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Sample records for current rbca criteria

  1. Restless Legs Syndrome with Current Diagnostic Criteria

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    Meral Bilgilisoy Filiz

    2015-08-01

    Full Text Available Restless legs syndrome (RLS, also known as Willis-Ekbom disease, is a chronic movement disorder, characterized by an urge to move legs usually accompanied by uncomfortable sensations and sleep disorders. The prevalence of the syndrome ranges from 1% to 15% in the general population, and about 2% during childhood. RLS is the most common movement disorder in pregnancy. However RLS still remains underdiagnosed probably due to lack of accurate information about the disease. Family history is positive in 50-70% of the primary RLS patients. The secondary form of the syndrome is associated with iron deficiency, renal failure, pregnancy, diabetes mellitus and many rheumatologic disorders. Secondary forms generally manifest at older ages and have a rapid progression with a poorer prognosis. The pathophysiology of RLS is focused on the dopaminergic system, reduced central nervous system iron levels and genetic linkages. Diagnosis is based on clinical features and the diagnostic criteria suggested by International RLS Study Group. Secondary causes must be carefully investigated before the treatment. In mild forms of the disease non-pharmacologic therapies might be useful, while in moderate or severe forms of the disease generally pharmacologic therapies such as dopamine agonists, anticonvulsants, opioids and benzodiazepines are required. (Turkish Journal of Osteoporosis 2015;21: 87-95

  2. RbCa2Nb3O10 from X-ray powder data

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    Zhen-Hua Liang; Kai-Bin Tang; Qian-Wang Chen; Hua-Gui Zheng

    2009-01-01

    Rubidium dicalcium triniobate(V), RbCa2Nb3O10, has been synthesized by solid-state reaction and its crystal structure refined from X-ray powder diffraction data using Rietveld analysis. The compound is a three-layer perovskite Dion–Jacobson phase with the perovskite-like slabs derived by termination of the three-dimensional CaNbO3 perovskite structure along the ab plane. The rubidium ions (4/mmm symmetry) are located in the interstitial space.

  3. Pathology and sensitivity of current clinical criteria in corticobasal syndrome.

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    Ouchi, Haruka; Toyoshima, Yasuko; Tada, Mari; Oyake, Mutsuo; Aida, Izumi; Tomita, Itsuro; Satoh, Akira; Tsujihata, Mitsuhiro; Takahashi, Hitoshi; Nishizawa, Masatoyo; Shimohata, Takayoshi

    2014-02-01

    The aim of this study was to investigate corticobasal syndrome with respect to underlying pathologies, the ability of current clinical criteria to detect early stages of disease, and symptoms and signs predicting background pathologies. We retrospectively analyzed the clinicopathological findings from patients with corticobasal syndrome. We also analyzed whether those findings fulfilled the diagnostic criteria for corticobasal degeneration (CBD). Finally, we investigated characteristic clinical features that are specific to each background pathology. Of 10 consecutive autopsied patients who had corticobasal syndrome (mean age ± standard deviation, 67.9 ± 9.3 years; male:female ratio, 6:4), three had corticobasal degeneration pathology, three had progressive supranuclear palsy, three had Alzheimer's disease, and one had atypical four-repeat tauopathy. Nine patients fulfilled Mayo criteria, and all 10 patients fulfilled modified Cambridge criteria at the later stage, but only two patients fulfilled either clinical criteria within 2 years of disease onset. Five patients fulfilled the clinical criteria for possible CBD (p-CBD), and one patient fulfilled the clinical research criteria for probable sporadic CBD (cr-CBD) at the later stage. Only two patients fulfilled the criteria for either p-CBD or cr-CBD within 2 years of disease onset. Although we could not find any predictive characteristic clinical features that were specific to CBD pathology, only patients with progressive supranuclear palsy developed apraxia of eyelid opening and cerebellar ataxia. Myoclonus and memory impairment, especially if they appear at an early stage of the disease, may predict Alzheimer's disease pathology. Sensitivity of the available clinical criteria for corticobasal syndrome was poor within 2 years of disease onset.

  4. Evidence for current diagnostic criteria of diabetes mellitus

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    Ritesh; Kumar[1; Lakshmana; Perumal; Nandhini[1; Sadishkumar; Kamalanathan[1; Jayaprakash; Sahoo[1; Muthupillai; Vivekanadan[1

    2016-01-01

    Diabetes mellitus is a non-communicable metabolic derangement afflicting several millions of individuals globally. It is associated with several micro and macrovascular complications and is also a leading cause of mortality. The unresolved issue is that of definition of the diagnostic threshold for diabetes. The World Health Organization and the American Diabetes Association (ADA) have laid down several diagnostic criteria for diagnosing diabetes and prediabetes based on the accumulating body of evidence.This review has attempted to analyse the scientific evidence supporting the justification of these differing criteria. The evidence for diagnosing diabetes is strong, and there is a concordance between the two professional bodies.The controversy arises when describing the normal lower limit of fasting plasma glucose (FPG) with little evidence favouring the reduction of the FPG by the ADA. Several studies have also shown the development of complications specific for diabetes in patients with prediabetes as defined by the current criteria though there is a significant overlap of such prevalence in individuals with normoglycemia. Large multinational longitudinal prospective studies involving subjects without diabetes and retinopathy at baseline will ideally help identify the threshold of glycemic measurements for future development of diabetes and its complications.

  5. Evidence for current diagnostic criteria of diabetes mellitus

    Science.gov (United States)

    Kumar, Ritesh; Nandhini, Lakshmana Perumal; Kamalanathan, Sadishkumar; Sahoo, Jayaprakash; Vivekanadan, Muthupillai

    2016-01-01

    Diabetes mellitus is a non-communicable metabolic derangement afflicting several millions of individuals globally. It is associated with several micro and macrovascular complications and is also a leading cause of mortality. The unresolved issue is that of definition of the diagnostic threshold for diabetes. The World Health Organization and the American Diabetes Association (ADA) have laid down several diagnostic criteria for diagnosing diabetes and prediabetes based on the accumulating body of evidence.This review has attempted to analyse the scientific evidence supporting the justification of these differing criteria. The evidence for diagnosing diabetes is strong, and there is a concordance between the two professional bodies. The controversy arises when describing the normal lower limit of fasting plasma glucose (FPG) with little evidence favouring the reduction of the FPG by the ADA. Several studies have also shown the development of complications specific for diabetes in patients with prediabetes as defined by the current criteria though there is a significant overlap of such prevalence in individuals with normoglycemia. Large multinational longitudinal prospective studies involving subjects without diabetes and retinopathy at baseline will ideally help identify the threshold of glycemic measurements for future development of diabetes and its complications. PMID:27660696

  6. [Neurodegenerative disorders: review of current classification and diagnostic neuropathological criteria].

