WorldWideScience

Sample records for current research focus

  1. A European Perspective on Auditory Processing Disorder-Current Knowledge and Future Research Focus

    Directory of Open Access Journals (Sweden)

    Vasiliki (Vivian Iliadou

    2017-11-01

    Full Text Available Current notions of “hearing impairment,” as reflected in clinical audiological practice, do not acknowledge the needs of individuals who have normal hearing pure tone sensitivity but who experience auditory processing difficulties in everyday life that are indexed by reduced performance in other more sophisticated audiometric tests such as speech audiometry in noise or complex non-speech sound perception. This disorder, defined as “Auditory Processing Disorder” (APD or “Central Auditory Processing Disorder” is classified in the current tenth version of the International Classification of diseases as H93.25 and in the forthcoming beta eleventh version. APDs may have detrimental effects on the affected individual, with low esteem, anxiety, and depression, and symptoms may remain into adulthood. These disorders may interfere with learning per se and with communication, social, emotional, and academic-work aspects of life. The objective of the present paper is to define a baseline European APD consensus formulated by experienced clinicians and researchers in this specific field of human auditory science. A secondary aim is to identify issues that future research needs to address in order to further clarify the nature of APD and thus assist in optimum diagnosis and evidence-based management. This European consensus presents the main symptoms, conditions, and specific medical history elements that should lead to auditory processing evaluation. Consensus on definition of the disorder, optimum diagnostic pathway, and appropriate management are highlighted alongside a perspective on future research focus.

  2. The Focus of Current HCI Research in Usability Evaluation and Feedback

    DEFF Research Database (Denmark)

    Høegh, Rune Thaarup

    2007-01-01

    This paper presents the findings from a systematic literature study of the research on usability evaluation and feedback. The literature study covers the papers published from five key human-computer interaction journals for a period of four years, and depicts the most current research within...... the field with regard to usability evaluation and feedback....

  3. A European Perspective on Auditory Processing Disorder-Current Knowledge and Future Research Focus

    DEFF Research Database (Denmark)

    IIiadou, Vasiliki; Ptok, Martin; Grech, Helen

    2017-01-01

    Current notions of "hearing impairment," as reflected in clinical audiological practice, do not acknowledge the needs of individuals who have normal hearing pure tone sensitivity but who experience auditory processing difficulties in everyday life that are indexed by reduced performance in other...... of diseases as H93.25 and in the forthcoming beta eleventh version. APDs may have detrimental effects on the affected individual, with low esteem, anxiety, and depression, and symptoms may remain into adulthood. These disorders may interfere with learning per se and with communication, social, emotional......, and academic-work aspects of life. The objective of the present paper is to define a baseline European APD consensus formulated by experienced clinicians and researchers in this specific field of human auditory science. A secondary aim is to identify issues that future research needs to address in order...

  4. How do scientists perceive the current publication culture? A qualitative focus group interview study among Dutch biomedical researchers.

    Science.gov (United States)

    Tijdink, J K; Schipper, K; Bouter, L M; Maclaine Pont, P; de Jonge, J; Smulders, Y M

    2016-02-17

    To investigate the biomedical scientist's perception of the prevailing publication culture. Qualitative focus group interview study. Four university medical centres in the Netherlands. Three randomly selected groups of biomedical scientists (PhD, postdoctoral staff members and full professors). Main themes for discussion were selected by participants. Frequently perceived detrimental effects of contemporary publication culture were the strong focus on citation measures (like the Journal Impact Factor and the H-index), gift and ghost authorships and the order of authors, the peer review process, competition, the funding system and publication bias. These themes were generally associated with detrimental and undesirable effects on publication practices and on the validity of reported results. Furthermore, senior scientists tended to display a more cynical perception of the publication culture than their junior colleagues. However, even among the PhD students and the postdoctoral fellows, the sentiment was quite negative. Positive perceptions of specific features of contemporary scientific and publication culture were rare. Our findings suggest that the current publication culture leads to negative sentiments, counterproductive stress levels and, most importantly, to questionable research practices among junior and senior biomedical scientists. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  5. Doing focus group research

    DEFF Research Database (Denmark)

    Lindegaard, Laura Bang

    2014-01-01

    Scholars of ethnomethodologically informed discourse studies are often sceptical of the use of interview data such as focus group data. Some scholars quite simply reject interview data with reference to a general preference for so-called naturally occurring data. Other scholars acknowledge...... that interview data can be of some use if the distinction between natural and contrived data is given up and replaced with a distinction between interview data as topic or as resource. In greater detail, such scholars argue that interview data are perfectly adequate if the researcher wants to study the topic...... of interview interaction, but inadequate as data for studying phenomena that go beyond the phenomenon of interview interaction. Neither of these more and less sceptical positions are, on the face of it, surprising due to the ethnomethodological commitment to study social order as accomplished in situ...

  6. Current Research Studies

    Science.gov (United States)

    ... Success Home > Explore Research > Current Research Studies Current Research Studies Email Print + Share The Crohn’s & Colitis Foundation ... conducted online. Learn more about IBD Partners. Clinical Research Alliance The Clinical Research Alliance is a network ...

  7. Research on anisotropy of fusion-produced protons and neutrons emission from high-current plasma-focus discharges

    Energy Technology Data Exchange (ETDEWEB)

    Malinowski, K., E-mail: karol.malinowski@ncbj.gov.pl; Sadowski, M. J.; Szydlowski, A. [National Centre for Nuclear Research (NCBJ), 05-400 Otwock (Poland); Institute of Plasma Physics and Laser Microfusion (IFPiLM), 01-497 Warsaw (Poland); Skladnik-Sadowska, E.; Czaus, K.; Kwiatkowski, R.; Zaloga, D. [National Centre for Nuclear Research (NCBJ), 05-400 Otwock (Poland); Paduch, M.; Zielinska, E. [Institute of Plasma Physics and Laser Microfusion (IFPiLM), 01-497 Warsaw (Poland)

    2015-01-15

    The paper concerns fast protons and neutrons from D-D fusion reactions in a Plasma-Focus-1000U facility. Measurements were performed with nuclear-track detectors arranged in “sandwiches” of an Al-foil and two PM-355 detectors separated by a polyethylene-plate. The Al-foil eliminated all primary deuterons, but was penetrable for fast fusion protons. The foil and first PM-355 detector were penetrable for fast neutrons, which were converted into recoil-protons in the polyethylene and recorded in the second PM-355 detector. The “sandwiches” were irradiated by discharges of comparable neutron-yields. Analyses of etched tracks and computer simulations of the fusion-products behavior in the detectors were performed.

  8. Reducing Current Spread using Current Focusing in Cochlear Implant Users

    Science.gov (United States)

    Landsberger, David M.; Padilla, Monica; Srinivasan, Arthi G.

    2012-01-01

    Cochlear implant performance in difficult listening situations is limited by channel interactions. It is known that partial tripolar (PTP) stimulation reduces the spread of excitation (SOE). However, the greater the degree of current focusing, the greater the absolute current required to maintain a fixed loudness. As current increases, so does SOE. In experiment 1, the SOE for equally loud stimuli with different degrees of current focusing is measured via a forward-masking procedure. Results suggest that at a fixed loudness, some but not all patients have a reduced SOE with PTP stimulation. Therefore, it seems likely that a PTP speech processing strategy could improve spectral resolution for only those patients with a reduced SOE. In experiment 2, the ability to discriminate different levels of current focusing was measured. In experiment 3, patients subjectively scaled verbal descriptors of stimuli of various levels of current focusing. Both discrimination and scaling of verbal descriptors correlated well with SOE reduction, suggesting that either technique have the potential to be used clinically to quickly predict which patients would receive benefit from a current focusing strategy. PMID:22230370

  9. Current scaling of plasma focus devices

    International Nuclear Information System (INIS)

    Schiuma, C.; Herold, H.; Kaeppeler, H.J.; Shakhatre, M.; Auluck, S.K.H.

    1990-03-01

    In continuation of the work by G. Decker et al. on current and neutron yield scaling of plasma focus devices an analytical solution for the circuit equation (with resistance R = 0) in the compression phase was derived. Together with the solution for the rundown phase from G. Decker et al, which was extended for finite resistance (R ≠ 0), there follows an analytical scaling theory for maximum and pinch currents. At the same time there exists the possibility to discuss the influence of finite resistance on current variation and scaling parameters. The model solutions were checked out by numerical integrations of the current equation. While at the beginning of the rundown phase the ohmic resistance cannot be neglected (the magnitude R/L plays an important role), its influence at the end of the rundown phase and in the compression phase is negligible. The theoretically determined values are compared with the results of numerous probe measurements. (orig.)

  10. Focus groups in organizational research

    Directory of Open Access Journals (Sweden)

    L. Kamfer

    1989-05-01

    Full Text Available Focus groups are commonly used in marketing research. In this article an application of the focus group technique within an organizational context is described. Nine focus groups were conducted during the planning stage of a survey intended to establish employee perceptions of advancement policies and practices in a major South African manufacturing company. Fourteen themes emerged from a content analysis of the discussions. Two of these reflected aspects requiring commitment decisions from management toward the survey. The others indicated areas of concern which should be included in the survey. In this way, the focus groups contributed useful information for the subsequent sample survey. Opsomming Fokusgroepe word algemeen in bemarkingsnavorsing aangewend. In hierdie studie word 'n toepassingvan die fokusgroeptegniek in die konteks van 'n opname binne 'n organisasie beskryf. Nege fokusgroepbesprekings is gevoer tydens die beplanningstadium van 'n opname wat binne 'n Suid-Afrikaanse vervaardigingsonderneming gedoen is. Die doel van die opname was om die persepsies van werknemers teenoor die bestaande personeel- en bestuursontwikkelingsbeleid en -praktyke van die maatskappy te bepaal. Veertien temas is deur middel van 'n inhoudontleding gei'dentifiseer. Twee hiervan het aspekte aangedui waaroor bestuur beginselbesluite t.o.v. die opname sou moes neem. Die ander het probleemareas aangedui wat by die ondersoek selfingesluit behoort te word. Sodoende het die fokusgroepe inligting verskafwat vir die latere vraelysopname belangrik was.

  11. Social networks user: current research

    OpenAIRE

    Agadullina E.R.

    2015-01-01

    The purpose of this article is to review current research studies focusing on the users of Facebook and their behaviors in social networks. This review is organized into two sections: 1) social-demographic characteristics (Age, Gender, Nationality); 2) personality characteristics (Neuroticism, Extraversion, Openness-to-Experience, Agreeableness, Conscientiousness, Narcissism, Self-esteem). The results showed that the information in the personal profile and online behavior are strongly connect...

  12. Social networks user: current research

    Directory of Open Access Journals (Sweden)

    Agadullina E.R.

    2015-12-01

    Full Text Available The purpose of this article is to review current research studies focusing on the users of Facebook and their behaviors in social networks. This review is organized into two sections: 1 social-demographic characteristics (Age, Gender, Nationality; 2 personality characteristics (Neuroticism, Extraversion, Openness-to-Experience, Agreeableness, Conscientiousness, Narcissism, Self-esteem. The results showed that the information in the personal profile and online behavior are strongly connected with socio-demographic and personality characteristics

  13. Focus on nuclear fusion research

    Czech Academy of Sciences Publication Activity Database

    Křenek, Petr; Mlynář, Jan

    2011-01-01

    Roč. 61, - (2011), s. 62-63 ISSN 0375-8842 Institutional research plan: CEZ:AV0Z20430508 Keywords : ITER * COMPASS * fusion energy * tokamak * EURATOM Subject RIV: BL - Plasma and Gas Discharge Physics http://www.ipp.cas.cz/Tokamak/clanky/energetika_COMPASS.pdf

  14. The Current Status of STEM Education Research

    Science.gov (United States)

    Brown, Josh

    2012-01-01

    This paper explores the current Science, Technology, Engineering and Mathematics (STEM) education research base through an analysis of articles from eight journals focused on the STEM disciplines. Analyzed are both practitioner and research publications to determine the current scope of STEM education research, where current STEM education…

  15. Current Solid Mechanics Research

    DEFF Research Database (Denmark)

    Tvergaard, Viggo

    2016-01-01

    About thirty years ago James Lighthill wrote an essay on “What is Mechanics?” With that he also included some examples of the applications of mechanics. While his emphasis was on fluid mechanics, his own research area, he also included examples from research activities in solid mechanics....

  16. Current cancer research 1998

    Energy Technology Data Exchange (ETDEWEB)

    Stamatiadis-Smidt, H. [ed.

    1998-12-31

    Topics from the Contents: The Fight against Cancer in Germany - A Critical Review. Conditions and Structures in Research. Familial Breast Cancer - A Critical Assessment. Research without Animal Experiments. Cancer Prevention. New Approaches for Tumor Therapy. Genes, Chromosomes and Cancer. Therapy of Brain Tumors with Laser Neurosurgery. The Genome Project. (orig.)

  17. Current cancer research 1998

    International Nuclear Information System (INIS)

    Stamatiadis-Smidt, H.

    1998-01-01

    Topics from the Contents: The Fight against Cancer in Germany - A Critical Review. Conditions and Structures in Research. Familial Breast Cancer - A Critical Assessment. Research without Animal Experiments. Cancer Prevention. New Approaches for Tumor Therapy. Genes, Chromosomes and Cancer. Therapy of Brain Tumors with Laser Neurosurgery. The Genome Project. (orig.)

  18. Using Focus Group Research in Public Relations.

    Science.gov (United States)

    Grunig, Larissa A.

    1990-01-01

    Analyzes a recent instance of focus group research applied to a public relations case (rather than a marketing case). Reviews the advantages and disadvantages of this qualitative method, and describes the case of a county department of mental health relying on focus group research to help plan a program aimed at reducing the stigma of mental…

  19. Current clinical research environment: focus on psychiatry Cenário atual da pesquisa clínica: foco em psiquiatria

    Directory of Open Access Journals (Sweden)

    Sonia Mansoldo Dainesi

    2007-09-01

    Full Text Available The introduction of international guidelines on Good Clinical Practices (GCP in 1996, immediately followed by the publication of Resolution CNS 196/96 in Brazil, created a great opportunity for Brazilian research centers to participate in international trials. Such studies must be strictly monitored in order to assure compliance with the regulations, as well as with the standards of patient safety. Clear agreement among the investigator, the sponsor and the institution carrying out the study must be previously defined in order to avoid any conflicts of interest during or after the study. Operational aspects, such as the time needed to gain regulatory approval of the study design, strategies for patient recruitment/retention and appropriate logistics, are also important. In 2005, the Brazilian National Clinical Research Network was established, bringing together a number of research centers in teaching hospitals. The objective was to subsidize public clinical research with state-of-the-art practices and appropriate technical/scientific training programs. The development of research protocols that prioritize public health care needs in Brazil is other fundamental goal of this network. This article addresses general aspects of clinical research, as well as some specific issues in psychiatry. Improving the health and quality of life of the global population is certainly the major objective of all of the work done in this area.A introdução de diretrizes internacionais de Boas Práticas Clínicas, em 1996, imediatamente seguida pela publicação da Resolução do Conselho Nacional de Saúde 196/96, abriu uma grande oportunidade para a participação de centros de pesquisa brasileiros em estudos internacionais. Tais estudos devem ser estritamente monitorados, a fim de assegurar a adesão às legislações, assim como garantir a segurança dos pacientes envolvidos. A fim de evitar possíveis conflitos de interesse durante e após o estudo, todos os

  20. Focus on Basics: Connecting Research & Practice. Volume 7, Issue D

    Science.gov (United States)

    Garner, Barbara, Ed.

    2005-01-01

    "Focus on Basics" is the quarterly publication of the National Center for the Study of Adult Learning and Literacy. It presents best practices, current research on adult learning and literacy, and how research is used by adult basic education teachers, counselors, program administrators, and policymakers. "Focus on Basics" is…

  1. Virtual Focus Groups: New Frontiers in Research

    Directory of Open Access Journals (Sweden)

    Lyn Turney

    2005-06-01

    Full Text Available New information and communication technologies in the form of learning management systems provide unique and inventive opportunities for qualitative researchers. Their intrinsic ability to record discursive data in text format accurately and to provide safe, secure, and anonymous environments for participants makes them amenable for use as advanced research tools. In this article, the authors report on a collaborative project that tested the potential of online discussion boards for use in virtual focus groups. What the researchers found was that not only was the method theoretically sound, it actually enhanced their ability to connect with difficult-to-access populations that were disparately spread.

  2. BIOENERGIA - Focus on wood in bioenergy research

    Energy Technology Data Exchange (ETDEWEB)

    Asplund, D. [Jyvaeskylae Science Park, Jyvaeskylae (Finland)

    1996-12-31

    The most important area of research on wood fuel production is the development of various methods, machines and systems connected to this area, in order to produce economically competitive fuels. The integrated harvesting methods, which supply both raw material to wood products industry and wood fuel for energy production, have been chosen the main research area because they seem to be most promising. The growing amount of small-sized trees ant the need of their first thinnings have created a demand for new harvesting methods. At the moment the economical aspects restrict the harvesting of the first thinning trees either for industrial use or energy production. Research on peat production focuses on the complete use of a bog and on the development of peat production methods and machines. Development work in this area aims at decreasing production costs and also at reducing the drainage water and other elements in environmental load around the peat production sites. The use of bioenergy research will be focused on the small-scale (<20 MW{sub th},) applications. In the long term, the increase of bioenergy in heating of small houses and farms and buildings, as well as in the production of heat and power has been estimated. Research into the conversion of biomass is concentrated on the production of biomass-based liquid fuels

  3. [Focused ultrasound therapy: current status and potential applications in neurosurgery].

    Science.gov (United States)

    Dervishi, E; Aubry, J-F; Delattre, J-Y; Boch, A-L

    2013-12-01

    High Intensity Focused Ultrasound (HIFU) therapy is an innovative approach for tissue ablation, based on high intensity focused ultrasound beams. At the focus, HIFU induces a temperature elevation and the tissue can be thermally destroyed. In fact, this approach has been tested in a number of clinical studies for the treatment of several tumors, primarily the prostate, uterine, breast, bone, liver, kidney and pancreas. For transcranial brain therapy, the skull bone is a major limitation, however, new adaptive techniques of phase correction for focusing ultrasound through the skull have recently been implemented by research systems, paving the way for HIFU therapy to become an interesting alternative to brain surgery and radiotherapy. Copyright © 2013 Elsevier Masson SAS. All rights reserved.

  4. Remote sub-wavelength focusing of ultrasonically activated Lorentz current

    Science.gov (United States)

    Rekhi, Angad S.; Arbabian, Amin

    2017-04-01

    We propose the use of a combination of ultrasonic and magnetic fields in conductive media for the creation of RF electrical current via the Lorentz force, in order to achieve current generation with extreme sub-wavelength resolution at large depth. We demonstrate the modeling, generation, and measurement of Lorentz current in a conductive solution and show that this current can be localized at a distance of 13 cm from the ultrasonic source to a region about three orders of magnitude smaller than the corresponding wavelength of electromagnetic waves at the same operation frequency. Our results exhibit greater depth, tighter localization, and closer agreement with prediction than previous work on the measurement of Lorentz current in a solution of homogeneous conductivity. The proposed method of RF current excitation overcomes the trade-off between focusing and propagation that is fundamental in the use of RF electromagnetic excitation alone and has the potential to improve localization and depth of operation for RF current-based biomedical applications.

  5. Topics in current aerosol research

    CERN Document Server

    Hidy, G M

    1971-01-01

    Topics in Current Aerosol Research deals with the fundamental aspects of aerosol science, with emphasis on experiment and theory describing highly dispersed aerosols (HDAs) as well as the dynamics of charged suspensions. Topics covered range from the basic properties of HDAs to their formation and methods of generation; sources of electric charges; interactions between fluid and aerosol particles; and one-dimensional motion of charged cloud of particles. This volume is comprised of 13 chapters and begins with an introduction to the basic properties of HDAs, followed by a discussion on the form

  6. Rotating flux-focusing eddy current probe for flaw detection

    Science.gov (United States)

    Wincheski, Russell A. (Inventor); Fulton, James P. (Inventor); Nath, Shridhar C. (Inventor); Simpson, John W. (Inventor); Namkung, Min (Inventor)

    1997-01-01

    A flux-focusing electromagnetic sensor which uses a ferromagnetic flux-focusing lens simplifies inspections and increases detectability of fatigue cracks about circular fasteners and other circular inhomogeneities in high conductivity material. The unique feature of the device is the ferrous shield isolating a high-turn pick-up coil from an excitation coil, The use of the magnetic shield is shown to produce a null voltage output across the receiving coil in the presence of an unflawed sample. A redistribution of the current flow in the sample caused by the presence of flaws, however, eliminates the shielding condition and a large output voltage is produced, yielding a clear unambiguous flaw signal. By rotating the probe in a path around a circular fastener such as a rivet while maintaining a constant distance between the probe and the center of a rivet, the signal due to current flow about the rivet can be held constant. Any further changes in the current distribution, such as due to a fatigue crack at the rivet joint, can be detected as an increase in the output voltage above that due to the flow about the rivet head.

  7. Ion clusters, REB, and current sheath characteristics in focused discharges

    International Nuclear Information System (INIS)

    Bortolotti, A.; Brzosko, J.; DeChiara, P.; Kilic, H.; Mezzetti, F.; Nardi, V.; Powell, C.; Zeng, D.

    1990-01-01

    Small fluctuations in the current sheath characteristics (peak current density, FWHM of leading sheath, control parameters of sheath internal structure) are linked to wide fluctuations of ion and ion cluster emission from the pinch. Magnetic probe data are used for correlating variations of current sheath parameters with particle emission intensity, Z/M composition, particle energy spectrum. The emission of ion and ion clusters at 90 degrees from the axis of a plasma focus discharge is monitored simultaneously with the 0 degrees emission. The particle energy spectrum is analyzed with a Thomson (parabola) spectrometer (time resolution ∼ 1 nanosec). The cross-sectional structure of the REB at 180 degrees along the discharge axis is monitored via the deposition of collective-field accelerated ions on a target in the REB direction. Etched tracks of ion and ion clusters are in all cases recorded on CR-39 plates. Sharp peaks of the D + -ion spectrum at 90 degrees are found for E > 200 keV/unit charge in all focused discharges. These peaks are due to ion crossing of the azimuthal magnetic field of the pinch region, in a predominant ion cluster structure

  8. Reengineering Clinical Research Science: A Focus on Translational Research

    Science.gov (United States)

    Ferrell, Courtney B.

    2009-01-01

    The burden of disease in the United States is high. Mental illness is currently the leading cause of disease burden among 15- to 44-year-olds. This phenomenon is occurring despite the many advances that have been made in clinical research. Several efficacious interventions are available to treat many of these disorders; however, they are greatly…

  9. Oscillation of the current sheet velocity in plasma focus discharges

    International Nuclear Information System (INIS)

    Melzacki, K.; Nardi, V.

    1994-01-01

    The oscillation of the propagation speed of the plasma focus current sheet has been recorded with schlieren photography. The sheet stuttering in the propagation during the implosion phase has a frequency of about 60 MHz. The effect could be recorded due to application of long exposure time (60 ns) technique. It is not detectable in the subnanosecond pictures. The pictures are taken in black schlieren. The probing range of the electron density gradient, with integration along the path of the 1 J, Q-switched ruby laser beam, has been selected by the size of the stop and aperture within 3 x 10 18 cm -3 and 3 x 10 20 cm -3 . Raising the sensitivity threshold to 2 x 10 19 cm -3 (refraction angle of 4 mrad) has helped to clear the pictures by limiting their image to high gradients of density only. With this technique (and other diagnostic methods) the dynamics of 6 kJ, 16 kV plasma focus discharges in deuterium at 5 torr, with a 10% decrease of the magnetic insulation at the breech has been investigated. The average implosion velocity of the current sheath obtained with this effect, 5 x 10 6 cm/s, is consistent with those measured by the smear effect, and the electric probe. The electron density gradient has been determined at several instants; at the pinch time it is (3 ± 1.5) x 10 20 cm -4 . The data are discussed on the basis of several pictures

  10. Current directions in radiopharmaceutical research

    Energy Technology Data Exchange (ETDEWEB)

    Mather, S J [Department of Nuclear Medicine, St. Bartholomew` s Hospital, London (United Kingdom)

    1998-08-01

    Much of current radiopharmaceutical research is directed towards the development of receptor-binding tracers which are targeted towards biochemical processes. These may be extra or intracellular in nature and hold promise for an imaging approach to tissue characterisation in-vivo. Many of these products are based on proteins which range in size from large monoclonal antibodies to small neuropeptides and share a radiolabelling chemistry based on the use of bifunctional chelating agents. Although developed initially for use with indium-111, considerations of cost and isotope availability have continued to direct the efforts of many researchers towards the use of technetium-99m. While polypeptide-based radiopharmaceuticals may be useful for imaging peripheral cell-surface receptors, access to sites of interest within the cell, or in the brain, requires the development of small lipophilic molecules with retained ability to interact with intracellular targets. The design and synthesis of these compounds presents a particular challenge to the radiopharmaceutical chemist which is being met through either a pendant or integrated approach to the use of technetium coordination with particular emphasis on technetium (v) cores. Progress continues to be made in the application of targeted radionuclide therapy particularly in the development of radiopharmaceuticals for the treatment of malignant bone disease. methods for labelling antibodies with a great variety of cytotoxic radionuclides have now been refined and their use for radioimmunotherapy in the treatment of haematological malignancies shows great promise. The major medical areas for application of these new radiopharmaceuticals will be in oncology, neurology and inflammation but the increasingly difficult regulatory climate in which drug development and health-care now operate will make it essential for researchers to direct their products toward specific clinical problems as well as biological targets. (author) 36 refs

  11. Current directions in radiopharmaceutical research

    International Nuclear Information System (INIS)

    Mather, S.J.

    1998-01-01

    Much of current radiopharmaceutical research is directed towards the development of receptor-binding tracers which are targeted towards biochemical processes. These may be extra or intracellular in nature and hold promise for an imaging approach to tissue characterisation in-vivo. Many of these products are based on proteins which range in size from large monoclonal antibodies to small neuropeptides and share a radiolabelling chemistry based on the use of bifunctional chelating agents. Although developed initially for use with indium-111, considerations of cost and isotope availability have continued to direct the efforts of many researchers towards the use of technetium-99m. While polypeptide-based radiopharmaceuticals may be useful for imaging peripheral cell-surface receptors, access to sites of interest within the cell, or in the brain, requires the development of small lipophilic molecules with retained ability to interact with intracellular targets. The design and synthesis of these compounds presents a particular challenge to the radiopharmaceutical chemist which is being met through either a pendant or integrated approach to the use of technetium coordination with particular emphasis on technetium (v) cores. Progress continues to be made in the application of targeted radionuclide therapy particularly in the development of radiopharmaceuticals for the treatment of malignant bone disease. methods for labelling antibodies with a great variety of cytotoxic radionuclides have now been refined and their use for radioimmunotherapy in the treatment of haematological malignancies shows great promise. The major medical areas for application of these new radiopharmaceuticals will be in oncology, neurology and inflammation but the increasingly difficult regulatory climate in which drug development and health-care now operate will make it essential for researchers to direct their products toward specific clinical problems as well as biological targets. (author)

  12. Animal Research on Nicotine Reduction: Current Evidence and Research Gaps.

    Science.gov (United States)

    Smith, Tracy T; Rupprecht, Laura E; Denlinger-Apte, Rachel L; Weeks, Jillian J; Panas, Rachel S; Donny, Eric C; Sved, Alan F

    2017-09-01

    A mandated reduction in the nicotine content of cigarettes may improve public health by reducing the prevalence of smoking. Animal self-administration research is an important complement to clinical research on nicotine reduction. It can fill research gaps that may be difficult to address with clinical research, guide clinical researchers about variables that are likely to be important in their own research, and provide policy makers with converging evidence between clinical and preclinical studies about the potential impact of a nicotine reduction policy. Convergence between clinical and preclinical research is important, given the ease with which clinical trial participants can access nonstudy tobacco products in the current marketplace. Herein, we review contributions of preclinical animal research, with a focus on rodent self-administration, to the science of nicotine reduction. Throughout this review, we highlight areas where clinical and preclinical research converge and areas where the two differ. Preclinical research has provided data on many important topics such as the threshold for nicotine reinforcement, the likelihood of compensation, moderators of the impact of nicotine reduction, the impact of environmental stimuli on nicotine reduction, the impact of nonnicotine cigarette smoke constituents on nicotine reduction, and the impact of nicotine reduction on vulnerable populations. Special attention is paid to current research gaps including the dramatic rise in alternative tobacco products, including electronic nicotine delivery systems (ie, e-cigarettes). The evidence reviewed here will be critical for policy makers as well as clinical researchers interested in nicotine reduction. This review will provide policy makers and clinical researchers interested in nicotine reduction with an overview of the preclinical animal research conducted on nicotine reduction and the regulatory implications of that research. The review also highlights the utility of

  13. Plasma-current structures of plasma focus during the current disruption

    International Nuclear Information System (INIS)

    Krokhin, O.N.; Kalachev, N.V.; Malafeev, Yu.S.; Nikulin, V.Ya; Polukhin, S.N.; Tsybenko, S.P.

    2000-01-01

    The results are presented of an investigation of the plasma structures arising during the current disruption in the Dense Plasma Focus (DPF). The study was performed using the laser-shadow and interferometry methods together with measurements of current and X-ray radiation. An analysis of the experimental results shows that for the construction of a multi mega-amperes current disruption device, the Filippov type of DPF (in comparison with the Mather type) is to be preferred since the processes occurring in the X-ray regime are much faster than in the pinch regime, and this type of plasma focus is geometrically more suitable for the assembly of such a current disrupter.This disrupter is now under construction, based on the 'Tulip' DPF installation

  14. Cell Phones: Current Research Results

    Science.gov (United States)

    ... NAS Report - Identification of Research Needs Relating to Potential Biological or Adverse Health Effects of Wireless Communication Devices World Health Organization: Electromagnetic Fields and Public Health: Mobile Phones International Agency for Research on Cancer Press ...

  15. Medical Robots: Current Systems and Research Directions

    Directory of Open Access Journals (Sweden)

    Ryan A. Beasley

    2012-01-01

    Full Text Available First used medically in 1985, robots now make an impact in laparoscopy, neurosurgery, orthopedic surgery, emergency response, and various other medical disciplines. This paper provides a review of medical robot history and surveys the capabilities of current medical robot systems, primarily focusing on commercially available systems while covering a few prominent research projects. By examining robotic systems across time and disciplines, trends are discernible that imply future capabilities of medical robots, for example, increased usage of intraoperative images, improved robot arm design, and haptic feedback to guide the surgeon.

  16. Current and Perspective Applications of Dense Plasma Focus Devices

    Science.gov (United States)

    Gribkov, V. A.

    2008-04-01

    Dense Plasma Focus (DPF) devices' applications, which are intended to support the main-stream large-scale nuclear fusion programs (NFP) from one side (both in fundamental problems of Dense Magnetized Plasma physics and in its engineering issues) as well as elaborated for an immediate use in a number of fields from the other one, are described. In the first direction such problems as self-generated magnetic fields, implosion stability of plasma shells having a high aspect ratio, etc. are important for the Inertial Confinement Fusion (ICF) programs (e.g. as NIF), whereas different problems of current disruption phenomenon, plasma turbulence, mechanisms of generation of fast particles and neutrons in magnetized plasmas are of great interest for the large devices of the Magnetic Plasma Confinement—MPC (e.g. as ITER). In a sphere of the engineering problems of NFP it is shown that in particular the radiation material sciences have DPF as a very efficient tool for radiation tests of prospect materials and for improvement of their characteristics. In the field of broad-band current applications some results obtained in the fields of radiation material sciences, radiobiology, nuclear medicine, express Neutron Activation Analysis (including a single-shot interrogation of hidden illegal objects), dynamic non-destructive quality control, X-Ray microlithography and micromachining, and micro-radiography are presented. As the examples of the potential future applications it is proposed to use DPF as a powerful high-flux neutron source to generate very powerful pulses of neutrons in the nanosecond (ns) range of its duration for innovative experiments in nuclear physics, for the goals of radiation treatment of malignant tumors, for neutron tests of materials of the first wall, blankets and NFP device's constructions (with fluences up to 1 dpa per a year term), and ns pulses of fast electrons, neutrons and hard X-Rays for brachytherapy.

  17. Current and Perspective Applications of Dense Plasma Focus Devices

    International Nuclear Information System (INIS)

    Gribkov, V. A.

    2008-01-01

    Dense Plasma Focus (DPF) devices' applications, which are intended to support the main-stream large-scale nuclear fusion programs (NFP) from one side (both in fundamental problems of Dense Magnetized Plasma physics and in its engineering issues) as well as elaborated for an immediate use in a number of fields from the other one, are described. In the first direction such problems as self-generated magnetic fields, implosion stability of plasma shells having a high aspect ratio, etc. are important for the Inertial Confinement Fusion (ICF) programs (e.g. as NIF), whereas different problems of current disruption phenomenon, plasma turbulence, mechanisms of generation of fast particles and neutrons in magnetized plasmas are of great interest for the large devices of the Magnetic Plasma Confinement--MPC (e.g. as ITER). In a sphere of the engineering problems of NFP it is shown that in particular the radiation material sciences have DPF as a very efficient tool for radiation tests of prospect materials and for improvement of their characteristics. In the field of broad-band current applications some results obtained in the fields of radiation material sciences, radiobiology, nuclear medicine, express Neutron Activation Analysis (including a single-shot interrogation of hidden illegal objects), dynamic non-destructive quality control, X-Ray microlithography and micromachining, and micro-radiography are presented. As the examples of the potential future applications it is proposed to use DPF as a powerful high-flux neutron source to generate very powerful pulses of neutrons in the nanosecond (ns) range of its duration for innovative experiments in nuclear physics, for the goals of radiation treatment of malignant tumors, for neutron tests of materials of the first wall, blankets and NFP device's constructions (with fluences up to 1 dpa per a year term), and ns pulses of fast electrons, neutrons and hard X-Rays for brachytherapy

  18. Auditing as Institutional Research: A Qualitative Focus.

    Science.gov (United States)

    Fetterman, David M.

    1991-01-01

    Internal institutional auditing can improve effectiveness and efficiency and protect an institution's assets. Many of the concepts and techniques used to analyze higher education institutions are qualitative in nature and suited to institutional research, including fiscal, operational, data-processing, investigative, management consulting,…

  19. Focus on uranium research in Senegal

    International Nuclear Information System (INIS)

    Kanoute, M.

    2014-01-01

    Two periods stand out in the history of mining exploration for uranium in Senegal: • 1957 - 1965 in the context of a general inventory of the uranium potential of Africa, which is also the time that the large deposits of Niger and Gabon were discovered; • 1973 to the present, is characterized by surveys more focused on specific topics such as Birrimian Superior Precambrian Sedimentary, Secondary and Tertiary Phosphates. The collapse of uranium price that began since 1980 calls into question the validity of these surveys on areas away from the coast that lack infrastructure and forces the elimination of targets where there is little hope of finding high enough concentrations of uranium for possible mining.

  20. Current strategies for mobilome research

    OpenAIRE

    J?rgensen, Tue S.; Kiil, Anne S.; Hansen, Martin A.; S?rensen, S?ren J.; Hansen, Lars H.

    2015-01-01

    Mobile genetic elements (MGEs) are pivotal for bacterial evolution and adaptation, allowing shuffling of genes even between distantly related bacterial species. The study of these elements is biologically interesting as the mode of genetic propagation is kaleidoscopic and important, as MGEs are the main vehicles of the increasing bacterial antibiotic resistance that causes thousands of human deaths each year. The study of MGEs has previously focused on plasmids from individual isolates, but the...

  1. Current Research in Southeast Asia.

    Science.gov (United States)

    Beh, Yolanda

    1990-01-01

    Summaries of eight language-related research projects are presented from Brunei Darussalam, Indonesia, Malaysia, and Singapore. Topics include children's reading, nonstandard spoken Indonesian, English speech act performance, classroom verbal interaction, journal writing, and listening comprehension. (LB)

  2. Current concepts in cancer research

    OpenAIRE

    Ivan Kok Seng Yap; Ammu Kutty Radhakrishnan; Chee Onn Leong

    2013-01-01

    Cancer research is an extremely broadtopic covering many scientific disciplines includingbiology (e.g. biochemistry and signal transduction),chemistry (e.g. drug discover and development),physics (e.g. diagnostic devices) and even computerscience (e.g. bioinformatics). Some would argue thatcancer research will continue in much the same wayas it is by adding further layers of complexity to thescientific knowledge that is already complex and almostbeyond measure. But we anticipate that cancer r...

  3. Mediterranea Forecasting System: a focus on wave-current coupling

    Science.gov (United States)

    Clementi, Emanuela; Delrosso, Damiano; Pistoia, Jenny; Drudi, Massimiliano; Fratianni, Claudia; Grandi, Alessandro; Pinardi, Nadia; Oddo, Paolo; Tonani, Marina

    2016-04-01

    The Mediterranean Forecasting System (MFS) is a numerical ocean prediction system that produces analyses, reanalyses and short term forecasts for the entire Mediterranean Sea and its Atlantic Ocean adjacent areas. MFS became operational in the late 90's and has been developed and continuously improved in the framework of a series of EU and National funded programs and is now part of the Copernicus Marine Service. The MFS is composed by the hydrodynamic model NEMO (Nucleus for European Modelling of the Ocean) 2-way coupled with the third generation wave model WW3 (WaveWatchIII) implemented in the Mediterranean Sea with 1/16 horizontal resolution and forced by ECMWF atmospheric fields. The model solutions are corrected by the data assimilation system (3D variational scheme adapted to the oceanic assimilation problem) with a daily assimilation cycle, using a background error correlation matrix varying seasonally and in different sub-regions of the Mediterranean Sea. The focus of this work is to present the latest modelling system upgrades and the related achieved improvements. In order to evaluate the performance of the coupled system a set of experiments has been built by coupling the wave and circulation models that hourly exchange the following fields: the sea surface currents and air-sea temperature difference are transferred from NEMO model to WW3 model modifying respectively the mean momentum transfer of waves and the wind speed stability parameter; while the neutral drag coefficient computed by WW3 model is passed to NEMO that computes the turbulent component. In order to validate the modelling system, numerical results have been compared with in-situ and remote sensing data. This work suggests that a coupled model might be capable of a better description of wave-current interactions, in particular feedback from the ocean to the waves might assess an improvement on the prediction capability of wave characteristics, while suggests to proceed toward a fully

  4. Current Research in Southeast Asia.

    Science.gov (United States)

    Beh, Yolanda

    1991-01-01

    Summaries of seven language-related research projects are presented from Malaysia, Philippines, Singapore, and Thailand. Topics include a lexicon of Kelabit, cognitive theory for second-language acquisition, academic writing in Filipino, cultural politics of English instruction, use of conjunctions, and communicative grammar. (LB)

  5. Current Research in Southeast Asia.

    Science.gov (United States)

    Beh, Yolanda

    1992-01-01

    Summaries of eight language-related research projects are presented from Brunei Darussalam, Indonesia, Malaysia, Singapore, and Thailand. Topics include a sociolinguistic profile, teacher and learner views of language lessons, Malay-accented English and employability, reading difficulties, language culture disjunction, placement interviews, and…

  6. Current Research in Southeast Asia.

    Science.gov (United States)

    Beh, Yolanda

    1991-01-01

    Summaries of five language-related research projects are presented from Malaysia, Singapore, and Thailand. Topics include teaching/learning Bahasa Malaysia; English-language programs in Malaysian teacher education colleges; interlanguage variability in verbs; reading/writing theories; and cross-cultural strategies and English in written business…

  7. Current strategies for mobilome research

    Directory of Open Access Journals (Sweden)

    Tue Sparholt Jørgensen

    2015-01-01

    Full Text Available Mobile genetic elements (MGE are pivotal for bacterial evolution and adaptation, allowing shuffling of genes even between distantly related bacterial species. The study of MGEs is biologically interesting as the mode of genetic propagation is kaleidoscopic and important, as MGEs are the main vehicles of the increasing bacterial antibiotic resistance that causes thousands of human deaths each year. The study of MGEs has previously focused on plasmids from individual isolates, but the revolution in sequencing technology has allowed the study of mobile genomic elements of entire communities using metagenomic approaches. The problem in using metagenomic sequencing for the study of MGEs is that plasmids and other mobile elements only comprise a small fraction of the total genetic content that are difficult to separate from chromosomal DNA based on sequence alone. Several different approaches have been proposed that specifically enrich plasmid DNA from community samples. Here, we review recent approaches used to study entire plasmid pools from complex environments, and point out possible future developments for and pitfalls of these approaches. Further, we discuss the use of the PacBio long-read sequencing technology for MGE discovery.

  8. Current strategies for mobilome research.

    Science.gov (United States)

    Jørgensen, Tue S; Kiil, Anne S; Hansen, Martin A; Sørensen, Søren J; Hansen, Lars H

    2014-01-01

    Mobile genetic elements (MGEs) are pivotal for bacterial evolution and adaptation, allowing shuffling of genes even between distantly related bacterial species. The study of these elements is biologically interesting as the mode of genetic propagation is kaleidoscopic and important, as MGEs are the main vehicles of the increasing bacterial antibiotic resistance that causes thousands of human deaths each year. The study of MGEs has previously focused on plasmids from individual isolates, but the revolution in sequencing technology has allowed the study of mobile genomic elements of entire communities using metagenomic approaches. The problem in using metagenomic sequencing for the study of MGEs is that plasmids and other mobile elements only comprise a small fraction of the total genetic content that are difficult to separate from chromosomal DNA based on sequence alone. The distinction between plasmid and chromosome is important as the mobility and regulation of genes largely depend on their genetic context. Several different approaches have been proposed that specifically enrich plasmid DNA from community samples. Here, we review recent approaches used to study entire plasmid pools from complex environments, and point out possible future developments for and pitfalls of these approaches. Further, we discuss the use of the PacBio long-read sequencing technology for MGE discovery.

  9. Current Research Status of Allelopathy

    Directory of Open Access Journals (Sweden)

    AHMAD JUNAEDI

    2006-06-01

    Full Text Available The term of allelopathy refers to chemical interactions (inhibitory or stimulatory between plants, between plants and microorganisms, and between microorganisms. The wealth of information on the processes, procedures, and practices of allelopathy has contributed to understanding this field of science. Recently, researches of allelopathy have been conducted in laboratory, greenhouse, and field with multifaceted standpoint in some concerning area: (i allelochemicals identifications and screening test; (ii ecological and physiological aspects of allelopathy; (iii genetic studies and the possibilities of using plant breeding or genetic manipulation to enhance allelopathic varieties; (iv the use of allelopathic potential in the biological control, including as natural pesticide, of weeds and plant diseases as eco-friendly approach for sustainable agriculture scheme.

  10. Current Issues in LPP Research and Their Impact on Society

    Science.gov (United States)

    Darquennes, Jeroen

    2013-01-01

    After a very broad description of what language policy and planning is about this paper presents an overview of some of the current preoccupations of researchers focusing on language policy and planning as one of the blooming fields of applied linguistics. The current issues in language policy and planning research that are dealt with include…

  11. Current status of nuclear safety research

    International Nuclear Information System (INIS)

    Anon.

    1977-01-01

    Efforts at nuclear safety research have expanded year by year in Japan, in term of money and technical achievement. The Atomic Energy Commission set last year the five year nuclear safety research program, a guideline by which various research institutes will be able to develop their own efforts in a concerted manner. From the results of the nuclear safety research which cover very wide areas ranging from reactor engineering safety, safety of nuclear fuel cycle facilities, prevention of radiation hazards to the adequate treatment and disposal of radioactive wastes, AIJ hereafter focuses of LWR engineering safety and prevents two articles, one introducing the current results of the NSSR program developed by JAERI and the other reporting the LWR reliability demonstration testing projects being promoted by MITI. The outline of these demonstration tests was reported in this report. The tests consist of earthquake resistance reliability test of nuclear power plants, steam generator reliability tests, valve integrity tests, fuel assembly reliability tests, reliability tests of heat affected zones and reliability tests of pumps. (Kobatake, H.)

  12. Current state of low-cycle fatigue research based on multiaxial stress intensity and its challenges. Part 1. Focusing on low-cycle fatigue strength evaluation method of elbow piping subjected to in-plane cyclic bending displacement load

    International Nuclear Information System (INIS)

    Urabe, Yoshio

    2017-01-01

    The R and D of fatigue strength at multiaxial stress intensity is recognized to become extremely important in the future in terms of the elaboration of low-cycle fatigue evaluation of various structures including piping systems and reflection on those standards. This paper focuses on the evaluation method developed by the author, namely cumulative damage rule in consideration of multiaxial stress intensity, and explains the concept and the results of verification and evaluation. It also discusses the engineering problems of the current low cycle fatigue assessment technology that were clarified in the process of developing low-cycle fatigue assessment method based on multiaxial stress intensity. The conservative lifespan and somewhat more conservative actual lifetime of elbow piping can be estimated by the conventional 'revised universal slope method' and 'advanced revised universal slope method.' However, these are empirical rules, and the theoretical basis is not clear. From 'cumulative damage rule in consideration of multiaxial stress intensity,' the author calculated furthermore 'low cycle fatigue evaluation formula based on cumulative damage rule in consideration of multi-axial stress intensity,' and examined it. As a result, an evaluation formula that can reasonably assume the equivalent thermoplastic strain range could be obtained at half of the repeat count as targeted. Furthermore, at the stage where future high precision FEM analysis can be used, direct low-cycle fatigue life curve can be established. (A.O.)

  13. Leadership: current theories, research, and future directions.

    Science.gov (United States)

    Avolio, Bruce J; Walumbwa, Fred O; Weber, Todd J

    2009-01-01

    This review examines recent theoretical and empirical developments in the leadership literature, beginning with topics that are currently receiving attention in terms of research, theory, and practice. We begin by examining authentic leadership and its development, followed by work that takes a cognitive science approach. We then examine new-genre leadership theories, complexity leadership, and leadership that is shared, collective, or distributed. We examine the role of relationships through our review of leader member exchange and the emerging work on followership. Finally, we examine work that has been done on substitutes for leadership, servant leadership, spirituality and leadership, cross-cultural leadership, and e-leadership. This structure has the benefit of creating a future focus as well as providing an interesting way to examine the development of the field. Each section ends with an identification of issues to be addressed in the future, in addition to the overall integration of the literature we provide at the end of the article.

  14. Navy Telemedicine: Current Research and Future Directions

    National Research Council Canada - National Science Library

    Reed, Cheryl

    2002-01-01

    .... This report reviews military and civilian models for evaluating telemedicine systems in order to determine future directions for Navy telemedicine research within the current funding environment...

  15. Sexting: Current Research Gaps and Legislative Issues

    OpenAIRE

    Ngo, Fawn; Jaishankar, K; Agustina, Jose R.

    2017-01-01

    'Sexting, the portmanteau of Sex and Texting, has become a hot topic of debate between the legislators, researchers, educators, parents and teens' (Jaishankar, 2009, para 1). In spite of the considerable and growing body of literature on sexting, there are significant gaps in the current research. A review of research to date also reveals a dearth of cross-national and cross-cultural research on the topic of sexting. Notably, legal and ethical issues abound with the current method for punishi...

  16. 21 CFR 312.86 - Focused FDA regulatory research.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Focused FDA regulatory research. 312.86 Section 312.86 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... Severely-debilitating Illnesses § 312.86 Focused FDA regulatory research. At the discretion of the agency...

  17. MR-guided focused ultrasound. Current and future applications

    International Nuclear Information System (INIS)

    Trumm, C.G.; Peller, M.; Clevert, D.A.; Stahl, R.; Reiser, M.; Napoli, A.; Matzko, M.

    2013-01-01

    High-intensity focused ultrasound (synonyms FUS and HIFU) under magnetic resonance imaging (MRI) guidance (synonyms MRgFUS and MR-HIFU) is a completely non-invasive technology for accurate thermal ablation of a target tissue while neighboring tissues and organs are preserved. The combination of FUS with MRI for planning, (near) real-time monitoring and outcome assessment of treatment markedly enhances the safety of the procedure. The MRgFUS procedure is clinically established in particular for the treatment of symptomatic uterine fibroids, followed by palliative ablation of painful bone metastases. Furthermore, promising results have been shown for the treatment of adenomyosis, malignant tumors of the prostate, breast and liver and for various intracranial applications, such as thermal ablation of brain tumors, functional neurosurgery and transient disruption of the blood-brain barrier. (orig.) [de

  18. [MR-guided focused ultrasound. Current and future applications].

    Science.gov (United States)

    Trumm, C G; Napoli, A; Peller, M; Clevert, D-A; Stahl, R; Reiser, M; Matzko, M

    2013-03-01

    High-intensity focused ultrasound (synonyms FUS and HIFU) under magnetic resonance imaging (MRI) guidance (synonyms MRgFUS and MR-HIFU) is a completely non-invasive technology for accurate thermal ablation of a target tissue while neighboring tissues and organs are preserved. The combination of FUS with MRI for planning, (near) real-time monitoring and outcome assessment of treatment markedly enhances the safety of the procedure. The MRgFUS procedure is clinically established in particular for the treatment of symptomatic uterine fibroids, followed by palliative ablation of painful bone metastases. Furthermore, promising results have been shown for the treatment of adenomyosis, malignant tumors of the prostate, breast and liver and for various intracranial applications, such as thermal ablation of brain tumors, functional neurosurgery and transient disruption of the blood-brain barrier.

  19. Focus Group in Community Mental Health Research: Need for Adaption.

    Science.gov (United States)

    Zupančič, Vesna; Pahor, Majda; Kogovšek, Tina

    2018-04-27

    The article presents an analysis of the use of focus groups in researching community mental health users, starting with the reasons for using them, their implementation in mental health service users' research, and the adaptations of focus group use when researching the experiences of users. Based on personal research experience and a review of scientific publications in the Google Scholar, Web of Science, ProQuest, EBSCOhost, and Scopus databases, 20 articles published between 2010 and 2016 were selected for targeted content analysis. A checklist for reporting on the use of focus groups with community mental health service users, aiming to improve the comparability, verifiability and validity was developed. Adaptations of the implementation of focus groups in relation to participants' characteristics were suggested. Focus groups are not only useful as a scientific research technique, but also for ensuring service users' participation in decision-making in community mental health and evaluating the quality of the mental health system and services .

  20. Revisiting the use of focus group in social research

    Directory of Open Access Journals (Sweden)

    Betina Freidin

    2016-06-01

    Full Text Available The methodological reflections on focus groups presented in this article draw from a research project on middle-class people living in Metropolitan Buenos Aires. The study addresses health discourses and practices in the contemporary scenario characterized by the diversification of specialists, the growing media coverage of recommendations of healthy living and wellbeing, the implementation of public policies on health promotion, and the expansion of the industry of related products and services.  The objective of the article is to reflect, based on our fieldwork experience, on two aspects that have received special attention in the recent methodological literature: the criteria to compose the groups and their consequences on the conversational dynamic, and the strategies to account for the group interaction in data analysis. Included in the latter, we explore the potential of GF research to observe health identity work. We frame our study and the decisions about design issues into the current debates on the variety of uses of the research group methodology.

  1. The use of focused ethnography in nursing research.

    Science.gov (United States)

    Cruz, Edward Venzon; Higginbottom, Gina

    2013-03-01

    To provide an overview of the relevance and strengths of focused ethnography in nursing research. The paper provides descriptions of focused ethnography and discusses using exemplars to show how focused ethnographies can enhance and understand nursing practice. Orthodox ethnographic approaches may not always be suitable or desirable for research in diverse nursing contexts. Focused ethnography has emerged as a promising method for applying ethnography to a distinct issue or shared experience in cultures or sub-cultures and in specific settings, rather than throughout entire communities. Unfortunately, there is limited guidance on using focused ethnography, particularly as applied to nursing research. Research studies performed by nurses using focused ethnography are summarised to show how they fulfilled three main purposes of the genre in nursing research. Additional citations are provided to help demonstrate the versatility of focused ethnography in exploring distinct problems in a specific context in different populations and groups of people. The unique role that nurses play in health care, coupled with their skills in enquiry, can contribute to the further development of the discipline. Focused ethnography offers an opportunity to gain a better understanding and appreciation of nursing as a profession, and the role it plays in society. Focused ethnography has emerged as a relevant research methodology that can be used by nurse researchers to understand specific societal issues that affect different facets of nursing practice. As nurse researchers endeavour to understand experiences in light of their health and life situations, focused ethnography enables them to understand the interrelationship between people and their environments in the society in which they live.

  2. Visual neglect following stroke: current concepts and future focus.

    Science.gov (United States)

    Ting, Darren S J; Pollock, Alex; Dutton, Gordon N; Doubal, Fergus N; Ting, Daniel S W; Thompson, Michelle; Dhillon, Baljean

    2011-01-01

    Visual neglect is a common, yet frequently overlooked, neurological disorder following stroke characterized by a deficit in attention and appreciation of stimuli on the contralesional side of the body. It has a profound functional impact on affected individuals. A assessment and management of this condition are hindered, however, by the lack of professional awareness and clinical guidelines. Recent evidence suggests that the underlying deficit in visual attention is due to a disrupted internalized representation of the outer world rather than a disorder of sensory inputs. Dysfunction of the cortical domains and white-matter tracts, as well as inter-hemispheric imbalance, have been implicated in the various manifestations of visual neglect. Optimal diagnosis requires careful history-taking from the patient, family, and friends, in addition to clinical assessment with the line bisection test, the star cancellation test, and the Catherine Bergego Scale. Early recognition and prompt rehabilitation employing a multidisciplinary approach is desirable. Although no treatment has been definitively shown to be of benefit, those with promise include prism adaptation, visual scanning therapy, and virtual reality-based techniques. Further high quality research to seek optimum short- and long-term rehabilitative strategies for visual neglect is required. Copyright © 2011 Elsevier Inc. All rights reserved.

  3. Research Timeline: Form-Focused Instruction and Second Language Acquisition

    Science.gov (United States)

    Nassaji, Hossein

    2016-01-01

    This article provides a timeline of research on form-focused instruction (FFI). Over the past 40 years, research on the role of instruction has undergone many changes. Much of the early research concentrated on determining whether formal instruction makes any difference in the development of learner language. This question was motivated in part by…

  4. Plutonium Focus Area research and development plan. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-11-01

    The Department of Energy (DOE) committed to a research and development program to support the technology needs for converting and stabilizing its nuclear materials for safe storage. The R and D Plan addresses five of the six material categories from the 94-1 Implementation Plan: plutonium (Pu) solutions, plutonium metals and oxides, plutonium residues, highly enriched uranium, and special isotopes. R and D efforts related to spent nuclear fuel (SNF) stabilization were specifically excluded from this plan. This updated plan has narrowed the focus to more effectively target specific problem areas by incorporating results form trade studies. Specifically, the trade studies involved salt; ash; sand, slag, and crucible (SS and C); combustibles; and scrub alloy. The plan anticipates possible disposition paths for nuclear materials and identifies resulting research requirements. These requirements may change as disposition paths become more certain. Thus, this plan represents a snapshot of the current progress and will continue to be updated on a regular basis. The paper discusses progress in safeguards and security, plutonium stabilization, special isotopes stabilization, highly-enriched uranium stabilization--MSRE remediation project, storage technologies, engineered systems, core technology, and proposed DOE/Russian technology exchange projects.

  5. Plutonium Focus Area research and development plan. Revision 1

    International Nuclear Information System (INIS)

    1996-11-01

    The Department of Energy (DOE) committed to a research and development program to support the technology needs for converting and stabilizing its nuclear materials for safe storage. The R and D Plan addresses five of the six material categories from the 94-1 Implementation Plan: plutonium (Pu) solutions, plutonium metals and oxides, plutonium residues, highly enriched uranium, and special isotopes. R and D efforts related to spent nuclear fuel (SNF) stabilization were specifically excluded from this plan. This updated plan has narrowed the focus to more effectively target specific problem areas by incorporating results form trade studies. Specifically, the trade studies involved salt; ash; sand, slag, and crucible (SS and C); combustibles; and scrub alloy. The plan anticipates possible disposition paths for nuclear materials and identifies resulting research requirements. These requirements may change as disposition paths become more certain. Thus, this plan represents a snapshot of the current progress and will continue to be updated on a regular basis. The paper discusses progress in safeguards and security, plutonium stabilization, special isotopes stabilization, highly-enriched uranium stabilization--MSRE remediation project, storage technologies, engineered systems, core technology, and proposed DOE/Russian technology exchange projects

  6. Current situation on the glueball research

    International Nuclear Information System (INIS)

    Shen Qixing

    1991-01-01

    The current situation on the glueball research is reviewed. The emphases are some qualitative guidances to identify the glueball and several possible candidate states for the glueball which have been discovered in the experiments

  7. Transfer and focusing of high current relativistic electron beams on a target

    International Nuclear Information System (INIS)

    Baranchikov, E.I.; Gordeev, A.V.; Koba, Yu.V.; Korolev, V.D.; Penkina, V.S.; Rudakov, L.I.; Smirnov, V.P.; Sukhov, A.D.; Tarumov, E.Z.; Bakshaeev, Yu.L.

    Research is being conducted at the I. V. Kurchatov Atomic Energy Institute to investigate possibilities of creating a pulsed thermonuclear reactor based on REBs; this work involves the creation of a multimodel system using vacuum lines for transferring energy and an acute angled external magnetic field for transferring electron beams to the target. A field of this configuration can be used at the same time for accumulating a ''cloud'' of relativistic protons around the target for purposes of irradiating them. This alternative solution of the problem of target irradiation, instead of focusing beams directly on it, may prove to be highly promising. Experiments are described which were conducted recently on high current electron accelerators ''URAL'', ''MS'' and others and which were directed at investigating possibilities of transferring and focusing high current REBs, as well as effective transmission of electromagnetic energy using vacuum lines at considerable distances

  8. Research and Its Relationship to Nurse Education: Focus and Capacity.

    Science.gov (United States)

    Newell, Robert

    2002-01-01

    Examination of two British mental health journals and a government document on the future of nursing found a lack of focus on clinical research and little reference to the role of research and development in practice. The increasing importance of evidence-based practice demands a strategy for developing nurses' capacity to understand, undertake,…

  9. Image Information Retrieval: An Overview of Current Research

    OpenAIRE

    Abby A. Goodrum

    2000-01-01

    This paper provides an overview of current research in image information retrieval and provides an outline of areas for future research. The approach is broad and interdisciplinary and focuses on three aspects of image research (IR): text-based retrieval, content-based retrieval, and user interactions with image information retrieval systems. The review concludes with a call for image retrieval evaluation studies similar to TREC.

