based on the network monitoring and support to emergency countermeasures. CM information researches have the following treads: (1) developing the theory system structure of CM information; (2) studying the methodology system of CM information; (3) knowledge discovery and knowledge innovation.

  15. Current research trends in mountain biodiversity in NW Europe

    Directory of Open Access Journals (Sweden)

    Väisänen, Risto A.

    1998-12-01

    Full Text Available Focusing on four themes in relation to biodiversity (vegetation science, keystone grazers, long-term studies and protected areas, a synthesis of current research in the mountain areas of Fennoscandia, Iceland and Scotland is presented. Recent relevant advances in vegetation science include classifications of mountain habitats which together with species distribution maps offer new possibilities for analysis. Generalisations emerging from comparisons of the ecology and ecophysiology of plants between different mountain areas are greatly needed. Further studies on the ecological impacts of keystone grazers are urgently required because of the alarming rate of degradation of mountain habitats. The topics highlighted from northern Fennoscandia include (i the effect of overgrazing by reindeer on the cover of foliose lichens and on the regeneration of mountain birch, (ii the ecological interactions between the autumnal moth and mountain birch, and (Hi the effect of rodents on vegetation. Long-term studies of slow processes to capture rare but important events are needed to better understand the functioning of mountain ecosystems. Examples of such studies are presented for (i the moss Racomitrium lanuginosum as an indicator of airborne nitrogen pollution, (ii research based on cyclic oscillations of vole numbers, and (Hi the application of breeding birds in environmental assessment. The conservation of appropriate areas is important for mountain biodiversity. Mountain habitats have been protected extensively in northern Europe. The evaluation of how representative the existing areas are and how to use them for research need international co-ordination.

    [fr] On présente une synthèse de la recherche actuelle dans les régions de montagne de la Scandinavie, l'Islande et l'Ecosse, centrée sur quatre sujets autour de la biodiversité (science de la végétation, herbivores principaux, études à long terme et zones protégées. Les r

  16. Relationship Education Research: Current Status and Future Directions

    Science.gov (United States)

    Markman, Howard J.; Rhoades, Galena K.

    2011-01-01

    The overarching aim of this paper is to review research on relationship education programs and approaches that have been published or accepted for publication since the last review article in 2002. This paper provides a critical overview of the relationship education field and sets an agenda for research and practice for the next decade. A theme weaved throughout the paper are the ways in which relationship education is similar and different from couples therapy and we conclude that there can be a synergistic, healthy marriage between the two. We then provide recommendations for future directions for research in the relationship education field. Finally, the co-authors comment on our experiences in both the relationship education field and couples therapy field as both researchers and interventionists. PMID:22283386

  17. Research on cancer diagnosis in Malaysia: current status.

    Science.gov (United States)

    Looi, L M; Zubaidah, Z; Cheah, P L; Cheong, S K; Gudum, H R; Iekhsan, O; Ikram, S I; Jamal, R; Mak, J W; Othman, N H; Puteri, J N; Rosline, H; Sabariah, A R; Seow, H F; Sharifah, N A

    2004-06-01

    Cancer is a major morbidity and mortality concern in Malaysia. Based on National Cancer Registry data, the Malaysian population is estimated to bear a cancer burden of about 40,000 new cases per year, and a cumulative lifetime risk of about 1:4. Cancer research in Malaysia has to consider needs relevant to our population, and resources constraints. Hence, funding bodies prioritise cancers of high prevalence, unique to our community and posing specific clinical problems. Cancer diagnosis is crucial to cancer management. While cancer diagnosis research largely aims at improvements in diagnostic information towards more appropriate therapy, it also impacts upon policy development and other areas of cancer management. The scope of cancer diagnosis upon which this paper is based, and their possible impact on other R&D areas, has been broadly categorized into: (1) identification of aetiological agents and their linkages to the development of precancer and cancer (impact on policy development, cancer prevention and treatment), (2) cancer biology and pathogenesis (impact on cancer prevention, treatment strategies and product development), (3) improvements in accuracy, sensitivity and specificity in cancer detection, monitoring and classification (impact on technology development) and (4) prognostic and predictive parameters (impact on treatment strategies). This paper is based on data collected by the Working Group on Cancer Diagnosis Research for the First National Conference on Cancer Research Coordination in April 2004. Data was collated from the databases of Institutions/Universities where the authors are employed, the Ministry of Science, Technology and Innovation (MOSTI) and targeted survey feedback from key cancer researchers. Under the 7th Malaysia Plan, 76 cancer projects were funded through the Intensified Research in Priority Areas (IRPA) scheme of MOSTI, amounting to almost RM15 million of grant money. 47(61.8%) of these projects were substantially in cancer

  18. MicroRNA Detection: Current Technology and Research Strategies

    Science.gov (United States)

    Hunt, Eric A.; Broyles, David; Head, Trajen; Deo, Sapna K.

    2015-07-01

    The relatively new field of microRNA (miR) has experienced rapid growth in methodology associated with its detection and bioanalysis as well as with its role in -omics research, clinical diagnostics, and new therapeutic strategies. The breadth of this area of research and the seemingly exponential increase in number of publications on the subject can present scientists new to the field with a daunting amount of information to evaluate. This review aims to provide a collective overview of miR detection methods by relating conventional, established techniques [such as quantitative reverse transcription polymerase chain reaction (RT-qPCR), microarray, and Northern blotting (NB)] and relatively recent advancements [such as next-generation sequencing (NGS), highly sensitive biosensors, and computational prediction of microRNA/targets] to common miR research strategies. This should guide interested readers toward a more focused study of miR research and the surrounding technology.

  19. Neuroeconomics: cross-currents in research on decision-making

    NARCIS (Netherlands)

    Sanfey, A.G.; Loewenstein, G.; McClure, S.M.; Cohen, J.D.

    2006-01-01

    Despite substantial advances, the question of how we make decisions and judgments continues to pose important challenges for scientific research. Historically, different disciplines have approached this problem using different techniques and assumptions, with few unifying efforts made. However, the

  20. Symposium: Organizational Health Intervention Research: Current Empirical Developments

    DEFF Research Database (Denmark)

    Ipsen, Christine; Jenny, Gregor

    2014-01-01

    This symposium is one of three symposia submitted by the "International organizational health intervention research partnership". The aim of this symposium is to present new empirical developments based on participatory intervention models. All five studies have developed and applied intervention...

  1. Current research situation of titanium alloys in China

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    Titanium and its alloys possess excellent comprehensive properties, and they are widely used in many fields. China pays great attentions to the research on new titanium alloys. This paper mainly reviews the research on new Ti alloys in China, for example, high strength and high toughness Ti alloys, burn resistant Tialloys, high temperature Ti alloys, low cost Ti alloys and so on.New basic theories on Ti alloys developed in China in recent years are also reviewed.

  2. Current research in transcultural psychiatry in the Nordic countries

    DEFF Research Database (Denmark)

    Ekblad, Solvig; Kastrup, Marianne Carisius

    2013-01-01

    This article discusses major themes in recent transcultural psychiatric research in the Nordic countries from 2008 to 2011: (a) epidemiological studies of migration, (b) indigenous populations, and (c) quality of psychiatric care for migrants. Over the past several decades, the populations......, and after migration, with potential effects on their physical, mental, social, and spiritual health. Growing interest in transcultural issues is reflected in the level of scientific research and clinical activity in the field by Nordic physicians, psychologists, social scientists, demographers, medical...

  3. National and International Migration:Reflections on Literature and Some Current Research1

    Institute of Scientific and Technical Information of China (English)

    Nicholas Tapp(Wang Fuwen)

    2013-01-01

    This article gives a review on literature and some current research relevant to na-tional and international migration , and examines the connections between such research in a na-tional context , and the research on international migration .The approaches to migration in migra-tion studies are very complex , and the author suggested that we need to pay attention to all three approaches contrasted by Solinger:the one based on rational calculation , the one based on stress-ing the historico-structural conditions and the one based on social networking analysis .The au-thor also stresses the importance of a network approach taken from the sociology of John Urry in the studies of both national and international migration , and the need to see movement as prima-ry, and productive of place , as much recent anthropological literature has stressed .

  4. Pharmacotherapy for the core symptoms in autistic disorder: current status of the research.

    Science.gov (United States)

    Farmer, Cristan; Thurm, Audrey; Grant, Paul

    2013-03-01

    The current review covers extant literature on pharmacotherapy for core symptoms of autism. The core symptoms of autism include impairments in social interaction and communication, as well as the presence of restricted and repetitive behaviors. There are no known efficacious treatments for the core social symptoms, although effects on repetitive behaviors are indicated with some data. While studies of fenfluramine, secretin, opiates, and mood stabilizers generally find no effect, mixed results suggest more research is needed on antidepressants and atypical antipsychotics. Newer lines of research, including cholinergic and glutamatergic agents and oxytocin, will be of considerable interest in the future. However, research on the treatment of core symptoms is plagued by limitations in study design, statistical power, and other issues inherent to the study of treatments for autism (e.g., heterogeneity of the disorder) that continue to prevent the elucidation of efficacious treatments.

  5. Current Developments in Research on the Teaching of Grammar

    Institute of Scientific and Technical Information of China (English)

    Hossein Nassaji; Sandra Fotos

    2006-01-01

    @@ With the rise of communicative methodology in the late 1970s, the role of grammar instruction in second language learning was downplayed, and it was even suggested that teaching grammar was not only unhelpful but might actually be detrimental.

  6. Current practices and research updates on diabetes mellitus in canine

    OpenAIRE

    Pankaj Kumar; Rashmi Rekha Kumari; Manish Kumar; Sanjiv Kumar; Asit Chakrabarti

    2014-01-01

    Diabetes has evidence in ancient literatures, though recently is being considered as one amongst the most emerging disease condition in both human and companion animals. Diabetes mellitus is one of the common endocrinopathy of dog characterized by hyperglycemia, glycosuria and weight loss. Reports suggests high fraction of canine population suffer with diabetes world over. Studies in different veterinary hospitals of United States suggest increase in cases of canine diabetes and decrease in c...

  7. Current status of quantitative rotational spectroscopy for atmospheric research

    Science.gov (United States)

    Drouin, Brian J.; Wlodarczak, Georges; Colmont, Jean-Marcel; Rohart, Francois

    2004-01-01

    Remote sensing of rotational transitions in the Earth's atmosphere has become an important method for the retrieval of geophysical temperatures, pressures and chemical composition profiles that requires accurate spectral information. This paper highlights the current status of rotational data that are useful for atmospheric measurements, with a discussion of the types the rotational lineshape measurements that are not generally available in either online repository.

  8. 2002–2012: 10 Years of Research Progress in Horizontal-Axis Marine Current Turbines

    Directory of Open Access Journals (Sweden)

    Kai-Wern Ng

    2013-03-01

    Full Text Available Research in marine current energy, including tidal and ocean currents, has undergone significant growth in the past decade. The horizontal-axis marine current turbine is one of the machines used to harness marine current energy, which appears to be the most technologically and economically viable one at this stage. A number of large-scale marine current turbines rated at more than 1 MW have been deployed around the World. Parallel to the development of industry, academic research on horizontal-axis marine current turbines has also shown positive growth. This paper reviews previous research on horizontal-axis marine current turbines and provides a concise overview for future researchers who might be interested in horizontal-axis marine current turbines. The review covers several main aspects, such as: energy assessment, turbine design, wakes, generators, novel modifications and environmental impact. Future trends for research on horizontal-axis marine current turbines are also discussed.

  9. Feeding Infants With Cleft Lip and/or Palate in Brazil: Suggestions to Improve Health Policy and Research

    OpenAIRE

    Gil-Da-Silva-Lopes, VL; Xavier, AC; Klein-Antunes, D; Ferreira, ACRG; Tonocchi, R; Fett-Conte, AC; Silva, RN; Leiriao, VHV; Caramori, LPC; Magna, LA; Amstalden-Mendes, LG

    2013-01-01

    Objective: To verify feeding resources used prior to corrective surgery among cleft babies from Brazil and to discuss suggestions to improve common feeding problems around the world. Design: Cross-sectional descriptive study conducted at eight medical centers. Participants: A total of 215 parents or guardians of cleft children. Methods: Interview based upon a prevalidated questionnaire. The chi-square test and comparison of means by analysis of variance were used; significance level adopted w...

  10. Research Diagnostic criteria for Temporomandibular Disorders: current status & future relevance.

    Science.gov (United States)

    Dworkin, S F

    2010-10-01

    The Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD), published in 1992, was based on international expert recommendations and available empirical data. The major rationale was to offer a putative diagnostic and classification system whose reliability, validity and clinical usefulness for TMD diagnosis and classification could be scientifically evaluated and then revised using an evidence-based model for successive iterations. The present journal issue attests to the accomplishment of that major objective: the RDC/TMD has been translated into 18 languages and used very extensively in international research. One important component of that research has been to yield reliable and valid data resulting in an evidence-based revision of the RDC/TMD now available for continuing research and clinical application. The present article offers recommendations and speculations regarding how the RDC/TMD may continue to serve the function of guiding future research and, most importantly, serve as an evidence-based diagnostic and classification system to aid in the rational choice of clinical care for TMD sufferers around the world.

  11. Material research for environmental sustainability in Thailand: current trends

    Science.gov (United States)

    Niranatlumpong, Panadda; Ramangul, Nudjarin; Dulyaprapan, Pongsak; Nivitchanyong, Siriluck; Udomkitdecha, Werasak

    2015-06-01

    This article covers recent developments of material research in Thailand with a focus on environmental sustainability. Data on Thailand’s consumption and economic growth are briefly discussed to present a relevant snapshot of its economy. A selection of research work is classified into three topics, namely, (a) resource utilization, (b) material engineering and manufacturing, and (c) life cycle efficiency. Material technologies have been developed and implemented to reduce the consumption of materials, energy, and other valuable resources, thus reducing the burden we place on our ecological system. At the same time, product life cycle study allows us to understand the extent of the environmental impact we impart to our planet.

  12. Current research on parenting styles, dimensions, and beliefs.

    Science.gov (United States)

    Smetana, Judith G

    2017-06-01

    For decades, parenting has been characterized in terms of broad global styles, with authoritative parenting seen as most beneficial for children's development. Concerns with greater sensitivity to cultural and contextual variations have led to greater specificity in defining parenting in terms of different parenting dimensions and greater consideration of the role of parenting beliefs in moderating links between parenting and adjustment. New research includes 'domain-specific' models that describe parents as flexibly deploying different practices depending on their goals, children's needs, and the types of behaviors towards which parenting is directed. These trends are described, and directions for future research are discussed. Copyright © 2017 Elsevier Ltd. All rights reserved.

  13. Material research for environmental sustainability in Thailand: current trends.

    Science.gov (United States)

    Niranatlumpong, Panadda; Ramangul, Nudjarin; Dulyaprapan, Pongsak; Nivitchanyong, Siriluck; Udomkitdecha, Werasak

    2015-06-01

    This article covers recent developments of material research in Thailand with a focus on environmental sustainability. Data on Thailand's consumption and economic growth are briefly discussed to present a relevant snapshot of its economy. A selection of research work is classified into three topics, namely, (a) resource utilization, (b) material engineering and manufacturing, and (c) life cycle efficiency. Material technologies have been developed and implemented to reduce the consumption of materials, energy, and other valuable resources, thus reducing the burden we place on our ecological system. At the same time, product life cycle study allows us to understand the extent of the environmental impact we impart to our planet.

  14. Urban heat stress: novel survey suggests health and fitness as future avenue for research and adaptation strategies

    Science.gov (United States)

    Schuster, Christian; Honold, Jasmin; Lauf, Steffen; Lakes, Tobia

    2017-04-01

    Extreme heat has tremendous adverse effects on human health. Heat stress is expected to further increase due to urbanization, an aging population, and global warming. Previous research has identified correlations between extreme heat and mortality. However, the underlying physical, behavioral, environmental, and social risk factors remain largely unknown and comprehensive quantitative investigation on an individual level is lacking. We conducted a new cross-sectional household questionnaire survey to analyze individual heat impairment (self-assessed and reported symptoms) and a large set of potential risk factors in the city of Berlin, Germany. This unique dataset (n = 474) allows for the investigation of new relationships, especially between health/fitness and urban heat stress. Our analysis found previously undocumented associations, leading us to generate new hypotheses for future research: various health/fitness variables returned the strongest associations with individual heat stress. Our primary hypothesis is that age, the most commonly used risk factor, is outperformed by health/fitness as a dominant risk factor. Related variables seem to more accurately represent humans’ cardiovascular capacity to handle elevated temperature. Among them, active travel was associated with reduced heat stress. We observed statistical associations for heat exposure regarding the individual living space but not for the neighborhood environment. Heat stress research should further investigate individual risk factors of heat stress using quantitative methodologies. It should focus more on health and fitness and systematically explore their role in adaptation strategies. The potential of health and fitness to reduce urban heat stress risk means that encouraging active travel could be an effective adaptation strategy. Through reduced CO2 emissions from urban transport, societies could reap double rewards by addressing two root causes of urban heat stress: population health and

  15. Current research activity in the measurement of thorium and the identification of future research needs.

    Science.gov (United States)

    White, M A; Howe, A M; Rosen, P; Holmes, L

    2001-01-01

    A pre-requisite in the setting and enforcement of regulatory limits for exposure to thorium in the workplace is that thorium and its progeny can be accurately measured. Literature surveys have shown that the majority of thorium measurements were performed using either a radiochemical technique, such as alpha or gamma spectroscopy, or ICP-MS. For many methods. there was a separation step to isolate and pre-concentrate thorium from the sample matrix. Thorium was most commonly measured in geological matrices and industrial materials. A survey of current research activity was performed through distribution of a questionnaire to laboratories and national centres. From the rcsponses, four areas of current activity were identified: (i) development of methods for low level thorium determination, (ii) biological monitoring and metabolism of thorium, (iii) environmental monitoring for thorium, and (iv) health risks from X ray contract media. Two key areas for priority research were identified by the thorium Thematic Network: namely sample preparation methods and for traceable standards and reference materials for thorium analysis.

  16. Research on Predicting Drive Current of Shipborne Satcom Antenna

    Directory of Open Access Journals (Sweden)

    Kong Jinping

    2015-01-01

    Full Text Available Predicting the effect of antenna wind load on servo system precisely is meaningful to ensure the safety of satcom antenna on operation, which can avoid overload operation. In this paper, the computational fluid dynamics is used to proceed numerical computation on the pressure distribution of the reflector and torque of drive shaft under different wind speed, windward angle and angle of pitch of the antenna. The simulation model is built under MATLAB/Simulink simulation environment, and the drive current of the antenna servo system is analyzed under wind load effect and ship swing. Then, a method of predicting drive current of antenna servo system according to the wind speed, wind direction and attitude of the antenna is concluded. And this method is verified by simulation at last.

  17. Research on current e-commerce of tourism in China

    OpenAIRE

    Lei, Jun

    2016-01-01

    The rapid development of e-commerce in China has been accompanied by a similar development in tourism-based e-commerce. Taking the network as the medium, e-commerce has already become the new model for tourism transactions in the information age: By building one convenient bridge between tourism-based enterprises and tourists, can directly influence the profitability of enterprises. The paper will introduce the current development of tourism-based e-commerce websites, by firstly examining...

  18. Current trends in safety testing and toxicological research

    Science.gov (United States)

    Zbinden, G.

    1982-06-01

    The paper reviews current concepts of toxicological evaluation of new drugs and other chemicals. Instead of completing a predetermined check-list toxicologists now consider the potential adverse effects of the substances under actual conditions of use. They then design experimental models which have a high probability to predict the toxic effects. Moreover, the enhanced susceptibilities of special risk populations is more and more taken into consideration.

  19. Research on Low Power Marine Current Power Generation System

    Directory of Open Access Journals (Sweden)

    Dongkai Peng

    2013-09-01

    Full Text Available This study proposes a simple topological structure and power control method for a small scale stand alone marine current system, in which a diode rectifier, DC/DC boost converter for the maximum power control, battery as a storage element and a single phase inverter to link with load. The study establishes the steady-state mathematical model of marine current power generation system and derives the formula between the maximum power point and dc battery voltage. Then use the measurements of DC voltage and DC current to obtain Maximum Power Point Tracking (MPPT by controlling the duty cycle of the boost converter switch in order to simplify the system structure and the control strategies. In this case, the hill climbing searching algorithm is employed to get maximum power point and the double closed loops control strategy is used to improve the dynamic and static performance of single phase inverter. The simulation model is developed in MATLAB/Simulink. And the control method is executed in dSPACE1104 real-time platform. The simulation and experimental results demonstrate the feasibility and validity of the proposed control strategies.

  20. Talent management : Current theories and future research directions

    NARCIS (Netherlands)

    Al Ariss, A.; Cascio, W.F.; Paauwe, J.

    2014-01-01

    Research on Talent Management (TM) has been lagging behind businesses in offering vision and leadership in this field. After sketching a comprehensive outline of knowledge about TM, theoretical as well as practical, we introduce the papers in this special issue and their important contributions.

  1. Applying Current Theory and Research in Career Exploration to Practice.

    Science.gov (United States)

    Blustein, David L.

    1992-01-01

    Provides selected review of two lines of recent research on career exploration (identifying antecedents of exploratory activity and application of information processes biases to career exploration), with specific focus on applications for counseling practice. Describes relevant counseling interventions and concludes with summary of six goals to…

  2. Current Research and Opportunities to Address Environmental Asbestos Exposures

    Science.gov (United States)

    Asbestos-related diseases continue to result in approximately 120,000 deaths every year in the United States and worldwide.Although extensive research has been conducted on health effects of occupational exposures to asbestos, many issues related to environmental asbestos exposur...

  3. Behavioral Marital Therapy: Current Trends in Research, Assessment and Practice.

    Science.gov (United States)

    Jacobson, Neil S.

    1980-01-01

    Behavioral Marital Therapy (BMT) is clinically useful because it includes elaborating procedures, modifying the spouse's self-defeating cognitions, and moving toward early intervention and prevention. Each article in this issue of American Journal of Family Therapy focuses on innovations in BMT, either in research or practice. (Author/NRB)

  4. Dyslexia and the Brain: What Does Current Research Tell Us?

    Science.gov (United States)

    Hudson, Roxanne F.; High, Leslie; Al Otaiba, Stephanie

    2007-01-01

    Dyslexia is a disorder of the language-processing systems in the brain. It is a specific learning disability in reading that often affects spelling as well. This article describes: (1) Common characteristics experienced by people with dyslexia or reading disabilities; (2) Common misconceptions about dyslexia; (3) What brain research tell us about…

  5. Current Relevance of Zetetics to Library Research and Library Instruction.

    Science.gov (United States)

    Davis, Marta A.; Davis, Harry O.

    1996-01-01

    Explains zetetics which involve theories of research and epistemology and discusses its relevance to library science. Topics include library literacy, and the use of an information matrix to help library patrons understand what information they have and what they need to find. (Author/LRW)

  6. Materials for hydrogen storage: current research trends and perspectives.

    Science.gov (United States)

    van den Berg, Annemieke W C; Areán, Carlos Otero

    2008-02-14

    Storage and transport of hydrogen constitutes a key enabling technology for the advent of a hydrogen-based energy transition. Main research trends on hydrogen storage materials, including metal hydrides, porous adsorbents and hydrogen clathrates, are reviewed with a focus on recent developments and an appraisal of the challenges ahead. .

  7. Current research in Spain on walnut for wood production

    Science.gov (United States)

    Neus Alet& #224; Neus NO-VALUE

    2004-01-01

    The Department of Mediterranean Trees at the Institut de Recerca i Tecnologia Agroalimentaries (IRTA) in Spain initiated a research program in 1993 to examine the variability among walnut species for wood production and to establish orchards with improved selections. The main objective of the programme is to obtain superior Persian walnut (Juglans regia...

  8. Current Research and Opportunities to Address Environmental Asbestos Exposures

    Science.gov (United States)

    Asbestos-related diseases continue to result in approximately 120,000 deaths every year in the United States and worldwide.Although extensive research has been conducted on health effects of occupational exposures to asbestos, many issues related to environmental asbestos exposur...

  9. Fire management and research in the Kruger National Park, with suggestions on the detection of thresholds of potential concern

    Directory of Open Access Journals (Sweden)

    B.W. Van Wilgen

    1998-01-01

    Full Text Available This paper reviews the options for management of the savanna ecosystems of the Kruger National Park using fire. The major goals of management have shifted from attempts to use fire to achieve a stable vegetation composition, to one of recognising that savanna ecosystems are in constant flux. Fire is a major form of disturbance that helps to maintain a state of flux, and thus to conserve biodiversity. Three candidate approaches for fire management have been put forward@the lightning fire approach, the patch mosaic burning approach, and an approach based on the assessment of ecological criteria. These approaches differ in their underlying philosophies, but not necessarily in their outcomes, although this cannot be predicted with confidence. We propose, therefore, that patterns of fire frequency, season, intensity and spatial distribution be recorded and monitored, and that these patterns should serve as surrogate measures of biodiversity. Guidelines for the definition of thresholds of potential concern with regard to these patterns are discussed. The monitoring of both fire patterns and trends in plant and animal populations can be used to identify interactions between fire and the components of the ecosystem, and these in turn can be used to define a relevant research agenda. The role of management in monitoring and assessing fire patterns (previously regarded as a research responsibility is emphasised. Convergence in the patterns of fire that result from the different management approaches could also serve as a basis for merging some or all of these approaches in order to simplify management.

  10. Researches on regenerative medicine——current state and prospect

    Institute of Scientific and Technical Information of China (English)

    WANG Zheng-guo; XIAO Kai

    2012-01-01

    Since 1980s,the rapid development of tissue engineering and stem cell research has pushed regenerative medicine to a new fastigium,and regenerative medicine has become a noticeable research field in the international biology and medicine.In China,about 100 million patients need repair and regeneration treatment every year,while the number is much larger in the world.Regenerative medicine could provide effective salvation for these patients.Both Chinese Academy of Sciences and Chinese Academy of Engineering have made roadmaps of 2010-2050 and 2011-2030 for regenerative medicine.The final goal of the two roadmaps is to make China go up to leading position in most research aspects of regenerative medicine.In accord with this strategy,the government and some enterprises have invested 3-5 billion RMB (0.5-0.8 billion USD)for the research on regenerative medicine.In order to push the translation of regenerative medicine forward - from bench to bedside,a strategic alliance has been established.and it includes 27 top-level research institutes,medical institutes,colleges,universities and enterprises in the field of stem cell and regeneration medicine.Recently the journal,Science,has published a special issue-Regenerative Medicine in China,consisting of 35 papers dealing with stem cell and regeneration,tissue engineering and regeneration,trauma and regeneration and bases for tissue repair and regenerative medicine.It is predicated that a greater breakthrough in theory and practice of regenerative medicine will be achieved in the near future (20 to 30 years).

  11. Icing Branch Current Research Activities in Icing Physics

    Science.gov (United States)

    Vargas, Mario

    2009-01-01

    Current development: A grid block transformation scheme which allows the input of grids in arbitrary reference frames, the use of mirror planes, and grids with relative velocities has been developed. A simple ice crystal and sand particle bouncing scheme has been included. Added an SLD splashing model based on that developed by William Wright for the LEWICE 3.2.2 software. A new area based collection efficiency algorithm will be incorporated which calculates trajectories from inflow block boundaries to outflow block boundaries. This method will be used for calculating and passing collection efficiency data between blade rows for turbo-machinery calculations.

  12. Current Research and Development of Chemotherapeutic Agents for Melanoma

    Directory of Open Access Journals (Sweden)

    Kyaw Minn Hsan

    2010-04-01

    Full Text Available Cutaneous malignant melanoma is the most lethal form of skin cancer and an increasingly common disease worldwide. It remains one of the most treatment-refractory malignancies. The current treatment options for patients with metastatic melanoma are limited and in most cases non-curative. This review focuses on conventional chemotherapeutic drugs for melanoma treatment, by a single or combinational agent approach, but also summarizes some potential novel phytoagents discovered from dietary vegetables or traditional herbal medicines as alternative options or future medicine for melanoma prevention. We explore the mode of actions of these natural phytoagents against metastatic melanoma.

  13. Conceptual knowledge representation: A cross-section of current research.

    Science.gov (United States)

    Rogers, Timothy T; Wolmetz, Michael

    2016-01-01

    How is conceptual knowledge encoded in the brain? This special issue of Cognitive Neuropsychology takes stock of current efforts to answer this question through a variety of methods and perspectives. Across this work, three questions recur, each fundamental to knowledge representation in the mind and brain. First, what are the elements of conceptual representation? Second, to what extent are conceptual representations embodied in sensory and motor systems? Third, how are conceptual representations shaped by context, especially linguistic context? In this introductory article we provide relevant background on these themes and introduce how they are addressed by our contributing authors.

  14. [Musculoskeletal shock wave therapy--current database of clinical research].

    Science.gov (United States)

    Rompe, J D; Buch, M; Gerdesmeyer, L; Haake, M; Loew, M; Maier, M; Heine, J

    2002-01-01

    During the past decade application of extracorporal shock waves became an established procedure for the treatment of various musculoskeletal diseases in Germany. Up to now the positive results of prospective randomised controlled trials have been published for the treatment of plantar fasciitis, lateral elbow epicondylitis (tennis elbow), and of calcifying tendinitis of the rotator cuff. Most recently, contradicting results of prospective randomised placebo-controlled trials with adequate sample size calculation have been reported. The goal of this review is to present information about the current clinical database on extracorporeal shock wave treatment (ESWT).

  15. Current research on drugs and vaccines for fighting bird flu.

    Science.gov (United States)

    Wiwanitkit, Viroj

    2007-12-01

    Bird flu, or avian flu, caused by the H5N1 virus, is of concern worldwide. The antiviral drugs oseltamivir and zanamivir have been used to treat human cases, and resistance has been reported. Studies on the molecular mechanisms of antiviral resistance are needed to understand the problem and to aid future drug development. Control of a major outbreak would require a vaccine, but current manufacturing technology is not adequate to support influenza vaccine production in the event of an avian influenza outbreak.