    Science.gov (United States)

    Matej, R; Rusina, R

    2012-04-01

    Neurodegenerative disorders are progressive diseases characterized by loss of specific neuronal populations followed by a clinical picture of a different neurodegenerative entity. Current classification of these diseases respects the names of the main pathophysiological processes involved in the groups of disorders. This is the reason why key proteins which represent neuropathological and biochemical hallmarks of diseases are found in their names. Neuropathological diagnosis is a synthesis of neurohistological changes in the brain and spinal cord and identification of pathological proteinaceous aggregates in neurons and/or glial cells. These inclusions are predominant diagnostic micromorphological and biochemical markers of disease. In the text, there is a brief summary of current knowledge about pathophysiology of neurodegenerations and diagnostic criteria for the most frequent entities.

  7. Assessment of current criteria for dynamic stability of container vessels

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    Stanca, C.; Ancuta, C.; Acomi, N.; Andrei, C.

    2016-08-01

    Container vessels sailing through heavy weather are exposed to a significant variation of stability due to specific shape of the hull combined with the action of the waves. Even if the weather forecast is transmitted to vessels, the way of acting it is a matter of officers’ experience. The Maritime Safety Committee, under the International Maritime Organization, has approved the Guidance to the master for avoiding dangerous situations in adverse weather and sea conditions. Adverse weather conditions include wind induced waves or heavy swell. The development of dangerous phenomena such as surf-riding and broaching to, syncronious and parametric rollings is a result of a these adverse conditions which has to be encountered by the vessels. Understanding the dynamic stability of the vessel in the waves and ship's behaviour based on mathematical and physical rules is a difficult task, any effort in order to assess these components are salutary. To avoid excessive acceleration and forces which can damage the hull of the vessel, lashing and integrity of containers, course and speed may need to be changed for the vessel's motion in heavy seas. Specific software have been developed as aids for evaluating the response of the vessel in heavy seas according to parameters variations. The paper aims at assessing of current criteria for dynamic stability of a container vessel model ship in order to determine the ways for avoiding dangerous conditions. The results should be regarded as a supporting tool during the decision making process.

  8. Research Diagnostic criteria for Temporomandibular Disorders: current status & future relevance.

    Science.gov (United States)

    Dworkin, S F

    2010-10-01

    The Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD), published in 1992, was based on international expert recommendations and available empirical data. The major rationale was to offer a putative diagnostic and classification system whose reliability, validity and clinical usefulness for TMD diagnosis and classification could be scientifically evaluated and then revised using an evidence-based model for successive iterations. The present journal issue attests to the accomplishment of that major objective: the RDC/TMD has been translated into 18 languages and used very extensively in international research. One important component of that research has been to yield reliable and valid data resulting in an evidence-based revision of the RDC/TMD now available for continuing research and clinical application. The present article offers recommendations and speculations regarding how the RDC/TMD may continue to serve the function of guiding future research and, most importantly, serve as an evidence-based diagnostic and classification system to aid in the rational choice of clinical care for TMD sufferers around the world.

  9. Use of corrective action based on risk - RBCA - in the cases of soil and underground water contamination by gasoline in Brazil; Uso da acao corretiva baseada no risco - RBCA - nos casos de contaminacao de solos e aguas subterraneas por gasolina no Brasil

    Energy Technology Data Exchange (ETDEWEB)

    Finotti, Alexandra Rodrigues; Corseuil, Henry Xavier [Santa Catarina Univ., Florianopolis, SC (Brazil). Dept. de Engenharia Sanitaria e Ambiental]. E-mail: corseuil@ens.ufsc.br

    1997-07-01

    This work search evaluate the behaviour of a model used for risk based corrective action for selection of levels in presence of gasoline with ethanol mixtures. A study on mathematical models used as its source and behaviour during simulations for to evaluate the utilization of RBCA for gasoline and ethanol contamination is described.

  10. 40 CFR 93.114 - Criteria and procedures: Currently conforming transportation plan and TIP.

    Science.gov (United States)

    2010-07-01

    ... conforming transportation plan and TIP. 93.114 Section 93.114 Protection of Environment ENVIRONMENTAL....114 Criteria and procedures: Currently conforming transportation plan and TIP. There must be a currently conforming transportation plan and currently conforming TIP at the time of project approval, or...

  11. Lung scintigraphy in the diagnosis of pulmonary embolism: current methods and interpretation criteria in clinical practice.

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    Skarlovnik, Ajda; Hrastnik, Damjana; Fettich, Jure; Grmek, Marko

    2014-06-01

    In current clinical practice lung scintigraphy is mainly used to exclude pulmonary embolism (PE). Modified diagnostic criteria for planar lung scintigraphy are considered, as newer scitigraphic methods, especially single photon emission computed tomography (SPECT) are becoming more popular. Data of 98 outpatients who underwent planar ventilation/perfusion (V/Q) scintigraphy and 49 outpatients who underwent V/Q SPECT from the emergency department (ED) were retrospectively collected. Planar V/Q images were interpreted according to 0.5 segment mismatch criteria and revised PIOPED II criteria and perfusion scans according to PISA-PED criteria. V/Q SPECT images were interpreted according to the criteria suggested in EANM guidelines. Final diagnosis of PE was based on the clinical decision of an attending physician and evaluation of a 12 months follow-up period. Using 0.5 segment mismatch criteria and revised PIOPED II, planar V/Q scans were diagnostic in 93% and 84% of cases, respectively. Among the diagnostic planar scans readings specificity for 0.5 segment mismatch criteria was 98%, and 99% for revised PIOPED II criteria. V/Q SPECT showed a sensitivity of 100% and a specificity of 98%, without any non-diagnostic cases. In patients with low pretest probability for PE, planar V/Q scans assessed by 0.5 segment mismatch criteria were diagnostic in 92%, and in 85% using revised PIOPED II criteria, while perfusion scintigraphy without ventilation scans was diagnostic in 80%. Lung scintigraphy yielded diagnostically definitive results and is reliable in ruling out PE in patients from ED. V/Q SPECT has excellent specificity and sensitivity without any non-diagnostic results. Percentage of non-diagnostic results in planar lung scintigraphy is considerably smaller when 0.5 segment mismatch criteria instead of revised PIOPED II criteria are used. Diagnostic value of perfusion scintigraphy according to PISA-PED criteria is inferior to combined V/Q scintigraphy; the difference is

  12. Evaluating validity of current criteria for judgment passing ER rotation among internee medical students

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    Hooman Hoseinnejad

    2017-08-01

    Conclusions: According to association between successfully completions of training in emergency medicine and self-assessment questionnaire, it seems current criteria for judgment passing emergency medicine rotation is valid as well as we recommended using self-assessment for evaluating validity of such testes.