  10. Design Research with a Focus on Learning Processes: An Overview on Achievements and Challenges

    Science.gov (United States)

    Prediger, Susanne; Gravemeijer, Koeno; Confrey, Jere

    2015-01-01

    Design research continues to gain prominence as a significant methodology in the mathematics education research community. This overview summarizes the origins and the current state of design research practices focusing on methodological requirements and processes of theorizing. While recognizing the rich variations in the foci and scale of design…

  11. The Research Focus of Nations: Economic vs. Altruistic Motivations.

    Science.gov (United States)

    Klavans, Richard; Boyack, Kevin W

    2017-01-01

    What motivates the research strategies of nations and institutions? We suggest that research primarily serves two masters-altruism and economic growth. Some nations focus more research in altruistic (or non-economic) fields while others focus more research in fields associated with economic growth. What causes this difference? Are there characteristics that would suggest why a nation is more aligned with altruism or economic growth? To answer this question, we have identified nine major fields of research by analyzing the publication activity of 4429 institutions using Scopus data. Two fields of research are clearly altruistic (there is relatively little involvement by industry) and two fields are clearly aligned with economic growth. The altruistic vs. economic nature of nations based on their publication profiles across these fields is correlated with national indicators on wealth, education, capitalism, individualism, power, religion, and language. While previous research has suggested that national research strategy is aligned with national wealth, our analysis shows that national wealth is not highly correlated with the tradeoff between altruistic and economic motives. Instead, the tradeoff is largely captured by a culture of individualism. Accordingly, implications for national research strategies are discussed.

  12. Digital library research : current developments and trends

    OpenAIRE

    Shiri, Ali

    2003-01-01

    This column gives an overview of current trends in digital library research under the following headings: digital library architecture, systems, tools and technologies; digital content and collections; metadata; interoperability; standards; knowledge organisation systems; users and usability; legal, organisational, economic, and social issues in digital libraries.

  13. Research on high beam-current accelerators

    International Nuclear Information System (INIS)

    Keefe, D.

    1981-01-01

    In this review of research being undertaken at present in the US on accelerating devices and concepts of a novel nature, both non-collective systems, including high-current rf linacs and a variety of induction linacs, and also collective systems are considered. (U.K.)

  14. Pressure ulcer research : current and future perspectives

    NARCIS (Netherlands)

    Bader, D.L.; Bouten, C.V.C.; Colin, D.; Oomens, C.W.J.

    2005-01-01

    This book provides an up-to-date scientific account of all aspects related to pressure ulcers and pressure ulcer research, as well as evidence-based knowledge of pressure ulcer aetiology. Further, it describes current and future tools for evaluating patients at risk. It comprises 20 chapters by

  15. Clinical Perspective Qualitative adolescent health researchfocus ...

    African Journals Online (AJOL)

    This paper introduces nine steps that are recommended in conducting focus group discussions in rural communities and gives an example of how they can appropriately and fruitfully be employed in adolescent health behavioural research. The paper also reviewed issues related to methods of data collection, data analysis, ...

  16. [Physiotherapeutic care marketing research: current state-of-the art].

    Science.gov (United States)

    Babaskin, D V

    2011-01-01

    Successful introduction of modern technologies into the national health care systems strongly depends on the current pharmaceutical market situation. The present article is focused on the peculiarities of marketing research with special reference to physiotherapeutic services and commodities. Analysis of the structure and sequence of marketing research processes is described along with the methods applied for the purpose including their support by the use of Internet resources and technologies.

  17. Current activities at the MIT Research Reactor

    International Nuclear Information System (INIS)

    Hu Linwen; Bernard, John A.; Harling, Otto K.; Kohse, Gordon E.; Ames, Michael; Olmez, Ilhan

    1998-01-01

    The MIT Research Reactor (MITR) is a MW nuclear research reactor that is owned and operated by the Massachusetts Institute of Technology to further its educational and research goals at both the undergraduate and graduate level. The reactor first achieved criticality in 1958. It was largely rebuilt in 1973/1974 by MIT staff and students, and its current license expires in August 1999. The current facility, which is designated as the MITR-H, uses a compact core with finned, aluminum-clad, plate-type fuel that is cooled and moderated by light water and reflected by heavy water. The reactor core can hold twenty-seven fuel elements. However, the normal configuration is twenty-four elements. A maximum of four fuel elements can be replaced with in-core experimental facilities. A unique feature of the MITR-II's design is that fixed absorber plates can be inserted in the upper half of the core. These cause the flux to peak in the lower half which benefits experimenters and also facilitates a fuel strategy that involves inversion of fuel elements midway through their life cycle. The MITR-II currently operates continuously for four weeks followed by shutdown of a few days for maintenance. This paper provides an overview of current activities at the MITR including preparations for re-licensing. The status of an on-going Phase-I clinical trial of boron neutron capture therapy for both glioblastoma multiforme and metastatic melanoma is described as well as the design of a fission converter facility for BNCT. Environmental research using neutron activation analysis is summarized as well as in-pile research focussed on LWR water chemistry and structural materials. (author)

  18. Focusing Information Systems Post-Graduate Research Projects

    Directory of Open Access Journals (Sweden)

    Gail Ridley

    1996-11-01

    Full Text Available This paper reports on an investigation of mechanisms that assist Information Systems post-graduate research students to focus their projects. An evaluation is presented of the experiences of Information Systems research students in focussing their research projects based on a survey conducted of students who participated in two of the first three Information Systems doctoral consortia to be held in Australia. The survey sought to determine whether a doctoral consortium or 'systematic expert review' is the most valuable mechanism for focussing a research proposal. Systematic expert review was considered by the students to be more effective than the doctoral consortium process for the purpose of focussing their research project proposals.

  19. Focus Group Interview in Family Practice Research: Implementing a qualitative research method

    OpenAIRE

    Wood, Marjorie L.

    1992-01-01

    Focus group interviews, described as a qualitative research method with good potential in family medicine, are traced from their origins in market research to their growing role in sociology and medicine. Features of this method are described, including design, conduct, and analysis. Both proven and potential areas for primary care research using focus groups are outlined.

  20. Integrated fundamental research on current collection

    Science.gov (United States)

    Kuhlmann-Wilsdorf, Doris; Tran, Leo

    1993-06-01

    The aim of our research was to add to the basic understanding in the area of current collection with particular emphasis on topics likely to benefit practical objectives. Under sponsorship of this contract, 23 papers were published in the international literature. Additionally, 13 invited lectures and 11 contributed lectures on various aspects of this research were delivered at universities, research laboratories, and international conferences by the principal investigator and co-workers. The development of a novel metal fiber material for sliding electrical contacts was continued with much success. This is expected to become very useful for making metal fiber brushed for homopolar motors/generators, as well as for EML armatures. Included in this report are title pages (and abstracts) for the 23 published papers.

  1. Agriculture for improved nutrition: the current research landscape.

    Science.gov (United States)

    Turner, Rachel; Hawkes, Corinna; Jeff, Waage; Ferguson, Elaine; Haseen, Farhana; Homans, Hilary; Hussein, Julia; Johnston, Deborah; Marais, Debbi; McNeill, Geraldine; Shankar, Bhavani

    2013-12-01

    Concern about food security and its effect on persistent undernutrition has increased interest in how agriculture could be used to improve nutritional outcomes in developing countries. Yet the evidence base for the impact of agricultural interventions targeted at improved nutrition is currently poor. To map the extent and nature of current and planned research on agriculture for improved nutrition in order to identify gaps where more research might be useful. The research, which was conducted from April to August 2012, involved developing a conceptual framework linking agriculture and nutrition, identifying relevant research projects and programs, devising and populating a "template" with details of the research projects in relation to the conceptual framework, classifying the projects, and conducting a gap analysis. The study identified a large number of research projects covering a broad range of themes and topics. There was a strong geographic focus on sub-Saharan Africa, and many studies were explicitly concerned with nutritional impacts on women and children. Although the study revealed a diverse and growing body of research, it also identified research gaps. Few projects consider the entire evidence chain linking agricultural input or practice to nutritional outcomes. There is comparatively little current research on indirect effects of agriculture on nutrition, or the effect of policies or governance, rather than technical interventions. Most research is focused on undernutrition and small farmer households, and few studies target consumers generally, urban populations, or nutrition-related non-communicable diseases. There is very little work on the cost-effectiveness of agricultural interventions. On the basis of these findings, we make suggestions for research investment and for broader engagement of researchers and disciplines in developing approaches to design and evaluate agricultural programs for improved nutrition.

  2. The Focus on Youth Prevention and Education Research Programme

    Directory of Open Access Journals (Sweden)

    Lynette Deveaux

    2016-10-01

    Full Text Available Like many developing or transitional countries affected by the HIV epidemic, The Bahamas has been deeply committed to HIV and sexually transmitted infection reduction and continues to make great strides in controlling the epidemic within its boundaries. Encouraged by the impact of the Focus on Youth Caribbean (FOYC, a school-based HIV/AIDS prevention programme and its parenting component on Grade 6 and Grade 10 students and their parents, a team of researchers from The Bahamas and the United States sought to implement a similar programme at a national level, while simultaneously evaluating factors that impact the sustainability of sexual risk-reduction programmes like FOYC. This paper describes five research projects conducted in The Bahamas between 1998 and 2016 and includes a list of over 40 published research articles

  3. Topics in current aerosol research (part2)

    CERN Document Server

    Hidy, G M

    1972-01-01

    Topics in Current Aerosol Research, Part 2 contains some selected articles in the field of aerosol study. The chosen topics deal extensively with the theory of diffusiophoresis and thermophoresis. Also covered in the book is the mathematical treatment of integrodifferential equations originating from the theory of aerosol coagulation. The book is the third volume of the series entitled International Reviews in Aerosol Physics and Chemistry. The text offers significant understanding of the methods employed to develop a theory for thermophoretic and diffusiophoretic forces acting on spheres in t

  4. Research in Humans: Current Perspectives in Brazil

    Directory of Open Access Journals (Sweden)

    Célia Alcantara Cunha Lima

    2016-10-01

    Full Text Available This work addressed the norms of ethics for human experimentation in Brazil, operationalized by the National Research Ethics Commission (CONEP of the National Health Council (CNS. It analyzed international principles of bioethics as a theoretical framework for the Brazilian regulation. National and international publications were reviewed, by Capes periodicals, relating to historical ethical infractions, such as reflection to the current day. It analyzed the law (PL 200/2015 of the Senate, which proposes flexibilities in Brazilian legislation and concluded that the requested changes should be discussed in depth by bioethicists, scientists and Brazilian lawyers with extended discussion to society.

  5. Integrating Current Meteorological Research Through Club Fundraising

    Science.gov (United States)

    Gill, S. S.; Kauffman, C. M.

    2003-12-01

    Earth science programs whose focus is primarily an undergraduate education do not often have the funding to take students to very many conferences which could expose the student to new research as well as possible graduate programs and employment opportunities. Conferences also give the more enthusiastic and hardworking students a venue in which to present their research to the meteorological community. In addition, the California University services largely lower income counties, which make student attendance at conferences even more difficult even though the student in SW PA may be individually motivated. This issue is compounded by the fact that the Meteorology Concentration within the Earth Science department at Cal U is composed of only two full-time Professors, which limits the amount of research students can be exposed to within a classroom setting. New research ideas presented at conferences are thus an important mechanism for broadening what could be an isolated program. One way in which the meteorology program has circumvented the funding problem to a certain extent is through an active student club. With nearly 60 majors (3/4 of which are active in club activities, the meteorology club is able to execute a variety of fundraising activities. Money that is raised can then request from student services matching funds. Further money is given to clubs, which are very active not only in fundraising, but using that money for academic related activities. For the last 3 years the club budget has been in the neighborhood of \\$4500. The money has then been used to partially finance student registration and accommodation costs making conference attendance much more affordable. Normally 8-16 students attend conferences that they would otherwise not be able to attend without great expense. There are times when more than 16 students wish to attend, but travel arrangements prohibit more than 16. Moreover club money is also use to supplement student costs on a summer

  6. Ganando Confianza: Research Focus Groups with Immigrant Mexican Mothers.

    Science.gov (United States)

    Hausmann-Stabile, Carolina; Zayas, Luis H; Runes, Sandra; Abenis-Cintron, Anna; Calzada, Esther

    2011-03-01

    Immigrant families with children with developmental disabilities must be served using culturally sensitive approaches to service and research to maximize treatment benefits. In an effort to better understand cultural issues relevant to the provision of parenting programs for immigrant Mexican mothers of children with developmental disabilities, we conducted sustained focus groups through which we could learn more about our participants and thereby improve services. This paper reports on the challenges and lessons learned from these groups. We characterize the key lessons as (a) recruitment and retention is more than agreement to participate; (b) confidentiality is not just a word but an activity; (c) the complicated nature of language; (d) cultural norms shape the group process; (e) appreciating the value of taking time; and (f) gender issues and group interaction. Service providers and researchers who work with Mexican families may benefit from our experiences as they promote and develop programs and projects in the developmental disabilities field.

  7. Current status and prospects of research reactors

    International Nuclear Information System (INIS)

    Gabaraev, A.B.; Cherepnin, Yu.S.; Tretyakov, I.T.; Khmelshikov, V.V.; Dollezhal, N.A.

    2009-01-01

    Full text: The first nuclear research reactors (RR) appeared in the 1940s. Their initial purpose was to provide knowledge of the main processes associated with neutron-induced nuclear reactions. Later, the rang of problems addressed expanded substantially. Besides fundamental research in the properties of matter, such reactors are successfully used for dealing with problems in the fields of materials science, nuclear engineering, medicine, isotope production, education, etc. Over the whole period of RR fleet growth, more than six hundred nuclear research facilities were built in 70 countries of the world. As of the end of 2008, the number of Russian research reactors in service was about 20% of the globally operating RR fleet. This paper discusses the current status of the world's RR fleet and describes the capabilities of the experimental reactor facilities existing in Russia. In the 21st century, research reactors will remain in demand to solve scientific and technological problems for innovative development of society. The emerging renaissance of nuclear power, the expanding RR uses for production of isotopes and other applications, the increase in the number of countries willing to use nuclear technologies in energy production, industry and science - all contribute to a rebirth of interest in research reactors. One of the ways to improve the experimental capabilities lies in radical upgrading of the reactor facilities with qualitative changes in the main neutronic characteristics of the core. The associated design approaches are illustrated with the example of the IBR-2M reactor at the JNRI in Dubna. The imperative need restricting the spread of nuclear threat leads us to give up using highly enriched uranium in most research reactors. Development of RR fuel with reduced enrichment in uranium has been one of the priority objectives of NIKIET for many years. This paper presents the latest results obtained along these lines, as applied to pool-type research

  8. Current status of research on school refusal

    Directory of Open Access Journals (Sweden)

    Cándido J. Inglés

    2015-06-01

    Full Text Available School refusal behavior refers to the avoidance of a child attending school and/or persistent difficulty staying in the classroom throughout the school day. Based on a review of the scientific literature, the aim of this study is to describe the current state of research on school refusal, differentiating between the findings and progress made in Spain from those achieved in the international field. For this purpose, the significance of this phenomenon, in addition to associated risk factors and variables, will be reviewed in the child and youth population. In turn, the commonly used assessment methods and most recommended treatment proposals, mainly based on cognitive behavioral therapy, are discussed. The results reveal several gaps and subjects for debate in some areas of knowledge about school refusal behavior, with differences being found between Spanish and international studies. In conclusion, future studies and challenges in this field are required.

  9. Current and Future Research at DANCE

    Science.gov (United States)

    Jandel, M.; Baramsai, B.; Bredeweg, T. A.; Couture, A.; Hayes, A.; Kawano, T.; Mosby, S.; Rusev, G.; Stetcu, I.; Taddeucci, T. N.; Talou, P.; Ullmann, J. L.; Walker, C. L.; Wilhelmy, J. B.

    2015-05-01

    An overview of the current experimental program on measurements of neutron capture and neutron induced fission at the Detector for Advanced Neutron Capture Experiments (DANCE) is presented. Three major projects are currently under way: 1) high precision measurements of neutron capture cross sections on Uranium isotopes, 2) research aimed at studies of the short-lived actinide isomer production in neutron capture on 235U and 3) measurements of correlated data of fission observables. New projects include developments of auxiliary detectors to improve the capability of DANCE. We are building a compact, segmented NEUtron detector Array at DANCE (NEUANCE), which will be installed in the central cavity of the DANCE array. It will provide experimental information on prompt fission neutrons in coincidence with the prompt fission gamma-rays measured by 160 BaF2 crystals of DANCE. Unique correlated data will be obtained for neutron capture and neutron-induced fission using the DANCE-NEUANCE experimental set up in the future.

  10. A Program to Improve Student Engagement at Research-Focused Universities

    Science.gov (United States)

    Whillans, Ashley V.; Hope, Sally E.; Wylie, Lauren J.; Zhao, Bob; Souza, Michael J.

    2018-01-01

    Promoting undergraduate engagement is an important and challenging obstacle at large research-focused universities. Thus, the current study evaluated whether a peer-led program of student-geared events could improve engagement among a diverse group of psychology students early on in their degrees. We randomly assigned interested second-year…

  11. Translational toxicology: a developmental focus for integrated research strategies.

    Science.gov (United States)

    Hughes, Claude; Waters, Michael; Allen, David; Obasanjo, Iyabo

    2013-09-30

    Given that toxicology studies the potential adverse effects of environmental exposures on various forms of life and that clinical toxicology typically focuses on human health effects, what can and should the relatively new term of "translational toxicology" be taken to mean? Our assertion is that the core concept of translational toxicology must incorporate existing principles of toxicology and epidemiology, but be driven by the aim of developing safe and effective interventions beyond simple reduction or avoidance of exposure to prevent, mitigate or reverse adverse human health effects of exposures.The field of toxicology has now reached a point where advances in multiple areas of biomedical research and information technologies empower us to make fundamental transitions in directly impacting human health. Translational toxicology must encompass four action elements as follows: 1) Assessing human exposures in critical windows across the lifespan; 2) Defining modes of action and relevance of data from animal models; 3) Use of mathematical models to develop plausible predictions as the basis for: 4) Protective and restorative human health interventions. The discussion focuses on the critical window of in-utero development. Exposure assessment, basic toxicology and development of certain categories of mathematical models are not new areas of research; however overtly integrating these in order to conceive, assess and validate effective interventions to mitigate or reverse adverse effects of environmental exposures is our novel opportunity. This is what we should do in translational toxicology so that we have a portfolio of interventional options to improve human health that include both minimizing exposures and specific preventative/restorative/mitigative therapeutics.

  12. Summary of the working group on high current transport and final focus lenses

    International Nuclear Information System (INIS)

    Garren, A.A.

    1978-09-01

    The group reviewed recent work, and then addressed itself to relating the current understanding of relevant beam transport effects to the four reference concepts. In addition there was discussion on plans for future experimental and theoretical work. Discussions covered the following topics: (1) Transverse instabilities on intense beams through periodic focusing systems, (2) evaluation and correction of chromatic aberrations in the final beam transport lines, (3) evaluation and correction of geometric aberrations due to quadrupole fringe fields, and (4) ion focusing by electrons

  13. NASA Iced Aerodynamics and Controls Current Research

    Science.gov (United States)

    Addy, Gene

    2009-01-01

    This slide presentation reviews the state of current research in the area of aerodynamics and aircraft control with ice conditions by the Aviation Safety Program, part of the Integrated Resilient Aircraft Controls Project (IRAC). Included in the presentation is a overview of the modeling efforts. The objective of the modeling is to develop experimental and computational methods to model and predict aircraft response during adverse flight conditions, including icing. The Aircraft icing modeling efforts includes the Ice-Contaminated Aerodynamics Modeling, which examines the effects of ice contamination on aircraft aerodynamics, and CFD modeling of ice-contaminated aircraft aerodynamics, and Advanced Ice Accretion Process Modeling which examines the physics of ice accretion, and works on computational modeling of ice accretions. The IRAC testbed, a Generic Transport Model (GTM) and its use in the investigation of the effects of icing on its aerodynamics is also reviewed. This has led to a more thorough understanding and models, both theoretical and empirical of icing physics and ice accretion for airframes, advanced 3D ice accretion prediction codes, CFD methods for iced aerodynamics and better understanding of aircraft iced aerodynamics and its effects on control surface effectiveness.

  14. Psychological Therapies for Auditory Hallucinations (Voices): Current Status and Key Directions for Future Research

    NARCIS (Netherlands)

    Thomas, N.; Hayward, M.; Peters, E; van der Gaag, M.; Bentall, R.P.; Jenner, J.; Strauss, C.; Sommer, I.E.; Johns, L.C.; Varese, F.; Gracia-Montes, J.M.; Waters, F.; Dodgson, G.; McCarthy-Jones, S.

    2014-01-01

    This report from the International Consortium on Hallucinations Research considers the current status and future directions in research on psychological therapies targeting auditory hallucinations (hearing voices). Therapy approaches have evolved from behavioral and coping-focused interventions,

  15. LIS Practitioner-focused Research Trends Toward Open Access Journals, Academic-focused Research Toward Traditional Journals

    Directory of Open Access Journals (Sweden)

    Richard Hayman

    2018-03-01

    with academic-student collaborations (21.5%, practitioner librarian collaborations (15.5%, and librarian-academic collaborations (13.2%. Conclusion – LIS practitioner-focused research tends to appear more often in open access journals, while academic-focused researcher tends to appear more often in non-OA journals. These trends also appear in research collaborations, with co-authored works involving librarians appearing more often in OA journals, and collaborations that include academics more likely to appear in non-OA journals.

  16. Current sheath curvature correlation with the neon soft x-ray emission from plasma focus device

    International Nuclear Information System (INIS)

    Zhang, T; Lin, X; Chandra, K A; Tan, T L; Springham, S V; Patran, A; Lee, P; Lee, S; Rawat, R S

    2005-01-01

    The insulator sleeve length is one of the major parameters that can severely affect the neon soft x-ray yield from a plasma focus. The effect of the insulation sleeve length on various characteristic timings of plasma focus discharges and hence the soft x-ray emission characteristics has been investigated using a resistive divider. The pinhole images and laser shadowgraphy are used to explain the observed variation in the average soft x-ray yield (measured using a diode x-ray spectrometer) with variation of the insulator sleeve length. We have found that for a neon filled plasma focus device the change in insulator sleeve length changes the current sheath curvature angle and thus the length of the focused plasma column. The optimized current sheath curvature angle is found to be between 39 0 and 41 0 , at the specific axial position of 6.2-9.3 cm from the cathode support plate, for our 3.3 kJ plasma focus device. A strong dependence of the neon soft x-ray yield on the current sheath curvature angle has thus been reported

  17. A Focus Group Study of Child Nutrition Professionals' Attitudes about Food Allergies and Current Training Practices

    Science.gov (United States)

    Lee, Yee Ming; Kwon, Junehee; Sauer, Kevin

    2014-01-01

    Purpose/Objectives: The purpose of this study was to explore child nutrition professionals' (CNPs) attitudes about food allergies, current practices of food allergy training, and operational issues related to food allergy training in school foodservice operations. Methods: Three focus groups were conducted with 21 CNPs with managerial…

  18. Current trends in free software research

    OpenAIRE

    Navarro Bosch, Ramon; Vila Marta, Sebastià

    2009-01-01

    This report analyzes how scientific research is studying free software. We find which research is being done on free software by looking into scientific journals and conferences publications. The data thus obtained is analized and the most salient trends related to free software discovered. We also reviewed the main works published in each free software research area.

  19. Current status of the world's research reactors

    International Nuclear Information System (INIS)

    Dodd, B.

    1999-01-01

    Data from the IAEA's Research Reactor Database (RRDB) provides information with respect to the status of the world's research reactors. Some summary data are given. Recent initiatives by the IAEA regarding communications and information flow with respect to research reactors are discussed. Future plans and perspectives are also introduced. (author)

  20. Current frontiers and future directions of telecoupling research

    Science.gov (United States)

    Liu, J.

    2016-12-01

    The world has been increasingly interconnected over long distances though processes such as international trade, migration, telecommunication, and disease spread. However, previous studies often focused on socioeconomic or environmental issues of distant processes. While these studies have generated useful information for individual disciplines, integrating socioeconomic and environmental information is essential for holistic understanding of complex global challenges and unbiased decision making to address the challenges. To advance integrated research, the framework of telecoupling (socioeconomic and environmental interactions over distances) has been developed to explicitly address both socioeconomic and environmental issues simultaneously. Although the framework is relatively new, it has already been applied to tackle a variety of globally important issues, such as food security, water resources, energy sustainability, land use, international trade (e.g., food, forest products, energy, wildlife, industrial products), species invasion, investment, ecosystem services, conservation, information dissemination, and tourism. These applications have identified many important research gaps (e.g. spillover systems) and hidden linkages (e.g. feedbacks) among distant areas of the world with profound implications for sustainable development, ecosystem health, and human well-being. While working with telecoupling presents more challenges than focusing only on disciplinary issues, support from funding agencies has helped accelerate research on telecoupling and more efforts are being aimed at framework quantification and operationalization. The presenter will provide an overview of the current frontiers, discuss future research directions, and highlight emerging opportunities and challenges in telecoupling research and governance.

  1. Design of high-energy high-current linac with focusing by superconducting solenoids

    Energy Technology Data Exchange (ETDEWEB)

    Batskikh, G.I.; Belugin, V.M.; Bondarev, B.I. [Moscow Radiotechnical Institute (Russian Federation)] [and others

    1995-10-01

    The advancement of MRTI design for 1.5 GeV and 250 mA ion CW linac was presented in a previous report. In this new linac version all the way from input to output the ions are focused by magnetic fields of superconducting solenoids. The ion limit current is far beyond the needed value. The linac focusing channel offers major advantages over the more conventional ones. The acceptance is 1.7 times as large for such focusing channel as for quadrupole one. Concurrently, a random perturbation sensitivity for such channel is one order of magnitude smaller than in quadrupole channel. These focusing channel features allow to decrease beam matched radius and increase a linac radiation purity without aperture growth. {open_quotes}Regotron{close_quotes} is used as high power generator in linac main part. But D&W cavities need not be divided into sections connected by RF-bridges which denuded them of high coupling factor.

  2. Current status of nuclear physics research

    International Nuclear Information System (INIS)

    Bertulani, Carlos A.; Hussein, Mahir S.

    2015-01-01

    In this review, we discuss the current status of research in nuclear physics which is being carried out in different centers in the world. For this purpose, we supply a short account of the development in the area which evolved over the last nine decades, since the discovery of the neutron. The evolution of the physics of the atomic nucleus went through many stages as more data became available. We briefly discuss models introduced to discern the physics behind the experimental discoveries, such as the shell model, the collective model, the statistical model, the interacting boson model, etc., some of these models may be seemingly in conflict with each other, but this was shown to be only apparent. The richness of the ideas and abundance of theoretical models attests to the important fact that the nucleus is a really singular system in the sense that it evolves from two-body bound states such as the deuteron, to few-body bound states, such as 4 He, 7 Li, 9 Be, etc. and up the ladder to heavier bound nuclei containing up to more than 200 nucleons. Clearly, statistical mechanics, usually employed in systems with very large number of particles, would seemingly not work for such finite systems as the nuclei, neither do other theories which are applicable to condensed matter. The richness of nuclear physics stems from these restrictions. New theories and models are presently being developed. Theories of the structure and reactions of neutron-rich and proton-rich nuclei, called exotic nuclei, halo nuclei, or Borromean nuclei, deal with the wealth of experimental data that became available in the last 35 years. Furthermore, nuclear astrophysics and stellar and Big Bang nucleosynthesis have become a more mature subject. Due to limited space, this review only covers a few selected topics, mainly those with which the authors have worked on. Our aimed potential readers of this review are nuclear physicists and physicists in other areas, as well as graduate students interested

  3. Current status of nuclear physics research

    Energy Technology Data Exchange (ETDEWEB)

    Bertulani, Carlos A. [Department of Physics and Astronomy, Texas A and M University-Commerce (United States); Hussein, Mahir S., E-mail: hussein@if.usp.br [Instituto Tecnologico de Aeronautica (ITA), Sao Jose dos Campos, SP (Brazil). Dept. de Fisica

    2015-12-15

    In this review, we discuss the current status of research in nuclear physics which is being carried out in different centers in the world. For this purpose, we supply a short account of the development in the area which evolved over the last nine decades, since the discovery of the neutron. The evolution of the physics of the atomic nucleus went through many stages as more data became available. We briefly discuss models introduced to discern the physics behind the experimental discoveries, such as the shell model, the collective model, the statistical model, the interacting boson model, etc., some of these models may be seemingly in conflict with each other, but this was shown to be only apparent. The richness of the ideas and abundance of theoretical models attests to the important fact that the nucleus is a really singular system in the sense that it evolves from two-body bound states such as the deuteron, to few-body bound states, such as {sup 4}He, {sup 7}Li, {sup 9}Be, etc. and up the ladder to heavier bound nuclei containing up to more than 200 nucleons. Clearly, statistical mechanics, usually employed in systems with very large number of particles, would seemingly not work for such finite systems as the nuclei, neither do other theories which are applicable to condensed matter. The richness of nuclear physics stems from these restrictions. New theories and models are presently being developed. Theories of the structure and reactions of neutron-rich and proton-rich nuclei, called exotic nuclei, halo nuclei, or Borromean nuclei, deal with the wealth of experimental data that became available in the last 35 years. Furthermore, nuclear astrophysics and stellar and Big Bang nucleosynthesis have become a more mature subject. Due to limited space, this review only covers a few selected topics, mainly those with which the authors have worked on. Our aimed potential readers of this review are nuclear physicists and physicists in other areas, as well as graduate

  4. Navy Telemedicine: Current Research and Future Directions

    National Research Council Canada - National Science Library

    Reed, Cheryl

    2002-01-01

    .... An assessment of Navy telemedicine as a complex healthcare support system is needed to demonstrate how current practices, training, equipment, and expenditures measure up to the emerging needs of the Fleet...

  5. Picky eating : the current state of research

    NARCIS (Netherlands)

    Cano, S. Cardona; Hoek, Hans W.; Bryant-Waugh, Rachel

    2015-01-01

    Purpose of review In this review, an overview of literature on picky eating is given, with the focus on recently published studies. Recent findings Papers on picky eating published over the past 2 years broadly covered three themes: characterization of picky eating; factors contributing to the

  6. Neuroscience research in Africa: Current status

    OpenAIRE

    Abd-Allah, Foad; Kissani, Najib; William, Anthony; Oraby, Mohammed Ibrahim; Moustafa, Ramez Reda; Shaker, Ehab; El-Tamawy, Mohamed Soliman; Shakir, Raad

    2015-01-01

    There are limited data on the contribution of the African continent to neuroscience research and publications. This review aims to provide a clear view on the state of neuroscience research among African countries, and to compare neuroscience research within the 52 African countries. A literature review search was conducted for all published articles by African authors in both local and international journals using Medline and other primary databases. Neuroscience represents 9.1% of the total...

  7. Marine Radioecology. Current Research and Future Scope

    International Nuclear Information System (INIS)

    1967-03-01

    This report consists of answers submitted by various laboratory directors or individual investigators who responded to an International Atomic Energy Agency questionnaire concerning their present research programme, future scope of that programme, the investigators' ideas and opinions on marine radioecology research. Information on the possibility of co-operation with other laboratories is also included

  8. Neuroimaging for psychotherapy research: current trends.

    Science.gov (United States)

    Weingarten, Carol P; Strauman, Timothy J

    2015-01-01

    This article reviews neuroimaging studies that inform psychotherapy research. An introduction to neuroimaging methods is provided as background for the increasingly sophisticated breadth of methods and findings appearing in psychotherapy research. We compiled and assessed a comprehensive list of neuroimaging studies of psychotherapy outcome, along with selected examples of other types of studies that also are relevant to psychotherapy research. We emphasized magnetic resonance imaging (MRI) since it is the dominant neuroimaging modality in psychological research. We summarize findings from neuroimaging studies of psychotherapy outcome, including treatment for depression, obsessive compulsive disorder (OCD), and schizophrenia. The increasing use of neuroimaging methods in the study of psychotherapy continues to refine our understanding of both outcome and process. We suggest possible directions for future neuroimaging studies in psychotherapy research.

  9. Juvenile fibromyalgia: current status of research and future developments

    Science.gov (United States)

    Kashikar-Zuck, Susmita; Ting, Tracy V.

    2015-01-01

    Juvenile-onset fibromyalgia (JFM) is a poorly understood chronic pain condition most commonly affecting adolescent girls. The condition is characterized by widespread musculoskeletal pain and other associated symptoms, including fatigue, nonrestorative sleep, headaches, irritable bowel symptoms, dysautonomia and mood disorders such as anxiety and/or depression. In the past few years, there has been a greater focus on understanding JFM in adolescents. Research studies have provided insight into the clinical characteristics of this condition and its effect on both short-term and long-term psychosocial and physical functioning. The importance of early and effective intervention is being recognized, as research has shown that symptoms of JFM tend to persist and do not resolve over time as was previously believed. Efforts to improve treatments for JFM are underway, and new evidence strongly points to the potential benefits of cognitive–behavioural therapy on improving mood and daily functioning. Research into pharmacotherapy and other nonpharmacological options is in progress. Advancements in the understanding of adult fibromyalgia have paved the way for future studies on diagnosis, assessment and management of JFM. This Review focuses on our current knowledge of the condition, provides an update of the latest research advances, and highlights areas for further study. PMID:24275966

  10. How to conduct focus groups: researching group priorities through discussion.

    Science.gov (United States)

    1992-01-01

    Focus groups serve to uncover priorities and beliefs of a target group, but health project designers do not always take the time to seek this information beforehand. Focus groups also allow various local subgroups to communicate their concerns before the project starts. Focus groups can also breed ideas and dialogue that individual interviews cannot and they provide baseline information so managers can determine if attitudes or priorities have resulted from the project. Diverse people have different beliefs, e.g., women who have young children view oral rehydration therapy differently from women with no children. Project designers can use these basic differences to arrive at some conclusions about general attitudes. Focus group facilitators should have a discussion outline to help keep the group on the topic of concern. They should limit sessions to 60-90 minutes. Each focus groups should include 8-10 people. It is important to have members of various community subgroups in each group. Yet group designers should be careful not to include within the same group, those who may intimidate other people in the group, e.g., in situations where farmers depend on middlemen, farmers may not be open if middlemen are also in the focus group. Facilitators should launch each session with an attempt to encourage the members to be open and to feel comfortable. For example, in Malawi, a facilitator leads her focus group discussions with songs. Stories are another icebreaker. It is important that all focus groups centering around a certain project discuss the same topics. Facilitators need to stress to the group that all discussions are to be kept confidential. The designers should also carefully word the questions so that facilitators will not impart their bias. Facilitators should not direct the group to certain conclusions, but instead keep the discussions focused.

  11. Electromagnetic particle in cell modeling of the plasma focus: Current sheath formation and lift off

    International Nuclear Information System (INIS)

    Seng, Y. S.; Lee, P.; Rawat, R. S.

    2014-01-01

    The shaping and formation of the current sheath takes place in the breakdown phase of a plasma focus device and critically controls the device performance. Electrostatic particle in cell codes, with magnetic effects ignored, have been used to model the breakdown phase. This Letter reports the successful development and implementation of an electromagnetic particle in cell (EMPIC) code, including magnetic effects self-consistently, to simulate the breakdown phase; from the ionization, localization and gliding discharge along the insulator to the time instant of current sheath lift off. The magnetic field was found to be appreciable from the time the current sheath came into contact with the anode with increased local current, initiating the voltage breakdown of the device as a result

  12. The Impact of Natural Disasters on Youth: A Focus on Emerging Research beyond Internalizing Disorders.

    Science.gov (United States)

    Self-Brown, Shannon; Lai, Betty; Patterson, Alexandria; Glasheen, Theresa

    2017-08-01

    This paper reviews youth outcomes following exposure to natural disaster, with a focus on three relatively understudied outcomes: externalizing behavior problems, physical health, and posttraumatic growth. Recent, high-impact studies focusing on each outcome are summarized. Studies highlighted in this review utilize innovative and comprehensive approaches to improve our current understanding of youth broad-based physical and mental health outcomes beyond PTSD. The review concludes with recommendations to advance the field of youth disaster research by exploring how disasters may impact children across multiple domains, as well as using cutting edge ecobiological approaches and advanced modeling strategies to better understand how youth adjust and thrive following natural disaster.

  13. Loyalty Programmes : Current Knowledge and Research Directions

    NARCIS (Netherlands)

    Dorotic, Matilda; Bijmolt, Tammo H. A.; Verhoef, Peter C.

    Loyalty programmes (LPs) have increased in number and popularity, but their effects on customer behaviour remain equivocal, due to a lack of understanding of the drivers of LP effectiveness and insufficient generalizable conclusions across prior studies. This paper synthesizes current knowledge

  14. High current betatron research at the University of New Mexico

    International Nuclear Information System (INIS)

    Humphries, S. Jr.; Len, L.K.

    1987-01-01

    Betatrons are among the simplest of high energy accelerators. Their circuit is equivalent to a step-up transformer; the electron beam forms a multi-turn secondary winding. Circulation of the beam around the flux core allows generation of high energy electrons with relatively small core mass. As with any transformer, a betatron is energy inefficient at low beam current; the energy balance is dominated by core losses. This fact has prompted a continuing investigation of high current betatrons as efficient, compact sources of beta and gamma radiation. A program has been supported at the University of New Mexico by the Office of Naval Research to study the physics of high current electron beams in circular accelerators and to develop practical technology for high power betatrons. Fabrication and assembly of the main ring was completed in January of this year. In contrast to other recent high current betatron experiments the UNM device utilizes a periodic focusing system to contain high current beams during the low energy phase of the acceleration cycle. The reversing cusp fields generated by alternating polarity solenoidal lenses cancel beam drift motions induced by machine errors. In consequence, they have found that the cusp geometry has had significantly better stability properties than a monodirectional toroidal field. In comparison to other minimum-Β geometries such as the Stelllatron cusps have open field lines which facilitate beam injection and neutralization

  15. Current Challenges and Achievements in Maternal Immunization Research

    Directory of Open Access Journals (Sweden)

    Flor M. Munoz

    2018-03-01

    Full Text Available Maternal immunization has the potential to significantly improve maternal and child health worldwide by reducing maternal and infant morbidity and mortality associated with disease caused by pathogens that are particularly relevant in the perinatal period and in early life, and for which no alternative effective preventive strategies exist. Research on all aspects related to vaccines for administration during pregnancy is ongoing with support of multiple stakeholders and global participation. Substantial progress has been made, and the availability of new vaccines licensed exclusively for use in pregnant women to protect their infants has become an achievable goal. This review provides an update of the current challenges and achievements in maternal immunization research, focusing on recent milestones that advance the field and the prospects to make maternal immunization a feasible and accessible strategy to improve global health.

  16. EPA Toxicologists Focus Innovative Research on PFAS Compounds

    Science.gov (United States)

    EPA researchers have partnered with researchers at the National Toxicology Program to develop a tiered testing approach to quickly generate toxicity and kinetic information for approximately 75 PFAS compounds.

  17. Review of current researches on internet addiction

    International Nuclear Information System (INIS)

    Hu Yanni; Tian Mei; Zhang Hong

    2012-01-01

    Internet addiction (IA) is a mental illness emerged in recent years with increasing use of computer and internet. The serious consequences such as mental and physical illness and social function impairment caused by IA have attracted extensive attention of the whole society. IA affects human beings at a high prevalence all over the world which has highlighted the importance of prevention and treatment of IA. Although there is still debate about definition of IA, increasing evidences including the result from genetic research,neurobiology study and clinical manifestation show that IA may share the same mechanisms with substance addiction, and be probably classified as behavioral addiction which is represented by pathological gambling. However, since the study on IA is yet on the initial stage and neuro biological research on IA is still limited, more reliable investigations especially neuro biological research remains uppermost in this area. (authors)

  18. Soy Saponins: Current Research and Future Goals

    Science.gov (United States)

    Saponins are a biologically active class of triterpenoid phytochemicals found in soybeans at concentrations similar to those of the isoflavones, and the role they may play in nutrition and health is not well understood. Research the functionality of these compounds in animals and humans has been ha...

  19. Overcoming the current deadlock in antibiotic research.

    Science.gov (United States)

    Schäberle, Till F; Hack, Ingrid M

    2014-04-01

    Antibiotic-resistant bacteria are on the rise, making it harder to treat bacterial infections. The situation is aggravated by the shrinking of the antibiotic development pipeline. To finance urgently needed incentives for antibiotic research, creative financing solutions are needed. Public-private partnerships (PPPs) are a successful model for moving forward. Copyright © 2013 Elsevier Ltd. All rights reserved.

  20. The Current State of Research on Motivation

    Science.gov (United States)

    Geering, Adrian D.

    The literature on motivation theory is growing rapidly due to increased interest by leaders in all types of organizations in social-psychology variables such as internal commitment and motivation to work. This paper presents an overview of motivational research, covering early behavior theories such as scientific management and human relations,…

  1. Researches on regenerative medicine-current state

    Directory of Open Access Journals (Sweden)

    WANG Zheng-guo

    2012-11-01

    Full Text Available 【Abstract】 Since 1980s, the rapid development of tissue engineering and stem cell research has pushed re-generative medicine to a new fastigium, and regenerative medicine has become a noticeable research field in the international biology and medicine. In China, about 100 million patients need repair and regeneration treatment every year, while the number is much larger in the world. Regenerative medicine could provide effective salvation for these patients. Both Chinese Academy of Sciences and Chinese Academy of Engineering have made roadmaps of 2010-2050 and 2011-2030 for regenerative medicine. The final goal of the two roadmaps is to make China go up to leading position in most research aspects of regenerative medicine. In accord with this strategy, the government and some enterprises have invested 3-5 billion RMB (0.5-0.8 billion USD for the research on regenerative medicine. In order to push the translation of regenerative medicine forward—from bench to bedside, a strategic alliance has been established, and it includes 27 top-level research institutes, medical institutes, colleges, universities and enterprises in the field of stem cell and regeneration medicine. Recently the journal, Science, has published a special issue—Regenerative Medi-cine in China, consisting of 35 papers dealing with stem cell and regeneration, tissue engineering and regeneration, trauma and regeneration and bases for tissue repair and regenerative medicine. It is predicated that a greater breakthrough in theory and practice of regenerative medicine will be achieved in the near future (20 to 30 years. Key words: Regenerative medicine; Tissue engineering; Stem cells; Wound healing

  2. US computer research networks: Current and future

    Science.gov (United States)

    Kratochvil, D.; Sood, D.; Verostko, A.

    1989-01-01

    During the last decade, NASA LeRC's Communication Program has conducted a series of telecommunications forecasting studies to project trends and requirements and to identify critical telecommunications technologies that must be developed to meet future requirements. The Government Networks Division of Contel Federal Systems has assisted NASA in these studies, and the current study builds upon these earlier efforts. The current major thrust of the NASA Communications Program is aimed at developing the high risk, advanced, communications satellite and terminal technologies required to significantly increase the capacity of future communications systems. Also, major new technological, economic, and social-political events and trends are now shaping the communications industry of the future. Therefore, a re-examination of future telecommunications needs and requirements is necessary to enable NASA to make management decisions in its Communications Program and to ensure the proper technologies and systems are addressed. This study, through a series of Task Orders, is helping NASA define the likely communication service needs and requirements of the future and thereby ensuring that the most appropriate technology developments are pursued.

  3. Current clinical research in orthodontics: a perspective.

    Science.gov (United States)

    Baumrind, Sheldon

    2006-10-01

    This essay explores briefly the approach of the Craniofacial Research Instrumentation Laboratory to the systematic and rigorous investigation of the usual outcome of orthodontic treatment in the practices of experienced clinicians. CRIL's goal is to produce a shareable electronic database of reliable, valid, and representative data on clinical practice as an aid in the production of an improved environment for truly evidence-based orthodontic treatment.

  4. Canada's International Education Strategy: Focus on Scholarships. CBIE Research

    Science.gov (United States)

    Embleton, Sheila

    2011-01-01

    Based on a survey of approximately 40 professionals involved in various disciplines associated with international education across Canada, this study examines Canada's (federal, provincial, and territorial government) offering of scholarships to international students. Focused at the university level, the study elaborates on relevant international…

  5. Report Focuses on Integrity and Accessibility of Research Data

    Science.gov (United States)

    Showstack, Randy

    2009-08-01

    Rapid advances in digital technologies and enormous increases in the amount of data generated by research projects and a variety of instruments and sensors are providing new research opportunities. These advances, however, also can present challenges for ensuring that digital technologies are not used inappropriately and for managing an increasing amount of data, according to a new report issued by the U.S. National Academy of Sciences, National Academy of Engineering, and Institute of Medicine on 22 July. The new report, entitled “Ensuring the integrity, accessibility, and stewardship of research data in the digital age,” provides general principles and recommendations about the handling of research data. The report notes that the development of policies, standards, and infrastructure “is a critically important task” that will require a sustained effort from stakeholders including researchers, research institutions and sponsors, and professional societies and journals.

  6. Advances in research methods for information systems research data mining, data envelopment analysis, value focused thinking

    CERN Document Server

    Osei-Bryson, Kweku-Muata

    2013-01-01

    Advances in social science research methodologies and data analytic methods are changing the way research in information systems is conducted. New developments in statistical software technologies for data mining (DM) such as regression splines or decision tree induction can be used to assist researchers in systematic post-positivist theory testing and development. Established management science techniques like data envelopment analysis (DEA), and value focused thinking (VFT) can be used in combination with traditional statistical analysis and data mining techniques to more effectively explore

  7. Intelligent multimedia surveillance current trends and research

    CERN Document Server

    Atrey, Pradeep K; Cavallaro, Andrea

    2013-01-01

    Intelligent multimedia surveillance concerns the analysis of multiple sensing inputs including video and audio streams, radio-frequency identification (RFID), and depth data. These data are processed for the automated detection and tracking of people, vehicles, and other objects. The goal is to locate moving targets, to understand their behavior, and to detect suspicious or abnormal activities for crime prevention. Despite its benefits, there is societal apprehension regarding the use of such technology, so an important challenge in this research area is to balance public safety and privacy.

  8. The current status of Kartini research reactor

    Energy Technology Data Exchange (ETDEWEB)

    Tjiptono, Tri Wulan; Syarip,

    1998-10-01

    The Kartini reactor reached the first criticality on January 25, 1979. In the first three years, the reactor power is limited up to 50 kW thermal power and on July 1, 1982 has been increased to 100 kW. It has been used as experiments facility by researcher of Atomic Energy National Agency and students of the Universities. Three beam tubes used as experiments facilities, the first, is used as a neutron source for H{sub 2}O-Natural Uranium Subcritical Assembly, the second, is developed for neutron radiography facility and the third, is used for gamma radiography facility. The other facilities are rotary rack and two pneumatic transfer systems, one for delayed neutron counting system and the other for the new Neutron Activation Analysis (NAA) facility. The rotary rack used for isotope production for NAA purpose (for long time irradiation), the delayed neutron counting system used for analysis the Uranium contents of the ores and the new NAA is provided for short live elements analysis. In the last three years the Reactor Division has a joint use program with the Nuclear Component and Engineering Center in research reactor instrumentation and control development. (author)

  9. Airbreathing Hypersonic Systems Focus at NASA Langley Research Center

    Science.gov (United States)

    Hunt, James L.; Rausch, Vincent L.

    1998-01-01

    This paper presents the status of the airbreathing hypersonic airplane and space-access vehicle design matrix, reflects on the synergies and issues, and indicates the thrust of the effort to resolve the design matrix and to focus/advance systems technology maturation. Priority is given to the design of the vision operational vehicles followed by flow-down requirements to flight demonstrator vehicles and their design for eventual consideration in the Future-X Program.

  10. Current status of surrogacy in Japan and uterine transplantation research.

    Science.gov (United States)

    Kisu, Iori; Banno, Kouji; Mihara, Makoto; Iida, Takuya; Yoshimura, Yasunori

    2011-10-01

    Recent advances in assisted reproductive technology (ART) have made it possible to circumvent many causes of male and female infertility. The right to have a child by ART has been respected for infertile couples. However, there are currently no legal regulations concerning ART in Japan, and this has resulted in social and ethical problems. Surrogacy involves particularly complex medical, ethical, social, and legal issues, and is frequently focused on as a major social concern. Uterine transplantation (UTx) is a potential alternative for young women with uterine factor infertility due to hysterectomy for treatment of a malignant uterine tumor or massive blood loss after delivery, or because of a congenital disease such as Mayer-Rokitansky-Küster syndrome. UTx has been examined in experimental animals as a basis for establishment of fecundity for young women with uterine factor infertility. In this review, we focus on surrogacy in Japan and UTx research, and discuss the current status and concerns in this field. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  11. Current state of nuclear fusion research

    International Nuclear Information System (INIS)

    Naraghi, M.

    1985-01-01

    During the past quarter century, plasma physics and nuclear fusion research have gone through impressive development. Tokamak, is realized to be the number one candidate for nuclear fusion reactor. Two large experiments, one called Joint European Torus (JET) at Culham, England, and the other JT-60 project in Japan have been completed and have reported preliminary results. In JET an average electron density of 4x10 13 pcls/ cm 3 , ion temperatures of 3Kev and energy confinement of 0.8 sec have been achieved. However, the Zeff has been even equal to 10 which unfortunately is a source of plasma energy loss. JT-60 has not offered any appreciable results yet, however, the objectives and initial tests promise long pulse duration, with very high ion and plasma densities. Both experiments have promised to achieve conditions approaching those needed in a fusion reactor. Other important experiments will be discussed and the role of third world countries will be emphasized. (Author)

  12. Nanofluid Technology: Current Status and Future Research

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Stephen U.-S. [Argonne National Lab. (ANL), Argonne, IL (United States). Energy Technology Division

    1998-10-20

    Downscaling or miniaturization has been a recent major trend in modern science and technology. Engineers now fabricate microscale devices such as microchannel heat exchangers, and micropumps that are the size of dust specks. Further major advances would be obtained if the coolant flowing in the microchannels were to contain nanoscale particles to enhance heat transfer. Nanofluid technology will thus be an emerging and exciting technology of the 21st century. This paper gives a brief history of the Advanced Fluids Program at Argonne National Laboratory (ANL), discusses the concept of nanofluids, and provides an overview of the R&D program at ANL on the production, property characterization, and performance of nanofluids. It also describes examples of potential applications and benefits of nanofluids. Finally, future research on the fundamentals and applications of nanofluids is addressed.

  13. Intuitive Physics: Current Research and Controversies.

    Science.gov (United States)

    Kubricht, James R; Holyoak, Keith J; Lu, Hongjing

    2017-10-01

    Early research in the field of intuitive physics provided extensive evidence that humans succumb to common misconceptions and biases when predicting, judging, and explaining activity in the physical world. Recent work has demonstrated that, across a diverse range of situations, some biases can be explained by the application of normative physical principles to noisy perceptual inputs. However, it remains unclear how knowledge of physical principles is learned, represented, and applied to novel situations. In this review we discuss theoretical advances from heuristic models to knowledge-based, probabilistic simulation models, as well as recent deep-learning models. We also consider how recent work may be reconciled with earlier findings that favored heuristic models. Copyright © 2017 Elsevier Ltd. All rights reserved.

  14. Advanced radiation chemistry research: Current status

    International Nuclear Information System (INIS)

    1995-10-01

    Radiation chemistry is a branch of chemistry that studies chemical transformations in materials exposed to high-energy radiations. It is based on the use of ionizing radiation as the initiator or catalyst in chemical reactions. The most significant advantage of radiation chemistry lies in its ability to be used in the production and study of almost any reactive atomic and molecular species playing a part in chemical reaction, synthesis, industrial processes, or in biological systems. Over the the last few years a number of meetings have taken place, under the auspices of the IAEA, in order to evaluate recent developments in radiation chemistry as well as the trends indicated by the results obtained. Radiation chemists from different countries have participated at these meetings. The present publication, a companion to the previous publication - New Trends and Development in Radiation Chemistry, IAEA-TECDOC-527 (1989) - includes some of the important contributions presented at these meetings. It is hoped that it will provide a useful overview of current activities and of emerging trends in this field, thus promoting better understanding of potential contributions of radiation chemistry to other fields of knowledge as well as to practical applications in industry, medicine and agriculture. Refs, figs and tabs

  15. Advanced radiation chemistry research: Current status

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-10-01

    Radiation chemistry is a branch of chemistry that studies chemical transformations in materials exposed to high-energy radiations. It is based on the use of ionizing radiation as the initiator or catalyst in chemical reactions. The most significant advantage of radiation chemistry lies in its ability to be used in the production and study of almost any reactive atomic and molecular species playing a part in chemical reaction, synthesis, industrial processes, or in biological systems. Over the the last few years a number of meetings have taken place, under the auspices of the IAEA, in order to evaluate recent developments in radiation chemistry as well as the trends indicated by the results obtained. Radiation chemists from different countries have participated at these meetings. The present publication, a companion to the previous publication - New Trends and Development in Radiation Chemistry, IAEA-TECDOC-527 (1989) - includes some of the important contributions presented at these meetings. It is hoped that it will provide a useful overview of current activities and of emerging trends in this field, thus promoting better understanding of potential contributions of radiation chemistry to other fields of knowledge as well as to practical applications in industry, medicine and agriculture. Refs, figs and tabs.

  16. Flux-focusing eddy current probe and rotating probe method for flaw detection

    Science.gov (United States)

    Wincheski, Buzz A.; Fulton, James P.; Nath, Shridhar C.; Simpson, John W.; Namkung, Min

    1994-11-01

    A flux-focusing electromagnetic sensor which uses a ferromagnetic flux-focusing lens simplifies inspections and increases detectability of fatigue cracks about circular fasteners and other circular inhomogeneities in high conductivity material. The unique feature of the device is the ferrous shield isolating a high-turn pick-up coil from an excitation coil. The use of the magnetic shield is shown to produce a null voltage output across the receiving coil in the presence of an unflawed sample. A redistribution of the current flow in the sample caused by the presence of flaws, however, eliminates the shielding condition and a large output voltage is produced, yielding a clear unambiguous flaw signal. By rotating the probe in a path around a circular fastener such as a rivet while maintaining a constant distance between the probe and the center of a rivet, the signal due to current flow about the rivet can be held constant. Any further changes in the current distribution, such as due to a fatigue crack at the rivet joint, can be detected as an increase in the output voltage above that due to the flow about the rivet head.

  17. Measurement of electron- and ion beam energies and currents in a plasma focus discharge

    International Nuclear Information System (INIS)

    Yamamoto, Toshikazu; Kondoh, Yoshiomi; Shimoda, Katsuji; Hirano, Katsumi

    1982-01-01

    Measurements of energetic particle beams in a plsma focus with a Mather type device are presented. Rogowski coils are used for time-resolved measurement, and solid-state nuclear track detectors for time-integrated measurement of the beams. In the upstream direction with respect to the discharge current, only the electron beam with the maximum current of several kA was detected, which was approximately one percent of the discharge current. The electron energies of the beam were spread from 0.1 to 1 MeV. In the downstream direction, two successive emissions of ions were observed. The first emission had an extremely high energy of the order of some MeV and a low beam current of less than 10 A. The second emission, the main part of the ion beam, with energies of 100 - 800 keV, followed the first one with a time lag of several tens of nanoseconds, and the beam current reached several tens of amperes. (author)

  18. Current Rehabilitation Practices for Children with Cerebral Palsy: Focus and Gaps.

    Science.gov (United States)

    Anaby, Dana; Korner-Bitensky, Nicol; Steven, Emma; Tremblay, Stephanie; Snider, Laurie; Avery, Lisa; Law, Mary

    2017-02-01

    To describe the focus of therapy practices in occupational and physical therapy for school-aged children with cerebral palsy, and better understand whether it is congruent with recommended practices. A Canada-wide Web-based survey was completed by 62 occupational and 61 physical therapists to identify problems, assessments, and treatment interventions for two case-based scenarios. Data were coded using the International Classification of Functioning, Disability and Health (ICF) definitions for "body functions and structure," "activity and participation," and "environment." Physical therapists, in comparison to occupational therapists, were more likely to select interventions classed in the "body functions and structure" category (34-42% and 18-20%, respectively). Both professions focused on "activity and participation" (34-61%) when identifying problems, assessing, and intervening; attention, however, was mainly directed towards task-oriented activities such as activities of daily living and mobility. Participation in leisure or community-based activities received less attention (2-15%). The environment received limited attention for problems and assessments (4-25%), though it was an important focus of intervention (19-37%). While body functions and structure are well-addressed, other ICF elements, specifically participation, are poorly integrated into practice. The emerging focus on the environment in therapy intervention, by modifying the context rather than changing aspects of the child, is consistent with current approaches and evidence. Knowledge translation implementation initiatives are recommended to bridge identified gaps.

  19. Interview series focuses on IDRC-funded research on climate ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    In Conversation is a series of interviews and videos of research partners working on climate change adaptation projects in Africa, Asia, and Latin America and the Caribbean, funded through IDRC's Climate Change and Water program.

  20. Focus on CSIR research in pollution and waste: environmental health

    CSIR Research Space (South Africa)

    Godfrey, Linda K

    2007-08-01

    Full Text Available A healthy population is seen as an important precondition for economic growth and competitiveness. Research into environmental health is therefore concerned with understanding the exposure and magnitude of impact on humans from environmental hazards...

  1. Current state of molecular imaging research

    International Nuclear Information System (INIS)

    Grimm, J.; Wunder, A.

    2005-01-01

    The recent years have seen significant advances in both molecular biology, allowing the identification of genes and pathways related to disease, and imaging technologies that allow for improved spatial and temporal resolution, enhanced sensitivity, better depth penetration, improved image processing, and beneficial combinations of different imaging modalities. These advances have led to a paradigm shift in the scope of diagnostic imaging. The traditional role of radiological diagnostic imaging is to define gross anatomy and structure in order to detect pathological abnormalities. Available contrast agents are mostly non-specific and can be used to image physiological processes such as changes in blood volume, flow, and perfusion but not to demonstrate pathological alterations at molecular levels. However, alterations at the anatomical-morphological level are relatively late manifestations of underlying molecular changes. Using molecular probes or markers that bind specifically to molecular targets allows for the non-invasive visualization and quantitation of biological processes such as gene expression, apoptosis, or angiogenesis at the molecular level within intact living organisms. This rapidly evolving, multidisciplinary approach, referred to as molecular imaging, promises to enable early diagnosis, can provide improved classification of stage and severity of disease, an objective assessment of treatment efficacy, and a reliable prognosis. Furthermore, molecular imaging is an important tool for the evaluation of physiological and pathophysiological processes, and for the development of new therapies. This article comprises a review of current technologies of molecular imaging, describes the development of contrast agents and various imaging modalities, new applications in specific disease models, and potential future developments. (orig.)