  16. Incredible Years parenting interventions: current effectiveness research and future directions.

    Science.gov (United States)

    Gardner, Frances; Leijten, Patty

    2017-06-01

    The Incredible Years parenting intervention is a social learning theory-based programme for reducing children's conduct problems. Dozens of randomized trials, many by independent investigators, find consistent effects of Incredible Years on children's conduct problems across multiple countries and settings. However, in common with other interventions, these average effects hide much variability in the responses of individual children and families. Innovative moderator research is needed to enhance scientific understanding of why individual children and parents respond differently to intervention. Additionally, research is needed to test whether there are ways to make Incredible Years more effective and accessible for families and service providers, especially in low resource settings, by developing innovative delivery systems using new media, and by systematically testing for essential components of parenting interventions. Copyright © 2017. Published by Elsevier Ltd.

  17. Current electroconvulsive therapy practice and research in the geriatric population

    Science.gov (United States)

    Kerner, Nancy; Prudic, Joan

    2014-01-01

    SUMMARY Electroconvulsive therapy (ECT) is utilized worldwide for various severe and treatment-resistant psychiatric disorders. Research studies have shown that ECT is the most effective and rapid treatment available for elderly patients with depression, bipolar disorder and psychosis. For patients who suffer from intractable catatonia and neuroleptic malignant syndrome, ECT can be life saving. For elderly patients who cannot tolerate or respond poorly to medications and who are at a high risk for drug-induced toxicity or toxic drug interactions, ECT is the safest treatment option. Organic causes are frequently associated with late-life onset of neuropsychiatric conditions, such as parkinsonism, dementia and stroke. ECT has proven to be efficacious even when these conditions are present. During the next decade, research studies should focus on the use of ECT as a synergistic therapy, to enhance other biological and psychological treatments, and prevent symptom relapse and recurrence. PMID:24778709

  18. Opening the "black box" of current creativity research

    DEFF Research Database (Denmark)

    Hoffmann Birk, Rasmus; Ernø, Steffen

    value" or none at all. Creativity was mostly measured with different types of divergent thinking tests. There appears to be a lack of deeper theoretical and methodological discussions of creativity in the literature, which creates a disconnection between definitions, methodologies and the interpretation......This presentation aims to problematise the ways in which creativity is defined and measured in recent studies on the topic. For this purpose, we analyzed 58 articles on creativity, selected from within the sub-fields of neuropsychology, psychometrics and developmental psychology published from 2009......-2012. The sub-fields were chosen because of their prominence in psychological research and research on creativity. The articles were procured from the PsycINFO database, with selection criteria being that they must be peer-reviewed and empirical studies. Typical definitions of creativity were "novelty plus...

  19. CYBERQUEER – MAJOR TOPICS AND ISSUES IN CURRENT RESEARCH

    Directory of Open Access Journals (Sweden)

    SIMONA RODAT

    2014-12-01

    Full Text Available The emergence of the opportunities opened by the internet raises also questions of interest for research regarding the extent to which these have an impact on the formations of non heterosexual life and on the experience of marginalised sexual identities. There have been different approaches in this regard and answers vary from optimistic and utopian appraisals concerning cyberspace in the early 90s to the more moderate and sceptic visions in the 2000s. Starting from this framework of debates, the present paper aims to explore the meaning of the term “cyberqueer”, including the theoretical context of its occurrence, to briefly highlight some critical considerations relating to cyberqueer research and to look over the main recurrent themes linked up with this concept, such as queer and cyberqueer identity, body and (disembodied practices and the forthcoming process of blurring the dividing boundaries between real/virtual, online/offline and public/private

  20. AAS Nova and Astrobites: Making current astronomy research accessible

    Science.gov (United States)

    Kohler, Susanna; Astrobites Team

    2016-10-01

    AAS Nova and Astrobites are two resources available for astronomers, astronomy students, and astronomy enthusiasts to keep up with some of the most recent research published across the field of astronomy. Both supported by the AAS, these two daily astrophysical literature blogs provide accessible summaries of recent publications on the arXiv and in AAS journals. We present the goals, content, and readership of AAS Nova and Astrobites, and discuss how they might be used as tools in the undergraduate classroom.

  1. Current Status and Trend of Forest Hydrological Services Market Research

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Of the many services that forests provide, hydrological services are among the most valuable, and it becomes more scarce with the growing demands by human beings. As a kind of incentive measure for protecting forest, forest hydrological services markets have been developed in many countries around the world and some valuable experiences have been achieved. The paper reviews the experiments carried out in the world and their research findings on forest hydrological services market, and presents the issues to...

  2. Ubiquitous Wireless Computing: Current Research Progress, Challenging, and Future Directions

    OpenAIRE

    Elyas, Palantei

    2014-01-01

    - The aggressive research activities and generous studies focusing on the ubiquitous mobile computing carried-out during the last two decades have gained very tremendous outcomes to apply in broad areas of modern society lives. In the near future, the computing technology application is highly possible to emerge as the dominant method to connect any objects to the global ICT infrastructure, the internet. This talk mainly discusses several R&D achievements performed during the last five yea...

  3. Music therapy in cardiac health care: current issues in research.

    Science.gov (United States)

    Hanser, Suzanne B

    2014-01-01

    Music therapy is a service that has become more prevalent as an adjunct to medical practice-as its evidence base expands and music therapists begin to join the cardiology team in every phase of care, from the most serious cases to those maintaining good heart health. Although applications of music medicine, primarily listening to short segments of music, are capable of stabilizing vital signs and managing symptoms in the short-term, music therapy interventions by a qualified practitioner are showing promise in establishing deeper and more lasting impact. On the basis of mind-body approaches, stress/coping models, the neuromatrix theory of pain, and entrainment, music therapy capitalizes on the ability of music to affect the autonomic nervous system. Although only a limited number of randomized controlled trials pinpoint the efficacy of specific music therapy interventions, qualitative research reveals some profound outcomes in certain individuals. A depth of understanding related to the experience of living with a cardiovascular disease can be gained through music therapy approaches such as nonverbal music psychotherapy and guided imagery and music. The multifaceted nature of musical responsiveness contributes to strong individual variability and must be taken into account in the development of research protocols for future music therapy and music medicine interventions. The extant research provides a foundation for exploring the many potential psychosocial, physiological, and spiritual outcomes of a music therapy service for cardiology patients.

  4. The Communication Research in Spain. Historical evolution and current challenges

    Directory of Open Access Journals (Sweden)

    Dr. Manuel Martínez Nicolás - manuel.martinez.nicolas@urjc.es

    2009-01-01

    Full Text Available We propose in this paper an approach to the history of Communication Research in Spain, taking into account the scientific production and the structure and historical context in which the scientific community interested in this field have performed their work. For this task we have established a temporary frame beginning from the moment communication became an autonomous field of research and education in Spain, during the mid-sixties, until present time. This period has been divided into three stages, typically defined as emergence, consolidation and development (or maturing of communication studies in Spain. In each of these stages, the scientific community interested in communication research have worked in different social, academic and epistemic or scientific contexts. These particular conditions contribute to understanding the different orientations which have inspired historical communication research in Spain (research objects, theoretical and methodological approaches, contributions and limitations.Traducción supervisada por la Dda. María Teresa Durán Sánchez (ULPGC.En este trabajo se propone una aproximación a la historia de la investigación sobre comunicación en España poniendo en relación la producción científica con las características, estructura y condiciones históricas en las que ha desempeñado su trabajo la comunidad científica interesada en este ámbito. Para ello, se establece un marco temporal que arranca en el momento de la constitución de la comunicación como campo de investigación (y de docencia autónomo, a mediados de la década de los sesenta, y llega hasta la actualidad. Consideramos que en el curso de este periodo pueden distinguirse no menos de tres etapas, que convencionalmente se han denominado de emergencia, consolidación y desarrollo (o maduración de los estudios sobre comunicación en España. En cada una de estas etapas, la comunidad científica interesada en la investigación comunicativa

  5. Eating disorders and suicidality: what we know, what we don't know, and suggestions for future research.

    Science.gov (United States)

    Smith, April R; Zuromski, Kelly L; Dodd, Dorian R

    2017-08-12

    Suicide is the second leading cause of death among individuals with anorexia nervosa (AN), and suicidal behavior is elevated in bulimia nervosa (BN) and binge eating disorder (BED) relative to the general population. This paper reviews the suicidality literature within each ED, as well as theoretical explanations for the elevated risk for suicidality among those with EDs. Approximately one-quarter to one-third of people with AN, BN, or BED have thought about suicide, and one-quarter to one-third of people with AN and BN have attempted suicide. Relative to gender and aged matched comparison groups, individuals with AN are 18 times more likely to die by suicide, and individuals with BN are seven times more likely to die by suicide. However, the majority of the research in this area is cross-sectional or retrospective, which leaves the timing of the mortality risk unclear. Longitudinal work that is designed to examine dynamic and acute fluctuations in suicidality among ED samples is needed in order to determine meaningful risk factors. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. Workshop Report on Atomic Bomb Dosimetry--Residual Radiation Exposure: Recent Research and Suggestions for Future Studies

    Energy Technology Data Exchange (ETDEWEB)

    None

    2013-06-06

    There is a need for accurate dosimetry for studies of health effects in the Japanese atomic bomb survivors because of the important role that these studies play in worldwide radiation protection standards. International experts have developed dosimetry systems, such as the Dosimetry System 2002 (DS02), which assess the initial radiation exposure to gamma rays and neutrons but only briefly consider the possibility of some minimal contribution to the total body dose by residual radiation exposure. In recognition of the need for an up-to-date review of the topic of residual radiation exposure in Hiroshima and Nagasaki, recently reported studies were reviewed at a technical session at the 57th Annual Meeting of the Health Physics Society in Sacramento, California, 22-26 July 2012. A one-day workshop was also held to provide time for detailed discussion of these newer studies and to evaluate their potential use in clarifying the residual radiation exposures to the atomic-bomb survivors at Hiroshima and Nagasaki. Suggestions for possible future studies are also included in this workshop report.

  7. Workshop report on atomic bomb dosimetry-residual radiation exposure: recent research and suggestions for future studies.

    Science.gov (United States)

    Kerr, George D; Egbert, Stephen D; Al-Nabulsi, Isaf; Beck, Harold L; Cullings, Harry M; Endo, Satoru; Hoshi, Masaharu; Imanaka, Tetsuji; Kaul, Dean C; Maruyama, Satoshi; Reeves, Glen I; Ruehm, Werner; Sakaguchi, Aya; Simon, Steven L; Spriggs, Gregory D; Stram, Daniel O; Tonda, Tetsuji; Weiss, Joseph F; Weitz, Ronald L; Young, Robert W

    2013-08-01

    There is a need for accurate dosimetry for studies of health effects in the Japanese atomic bomb survivors because of the important role that these studies play in worldwide radiation protection standards. International experts have developed dosimetry systems, such as the Dosimetry System 2002 (DS02), which assess the initial radiation exposure to gamma rays and neutrons but only briefly consider the possibility of some minimal contribution to the total body dose by residual radiation exposure. In recognition of the need for an up-to-date review of the topic of residual radiation exposure in Hiroshima and Nagasaki, recently reported studies were reviewed at a technical session at the 57th Annual Meeting of the Health Physics Society in Sacramento, California, 22-26 July 2012. A one-day workshop was also held to provide time for detailed discussion of these newer studies and to evaluate their potential use in clarifying the residual radiation exposures to the atomic-bomb survivors at Hiroshima and Nagasaki. Suggestions for possible future studies are also included in this workshop report.

  8. Current status of neutron activation analysis in HANARO Research Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Yong Sam; Moon, Jong Hwa; Sohn, Jae Min [Korea Atomic Energy Research Institute, Daejeon (Korea)

    2003-03-01

    The facilities for neutron activation analysis in the HANARO (Hi-flux Advanced Neutron Application Research Reactor) are described and the main applications of NAA (Neutron Activation Analysis) are reviewed. The sample irradiation tube, automatic and manual pneumatic transfer system were installed at three irradiation holes of HANARO at the end of 1995. The performance of the NAA facility was examined to identify the characteristics of the tube transfer system, irradiation sites and custom-made polyethylene irradiation capsule. The available thermal neutron fluxes at irradiation sites are in the range of 3 x 10{sup 13} - 1 x 10{sup 14} n/cm{sup 2}{center_dot}s and cadmium ratios are in 15 - 250. For an automatic sample changer for gamma-ray counting, a domestic product was designed and manufactured. An integrated computer program (Labview) to analyse the content was developed. In 2001, PGNAA (Prompt Gamma Neutron Activation Analysis) facility has been installed using a diffracted neutron beam of ST1. NAA has been applied in the trace component analysis of nuclear, geological, biological, environmental and high purity materials, and various polymers for research and development. The improvement of analytical procedures and establishment of an analytical quality control and assurance system were studied. Applied research and development for the environment, industry and human health by NAA and its standardization were carried out. For the application of the KOLAS (Korea Laboratory Accreditation Scheme), evaluation of measurement uncertainty and proficiency testing of reference materials were performed. Also to verify the reliability and to validate analytical results, intercomparison studies between laboratories were carried out. (author)

  9. Current Research in Aircraft Tire Design and Performance

    Science.gov (United States)

    Tanner, J. A.; Mccarthy, J. L.; Clark, S. K.

    1981-01-01

    A review of the tire research programs which address the various needs identified by landing gear designers and airplane users is presented. The experimental programs are designed to increase tire tread lifetimes, relate static and dynamic tire properties, establish the tire hydroplaning spin up speed, study gear response to tire failures, and define tire temperature profiles during taxi, braking, and cornering operations. The analytical programs are aimed at providing insights into the mechanisms of heat generation in rolling tires and developing the tools necessary to streamline the tire design process and to aid in the analysis of landing gear problems.

  10. Current Status of Dengue Therapeutics Research and Development.

    Science.gov (United States)

    Low, Jenny G H; Ooi, Eng Eong; Vasudevan, Subhash G

    2017-03-01

    Dengue is a significant global health problem. Even though a vaccine against dengue is now available, which is a notable achievement, its long-term protective efficacy against each of the 4 dengue virus serotypes remains to be definitively determined. Consequently, drugs directed at the viral targets or critical host mechanisms that can be used safely as prophylaxis or treatment to effectively ameliorate disease or reduce disease severity and fatalities are still needed to reduce the burden of dengue. This review will provide a brief account of the status of therapeutics research and development for dengue. © The Author 2016. Published by Oxford University Press for the Infectious Diseases Society of America.

  11. Current status, research progress and future plan of Kartini research reactor

    Energy Technology Data Exchange (ETDEWEB)

    Sardjono, Y.; Syarip; Tjiptono, T.W. [Yogyakarta Nuclear Research Center, Batan (Indonesia)

    1999-10-01

    The current status, research progress and future plan of the Kartini Research Reactor (KRR) is presented. The measurements of axial burn-up distributions for each fuel element by gamma scanning techniques, core axial power distribution display, fuel management for safeguards purpose as well as some research progress activities i.e.; utilization of beamport for: neutron radiography, application neutron activation analysis and history record of KRR power operations is also presented. The KRR is 100 kW pool water reactor type which uses natural circulation and provided by: five beamports in which one of them already coupled with natural uranium subcritical assembly, two thermalizing columns in which one of them is prepared for developing Boron Neutron Capture Therapy (BNCT), two rabbit systems utilized for special analysis uranium ore by delayed neutron counting techniques, one center timbre and 40 irradiation rack (lazy susan) for neutron activation analysis. The KRR was constructed as a second research reactor in Indonesia with special purpose for training and education, high safety margin with involve in high negative temperature coefficient which achieved its first criticality on January 25, 1979. The maximum power level on first criticality is 50 kW and since August 1981 up to now is operating 100 kW. Base on the KRR design limit, it is planned to increase the power level up to 250 kW in the future plan. The preliminary activities such as Non Destructive Testing (NDT) for some reactor components especially water tank and thermal column should be done before decided to increase power level. (author)

  12. 76 FR 38399 - Assessing the Current Research, Policy, and Practice Environment in Public Health Genomics

    Science.gov (United States)

    2011-06-30

    ... HUMAN SERVICES Centers for Disease Control and Prevention Assessing the Current Research, Policy, and..., and other information helpful to assess the current research, policy, and practice environment in... Control and Prevention (CDC) has worked to integrate genomics into public health research, policy,...

  13. Strength and conditioning in tennis: current research and practice.

    Science.gov (United States)

    Reid, Machar; Schneiker, Knut

    2008-06-01

    Virtually all professional tennis players are in continuous pursuit of enhanced performance. With the modern game becoming increasingly dynamic and tournament schedules no less demanding, the importance of physical fitness is well accepted. Indeed, most professional tennis players resource strength and conditioning specialists on a full- or part-time basis. As tennis play is characterised by intricate bio-energetics, planning specific strength and conditioning interventions represents a significant challenge for the specialist. Further, where game physiology and mechanics have been described extensively, critiques of the efficacy of different training initiatives are far less common. This review therefore considers the current scientific, tennis-specific fitness training evidence base in light of contemporary conditioning, and more particularly resistance training, practices.

  14. Caffeine and cardiovascular diseases: critical review of current research.

    Science.gov (United States)

    Zulli, Anthony; Smith, Renee M; Kubatka, Peter; Novak, Jan; Uehara, Yoshio; Loftus, Hayley; Qaradakhi, Tawar; Pohanka, Miroslav; Kobyliak, Nazarii; Zagatina, Angela; Klimas, Jan; Hayes, Alan; La Rocca, Giampiero; Soucek, Miroslav; Kruzliak, Peter

    2016-06-01

    Caffeine is a most widely consumed physiological stimulant worldwide, which is consumed via natural sources, such as coffee and tea, and now marketed sources such as energy drinks and other dietary supplements. This wide use has led to concerns regarding the safety of caffeine and its proposed beneficial role in alertness, performance and energy expenditure and side effects in the cardiovascular system. The question remains "Which dose is safe?", as the population does not appear to adhere to the strict guidelines listed on caffeine consumption. Studies in humans and animal models yield controversial results, which can be explained by population, type and dose of caffeine and low statistical power. This review will focus on comprehensive and critical review of the current literature and provide an avenue for further study.

  15. [Organ cryopreservation: current status of research carried out in Grenoble].

    Science.gov (United States)

    Descotes, J L; Payen, E; Rambeaud, J J; Peuridieu, J F; Baudot, A; Odin, J; Mazuer, J; Boutron, P; Delon-Martin, C; Dupeyre, R

    1995-12-01

    After discussing the problem of organ cryopreservation and reviewing the current data available on this subject, the Grenoble project is presented. Physical and biological studies have been combined with experimentation of autologous renal transplantation in rabbits to assess the functional value of the retransplanted organ after treatment and cooling. Renal resistances are measured during perfusion of the kidney with the cryoprotective solution. In order to verify the homogeneity of the cryoprotector concentration in the organ, on NMR spectral imaging test has been developed. A new rapid imaging method now allows real time monitoring of concentration variations during perfusion. In addition to concentration and homogeneity, analysis of local spectra also provides information about the local temperature de the kidney.

  16. Current research on biological effects of low-level exposures

    Energy Technology Data Exchange (ETDEWEB)

    Sagan, L.A.

    1994-12-31

    Rather substantial numbers of industrial chemicals, pharmaceuticals, and radiation display U-shaped or seemingly paradoxical dose-response relationships. A limited listing of studies providing examples of data fitting the U-shaped curve has been published. This array suggests that the U-shaped response is broadly generalizable and therefore potentially of considerable significance in the toxicological and public health domains. In fact, in 1992 and 1993, three conferences (Japan, United States, and China) were held exclusively on the topic of the biological effects of low doses of chemicals and radioactivity with articular emphasis on U-shaped curves. Substantial efforts have been made at understanding this observation.

  17. A focus on the state of the art of food waste/losses issue and suggestions for future researches.

    Science.gov (United States)

    Muriana, Cinzia

    2017-07-05

    Today, the role of the supply chain (SC) strategies in Food-Waste/Losses (F-W/L) generation is neglected, because F-W/L are generally considered an unavoidable consequence of accidental events. Therefore, only operating plans are today put into practice, which aim at reducing the impact of product losses along the SC. This involves that structured analyses and strategic SC approaches are not available for the prevention/minimization of F-W/L. The paper aims at changing the perspective, and promoting the hypothesis that generation of F-W/L mainly depends on the SC strategies put into practice that are usually optimized on the basis of the market demand. The paper considers the F-W/L an intrinsic characteristic of the SC, which must be put in relation with the market demand and the shelf life of products, for given boundary conditions (legal constraints, politic decisions, climatic and micro macro-economic factors). Thus, the paper aims at reviewing the state of the art of the F-W/L issue, and proposing new research topics in the field of the prevention and minimization of F-W/L, by focusing on: (i) the forecasting of F-W/L, the implementation of adaptive-holistic approaches that model the non-stationary and holistic behaviour of the phenomenon; (ii) the determination of analytical conditions that entail the generation of F-W/L, in relation to the implementation of specific SC strategies; (iii) the study of mathematical models for the assessment of the shelf life, and the evaluation of innovative technologies, which enable the shelf life monitoring; (iv) the study of new shelf life-dependent demand models based on the consumer-utility theory; (v) the redesign of the logistic SC management models, by proposing new SC coordination models, planning and replenishment strategies, and pricing models, for the prevention/minimization of the predictable component of F-W/L; (vi) the design of new risk assessment plans for the management of the accidental component of F

  18. Sediment pollution of the Elbe River side structures - current research

    Science.gov (United States)

    Chalupova, Dagmar; Janský, Bohumír

    2016-04-01

    The contribution brings the summarized results of a long-term research on sediment pollution of side structures of the Elbe River over the last 14 years. The investigation has been focused on old anthropogenic pollution of sediment cores taken from fluvial lakes and floodplain, as the sampling of deeper sediments outside the riverbed is not a part of systematic monitoring of sediment pollution of the Elbe. The Elbe River floodplain has been influenced by human activities since the Middle Ages, but the main anthropogenic pollution have been produced in the 20th century. The studied localities were chosen with the respect to the distance from the source of industrial pollution, the intensity of hydrological communication with the river and the surrounding landuse to determine the extend and the level of anthropogenic contamination in the Elbe River floodplain ecosystem. Apart from bathymetric measurements, observation of the hydrological regime in several fluvial lakes or water quality sampling at some localities, the research was focused above all on determination of metal concentrations (Ag, Cd, Cr, Cu, Fe, Hg, Mn, Pb, Zn) in all taken sediment cores, specific organic compounds (PCBs, DDT, HCH, HCB, PAHs etc.), total organic carbon at some localities and grain structure analyses. The data were also compared with the results of systematic sediment monitoring from the nearest riverbed sampling stations on the Elbe River. The highest concentrations of metals and specific organic compounds were determined in the sediments taken from fluvial lakes and floodplain (Zimní přístav PARAMO, Rosice fuvial Lake, Libiš pool etc.) situated in the vicinity of the main Elbe River polluters - Synthesia chemical plant and PARAMO refinery in Pardubice or Spolana chemical plant near Neratovice. However, there was also determined a significant role of the hydrological communication with the river proved with lower sediment pollution in separated localities. The realization of the

  19. The Development and Current State of Translation Process Research

    DEFF Research Database (Denmark)

    Lykke Jakobsen, Arnt

    2014-01-01

    which simultaneously tracks the translator’s eye movements across a screen displaying both a source text and the translator’s emerging translation. This research method was developed as a means of qualifying and strengthening translation process hypotheses based on verbal reports by providing additional...... remains inaccessible to outside observation. What mental processes underlie measurable (micro)behaviour can only be inferred. A multi-methodological approach is clearly called for in order to capture the full complexity of translation, and translation studies must be open to extend its curiosity beyond...... itself, into regions like cognitive psychology, psycho- and neurolinguistics, and neuroscience, where the interest in what goes on in our heads is also very strong....

  20. Microarrays—Current and Future Applications in Biomedical Research

    Directory of Open Access Journals (Sweden)

    Ulrich Certa

    2011-11-01

    Full Text Available Microarrays covers research where microarrays are applied to address complex biological questions. This new open access journal publishes articles where novel applications or state-of-the art technology developments in the field are reported. In addition, novel methods or data analysis algorithms are under the scope of Microarrays. This journal will serve as a platform for fast and efficient sharing of data within this large user community. As one of the first microarray users in Europe back in 1996, I am proud to serve as Editor-in-Chief and I believe we have assembled a highly proficient Editorial Board, responsible for a fair and fast peer-review of articles.

  1. Current Status of Japanese Global Precipitation Measurement (GPM) Research Project

    Science.gov (United States)

    Kachi, Misako; Oki, Riko; Kubota, Takuji; Masaki, Takeshi; Kida, Satoshi; Iguchi, Toshio; Nakamura, Kenji; Takayabu, Yukari N.

    2013-04-01

    The Global Precipitation Measurement (GPM) mission is a mission led by the Japan Aerospace Exploration Agency (JAXA) and the National Aeronautics and Space Administration (NASA) under collaboration with many international partners, who will provide constellation of satellites carrying microwave radiometer instruments. The GPM Core Observatory, which carries the Dual-frequency Precipitation Radar (DPR) developed by JAXA and the National Institute of Information and Communications Technology (NICT), and the GPM Microwave Imager (GMI) developed by NASA. The GPM Core Observatory is scheduled to be launched in early 2014. JAXA also provides the Global Change Observation Mission (GCOM) 1st - Water (GCOM-W1) named "SHIZUKU," as one of constellation satellites. The SHIZUKU satellite was launched in 18 May, 2012 from JAXA's Tanegashima Space Center, and public data release of the Advanced Microwave Scanning Radiometer 2 (AMSR2) on board the SHIZUKU satellite was planned that Level 1 products in January 2013, and Level 2 products including precipitation in May 2013. The Japanese GPM research project conducts scientific activities on algorithm development, ground validation, application research including production of research products. In addition, we promote collaboration studies in Japan and Asian countries, and public relations activities to extend potential users of satellite precipitation products. In pre-launch phase, most of our activities are focused on the algorithm development and the ground validation related to the algorithm development. As the GPM standard products, JAXA develops the DPR Level 1 algorithm, and the NASA-JAXA Joint Algorithm Team develops the DPR Level 2 and the DPR-GMI combined Level2 algorithms. JAXA also develops the Global Rainfall Map product as national product to distribute hourly and 0.1-degree horizontal resolution rainfall map. All standard algorithms including Japan-US joint algorithm will be reviewed by the Japan-US Joint

  2. Plasma medicine—current state of research and medical application

    Science.gov (United States)

    Weltmann, K.-D.; von Woedtke, Th

    2017-01-01

    Plasma medicine means the direct application of cold atmospheric plasma (CAP) on or in the human body for therapeutic purposes. Further, the field interacts strongly with results gained for biological decontamination. Experimental research as well as first practical application is realized using two basic principles of CAP sources: dielectric barrier discharges (DBD) and atmospheric pressure plasma jets (APPJ). Originating from the fundamental insights that the biological effects of CAP are most probably caused by changes of the liquid environment of cells, and are dominated by reactive oxygen and nitrogen species (ROS, RNS), basic mechanisms of biological plasma activity are identified. It was demonstrated that there is no increased risk of cold plasma application and, above all, there are no indications for genotoxic effects. The most important biological effects of cold atmospheric pressure plasma were identified: (1) inactivation of a broad spectrum of microorganisms including multidrug resistant ones; (2) stimulation of cell proliferation and tissue regeneration with lower plasma treatment intensity (treatment time); (3) inactivation of cells by initialization of programmed cell death (apoptosis) with higher plasma treatment intensity (treatment time). In recent years, the main focus of clinical applications was in the field of wound healing and treatment of infective skin diseases. First CAP sources are CE-certified as medical devices now which is the main precondition to start the introduction of plasma medicine into clinical reality. Plasma application in dentistry and, above all, CAP use for cancer treatment are becoming more and more important research fields in plasma medicine. A further in-depth knowledge of control and adaptation of plasma parameters and plasma geometries is needed to obtain suitable and reliable plasma sources for the different therapeutic indications and to open up new fields of medical application.

  3. First language transfer in second language writing: An examination of current research

    Directory of Open Access Journals (Sweden)

    Khaled Karim

    2013-01-01

    Full Text Available First language (L1 transfer has been a key issue in the field of applied linguistics, second language acquisition (SLA, and language pedagogy for almost a century. Its importance, however, has been re-evaluated several times within the last few decades. The aim of this paper is to examine current research that has investigated the role of L1 transfer in second language (L2 writing. The paper begins by discussing the different views of L1 transfer and how they have changed over time and then reviews some of the major studies that have examined the role of L1 transfer both as a learning tool and as a communicative strategy in L2 writing. The paper concludes with a number of suggestions for L2 writing instruction and future research.

  4. [Deep brain stimulation: a review on current research].

    Science.gov (United States)

    Conca, Andreas; Di Pauli, Jan; Hinterhuber, Hartmann; Kapfhammer, Hans-Peter

    2011-01-01

    Recently Deep brain stimulation (DBS) has found continuous use in treatment of neurological movement disorders. However DBS in psychiatric illnesses is less investigated. Its application in depression, obsessive-compulsive disorder, and therapy-resistant Tourette- Syndrome shows positive effects and offers an advanced alternative to neurosurgical therapies of the past. There are also case reports suggesting therapeutic benefits in schizophrenia and addiction. To a large extent, the mechanisms of action appear to be still unknown; the side effects seem partially modulated through the stimulation parameters. Furthermore, some ethics committees argue that DBS exhibits a relevant impact on the personality. The novel approach as well as the unknown long term effects of DBS implicate that the technique can be performed only under strict individual diagnosis and rigorous consideration of all ethical concerns.