  13. Clinicians' perspective of the current diagnostic criteria for myofascial pain syndrome.

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    Grosman-Rimon, Liza; Clarke, Hance; Chan, Aaron K; Mills, Patricia Branco; Rathbone, Alasdair Timothy Llewelyn; Kumbhare, Dinesh

    2017-01-01

    Myofascial pain syndrome (MPS) is one of the most common chronic musculoskeletal pain disorders. However, MPS is often under-diagnosed. The purpose of this study was to characterize practicing clinicians' perspectives of the current diagnostic criteria for MPS. A cross-sectional study design was used with a self-administered questionnaire. The questionnaire evaluated clinicians' perspective of the current diagnostic criteria for MPS. The sample population (n= 119) consisted of 40% family physicians, 31% physical medicine (PM) and rehabilitation specialists, 11% rheumatologists, 10% emergency room (ER) physicians, and 8% anesthesiologists specializing in chronic pain. Our findings demonstrated that participating clinicians agree that ``point tenderness'' and ``pain reproduction'' are criteria for MPS. In contrast, the clinicians do not consider ``autonomic symptoms'' as an important criterion for MPS. The anesthesiologists view ``restricted range of motion'' as a criterion for MPS more than the other groups, and they tend to consider ``referred pain'' and ``pain reproduction'' as criteria. Physical medicine and rehabilitation specialists and anesthesiologists tend to view ``local twitch response'' more as a criterion for MPS compared with the other groups. Most groups of clinicians consider ``weakness without atrophy'' as an important MPS criterion except for family physicians. It is important to note that ``poor sleep'', ``daytime fatigue'' and ``cognitive symptoms'', which are not considered as MPS symptoms, are often mistaken for MPS among practicing clinicians. Our findings suggest that the diagnostic criteria are not well known, highlighting the need for an expert consensus to determine the importance of each criterion for MPS diagnosis.

  14. Lung scintigraphy in the diagnosis of pulmonary embolism: current methods and interpretation criteria in clinical practice

    OpenAIRE

    Skarlovnik, Ajda; Hrastnik, Damjana; Fettich, Jure; Grmek, Marko

    2014-01-01

    Background In current clinical practice lung scintigraphy is mainly used to exclude pulmonary embolism (PE). Modified diagnostic criteria for planar lung scintigraphy are considered, as newer scitigraphic methods, especially single photon emission computed tomography (SPECT) are becoming more popular. Patients and methods. Data of 98 outpatients who underwent planar ventilation/perfusion (V/Q) scintigraphy and 49 outpatients who underwent V/Q SPECT from the emergency department (ED) were retr...

  15. Defining Clinical Response Criteria and Early Response Criteria for Precision Oncology: Current State-of-the-Art and Future Perspectives

    Directory of Open Access Journals (Sweden)

    Vivek Subbiah

    2017-02-01

    Full Text Available In this era of precision oncology, there has been an exponential growth in the armamentarium of genomically targeted therapies and immunotherapies. Evaluating early responses to precision therapy is essential for “go” versus “no go” decisions for these molecularly targeted drugs and agents that arm the immune system. Many different response assessment criteria exist for use in solid tumors and lymphomas. We reviewed the literature using the Medline/PubMed database for keywords “response assessment” and various known response assessment criteria published up to 2016. In this article we review the commonly used response assessment criteria. We present a decision tree to facilitate selection of appropriate criteria. We also suggest methods for standardization of various response assessment criteria. The relevant response assessment criteria were further studied for rational of development, key features, proposed use and acceptance by various entities. We also discuss early response evaluation and provide specific case studies of early response to targeted therapy. With high-throughput, advanced computing programs and digital data-mining it is now possible to acquire vast amount of high quality imaging data opening up a new field of “omics in radiology”—radiomics that complements genomics for personalized medicine. Radiomics is rapidly evolving and is still in the research arena. This cutting-edge technology is poised to move soon to the mainstream clinical arena. Novel agents with new mechanisms of action require advanced molecular imaging as imaging biomarkers. There is an urgent need for development of standardized early response assessment criteria for evaluation of response to precision therapy.

  16. Sporadic Creutzfeldt-Jakob disease with focal findings: caveats to current diagnostic criteria

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    Edward C. Mader

    2013-02-01

    Full Text Available The clinical diagnosis of Creutzfeldt-Jakob disease (CJD is largely based on the 1998 World Health Organization diagnostic criteria. Unfortunately, rigid compliance with these criteria may result in failure to recognize sporadic CJD (sCJD, especially early in its course when focal findings predominate and traditional red flags are not yet present. A 61-year-old man presented with a 3-week history of epilepsia partialis continua (jerking of the left upper extremity and a 2-week history of forgetfulness and left hemiparesis; left hemisensory neglect was also detected on admission. Repeated brain magnetic resonance imaging (MRI showed areas of restricted diffusion in the cerebral cortex, initially on the right but later spreading to the left. Electroencephalography (EEG on hospital days 7, 10, and 14 showed right-sided periodic lateralized epileptiform discharges. On day 20, the EEG showed periodic sharp wave complexes leading to a diagnosis of probable sCJD and subsequently to definite sCJD with brain biopsy. Neurological decline was relatively fast with generalized myoclonus and akinetic mutism developing within 7 weeks from the onset of illness. CJD was not immediately recognized because of the patient’s focal/lateralized manifestations. Focal/lateralized clinical, EEG, and MRI findings are not uncommon in sCJD and EEG/MRI results may not be diagnostic in the early stages of sCJD. Familiarity with these caveats and with the most current criteria for diagnosing probable sCJD (University of California San Francisco 2007, MRI-CJD Consortium 2009 will enhance the ability to recognize sCJD and implement early safety measures.

  17. Extrapolating power-ramp performance criteria for current and advanced CANDU fuels

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    Tayal, M.; Chassie, G.G

    2000-06-01

    To improve the precision and accuracy of power-ramp performance criteria for high-burnup fuel, we have examined in-reactor fuel performance data as well as out-reactor test data. The data are consistent with some of the concepts used in the current formulations for defining fuel failure thresholds, such as size of power-ramp and extent of burnup. Our review indicates that there is a need to modify some other aspects of the current formulations; therefore, a modified formulation is presented in this paper. The improvements mainly concern corrodent concentration and its relationships with threshold stress for failure. The new formulation is consistent with known and expected trends such as strength of Zircaloy in corrosive environment, timing of the release of fission products to the pellet-to-sheath gap, CANLUB coating, and fuel burnup. Because of the increased precision and accuracy, the new formulation is better able to identify operational regimes that are at risk of power-ramp failures; this predictive ability provides enhanced protection to fuel against power-ramp defects. At die same time, by removing unnecessary conservatisms in other areas, the new formulation permits a greater range of defect-free operational envelope as well as larger operating margins in regions that are, in fact, not prone to power-ramp failures. (author)

  18. Multi-criteria decision making to support waste management: A critical review of current practices and methods.

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    Goulart Coelho, Lineker M; Lange, Liséte C; Coelho, Hosmanny Mg

    2017-01-01

    Solid waste management is a complex domain involving the interaction of several dimensions; thus, its analysis and control impose continuous challenges for decision makers. In this context, multi-criteria decision-making models have become important and convenient supporting tools for solid waste management because they can handle problems involving multiple dimensions and conflicting criteria. However, the selection of the multi-criteria decision-making method is a hard task since there are several multi-criteria decision-making approaches, each one with a large number of variants whose applicability depends on information availability and the aim of the study. Therefore, to support researchers and decision makers, the objectives of this article are to present a literature review of multi-criteria decision-making applications used in solid waste management, offer a critical assessment of the current practices, and provide suggestions for future works. A brief review of fundamental concepts on this topic is first provided, followed by the analysis of 260 articles related to the application of multi-criteria decision making in solid waste management. These studies were investigated in terms of the methodology, including specific steps such as normalisation, weighting, and sensitivity analysis. In addition, information related to waste type, the study objective, and aspects considered was recorded. From the articles analysed it is noted that studies using multi-criteria decision making in solid waste management are predominantly addressed to problems related to municipal solid waste involving facility location or management strategy.