  2. Dynamics of the plasma current sheath in plasma focus discharges in different gases

    Energy Technology Data Exchange (ETDEWEB)

    Vinogradov, V. P.; Krauz, V. I., E-mail: krauz-vi@nrcki.ru [National Research Center Kurchatov Institute (Russian Federation); Mokeev, A. N. [Project Center ITER (Russian Federation); Myalton, V. V.; Kharrasov, A. M. [National Research Center Kurchatov Institute (Russian Federation)

    2016-12-15

    The shape of the plasma current sheath (PCS) in the final stage of its radial compression, the dynamics of pinching, and the subsequent pinch decay in plasma focus (PF) discharges in different gases are studied using an improved multichannel system of electron-optical plasma photography and a newly elaborated synchronization system. The PCS structure in discharges in heavy gases (Ne, Ar) is found to differ significantly from that in discharges in hydrogen and deuterium. The influence of a heavy gas (Xe) additive to hydrogen and deuterium on the structure and compression dynamics of the PCS is investigated.

  3. Current research and development at the Nuclear Research Center Karlsruhe

    International Nuclear Information System (INIS)

    Kuesters, H.

    1982-01-01

    The Nuclear Research Center Karlsruhe (KfK) is funded to 90% by the Federal Republic of Germany and to 10% by the State of Baden-Wuerttemberg. Since its foundation in 1956 the main objective of the Center is research and development (R and D) in the aera of the nuclear technology and about 2/3 of the research capacity is now devoted to this field. Since 1960 a major activity of KfK is R and D work for the design of fast breeder reactors, including material research, physics, and safety investigations; a prototype of 300 MWe is under construction now in the lower Rhine Valley. For enrichment of 235 U fissile material KfK developed the separation nozzle process; its technical application is realized within an international contract between the Federal Republic of Germany and Brazil. Within the frame of the European Programme on fusion technology KfK develops and tests superconducting magnets for toroidal fusion systems; a smaller activity deals with research on inertial confinement fusion. A broad research programme is carried through for safety investigations of nuclear installations, especially for PWRs; this activity is supplemented by research and development in the field of nuclear materials' safeguards. Development of fast reactors has to initiate research for the reprocessing of spent fuel and waste disposal. In the pilot plant WAK spent fuel from LKWs is reprocessed; research especially tries e.g. to improve the PUREX-process by electrochemical means, vitrification of high active waste is another main activity. First studies are being performed now to clarify the necessary development for reprocessing fast reactor fuel. About 1/3 of the research capacity of KfK deals with fundamental research in nuclear physics, solid state physics, biology and studies on the impact of technology on environment. Promising new technologies as e.g. the replacement of gasoline by hydrogen cells as vehicle propulsion are investigated. (orig.)

  4. Risk of vicarious trauma in nursing research: a focused mapping review and synthesis.

    Science.gov (United States)

    Taylor, Julie; Bradbury-Jones, Caroline; Breckenridge, Jenna P; Jones, Christine; Herber, Oliver Rudolf

    2016-10-01

    To provide a snapshot of how vicarious trauma is considered within the published nursing research literature. Vicarious trauma (secondary traumatic stress) has been the focus of attention in nursing practice for many years. The most pertinent areas to invoke vicarious trauma in research have been suggested as abuse/violence and death/dying. What is not known is how researchers account for the risks of vicarious trauma in research. Focused mapping review and synthesis. Empirical studies meeting criteria for abuse/violence or death/dying in relevant Scopus ranked top nursing journals (n = 6) January 2009 to December 2014. Relevant papers were scrutinised for the extent to which researchers discussed the risk of vicarious trauma. Aspects of the studies were mapped systematically to a pre-defined template, allowing patterns and gaps in authors' reporting to be determined. These were synthesised into a coherent profile of current reporting practices and from this, a new conceptualisation seeking to anticipate and address the risk of vicarious trauma was developed. Two thousand five hundred and three papers were published during the review period, of which 104 met the inclusion criteria. Studies were distributed evenly by method (52 qualitative; 51 quantitative; one mixed methods) and by focus (54 abuse/violence; 50 death/dying). The majority of studies (98) were carried out in adult populations. Only two papers reported on vicarious trauma. The conceptualisation of vicarious trauma takes account of both sensitivity of the substantive data collected, and closeness of those involved with the research. This might assist researchers in designing ethical and protective research and foreground the importance of managing risks of vicarious trauma. Vicarious trauma is not well considered in research into clinically important topics. Our proposed framework allows for consideration of these so that precautionary measures can be put in place to minimise harm to staff. © 2016

  5. "Ganando Confianza": Research Focus Groups with Immigrant Mexican Mothers

    Science.gov (United States)

    Hausmann-Stabile, Carolina; Zayas, Luis H.; Runes, Sandra; Abenis-Cintron, Anna; Calzada, Esther

    2011-01-01

    Immigrant families with children with developmental disabilities must be served using culturally sensitive approaches to service and research to maximize treatment benefits. In an effort to better understand cultural issues relevant to the provision of parenting programs for immigrant Mexican mothers of children with developmental disabilities, we…

  6. A Research Focused on Improving Vocalisation Level on Violin Education

    Science.gov (United States)

    Parasiz, Gökalp

    2018-01-01

    The research aimed to improve vocalisation levels of music teacher's candidates on performance works for violin education moving from difficulties faced by prospective teachers. At the same time, it was aimed to provide new perspectives to violin educators. Study group was composed of six 3rd grade students studying violin education in a State…

  7. Focus Article: Replication in Second Language Writing Research

    Science.gov (United States)

    Porte, Graeme; Richards, Keith

    2012-01-01

    This paper discusses the meaning and range of replication in L2 research from both quantitative and qualitative perspectives. In the first half of the paper, it will be argued that key quantitative studies need to be replicated to have their robustness and generalizability tested and that this is a requirement of scientific inquiry. Such research…

  8. Faculty at Work: Focus on Research, Scholarship, and Service.

    Science.gov (United States)

    Blackburn, Robert T.; And Others

    1991-01-01

    A study compared selected personal and environmental motivational variables in college faculty with allocation of work effort to research, scholarship, and service. Faculty were from eight liberal arts and sciences departments in a range of institution types. For all institutional types, self-valuation motivators significantly accounted for the…

  9. Current Debates in Corporate Social Responsibility: An Agenda for Research

    Directory of Open Access Journals (Sweden)

    David Crowther

    2007-06-01

    Full Text Available Corporate Social Responsibility (CSR has a particular prominence at this point in time, featuring heavily in the discourses of both academe and business. The understanding of what is meant by CSR continues to evolve as a consensus is reached. Nevertheless some important debates continue – or are commencing – which need to be resolved. It is the purpose of this paper to highlight these as some of the current debates within the CSR community – and hence form a significant part of an agenda for research in the area. Specifically we focus upon three key areas for the management of business, namely setting standards for reporting, identifying and implementing sustainable practice, and the management of risk.

  10. Researchers focus attention on coastal response to climate change

    Science.gov (United States)

    Anderson, John; Rodriguez, Antonio; Fletcher, Charles; Fitzgerald, Duncan

    The world's population has been steadily migrating toward coastal cities, resulting in severe stress on coastal environments. But the most severe human impact on coastal regions may lie ahead as the rate of global sea-level rise accelerates and the impacts of global warming on coastal climates and oceanographic dynamics increase [Varekamp and Thomas, 1998; Hinrichsen, 1999; Goodwin et al., 2000]. Little is currently being done to forecast the impact of global climate change on coasts during the next century and beyond. Indeed, there are still many politicians, and even some scientists, who doubt that global change is a real threat to society.

  11. Refocusing International Astronomy Education Research Using a Cognitive Focus

    Science.gov (United States)

    Slater, Timothy F.; Slater, Stephanie J.

    2015-08-01

    For over 40 years, the international astronomy education community has given its attention to cataloging the substantial body of "misconceptions" in individual's thinking about astronomy, and to addressing the consequences of those misconceptions in the science classroom. Despite the tremendous amount of effort given to researching and disseminating information related to misconceptions, and the development of a theory of conceptual change to mitigate misconceptions, progress continues to be less than satisfying. An analysis of the literature and our own research has motivated the CAPER Center for Astronomy & Physics Education Research to advance a new model that allowing us to operate on students' astronomical learning difficulties in a more fruitful manner. Previously, much of the field's work binned erroneous student thinking into a single construct, and from that basis, curriculum developers and instructors addressed student misconceptions with a single instructional strategy. In contrast this model suggests that "misconceptions" are a mixture of at least four learning barriers: incorrect factual information, inappropriately applied mental algorithms (e.g., phenomenological primitives), insufficient cognitive structures (e.g., spatial reasoning), and affective/emotional difficulties. Each of these types of barriers should be addressed with an appropriately designed instructional strategy. Initial applications of this model to learning problems in astronomy and the space sciences have been fruitful, suggesting that an effort towards categorizing persistent learning difficulties in astronomy beyond the level of "misconceptions" may allow our community to craft tailored and more effective learning experiences for our students and the general public.

  12. Improving speech perception in noise with current focusing in cochlear implant users.

    Science.gov (United States)

    Srinivasan, Arthi G; Padilla, Monica; Shannon, Robert V; Landsberger, David M

    2013-05-01

    Cochlear implant (CI) users typically have excellent speech recognition in quiet but struggle with understanding speech in noise. It is thought that broad current spread from stimulating electrodes causes adjacent electrodes to activate overlapping populations of neurons which results in interactions across adjacent channels. Current focusing has been studied as a way to reduce spread of excitation, and therefore, reduce channel interactions. In particular, partial tripolar stimulation has been shown to reduce spread of excitation relative to monopolar stimulation. However, the crucial question is whether this benefit translates to improvements in speech perception. In this study, we compared speech perception in noise with experimental monopolar and partial tripolar speech processing strategies. The two strategies were matched in terms of number of active electrodes, microphone, filterbanks, stimulation rate and loudness (although both strategies used a lower stimulation rate than typical clinical strategies). The results of this study showed a significant improvement in speech perception in noise with partial tripolar stimulation. All subjects benefited from the current focused speech processing strategy. There was a mean improvement in speech recognition threshold of 2.7 dB in a digits in noise task and a mean improvement of 3 dB in a sentences in noise task with partial tripolar stimulation relative to monopolar stimulation. Although the experimental monopolar strategy was worse than the clinical, presumably due to different microphones, frequency allocations and stimulation rates, the experimental partial-tripolar strategy, which had the same changes, showed no acute deficit relative to the clinical. Copyright © 2013 Elsevier B.V. All rights reserved.

  13. Australian Aboriginal and Torres Strait Islander-focused primary healthcare social and emotional wellbeing research: a systematic review protocol.

    Science.gov (United States)

    Farnbach, Sara; Eades, Anne-Marie; Hackett, Maree Lisa

    2015-12-30

    Research with a focus on Aboriginal and Torres Strait Islander Australian's (hereafter referred to as Indigenous(1)) needs is crucial to ensure culturally appropriate evidence-based strategies are developed to improve health. However, concerns surrounding this research exist, arising from some previous research lacking community consultation, resulting in little community benefit or infringing on important cultural values. Values and Ethics: Guidelines for Ethical conduct in Aboriginal and Torres Strait Islander Health Research (hereafter referred to as Values and Ethics), developed by The National Health and Medical Research Council of Australia in 2003, is the ethical standard for Indigenous-focused health research. Researchers must address its Values in research design and conduct. However, its impact on research processes is unclear. Local Protocols should also be considered. This review aims to systematically examine practices related to Values and Ethics, Local Protocols and the processes of conducting Indigenous-focused primary healthcare research in collaboration with external researchers. The following electronic databases and grey literature will be searched (2003 to current): MEDLINE, EMBASE, CINAHL, Informit and HealthInfoNet--an Indigenous-specific research and program website. Indigenous-focused research will be included. Research must be conducted in one or more primary healthcare services, in collaboration with external researchers and with a focus on social and emotional well being. One reviewer will review titles and abstracts to remove obviously irrelevant research articles. Full-text research articles will be retrieved and independently examined by two reviewers. Data and quality assessment will be completed by one reviewer and verified by a second reviewer. Quality will be assessed using modified versions of established quality assessment tools. This review will provide information on research processes and the impact of Values and Ethics on

  14. Aespoe hard rock laboratory. Current research projects 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-31

    In 1986 SKB decided to construct the Aespoe Hard Rock Laboratory (HRL) in order to provide an opportunity for research, development and demonstration in a realistic and undisturbed underground rock environment down to the depth planned for the future deep repository. The focus of current and future work is on development and testing of site characterization methods, verification of models describing the function of the natural and engineered barriers and development, testing, and demonstration of repository technology. The program has been organised so that all important steps in the development of a repository are covered, in other words the Aespoe HRL constitutes a `dress rehearsal` for the Swedish deep geological repository for spent fuel and other long-lived waste. Geoscientific investigations on Aespoe and nearby islands began in 1986. Aespoe was selected as the site for the laboratory in 1988. Construction of the facility, which reaches a depth of 460 m below the surface, began in 1990 and was completed in 1995. A major milestone had been reached in 1996 with the completion of the pre-investigation and construction phases of the Aespoe HRL. The comprehensive research conducted has permitted valuable development and verification of site characterization methods applied from the ground surface, boreholes, and underground excavations. The results of this research are summarised in the book `Aespoe Hard Rock Laboratory - 10 years of Research` published by SKB in 1996. The Operating Phase of the Aespoe HRL began in 1995 and is expected to continue for 15-20 years, that is until the first stage of the development of the Swedish deep geological repository for spent nuclear fuel is expected to be completed. A number of research projects were initiated at the start of the Operating Phase. Most of these projects have made substantial progress since then and important results have been obtained. The purpose of this brochure is to provide a brief presentation of the

  15. Aespoe hard rock laboratory. Current research projects 1998

    International Nuclear Information System (INIS)

    1998-01-01

    In 1986 SKB decided to construct the Aespoe Hard Rock Laboratory (HRL) in order to provide an opportunity for research, development and demonstration in a realistic and undisturbed underground rock environment down to the depth planned for the future deep repository. The focus of current and future work is on development and testing of site characterization methods, verification of models describing the function of the natural and engineered barriers and development, testing, and demonstration of repository technology. The program has been organised so that all important steps in the development of a repository are covered, in other words the Aespoe HRL constitutes a 'dress rehearsal' for the Swedish deep geological repository for spent fuel and other long-lived waste. Geoscientific investigations on Aespoe and nearby islands began in 1986. Aespoe was selected as the site for the laboratory in 1988. Construction of the facility, which reaches a depth of 460 m below the surface, began in 1990 and was completed in 1995. A major milestone had been reached in 1996 with the completion of the pre-investigation and construction phases of the Aespoe HRL. The comprehensive research conducted has permitted valuable development and verification of site characterization methods applied from the ground surface, boreholes, and underground excavations. The results of this research are summarised in the book 'Aespoe Hard Rock Laboratory - 10 years of Research' published by SKB in 1996. The Operating Phase of the Aespoe HRL began in 1995 and is expected to continue for 15-20 years, that is until the first stage of the development of the Swedish deep geological repository for spent nuclear fuel is expected to be completed. A number of research projects were initiated at the start of the Operating Phase. Most of these projects have made substantial progress since then and important results have been obtained. The purpose of this brochure is to provide a brief presentation of the

  16. Livestock in biomedical research: history, current status and future prospective.

    Science.gov (United States)

    Polejaeva, Irina A; Rutigliano, Heloisa M; Wells, Kevin D

    2016-01-01

    Livestock models have contributed significantly to biomedical and surgical advances. Their contribution is particularly prominent in the areas of physiology and assisted reproductive technologies, including understanding developmental processes and disorders, from ancient to modern times. Over the past 25 years, biomedical research that traditionally embraced a diverse species approach shifted to a small number of model species (e.g. mice and rats). The initial reasons for focusing the main efforts on the mouse were the availability of murine embryonic stem cells (ESCs) and genome sequence data. This powerful combination allowed for precise manipulation of the mouse genome (knockouts, knockins, transcriptional switches etc.) leading to ground-breaking discoveries on gene functions and regulation, and their role in health and disease. Despite the enormous contribution to biomedical research, mouse models have some major limitations. Their substantial differences compared with humans in body and organ size, lifespan and inbreeding result in pronounced metabolic, physiological and behavioural differences. Comparative studies of strategically chosen domestic species can complement mouse research and yield more rigorous findings. Because genome sequence and gene manipulation tools are now available for farm animals (cattle, pigs, sheep and goats), a larger number of livestock genetically engineered (GE) models will be accessible for biomedical research. This paper discusses the use of cattle, goats, sheep and pigs in biomedical research, provides an overview of transgenic technology in farm animals and highlights some of the beneficial characteristics of large animal models of human disease compared with the mouse. In addition, status and origin of current regulation of GE biomedical models is also reviewed.

  17. Symbolic Interaction and Applied Social Research: A FOCUS ON TRANSLATIONAL SCIENCE RESEARCH1.

    Science.gov (United States)

    Kotarba, Joseph A

    2014-08-01

    In symbolic interaction, a traditional yet unfortunate and unnecessary distinction has been made between basic and applied research. The argument has been made that basic research is intended to generate new knowledge, whereas applied research is intended to apply knowledge to the solution of practical (social and organizational) problems. I will argue that the distinction between basic and applied research in symbolic interaction is outdated and dysfunctional. The masters of symbolic interactionist thought have left us a proud legacy of shaping their scholarly thinking and inquiry in response to and in light of practical issues of the day (e.g., Znaniecki, and Blumer). Current interactionist work continues this tradition in topical areas such as social justice studies. Applied research, especially in term of evaluation and needs assessment studies, can be designed to serve both basic and applied goals. Symbolic interaction provides three great resources to do this. The first is its orientation to dynamic sensitizing concepts that direct research and ask questions instead of supplying a priori and often impractical answers. The second is its orientation to qualitative methods, and appreciation for the logic of grounded theory. The third is interactionism's overall holistic approach to interfacing with the everyday life world. The primary illustrative case here is the qualitative component of the evaluation of an NIH-funded, translational medical research program. The qualitative component has provided interactionist-inspired insights into translational research, such as examining cultural change in medical research in terms of changes in the form and content of formal and informal discourse among scientists; delineating the impact of significant symbols such as "my lab" on the social organization of science; and appreciating the essence of the self-concept "scientist" on the increasingly bureaucratic and administrative identities of medical researchers. This

  18. Aberrations due to solenoid focusing of a multiply charged high-current ion beam

    CERN Document Server

    Grégoire, G; Lisi, N; Schnuriger, J C; Scrivens, R; Tambini, J

    2000-01-01

    At the output of a laser ion source, a high current of highly charged ions with a large range of charge states is available. The focusing of such a beam by magnetic elements causes a nonlinear space-charge field to develop which can induce large aberrations and emittance growth in the beam. Simulation of the beam from the CERN laser ion source will be presented for an ideal magnetic and electrostatic system using a radially symmetric model. In addition, the three dimensional software KOBRA3 is used for the simulation of the solenoid line. The results of these simulations will be compared with experiments performed on the CERN laser ion source with solenoids (resulting in a hollow beam) and a series of gridded electrostatic lenses. (5 refs).

  19. Optimization of Superconducting Focusing Quadrupoles for the HighCurrent Experiment

    Energy Technology Data Exchange (ETDEWEB)

    Sabbi, GianLuca; Gourlay, Steve; Gung, Chen-yu; Hafalia, Ray; Lietzke, Alan; Martovetski, Nicolai; Mattafirri, Sara; Meinke, Rainer; Minervini, Joseph; Schultz, Joel; Seidl, Peter

    2005-09-16

    The Heavy Ion Fusion (HIF) program is progressing through a series of physics and technology demonstrations leading to an inertial fusion power plant. The High Current Experiment (HCX) at Lawrence Berkeley National Laboratory is exploring the physics of intense beams with high line-charge density. Superconducting focusing quadrupoles have been developed for the HCX magnetic transport studies. A baseline design was selected following several pre-series models. Optimization of the baseline design led to the development of a first prototype that achieved a conductor-limited gradient of 132 T/m in a 70 mm bore, without training, with measured field errors at the 0.1% level. Based on these results, the magnet geometry and fabrication procedures were adjusted to improve the field quality. These modifications were implemented in a second prototype. In this paper, the optimized design is presented and comparisons between the design harmonics and magnetic measurements performed on the new prototype are discussed.

  20. What should autism research focus upon? Community views and priorities from the United Kingdom

    Science.gov (United States)

    Dinsmore, Adam; Charman, Tony

    2014-01-01

    The rise in the measured prevalence of autism has been accompanied by much new research and research investment internationally. This study sought to establish whether the pattern of current UK autism research funding maps on to the concerns of the autism community. Interviews and focus groups were conducted with autistic adults, family members, practitioners and researchers to identify their priorities for research. We also captured the views of a large number of stakeholders via an online survey. There was a clear disparity between the United Kingdom’s pattern of funding for autism research and the priorities articulated by the majority of participants. There was general consensus that future priorities for autism research should lie in those areas that make a difference to people’s day-to-day lives. There needs to be greater involvement of the autism community both in priority setting and in research more broadly to ensure that resources reach where they are most needed and can make the most impact. PMID:24789871

  1. Mixed waste focus area integrated master schedule (current as of May 6, 1996)

    International Nuclear Information System (INIS)

    1996-01-01

    The mission of the Mixed Waste Characterization, Treatment, and Disposal Focus Area (MWFA) is to provide acceptable treatment systems, developed in partnership with users and with the participation of stakeholders, tribal governments, and regulators, that are capable of treating the Department of Energy's (DOE's) mixed wastes. In support of this mission, the MWTA produced the Mixed Waste Focus Area Integrated Technical Baseline Report, Phase I Volume 1, January 16, 1996, which identified a prioritized list of 30 national mixed waste technology deficiencies. The MWFA is targeting funding toward technology development projects that address the current list of deficiencies. A clear connection between the technology development projects and the EM-30 and EM-40 treatment systems that they support is essential for optimizing the MWFA efforts. The purpose of the Integrated Master Schedule (IMS) is to establish and document these connections and to ensure that all technology development activities performed by the MWFA are developed for timely use in those treatment systems. The IMS is a list of treatment systems from the Site Treatment Plans (STPs)/Consent Orders that have been assigned technology development needs with associated time-driven schedules, Technology deficiencies and associated technology development (TD) needs have been identified for each treatment system based on the physical, chemical, and radiological characteristics of the waste targeted for the treatment system. The schedule, the technology development activities, and the treatment system have been verified through the operations contact from the EM-30 organization at the site

  2. Filamentary structures in dense plasma focus: Current filaments or vortex filaments?

    Energy Technology Data Exchange (ETDEWEB)

    Soto, Leopoldo, E-mail: lsoto@cchen.cl; Pavez, Cristian; Moreno, José [Comisión Chilena de Energía Nuclear, CCHEN, Casilla 188-D, Santiago (Chile); Center for Research and Applications in Plasma Physics and Pulsed Power, P4, Departamento de Ciencias Físicas, Facultad de Ciencias Exactas, Universidad Andrés Bello, República 220, Santiago (Chile); Castillo, Fermin [Universidad Nacional Autónoma de México, Cuernavaca, México (Mexico); Veloso, Felipe [Instituto de Física, Pontificia Universidad Católica de Chile, 7820436 Santiago (Chile); Auluck, S. K. H. [Bhabha Atomic Research Center, Mumbai 400 085 (India)

    2014-07-15

    Recent observations of an azimuthally distributed array of sub-millimeter size sources of fusion protons and correlation between extreme ultraviolet (XUV) images of filaments with neutron yield in PF-1000 plasma focus have re-kindled interest in their significance. These filaments have been described variously in literature as current filaments and vortex filaments, with very little experimental evidence in support of either nomenclature. This paper provides, for the first time, experimental observations of filaments on a table-top plasma focus device using three techniques: framing photography of visible self-luminosity from the plasma, schlieren photography, and interferometry. Quantitative evaluation of density profile of filaments from interferometry reveals that their radius closely agrees with the collision-less ion skin depth. This is a signature of relaxed state of a Hall fluid, which has significant mass flow with equipartition between kinetic and magnetic energy, supporting the “vortex filament” description. This interpretation is consistent with empirical evidence of an efficient energy concentration mechanism inferred from nuclear reaction yields.

  3. Production of tightly focused E-beam with high-current accelerators

    International Nuclear Information System (INIS)

    Poukey, J.W.; Mazarakis, M.G.; Frost, C.A.; Ramirez, J.J.

    1991-01-01

    Using numerical modeling the authors study several approaches to the problem of designing an injector to produce a 3-30 kA, 2-4 mm diameter electron beam in the energy range 10-20 MeV. The cathode may be small in diameter and immersed in a strong magnetic field, producing an equilibrium beam for transport to a target (the immersed case). This approach appears to be the most promising for applications such as radiography, and the authors shall emphasize it in this paper. The alternative is the conventional non-immersed cathode, in which the beam from a larger-radius, cold-beam cathode is focused with magnetic lenses to a small spot on the target. Because the non-immersed cathode, in which the beam from a larger-radius, cold-beam cathode is focused with a magnetic lenses to a small spot on the target. Because the non-immersed case has been extensively studied, and because it has advantages for these purposes, the authors shall only discuss a few of the non-immersed-cathode injector studies, primarily for purposes of comparison. Either type of diode is to be powered by an inductive voltage adder based on the successful SABRE/Hermes III/RADLAC (SMILE) magnetically-insulated-transmission-line design concepts. A possible variation uses a re-entrant geometry with low electric stresses so that only the cathode face emits. The authors discuss issues such as dumping excess current and voltage dependence of the focus

  4. [Video game and internet addiction. The current state of research].

    Science.gov (United States)

    Rehbein, F; Mößle, T; Arnaud, N; Rumpf, H-J

    2013-05-01

    The use of interactive screen media is widespread and for some users leads to pathological symptoms that are phenomenologically similar to signs of addictive disorders. Addictive use of computer games and other Internet applications, such as social media can be distinguished. In the past standard criteria to classify this new disorder were lacking. In DSM-5, nine criteria are proposed for diagnosing Internet gaming disorder. The focus is currently on video games as most studies have been done in this field. Prevalence estimations are difficult to interpret due to the lack of standard diagnostic measures and result in a range of the frequency of Internet addiction between 1 % and 4.2 % in the general German population. Rates are higher in younger individuals. For computer game addiction prevalence rates between 0.9 % and 1.7  % can be found in adolescents. Despite substantial comorbidity among those affected current research points to addictive media use as a stand-alone disorder.

  5. Current status and prospect on the radioactive waste management program in the Republic of Korea. Focusing on recent development

    International Nuclear Information System (INIS)

    Park, Hyun-Soo; Chang, In-Soon

    1996-01-01

    Since its first commercial operation at Kori near the city of Pusan in 1978, nuclear energy has become one of the prime resources for the electricity. However, proper treatment of its byproducts, radioactive wastes, has been the national concern. Despite vigorous effort by the Korean Government and NEMAC(Nuclear Environment Management Center), the series of attempts for the site selection to build the national radioactive waste complex has been ruined. After the failure at Guleop Island, the Government recently amended its policy so that the major tasks on the management program of radioactive wastes shall be transferred to KEPCO(Korea Electric Power Corporation), sole national electric utility, while the current authority, KAERI(Korea Atomic Energy Research Institute)/NEMAC is limited to focus on the research and development in the safe management of spent fuels. Detailed plan to support the Government redirection is under discussion among concerned institutes. (author)

  6. Collaborative Research: Dynamics of Electrostatic Solitary Waves on Current Layers

    Energy Technology Data Exchange (ETDEWEB)

    Pickett, Jolene S.

    2012-10-31

    The research carried out under the subject grant has provided insight into the generation of Electrostatic Solitary Waves (ESWs), which are nonlinear structures observed in space plasma data. These ESWs, appearing as pulses in the electric field time series data, represent the presence of several hundred meters to kilometer size positive potential structures, similar to champagne bubbles, where the electrons have been depleted, and which travel along Earth's magnetic field lines. The laboratory experiments carried out at the UCLA LAPD under the grant allowed us the opportunity to change various plasma and field conditions within the plasma device, and experiment with injection of suprathermal electron beams, in order to create ESWs. This then allowed us to determine the most likely method of generation of the ESWs. By comparing the properties of the ESWs observed in the LAPD to those observed in space and the plasma and field conditions under which those ESWs were observed in both locations, we were able to evaluate various ESW generation mechanisms. The findings of the laboratory experiments are that ESWs are generated through a lower hybrid instability. The ESWs observed in Earth's auroral current regions have similar characteristics to those generated by the laboratory when referenced to basic plasma and field characteristics, leading us to the conclusion that the lower hybrid drift instability is certainly a possibility for generation of the ESWs, at least in the auroral (northern/southern lights) regions. Due to space instrumentation insufficiencies and the limitations on telemetry, and thus poor time resolution, it is not possible to determine absolutely what generates these bubbles in space, but the laboratory experiments and supporting simulations have helped us to further our understanding of the processes under which they are generated. The public benefits from the findings of this research because the research is focused on current layers

  7. Reduction in spread of excitation from current focusing at multiple cochlear locations in cochlear implant users.

    Science.gov (United States)

    Padilla, Monica; Landsberger, David M

    2016-03-01

    Channel interaction from a broad spread of excitation is likely to be a limiting factor in performance by cochlear implant users. Although partial tripolar stimulation has been shown to reduce spread of excitation, the magnitude of the reduction is highly variable across subjects. Because the reduction in spread of excitation is typically only measured at one electrode for a given subject, the degree of variability across cochlear locations is unknown. The first goal of the present study was to determine if the reduction in spread of excitation observed from partial tripolar current focusing systematically varies across the cochlea. The second goal was to measure the variability in reduction of spread of excitation relative to monopolar stimulation across the cochlea. The third goal was to expand upon previous results that suggest that scaling of verbal descriptors can be used to predict the reduction in spread of excitation, by increasing the limited number of sites previously evaluated and verify the relationships remain with the larger dataset. The spread of excitation for monopolar and partial tripolar stimulation was measured at 5 cochlear locations using a psychophysical forward masking task. Results of the present study suggest that although partial tripolar stimulation typically reduces spread of excitation, the degree of reduction in spread of excitation was found to be highly variable and no effect of cochlear location was found. Additionally, subjective scaling of certain verbal descriptors (Clean/Dirty, Pure/Noisy) correlated with the reduction in spread of excitation suggesting sound quality scaling might be used as a quick clinical estimate of channels providing a reduction in spread of excitation. This quick scaling technique might help clinicians determine which patients would be most likely to benefit from a focused strategy. Copyright © 2016 Elsevier B.V. All rights reserved.

  8. Family-Focused Autism Spectrum Disorder Research: A Review of the Utility of Family Systems Approaches

    Science.gov (United States)

    Cridland, Elizabeth K.; Jones, Sandra C.; Magee, Christopher A.; Caputi, Peter

    2014-01-01

    A family member with an autism spectrum disorder presents pervasive and bidirectional influences on the entire family system, suggesting a need for family-focused autism spectrum disorder research. While there has been increasing interest in this research area, family-focused autism spectrum disorder research can still be considered relatively…

  9. Developing a plasma focus research training system for the fusion energy age

    International Nuclear Information System (INIS)

    Lee, S.

    2014-01-01

    The 3 kJ UNU/ICTP Plasma Focus Facility is the most significant device associated with the AAAPT (Asian African Association for Plasma Training). In original and modified/upgraded form it has trained generations of plasma focus (PF) researchers internationally, producing many PhD theses and peer-reviewed papers. The Lee Model code was developed for the design of this PF. This code has evolved to cover all PF machines for design, interpretation and optimization, for derivation of radiation scaling laws; and to provide insights into yield scaling limitations, radiative collapse, speed-enhanced and current-stepped PF variants. As example of fresh perspectives derivable from this code, this paper presents new results on energy transfers of the axial and radial phases of generalized PF devices. As the world moves inexorably towards the Fusion Energy Age it becomes ever more important to train plasma fusion researchers. A recent workshop in Nepal shows that demand for such training continues. Even commercial project development consultants are showing interest. We propose that the AAAPT-proven research package be upgraded, by modernizing the small PF for extreme modes of operation, switchable from the typical strong-focus mode to a slow-mode which barely pinches, thus producing a larger, more uniform plasma stream with superior deposition properties. Such a small device would be cost-effective and easily duplicated, and have the versatility of a range of experiments from intense multi-radiation generation and target damage studies to superior advanced-materials deposition. The complementary code is used to reference experiments up to the largest existing machine. This is ideal for studying machine limitations and scaling laws and to suggest new experiments. Such a modernized versatile PF machine complemented by the universally versatile code would extend the utility of the PF experience; so that AAAPT continues to provide leadership in pulsed plasma research training in

  10. Dose-current discharge correlation analysis in a Mather type Plasma Focus device for medical applications

    Science.gov (United States)

    Sumini, M.; Mostacci, D.; Tartari, A.; Mazza, A.; Cucchi, G.; Isolan, L.; Buontempo, F.; Zironi, I.; Castellani, G.

    2017-11-01

    In a Plasma Focus device the plasma collapses into the pinch where it reaches thermonuclear conditions for a few tens of nanoseconds, becoming a multi-radiation source. The nature of the radiation generated depends on the gas filling the chamber and the device working parameters. The self-collimated electron beam generated in the backward direction with respect to the plasma motion is one of the main radiation sources of interest also for medical applications. The electron beam may be guided against a high Z material target to produce an X-ray beam. This technique offers an ultra-high dose rate source of X-rays, able to deliver during the pinch a massive dose (up to 1 Gy per discharge for the PFMA-3 test device), as measured with EBT3 GafchromicⒸfilm tissue equivalent dosimeters. Given the stochastic behavior of the discharge process, a reliable on-line estimate of the dose-delivered is a very challenging task, in some way preventing a systematic application as a potentially interesting therapy device. This work presents an approach to linking the dose registered by the EBT3 GafchromicⒸfilms with the information contained in the signal recorded during the current discharge process. Processing the signal with the Wigner-Ville distribution, a spectrogram was obtained, displaying the information on intensity at various frequency scales, identifying the band of frequencies representative of the pinch events and define some patterns correlated with the dose.

  11. Using the Human Systems Simulation Laboratory at Idaho National Laboratory for Safety Focused Research

    Energy Technology Data Exchange (ETDEWEB)

    Joe, Jeffrey .C; Boring, Ronald L.

    2016-07-01

    Under the United States (U.S.) Department of Energy (DOE) Light Water Reactor Sustainability (LWRS) program, researchers at Idaho National Laboratory (INL) have been using the Human Systems Simulation Laboratory (HSSL) to conduct critical safety focused Human Factors research and development (R&D) for the nuclear industry. The LWRS program has the overall objective to develop the scientific basis to extend existing nuclear power plant (NPP) operating life beyond the current 60-year licensing period and to ensure their long-term reliability, productivity, safety, and security. One focus area for LWRS is the NPP main control room (MCR), because many of the instrumentation and control (I&C) system technologies installed in the MCR, while highly reliable and safe, are now difficult to replace and are therefore limiting the operating life of the NPP. This paper describes how INL researchers use the HSSL to conduct Human Factors R&D on modernizing or upgrading these I&C systems in a step-wise manner, and how the HSSL has addressed a significant gap in how to upgrade systems and technologies that are built to last, and therefore require careful integration of analog and new advanced digital technologies.

  12. Current and Future Research Directions in Requirements Engineering

    Science.gov (United States)

    Cheng, Betty H. C.; Atlee, Joanne M.

    In this paper, we review current requirements engineering (RE) research and identify future research directions suggested by emerging software needs. First, we overview the state of the art in RE research. The research is considered with respect to technologies developed to address specific requirements tasks, such as elicitation, modeling, and analysis. Such a review enables us to identify mature areas of research, as well as areas that warrant further investigation. Next, we review several strategies for performing and extending RE research results, to help delineate the scope of future research directions. Finally, we highlight what we consider to be the “hot” current and future research topics, which aim to address RE needs for emerging systems of the future.

  13. Biotechnological Utilization with a Focus on Anaerobic Treatment of Cheese Whey: Current Status and Prospects

    Directory of Open Access Journals (Sweden)

    Aspasia A. Chatzipaschali

    2012-09-01

    Full Text Available Cheese whey utilization is of major concern nowadays. Its high organic matter content, in combination with the high volumes produced and limited treatment options make cheese whey a serious environmental problem. However, the potential production of biogas (methane, hydrogen or other marketable products with a simultaneous high COD reduction through appropriate treatment proves that cheese whey must be considered as an energy resource rather than a pollutant. The presence of biodegradable components in the cheese whey coupled with the advantages of anaerobic digestion processes over other treatment methods makes anaerobic digestion an attractive and suitable treatment option. This paper intends to review the most representative applications of anaerobic treatment of cheese whey currently being exploited and under research. Moreover, an effort has been made to categorize the common characteristics of the various research efforts and find a comparative basis, as far as their results are concerned. In addition, a number of dairy industries already using such anaerobic digestion systems are presented.

  14. Current Research Therapeutic Strategies for Alzheimer’s Disease Treatment

    Directory of Open Access Journals (Sweden)

    Jaume Folch

    2016-01-01

    Full Text Available Alzheimer’s disease (AD currently presents one of the biggest healthcare issues in the developed countries. There is no effective treatment capable of slowing down disease progression. In recent years the main focus of research on novel pharmacotherapies was based on the amyloidogenic hypothesis of AD, which posits that the beta amyloid (Aβ peptide is chiefly responsible for cognitive impairment and neuronal death. The goal of such treatments is (a to reduce Aβ production through the inhibition of β and γ secretase enzymes and (b to promote dissolution of existing cerebral Aβ plaques. However, this approach has proven to be only modestly effective. Recent studies suggest an alternative strategy centred on the inhibition of the downstream Aβ signalling, particularly at the synapse. Aβ oligomers may cause aberrant N-methyl-D-aspartate receptor (NMDAR activation postsynaptically by forming complexes with the cell-surface prion protein (PrPC. PrPC is enriched at the neuronal postsynaptic density, where it interacts with Fyn tyrosine kinase. Fyn activation occurs when Aβ is bound to PrPC-Fyn complex. Fyn causes tyrosine phosphorylation of the NR2B subunit of metabotropic glutamate receptor 5 (mGluR5. Fyn kinase blockers masitinib and saracatinib have proven to be efficacious in treating AD symptoms in experimental mouse models of the disease.

  15. Securing Canada’s Information-Technology Infrastructure: Context, Principles, and Focus Areas of Cybersecurity Research

    Directory of Open Access Journals (Sweden)

    Dan Craigen

    2013-07-01

    Full Text Available This article addresses the challenges of cybersecurity and ultimately the provision of a stable and resilient information-technology infrastructure for Canada and, more broadly, the world. We describe the context of current cybersecurity challenges by synthesizing key source material whose importance was informed by our own real-world experiences. Furthermore, we present a checklist of guiding principles to a unified response, complete with a set of action-oriented research topics that are linked to known operational limitations. The focus areas are used to drive the formulation of a unified and relevant research and experimental development program, thereby moving us towards a stable and resilient cyberinfrastructure. When cybersecurity is viewed as an inherently interdisciplinary problem of societal concern, we expect that fundamentally new research perspectives will emerge in direct response to domain-specific protection requirements for information-technology infrastructure. Purely technical responses to cybersecurity challenges will be inadequate because human factors are an inherent aspect of the problem. This article will interest managers and entrepreneurs. Senior management teams can assess new technical developments and product releases to fortify their current security solutions, while entrepreneurs can harness new opportunities to commercialize novel technology to solve a high-impact cybersecurity problem..

  16. Current status and a short history of grey literature. Focusing on the international conference on grey literature

    International Nuclear Information System (INIS)

    Ikeda, Kiyoshi

    2010-01-01

    'Grey literature' is a loosely defined term whose application is rather complex, but it is also an important source of information for academic researchers. Today, the spread of the Internet has led to changes not only in the circulation but also in the role and definition of 'grey literature'. This article therefore presents a short history of the definition of 'grey literature', with central focus on topics discussed by the International Conference on Grey Literature. After this, the current status and future prospects of 'grey literature' in the digital society are described. Finally, the article introduces the JAEA Library's activities on 'grey literature', particularly the acquisition of proceedings and the editing and dissemination of the JAEA Reports (technical reports of JAEA). (author)

  17. Work-life balance of nursing faculty in research- and practice-focused doctoral programs.

    Science.gov (United States)

    Smeltzer, Suzanne C; Sharts-Hopko, Nancy C; Cantrell, Mary Ann; Heverly, Mary Ann; Jenkinson, Amanda; Nthenge, Serah

    2015-01-01

    The growing shortage of nursing faculty and the need for faculty to teach doctoral students to address the shortage call for examination of factors that may contribute to the shortage, including those that are potentially modifiable, including work-life balance.This descriptive study examined work-life balance of a national sample of nursing faculty teaching in research-focused and practice-focused doctoral programs. Data were collected through an online survey of 554 doctoral program faculty members to identify their perceptions of work-life balance and predictors of work-life balance. Work-life balance scores indicated better work-life balance than expected. Factors associated with good work-life balance included higher academic rank, having tenure, older age, years in education, current faculty position, and no involvement in clinical practice. Current faculty position was the best predictor of work-life balance. Although work-life balance was viewed positively by study participants, efforts are needed to strengthen factors related to positive work/life in view of the increasing workload of doctoral faculty as the numbers of doctoral students increase and the number of seasoned faculty decrease with anticipated waves of retirements. Copyright © 2015 Elsevier Inc. All rights reserved.

  18. Recent advances in addictive disorders. Prevention. Current research and trends.

    Science.gov (United States)

    Kumpfer, K L; Hopkins, R

    1993-03-01

    The AOD prevention programs of the 1990s should be resiliency-focused and include interventions of sufficient dosage and strength. Although some child behavioral technology exists to tackle successfully changes in resiliency, additional prevention strategies need to be developed and studied. In some way, the prevention field is hampered by the lack of sufficient research in the child and adolescent psychiatry and psychology fields, that includes transactional research in parenting and child rearing for high-risk youth. We simply do not know enough to determine how parents and other adults can best foster resilience in children. Questions that arise include how much to protect children from environmental stressors and how much to push them to confront new life stressors in the form of challenges to develop new skills or talents. There are no simple answers to these questions, but a number of useful guidelines could help parents and teachers to increase resilience in youth. Some of the guidelines currently being stressed include developing in youth an increased sense of responsibility for their own success, helping them to identify their talents, motivating them to dedicate their lives to helping society rather than feeling their only purpose in life is to be consumers, providing realistic appraisals and feedback for youth rather than graciously building up their self-esteem, stressing multicultural competence in an ever-shrinking world, encouraging and valuing education and skills training, increasing cooperative solutions to problems rather than competitive or aggressive solutions, and increasing a sense of responsibility for others and caring for others. Clearly, these are important objectives for creating the type of citizens that can make American strong in the twentieth century.

  19. Educational Research in Mainland China: Current Situation and Developmental Trends

    Science.gov (United States)

    Sun, Miantao

    2011-01-01

    The influence of Confucian culture in Chinese Mainland China is reflected in the current situation and contextual trends of educational research content of educational thought of Confucianism, educational issues grounded on theoretical views of Confucianism, and the influence of the inclusiveness of Confucianism. In terms of research method, the…

  20. Current research projects on traffic conflicts technique studies.

    NARCIS (Netherlands)

    Hondel, M. van den & and Kraay, J.H.

    1979-01-01

    A review of current research concerning the development, evaluation and use of the traffic conflicts technique is presented. The 32 studies, selected from the IRRD data base, are listed alphabetically by names of countries and under countries by names of research organizations. The IRRD descriptions

  1. Precincts and Prospects in the Use of Focus Groups in Social and Behavioral Science Research

    Science.gov (United States)

    Sagoe, Dominic

    2012-01-01

    Over the past few years, the focus group method has assumed a very important role as a method for collecting qualitative data in social and behavioural science research. This article elucidates theoretical and practical problems and prospects associated with the use of focus groups as a qualitative research method in social and behavioural science…

  2. Focus group interview: an underutilized research technique for improving theory and practice in health education.

    Science.gov (United States)

    Basch, C E

    1987-01-01

    The purpose of this article is to increase awareness about and stimulate interest in using focus group interviews, a qualitative research technique, to advance the state-of-the-art of education and learning about health. After a brief discussion of small group process in health education, features of focus group interviews are presented, and a theoretical framework for planning a focus group study is summarized. Then, literature describing traditional and health-related applications of focus group interviews is reviewed and a synthesis of methodological limitations and advantages of this technique is presented. Implications are discussed regarding: need for more inductive qualitative research in health education; utility of focus group interviews for research and for formative and summative evaluation of health education programs; applicability of marketing research to understanding and influencing consumer behavior, despite notable distinctions between educational initiatives and marketing; and need for professional preparation faculty to consider increasing emphasis on qualitative research methods.

  3. Focus group reflections on the current and future state of cognitive assessment tools in geriatric health care

    Directory of Open Access Journals (Sweden)

    Whitehead JC

    2015-06-01

    Full Text Available Jocelyne C Whitehead,1 Sara A Gambino,1 Jeffrey D Richter,2 Jennifer D Ryan1,3,41Rotman Research Institute, Baycrest, 2Independent Human Factors Consultant, Toronto, ON, Canada; 3Department of Psychology, 4Department of Psychiatry, University of Toronto, Toronto, ON, CanadaObjective: This study provides insight into the thoughts and opinions of geriatric health-care professionals toward cognitive assessments and the use of emerging technologies, such as eye-tracking, to supplement current tools.Methods: Two focus group sessions were conducted with nurses and physicians who routinely administer neurocognitive assessments to geriatric populations. Video recordings of the focus group sessions were transcribed and a thematic analysis was performed.Results: Participants reported the need for assessment and diagnostic tools that are accessible and efficient, and that are capable of accommodating the rapid growth in the aging population. The prevalence of more complex ailments experienced by older adults has had repercussions in the quality of care that the clients receive, and has contributed to lengthy wait times and resource shortages. Health-care professionals stated that they are hampered by the disjointed structure of the health-care system and that they would benefit from a more efficient allocation of responsibilities made possible through tools that did not require extensive training or certification. Eyetracking-based cognitive assessments were thought to strongly complement this system, yet it was thought that difficulty would be faced in gaining the support and increased uptake by health-care professionals due to the nonintuitive relationship between eyetracking and cognition.Conclusion: The findings suggest that health-care professionals are receptive to the use of eyetracking technology to assess for cognitive health as it would conserve resources by allowing frontline staff to administer assessments with minimal training

  4. Research Experience in Psychiatry Residency Programs Across Canada: Current Status

    Science.gov (United States)

    Shanmugalingam, Arany; Ferreria, Sharon G; Norman, Ross M G; Vasudev, Kamini

    2014-01-01

    Objective: To determine the current status of research experience in psychiatry residency programs across Canada. Method: Coordinators of Psychiatric Education (COPE) resident representatives from all 17 psychiatry residency programs in Canada were asked to complete a survey regarding research training requirements in their programs. Results: Among the 17 COPE representatives, 15 completed the survey, representing 88% of the Canadian medical schools that have a psychiatry residency program. Among the 15 programs, 11 (73%) require residents to conduct a scholarly activity to complete residency. Some of these programs incorporated such a requirement in the past 5 years. Ten respondents (67%) reported availability of official policy and (or) guidelines on resident research requirements. Among the 11 programs that have a research requirement, 10 (91%) require residents to complete 1 scholarly activity; 1 requires completion of 2 scholarly activities. Eight (53%) residency programs reported having a separate research track. All of the programs have a research coordinator and 14 (93%) programs provide protected time to residents for conducting research. The 3 most common types of scholarly activities that qualify for the mandatory research requirement are a full independent project (10 programs), a quality improvement project (8 programs), and assisting in a faculty project (8 programs). Six programs expect their residents to present their final work in a departmental forum. None of the residency programs require publication of residents’ final work. Conclusions: The current status of the research experience during psychiatry residency in Canada is encouraging but there is heterogeneity across the programs. PMID:25565474

  5. Current steering and current focusing in cochlear implants: comparison of monopolar, tripolar, and virtual channel electrode configurations.

    Science.gov (United States)

    Berenstein, Carlo K; Mens, Lucas H M; Mulder, Jef J S; Vanpoucke, Filiep J

    2008-04-01

    To compare the effects of Monopole (Mono), Tripole (Tri), and "Virtual channel" (Vchan) electrode configurations on spectral resolution and speech perception in a crossover design. Nine experienced adults who received an Advanced Bionics CII/90K cochlear implant participated in a crossover design using three experimental strategies for 2 wk each. Three strategies were compared: (1) Mono; (2) Tri with current partly returning to adjacent electrodes and partly (25 or 75%) to the extracochlear reference; and (3) a monopolar "Vchan" strategy creating seven intermediate channels between two contacts. Each strategy was a variant of the standard "HiRes" processing strategy using 14 channels and 1105 pulses/sec/ channel, and a pulse duration of 32 microsec/phase. Spectral resolution was measured using broadband noise with a sinusoidally rippled spectral envelope with peaks evenly spaced on a logarithmic frequency scale. Speech perception was measured for monosyllables in quiet and in steady-state and fluctuating noises. Subjective comments on music experience and preferences in everyday use were assessed through questionnaires. Thresholds and most comfortable levels with Mono and Vchan were both significantly lower than levels with Tri. Spectral resolution was significantly higher with Tri than with Mono; spectral resolution with Vchan did not differ significantly from the other configurations. Moderate but significant correlations between word recognition and spectral resolution were found in speech in quiet and fluctuating noise. For speech in quiet, word recognition was best with Mono and worst with Vchan; Tri did not significantly differ from the other configurations. Pooled across the noise conditions, word recognition was best with Tri and worst with Vchan (Mono did not significantly differ from the other configurations). These differences were small and insufficient to result in a clear increase in performance across subjects if the result from the best

  6. Curating research data a handbook of current practice

    CERN Document Server

    Johnston, Lisa R

    2017-01-01

    Curating Research Data, Volume Two: A Handbook of Current Practice guides you across the data lifecycle through the practical strategies and techniques for curating research data in a digital repository setting. The data curation steps for receiving, appraising, selecting, ingesting, transforming, describing, contextualizing, disseminating, and preserving digital research data are each explored, and then supplemented with detailed case studies written by more than forty international practitioners from national, disciplinary, and institutional data repositories. The steps in this volume detail the sequential actions that you might take to curate a data set from receiving the data (Step 1) to eventual reuse (Step 8). Data curators, archivists, research data management specialists, subject librarians, institutional repository managers, and digital library staff will benefit from these current and practical approaches to data curation.

  7. International consensus on use of focused ultrasound for painful bone metastases : Current status and future directions

    NARCIS (Netherlands)

    Huisman, Merel; ter Haar, Gail; Napoli, Alessandro; Hananel, Arik; Ghanouni, Pejman; Lövey, György; Nijenhuis, Robbert J; van den Bosch, Maurice A A J; Rieke, Viola; Majumdar, Sharmila; Marchetti, Luca; Pfeffer, Raphael M; Hurwitz, Mark D

    2015-01-01

    Focused ultrasound surgery (FUS), in particular magnetic resonance guided FUS (MRgFUS), is an emerging non-invasive thermal treatment modality in oncology that has recently proven to be effective for the palliation of metastatic bone pain. A consensus panel of internationally recognised experts in

  8. THE FOCUS OF COMPANIES ON CLIENTS A MAJOR TREND IN THE CURRENT BUSINESS ENVIRONMENT

    OpenAIRE

    SOCA, Diana

    2012-01-01

    Under the impact of economic dynamism, sharpening competition, globalization and computerization, the late twentieth century is characterized by moving from a transactional to a relational marketing in which companies focus on developing relationships with customers, increasing their level of satisfaction and ultimately gaining their loyalty.

  9. Current trends in chloroplast genome research | Khan | African ...

    African Journals Online (AJOL)

    comprise of DOGMA for annotation, SCAN-SE, ARAGON and PREP suit for RNA analyses and CG viewer for circular map construction/comparative analysis. Faster algorithms for gene-order based phylogenetic reconstruction and bootstrap analysis have attracted the attention of research community. Current trends in ...

  10. Current Research on Adolescence and its Program Implications.

    Science.gov (United States)

    Cvetkovich, George; Grote, Barbara

    This paper discusses program implications of research on adolescents. A brief historical review of teenage sexuality is presented in order to put current information in perspective. The present increase in teenage fertility is seen as part of a larger epidemic failure of socialization. A number of recent studies are reviewed and synthesized,…

  11. Plant cell engineering: current research, application and future prospects

    International Nuclear Information System (INIS)

    Wang Xunqing; Liu Luxiang

    2008-01-01

    This paper reviewed the current status of basic research in plant cell engineering, highlighted the application of embryo culture, double haploid (DH) technology, protoplast culture and somatic hybridization, somaclonal variation, rapid propagation, and bio-products production of plant-origin, and t he prospects. (authors)

  12. Research on Hearing and Balance--Current and Future Developments.

    Science.gov (United States)

    Snow, James B., Jr.

    1997-01-01

    This article reviews current research that has located disease genes causing hearing impairments, discovered the ability of sensory cells of the inner ear to regenerate, developed vaccines to prevent otitis media, developed programmable hearing aids, improved cochlear implants, and demonstrated the positive effects of physical therapy with balance…

  13. Research on Current Trends and Developments in Library Automation Systems.

    Science.gov (United States)

    Clyde, Laurel A.

    A research project was undertaken in 1992 in order to identify, describe, and analyze current trends and developments in library automation systems and library software. The starting point is work conducted in 1988/1989 that formed the foundation of the book "Computer Software for School Libraries: A Directory." A 1992 survey of software…

  14. Puzzle-solving in psychology : The neo-Galtonian vs. nomothetic research focuses

    NARCIS (Netherlands)

    Vautier, Stephane; Lacot, Emilie; Veldhuis, Michiel

    We compare the neo-Galtonian and nomothetic approaches of psychological research. While the former focuses on summarized statistics that depict average subjects, the latter focuses on general facts of form 'if conditions then restricted outcomes'. The nomothetic approach does not require

  15. Analysis of current trends on the Czech food market with a focus on a healthy lifestyle.

    OpenAIRE

    Bartůňková, Eva

    2013-01-01

    The thesis of this work is to map current trends on the Czech food market with focus on a healthy lifestyle. In particular, it focuses on foodstuff labelling and GDA labels. The paper begins by surveying the development of the healthy lifestyle trend, as well as the activities of the Federation of the Food and Drink Industries of the Czech Republic involved in a healthy lifestyle; furthermore, the work elaborates on segmentation of the consumer and evaluation of a healthy lifestyle, obesity a...

  16. [Current situation of clinical research on impacted premolars].

    Science.gov (United States)

    Liu, Ran-Ran; Tian, Jun

    2018-04-01

    Teeth impaction is a common developmental malformation in oral diseases. Impacted teeth are usually the canines, third molar, central incisors, premolars, and second molars. The prevalence of impaction of maxillary canines and mandibular wisdom teeth is higher than that of other teeth. Most recent studies have focused on the canines and third molars, but research on impacted premolars is limited. In clinical practice, the majority of orthodontic patients require premolar extraction. Thus, impacted premolars play important roles in orthodontic design and prognosis. This article provides an overview of recent research on impacted premolars and summarizes epidemiological features, localizations, and treatments, with the aim of guiding practitioners on orthodontic design and therapy.

  17. Current thinking in medical education research: an overview.

    Science.gov (United States)

    Elledge, R

    2018-04-28

    Medical education is fast becoming a separate focus, and together with their clinical commitments, many clinicians now seek higher qualifications and professional accreditation in the field. Research is also developing, and there is a need for evidence-based practice in education, just as in clinical work. This review gives an overview of research into medical education, and explains the fundamentals of educational theory and the specific considerations for the quantitative and qualitative research methods that pertain to it. It also explains the application of these methods to two growing areas of research: technology-enhanced learning (TEL) and normative ethics in training. Copyright © 2018 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

  18. Current status of high-intensity focused ultrasound for the management of uterine adenomyosis

    International Nuclear Information System (INIS)

    Cheng, Vincent Y. T.

    2017-01-01

    While high-intensity focused ultrasound has been used for some time in the management of uterine fibroids, its effectiveness and safety in managing adenomyosis is less well established. A literature review was performed of all eligible reports using this modality as a treatment for adenomyosis. Relevant publications were obtained from the PubMed electronic database from inception through March 2016. Eleven articles, including information from 1,150 treatments and follow-up data from 990 patients, were reviewed. High-intensity focused ultrasound appears to be effective and safe in the management of symptomatic adenomyosis, and can be considered as an alternative uterine-sparing option for women with this condition

  19. Current status of high-intensity focused ultrasound for the management of uterine adenomyosis

    Energy Technology Data Exchange (ETDEWEB)

    Cheng, Vincent Y. T. [Dept. of Obstetrics and Gynaecology, Queen Mary Hospital, The University of Hong Kong, Hong Kong (China)

    2017-04-15

    While high-intensity focused ultrasound has been used for some time in the management of uterine fibroids, its effectiveness and safety in managing adenomyosis is less well established. A literature review was performed of all eligible reports using this modality as a treatment for adenomyosis. Relevant publications were obtained from the PubMed electronic database from inception through March 2016. Eleven articles, including information from 1,150 treatments and follow-up data from 990 patients, were reviewed. High-intensity focused ultrasound appears to be effective and safe in the management of symptomatic adenomyosis, and can be considered as an alternative uterine-sparing option for women with this condition.

  20. Innovation in Researching the Effects of Frame – Focused Instruction on Second Language Acquisition

    Directory of Open Access Journals (Sweden)

    Elena SOKOLOVA

    2010-01-01

    Full Text Available In the context of globalization the research of innovative teaching methods and techniques becomes relevant. The traditional teaching approach where the training of practice material is preceded by rule-presentation (explanation + mechanical formoriented practice doesn’t meet the requirements of constantly developing rational language processing. Contemporary studies are considering the ways how to allow second language learners to be rational in the sense that their mental models of language functioning are the most optimal. This paper outlines current cognitive perspectives on second language acquisition. Language learning involves the acquisition of frame instructions or input-processing instructions (explanation + structured-input activities. Competence and performance both emerge from the dynamic system of frequently used memorized constructions. Frames are dynamic contextualized activation of stereotyped situations. This system proves to be rational since it aims at optimal reflection of prior first language usage and induces learners to think consciously about some sort of rule in order to work out the meaning. The frame–based instruction consists of activities which present learners with a stimulus and require them to respond choosing the appropriate language form for communication. The targeted feature of such communicative tasks has two aims: 1. to stimulate communicative language use and 2. to target the use of a particular predetermined linguistic feature. The empirical research shows that frame-focused tasks direct learners attention to the meaning realized by the target form. Methodological basis includes some theoretical propositions from recent Relevance theory and cognitive linguistics.