  5. Research on Field Emission and Dark Current in ILC Cavities

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Kexin; Li, Yongming; Palczewski, Ari; Geng, Rongli

    2013-09-01

    Field emission and dark current are issues of concern for SRF cavity performance and SRF linac operation. Complete understanding and reliable control of the issue are still needed, especially in full-scale multi-cell cavities. Our work aims at developing a generic procedure for finding an active field emitter in a multi-cell cavity and benchmarking the procedure through cavity vertical test. Our ultimate goal is to provide feedback to cavity preparation and cavity string assembly in order to reduce or eliminate filed emission in SRF cavities. Systematic analysis of behaviors of field emitted electrons is obtained by ACE3P developed by SLAC. Experimental benchmark of the procedure was carried out in a 9-cell cavity vertical test at JLab. The energy spectrum of Bremsstrahlung X-rays is measured using a NaI(Tl) detector. The end-point energy in the X-ray energy spectrum is taken as the highest kinetic electron energy to predict longitudinal position of the active field emitter. Angular location of the field emitter is determined by an array of silicon diodes around irises of the cavity. High-resolution optical inspection was conducted at the predicted field emitter location.

  6. Current trends and future directions in flower development research.

    Science.gov (United States)

    Scutt, Charlie P; Vandenbussche, Michiel

    2014-11-01

    Flowers, the reproductive structures of the approximately 400 000 extant species of flowering plants, exist in a tremendous range of forms and sizes, mainly due to developmental differences involving the number, arrangement, size and form of the floral organs of which they consist. However, this tremendous diversity is underpinned by a surprisingly robust basic floral structure in which a central group of carpels forms on an axis of determinate growth, almost invariably surrounded by two successive zones containing stamens and perianth organs, respectively. Over the last 25 years, remarkable progress has been achieved in describing the molecular mechanisms that control almost all aspects of flower development, from the phase change that initiates flowering to the final production of fruits and seeds. However, this work has been performed almost exclusively in a small number of eudicot model species, chief among which is Arabidopsis thaliana. Studies of flower development must now be extended to a much wider phylogenetic range of flowering plants and, indeed, to their closest living relatives, the gymnosperms. Studies of further, more wide-ranging models should provide insights that, for various reasons, cannot be obtained by studying the major existing models alone. The use of further models should also help to explain how the first flowering plants evolved from an unknown, although presumably gymnosperm-like ancestor, and rapidly diversified to become the largest major plant group and to dominate the terrestrial flora. The benefits for society of a thorough understanding of flower development are self-evident, as human life depends to a large extent on flowering plants and on the fruits and seeds they produce. In this preface to the Special Issue, we introduce eleven articles on flower development, representing work in both established and further models, including gymnosperms. We also present some of our own views on current trends and future directions of the

  7. [Magnetoreception systems in birds: a review of current research].

    Science.gov (United States)

    Kishkinev, D A; Chernetsov, N S

    2014-01-01

    Currently at least two independent systems of magnetoreception are believed to exist in birds, based on different biophysical principles, located in different parts of their bodies, and having different innervation. One magnetoreceptory system is located in the retina and may be based on photo-induced biradical chemical reactions on the basis of cryptochrome. Information from these receptors is processed in a specialized part of visual Wulst, the so-called Cluster N. There are good reasons to believe that this visual magnetoreceptor processes compass magnetic information which is necessary for migratory orientation. The second magnetoreceptory system is probably iron-based (biogenic magnetite), is located somewhere in the upper beak (its exact location and ultrastructure of receptors remain unknown), and is innervated by the ophthalmic branch of trigeminal nerve. It cannot be ruled out that this system participates in spatial representation and helps forming either a kind of map or more primitive signposts, based on regular spatial variation of the geomagnetic field. The magnetic map probably governs navigation of migrating birds across hundreds and thousands of kilometers. Apart from these two systems whose existence may be considered to be convincingly shown (even if their details are not yet fully clear), there are data on the existence of magnetoreceptors based on the vestibular system. It cannot be ruled out that iron-based magnetoreception takes place in lagena (a structure homologous to cochlea of marsupials and eutherians), and the information perceived is processes in vestibular nuclei. The very existence of this magnetoreception system needs verification, and its function remains completely open.

  8. Nontyphoidal salmonella disease: Current status of vaccine research and development.

    Science.gov (United States)

    Tennant, Sharon M; MacLennan, Calman A; Simon, Raphael; Martin, Laura B; Khan, M Imran

    2016-06-01

    currently under development.

  9. Prebiotics and the health benefits of fiber: current regulatory status, future research, and goals.

    Science.gov (United States)

    Brownawell, Amy M; Caers, Wim; Gibson, Glenn R; Kendall, Cyril W C; Lewis, Kara D; Ringel, Yehuda; Slavin, Joanne L

    2012-05-01

    First defined in the mid-1990s, prebiotics, which alter the composition and activity of gastrointestinal (GI) microbiota to improve health and well-being, have generated scientific and consumer interest and regulatory debate. The Life Sciences Research Organization, Inc. (LSRO) held a workshop, Prebiotics and the Health Benefits of Fiber: Future Research and Goals, in February 2011 to assess the current state of the science and the international regulatory environment for prebiotics, identify research gaps, and create a strategy for future research. A developing body of evidence supports a role for prebiotics in reducing the risk and severity of GI infection and inflammation, including diarrhea, inflammatory bowel disease, and ulcerative colitis as well as bowel function disorders, including irritable bowel syndrome. Prebiotics also increase the bioavailability and uptake of minerals and data suggest that they reduce the risk of obesity by promoting satiety and weight loss. Additional research is needed to define the relationship between the consumption of different prebiotics and improvement of human health. New information derived from the characterization of the composition and function of different prebiotics as well as the interactions among and between gut microbiota and the human host would improve our understanding of the effects of prebiotics on health and disease and could assist in surmounting regulatory issues related to prebiotic use.

  10. Strongyloidiasis Current Status with Emphasis in Diagnosis and Drug Research

    Science.gov (United States)

    Minori, Karen

    2017-01-01

    Strongyloidiasis is a parasitic neglected disease caused by the nematode Strongyloides stercoralis affecting 30 to 100 million people worldwide. Complications, strongly associated with alcoholism, organ transplants, and HTLV-1 virus, often arise due to late diagnosis, frequently leading to patient death. Lack of preemptive diagnosis is not the only difficulty when dealing with this parasite, since there are no gold standard diagnostic techniques, and the ones used have problems associated with sensitivity, resulting in false negatives. Treatment is also an issue as ivermectin and benzimidazoles administration leads to inconsistent cure rates and several side effects. Researching new anti-Strongyloides drugs is a difficult task since S. stercoralis does not develop until the adult stages in Mus musculus (with the exception of SCID mice), the main experimental host model. Fortunately, alternative parasite models can be used, namely, Strongyloides ratti and S. venezuelensis. However, even with these models, there are other complications in finding new drugs, which are associated with specific in vitro assay protocol steps, such as larvae decontamination. In this review, we highlight the challenges associated with new drug search, the compounds tested, and a list of published in vitro assay methodologies. We also point out advances being made in strongyloidiasis diagnosis so far. PMID:28210503

  11. Microorganisms in metalworking fluids: Current issues in research and management

    Directory of Open Access Journals (Sweden)

    Elżbieta A. Trafny

    2013-02-01

    Full Text Available The microbial contamination of water miscible metalworking fl uids (MWFs is a serious problem in metal industry. A good maintenance of MWF re-circulation systems can extend the lifetime of coolants and ensure the quality of the tools produced. In MWFs, as in the other water-based environments, microorganisms usually live in the form of biofi lms, the communities of bacteria and fungi attached to the surface of sumps, metal parts and also to each other. Biofi lms exhibit very high resistance to biocides. The effect of biocides that are used as additives to MWFs to control the growth of the bacterial and fungal microbiomes (microorganisms characteristic to the individual coolant system have become the subject of research only in recent years. There are also only sparse reports on the impact of biocides on microorganisms growing in biofi lms in MWF installations. Fast growing mycobacteria are important members of these biofi lm communities. Their presence has recently been linked with the occurrence of cases of hypersensitivity pneumonitis, a serious respiratory disorder in the metal industry employees. The new, relatively fast and inexpensive techniques to assess the species diversity within MWF microbiomes and their population size should be developed in order to control the microorganisms’ proliferation in MWFs and to diminish the occupational exposure to harmful bioaerosols in metal industry.

  12. Vitamin K metabolism: current knowledge and future research.

    Science.gov (United States)

    Card, David J; Gorska, Renata; Cutler, Jacky; Harrington, Dominic J

    2014-08-01

    Vitamin K is an essential fat-soluble micronutrient that is required for the post-translational γ-carboxylation of specific glutamic acid residues in hepatic and extra-hepatic proteins involved in blood coagulation and preventing cartilage and vasculature calcification. In humans, sources of vitamin K are derived from plants as phylloquinone and bacteria as the menaquinones. Menadione is a synthetic product used as a pharmaceutical but also represents an intermediate in the tissue-specific conversion of vitamin K to menaquinone-4, which preferentially resides in tissues such as brain. Research into vitamin K metabolism is essential for the understanding of vitamin K biology in health and disease. Progress in this area, driven by knowledge of vitamin K and the availability of markers of vitamin K status, has already proved beneficial in many areas of medicine and further opportunities present themselves. Areas of interest discussed in this review include prophylactic administration of vitamin K1 in term and preterm neonates, interactions between vitamins K and E, the industrial conversion of vitamin K to dihydro-vitamin K in foods, tissue-specific conversion of vitamin K to menaquinone-4, the biological activity of the five and seven carbon metabolites of vitamin K and circadian variations.

  13. Current Challenges and Prospective Research for Upscaling Hybrid Perovskite Photovoltaics.

    Science.gov (United States)

    Williams, Spencer T; Rajagopal, Adharsh; Chueh, Chu-Chen; Jen, Alex K-Y

    2016-03-01

    Organic-inorganic hybrid perovskite photovoltaics (PSCs) are poised to push toward technology translation, but significant challenges complicating commercialization remain. Though J-V hysteresis and ecotoxicity are uniquely imposing issues at scale, CH3NH3PbI3 degradation is by far the sharpest limitation to the technology's potential market contribution. Herein, we offer a perspective on the practical market potential of PSCs, the nature of fundamental PSC challenges at scale, and an outline of prospective solutions for achieving module scale PSC production tailored to intrinsic advantages of CH3NH3PbI3. Although integrating PSCs into the energy grid is complicated by CH3NH3PbI3 degradation, the ability of PSCs to contribute to consumer electronics and other niche markets like those organic photovoltaics have sought footing in rests primarily upon the technology's price point. Thus, slot die, roll-to-roll processing has the greatest potential to enable PSC scale-up, and herein, we present a perspective on the research necessary to realize fully printable PSCs at scale.

  14. Strongyloidiasis Current Status with Emphasis in Diagnosis and Drug Research.

    Science.gov (United States)

    Mendes, Tiago; Minori, Karen; Ueta, Marlene; Miguel, Danilo Ciccone; Allegretti, Silmara Marques

    2017-01-01

    Strongyloidiasis is a parasitic neglected disease caused by the nematode Strongyloides stercoralis affecting 30 to 100 million people worldwide. Complications, strongly associated with alcoholism, organ transplants, and HTLV-1 virus, often arise due to late diagnosis, frequently leading to patient death. Lack of preemptive diagnosis is not the only difficulty when dealing with this parasite, since there are no gold standard diagnostic techniques, and the ones used have problems associated with sensitivity, resulting in false negatives. Treatment is also an issue as ivermectin and benzimidazoles administration leads to inconsistent cure rates and several side effects. Researching new anti-Strongyloides drugs is a difficult task since S. stercoralis does not develop until the adult stages in Mus musculus (with the exception of SCID mice), the main experimental host model. Fortunately, alternative parasite models can be used, namely, Strongyloides ratti and S. venezuelensis. However, even with these models, there are other complications in finding new drugs, which are associated with specific in vitro assay protocol steps, such as larvae decontamination. In this review, we highlight the challenges associated with new drug search, the compounds tested, and a list of published in vitro assay methodologies. We also point out advances being made in strongyloidiasis diagnosis so far.

  15. Strongyloidiasis Current Status with Emphasis in Diagnosis and Drug Research

    Directory of Open Access Journals (Sweden)

    Tiago Mendes

    2017-01-01

    Full Text Available Strongyloidiasis is a parasitic neglected disease caused by the nematode Strongyloides stercoralis affecting 30 to 100 million people worldwide. Complications, strongly associated with alcoholism, organ transplants, and HTLV-1 virus, often arise due to late diagnosis, frequently leading to patient death. Lack of preemptive diagnosis is not the only difficulty when dealing with this parasite, since there are no gold standard diagnostic techniques, and the ones used have problems associated with sensitivity, resulting in false negatives. Treatment is also an issue as ivermectin and benzimidazoles administration leads to inconsistent cure rates and several side effects. Researching new anti-Strongyloides drugs is a difficult task since S. stercoralis does not develop until the adult stages in Mus musculus (with the exception of SCID mice, the main experimental host model. Fortunately, alternative parasite models can be used, namely, Strongyloides ratti and S. venezuelensis. However, even with these models, there are other complications in finding new drugs, which are associated with specific in vitro assay protocol steps, such as larvae decontamination. In this review, we highlight the challenges associated with new drug search, the compounds tested, and a list of published in vitro assay methodologies. We also point out advances being made in strongyloidiasis diagnosis so far.

  16. Ovarian aging and menopause: current theories, hypotheses, and research models.

    Science.gov (United States)

    Wu, Julie M; Zelinski, Mary B; Ingram, Donald K; Ottinger, Mary Ann

    2005-12-01

    Aging of the reproductive system has been studied in numerous vertebrate species. Although there are wide variations in reproductive strategies and hormone cycle components, many of the fundamental changes that occur during aging are similar. Evolutionary hypotheses attempt to explain why menopause occurs, whereas cellular hypotheses attempt to explain how it occurs. It is commonly believed that a disruption in the hypothalamic-pituitary-gonadal axis is responsible for the onset of menopause. Data exist to demonstrate that the first signs of menopause occur at the level of the brain or the ovary. Thus, finding an appropriate and representative animal model is especially important for the advancement of menopause research. In primates, there is a gradual decline in the function of the hypothalamic-pituitary-gonadal (HPG) axis ultimately resulting in irregularities in menstrual cycles and increasingly sporadic incidence of ovulation. Rodents also exhibit a progressive deterioration in HPG axis function; however, they also experience a period of constant estrus accompanied by intermittent ovulations, reduced progesterone levels, and elevated circulating estradiol levels. It is remarkable to observe that females of other classes also demonstrate deterioration in HPG axis function and ovarian failure. Comparisons of aging in various taxa provide insight into fundamental biological mechanisms of aging that could underlie reproductive decline.

  17. Current progress in epigenetic research for hepato-carcinomagenesis

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Hepatocellular carcinoma is the main type of primary liver cancer,and also one of the most malignant tumors.At present,the pathogenesis mechanisms of liver cancer are not entirely clear.It has been shown that inactivation of tumor suppressor genes and activation of oncogenes play a significant role in carcinogenesis,caused by the genetic and epigenetic aberrance.In the past,people generally thought that genetic mutation is a key event of tumor pathogenesis,and somatic mutation of tumor suppressor genes is in particular closely associated with oncogenesis.With deeper understanding of tumors in recent years,increasing evidence has shown that epigenetic silencing of those genes,as a result of aberrant hypermethylation of CpG islands in promoters and histone modification,is essential to carcinogenesis and metastasis.The term epigenetics refers to heritable changes in gene expression caused by regulation mechanisms,other than changes in the underlying DNA sequence.Specific epigenetic processes include DNA methylation,genome imprinting,chromotin remodeling,histone modification and microRNA regulations.This paper reviews recent epigenetics research progress in the hepatocellular carcinoma study,and tries to depict the relationships between hepatocellular carcinomagenesis and DNA methylation as well as microRNA regulation.

  18. Current progress in epigenetic research for hepato-carcinomagenesis

    Institute of Scientific and Technical Information of China (English)

    HUANG Jian

    2009-01-01

    Hepatocellular carcinoma is the main type of primary liver cancer, and also one of the most malignant tumors. At present, the pathogenesis mechanisms of liver cancer are not entirely clear. It has been shown that inactivation of tumor suppressor genes and activation of oncogenes play a significant role in carcinogenesis, caused by the genetic and epigenetic aberrance. In the past, people generally thought that genetic mutation is a key event of tumor pathogenesis, and somatic mutation of tumor suppressor genes is in particular closely associated with oncogenesis. With deeper understanding of tumors in recent years, increasing evidence has shown that epigenetic silencing of those genes, as a result of aberrant hypermethylation of CpG islands in promoters and histone modification, is essential to carcinogenesis and metastasis. The term epigenetics refers to heritable changes in gene expression caused by regulation mechanisms, other than changes in the underlying DNA sequence. Specific epi-genetic processes include DNA methylation, genome imprinting, chromotin remodeling, histone modi-fication and microRNA regulations. This paper reviews recent epigenetics research progress in the hepatocellular carcinoma study, and tries to depict the relationships between hepatocellular carci-nomagenesis and DNA methylation as well as microRNA regulation.

  19. Dairy products on metabolic health: current research and clinical implications.

    Science.gov (United States)

    Da Silva, Marine S; Rudkowska, Iwona

    2014-03-01

    Dairy products have been thought to have a beneficial role in the metabolic syndrome (MetS). MetS constitutes a cluster of risk factors for an increased mortality, including obesity, impaired glucose homeostasis, hypertension and atherogenic dyslipidemia. Individuals with MetS are also often in a chronic, low-grade inflammatory state. The objective of this review is to examine recent meta-analyses and clinical studies on the association between dairy products consumption and these MetS risk factors. Findings from studies demonstrate that weight loss related to dairy product intake is due to the combination of an energy-restricted diet with consumption of dairy products. Further, a limited number of studies have shown beneficial effects of dairy consumption on plasma lipids, blood pressure, glucose homeostasis or inflammatory and oxidative stress profiles. Overall, this review article suggests that adults should consume at least 2-3 servings of dairy products per day within a well-balanced diet and a healthy lifestyle for metabolic health. Yet, higher dairy product consumption may have additional beneficial effects, but more well-designed intervention studies are needed to ascertain these effects.

  20. Soil Contamination and Remediation Strategies. Current research and future challenge

    Science.gov (United States)

    Petruzzelli, G.

    2012-04-01

    eliminating the source of pollution, but also on blocking the pathways from contaminants to receptors or reducing the exposure to contaminants,. Future challenge integration of sustainability into remediation decision-making. Soil is not a waste! There is a growing interest in the clean up approaches that maintain soil quality after remediation treatments. This issue is of great importance in the U.S.A. where the EPA from 2009 is promoting innovative clean-up strategies (Green Remediation). Green remediation is defined as the practice of considering all environmental effects of remedy and incorporating options to maximize environmental benefit of cleanup actions . These remediation strategies restore contaminated sites to productive use with a great attention to the global environmental quality, including the preservation of soil functionality according to the following principles: use minimally invasive technologies; use passive energy technologies such as bioremediation and phytoremediation as primary remedies or finishing steps where possible and effective; minimize soil and habitat disturbance; minimize bioavailability of contaminants trough adequate contaminant source and plume control If we move from the current definition of remedial targets based on total concentrations, technologies with low impact on the environment can be utilized reducing the wrong choice to disposal soil in landfill destroying quickly a not renewable essential resource.

  1. Current knowledge on the genetics of autism and propositions for future research.

    Science.gov (United States)

    Bourgeron, Thomas

    2016-01-01

    Autism spectrum disorders (ASD) are a heterogeneous group of neuropsychiatric disorders characterized by problems in social communication, as well as by the presence of restricted interests, stereotyped and repetitive behaviours. In the last 40years, genetic studies have provided crucial information on the causes of ASD and its diversity. In this article, I will first review the current knowledge on the genetics of ASD and then suggest three propositions to foster research in this field. Twin and familial studies estimated the heritability of ASD to be 50%. While most of the inherited part of ASD is captured by common variants, our current knowledge on the genetics of ASD comes almost exclusively from the identification of highly penetrant de novo mutations through candidate gene or whole exome/genome sequencing studies. Approximately 10% of patients with ASD, especially those with intellectual disability, are carriers of de novo copy-number (CNV) or single nucleotide variants (SNV) affecting clinically relevant genes for ASD. Given the function of these genes, it was hypothesized that abnormal synaptic plasticity and failure of neuronal/synaptic homeostasis could increase the risk of ASD. In addition to these discoveries, three propositions coming from institutions, researchers and/or communities of patients and families can be made to foster research on ASD: (i) to use more dimensional and quantitative data than diagnostic categories; (ii) to increase data sharing and research on genetic and brain diversity in human populations; (iii) to involve patients and relatives as participants for research. Hopefully, this knowledge will lead to a better diagnosis, care and integration of individuals with ASD.

  2. The Current State of Research on Networks in China’s Business System

    NARCIS (Netherlands)

    J. Meuer (Johannes); B. Krug (Barbara)

    2009-01-01

    textabstractThe purpose of the paper is to assess the current state of network research in China’s business system. Research on networks has developed significantly during the last decades in regards to analytic techniques, number of research projects, and accumulated findings. While research on net

  3. The Current State of Research on Networks in China’s Business System

    NARCIS (Netherlands)

    J. Meuer (Johannes); B. Krug (Barbara)

    2009-01-01

    textabstractThe purpose of the paper is to assess the current state of network research in China’s business system. Research on networks has developed significantly during the last decades in regards to analytic techniques, number of research projects, and accumulated findings. While research on net

  4. Current Situation and Suggestions for Development of Recycling Agriculture in Lingwu Municipality%灵武市循环农业发展现状及建议

    Institute of Scientific and Technical Information of China (English)

    张仲军; 杨金贵; 俞宏彪

    2015-01-01

    The combination of agriculture with animal husbandry as well as planting with livestock raising is a kind of recy-cling agriculture. Based on an investigation on the current situation of the combination of agriculture with animal husbandry as well as planting with livestock raising in Lingwu Municipality, an exploration is made on the development of recycling a-griculture, organic agriculture and the new ways for supporting animal husbandry with agriculture and promoting agriculture with animal husbandry.%农牧种养结合是循环农业的一种形式,通过对灵武市农牧种养结合现状调研,探索发展循环农业、有机农业、以"农养牧,以牧促农"的新路子.

  5. 耕地保护生态补偿现状及政策建议%Current Situation and Policy Suggestion of Ecological Compensation for Cultivated Land Protection

    Institute of Scientific and Technical Information of China (English)

    李林; 李海燕

    2015-01-01

    On the basis of exploration of the present situation of cultivated land protection of ecological compensation in China,the necessity to establish the ecological compensation of cultivated land protection was analyzed,and relevant policy suggestions to perfect the ecological compensation for farmland protection in China were finally put forward.%在剖析我国耕地保护生态补偿现状的基础上,分析建立耕地保护生态补偿的必要性,最后提出完善我国耕地保护生态补偿的相关政策建议。

  6. Current Status of Food Safety System in China and Suggestions%我国食品安全体系现状及建议

    Institute of Scientific and Technical Information of China (English)

    段云

    2011-01-01

    从食品安全战略、食品安全组织、食品安全法律法规、我国食品安全领域存在的问题和建议等方面综述我国食品安全体系。%Food safety plays important role in our life.Recently,there occur several incidents in food safety,which was noticed by our government.This paper mainly reviewed the food safety strategies,organizations,laws and regulations,problems and suggestions for the problems.

  7. Wi-Fi and health: review of current status of research.

    Science.gov (United States)

    Foster, Kenneth R; Moulder, John E

    2013-12-01

    This review summarizes the current state of research on possible health effects of Wi-Fi (a commercial name for IEEE 802.11-compliant wireless networking). In response to public concerns about health effects of Wi-Fi and wireless networks and calls by government agencies for research on possible health and safety issues with the technology, a considerable amount of technology-specific research has been completed. A series of high quality engineering studies have provided a good, but not complete, understanding of the levels of radiofrequency (RF) exposure to individuals from Wi-Fi. The limited number of technology-specific bioeffects studies done to date are very mixed in terms of quality and outcome. Unequivocally, the RF exposures from Wi-Fi and wireless networks are far below U.S. and international exposure limits for RF energy. While several studies report biological effects due to Wi-Fi-type exposures, technical limitations prevent drawing conclusions from them about possible health risks of the technology. The review concludes with suggestions for future research on the topic.

  8. Payment of research participants: current practice and policies of Irish research ethics committees.

    LENUS (Irish Health Repository)

    Roche, Eric

    2013-09-01

    Payment of research participants helps to increase recruitment for research studies, but can pose ethical dilemmas. Research ethics committees (RECs) have a centrally important role in guiding this practice, but standardisation of the ethical approval process in Ireland is lacking.

  9. 中国天然橡胶产业现状及其发展建议%Current Situation of Chinese Natural Rubber Industry and Development Suggestions

    Institute of Scientific and Technical Information of China (English)

    祁栋灵; 王秀全; 张志扬; 黄月球

    2013-01-01

    This paper analyzes general situation of development in Chinese natural rubber industry, the industrial status and role of Chinese natural rubber industry, as well as establish production impetus of Chinese rubber science & technology to rubber production, and putting forward some suggestions on how to improve Chinese natural rubber industry.%从我国天然橡胶产业发展概况、产业的地位和作用,以及我国橡胶科技对植胶生产的推动作用等方面对中国天然橡胶产业发展现状进行了综述,并提出了促进我国天然橡胶产业发展提升的建议.

  10. Current and Future Research in Active Control of Lightweight, Flexible Structures Using the X-56 Aircraft

    Science.gov (United States)

    Ryan, John J.; Bosworth, John T.; Burken, John J.; Suh, Peter M.

    2014-01-01

    The X-56 Multi-Utility Technology Testbed aircraft system is a versatile experimental research flight platform. The system was primarily designed to investigate active control of lightweight flexible structures, but is reconfigurable and capable of hosting a wide breadth of research. Current research includes flight experimentation of a Lockheed Martin designed active control flutter suppression system. Future research plans continue experimentation with alternative control systems, explore the use of novel sensor systems, and experiments with the use of novel control effectors. This paper describes the aircraft system, current research efforts designed around the system, and future planned research efforts that will be hosted on the aircraft system.

  11. Book Review: Current Issues in International Human Resource Management and Strategy Research

    DEFF Research Database (Denmark)

    Gretzinger, Susanne

    2009-01-01

    The article reviews the book "Current Issues in International Human Resource Management and Strategy Research," edited by Marion Festing and Susanne Royer.......The article reviews the book "Current Issues in International Human Resource Management and Strategy Research," edited by Marion Festing and Susanne Royer....

  12. Book Review: Current Issues in International Human Resource Management and Strategy Research

    DEFF Research Database (Denmark)

    Gretzinger, Susanne

    2009-01-01

    The article reviews the book "Current Issues in International Human Resource Management and Strategy Research," edited by Marion Festing and Susanne Royer.......The article reviews the book "Current Issues in International Human Resource Management and Strategy Research," edited by Marion Festing and Susanne Royer....

  13. A Sustainable Model for Integrating Current Topics in Machine Learning Research into the Undergraduate Curriculum

    Science.gov (United States)

    Georgiopoulos, M.; DeMara, R. F.; Gonzalez, A. J.; Wu, A. S.; Mollaghasemi, M.; Gelenbe, E.; Kysilka, M.; Secretan, J.; Sharma, C. A.; Alnsour, A. J.

    2009-01-01

    This paper presents an integrated research and teaching model that has resulted from an NSF-funded effort to introduce results of current Machine Learning research into the engineering and computer science curriculum at the University of Central Florida (UCF). While in-depth exposure to current topics in Machine Learning has traditionally occurred…

  14. A Sustainable Model for Integrating Current Topics in Machine Learning Research into the Undergraduate Curriculum

    Science.gov (United States)

    Georgiopoulos, M.; DeMara, R. F.; Gonzalez, A. J.; Wu, A. S.; Mollaghasemi, M.; Gelenbe, E.; Kysilka, M.; Secretan, J.; Sharma, C. A.; Alnsour, A. J.

    2009-01-01

    This paper presents an integrated research and teaching model that has resulted from an NSF-funded effort to introduce results of current Machine Learning research into the engineering and computer science curriculum at the University of Central Florida (UCF). While in-depth exposure to current topics in Machine Learning has traditionally occurred…

  15. Current situation and suggestions for pressure ulcer management in China%我国压疮管理现状与建议

    Institute of Scientific and Technical Information of China (English)

    张洪君; 卢㛃; 刘金莲

    2014-01-01

    Pressure ulcer is a common and important complication in clinical nursing. Its mechanism is complicated. Pressure ulcer widely exists in different departments of hospital and would greatly inlfuence patients. This paper summarized and analyzed the current situation of pressure ulcer management in China. The ideas and methods of pressure ulcer management from abroad had been applied in some medical institutions in China, and were modiifed in order to ift themselves. But due to the diversity of our medical institutions, we still need to formulate a uniifed nursing standard to improve the prevention and treatment management of pressure ulcer in our country.%压疮是临床护理工作中常见的重要并发症,其发生机制复杂,广泛存在于各科室,给患者带来较大影响。本文通过对目前我国压疮管理现状的分析发现,国际压疮护理管理理念和方法已经在我国部分医疗机构得到改进和应用,逐步形成适合我国的压疮防治规范。但是,由于我国各地医疗机构水平参差不齐,为提高全国整体压疮预防与治疗管理水平,还须制订统一的全国压疮护理标准。

  16. Current Research.

    Science.gov (United States)

    Hunt, Mary Alice

    1981-01-01

    Describes a doctoral dissertation entitled "World-Future Images in Childrens Literature" which analyzed books on science fiction or utopian fiction by 43 authors of children's literature to determine whether presentations were optimistic or pessimistic. Results indicating generally optimistic stories are discussed, as well as strengths and…

  17. Technical support to the Solvent Refined Coal (SRC) demonstration projects: assessment of current research and development

    Energy Technology Data Exchange (ETDEWEB)

    Edwards, M.S.; Rodgers, B.R.; Brown, C.H.; Carlson, P.K.; Gambill, W.R.; Gilliam, T.M.; Holmes, J.M.; Krishnan, R.P.; Parsly, L.F.