  19. Making Good Decisions in Healthcare with Multi-Criteria Decision Analysis: The Use, Current Research and Future Development of MCDA.

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    Mühlbacher, Axel C; Kaczynski, Anika

    2016-02-01

    Healthcare decision making is usually characterized by a low degree of transparency. The demand for transparent decision processes can be fulfilled only when assessment, appraisal and decisions about health technologies are performed under a systematic construct of benefit assessment. The benefit of an intervention is often multidimensional and, thus, must be represented by several decision criteria. Complex decision problems require an assessment and appraisal of various criteria; therefore, a decision process that systematically identifies the best available alternative and enables an optimal and transparent decision is needed. For that reason, decision criteria must be weighted and goal achievement must be scored for all alternatives. Methods of multi-criteria decision analysis (MCDA) are available to analyse and appraise multiple clinical endpoints and structure complex decision problems in healthcare decision making. By means of MCDA, value judgments, priorities and preferences of patients, insurees and experts can be integrated systematically and transparently into the decision-making process. This article describes the MCDA framework and identifies potential areas where MCDA can be of use (e.g. approval, guidelines and reimbursement/pricing of health technologies). A literature search was performed to identify current research in healthcare. The results showed that healthcare decision making is addressing the problem of multiple decision criteria and is focusing on the future development and use of techniques to weight and score different decision criteria. This article emphasizes the use and future benefit of MCDA.

  20. The current discussion about the historical Jesus: problems and criteria

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    Andrzej Gieniusz

    2016-07-01

    Full Text Available The article presents the passage from the traditional defense of the historical value of the gospels (which followed the model of a judicial process in which the trustworthiness of witnesses and the eye-witness character of their testimony had to be proved to the contemporary discussion, which for approximately the last fifty years has been developing and refining the criteria of historical reliability, in order to proceed to scrutinize each individual gospel text on these bases. His contribution lays out both the strong points and the weak points of the four criteria which end up being the most spendable and produce the most accurate results: the criteria of double dissimilarity, of multiple testimony, of coherence and of historical plausibility or sufficient explanation.

  1. Chronic migraine and medication overuse headache: clarifying the current International Headache Society classification criteria.

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    Sun-Edelstein, C; Bigal, M E; Rapoport, A M

    2009-04-01

    Despite the recent advances in the understanding and classification of the chronic daily headaches, considerable controversy still exists regarding the classification of individual headaches, including chronic migraine (CM) and medication overuse headache (MOH). The original criteria, published in 2004, were difficult to apply to most patients with these disorders and were subsequently revised, resulting in broader clinical applicability. Nonetheless, they remain a topic of debate, and the revisions to the criteria have further added to the confusion. Even some prominent headache specialists are unsure which criteria to use. We aimed to explain the nature of the controversies surrounding the entities of CM and MOH. A clinical case will be used to illustrate some of the problems faced by clinicians in diagnosing patients with chronic daily headache.

  2. Early response to sibutramine in patients not meeting current label criteria: preliminary analysis of SCOUT lead-in period

    DEFF Research Database (Denmark)

    Caterson, Ian; Coutinho, Walmir; Finer, Nick;

    2010-01-01

    The Sibutramine Cardiovascular Outcomes (SCOUT) trial protocol defines a patient population predominantly outside current European Union label criteria. This article explores responses to sibutramine during the 6-week, single-blind, lead-in period between patients who conformed to the label......-in period. Initial responses were assessed post hoc in label conformers and nonconformers. Of that 8.1% patients met label criteria; 91.9%, the majority with cardiovascular disease and/or blood pressure >145/90 mm Hg, were nonconformers. Conformers and nonconformers had similar reductions in body weight...

  3. Accuracy of Current Diagnostic Criteria for Acute Bacterial Infection in Older Adults in the Emergency Department.

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    Caterino, Jeffrey M; Leininger, Robert; Kline, David M; Southerland, Lauren T; Khaliqdina, Salman; Baugh, Christopher W; Pallin, Daniel J; Stevenson, Kurt B

    2017-08-01

    To compare the accuracy of the Loeb criteria, emergency department (ED) physicians' diagnoses, and Centers for Disease Control and Prevention (CDC) guidelines for acute bacterial infection in older adults with a criterion standard expert review. Prospective, observational study. Urban, tertiary-care ED. Individuals aged 65 and older in the ED, excluding those who were incarcerated, underwent a trauma, did not speak English, or were unable to consent. Two physician experts identified bacterial infections using clinical judgement, participant surveys, and medical records; a third adjudicated in cases of disagreement. Agreement and test characteristics were measured for ED physician diagnosis, Loeb criteria, and CDC surveillance guidelines. Criterion-standard review identified bacterial infection in 77 of 424 participants (18%) (18 (4.2%) lower respiratory, 19 (4.5%) urinary tract (UTI), 22 (5.2%) gastrointestinal, 15 (3.5%) skin and soft tissue). ED physicians diagnosed infection in 71 (17%), but there were 33 with under- and 27 with overdiagnosis. Physician agreement with the criterion standard was moderate for infection overall and each infection type (κ = 0.48-0.59), but sensitivity was low (<67%), and the negative likelihood ratio (LR(-)) was greater than 0.30 for all infections. The Loeb criteria had poor sensitivity, agreement, and LR(-) for lower respiratory (50%, κ = 0.55; 0.51) and urinary tract infection (26%, κ = 0.34; 0.74), but 87% sensitivity (κ = 0.78; LR(-) 0.14) for skin and soft tissue infections. CDC guidelines had moderate agreement but poor sensitivity and LR(-). Emergency physicians often under- and overdiagnose infections in older adults. The Loeb criteria are useful only for diagnosing skin and soft tissue infections. CDC guidelines are inadequate in the ED. New criteria are needed to aid ED physicians in accurately diagnosing infection in older adults. © 2017, Copyright the Authors Journal compilation © 2017, The American Geriatrics

  4. Streptococcus dysgalactiae subsp. equisimilis Isolated From Infections in Dogs and Humans: Are Current Subspecies Identification Criteria accurate?