  1. Consciousness and working memory: Current trends and research perspectives.

    Science.gov (United States)

    Velichkovsky, Boris B

    2017-10-01

    Working memory has long been thought to be closely related to consciousness. However, recent empirical studies show that unconscious content may be maintained within working memory and that complex cognitive computations may be performed on-line. This promotes research on the exact relationships between consciousness and working memory. Current evidence for working memory being a conscious as well as an unconscious process is reviewed. Consciousness is shown to be considered a subset of working memory by major current theories of working memory. Evidence for unconscious elements in working memory is shown to come from visual masking and attentional blink paradigms, and from the studies of implicit working memory. It is concluded that more research is needed to explicate the relationship between consciousness and working memory. Future research directions regarding the relationship between consciousness and working memory are discussed. Copyright © 2017 Elsevier Inc. All rights reserved.

  2. Adolescent suicide prevention. Current research and social policy implications.

    Science.gov (United States)

    Garland, A F; Zigler, E

    1993-02-01

    The rate of adolescent suicide has increased dramatically in the past few decades, prompting several interventions to curb the increase. Unfortunately, many of the intervention efforts have not benefited from current research findings because the communication between researchers and those who develop the interventions is inadequate. Of specific concern are the increasingly popular curriculum-based suicide prevention programs, which have not demonstrated effectiveness and may contain potentially deleterious components. This article reviews the current epidemiological research in adolescent suicide and suggests how this knowledge could be used more effectively to reduce the rate of adolescent suicide. Recommendations include support for integrated primary prevention efforts; suicide prevention education for professionals; education and policies on firearm management; education for the media about adolescent suicide; more efficient identification and treatment of at-risk youth, including those exposed to suicidal behavior; crisis intervention; and treatment for suicide attempters.

  3. Current research in Canada on biological effects of ionizing radiation

    International Nuclear Information System (INIS)

    Marko, A.M.

    1980-05-01

    A survey of current research in Canada on the biological effects of ionizing radiation has been compiled. The list of projects has been classified according to structure (organizational state of the test system) as well as according to the type of effects. Using several assumptions, ballpark estimates of expenditures on these activities have been made. Agencies funding these research activities have been tabulated and the break-down of research in government laboratories and in academic institutions has been designated. Wherever possible, comparisons have been made outlining differences or similarities that exist between the United States and Canada concerning biological radiation research. It has been concluded that relevant research in this area in Canada is inadequate. Wherever possible, strengths and weaknesses in radiation biology programs have been indicated. The most promising course for Canada to follow is to support adequately fundamental studies of the biological effects of radiation. (auth)

  4. Establishing a research agenda for scientific and technical information (STI) - Focus on the user

    Science.gov (United States)

    Pinelli, Thomas E.

    1992-01-01

    This report addresses the relationship between library science and information science theory and practice, between the development of conceptual understanding, and the practical competence of information professionals. Consideration is given to the concept of research, linking theory with practice, and the reality of theory based practice. Attention is given to the need for research and research priorities, focus on the user and information-seeking behavior, and a user-oriented research agenda for STI.

  5. Establishing a research agenda for Scientific and Technical Information (STI): Focus on the user

    Science.gov (United States)

    Pinelli, Thomas E.

    1992-01-01

    This report addresses the relationship between library science and information science theory and practice, between the development of conceptual understanding, and the practical competence of information professionals. Consideration is given to the concept of research, linking theory with practice, and the reality of theory based practice. Attention is given to the need for research and research priorities, focus on the user and information-seeking behavior, and a user-oriented research agenda for STI.

  6. Planning focus group interviews with asylum seekers: Factors related to the researcher, interpreter and asylum seekers.

    Science.gov (United States)

    Eklöf, Niina; Hupli, Maija; Leino-Kilpi, Helena

    2017-10-01

    The aim of this article was to discuss factors related to the researcher, interpreter and asylum seekers when planning focus group interviews with asylum seekers. Focus group interview is one of the basic data collection methods in descriptive nursing and health research. It has been used in multicultural research, allowing an opportunity to participate without literacy and to have linguistic and cultural support from other participants. Asylum seekers form a specific, vulnerable group, and the growing number of asylum seekers increases the need for research related to them. A culturally, methodologically and ethically high-quality focus group interview is based on the researcher's special knowledge and skills, acknowledgement of asylum seekers as both individuals and part of cultural and communal groups, and careful planning of the interpreter's role during the interviews. © 2017 John Wiley & Sons Ltd.

  7. Magnetic electron focusing and tuning of the electron current with a pn-junction

    Energy Technology Data Exchange (ETDEWEB)

    Milovanović, S. P., E-mail: slavisa.milovanovic@uantwerpen.be; Ramezani Masir, M., E-mail: mrmphys@gmail.com; Peeters, F. M., E-mail: francois.peeters@uantwerpen.be [Departement Fysica, Universiteit Antwerpen, Groenenborgerlaan 171, B-2020 Antwerpen (Belgium)

    2014-01-28

    Transverse magnetic focusing properties of graphene using a ballistic four terminal structure are investigated. The electric response is obtained using the semiclassical billiard model. The transmission exhibits pronounced peaks as a consequence of skipping orbits at the edge of the structure. When we add a pn-junction between the two probes, snake states along the pn-interface appear. Injected electrons are guided by the pn-interface to one of the leads depending on the value of the applied magnetic field. Oscillations in the resistance are found depending on the amount of particles that end up in each lead.

  8. Current state of research base improvement relating to decommissioning

    International Nuclear Information System (INIS)

    Kawamura, Hiroshi

    2015-01-01

    'Nuclear Damage Compensation and Decommissioning Facilitation Corporation (NDF)' is responsible for the strategic planning and research and development planning for the important issues such as fuel debris removal and waste management, and for support for the progress management of important issues. The research and development are conducted by 'International Research Institute for Decommissioning (IRID)' and 'Japan Atomic Energy Agency (JAEA).' In the medium- and long-term roadmap, it is described that 'as for the facilities JAEA is improving, application to the decommissioning of Fukushima Daiichi Nuclear Power Station is the first choice, but depending on necessity, the linkage with Fukushima Innovation Coast plan is put into consideration.' In consideration of other backgrounds and with a focus on the contribution to regional industry creation, the research centers that can play the following functions are being developed. (1) Performance of bridging function as a 'place' to promote mutually beneficial university-industry collaborative creation, while sharing a wide variety of users and goals, (2) bridge between basic infrastructure research and social implementation as the demonstration test base, (3) bridge between the research and development of Japan and foreign countries using the world network of the research base, and (4) intensive promotion of demonstration experiments that are difficult for private agencies, and the formulation of robot testing standards. (A.O.)

  9. Symposium: Organizational Health Intervention Research: Current Empirical Developments

    DEFF Research Database (Denmark)

    Ipsen, Christine; Jenny, Gregor

    2014-01-01

    or networks of employees. The intervention process is designed to involve the most effective set of stakeholders (leaders, management, experts, co-workers) and connect them to an efficient network of change agents. For this, the current interventions offer models, handbooks and indicators that inform...... Health Index”. The study, conducted in Switzerland, shows that the index predicts sick leave, stress symptoms, work engagement and self-rated productivity. • The fourth contribution Torsten Holstad and his colleagues present their summative evaluation of a tailor-made training program focusing on health...

  10. Current Research and Development of Chemotherapeutic Agents for Melanoma

    Directory of Open Access Journals (Sweden)

    Kyaw Minn Hsan

    2010-04-01

    Full Text Available Cutaneous malignant melanoma is the most lethal form of skin cancer and an increasingly common disease worldwide. It remains one of the most treatment-refractory malignancies. The current treatment options for patients with metastatic melanoma are limited and in most cases non-curative. This review focuses on conventional chemotherapeutic drugs for melanoma treatment, by a single or combinational agent approach, but also summarizes some potential novel phytoagents discovered from dietary vegetables or traditional herbal medicines as alternative options or future medicine for melanoma prevention. We explore the mode of actions of these natural phytoagents against metastatic melanoma.

  11. Current advances in the treatment of Alzheimer's disease: focused on considerations targeting Aβ and tau

    Directory of Open Access Journals (Sweden)

    Hong-Qi Yang

    2012-10-01

    Full Text Available Abstract Alzheimer’s disease (AD is a neurodegenerative disorder that impairs mainly the memory and cognitive function in elderly. Extracellular beta amyloid deposition and intracellular tau hyperphosphorylation are the two pathological events that are thought to cause neuronal dysfunction in AD. Since the detailed mechanisms that underlie the pathogenesis of AD are still not clear, the current treatments are those drugs that can alleviate the symptoms of AD patients. Recent studies have indicated that these symptom-reliving drugs also have the ability of regulating amyloid precursor protein processing and tau phosphorylation. Thus the pharmacological mechanism of these drugs may be too simply-evaluated. This review summarizes the current status of AD therapy and some potential preclinical considerations that target beta amyloid and tau protein are also discussed.

  12. CURRENT APPROACHES FOR RESEARCH OF MULTIPLE SCLEROSIS BIOMARKERS

    Directory of Open Access Journals (Sweden)

    Kolyada T.I

    2016-12-01

    Full Text Available Current data concerning features of multiple sclerosis (MS etiology, pathogenesis, clinical course and treatment of disease indicate the necessity of personalized approach to the management of MS patients. These features are the variety of possible etiological factors and mechanisms that trigger the development of MS, different courses of disease, and significant differences in treatment efficiency. Phenotypic and pathogenetic heterogeneity of MS requires, on the one hand, the stratification of patients into groups with different treatment depending on a number of criteria including genetic characteristics, disease course, stage of the pathological process, and forms of the disease. On the other hand, it requires the use of modern methods for assessment of individual risk of developing MS, its early diagnosis, evaluation and prognosis of the disease course and the treatment efficiency. This approach is based on the identification and determination of biomarkers of MS including the use of systems biology technology platforms such as genomics, proteomics, metabolomics and bioinformatics. Research and practical use of biomarkers of MS in clinical and laboratory practice requires the use of a wide range of modern medical and biological, mathematical and physicochemical methods. The group of "classical" methods used to study MS biomarkers includes physicochemical and immunological methods aimed at the selection and identification of single molecular biomarkers, as well as methods of molecular genetic analysis. This group of methods includes ELISA, western blotting, isoelectric focusing, immunohistochemical methods, flow cytometry, spectrophotometric and nephelometric methods. These techniques make it possible to carry out both qualitative and quantitative assay of molecular biomarkers. The group of "classical methods" can also include methods based on polymerase chain reaction (including multiplex and allele-specific PCR and genome sequencing

  13. Focus on CSIR research in water resources: water and human health research in CSIR

    CSIR Research Space (South Africa)

    Genthe, Bettina

    2007-08-01

    Full Text Available The Water and Human Health team researches water related science to address the CSIR’s mandate, national priorities and to improve quality of life for all. The overall aim of the research is to achieve a sustainable balance between the use of water...

  14. [Bioethical Approach for Nursing Research -Focused on the Use of Research Ethics Committees].

    Science.gov (United States)

    Jeong, Ihn Sook

    2015-06-01

    This paper was written to introduce methods of using the research ethics committee (RES) from requesting the initial review to reporting the close-out for nursing researchers. General ethical principles were described by reviewing the 'Bioethics and Safety Act' and other related guidelines, and constructing some questions and answers. The results were composed of three parts; definition of RES, steps in using RES, and archiving. The 7 steps for using RES were; identifying whether the study needed to be reviewed, by the RES identifying whether the study could be exempted, requesting the initial review after preparing documents, requesting the re-review, requesting an amendment review, requesting a continuing review and reporting the close-out. Nursing researchers need to receive RES approval before starting nursing research involving human subjects. Nursing researchers are urged to use the steps reported in this paper to receive RES approval easily and quickly.

  15. Impression management and food intake. Current directions in research.

    Science.gov (United States)

    Vartanian, Lenny R

    2015-03-01

    This paper reviews recent research on consumption stereotypes (judgments of others based on what they eat) and impression management (modifying one's eating behavior in order to create a particular impression). A major recent focus in the literature has been on masculinity and meat eating, with research showing that meat is strongly associated with masculinity, and that individuals who follow a meat-based diet are perceived as more masculine than are individuals who follow a vegetarian diet. Although direct evidence for impression management through food intake remains sparse, a number of methodological approaches (including priming techniques and ecological valid assessments) are described that could be used in future research to identify the motives underlying people's eating behavior. Consumption stereotypes and impression management may be important influences on people's eating behavior, but the complexities of how, when, and for whom these factors influence food intake are still not well understood. Copyright © 2014 Elsevier Ltd. All rights reserved.

  16. Opening the "black box" of current creativity research

    DEFF Research Database (Denmark)

    Hoffmann Birk, Rasmus; Ernø, Steffen

    -2012. The sub-fields were chosen because of their prominence in psychological research and research on creativity. The articles were procured from the PsycINFO database, with selection criteria being that they must be peer-reviewed and empirical studies. Typical definitions of creativity were "novelty plus...... value" or none at all. Creativity was mostly measured with different types of divergent thinking tests. There appears to be a lack of deeper theoretical and methodological discussions of creativity in the literature, which creates a disconnection between definitions, methodologies and the interpretation...... of empirical findings in regards to creativity as a phenomenon. Creativity itself thus becomes a "black box", rarely opened to investigation. Creativity research could therefore benefit from a more sustained relfection over its theoretical and methodological underpinnings as well as shifting its focus towards...

  17. Current status of research and development at Japan Atomic Energy Agency

    International Nuclear Information System (INIS)

    2015-01-01

    This paper introduces the current state and future prospects of Japan Atomic Energy Agency, with a focus on the main achievements of the research and development as of November FY2014. The items of research and development are as follows; (1) research and development related to measures for the accident of Fukushima Daiichi Nuclear Power Station, (2) technological assistance for ensuring safety in the research and development and utilization of nuclear power, (3) research science related to the research and development and utilization of nuclear power, (4) practical application of FBR cycle, (5) technological development related to back-end measures, (6) research and development of technological system to retrieve nuclear fusion energy, and (7) common projects (computational science / engineering / research, technological development and policy assistance on nuclear non-proliferation and nuclear security, and various activities such as dissemination of the fruits of research and development, human resource development, and technological cooperation). (A.O.)

  18. [New Paradigms? Current Trends within National and International Psychotherapy Research].

    Science.gov (United States)

    Strauß, Bernhard

    2015-09-01

    This article is devoted to the question which paradigms currently determine psychotherapy and psychotherapy research, and if there are indicators of paradigm changes in this field. The question of the efficacy and effectiveness (including the effectiveness of a transfer of psychotherapeutic knowledge to service) is specifically focussed as well as the question of the central therapeutic factors and the significance of the person of the therapist. It is argued that there are really some signals of a paradigm switch, with a turn away from controlled outcome research, representing only a minor part of patients in need of psychotherapy, towards a more specific process oriented research, also considering differential effects of the therapist. The most prominent indicator of a paradigm change is reflected by an increasing influence of patient oriented psychotherapy research which - consequently - should also be supported by the insurances as well as the funding organisations. © Georg Thieme Verlag KG Stuttgart · New York.

  19. Research in nuclear chemistry: current status and future perspectives

    International Nuclear Information System (INIS)

    Reddy, A.V.R.

    2007-01-01

    Research in nuclear chemistry has seen a huge growth over the last few decades. The large umbrella of nuclear chemistry includes several research areas such as nuclear fission, reactions, spectroscopy, nuclear probes and nuclear analytical techniques. Currently, nuclear chemistry research has extended its horizon into various applications like nuclear medicine, isotopes for understanding physico chemical processes, and addressing environmental and biomedical problems. Tremendous efforts are going on for synthesizing new elements (isotopes), isolating physically or chemically wherever possible and investigating their properties. Theses studies are useful to understand nuclear and chemical properties at extreme ends of instability. In addition, nuclear chemists are making substantial contribution to astrophysics and other related areas. During this talk, a few of the contributions made by nuclear chemistry group of BARC will be discussed and possible future areas of research will be enumerated. (author)

  20. Implications for Focusing Research in Career and Technical Education and Workforce Development

    Science.gov (United States)

    Lambeth, Jeanea M.; Joerger, Richard M.; Elliot, Jack

    2009-01-01

    Education and educational research is shaped by philosophy, psychology, practice, and ever changing educational policies. Previous studies have expressed a need for a relevant and focused research agenda for career and technical education (CTE), workforce development education and career and technical education. A need for a relevant and timely…

  1. Linking Teacher Evaluation to Professional Development: Focusing on Improving Teaching and Learning. Research & Policy Brief

    Science.gov (United States)

    Goe, Laura; Biggers, Kietha; Croft, Andrew

    2012-01-01

    Recently, teacher evaluation has become a major focus in educational policy debates and research efforts. This increased attention to teacher evaluation has raised questions about the relationship between evaluation and student outcomes. Rivkin, Hanushek, and Kain (2005) and others have demonstrated with value-added research that there are…

  2. Current National Approach to Healthcare ICT Standardization: Focus on Progress in New Zealand.

    Science.gov (United States)

    Park, Young-Taek; Atalag, Koray

    2015-07-01

    Many countries try to efficiently deliver high quality healthcare services at lower and manageable costs where healthcare information and communication technologies (ICT) standardisation may play an important role. New Zealand provides a good model of healthcare ICT standardisation. The purpose of this study was to review the current healthcare ICT standardisation and progress in New Zealand. This study reviewed the reports regarding the healthcare ICT standardisation in New Zealand. We also investigated relevant websites related with the healthcare ICT standards, most of which were run by the government. Then, we summarised the governance structure, standardisation processes, and their output regarding the current healthcare ICT standards status of New Zealand. New Zealand government bodies have established a set of healthcare ICT standards and clear guidelines and procedures for healthcare ICT standardisation. Government has actively participated in various enactments of healthcare ICT standards from the inception of ideas to their eventual retirement. Great achievements in eHealth have already been realized, and various standards are currently utilised at all levels of healthcare regionally and nationally. Standard clinical terminologies, such as International Classification of Diseases (ICD) and Systematized Nomenclature of Medicine - Clinical Terms (SNOMED-CT) have been adopted and Health Level Seven (HL7) standards are actively used in health information exchanges. The government to New Zealand has well organised ICT institutions, guidelines, and regulations, as well as various programs, such as e-Medications and integrated care services. Local district health boards directly running hospitals have effectively adopted various new ICT standards. They might already be benefiting from improved efficiency resulting from healthcare ICT standardisation.

  3. The Development and Current State of Translation Process Research

    DEFF Research Database (Denmark)

    Lykke Jakobsen, Arnt

    2014-01-01

    The development and current state of translation process research ch Arnt Lykke Jakobsen Copenhagen Business School lInterest in process-oriented translation studies has been intense for the past almost half a century. Translation process research (TPR) is the label we have used to refer to a spe...... itself, into regions like cognitive psychology, psycho- and neurolinguistics, and neuroscience, where the interest in what goes on in our heads is also very strong.......The development and current state of translation process research ch Arnt Lykke Jakobsen Copenhagen Business School lInterest in process-oriented translation studies has been intense for the past almost half a century. Translation process research (TPR) is the label we have used to refer...... which simultaneously tracks the translator’s eye movements across a screen displaying both a source text and the translator’s emerging translation. This research method was developed as a means of qualifying and strengthening translation process hypotheses based on verbal reports by providing additional...

  4. Water management: Current and future challenges and research directions

    Science.gov (United States)

    Cosgrove, William J.; Loucks, Daniel P.

    2015-06-01

    Water distinguishes our planet compared to all the others we know about. While the global supply of available freshwater is more than adequate to meet all current and foreseeable water demands, its spatial and temporal distributions are not. There are many regions where our freshwater resources are inadequate to meet domestic, economic development and environmental needs. In such regions, the lack of adequate clean water to meet human drinking water and sanitation needs is indeed a constraint on human health and productivity and hence on economic development as well as on the maintenance of a clean environment and healthy ecosystems. All of us involved in research must find ways to remove these constraints. We face multiple challenges in doing that, especially given a changing and uncertain future climate, and a rapidly growing population that is driving increased social and economic development, globalization, and urbanization. How best to meet these challenges requires research in all aspects of water management. Since 1965, the journal Water Resources Research has played an important role in reporting and disseminating current research related to managing the quantity and quality and cost of this resource. This paper identifies the issues facing water managers today and future research needed to better inform those who strive to create a more sustainable and desirable future.

  5. Current concepts of metabolic abnormalities in HIV patients: focus on lipodystrophy.

    Science.gov (United States)

    Kolter, Donald P

    2003-12-01

    HIV infection is associated with a number of metabolic abnormalities, including lipodystrophy, a difficult-to-define disorder whose characteristics include hyperlipidemia, insulin resistance, and fat redistribution. Current data suggest that lipodystrophy is caused by multiple factors. Dual-nucleoside reverse transcriptase inhibitor therapy combined with protease inhibitor therapy has been shown to increase the risk of metabolic abnormalities, but susceptibility independent of drug effects has also been shown. While many of the treatments for the broad range of signs and symptoms of lipodystrophy bring about improvements in patient status, none have been demonstrated to bring about a return to baseline levels.

  6. Trends in Mediation Analysis in Nursing Research: Improving Current Practice.

    Science.gov (United States)

    Hertzog, Melody

    2018-06-01

    The purpose of this study was to describe common approaches used by nursing researchers to test mediation models and evaluate them within the context of current methodological advances. MEDLINE was used to locate studies testing a mediation model and published from 2004 to 2015 in nursing journals. Design (experimental/correlation, cross-sectional/longitudinal, model complexity) and analysis (method, inclusion of test of mediated effect, violations/discussion of assumptions, sample size/power) characteristics were coded for 456 studies. General trends were identified using descriptive statistics. Consistent with findings of reviews in other disciplines, evidence was found that nursing researchers may not be aware of the strong assumptions and serious limitations of their analyses. Suggestions for strengthening the rigor of such studies and an overview of current methods for testing more complex models, including longitudinal mediation processes, are presented.

  7. Process research on Emotionally Focused Therapy (EFT) for couples: linking theory to practice.

    Science.gov (United States)

    Greenman, Paul S; Johnson, Susan M

    2013-03-01

    The focus of this article is on the link among theory, process, and outcome in the practice of Emotionally Focused Therapy (EFT) for couples. We describe the EFT model of change and the EFT perspective on adult love as the reflection of underlying attachment processes. We outline the manner in which theory and research inform EFT interventions. This leads into a detailed review of the literature on the processes of change in EFT. We highlight the client responses and therapist operations that have emerged from process research and their relation to treatment outcomes. We discuss the implications of this body of research for clinical practice and training. © FPI, Inc.

  8. Current trends in stroke rehabilitation. A review with focus on brain plasticity.

    Science.gov (United States)

    Johansson, B B

    2011-03-01

    Current understanding of brain plasticity has lead to new approaches in ischemic stroke rehabilitation. Stroke units that combine good medical and nursing care with task-oriented intense training in an environment that provides confidence, stimulation and motivation significantly improve outcome. Repetitive trans-cranial magnetic stimulation (rTMS), and trans-cranial direct current stimulation (tDCS) are applied in rehabilitation of motor function. The long-term effect, optimal way of stimulation and possibly efficacy in cognitive rehabilitation need evaluation. Methods based on multisensory integration of motor, cognitive, and perceptual processes including action observation, mental training, and virtual reality are being tested. Different approaches of intensive aphasia training are described. Recent data on intensive melodic intonation therapy indicate that even patients with very severe non-fluent aphasia can regain speech through homotopic white matter tract plasticity. Music therapy is applied in motor and cognitive rehabilitation. To avoid the confounding effect of spontaneous improvement, most trials are preformed ≥3 months post stroke. Randomized controlled trials starting earlier after strokes are needed. More attention should be given to stroke heterogeneity, cognitive rehabilitation, and social adjustment and to genetic differences, including the role of BDNF polymorphism in brain plasticity. © 2010 John Wiley & Sons A/S.

  9. Current robotic curricula for surgery residents: A need for additional cognitive and psychomotor focus.

    Science.gov (United States)

    Green, Courtney A; Chern, Hueylan; O'Sullivan, Patricia S

    2018-02-01

    Current robot surgery curricula developed by industry were designed for expert surgeons. We sought to identify the robotic curricula that currently exist in general surgery residencies and describe their components. We identified 12 residency programs with robotic curricula. Using a structured coding form to identify themes including sequence, duration, emphasis and assessment, we generated a descriptive summary. Curricula followed a similar sequence: learners started with online modules and simulation exercises, followed by bedside experience during R2-R3 training years, and then operative opportunities on the console in the final years of training. Consistent portions of the curricula reflect a device-dependent training paradigm; they defined the sequence of instruction. Most curricula lacked specifics on duration and content of training activities. None clearly described cognitive or psychomotor skills needed by residents and none required a proficiency assessment before graduation. Resident-specific robotic curricula remain grounded in initial industrial efforts to train experienced surgeons, are non-specific regarding the type and nature of hands on experience, and do not include discussion of operative technique and surgical concepts. Copyright © 2017 Elsevier Inc. All rights reserved.

  10. Monaco - IAEA [Marine Radioecology. Current Research and Future Scope

    International Nuclear Information System (INIS)

    Joseph, J.; Chipman, W.A.; Fukai, R.; Duursma, E.K.

    1967-01-01

    Present and future research: Transport of radionuclides by turbulent diffusion processes. The radionuclides which are introduced into the sea will be dispersed by turbulent processes caused by currents, tides, waves and so forth. One of the most urgent needs for estimation of radionuclide behaviour in the sea is to study such diffusion processes and to interpret and describe the results so that they can be used for prediction of similar processes affecting the dispersion of radioactive materials in marine environments

  11. Current Studies on Crisis Response Communication:Focus on Crisis Communication Theories in the United States

    OpenAIRE

    平澤 敦

    2017-01-01

    Researchers have shown an increased interest in crisis communication as well as crisis management. Crisis communication became an established corporate discipline in the last 20 years. Because of the recent rash of corporate (organizational) scandals, natural disasters and so on, importance of crisis communication (management) attracts much more attention than the past.Crisis communication is used to help governments and companies organizations to respond to and recover from a crisis. Crisis ...

  12. Waste management in the Irkutsk Region, Siberia, Russia: Environmental assessment of current practice focusing on landfilling

    DEFF Research Database (Denmark)

    Starostina, Vlada; Damgaard, Anders; Rechberger, Helmut

    2014-01-01

    The municipal waste management system of the region of Irkutsk is described and a life cycle assessment (LCA) performed to assess the environmental performance of the system. Annually about 500 000 tons of waste are managed. The waste originates from three sources: household waste (27%), commercial...... waste (23%) and office & institutional waste (44%). Other waste of unknown composition constitutes 6%. Only 3% of the waste is recycled; 97% of the municipal waste is disposed of at the old Alexandrovsky landfill. The environmental impact from the current system is dominated by the landfill, which has...... no gas or leachate collection system. The global warming contribution is due to the emission of methane of the order of 420 000 tons CO2-equivalents per year. Collection and transport of the waste are insignificant compared with impacts from the landfill. As the old landfill runs out of capacity in a few...

  13. On 2D electron cloud dynamics in high-current plasma lens for ion beam focusing

    International Nuclear Information System (INIS)

    Goncharov, A. A.; Litovko, I. V.; Onishchenko, I. N.; Zadorozhny, V. F.

    1997-01-01

    In this paper we are dealing with the appear the stable existence and dynamics of 2-D electron vortical structures in crossed electric and magnetic fields. The collective interactions in which the electron motion is nonlinear and ion motion is linear, is concerned. By using of the kinetic equation and the catastrophe theory approach we deduce an origin of the vortical structures. The nonlinear differential equation for the electric potential in a hydrodynamical approximation is obtained. It describes a drift motion of the electrons in oscillating electric fields of the high-current plasma lens(PL), arising due to presence the principal unremoval radical gradient of the axical component of the magnetic field. It was shown that the considered equations have contained the solutions in the form of the single vortical structures. The stability of the structures are given

  14. Effects of Focus of Accounting Research on the Quality of Accounting Education in Malaysian Universities

    OpenAIRE

    Kabiru Isa Dandago; Nor Azlina Binti Shaari

    2013-01-01

    This paper reviews the impact of focus of research in accounting on the quality of accounting education in Malaysian Universities. Research in accounting is very important in Malaysian Universities, in particular, and the Malaysian tertiary educational institutions, in general, and it is expected that academic research in accounting would improve the quality of accounting education in the country. The study is mainly a literature review type, with some informal interviews conducted for confir...

  15. Happiness and Well-Being: Shifting the Focus of the Current Debate

    DEFF Research Database (Denmark)

    Rodogno, Raffaele

    2014-01-01

    The point of departure of this paper is the recently emphasised distinction between psychological theories of happiness, on the one hand, and normative theories of well-being, on the other. With this distinction in mind, I examine three possible kinds of relation that might exist between (psychol......The point of departure of this paper is the recently emphasised distinction between psychological theories of happiness, on the one hand, and normative theories of well-being, on the other. With this distinction in mind, I examine three possible kinds of relation that might exist between...... (psychological) happiness and (normative) well-being; to wit, happiness may be understood as playing a central part in (1) a formal theory of well-being, (2) a substantive theory of well-being or (3) as an indicator for well-being. I note that, in the relevant literature, happiness is mostly discussed in terms...... of either (1) or (2). In this paper, I attempt to motivate a shift of focus away from such accounts of happiness and towards (3), i.e. its epistemic role. When examined in connection to (normative) well-being, (psychological states of) happiness and unhappiness should be understood as psychological states...

  16. Focused Ultrasound for Essential Tremor: Review of the Evidence and Discussion of Current Hurdles

    Directory of Open Access Journals (Sweden)

    Mohammad Rohani

    2017-05-01

    Full Text Available Background. While there is no breakthrough progress in the medical treatment of essential tremor (ET, in the past decades several remarkable achievements happened in the surgical field, such as radiofrequency thalamotomy, thalamic deep brain stimulation and gamma knife thalamotomy. The most recent advance in this area is magnetic resonance-guided focused ultrasound (MRgFUS. Methods. Purpose of this review is to discuss the new developments and trials of MRgFUS in the treatment of ET and other tremor disorders. Results. MRgFUS is an incision-less surgery performed without anesthesia and ionizing radiation (no risk of cumulative dose and delayed side effects. Studies have shown the safety and effectiveness of unilateral MRgFUS-thalamotomy in the treatment of ET. It has been successfully used in few patients with Parkinson's disease-related tremor and fewer patients with Fragile X-associated Tremor/Ataxia Syndrome. Safety and long-term effects of the procedure are still unclear, as temporary and permanent adverse events have been reported as well as reoccurrence of tremor. Discussion. MRgFUS is a promising new surgical approach with still a number of unknowns and unsolved issues. It represents a valuable option particularly for patients who refused or could not be candidate for other procedures, deep brain stimulation in particular. 

  17. Very high-current propagation in the ion-focused to collision-dominated regime

    International Nuclear Information System (INIS)

    Sanford, T.W.L.; Welch, D.R.; Mock, R.C.

    1994-01-01

    Measurements and analysis show that the 13 TW, Hermes-III [J. J. Ramirez et al., Digest of Technical Papers, 6th IEEE Pulsed Power Conference (Institute of Electrical and Electronic Engineers, New York, 1987), p. 294], pulsed, electron beam has two windows of stable transport in long drift cells filled with N 2 gas terminated by a bremsstrahlung producing target: a low-pressure window (between ∼1 and ∼100 mTorr) that is dominated by propagation in the semicollisionless ion-focused regime (IFR), and a high-pressure window (between ∼1 and ∼100 Torr) that is dominated by propagation in the resistive collisional regime. In the transition region between the two windows, beam plasma--electron instabilities significantly disrupt propagation. Propagation in both regimes (the IFR at early time and the collisional at later time) is observed from ∼5 to ∼100 mTorr, which produces two distinct bremsstrahlung pulses from the single injected beam pulse. As the pressure increases, two-stream instabilities terminate IFR propagation and the associated bremsstrahlung pulse earlier and earlier in time. Above 5 mTorr, the instability is sufficiently quenched by gas collisions that propagation in the collisional regime back in the beam body occurs, leading to a second propagation and associated bremsstrahlung pulse. Above 200 mTorr, the gas breaks down too rapidly for a significant IFR pulse to form, and for higher pressures only a single pulse in the collisional regime is propagated. Reasonable stability in the collisional regime is not achieved until pressures exceed 1 Torr

  18. Current status of oral health research in Africa: an overview.

    Science.gov (United States)

    Kanoute, Aïda; Faye, Daouda; Bourgeois, Denis

    2012-12-01

    Research in oral health contributes effectively to decisions and strategies aimed at improving the oral health of populations. Further contributions to enhance current knowledge of oral health in Africa are required. The principal objective of this study was to produce an analysis of oral health research published from different subregions of Africa and to estimate bilateral and multilateral international cooperation in oral health research during the period 2005-2010. The PubMed database was searched for published articles on topics related to oral health in Africa. A total of 935 oral health-related articles were retrieved during April and May 2011. Publications emanating from Nigeria and South Africa accounted for a striking 68% of all oral health-related material published from Africa during the study period. Researchers from 30 different countries had participated in collaboration on at least one published article. A total of 262 journals had published at least one item examining oral health in Africa, but only 29 journals had published more than seven articles. These 29 journals accounted for 66% of all published material and induced non-African reviews (26%) and African reviews (40%). This study shows strong variation among countries in the production of articles on oral health whereby rich countries produce greater quantities of published research and poorer nations more frequently develop research partnerships with other countries. © 2012 FDI World Dental Federation.

  19. Current electroconvulsive therapy practice and research in the geriatric population

    Science.gov (United States)

    Kerner, Nancy; Prudic, Joan

    2014-01-01

    SUMMARY Electroconvulsive therapy (ECT) is utilized worldwide for various severe and treatment-resistant psychiatric disorders. Research studies have shown that ECT is the most effective and rapid treatment available for elderly patients with depression, bipolar disorder and psychosis. For patients who suffer from intractable catatonia and neuroleptic malignant syndrome, ECT can be life saving. For elderly patients who cannot tolerate or respond poorly to medications and who are at a high risk for drug-induced toxicity or toxic drug interactions, ECT is the safest treatment option. Organic causes are frequently associated with late-life onset of neuropsychiatric conditions, such as parkinsonism, dementia and stroke. ECT has proven to be efficacious even when these conditions are present. During the next decade, research studies should focus on the use of ECT as a synergistic therapy, to enhance other biological and psychological treatments, and prevent symptom relapse and recurrence. PMID:24778709

  20. Challenges to socio-economic research in a changing society - with a special focus on Greenland

    DEFF Research Database (Denmark)

    Poppel, Birger; Rasmussen, Rasmus Ole; Winther, Gorm

    2005-01-01

    The process of changes in Arctic societies has been from a cultural order to an economic order, and from a closed society based on barter and subsistence to a society based on economic exchange through monetary means. Consequently, understanding the currents of change requires a definite focus...

  1. The Alsep Data Recovery Focus Group of NASA's Solar System Exploration Research Virtual Institute

    Science.gov (United States)

    Nagihara, S.; Lewis, L. R.; Nakamura, Y.; Williams, D. R.; Taylor, P. T.; Hills, H. K.; Kiefer, W. S.; Neal, C. R.; Schmidt, G. K.

    2014-12-01

    Astronauts on Apollo 12, 14, 15, 16, and 17 deployed instruments on the Moon for 14 geophysical experiments (passive & active seismic, heat flow, magnetics, etc.) from 1969 to 1972. These instruments were called Apollo Lunar Surface Experiments Packages (ALSEPs). ALSEPs kept transmitting data to the Earth until September 1977. When the observation program ended in 1977, a large portion of these data were not delivered to the National Space Science Data Center for permanent archive. In 2010, for the purpose of searching, recovering, preserving, and analyzing the data that were not previously archived, NASA's then Lunar Science Institute formed the ALSEP Data Recovery Focus Group. The group consists of current lunar researchers and those involved in the ALSEP design and data analysis in the 1960s and 1970s. Among the data not previously archived were the 5000+ 7-track open-reel tapes that recorded raw data from all the ALSEP instruments from April 1973 to February 1976 ('ARCSAV tapes'). These tapes went missing in the decades after Apollo. One of the major achievements of the group so far is that we have found 450 ARCSAV tapes from April to June 1975 and that we are extracting data from them. There are 3 other major achievements by the group. First, we have established a web portal at the Lunar and Planetary Institute, where ~700 ALSEP-related documents, totaling ~40,000 pages, have been digitally scanned and cataloged. Researchers can search and download these documents at www.lpi.usra.edu/ lunar/ALSEP/. Second, we have been retrieving notes and reports left behind by the now deceased/retired ALSEP investigators at their home institutions. Third, we have been re-analyzing the ALSEP data using the information from the recently recovered metadata (instrument calibration data, operation logs, etc.). Efforts are ongoing to get these data permanently archived in the Planetary Data System (PDS).

  2. Pediatric Renal Transplantation: Focus on Current Transition Care and Proposal of the "RISE to Transition" Protocol.

    Science.gov (United States)

    Raina, Rupesh; Wang, Joseph; Krishnappa, Vinod; Ferris, Maria

    2018-01-16

    The transition from pediatric to adult medical services is an important time in the life of an adolescent or young adult with a renal transplant. Failure of proper transition can lead to medical non-adherence and subsequent loss of graft and/or return to dialysis. The aim of this study was to conduct a systematic review and survey to assess the challenges and existing practices in transition of renal transplant recipient children to adult services, and to develop a transition protocol. We conducted a literature review and performed a survey of pediatric nephrologists across the United States to examine the current state of transition care. A structured transition protocol was developed based on these results. Our literature review revealed that a transition program has a positive impact on decline in renal function and acute rejection episodes, and may improve long-term graft outcomes in pediatric kidney transplant patients. With a response rate of 40% (60/150) from nephrologists in 56% (49/87) of centers, our survey shows inconsistent use of validated tools despite their availability, inefficient communication between teams, and lack of use of dedicated clinics. To address these issues, we developed the "RISE to Transition" protocol, which relies on 4 competency areas: Recognition, Insight, Self-reliance, and Establishment of healthy habits. The transition program decreases acute graft rejection episodes, and the main challenges in transition care are the communication gap between health care providers and inconsistent use of transition tools. Our RISE to transition protocol incorporates transition tools, defines personnel, and aims to improve communication between teams.

  3. Current status and future direction of nanomedicine: Focus on advanced biological and medical applications

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Eun Mi; Jeong, Hwan Jeong [Dept. of Nuclear Medicine, Molecular Imaging and Therapeutic Medicine Research Center, Cyclotron Research Center, Institute for Medical Science, Chonbuk National University Medical School and Hospital, Jeonju (Korea, Republic of)

    2017-06-15

    Nanotechnology is the engineering and manipulation of materials and devices with sizes in the nanometer range. Colloidal gold, iron oxide nanoparticles and quantum dot semiconductor nanocrystals are examples of nanoparticles, with sizes generally ranging from 1 to 20 nm. These nanotechnologies have been researched tremendously in the last decade and this has led to a new area of “nanomedicine” which is the application of nanotechnology to human health-care for diagnosis, monitoring, treatment, prediction and prevention of diseases. Recently progress has been made in overcoming some of the difficulties in the human use of nanomedicines. In the mid-1990s, Doxil was approved by the FDA, and now various nanoconstructs are on the market and in clinical trials. However, there are many obstacles in the human application of nanomaterials. For translation to clinical use, a detailed understanding is needed of the chemical and physical properties of particles and their pharmacokinetic behavior in the body, including their biodistribution, toxicity, and biocompatibility. In this review, we provide a broad introduction to nanomedicines and discuss the preclinical and clinical trials in which they have been evaluated.

  4. Current status and future direction of nanomedicine: Focus on advanced biological and medical applications

    International Nuclear Information System (INIS)

    Kim, Eun Mi; Jeong, Hwan Jeong

    2017-01-01

    Nanotechnology is the engineering and manipulation of materials and devices with sizes in the nanometer range. Colloidal gold, iron oxide nanoparticles and quantum dot semiconductor nanocrystals are examples of nanoparticles, with sizes generally ranging from 1 to 20 nm. These nanotechnologies have been researched tremendously in the last decade and this has led to a new area of “nanomedicine” which is the application of nanotechnology to human health-care for diagnosis, monitoring, treatment, prediction and prevention of diseases. Recently progress has been made in overcoming some of the difficulties in the human use of nanomedicines. In the mid-1990s, Doxil was approved by the FDA, and now various nanoconstructs are on the market and in clinical trials. However, there are many obstacles in the human application of nanomaterials. For translation to clinical use, a detailed understanding is needed of the chemical and physical properties of particles and their pharmacokinetic behavior in the body, including their biodistribution, toxicity, and biocompatibility. In this review, we provide a broad introduction to nanomedicines and discuss the preclinical and clinical trials in which they have been evaluated

  5. Lin Receives 2010 Natural Hazards Focus Group Award for Graduate Research

    Science.gov (United States)

    2010-11-01

    Ning Lin has been awarded the Natural Hazards Focus Group Award for Graduate Research, given annually to a recent Ph.D. recipient for outstanding contributions to natural hazards research. Lin's thesis is entitled “Multi-hazard risk analysis related to hurricanes.” She is scheduled to present an invited talk in the Extreme Natural Events: Modeling, Prediction, and Mitigation session (NH20) during the 2010 AGU Fall Meeting, held 13-17 December in San Francisco, Calif. Lin will be formally presented with the award at the Natural Hazards focus group reception on 14 December 2010.

  6. Current safety practices in nano-research laboratories in China.

    Science.gov (United States)

    Zhang, Can; Zhang, Jing; Wang, Guoyu

    2014-06-01

    China has become a key player in the global nanotechnology field, however, no surveys have specifically examined safety practices in the Chinese nano-laboratories in depth. This study reports results of a survey of 300 professionals who work in research laboratories that handle nanomaterials in China. We recruited participants at three major nano-research laboratories (which carry out research in diverse fields such as chemistry, material science, and biology) and the nano-chemistry session of the national meeting of the Chinese Chemical Society. Results show that almost all nano-research laboratories surveyed had general safety regulations, whereas less than one third of respondents reported having nanospecific safety rules. General safety measures were in place in most surveyed nano-research laboratories, while nanospecific protective measures existed or were implemented less frequently. Several factors reported from the scientific literature including nanotoxicology knowledge gaps, technical limitations on estimating nano-exposure, and the lack of nano-occupational safety legislation may contribute to the current state of affairs. With these factors in mind and embracing the precautionary principle, we suggest strengthening or providing nanosafety training (including raising risk awareness) and establishing nanosafety guidelines in China, to better protect personnel in the nano-workplace.

  7. Helical system. History and current state of helical research

    International Nuclear Information System (INIS)

    Yokoyama, Masayuki

    2017-01-01

    This paper described the following: (1) history of nuclear fusion research of Japan's original heliotron method, (2) worldwide development of nuclear fusion research based on helical system such as stellarator, and (3) worldwide meaning of large helical device (LHD) aiming to demonstrate the steady-state performance of heliotron type in the parameter area extrapolable to the core plasma, and research results of LHD. LHD demonstrated that the helical system is excellent in steady operation performance at the world's most advanced level. In an experiment using deuterium gas in 2017, LHD achieved to reach 120 million degrees of ion temperature, which is one index of nuclear fusion condition, demonstrated the realization of high-performance plasma capable of extrapolating to future nuclear fusion reactors, and established the foundation for full-scale research toward the realization of nuclear fusion reactor. Besides experimental research, this paper also described the helical-type stationary nuclear fusion prototype reactor, FFHR-d1, which was based on progress of large-scale simulation at the world's most advanced level. A large-scale superconducting stellarator experimental device, W7-X, with the same scale as LHD, started experiment in December 2015, whose current state is also touched on here. (A.O.)

  8. Gender relations and health research: a review of current practices

    Directory of Open Access Journals (Sweden)

    Bottorff Joan L

    2011-12-01

    Full Text Available Abstract Introduction The importance of gender in understanding health practices and illness experiences is increasingly recognized, and key to this work is a better understanding of the application of gender relations. The influence of masculinities and femininities, and the interplay within and between them manifests within relations and interactions among couples, family members and peers to influence health behaviours and outcomes. Methods To explore how conceptualizations of gender relations have been integrated in health research a scoping review of the existing literature was conducted. The key terms gender relations, gender interactions, relations gender, partner communication, femininities and masculinities were used to search online databases. Results Through analysis of this literature we identified two main ways gender relations were integrated in health research: a as emergent findings; and b as a basis for research design. In the latter, gender relations are included in conceptual frameworks, guide data collection and are used to direct data analysis. Conclusions Current uses of gender relations are typically positioned within intimate heterosexual couples whereby single narratives (i.e., either men or women are used to explore the influence and/or impact of intimate partner gender relations on health and illness issues. Recommendations for advancing gender relations and health research are discussed. This research has the potential to reduce gender inequities in health.

  9. Still Human: A Call for Increased Focus on Ethical Standards in Cadaver Research.

    Science.gov (United States)

    Bach, Michelle C

    2016-12-01

    Research on human cadavers is an important mechanism of scientific progress and comprises a large industry in the United States. However, despite its importance and influence, there is little ethical or regulatory oversight of cadaver-based research. This lack of transparency raises important ethical questions. Thus, this paper serves as a call for ethicists and regulators to pay increased attention to cadaver research. I argue that cadaver research ought to be considered a subset of human subjects research and held accountable to higher ethical standards. After describing current practices, I argue that oversight of cadaver research as a form of human subjects research is appropriate because cadaver research is similar to other types of human research, participants in cadaver research incur risks of harm, and a current lack of oversight has allowed the cadaver industry to entice research participation through ethically questionable practices. This paper urges greater dialogue among human subjects research ethicists and regulators about what constitutes appropriate protections for participants in cadaver research.

  10. Focusing on Cause or Cure?: Priorities and Stakeholder Presence in Childhood Psychiatry Research.

    Science.gov (United States)

    Milner, Lauren C; Cho, Mildred K

    2014-01-01

    Biomedical research is influenced by many factors, including the involvement of stakeholder groups invested in research outcomes. Stakeholder involvement in research efforts raise questions of justice as their specific interests and motivations play a role in directing research resources that ultimately produce knowledge shaping how different conditions (and affected individuals) are understood and treated by society. This issue is highly relevant to child psychiatry research where diagnostic criteria and treatment strategies are often controversial. Biological similarities and stakeholder differences between attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) provide an opportunity to explore this issue by comparing research foci and stakeholder involvement in these conditions. A subset of ADHD and ASD research articles published between 1970-2010 were randomly selected from the PubMed database and coded for research focus, funding source(s), and author-reported conflicts of interest (COIs). Chi-square analyses were performed to identify differences between and within ADHD and ASD research across time. The proportion of ADHD research dedicated to basic, description, and treatment research was roughly similar and remained stable over time, while ASD research showed a significant increase in basic research over the past decade. Government was the primary research funder for both conditions, but for-profit funders were a notable presence in ADHD research, while joint-funding efforts between non-profit and government funders were a notable presence in ASD research. Lastly, COIs were noted more frequently in ADHD than in ASD research. Our study shows significant differences in research foci and funding sources between the conditions, and identifies the specific involvement of for-profit and non-profit groups in ADHD and ASD, respectively. Our findings highlight the relationship between stakeholders outside the research community and

  11. Current Sandia programs and laboratory facilities for tritium research

    International Nuclear Information System (INIS)

    Swansiger, W.A.; West, L.A.

    1975-01-01

    Currently envisioned fusion reactor systems will contain substantial quantities of tritium. Strict control of the overall tritium inventory and environmental safety considerations require an accurate knowledge of the behavior of this isotope in the presence of Controlled Thermonuclear Reactor (CTR) materials. A 14,000 ft 2 laboratory for tritium research is currently under construction at Sandia Laboratories in Livermore. Details about the laboratory in general are provided. Results from studies of hydrogen isotope diffusion in surface-characterized metals will be presented. Details of two permeation systems (one for hydrogen and deuterium, the other for tritium) will be discussed. Data will also be presented concerning the gettering of hydrogen isotopes and application to CTR collector designs. (auth)

  12. Current ecological research towards completion criteria in Queensland

    Energy Technology Data Exchange (ETDEWEB)

    Grigg, A.; Mulligan, D.; Bellairs, S.; Harwood, M. [University of Queensland, St. Lucia, Qld. (Australia). Centre for Mined Land Rehabilitation

    1998-12-31

    There is a growing recognition of the need for criteria to determine when rehabilitation is successful or complete. Moreover, with the current emphasis on sustainability, criteria need to embrace a range of ecological attributes which in turn require an understanding of the ecosystems being created. This paper describes current research by the Centre for Mined Land Rehabilitation on ecosystem development at a number of operations throughout Queensland in the a bauxite, heavy mineral sands, gold and coal mining sectors. Case studies are presented which cover a number of ecological processes including nutrient cycling, vegetation succession and seedling recruitment. They are based in a range of different environments and encompass several different proposed end land uses. The paper demonstrates the utility of an hierarchical approach in assessing rehabilitation success, and that different elements within the hierarchy have differing levels of importance depending on specific minesite conditions. 22 refs., 3 figs.

  13. Case Study Observational Research: A Framework for Conducting Case Study Research Where Observation Data Are the Focus.

    Science.gov (United States)

    Morgan, Sonya J; Pullon, Susan R H; Macdonald, Lindsay M; McKinlay, Eileen M; Gray, Ben V

    2017-06-01

    Case study research is a comprehensive method that incorporates multiple sources of data to provide detailed accounts of complex research phenomena in real-life contexts. However, current models of case study research do not particularly distinguish the unique contribution observation data can make. Observation methods have the potential to reach beyond other methods that rely largely or solely on self-report. This article describes the distinctive characteristics of case study observational research, a modified form of Yin's 2014 model of case study research the authors used in a study exploring interprofessional collaboration in primary care. In this approach, observation data are positioned as the central component of the research design. Case study observational research offers a promising approach for researchers in a wide range of health care settings seeking more complete understandings of complex topics, where contextual influences are of primary concern. Future research is needed to refine and evaluate the approach.

  14. A Review of the Research in Emotionally Focused Therapy for Couples.

    Science.gov (United States)

    Wiebe, Stephanie A; Johnson, Susan M

    2016-09-01

    Emotionally Focused Therapy for Couples (EFT) is a brief evidence-based couple therapy based in attachment theory. Since the development of EFT, efficacy and effectiveness research has accumulated to address a range of couple concerns. EFT meets or exceeds the guidelines for classification as an evidence-based couple therapy outlined for couple and family research. Furthermore, EFT researchers have examined the process of change and predictors of outcome in EFT. Future research in EFT will continue to examine the process of change in EFT and test the efficacy and effectiveness of EFT in new applications and for couples of diverse backgrounds and concerns. © 2016 Family Process Institute.

  15. Prevention and Control Strategies to Counter Zika Virus, a Special Focus on Intervention Approaches against Vector Mosquitoes—Current Updates

    Directory of Open Access Journals (Sweden)

    Raj K. Singh

    2018-02-01

    Full Text Available Zika virus (ZIKV is the most recent intruder that acquired the status of global threat creating panic and frightening situation to public owing to its rapid spread, attaining higher virulence and causing complex clinical manifestations including microcephaly in newborns and Guillain Barré Syndrome. Alike other flaviviruses, the principal mode of ZIKV transmission is by mosquitoes. Advances in research have provided reliable diagnostics for detecting ZIKV infection, while several drug/therapeutic targets and vaccine candidates have been identified recently. Despite these progresses, currently there is neither any effective drug nor any vaccine available against ZIKV. Under such circumstances and to tackle the problem at large, control measures of which mosquito population control need to be strengthened following appropriate mechanical, chemical, biological and genetic control measures. Apart from this, several other known modes of ZIKV transmission which have gained importance in recent past such as intrauterine, sexual intercourse, and blood-borne spread need to be checked and kept under control by adopting appropriate precautions and utmost care during sexual intercourse, blood transfusion and organ transplantation. The virus inactivation by pasteurization, detergents, chemicals, and filtration can effectively reduce viral load in plasma-derived medicinal products. Added to this, strengthening of the surveillance and monitoring of ZIKV as well as avoiding travel to Zika infected areas would aid in keeping viral infection under check. Here, we discuss the salient advances in the prevention and control strategies to combat ZIKV with a focus on highlighting various intervention approaches against the vector mosquitoes of this viral pathogen along with presenting an overview regarding human intervention measures to counter other modes of ZIKV transmission and spread. Additionally, owing to the success of vaccines for a number of infections

  16. Research of long pulse high current diode radial insulation

    International Nuclear Information System (INIS)

    Tan Jie; Chang Anbi; Hu Kesong; Liu Qingxiang; Ma Qiaosheng; Liu Zhong

    2002-01-01

    A radial insulation structure which is used in long pulse high current diode is introduced. The theory of vacuum flashover and the idea of design are briefly introduced. In the research, cone-shaped insulator was used. The geometry structure parameters were optimized by simulating the static electrical field distribution. Experiment was done on a pulse power source with 200 ns pulse width. The maximum voltage 750 kV was obtained, and the average stand-off electrical field of insulator is about 50 kV/cm

  17. Research on High Current Pulse Discharges at IPP ASci CR

    Czech Academy of Sciences Publication Activity Database

    Koláček, Karel; Schmidt, Jiří; Prukner, Václav; Štraus, Jaroslav; Frolov, Oleksandr; Martínková, M.

    2006-01-01

    Roč. 56, suppl. B (2006), s. 259-266 ISSN 0011-4626. [Symposium on Plasma Physics and Technology/22nd./. Praha, 26.6.2006-29.6.2006] R&D Projects: GA ČR GA202/06/1324; GA MŠk 1P04LA235 Institutional research plan: CEZ:AV0Z20430508 Keywords : Pulsed high current capillary discharge * amplified spontaneous emission * soft X-ray laser Subject RIV: BL - Plasma and Gas Discharge Physics Impact factor: 0.568, year: 2006

  18. Current status of research and related activities in NAA application

    International Nuclear Information System (INIS)

    Ab Khalik bin Haji Wood

    1999-01-01

    Current activities of Analytical Chemistry Group of MINT (Malaysia Institute for Nuclear Technology Research) laboratory for elemental analysis of trace amounts in environmental samples such as air particulate matter (on air filter), soils/sediments, water, flora/fauna, oil sludge/waste sludge, and tailing/blasting slag and others, utilizing particularly NAA (Neutron Activation Analysis) method are reviewed. The laboratory participates in the IAEA-organized Interlaboratory Comparison Studies to ensure the analytical system. Other activities include analytical chemistry services with ICP-mass spectrometry and GC/GCMS to compliment the NAA and, moreover, air and marine pollution studies with participation in the UNDP/RCA/IAEA project. (S. Ohno)

  19. Research of Ve current charge interactions in the NOMAD experience

    International Nuclear Information System (INIS)

    Manola-Poggioli, E.

    1996-01-01

    Written during the two first years of the NOMAD experiment working, this thesis is divided into two parts. In the first part, a partly equipped detector gives the 1994's results. It allows to identify and to select the NOMAD main interactions (muon neutrino charging current (CC) interactions) in the target. Thank to a events selection, the origin of the produced electrons is studied to better understand simulation's programs. In the second part, neutrino-electron CC interactions represent the main background noise to the oscillations research in the electronic mode. Electrons identification's algorithms are developed and inelastic interactions kinematic properties of electron neutrinos are discussed. (TEC). 57 refs., 72 figs., 18 tabs

  20. Research highlights from the 2017 ERS International Congress: airway diseases in focus

    Directory of Open Access Journals (Sweden)

    Cecilia Andersson

    2018-03-01

    Full Text Available For another year, high-quality research studies from around the world transformed the annual ERS International Congress into a vivid platform to discuss trending research topics, to produce new research questions and to further push the boundaries of respiratory medicine and science. This article reviews only some of the high-quality research studies on asthma, chronic obstructive pulmonary disease (COPD, bronchiectasis and chronic cough that were presented during the congress through the Airway Diseases Assembly (ERS Assembly 5 and places them into the context of current knowledge and research challenges.

  1. Methodological Reflections on the Use of Asynchronous Online Focus Groups in Health Research

    Directory of Open Access Journals (Sweden)

    Sarah Williams PhD

    2012-09-01

    Full Text Available The Internet is increasingly used as a tool in qualitative research. In particular, asynchronous online focus groups are used when factors such as cost, time, or access to participants can make conducting face-to-face research difficult. In this article we consider key methodological issues involved in using asynchronous online focus groups to explore experiences of health and illness. The written nature of Internet communication, the lack of physical presence, and the asynchronous, longitudinal aspects enable participants who might not normally contribute to research studies to reflect on their personal stories before disclosing them to the researcher. Implications for study design, recruitment strategies, and ethics should be considered when deciding whether to use this method.