    1980-12-01

    A program to demonstrate Solvent Refined Coal (SRC) technology has been initiated by the US Department of Energy (DOE) in partnership with two industrial groups. Project management responsibility has been assigned to the Oak Ridge Operations Office (ORO) of DOE. ORO requested that the Oak Ridge National Laboratory assess current research and development (R and D) activities and develop recommendations for those activities that might contribute to successful completion of the SRC demonstration plant projects. The objectives of this final report are to discuss in detail the problem areas in SRC; to discuss the current and planned R and D investigations relevant to the problems identified; and to suggest appropriate R and D activities in support of designs for the SRC demonstration plants. Four types of R and D activities are suggested: continuation of present and planned activities; coordination of activities and results, present and proposed; extension/redirection of activities not involving major equipment purchase or modifications; and new activities. Important examples of the first type of activity include continuation of fired heater, slurry rheology, and slurry mixing studies at Ft. Lewis. Among the second type of activity, coordination of data acquisition and interpretation is recommended in the areas of heat transfer, vapor/liquid equilibria, and physical properties. Principal examples of recommendations for extension/redirection include screening studies at laboratory scale on the use of carbonaceous precoat (e.g., anthracite) infiltration, and 15- to 30-day continuous tests of the Texaco gasifier at the Texaco Montebello facility (using SRC residues).

  18. Physiologically based pharmacokinetic modeling of human exposure to perfluorooctanoic acid suggests historical non drinking-water exposures are important for predicting current serum concentrations.

    Science.gov (United States)

    Worley, Rachel Rogers; Yang, Xiaoxia; Fisher, Jeffrey

    2017-09-01

    Manufacturing of perfluorooctanoic acid (PFOA), a synthetic chemical with a long half-life in humans, peaked between 1970 and 2002, and has since diminished. In the United States, PFOA is detected in the blood of >99% of people tested, but serum concentrations have decreased since 1999. Much is known about exposure to PFOA in drinking water; however, the impact of non-drinking water PFOA exposure on serum PFOA concentrations is not well characterized. The objective of this research is to apply physiologically based pharmacokinetic (PBPK) modeling and Monte Carlo analysis to evaluate the impact of historic non-drinking water PFOA exposure on serum PFOA concentrations. In vitro to in vivo extrapolation was utilized to inform descriptions of PFOA transport in the kidney. Monte Carlo simulations were incorporated to evaluate factors that account for the large inter-individual variability of serum PFOA concentrations measured in individuals from North Alabama in 2010 and 2016, and the Mid-Ohio River Valley between 2005 and 2008. Predicted serum PFOA concentrations were within two-fold of experimental data. With incorporation of Monte Carlo simulations, the model successfully tracked the large variability of serum PFOA concentrations measured in populations from the Mid-Ohio River Valley. Simulation of exposure in a population of 45 adults from North Alabama successfully predicted 98% of individual serum PFOA concentrations measured in 2010 and 2016, respectively, when non-drinking water ingestion of PFOA exposure was included. Variation in serum PFOA concentrations may be due to inter-individual variability in the disposition of PFOA and potentially elevated historical non-drinking water exposures. Published by Elsevier Inc.

  19. Current situation and Suggestions About Overseas Investment of Suzhou enterprises%苏州企业境外投资现状及发展建议

    Institute of Scientific and Technical Information of China (English)

    姚晴霞

    2013-01-01

    Suzhou in attracting foreign investment has made remarkable achievements,but with respect to overseas investment,it is still in the initial stage.Suzhou enterprises’overseas investment has dominant force private enterprises,investment diversification and expanding . The main difficulty faced by overseas investment is not familiar with the investment policy and legal environment ,government support policies unsound,the lack of international management talent and financing difficulties,and finally put forward suggestion.%苏州在吸引国际资本方面取得了令人瞩目的成绩,但苏州的境外投资相对于利用外资来说,还处于起步阶段。苏州企业境外投资呈现民营企业是投资主导力量、境外投资方式多元化和投资规模不断扩大的特点。企业开展境外投资面临的困难和问题是企业对境外投资政策和法律环境的不熟悉、政府境外投资支持政策和服务体系不健全、国际化经营人才缺乏和融资难四个方面,最后针对性地提出促进苏州企业境外投资的建议。

  20. 我国玉米品种权保护现状及建设%Current Situation and Suggestions on the Protection of Maize Variety Rights in China

    Institute of Scientific and Technical Information of China (English)

    2013-01-01

    In order to strengthen the protection of maize new variety rightsm ,standardize seed market ,ensure food security ,the protection present situation of maize variety rights in China was discussed ,the existing prob-lems were analysed such as the too long period of the review ,the delay of economic transformation of author-ized varieties ,the seriousness of infringing upon variety rights and the difficulty of safeguarding the variety rights ,the improvement suggestions of maize variety rights in China were put forward .The protection strategy of variety rightsm were proposed ,including building up the system of approv combining between approbation and protection ,standardizing the trading platform of variety rightsm ,strengthen the peralties for infringement , encouraging the cooperation between school and enterprise ,speeding up the pace of achievement transformation%  为了加强玉米新品种权的保护,规范种子市场,确保粮食安全,阐述了我国玉米品种权保护的现状,分析了玉米品种权存在审查周期过长、授权品种经济转化滞后、侵权严重和维权艰难等问题,提出了应建立品种审定和保护相结合的体制、规范的品种权交易平台、加大对侵权的惩处力度、鼓励院企业作加速成果转化步伐等品种权保护策略。

  1. Effects of micro- and nanoplastics on aquatic ecosystems: Current research trends and perspectives.

    Science.gov (United States)

    Chae, Yooeun; An, Youn-Joo

    2017-02-17

    Contamination by bulk plastics and plastic debris is currently the one of the most serious environmental problems in aquatic ecosystems. In particular, small-scale plastic debris such as microplastics and nanoplastics has become leading contributors to the pollution of marine and freshwater ecosystems. Studies are investigating the impacts of micro-and nanoplastics on aquatic organisms and ecosystems worldwide. This review covers 83 studies that investigated the distribution of microplastics and the ecotoxicity of micro- and nanoplastics in marine and freshwater ecosystems. The studies indicated that micro-sized plastics and plastic debris were distributed at various concentrations in aquatic ecosystems around the world. They had various effects on the growth, development, behavior, reproduction, and mortality of aquatic animals. We discuss these studies in detail and suggest directions for future research.

  2. Hypnosis, suggestion, and suggestibility: an integrative model.

    Science.gov (United States)

    Lynn, Steven Jay; Laurence, Jean-Roch; Kirsch, Irving

    2015-01-01

    This article elucidates an integrative model of hypnosis that integrates social, cultural, cognitive, and neurophysiological variables at play both in and out of hypnosis and considers their dynamic interaction as determinants of the multifaceted experience of hypnosis. The roles of these variables are examined in the induction and suggestion stages of hypnosis, including how they are related to the experience of involuntariness, one of the hallmarks of hypnosis. It is suggested that studies of the modification of hypnotic suggestibility; cognitive flexibility; response sets and expectancies; the default-mode network; and the search for the neurophysiological correlates of hypnosis, more broadly, in conjunction with research on social psychological variables, hold much promise to further understanding of hypnosis.

  3. Current Practice in Measuring the Quality of Conceptual Models:Challenges and Research%Current Practice in Measuring the Quality of Conceptual Models:Challenges and Research

    Institute of Scientific and Technical Information of China (English)

    LIU Lei; WU Yu-feng; LI Xiao-jun

    2012-01-01

    How to measure the quality of conceptual models is an important issue in the IS field and related research. This paper conducts a review of research in measuring conceptual model quality and identifies the major theoretical and practical issues that need to be addressed in future studies. We review current classification frameworks for conceptual model quality and practice of measuring conceptual model quality. Based on the review, challenges for studies of measuring the quality of conceptual models are proposed and these challenges are also research points which should be strengthened in future studies.

  4. Navigation Hydraulics Research Program: Evaluation of Nanjing Hydraulic Research Institute Physical Model Current Meter.

    Science.gov (United States)

    1990-07-01

    readout circuit CURRENT VELOCITY / DIRECTION SENSOR A mini-servomotor and a piece of fibre optic rod are installed at the base. The rod is turned by...34Description. of The Fibre - Optic Type Miniature Propetler Velocity Meter" for detal Is) THE OPERATION OF THE COMBINED CURRENT VELOCITY ’ DIRECTION METER 1. Plug...of The Fibre - Optic Type Miniature propeller Velocity Meter" for details. Front Panel: Ma /jj (tPj ) Current Direction Readout (Degree) Sensitivity

  5. Reviewing current knowledge in snatch performance and technique: the need for future directions in applied research.

    Science.gov (United States)

    Ho, Lester K W; Lorenzen, Christian; Wilson, Cameron J; Saunders, John E; Williams, Morgan D

    2014-02-01

    This is a review of current research trends in weightlifting literature relating to the understanding of technique and its role in successful snatch performance. Reference to the world records in the snatch from the 1960s onwards indicates little progress across all weight categories. With such mediocre advances in performance at the International level, there is a need to better understand how snatch technique can improve performance even if only by a small margin. Methods of data acquisition for technical analysis of the snatch have involved mostly 2-dimensional barbell and joint kinematics. Although key variables which play a role in the successful outcome of a snatch lift have been heavily investigated, few studies have combined variables relating both the barbell and the weightlifter in their analyses. This suggests the need for a more detailed approach integrating both barbell-related and weightlifter-related data to enhance understanding of the mechanics of a successful lift. Currently, with the aid of technical advances in motion analysis, data acquisition, and methods of analysis, a more accurate representation of the movement can be provided. Better ways of understanding the key characteristics of technique in the snatch could provide the opportunity for more effective individualized feedback from the coach to the athlete, which should in turn lead to improved performance in competition.

  6. Crash data quality for road safety research: Current state and future directions.

    Science.gov (United States)

    Imprialou, Marianna; Quddus, Mohammed

    2017-03-02

    Crash databases are one of the primary data sources for road safety research. Therefore, their quality is fundamental for the accuracy of crash analyses and, consequently the design of effective countermeasures. Although crash data often suffer from correctness and completeness issues, these are rarely discussed or addressed in crash analyses. Crash reports aim to answer the five "W" questions (i.e. When?, Where?, What?, Who? and Why?) of each crash by including a range of attributes. This paper reviews current literature on the state of crash data quality for each of these questions separately. The most serious data quality issues appear to be: inaccuracies in crash location and time, difficulties in data linkage (e.g. with traffic data) due to inconsistencies in databases, severity misclassification, inaccuracies and incompleteness of involved users' demographics and inaccurate identification of crash contributory factors. It is shown that the extent and the severity of data quality issues are not equal between attributes and the level of impact in road safety analyses is not yet entirely known. This paper highlights areas that require further research and provides some suggestions for the development of intelligent crash reporting systems.

  7. Delivering patient decision aids on the Internet: definitions, theories, current evidence, and emerging research areas.

    Science.gov (United States)

    Hoffman, Aubri S; Volk, Robert J; Saarimaki, Anton; Stirling, Christine; Li, Linda C; Härter, Martin; Kamath, Geetanjali R; Llewellyn-Thomas, Hilary

    2013-01-01

    In 2005, the International Patient Decision Aids Standards Collaboration identified twelve quality dimensions to guide assessment of patient decision aids. One dimension-the delivery of patient decision aids on the Internet-is relevant when the Internet is used to provide some or all components of a patient decision aid. Building on the original background chapter, this paper provides an updated definition for this dimension, outlines a theoretical rationale, describes current evidence, and discusses emerging research areas. An international, multidisciplinary panel of authors examined the relevant theoretical literature and empirical evidence through 2012. The updated definition distinguishes Internet-delivery of patient decision aids from online health information and clinical practice guidelines. Theories in cognitive psychology, decision psychology, communication, and education support the value of Internet features for providing interactive information and deliberative support. Dissemination and implementation theories support Internet-delivery for providing the right information (rapidly updated), to the right person (tailored), at the right time (the appropriate point in the decision making process). Additional efforts are needed to integrate the theoretical rationale and empirical evidence from health technology perspectives, such as consumer health informatics, user experience design, and human-computer interaction. As of 2012, the updated theoretical rationale and emerging evidence suggest potential benefits to delivering patient decision aids on the Internet. However, additional research is needed to identify best practices and quality metrics for Internet-based development, evaluation, and dissemination, particularly in the areas of interactivity, multimedia components, socially-generated information, and implementation strategies.

  8. 大学英语ESP教学现状及发展建议%On the Current Teaching Condition of ESP Learning in the College English and Developing Suggestions

    Institute of Scientific and Technical Information of China (English)

    李然; 谢威

    2014-01-01

    改革开放使我国对外交流活动越来越丰富,与世界各国的频繁接触,使得各行各业急需许多既懂专业又懂英语的毕业生。因此专门用途英语ESP(English for specific purpose)成为了近年来研究的热点。本文论述了在高等院校进行英语ESP教学的现状以及相关的发展建议。%China’s reform and opening enriches its foreign exchange activities, and contacts with other countries frequently, resulting in all kinds of graduates who need to know professional knowledge and English knowledge. This makes ESP (English for specific purposes) a research highlight in recent years. This article talks about the current teaching condition of ESP learning in the college English and its developing suggestions.

  9. A Review of Research on Metacognition in Science Education: Current and Future Directions

    Science.gov (United States)

    Zohar, Anat; Barzilai, Sarit

    2013-01-01

    The goal of this study is to map the current state of research in the field of metacognition in science education, to identify key trends, and to discern areas and questions for future research. We conducted a systematic analysis of 178 studies published in peer-reviewed journals in the years 2000-2012 and indexed in the ERIC database. The…

  10. Research of resisting of the biological active point for constant and alternative current

    Directory of Open Access Journals (Sweden)

    S. N. Peregudov

    2008-05-01

    Full Text Available Is conducted research of resistance of biologically active point (BAT on a direct and variable current. Research results are presented. The estimation of intercommunication between resistance of skin and by an electromagnetic radiation in BAT is done. Is shown possibility of the use of experimental information for diagnostics of the state of human to the organism.

  11. Mindfulness for Children in Public Schools: Current Research and Developmental Issues to Consider

    Science.gov (United States)

    Chadwick, Jeanne; Gelbar, Nicholas W.

    2016-01-01

    Mindfulness-based interventions have increased in popularity over the past decade and interest continues to increase in the potential to use mindfulness-based interventions in schools. The current research concerning school-based mindfulness-based interventions is reviewed in this article. This research base is fragmented, as most of the studies…

  12. A Review of Research on Metacognition in Science Education: Current and Future Directions

    Science.gov (United States)

    Zohar, Anat; Barzilai, Sarit

    2013-01-01

    The goal of this study is to map the current state of research in the field of metacognition in science education, to identify key trends, and to discern areas and questions for future research. We conducted a systematic analysis of 178 studies published in peer-reviewed journals in the years 2000-2012 and indexed in the ERIC database. The…

  13. Current research trends and perspectives on materials-based hydrogen storage solutions: A critical review

    CSIR Research Space (South Africa)

    Ren, Jianwei

    2016-01-01

    Full Text Available Effective hydrogen storage solutions have been pursued for decades, and materials-based hydrogen storage is a research frontier of much current interest. Yet, no researched materials to date have come close to the DOE 2020 targets for hydrogen...

  14. The Focus of Current HCI Research in Usability Evaluation and Feedback

    DEFF Research Database (Denmark)

    Høegh, Rune Thaarup

    2007-01-01

    This paper presents the findings from a systematic literature study of the research on usability evaluation and feedback. The literature study covers the papers published from five key human-computer interaction journals for a period of four years, and depicts the most current research within...

  15. Current Research Activities in Drive System Technology in Support of the NASA Rotorcraft Program

    Science.gov (United States)

    Handschuh, Robert F.; Zakrajsek, James J.

    2006-01-01

    Drive system technology is a key area for improving rotorcraft performance, noise/vibration reduction, and reducing operational and manufacturing costs. An overview of current research areas that support the NASA Rotorcraft Program will be provided. Work in drive system technology is mainly focused within three research areas: advanced components, thermal behavior/emergency lubrication system operation, and diagnostics/prognostics (also known as Health and Usage Monitoring Systems (HUMS)). Current research activities in each of these activities will be presented. Also, an overview of the conceptual drive system requirements and possible arrangements for the Heavy Lift Rotorcraft program will be reviewed.

  16. [Resource activation in clinical psychology and psychotherapy: review of theoretical issues and current research].

    Science.gov (United States)

    Groß, L J; Stemmler, M; de Zwaan, M

    2012-08-01

    This review summarises theoretical issues and current research on working with clients' resources and strengths in clinical psychology and psychotherapy. Resource activation is considered as an important common factor in psychotherapy. In general, resource activation means an explicit focus on resources, strengths and potentials of the clients. After defining the term resources, considerations with regard to therapeutic attitude, principles of resource activation, approaches to resource diagnostics and different research strategies are presented. Current research focuses especially on the relation between resource activation and process variables in out-patient treatment.

  17. INSTITUTIONALISM AND INFORMATION SYSTEMS: CURRENT STATE OF THE ART AND POSITION OF FRENCH RESEARCH

    Directory of Open Access Journals (Sweden)

    Rolande Marciniak

    2009-10-01

    Full Text Available The various currents of institutionalism are used in management science, particularly in the area of information systems. Richard Scott's global model is a fertile framework for the analysis of institutional research. First, we will study the contributions of French research to institutionalism. Then, returning to the fundamentals of information systems (IS, we will show that the interaction between institutions and IS can be analysed via the notion of formal and informal rules. Research carried out at the University of Paris

  18. Reprioritizing current research trends in medical education: a reflection on research activities in Saudi Arabia.

    Science.gov (United States)

    Obeidat, Akef S; Alhaqwi, Ali Ibrahim; Abdulghani, Hamza Mohammad

    2015-04-01

    There are numerous national efforts to determine and develop research priorities of medical education in Saudi Arabia. These priorities were first proposed in 2010 by "Dr Al-Khuli's Chair for Developing Medical Education in Saudi Arabia". The proposed priority domains were: curriculum, students, faculty, and quality assurance and accreditation. To investigate publications in medical education at the national and international levels in areas relating to these proposed priorities. Electronic search within PubMed database for papers relating to each domain of priority was conducted at national and international levels in the last three years, using the same keywords as the priority domains, but only confined to undergraduate medical education. Out of 3145 articles retrieved when searching with keyword as broad as "undergraduate medical curriculum" only 81 articles worldwide and 3 articles from Saudi Arabia were dealing with curriculum related issues as a whole. Further search on the sub-domains "effective strategies to manage undergraduate curriculum" and "undergraduate medical education models", resulted in the retrieval of few articles worldwide and none from Saudi Arabia. At the national level, there were 63 publications from Saudi Arabia that were either course (topic)-specific or could not be classified under the four domains specified by Dr Al-Khuli's Chair. Research activities in medical education in Saudi Arabia in the last 3 years showed diversity and lack of focus in the research priorities. Efforts of academic and research centers should continue to monitor and encourage these activities toward achieving the recommended priorities.

  19. Current and Planned Cochlear Implant Research at New York University Laboratory for Translational Auditory Research

    Science.gov (United States)

    Svirsky, Mario A.; Fitzgerald, Matthew B.; Neuman, Arlene; Sagi, Elad; Tan, Chin-Tuan; Ketten, Darlene; Martin, Brett

    2013-01-01

    The Laboratory of Translational Auditory Research (LTAR/NYUSM) is part of the Department of Otolaryngology at the New York University School of Medicine and has close ties to the New York University Cochlear Implant Center. LTAR investigators have expertise in multiple related disciplines including speech and hearing science, audiology, engineering, and physiology. The lines of research in the laboratory deal mostly with speech perception by hearing impaired listeners, and particularly those who use cochlear implants (CIs) or hearing aids (HAs). Although the laboratory's research interests are diverse, there are common threads that permeate and tie all of its work. In particular, a strong interest in translational research underlies even the most basic studies carried out in the laboratory. Another important element is the development of engineering and computational tools, which range from mathematical models of speech perception to software and hardware that bypass clinical speech processors and stimulate cochlear implants directly, to novel ways of analyzing clinical outcomes data. If the appropriate tool to conduct an important experiment does not exist, we may work to develop it, either in house or in collaboration with academic or industrial partners. Another notable characteristic of the laboratory is its interdisciplinary nature where, for example, an audiologistandan engineer might work closely to develop an approach that would not have been feasible if each had worked singly on the project. Similarly, investigators with expertise in hearing aids and cochlear implants might join forces to study how human listeners integrate information provided by a CI and a HA. The following pages provide a flavor of the diversity and the commonalities of our research interests. PMID:22668763

  20. Suggestions of Contents and Methods in the Research of Villagers Cooperation%村民合作问题研究的内容和方法建议

    Institute of Scientific and Technical Information of China (English)

    周怀峰

    2013-01-01

    孤立地使用某一学科的内容和方法去研究社会经济问题,往往只能得到对社会经济现象的片面理解。村民合作涉及多方面的因素,需要采用多学科、多元的理论与研究方法。文章以村庄共享资源合作治理为例,对村民合作的研究内容和方法提出若干建议。%If we use only one subject contents and its methods to study the social and economic problems, we often gets one-sided understanding of the social and economic phenomenon. The villagers cooperation involves many factors, the research needs to adopt multiple disciplines,multiple theories and research methods. In addition to the traditional theories and methods, the research should be guided by the contents and methods of behavior and experimental economics, biology, sociology, social psychology, experimental psychology and other theories and methods.This article take the cooperation governance of villages shared resource for example, put forward some suggestions of contents and methods in the fields of villagers cooperation research.

  1. Current Methods in Health Behavior Research Among U.S. Community College Students: A Review of the Literature.

    Science.gov (United States)

    Pokhrel, Pallav; Little, Melissa A; Herzog, Thaddeus A

    2014-06-01

    The majority of health behavior research involving college students in the United States has focused on 4-year college students. Two-year or community college students have been less studied, although a significant proportion of U.S. undergraduates, primarily those from disadvantaged socioeconomic and/or racial/ethnic background, are enrolled in community colleges. Thus, there is a need to enhance health behavior and health promotion research among community college students. This study systematically reviewed 42 published, peer-reviewed health behavior studies conducted among U.S. community college students in order to determine the current state of research in the area with regard to behaviors studied, research designs used, recruitment and data collection strategies practiced, rates of student participation, and characteristics of the participants represented. Findings identified the methodological limitations of current research and suggested optimal recruitment and data collection methods suitable for various research needs. Findings are discussed in the context of enhancing health behavior research among U.S. community college students.

  2. Research on Digital Output Verification Technology of Electronic DC Current Transformer

    Science.gov (United States)

    Chen, Yuanjie; Wang, Bin; Hu, Haoliang; Xiong, Qianzhu; Yang, Chunyan

    2017-05-01

    Aiming at the error of calibration system when conducting field calibration by electronic DC current transformer’s digital calibration system, an electronic DC current transformer’s digital calibration system based on protocol conversion is proposed and researched. Data frames outputted from merging unit are collected and converted by the system, the digital synchronization is realized by using the synchronous clock device to trigger the second pulse, and it is verified by the virtual instrument design software. The field calibration is conducted to some converter station digital dc current transformer under the rated current of 500A by using the calibration system. By calibrating and analyzing errors, the error is less than 0.075% when tested current is more than 40% of the rated current. According the standard in literature[1], performance of the calibration system is perfect, measured results perfectly meet the requirements of design, and the calibration system has great practical application value.

  3. Fracture detection and mapping for geothermal reservoir definition: an assessment of current technology, research, and research needs

    Energy Technology Data Exchange (ETDEWEB)

    Goldstein, N.E.

    1984-11-01

    The detection and mapping of fractures and other zones of high permeability, whether natural or manmade, has been a subject of considerable economic and scientific interest to the pertroleum industry and to the geothermal community. Research related to fractured geothermal reservoirs has been conducted under several past DOE geothermal energy development programs. In this paper we review the present state of technology in fracture detection and mapping. We outline the major problems and limitations of the ''conventional'' techniques, and current research in new technologies. We also present research needs.

  4. An Official American Thoracic Society Research Statement : Current Challenges Facing Research and Therapeutic Advances in Airway Remodeling

    NARCIS (Netherlands)

    Prakash, Y S; Halayko, Andrew J; Gosens, Reinoud; Panettieri Jr., Reynold A; Camoretti-Mercado, Blanca; Penn, Raymond B; Burgess, Janette K

    2017-01-01

    BACKGROUND: Airway remodeling (AR) is a prominent feature of asthma and other obstructive lung diseases that is minimally affected by current treatments. The goals of this Official American Thoracic Society (ATS) Research Statement are to discuss the scientific, technological, economic, and

  5. An Official American Thoracic Society Research Statement : Current Challenges Facing Research and Therapeutic Advances in Airway Remodeling

    NARCIS (Netherlands)

    Prakash, Y S; Halayko, Andrew J; Gosens, Reinoud; Panettieri Jr., Reynold A; Camoretti-Mercado, Blanca; Penn, Raymond B; Burgess, Janette K

    2017-01-01

    BACKGROUND: Airway remodeling (AR) is a prominent feature of asthma and other obstructive lung diseases that is minimally affected by current treatments. The goals of this Official American Thoracic Society (ATS) Research Statement are to discuss the scientific, technological, economic, and regulato

  6. Data standards for clinical research data collection forms: current status and challenges.

    Science.gov (United States)

    Richesson, Rachel L; Nadkarni, Prakash

    2011-05-01

    Case report forms (CRFs) are used for structured-data collection in clinical research studies. Existing CRF-related standards encompass structural features of forms and data items, content standards, and specifications for using terminologies. This paper reviews existing standards and discusses their current limitations. Because clinical research is highly protocol-specific, forms-development processes are more easily standardized than is CRF content. Tools that support retrieval and reuse of existing items will enable standards adoption in clinical research applications. Such tools will depend upon formal relationships between items and terminological standards. Future standards adoption will depend upon standardized approaches for bridging generic structural standards and domain-specific content standards. Clinical research informatics can help define tools requirements in terms of workflow support for research activities, reconcile the perspectives of varied clinical research stakeholders, and coordinate standards efforts toward interoperability across healthcare and research data collection.

  7. Current Status of Doping in Japan Based on Japan Anti-Doping Disciplinary Panels of the Japan Anti-Doping Agency (JADA): A Suggestion on Anti-Doping Activities by Pharmacists in Japan.

    Science.gov (United States)

    Imanishi, Takashi; Kawabata, Takayoshi; Takayama, Akira

    2017-01-01

     In 2009, the Japan Anti-Doping Agency (JADA) established the "Sports Pharmacist Accreditation Program" to prevent doping in sports. Since then, anti-doping activities in Japan have been attracting attention. In this study, we investigated research about the current status of doping from 2007 to 2014 in Japan to make anti-doping activities more concrete, and we also discussed future anti-doping activities by pharmacists. In Japan, bodybuilding was the sporting event with the highest number and rate of doping from 2007 to 2014. Many of the positive doping cases were detected for class S1 (anabolic agents), S5 (diuretics and masking agents), and S6 (stimulants). Within class S1, supplements were the main cause of positive doping. Within class S5, medicines prescribed by medical doctors were the main cause of positive doping. Within class S6, non-prescription medicines (e.g., OTC) were the main cause of positive doping. When we looked at the global statistics on doping, many of the positive doping cases were detected for class S1. On comparing the Japanese statistics with the global statistics, the rate of positive doping caused by class S1 was significantly lower, but that caused by classes S5 and S6 was significantly higher in Japan than in the world. In conclusion, pharmacists in Japan should pay attention to class S1, S5, and S6 prohibited substances and to the sport events of bodybuilding. Based on this study, sports pharmacists as well as common pharmacists should suggest new anti-doping activities to prevent doping in the future.

  8. Greenhouse gas emissions from natural ecosystems and agricultural lands in sub-Saharan Africa: synthesis of available data and suggestions for further research

    Science.gov (United States)

    Kim, Dong-Gill; Thomas, Andrew D.; Pelster, David; Rosenstock, Todd S.; Sanz-Cobena, Alberto

    2016-08-01

    This paper summarizes currently available data on greenhouse gas (GHG) emissions from African natural ecosystems and agricultural lands. The available data are used to synthesize current understanding of the drivers of change in GHG emissions, outline the knowledge gaps, and suggest future directions and strategies for GHG emission research. GHG emission data were collected from 75 studies conducted in 22 countries (n = 244) in sub-Saharan Africa (SSA). Carbon dioxide (CO2) emissions were by far the largest contributor to GHG emissions and global warming potential (GWP) in SSA natural terrestrial systems. CO2 emissions ranged from 3.3 to 57.0 Mg CO2 ha-1 yr-1, methane (CH4) emissions ranged from -4.8 to 3.5 kg ha-1 yr-1 (-0.16 to 0.12 Mg CO2 equivalent (eq.) ha-1 yr-1), and nitrous oxide (N2O) emissions ranged from -0.1 to 13.7 kg ha-1 yr-1 (-0.03 to 4.1 Mg CO2 eq. ha-1 yr-1). Soil physical and chemical properties, rewetting, vegetation type, forest management, and land-use changes were all found to be important factors affecting soil GHG emissions from natural terrestrial systems. In aquatic systems, CO2 was the largest contributor to total GHG emissions, ranging from 5.7 to 232.0 Mg CO2 ha-1 yr-1, followed by -26.3 to 2741.9 kg CH4 ha-1 yr-1 (-0.89 to 93.2 Mg CO2 eq. ha-1 yr-1) and 0.2 to 3.5 kg N2O ha-1 yr-1 (0.06 to 1.0 Mg CO2 eq. ha-1 yr-1). Rates of all GHG emissions from aquatic systems were affected by type, location, hydrological characteristics, and water quality. In croplands, soil GHG emissions were also dominated by CO2, ranging from 1.7 to 141.2 Mg CO2 ha-1 yr-1, with -1.3 to 66.7 kg CH4 ha-1 yr-1 (-0.04 to 2.3 Mg CO2 eq. ha-1 yr-1) and 0.05 to 112.0 kg N2O ha-1 yr-1 (0.015 to 33.4 Mg CO2 eq. ha-1 yr-1). N2O emission factors (EFs) ranged from 0.01 to 4.1 %. Incorporation of crop residues or manure with inorganic fertilizers invariably resulted in significant changes in GHG emissions, but results were inconsistent as the magnitude and direction of

  9. Suggestions on Perfecting the Scientific Research Item Guide Establishment%完善科研项目指南编制的建议

    Institute of Scientific and Technical Information of China (English)

    朱杰堂

    2011-01-01

    目前科研项目指南编制中出现的主要问题有:对调研论证的时间要求太紧;论证环节只召集少数部门领导和朋友座谈一下草草了事;设置部分定向委托课题时人为使某些项目失去公平的申请机会;指南发布距提交申请材料的时间较太短;等等。应高度重视项目指南编制的重要性和规范性,广泛征集建议选题,提高专家论证选题的质量,取消定向委托课题,优化指南发布,以提升项目指南的编制质量和实现项目申请的公平、公正和公开。%The main problems existing in the present scientific research item guide establishment include the followings. Firstly, time for the research and investigation is very limited; Secondly, only few department leaders and the friends are called to discuss the guide in the process of comprehensive analysis of the project guide; Thirdly, fair application opportunities of certain scientific research item lose artificially and so on. It is suggested that more attention should be paid to the importance and standards, suggestions of the selected topics widely collected, the selected topic quality of the expert enhanced, the directional request topics canceled, the guide issue optimized, so that the quality of the project guide establishment can be promoted and the fairness and openness realized.