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    Ciszewski, Marcin; Zegarski, Kamil; Szewczyk, Eligia M

    2016-11-01

    Streptococcus dysgalactiae is a pyogenic species pathogenic both for humans and animals. Until recently, it has been considered an exclusive animal pathogen causing infections in wild as well as domestic animals. Currently, human infections are being reported with increasing frequency, and their clinical picture is often similar to the ones caused by Streptococcus pyogenes. Due to the fact that S. dysgalactiae is a heterogeneous species, it was divided into two subspecies: S. dysgalactiae subsp. equisimilis (SDSE) and S. dysgalactiae subsp. dysgalactiae (SDSD). The first differentiation criterion, described in 1996, was based on strain isolation source. Currently applied criteria, published in 1998, are based on hemolysis type and Lancefield group classification. In this study, we compared subspecies identification results for 36 strains isolated from clinical cases both in humans and animals. Species differentiation was based on two previously described criteria as well as MALDI-TOF and genetic analyses: RISA and 16S rRNA genes sequencing. Antimicrobial susceptibility profiles were also determined according to CLSI guidelines. The results presented in our study suggest that the subspecies differentiation criteria previously described in the above two literature positions seem to be inaccurate in analyzed group of strains, the hemolysis type on blood agar, and Lancefield classification should not be here longer considered as criteria in subspecies identification. The antimicrobial susceptibility tests indicate emerging of multiresistant human SDSE strains resistant also to vancomycin, linezolid and tigecycline, which might pose a substantial problem in treatment.

  5. Biomarkers of Alzheimer disease: current and future applications to diagnostic criteria.

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    Sperling, Reisa; Johnson, Keith

    2013-04-01

    This article reviews recent advances in imaging and fluid biomarkers for Alzheimer disease (AD) and their application to newly proposed diagnostic criteria across the continuum of AD. There have been remarkable developments in neuroimaging markers for AD over the past decade, most notably the advent of positron emission tomography (PET) amyloid imaging using radiotracers that label fibrillar forms of amyloid-β (Aβ). Similarly, new research in CSF markers suggests CSF levels of Aβ1-42 and phosphorylated tau may be useful in the early diagnosis of AD and prediction of cognitive decline. The National Institute on Aging and the Alzheimer's Association recently convened three workgroups to develop joint recommendations for new diagnostic guidelines across the spectrum of AD. These recommendations incorporate biomarkers and propose updated criteria for the previously recognized stage of AD dementia, the evolving definition of mild cognitive impairment, and a newly proposed concept of stages of preclinical AD. Recent advances in AD biomarkers have increased the ability to detect evidence of early AD pathology in vivo. These biomarkers have been incorporated into new diagnostic recommendations, but a number of challenges remain for the biomarkers to become widely applied in clinical practice.

  6. Current status of the quantification of roughness and the peak shear strength criteria for rock joints

    Energy Technology Data Exchange (ETDEWEB)

    Park, Byoung Yoon; Kang, Chul Hyung

    1999-04-01

    In order to understand the effects of spent nuclear fuel on the hydraulic behaviour of the rock mass it is necessary to have knowledge about the relationship between the stresses and hydraulic properties of the fractures. The roughness of a fracture surface govern the dilation of the fracture and the displacement of the fracture surface under shear stress. The peak shear strength and hydraulic flow properties of fractures depend very much on the surface roughness. This report describes different methods and techniques used in the characterization of rock joint surfaces and their applications in rock mechanics. Joint roughness is an important factor in the shear resistance of a joint. The joint shear strength shows anisotropic properties due to roughness variation with the shearing direction in direct shear tests. Various shear strength criteria are described in this report. (author)

  7. South African medical schools: Current state of selection criteria and medical students' demographic profile.

    Science.gov (United States)

    van der Merwe, L J; van Zyl, G J; St Clair Gibson, A; Viljoen, M; Iputo, J E; Mammen, M; Chitha, W; Perez, A M; Hartman, N; Fonn, S; Green-Thompson, L; Ayo-Ysuf, O A; Botha, G C; Manning, D; Botha, S J; Hift, R; Retief, P; van Heerden, B B; Volmink, J

    2015-12-16

    Selection of medical students at South African (SA) medical schools must promote equitable and fair access to students from all population groups, while ensuring optimal student throughput and success, and training future healthcare practitioners who will fulfil the needs of the local society. In keeping with international practices, a variety of academic and non-academic measures are used to select applicants for medical training programmes in SA medical schools. To provide an overview of the selection procedures used by all eight medical schools in SA, and the student demographics (race and gender) at these medical schools, and to determine to what extent collective practices are achieving the goals of student diversity and inclusivity. A retrospective, quantitative, descriptive study design was used. All eight medical schools in SA provided information regarding selection criteria, selection procedures, and student demographics (race and gender). Descriptive analysis of data was done by calculating frequencies and percentages of the variables measured. Medical schools in SA make use of academic and non-academic criteria in their selection processes. The latter include indices of socioeconomic disadvantage. Most undergraduate medical students in SA are black (38.7%), followed by white (33.0%), coloured (13.4%) and Indian/Asian (13.6%). The majority of students are female (62.2%). The number of black students is still proportionately lower than in the general population, while other groups are overrepresented. Selection policies for undergraduate medical programmes aimed at redress should be continued and further refined, along with the provision of support to ensure student success.

  8. How valid and applicable are current diagnostic criteria and assessment methods for dentin hypersensitivity? An overview.

    Science.gov (United States)

    Gernhardt, Christian R

    2013-03-01

    Although dentin hypersensitivity is a common clinical condition and is generally reported by the patient after experiencing a sharp, short pain caused by one of several different external stimuli, it is often inadequately understood. The purpose of this paper is to discuss different available diagnostic approaches and assessment methods used in order to suggest a basis to diagnose, monitor, and measure these challenging painful conditions related to dentin hypersensitivity in daily practice and scientific projects properly. A PubMed literature search strategy including the following MeSH terms were used as follows: "dentin sensitivity"[MeSH Terms] OR "dentin"[All Fields] AND "sensitivity"[All Fields] OR "dentin sensitivity"[All Fields] OR "dentin"[All Fields] AND "hypersensitivity"[All Fields] OR "dentin hypersensitivity"[All Fields] AND "diagnosis"[Subheading] OR "diagnosis"[All Fields] OR "diagnosis"[MeSH Terms] AND "assessment"[All Fields] AND ("methods"[Subheading] OR "methods"[All Fields] OR "methods"[MeSH Terms]. Furthermore, alternative terms such as "validity," "reliability," "root," "cervical," "diagnostic criteria," and "hypersensitivities" were additionally evaluated. The literature search, also including the alternative terms and journals, revealed only a small number of specific papers related to valid diagnosis, diagnostic criteria, and assessment methods of dentin hypersensitivity. Outcomes from these publications showed that the response to different stimuli varies substantially from one person to another and is, due to individual factors, often difficult to assess correctly. Furthermore, the cause of the reported pain can vary, and the patient's description of the history, symptoms, and discomfort might be different from one to another, not allowing a reliable and valid diagnosis. The dental practitioner, using a variety of diagnostic and measurement techniques each day, will often have difficulties in differentiating dentin hypersensitivity from

  9. Criteria for fluxon generation in long Josephson junctions by current pulses

    DEFF Research Database (Denmark)

    Sakai, S.; Samuelsen, Mogens Rugholm

    1987-01-01

    In recent measurements in the time domain on the fluxon shape in long Josephson junctions the fluxons were generated by a current pulse injected into one end. We present here a perturbation treatment of the fluxon generation which we compare with numerical experiments. The agreement turns out to ...... to be excellent. Applied Physics Letters is copyrighted by The American Institute of Physics....