  2. Current utilization of research reactor on radioisotopes production in China

    Energy Technology Data Exchange (ETDEWEB)

    Liu Yishu [Nuclear Power Institute of China, Chengdu (China)

    2000-10-01

    The main technical parameters of the four research reactors and their current utilization status in radioisotope manufacture and labeling compounds preparation are described. The radioisotopes, such as Co-60 sealed source, Ir-192 sealed source, {gamma}-knife source, I-131, I-125, Sm-153, P-32 series products, In-113m generator, Tc-99m gel generator, Re-188 gel generator, C-14, Ba-131, Sr-89, {sup 90}Y, etc., and their labeling compounds prepared from the reactor produced radionuclides, such as I-131-MIBG, I-131-Hippure, I-131-capsul, Sm-153-EDTMP, Re-186-HEDP, Re-186-HA, C-14-urea, and radioimmunoassay kits etc. are presented as well. Future development plan of radioisotopes and labeling compounds in China is also given. Simultaneously, the possibility and methods of bilateral or multilateral co-operation in utilization of research reactor, personnel and technology exchange of radioisotope production and labeling compounds is also discussed. (author)

  3. Current utilization of research reactor on radioisotopes production in China

    International Nuclear Information System (INIS)

    Liu Yishu

    2000-01-01

    The main technical parameters of the four research reactors and their current utilization status in radioisotope manufacture and labeling compounds preparation are described. The radioisotopes, such as Co-60 sealed source, Ir-192 sealed source, γ-knife source, I-131, I-125, Sm-153, P-32 series products, In-113m generator, Tc-99m gel generator, Re-188 gel generator, C-14, Ba-131, Sr-89, 90 Y, etc., and their labeling compounds prepared from the reactor produced radionuclides, such as I-131-MIBG, I-131-Hippure, I-131-capsul, Sm-153-EDTMP, Re-186-HEDP, Re-186-HA, C-14-urea, and radioimmunoassay kits etc. are presented as well. Future development plan of radioisotopes and labeling compounds in China is also given. Simultaneously, the possibility and methods of bilateral or multilateral co-operation in utilization of research reactor, personnel and technology exchange of radioisotope production and labeling compounds is also discussed. (author)

  4. Food reward system: current perspectives and future research needs.

    Science.gov (United States)

    Alonso-Alonso, Miguel; Woods, Stephen C; Pelchat, Marcia; Grigson, Patricia Sue; Stice, Eric; Farooqi, Sadaf; Khoo, Chor San; Mattes, Richard D; Beauchamp, Gary K

    2015-05-01

    This article reviews current research and cross-disciplinary perspectives on the neuroscience of food reward in animals and humans, examines the scientific hypothesis of food addiction, discusses methodological and terminology challenges, and identifies knowledge gaps and future research needs. Topics addressed herein include the role of reward and hedonic aspects in the regulation of food intake, neuroanatomy and neurobiology of the reward system in animals and humans, responsivity of the brain reward system to palatable foods and drugs, translation of craving versus addiction, and cognitive control of food reward. The content is based on a workshop held in 2013 by the North American Branch of the International Life Sciences Institute. © The Author(s) 2015. Published by Oxford University Press on behalf of the International Life Sciences Institute.

  5. The International Permafrost Association: current initiatives for cryospheric research

    Science.gov (United States)

    Schollaen, Karina; Lewkowicz, Antoni G.; Christiansen, Hanne H.; Romanovsky, Vladimir E.; Lantuit, Hugues; Schrott, Lothar; Sergeev, Dimitry; Wei, Ma

    2015-04-01

    The International Permafrost Association (IPA), founded in 1983, has as its objectives to foster the dissemination of knowledge concerning permafrost and to promote cooperation among persons and national or international organizations engaged in scientific investigation and engineering work on permafrost. The IPA's primary responsibilities are convening International Permafrost Conferences, undertaking special projects such as preparing databases, maps, bibliographies, and glossaries, and coordinating international field programs and networks. Membership is through adhering national or multinational organizations or as individuals in countries where no Adhering Body exists. The IPA is governed by its Executive Committee and a Council consisting of representatives from 26 Adhering Bodies having interests in some aspect of theoretical, basic and applied frozen ground research, including permafrost, seasonal frost, artificial freezing and periglacial phenomena. This presentation details the IPA core products, achievements and activities as well as current projects in cryospheric research. One of the most important core products is the circumpolar permafrost map. The IPA also fosters and supports the activities of the Global Terrestrial Network on Permafrost (GTN-P) sponsored by the Global Terrestrial Observing System, GTOS, and the Global Climate Observing System, GCOS, whose long-term goal is to obtain a comprehensive view of the spatial structure, trends, and variability of changes in the active layer thickness and permafrost temperature. A further important initiative of the IPA are the biannually competitively-funded Action Groups which work towards the production of well-defined products over a period of two years. Current IPA Action Groups are working on highly topical and interdisciplinary issues, such as the development of a regional Palaeo-map of Permafrost in Eurasia, the integration of multidisciplinary knowledge about the use of thermokarst and permafrost

  6. Current safety issues related to research reactor operation

    International Nuclear Information System (INIS)

    Alcala-Ruiz, F.

    2000-01-01

    The Agency has included activities on research reactor safety in its Programme and Budget (P and B) since its inception in 1957. Since then, these activities have traditionally been oriented to fulfil the Agency's functions and obligations. At the end of the decade of the eighties, the Agency's Research Reactor Safety Programme (RRSP) consisted of a limited number of tasks related to the preparation of safety related publications and the conduct of safety missions to research reactor facilities. It was at the beginning of the nineties when the RRSP was upgraded and expanded as a subprogramme of the Agency's P and B. This subprogramme continued including activities related to the above subjects and started addressing an increasing number of issues related to the current situation of research reactors (in operation and shut down) around the world such as reactor ageing, modifications and decommissioning. The present paper discusses some of the above issues as recognised by various external review or advisory groups (e.g., Peer Review Groups under the Agency's Performance Programme Appraisal System (PPAS) or the standing International Nuclear Safety Advisory Group (INSAG)) and the impact of their recommendations on the preparation and implementation of the part of the Agency's P and B relating to the above subject. (author)

  7. Viewpoint on the current status of researches on sepsis

    Directory of Open Access Journals (Sweden)

    Zheng-guo WANG

    2012-11-01

    Full Text Available Sepsis is a common complication after severe trauma and burn, and also one of the main causes of death. Recently, although some new progresses were seen in antibiotic therapy, the mortality of sepsis is still on the rise, and the death rate as a result of sepsis is higher than a total of that of prostate cancer, breast cancer and AIDS. Therefore, sepsis has obviously become one of the serious ailments threatening human health. The present paper introduced the international definition of sepsis, severe sepsis and septic shock, the current researches on diagnosis and therapy, and proposed that we should not only pay attention to pathogenesis and treatment, but also to sepsis prevention in sepsis researches, and we should try to find out the breakthrough in the interaction and dynamic balance between human being and pathogenic factors. Researches on the strategies to revert strong toxicity of infectious agents to non-toxic or weak pathogenic factors, and to conduct further research concerning biological characteristics of microorganisms and mechanism of drug resistance in order to render them to lose the drug resistance ability, or to increase its sensitivity to the drugs. The above suggested approaches might form the future strategies for preventing and controlling sepsis.

  8. Ten Reasons to Still Keep the Focus on Teen Childbearing. Research Brief, Publication #2009-10

    Science.gov (United States)

    Holcombe, Emily; Peterson, Kristen; Manlove, Jennifer; Scarupa, Harriet J., Ed.

    2009-01-01

    In 2002, Child Trends drew on statistics and research findings to produce a report called "Ten Reasons to Keep the Focus on Teen Childbearing." That report took note of the steady decline in the nation's teenage pregnancy and childbearing rates, beginning in 1991, while citing multiple reasons to continue to be concerned about teen childbearing.…

  9. Broadening the focus of bat conservation and research in the USA for the 21st century

    Science.gov (United States)

    Theodore Weller; Paul Cryan; O’Shea Thomas

    2009-01-01

    Appropriately, bat conservation in the USA during the 20th century focused on species that tend to aggregate in large numbers and locations (e.g. maternity roosts, hibernacula) where populations are most vulnerable. Extensive research into habitat needs (primarily for roosting) of reproductive females during the previous 2 decades has produced a wealth of information...

  10. Focus on CSIR research in pollution and waste: Integrated waste management

    CSIR Research Space (South Africa)

    Godfrey, Linda K

    2007-08-01

    Full Text Available Research into integrated waste management is undertaken in view of the impact of increasing populations and a strong national focus on industrial, agricultural and urban growth that is likely to result in the increase of human induced pressures...

  11. Teachers' Commitment To, and Experiences of, the Teaching Profession in Tanzania: Findings of Focus Group Research

    Science.gov (United States)

    Mkumbo, Kitila A. K.

    2012-01-01

    This qualitative study examined teachers' commitment to, and experiences of, the teaching profession in six regions of Tanzania. The study used focus group discussions as research method and data collection tool. Twenty four groups were conducted, with group membership ranging from five to nine participants. The results show that the teachers'…

  12. ["Good dying"--definition and current state of research].

    Science.gov (United States)

    Hutter, Nico; Stößel, Ulrich; Meffert, Cornelia; Körner, Mirjam; Bozzaro, Claudia; Becker, Gerhild; Baumeister, Harald

    2015-08-01

    The advances of modern medicine did not only result in prolongation of life expectancy, but also led to a shift from dying at home to dying in public institutions. In western countries most people die at advanced age in medical facilities. Hence, the question regarding the conditions, which should be provided by society and especially medicine, to allow terminally ill people to experience "good dying" is substantial. For this purpose, an examination of patients', family members' and health care providers' understanding of the term " good dying" is required. The present paper aims at shedding light on the term "good dying" and to summarize the current state of research. Therefore, the attributes of "good dying" will be described from the perspectives of patients, family members and health care providers, which are discussed and examined in current medical-sociological research. These attributes can be illustrated on three dimensions: Quality of life at the end of life (e. g. pain relief, mental well-being), quality of dying (e. g. avoiding prolonged dying, autonomy, presence of relatives) and quality of health care at the end of life (e. g. patient-oriented health care, positive communication between health care providers and patients, availability of guidelines). Although the attributes of "good dying" are described in detail in the existing literature, further studies have to clarify the relevance and impact of these attributes as predictors of "good dying". © Georg Thieme Verlag KG Stuttgart · New York.

  13. [Research progress on current pharmacokinetic evaluation of Chinese herbal medicines].

    Science.gov (United States)

    Li, Guofu; Zhao, Haoru; Yang, Jin

    2011-03-01

    In order to prove safety and efficacy, herbal medicines must undergo the rigorous scientific researches such as pharmacokinetic and bioavailability, before they are put on the market in the foreign countries. Botanical Drug Products promulgated by the US FDA could guide industry sponsors to develop herbal drugs, which was also an important reference for investigating Chinese herbal medicines. This paper reviews and discusses novel approaches for how to assess systemic exposure and pharmacokinetic of Chinese herbal medicines, which were in line with FDA guidance. This mainly focus on identifying pharmacokinetic markers of botanical products, integral pharmacokinetic study of multiple components, Biopharmaceutics drug disposition classification system, and population pharmacokinetic-pharmacodynamic study in herb-drug interaction.

  14. On the Development of Intelligent Railway Information and Safety Systems: An Overview of Current Research

    Directory of Open Access Journals (Sweden)

    Dániel Tokody

    2018-03-01

    Full Text Available The present article focuses on the research and development planning for innovative railway systems. Within such a general framework, the specific objectives of the research have been defined within the framework of a large Intelligent Railway System project in Hungary. Our theoretical research work at the university is combined with practical experience gained at the Hungarian State Railways. In the course of this research work, the development of an intelligent railway system has been investigated by leveraging on the fruitful cooperation between academic and industrial partners, in order to promote the application and integration possibilities of the development results, as well as the introduction of innovative components in the railway system. In such a context, this article discusses the research plan, preliminary and long-term expected results, sharing objectives and experiences with the aim of providing novel views in an extremely current and challenging field of research.

  15. Precision viticulture in Brazil: Current research status on wine grape

    Directory of Open Access Journals (Sweden)

    Miele Alberto

    2014-01-01

    Full Text Available Technologies associated to precision viticulture (PV are not currently used by Brazilian growers. To overcome this situation, a research is being carried out since 2011 in a vineyard of Merlot using a wide range of PV technologies. During this period, several PV research activities were performed which will be concluded in a couple of years. Therefore, final results depend on further variable evaluation which should be done by means of geostatistic, Geographic Information Systems and Principal Component Analysis. This paper briefly presents a series of methodological procedures used in different ways to attain the objective of this research project. In the sequence, it describes one final result and nine partial ones. Morphological and physicochemical analyses of soil showed that the vineyards are established on three taxonomic classes of soil – Argissolo, Cambissolo and Neossolo −, which are formed by ten mapping units. The partial results are mainly related to the utilization of GIS, modeling and must and wine composition of five mapping units; however they show results of only one year. With the complete set of analyses, data should be spatialized and maps prepared. Then, it will be possible to recommend different practices to each soil type and to aid oenologists to direct wines to a specific quality pattern.

  16. Current research progresses on calf rearing and nutrition in China

    Institute of Scientific and Technical Information of China (English)

    DIAO Qi-yu; ZhAng Rong; Tu Yan

    2017-01-01

    Calves are the reserve forces for dairy cattle. Scientific rearing strategy of calves is the basis of efficient cattle breeding. However, many problems exist in current rearing systems of calves and restrict the sustainable development of dairy cattle in China. The absence of basic research is the most highlighted problem among them. Recent researches on growth performance, nutrient digestibility, blood biochemical indices and rumen development in calves were summarized in this paper. Additionally, the optimal levels of energy and protein in milk replacer and starter diets for calves were indicated, and limiting amino acids for calves fed different diets were discussed. A variety of additives, such as acidifiers, probiotics and polysaccharides, are regarded as promising alternatives to antibiotics to reduce disease in calves. Dietary supplementations of these additives have positive effects on growth and health of calves. However, studies on the nutrition of vitamins and minerals in calves have been seldom done, and deserve our further researches. To sum up, the postnatal period is one of the most critical "windows" for rumen manipulation and epigenetic regulation. Any changes from environments, especially early nutrition, may produce long-term effects on growth, health and milk yields in adult cattle.

  17. Current research trends in mountain biodiversity in NW Europe

    Directory of Open Access Journals (Sweden)

    Väisänen, Risto A.

    1998-12-01

    Full Text Available Focusing on four themes in relation to biodiversity (vegetation science, keystone grazers, long-term studies and protected areas, a synthesis of current research in the mountain areas of Fennoscandia, Iceland and Scotland is presented. Recent relevant advances in vegetation science include classifications of mountain habitats which together with species distribution maps offer new possibilities for analysis. Generalisations emerging from comparisons of the ecology and ecophysiology of plants between different mountain areas are greatly needed. Further studies on the ecological impacts of keystone grazers are urgently required because of the alarming rate of degradation of mountain habitats. The topics highlighted from northern Fennoscandia include (i the effect of overgrazing by reindeer on the cover of foliose lichens and on the regeneration of mountain birch, (ii the ecological interactions between the autumnal moth and mountain birch, and (Hi the effect of rodents on vegetation. Long-term studies of slow processes to capture rare but important events are needed to better understand the functioning of mountain ecosystems. Examples of such studies are presented for (i the moss Racomitrium lanuginosum as an indicator of airborne nitrogen pollution, (ii research based on cyclic oscillations of vole numbers, and (Hi the application of breeding birds in environmental assessment. The conservation of appropriate areas is important for mountain biodiversity. Mountain habitats have been protected extensively in northern Europe. The evaluation of how representative the existing areas are and how to use them for research need international co-ordination.

    [fr] On présente une synthèse de la recherche actuelle dans les régions de montagne de la Scandinavie, l'Islande et l'Ecosse, centrée sur quatre sujets autour de la biodiversité (science de la végétation, herbivores principaux, études à long terme et zones protégées. Les r

  18. Government policy, research and stakeholder confidence - Current Trends in Canada

    International Nuclear Information System (INIS)

    Letourneau, Carmel

    2006-01-01

    uncertainties; - Assure adequate human capacity to manage the program throughout its existence to maintain competence and credibility; - Enhance scientific understanding to improve confidence in predictions and to evaluate potential program improvements; - Confirm performance or identify anomalies during and after program operations and thereby increase confidence; - Clearly demonstrate to citizens an ongoing capability to manage the enterprise and to respond to their concerns and desires; - Be able to enact mid-course corrections in response to new information or societal decisions by adapting to new designs, new regional, national or international institutional changes, or new international standards; - Be able to adapt to new capabilities developed externally to the program that show promise of improving program success. Ms. Letourneau addressed the role of the public and private sector in conducting research on RWM in Canada. The Government of Canada has clearly indicated that the responsibility for providing sound scientific data for proposed practices rests with the proponent who is taking action associated with the risk of potential serious harm. Where it is less clear that the proponent should shoulder the entire responsibility for research programs, the Government step in and assist the proponent or the general industry in question. The relationship between research and Government policy focuses on the public good and always aspires to public confidence. It cannot focus only on ideas and technologies with commercial potential. Its top priority must retain the public interest of present and future generations of Canadians. The Government is interested in supporting research which responds to public priorities of the day. The presentation reviewed the functional objectives of government research, and noted that increasingly, the setting of research priorities now involves more intensive and extensive public consultations. It was noted that allocation of responsibility

  19. Sediment pollution of the Elbe River side structures - current research

    Science.gov (United States)

    Chalupova, Dagmar; Janský, Bohumír

    2016-04-01

    The contribution brings the summarized results of a long-term research on sediment pollution of side structures of the Elbe River over the last 14 years. The investigation has been focused on old anthropogenic pollution of sediment cores taken from fluvial lakes and floodplain, as the sampling of deeper sediments outside the riverbed is not a part of systematic monitoring of sediment pollution of the Elbe. The Elbe River floodplain has been influenced by human activities since the Middle Ages, but the main anthropogenic pollution have been produced in the 20th century. The studied localities were chosen with the respect to the distance from the source of industrial pollution, the intensity of hydrological communication with the river and the surrounding landuse to determine the extend and the level of anthropogenic contamination in the Elbe River floodplain ecosystem. Apart from bathymetric measurements, observation of the hydrological regime in several fluvial lakes or water quality sampling at some localities, the research was focused above all on determination of metal concentrations (Ag, Cd, Cr, Cu, Fe, Hg, Mn, Pb, Zn) in all taken sediment cores, specific organic compounds (PCBs, DDT, HCH, HCB, PAHs etc.), total organic carbon at some localities and grain structure analyses. The data were also compared with the results of systematic sediment monitoring from the nearest riverbed sampling stations on the Elbe River. The highest concentrations of metals and specific organic compounds were determined in the sediments taken from fluvial lakes and floodplain (Zimní přístav PARAMO, Rosice fuvial Lake, Libiš pool etc.) situated in the vicinity of the main Elbe River polluters - Synthesia chemical plant and PARAMO refinery in Pardubice or Spolana chemical plant near Neratovice. However, there was also determined a significant role of the hydrological communication with the river proved with lower sediment pollution in separated localities. The realization of the

  20. Qualitative ergonomics/human factors research in health care: Current state and future directions.

    Science.gov (United States)

    Valdez, Rupa Sheth; McGuire, Kerry Margaret; Rivera, A Joy

    2017-07-01

    The objective of this systematic review was to understand the current state of Ergonomics/Human Factors (E/HF) qualitative research in health care and to draw implications for future efforts. This systematic review identified 98 qualitative research papers published between January 2005 and August 2015 in the seven journals endorsed by the International Ergonomics Association with an impact factor over 1.0. The majority of the studies were conducted in hospitals and outpatient clinics, were focused on the work of formal health care professionals, and were classified as cognitive or organizational ergonomics. Interviews, focus groups, and observations were the most prevalent forms of data collection. Triangulation and data archiving were the dominant approaches to ensuring rigor. Few studies employed a formal approach to qualitative inquiry. Significant opportunities remain to enhance the use of qualitative research to advance systems thinking within health care. Copyright © 2017 Elsevier Ltd. All rights reserved.

  1. Research on pinches driven by Speed-2 generator: Hard X-ray and neutron emission in plasma focus configuration

    Energy Technology Data Exchange (ETDEWEB)

    Soto, L.; Moreno, J.; Silva, P.; Sylvester, G.; Zambra, M.; Pavez, C. [Comision Chilena de Energia Nuclear, Santiago (Chile); Pavez, C. [Universidad de Concepcion (Chile); Raspa, V. [Buenos Aires Univ., PLADEMA, CONICET and INFIP (Argentina); Castillo, F. [Insitituto de Ciencias Nucleares, UNAM (Mexico); Kies, W. [Heinrich-Heine-Univ., Dusseldorf (Germany)

    2004-07-01

    Speed-2 is a generator based on Marx technology and was designed in the University of Dusseldorf. Speed-2 consists on 40 +/- Marx modules connected in parallel (4.1 {mu}F equivalent Marx generator capacity, 300 kV, 4 MA in short circuit, 187 kJ, 400 ns rise time, dI/dt {approx} 10{sup 13} A/s). Currently Speed-2 is operating at CCHEN (Chilean nuclear energy commission), being the most powerful and energetic device for dense transient plasma in the Southern Hemisphere. Most of the previous works developed in Speed-2 at Dusseldorf were done in a plasma focus configuration for soft X-ray emission and the neutron emission from Speed-2 was not completely studied. The research program at CCHEN considers experiments in different pinch configurations (plasma focus, gas puffed plasma focus, gas embedded Z-pinch, wire arrays) at current of hundred of kilo- to mega-amperes, using the Speed-2 generator. The Chilean operation has begun implementing and developing diagnostics in a conventional plasma focus configuration operating in deuterium in order to characterize the neutron emission and the hard X-ray production. Silver activation counters, plastics CR39 and scintillator-photomultiplier detectors are used to characterize the neutron emission. Images of metallic plates with different thickness are obtained on commercial radiographic film, Agfa Curix ST-G2, in order to characterize an effective energy of the hard X-ray outside of the discharge. (authors)

  2. Munchausen by internet: current research and future directions.

    Science.gov (United States)

    Pulman, Andy; Taylor, Jacqui

    2012-08-22

    The Internet has revolutionized the health world, enabling self-diagnosis and online support to take place irrespective of time or location. Alongside the positive aspects for an individual's health from making use of the Internet, debate has intensified on how the increasing use of Web technology might have a negative impact on patients, caregivers, and practitioners. One such negative health-related behavior is Munchausen by Internet. Munchausen by Internet occurs when medically well individuals fake recognized illnesses in virtual environments, such as online support groups. This paper focuses on the aspect of Munchausen by Internet in which individuals actively seek to disrupt groups for their own satisfaction, which has not yet been associated with the wider phenomena of Internet trolls (users who post with the intention of annoying someone or disrupting an online environment). A wide-ranging review was conducted to investigate the causes and impacts of online identity deception and Munchausen by Internet drawing on academic research and case studies reported online and in the media. The limited research relating to motivation, opportunity, detection, effects, and consequences of Munchausen by Internet is highlighted and it is formally linked to aspects of trolling. Case studies are used to illustrate the phenomenon. What is particularly worrying is the ease with which the deception can be carried out online, the difficulty in detection, and the damaging impact and potential danger to isolated victims. We suggest ways to deal with Munchausen by Internet and provide advice for health group facilitators. We also propose that Munchausen by Internet and Munchausen by Internet trolling should be formally acknowledged in a revised version of the Diagnostic and Statistical Manual DSM-5. This will assist in effectively identifying and minimizing the growth of this behavior as more people seek reassurance and support about their health in the online environment. We

  3. Current and future geothermal research in New Zealand

    International Nuclear Information System (INIS)

    Graham, I.J.; Browne, P.; Christenson, B.W.; Hunt, T.M.; Weir, G.

    2000-01-01

    Research programs by Crown Research Institutes (Geological and Nuclear Sciences Ltd. and Industrial Research Ltd.), university departments (Auckland, Massey and Victoria), power companies and private consultancies aim to obtain a better understanding of currently producing geothermal fields in New Zealand, and of deep geothermal systems which might have potential for future resource development. Research is also being directed at industrial and environmental issues related to exploitation, water-rock alteration processes, changes in shallow geothermal systems with time, and mineralisation as it relates to epithermal ore formation. The chemical and physical environment of geothermal reservoirs in the Taupo Volcanic Zone (e.g. Thames, Kawerau, Ohaaki, Ngatamariki, Wairakei, Tongariro, Tauhara and Tokaanu-Waihi) is being quantified with the aim of developing a suite of magma to ambient production scenarios using numerical, reactive transport models. A variety of geological, geochemical and geophysical techniques including fluid inclusion geothermometry, stable isotope analysis, electromagnetic, micro-seismic and magnetotelluric analysis is providing high quality input data. Through experimentation and computer modelling, criteria for assessing the optimal depths for re-injection of production effluents are being developed, and related problems such as silica and calcite scaling, pipeline insulation and chemical corrosion investigated. Paths, flow mechanisms and flow rates of re-injection plumes are being modelled using electrical resistivity, micro-gravity and radioisotope tracer methods. Environmental effects related to testing and development, presently causing concern amongst local authorities and the public, are being quantitatively assessed, and recommendations made to mitigate them. The mechanical and petrological properties of rocks in shallow aquifers undergoing ground subsidence are being determined, and the extent and style of ground deformation investigated

  4. Patient informed governance of distributed research networks: results and discussion from six patient focus groups.

    Science.gov (United States)

    Mamo, Laura A; Browe, Dennis K; Logan, Holly C; Kim, Katherine K

    2013-01-01

    Understanding how to govern emerging distributed research networks is essential to their success. Distributed research networks aggregate patient medical data from many institutions leaving data within the local provider security system. While much is known about patients' views on secondary medical research, little is known about their views on governance of research networks. We conducted six focus groups with patients from three medical centers across the U.S. to understand their perspectives on privacy, consent, and ethical concerns of sharing their data as part of research networks. Participants positively endorsed sharing their health data with these networks believing that doing so could advance healthcare knowledge. However, patients expressed several concerns regarding security and broader ethical issues such as commercialism, public benefit, and social responsibility. We suggest that network governance guidelines move beyond strict technical requirements and address wider socio-ethical concerns by fully including patients in governance processes.

  5. Consortium for Offshore Aviation Research : description of current projects

    International Nuclear Information System (INIS)

    Anon.

    1998-01-01

    The five projects which are currently underway or being evaluated through the Consortium for Offshore Aviation Research (COAR) were described. The projects are: (1) the use of narrow-beam, high intensity searchlights as approach aids for helicopter landings on helidecks in low visibility conditions, (2) establishment of a precipitation and fog characterization facility forecasting, (3) use of ice-phobic materials for airframe anti-icing, (4) use of differential global positioning satellite systems for offshore operations, and (5) the development of a virtual reality head-up-display for the approach to the Hibernia helideck (or any other helideck) to facilitate low visibility landings. Seed funding for these projects has been provided by the European Space Agency. Additional support is being provided by Hibernia, Petro-Canada, Husky Oil and Chevron Oil Canada. Initiatives to increase the number of partners are underway. 1 fig

  6. Current NDT activities at Cekmece Nuclear Research and Training Center

    International Nuclear Information System (INIS)

    Ekinci, S.

    2004-01-01

    Nondestructive testing (NDT) activities at Cekmece Nuclear Research and Training Center (CNAEM) has been initiated in the Industrial Application Department of the Center which was established in 1976 as the Radioisotope Applications Group for Industry. The Department started its first NDT activity with industrial radiography. The NDT activities have been developed by the support of various national (State Planning Organization (DPT)) and international (IAEA and UNDP) projects. Today, there are five basic NDT techniques (radiography, ultrasonic, magnetic particle, liquid penetrant and eddy current) used in the Industrial Application Department. The Department arranges routinely NDT qualification courses according to ISO 9712 and TS EN 473 standards for level 1 and 2 for Turkish Industry. It also carries out national DPT and IAEA Technical Co-operation projects and gives NDT services in the laboratory and in the field. Digital radiography and digital ultrasonic techniques are being used in advanced NDT applications. This paper describes the NDT activities of CNAEM. (author)

  7. Current status of ethnobotany research on palms from Peru

    Directory of Open Access Journals (Sweden)

    Joaquina Albán

    2014-03-01

    Full Text Available The current situation concerning research in ethnobotany and economic botany of Peruvian palms is analyzed through a review of the literature with emphasis on knowledge related to uses and vernacular names. Of the 136 Peruvian palm species, 104 have at least one use. A total of 268 different uses distributed in 16 categories were registered. The most frequent categories are "construction", "edible", "craft industry" and "medicinal". There are 109 palm species with at least one vernacular name in Peru. The consulted literature is analyzed in four categories: (i general studies in economic botany, (ii ethnographic and ethnobiological studies, (iii studies of South-American palms of economic interest, (iv studies that exclusively deal with the useful Peruvian palms. Ethnobotanical knowledge of Peruvian palms proves to be essentially descriptive, with much repetitive information. Studies that significantly contribute to the genetic or agronomical improvement of the economically promising palms are rare.

  8. Current Research Status of KHNP for Site Risk

    Energy Technology Data Exchange (ETDEWEB)

    Oh, Kyemin; Jeon, Ho-Jun; Bahng, Ki-In; Na, Jang-Hwan [KHNP CRI, Daejeon (Korea, Republic of)

    2016-10-15

    In Korea, by the geographical characteristics, many Nuclear Power Plants (NPPs) have been constructed and operated at a single site. This is above average level or number of plants per site in the world. For this reason, the public concerns for the safety of nuclear facilities increased after Fukushima Daiichi accident. As a result, comprehensive risk assessment and management for the site which have multi-unit NPPs were strongly asked. Currently, to solve it, many researches and projects has carried out by various Korean companies, research centers, and regulatory authorities. In this paper, R and D plans of KHNP for multi-unit risk were summarized. Firstly, the needs of multi-unit PSA were reviewed. R and D activities and plans of KHNP were summarized in the last part. In this paper, we summarized the R and D plans of KHNP for assessing the multi-unit risk. Currently, multi-unit risk or multi-unit PSA are important and practical issues in both nuclear industry and national energy policy. After Fukushima accident, several countries stopped the construction and the operation of NPPs, other countries which is maintaining the NPPs are being strongly asked to assess the risk for multi-unit NPPs at the same site. Because of Korean geographical characteristics, the number of NPPs which are above average level or number of plants per site in the world is being constructed and operated at a single site. The population density nearby each site is considered to be higher than that of other countries.

  9. Current Research Status of KHNP for Site Risk

    International Nuclear Information System (INIS)

    Oh, Kyemin; Jeon, Ho-Jun; Bahng, Ki-In; Na, Jang-Hwan

    2016-01-01

    In Korea, by the geographical characteristics, many Nuclear Power Plants (NPPs) have been constructed and operated at a single site. This is above average level or number of plants per site in the world. For this reason, the public concerns for the safety of nuclear facilities increased after Fukushima Daiichi accident. As a result, comprehensive risk assessment and management for the site which have multi-unit NPPs were strongly asked. Currently, to solve it, many researches and projects has carried out by various Korean companies, research centers, and regulatory authorities. In this paper, R and D plans of KHNP for multi-unit risk were summarized. Firstly, the needs of multi-unit PSA were reviewed. R and D activities and plans of KHNP were summarized in the last part. In this paper, we summarized the R and D plans of KHNP for assessing the multi-unit risk. Currently, multi-unit risk or multi-unit PSA are important and practical issues in both nuclear industry and national energy policy. After Fukushima accident, several countries stopped the construction and the operation of NPPs, other countries which is maintaining the NPPs are being strongly asked to assess the risk for multi-unit NPPs at the same site. Because of Korean geographical characteristics, the number of NPPs which are above average level or number of plants per site in the world is being constructed and operated at a single site. The population density nearby each site is considered to be higher than that of other countries

  10. Experimental Study of Current Discharge Behavior and Hard X-ray Anisotropy by APF Plasma Focus Device

    Science.gov (United States)

    Habibi, M.; Amrollahi, R.; Attaran, M.

    2009-03-01

    Amirkabir (APF) is a new Mather-type plasma focus device (16 kV, 36 μf, and 115 nH). In this work we present some experimental results as variation of discharge current signal respect to applied voltage at the optimum pressure, focusing time of plasma versus gas pressure, and variations of current discharge with different insulator sleeve dimensions. As we prospected optimum pressure tending to increase as we tried to higher voltage levels. The time taken by the current sheath to lift-off the insulator surface and therefore quality of pinched plasma depends on the length of the insulator sleeve. The results show that the insulator diameter can influence on pinch quality. Behavior of hard X-ray (HXR) signals with the pressure and also anisotropy of HXR investigated by the use of two scintillation detectors. The distribution of HXR intensity shows a large anisotropy with a maximum intensity between 22.5° and 45° and also between -22.5° and -67.5°.

  11. High current density ion beam obtained by a transition to a highly focused state in extremely low-energy region

    Energy Technology Data Exchange (ETDEWEB)

    Hirano, Y., E-mail: y.hirano@aist.go.jp, E-mail: hirano.yoichi@phys.cst.nihon-u.ac.jp [Innovative Plasma Processing Group, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki 305-8568 (Japan); College of Science and Technologies, Nihon University, Chiyodaku, Tokyo 101-0897 (Japan); Kiyama, S.; Koguchi, H. [Innovative Plasma Processing Group, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki 305-8568 (Japan); Fujiwara, Y.; Sakakita, H. [Innovative Plasma Processing Group, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki 305-8568 (Japan); Department of Engineering Mechanics and Energy, University of Tsukuba, Ibaraki 305-8577 (Japan)

    2015-11-15

    A high current density (≈3 mA/cm{sup 2}) hydrogen ion beam source operating in an extremely low-energy region (E{sub ib} ≈ 150–200 eV) has been realized by using a transition to a highly focused state, where the beam is extracted from the ion source chamber through three concave electrodes with nominal focal lengths of ≈350 mm. The transition occurs when the beam energy exceeds a threshold value between 145 and 170 eV. Low-level hysteresis is observed in the transition when E{sub ib} is being reduced. The radial profiles of the ion beam current density and the low temperature ion current density can be obtained separately using a Faraday cup with a grid in front. The measured profiles confirm that more than a half of the extracted beam ions reaches the target plate with a good focusing profile with a full width at half maximum of ≈3 cm. Estimation of the particle balances in beam ions, the slow ions, and the electrons indicates the possibility that the secondary electron emission from the target plate and electron impact ionization of hydrogen may play roles as particle sources in this extremely low-energy beam after the compensation of beam ion space charge.

  12. Postinfectious Functional Gastrointestinal Disorders: A Focus on Epidemiology and Research Agendas

    OpenAIRE

    Deising, Adam; Gutierrez, Ramiro L.; Porter, Chad K.; Riddle, Mark S.

    2013-01-01

    Epidemiologic research is fundamental and complementary to our understanding of disease and development of primary, secondary, and tertiary interventions. To put the current evidence into context and identify gaps and research priorities in the areas of disease attribution, burden of disease, clinical characterization, and management of postinfectious functional gastrointestinal disorders (PI-FGDs), we took a multidisciplinary approach from the domains of infectious disease, gastroenterology,...

  13. Global fate of POPs: Current and future research directions

    International Nuclear Information System (INIS)

    Lohmann, Rainer; Breivik, Knut; Dachs, Jordi; Muir, Derek

    2007-01-01

    For legacy and emerging persistent organic pollutants (POPs), surprisingly little is still known in quantitative terms about their global sources and emissions. Atmospheric transport has been identified as the key global dispersal mechanism for most legacy POPs. In contrast, transport by ocean currents may prove to be the main transport route for many polar, emerging POPs. This is linked to the POPs' intrinsic physico-chemical properties, as exemplified by the different fate of hexachlorocyclohexanes in the Arctic. Similarly, our current understanding of POPs' global transport and fate remains sketchy. The importance of organic carbon and global temperature differences have been accepted as key drivers of POPs' global distribution. However, future research will need to understand the various biogeochemical and geophysical cycles under anthropogenic pressures to be able to understand and predict the global fate of POPs accurately. - Future studies into the global fate of POPs will need to pay more attention to the various biogeochemical and anthropogenic cycles to better understand emissions, transport and sinks

  14. Global fate of POPs: Current and future research directions

    Energy Technology Data Exchange (ETDEWEB)

    Lohmann, Rainer [Graduate School of Oceanography, University of Rhode Island, Narragansett, RI 02882-1197 (United States)], E-mail: lohmann@gso.uri.edu; Breivik, Knut [Norwegian Institute for Air Research, PO Box 100, NO-2027 Kjeller (Norway); University of Oslo, Department of Chemistry, PO Box 1033, NO-0315 Oslo (Norway); Dachs, Jordi [Department of Environmental Chemistry, Institute of Chemical and Environmental Research (IIQAB-CSIC), Jordi Girona 18-26, Barcelona 08034 (Spain); Muir, Derek [Aquatic Ecosystem Protection Research Division, Environment Canada, 867 Lakeshore Road, Burlington, ON L7R4A6 (Canada)

    2007-11-15

    For legacy and emerging persistent organic pollutants (POPs), surprisingly little is still known in quantitative terms about their global sources and emissions. Atmospheric transport has been identified as the key global dispersal mechanism for most legacy POPs. In contrast, transport by ocean currents may prove to be the main transport route for many polar, emerging POPs. This is linked to the POPs' intrinsic physico-chemical properties, as exemplified by the different fate of hexachlorocyclohexanes in the Arctic. Similarly, our current understanding of POPs' global transport and fate remains sketchy. The importance of organic carbon and global temperature differences have been accepted as key drivers of POPs' global distribution. However, future research will need to understand the various biogeochemical and geophysical cycles under anthropogenic pressures to be able to understand and predict the global fate of POPs accurately. - Future studies into the global fate of POPs will need to pay more attention to the various biogeochemical and anthropogenic cycles to better understand emissions, transport and sinks.

  15. Psychological Therapies for Auditory Hallucinations (Voices): Current Status and Key Directions for Future Research

    Science.gov (United States)

    Thomas, Neil; Hayward, Mark; Peters, Emmanuelle; van der Gaag, Mark; Bentall, Richard P.; Jenner, Jack; Strauss, Clara; Sommer, Iris E.; Johns, Louise C.; Varese, Filippo; García-Montes, José Manuel; Waters, Flavie; Dodgson, Guy; McCarthy-Jones, Simon

    2014-01-01

    This report from the International Consortium on Hallucinations Research considers the current status and future directions in research on psychological therapies targeting auditory hallucinations (hearing voices). Therapy approaches have evolved from behavioral and coping-focused interventions, through formulation-driven interventions using methods from cognitive therapy, to a number of contemporary developments. Recent developments include the application of acceptance- and mindfulness-based approaches, and consolidation of methods for working with connections between voices and views of self, others, relationships and personal history. In this article, we discuss the development of therapies for voices and review the empirical findings. This review shows that psychological therapies are broadly effective for people with positive symptoms, but that more research is required to understand the specific application of therapies to voices. Six key research directions are identified: (1) moving beyond the focus on overall efficacy to understand specific therapeutic processes targeting voices, (2) better targeting psychological processes associated with voices such as trauma, cognitive mechanisms, and personal recovery, (3) more focused measurement of the intended outcomes of therapy, (4) understanding individual differences among voice hearers, (5) extending beyond a focus on voices and schizophrenia into other populations and sensory modalities, and (6) shaping interventions for service implementation. PMID:24936081

  16. From classic to current: a look back on attention research in the American Journal of Psychology.

    Science.gov (United States)

    Mounts, Jeffrey R W

    2012-01-01

    This review examines attention research appearing in The American Journal of Psychology over the journal's rich 125-year history. In particular, the review examines studies focused on selective attention's role in modulating the influence of distraction and the methods used to capture the nature of selective attention. Special attention is given to classic articles by Treisman (1964a, 1964b), Neisser (1963), and Eriksen and Rohrbaugh (1970), whose methods and results are examined in detail in light of current theory and research in selective attention.

  17. FES in Europe and beyond: Current Translational Research

    Directory of Open Access Journals (Sweden)

    Christine Azevedo Coste

    2016-12-01

    Full Text Available Capacity of adult neural and muscle tissues to respond to external Electrical Stimulation (ES is the biological basis for the development and implementation of mobility impairment physiotherapy protocols and of related assistive technologies, e.g, Functional Electrical Stimulation (FES. All body tissues, however, respond to electrical stimulation and, indeed, the most successful application of FES is electrical stimulation of the heart to revert or limit effects of arrhythmias (Pace-makers and Defibrillators. Here, we list and discuss results of FES current research activities, in particular those presented at 2016 Meetings: the PaduaMuscleDays, the Italian Institute of Myology Meeting, the 20th International Functional Electrical Stimulation Society (IFESS conference held in Montpellier and the Vienna Workshop on FES. Several papers were recently e-published in the European Journal of Translational Myology as reports of meeting presentations. All the events and publications clearly show that FES research in Europe and beyond is alive and promisses translation of results into clinical management of a very large population of persons with deficiencies.

  18. Current Status of Periodic Safety Review of HANARO Research Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Minjin; Ahn, Guk-Hoon; Lee, Choong Sung [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2016-10-15

    A PSR for a research reactor became a legal requirement as the Nuclear Safety Act was amended and came into effect in 2014. This paper describes the current status and methodology of the first Periodic Safety Review (PSR) of HANARO that is being performed. The legal requirements, work plan, and process of implementing a PSR are described. Because this is the first PSR for a research reactor, it is our understating that the operating organization and regulatory body should communicate well with each other to complete the PSR in a timely manner. The first PSR of HANARO is under way. In order to achieve a successful result, activities of the operation organization such as scheduling, maintaining consistency in input data for review, and reviewing the PSR reports that will require intensive resources should be well planned. This means the operating organization needs to incorporate appropriate measures to ensure the transfer of knowledge and expertise arising from the PSR via a contractor to the operation organization. It is desirable for the Regulatory Body to be involved in all stage of the PSR to prevent any waste of resources and minimize the potential for a reworking of the PSR and the need for an additional assessment and review as recommended by foreign experts.

  19. Online Facebook Focus Group Research of Hard-to-Reach Participants

    Directory of Open Access Journals (Sweden)

    Anastasia Aldelina Lijadi

    2015-12-01

    Full Text Available Conducting discovery-oriented qualitative research about the life experiences of hard-to-reach individuals posed several challenges for recruiting participants and collecting rich textual data. In a study pertaining the experiences of Third Culture Kids (TCKs, we explored the benefits of the social media, such as Facebook as a platform to collect data. TCKs are individuals who define their sense of belonging to the third culture trailing their parents moving across borders during their developmental years. Adult TCKs live in many different countries, and accessing and interviewing respondents could be a difficult and costly endeavor. In this article, the authors share their experience conducting online, asynchronous focus groups using a Facebook platform. We reflect upon the process of setting up a secret Facebook focus group for research purposes, recruiting participants, rapport building between facilitator and participants, monitoring and keeping track of participants’ responses, and the dynamics emerging within an online focus group. We also discuss the novelty, limitations, and benefits of the Facebook focus group as an emerging mode for collecting qualitative data from hard-to-reach participants.

  20. Future Deltas Utrecht University research focus area: towards sustainable management of sinking deltas

    Science.gov (United States)

    Stouthamer, E.; van Asselen, S.

    2015-11-01

    Deltas are increasingly under pressure from human impact and climate change. To deal with these pressures that threat future delta functioning, we need to understand interactions between physical, biological, chemical and social processes in deltas. This requires an integrated approach, in which knowledge on natural system functioning is combined with knowledge on spatial planning, land and water governance and legislative frameworks. In the research focus area Future Deltas of Utrecht University an interdisciplinary team from different research groups therefore works together. This allows developing integrated sustainable and resilient delta management strategies, which is urgently needed to prevent loss of vital delta services.

  1. The use of Facebook for virtual asynchronous focus groups in qualitative research.

    Science.gov (United States)

    Biedermann, Narelle

    2018-02-01

    The Internet and the development of more user-engaging applications have opened a whole new world for researchers as a means of recruitment and data collection source. This paper describes the methodological approach of a research study that explored the experiences of Australian military spouses who packed up their family and home to accompany their spouse on an overseas posting. The study used Facebook as a recruitment tool and then as a data source through the conduct of an asynchronous virtual focus group. This paper outlines the advantages and disadvantages of this unique data source as a means of capturing the voices of a hard-to-reach population.

  2. Current research trend on urban sewerage system in China

    Science.gov (United States)

    Ning, Yun-Fang; Dong, Wen-Yi; Lin, Lu-Sheng; Zhang, Qian

    2017-03-01

    The research emphasis has always been on sewerage treatment technology in China, though urban drainage system has gained little attention. In the context of urban drainage system and the problem associated with rain, the focus is still mainly toward the simple “emissions”. While the relationship between conservation and utilization of rainwater resources and urban ecology are popular, the relationship between rainwater discharge and non-point source pollution are often neglected. The reasonable choice of sewerage system is dependent on the collection and discharge of urban sewerage, the applicability and economic benefits, along with the ability to meet the water quality requirements and environmental protection. This paper analyzes and summarizes the development of urban drainage system in china, and introduces different drainage forms. The choice of drainage system should be based on the overall planning of the city, environmental protection requirements, the local natural conditions and water conditions, urban sewerage and water quality, the original drainage facilities, and local climatic conditions. It must be comprehensive to meet the environmental protection requirements, through technical and economic comparison.

  3. Health effects research and regulation of diesel exhaust: an historical overview focused on lung cancer risk.

    Science.gov (United States)

    Hesterberg, Thomas W; Long, Christopher M; Bunn, William B; Lapin, Charles A; McClellan, Roger O; Valberg, Peter A

    2012-06-01

    The mutagenicity of organic solvent extracts from diesel exhaust particulate (DEP), first noted more than 55 years ago, initiated an avalanche of diesel exhaust (DE) health effects research that now totals more than 6000 published studies. Despite an extensive body of results, scientific debate continues regarding the nature of the lung cancer risk posed by inhalation of occupational and environmental DE, with much of the debate focused on DEP. Decades of scientific scrutiny and increasingly stringent regulation have resulted in major advances in diesel engine technologies. The changed particulate matter (PM) emissions in "New Technology Diesel Exhaust (NTDE)" from today's modern low-emission, advanced-technology on-road heavy-duty diesel engines now resemble the PM emissions in contemporary gasoline engine exhaust (GEE) and compressed natural gas engine exhaust more than those in the "traditional diesel exhaust" (TDE) characteristic of older diesel engines. Even with the continued publication of epidemiologic analyses of TDE-exposed populations, this database remains characterized by findings of small increased lung cancer risks and inconsistent evidence of exposure-response trends, both within occupational cohorts and across occupational groups considered to have markedly different exposures (e.g. truckers versus railroad shopworkers versus underground miners). The recently published National Institute for Occupational Safety and Health (NIOSH)-National Cancer Institute (NCI) epidemiologic studies of miners provide some of the strongest findings to date regarding a DE-lung cancer association, but some inconsistent exposure-response findings and possible effects of bias and exposure misclassification raise questions regarding their interpretation. Laboratory animal studies are negative for lung tumors in all species, except for rats under lifetime TDE-exposure conditions with durations and concentrations that lead to "lung overload." The species specificity of the

  4. Health effects research and regulation of diesel exhaust: an historical overview focused on lung cancer risk

    Science.gov (United States)

    Hesterberg, Thomas W.; Long, Christopher M.; Bunn, William B.; Lapin, Charles A.; McClellan, Roger O.; Valberg, Peter A.

    2012-01-01

    The mutagenicity of organic solvent extracts from diesel exhaust particulate (DEP), first noted more than 55 years ago, initiated an avalanche of diesel exhaust (DE) health effects research that now totals more than 6000 published studies. Despite an extensive body of results, scientific debate continues regarding the nature of the lung cancer risk posed by inhalation of occupational and environmental DE, with much of the debate focused on DEP. Decades of scientific scrutiny and increasingly stringent regulation have resulted in major advances in diesel engine technologies. The changed particulate matter (PM) emissions in “New Technology Diesel Exhaust (NTDE)” from today's modern low-emission, advanced-technology on-road heavy-duty diesel engines now resemble the PM emissions in contemporary gasoline engine exhaust (GEE) and compressed natural gas engine exhaust more than those in the “traditional diesel exhaust” (TDE) characteristic of older diesel engines. Even with the continued publication of epidemiologic analyses of TDE-exposed populations, this database remains characterized by findings of small increased lung cancer risks and inconsistent evidence of exposure-response trends, both within occupational cohorts and across occupational groups considered to have markedly different exposures (e.g. truckers versus railroad shopworkers versus underground miners). The recently published National Institute for Occupational Safety and Health (NIOSH)-National Cancer Institute (NCI) epidemiologic studies of miners provide some of the strongest findings to date regarding a DE-lung cancer association, but some inconsistent exposure-response findings and possible effects of bias and exposure misclassification raise questions regarding their interpretation. Laboratory animal studies are negative for lung tumors in all species, except for rats under lifetime TDE-exposure conditions with durations and concentrations that lead to'lung overload."The species specificity

  5. Current research and potential applications of the Concealed Information Test: An overview

    Directory of Open Access Journals (Sweden)

    Gershon eBen-Shakhar

    2012-09-01

    Full Text Available Research interest in psychophysiological detection of deception has significantly increased since the September 11 terror attack in the USA. In particular, the Concealed Information Test (CIT, designed to detect memory traces that can connect suspects to a certain crime, has been extensively studied. In this paper I will briefly review several psychophysiological detection paradigms that have been studied, with a focus on the CIT. The theoretical background of the CIT, its strength and weaknesses, its potential applications as well as research finings related to its validity, (based on a recent mata-analytic study, will be discussed. Several novel research directions, with a focus on factors that may affect CIT detection in realistic settings (e.g., memory for crime details; the effect of emotional stress during crime execution will be described. Additionally, research focusing on mal-intentions and attempts to detect terror networks using information gathered from groups of suspects using both the standard CIT and the searching CIT will be reviewed. Finally, implications of current research to the actual application of the CIT will be discussed and several recommendations that can enhance the use of the CIT will be made.

  6. Public health services and systems research: current state of finance research.

    Science.gov (United States)

    Ingram, Richard C; Bernet, Patrick M; Costich, Julia F

    2012-11-01

    There is a growing recognition that the US public health system should strive for efficiency-that it should determine the optimal ways to utilize limited resources to improve and protect public health. The field of public health finance research is a critical part of efforts to understand the most efficient ways to use resources. This article discusses the current state of public health finance research through a review of public health finance literature, chronicles important lessons learned from public health finance research to date, discusses the challenges faced by those seeking to conduct financial research on the public health system, and discusses the role of public health finance research in relation to the broader endeavor of Public Health Services and Systems Research.

  7. Where Is Current Research on Blockchain Technology?-A Systematic Review.

    Directory of Open Access Journals (Sweden)

    Jesse Yli-Huumo

    Full Text Available Blockchain is a decentralized transaction and data management technology developed first for Bitcoin cryptocurrency. The interest in Blockchain technology has been increasing since the idea was coined in 2008. The reason for the interest in Blockchain is its central attributes that provide security, anonymity and data integrity without any third party organization in control of the transactions, and therefore it creates interesting research areas, especially from the perspective of technical challenges and limitations. In this research, we have conducted a systematic mapping study with the goal of collecting all relevant research on Blockchain technology. Our objective is to understand the current research topics, challenges and future directions regarding Blockchain technology from the technical perspective. We have extracted 41 primary papers from scientific databases. The results show that focus in over 80% of the papers is on Bitcoin system and less than 20% deals with other Blockchain applications including e.g. smart contracts and licensing. The majority of research is focusing on revealing and improving limitations of Blockchain from privacy and security perspectives, but many of the proposed solutions lack concrete evaluation on their effectiveness. Many other Blockchain scalability related challenges including throughput and latency have been left unstudied. On the basis of this study, recommendations on future research directions are provided for researchers.

  8. Where Is Current Research on Blockchain Technology?-A Systematic Review.

    Science.gov (United States)

    Yli-Huumo, Jesse; Ko, Deokyoon; Choi, Sujin; Park, Sooyong; Smolander, Kari

    2016-01-01

    Blockchain is a decentralized transaction and data management technology developed first for Bitcoin cryptocurrency. The interest in Blockchain technology has been increasing since the idea was coined in 2008. The reason for the interest in Blockchain is its central attributes that provide security, anonymity and data integrity without any third party organization in control of the transactions, and therefore it creates interesting research areas, especially from the perspective of technical challenges and limitations. In this research, we have conducted a systematic mapping study with the goal of collecting all relevant research on Blockchain technology. Our objective is to understand the current research topics, challenges and future directions regarding Blockchain technology from the technical perspective. We have extracted 41 primary papers from scientific databases. The results show that focus in over 80% of the papers is on Bitcoin system and less than 20% deals with other Blockchain applications including e.g. smart contracts and licensing. The majority of research is focusing on revealing and improving limitations of Blockchain from privacy and security perspectives, but many of the proposed solutions lack concrete evaluation on their effectiveness. Many other Blockchain scalability related challenges including throughput and latency have been left unstudied. On the basis of this study, recommendations on future research directions are provided for researchers.

  9. Where Is Current Research on Blockchain Technology?—A Systematic Review

    Science.gov (United States)

    Yli-Huumo, Jesse; Ko, Deokyoon; Park, Sooyong; Smolander, Kari

    2016-01-01

    Blockchain is a decentralized transaction and data management technology developed first for Bitcoin cryptocurrency. The interest in Blockchain technology has been increasing since the idea was coined in 2008. The reason for the interest in Blockchain is its central attributes that provide security, anonymity and data integrity without any third party organization in control of the transactions, and therefore it creates interesting research areas, especially from the perspective of technical challenges and limitations. In this research, we have conducted a systematic mapping study with the goal of collecting all relevant research on Blockchain technology. Our objective is to understand the current research topics, challenges and future directions regarding Blockchain technology from the technical perspective. We have extracted 41 primary papers from scientific databases. The results show that focus in over 80% of the papers is on Bitcoin system and less than 20% deals with other Blockchain applications including e.g. smart contracts and licensing. The majority of research is focusing on revealing and improving limitations of Blockchain from privacy and security perspectives, but many of the proposed solutions lack concrete evaluation on their effectiveness. Many other Blockchain scalability related challenges including throughput and latency have been left unstudied. On the basis of this study, recommendations on future research directions are provided for researchers. PMID:27695049

  10. Respiratory sensitization and allergy: Current research approaches and needs

    International Nuclear Information System (INIS)

    Boverhof, Darrell R.; Billington, Richard; Gollapudi, B. Bhaskar; Hotchkiss, John A.; Krieger, Shannon M.; Poole, Alan; Wiescinski, Connie M.; Woolhiser, Michael R.

    2008-01-01

    There are currently no accepted regulatory models for assessing the potential of a substance to cause respiratory sensitization and allergy. In contrast, a number of models exist for the assessment of contact sensitization and allergic contact dermatitis (ACD). Research indicates that respiratory sensitizers may be identified through contact sensitization assays such as the local lymph node assay, although only a small subset of the compounds that yield positive results in these assays are actually respiratory sensitizers. Due to the increasing health concerns associated with occupational asthma and the impending directives on the regulation of respiratory sensitizers and allergens, an approach which can identify these compounds and distinguish them from contact sensitizers is required. This report discusses some of the important contrasts between respiratory allergy and ACD, and highlights several prominent in vivo, in vitro and in silico approaches that are being applied or could be further developed to identify compounds capable of causing respiratory allergy. Although a number of animal models have been used for researching respiratory sensitization and allergy, protocols and endpoints for these approaches are often inconsistent, costly and difficult to reproduce, thereby limiting meaningful comparisons of data between laboratories and development of a consensus approach. A number of emerging in vitro and in silico models show promise for use in the characterization of contact sensitization potential and should be further explored for their ability to identify and differentiate contact and respiratory sensitizers. Ultimately, the development of a consistent, accurate and cost-effective model will likely incorporate a number of these approaches and will require effective communication, collaboration and consensus among all stakeholders

  11. Distributed and grid computing projects with research focus in human health.

    Science.gov (United States)

    Diomidous, Marianna; Zikos, Dimitrios

    2012-01-01

    Distributed systems and grid computing systems are used to connect several computers to obtain a higher level of performance, in order to solve a problem. During the last decade, projects use the World Wide Web to aggregate individuals' CPU power for research purposes. This paper presents the existing active large scale distributed and grid computing projects with research focus in human health. There have been found and presented 11 active projects with more than 2000 Processing Units (PUs) each. The research focus for most of them is molecular biology and, specifically on understanding or predicting protein structure through simulation, comparing proteins, genomic analysis for disease provoking genes and drug design. Though not in all cases explicitly stated, common target diseases include research to find cure against HIV, dengue, Duchene dystrophy, Parkinson's disease, various types of cancer and influenza. Other diseases include malaria, anthrax, Alzheimer's disease. The need for national initiatives and European Collaboration for larger scale projects is stressed, to raise the awareness of citizens to participate in order to create a culture of internet volunteering altruism.

  12. Current Insights into Research on Rice stripe virus

    Directory of Open Access Journals (Sweden)

    Won Kyong Cho

    2013-09-01

    Full Text Available Rice stripe virus (RSV is one of the most destructive viruses of rice, and greatly reduces rice production in China, Japan, and Korea, where mostly japonica cultivars of rice are grown. RSV is transmitted by the small brown plant-hopper (SBPH in a persistent and circulative-propagative manner. Several methods have been developed for detection of RSV, which is composed of four single-stranded RNAs that encode seven proteins. Genome sequence data and comparative phylogenetic analysis have been used to identify the origin and diversity of RSV isolates. Several rice varieties resistant to RSV have been selected and QTL analysis and fine mapping have been intensively performed to map RSV resistance loci or genes. RSV genes have been used to generate several genetically modified transgenic rice plants with RSV resistance. Recently, genome-wide transcriptome analyses and deep sequencing have been used to identify mRNAs and small RNAs involved in RSV infection; several rice host factors that interact with RSV proteins have also been identified. In this article, we review the current statues of RSV research and propose integrated approaches for the study of interactions among RSV, rice, and the SBPH.

  13. Sleep disturbance due to noise: Current issues and future research

    Directory of Open Access Journals (Sweden)

    Ken Hume

    2010-01-01

    Full Text Available There is growing interest in carrying out further research to understand and reduce the impact of aircraft noise on airport neighborhood in anticipation of the projected substantial increase in global aviation. Soundscapes provide new analytical methods and a broader, more comprehensive appreciation of the aural environment, which may have a useful role in understanding noise-induced sleep disturbance and annoyance. Current noise metrics like Leq do not provide a common language to report noise environment to residents, which is a key obstacle to effective noise management and acceptance. Non-auditory effects complicate the production of consistent dose-response functions for aircraft noise affecting sleep and annoyance. There are various end-points that can be chosen to assess the degree of sleep disturbance, which has detracted from the clarity of results that has been communicated to wider audiences. The World Health Organization (WHO-Europe has produced Night Noise Guidelines for Europe, which act as a clear guide for airports and planners to work towards. Methodological inadequacies and the need for simpler techniques to record sleep will be considered with the exciting potential to greatly increase cost-effective field data acquisition, which is needed for large scale epidemiological studies

  14. Linking research and education: an undergraduate research apprenticeship focusing on geologic and ecological impacts of the Elwha River Restoration

    Science.gov (United States)

    Ogston, A. S.; Eidam, E.; Webster, K. L.; Hale, R. P.