  10. Informed consent in human subject research: a comparison of current international and Nigerian guidelines.

    Science.gov (United States)

    Fadare, Joseph O; Porteri, Corinna

    2010-03-01

    Informed consent is a basic requirement for the conduct of ethical research involving human subjects. Currently, the Helsinki Declaration of the World Medical Association and the International Ethical Guidelines for Biomedical Research of the Council for International Organizations of Medical Sciences (CIOMS) are widely accepted as international codes regulating human subject research and the informed consent sections of these documents are quite important. Debates on the applicability of these guidelines in different socio-cultural settings are ongoing and many workers have advocated the need for national or regional guidelines. Nigeria, a developing country, has recently adopted its national guideline regulating human subject research: the National Health Research Ethics Committee (NHREC) code. A content analysis of the three guidelines was done to see if the Nigerian guidelines confer any additional protection for research subjects. The concept of a Community Advisory Committee in the Nigerian guideline is a novel one that emphasizes research as a community burden and should promote a form of "research friendship" to foster the welfare of research participants. There is also the need for a regular update of the NHREC code so as to address some issues that were not considered in its current version.

  11. Research on Measurement of Bed Shear Stress Under WaveCurrent Interaction

    Institute of Scientific and Technical Information of China (English)

    徐华; 夏云峰; 张世钊马炳和; 郝思禹; 杜德军

    2015-01-01

    The movement of sediment in estuary and on coast is directly restricted by the bed shear stress. Therefore, the research on the basic problem of sediment movement by the bed shear stress is an important way to research the theory of sediment movement. However, there is not a measuring and computing method to measure the bed shear stress under a complicated dynamic effect like wave and current. This paper describes the measurement and test research on the bed shear stress in a long launder of direct current by the new instrument named thermal shearometer based on micro-nanotechnology. As shown by the research results, the thermal shearometer has a high response frequency and strong stability. The measured results can reflect the basic change of the bed shear stress under wave and wave-current effect, and confirm that the method of measuring bed shear stress under wave-current effect with thermal shearometer is feasible. Meanwhile, a preliminary method to compute the shear stress compounded by wave-current is put forward according to the tested and measured results, and then a reference for further study on the basic theory of sediment movement under a complicated dynamic effect is provided.

  12. Mindfulness-Based Stress Reduction and Transcendental Meditation: Current State of Research

    Directory of Open Access Journals (Sweden)

    Adam Holt

    2015-04-01

    Full Text Available This article summarizes the current state of meditation research, specifically focusing on mindfulness-based stress reduction and transcendental meditation. Despite significant methodological problems with the studies reported to date on the subject, there is consistent evidence that meditation can produce changes in the nervous system and physiology of the meditator, and can help with various psychological markers of well-being. Regarding improvement in specific clinical diseases, research is generally mixed and preliminary. Strong recommendations cannot be made based on current evidence, and further studies are needed. In general, there is a stronger body of evidence supporting mindfulness-based stress reduction than for transcendental meditation.

  13. Research on the induction motor current signature for centrifugal pump at cavitation condition

    Directory of Open Access Journals (Sweden)

    Yin Luo

    2015-11-01

    Full Text Available Cavitation is a major undesirable phenomenon for centrifugal pump because it can cause hydraulic performance deterioration, pump damage by pitting and material erosion, and structural vibration and noise. Cavitation can appear within the entire range of the operating conditions; therefore, it must be prevented by all means. Sensorless monitoring technology based on motor current signature analysis is non-intrusive and economic for monitoring motor-driven equipment. Thus, this technology is suitable for centrifugal pump systems. The motor current signature for centrifugal pump load at the cavitation condition is the basis of this technology. However, systematic research is lacking on sensorless monitoring technology based on motor current signature. As a result, the tentative exploration for motor current signature at cavitation load was conducted in this study. The results show that the stator current is still a sinusoidal alternating current strictly to the law of sine. Moreover, the root mean square of the current fluctuates because of different flow regimes in the cavitation progress and decreases because vapor density is smaller than water density when cavitation is fully formed. For the stator current spectrum, the noise level, noise distribution, rotation speed, and vane pass frequency components show features in the cavitation process. These indicator indexes change according to the stage of cavitation development. Thus, the motor current signature analysis is found to be a feasible and cost-effective method for the stages of cavitation condition.

  14. Retrospectives, current valences and prospective dimensions of research at the Academy of Public Administration

    Directory of Open Access Journals (Sweden)

    Aurel SÎMBOTEANU

    2016-12-01

    Full Text Available The present study is an attempt to identify the social determinants, which initiated and facilitated the content and evolution of the scientific research of the administrative phenomenon in the Republic of Moldova after the declaration of independence. It also elucidates the current valences and perspectives of this activity in the context of the provisions of the recently adopted Research Strategy of the Academy of Public Administration for the period 2016-2020.

  15. Suggestions for Teaching Practice

    Institute of Scientific and Technical Information of China (English)

    ZHAN Na-na

    2013-01-01

    Teacher development and teaching practice(TP) have caught the eyes of researchers at home and abroad for many years. Many western scholars hold that reflective teaching is an efficient way to promote teacher development, but traditional TP is prevailing in China. Based on the merits and demerits of traditional TP and reflective TP, the author hopes to provide some suggestions for the people involved to promote the development of teacher education.

  16. Neonatal research in India: current status, challenges, and the way forward.

    Science.gov (United States)

    Gupta, Shuchita; Chaurasia, Suman; Sankar, M Jeeva; Deorari, Ashok K; Paul, Vinod K; Agarwal, Ramesh

    2014-11-01

    The present article systematically reviews the current status of neonatal research in India by examining the research articles published by Indian authors in the last 10 years. It also enlists the major challenges and proposes a few potential solutions to improve the status of neonatal research in the country. The systematic review of 574 eligible articles indicates that majority of the studies were observational in nature, facility-based, and primarily investigator-driven with no external funding, had small sample size, and were published in journals with low impact factor. Only a few select government and non-government academic institutions contributed to most studies. The major challenges include shortage of faculty, no provision for dedicated research time, inadequate knowledge/skills in research methods, lack of funding opportunities, limited access to literature, non-existence of research administrative cell, inappropriately low perks to research staff, and poor support for data management and statistical analysis. The recently revised guidelines on clinical trials involving drugs have further increased the researcher's dilemma. The potential solutions are to increase the faculty strength in medical colleges, allow dedicated research time to them, appoint dedicated research cadre with emoluments at par with clinical faculty, initiate formal training in research methods, create nationwide free portal for access to literature, facilitate development of good protocols through technical guidance at all stages, make the process of funding quick and transparent, and to promote collaborative trans-disciplinary research. Experts from different domains should come together and formulate evidence based research priorities. Regulatory mechanisms should be kept proportionate to plausible risks of research, and detailed ethical guidelines for research in children should be formulated. And last but not least, harnessing postgraduate thesis potential to answer simple and

  17. Evolutionary multi-objective optimization: some current research trends and topics that remain to be explored

    Institute of Scientific and Technical Information of China (English)

    Carlos A. COELLO COELLO

    2009-01-01

    This paper provides a short review of some of the main topics in which the current research in evolutionary multi-objective optimization is being focused. The topics discussed include new algorithms, efficiency, relaxed forms of dominance, scalability, and alternative metaheuristics. This discussion motivates some further topics which,from the author's perspective, constitute good potential areas for future research, namely, constraint-handling techniques,incorporation of user's preferences and parameter control,This information is expected to be useful for those interested in pursuing research in this area.

  18. A few perspectives of solar physics research in China - current status and future

    Science.gov (United States)

    Wang, Jingxiu; Ding, Mingde; Ji, Haisheng; Deng, Yuanyong; Liu, Yu; Liu, Zhong; Qu, Zhongquan; Wang, Huaning; Xia, Lidong; Yan, Yihua

    2016-07-01

    Solar physics research as an important discipline in astrophysics in China aims at improving the understanding of origin and variation of solar magnetic field and magnetic activity, and founding the basis for forecast of disastrous space weather. The current review is focused on the solar physics research in China in recent three years. Highlights in scientific research in solar magnetism, magnetic activity, coronal plasma, and space weather forecast are briefly summarized. Key advances in instrument development are reported in some necessary details. Future tendency and working direction are considered and discussed.

  19. Review of Current Status and Research Approaches to Nitrogen Pollution in Farmlands

    Institute of Scientific and Technical Information of China (English)

    NIE Sheng-wei; GAO Wang-sheng; CHEN Yuan-quan; SUI Peng; A Egrinya Eneji

    2009-01-01

    In this paper, the history, current status, and research approaches to nitrogen pollution were reviewed using systems analysis and deductions. The seriousness of N pollution world-wide was highlighted and recommendations were made to address the situation. A new hypothesis based on phytoremediation, which means the use of plants to directly or indirectly degrade or remove contaminats from soil and water, was proposed.

  20. Gravitational radiation theory. M.A. Thesis - Rice Univ.; [survey of current research

    Science.gov (United States)

    Wilson, T. L.

    1973-01-01

    A survey is presented of current research in the theory of gravitational radiation. The mathematical structure of gravitational radiation is stressed. Furthermore, the radiation problem is treated independently from other problems in gravitation. The development proceeds candidly through three points of view - scalar, rector, and tensor radiation theory - and the corresponding results are stated.

  1. Current status of neutron activation analysis using the Dalat Nuclear Research Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Nguyen Van Suc; Nguyen Mong Sinh [Nuclear Research Institute, Dalat (Viet Nam)

    1999-10-01

    Neutron activation analysis is one of the most sensitive, rapid, accurated methods for determination of trace elements in different materials. A review is made of the current status of the activities and the results in studying and developing NAA (Neutron Activation Analysis) at the Dalat Nuclear Research Institute and applying this method to different sectors of science and technology in Vietnam. (author)

  2. Current status and progress of research on the management of bean ...

    African Journals Online (AJOL)

    ©2000 National Agricultural Research Organisation. Current status ... Them a in ohj ective of this study was to identify control measures that can reduce the disease on ... practices in controlling root rot was carried out in 1997 for two seasons ...

  3. First Language Transfer in Second Language Writing: An Examination of Current Research

    Science.gov (United States)

    Karim, Khaled; Nassaji, Hossein

    2013-01-01

    First language (L1) transfer has been a key issue in the field of applied linguistics, second language acquisition (SLA), and language pedagogy for almost a century. Its importance, however, has been re-evaluated several times within the last few decades. The aim of this paper is to examine current research that has investigated the role of L1…

  4. Fusarium mycotoxins: Current research at the USDA ARS Mycotoxin Prevention unit

    Science.gov (United States)

    Due to the health and economic costs of mycotoxins produced by Fusarium species, there is a compelling need for improved understanding of these fungi, from across diverse perspectives and disciplinary approaches. Current research at the USDA ARS Mycotoxin Prevention unit addresses Fusarium mycotoxin...

  5. Delivering patient decision aids on the Internet: definitions, theories, current evidence, and emerging research areas

    Science.gov (United States)

    2013-01-01

    Background In 2005, the International Patient Decision Aids Standards Collaboration identified twelve quality dimensions to guide assessment of patient decision aids. One dimension—the delivery of patient decision aids on the Internet—is relevant when the Internet is used to provide some or all components of a patient decision aid. Building on the original background chapter, this paper provides an updated definition for this dimension, outlines a theoretical rationale, describes current evidence, and discusses emerging research areas. Methods An international, multidisciplinary panel of authors examined the relevant theoretical literature and empirical evidence through 2012. Results The updated definition distinguishes Internet-delivery of patient decision aids from online health information and clinical practice guidelines. Theories in cognitive psychology, decision psychology, communication, and education support the value of Internet features for providing interactive information and deliberative support. Dissemination and implementation theories support Internet-delivery for providing the right information (rapidly updated), to the right person (tailored), at the right time (the appropriate point in the decision making process). Additional efforts are needed to integrate the theoretical rationale and empirical evidence from health technology perspectives, such as consumer health informatics, user experience design, and human-computer interaction. Despite Internet usage ranging from 74% to 85% in developed countries and 80% of users searching for health information, it is unknown how many individuals specifically seek patient decision aids on the Internet. Among the 86 randomized controlled trials in the 2011 Cochrane Collaboration’s review of patient decision aids, only four studies focused on Internet-delivery. Given the limited number of published studies, this paper particularly focused on identifying gaps in the empirical evidence base and

  6. Current Understandings of the Research-Practice Gap From the Viewpoint of Complementary Medicine Academics: A Mixed-Method Investigation.

    Science.gov (United States)

    Leach, Matthew J; Tucker, Basil

    Research plays an important role in advancing health and healthcare. However, much research evidence is not reflected in contemporary complementary and alternative medicine (CAM) practice. Understanding and addressing the reasons for this research-practice gap may have positive implications for quality of care. To shed light on the gap between research and CAM practice. Descriptive cross-sectional, mixed-method study. A total of 126 senior CAM academics across Australasia, Europe, UK, and North America. Participants completed a 30-item online survey and a semi-structured interview; both of which explored the research-practice gap in CAM. A total of 43 (34%) academics completed the survey, with 29 (67%) respondents undergoing an interview. There was general agreement among respondents that CAM research should be informed by practice, and practice informed by research; however, most agreed that this did not reflect the current situation. Translational issues were perceived to be the primary reason for the research-practice gap in CAM. Suggested strategies for closing the gap focussed mostly around improving CAM student/practitioner education and training, and researcher-practitioner engagement and collaboration. Study findings point toward the presence of a research-practice gap in CAM, with several factors likely to be instrumental in sustaining this gap. Attention now needs to focus on understanding the views of CAM clinicians on this issue. Insights gained from this research will help inform the development of a multi-modal strategy that will effectively target the barriers to change in order to bring CAM research and practice closer together. Copyright © 2017 Elsevier Inc. All rights reserved.

  7. The emergence and current performance of a health research system: lessons from Guinea Bissau

    Directory of Open Access Journals (Sweden)

    Kok Maarten O

    2012-02-01

    Full Text Available Abstract Background Little is known about how health research systems (HRS in low-income countries emerge and evolve over time, and how this process relates to their performance. Understanding how HRSs emerge is important for the development of well functioning National Health Research Systems (NHRS. The aim of this study was to assess how the HRS in Guinea Bissau has emerged and evolved over time and how the present system functions. Methods We used a qualitative case-study methodology to explore the emergence and current performance of the HRS, using the NHRS framework. We reviewed documents and carried out 39 in-depth interviews, ranging from health research to policy and practice stakeholders. Using an iterative approach, we undertook a thematic analysis of the data. Results The research practices in Guinea Bissau led to the emergence of a HRS with both local and international links and strong dependencies on international partners and donors. The post-colonial, volatile and resource-dependent context, changes in donor policies, training of local researchers and nature of the research findings influenced how the HRS evolved. Research priorities have mostly been set by 'expatriate' researchers and focused on understanding and reducing child mortality. Research funding is almost exclusively provided by foreign donors and international agencies. The training of Guinean researchers started in the mid-nineties and has since reinforced the links with the health system, broadened the research agenda and enhanced local use of research. While some studies have made an important contribution to global health, the use of research within Guinea Bissau has been constrained by the weak and donor dependent health system, volatile government, top-down policies of international agencies, and the controversial nature of some of the research findings. Conclusions In Guinea Bissau a de facto 'system' of research has emerged through research practices and co

  8. Statistical research on the motion properties of the magnetotail current sheet:Cluster observations

    Institute of Scientific and Technical Information of China (English)

    H.REME; E.LUCEK

    2010-01-01

    The origin of the flapping motion of the earth’s magnetotail current sheet is one of the most important problems in the magnetotail dynamics.Using Cluster data,we make a statistical research on the motion properties of the magnetotail current sheet of 2001 and 2003.We calculate the velocities of the magnetotail current sheet using new methods and obtain the distribution of the magnetotail current sheet velocities in the X-Y plane in GSE coordinate system.Our results show that although most of the current sheets were propagating toward the tail flanks and those of the exceptions lay in dusk side,which is consistent with previous studies,the proportions of the current sheet which were propagating toward midnight (where |YGSE|=0) were higher than those in previous studies.Motions of the current sheet in the middle area (|YGSE|<8 Re) of the magnetotail are investigated.Relatively high value of the Z component of the velocity further confirms that the middle area of the magnetotail might be a source region for the motion of the current sheets which were propagating towards the tail flanks.According to our case studies,the way the current sheets propagated toward midnight area differs significantly from that toward dusk and dawn side,from which we infer that there might be two different kinds of current sheet motions originated from different sources.The statistical results of this paper may give some clues for further studies on the origin of the flapping motion of the magnetotail current sheet.

  9. Current Researches on the Methods of Diagnosing Sasang Constitution: An Overview

    Directory of Open Access Journals (Sweden)

    Si-Woo Lee

    2009-01-01

    Full Text Available Sasang constitution diagnosis has traditionally been conducted by a Sasang constitutional medicine (SCM doctor who examines the external appearance, temperament and various symptoms of an individual and then collectively analyzes this information to determine their own constitutions. However, because this process is subjective and not quantitative, many researchers have been attempting to develop objective and reasonable methods of determining constitutions. In Korea, even though a wide range of research regarding SCM has been conducted, most of the work has not been revealed internationally. So in this review, the authors have searched the Journal of Sasang Constitutional Medicine, as well as other Korean domestic journal databases and Pubmed for research regarding modernized constitution diagnosis methods so to provide the understanding of current research state and outlook for future research.

  10. African swine fever virus: current state and future perspectives in vaccine and antiviral research.

    Science.gov (United States)

    Zakaryan, Hovakim; Revilla, Yolanda

    2016-03-15

    African swine fever (ASF) is among the most significant of swine diseases for which no effective vaccines and antivirals are available. The disease, which is endemic in Africa, was introduced to Trans-Caucasian countries and the Russian Federation in 2007, where it remains prevalent today among domestic pigs and wild boars. Although some measures were implemented, ASF continues to pose a global risk for all countries, and thereby highlighting the importance of vaccine and antiviral research. In this review, an overview of research efforts toward the development of effective vaccines during the past decades is presented. As an alternative to vaccine development, the current state in antiviral research against ASFV is also presented. Finally, future perspectives in vaccine and antiviral research giving emphasis on some strategies that may allow researchers to develop effective countermeasures against ASF are discussed.

  11. Return of the "intimate outsider": current trends and issues in family nursing research revisited.

    Science.gov (United States)

    Ganong, Lawrence

    2011-11-01

    This article reviews family nursing research published from 1996 to 2011. This is a follow-up to a review published in the Journal of Family Nursing in 1995. Findings from the first review are compared with this one, trends in family nursing scholarship are identified, and predictions and suggestions for future directions are offered. The latest generation of family nursing scholarship is conceptually and methodologically sound, and there is evidence of more multidisciplinary and interdisciplinary research conducted by family nursing researchers. Scholars are paying more attention to issues of diversity and family context at present than in the past, although there are still aspects of diversity that need more attention. Strong research programs in family nursing exist worldwide; an international synergism has helped promote rapid expansion of family nursing research and theory development. A vigorous movement to promote research to practice initiatives and greater attention to family interventions are exciting developments.

  12. [Pathological gambling and computergame-addiction. Current state of research regarding two subtypes of behavioural addiction].

    Science.gov (United States)

    Wölfling, K; Müller, K W

    2010-04-01

    Behavioral addictions, like pathological gambling and computer game addiction (or internet addiction), have become a growing concern in research and public interest. Currently similarities between behavioral addictions and substance dependency are controversially discussed in the scientific community. Unfortunately a mismatch exists between the large number of people seeking treatment and the small number of scientific studies on pathological gambling and computer game addiction. Prevalence of pathological gambling among the German population is estimated to be 0.2-0.5%. These estimations are comparable to prevalence rates reported for drug dependency. Latest research states that about 3% of German adolescents and young adults are believed to suffer from computer game addiction. Therefore, it is important to enhance investigations regarding the clinical and neuroscientific basis of computer game addiction. This review offers a summary of current results of research regarding pathological gambling and internet addiction. The phenomenological description of these two disorders is meant to allow a deeper understanding of behavioral addictions.

  13. Experimental Research of Harmonic Spectrum of Currents at Traction Drive with PMSM

    Directory of Open Access Journals (Sweden)

    J. Novak

    2011-06-01

    Full Text Available The paper deals with the significant results of the experimental research of current harmonic spectrum of traction drive with permanent magnet synchronous motor. The experiments were done on a special workplace with a real traction drive for wheel vehicles. Current harmonic spectrum was analyzed by a specialized device on the base of central measuring station. The knowledge of current marked subharmonic components of stator winding is the most significant finding of experiments. The frequencies of these components are given by multiples of frequency of mechanical speeds. The subharmonic components also pass to input DC current of drive. This fact is important in particular from the point of view of legislative requirements to electromagnetic compatibility of drive with railway interlocking devices.

  14. Research on resistance characteristics of YBCO tape under short-time DC large current impact

    Science.gov (United States)

    Zhang, Zhifeng; Yang, Jiabin; Qiu, Qingquan; Zhang, Guomin; Lin, Liangzhen

    2017-06-01

    Research of the resistance characteristics of YBCO tape under short-time DC large current impact is the foundation of the developing DC superconducting fault current limiter (SFCL) for voltage source converter-based high voltage direct current system (VSC-HVDC), which is one of the valid approaches to solve the problems of renewable energy integration. SFCL can limit DC short-circuit and enhance the interrupting capabilities of DC circuit breakers. In this paper, under short-time DC large current impacts, the resistance features of naked tape of YBCO tape are studied to find the resistance - temperature change rule and the maximum impact current. The influence of insulation for the resistance - temperature characteristics of YBCO tape is studied by comparison tests with naked tape and insulating tape in 77 K. The influence of operating temperature on the tape is also studied under subcooled liquid nitrogen condition. For the current impact security of YBCO tape, the critical current degradation and top temperature are analyzed and worked as judgment standards. The testing results is helpful for in developing SFCL in VSC-HVDC.

  15. Current Knowledge and Future Research on Infant Feeding in the Context of HIV: Basic, Clinical, Behavioral, and Programmatic Perspectives12

    Science.gov (United States)

    Young, Sera L.; Mbuya, Mduduzi N. N.; Chantry, Caroline J.; Geubbels, Eveline P.; Israel-Ballard, Kiersten; Cohan, Deborah; Vosti, Stephen A.; Latham, Michael C.

    2011-01-01

    In 2008, between 129,000 and 194,000 of the 430,000 pediatric HIV infections worldwide were attributable to breastfeeding. Yet in many settings, the health, economic, and social consequences of not breastfeeding would have dire consequences for many more children. In the first part of this review we provide an overview of current knowledge about infant feeding in the context of HIV. Namely, we describe the benefits and risks of breastmilk, the evolution of recommended infant feeding modalities in high-income and low-income countries in the last two decades, and contextualize the recently revised guidelines for infant feeding in the context of HIV current knowledge. In the second section, we suggest areas for future research on the postnatal prevention of mother-to-child transmission of HIV (PMTCT) in developing and industrialized countries. We suggest two shifts in perspective. The first is to evaluate PMTCT interventions more holistically, to include the psychosocial and economic consequences as well as the biomedical ones. The second shift in perspective should be one that contextualizes postnatal PMTCT efforts in the cascade of maternal health services. We conclude by discussing basic, clinical, behavioral, and programmatic research questions pertaining to a number of PMTCT efforts, including extended postnatal ARV prophylaxis, exclusive breastfeeding promotion, counseling, breast milk pasteurization, breast milk banking, novel techniques for making breast milk safer, and optimal breastfeeding practices. We believe the research efforts outlined here will maximize the number of healthy, thriving, HIV-free children around the world. PMID:22332055

  16. Fuel-coolant interaction (FCI) phenomena in reactor safety. Current understanding and future research needs

    Energy Technology Data Exchange (ETDEWEB)

    Speis, T.P. [Maryland Univ., College Park, MD (United States); Basu, S.

    1998-01-01

    This paper gives an account of the current understanding of fuel-coolant interaction (FCI) phenomena in the context of reactor safety. With increased emphasis on accident management and with emerging in-vessel core melt retention strategies for advanced light water reactor (ALWR) designs, recent interest in FCI has broadened to include an evaluation of potential threats to the integrity of reactor vessel lower head and ex-vessel structural support, as well as the role of FCI in debris quenching and coolability. The current understanding of FCI with regard to these issues is discussed, and future research needs to address the issues from a risk perspective are identified. (author)

  17. Improving performance in golf: current research and implications from a clinical perspective

    Directory of Open Access Journals (Sweden)

    Kerrie Evans

    2015-10-01

    Full Text Available ABSTRACTGolf, a global sport enjoyed by people of all ages and abilities, involves relatively long periods of low intensity exercise interspersed with short bursts of high intensity activity. To meet the physical demands of full swing shots and the mental and physical demands of putting and walking the course, it is frequently recommended that golfers undertake golf-specific exercise programs. Biomechanics, motor learning, and motor control research has increased the understanding of the physical requirements of the game, and using this knowledge, exercise programs aimed at improving golf performance have been developed. However, while it is generally accepted that an exercise program can improve a golfer's physical measurements and some golf performance variables, translating the findings from research into clinical practice to optimise an individual golfer's performance remains challenging. This paper discusses how biomechanical and motor control research has informed current practice and discusses how emerging sophisticated tools and research designs may better assist golfers improve their performance.

  18. Current thinking in qualitative research: evidence-based practice, moral philosophies, and political struggle.

    Science.gov (United States)

    Papadimitriou, Christina; Magasi, Susan; Frank, Gelya

    2012-01-01

    In this introduction to the special issue on current thinking in qualitative research and occupational therapy and science, the authors focus on the importance of rigorous qualitative research to inform occupational therapy practice. The authors chosen for this special issue reflect a "second generation of qualitative researchers" who are critical, theoretically sophisticated, methodologically productive, and politically relevant to show that working with disabled clients is political work. Three themes emerged across the articles included in this special issue: (1) recognizing and addressing social justice issues; (2) learning from clients' experiences; and (3) critically reframing occupational therapy's role. These themes can inform occupational therapy practice, research, and education to reflect a more client-centered and politically engaging approach. Copyright 2012, SLACK Incorporated.

  19. Single-Case Experimental Designs: A Systematic Review of Published Research and Current Standards

    Science.gov (United States)

    Smith, Justin D.

    2013-01-01

    This article systematically reviews the research design and methodological characteristics of single-case experimental design (SCED) research published in peer-reviewed journals between 2000 and 2010. SCEDs provide researchers with a flexible and viable alternative to group designs with large sample sizes. However, methodological challenges have precluded widespread implementation and acceptance of the SCED as a viable complementary methodology to the predominant group design. This article includes a description of the research design, measurement, and analysis domains distinctive to the SCED; a discussion of the results within the framework of contemporary standards and guidelines in the field; and a presentation of updated benchmarks for key characteristics (e.g., baseline sampling, method of analysis), and overall, it provides researchers and reviewers with a resource for conducting and evaluating SCED research. The results of the systematic review of 409 studies suggest that recently published SCED research is largely in accordance with contemporary criteria for experimental quality. Analytic method emerged as an area of discord. Comparison of the findings of this review with historical estimates of the use of statistical analysis indicates an upward trend, but visual analysis remains the most common analytic method and also garners the most support amongst those entities providing SCED standards. Although consensus exists along key dimensions of single-case research design and researchers appear to be practicing within these parameters, there remains a need for further evaluation of assessment and sampling techniques and data analytic methods. PMID:22845874

  20. Person-centred health care: a critical assessment of current and emerging research approaches.

    Science.gov (United States)

    Martin, Carmel M; Félix-Bortolotti, Margot

    2014-12-01

    Person-centred health care is prominent in international health care reforms. A shift to understanding and improving personal care at the point of delivery has generated debates about the nature of the person-centred research agenda. This paper purviews research paradigms that influence current person-centred research approaches and traditions that influence knowledge foundations in the field. It presents a synthesis of the emergent approaches and methodologies and highlights gaps between static academic research and the increasing accessibility of evaluation, informatics and big data from health information systems. Paradigms in health services research range from theoretical to atheoretical, including positivist, interpretive, postmodern and pragmatic. Interpretivist (subjective) and positivist (objectivist) paradigms have been historically polarized. Yet, integrative and pragmatic approaches have emerged. Nevertheless, there is a tendency to reductionism, and to reduce personal experiences to metrics in the positivist paradigm. Integrating personalized information into clinical systems is increasingly driven by the pervasive health information technology, which raises many issues about the asymmetry and uncertainty in the flow of information to support personal health journeys. The flux and uncertainty of knowledge between and within paradigmatic or pragmatic approaches highlights the uncertainty and the 'unorder and disorder' in what is known and what it means. Transdisciplinary, complex adaptive systems theory with multi-ontology sense making provides an overarching framework for making sense of the complex dynamics in research progress. A major challenge to current research paradigms is focus on the individualizing of care and enhancing experiences of persons in health settings. There is an urgent need for person-centred research to address this complex process. A transdisciplinary and complex systems approach provides a sense-making framework. © 2014 John

  1. Current state of information technology use in a US primary care practice-based research network

    Directory of Open Access Journals (Sweden)

    James Andrews

    2004-02-01

    Conclusion While interest in enabling information technologies was high in KAN, adoption was variable, with use of several key technologies reported as low.The results suggest that research in this network that would be dependent on or enhanced by IT might be impeded and, generally, greater attention should be given to enhancing the IT infrastructure in primary care.