  10. Hypertrophic pachymeningitis: Current criteria for diagnosis and differentiation (Clinical case and review of literature

    Directory of Open Access Journals (Sweden)

    E. G. Mendelevich

    2015-01-01

    Full Text Available The paper describes a 44-year-old male patient with an about 6-year history of hypertrophic pachymeningitis. The major clinical symptoms were characterized by headache, exophthalmos, and blindness in one eye. The data for differential diagnosis of the disease are given. The current literature on the clinical manifestations of hypertrophic pachymeningitis, its differential diagnosis, and the results of magnetic resonance imaging (MRI is reviewed. Diagnostic difficulties at the stage of a clinical observation are due to the nonspecificity of neurological manifestations and the need for a comprehensive examination to detect a somatic disease. MRI can diagnose the disease-specific phenomenon of damage to the meninges, which calls for further careful differentiation. Clinicians must be familiar with alternative differential diagnosis, as a rapid specific therapeutic approach will help avoid long-term or irreversible neurological complications.

  11. Metabolic syndrome in Black people of the African diaspora: the paradox of current classification, definition and criteria.

    Science.gov (United States)

    Gaillard, Trudy; Schuster, Dara; Osei, Kwame

    2009-01-01

    According to the third National Health and Nutrition Examination Survey, African Americans have a lower prevalence of metabolic syndrome than do Whites. Recent reports in Blacks in other regions have confirmed these observations, but the rates vary. This lower rate of metabolic syndrome in Blacks can be partly ascribed to the lower prevalent rates of some major components of metabolic syndrome, namely serum triglyceride and high-density lipoprotein cholesterol levels in Blacks. This is in contrast with the higher prevalence of obesity (waist circumference) and blood pressure that meet National Cholesterol Education Program criteria in Blacks. Despite these seemingly favorable lipids and lipoprotein profiles, Blacks continue to have higher cardiovascular disease (CVD) mortality and morbidity, even in the absence of diabetes, than do Whites. Insulin resistance is more prevalent in Blacks than in Whites. However, the relationships among insulin resistance and CVD risk factors such as hypertension, high-density lipoprotein cholesterol, and triglycerides are weak in contrast with Whites. The paradox of more favorable lipid profile and conversely the higher rates of unfavorable blood pressure in Blacks calls into question the validity of the current criteria for metabolic syndrome in Blacks. Thus, it can be argued that each of the components of the metabolic syndrome carry different CVD risk factors in Blacks. The greater CVD mortality and morbidity in Blacks appear to be multifactorial. With the emerging epidemic of noncommunicable diseases, chronic kidney diseases due to both diabetes and hypertension have emerged as major CVD risks that are associated with increasing mortality and morbidity in Blacks. We need to emphasize specific components of metabolic syndrome, specifically blood pressure and chronic kidney disease, that carry higher CVD risk with associated greater morbidity and mortality for primary prevention of CVD and type 2 diabetes in Blacks. To this end, we

  12. Atypical Alstrom syndrome with novel ALMS1 mutations precluded by current diagnostic criteria.

    LENUS (Irish Health Repository)

    Casey, Jillian

    2014-02-01

    We report on clinical and genetic studies in a non-consanguineous Irish sib-pair with infantile dilated cardiomyopathy and retinopathy. A diagnosis of Alström Syndrome (AS) was considered and diagnostic testing pursued. The Alströms gene (ALMS1) is very large (23 exons) and diagnostic testing of mutational hotspots (exon 6, 8 and 10) was negative. Furthermore the siblings were tall and did not have the typical phenotype of nystagmus, photophobia, obesity or hearing loss and so the AS diagnosis was removed. We then sought to identify the causative gene in this family using whole exome sequencing. Unexpectedly, the exome analysis identified novel compound heterozygous ALMS1 mutations in exon 5 (c.777delT:p.D260fs*26) and exon 20 (c.12145_12146insC:p.S4049fs*36) that segregated with the phenotype. Although the siblings show some clinical overlap with AS, their phenotype is not classical. It is plausible that their atypical presentation may be due to the location of the ALMS1 mutations outside the usual mutational hotspots. Our findings show how atypical cases of AS may be missed under the current diagnostic guidelines and support consideration of complete ALMS1 sequencing in children with two or more features, even if all of the core clinical features of AS are not present.

  13. Recommendations and Justifications To Remove Use Restrictions Established under the U.S. Department of Energy, National Nuclear Security Administration Nevada Field Office Federal Facility Agreement and Consent Order, Revision 0

    Energy Technology Data Exchange (ETDEWEB)

    Birney, Cathleen; Krauss, Mark J

    2013-09-01

    This document is part of an effort to reevaluate 37 FFACO and Administrative URs against the current Soils Risk-Based Corrective Action Evaluation Process. After reviewing 37 existing FFACO and Administrative URs, 3 URs addressed in this document have sufficient information to determine that these current URs may be removed, based on the RBCA criteria. This document presents recommendations on modifications to existing URs that will be consistent with the RBCA criteria.

  14. Recommendations and Justifications for Modifications To Downgrade Use Restrictions Established under the U.S. Department of Energy, National Nuclear Security Administration Nevada Field Office Federal Facility Agreement and Consent Order, Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    Birney, Cathleen; Krauss, Mark J

    2013-10-01

    This document is part of an effort to reevaluate 37 FFACO and Administrative URs against the current Soils Risk-Based Corrective Action Evaluation Process. After reviewing 37 existing FFACO and Administrative URs, 11 URs addressed in this document have sufficient information to determine that these current URs may be downgraded to Administrative URs based on the RBCA criteria. This document presents recommendations on modifications to existing URs that will be consistent with the RBCA criteria.

  15. Cocaine use disorder prevalence: From current DSM-IV to proposed DSM-5 diagnostic criteria with both a two and three severity level classification system.

    Science.gov (United States)

    Proctor, Steven L; Kopak, Albert M; Hoffmann, Norman G

    2014-06-01

    This article presents a secondary analysis from a study investigating the compatibility of the current DSM-IV and previously proposed DSM-5 cocaine use disorder (CUD) criteria (S. L. Proctor, A. M. Kopak, & N. G. Hoffmann, 2012, Compatibility of current DSM-IV and proposed DSM-5 diagnostic criteria for cocaine use disorders. Addictive Behaviors, 37, 722-728). The current analyses examined the compatibility of the current DSM-IV and two sets of proposed DSM-5 diagnostic criteria for CUDs among adult male inmates (N = 6,871) recently admitted to the Minnesota Department of Corrections state prison system from 2000-2003. Initially proposed DSM-5 criteria (DSM-5.0) featured only two diagnostic designations (i.e., moderate and severe). A subsequent revision (DSM-5.1) included the addition of a mild designation and required a greater number of positive findings for the severe designation. A computer-prompted structured diagnostic interview was administered to all inmates as part of routine clinical assessments. The past 12-month prevalence of DSM-IV CUDs was 12.70% (Abuse, 3.78%, Dependence, 8.92%), while 10.98% met past 12-month DSM-5.1 criteria for a CUD (Mild [MiCUD], 1.72%; Moderate [MCUD], 1.12%; and Severe [SCUD], 8.14%). The vast majority of those with no diagnosis (99.6%) continued to have no diagnosis, and most of those with a dependence diagnosis (91.2%) met SCUD criteria of the proposed DSM-5.1. Most of the variation in DSM-5.1 diagnostic classifications was accounted for by those with a current abuse diagnosis. DSM-5.0 MCUD cases were most affected when DSM-5.1 criteria were applied. The proposed diagnostic changes might translate to reduced access to treatment for those individuals evincing symptoms consistent with DSM-IV cocaine abuse.