    2016-02-01

    Experiential learning is becoming well-rooted in undergraduate curriculum as a means of stimulating interest in STEM fields, and of preparing students for future careers in scientific research and communication. To further these goals in coastal sciences, an intensive, research-focused course was developed at the UW Friday Harbor Labs. The course revolved around an active NSF-funded research project concerning the highly publicized Elwha River Restoration project. Between 2008 and 2014, four groups of research "apprentices" spent their academic quarter in residence at a small, coastal marine lab in a learning environment that integrated interdisciplinary lectures, workshops on data analysis and laboratory methods, and the research process from proposal to oceanographic research cruise to publication. This environment helped students gain important skills in fieldwork planning and execution, laboratory and digital data analyses, and manuscript preparation from start to finish—all while elevating their knowledge of integrated earth science topics related to a coastal restoration project. Students developed their own research proposals and pursued their individual interests within the overall research topic, thereby expanding the overall breadth of the NSF-funded research program. The topics of student interest were often beyond the researcher's expertise, which ultimately led to more interdisciplinary findings beyond the quarter-long class. This also provided opportunities for student creativity and leadership, and for collaboration with fellow course participants and with students from many other disciplines in residence at the marine lab. Tracking the outcomes of the diverse student group undertaking this program indicates that these undergraduate (and post-bac) students are generally attending graduate school at a high rate, and launching careers in education, coastal management, and other STEM fields.

  15. Current thinking in qualitative research: evidence-based practice, moral philosophies, and political struggle.

    Science.gov (United States)

    Papadimitriou, Christina; Magasi, Susan; Frank, Gelya

    2012-01-01

    In this introduction to the special issue on current thinking in qualitative research and occupational therapy and science, the authors focus on the importance of rigorous qualitative research to inform occupational therapy practice. The authors chosen for this special issue reflect a "second generation of qualitative researchers" who are critical, theoretically sophisticated, methodologically productive, and politically relevant to show that working with disabled clients is political work. Three themes emerged across the articles included in this special issue: (1) recognizing and addressing social justice issues; (2) learning from clients' experiences; and (3) critically reframing occupational therapy's role. These themes can inform occupational therapy practice, research, and education to reflect a more client-centered and politically engaging approach. Copyright 2012, SLACK Incorporated.

  16. Indicators of national focus of the research published by Public Health journals edited in Brazil.

    Science.gov (United States)

    Packer, Abel Laerte

    2015-07-01

    This report presents a set of bibliometric indicators and statistics which explain the high level of production of articles on research in public and collective health in Brazil which are published in the main nationally edited journals in the field. The predominance of publications in the Portuguese language by Brazilian authors results in a lower impact in terms of citations received as measured by the bibliometric indexes Scimago/Scopus and JCR/WoS. These bibliometric indexes are used to measure the production and performance of research and journals. Nevertheless, the performance of these same journals stands out in SciELO, and is competitive internationally in the broader context of Google Scholar Metrics. The challenge faced by journals in Brazil is developing and applying editorial policies for the valuation of research with a national focus, and its internationalization.

  17. Shifting the focus from quantitative to qualitative exercise characteristics in exercise and cognition research.

    Science.gov (United States)

    Pesce, Caterina

    2012-12-01

    In exercise and cognition research, few studies have investigated whether and how the qualitative aspects of physical exercise may impact cognitive performance in the short or long term. This commentary, after recalling the evidence on the "dose-response" relationship, shifts the focus to intersections between different research areas that are proposed to shed light on how qualitative exercise characteristics can be used to obtain cognitive benefits. As concerns the acute exercise area, this commentary highlights the applied relevance of developmental and aging studies investigating the effects of exercise bouts differing in movement task complexity and cognitive demands. As regards the chronic exercise area, potential links to research on cognitive expertise in sport, functional ability in aging, and life skills training during development are discussed. "Gross-motor cognitive training" is proposed as a key concept with relevant implications for intervention strategies in childhood and older adulthood.

  18. Integrating utilization-focused evaluation with business process modeling for clinical research improvement.

    Science.gov (United States)

    Kagan, Jonathan M; Rosas, Scott; Trochim, William M K

    2010-10-01

    New discoveries in basic science are creating extraordinary opportunities to design novel biomedical preventions and therapeutics for human disease. But the clinical evaluation of these new interventions is, in many instances, being hindered by a variety of legal, regulatory, policy and operational factors, few of which enhance research quality, the safety of study participants or research ethics. With the goal of helping increase the efficiency and effectiveness of clinical research, we have examined how the integration of utilization-focused evaluation with elements of business process modeling can reveal opportunities for systematic improvements in clinical research. Using data from the NIH global HIV/AIDS clinical trials networks, we analyzed the absolute and relative times required to traverse defined phases associated with specific activities within the clinical protocol lifecycle. Using simple median duration and Kaplan-Meyer survival analysis, we show how such time-based analyses can provide a rationale for the prioritization of research process analysis and re-engineering, as well as a means for statistically assessing the impact of policy modifications, resource utilization, re-engineered processes and best practices. Successfully applied, this approach can help researchers be more efficient in capitalizing on new science to speed the development of improved interventions for human disease.

  19. Summary of current research on Central Asian vortex

    Directory of Open Access Journals (Sweden)

    Lian-Mei YANG

    2017-03-01

    Full Text Available The Central Asian vortex (CAV is an important synoptic-scale system that causes rainstorms, short-term heavy precipitation, hail, and sustained low temperatures in Xinjiang. This paper summarizes the current research conducted on the CAV since the 1960s. The objective definition of the CAV has been revised and a deep and shallow CAV classification proposed. Two high-frequency areas of deep CAV activity are the Kazakhstan hills (Sayan mountains and the eastern area of the Aral Sea (Tashkent; events mostly occur in summer and 40% cause strong rainfall. In addition, two high-frequency activity areas of the shallow CAV are located in the west and south of the Pamirs Plateau and mostly occur in spring; 23.2% of occurrences cause strong rainfall. The western and eastern water vapor transport relates to westerlies and a strong low-level easterly jet stream (LLEJ extending from Gansu to Xinjiang, respectively, and water vapor over the Tibetan Plateau transports even more northwards and enters Xinjiang. The deep CAV has an obvious cold core structure down to 300 hPa. The conversion terms from eddy available potential energy (AE to eddy kinetic energy (KE and eddy kinetic energy inflow (BKE from the open atmospheric region boundaries are the main sources of KE which cause rapid development of the CAV. The anomalous anti-cyclone center over the northeast Atlantic is the fountain of Rossby wave energy dispersion; Rossby waves propagate from the northeast Atlantic to eastern Europe (Urals (EEU, and then continuously propagate to Central Asia causing development of the CAV. The CAV requires further study to characterize the meso-scale system structure and evolution characteristics. In addition, physical modeling of the severe convective weather occurring under the CAV is required to determine the critical impacts of this severe convective weather and enable forecasting and early-warning indexes.

  20. Research Activity and Infrastructure of Korea Polar Research Institute: Current and Future Perspectives

    Science.gov (United States)

    Jin, D.; Kim, S.; Lee, H.

    2011-12-01

    The Korea Polar Research Institute (KOPRI) opened the Antarctic King Sejong research station in 1988 at the King George Island off the Antarctic Peninsula and started the polar research mainly in the fields of biology and geology with some atmosphere observations. To extend the view of polar research, the KOPRI opened the Arctic Dasan research station at Ny-Alesund, Spitsbergen Island in 2002 and has studied the rapid climate change diagnostics and some microbiological observation. The KOPRI is now expanding the Arctic research into Alaska and Canada under the international collaboration, and planning to outreach to Russia to monitor the change in permafrost and to understand its impact on global warming. To deepen the views of polar research including the ice covered oceans in both poles, the ice-breaking vessel, the ARAON of about 7000 ton, was launched recently and successfully finished the Arctic and Antarctic cruises for research activity on all perspectives of ocean sciences and support for the King Sejong station. The KOPRI is now building another Antarctic research station, called Jangbogo, at the Terra Nova Bay off the Ross Sea and plan to open the station at the March of 2014. By building the second Antarctic station together with the ARAON, the KOPRI will focus its research on understanding the rapid climate change in west Antarctica such as to monitor the calving of the Larsen Ice shelf, rapid melting of Pine Island Glacier, and upper atmosphere, to study the sea ice and ecosystem change in the Amundsen Sea and the role of the southern annular mode in the west Antarctic warming, upper atmosphere and climate change, to reconstruct paleoclimate records from ice and sediment cores.

  1. Simulative research on reverse current in magnetically insulated coaxial diode

    Directory of Open Access Journals (Sweden)

    Danni Zhu

    2017-10-01

    Full Text Available The reverse current tends to occur in the transition region of the guiding magnetic field in a magnetically insulated coaxial diode (MICD. Influence of the guiding magnetic field on characteristics of the MICD especially on the reverse current is studied by the particle-in-cell (PIC simulation in this paper. The reverse current is confirmed to be irrelevant with the guiding magnetic field strength. However, the reverse current is clarified quantitatively to depend on the electric and magnetic field distribution in the upstream of the cathode tip. As the MICD has been widely employed in microwave tubes, a simple approach to suppress the reverse current on the premise of little change of the original diode is valuable and thus proposed. The optimum matching point between the cathode and the magnetic field is selected in consideration of the entrance depth tolerance, the diode impedance discrepancy and the reverse current coefficient.

  2. Does Contralateral Delay Activity Reflect Working Memory Storage or the Current Focus of Spatial Attention within Visual Working Memory?

    Science.gov (United States)

    Berggren, Nick; Eimer, Martin

    2016-12-01

    During the retention of visual information in working memory, event-related brain potentials show a sustained negativity over posterior visual regions contralateral to the side where memorized stimuli were presented. This contralateral delay activity (CDA) is generally believed to be a neural marker of working memory storage. In two experiments, we contrasted this storage account of the CDA with the alternative hypothesis that the CDA reflects the current focus of spatial attention on a subset of memorized items set up during the most recent encoding episode. We employed a sequential loading procedure where participants memorized four task-relevant items that were presented in two successive memory displays (M1 and M2). In both experiments, CDA components were initially elicited contralateral to task-relevant items in M1. Critically, the CDA switched polarity when M2 displays appeared on the opposite side. In line with the attentional activation account, these reversed CDA components exclusively reflected the number of items that were encoded from M2 displays, irrespective of how many M1 items were already held in working memory. On trials where M1 and M2 displays were presented on the same side and on trials where M2 displays appeared nonlaterally, CDA components elicited in the interval after M2 remained sensitive to a residual trace of M1 items, indicating that some activation of previously stored items was maintained across encoding episodes. These results challenge the hypothesis that CDA amplitudes directly reflect the total number of stored objects and suggest that the CDA is primarily sensitive to the activation of a subset of working memory representations within the current focus of spatial attention.

  3. Medical research and audit skills training for undergraduates: an international analysis and student-focused needs assessment.

    Science.gov (United States)

    2018-01-01

    Interpreting, performing and applying research is a key part of evidence-based medical practice, however, incorporating these within curricula is challenging. This study aimed to explore current provision of research skills training within medical school curricula, provide a student-focused needs assessment and prioritise research competencies. A international, cross-sectional survey of final year UK and Irish medical students was disseminated at each participating university. The questionnaire investigated research experience, and confidence in the Medical Education in Europe (MEDINE) 2 consensus survey research competencies. Fully completed responses were received from 521 final year medical students from 32 medical schools (43.4% male, mean age 24.3 years). Of these, 55.3% had an additional academic qualification (49.5% Bachelor's degree), and 38.8% had been a named author on an academic publication. Considering audit and research opportunities and teaching experience, 47.2% reported no formal audit training compared with 27.1% who reported no formal research training. As part of their medical school course, 53.4% had not performed an audit, compared with 29.9% who had not participated in any clinical or basic science research. Nearly a quarter of those who had participated in research reported doing so outside of their medical degree course. Low confidence areas included selecting and performing the appropriate statistical test, selecting the appropriate research method, and critical appraisal. Following adjustment, several factors were associated with increased confidence including previous clinical research experience (OR 4.21, 2.66 to 6.81, Paudit skills training in the curriculum (OR 1.52, 1.03 to 2.26, P= 0.036) and research methods taught in a student selected component (OR 1.75, 1.21 to 2.54, P=0.003). Nearly one-third of students lacked formal training on undertaking research, and half of students lacked formal audit training and opportunities to

  4. Research on health equity in the SDG era: the urgent need for greater focus on implementation.

    Science.gov (United States)

    Rasanathan, Kumanan; Diaz, Theresa

    2016-12-09

    The tremendous increase in knowledge on inequities in health and their drivers in recent decades has not been matched by improvements in health inequities themselves, or by systematic evidence of what works to reduce health inequities. Within health equity research there is a skew towards diagnostic studies in comparison to intervention studies showing evidence of how interventions can reduce disparities. The lack of sufficient specific evidence on how to implement specific policies and interventions in specific contexts to reduce health inequities creates policy confusion and partly explains the lack of progress on health inequities. In the field of research on equity in health, the time has come to stop focusing so much energy on prevalence and pathways, and instead shift to proposing and testing solutions. Four promising approaches to do so are implementation research, natural experimental policy studies, research on buy-in by policy-makers to action on health inequities, and geospatial analysis. The case for action on social determinants and health inequities has well and truly been made. The community of researchers on health equity now need to turn their attention to supporting implementation efforts towards achievements of the Sustainable Development Goals and substantive reductions in health inequities.

  5. Focused transcranial direct current stimulation (tDCS) over the dorsolateral prefrontal cortex modulates specific domains of self-regulation.

    Science.gov (United States)

    Pripfl, Jürgen; Lamm, Claus

    2015-02-01

    Recent neuroscience theories suggest that different kinds of self-regulation may share a common psychobiological mechanism. However, empirical evidence for a domain general self-regulation mechanism is scarce. The aim of this study was to investigate whether focused anodal transcranial direct current stimulation (tDCS), facilitating the activity of the dorsolateral prefrontal cortex (dlPFC), acts on a domain general self-regulation mechanism and thus modulates both affective and appetitive self-regulation. Twenty smokers participated in this within-subject sham controlled study. Effects of anodal left, anodal right and sham tDCS over the dlPFC on affective picture appraisal and nicotine craving-cue appraisal were assessed. Anodal right tDCS over the dlPFC reduced negative affect in emotion appraisal, but neither modulated regulation of positive emotion appraisal nor of craving appraisal. Anodal left stimulation did not induce any significant effects. The results of our study show that domain specific self-regulation networks are at work in the prefrontal cortex. Focused tDCS modulation of this specific self-regulation network could probably be used during the first phase of nicotine abstinence, during which negative affect might easily result in relapse. These findings have implications for neuroscience models of self-regulation and are of relevance for the development of brain stimulation based treatment methods for neuropsychiatric disorders associated with self-regulation deficits. Copyright © 2014 Elsevier Ireland Ltd and the Japan Neuroscience Society. All rights reserved.

  6. Action research in rehabilitation with chronic stroke recovery: A case report with a focus on neural plasticity.

    Science.gov (United States)

    Pedersen, Malene; Bundgaard, Tina H; Zeeman, Peter; Jørgensen, Jørgen R; Sørensen, Peter M B; Berro, Hamza M; Larsson, Bodil W

    2016-06-27

    Chronic stroke patients are primarily referred to general rehabilitation, rather than to specific neurorehabilitation. Currently, there are no Danish clinical guidelines for chronic stroke, but recent research in neuroplasticity has contributed to possible rehabilitation interventions for these patients. The purpose of this project is to describe the use of a specialized neuroplastic approach in combination with an already existing training program. The project is designed as an action research project concerning four participants with chronic stroke. Through ten intervention, a neuroplastic focus has been added to their group training program including daily home training. Participants were tested before and after the intervention with MAS, DGI, 6MWT, SSQLS. All four participants improved their functional levels and their quality of life following the intervention. This report indicates that a specific neuroplastic focus in combination with action research has an impact on the participants with chronic stroke. However, there is still no clarity regarding what type of rehabilitation methods can be considered the most efficacious in promoting neuroplasticity. This case report serves as a pilot project for further studies of how to implement neuroplasticity in physical therapy.

  7. Current status of research on power-frequency electric and magnetic fields of research

    International Nuclear Information System (INIS)

    Anon.

    1991-01-01

    Recent scientific literature has suggested a number of possible human health effects which might be associated with exposure to power frequency electric and magnetic fields. Several authoritative reviews of this subject have been published. currently, the major uncertainty and the major research effort is directed to the issue of these fields and cancer. Therefore, this review will be limited to examining the evidence relating prolonged power-frequency electric and magnetic field exposure to cancer in human populations. This paper reports that the CIGRE expert Group has assessed the research literature in the following areas: epidemiological evidence, animal studies, cellular effects, knowledge of mechanisms

  8. The current status of utilization of research reactors in China

    International Nuclear Information System (INIS)

    Luzheng, Yuan

    2004-01-01

    Seminars on utilization of research reactors were held to enhance experience exchanging among institutes and universities in China. The status of CARR (China Advanced Research Reactor) project is briefly described. The progress in BNCT program in China is introduced. (author)

  9. Overview of current radon and radon daughter research at LBL

    International Nuclear Information System (INIS)

    1983-01-01

    This report provides a brief summary of radon and radon daughter research at Lawrence Berkeley Laboratory. The radon and radon daughter research program has two broad goals: (1) the study of sources of radon and its subsequent transport into houses, and (2) research on the behavior of radon daughters in indoor environments. Additional research effort is directed to several auxiliary areas, including development of instrumentation and monitoring techniques, studies of indoor air movement, and measurement and control of indoor particulate concentrations

  10. Current research work at the TRIGA reactor in Ljubljana

    International Nuclear Information System (INIS)

    Najzer, M.; Dimic, V.

    1978-01-01

    The research programmes at this TRIGA reactor cover quite broad and different research fields. They can be grouped in the following topics: reactor dynamics and operation, neutron activation analysis, solid state physics research, reactor dosimetry, radiography and fuel burn-up determination. In this presentation a short overview is given of those investigations which are not described in detail in separate papers

  11. The parameters of the current legal framework for health research ...

    African Journals Online (AJOL)

    2013-11-02

    Nov 2, 2013 ... Health research. Health research is defined very broadly in section 1 of the NHA, as ... national ethical guidelines issued by the Department of Health define research as a ... This definition suggests that section 71 only applies to studies ... nursing, rehabilitative, palliative, convalescent, preventative or other.

  12. Survey of current electric utility research in Canada

    International Nuclear Information System (INIS)

    1979-11-01

    Information on the research programs of eight Canadian electrical utilities and the Canadian Electrical Association has been compiled. Work done by the National Research Council of Canada is included, but the research done by Atomic Energy of Canada Ltd. is excluded. Projects in the area of nuclear power include work on heat transfer and fluid flow, waste management, materials, and corrosion. (L.L.)

  13. Current developments in environmental psychology : topics and researchers

    NARCIS (Netherlands)

    van der Werff, Ellen; Perlaviciute, Goda; Muinos, Gabriel

    2016-01-01

    The aim of this special issue is to bring the work of early-career researchers in environmental psychology to the spotlight. These young researchers come from different countries and cultures, have their own theoretical approaches and employ different research methods to increase knowledge on the

  14. Healthy lifestyle: Perceptions and attitudes of students (the results of a focus group research

    Directory of Open Access Journals (Sweden)

    Zh V Puzanova

    2014-12-01

    Full Text Available The article presents the results of the research conducted in December 2013 at the Peoples’ Friendship University of Russia with the method of focus groups. The study aimed at identification not only the differences in understanding healthy lifestyles among students and their attitudes to a healthy lifestyle, but also its components, obstacles for the realization and opportunities to overcome them. The focus group research was just another stage of the project aimed at studying health and healthy lifestyles as values and the characteristics of the formation and manifestation of a health-preserving behavior. Despite many opportunities to motivate a health-preserving behavior among students, we still see obstacles for its formation due to both social and cultural characteristics. The study revealed that the value of health at this stage of life is rather declarative: only a small percentage of respondents are fully aware of the necessity of a health-preserving behavior and do really adopt a healthy lifestyle. The basic factors influencing the formation of the healthy lifestyle among the youth are the family, social environment and mass media. The respondents, in particular, confirm the significant impact of their social circle on the commitment to the bad habits as well as to healthy hobbies. The main factors hindering the healthy lifestyles among students include lack of free time, welfare, Internet addiction, lack of sufficient motivation and self-organization.

  15. Family-Focused Therapy for Bipolar Disorder: Reflections on 30 Years of Research.

    Science.gov (United States)

    Miklowitz, David J; Chung, Bowen

    2016-09-01

    Family-focused therapy (FFT) is an evidence-based intervention for adults and children with bipolar disorder (BD) and their caregivers, usually given in conjunction with pharmacotherapy after an illness episode. The treatment consists of conjoint sessions of psychoeducation regarding bipolar illness, communication enhancement training, and problem-solving skills training. This paper summarizes over 30 years of research on FFT and family processes in BD. Across eight randomized controlled trials with adults and adolescents with BD, FFT and mood-stabilizing medications have been found to hasten recovery from mood episodes, reduce recurrences, and reduce levels of symptom severity compared to briefer forms of psychoeducation and medications over 1-2 years. Several studies indicate that the effects of FFT on symptom improvement are greater among patients with high-expressed emotion relatives. New research focuses on FFT as an early intervention for youth at risk for BD, neuroimaging as a means of evaluating treatment mechanisms, and progress in implementing FFT in community mental health settings. © 2016 Family Process Institute.

  16. Current approaches to treatments for schizophrenia spectrum disorders, part II: psychosocial interventions and patient-focused perspectives in psychiatric care

    Directory of Open Access Journals (Sweden)

    Chien WT

    2013-09-01

    functioning, and/or relapse rate. However, the comparative effects between these five approaches have not been well studied; thus, we are not able to clearly understand the superiority of any of these interventions. With the exception of patient relapse, the longer-term (eg, >2 years effects of these approaches on most psychosocial outcomes are not well-established among these patients. Despite the fact that patients' perspectives on treatment and care have been increasingly concerned, not many studies have evaluated the effect of interventions on this perspective, and where they did, the findings were inconclusive. To conclude, current approaches to psychosocial interventions for schizophrenia have their strengths and weaknesses, particularly indicating limited evidence on long-term effects. To improve the longer-term outcomes of people with schizophrenia, future treatment strategies should focus on risk identification, early intervention, person-focused therapy, partnership with family caregivers, and the integration of evidence-based psychosocial interventions into existing services. Keywords: schizophrenia, psychosocial intervention, patient-focused perspectives

  17. The social process of escalation: a promising focus for crisis management research

    Directory of Open Access Journals (Sweden)

    Bergström Johan

    2012-06-01

    Full Text Available Abstract Background This study identifies a promising, new focus for the crisis management research in the health care domain. After reviewing the literature on health care crisis management, there seems to be a knowledge-gap regarding organisational change and adaption, especially when health care situations goes from normal, to non-normal, to pathological and further into a state of emergency or crisis. Discussion Based on studies of escalating situations in obstetric care it is suggested that two theoretical perspectives (contingency theory and the idea of failure as a result of incomplete interaction tend to simplify the issue of escalation rather than attend to its complexities (including the various power relations among the stakeholders involved. However studying the process of escalation as inherently complex and social allows us to see the definition of a situation as normal or non-normal as an exercise of power in itself, rather than representing a putatively correct response to a particular emergency. Implications The concept of escalation, when treated this way, can help us further the analysis of clinical and institutional acts and competence. It can also turn our attention to some important elements in a class of social phenomenon, crises and emergencies, that so far have not received the attention they deserve. Focusing on organisational choreography, that interplay of potential factors such as power, professional identity, organisational accountability, and experience, is not only a promising focus for future naturalistic research but also for developing more pragmatic strategies that can enhance organisational coordination and response in complex events.

  18. Towards a new understanding of cohabitation: Insights from focus group research across Europe and Australia

    Directory of Open Access Journals (Sweden)

    Brienna Perelli-Harris

    2014-11-01

    Full Text Available Background: Across the industrialized world, more couples are living together without marrying. Although researchers have compared cohabitation cross-nationally using quantitative data, few have compared union formation using qualitative data. Objective: We use focus group research to compare social norms of cohabitation and marriage in Australia and nine countries in Europe. We explore questions such as: what is the meaning of cohabitation? To what extent is cohabitation indistinguishable from marriage, a prelude to marriage, or an alternative to being single? Are the meanings of cohabitation similar across countries? Methods: Collaborators conducted seven to eight focus groups in each country using a standardized guideline. They analyzed the discussions with bottom-up coding in each thematic area. They then collated the data in a standardized report. The first and second authors systematically analyzed the reports, with direct input from collaborators. Results: The results describe a specific picture of union formation in each country. However, three themes emerge in all focus groups: commitment, testing, and freedom. The pervasiveness of these concepts suggests that marriage and cohabitation have distinct meanings, with marriage representing a stronger level of commitment. Cohabitation is a way to test the relationship, and represents freedom. Nonetheless, other discourses emerged, suggesting that cohabitation has multiple meanings. Conclusions: This study illuminates how context shapes partnership formation, but also presents underlying reasons for the development of cohabitation. We find that the increase in cohabitation has not devalued the concept of marriage, but has become a way to preserve marriage as an ideal for long-term commitment.

  19. Outlining and dictating scientific manuscripts is a useful method for health researchers: A focus group interview.

    Science.gov (United States)

    Andresen, Kristoffer; Laursen, Jannie; Rosenberg, Jacob

    2018-01-01

    Young researchers may experience difficulties when writing scientific articles for publication in biomedical journals. Various methods may facilitate the writing process including outlining the paper before the actual writing and using dictation instead of writing the first draft. The aim of this study was to investigate the experiences and difficulties for young, experienced researchers when writing articles using a detailed outline and dictation of the first draft. We used qualitative focus group interviews and the study was reported according to the COnsolidated criteria for REporting Qualitative research guideline. Participants were sampled from a group of researchers participating in a writing retreat/course. The interviews were recorded on a digital recorder and transcribed. The text was analyzed according to content analysis and coded and condensed into themes and subthemes. Groups of participants were added until data saturation was reached. A total of 14 researchers participated (9 women and 5 men). Their clinical experience was median (range) of 6 (1-11) years since graduation from medical school. Two themes arose during the analyses of the data: "Process guidance with the outline as the map" and "arrival at dictation." The outline was used in the preparation phase leading up to the day of dictation and was used in collaboration with co-authors and supervisors. The participants found it to be a useful tool for preparing the manuscript and dictating their initial first full draft. Experienced young researchers found beneficial effects of using a structured outline to prepare for dictation of scientific articles. The outline was a tool that would develop in close collaboration with co-authors and mentors. With dictation, a full first draft of a manuscript can be produced in a few hours. Participants positively evaluated this structured and reproducible way of producing scientific articles.

  20. The parameters of the current legal framework for health research ...

    African Journals Online (AJOL)

    South African Journal of Bioethics and Law. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 6, No 2 (2013) >. Log in or Register to get access to full text downloads.

  1. Current hypotheses and research milestones in Alzheimer's disease

    National Research Council Canada - National Science Library

    Maccioni, Ricardo B; Perry, George

    2009-01-01

    .... This book contains 20 seminal chapters by authors with different views that in a multidisciplinary approach focus on the main issues of neuroanatomical, neuropathological, neuropsychological, neurological, and molecular biological aspects of AD. The idea for this collection arose during the preparation of the proceedings for the International Summit Meeting...

  2. Army Institutional Training: Current Status and Future Research

    Science.gov (United States)

    2010-03-01

    operative in the performance setting ( Thorndike & Woodworth, 1901). The principles theory suggests that that training should focus on the general...D. W. L. (2005). A meta-analytic review of behavior modeling training. Journal of Applied Psychology, 90, 692-709. 66 Thorndike , E. L

  3. The possible worlds of global health research: An ethics-focused discourse analysis.

    Science.gov (United States)

    Brisbois, Ben; Plamondon, Katrina

    2018-01-01

    Representations of the world enable global health research (GHR), discursively constructing sites in which studies can legitimately take place. Depoliticized portrayals of the global South frequently obscure messy legacies of colonialism and motivate technical responses to health problems with political and economic root causes. Such problematic representations of the world have not yet been rigorously examined in relation to global health ethics, a major site of scholarly effort towards GHR that promotes justice and fairness. We carried out a discourse analysis of four guidance documents relevant to the ethical practice of GHR, purposively selecting texts covering different genres (UN documents and journal articles) and prominent GHR foci (HIV and clinical trials). In light of increasing acknowledgement of the lessons Indigenous health scholarship holds for global health ethics, the four analyzed texts also included a set of principles developed to support Indigenous nation-building. Three of four documents featured global disparities as reasons for ethical caution. These inequalities appeared without explanation or causes, with generation of new scientific knowledge following as a logical response to such disparities. The fourth - Indigenous health-focused - document clearly identified 'colonialism' as a reason for both inequities in society, and related harmful research practices. Solutions to disparities in this text did not necessarily involve cutting-edge research, but focused instead on empowerment and responsiveness to community priorities and needs. These contrasting representations of the world were accomplished in ways that depended on texts' 'participants', or the people they represented; specific vocabularies or language usages; intertextual relationships to prior texts; and overall objectives or intentions of the author(s). Our results illustrate how ethics and other guidance documents serve as an important terrain for constructing, naturalizing or

  4. Current research in Radiation Biology and Biochemistry Division

    International Nuclear Information System (INIS)

    Tarachand, U.; Singh, B.B.

    1995-01-01

    The Radiation Biology and Biochemistry Division, Bhabha Atomic Research Centre, Bombay has been engaged in research in the frontier areas of (i) radiation biology related to tumour therapy and injury caused by free radicals; (ii) molecular basis of diseases of physiological origin; (iii) molecular aspects of chemical carcinogenesis and (iv) structure of genome and genome related functions. The gist of research and development activities carried out in the Division during the last two years are documented

  5. Current research in Radiation Biology and Biochemistry Division

    Energy Technology Data Exchange (ETDEWEB)

    Tarachand, U; Singh, B B [eds.; Bhabha Atomic Research Centre, Bombay (India). Radiation Biology and Biochemistry Div.

    1996-12-31

    The Radiation Biology and Biochemistry Division, Bhabha Atomic Research Centre, Bombay has been engaged in research in the frontier areas of (i) radiation biology related to tumour therapy and injury caused by free radicals; (ii) molecular basis of diseases of physiological origin; (iii) molecular aspects of chemical carcinogenesis and (iv) structure of genome and genome related functions. The gist of research and development activities carried out in the Division during the last two years are documented.

  6. Water reactor safety research program. A description of current and planned research

    International Nuclear Information System (INIS)

    1978-07-01

    The U.S. Nuclear Regulatory Commission (NRC) sponsors confirmatory safety research on lightwater reactors in support of the NRC regulatory program. The principal responsibility of the NRC, as implemented through its regulatory program is to ensure that public health, public safety, and the environment are adequately protected. The NRC performs this function by defining conditions for the use of nuclear power and by ensuring through technical review, audit, and follow-up that these conditions are met. The NRC research program provides technical information, independent of the nuclear industry, to aid in discharging these regulatory responsibilities. The objectives of NRC's research program are the following: (1) to maintain a confirmatory research program that supports assurance of public health and safety, and public confidence in the regulatory program, (2) to provide objectively evaluated safety data and analytical methods that meet the needs of regulatory activities, (3) to provide better quantified estimates of the margins of safety for reactor systems, fuel cycle facilities, and transportation systems, (4) to establish a broad and coherent exchange of safety research information with other Federal agencies, industry, and foreign organization. Current and planned research toward these goals is described

  7. Strategies for Sharing Scientific Research on Sea Level Rise: Suggestions from Stakeholder Focus Groups

    Science.gov (United States)

    DeLorme, D.; Hagen, S. C.; Stephens, S. H.

    2013-12-01

    This presentation reports results of focus groups with coastal resource managers on suggestions for effectively sharing sea level rise (SLR) scientific research with the public and other target audiences. The focus groups were conducted during three annual stakeholder workshops as an important and innovative component of an ongoing five-year multi-disciplinary NOAA-funded project, Ecological Effects of Sea Level Rise in the Northern Gulf of Mexico (EESLR-NGOM). The EESLR-NGOM project is assessing SLR risks to the natural and built environment along the Mississippi, Alabama, and Florida Panhandle coasts. The purpose was to engage stakeholders (e.g., coastal resource managers) in helping target, translate, and tailor the EESLR-NGOM project's scientific findings and emerging products so they are readily accessible, understandable, and useful. The focus groups provided insight into stakeholders' SLR informational and operational needs, solicited input on the project's products, and gathered suggestions for public communication and outreach. A total of three ninety-minute focus groups of between eight and thirteen participants each were conducted at annual workshops in Alabama, Florida, and Mississippi. The moderator asked a series of open-ended questions about SLR-related topics using an interview guide and encouraged participant interaction. All focus group audio-recordings were transcribed, and analyzed by carefully reading the 102 total pages of transcript data and identifying patterns and themes. Participants thought outreach about SLR impact and the EESLR-NGOM project scientific research/products was vital and acknowledged various communication challenges and opportunities. They identified three target audiences (local officials, general public, coastal resource managers themselves) that likely require different educational efforts and tools. Participants felt confident the EESLR-NGOM project products will benefit their resource planning and decision making and

  8. The current status of nuclear research reactor in Thailand

    Energy Technology Data Exchange (ETDEWEB)

    Sittichai, C; Kanyukt, R; Pongpat, P [Office of Atomic Energy for Peace, Bangkok (Thailand)

    1998-10-01

    Since 1962, the Thai Research Reactor has been serving for various kinds of activities i.e. the production of radioisotopes for medical uses and research and development on nuclear science and technology, for more than three decades. The existing reactor site should be abandoned and relocated to the new suitable site, according to Thai cabinet`s resolution on the 27 December 1989. The decommissioning project for the present reactor as well as the establishment of new nuclear research center were planned. This paper discussed the OAEP concept for the decommissioning programme and the general description of the new research reactor and some related information were also reported. (author)

  9. Enhancing Research Ethics Review Systems in Egypt: The Focus of an International Training Program Informed by an Ecological Developmental Approach to Enhancing Research Ethics Capacity.

    Science.gov (United States)

    Edwards, Hillary Anne; Hifnawy, Tamer; Silverman, Henry

    2015-12-01

    Recently, training programs in research ethics have been established to enhance individual and institutional capacity in research ethics in the developing world. However, commentators have expressed concern that the efforts of these training programs have placed 'too great an emphasis on guidelines and research ethics review', which will have limited effect on ensuring ethical conduct in research. What is needed instead is a culture of ethical conduct supported by national and institutional commitment to ethical practices that are reinforced by upstream enabling conditions (strong civil society, public accountability, and trust in basic transactional processes), which are in turn influenced by developmental conditions (basic freedoms of political freedoms, economic facilities, social opportunities, transparency guarantees, and protective security). Examining this more inclusive understanding of the determinants of ethical conduct enhances at once both an appreciation of the limitations of current efforts of training programs in research ethics and an understanding of what additional training elements are needed to enable trainees to facilitate national and institutional policy changes that enhance research practices. We apply this developmental model to a training program focused in Egypt to describe examples of such additional training activities. © 2014 John Wiley & Sons Ltd.

  10. Human memory research: Current hypotheses and new perspectives

    Directory of Open Access Journals (Sweden)

    Antônio Jaeger

    Full Text Available Abstract Research on human memory has increased significantly in the last few decades. Inconsistencies and controversies inherent to such research, however, are rarely articulated on published reports. The goal of the present article is to present and discuss a series of open questions related to major topics on human memory research that can be addressed by future research. The topics covered here are visual working memory, recognition memory, emotion and memory interaction, and methodological issues of false memories studies. Overall, the present work reveals a series of open questions and alternative analysis which could be useful for the process of hypothesis generation, and consequently for the design and implementation of future research on human memory.

  11. Mapping patterns of change in emotion-focused psychotherapy: Implications for theory, research, practice, and training.

    Science.gov (United States)

    Watson, Jeanne C

    2018-05-01

    An important objective in humanistic-experiential psychotherapies and particularly emotion-focused psychotherapy (EFT) is to map patterns of change. Effective mapping of the processes and pathways of change requires that in-session processes be linked to in-session resolutions, immediate post-session changes, intermediate outcome, final therapy outcome, and longer-term change. This is a challenging and long-term endeavour. Fine-grained descriptions of in-session processes that lead to resolution of specific interpersonal and intrapersonal issues linked with longer-term outcomes are the foundation of EFT, the process-experiential approach. In this paper, evidence in support of EFT as a treatment approach will be reviewed along with research on two mechanisms of change, viewed as central to EFT, clients' emotional processing and the therapeutic relationship conditions. The implications for psychotherapy research are discussed. Given the methodological constraints, there is a need for more innovative methodologies and strategies to investigate specific psychotherapy processes within and across different approaches to map patterns and mechanisms of change to enhance theory, research, practice, and training.

  12. Health Services Research and Health Economy - Quality Care Training in Gynaecology, with Focus On Gynaecological Oncology.

    Science.gov (United States)

    Lux, M P; Fasching, P A; Loehberg, C R; Jud, S M; Schrauder, M G; Bani, M R; Thiel, F C; Hack, C C; Hildebrandt, T; Beckmann, M W

    2011-12-01

    In the era of cost increases and reduced resources in the German healthcare system, the value of health services research and health economics is increasing more and more. Health services research attempts to develop concepts for the most effective ways to organise, manage, finance and deliver high-quality care and evaluates the implementation of these concepts with regard to daily routine conditions. Goals are the assessment of benefits and the economic advantages and disadvantages of new and established diagnostic methods, drugs and vaccines. Regarding these goals, it is clear that health services research goes hand in hand with health economics, which evaluates the benefits of diagnostic and therapeutic procedures in relation to the costs. Both scientific fields have focus principally on gynaecology and particularly on gynaecological oncology in Germany, as can be seen by numerous publications. These present several advantages compared with clinical trials - they uncover gaps in health care, question the material, staffing and consequently the financial resources required and they allow the estimation of value and the comparison of different innovations to identify the best options for our patients.

  13. Reprioritizing current research trends in medical education: a reflection on research activities in Saudi Arabia.

    Science.gov (United States)

    Obeidat, Akef S; Alhaqwi, Ali Ibrahim; Abdulghani, Hamza Mohammad

    2015-04-01

    There are numerous national efforts to determine and develop research priorities of medical education in Saudi Arabia. These priorities were first proposed in 2010 by "Dr Al-Khuli's Chair for Developing Medical Education in Saudi Arabia". The proposed priority domains were: curriculum, students, faculty, and quality assurance and accreditation. To investigate publications in medical education at the national and international levels in areas relating to these proposed priorities. Electronic search within PubMed database for papers relating to each domain of priority was conducted at national and international levels in the last three years, using the same keywords as the priority domains, but only confined to undergraduate medical education. Out of 3145 articles retrieved when searching with keyword as broad as "undergraduate medical curriculum" only 81 articles worldwide and 3 articles from Saudi Arabia were dealing with curriculum related issues as a whole. Further search on the sub-domains "effective strategies to manage undergraduate curriculum" and "undergraduate medical education models", resulted in the retrieval of few articles worldwide and none from Saudi Arabia. At the national level, there were 63 publications from Saudi Arabia that were either course (topic)-specific or could not be classified under the four domains specified by Dr Al-Khuli's Chair. Research activities in medical education in Saudi Arabia in the last 3 years showed diversity and lack of focus in the research priorities. Efforts of academic and research centers should continue to monitor and encourage these activities toward achieving the recommended priorities.

  14. Biodegradable magnesium-alloy stent:current situation in research

    International Nuclear Information System (INIS)

    Chen Hua; Zhao Xianxian

    2011-01-01

    In recent years, permanent metal stents are employed in the majority of interventional therapies; nevertheless, such kind of stents carries the problems of thrombosis and restenosis. Therefore, the biodegradable magnesium alloy stent has become the focus of attention. Theoretically, it has overcome the problems caused by permanent metal stents, so it is the development direction to use the biodegradable magnesium alloy in future. The authors believe that biodegradable magnesium alloy stents will be widely used in interventional procedures for many diseases. (authors)

  15. Incorporating current research into formal higher education settings using Astrobites

    Science.gov (United States)

    Sanders, Nathan E.; Kohler, Susanna; Faesi, Chris; Villar, Ashley; Zevin, Michael

    2017-10-01

    A primary goal of many undergraduate- and graduate-level courses in the physical sciences is to prepare students to engage in scientific research or to prepare students for careers that leverage skillsets similar to those used by research scientists. Even for students who may not intend to pursue a career with these characteristics, exposure to the context of applications in modern research can be a valuable tool for teaching and learning. However, a persistent barrier to student participation in research is familiarity with the technical language, format, and context that academic researchers use to communicate research methods and findings with each other: the literature of the field. Astrobites, an online web resource authored by graduate students, has published brief and accessible summaries of more than 1300 articles from the astrophysical literature since its founding in 2010. This article presents three methods for introducing students at all levels within the formal higher education setting to approaches and results from modern research. For each method, we provide a sample lesson plan that integrates content and principles from Astrobites, including step-by-step instructions for instructors, suggestions for adapting the lesson to different class levels across the undergraduate and graduate spectrum, sample student handouts, and a grading rubric.

  16. Italy. Report 1 [Marine Radioecology. Current Research and Future Scope

    International Nuclear Information System (INIS)

    Argiero, L.

    1967-01-01

    Present research programme: Studies on radioactive, biological and hydrographic characteristics of Tyrrhenian Sea; Organization of suitable control network of marine water and fauna: systematic measurement of present components of natural and artificial radioactivity of water, sediments and of the marine food chain techniques of sampling; analysis and measurement of particular radioisotopes in marine water. α, β, γ analysis of samples; γ spectrometry, research on 90 Sr and 137 Cs. Determination of concentration factors of radioisotopes which are responsible for contamination of principal components of the flora and fauna in the Tyrrhenian Sea; research of hydrographie factors influencing the distribution of marine radioactivity. Nuclide content of other organisms of the Tyrrhenian flora and fauna

  17. The small-animal radiation research platform (SARRP): dosimetry of a focused lens system

    Energy Technology Data Exchange (ETDEWEB)

    Deng Hua [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, Baltimore, MD (United States); Kennedy, Christopher W [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, Baltimore, MD (United States); Armour, Elwood [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, Baltimore, MD (United States); Tryggestad, Erik [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, Baltimore, MD (United States); Ford, Eric [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, Baltimore, MD (United States); McNutt, Todd [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, Baltimore, MD (United States); Jiang Licai [OSMIC Inc., 1900 Taylor Rd., Auburn Hills, MI (United States); Wong, John [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, Baltimore, MD (United States)

    2007-05-21

    A small animal radiation platform equipped with on-board cone-beam CT and conformal irradiation capabilities is being constructed for translational research. To achieve highly localized dose delivery, an x-ray lens is used to focus the broad beam from a 225 kVp x-ray tube down to a beam with a full width half maximum (FWHM) of approximately 1.5 mm in the energy range 40-80 keV. Here, we report on the dosimetric characteristics of the focused beam from the x-ray lens subsystem for high-resolution dose delivery. Using the metric of the average dose within a 1.5 mm diameter area, the dose rates at a source-to-surface distance (SSD) of 34 cm are 259 and 172 cGy min{sup -1} at 6 mm and 2 cm depths, respectively, with an estimated uncertainty of {+-}5%. The per cent depth dose is approximately 56% at 2 cm depth for a beam at 34 cm SSD.

  18. The small-animal radiation research platform (SARRP): dosimetry of a focused lens system.

    Science.gov (United States)

    Deng, Hua; Kennedy, Christopher W; Armour, Elwood; Tryggestad, Erik; Ford, Eric; McNutt, Todd; Jiang, Licai; Wong, John

    2007-05-21

    A small animal radiation platform equipped with on-board cone-beam CT and conformal irradiation capabilities is being constructed for translational research. To achieve highly localized dose delivery, an x-ray lens is used to focus the broad beam from a 225 kVp x-ray tube down to a beam with a full width half maximum (FWHM) of approximately 1.5 mm in the energy range 40-80 keV. Here, we report on the dosimetric characteristics of the focused beam from the x-ray lens subsystem for high-resolution dose delivery. Using the metric of the average dose within a 1.5 mm diameter area, the dose rates at a source-to-surface distance (SSD) of 34 cm are 259 and 172 cGy min(-1) at 6 mm and 2 cm depths, respectively, with an estimated uncertainty of +/-5%. The per cent depth dose is approximately 56% at 2 cm depth for a beam at 34 cm SSD.

  19. The small-animal radiation research platform (SARRP): dosimetry of a focused lens system

    International Nuclear Information System (INIS)

    Deng Hua; Kennedy, Christopher W; Armour, Elwood; Tryggestad, Erik; Ford, Eric; McNutt, Todd; Jiang Licai; Wong, John

    2007-01-01

    A small animal radiation platform equipped with on-board cone-beam CT and conformal irradiation capabilities is being constructed for translational research. To achieve highly localized dose delivery, an x-ray lens is used to focus the broad beam from a 225 kVp x-ray tube down to a beam with a full width half maximum (FWHM) of approximately 1.5 mm in the energy range 40-80 keV. Here, we report on the dosimetric characteristics of the focused beam from the x-ray lens subsystem for high-resolution dose delivery. Using the metric of the average dose within a 1.5 mm diameter area, the dose rates at a source-to-surface distance (SSD) of 34 cm are 259 and 172 cGy min -1 at 6 mm and 2 cm depths, respectively, with an estimated uncertainty of ±5%. The per cent depth dose is approximately 56% at 2 cm depth for a beam at 34 cm SSD

  20. Tanks Focus Area Alternative Salt Processing Research and Development Program Plan

    Energy Technology Data Exchange (ETDEWEB)

    Harmon, Harry D.

    2000-05-15

    In March 2000, DOE-Headquarters (HQ) requested the Tanks Focus Area (TFA)to assume management responsibility for the Salt Processing Project technology development program at Savannah River Site. The TFA was requested to conduct several activities, including review and revision of the technology development roadmaps, development of down-selection criteria, and preparation of a comprehensive Research and Development (R&D) Program Plan for three candidate cesium removal technologies, as well as the Alpha and strontium removal processes that must also be carried out. The three cesium removal candidate technologies are Crystalline Silicotitanate (CST) Non-Elutable Ion Exchange, Caustic Side Solvent Extraction (CSSX), and Small Tank Tetraphenylborate Precipitation (STTP). This plan describes the technology development needs for each process that must be satisfied in order to reach a down-selection decision, as well as continuing technology development required to support conceptual design activities.

  1. Tanks Focus Area Alternative Salt Processing Research and Development Program Plan

    Energy Technology Data Exchange (ETDEWEB)

    Harmon, Harry D.

    2000-11-30

    In March 2000, DOE-Headquarters (HQ) requested the Tanks Focus Area (TFA) to assume management responsibility for the Salt Processing Project technology development program at Savannah River Site. The TFA was requested to conduct several activities, including review and revision of the technology development roadmaps, development of down-selection criteria, and preparation of a comprehensive Research and Development (R&D) Program Plan for three candidate cesium removal technologies, as well as the Alpha and strontium removal processes that must also be carried out. The three cesium removal candidate technologies are Crystalline Silicotitanate (CST) Non-Elutable Ion Exchange, Caustic Side Solvent Extraction (CSSX), and Small Tank Tetraphenylborate Precipitation (STTP). This plan describes the technology development needs for each process that must be satisfied in order to reach a down-selection decision, as well as continuing technology development required to support conceptual design activities.

  2. Neuroeconomics: cross-currents in research on decision-making

    NARCIS (Netherlands)

    Sanfey, A.G.; Loewenstein, G.; McClure, S.M.; Cohen, J.D.

    2006-01-01

    Despite substantial advances, the question of how we make decisions and judgments continues to pose important challenges for scientific research. Historically, different disciplines have approached this problem using different techniques and assumptions, with few unifying efforts made. However, the

  3. Current state of seagrass ecosystem services: Research and policy integration

    KAUST Repository

    Ruiz-Frau, A.; Gelcich, S.; Hendriks, I.E.; Duarte, Carlos M.; Marbà , N.

    2017-01-01

    areas; a type of service research bias, provisioning and regulating services have received extensive attention while cultural services remain understudied; a type of discipline bias, the ecological aspects of SGES have been well documented while economic

  4. Italy. Report 2 [Marine Radioecology. Current Research and Future Scope

    Energy Technology Data Exchange (ETDEWEB)

    Schreiber, B. [Istituto di Zoologia, Universita-Parma (Italy)

    1967-03-15

    Present research programme (long-term): Radionuclides in plankton an marine sediments. Ecology of Anvantheria as Sr ''scanengers''. General distribution of radionuclides in marine environment Systematics and ecology of Avantharia, studied in different seas as a biological problem. Content of {sup 90}Sr in plankton in relation to the presence or absence of Avantharia Radiochemistry of sea sediments (littoral); sedimentological and petrographical researches for stratigraphic purposes. Fall-out and wastes radionuclides absorbed by sediments. Correlation between Acantharia and concentration factor for {sup 90}Sr. Stratigraphy of fall-out radionuclides in sea sediments. Biological researches on Acantharia rearing for turnover studies in vitro. Stratigraphical researches on recent coastal sediments for geochronological problems by means of fall-out radionuclides.

  5. Finland [Marine Radioecology. Current Research and Future Scope

    International Nuclear Information System (INIS)

    Miettinen, J. K.

    1967-01-01

    The research ideas given below are mainly based on experiences obtained in studies of radioecology in fresh waters but may be useful at least for comparison when considering radioecological studies in brackish and true ocean waters

  6. Italy. Report 2 [Marine Radioecology. Current Research and Future Scope

    International Nuclear Information System (INIS)

    Schreiber, B.

    1967-01-01

    Present research programme (long-term): Radionuclides in plankton an marine sediments. Ecology of Anvantheria as Sr ''scanengers''. General distribution of radionuclides in marine environment Systematics and ecology of Avantharia, studied in different seas as a biological problem. Content of 90 Sr in plankton in relation to the presence or absence of Avantharia Radiochemistry of sea sediments (littoral); sedimentological and petrographical researches for stratigraphic purposes. Fall-out and wastes radionuclides absorbed by sediments. Correlation between Acantharia and concentration factor for 90 Sr. Stratigraphy of fall-out radionuclides in sea sediments. Biological researches on Acantharia rearing for turnover studies in vitro. Stratigraphical researches on recent coastal sediments for geochronological problems by means of fall-out radionuclides

  7. Research on cancer diagnosis in Malaysia: current status.

    Science.gov (United States)

    Looi, L M; Zubaidah, Z; Cheah, P L; Cheong, S K; Gudum, H R; Iekhsan, O; Ikram, S I; Jamal, R; Mak, J W; Othman, N H; Puteri, J N; Rosline, H; Sabariah, A R; Seow, H F; Sharifah, N A

    2004-06-01

    Cancer is a major morbidity and mortality concern in Malaysia. Based on National Cancer Registry data, the Malaysian population is estimated to bear a cancer burden of about 40,000 new cases per year, and a cumulative lifetime risk of about 1:4. Cancer research in Malaysia has to consider needs relevant to our population, and resources constraints. Hence, funding bodies prioritise cancers of high prevalence, unique to our community and posing specific clinical problems. Cancer diagnosis is crucial to cancer management. While cancer diagnosis research largely aims at improvements in diagnostic information towards more appropriate therapy, it also impacts upon policy development and other areas of cancer management. The scope of cancer diagnosis upon which this paper is based, and their possible impact on other R&D areas, has been broadly categorized into: (1) identification of aetiological agents and their linkages to the development of precancer and cancer (impact on policy development, cancer prevention and treatment), (2) cancer biology and pathogenesis (impact on cancer prevention, treatment strategies and product development), (3) improvements in accuracy, sensitivity and specificity in cancer detection, monitoring and classification (impact on technology development) and (4) prognostic and predictive parameters (impact on treatment strategies). This paper is based on data collected by the Working Group on Cancer Diagnosis Research for the First National Conference on Cancer Research Coordination in April 2004. Data was collated from the databases of Institutions/Universities where the authors are employed, the Ministry of Science, Technology and Innovation (MOSTI) and targeted survey feedback from key cancer researchers. Under the 7th Malaysia Plan, 76 cancer projects were funded through the Intensified Research in Priority Areas (IRPA) scheme of MOSTI, amounting to almost RM15 million of grant money. 47(61.8%) of these projects were substantially in cancer

  8. Current status of quantitative rotational spectroscopy for atmospheric research

    Science.gov (United States)

    Drouin, Brian J.; Wlodarczak, Georges; Colmont, Jean-Marcel; Rohart, Francois

    2004-01-01

    Remote sensing of rotational transitions in the Earth's atmosphere has become an important method for the retrieval of geophysical temperatures, pressures and chemical composition profiles that requires accurate spectral information. This paper highlights the current status of rotational data that are useful for atmospheric measurements, with a discussion of the types the rotational lineshape measurements that are not generally available in either online repository.

  9. Current Research Activities of the Department of Oceanography.

    Science.gov (United States)

    1981-04-01

    support for teaching via blished comprehensive teaching and a large assortment of facilities and research programs, which are con- projects that are... teaching and re- Reichard, and Stephen Riser, joint search laboratories are augmented by appointments with JISAO, and Eric a research fleet consisting of...West. Botanica Marina 23: 333-341. No. 1124 Lewin, J., J.E. Eckman, and G.N. Ware (1979) Blooms of surf-zone diatoms along the coast of the Olympic

  10. Rice Genome Research: Current Status and Future Perspectives

    Directory of Open Access Journals (Sweden)

    Bin Han

    2008-11-01

    Full Text Available Rice ( L. is the leading genomics system among the crop plants. The sequence of the rice genome, the first cereal plant genome, was published in 2005. This review summarizes progress made in rice genome annotations, comparative genomics, and functional genomics researches. It also maps out the status of rice genomics globally and provides a vision of future research directions and resource building.

  11. Current research and development trends in floristic geography

    OpenAIRE

    Hang Sun; Tao Deng; Yongsheng Chen; Zhuo Zhou

    2017-01-01

    This paper summarizes the research status, existing issues, and trends in floristic geography. There is now a wealth of research accumulation on floristic investigations, distribution types of genera, floristic regions, and regional floristic analysis. It is also noted that most of these studies utilize simple statistical analyses, comparative studies, traditional methods, and single subjects, to provide a basic understanding and description of the floristic phenomenon, which is lacking spati...

  12. Worksite health promotion research: challenges, current state and future directions

    Directory of Open Access Journals (Sweden)

    Georg F. Bauer

    2007-12-01

    Full Text Available

    Background: Worksite health promotion (WHP addresses diverse individual and work-related health determinants. Thus, multiple, non-standardized interventions as well as company outcomes other than health have to be considered in WHP research.

    Methods: The article builds primarily on published research reviews in WHP and related fields. It discusses key practical and research challenges of the workplace setting. The evidence available on the effectiveness of WHP is summarised and conclusions are drawn for future WHP practice and research.

    Results: WHP research on health-oriented, behavioural interventions shows that the level of evidence ranges from suggestive to acceptable for key prevention areas such as physical activity, nutrition, fitness, smoking, alcohol and stress. Such interventions are effective if key conditions are met. Future research is needed on long-term effects, on multi-component programs and on programs, which address environmental determinants of health behaviour as well. Research on work-related determinants of health shows the economic and public health relevance of WHP interventions. Reviews of work-oriented, organisational interventions show that they produce a range of individual and organisational outcomes. However, due to the complexity of the organisational context, the generalisability and predictability of such outcomes remain limited.

    Conclusions: WHP research shows success factors of WHP and provides evidence of its effectiveness. In future, the evidence base should be expanded by developing adaptive, company-driven intervention approaches which allow for continuous optimisation of companies from a health perspective. Also, approaches for active dissemination of such a systemic-salutogenic occupational health management approach should be developed to increase the public health impact of WHP.

  13. Current research in transcultural psychiatry in the Nordic countries

    DEFF Research Database (Denmark)

    Ekblad, Solvig; Kastrup, Marianne Carisius

    2013-01-01

    This article discusses major themes in recent transcultural psychiatric research in the Nordic countries from 2008 to 2011: (a) epidemiological studies of migration, (b) indigenous populations, and (c) quality of psychiatric care for migrants. Over the past several decades, the populations......, and after migration, with potential effects on their physical, mental, social, and spiritual health. Growing interest in transcultural issues is reflected in the level of scientific research and clinical activity in the field by Nordic physicians, psychologists, social scientists, demographers, medical...

  14. Current issues in patient adherence and persistence: focus on anticoagulants for the treatment and prevention of thromboembolism

    Directory of Open Access Journals (Sweden)

    Patrick P Kneeland

    2010-03-01

    Full Text Available Patrick P Kneeland, Margaret C FangThe University of California, San Francisco Division of Hospital Medicine, San Francisco, CA, USAAbstract: Warfarin therapy reduces morbidity and mortality related to thromboembolism. Yet adherence to long-term warfarin therapy remains challenging due to the risks of anticoagulantassociated complications and the burden of monitoring. The aim of this paper is to review determinants of adherence and persistence on long-term anticoagulant therapy for atrial fibrillation and venous thromboembolism. We evaluate what the current literature reveals about the impact of warfarin on quality of life, examine warfarin trial data for patterns of adherence, and summarize known risk factors for warfarin discontinuation. Studies suggest only modest adverse effects of warfarin on quality of life, but highlight the variability of individual lifestyle experiences of patients on warfarin. Interestingly, clinical trials comparing anticoagulant adherence to alternatives (such as aspirin show that discontinuation rates on warfarin are not consistently higher than in control arms. Observational studies link a number of risk factors to warfarin non-adherence including younger age, male sex, lower stroke risk, poor cognitive function, poverty, and higher educational attainment. In addition to differentiating the relative impact of warfarin-associated complications (such as bleeding versus the lifestyle burdens of warfarin monitoring on adherence, future investigation should focus on optimizing patient education and enhancing models of physician–patient shared-decision making around anticoagulation.Keywords: anticoagulation, warfarin, adherence, persistence, thromboembolism

  15. A study on the continuing education of radiologic technologists: Focused on current status and satisfaction of continuing education

    International Nuclear Information System (INIS)

    Min, Hye Lim; Choi, In Seok; Nam, So Ra; Kim, Hyun Ji; Yoon, Yong Su; Her, Jae; Han, Seong Gyu; Kim, Jung Min; Ahn, Duck Sun

    2014-01-01

    In this study, we surveyed the current status, satisfaction and demand of radiologic technologist continuing education for 93 radiologic technologists who participated in the continuing education. To understand the current status and general evaluation and to find out the improvement direction, survey was conducted on 3 categories: participation, satisfaction and demand of continuing education. In addition, we analyzed the continuing education implementation status and the management system by collecting related regulations. As a result, the education completion rates of radiologic technologists from 2010 to 2012 were respectively 42.6%, 43.4% and 34.2%; the rates were similar to other medical technician’s average education completion rates. According to the survey, in case of participation, the most frequent answer was ‘more than five times less than 10 times per year’ with 48.4% and in satisfaction section, the most common answer was ‘Average(3)’ with 34.4%. In demand of continuing education section, 32.8% of the respondents chose ‘Clinical skill training in major field’. In the results of this research, continuing education needs to be managed in the direction of helping radiologists improve their personal ability and self development. Furthermore, to meet the demand of radiologists, the quality of continuing education should be improved to satisfy the educatee

  16. Researches on regenerative medicine-current state and prospect.

    Science.gov (United States)

    Wang, Zheng-Guo; Xiao, Kai

    2012-01-01

    Since 1980s, the rapid development of tissue engineering and stem cell research has pushed regenerative medicine to a new fastigium, and regenerative medicine has become a noticeable research field in the international biology and medicine. In China, about 100 million patients need repair and regeneration treatment every year, while the number is much larger in the world. Regenerative medicine could provide effective salvation for these patients. Both Chinese Academy of Sciences and Chinese Academy of Engineering have made roadmaps of 2010-2050 and 2011-2030 for regenerative medicine. The final goal of the two roadmaps is to make China go up to leading position in most research aspects of regenerative medicine. In accord with this strategy, the government and some enterprises have invested 3-5 billion RMB (0.5-0.8 billion USD) for the research on regenerative medicine. In order to push the translation of regenerative medicine forward-from bench to bedside, a strategic alliance has been established, and it includes 27 top-level research institutes, medical institutes, colleges, universities and enterprises in the field of stem cell and regeneration medicine. Recently the journal, Science, has published a special issue-Regenerative Medicine in China, consisting of 35 papers dealing with stem cell and regeneration, tissue engineering and regeneration, trauma and regeneration and bases for tissue repair and regenerative medicine. It is predicated that a greater breakthrough in theory and practice of regenerative medicine will be achieved in the near future (20 to 30 years).