  2. Current Trends in Educational Technology Research in Turkey in the New Millennium

    Science.gov (United States)

    Simsek, Ali; Ozdamar, Nilgun; Uysal, Omer; Kobak, Kadriye; Berk, Cem; Kilicer, Tugba; Cigdem, Harun

    2009-01-01

    This study examined 259 master's theses in the field of educational technology completed in Turkey during 2000-2007. The results suggested that quantity and quality of educational technology research varied according to years and universities. A great majority of the theses employed quantitative paradigm, and qualitative studies made about one…

  3. The Declaration of Helsinki in relation to medical research: historical and current perspectives.

    Science.gov (United States)

    Shrestha, B M

    2012-09-01

    Medical research aims at improving diagnostic, therapeutic and prophylactic measures and understanding of the aetiology and pathogenesis of diseases in humans, and their application to improve the quality of life and survival. The subjects involved are exposed to hazards inherent to the experiments. In order to protect the human subjects and to maintain high ethical standards, the World Medical Association had adopted the "Declaration of Helsinki" in 1964. The aim of this article is to provide a comprehensive review on the historical and current perspectives on the Declaration of Helsinki in relation to medical research on human subjects.

  4. [Current situation of toxicity classification of Chinese materia medica and its research thoughts].

    Science.gov (United States)

    Sun, Wenyan; Hou, Xiujuan; Wang, Bin; Zhu, Yuelan; Zhang, Shuofeng; Chang, Hongsheng; Sun, Jianning

    2012-08-01

    Toxicity of Chinese materia medica (CMM) is an important part of Chinese herbal nature theory. In clinical application, the dosage, time limitation and compatibility of CMM is mainly determined by toxicity. At present, there is no uniform toxicity classification standard for the evaluation of Chinese herbal toxicity. Therefore, it is significant to research toxicity classification of CMM. The current situation of toxicity classification of CMM is reviewed in this paper, and proposed research thoughts are as follows: the measurement of toxicity parameters, the confirmation of poisoning target organs, the investigation on toxic mechanism by serum pharmacology and toxicokinetics, the comprehensive evaluation on toxicity based on quantitative theory.

  5. The current state of the art of quantitative phosphoproteomics and its applications to diabetes research

    Energy Technology Data Exchange (ETDEWEB)

    Chan, Chi Yuet X’avia; Gritsenko, Marina A.; Smith, Richard D.; Qian, Wei-Jun

    2016-03-17

    Protein phosphorylation is a fundamental regulatory mechanism in many cellular processes and aberrant perturbation of phosphorylation has been revealed in various human diseases. Kinases and their cognate inhibitors have been hotspot for drug development. Therefore, the emerging tools, which enable a system-wide quantitative profiling of phosphoproteome, would offer a powerful impetus in unveiling novel signaling pathways, drug targets and/or biomarkers for the disease of interest. In this review, we will highlight recent advances in phosphoproteomics, the current state-of-the-art of the technologies, and the challenges and future perspectives of this research area. Finally, we will underscore some exemplary applications of phosphoproteomics in diabetes research.

  6. The current state of the art of quantitative phosphoproteomics and its applications to diabetes research.

    Science.gov (United States)

    Chan, Chi Yuet X'avia; Gritsenko, Marina A; Smith, Richard D; Qian, Wei-Jun

    2016-01-01

    Protein phosphorylation is a fundamental regulatory mechanism in many cellular processes and aberrant perturbation of phosphorylation has been implicated in various human diseases. Kinases and their cognate inhibitors have been considered as hotspots for drug development. Therefore, the emerging tools, which enable a system-wide quantitative profiling of phosphoproteome, would offer a powerful impetus in unveiling novel signaling pathways, drug targets and/or biomarkers for diseases of interest. This review highlights recent advances in phosphoproteomics, the current state of the art of the technologies and the challenges and future perspectives of this research area. Finally, some exemplary applications of phosphoproteomics in diabetes research are underscored.

  7. Central centrifugal cicatricial alopecia: what has been achieved, current clues for future research.

    Science.gov (United States)

    Ogunleye, Temitayo A; McMichael, Amy; Olsen, Elise A

    2014-04-01

    Central centrifugal cicatricial alopecia is an inflammatory type of central scalp hair loss seen primarily in women of African descent. The prevalence is unknown, but may vary from 2.7% to 5.7% and increases with age. This review outlines the history and current beliefs and identifies clues for future research for this enigmatic condition. Despite that the cause of central centrifugal cicatricial alopecia is unknown, research is ongoing. The role of cytokeratins, androgens, genetics, and various possible sources of chronic inflammation in disease pathogenesis remain to be elucidated.

  8. Energy and materials conservation: applying pioneering research and techniques to current non-energy materials conservation issues.

    Science.gov (United States)

    Hannon, Bruce

    2013-03-13

    The research of the Energy Research Group (ERG) at the University of Illinois at Urbana-Champaign through the 1970s and early 1980s has recurring bouts of popularity. That research traced the flow of various energy types from nature to the final product or service, using modified economic input-output analysis. That information allowed for a comparison of alternative uses of products and services that delivered the same demand. The goal of the study was to identify the energy-conserving potential of the alternatives. Interest in that research has risen and fallen with the price of energy through three cycles now, with the current interest also encompassing materials conservation. Although the specific numerical results of this work are dated, the process by which the analysis was conducted creates, at least, a suggestion for future analysis in the arena of materials research. A review of the ERG history, including techniques pioneered for investigating the potential for energy conservation and some of the ancillary lessons learned along the way, may be of some use to those working on issues of materials conservation today. In the coming years, the most relevant research will include assessment of the socio-economic-ecological impact of technological materials conservation policies.

  9. Regeneration of tissues of the oral complex: current clinical trends and research advances.

    Science.gov (United States)

    Nguyen, Thomas T; Mui, Brennan; Mehrabzadeh, Mahsa; Chea, Yannie; Chaudhry, Zoya; Chaudhry, Kamran; Tran, Simon D

    2013-01-01

    Regenerative therapy in oral health care is limited by both the body's natural capacity for regeneration and the materials and methods currently available. Research on various aspects of regenerative therapy, such as tissue engineering and stem cell and gene therapy, has produced promising results. Compelling advances, ranging from the discovery and characterization of stem cell populations in oral tissue to the engineering and transplantation of whole tooth structures, could result in exciting new treatment methods for clinicians in the near future. In this review, we discuss the limitations of natural healing and regeneration of various tissues of the oral complex, including teeth, periodontium and salivary glands, and summarize current treatment methods for tissue damage as well as research advances in oral tissue regeneration.

  10. Where Is Current Research on Blockchain Technology?—A Systematic Review

    Science.gov (United States)

    Yli-Huumo, Jesse; Ko, Deokyoon; Park, Sooyong; Smolander, Kari

    2016-01-01

    Blockchain is a decentralized transaction and data management technology developed first for Bitcoin cryptocurrency. The interest in Blockchain technology has been increasing since the idea was coined in 2008. The reason for the interest in Blockchain is its central attributes that provide security, anonymity and data integrity without any third party organization in control of the transactions, and therefore it creates interesting research areas, especially from the perspective of technical challenges and limitations. In this research, we have conducted a systematic mapping study with the goal of collecting all relevant research on Blockchain technology. Our objective is to understand the current research topics, challenges and future directions regarding Blockchain technology from the technical perspective. We have extracted 41 primary papers from scientific databases. The results show that focus in over 80% of the papers is on Bitcoin system and less than 20% deals with other Blockchain applications including e.g. smart contracts and licensing. The majority of research is focusing on revealing and improving limitations of Blockchain from privacy and security perspectives, but many of the proposed solutions lack concrete evaluation on their effectiveness. Many other Blockchain scalability related challenges including throughput and latency have been left unstudied. On the basis of this study, recommendations on future research directions are provided for researchers. PMID:27695049

  11. Where Is Current Research on Blockchain Technology?-A Systematic Review.

    Science.gov (United States)

    Yli-Huumo, Jesse; Ko, Deokyoon; Choi, Sujin; Park, Sooyong; Smolander, Kari

    2016-01-01

    Blockchain is a decentralized transaction and data management technology developed first for Bitcoin cryptocurrency. The interest in Blockchain technology has been increasing since the idea was coined in 2008. The reason for the interest in Blockchain is its central attributes that provide security, anonymity and data integrity without any third party organization in control of the transactions, and therefore it creates interesting research areas, especially from the perspective of technical challenges and limitations. In this research, we have conducted a systematic mapping study with the goal of collecting all relevant research on Blockchain technology. Our objective is to understand the current research topics, challenges and future directions regarding Blockchain technology from the technical perspective. We have extracted 41 primary papers from scientific databases. The results show that focus in over 80% of the papers is on Bitcoin system and less than 20% deals with other Blockchain applications including e.g. smart contracts and licensing. The majority of research is focusing on revealing and improving limitations of Blockchain from privacy and security perspectives, but many of the proposed solutions lack concrete evaluation on their effectiveness. Many other Blockchain scalability related challenges including throughput and latency have been left unstudied. On the basis of this study, recommendations on future research directions are provided for researchers.

  12. Potential of nanotechnology as a delivery platform against tuberculosis: current research review.

    Science.gov (United States)

    Choudhary, S; Kusum Devi, V

    2015-03-28

    This review focusses on the current ongoing research in the field of tuberculosis comprising the resistant strains. It specifies a proper data analysis with results in concise form from areas gripping in: diagnostic nanotechnology, vaccine nanotechnology and the prime field of interest i.e., therapeutic nanotechnology. Primarily, therapeutic area recollects the research findings from advanced drug delivery (primary era) to the targeted drug delivery (modern era). The vaccine-based area derives the immune-specific targeting with enhanced emphasis on vaccine extraction and preparation of nanoparticles. Finally, the diagnostic area signifies the imaging techniques that may be employed in the diagnosis of TB. Not only that, there are some researches that emphasized on finding the comparable diagnostic differences between normal and resistant strains. With the advent of carbon nanotubes, metallic NPs, a newer hope has emerged out in diagnostic research, which may extend to therapeutic research applications too. Modifications of natural polymers, least or no use of organic solvents, size controlled NPs, optimized methodology, etc., are fields that need more effort to bypass toxicity. If above desired possibilities get the priority during research, it may lead to shift in the timeline towards much more oriented research. Copyright © 2015 Elsevier B.V. All rights reserved.

  13. 广西河湖水域岸线管理现状分析及建议%Current status analysis and suggestions for administration of river-lake shoreline and water area in Guangxi

    Institute of Scientific and Technical Information of China (English)

    王晓妮

    2013-01-01

    An introduction was made on the current status of river-lake shoreline and water area administration in Guangxi. The author analyzed the major problems and put forward suggestions for strengthening administration.%  介绍了广西河湖水域岸线管理现状,分析现阶段管理中存在的主要问题,并提出加强河湖水域及岸线管理的建议措施。

  14. White Paper on Multicarrier Excitation of Multipactor Breakdown: A Survey of Current Methods and Research Opportunities

    Science.gov (United States)

    2015-06-18

    AEROSPACE REPORT NO. TOR-2015-02548 White Paper on Multicarrier Excitation of Multipactor Breakdown: A Survey of Current Methods and...voltage phenomena where the verification power level is chosen such that the maximum instantaneous operational voltage in the component is excited . In...analysis methods under investigation for multicarrier excitation threshold prediction based on a survey of the research literature. In general, this

  15. MicroRNAs as Biomarkers for Psychiatric Conditions: A Review of Current Research

    Science.gov (United States)

    Hussain, Mariyah; Sreeram, Venkatesh

    2017-01-01

    Neural-derived exosomes can be used as diagnostic markers to screen for various psychiatric conditions. These intravenously injected exosomes carry the potential to cross the blood brain barrier and deliver miRNA molecules specifically to neurons, microglia, and oligodendrocytes in the brain, resulting in specific gene knockdown. Here the authors review and discuss the current research on microRNA molecules and the therapeutic roles they may potentially play in treating depression, bipolar disorder, and schizophrenia.

  16. Consultation and illness behaviour in response to symptoms: a comparison of models from different disciplinary frameworks and suggestions for future research directions.

    Science.gov (United States)

    Wyke, Sally; Adamson, Joy; Dixon, Diane; Hunt, Kate

    2013-06-01

    We all get ill and social scientific interest in how we respond - the study of illness behaviour - continues unabated. Existing models are useful, but have been developed and applied within disciplinary silos, resulting in wasted intellectual and empirical effort and an absence of accumulation of knowledge across disciplines. We present a critical review and detailed comparison of three process models of response to symptoms: the Illness Action Model, the Common Sense Model of the Self-Regulation of Health and Illness and the Network Episode Model. We suggest an integrated framework in which symptoms, responses and actions are simultaneously interpreted and evaluated in the light of accumulated knowledge and through interactions. Evaluation may be subconscious and is influenced by the extent to which the symptoms impose themselves, expectations of outcomes, the resources available and understanding of symptoms' salience and possible outcomes. Actions taken are part of a process of problem solving through which both individuals and their immediate social network seek to (re)achieve 'normality'. Response is also influenced by social structure (directly and indirectly), cultural expectations of health, the meaning of symptoms, and access to and understandings of the legitimate use of services. Changes in knowledge, in embodied state and in emotions can all be directly influential at any point. We do not underestimate the difficulty of operationalising an integrated framework at different levels of analysis. Attempts to do so will require us to move easily between disciplinary understandings to conduct prospective, longitudinal, research that uses novel methodologies to investigate response to symptoms in the context of affective as well as cognitive responses and interactions within social networks. While challenging such an approach would facilitate accumulation of knowledge across disciplines and enable movement beyond description to change in individual and

  17. JSC Advanced Curation: Research and Development for Current Collections and Future Sample Return Mission Demands

    Science.gov (United States)

    Fries, M. D.; Allen, C. C.; Calaway, M. J.; Evans, C. A.; Stansbery, E. K.

    2015-01-01

    Curation of NASA's astromaterials sample collections is a demanding and evolving activity that supports valuable science from NASA missions for generations, long after the samples are returned to Earth. For example, NASA continues to loan hundreds of Apollo program samples to investigators every year and those samples are often analyzed using instruments that did not exist at the time of the Apollo missions themselves. The samples are curated in a manner that minimizes overall contamination, enabling clean, new high-sensitivity measurements and new science results over 40 years after their return to Earth. As our exploration of the Solar System progresses, upcoming and future NASA sample return missions will return new samples with stringent contamination control, sample environmental control, and Planetary Protection requirements. Therefore, an essential element of a healthy astromaterials curation program is a research and development (R&D) effort that characterizes and employs new technologies to maintain current collections and enable new missions - an Advanced Curation effort. JSC's Astromaterials Acquisition & Curation Office is continually performing Advanced Curation research, identifying and defining knowledge gaps about research, development, and validation/verification topics that are critical to support current and future NASA astromaterials sample collections. The following are highlighted knowledge gaps and research opportunities.

  18. Medical Big Data for Research Use: Current Status and Related Issues.

    Science.gov (United States)

    Ishikawa, Koichi Benjamin

    2016-09-01

    Advances in the computerization of information and development of technology have mitigated restrictions on handling of a large amount of information. This has resulted in growth of expectations for the use of large-scale databases, or so-called "big data." This is also the case in the field of healthcare. Projects that involve building of the national receipt database (NDB) of medical fee bill (receipt) information and special health check-up information based on the Act on Assurance of Medical Care for Elderly People and the development of medical information databases have been pursued by the national government, and considerable attention has also been focused on researches conducted through the secondary uses of publicly collected data. Aside from these trends, there are numerous projects which collect diagnosis procedure combination (DPC) data to build large-scale databases for research purposes. Following to the ethics guidelines for epidemiologic studies, they collect and analyze anonymized DPC data from cooperating institutions. This communication concentrates on the use of DPC data, and outlines the scale of data currently available for research use. Examples on the use of DPC data will be shown for analysis on the current status of clinical practice from the microscopic perspective and macroscopic analysis of community medical care provision. Additionally, potential for extending studies to long-term outcomes research, limitations and issues related to the use of medical big data will also be discussed.

  19. Review of current interest and research in water hyacinth-based wastewater treatment

    Science.gov (United States)

    Markarian, R. K.; Balon, J. E.; Robinson, A. C.

    1977-01-01

    The status of activity in the user community for water hyacinth-based wastewater treatment was evaluated. The principal technique used was that of interviewing people who either (1) were known to be engaged in hyacinth research or development or (2) had made inquiry to NASA about hyacinth systems. About 40 non-research organizations and a similar number of research organizations were contacted. As a result of the interviews and a review of the relevant literature, it was concluded that hyacinth systems have the potential for providing a lower cost way for small cities to meet increasingly stringent effluent requirements. A limited amount of full-scale demonstration of hyacinth systems has been carried out during the past two years, but the yield of design data has been small. Several organizations are currently planning construction of experimental full-scale hyacinth-based wastewater treatment systems during 1977-1978.

  20. Unmanned aircraft systems in wildlife research: Current and future applications of a transformative technology

    Science.gov (United States)

    Christie, Katherine S.; Gilbert, Sophie L.; Brown, Casey L.; Hatfield, Michael; Hanson, Leanne

    2016-01-01

    Unmanned aircraft systems (UAS) – also called unmanned aerial vehicles (UAVs) or drones – are an emerging tool that may provide a safer, more cost-effective, and quieter alternative to traditional research methods. We review examples where UAS have been used to document wildlife abundance, behavior, and habitat, and illustrate the strengths and weaknesses of this technology with two case studies. We summarize research on behavioral responses of wildlife to UAS, and discuss the need to understand how recreational and commercial applications of this technology could disturb certain species. Currently, the widespread implementation of UAS by scientists is limited by flight range, regulatory frameworks, and a lack of validation. UAS are most effective when used to examine smaller areas close to their launch sites, whereas manned aircraft are recommended for surveying greater distances. The growing demand for UAS in research and industry is driving rapid regulatory and technological progress, which in turn will make them more accessible and effective as analytical tools.

  1. Qualitative ergonomics/human factors research in health care: Current state and future directions.

    Science.gov (United States)

    Valdez, Rupa Sheth; McGuire, Kerry Margaret; Rivera, A Joy

    2017-07-01

    The objective of this systematic review was to understand the current state of Ergonomics/Human Factors (E/HF) qualitative research in health care and to draw implications for future efforts. This systematic review identified 98 qualitative research papers published between January 2005 and August 2015 in the seven journals endorsed by the International Ergonomics Association with an impact factor over 1.0. The majority of the studies were conducted in hospitals and outpatient clinics, were focused on the work of formal health care professionals, and were classified as cognitive or organizational ergonomics. Interviews, focus groups, and observations were the most prevalent forms of data collection. Triangulation and data archiving were the dominant approaches to ensuring rigor. Few studies employed a formal approach to qualitative inquiry. Significant opportunities remain to enhance the use of qualitative research to advance systems thinking within health care. Copyright © 2017 Elsevier Ltd. All rights reserved.

  2. Constructed wetlands, 1991-2011: a review of research development, current trends, and future directions.

    Science.gov (United States)

    Zhi, Wei; Ji, Guodong

    2012-12-15

    This study explores a bibliometric approach to quantitatively evaluate global scientific constructed wetlands research, and statistically assess current trends, and future directions using the Science Citation Index Expanded (SCI-EXPANDED) database from 1991 to 2011. Articles referencing constructed wetlands were analyzed by accessing the following: publication language, output characteristics, publication performance by country and institution, author keywords, title words, and KeyWords Plus. Synthetically analyzing three keyword types, we concluded that the dominant constructed wetlands research hotspots from 1991 to 2011 included water, nutrients, plants, and flow. These four hotspots remained the most dominant research areas throughout our study period, and are predicted to remain the top research emphases in the near future. "Soil" also exhibited a notable increase since 2005, and is likely to become another notable area of research interest in the future. "Phytoremediation" and "horizontal" were not identified in 1991-1995, but exhibited marked increases from 136th (0.5%) and 169th (0.7%) in 1996-2000, to 9th (3.8%) and 11th (4.3%) in 2006-2011, respectively. Therefore, given the heightened attention during the last 15 years, these topics are likely to become a primary research focus in upcoming years.

  3. Wave-current interactions at the FloWave Ocean Energy Research Facility

    Science.gov (United States)

    Noble, Donald; Davey, Thomas; Steynor, Jeffrey; Bruce, Tom; Smith, Helen; Kaklis, Panagiotis

    2015-04-01

    Physical scale model testing is an important part of the marine renewable energy development process, allowing the study of forces and device behaviour in a controlled environment prior to deployment at sea. FloWave is a new state-of-the-art ocean energy research facility, designed to provide large scale physical modelling services to the tidal and wave sector. It has the unique ability to provide complex multi-directional waves that can be combined with currents from any direction in the 25m diameter circular tank. The facility is optimised for waves around 2s period and 0.4m height, and is capable of generating currents upwards of 1.6m/s. This offers the ability to model metocean conditions suitable for most renewable energy devices at a typical scale of between 1:10 and 1:40. The test section is 2m deep, which can be classed as intermediate-depth for most waves of interest, thus the full dispersion equation must be solved as the asymptotic simplifications do not apply. The interaction between waves and currents has been studied in the tank. This has involved producing in the tank sets of regular waves, focussed wave groups, and random sea spectra including multi-directional sea states. These waves have been both inline-with and opposing the current, as well as investigating waves at arbitrary angles to the current. Changes in wave height and wavelength have been measured, and compared with theoretical results. Using theoretical wave-current interaction models, methods have been explored to "correct" the wave height in the central test area of the tank when combined with a steady current. This allows the wave height with current to be set equal to that without a current. Thus permitting, for example, direct comparison of device motion response between tests with and without current. Alternatively, this would also permit a specific wave height and current combination to be produced in the tank, reproducing recorded conditions at a particular site of interest. The

  4. Guiyang modern logistics industry and regional economic coordinated development of the Current Situation and Suggestions%贵阳市现代物流业与区域经济协调发展现状及对策建议

    Institute of Scientific and Technical Information of China (English)

    曾方俊

    2012-01-01

    根据现代物流业与区域经济协调发展的重要性和内在机理,对贵阳市现代物流业与区域经济发展现状进行调研,针对存在的问题,提出了相关对策建议。%According to the importance of the modem logistics industry and the coordinated development of regional economy and the internal mechanism of Guiyang City, the modem logistics industry and regional economic development research, development and put forward relevant suggestions for possible problems.

  5. An Official American Thoracic Society Research Statement: Current Challenges Facing Research and Therapeutic Advances in Airway Remodeling.

    Science.gov (United States)

    Prakash, Y S; Halayko, Andrew J; Gosens, Reinoud; Panettieri, Reynold A; Camoretti-Mercado, Blanca; Penn, Raymond B

    2017-01-15

    Airway remodeling (AR) is a prominent feature of asthma and other obstructive lung diseases that is minimally affected by current treatments. The goals of this Official American Thoracic Society (ATS) Research Statement are to discuss the scientific, technological, economic, and regulatory issues that deter progress of AR research and development of therapeutics targeting AR and to propose approaches and solutions to these specific problems. This Statement is not intended to provide clinical practice recommendations on any disease in which AR is observed and/or plays a role. An international multidisciplinary group from within academia, industry, and the National Institutes of Health, with expertise in multimodal approaches to the study of airway structure and function, pulmonary research and clinical practice in obstructive lung disease, and drug discovery platforms was invited to participate in one internet-based and one face-to-face meeting to address the above-stated goals. Although the majority of the analysis related to AR was in asthma, AR in other diseases was also discussed and considered in the recommendations. A literature search of PubMed was performed to support conclusions. The search was not a systematic review of the evidence. Multiple conceptual, logistical, economic, and regulatory deterrents were identified that limit the performance of AR research and impede accelerated, intensive development of AR-focused therapeutics. Complementary solutions that leverage expertise of academia and industry were proposed to address them. To date, numerous factors related to the intrinsic difficulty in performing AR research, and economic forces that are disincentives for the pursuit of AR treatments, have thwarted the ability to understand AR pathology and mechanisms and to address it clinically. This ATS Research Statement identifies potential solutions for each of these factors and emphasizes the importance of educating the global research community as to the

  6. Using ASM Podcasts to Excite Undergraduate Students about Current Microbiological Research

    Directory of Open Access Journals (Sweden)

    Stacey E. Lettini

    2014-08-01

    Full Text Available Innovative technology is often used as a mechanism to engage students in and out of the classroom and can be used to increase critical thinking skills. Podcasts are an excellent way to introduce students to current topics and research in microbiology. The American Society for Microbiology (ASM produces three podcasts that are microbiologically focused: This Week in Microbiology (TWiM, This Week in Parasitology (TWiP, and This Week in Virology (TWiV. These podcasts are usually presented in a manner similar to a journal club, as the presenters regularly invite guests to discuss current research papers. Since students often find reading scientific literature difficult and get bogged down in the details rather than seeing the over-arching purpose of a paper, these podcasts have been used in a General Microbiology course to introduce recent research articles. The students were first assigned an original research article to read and review, and they were asked to generate questions pertaining to things they did not understand. Next, students listened to the corresponding podcast that discussed the article and used it to answer their questions. This was followed by a classroom discussion of the article and the podcast. The ASM podcast helped to demystify original research by providing details of the experimental design and presentation of the results in a language that is more casual and relatable. Students demonstrated greater critical thinking and comprehension of microbiology literature after listening to the podcast. This activity can be used in a variety of courses in the biology curriculum.

  7. Current research and potential applications of the Concealed Information Test: An overview

    Directory of Open Access Journals (Sweden)

    Gershon eBen-Shakhar

    2012-09-01

    Full Text Available Research interest in psychophysiological detection of deception has significantly increased since the September 11 terror attack in the USA. In particular, the Concealed Information Test (CIT, designed to detect memory traces that can connect suspects to a certain crime, has been extensively studied. In this paper I will briefly review several psychophysiological detection paradigms that have been studied, with a focus on the CIT. The theoretical background of the CIT, its strength and weaknesses, its potential applications as well as research finings related to its validity, (based on a recent mata-analytic study, will be discussed. Several novel research directions, with a focus on factors that may affect CIT detection in realistic settings (e.g., memory for crime details; the effect of emotional stress during crime execution will be described. Additionally, research focusing on mal-intentions and attempts to detect terror networks using information gathered from groups of suspects using both the standard CIT and the searching CIT will be reviewed. Finally, implications of current research to the actual application of the CIT will be discussed and several recommendations that can enhance the use of the CIT will be made.

  8. At the crossroads of anthropology and epidemiology: current research in cultural psychiatry in the UK.

    Science.gov (United States)

    Dein, Simon; Bhui, Kamaldeep Singh

    2013-12-01

    Cultural psychiatry research in the UK comprises a broad range of diverse methodologies, academic disciplines, and subject areas. Methodologies range from epidemiological to anthropological/ethnographic to health services research; mixed methods research is becoming increasingly popular, as are public health and health promotional topics. After briefly outlining the history of cultural psychiatry in the UK we will discuss contemporary research. Prominent themes include: the epidemiology of schizophrenia among Africans/Afro-Caribbeans, migration and mental health, racism and mental health, cultural identity, pathways to care, explanatory models of mental illness, cultural competence, and the subjective experiences of healthcare provision among specific ethnic groups such as Bangladeshis and Pakistanis. Another strand of research that is attracting increasing academic attention focuses upon the relationship between religion, spirituality, and mental health, in particular, the phenomenology of religious experience and its mental health ramifications, as well as recent work examining the complex links between theology and psychiatry. The paper ends by appraising the contributions of British cultural psychiatrists to the discipline of cultural psychiatry and suggesting promising areas for future research.

  9. Current Realities and Future Possibilities: Language and science literacy—empowering research and informing instruction

    Science.gov (United States)

    Yore, Larry D.; Treagust, David F.

    2006-02-01

    In this final article, we briefly review and synthesize the science and language research and practice that arose from the current literature and presentations at an international conference, referred to as the first “Island Conference”. We add to the synthesis of the articles the conference deliberations and on-going discussions of the field and also offer our views as to how such contributions can take place. These central issues—the definition of science literacy; the models of learning, discourse, reading, and writing and their underlying pedagogical assumptions; the roles of discourse in doing, teaching, and learning science; and the demands on teacher education and professional development in the current reforms in language and science education—provide points of departure for discussion of four possible new considerations to research in this field of endeavour that could contribute to a broader and productive scholarship and deeper and enriched understanding of both teaching and learning. These considerations, each from well-established fields of research literature, are the need to develop support for a contemporary view of science literacy, the role of metacognition in science learning generally, the role of multiple representations in knowledge building and science literacy, and the need for more focused teacher education and professional development programmes.