  16. Comparing Symptoms of Autism Spectrum Disorders Using the Current "DSM-IV-TR" Diagnostic Criteria and the Proposed "DSM-V" Diagnostic Criteria

    Science.gov (United States)

    Worley, Julie A.; Matson, Johnny L.

    2012-01-01

    The American Psychiatric Association has proposed major revisions for the diagnostic category encompassing Autism Spectrum Disorders (ASD), which will reportedly increase the specificity and maintain the sensitivity of diagnoses. As a result, the aim of the current study was to compare symptoms of ASD in children and adolescents (N = 208) who met…

  17. Comparing Symptoms of Autism Spectrum Disorders Using the Current "DSM-IV-TR" Diagnostic Criteria and the Proposed "DSM-V" Diagnostic Criteria

    Science.gov (United States)

    Worley, Julie A.; Matson, Johnny L.

    2012-01-01

    The American Psychiatric Association has proposed major revisions for the diagnostic category encompassing Autism Spectrum Disorders (ASD), which will reportedly increase the specificity and maintain the sensitivity of diagnoses. As a result, the aim of the current study was to compare symptoms of ASD in children and adolescents (N = 208) who met…

  18. Raman spectra of the solid-solution between Rb sub 2 La sub 2 Ti sub 3 O sub 1 sub 0 and RbCa sub 2 Nb sub 3 O sub 1 sub 0

    CERN Document Server

    Kim, H J; Yun, H S

    2001-01-01

    A site preference of niobium atom in Rb sub 2 sub - sub x La sub 2 Ti sub 3 sub - sub x Nb sub x O sub 1 sub 0 (0.0<=x<=1.0) and RbLa sub 2 sub - sub x Ca sub x Ti sub 2 sub - sub x Nb sub 1 sub + sub x O sub 1 sub 0 (0.0<=x<= 2.0), which are the solid-solutions between Rb sub 2 La sub 2 Ti sub 3 O sub 1 sub 0 are RbCa sub 2 Nb sub 3 O sub 1 sub 0 , has been investigated by Raman spectroscopy. The Raman spectra of Rb sub 2 sub - sub x La sub 2 Ti sub 3 sub - sub x Nb sub x O sub 1 sub 0 (0.0<=x<=1.0) gave an evidence that niobium atoms substituted for titanium atoms preferably occupy the highly distorted outer octahedral sites rather than the central ones in triple-octahedral perovskite layers. In contrast, the Raman spectra of RbLa sub 2 sub - sub x Ca sub x Ti sub 2 sub - sub x Nb sub 1 sub + sub x O sub 1 sub 0 (0.0<=x<= 2.0) showed no clear information for the cationic arrangement in perovskite slabs. This difference indicated that a site preference of niobium atoms is observed onl...

  19. The application of strength and power related field tests in older adults : criteria, current status and a future perspective

    NARCIS (Netherlands)

    Regterschot, G. Ruben H.; Morat, Tobias; Folkersma, Marjanne; Zijlstra, Wiebren

    2015-01-01

    Leg muscle strength (LMS) and leg muscle power (LMP) are determinants of aspects of functional status and important parameters for measuring intervention effects in older adults. Field tests are often used for the evaluation of LMS and LMP in older persons. However, criteria important for the applic

  20. The application of strength and power related field tests in older adults : criteria, current status and a future perspective

    NARCIS (Netherlands)

    Regterschot, G. Ruben H.; Morat, Tobias; Folkersma, Marjanne; Zijlstra, Wiebren

    2015-01-01

    Leg muscle strength (LMS) and leg muscle power (LMP) are determinants of aspects of functional status and important parameters for measuring intervention effects in older adults. Field tests are often used for the evaluation of LMS and LMP in older persons. However, criteria important for the applic

  1. The health systems' priority setting criteria for selecting health technologies: A systematic review of the current evidence

    Science.gov (United States)

    Mobinizadeh, Mohammadreza; Raeissi, Pouran; Nasiripour, Amir Ashkan; Olyaeemanesh, Alireza; Tabibi, Seyed Jamaleddin

    2016-01-01

    Background: In the recent years, using health technologies to diagnose and treat diseases has had a considerable and accelerated growth. The proper use of these technologies may considerably help in the diagnosis and treatment of different diseases. On the other hand, unlimited and unrestricted entry of these technologies may result in induced demand by service providers. The aim of this study was to determine the appropriate criteria used in health technologies priority-setting models in the world. Methods: Using MESH and free text, we sought and retrieved the relevant articles from the most appropriate medical databases (the Cochrane Library, PubMed and Scopus) through three separate search strategies up to March 2015. The inclusion criteria were as follows: 1) Studies with specific criteria; 2) Articles written in English; 3) Those articles conducted in compliance with priority setting of health technologies. Data were analyzed qualitatively using a thematic synthesis technique. Results: After screening the retrieved papers via PRISMA framework, from the 7,012 papers, 40 studies were included in the final phase. Criteria for selecting health technologies (in pre assessment and in the assessment phase) were categorized into six main themes: 1) Health outcomes; 2) Disease and target population; 3) Technology alternatives; 4) Economic aspects; 5) Evidence; 6) and other factors. "Health effects/benefits" had the maximum frequency in health outcomes (8 studies); "disease severity" had the maximum frequency in disease and target population (12 studies); "the number of alternatives" had the maximum frequency in alternatives (2 studies); "cost-effectiveness" had the maximum frequency in economic aspects (15 studies); "quality of evidence" had the maximum frequency in evidence (4 studies); and "issues concerning the health system" had the maximum frequency in other factors (10 studies). Conclusion: The results revealed an increase in the number of studies on health

  2. Congestive heart failure and converting enzyme inhibition: failure of current prognostic criteria for predicting subsequent renal insufficiency.

    OpenAIRE

    1991-01-01

    Angiotensin-1-converting enzyme inhibitors have an effective and established role in the treatment of patients with congestive heart failure. However, a small number of such patients will subsequently develop renal insufficiency. These patients may be identified prior to, or shortly after, commencement of therapy by recognized criteria. This report describes 4 patients with congestive heart failure who developed severe renal insufficiency secondary to either enalapril or captopril therapy in ...