  17. Review of current status of LWR safety research in Japan

    International Nuclear Information System (INIS)

    Yamada, Tasaburo; Mishima, Yoshitsugu; Ando, Yoshio; Miyazono, Shohachiro; Takashima, Yoichi.

    1977-01-01

    The Japan Atomic Energy Commission has exerted efforts on the research of the safety of nuclear plants in Japan, and ''Nuclear plant safety research committees'' was established in August 1974, which is composed of the government and the people. The philosophy of safety research, research and development plan, the forwarding procedure of the plan, international cooperation, for example LOFT program, and the effective feed back of the experimental results concerning nuclear safety are reviewed in this paper at first. As for the safety of nuclear reactors the basic philosophy that radio active fission products are contained in fuel or reactors with multiple barriers, (defence in depth) and almost no fission product is released outside reactor plants even at the time of hypothetical accident, is kept, and the research and development history and the future plan are described in this paper with the related technical problems. The structural safety is also explained, for example, on the philosophy ''leak before break'', pipe rupture, pipe restraint and stress analysis. The release of radioactive gas and liquid is decreased as the philosophy ''ALAP''. And probability safety evaluation method, LOCA, reactivity, accident and aseismatic design in nuclear plants in Japan are described. (Nakai, Y.)

  18. Nuclear Waste Separation and Transmutation Research with Special Focus on Russian Transmutation Projects Sponsored by ISTC

    International Nuclear Information System (INIS)

    Conde, Henri; Blomgren, Jan; Olsson, Nils

    2003-03-01

    High-level nuclear reactor waste is made up of relatively few long-lived radioactive species, among them plutonium, that contribute to difficulties with its storage and disposal. Separation of these species from larger waste volumes mainly constituting of uranium (about 95 %) coupled with nuclear incineration to fission products of plutonium and the so called minor actinides (Neptunium, Americium, and Curium) and transmutation of some of the long lived fission products to short lived or stable isotopes represents a viable nuclear waste management strategy to drastically reduce the time and space requirements for a bed-rock repository of the remaining waste. A remarkable increase in the international research and development on partitioning and transmutation has occurred during the recent years. The road-map report published in April 2001 by The European Technical Working Group on ADS for the development of a European demonstration facility for nuclear waste transmutation has high-lighted the ongoing European research and pointed out the need for further research. The road-map has given the different research activities a position in the ultimate goal of producing an ADS demonstrator and is guiding research planning on the national as well as on the EU level. The Advanced Accelerator Application (3A) program in the US, with the long term goals to enhance long term public safety, provide benefits for the repository, reduce proliferation risks and improve prospects for nuclear power has focused the research on nuclear waste transmutation. The reports on the 3A program indicates a change of the US former abandonment position towards reprocessing and fast reactors due to a strong incentive to eliminate the reactor plutonium and to lower the amount of high level reactor waste for the Yucca Mountain repository. The SKB's proposed research and development program for the next 3 years (FUD01) was presented by SKB in September 2001. It is proposed that the research program

  19. A Study of Factors Related to Dissertation Progress among Doctoral Candidates: Focus on Students' Research Self-Efficacy as a Result of Their Research Training and Experiences.

    Science.gov (United States)

    Faghihi, Forooz; Rakow, Ernest A.; Ethington, Corinna

    This study examined relationships among doctoral candidates' background characteristics, research preparation, research environment, research involvement, student-advisor relationship, research self-efficacy, and dissertation progress. The study focused on differences in research self-efficacy and dissertation progress among students from the…

  20. Third-generation biofuels: current and future research on microalgal lipid biotechnology

    Directory of Open Access Journals (Sweden)

    Li-Beisson Yonghua

    2013-11-01

    Full Text Available One pressing issue faced by modern societies is to develop renewable energy for transportation. Microalgal biomass offers an attractive solution due to its high (annual surface biomass productivity, efficient conversion of solar energy into chemical energy and the ability to grow on non-agricultural land. Despite these considerable advantages, microalgal biofuels are not yet commercially sustainable. Major challenges lie in improving both cultivation technologies and microalgal strains. A microalgal crop species is yet to emerge. In this review, we focus on researches aiming at understanding and harnessing lipid metabolism in microalgae in view of producing lipid-based biofuels such as biodiesel. Current biotechnological challenges and key progresses made in the development of algal models, genetic tools and lipid metabolic engineering strategies are reviewed. Possible future research directions to increase oil yields in microalgae are also highlighted.

  1. Significance of Pharmacogenetics and Pharmacogenomics Research in Current Medical Practice.

    Science.gov (United States)

    Prakash, Swayam; Agrawal, Suraksha

    2016-01-01

    Human genome sequencing highlights the involvement of genetic variation towards differential risk of human diseases, presence of different phenotypes, and response to pharmacological elements. This brings the field of personalized medicine to forefront in the era of modern health care. Numerous recent approaches have shown that how variation in the genome at single nucleotide level can be used in pharmacological research. The two broad aspects that deal with pharmacological research are pharmacogenetics and pharmacogenomics. This review encompasses how these variations have created the basis of pharmacogenetics and pharmacogenomics research and important milestones accomplished in these two fields in different diseases. It further discusses at length their importance in disease diagnosis, response of drugs, and various treatment modalities on the basis of genetic determinants.

  2. Transcranial Direct Current Stimulation: Considerations for Research in Adolescent Depression

    Directory of Open Access Journals (Sweden)

    Jonathan C. Lee

    2017-06-01

    Full Text Available Adolescent depression is a prevalent disorder with substantial morbidity and mortality. Current treatment interventions do not target relevant pathophysiology and are frequently ineffective, thereby leading to a substantial burden for individuals, families, and society. During adolescence, the prefrontal cortex undergoes extensive structural and functional changes. Recent work suggests that frontolimbic development in depressed adolescents is delayed or aberrant. The judicious application of non-invasive brain stimulation techniques to the prefrontal cortex may present a promising opportunity for durable interventions in adolescent depression. Transcranial direct current stimulation (tDCS applies a low-intensity, continuous current that alters cortical excitability. While this modality does not elicit action potentials, it is thought to manipulate neuronal activity and neuroplasticity. Specifically, tDCS may modulate N-methyl-d-aspartate receptors and L-type voltage-gated calcium channels and effect changes through long-term potentiation or long-term depression-like mechanisms. This mini-review considers the neurobiological rationale for developing tDCS protocols in adolescent depression, reviews existing work in adult mood disorders, surveys the existing tDCS literature in adolescent populations, reviews safety studies, and discusses distinct ethical considerations in work with adolescents.

  3. [Advances in research on cognitive function related to temporal lobe epilepsy: focus on social cognitive function].

    Science.gov (United States)

    Yamano, Mitsuhiko; Akamatsu, Naoki; Tsuji, Sadatoshi

    2012-09-01

    Research on cognitive function related to temporal lobe epilepsy has thus far focused on memory, language, and general intelligence. Recently, however, the concept of social cognitive function has been proposed in the field of neuropsychology. Social cognitive function refers collectively to the higher cognitive functions that are essential in our social lives, and its representative aspects are facial expression recognition and decision-making. Emotional processing centered around the amygdala is thought to play a key role in the neural mechanism of this function. We conducted a study on the social cognitive function (decision-making) of patients with temporal lobe epilepsy, and found that this function is reduced in these patients, and that the right amygdalo-hippocampal complexes play an important role. In order to ensure the best possible treatment for epilepsy patients, it is necessary not only to make an accurate diagnosis and provide appropriate treatment, but also to provide support for enabling a smoother social life from the perspective of social cognitive function. Future research developments in this field are expected to contribute to total management in medical care for epilepsy patients.

  4. Advances in Proteomic Techniques for Cytokine Analysis: Focus on Melanoma Research

    Directory of Open Access Journals (Sweden)

    Helena Kupcova Skalnikova

    2017-12-01

    Full Text Available Melanoma is a skin cancer with permanently increasing incidence and resistance to therapies in advanced stages. Reports of spontaneous regression and tumour infiltration with T-lymphocytes makes melanoma candidate for immunotherapies. Cytokines are key factors regulating immune response and intercellular communication in tumour microenvironment. Cytokines may be used in therapy of melanoma to modulate immune response. Cytokines also possess diagnostic and prognostic potential and cytokine production may reflect effects of immunotherapies. The purpose of this review is to give an overview of recent advances in proteomic techniques for the detection and quantification of cytokines in melanoma research. Approaches covered span from mass spectrometry to immunoassays for single molecule detection (ELISA, western blot, multiplex assays (chemiluminescent, bead-based (Luminex and planar antibody arrays, ultrasensitive techniques (Singulex, Simoa, immuno-PCR, proximity ligation/extension assay, immunomagnetic reduction assay, to analyses of single cells producing cytokines (ELISpot, flow cytometry, mass cytometry and emerging techniques for single cell secretomics. Although this review is focused mainly on cancer and particularly melanoma, the discussed techniques are in general applicable to broad research field of biology and medicine, including stem cells, development, aging, immunology and intercellular communication.

  5. India [Marine Radioecology. Current Research and Future Scope

    International Nuclear Information System (INIS)

    Ganguly, A.K.; Viswanathan, R.; Patel, B.; Bhatt, Y.M.; Pillai, K.C.

    1967-01-01

    Present research programme (long-term) - Radioactivity studies in the marine environment of the West Coast of India: (a) To understand the radioactivity and trace-element distribution in the continental shelf in Arabian Sea. This has the twin objectives of gaining basic information on marine geochemistry and marine biochemistry and assessing the capacity of the region to receive radioactive wastes from atomic energy installations. (b) To derive maximum permissible radioactive contamination limits in sea-water, marine organisms and marine products. (c) To collaborate with IAEA in research contract (Project Marina) with objectives stated in (a) and (b) above

  6. Current research on parenting styles, dimensions, and beliefs.

    Science.gov (United States)

    Smetana, Judith G

    2017-06-01

    For decades, parenting has been characterized in terms of broad global styles, with authoritative parenting seen as most beneficial for children's development. Concerns with greater sensitivity to cultural and contextual variations have led to greater specificity in defining parenting in terms of different parenting dimensions and greater consideration of the role of parenting beliefs in moderating links between parenting and adjustment. New research includes 'domain-specific' models that describe parents as flexibly deploying different practices depending on their goals, children's needs, and the types of behaviors towards which parenting is directed. These trends are described, and directions for future research are discussed. Copyright © 2017 Elsevier Ltd. All rights reserved.

  7. Current tendencies and perspectives of development research reactors of Russia

    International Nuclear Information System (INIS)

    Gabaraev, B.A.; Kchmelschikov, V.V.

    2004-01-01

    Full text: During more than fifty years many Research Reactors were constructed under Russian projects, and that is a considerable contribution to the world reactor building. The designs of Research Reactors, constructed under Russian projects, appeared to be so successful, that permitted to raise capacity and widen the range of their application. The majority of Russian Research Reactors being middle-aged are far from having their designed resources exhausted and are kept on the intensive run still. In 2000 'Strategy of nuclear power development in Russia in the first half of XXI century' was elaborated and approved. The national nuclear power requirements and possible ways of its development determined in this document demanded to analyze the state of the research reactors base. The analysis results are presented in this report. The main conclusion consists in the following statement: on the one hand quantity and experimental potentialities of domestic Research Reactors are sufficient for the solution of reactor materials science tasks, and on the other hand the reconstruction and modernization appears to be the most preferable way of research reactors development for the near-term outlook. At present time the modernization and reconstruction works and works on extension of operational life of high-powered multipurpose MIR-M1, SM-3, IRV-1M, BOR-60, IVV-2M and others are conducted. There is support for the development of Research Reactors, intended for carrying out the fundamental investigations on the neutron beams. Toward this end the Government of Russia gives financial and professional support with a view to complete the reactor PIK construction in PINPh and the reactor IBR-2 modernization in JINR. In future prospect Research Reactors branch in Russia is to acquire the following trends: - limited number of existent scientific centers, based on the construction sites, with high flux materials testing research reactors, equipped with experimental facilities

  8. Current research in Spain on walnut for wood production

    Science.gov (United States)

    Neus Alet& #224; Neus NO-VALUE

    2004-01-01

    The Department of Mediterranean Trees at the Institut de Recerca i Tecnologia Agroalimentaries (IRTA) in Spain initiated a research program in 1993 to examine the variability among walnut species for wood production and to establish orchards with improved selections. The main objective of the programme is to obtain superior Persian walnut (Juglans regia...

  9. Yugoslavia. Report 2 [Marine Radioecology. Current Research and Future Scope

    International Nuclear Information System (INIS)

    Branica, M.

    1967-01-01

    Present research programme (long-term): Physico-chemical investigations of micro-constituents in sea water. Determination of redox ionic state, complexibility, quantities and precipitation of micro-constituents in sea water. The physico-chemical state and quantity of micro-constituents is very important for the elucidation of the mechanism of transport and fixation of radionuclides into sediments and the biota

  10. EPA Current Research on Cyanotoxins in Fish Tissue

    Science.gov (United States)

    This is a presentation regarding research into the recovery of microcystins from fish tissue. The potential bioaccumulation of toxins is of potential health both because of the direct risk of consumption and the potential for bioaccumulation of toxins. This is a short presentatio...

  11. Current state of seagrass ecosystem services: Research and policy integration

    KAUST Repository

    Ruiz-Frau, A.

    2017-10-12

    Seagrasses contribute to the maintenance of human wellbeing. However certain aspects of their role as ecosystem service (ES) providers remain understudied. Here, we synthesise the state of seagrass ES (SGES) research and policy implications. Additionally, we recommend ways in which SGES research can be integrated in to policy design, by drawing lessons from the case of Blue Carbon (BC). SGES research suffers from three main biases: a geographical bias, SGES has been restricted to chartered seagrass areas; a type of service research bias, provisioning and regulating services have received extensive attention while cultural services remain understudied; a type of discipline bias, the ecological aspects of SGES have been well documented while economic and social aspects remain in comparison understudied. These are particularly important, as an understanding of the social and economic considerations of the provision of ES is fundamental to facilitate its integration into policy frameworks. Lessons drawn from the operationalization process of BC show the reoccurrence of certain aspects that have enabled the integration of BC into policy. These aspects are grouped under 4 different categories. From the analysis of these elements we draw lessons that could facilitate the operationalization of other ecosystem services and their incorporation into management policy frameworks.

  12. Yugoslavia. Report 2 [Marine Radioecology. Current Research and Future Scope

    Energy Technology Data Exchange (ETDEWEB)

    Branica, M. [Laboratory for Physico-Chemical Separations, Institute ' ' Ruder Boskovic' ' , Zagreb, Yugoslavia (Croatia)

    1967-03-15

    Present research programme (long-term): Physico-chemical investigations of micro-constituents in sea water. Determination of redox ionic state, complexibility, quantities and precipitation of micro-constituents in sea water. The physico-chemical state and quantity of micro-constituents is very important for the elucidation of the mechanism of transport and fixation of radionuclides into sediments and the biota.

  13. Yugoslavia. Report 1 [Marine Radioecology. Current Research and Future Scope

    Energy Technology Data Exchange (ETDEWEB)

    Kečkeš, S.; Pučar, Z. [Laboratory of Marine Radiobiology and Laboratory for Electromigration, Institute ' ' Ruder Boskovic' ' , Rovinj and Zagreb, Yugoslavia (Croatia)

    1967-03-15

    Present research programme (long-term): Transport of various radiqnuclides in marine environment. Uptake, loss and accumulation of radionuclides in selected marine biota. Study of the physico-chemical forms of various radionuclides in sea water. Tracer experiments on the uptake and loss rate in biota. Electromigration techniques for the characterization of the physico-chemical forms of radionuclides.

  14. Gifted Male Readers: Current Understandings and Suggestions for Future Research

    Science.gov (United States)

    Pagnani, Alexander R.

    2013-01-01

    Research literature concerning gifted male readers relies primarily on more extensive bodies of work regarding gifted males and male readers. Studied as a whole, the two halves portray a worrisome state of affairs for gifted male readers, who lag behind their female counterparts in the same patterns found across the ability spectrum. This literacy…

  15. Mathematicians' Views on Current Publishing Issues: A Survey of Researchers

    Science.gov (United States)

    Fowler, Kristine K.

    2011-01-01

    This article reports research mathematicians' attitudes about and activity in specific scholarly communication areas, as captured in a 2010 survey of more than 600 randomly-selected mathematicians worldwide. Key findings include: (1) Most mathematicians have papers in the arXiv, but posting to their own web pages remains more common; (2) A third…

  16. Current research in transcultural psychiatry in the Nordic countries.

    Science.gov (United States)

    Ekblad, Solvig; Kastrup, Marianne Carisius

    2013-12-01

    This article discusses major themes in recent transcultural psychiatric research in the Nordic countries from 2008 to 2011: (a) epidemiological studies of migration, (b) indigenous populations, and (c) quality of psychiatric care for migrants. Over the past several decades, the populations of the Nordic countries, Denmark, Finland, Norway, and Sweden, which were relatively homogeneous, have become increasingly culturally diverse. Many migrants to Nordic countries have been exposed to extreme stress, such as threats of death and/or torture and other severe social adversities before, during, and after migration, with potential effects on their physical, mental, social, and spiritual health. Growing interest in transcultural issues is reflected in the level of scientific research and clinical activity in the field by Nordic physicians, psychologists, social scientists, demographers, medical anthropologists, as well as other clinicians and policy planners. Research includes work with migrants and indigenous minorities in the Nordic countries, as well as comparisons with mental health in postconflict countries. We conclude by suggesting future directions for transcultural psychiatry research and providing guidelines for the education and training of future clinicians in the Nordic countries.

  17. The Contribution of Current Research and Development Projects

    Science.gov (United States)

    Townsend, H. E. R.

    1973-01-01

    Reviews recent projects on the education of immigrants within the framework of the six suggestions for research made by the Select Committee on Race Relations and Immigrations; e.g. the effects on children of various educational arrangements for immigrants; methods of teaching race relations in schools; and others. (Author/JM)

  18. Talent management : Current theories and future research directions

    NARCIS (Netherlands)

    Al Ariss, A.; Cascio, W.F.; Paauwe, J.

    2014-01-01

    Research on Talent Management (TM) has been lagging behind businesses in offering vision and leadership in this field. After sketching a comprehensive outline of knowledge about TM, theoretical as well as practical, we introduce the papers in this special issue and their important contributions.

  19. Current application of chemometrics in traditional Chinese herbal medicine research.

    Science.gov (United States)

    Huang, Yipeng; Wu, Zhenwei; Su, Rihui; Ruan, Guihua; Du, Fuyou; Li, Gongke

    2016-07-15

    Traditional Chinese herbal medicines (TCHMs) are promising approach for the treatment of various diseases which have attracted increasing attention all over the world. Chemometrics in quality control of TCHMs are great useful tools that harnessing mathematics, statistics and other methods to acquire information maximally from the data obtained from various analytical approaches. This feature article focuses on the recent studies which evaluating the pharmacological efficacy and quality of TCHMs by determining, identifying and discriminating the bioactive or marker components in different samples with the help of chemometric techniques. In this work, the application of chemometric techniques in the classification of TCHMs based on their efficacy and usage was introduced. The recent advances of chemometrics applied in the chemical analysis of TCHMs were reviewed in detail. Copyright © 2015 Elsevier B.V. All rights reserved.

  20. Engaging families in physical activity research: a family-based focus group study.

    Science.gov (United States)

    Brown, Helen Elizabeth; Schiff, Annie; van Sluijs, Esther M F

    2015-11-25

    Family-based interventions present a much-needed opportunity to increase children's physical activity levels. However, little is known about how best to engage parents and their children in physical activity research. This study aimed to engage with the whole family to understand how best to recruit for, and retain participation in, physical activity research. Families (including a 'target' child aged between 8 and 11 years, their parents, siblings, and others) were recruited through schools and community groups. Focus groups were conducted using a semi-structured approach (informed by a pilot session). Families were asked to order cards listing the possible benefits of, and the barriers to, being involved in physical activity research and other health promotion activities, highlighting the items they consider most relevant, and suggesting additional items. Duplicate content analysis was used to identify transcript themes and develop a coding frame. Eighty-two participants from 17 families participated, including 17 'target' children (mean age 9.3 ± 1.1 years, 61.1% female), 32 other children and 33 adults (including parents, grandparents, and older siblings). Social, health and educational benefits were cited as being key incentives for involvement in physical activity research, with emphasis on children experiencing new things, developing character, and increasing social contact (particularly for shy children). Children's enjoyment was also given priority. The provision of child care or financial reward was not considered sufficiently appealing. Increased time commitment or scheduling difficulties were quoted as the most pertinent barriers to involvement (especially for families with several children), but parents commented these could be overcome if the potential value for children was clear. Lessons learned from this work may contribute to the development of effective recruitment and retention strategies for children and their families. Making the wide

  1. Nanomaterials in Lubricants: An Industrial Perspective on Current Research

    Directory of Open Access Journals (Sweden)

    Boris Zhmud

    2013-11-01

    Full Text Available This paper presents an overview on the use of various classes of nanomaterials in lubricant formulations. The following classes of nanomaterials are considered: fullerenes, nanodiamonds, ultradispersed boric acid and polytetrafluoroethylene (PTFE. Current advances in using nanomaterials in engine oils, industrial lubricants and greases are discussed. Results of numerous studies combined with formulation experience of the authors strongly suggest that nanomaterials do indeed have potential for enhancing certain lubricant properties, yet there is a long way to go before balanced formulations are developed.

  2. Icing Branch Current Research Activities in Icing Physics

    Science.gov (United States)

    Vargas, Mario

    2009-01-01

    Current development: A grid block transformation scheme which allows the input of grids in arbitrary reference frames, the use of mirror planes, and grids with relative velocities has been developed. A simple ice crystal and sand particle bouncing scheme has been included. Added an SLD splashing model based on that developed by William Wright for the LEWICE 3.2.2 software. A new area based collection efficiency algorithm will be incorporated which calculates trajectories from inflow block boundaries to outflow block boundaries. This method will be used for calculating and passing collection efficiency data between blade rows for turbo-machinery calculations.

  3. The need for a behavioural science focus in research on mental health and mental disorders

    DEFF Research Database (Denmark)

    Wittchen, Hans-Ulrich; Knappe, Susanne; Andersson, Gerhard

    2014-01-01

    of patients who already have developed a disease to improve medical treatment, the proposed framework model, linked to a concerted funding programme of the "Science of Behaviour Change", carries the promise of improved diagnosis, treatment and prevention of health-risk behaviour constellations as well......Psychology as a science offers an enormous diversity of theories, principles, and methodological approaches to understand mental health, abnormal functions and behaviours and mental disorders. A selected overview of the scope, current topics as well as strength and gaps in Psychological Science may...... help to depict the advances needed to inform future research agendas specifically on mental health and mental disorders. From an integrative psychological perspective, most maladaptive health behaviours and mental disorders can be conceptualized as the result of developmental dysfunctions...

  4. CYBERQUEER – MAJOR TOPICS AND ISSUES IN CURRENT RESEARCH

    Directory of Open Access Journals (Sweden)

    SIMONA RODAT

    2014-12-01

    Full Text Available The emergence of the opportunities opened by the internet raises also questions of interest for research regarding the extent to which these have an impact on the formations of non heterosexual life and on the experience of marginalised sexual identities. There have been different approaches in this regard and answers vary from optimistic and utopian appraisals concerning cyberspace in the early 90s to the more moderate and sceptic visions in the 2000s. Starting from this framework of debates, the present paper aims to explore the meaning of the term “cyberqueer”, including the theoretical context of its occurrence, to briefly highlight some critical considerations relating to cyberqueer research and to look over the main recurrent themes linked up with this concept, such as queer and cyberqueer identity, body and (disembodied practices and the forthcoming process of blurring the dividing boundaries between real/virtual, online/offline and public/private

  5. Neuroeconomics: cross-currents in research on decision-making.

    Science.gov (United States)

    Sanfey, Alan G; Loewenstein, George; McClure, Samuel M; Cohen, Jonathan D

    2006-03-01

    Despite substantial advances, the question of how we make decisions and judgments continues to pose important challenges for scientific research. Historically, different disciplines have approached this problem using different techniques and assumptions, with few unifying efforts made. However, the field of neuroeconomics has recently emerged as an inter-disciplinary effort to bridge this gap. Research in neuroscience and psychology has begun to investigate neural bases of decision predictability and value, central parameters in the economic theory of expected utility. Economics, in turn, is being increasingly influenced by a multiple-systems approach to decision-making, a perspective strongly rooted in psychology and neuroscience. The integration of these disparate theoretical approaches and methodologies offers exciting potential for the construction of more accurate models of decision-making.

  6. Incredible Years parenting interventions: current effectiveness research and future directions.

    Science.gov (United States)

    Gardner, Frances; Leijten, Patty

    2017-06-01

    The Incredible Years parenting intervention is a social learning theory-based programme for reducing children's conduct problems. Dozens of randomized trials, many by independent investigators, find consistent effects of Incredible Years on children's conduct problems across multiple countries and settings. However, in common with other interventions, these average effects hide much variability in the responses of individual children and families. Innovative moderator research is needed to enhance scientific understanding of why individual children and parents respond differently to intervention. Additionally, research is needed to test whether there are ways to make Incredible Years more effective and accessible for families and service providers, especially in low resource settings, by developing innovative delivery systems using new media, and by systematically testing for essential components of parenting interventions. Copyright © 2017. Published by Elsevier Ltd.

  7. Current Knowledge and Recent Advances in Marine Dinoflagellate Transcriptomic Research

    Directory of Open Access Journals (Sweden)

    Muhamad Afiq Akbar

    2018-02-01

    Full Text Available Dinoflagellates are essential components in marine ecosystems, and they possess two dissimilar flagella to facilitate movement. Dinoflagellates are major components of marine food webs and of extreme importance in balancing the ecosystem energy flux in oceans. They have been reported to be the primary cause of harmful algae bloom (HABs events around the world, causing seafood poisoning and therefore having a direct impact on human health. Interestingly, dinoflagellates in the genus Symbiodinium are major components of coral reef foundations. Knowledge regarding their genes and genome organization is currently limited due to their large genome size and other genetic and cytological characteristics that hinder whole genome sequencing of dinoflagellates. Transcriptomic approaches and genetic analyses have been employed to unravel the physiological and metabolic characteristics of dinoflagellates and their complexity. In this review, we summarize the current knowledge and findings from transcriptomic studies to understand the cell growth, effects on environmental stress, toxin biosynthesis, dynamic of HABs, phylogeny and endosymbiosis of dinoflagellates. With the advancement of high throughput sequencing technologies and lower cost of sequencing, transcriptomic approaches will likely deepen our understanding in other aspects of dinoflagellates’ molecular biology such as gene functional analysis, systems biology and development of model organisms.

  8. Current Status and Research into Overcoming Limitations of Capsule Endoscopy

    Directory of Open Access Journals (Sweden)

    Won Gun Kwack

    2016-01-01

    Full Text Available Endoscopic investigation has a critical role in the diagnosis and treatment of gastrointestinal (GI diseases. Since 2001, capsule endoscopy (CE has been available for small-bowel exploration and is under continuous development. During the past decade, CE has achieved impressive improvements in areas such as miniaturization, resolution, and battery life. As a result, CE is currently a first-line tool for the investigation of the small bowel in obscure gastrointestinal bleeding and is a useful alternative to wired enteroscopy. Nevertheless, CE still has several limitations, such as incomplete examination and limited diagnostic and therapeutic capabilities. To resolve these problems, many groups have suggested several models (e.g., controlled CO2 insufflation system, magnetic navigation system, mobile robotic platform, tagging and biopsy equipment, and targeted drug-delivery system, which are in development. In the near future, new technological advances will improve the capabilities of CE and broaden its spectrum of applications not only for the small bowel but also for the colon, stomach, and esophagus. The purpose of this review is to introduce the current status of CE and to review the ongoing development of solutions to address its limitations.

  9. Magnetic spectrograph with a semicircular focusing for studies on the energy distribution of a high-current relativistic electron beam

    International Nuclear Information System (INIS)

    Gosteva, T.S.; Zablotskaya, G.R.; Ivanov, B.A.; Kolyubakin, S.A.; Chernobrovin, V.I.

    1975-01-01

    Specific features of a magnetic spectrograph with a semicircular focusing are described; the spectrograph has been designed to study, using the REP-5 pulsed accelerator, the energy spectra of electrons with a current of 50 kA, pulse duration of 20 ns in the energy range 0.2 to 3 MeV. The beam has been transported in a drift chamber where the air pressure varies from 10 -3 to 40 torr. The chamber is 50 cm long and 12 cm in diameter. The spectrograph vacuum chamber is made in the form of a plane rectangular box with a degassing fitting. The uniform magnetic field in the spectrograph gap is provided with permanent magnets (ferrite-barium plates). The collimator and the chamber walls on which the magnets are located, are made of low-carbon electrotechnical steel. The diameters of the collimator entrance and exit windows are 2 and 0.2 mm, respectively. To screen the photofilm in the spectrograph chamber from x-radiation, there are three disks on the spectrograph flange on the part of the drift chamber, they are made of lead, steel, and aluminium. The steel disk, besides, screens the space in front of the collimator entrance window from the scattered magnetic field. During the experiments the pressure in the spectrograph chamber has varied from 7x10 -3 to 10 -1 torr. Electrons are registered using the RT-1 and RT-5 x-ray films 1x18 cm in size. The spectrograph described makes it possible to have well-resolved electron spectrum during a pulse. The electron spectra obtained by means of the spectrograph at a pressure of 4.10 -1 torr in the drift chamber and a charge voltage of 3.2 MV in the line, are shown [ru

  10. Current status of sodium fire and aerosol research in Japan

    International Nuclear Information System (INIS)

    Himeno, Yoshiaki

    1989-01-01

    State-of-the-art of the research and development related to sodium fire and aerosol behaviour is presented. This paper covers the Japanese work on sodium leak, leak detector, sodium oxidation and combustion, sodium aerosol release, fire mitigation, reliabilities of the electrical instruments and the reactor components under the sodium aerosols suspended atmosphere, aerosol plugging in a leak path, and the computer codes are presented. (author)

  11. Current results of coal gasification materials research at GRI

    International Nuclear Information System (INIS)

    Hill, V.L.; Barone, S.P.; Meyer, H.S.

    1984-01-01

    Corrosion, erosion/corrosion and mechanical property testing of commercial available materials in coal gasification atmospheres has been supported by the Gas Research Institute (GRI) since 1978. Recent corrosion data developed in the program for gasification and methanation technologies under development by GRI are presented. A brief discussion of typical results of long-term stress-rupture tests in coal gasification atmospheres is included

  12. Where Is Current Research on Blockchain Technology? - A Systematic Review

    OpenAIRE

    Yli-Huumo, Jesse; Ko, Deokoon; Choi, Sujin; Park, Sooyong; Smolander, Kari

    2016-01-01

    Blockchain is a decentralized transaction and data management technology developed first for Bitcoin cryptocurrency. The interest in Blockchain technology has been increasing since the idea was coined in 2008. The reason for the interest in Blockchain is its central attributes that provide security, anonymity and data integrity without any third party organization in control of the transactions, and therefore it creates interesting research areas, especially from the perspective of technical ...

  13. Current status of international cooperation on nuclear safety research

    International Nuclear Information System (INIS)

    Katsuragi, Satoru

    1984-01-01

    JAERI (Japan Atomic Energy Research Institute), as a representative organization in Japan, has been participating in many international cooperations on nuclear safety research. This report reviews the recent achievement and evolution of the international cooperative safety studies. Twelve projects that are based on the agreements between JAERI and foreign organizations are reviewed. As the fuel irradiation studies, the recent achievement of the OECD Halden Reactor Project and the agreement between Pacific Northwest Laboratories, Battelle Memorial Institute, and JAERI are explained. As for the study of reactivity accident, the cooperation of the NSRR (Nuclear Safety Research Reactor) project in Japan with PBF, PNS and PHEBUS projects in the U.S., West Germany and France, respectively, are now in progress. The fuel performance in abnormal transient and the experiment and analysis of severe fuel damage are the new areas of international interest. The OECD/LOFT project and ROSA-4 projects are also explained in connection with the FP source term problem and the analysis codes such as RELAP-5 and TRAC. As the safety studies associated with the downstream of the nuclear fuel cycle, the BEFAST project of IAEA and the ISIRS project of OECD/NEA are shortly reviewed. (Aoki, K.)

  14. Music therapy in cardiac health care: current issues in research.

    Science.gov (United States)

    Hanser, Suzanne B

    2014-01-01

    Music therapy is a service that has become more prevalent as an adjunct to medical practice-as its evidence base expands and music therapists begin to join the cardiology team in every phase of care, from the most serious cases to those maintaining good heart health. Although applications of music medicine, primarily listening to short segments of music, are capable of stabilizing vital signs and managing symptoms in the short-term, music therapy interventions by a qualified practitioner are showing promise in establishing deeper and more lasting impact. On the basis of mind-body approaches, stress/coping models, the neuromatrix theory of pain, and entrainment, music therapy capitalizes on the ability of music to affect the autonomic nervous system. Although only a limited number of randomized controlled trials pinpoint the efficacy of specific music therapy interventions, qualitative research reveals some profound outcomes in certain individuals. A depth of understanding related to the experience of living with a cardiovascular disease can be gained through music therapy approaches such as nonverbal music psychotherapy and guided imagery and music. The multifaceted nature of musical responsiveness contributes to strong individual variability and must be taken into account in the development of research protocols for future music therapy and music medicine interventions. The extant research provides a foundation for exploring the many potential psychosocial, physiological, and spiritual outcomes of a music therapy service for cardiology patients.

  15. Application of Computational Methods in Planaria Research: A Current Update

    Directory of Open Access Journals (Sweden)

    Ghosh Shyamasree

    2017-07-01

    Full Text Available Planaria is a member of the Phylum Platyhelminthes including flatworms. Planarians possess the unique ability of regeneration from adult stem cells or neoblasts and finds importance as a model organism for regeneration and developmental studies. Although research is being actively carried out globally through conventional methods to understand the process of regeneration from neoblasts, biology of development, neurobiology and immunology of Planaria, there are many thought provoking questions related to stem cell plasticity, and uniqueness of regenerative potential in Planarians amongst other members of Phylum Platyhelminthes. The complexity of receptors and signalling mechanisms, immune system network, biology of repair, responses to injury are yet to be understood in Planaria. Genomic and transcriptomic studies have generated a vast repository of data, but their availability and analysis is a challenging task. Data mining, computational approaches of gene curation, bioinformatics tools for analysis of transcriptomic data, designing of databases, application of algorithms in deciphering changes of morphology by RNA interference (RNAi approaches, understanding regeneration experiments is a new venture in Planaria research that is helping researchers across the globe in understanding the biology. We highlight the applications of Hidden Markov models (HMMs in designing of computational tools and their applications in Planaria decoding their complex biology.

  16. Current state of research on pressurized water reactor safety

    International Nuclear Information System (INIS)

    Couturier, Jean; Schwarz, Michel; Roubaud, Sebastien; Lavarenne, Caroline; Mattei, Jean-Marie; Rigollet, Laurence; Scotti, Oona; Clement, Christophe; Lancieri, Maria; Gelis, Celine; Jacquemain, Didier; Bentaib, Ahmed; Nahas, Georges; Tarallo, Francois; Guilhem, Gilbert; Cattiaux, Gerard; Durville, Benoit; Mun, Christian; Delaval, Christine; Sollier, Thierry; Stelmaszyk, Jean-Marc; Jeffroy, Francois; Dechy, Nicolas; Chanton, Olivier; Tasset, Daniel; Pichancourt, Isabelle; Barre, Francois; Bruna, Gianni; Evrard, Jean-Michel; Gonzalez, Richard; Loiseau, Olivier; Queniart, Daniel; Vola, Didier; Goue, Georges; Lefevre, Odile

    2018-03-01

    For more than 40 years, IPSN then IRSN has conducted research and development on nuclear safety, specifically concerning pressurized water reactors, which are the reactor type used in France. This publication reports on the progress of this research and development in each area of study - loss-of-coolant accidents, core melt accidents, fires and external hazards, component aging, etc. -, the remaining uncertainties and, in some cases, new measures that should be developed to consolidate the safety of today's reactors and also those of tomorrow. A chapter of this report is also devoted to research into human and organizational factors, and the human and social sciences more generally. All of the work is reviewed in the light of the safety issues raised by feedback from major accidents such as Chernobyl and Fukushima Daiichi, as well as the issues raised by assessments conducted, for example, as part of the ten-year reviews of safety at French nuclear reactors. Finally, through the subjects it discusses, this report illustrates the many partnerships and exchanges forged by IRSN with public, industrial and academic bodies both within Europe and internationally

  17. Current status of acid fog research. Sanseimu kenkyu no genjo

    Energy Technology Data Exchange (ETDEWEB)

    Murano, K. (National Inst. for Environmental Studies, Tsukuba (Japan))

    1993-07-10

    Acid fog research was behind in comparison with acid rain research. In case of acid fog, it is because the place generating sufficiently thick fog to collect is limited, the generating place is mountainous, its survey needs a lot of works, its collector is not convenient like in acid rain, or its sampling is difficult on its automation. Since the 1980s, an extensive survey on acid fog had been carried out centering the west coast of California, USA, and low pH fog (minimum pH 2.2) was observed. In the course of these researches, string type active fogwater collectors became a major sampling method, and the simulation of acidification of fog droplet in the atmosphere was extensively conducted. In Japan, already in the 1960s, field surveys on acid fog were conducted, in 1984 acid fog survey started on Mt. Akagi under a viewpoint of ecological impact, and there was a report that low pH fog (pH 3 to 4) continued more than 10 hours. It was pointed out that there were plant damage by acid fog in several locations, especially the tree mortality mechanism in Tomakomai was clarified. 50 refs., 10 figs., 6 tabs.

  18. Plasma Focus

    International Nuclear Information System (INIS)

    Bernard, Alain; Jolas, Alain; Garconnet, J.-P.; Mascureau, J. de; Nazet, Christian; Coudeville, Alain; Bekiarian, Andre.

    1977-01-01

    The present report is the edition of the lectures given in a conference on the Focus experiment held at the Centre d'etudes de Limeil, on Oct. 1975. After a survey of the early laboratories one will find the main results obtained in Limeil concerning interferometry, laser scattering, electric and magnetic-measurements, X-ray and neutron emission and also the possible use of explosive current generators instead of capacitor banks at high energy levels. The principal lines of future research are given in the conclusion [fr

  19. Current status of neutron activation analysis in HANARO Research Reactor

    International Nuclear Information System (INIS)

    Chung, Yong Sam; Moon, Jong Hwa; Sohn, Jae Min

    2003-01-01

    The facilities for neutron activation analysis in the HANARO (Hi-flux Advanced Neutron Application Research Reactor) are described and the main applications of NAA (Neutron Activation Analysis) are reviewed. The sample irradiation tube, automatic and manual pneumatic transfer system were installed at three irradiation holes of HANARO at the end of 1995. The performance of the NAA facility was examined to identify the characteristics of the tube transfer system, irradiation sites and custom-made polyethylene irradiation capsule. The available thermal neutron fluxes at irradiation sites are in the range of 3 x 10 13 - 1 x 10 14 n/cm 2 ·s and cadmium ratios are in 15 - 250. For an automatic sample changer for gamma-ray counting, a domestic product was designed and manufactured. An integrated computer program (Labview) to analyse the content was developed. In 2001, PGNAA (Prompt Gamma Neutron Activation Analysis) facility has been installed using a diffracted neutron beam of ST1. NAA has been applied in the trace component analysis of nuclear, geological, biological, environmental and high purity materials, and various polymers for research and development. The improvement of analytical procedures and establishment of an analytical quality control and assurance system were studied. Applied research and development for the environment, industry and human health by NAA and its standardization were carried out. For the application of the KOLAS (Korea Laboratory Accreditation Scheme), evaluation of measurement uncertainty and proficiency testing of reference materials were performed. Also to verify the reliability and to validate analytical results, intercomparison studies between laboratories were carried out. (author)

  20. [Current research situation of nephrotoxicity of Chinese herbal medicine].

    Science.gov (United States)

    Feng, Xue; Fang, Sai-Nan; Gao, Yu-Xin; Liu, Jian-Ping; Chen, Wei

    2018-02-01

    To provide the basis for the future research on the nephrotoxicity of Chinese herbal medicine through systematic and comprehensive summary of all the Chinese herbal medicines which may lead to nephrotoxicity. Foreign resources included PubMed and Cochrane library, and domestic research resources was China Food and Drug Administration(CDFA) Adverse Drug Reaction Monitoring Center database. The databases were searched from establishment to January 1, 2017. There was no limitation on research type. 28 English studies were found, including 97 Chinese herbs or prescriptions with the risk of nephrotoxicity. The following six Chinese herbal medicines with the risk of nephrotoxicity had a large number of studies: aristolochic acid(5 studies), Tripterygium wilfordii(4 studies), Erycibe obtusifolia(2 studies), Rheum palmatum(2 studies), Ephedra sinica(2 studies), and Atractylodes lances(2 studies). The remaining 91 Chinese medicines were reported with risk of nephrotoxicity in only 1 study respectively. CDFA reported 16 Chinese herbal medicines with the risk of nephrotoxicity, including Ganmaoqing Pian(capsule), Zhenju Jiangya Pian, T. wilfordii preparation, Vc-Yinqiao Pian, Chuanhuning injection, Shuanghuanglian injection, Qingkailing injection, Lianbizhi injection, herbal decoction containing Aristolochiae Radix, Guanxin Suhe Wan, Shugan Liqi Wan, Ershiwuwei Songshi Wan, herbal decoction containing Aristolochia Fangchi, herbal granules containing root of Kaempfer Dutchmanspipe, Ganmaotong(tablets), and Longdan Xiegan Wan. Currently, in addition to aristolochic acids, the most reported Chinese herbal medicine with the risk of nephrotoxicity is T. wilfordii preparation. Copyright© by the Chinese Pharmaceutical Association.

  1. Current status of neutron activation analysis in HANARO Research Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Yong Sam; Moon, Jong Hwa; Sohn, Jae Min [Korea Atomic Energy Research Institute, Daejeon (Korea)

    2003-03-01

    The facilities for neutron activation analysis in the HANARO (Hi-flux Advanced Neutron Application Research Reactor) are described and the main applications of NAA (Neutron Activation Analysis) are reviewed. The sample irradiation tube, automatic and manual pneumatic transfer system were installed at three irradiation holes of HANARO at the end of 1995. The performance of the NAA facility was examined to identify the characteristics of the tube transfer system, irradiation sites and custom-made polyethylene irradiation capsule. The available thermal neutron fluxes at irradiation sites are in the range of 3 x 10{sup 13} - 1 x 10{sup 14} n/cm{sup 2}{center_dot}s and cadmium ratios are in 15 - 250. For an automatic sample changer for gamma-ray counting, a domestic product was designed and manufactured. An integrated computer program (Labview) to analyse the content was developed. In 2001, PGNAA (Prompt Gamma Neutron Activation Analysis) facility has been installed using a diffracted neutron beam of ST1. NAA has been applied in the trace component analysis of nuclear, geological, biological, environmental and high purity materials, and various polymers for research and development. The improvement of analytical procedures and establishment of an analytical quality control and assurance system were studied. Applied research and development for the environment, industry and human health by NAA and its standardization were carried out. For the application of the KOLAS (Korea Laboratory Accreditation Scheme), evaluation of measurement uncertainty and proficiency testing of reference materials were performed. Also to verify the reliability and to validate analytical results, intercomparison studies between laboratories were carried out. (author)

  2. Focus group positioning and analysis: a commentary on adjuncts for enhancing the design of health care research.

    Science.gov (United States)

    Johnson, B C

    1990-01-01

    As health care competition increases, and as the penalties for making poor decisions become potentially more devastating, market research continues to play an increasingly important role in the decision-making process for hospitals. Concern over the appropriate use of market research and the costs related to it remains high. As such, efficiency in research design and clarity in research outcome are clearly the goals. This paper examines the focus group process and its adjunctive role in enhancing the overall design of health care market research. Specifically, the function and placement of focus groups within the research plan as well as several methods of creative focus group analysis are considered within the context of an effective research design.

  3. Japan [Marine Radioecology. Current Research and Future Scope

    International Nuclear Information System (INIS)

    Saiki, M.

    1967-01-01

    Among the present research programmes: Studies on rcidiochemical analysis of sea-water and fishes; Studies on uptake of radionuclides by marine organisms; Studies on internal exposure arising from marine products; The convenient and appropriate method of analysis and determination of radioactivity in sea— water and fishes is investigated; Biological concentration of fission products and induced products in fishes and plankton arc studied from the radioecological point of view; Contribution of radionuclides in fishes and algae to those in the total Japanese diet is studied, in connection with fall-out studies

  4. Australia [Marine Radioecology. Current Research and Future Scope

    International Nuclear Information System (INIS)

    Fry, R.M.

    1967-01-01

    Present research programme: 1.1. Investigation of the fate of radioactive nuclides introduced into a tidal estuary. 1.2. To obtain information on the eventual accumulation of radioactive nuclides in marine organisms which form part of the human food chain. 1.3. Studies are being made of the ecology of the estuarine system and the passage of selected nuclides through various trophic levels. Particular attention is being paid to oysters (Saxostrea commercialis) and stable Zn, Ca, Sr and In levels in the oysters and in estuarine water being measured to determine concentration factors for these elements in this organism

  5. Sweden [Marine Radioecology. Current Research and Future Scope

    International Nuclear Information System (INIS)

    Agnedal, P.-O.

    1967-01-01

    The research which is going on now is concentrated on a study of uptake of cobalt, zinc and iron in the food chains in brackish water. We are following different lines in this work and they can be listed as follows: A. A study of accumulation and biological half-life of cobalt (later zinc and iron) in organisms in brackish water by means of radioactive isotopes. B. Analyses of stable elements (Co, Zn and Fe) in water, algae, evertebrates and fish from different localities in the Baltic and on the Swedish West Coast

  6. Australia [Marine Radioecology. Current Research and Future Scope

    Energy Technology Data Exchange (ETDEWEB)

    Fry, R. M. [Australian Atomic Energy Commission Research Establishment, AAEC, Research Establishment, Private Mail Bag, Sutherland, N.S.W. (Australia)

    1967-03-15

    Present research programme: 1.1. Investigation of the fate of radioactive nuclides introduced into a tidal estuary. 1.2. To obtain information on the eventual accumulation of radioactive nuclides in marine organisms which form part of the human food chain. 1.3. Studies are being made of the ecology of the estuarine system and the passage of selected nuclides through various trophic levels. Particular attention is being paid to oysters (Saxostrea commercialis) and stable Zn, Ca, Sr and In levels in the oysters and in estuarine water being measured to determine concentration factors for these elements in this organism.

  7. Current situation and future of research reactor in Japan

    International Nuclear Information System (INIS)

    Metoki, Naoto

    2011-01-01

    A new style of neutron facilities coexisting high intensity pulse neutron source (J-PARC/MLF) and steady state neutron from research reactor (JRR-3) is proposed. The coexistence of the pulse and reactor source is the world trend which is inevitable for the next generation neutron science. A sophisticated management and comprehensive user program are important for Japanese neutron community, involving high performance instruments with pulse neutron and steady neutron source with widely spread users. JAEA is the most responsible for the future of neutron science, because of the commitment for both type of neutron source, J-PARC/MLF and JRR-3. (author)

  8. Current Research in Aircraft Tire Design and Performance

    Science.gov (United States)

    Tanner, J. A.; Mccarthy, J. L.; Clark, S. K.

    1981-01-01

    A review of the tire research programs which address the various needs identified by landing gear designers and airplane users is presented. The experimental programs are designed to increase tire tread lifetimes, relate static and dynamic tire properties, establish the tire hydroplaning spin up speed, study gear response to tire failures, and define tire temperature profiles during taxi, braking, and cornering operations. The analytical programs are aimed at providing insights into the mechanisms of heat generation in rolling tires and developing the tools necessary to streamline the tire design process and to aid in the analysis of landing gear problems.

  9. Current Status of Dengue Therapeutics Research and Development.

    Science.gov (United States)

    Low, Jenny G H; Ooi, Eng Eong; Vasudevan, Subhash G

    2017-03-01

    Dengue is a significant global health problem. Even though a vaccine against dengue is now available, which is a notable achievement, its long-term protective efficacy against each of the 4 dengue virus serotypes remains to be definitively determined. Consequently, drugs directed at the viral targets or critical host mechanisms that can be used safely as prophylaxis or treatment to effectively ameliorate disease or reduce disease severity and fatalities are still needed to reduce the burden of dengue. This review will provide a brief account of the status of therapeutics research and development for dengue. © The Author 2016. Published by Oxford University Press for the Infectious Diseases Society of America.

  10. [Toxoplasmosis and cancer: Current knowledge and research perspectives].

    Science.gov (United States)

    Vittecoq, M; Thomas, F

    2017-02-01

    Toxoplasmosis, caused by Toxoplasma gondii, is one of the most prevalent parasitic diseases; it is estimated to affect a third of the world's human population. Many studies showed that latent toxoplasmosis may cause in some patients significant adverse effects including schizophrenia and bipolar disorders. In addition, two recent studies highlighted a positive correlation between the prevalence of brain tumors and that of T. gondii at national and international scale. These studies are correlative, thus they do not demonstrate a causal link between T. gondii and brain tumors. Yet, they call for further research that could shed light on the possible mechanisms underlying this association.

  11. Sociocultural Behavior Influence Modelling & Assessment: Current Work and Research Frontiers.

    Energy Technology Data Exchange (ETDEWEB)

    Bernard, Michael Lewis [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2018-01-01

    A common problem associated with the effort to better assess potential behaviors of various individuals within different countries is the shear difficulty in comprehending the dynamic nature of populations, particularly over time and considering feedback effects. This paper discusses a theory-based analytical capability designed to enable analysts to better assess the influence of events on individuals interacting within a country or region. These events can include changes in policy, man-made or natural disasters, migration, war, or other changes in environmental/economic conditions. In addition, this paper describes potential extensions of this type of research to enable more timely and accurate assessments.

  12. Puerto Rico [Marine Radioecology. Current Research and Future Scope

    International Nuclear Information System (INIS)

    Lowman, Frank G.

    1967-01-01

    Present research programme: Marine biology programme (marine biogeochemistry). The programme is designed to provide measurements of the distribution and movements of selected trace elements in a restricted but complete ecological and biogeochemical system. To obtain information on interactions between the marine biosphere and hydrosphere, measurements are being made of biological productivity, amounts of trace elements in the organisms and the environment, biological half-lives of trace elements, characteristics of food webs, and the influence of physical and chemical oceanographic factors upon the distribution patterns of trace elements in the marine waters, organisms and sediments offshore from the west coast of Puerto Rico

  13. The need for a behavioural science focus in research on mental health and mental disorders.

    Science.gov (United States)

    Wittchen, Hans-Ulrich; Knappe, Susanne; Andersson, Gerhard; Araya, Ricardo; Banos Rivera, Rosa M; Barkham, Michael; Bech, Per; Beckers, Tom; Berger, Thomas; Berking, Matthias; Berrocal, Carmen; Botella, Christina; Carlbring, Per; Chouinard, Guy; Colom, Francesc; Csillag, Claudio; Cujipers, Pim; David, Daniel; Emmelkamp, Paul M G; Essau, Cecilia A; Fava, Giovanni A; Goschke, Thomas; Hermans, Dirk; Hofmann, Stefan G; Lutz, Wolfgang; Muris, Peter; Ollendick, Thomas H; Raes, Filip; Rief, Winfried; Riper, Heleen; Tossani, Eliana; van der Oord, Saskia; Vervliet, Bram; Haro, Josep M; Schumann, Gunter

    2014-01-01

    Psychology as a science offers an enormous diversity of theories, principles, and methodological approaches to understand mental health, abnormal functions and behaviours and mental disorders. A selected overview of the scope, current topics as well as strength and gaps in Psychological Science may help to depict the advances needed to inform future research agendas specifically on mental health and mental disorders. From an integrative psychological perspective, most maladaptive health behaviours and mental disorders can be conceptualized as the result of developmental dysfunctions of psychological functions and processes as well as neurobiological and genetic processes that interact with the environment. The paper presents and discusses an integrative translational model, linking basic and experimental research with clinical research as well as population-based prospective-longitudinal studies. This model provides a conceptual framework to identify how individual vulnerabilities interact with environment over time, and promote critical behaviours that might act as proximal risk factors for ill-health and mental disorders. Within the models framework, such improved knowledge is also expected to better delineate targeted preventive and therapeutic interventions that prevent further escalation in early stages before the full disorder and further complications thereof develop. In contrast to conventional "personalized medicine" that typically targets individual (genetic) variation of patients who already have developed a disease to improve medical treatment, the proposed framework model, linked to a concerted funding programme of the "Science of Behaviour Change", carries the promise of improved diagnosis, treatment and prevention of health-risk behaviour constellations as well as mental disorders. Copyright © 2013 John Wiley & Sons, Ltd.

  14. RNA sequencing: current and prospective uses in metabolic research.

    Science.gov (United States)

    Vikman, Petter; Fadista, Joao; Oskolkov, Nikolay

    2014-10-01

    Previous global RNA analysis was restricted to known transcripts in species with a defined transcriptome. Next generation sequencing has transformed transcriptomics by making it possible to analyse expressed genes with an exon level resolution from any tissue in any species without any a priori knowledge of which genes that are being expressed, splice patterns or their nucleotide sequence. In addition, RNA sequencing is a more sensitive technique compared with microarrays with a larger dynamic range, and it also allows for investigation of imprinting and allele-specific expression. This can be done for a cost that is able to compete with that of a microarray, making RNA sequencing a technique available to most researchers. Therefore RNA sequencing has recently become the state of the art with regards to large-scale RNA investigations and has to a large extent replaced microarrays. The only drawback is the large data amounts produced, which together with the complexity of the data can make a researcher spend far more time on analysis than performing the actual experiment. © 2014 Society for Endocrinology.

  15. Gravitational-wave research: Current status and future prospects

    International Nuclear Information System (INIS)

    Thorne, K.S.

    1980-01-01

    There is a reasonably good change that in the 1980s cosmic gravitational waves will be discovered and will become a powerful tool for astronomy. This prospect has stimulated a three-pronged research effort. First, relativity theorists are developing new mathematical tools for the analysis of gravitational radiation: including (i) methods of analyzing the generation of gravity waves by sources with strong self-gravity and large internal velocities (e.g., collisions of black holes), (ii) methods of computing radiation reaction in sources, and (iii) methods of analyzing how gravitational waves propagate through our lumpy curved-space Universe. Second, astrophysicists are attempting to identify the most promissing sources of gravitational waves, and are using the relativity theorists' mathematical tools to estimate the characteristics of the waves they emit. Third, with the estimated wave characteristics in mind, experimenters are designing and constructing a second generation of gravitational-wave detectors: detectors of three types: Doppler tracking of interplanetary spacecraft, Earth-based laser interferometers, and Earth-based Weber-type resonant bars. This article reviews, in brief, all three prongs of the research effort and gives references to more detailed articles about specialized aspects of gravitational-wave physics

  16. Candidate genes for COPD: current evidence and research

    Directory of Open Access Journals (Sweden)

    Kim WJ

    2015-10-01

    Full Text Available Woo Jin Kim,1 Sang Do Lee2 1Department of Internal Medicine and Environmental Health Center, Kangwon National University, Chuncheon, 2Department of Pulmonary and Critical Care Medicine, Clinical Research Center for Chronic Obstructive Airway Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea Abstract: COPD is a common complex disease characterized by progressive airflow limitation. Several genome-wide association studies (GWASs have discovered genes that are associated with COPD. Recently, candidate genes for COPD identified by GWASs include CHRNA3/5 (cholinergic nicotine receptor alpha 3/5, IREB2 (iron regulatory binding protein 2, HHIP (hedgehog-interacting protein, FAM13A (family with sequence similarity 13, member A, and AGER (advanced glycosylation end product–specific receptor. Their association with COPD susceptibility has been replicated in multiple populations. Since these candidate genes have not been considered in COPD, their pathological roles are still largely unknown. Herein, we review some evidences that they can be effective drug targets or serve as biomarkers for diagnosis or subtyping. However, more study is required to understand the functional roles of these candidate genes. Future research is needed to characterize the effect of genetic variants, validate gene function in humans and model systems, and elucidate the genes’ transcriptional and posttranscriptional regulatory mechanisms. Keywords: chronic obstructive pulmonary disease, genetics, genome-wide association study

  17. 2002–2012: 10 Years of Research Progress in Horizontal-Axis Marine Current Turbines

    Directory of Open Access Journals (Sweden)

    Kai-Wern Ng

    2013-03-01

    Full Text Available Research in marine current energy, including tidal and ocean currents, has undergone significant growth in the past decade. The horizontal-axis marine current turbine is one of the machines used to harness marine current energy, which appears to be the most technologically and economically viable one at this stage. A number of large-scale marine current turbines rated at more than 1 MW have been deployed around the World. Parallel to the development of industry, academic research on horizontal-axis marine current turbines has also shown positive growth. This paper reviews previous research on horizontal-axis marine current turbines and provides a concise overview for future researchers who might be interested in horizontal-axis marine current turbines. The review covers several main aspects, such as: energy assessment, turbine design, wakes, generators, novel modifications and environmental impact. Future trends for research on horizontal-axis marine current turbines are also discussed.