  10. A comparative study: the impact of different lipid extraction methods on current microalgal lipid research.

    Science.gov (United States)

    Li, Yan; Ghasemi Naghdi, Forough; Garg, Sourabh; Adarme-Vega, Tania Catalina; Thurecht, Kristofer J; Ghafor, Wael Abdul; Tannock, Simon; Schenk, Peer M

    2014-01-24

    Microalgae cells have the potential to rapidly accumulate lipids, such as triacylglycerides that contain fatty acids important for high value fatty acids (e.g., EPA and DHA) and/or biodiesel production. However, lipid extraction methods for microalgae cells are not well established, and there is currently no standard extraction method for the determination of the fatty acid content of microalgae. This has caused a few problems in microlagal biofuel research due to the bias derived from different extraction methods. Therefore, this study used several extraction methods for fatty acid analysis on marine microalga Tetraselmis sp. M8, aiming to assess the potential impact of different extractions on current microalgal lipid research. These methods included classical Bligh & Dyer lipid extraction, two other chemical extractions using different solvents and sonication, direct saponification and supercritical CO₂ extraction. Soxhlet-based extraction was used to weigh out the importance of solvent polarity in the algal oil extraction. Coupled with GC/MS, a Thermogravimetric Analyser was used to improve the quantification of microalgal lipid extractions. Among these extractions, significant differences were observed in both, extract yield and fatty acid composition. The supercritical extraction technique stood out most for effective extraction of microalgal lipids, especially for long chain unsaturated fatty acids. The results highlight the necessity for comparative analyses of microalgae fatty acids and careful choice and validation of analytical methodology in microalgal lipid research.

  11. Radiology Research in Quality and Safety: Current Trends and Future Needs.

    Science.gov (United States)

    Zygmont, Matthew E; Itri, Jason N; Rosenkrantz, Andrew B; Duong, Phuong-Anh T; Mankowski Gettle, Lori; Mendiratta-Lala, Mishal; Scali, Elena P; Winokur, Ronald S; Probyn, Linda; Kung, Justin W; Bakow, Eric; Kadom, Nadja

    2017-03-01

    Promoting quality and safety research is now essential for radiology as reimbursement is increasingly tied to measures of quality, patient safety, efficiency, and appropriateness of imaging. This article provides an overview of key features necessary to promote successful quality improvement efforts in radiology. Emphasis is given to current trends and future opportunities for directing research. Establishing and maintaining a culture of safety is paramount to organizations wishing to improve patient care. The correct culture must be in place to support quality initiatives and create accountability for patient care. Focused educational curricula are necessary to teach quality and safety-related skills and behaviors to trainees, staff members, and physicians. The increasingly complex healthcare landscape requires that organizations build effective data infrastructures to support quality and safety research. Incident reporting systems designed specifically for medical imaging will benefit quality improvement initiatives by identifying and learning from system errors, enhancing knowledge about safety, and creating safer systems through the implementation of standardized practices and standards. Finally, validated performance measures must be developed to accurately reflect the value of the care we provide for our patients and referring providers. Common metrics used in radiology are reviewed with focus on current and future opportunities for investigation. Copyright © 2017 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.

  12. What Does Research Suggest about the Teaching and Learning of Introductory Statistics at the College Level? A Review of the Literature

    Science.gov (United States)

    Zieffler, Andrew; Garfield, Joan; Alt, Shirley; Dupuis, Danielle; Holleque, Kristine; Chang, Beng

    2008-01-01

    Since the first studies on the teaching and learning of statistics appeared in the research literature, the scholarship in this area has grown dramatically. Given the diversity of disciplines, methodology, and orientation of the studies that may be classified as "statistics education research," summarizing and critiquing this body of work for…

  13. Towards Current Profile Control in ITER: Potential Approaches and Research Needs

    Science.gov (United States)

    Schuster, E.; Barton, J. E.; Wehner, W. P.

    2014-10-01

    Many challenging plasma control problems still need to be addressed in order for the ITER Plasma Control System (PCS) to be able to successfully achieve the ITER project goals. For instance, setting up a suitable toroidal current density profile is key for one possible advanced scenario characterized by noninductive sustainment of the plasma current and steady-state operation. The nonlinearity and high dimensionality exhibited by the plasma demand a model-based current-profile control synthesis procedure that can accommodate this complexity through embedding the known physics within the design. The development of a model capturing the dynamics of the plasma relevant for control design enables not only the design of feedback controllers for regulation or tracking but also the design of optimal feedforward controllers for a systematic model-based approach to scenario planning, the design of state estimators for a reliable real-time reconstruction of the plasma internal profiles based on limited and noisy diagnostics, and the development of a fast predictive simulation code for closed-loop performance evaluation before implementation. Progress towards control-oriented modeling of the current profile evolution and associated control design has been reported following both data-driven and first-principles-driven approaches. An overview of these two approaches will be provided, as well as a discussion on research needs associated with each one of the model applications described above. Supported by the US Department of Energy under DE-SC0001334 and DE-SC0010661.

  14. Large-Eddy Simulation: Current Capabilities, Recommended Practices, and Future Research

    Science.gov (United States)

    Georgiadis, Nicholas J.; Rizzetta, Donald P.; Fureby, Christer

    2009-01-01

    This paper presents the results of an activity by the Large Eddy Simulation (LES) Working Group of the AIAA Fluid Dynamics Technical Committee to (1) address the current capabilities of LES, (2) outline recommended practices and key considerations for using LES, and (3) identify future research needs to advance the capabilities and reliability of LES for analysis of turbulent flows. To address the current capabilities and future needs, a survey comprised of eleven questions was posed to LES Working Group members to assemble a broad range of perspectives on important topics related to LES. The responses to these survey questions are summarized with the intent not to be a comprehensive dictate on LES, but rather the perspective of one group on some important issues. A list of recommended practices is also provided, which does not treat all aspects of a LES, but provides guidance on some of the key areas that should be considered.

  15. Current trends in research and clinical issues in the study of personality and its disorders

    DEFF Research Database (Denmark)

    Simonsen, Erik; Sørensen, Per; Pedersen, Liselotte

    2014-01-01

    lecture (Simonsen), a young researchers' symposium (Hopwood, Sharp, and Kaess), and special lectures on the Danish philosopher Soeren Kierkegaard and the poet Hans Christian Andersen. In this article we will survey the presentations and highlight the important issues in order to underline the current......The International Society for the Study of Personality Disorders (ISSPD) celebrated its 25th anniversary in September 2013 in Copenhagen and commemorated the First International Congress at the same site. The overall theme of the congress was "Bridging Personality and Psychopathology: The Person...... Behind the Illness." More than 400 abstracts were submitted, and the program included 8 keynote presentations, 18 invited symposia, a debate on current controversial issues in the classification of personality disorders (Fossati, Tyrer, Livesley, and Krueger), an ISSPD award lecture (Silk), a jubilee...

  16. Problems and Suggestions of Hospital Scientific Research Files Management%医院科研档案管理存在的的问题与建议

    Institute of Scientific and Technical Information of China (English)

    胡桂周; 吴志华; 鲁鸿; 钱毅; 陈超

    2013-01-01

    Scientific research files are very important in scientific research .The scientific research management also has high requirements to scien-tific research files .But scientific research files management also has problems now .We should regulate scientific research files management ,complete management system ,increase input ,and improve the management professional knowledge level of administrative staffs ,fit out complete file tools ,and increase the utilization of archives to provide better service for the scientific research work .%  科研档案对科研工作具有重要性,科研工作管理对科研档案也有很高的要求,发挥档案潜在的利用价值日趋常态化。但现有的科研档案管理还存在问题,我们应该规范科研档案管理、完善管理制度、加大投入力度、提高管理人员专业知识水平、配备齐全档案工具以及加大档案利用率,才能更好地服务于科研工作。

  17. An Overview of Current Capabilities and Research Activities in the Airspace Operations Laboratory at NASA Ames Research Center

    Science.gov (United States)

    Prevot, Thomas; Smith, Nancy M.; Palmer, Everett; Callantine, Todd; Lee, Paul; Mercer, Joey; Homola, Jeff; Martin, Lynne; Brasil, Connie; Cabrall, Christopher

    2014-01-01

    The Airspace Operations Laboratory at NASA Ames conducts research to provide a better understanding of roles, responsibilities, and requirements for human operators and automation in future air traffic management (ATM) systems. The research encompasses developing, evaluating, and integrating operational concepts and technologies for near-, mid-, and far-term air traffic operations. Current research threads include efficient arrival operations, function allocation in separation assurance and efficient airspace and trajectory management. The AOL has developed powerful air traffic simulation capabilities, most notably the Multi Aircraft Control System (MACS) that is used for many air traffic control simulations at NASA and its partners in government, academia and industry. Several additional NASA technologies have been integrated with the AOL's primary simulation capabilities where appropriate. Using this environment, large and small-scale system-level evaluations can be conducted to help make near-term improvements and transition NASA technologies to the FAA, such as the technologies developed under NASA's Air Traffic Management Demonstration-1 (ATD-1). The AOL's rapid prototyping and flexible simulation capabilities have proven a highly effective environment to progress the initiation of trajectory-based operations and support the mid-term implementation of NextGen. Fundamental questions about accuracy requirements have been investigated as well as realworld problems on how to improve operations in some of the most complex airspaces in the US. This includes using advanced trajectory-based operations and prototype tools for coordinating arrivals to converging runways at Newark airport and coordinating departures and arrivals in the San Francisco and the New York metro areas. Looking beyond NextGen, the AOL has started exploring hybrid human/automation control strategies as well as highly autonomous operations in the air traffic control domain. Initial results

  18. Third-generation biofuels: current and future research on microalgal lipid biotechnology

    Directory of Open Access Journals (Sweden)

    Li-Beisson Yonghua

    2013-11-01

    Full Text Available One pressing issue faced by modern societies is to develop renewable energy for transportation. Microalgal biomass offers an attractive solution due to its high (annual surface biomass productivity, efficient conversion of solar energy into chemical energy and the ability to grow on non-agricultural land. Despite these considerable advantages, microalgal biofuels are not yet commercially sustainable. Major challenges lie in improving both cultivation technologies and microalgal strains. A microalgal crop species is yet to emerge. In this review, we focus on researches aiming at understanding and harnessing lipid metabolism in microalgae in view of producing lipid-based biofuels such as biodiesel. Current biotechnological challenges and key progresses made in the development of algal models, genetic tools and lipid metabolic engineering strategies are reviewed. Possible future research directions to increase oil yields in microalgae are also highlighted.

  19. Bridging prediction and attention in current research on perception and action.

    Science.gov (United States)

    Schröger, Erich; Kotz, Sonja A; SanMiguel, Iria

    2015-11-11

    Prediction and attention are fundamental brain functions in the service of perception and action. Theories on prediction relate to neural (mental) models inferring about (present or future) sensory or action-related information, whereas theories of attention are about the control of information flow underlying perception and action. Both concepts are related and not always clearly distinguishable. The special issue includes current research on prediction and attention in various subfields of perception and action. It especially considers interactions between predictive and attentive processes, which constitute a newly emerging and highly interesting field of research. As outlined in this editorial, the contributions in this special issue allow specifying as well as bridging concepts on prediction and attention. The joint consideration of prediction and attention also reveals common functional principles of perception and action.

  20. Research on Proximity Magnetic Field Influence in Measuring Error of Active Electronic Current Transformers

    Directory of Open Access Journals (Sweden)

    Wu Weijiang

    2016-01-01

    Full Text Available The principles of the active electronic current transformer (ECT are introduced, and the mechanism of how a proximity magnetic field can influence the measuring of errors is analyzed from the perspective of the sensor section of the ECT. The impacts on active ECTs created by three-phase proximity magnetic field with invariable distance and variable distance are simulated and analyzed. The theory and simulated analysis indicate that the active ECTs are sensitive to proximity magnetic field under certain conditions. According to simulated analysis, a product structural design and the location of transformers at substation sites are suggested for manufacturers and administration of power supply, respectively.

  1. An Official American Thoracic Society Research Statement: Current Understanding and Future Research Needs in Tobacco Control and Treatment.

    Science.gov (United States)

    Leone, Frank T; Carlsen, Kai-Hakon; Folan, Patricia; Latzka, Karen; Munzer, Alfred; Neptune, Enid; Pakhale, Smita; Sachs, David P L; Samet, Jonathan; Upson, Dona; White, Alexander

    2015-08-01

    Since the mid-20th century, the scientific community has substantially improved its understanding of the worldwide tobacco epidemic. Although significant progress has been made, the sheer enormity and scope of the global problem put it on track to take a billion lives this century. Curbing the epidemic will require maximizing the impact of proven tools as well as the development of new, breakthrough methods to help interrupt the spread of nicotine addiction and reduce the downstream morbidity. Members of the Tobacco Action Committee of the American Thoracic Society queried bibliographic databases, including Medline, Embase, and the Cochrane Collaborative, to identify primary sources and reviews relevant to the epidemic. Exploded search terms were used to identify evidence, including tobacco, addiction, smoking, cigarettes, nicotine, and smoking cessation. Evidence was consolidated into three thematic areas: (1) determinants of risk, (2) maternal-fetal exposure, and (3) current tobacco users. Expert panel consensus regarding current gaps in understanding and recommendations for future research priorities was generated through iterative discussion. Although much has been accomplished, significant gaps in understanding remain. Implementation often lags well behind insight. This report identifies a number of investigative opportunities for significantly reducing the toll of tobacco use, including: (1) the need for novel, nonlinear models of population-based disease control; (2) refinement of "real-world" models of clinical intervention in trial design; and (3) understanding of mechanisms by which intrauterine smoke exposure may lead to persistent, tobacco-related chronic disease. In the coming era of tobacco research, pooled talent from multiple disciplines will be required to further illuminate the complex social, environmental and biological codeterminants of tobacco dependence.

  2. Ocean Science for Decision-Making: Current Activities of the National Research Council's Ocean Studies Board

    Science.gov (United States)

    Roberts, S.; Glickson, D.; Mengelt, C.; Forrest, S.; Waddell, K.

    2012-12-01

    The National Research Council is a private, nonprofit organization chartered by Congress in 1916 as an expansion of the U.S. National Academy of Sciences. Its mission is to improve the use of science in government decision making and public policy, increase public understanding, and promote the acquisition and dissemination of knowledge in matters involving science, engineering, technology, and health. Within the National Research Council, the Ocean Studies Board (OSB) mission is to explore the science, policies, and infrastructure needed to understand, manage, and conserve coastal and marine environments and resources. OSB undertakes studies and workshops on emerging scientific and policy issues at the request of federal agencies, Congress, and others; provides program reviews and guidance; and facilitates communication on oceanographic issues among different sectors. OSB also serves as the U.S. National Committee to the international, nongovernmental Scientific Committee on Oceanic Research (SCOR). OSB has produced reports on a wide range of topics of interest to researchers and educators, the federal government, the non-profit sector, and industry. Recent reports have focused on ecosystem services in the Gulf of Mexico after the Deepwater Horizon oil spill, sea level rise on the U.S. west coast, scientific ocean drilling needs and accomplishments, requirements for sustained ocean color measurements, critical infrastructure for ocean research, tsunami warning and preparedness, ocean acidification, and marine and hydrokinetic power resource assessments. Studies that are currently underway include responding to oil spills in the Arctic, evaluating the effectiveness of fishery stock rebuilding plans, and reviewing the National Ocean Acidification Research Plan. OSB plays an important role in helping create policy decisions and disseminating important information regarding various aspects of ocean science.

  3. "Thank you for your critical comments and helpful suggestions": compliance and conflict in authors' replies to referees' comments in peer reviews of scientific research papers

    Directory of Open Access Journals (Sweden)

    Hugh Gosden

    2001-04-01

    Full Text Available Peer reviews of research papers submitted to journals are an "occluded" genre (Swales, 1996 - referees are usually anonymous and the confidential reports themselves are not part of the official record of research publication. Thus, compared to the published, readily available genres of the academy, there are few opportunities to study gatekeeping discourse such as peer reviews, nor are there many opportunities for novice researchers to practice framing appropriate and effective point-by-point replies to criticisms. This paper is part of a study based on the analysis and functional description of comments from a corpus of referees' reports and authors' replies. The data highlight the importance of authors being able to recognize and interpret the relative interactional/interpersonal vs. technical/ideational orientation of requested revisions, in order to revise successfully their papers after peer review. Research on publication productivity in the sciences has emphasized the importance of early productivity as a strong predictor of future publication (Fox, 1983. When young scientists take up their first academic position, publication levels are initially more affected by the productivity of the pre-doctoral years than by the prestige of the new department and institution. In a "reinforcing process of advantage" (Fox, 1983:293, those who have published early will often continue to do so for several years until the supportive research environment of their present location will more strongly affect continued productivity.

  4. Modified Vaccinia Virus Ankara: History, Value in Basic Research, and Current Perspectives for Vaccine Development.

    Science.gov (United States)

    Volz, A; Sutter, G

    2017-01-01

    Safety tested Modified Vaccinia virus Ankara (MVA) is licensed as third-generation vaccine against smallpox and serves as a potent vector system for development of new candidate vaccines against infectious diseases and cancer. Historically, MVA was developed by serial tissue culture passage in primary chicken cells of vaccinia virus strain Ankara, and clinically used to avoid the undesirable side effects of conventional smallpox vaccination. Adapted to growth in avian cells MVA lost the ability to replicate in mammalian hosts and lacks many of the genes orthopoxviruses use to conquer their host (cell) environment. As a biologically well-characterized mutant virus, MVA facilitates fundamental research to elucidate the functions of poxvirus host-interaction factors. As extremely safe viral vectors MVA vaccines have been found immunogenic and protective in various preclinical infection models. Multiple recombinant MVA currently undergo clinical testing for vaccination against human immunodeficiency viruses, Mycobacterium tuberculosis or Plasmodium falciparum. The versatility of the MVA vector vaccine platform is readily demonstrated by the swift development of experimental vaccines for immunization against emerging infections such as the Middle East Respiratory Syndrome. Recent advances include promising results from the clinical testing of recombinant MVA-producing antigens of highly pathogenic avian influenza virus H5N1 or Ebola virus. This review summarizes our current knowledge about MVA as a unique strain of vaccinia virus, and discusses the prospects of exploiting this virus as research tool in poxvirus biology or as safe viral vector vaccine to challenge existing and future bottlenecks in vaccinology.

  5. Synergistic effects of Chinese herbal medicine: a comprehensive review of methodology and current research

    Directory of Open Access Journals (Sweden)

    Xian Zhou

    2016-07-01

    Full Text Available Traditional Chinese medicine is an important part of primary health care in Asian countries that has utilised complex herbal formulations (consisting 2 or more medicinal herbs for treating diseases over thousands of years. There seems to be a general assumption that the synergistic therapeutic effects of Chinese herbal medicine derive from the complex interactions between the multiple bioactive components within the herbs and/or herbal formulations. However, evidence to support these synergistic effects remains weak and controversial due to several reasons, including the very complex nature of Chinese herbal medicine, misconceptions about synergy, methodological challenges to study design. In this review, we clarify the definition of synergy, identify common errors in synergy research and describe current methodological approaches to test for synergistic interaction. We discuss the strengthen and weakness of these models in the context of Chinese herbal medicine and summarise the current status of synergy research in CHM. Despite the availability of some scientific data to support the synergistic effects of multi-herbal and/or herb-drug combinations, the level of evidence remains low and the clinical relevancy of most of these findings is undetermined. There remain significant challenges in the development of suitable methods for synergistic studies of complex herbal combinations.

  6. Bringing appraisal theory to environmental risk perception: a review of conceptual approaches of the past 40 years and suggestions for future research

    NARCIS (Netherlands)

    Keller, Carmen; Bostrom, Ann; Kuttschreuter, M.; Savadori, Lucia; Spence, Alexia; White, Mathew

    2012-01-01

    An intensive program of 40 years of research has produced various conceptual cognitive and affective approaches to environmental risk perception. In this short review of the most relevant conceptual approaches, appraisal theory is presented as a useful means of integrating cognitive and affective

  7. [Requirements for quality indicators. The relevance of current developments in outcomes research for quality management].

    Science.gov (United States)

    Schmitt, Jochen; Petzold, Thomas; Eberlein-Gonska, Maria; Neugebauer, Edmund A M

    2013-01-01

    The assessment of the health state in patients and changes in their health state for the purpose of diagnosis, prognosis and monitoring of treatment response plays a central role in clinical practice. Quality criteria for measurements in medicine include validity, reliability, responsiveness, interpretability, and feasibility. High-quality measurement instruments are a prerequisite for evidence-based medicine. Therefore, international outcomes research groups have developed methods for quality assurance and for the standardisation of measurement instruments. Quality indicators are instruments to measure the quality of care. Due to the increasing relevance of quality assessment for all stakeholders in healthcare and due to the political intention to draw relevant conclusions from the assessment of the quality of care, quality indicators must at least meet the same high standards that are required for clinical trial end points. However, independent researchers and clinicians do not engage in the validation and standardisation of quality indicators in Germany; currently, only the AQUA institute (as assigned by the German GBA) deals with this important issue. Current activities concerning the validation of quality indicators do not meet the requirements of evidence-based healthcare. This is a critical barrier to achieving the political goals of quality medicine. Therefore, the authors propose a multi-step, multi-professional, evidence-driven and evidence-generating consensus process on the basis of established methods of outcomes research for the advancement of quality assessment with quality indicators in Germany. All relevant stakeholders should participate in this process. Copyright © 2013. Published by Elsevier GmbH.

  8. Clinical evaluations for transfer of juveniles to criminal court: current practices and future research.

    Science.gov (United States)

    Kruh, I P; Brodsky, S L

    1997-01-01

    Completing clinical evaluations of juveniles considered for transfer to criminal court requires specialized expertise. However, there is little empirical foundation upon which they can be based. Within each of the three major evaluation domains (amenability to treatment, risk for future violence, and sophistication/maturity), we ask the following questions: a) Can forensic examiners properly assess this area, and if so using what tools?; b) How can social science research clarify the transfer evaluation, particularly as it is impacted by systems issues?; and c) How should the evaluation be structured? In doing so, we review clinical suggestions for completing these evaluations and identify pertinent research directions. A number of general issues specific to these evaluations are also discussed.

  9. Frontier Science in the Polar Regions: Current Activities of the Polar Research Board

    Science.gov (United States)

    Brown, L. M.

    2011-12-01

    The National Academies (the umbrella term for the National Academy of Sciences, National Academy of Engineering, Institute of Medicine, and National Research Council) is a private, nonprofit organization chartered by Congress in 1863. The Polar Research Board (PRB) is the focal point within the Academies for providing advice on issues related to the Arctic, Antarctic, and cold regions in general. Tasks within the PRB mission include: providing a forum for the polar science community to address research needs and policy issues; conducting studies and workshops on emerging scientific and policy issues in response to requests from federal agencies and others; providing program reviews, guidance, and assessments of priorities; and facilitating communication on polar issues among academia, industry, and government. The PRB also serves as the US National Committee to two international, nongovernmental polar science organizations: the Scientific Committee on Antarctic Research (SCAR) and the International Arctic Science Committee (IASC). The polar regions are experiencing rapid changes in environment and climate, and the PRB has a number of completed and ongoing studies that will enhance scientific understanding of these issues. This poster will illustrate current PRB activities as well as results from two recently released reports: Frontiers in Understanding Climate Change and Polar Ecosystems and Future Science Opportunities in Antarctica and the Southern Ocean. In the former, a set of frontier research questions are developed to help scientists understand the impacts of climate change on polar ecosystems. The report builds on existing knowledge of climate change impacts and highlights the next big topics to be addressed in the coming decades. In addition, a number of methods and technologies are identified that will be useful to advance future research in polar ecosystem science. In the latter, changes to important science conducted on Antarctica and the surrounding

  10. Topics in Current Science Research: Closing the Achievement Gap for Under Resourced Students of Color

    Science.gov (United States)

    Loya Villalpando, Alvaro; Daal, Miguel; Phipps, Arran; Speller, Danielle; Sadoulet, Bernard; Winheld, Rachel; Cryogenic Dark Matter Search Collaboration

    2015-04-01

    Topics in Current Science Research (TCSR) is a five-week summer course offered at the University of California, Berkeley through a collaboration between the Level Playing Field Institute's Summer Math and Science Honors Academy (SMASH) Program and the Cryogenic Dark Matter Search (CDMS) group at UC Berkeley. SMASH is an academic enrichment program geared towards under-resourced, high school students of color. The goals of the course are to expand the students' conception of STEM, to teach the students that science is a method of inquiry and not just a collection of facts that are taught in school, and to expose the scholars to critical thinking within a scientific setting. The course's curriculum engages the scholars in hands-on scientific research, project proposal writing, and presentation of their scientific work to their peers as well as to a panel of UC Berkeley scientists. In this talk, we describe the course and the impact it has had on previous scholars, we discuss how the course's pedagogy has evolved over the past 10 years to enhance students' perception and understanding of science, and we present previous participants' reflections and feedback about the course and its success in providing high school students a genuine research experience at the university level.

  11. Overview of current capabilities and research and technology developments for planetary protection

    Science.gov (United States)

    Frick, Andreas; Mogul, Rakesh; Stabekis, Pericles; Conley, Catharine A.; Ehrenfreund, Pascale

    2014-07-01

    The pace of scientific exploration of our solar system provides ever-increasing insights into potentially habitable environments, and associated concerns for their contamination by Earth organisms. Biological and organic-chemical contamination has been extensively considered by the COSPAR Panel on Planetary Protection (PPP) and has resulted in the internationally recognized regulations to which spacefaring nations adhere, and which have been in place for 40 years. The only successful Mars lander missions with system-level “sterilization” were the Viking landers in the 1970s. Since then different cleanliness requirements have been applied to spacecraft based on their destination, mission type, and scientific objectives. The Planetary Protection Subcommittee of the NASA Advisory Council has noted that a strategic Research & Technology Development (R&TD) roadmap would be very beneficial to encourage the timely availability of effective tools and methodologies to implement planetary protection requirements. New research avenues in planetary protection for ambitious future exploration missions can best be served by developing an over-arching program that integrates capability-driven developments with mission-driven implementation efforts. This paper analyzes the current status concerning microbial reduction and cleaning methods, recontamination control and bio-barriers, operational analysis methods, and addresses concepts for human exploration. Crosscutting research and support activities are discussed and a rationale for a Strategic Planetary Protection R&TD Roadmap is outlined. Such a roadmap for planetary protection provides a forum for strategic planning and will help to enable the next phases of solar system exploration.

  12. Current Trends and Research Challenges in Spectrum-Sensing for Cognitive Radios

    Directory of Open Access Journals (Sweden)

    Roopali Garg

    2016-07-01

    Full Text Available The ever increasing demand of wireless communication systems has led to search of suitable spectrum bands for transmission of data. The research in the past has revealed that radio spectrum is under-utilized in most of the scenarios. This prompted the scientist to seek a solution to utilize the spectrum efficiently. Cognitive Radios provided an answer to the problem by sensing the idle (licensed bands and allowing (secondary users to transmit in these idle spaces. Spectrum sensing forms the main block of cognition cycle. This paper reviews the current trends in research in the domain of spectrum sensing. The author describes the type of channel being modelled, diversity combining schemes used, optimal algorithms applied at fusion centre, spectrum sensing techniques employed. Further, the research challenges are discussed. It is presented that various attributes like sensing time, throughput, rate reliability, optimum cooperative users, sensing frequency etc. needs to be addressed. A trade-off needs to be established to optimize two opposing parameters like sensing and throughput.

  13. Research on Golden-winged Warblers: Recent progress and current needs: Chapter 14

    Science.gov (United States)

    Streby, Henry M.; Rohrbaugh, Roland W.; Buehler, David A.; Andersen, David E.; Vallender, Rachel; King, David I.; Will, Tom

    2016-01-01

    Considerable advances have been made in knowledge about Golden-winged Warblers (Vermivora chrysoptera) in the past decade. Recent employment of molecular analysis, stable-isotope analysis, telemetry-based monitoring of survival and behavior, and spatially explicit modeling techniques have added to, and revised, an already broad base of published knowledge. Here, we synthesize findings primarily from recent peer-reviewed literature on Golden-winged Warblers, from this volume and elsewhere, and we identify some of the substantial remaining research needs. We have organized this synthesis by stages of the Golden-winged Warbler annual cycle. First, we discuss the relatively well-studied breeding-grounds ecology including nesting and post-fledging ecology and hybridization with closely related Blue-winged Warblers (Vermivora cyanoptera). Second, we discuss the much-less-studied, non-breeding-grounds ecology, including the first empirical studies of non-breeding-grounds cover-type associations and spatial and social behavioral ecology. Third, we address migratory connectivity and migration ecology, for which little is known and research has only just begun. Last, we close with cautious optimism that current knowledge is adequate to inform initial conservation and management plans for Golden-winged Warblers, and with a sobering acknowledgement of the quantity of research still needed.

  14. Long-Term Impact of Caregiving and Metabolic Syndrome with Perceived Decline in Cognitive Function 8 Years Later: A Pilot Study Suggesting Important Avenues for Future Research

    OpenAIRE

    Brummett, Beverly H.; Austin, Shirley B.; Welsh-Bohmer, Kathleen A; Williams, Redford B.; Siegler, Ilene C

    2013-01-01

    The chronic stress of caregiving has been associated with increased risk for cognitive decline and dementia. One theoretical model suggests that a group of risk factors known as the metabolic syndrome MET_SYN (e.g. hypertension, poor glucose regulation, central obesity, and high triglyceride levels) that have demonstrated associations with both stress and cognitive decline, may mediate the association between caregiver stress and cognitive decline. It is also possible that caregiving may mode...

  15. Cancer survivorship research: a review of the literature and summary of current NCI-designated cancer center projects.

    Science.gov (United States)

    Harrop, J Phil; Dean, Julie A; Paskett, Electra D

    2011-10-01

    The number of cancer survivors and the amount of cancer survivorship research have grown substantially during the past three decades. This article provides a review of interventional and observational cancer survivorship research efforts as well as a summary of current cancer survivorship research projects being conducted by National Cancer Institute-designated cancer centers in an effort to identify areas that need further attention.

  16. NASA,FAA,ONERA Swept-Wing Icing and Aerodynamics: Summary of Research and Current Status

    Science.gov (United States)

    Broeren, Andy

    2015-01-01

    NASA, FAA, ONERA, and other partner organizations have embarked on a significant, collaborative research effort to address the technical challenges associated with icing on large scale, three-dimensional swept wings. These are extremely complex phenomena important to the design, certification and safe operation of small and large transport aircraft. There is increasing demand to balance trade-offs in aircraft efficiency, cost and noise that tend to compete directly with allowable performance degradations over an increasing range of icing conditions. Computational fluid dynamics codes have reached a level of maturity that they are being proposed by manufacturers for use in certification of aircraft for flight in icing. However, sufficient high-quality data to evaluate their performance on iced swept wings are not currently available in the public domain and significant knowledge gaps remain.

  17. The metabolic syndrome in patients with alcohol dependency: Current research and clinical implications.

    Science.gov (United States)

    Kahl, Kai G; Hillemacher, Thomas

    2016-10-01

    The relationship between alcohol dependency and disorders such as liver disease and cancer has been thoroughly researched. However, the effects of alcohol on cardiometabolic health remain controversial. Several reports found low to moderate alcohol consumption to be associated with a lower risk for cardiometabolic disorders. In contrast, excessive alcohol consumption has been related to an increased risk. Most of these studies were performed in non-clinical populations, therefore limiting the explanatory power to non-dependent patients. Only a few studies examined cardiovascular disorders and cardiovascular risk factors, in particular the metabolic syndrome (MetS), in alcohol dependent patients. We here present a narrative review of studies performed so far on the MetS in alcohol dependency, and provide current hypotheses on the association of alcohol dependency, appetite regulation and the development of the MetS.

  18. Current Status and Recent Research Achievements in SiC/SiC Composites

    Energy Technology Data Exchange (ETDEWEB)

    Katoh, Yutai; Snead, Lance L.; Henager, Charles H.; Nozawa, T.; Hinoki, Tetsuya; Ivekovic, Aljaz; Novak, Sasa; Gonzalez de Vicente, Sehila M.

    2014-12-01

    The development and maturation of the silicon carbide fiber-reinforced silicon carbide matrix (SiC/SiC) composite system for fusion applications has seen the evolution from fundamental development and understanding of the material system and its behavior in a hostile irradiation environment to the current effort which essentially is a broad-based program of technology, directed at moving this material class from a laboratory curiosity to an engineering material. This paper lays out the recent international scientific and technological achievements in the development of SiC/SiC composite material technologies for fusion application and will discuss future research directions. It also reviews the materials system in the larger context of progress to maturity as an engineering material for both the larger nuclear community and for general engineering applications.

  19. Current status and recent research achievements in SiC/SiC composites

    Energy Technology Data Exchange (ETDEWEB)

    Katoh, Y., E-mail: katohy@ornl.gov [Oak Ridge National Laboratory, Oak Ridge, TN (United States); Snead, L.L. [Oak Ridge National Laboratory, Oak Ridge, TN (United States); Henager, C.H. [Pacific Northwest National Laboratory, Richland, WA (United States); Nozawa, T. [Japan Atomic Energy Agency, Rokkasho, Aomori (Japan); Hinoki, T. [Institute of Advanced Energy, Kyoto University, Kyoto (Japan); Iveković, A.; Novak, S. [Jožef Stefan Institute, Ljubljana (Slovenia); Gonzalez de Vicente, S.M. [EFDA Close Support Unit, Garching (Germany)

    2014-12-15

    The silicon carbide fiber-reinforced silicon carbide matrix (SiC/SiC) composite system for fusion applications has seen a continual evolution from development a fundamental understanding of the material system and its behavior in a hostile irradiation environment to the current effort which is directed at a broad-based program of technology maturation program. In essence, over the past few decades this material system has steadily moved from a laboratory curiosity to an engineering material, both for fusion structural applications and other high performance application such as aerospace. This paper outlines the recent international scientific and technological achievements towards the development of SiC/SiC composite material technologies for fusion application and discusses future research directions. It also reviews the materials system in the larger context of progress to maturity as an engineering material for both the larger nuclear community and broader engineering applications.

  20. 绿色建筑的特点研究与发展建议%Characteristic research and development suggestions of green buildings

    Institute of Scientific and Technical Information of China (English)

    李建楠; 赵怀明

    2012-01-01

    The paper introduces contemporary environmental and resource conditions,analyzes characteristics of green buildings,puts forward suggestions of developing green building,and points out the significance of carefully studying conditions of realizing green buildings for achieving sustainable development.%介绍了当前面临的环境和资源的形势,分析了绿色建筑的特点,并提出发展绿色建筑的建议,指出认真研究实现绿色建筑的条件与实践,实现可持续发展,具有重要意义。

  1. Time-dependent ROC curve analysis in medical research: current methods and applications.

    Science.gov (United States)

    Kamarudin, Adina Najwa; Cox, Trevor; Kolamunnage-Dona, Ruwanthi

    2017-04-07

    ROC (receiver operating characteristic) curve analysis is well established for assessing how well a marker is capable of discriminating between individuals who experience disease onset and individuals who do not. The classical (standard) approach of ROC curve analysis considers event (disease) status and marker value for an individual as fixed over time, however in practice, both the disease status and marker value change over time. Individuals who are disease-free earlier may develop the disease later due to longer study follow-up, and also their marker value may change from baseline during follow-up. Thus, an ROC curve as a function of time is more appropriate. However, many researchers still use the standard ROC curve approach to determine the marker capability ignoring the time dependency of the disease status or the marker. We comprehensively review currently proposed methodologies of time-dependent ROC curves which use single or longitudinal marker measurements, aiming to provide clarity in each methodology, identify software tools to carry out such analysis in practice and illustrate several applications of the methodology. We have also extended some methods to incorporate a longitudinal marker and illustrated the methodologies using a sequential dataset from the Mayo Clinic trial in primary biliary cirrhosis (PBC) of the liver. From our methodological review, we have identified 18 estimation methods of time-dependent ROC curve analyses for censored event times and three other methods can only deal with non-censored event times. Despite the considerable numbers of estimation methods, applications of the methodology in clinical studies are still lacking. The value of time-dependent ROC curve methods has been re-established. We have illustrated the methods in practice using currently available software and made some recommendations for future research.

  2. Modeling of the mechano-chemical behaviour of the nuclear pore complex: current research and perspectives.

    Science.gov (United States)

    Garcia, Alberto; Rodriguez Matas, Jose F; Raimondi, Manuela T

    2016-10-10

    Recent evidence suggests that mechanical deformation of the cell nucleus regulates the nuclear import of the transcriptional activators of genes involved in primary physiological cell responses such as stem cell differentiation. In addition, this nuclear mechanosensing response is de-regulated in pathological states, such as cancer and neurodegeneration. One hypothesis that could greatly advance the field is that the deformation of the nuclear envelope activates nuclear pore complexes through a direct mechanical link. The understanding of this possible mechanism for nuclear pore complex stretch-activation entails studying the mechanical connection of this complex to the nuclear envelope at the nanoscale. The nanomechanics of the nuclear pore complex is thus emerging as a novel research field, bridging nanoscience with nanotechnology. This review examines the frontier of research methodologies that are potentially useful for building a computational model of this interaction. This includes, for example, electron tomography to assess the geometrical features of the nuclear pore complex and nanoindentation to estimate its mechanical properties and that of the nuclear envelope. In order to summarize the state-of-the-art and perspectives in the field of NPC nanomechanics, this review covers highly interdisciplinary experimental and theoretical research methodologies pertaining to the fields of physics, chemistry, biology, materials and mechanics.

  3. Reproductive technology and the life course: current debates and research in social egg freezing.

    Science.gov (United States)

    Baldwin, Kylie; Culley, Lorraine; Hudson, Nicky; Mitchell, Helene

    2014-09-01

    While there are currently few confirmed births from previously frozen eggs in the UK, the improved outcomes of new technologies of vitrification and intra-cytoplasmic sperm injection (ICSI) have led to the marketing of egg freezing for non-medical reasons, whereby women are offered the possibility of preserving their eggs until such time as they wish to have a child. Non-academic commentary on this phenomenon has commonly constructed it within a neo-liberal discourse of 'choice', whereby women are positioned as choosing to 'delay motherhood,' often for reasons relating to their careers. However, there have been relatively few research studies which explore either women's awareness and understandings of social egg freezing or the reasons why women consider or undertake egg freezing. This paper summarises the current academic discussion surrounding social egg freezing and outlines the limited body of empirical literature identified from a systematic search of relevant databases. The potential benefits and harms of social egg freezing and the ethical issues it raises are well rehearsed in existing literature, but there is limited empirical evidence about who is accessing social egg freezing, why they are taking this option and what their experiences and future intentions are.

  4. Research of Current Issues and Preliminary Sensitivity Analysis of Level 3 PSA

    Energy Technology Data Exchange (ETDEWEB)

    Shin, So Eun; Lee, Yong Suk [FNC Technology Co. Ltd., Yongin (Korea, Republic of); Lee, Seung Woo [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of)

    2015-10-15

    Thus, in this study, key current issues came from research on previous studies related to L3 PSA. L3 PSA has been carried out by using MACCS code in Korea on a trial basis. The technique of assessing an off-site radiation effect quantitatively is required because the interest in off-site consequence analysis has been increased after the Fukushima accident. Therefore, in order to use Level 3 PSA(L3 PSA) in Korea, methods of calculating MACCS(MELCOR Accident Consequence Code System) code to be adequate for domestic circumstances in Korea were investigated. If L3 PSA is performed in Korea, it will be possible to raise many issues. Since MACCS code is based on the U.S., input parameters and the scope of analysis were set by considering circumstances of the U.S. For this reason, by focusing on solutions to current issues, the method for reflecting circumstances of Korea in L3 PSA was investigated. It is also required to find out methods for decreasing uncertainty of L3 PSA in Korea.

  5. Theories of Suggestion.

    Science.gov (United States)

    Brown, W

    1928-02-01

    The word "suggestion" has been used in educational, scientific and medical literature in slightly different senses. In psychological medicine the use of suggestion has developed out of the earlier use of hypnotic influence.Charcot defined hypnosis as an artificial hysteria, Bernheim as an artificially increased suggestibility. The two definitions need to be combined to give an adequate account of hypnosis. Moreover, due allowance should be made for the factors of dissociation and of rapport in hypnotic phenomena.The relationships between dissociation, suggestibility, and hypnotizability.Theories of suggestion propounded by Pierre Janet, Freud, McDougall, Pawlow and others. Ernest Jones's theory of the nature of auto-suggestion. Janet explains suggestion in terms of ideo-motor action in which the suggested idea, because of the inactivity of competing ideas, produces its maximum effect. Freud explains rapport in terms of the sex instinct "inhibited in its aim" (transference) and brings in his distinction of "ego" and "ego-ideal" (or "super-ego") to supplement the theory. Jones explains auto-suggestion in terms of narcissism. McDougall explains hypnotic suggestion in terms of the instinct of self-abasement. But different instincts may supply the driving power to produce suggestion-effects in different circumstances. Such instincts as those of self-preservation (fear) and gregariousness may play their part. Auto-suggestion as a therapeutic factor is badly named. It supplements, but does not supplant the will, and makes complete volition possible.

  6. The utility of captive animals in actualistic research: A geometric morphometric exploration of the tooth row of Alligator mississippiensis suggesting ecophenotypic influences and functional constraints.

    Science.gov (United States)

    Drumheller, Stephanie K; Wilberg, Eric W; Sadleir, Rudyard W

    2016-07-01

    Captive broad snouted crocodylians are generally thought to have wider, shorter rostra than their wild counterparts. Interpreted to reflect morphological change in response to the conditions of captivity, this qualitative pattern could affect the utility of these animals in a variety of fields of research. However, due to relative ease of access and availability of life history data, captive animals are often utilized in actualistic research. Thus, this issue should be addressed in more detail. Here we explore snout shape variation between captive and wild members of Alligator mississippiensis using two-dimensional (2D) morphometric techniques. Several landmark schemesare used to assess the utility of different aspects of morphology in distinguishing the groups. While statistical analyses consistently differentiated between the groups, the area of morphospace occupied by wild members of A. mississippiensis generally overlapped with the larger area encompassing the captive specimens. This indicates that the captive condition is not as uniform as previously thought and instead encompasses a large spectrum of morphologies, ranging from the stereotypical broad, shortened snouts to outlines that are indistinguishable from the wild morphotype. These results align well with the interpretation that this change reflects an extreme example of ecophenotypy, since ranched, farmed, or zoo organisms are held in an array of enclosures, ranging from indoor, climate controlled pens to outdoor, more natural areas. This variation in environments should be reflected in different reactions to the animals' surroundings, resulting in a broad spectrum of morphotypes. While wild specimens are still preferred, especially for fine scale analyses, these results indicate that not all captive members of A. mississippiensis exhibit the extreme morphological alterations often cited in the literature. Weighing the conditions in which the animals are held and exploring the possibility of

  7. The hydrology of northern peatlands as affected by biogenic gas: Current developments and research needs

    Science.gov (United States)

    Rosenberry, D.O.; Glaser, P.H.; Siegel, D.I.

    2006-01-01

    Recent research indicates that accumulation and release of biogenic gas from northern peatlands may substantially affect future climate. Sudden release of free-phase gas bubbles into the atmosphere may preclude the conversion of methane to carbon dioxide in the uppermost oxic layer of the peat, resulting in greater contribution of methane to the atmosphere than is currently estimated. The hydrology of these peatlands also affects and is affected by this process, especially when gas is released suddenly and episodically. Indirect hydrological evidence indicates that ebullitive gas releases are relatively frequent in some peatlands and time-averaged rates may be significantly greater than diffusive releases. Estimates of free-phase gas contained in peat have ranged from 0 to nearly 20% of the peat volume. Abrupt changes in the volume of gas may alter hydraulic gradients and movement of water and solutes in peat, which in turn could alter composition and fluxes of the gas. Peat surfaces also move vertically and horizontally in response to accumulation and release of free-phase gas. Future research should address the distribution, temporal variability, and relative significance of ebullition in peatlands and the consequent hydrological responses to these gas-emission events. Copyright ?? 2006 John Wiley & Sons, Ltd.

  8. Engaging Girls in STEM: A Discussion of Foundational and Current Research on What Works

    Science.gov (United States)

    Peterson, K.; Jesse, J.; Migus, L. H.

    2012-08-01

    Diversity in science, technology, engineering, and mathematics (STEM) education and careers occupies center stage in national discussions on U.S. competitiveness in the 21st century. Women constitute roughly half the total workforce in the U.S., but they hold just 25% of mathematical and science jobs and 11% of engineering jobs. Women earn nearly 60% of all bachelors and masters degrees, except in physics, computer science, and engineering, where the percentages are 20-25%. This disparity is even more pronounced at the doctoral level, where women earn fewer than 20% of awarded Ph.D.'s in physics or engineering. However, at the high school level, there is far less gender disparity: both female and male students take comparable advanced physical science and math courses. What, then, accounts for the lack of gender diversity in STEM advanced education and career paths? In fact, there is no consensus even among experts. So, what information and strategies do the EPO community need to know and include as part of designing and implementing programs to encourage more girls and women to engage in STEM for the long term? The panelists will discuss foundational and current research on pressing questions on why these trends exist and what can be done to change them. They will highlight research and evaluation results from programs that are successfully engaging girls in STEM.

  9. The current state of the Russian reduced enrichment research reactors program

    Energy Technology Data Exchange (ETDEWEB)

    Aden, V.G.; Kartashov, E.F.; Lukichev, V.A. [and others

    1997-08-01

    During the last year after the 16-th International Conference on Reducing Fuel Enrichment in Research Reactors held in October, 1993 in Oarai, Japan, the conclusive stage of the Program on reducing fuel enrichment (to 20% in U-235) in research reactors was finally made up in Russia. The Program was started late in 70th and the first stage of the Program was completed by 1986 which allowed to reduce fuel enrichment from 80-90% to 36%. The completion of the Program current stage, which is counted for 5-6 years, will exclude the use of the fuel enriched by more than 20% from RF to other countries such as: Poland, Czeck Republick, Hungary, Roumania, Bulgaria, Libya, Viet-Nam, North Korea, Egypt, Latvia, Ukraine, Uzbekistan and Kazakhstan. In 1994 the Program, approved by RF Minatom authorities, has received the status of an inter-branch program since it was admitted by the RF Ministry for Science and Technical Policy. The Head of RF Minatom central administrative division N.I.Ermakov was nominated as the Head of the Russian Program, V.G.Aden, RDIPE Deputy Director, was nominated as the scientific leader. The Program was submitted to the Commission for Scientific, Technical and Economical Cooperation between USA and Russia headed by Vice-President A. Gore and Prime Minister V. Chemomyrdin and was given support also.

  10. Structural dynamics of microsystems—current state of research and future directions

    Science.gov (United States)

    Lin, R. M.; Wang, W. J.

    2006-07-01

    Microsystems or micro-electro-mechanical systems (MEMS), as a newly emerged revolutionary enabling technology, has brought both opportunities and challenges to the field of structural dynamics in a different scale, owing primarily to its interdisciplinary nature of research and extremely small feature size. This paper seeks to present a comprehensive yet critical review on some of the major issues that need to be tackled in the successful realisation of microsystems, with an ultimate objective of further developing and improving the current design capabilities of these systems. The electro-mechanical coupling of typical MEMS devices is first defined and introduced, followed by an in-depth review of the various existing modeling and simulation techniques. Special requirements are discussed when typical MEMS devices need to be tested and existing vibration testing techniques are reviewed. Of particular interest to MEMS devices, structural damping has become a major issue affecting dynamic performance due to the various energy dissipation mechanisms involved. These damping mechanisms have been examined, together with methods developed to model them. Finally, conclusions are made on what have been achieved to date and future prospects of structural dynamics of Microsystems are identified with an intention to stimulate further concerted research in this important emerging area.

  11. Current research, key performances and future development of search and rescue robots

    Institute of Scientific and Technical Information of China (English)

    LIU Jinguo; WANG Yuechao; LI Bin; MA Shugen

    2007-01-01

    Frequent natural disasters and man-made catastrophes have threatened the safety of citizens and have attracted much more attention. The rescue mission under disaster environment is very complicated and dangerous for a rescue team. Search and rescue (SAR) robots can not only improve the efficiency of rescue operations but also reduce the casualty of rescuers. Robots can help rescue teams and even replace rescuers to perform dangerous missions. Search and rescue robots will play a more and more important role in the rescue operations. A survey of the research status of search and rescue robots in Japan, USA, China and other countries has been provided. According to current research,experiences and the lessons learned from applications, the five key performances of a search and rescue robot are survivability, mobility, sensing, communicability and operability.Multi-technique fusion and multi-agent intelligent network are considered to be requirements for the future development of the search and rescue robot. Disaster prevention, disaster reduction and disaster rescue are the important parts of national public safety. They are also crucial for the safety of citizens and their estates. Search and rescue robotic technique is an urgent needed, strategic and core technique for national development. It will be important and strategic for national economy and safety.

  12. [Monogenic obesity - current status of molecular genetic research and clinical importance].

    Science.gov (United States)

    Aldhoon-Hainerová, Irena; Včelák, Josef; Zamrazilová, Hana

    2014-01-01

    Obesity and its comorbidities represent one of the major health problems worldwide. A positive energy balance due to inappropriate life-style changes plays a key role in the current obesity epidemic. The influence of genetic factors is also significant - several studies concluded that genes contribute to the development of obesity by 40-70%. Genetic variability predisposes an individual to tendency or resistance to increase body weight in obesogenic environment. Polygenic type of inheritance is responsible in most of obese individuals. However, an intensive research of the past 20 years has led to an identification of several genes causing monogenic forms of obesity. To date, several monogenic genes (leptin, leptin receptor, prohormon convertase 1, proopiomelanocortin, melanocortin 4 receptor, single-minded homolog 1, brain-derived neurotrophic factor, neurotrophic tyrosine kinase receptor type 2) that are either involved in the neuronal differentiation of the paraventricular nucleus or in the leptin-melanocortin pathway are known to cause obesity. Mutation carriers apart from severe early onset obesity manifest with additional phenotypic characteristics as adrenal insufficiency, impaired immunity and impaired fertility. This review provides an overview of molecular-genetic and clinical research in the field of monogenic obesities including therapeutical approaches.

  13. Current state of particulate matter research and management in Serbia (Introductory paper

    Directory of Open Access Journals (Sweden)

    Milena Jovašević-Stojanović

    2010-09-01

    Full Text Available Particulate matter is the air pollutant that currently receives most attention from the atmospheric research community, the legislative authorities and the general public. Limiting particulate matter in the atmosphere which will result in significant benefits for human health, with associated positive economic consequences. Successful management of particulate matter requires scientific knowledge about particulate matter “from cradle to grave”, covering sources of particles, processes that govern their formation, composition, dispersion and fate in the atmosphere, as well as knowledge about human exposure and associated health and well being. Such knowledge allows to design and perform effective and efficient abatement measures and monitoring. This paper provides an introduction to the research and monitoring regarding particulate matter in Serbia. The contributions were first partly presented at the 2nd international workshop of the WeBIOPATR “Outdoor concentration, size distribution and composition of respirable particles in WB urban area” project in September 2009. This information provides context to the contributions in this number, and was part of the rationale of the project WeBIOPATR.

  14. [Patient-centredness in rehabilitation : an overview on the current state of research].

    Science.gov (United States)

    Farin, E

    2014-02-01

    This article provides an overall perspective of the concept of patient-centredness in health care. After discussing the social factors that significantly contribute to this topic, the authors refer to a definition by Mead and Bower in their understanding of patient-centredness. They distinguished five facets of patient-centredness, namely the biopsychosocial perspective, seeing the patient as an individual person, sharing power and responsibility (e.g. shared decision-making), consideration of the patient-treatment provider relationship and regarding the treatment provider as a person. The authors discuss why approaches employing patient-centred care seem particularly well-suited to a rehabilitation context and emphasize the value and benefit of patient-centred care. They describe those areas currently engaging the greatest research efforts in Germany by providing an overview of projects now being conducted in the funding priority for chronic illnesses and patient orientation. In the final chapter the authors consider the need for further research as well as the potential adverse side effects associated with intensified patient-centred care.

  15. Research on the Current Telecommuting Trends in United States and European Union Markets

    Directory of Open Access Journals (Sweden)

    Catalina Georgiana PICU

    2016-12-01

    Full Text Available In the context of globalization and due to the accelerated progress made in information and communication technology, more and more companies offer their employees the option of telecommuting. For the past twenty years, telecommuting has been on an asceding trend, an incresing number of people embracing the ability to work from home, using a computer and internet connection to communicate for their jobs. The goal of the paper is to explain the overall notion of telecommuting and to analyze the current trends in the United States and European Union markets. Another objective is to assess the advantages and disadvantages of telecommuting and the important role played by this concept within the striving purpose of corporations to achieve their strategic targets. The study is based upon specialized literature reviews regarding the emergence of telecommuting and the role it plays in organizations. A comparative analysis was conducted by the authors on two regional markets, United States and the European Union, in order to assess the trend in telecommuting and the factors that influence it. The outcome of the research shows that although the benefits of telecommuting are numerous, it does not come without challenges, both being applicable for both the employer, as well as for the employee. The research results of this study can be used by organizations when considering to offer their employees flexible work opportunities which can positively influence the long term business performance.

  16. European seismological data exchange, access and processing: current status of the Research Infrastructure project NERIES

    Science.gov (United States)

    Giardini, D.; van Eck, T.; Bossu, R.; Wiemer, S.

    2009-04-01

    The EC Research infrastructure project NERIES, an Integrated Infrastructure Initiative in seismology for 2006-2010 has passed its mid-term point. We will present a short concise overview of the current state of the project, established cooperation with other European and global projects and the planning for the last year of the project. Earthquake data archiving and access within Europe has dramatically improved during the last two years. This concerns earthquake parameters, digital broadband and acceleration waveforms and historical data. The Virtual European Broadband Seismic Network (VEBSN) consists currently of more then 300 stations. A new distributed data archive concept, the European Integrated Waveform Data Archive (EIDA), has been implemented in Europe connecting the larger European seismological waveform data. Global standards for earthquake parameter data (QuakeML) and tomography models have been developed and are being established. Web application technology has been and is being developed to make a jump start to the next generation data services. A NERIES data portal provides a number of services testing the potential capacities of new open-source web technologies. Data application tools like shakemaps, lossmaps, site response estimation and tools for data processing and visualisation are currently available, although some of these tools are still in an alpha version. A European tomography reference model will be discussed at a special workshop in June 2009. Shakemaps, coherent with the NEIC application, are implemented in, among others, Turkey, Italy, Romania, Switzerland, several countries. The comprehensive site response software is being distributed and used both inside and outside the project. NERIES organises several workshops inviting both consortium and non-consortium participants and covering a wide range of subjects: ‘Seismological observatory operation tools', ‘Tomography', ‘Ocean bottom observatories', 'Site response software training

  17. Current research issues related to post-wildfire runoff and erosion processes

    Science.gov (United States)

    Moody, John A.; Shakesby, Richard A.; Robichaud, Peter R.; Cannon, Susan H.; Martin, Deborah A.

    2013-01-01

    Research into post-wildfire effects began in the United States more than 70 years ago and only later extended to other parts of the world. Post-wildfire responses are typically transient, episodic, variable in space and time, dependent on thresholds, and involve multiple processes measured by different methods. These characteristics tend to hinder research progress, but the large empirical knowledge base amassed in different regions of the world suggests that it should now be possible to synthesize the data and make a substantial improvement in the understanding of post-wildfire runoff and erosion response. Thus, it is important to identify and prioritize the research issues related to post-wildfire runoff and erosion. Priority research issues are the need to: (1) organize and synthesize similarities and differences in post-wildfire responses between different fire-prone regions of the world in order to determine common patterns and generalities that can explain cause and effect relations; (2) identify and quantify functional relations between metrics of fire effects and soil hydraulic properties that will better represent the dynamic and transient conditions after a wildfire; (3) determine the interaction between burned landscapes and temporally and spatially variable meso-scale precipitation, which is often the primary driver of post-wildfire runoff and erosion responses; (4) determine functional relations between precipitation, basin morphology, runoff connectivity, contributing area, surface roughness, depression storage, and soil characteristics required to predict the timing, magnitudes, and duration of floods and debris flows from ungaged burned basins; and (5) develop standard measurement methods that will ensure the collection of uniform and comparable runoff and erosion data. Resolution of these issues will help to improve conceptual and computer models of post-wildfire runoff and erosion processes.

  18. Study on workloads of human care worker with the introduction of IT system - the characteristics of work loads by observational research and the suggestions for KAIZEN.

    Science.gov (United States)

    Mizuno, Yuki; Yoshikawa, Toru; Matsuda, Fumiko; Takeuchi, Yuriko; Motegi, Nobuyuki; Ikegami, Thor; Sakai, Kazuhiro

    2012-01-01

    The purpose of this study was to clarify the characteristic of workloads on human care worker with the introduction of IT system, and suggested the support measures for KAIZEN in Japan. The investigation method is workflow line and hearing with a focus on work observation. The objects were 8 human care workers of the acute hospital that introduced an electronic system. By the introduction of the electronic chart, the nurse station sojourn time decreased, sickroom sojourn time increased, and time about direct nursing care to a patient increased. In addition, access to patient information became easy, and the offer of the health care service based on correct information came to be possible in real time. By The point of workflow line, it was effect that moving lengths decreased in order to install the electronic chart in patients' rooms. Though, it was a problem that it hasn't formed where to place the instruments such as sphygmomanometer, clinical thermometer and others.

  19. Research on the Structure Paradigm for Government Online Suggestions & Proposals%基层政务网上建议提案结构范式研究

    Institute of Scientific and Technical Information of China (English)

    王孝琪; 赵丽维; 黄媛

    2013-01-01

    政协委员提案和人大代表建议经审查立案后,政府能否有效、低成本办理并及时答复提(议)案者,直接体现人民政府效能。在当今信息技术条件下,借鉴国内外提(议)案在线系统开发经验,构建基层政务网上提(议)案结构范式,对建立高效、节约、法治、廉洁、服务型政府以及实现对社会的创新管理,具有重要的现实意义。%After examining the proposals of members of the CPPCC and suggestions of deputy to National People’s Congress and putting them on record, the government can handle them effectively and answer their proposers timely at low cost, reflects directly the efficiency of the people’s government. In the conditions of modern information technology, learning from the developing experiences of online proposals system from both at home and abroad, and building the structure paradigm for proposals and suggestions on the net of government affairs at basic level have great practical significance to building an effective, economical, law-based, clean-fingered and service-oriented government and realizing the innovation management of the society.

  20. 基于SWOT模型的四川创新团队发展现状分析及建议%Analysis on Current Status of Innovation Team Development in Sichuan Province Based on SWOT Model and Suggestions

    Institute of Scientific and Technical Information of China (English)

    景晓卫; 李晓; 雷波

    2015-01-01

    加强四川创新团队建设是提升科技支撑产业发展、促进农业产业提档升级的有效方式.文章采用SWOT模型分析了四川创新团队在科研力量、优势产业和管理方式等方面的优势,以及在科技协作、经费投入等方面的劣势.提出了通过加强组织领导和管理创新、突出成果转化应用和大力培育新型职业农民等促进四川创新团队健康、持续发展的建议.%Strengthening the construction of innovation team is the effective way of promoting the development of scientific supporting industry and accelerating the upgrade of agricultural industry. In this article, innovation team of Sichuan Province was analyzed by SWOT model, which has advantages in scientific research force, superior industry and management mode, and has main obstacles in cooperative mode and fund input. Suggestions to promote healthy and sustainable development of innovation team in Sichuan Province were put forward, i.e., strengthening the organization leadership and management innovation, laying stress on transformation and application of achievements, and cultivating new type of professional farmers.