  18. Participatory design in Parkinson's research with focus on the symptomatic domains to be measured.

    Science.gov (United States)

    Serrano, J Artur; Larsen, Frank; Isaacs, Tom; Matthews, Helen; Duffen, Joy; Riggare, Sara; Capitanio, Fulvio; Ferreira, Joaquim J; Domingos, Josefa; Maetzler, Walter; Graessner, Holm

    2015-01-01

    There is a growing interest in the objective assessment of health related outcomes using technology providing quality measurements to be applied not only in daily clinical practice, but also in scientific research. Differences in the understandings of the condition and the terminology used between people with Parkinson's (PwPs), clinicians and technical developers may influence the progress of a participatory design process. This paper reports on a participatory design process to achieve a consensus among PwPs, clinicians and technologists over the selection of a set of symptomatic domains to be continuously assessed, in order to provide results relevant to both PwPs and clinicians. The methods used were a Web based user survey, end-user focus groups, ranking by combined methods, a Delphi process performed among clinicians and scientists, and prioritization of the results in a concertation workshop for PwPs, clinicians and technologists. The following symptomatic domains were commonly agreed by PwPs and clinicians to be of central importance in a system of continuous assessment: hypokinesia/bradykinesia, tremor, sway, gait, sleep and cognition. This list satisfied both the needs of the PwPs and the concerns of the clinicians regarding the means of advancing new strategies in assessment and interventions in PD. A participatory design strategy allowed the definition of a consensual list of symptomatic domains. Both the strategy and the achieved results may be of relevance for similar interdisciplinary approaches in the field of PD using a participatory design involving patients, clinicians and technologists.

  19. Development of X-ray and ion diagnostic methods for plasma focus research

    International Nuclear Information System (INIS)

    Sadowski, M.

    1986-12-01

    A review of experimental methods used for investigation of X-rays and ion-beams emmited from plasma focus facilities is presented. The research program has been realized at the Institute for Nuclear Studies in Swierk and at the Institut fuer Plasmaforschung in Stuttgart, within the frames of an international co-operation. The studies on ion emission from different PF facilities are reviewed. The application of CN-films with Al-filters and of different ion-pinhole cameras is described. The use of a Thomson mass-spectrometer adopted for plasma studies is presented. The time-resolved measurements combined with a simultaneous mass- and energy-analysis of the ion beams are also described. The most important results of these studies are summarized. Particular attention is also paid to the studies of the X-ray emission. The use of stereoscopic sets of vacuum pinhole cameras with thin Be-filters is described. The application of X-ray pinhole cameras equipped with miniature scintillators for time-resolved measurements is also presented. The most important results of the X-ray emission studies are summarized. 35 refs., 12 figs. (author)

  20. Lunar e-Library: A Research Tool Focused on the Lunar Environment

    Science.gov (United States)

    McMahan, Tracy A.; Shea, Charlotte A.; Finckenor, Miria; Ferguson, Dale

    2007-01-01

    As NASA plans and implements the Vision for Space Exploration, managers, engineers, and scientists need lunar environment information that is readily available and easily accessed. For this effort, lunar environment data was compiled from a variety of missions from Apollo to more recent remote sensing missions, such as Clementine. This valuable information comes not only in the form of measurements and images but also from the observations of astronauts who have visited the Moon and people who have designed spacecraft for lunar missions. To provide a research tool that makes the voluminous lunar data more accessible, the Space Environments and Effects (SEE) Program, managed at NASA's Marshall Space Flight Center (MSFC) in Huntsville, AL, organized the data into a DVD knowledgebase: the Lunar e-Library. This searchable collection of 1100 electronic (.PDF) documents and abstracts makes it easy to find critical technical data and lessons learned from past lunar missions and exploration studies. The SEE Program began distributing the Lunar e-Library DVD in 2006. This paper describes the Lunar e-Library development process (including a description of the databases and resources used to acquire the documents) and the contents of the DVD product, demonstrates its usefulness with focused searches, and provides information on how to obtain this free resource.

  1. Traditional, complementary, and alternative medicine: Focusing on research into traditional Tibetan medicine in China.

    Science.gov (United States)

    Song, Peipei; Xia, Jufeng; Rezeng, Caidan; Tong, Li; Tang, Wei

    2016-07-19

    As a form of traditional, complementary, and alternative medicine (TCAM), traditional Tibetan medicine has developed into a mainstay of medical care in Tibet and has spread from there to China and then to the rest of the world. Thus far, research on traditional Tibetan medicine has focused on the study of the plant and animal sources of traditional medicines, study of the histology of those plants and animals, chemical analysis of traditional medicines, pharmacological study of those medicines, and evaluation of the clinical efficacy of those medicines. A number of papers on traditional Tibetan medicines have been published, providing some evidence of the efficacy of traditional Tibetan medicine. However, many traditional Tibetan medicines have unknown active ingredients, hampering the establishment of drug quality standards, the development of new medicines, commercial production of medicines, and market availability of those medicines. Traditional Tibetan medicine must take several steps to modernize and spread to the rest of the world: the pharmacodynamics of traditional Tibetan medicines need to be determined, the clinical efficacy of those medicines needs to be verified, criteria to evaluate the efficacy of those medicines need to be established in order to guide their clinical use, and efficacious medicines need to be acknowledged by the pharmaceutical market. The components of traditional Tibetan medicine should be studied, traditional Tibetan medicines should be screened for their active ingredients, and techniques should be devised to prepare and manufacture those medicines.

  2. Utilizing Dietary Micronutrient Ratios in Nutritional Research May be More Informative than Focusing on Single Nutrients

    Directory of Open Access Journals (Sweden)

    Owen J. Kelly

    2018-01-01

    Full Text Available The 2015 US dietary guidelines advise the importance of good dietary patterns for health, which includes all nutrients. Micronutrients are rarely, if ever, consumed separately, they are not tissue specific in their actions and at the molecular level they are multitaskers. Metabolism functions within a seemingly random cellular milieu however ratios are important, for example, the ratio of adenosine triphosphate to adenosine monophosphate, or oxidized to reduced glutathione. Health status is determined by simple ratios, such as the waist hip ratio, or ratio of fat mass to lean mass. Some nutrient ratios exist and remain controversial such as the omega-6/omega-3 fatty acid ratio and the sodium/potassium ratio. Therefore, examining ratios of micronutrients may convey more information about how diet and health outcomes are related. Summarized micronutrient intake data, from food only, from the National Health and Nutrition Examination Survey, were used to generate initial ratios. Overall, in this preliminary analysis dietary ratios of micronutrients showed some differences between intakes and recommendations. Principles outlined here could be used in nutritional epidemiology and in basic nutritional research, rather than focusing on individual nutrient intakes. This paper presents the concept of micronutrient ratios to encourage change in the way nutrients are regarded.

  3. Building a science of partnership-focused research: forging and sustaining partnerships to support child mental health prevention and services research.

    Science.gov (United States)

    Bradshaw, Catherine P; Haynes, Katherine Taylor

    2012-07-01

    Building on growing interest in translational research, this paper provides an overview of a special issue of Administration and Policy in Mental Health and Mental Health Service Research, which is focused on the process of forging and sustaining partnerships to support child mental health prevention and services research. We propose that partnership-focused research is a subdiscipline of translational research which requires additional research to better refine the theoretical framework and the core principles that will guide future research and training efforts. We summarize some of the major themes across the eight original articles and three commentaries included in the special issue. By advancing the science of partnership-focused research we will be able to bridge the gap between child mental health prevention and services research and practice.

  4. Current status and outlook of pancreatic islets transplantation research

    International Nuclear Information System (INIS)

    Wang Wei; Ye Bin

    2006-01-01

    Diabetes is a common disease, severely harmful to the human's health and life quality. The pancreatic islets transplantation can correct the patient's hyperglycemia, stop or even reverse the progress of the complication and thus decrease the mortality of diabetic patients. It is the most safe and efficient therapy for diabetes. Since the Edmonton Protocol got success in pancreatic islet transplantation in 2000, it has been more and more interested because of its great clinical curative effect. Research strategy of islet transplantation is now focussed on increasing the acquired islets with normal viability, selecting the best transplantation pathway, and improving the immunosuppression protocol. The shortage of human pancreatic donor is an ever unsolved problem in clinical application. The potential resolutions may include acquisition from xenogenic-islets; islets originated from stem cells, and islets from the living-donor human pancreas. The islets transplantation will open a new application field for interventional radiology. (authors)

  5. Mexican medicinal plants with anxiolytic or antidepressant activity: Focus on preclinical research.

    Science.gov (United States)

    López-Rubalcava, Carolina; Estrada-Camarena, Erika

    2016-06-20

    Anxiety and depression are considered the most prevalent psychiatric disorders worldwide. In Mexico, the use of medicinal plants to alleviate the symptoms associated with these psychiatric disorders is increasing. However, there is little scientific evidence that validates the efficacy of these plants. This evidence needs to be critically revised, and further studied to provided scientific support for their use. To identify the plants that are used in Mexico for the treatment of disorders related to anxiety and depression, and to review the current preclinical and when available, clinical information of these plants. We searched in scientific databases (Pubmed, Web of Science, Scopus and other web sources such as "Biblioteca digital de la medicina tradicional Mexicana" ) for Mexican plants used for the treatment of anxiety and depression that have been analyzed in preclinical studies. Additional information was obtained from published books. For this review, we also consider those plants used in Mexican traditional medicine for the treatment of "nervios," "susto" or "espanto;" common terms that describe symptoms related to anxiety and depression disorders. The bibliographic search identified 49 plants used in Mexican traditional medicine for the treatment of disorders related to anxiety and depression. From all these plants, 59% were analyzed in preclinical research, and only 8% were tested in clinical studies; only a few of these studies tried to elucidate their mechanism of action. In general, it is proposed that the plant extracts interact with the GABAergic system. However, only part of these studies attempted to analyze other neurotransmitter systems. Finally, in some cases, drug-herbal interactions were reported. There is a large number of Mexican medicinal plants used as a treatment for anxiety and depression disorders. Although some of these plants have been studied in preclinical research, in most cases these studies are preliminary, and the understanding

  6. Current Translational Research and Murine Models For Duchenne Muscular Dystrophy

    Science.gov (United States)

    Rodrigues, Merryl; Echigoya, Yusuke; Fukada, So-ichiro; Yokota, Toshifumi

    2016-01-01

    Duchenne muscular dystrophy (DMD) is an X-linked genetic disorder characterized by progressive muscle degeneration. Mutations in the DMD gene result in the absence of dystrophin, a protein required for muscle strength and stability. Currently, there is no cure for DMD. Since murine models are relatively easy to genetically manipulate, cost effective, and easily reproducible due to their short generation time, they have helped to elucidate the pathobiology of dystrophin deficiency and to assess therapies for treating DMD. Recently, several murine models have been developed by our group and others to be more representative of the human DMD mutation types and phenotypes. For instance, mdx mice on a DBA/2 genetic background, developed by Fukada et al., have lower regenerative capacity and exhibit very severe phenotype. Cmah-deficient mdx mice display an accelerated disease onset and severe cardiac phenotype due to differences in glycosylation between humans and mice. Other novel murine models include mdx52, which harbors a deletion mutation in exon 52, a hot spot region in humans, and dystrophin/utrophin double-deficient (dko), which displays a severe dystrophic phenotype due the absence of utrophin, a dystrophin homolog. This paper reviews the pathological manifestations and recent therapeutic developments in murine models of DMD such as standard mdx (C57BL/10), mdx on C57BL/6 background (C57BL/6-mdx), mdx52, dystrophin/utrophin double-deficient (dko), mdxβgeo, Dmd-null, humanized DMD (hDMD), mdx on DBA/2 background (DBA/2-mdx), Cmah-mdx, and mdx/mTRKO murine models. PMID:27854202

  7. Current Research at the Endeavour Ridge 2000 Integrated Studies Site

    Science.gov (United States)

    Butterfield, D. A.; Kelley, D. S.; Ridge 2000 Community, R.

    2004-12-01

    Integrated geophysical, geological, chemical, and biological studies are being conducted on the Endeavour segment with primary support from NSF, the W.M. Keck Foundation, and NSERC (Canada). The research includes a seismic network, physical and chemical sensors, high-precision mapping and time-series sampling. Several research expeditions have taken place at the Endeavour ISS in the past year. In June 2003, an NSF-sponsored cruise with R.V. al T.G.Thompson/ROV al Jason2 installed microbial incubators in drill-holes in the sides of active sulfide chimneys and sampled rocks, fluids, and microbes in the Mothra and Main Endeavour Field (MEF). In July 2003, with al Thompson/Jason2, an NSF-LEXEN project at Baby Bare on Endeavour east flank conducted sampling through seafloor-penetrating probes, plus time-series sampling of fluids, microbes, and rocks at the MEF. In September 2003, with al Thompson/ROV al ROPOS, the Keck Proto-Neptune project installed a seismic network consisting of 1 broadband and 7 short-period seismometers, installation of chemical/physical sensors and time-series samplers for chemistry and microbiology in the MEF and Clam Bed sites, collection of rocks, fluids, animals, and microbes. In May/June 2004, an NSF-sponsored al Atlantis/Alvin cruise recovered sulfide incubators installed in 2003, redeployed a sulfide incubator, mapped MEF and Mothra vent fields with high-resolution Imagenix sonar, sampled fluids from MEF, Mothra, and Clam Bed, recovered year-long time-series fluid and microbial samplers from MEF and Clam Bed, recovered and installed hot vent temperature-resistivity monitors, cleaned up the MEF and deployed new markers at major sulfide structures. In August 2004, there were two MBARI/Keck-sponsored cruises with R.V. al Western Flyer/ROV al Tiburon. The first cruise completed the seismic network with addition of two more broadband seismometers and serviced all 7 short-period seismometers. al Tiburon then performed microbial and chemical

  8. Israel [Marine Radioecology. Current Research and Future Scope

    International Nuclear Information System (INIS)

    Gilat, E.; Steiger-Shafrir, N.H.

    1967-01-01

    Present research programme - Radioactive contamination in marine environment and biota in the eastern Mediterranean. Detail of programme: (1) Objectives and most important points: The study of radioactive contamination of marine environment and biota involved qualitative and quantitative determinations for radionuclides of biological interest. The purpose of such an investigation is to determine; (a) Rate of passage of radionuclides through the food chain to the human organism in subtropical conditions prevailing in the eastern Mediterranean. The Levantine Basin of the Mediterranean is characterized by high temperatures and salinities which are typical for a tropical area. These are the cause of survival and development of numerous Indo-Pacific organisms which penetrate from the Red Sea through the Suez Canal into the eastern Mediterranean. It is therefore of interest to determine concentrations of radionuclides taken up by the endemic as well as the Indo-Pacific species at various levels of the food chain, (b) Indicator organisms which can be used in measuring the concentration of radionuclides in marine environment. (c) Effect of organisms on the distribution of elements in the sea. The elements, of which a large proportion passes through the organisms, will thus undergo a modification in their spatial and seasonal distribution in the water and sediments

  9. Current practices and research updates on diabetes mellitus in canine

    Directory of Open Access Journals (Sweden)

    Pankaj Kumar

    2014-11-01

    Full Text Available Diabetes has evidence in ancient literatures, though recently is being considered as one amongst the most emerging disease condition in both human and companion animals. Diabetes mellitus is one of the common endocrinopathy of dog characterized by hyperglycemia, glycosuria and weight loss. Reports suggests high fraction of canine population suffer with diabetes world over. Studies in different veterinary hospitals of United States suggest increase in cases of canine diabetes and decrease in case fatality rate over time. Increase in cases of canine diabetes worldwide is attributed to awareness amongst pet owners, better veterinary health facilities, breed preferences by dog owners, increase dependence on commercial feeds, obesity, etc. Diabetes in most dogs is immune mediated and insulin dependent. Breed predisposition in canine is attributed to dog leukocyte antigen gene pool encoding form major histocompatibility complex-II molecules, however research is still underway. Diagnosis of diabetes still relies on blood sugar evaluation for screening of canine population, though many other diagnostic methods have shown promising benefits including measurement of fructosamine and glycated haemoglobin. Management of diabetes in dog is based on insulin therapy, diet modification and exercise. Use of oral anti-diabetics drugs in canine is limited though experimental studies have shown promising results. Alternative therapies have been explored, but only a few approaches have shown promise for clinical application.

  10. Current and future directions in culture and happiness research.

    Science.gov (United States)

    Oishi, Shigehiro; Gilbert, Elizabeth A

    2016-04-01

    Once believed to be universal, a growing body of research shows that both the conception and predictors of happiness vary cross-culturally. First, the meaning and importance of happiness varies both across time and between nations. Americans, for instance, tend to define happiness in terms of pleasure or enjoyment and view happiness as universally positive, whereas East Asian and Middle Eastern cultures may highlight the transient and socially disruptive nature of happiness and be ambivalent about whether it is good. Second, predictors of happiness vary between cultures. Recent work highlights new mediators (e.g., relational mobility), individual predictors (e.g., person-culture fit), societal factors (e.g., good governance and wealth), within-culture variations (e.g., at the state or city level), and interventions (e.g., practicing gratitude) that differ cross-culturally or help explain cultural differences in happiness. Though many questions remain, this review highlights how these recent advances broaden and revise our understanding of culture and happiness. Copyright © 2015 Elsevier Ltd. All rights reserved.

  11. Strongyloidiasis Current Status with Emphasis in Diagnosis and Drug Research

    Directory of Open Access Journals (Sweden)

    Tiago Mendes

    2017-01-01

    Full Text Available Strongyloidiasis is a parasitic neglected disease caused by the nematode Strongyloides stercoralis affecting 30 to 100 million people worldwide. Complications, strongly associated with alcoholism, organ transplants, and HTLV-1 virus, often arise due to late diagnosis, frequently leading to patient death. Lack of preemptive diagnosis is not the only difficulty when dealing with this parasite, since there are no gold standard diagnostic techniques, and the ones used have problems associated with sensitivity, resulting in false negatives. Treatment is also an issue as ivermectin and benzimidazoles administration leads to inconsistent cure rates and several side effects. Researching new anti-Strongyloides drugs is a difficult task since S. stercoralis does not develop until the adult stages in Mus musculus (with the exception of SCID mice, the main experimental host model. Fortunately, alternative parasite models can be used, namely, Strongyloides ratti and S. venezuelensis. However, even with these models, there are other complications in finding new drugs, which are associated with specific in vitro assay protocol steps, such as larvae decontamination. In this review, we highlight the challenges associated with new drug search, the compounds tested, and a list of published in vitro assay methodologies. We also point out advances being made in strongyloidiasis diagnosis so far.

  12. Using ASM Podcasts to Excite Undergraduate Students about Current Microbiological Research

    Directory of Open Access Journals (Sweden)

    Stacey E. Lettini

    2014-08-01

    Full Text Available Innovative technology is often used as a mechanism to engage students in and out of the classroom and can be used to increase critical thinking skills. Podcasts are an excellent way to introduce students to current topics and research in microbiology. The American Society for Microbiology (ASM produces three podcasts that are microbiologically focused: This Week in Microbiology (TWiM, This Week in Parasitology (TWiP, and This Week in Virology (TWiV. These podcasts are usually presented in a manner similar to a journal club, as the presenters regularly invite guests to discuss current research papers. Since students often find reading scientific literature difficult and get bogged down in the details rather than seeing the over-arching purpose of a paper, these podcasts have been used in a General Microbiology course to introduce recent research articles. The students were first assigned an original research article to read and review, and they were asked to generate questions pertaining to things they did not understand. Next, students listened to the corresponding podcast that discussed the article and used it to answer their questions. This was followed by a classroom discussion of the article and the podcast. The ASM podcast helped to demystify original research by providing details of the experimental design and presentation of the results in a language that is more casual and relatable. Students demonstrated greater critical thinking and comprehension of microbiology literature after listening to the podcast. This activity can be used in a variety of courses in the biology curriculum.

  13. Soil Contamination and Remediation Strategies. Current research and future challenge

    Science.gov (United States)

    Petruzzelli, G.

    2012-04-01

    eliminating the source of pollution, but also on blocking the pathways from contaminants to receptors or reducing the exposure to contaminants,. Future challenge integration of sustainability into remediation decision-making. Soil is not a waste! There is a growing interest in the clean up approaches that maintain soil quality after remediation treatments. This issue is of great importance in the U.S.A. where the EPA from 2009 is promoting innovative clean-up strategies (Green Remediation). Green remediation is defined as the practice of considering all environmental effects of remedy and incorporating options to maximize environmental benefit of cleanup actions . These remediation strategies restore contaminated sites to productive use with a great attention to the global environmental quality, including the preservation of soil functionality according to the following principles: use minimally invasive technologies; use passive energy technologies such as bioremediation and phytoremediation as primary remedies or finishing steps where possible and effective; minimize soil and habitat disturbance; minimize bioavailability of contaminants trough adequate contaminant source and plume control If we move from the current definition of remedial targets based on total concentrations, technologies with low impact on the environment can be utilized reducing the wrong choice to disposal soil in landfill destroying quickly a not renewable essential resource.

  14. Focus on the research utility of intravascular ultrasound - comparison with other invasive modalities

    Directory of Open Access Journals (Sweden)

    Hoye Angela

    2011-01-01

    Full Text Available Abstract Intravascular ultrasound (IVUS is an invasive modality which provides cross-sectional images of a coronary artery. In these images both the lumen and outer vessel wall can be identified and accurate estimations of their dimensions and of the plaque burden can be obtained. In addition, further processing of the IVUS backscatter signal helps in the characterization of the type of the plaque and thus it has been used to study the natural history of the atherosclerotic evolution. On the other hand its indigenous limitations do not allow IVUS to assess accurately stent struts coverage, existence of thrombus or exact site of plaque rupture and to identify some of the features associated with increased plaque vulnerability. In order this information to be obtained, other modalities such as optical coherence tomography, angioscopy, near infrared spectroscopy and intravascular magnetic resonance imaging have either been utilized or are under evaluation. The aim of this review article is to present the current utilities of IVUS in research and to discuss its advantages and disadvantages over the other imaging techniques.

  15. The role of care in nutrition programmes: current research and a research agenda.

    Science.gov (United States)

    Engle, P L; Bentley, M; Pelto, G

    2000-02-01

    The importance of cultural and behavioural factors in children's nutrition, particularly with regard to feeding, has been recognized only recently. The combination of evidence regarding the importance of caregiving behaviour for good nutrition, and improved strategies for measuring behaviour have led to a renewed interest in care. The UNICEF conceptual framework suggests that care, in addition to food security and health care services, are critical for children's survival, growth and development. The present paper focuses on the care practice of complementary feeding, specifically behavioural factors such as parental interaction patterns, feeding style and adaptation of feeding to the child's motor abilities (self-feeding or feeding by others). Three kinds of feeding styles (Birch & Fisher, 1995) are identified: controlling; laissez-faire; responsive. Probable effects of each feeding style on nutrient intake are described. A number of studies of feeding behaviour have suggested that the laissez-faire style is most frequently observed among families and communities with a higher prevalence of malnourished children. Nutrition interventions that have been able to show significant effects on outcomes, such as the Hearth Model in Vietnam (Sternin et al. 1997), have usually incorporated behavioural components in their intervention. At this time, there have been no tests of the efficacy of behavioural interventions to improve feeding practices. Research is needed to understand behavioural factors in complementary feeding, and to identify and test intervention strategies designed to improve nutrient intake of young children. Finally, the paper concludes with a discussion of how nutrition programmes might change if care were incorporated.

  16. Energy conversion and concentration in a high-current gaseous discharge: Dense plasma spheromak in plasma focus experiments

    International Nuclear Information System (INIS)

    Kukushkin, A.B.; Rantsev-Kartinov, V.A.; Terentiev, A.R.

    1995-01-01

    Experimental results are presented which verify the possibility of the self-generated transformation of the magnetic field in plasma focus discharges to give a closed, spheromak-like magnetic configuration (SLMC). The energy conversion mechanism suggests a possibility of further concentrating the plasma power density by means of natural compressing the SLMC-trapped plasma by the residual magnetic field of the plasma focus discharge

  17. Family Literacy and Second Language Literacy Research: Focus on Language Minority Children

    Directory of Open Access Journals (Sweden)

    Özgür Yıldırım

    2013-04-01

    Full Text Available Problem Statement: Countries like the U. S. A. or Canada have citizens from various ethnic backgrounds. Although English is the dominant language in many parts of these countries, immigrants generally prefer speaking their native language when they are in their homes. Whatever the reason for using native language at home is, when we consider the children in these families, we can say that being exposed to different languages at home and at school may be a problem for their language development.Purpose of Study: There are many studies conducted in order to better understand the problems of language minority children. A great deal of literature on language minority students focuses on the ties between these children‟s literacy development and their literacy practices at home. In other words, these studies aim to see how the literacy events these children are exposed to at home affect their literacy learning in the second language.Methods: This paper is an attempt to put together and discuss various theoretical and empirical studies conducted on the literacy development of language minority children in English speaking countries.Findings: Literacy education of language minority students is not an easy task. It is very complicated and difficult to achieve as it requires a complete collaboration among all the responsible parties (teachers, families, researchers, education policy makers, school administrators. Conclusion and Recommendations: Successful collaboration among all the involved parties would bring successful outcomes in terms of children‟s healthy literacy development. The collaboration between teachers and families is the most vital one because these two parties are the ones that have one-to-one interaction with children.

  18. Focus Groups in Qualitative Research: Culturally Sensitive Methodology for the Arabian Gulf?

    Science.gov (United States)

    Thomas, Andrew

    2008-01-01

    This article explores whether focus groups can constitute a culturally sensitive method of data gathering for educational leadership, management and related areas in a Gulf-Arab cultural context. Reviewing the literature on focus groups and cross-cultural psychology for the Arab region, it identifies key notions related to societal values such as…

  19. The need for mental health services research focusing on poor young women.

    Science.gov (United States)

    Miranda, Jeanne; Green, Bonnie L.

    1999-06-01

    to be learned about the mental health status and needs of poor women, along with the impact of loss of public support on their physical and mental health. Access to mental health care within a managed care setting also needs to be addressed, and care taken to understand the particular needs of poor populations that will actually make these services accessible to them. Insufficient attention has thus far been paid to the cost implications of providing these services to the poor. While providing treatment is associated with significant costs, the costs of not providing care, especially the effects of depression on offspring, should not be overlooked. CHALLENGES TO EXAMINING MENTAL HEALTH IN POOR WOMEN: A number of suggestions were made for addressing practical and methodological challenges to providing mental health services. These include placing services for these individuals within their familiar medical settings, which requires close working relationships between psychiatric and medical personnel within these settings. Outreach is a necessary part of getting poor women into treatment, and should be a routine part of helping women become engaged with caregivers. Providing culturally sensitive treatments is an important focus too, through developing knowledge about the culturally based customs and expectations of target groups. Measurement issues need to be attended to, as most research instruments have been developed on middle class populations, and have not been examined for their psychometric properties and norms in less advantaged groups. Careful translation techniques are also required. Finally, working with institutions sponsoring research to educate them about special problems and challenges with these groups will help improve the quality and efficiency of the work accomplished.

  20. A review study of the current research on energy hub for energy positive neighborhoods

    NARCIS (Netherlands)

    Walker, S.W.W.; Labeodan, T.; Maassen, W.H.; Zeiler, W.

    2017-01-01

    Energy positive neighborhoods and cities are emerging concepts aimed at addressing the current energy and environmental sustainability challenges. In this paper, the concept and current research on energy hubs relating to energy positive neighborhoods are presented. In addition to discussing

  1. Ocean Science for Decision-Making: Current Activities of the National Research Council's Ocean Studies Board

    Science.gov (United States)

    Roberts, S.; Glickson, D.; Mengelt, C.; Forrest, S.; Waddell, K.

    2012-12-01

    The National Research Council is a private, nonprofit organization chartered by Congress in 1916 as an expansion of the U.S. National Academy of Sciences. Its mission is to improve the use of science in government decision making and public policy, increase public understanding, and promote the acquisition and dissemination of knowledge in matters involving science, engineering, technology, and health. Within the National Research Council, the Ocean Studies Board (OSB) mission is to explore the science, policies, and infrastructure needed to understand, manage, and conserve coastal and marine environments and resources. OSB undertakes studies and workshops on emerging scientific and policy issues at the request of federal agencies, Congress, and others; provides program reviews and guidance; and facilitates communication on oceanographic issues among different sectors. OSB also serves as the U.S. National Committee to the international, nongovernmental Scientific Committee on Oceanic Research (SCOR). OSB has produced reports on a wide range of topics of interest to researchers and educators, the federal government, the non-profit sector, and industry. Recent reports have focused on ecosystem services in the Gulf of Mexico after the Deepwater Horizon oil spill, sea level rise on the U.S. west coast, scientific ocean drilling needs and accomplishments, requirements for sustained ocean color measurements, critical infrastructure for ocean research, tsunami warning and preparedness, ocean acidification, and marine and hydrokinetic power resource assessments. Studies that are currently underway include responding to oil spills in the Arctic, evaluating the effectiveness of fishery stock rebuilding plans, and reviewing the National Ocean Acidification Research Plan. OSB plays an important role in helping create policy decisions and disseminating important information regarding various aspects of ocean science.

  2. Focus on sex differences in grant applications submitted to the Netherlands Organization for Health Research and Development

    NARCIS (Netherlands)

    Keuken, Debby G.; Haafkens, Joke A.; Klazinga, Niek S.

    2007-01-01

    ABSTRACT: BACKGROUND: Several measures have been implemented at international level to ensure that there is a greater focus on sex differences in health research. This study evaluates the effect of various formal incentives that were introduced by a Dutch financer of health research to encourage

  3. Longitudinal research on subjective aging, health, and longevity : Current evidence and new directions for research

    NARCIS (Netherlands)

    Westerhof, Gerben J.; Wurm, Susanne

    2015-01-01

    In this chapter, we carry out a narrative review of the longitudinal impact of subjective aging on health and survival. We have a specifi c focus on the different pathways which can explain the relation of subjective aging to health and survival. We focus on the three most common conceptualizations

  4. Payment of research participants: current practice and policies of Irish research ethics committees.

    LENUS (Irish Health Repository)

    Roche, Eric

    2013-09-01

    Payment of research participants helps to increase recruitment for research studies, but can pose ethical dilemmas. Research ethics committees (RECs) have a centrally important role in guiding this practice, but standardisation of the ethical approval process in Ireland is lacking.

  5. [Priorities for health policy and systems research focused on human resources in health].

    Science.gov (United States)

    Reveiz, Ludovic; Chapman, Evelina; Flórez, Carlos E Pinzón; Torres, Rubén

    2013-11-01

    Identify priorities for health policy and systems research related to human resources in Latin America and Caribbean countries. An online survey was designed based on a search in PubMed, Cochrane Library, and LILACS that contributed previously prioritized research questions. Respondents, mainly researchers and decision-makers, were identified through various sources. The first round, directed at researchers, aimed at refining and adding research questions and prioritizing questions that researchers regarded as relevant or very relevant. The second round was directed at researchers and decision-makers. A question was considered a priority when 50% (or more) of respondents described it as "relevant" or "very relevant." The first round included 20 questions on human resources and 33/66 researchers responded. Questions suggested by the researchers were added, resulting in 26 questions for the second round, which were sent to 121 researchers and decision-makers. Respondent representation by country was uniform in both rounds. In the second round, 14/26 (54%) questions were described as very relevant. Priority issues related to regulation of the market, integration of education and health care needs, and distribution of human resources. The response rate was 50% in the first round (33/66), and 34% in the second round (41/121). The results of this exercise provide a starting point for mobilization of resources for health policy and systems research. Identification of health systems research priorities is an effective and efficient strategy for reorienting political, financial, management, and social organization efforts for attaining universal health coverage.

  6. Experiments investigating the effects of the accelerating gap voltage pulse on the ion focused (IFR) high current electron recirculators

    International Nuclear Information System (INIS)

    Mazarakis, M.G.; Smith, D.L.; Poukey, J.W.; Wagner, J.S.; Bennett, L.F.; Olson, W.R.; Turman, B.N.; Prestwich, K.R.; Wells, J.

    1991-01-01

    The lifetime of the Ion Focusing Regime (IFR) channel following the pulsing of the post-accelerating gaps is critical for an open-ended, spiral recirculating electron linear accelerator. It dictates the number of allowable beam recirculations through the gap. In the case of a racetrack configuration, it is significant but not as critical, since the presence of the electron beam focuses the ions and lengthens the lifetime of the ion channel. It was established that pulsing the accelerating gap perturbs the IFR channel. However, for the parameters studied, the lifetime is long enough to allow at least four beam recirculations in a spiral device. In addition, cusp fields positioned upstream and downstream from the gap prevent it from perturbing the IFR channel. 4 refs., 5 figs., 1 tab

  7. Experiments investigating the effects of the accelerating gap voltage pulse on the ion focused (IFR) high current electron recirculators

    International Nuclear Information System (INIS)

    Mazarakis, M.G.; Smith, D.L.; Poukey, J.W.; Wagner, J.S.; Bennett, L.F.; Olson, W.R. Turnman, B.N.; Prestwich, K.R.; Wells, J.

    1991-01-01

    The lifetime of the Ion Focusing Regime (IFR) channel following the pulsing of the post-accelerating gaps is critical for an open-ended, spiral recirculating electron linear accelerator. It dictates the number of allowable beam recirculations through the gap. In the case of a racetrack configuration, its is significant but not as critical, since the presence of the electron beam focuses the ions and lengthens the lifetime of the ion channel. It was established that pulsing the accelerating gap perturbs the IFR channel. However, for the parameters studied, the lifetime is long enough to allow at least four beam recirculations in a spiral device. In addition, cusp fields positioned upstream and downstream from the gap prevent it from perturbing the IFR channel

  8. Diagnostic systems for the nuclear fusion and plasma research in the PF-24 plasma focus laboratory at the IFJ PAN

    Directory of Open Access Journals (Sweden)

    Marciniak Łukasz

    2016-12-01

    Full Text Available This paper presents a set of diagnostics dedicated to PF-24 - new medium size - plasma focus (PF device built and operated at the Institute of Nuclear Physics Polish Academy of Sciences (IFJ PAN. The PF-24 can operate at energy level up to 93 kJ and charging voltage up to 40 kV. Each condenser is connected with a specially designed spark gap with a very small jitter, which ensures a high effi ciency and a low current rise time. The working parameters of PF-24 generator make it a suitable tool for testing new detection systems to be used in fusion research. Four types of such detection systems are presented in this article: three diagnostic systems used to measure electric quantities (Rogowski coil, magnetic probe, capacitance probe, neutron counter based on beryllium activation, fast neutron pinhole camera based on small-area BCF-12 plastic scintillation detectors and high-speed four-frame soft X-ray camera with microchannel plate.

  9. In vitro psoriasis models with focus on reconstructed skin models as promising tools in psoriasis research.

    Science.gov (United States)

    Desmet, Eline; Ramadhas, Anesh; Lambert, Jo; Van Gele, Mireille

    2017-06-01

    Psoriasis is a complex chronic immune-mediated inflammatory cutaneous disease associated with the development of inflammatory plaques on the skin. Studies proved that the disease results from a deregulated interplay between skin keratinocytes, immune cells and the environment leading to a persisting inflammatory process modulated by pro-inflammatory cytokines and activation of T cells. However, a major hindrance to study the pathogenesis of psoriasis more in depth and subsequent development of novel therapies is the lack of suitable pre-clinical models mimicking the complex phenotype of this skin disorder. Recent advances in and optimization of three-dimensional skin equivalent models have made them attractive and promising alternatives to the simplistic monolayer cultures, immunological different in vivo models and scarce ex vivo skin explants. Moreover, human skin equivalents are increasing in complexity level to match human biology as closely as possible. Here, we critically review the different types of three-dimensional skin models of psoriasis with relevance to their application potential and advantages over other models. This will guide researchers in choosing the most suitable psoriasis skin model for therapeutic drug testing (including gene therapy via siRNA molecules), or to examine biological features contributing to the pathology of psoriasis. However, the addition of T cells (as recently applied to a de-epidermized dermis-based psoriatic skin model) or other immune cells would make them even more attractive models and broaden their application potential. Eventually, the ultimate goal would be to substitute animal models by three-dimensional psoriatic skin models in the pre-clinical phases of anti-psoriasis candidate drugs. Impact statement The continuous development of novel in vitro models mimicking the psoriasis phenotype is important in the field of psoriasis research, as currently no model exists that completely matches the in vivo psoriasis

  10. Research as an event: a novel approach to promote patient-focused drug development

    Directory of Open Access Journals (Sweden)

    Tsai JH

    2018-05-01

    Full Text Available Jui-Hua Tsai, Ellen Janssen, John FP Bridges Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA Abstract: Patient groups are increasingly engaging in research to understand patients’ preferences and incorporate their perspectives into drug development and regulation. Several models of patient engagement have emerged, but there is little guidance on how to partner with patient groups to engage the disease community. Our group has been using an approach to engage patient groups that we call research as an event. Research as an event is a method for researchers to use a community-centered event to engage patients in their own environment at modest incremental cost. It is a pragmatic solution to address the challenges of engaging patients in research to minimize patients’ frustration, decrease the time burden, and limit the overall cost. The community, the event, and the research are the three components that constitute the research as an event framework. The community represents a disease-specific community. The event is a meeting of common interest for patients and other stakeholders, such as a patient advocacy conference. The research describes activities in engaging the community for the purpose of research. Research as an event follows a six-step approach. A case study is used to demonstrate the six steps followed by recommendations for future implementation. Keywords: patients’ perspectives, decision making, drug approval, patient engagement, patient organization, patients’ preference

  11. Payment of research participants: current practice and policies of Irish research ethics committees.

    Science.gov (United States)

    Roche, Eric; King, Romaine; Mohan, Helen M; Gavin, Blanaid; McNicholas, Fiona

    2013-09-01

    Payment of research participants helps to increase recruitment for research studies, but can pose ethical dilemmas. Research ethics committees (RECs) have a centrally important role in guiding this practice, but standardisation of the ethical approval process in Ireland is lacking. Our aim was to examine REC policies, experiences and concerns with respect to the payment of participants in research projects in Ireland. Postal survey of all RECs in Ireland. Response rate was 62.5% (n=50). 80% of RECs reported not to have any established policy on the payment of research subjects while 20% had refused ethics approval to studies because the investigators proposed to pay research participants. The most commonly cited concerns were the potential for inducement and undermining of voluntary consent. There is considerable variability among RECs on the payment of research participants and a lack of clear consensus guidelines on the subject. The development of standardised guidelines on the payment of research subjects may enhance recruitment of research participants.

  12. Focus Group Research on the Implications of Adopting the Unified English Braille Code

    Science.gov (United States)

    Wetzel, Robin; Knowlton, Marie

    2006-01-01

    Five focus groups explored concerns about adopting the Unified English Braille Code. The consensus was that while the proposed changes to the literary braille code would be minor, those to the mathematics braille code would be much more extensive. The participants emphasized that "any code that reduces the number of individuals who can access…

  13. Guidance on Performing Focused Ethnographies with an Emphasis on Healthcare Research

    Science.gov (United States)

    Higginbottom, Gina M. A.; Pillay, Jennifer J.; Boadu, Nana Y.

    2013-01-01

    Focused ethnographies can have meaningful and useful application in primary care, community, or hospital healthcare practice, and are often used to determine ways to improve care and care processes. They can be pragmatic and efficient ways to capture data on a specific topic of importance to individual clinicians or clinical specialties. While…

  14. A New Method for Research on the Center-Focus Problem of Differential Systems

    OpenAIRE

    Zhou, Zhengxin

    2014-01-01

    We will introduce Mironenko’s method to discuss the Poincaré center-focus problem, and compare the methods of Lyapunov and Mironenko. We apply the Mironenko method to discuss the qualitative behavior of solutions of some planar polynomial differential systems and derive the sufficient conditions for a critical point to be a center.

  15. Focus on Basics: Connecting Research and Practice: Workplace Education, Volume 7, Issue B

    Science.gov (United States)

    National Center for the Study of Adult Learning and Literacy, 2004

    2004-01-01

    This issue focuses on workplace education and includes the following articles: "After the Grant Is Over" (Connie Nelson); "Around to Stay" (Shirley Penn and Mary Zorn); "A Conversation with FOB: What Benefits Does Workplace Ed Offer the Provider?"; "Reading Work" (Tracy Defoe and Sue Folinsbee); "Much More than ABE" (Don Block and Lori…

  16. COURSE : a new industry led consortium to focus and accelerate energy resources research at Alberta University

    Energy Technology Data Exchange (ETDEWEB)

    Rodgers, R.J. [Imperial Oil Resources Ltd., Calgary, AB (Canada); Bailey, R. [Alberta Oil Sands Technology and Research Authority, Edmonton, AB (Canada); Kirk, M. [Calgary Univ., AB (Canada); Luhning, R.W. [Petroleum Recovery Inst., Calgary, AB (Canada); Kratochvil, R. [Alberta Univ., Edmonton, AB (Canada)

    2000-06-01

    This paper described a new initiative entitled COURSE (Coordination of University Research for Synergy and Effectiveness) which has been created through the collaboration of the energy industry, universities and the Alberta government to promote research in the field of energy resources. Calls for research proposals went out in June 1999 and January 2000. The selected projects will be funded by the Alberta Ministry of Innovation and Science through the Alberta Oil Sands Technology and Research Authority (AOSTRA). The major objectives of COURSE are to increase and align fundamental breakthrough university research with the industry needs, and to provide results that exceed what would be achieved by one university alone. An agreement has been reached whereby the universities own the technology and are the exclusive license agents of the research.

  17. Perspectives on Research Participation and Facilitation Among Dialysis Patients, Clinic Personnel, and Medical Providers: A Focus Group Study.

    Science.gov (United States)

    Flythe, Jennifer E; Narendra, Julia H; Dorough, Adeline; Oberlander, Jonathan; Ordish, Antoinette; Wilkie, Caroline; Dember, Laura M

    2017-12-19

    Most prospective studies involving individuals receiving maintenance dialysis have been small, and many have had poor clinical translatability. Research relevance can be enhanced through stakeholder engagement. However, little is known about dialysis clinic stakeholders' perceptions of research participation and facilitation. The objective of this study was to characterize the perspectives of dialysis clinic stakeholders (patients, clinic personnel, and medical providers) on: (1) research participation by patients and (2) research facilitation by clinic personnel and medical providers. We also sought to elucidate stakeholder preferences for research communication. Qualitative study. 7 focus groups (59 participants: 8 clinic managers, 14 nurses/patient care technicians, 8 social workers/dietitians, 11 nephrologists/advanced practice providers, and 18 patients/care partners) from 7 North Carolina dialysis clinics. Clinics and participants were purposively sampled. Focus groups were recorded and transcribed. Thematic analysis. We identified 11 themes that captured barriers to and facilitators of research participation by patients and research facilitation by clinic personnel and medical providers. We collapsed these themes into 4 categories to create an organizational framework for considering stakeholder (narrow research understanding, competing personal priorities, and low patient literacy and education levels), relationship (trust, buy-in, and altruistic motivations), research design (convenience, follow-up, and patient incentives), and dialysis clinic (professional demands, teamwork, and communication) aspects that may affect stakeholder interest in participating in or facilitating research. These themes appear to shape the degree of research readiness of a dialysis clinic environment. Participants preferred short research communications delivered in multiple formats. Potential selection bias and inclusion of English-speaking participants only. Our findings

  18. Overview on neutron beam industry-focused strategic research in Malaysia

    International Nuclear Information System (INIS)

    Abdul Aziz Mohamed; Razali Kassim; Abdul Jalil Abdul Hamid; Azali Muhammad; Muhammad Rawi Mohd Zain; Azhar Azmi

    2002-01-01

    The TRIGA MARK II research reactor (RTP) at the Malaysian Institute for Nuclear Technology Research (MINT) was commissioned in July 1982. RTP is a 1 MW steady state reactor which being used for reactor training and research related to neutron. Since then various works have been performed to utilise the neutrons produced from this steady state reactor. Projects undertaken are the development and utilization of the neutron radiography (myNR) and small angle neutron scattering (mySANS) facilities. This poster highlights the recent status the above neutron beam facilities and their application in materials science and technology research and education. (Author)

  19. 76 FR 38399 - Assessing the Current Research, Policy, and Practice Environment in Public Health Genomics

    Science.gov (United States)

    2011-06-30

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention [Docket Number CDC-2011-0008] Assessing the Current Research, Policy, and Practice Environment in Public Health... information helpful to assess the current research, policy, and practice environment in public health genomics...

  20. Book Review: Current Issues in International Human Resource Management and Strategy Research

    DEFF Research Database (Denmark)

    Gretzinger, Susanne

    2009-01-01

    The article reviews the book "Current Issues in International Human Resource Management and Strategy Research," edited by Marion Festing and Susanne Royer.......The article reviews the book "Current Issues in International Human Resource Management and Strategy Research," edited by Marion Festing and Susanne Royer....

  1. Annotated bibliography: Marine geologic hazards of the Hawaiian Islands with special focus on submarine slides and turbidity currents

    Energy Technology Data Exchange (ETDEWEB)

    Normark, W.R.; Herring, H.H.

    1993-10-01

    This annotated bibliography was compiled to highlight the submarine geology of the Hawaiian Islands and identify known and potential marine geologic hazards with special emphasis on turbidity currents, submarine slides and tsunamis. Some references are included that are not specific to Hawaii but are needed to understand the geologic processes that can affect the integrity of submarine cables and other man-made structures. Entries specific to the Hawaiian Island area are shown in bold type.

  2. Reactor safety research program. A description of current and planned reactor safety research sponsored by the Nuclear Regulatory Commission's Division of Reactor Safety Research

    International Nuclear Information System (INIS)

    1975-06-01

    The reactor safety research program, sponsored by the Nuclear Regulatory Commission's Division of Reactor Safety Research, is described in terms of its program objectives, current status, and future plans. Elements of safety research work applicable to water reactors, fast reactors, and gas cooled reactors are presented together with brief descriptions of current and planned test facilities. (U.S.)

  3. Peer Mentoring for Undergraduates in a Research-Focused Diversity Initiative

    Science.gov (United States)

    Keller, Thomas E.; Logan, Kay; Lindwall, Jennifer; Beals, Caitlyn

    2017-01-01

    To provide multi-dimensional support for undergraduates from traditionally underrepresented backgrounds who aspire to careers in research, the BUILD EXITO project, part of a major NIH-funded diversity initiative, matches each scholar with three mentors: peer mentor (advanced student), career mentor (faculty adviser), and research mentor (research…

  4. Response to 'Comment on 'Pinch current limitation effect in plasma focus'' [Appl. Phys. Lett. 94, 076101 (2009)

    International Nuclear Information System (INIS)

    Lee, S.; Saw, S. H.

    2009-01-01

    The main point of the comment [Appl. Phys. Lett. 94, 076101 (2009)] is that Eq. (2) and consequentially Eq. (3) of the commented paper [Appl. Phys. Lett. 92, 021503 (2008)] require correction. The alternative equation suggested in the comment is derived using Kirchhoff's voltage rule. The comment consider only the energy distribution in the inductive components and the resultant equation confirms a progressive lowering of the I pinch /I peak ratio as the static inductance L 0 is reduced, lowering from 0.87 to 0.31 as L 0 is reduced from 100 to 5 nH according to the revised formula corresponding to Eq. (3), compared to 0.63-0.25 according to Eq. (3). This progressive lowering of the ratio I pinch /I peak due to the inductive energy distribution is one of two factors responsible for the pinch current limitation. The other factor is the progressive reduction in the L-C interaction time compared to the current dip duration denoted by δ cap in Eq. (2). The comment does not deal with δ cap at all; hence, its conclusion based on inductive energy distribution only is not useful, since in the low L 0 region when pinch current limitation begins to manifest, δ cap becomes more and more the dominant factor. In any case, the results of the paper do not depend on Eqs. (2) and (3), which are used in the paper only for illustrative purposes

  5. Current state in the research on electronic monitoring systems for the security and flow of objects and individuals

    Directory of Open Access Journals (Sweden)

    Man Dietrich Marcela

    2017-01-01

    Full Text Available This paper sets forth the current state of security systems in prisons from Romania and around the world, particularly aiming electronic systems of monitoring the flow of people, materials control and perimeter security, focusing on the research results concluded by motion detection tests and devices. The currently used systems were observed in order to put an analysis of the methodology together and implement and perfect these systems in protected areas. The protection of citizens must be performed to the extent that is allowed by the legislation.

  6. Geography should not be destiny: focusing HIV/AIDS implementation research and programs on microepidemics in US neighborhoods.

    Science.gov (United States)

    Nunn, Amy; Yolken, Annajane; Cutler, Blayne; Trooskin, Stacey; Wilson, Phill; Little, Susan; Mayer, Kenneth

    2014-05-01

    African Americans and Hispanics are disproportionately affected by the HIV/AIDS epidemic. Within the most heavily affected cities, a few neighborhoods account for a large share of new HIV infections. Addressing racial and economic disparities in HIV infection requires an implementation program and research agenda that assess the impact of HIV prevention interventions focused on increasing HIV testing, treatment, and retention in care in the most heavily affected neighborhoods in urban areas of the United States. Neighborhood-based implementation research should evaluate programs that focus on community mobilization, media campaigns, routine testing, linkage to and retention in care, and block-by-block outreach strategies.

  7. Focusing ethnography

    DEFF Research Database (Denmark)

    Woermann, Niklas

    2018-01-01

    underpinnings of focusing ethnographic research by comparing different schools of thought and suggesting a practice theory-based approach. It argues that many research projects are focused but do not reflect on the process of focusing, describes how to identify focal settings or practices, and introduces......Building theory with ethnography and filmic research increasingly requires focussing on key practices or settings, instead of painting a broad panorama of a culture. But few authors discuss why and how to focus. This article provides a systematic discussion of the theoretical and methodological...

  8. Researches focused on structure of aluminium alloys processed by rapid solidification, used in automotive industry

    International Nuclear Information System (INIS)

    Sfat, C.; Vasile, T.; Vasilescu, M.

    2001-01-01

    The paper present some new results focused on an aluminium high temperature alloy, obtained by 'melt spinning method'. alloy composition, processing conditions, resulted structures and the influence between them are presented. There are studied the two zone structures of the alloy and the relation between processing conditions and the characteristics of the zones, with implications on mechanical behavior in real conditions. The final conclusion show that is possible to control the structure in order to improve material behavior. (author)

  9. Contextualize that sort focus in the work and research training of the pedagogical career

    Directory of Open Access Journals (Sweden)

    David Ruiz-Ducasse

    2017-04-01

    Full Text Available This paper have purpose of perfecting continuous for learning and teaching process in the pedagogy careers, in this case, from a sort focus perspective. From development didactic of the labor investigative practice, he suggests idea about of the woman role. This work will let a change in the way proceeding of the professors’ future, to using the possibility that offer of the subject, for to guarantee a tally behaved and educate formation, which will let a first educate labor.

  10. Focus Groups Help To Focus the Marketing Strategy.

    Science.gov (United States)

    Ashar, Hanna; Lane, Maureen

    1996-01-01

    A university-based degree completion program for adults conducted focus group research to refine market positioning and promotion. Focus groups averaged five current students and recent graduates who reflected, demographically, the current student population. Results gave insight into reasons for selecting the university, aspects of the program…

  11. FOCUS-GROUP AND ITS IMPACT IN THE QUESTIONNAIRE OF MARKETING RESEARCH ON THE ROMANIAN CAR MARKET

    Directory of Open Access Journals (Sweden)

    MANEA Constantin

    2010-12-01

    Full Text Available Designing a questionnaire is the most profound activity which makes an impact on a research in marketing. The investigation instrument finally determines the quality of this type of research. Never will a market research be able to exceed its questionnaire in point of quality. The present contribution succinctly itemizes a research project for the Romanian car market, emphasizing the importance of focus group, and appends, at the end, the concrete result, applied to the Romanian car market. The first part describes the hypotheses and sets out the objectives of the research, focusing on the market leader, i.e. Automobile Dacia Renault. The second section describes the practical process of designing the questionnaire, with a special stress laid on the impact of focus-group in the final version. The synthesis of focus group is materialized through a number of final remarks on the manner of concretely writing the questionnaire, which was put to practical use on the Romanian car market.

  12. Eastern forested watersheds: the OHER/ERD research focus at Oak Ridge National Laboratory

    International Nuclear Information System (INIS)

    Reichle, D.E.

    1985-01-01

    An overview of the environmental research programs conducted at Oak Ridge National Laboratory (ORNL) under the auspices of the DOE Office of Health and Environmental Research (OHER) is presented. The research is focussed on the pathways of movement of chemicals from the atmosphere, through terrestrial environments, to receiving water bodies and the effects of these chemicals and other anthropogenic activities on biological systems and biogeochemical processes exposed during transport. Three fundamental levels of the environmental hierarchy are encompassed: process, system, and landscape. 5 refs

  13. Topical and Geographical Focus of Chinese Oceanographic Research - A Study of Trends in Publication

    National Research Council Canada - National Science Library

    Chu, Peter C; Li, Rongfeng

    2008-01-01

    .... Funds increase rapidly for education and scientific research. From 1993 to 2006, enrollment of full time students in universities and colleges grew from 924,000 to 5,400,000, total number of students (including part-time...

  14. Building Capacity in Community-Based Participatory Research Partnerships Through a Focus on Process and Multiculturalism.

    Science.gov (United States)

    Corbie-Smith, Giselle; Bryant, Angela R; Walker, Deborah J; Blumenthal, Connie; Council, Barbara; Courtney, Dana; Adimora, Ada

    2015-01-01

    In health research, investigators and funders are emphasizing the importance of collaboration between communities and academic institutions to achieve health equity. Although the principles underlying community-academic partnered research have been well-articulated, the processes by which partnerships integrate these principles when working across cultural differences are not as well described. We present how Project GRACE (Growing, Reaching, Advocating for Change and Empowerment) integrated participatory research principles with the process of building individual and partnership capacity. We worked with Vigorous Interventions In Ongoing Natural Settings (VISIONS) Inc., a process consultant and training organization, to develop a capacity building model. We present the conceptual framework and multicultural process of change (MPOC) that was used to build individual and partnership capacity to address health disparities. The process and capacity building model provides a common language, approach, and toolset to understand differences and the dynamics of inequity. These tools can be used by other partnerships in the conduct of research to achieve health equity.

  15. The need for a behavioural science focus in research on mental health and mental disorders

    NARCIS (Netherlands)

    Wittchen, H.U.; Knappe, S.; Andersson, G.; Araya, R.; Banos Rivera, R.M.; Barkham, M.; Bech, P.; Beckers, T.; Berger, T.; Berking, M.; Berrocal, C.; Botella, C.; Carlbring, P.; Chouinard, G.; Colom, F.; Csillag, C.; Cuijpers, P.; David, D.; Emmelkamp, P.M.G; Essau, C.A.; Fava, G.A.; Goschke, T.; Hermans, D.; Hofmann, S.G.; Lutz, W.; Muris, P.; Ollendick, T.H.; Raes, F.; Rief, W.; Riper, H.; Tossani, E.; van der Oord, S.; Vervliet, B.; Haro, J.M.; Schumann, G.

    2014-01-01

    Psychology as a science offers an enormous diversity of theories, principles, and methodological approaches to understand mental health, abnormal functions and behaviours and mental disorders. A selected overview of the scope, current topics as well as strength and gaps in Psychological Science may

  16. In the past two decades, research interest has focused on the eddy ...

    African Journals Online (AJOL)

    spamer

    process, and stretch hundreds of kilometres offshore. A typical core velocity is 50 .... the average current from 8 to 72 m deep was barotropic. A criticism of a synthesis ..... the Agulhas Bank, a shallow plateau some 105 km2 inshore of the 300-m ...

  17. Human Research and Engineering Directorate, Major Laboratory Programs: Current Thrust Areas and Recent Research

    Science.gov (United States)

    2010-09-01

    response equipment. After the hardware and software infrastructure is complete, the focus will shift to creating soundscapes over headphones and...Background sounds will emulate a range of conditions from quiet deserts to busy urban streets. Accurate portrayals of military soundscapes and listening

  18. Focus on CSIR research in pollution waste: Water resource governance systems

    CSIR Research Space (South Africa)

    Rascher, J

    2007-08-01

    Full Text Available series of high level research programmes for ecosystem governance. These are illustrated in the fi gure below. The size of the individual circles indicates the priority attributed to the specifi c research theme by the symposium participants... Governance Socio-econ Define Economy of scale Context application Generic strategies/methods Link to democracy 3 Science Communication, learning & knowledge sharing 4 Integration of formal & traditional systems Hydrological boundaries Value...

  19. Should We Formulate an Incentivized Model Facilitating Kidney Donation from Living Donors? A Focus on Turkey's Current System.

    Science.gov (United States)

    Avci, Ercan

    2018-04-23

    Kidney transplantation is a lifesaving medical treatment. However, very high demand for kidneys with low kidney donation causes a black market that exploits patients' desperation and donors' vulnerability. The current kidney donation programs fail to produce promising results to avoid illegal and unethical kidney trafficking and commercialism. Even though the primary goal of kidney donation is to increase the number of deceased organ donations, in some countries, like Turkey, due to religious or cultural concerns, it is impossible to supply adequate deceased kidney donations. In this view, the aim of this paper is to examine kidney trafficking in the scope of Turkey's current organ donation system and propose a new model, named the Incentivized Kidney Donation Model (IKDM), to increase kidney donation from living donors. The model encompasses the following benefits offered to kidney donors; lifetime health insurance, exemptions from copayments/contribution shares, priority when receiving an organ, priority when finding a job, income tax exemptions for salaried employees, and free or discounted public utilities. This normative model has the potential to promote donors' altruistic acts as well as the solidarity and loyalty among members of a society without violating ethical values and internationally accepted principles. © 2018 John Wiley & Sons Ltd.

  20. Current cancer research. Reports from the German Cancer Research Center 1998

    International Nuclear Information System (INIS)

    1998-01-01

    Topics from the Contents: The Fight against Cancer in Germany - A Critical Review. Conditions and Structures in Research. Familial Breast Cancer - A Critical Assessment. Research without Animal Experiments. Cancer Prevention. New Approaches for Tumor Therapy. Genes, Chromosomes and Cancer. Therapy of Brain Tumors with Laser Neurosurgery. The Genome Project. (orig.) [de