  3. Multi-criteria decision-making for flood risk management: a survey of the current state of the art

    Science.gov (United States)

    Madruga de Brito, Mariana; Evers, Mariele

    2016-04-01

    This paper provides a review of multi-criteria decision-making (MCDM) applications to flood risk management, seeking to highlight trends and identify research gaps. A total of 128 peer-reviewed papers published from 1995 to June 2015 were systematically analysed. Results showed that the number of flood MCDM publications has exponentially grown during this period, with over 82 % of all papers published since 2009. A wide range of applications were identified, with most papers focusing on ranking alternatives for flood mitigation, followed by risk, hazard, and vulnerability assessment. The analytical hierarchy process (AHP) was the most popular method, followed by Technique for Order Preference by Similarity to an Ideal Solution (TOPSIS), and Simple Additive Weighting (SAW). Although there is greater interest in MCDM, uncertainty analysis remains an issue and was seldom applied in flood-related studies. In addition, participation of multiple stakeholders has been generally fragmented, focusing on particular stages of the decision-making process, especially on the definition of criteria weights. Therefore, addressing the uncertainties around stakeholders' judgments and endorsing an active participation in all steps of the decision-making process should be explored in future applications. This could help to increase the quality of decisions and the implementation of chosen measures.

  4. The investigation of the effectiveness of the criteria for the construction of a physics text for students with dyslexia: The case of the electric current

    Directory of Open Access Journals (Sweden)

    Panagiotis Papalexopoulos

    2008-01-01

    Full Text Available In this paper we studied the effectiveness of the writing criteria that are proposed to be applied during the construction of physics texts so that students with dyslexia do not confront reading difficulties with them. The effectiveness of the criteria has been assessed by the accomplishment of an investigation among students with and without dyslexia. A physics text that was constructed according to the writing criteria and referred to the concept of the electric current was given to read by all students. Twenty two (22 questions were used in order to assign the recognition of the physical phenomena, the physical quantities, the relations between the physical quantities and the units of measurement by all the students. The results of the investigation showed that the writing criteria helped the students with dyslexia not to have difficulties with the physics text about the “electric current”. The only area that students with dyslexia had some difficulties compared to the students without dyslexia was the recognition of the units of measurement.

  5. Use of physiologically based pharmacokinetic models coupled with pharmacodynamic models to assess the clinical relevance of current bioequivalence criteria for generic drug products containing Ibuprofen.

    Science.gov (United States)

    Cristofoletti, Rodrigo; Dressman, Jennifer B

    2014-10-01

    Physiologically based pharmacokinetic models coupled with pharmacodynamic (PBPK/PD) models can be useful to identify whether current bioequivalence criteria is overly conservative or venturesome for different drugs. A PBPK model constructed with Simcyp Simulator(®) using reported biopharmaceutics parameters for ibuprofen was coupled with two published PD models: one for antipyresis and one for dental pain relief. Using products with doses of 400 mg and 10 mg/kg as "reference (R)" drug products, virtual products with doses of 280 mg and 7 mg/kg, respectively, could be interpreted as representing bioinequivalent test (T) drug products, as the point estimate for the ratios T/R are well below the bioequivalence limits. Despite being bioinequivalent in terms of PK, these lower doses were shown to be therapeutically equivalent to the higher doses because of the flat dose-response relationship of ibuprofen. Sensitivity analysis of the PBPK/PD models demonstrated that gastric emptying time, dissolution rate and small intestine pH are variables that influence ibuprofen PK, but do not seem to significantly affect its PD. It was concluded that current bioequivalent guidance might be unnecessarily restrictive for ibuprofen products.

  6. Alcohol use disorder diagnoses in the criminal justice system: an analysis of the compatibility of current DSM-IV, proposed DSM-5.0, and DSM-5.1 diagnostic criteria in a correctional sample.

    Science.gov (United States)

    Kopak, Albert M; Metze, Amanda V; Hoffmann, Norman G

    2014-06-01

    This study explored the compatibility between the current Diagnostic and Statistical Manual of Mental Disorders (4th ed., text rev.; DSM-IV-TR) diagnostic criteria for alcohol abuse and dependence with the initial (DSM-5.0) and most recent (DSM-5.1) proposed diagnostic criteria. Data drawn from a structured clinical interview used in the assessment of 6,871 male and 801 female state prison inmates were analyzed according to the existing and proposed diagnostic formulations. The greatest congruence was observed in cases that received no diagnosis according to the DSM-IV-TR because these also received no diagnosis in the DSM-5.1. Most cases with a current dependence diagnosis received a severe designation according to the proposed criteria. However, those with an abuse diagnosis were divided across various DSM-5.1 severity levels. Some diagnostic criteria were nearly universally endorsed among those classified with the highest severity levels, which indicated that some criteria may serve as cardinal indicators of a severe alcohol use disorder (SAUD). Additional diagnostic criteria not yet suggested for inclusion in the DSM (i.e., preoccupation with alcohol use and alcohol use to relieve emotional distress) were also evaluated. Evidence demonstrated these two criteria served as functional indicators of alcohol use disorder (AUD). This assessment approach can be used to establish appropriate treatment objectives based on the severity of diagnosed AUDs. Meeting these treatment objectives, especially in a correctional population, may have important implications for future offending. Recommendations are made for prospective research in this area.

  7. Recommendations and Justifications for Modifications for Use Restrictions Established under the U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office Federal Facility Agreement and Consent Order, Revision 0

    Energy Technology Data Exchange (ETDEWEB)

    Lynn Kidman

    2008-02-01

    This document is part of an effort to re-evaluate all FFACO URs against the current RBCA criteria (referred to in this document as the Industrial Sites [IS] RBCA process) as defined in the Industrial Sites Project Establishment of Final Action Levels (NNSA/NSO, 2006c). Based on this evaluation, the URs were sorted into the following categories: 1. Where sufficient information exists to determine that the current UR is consistent with the RCBA criteria 2. Where sufficient information exists to determine that the current UR may be removed or downgraded based on RCBA criteria. 3. Where sufficient information does not exist to evaluate the current UR against the RCBA criteria. After reviewing all the existing FFACO URs, the 49 URs addressed in this document have sufficient information to determine that these current URs may be removed or downgraded based on RCBA criteria. This document presents recommendations on modifications to existing URs that will be consistent with the RCBA criteria.

  8. Review Article: Multi-criteria decision making for flood risk management: a survey of the current state-of-the-art

    Science.gov (United States)

    de Brito, M. M.; Evers, M.

    2015-11-01

    This paper provides a review of Multi-Criteria Decision Making (MCDM) applications to flood risk management, seeking to highlight trends and identify research gaps. Totally, 128 peer-reviewed papers published from 1995 to June 2015 were systematically analysed and classified into the following application areas: (1) ranking of alternatives for flood mitigation, (2) reservoir flood control, (3) susceptibility, (4) hazard, (5) vulnerability, (6) risk, (7) coping capacity, and (8) emergency management. Additionally, the articles were categorized based on the publication year, MCDM method, whether they were or were not carried out in a participatory process, and if uncertainty and sensitivity analysis were performed. Results showed that the number of flood MCDM publications has exponentially grown during this period, with over 82 % of all papers published since 2009. The Analytical Hierarchy Process (AHP) was the most popular technique, followed by Technique for Order Preference by Similarity to an Ideal Solution (TOPSIS), and Simple Additive Weighting (SAW). Although there is greater interest on MCDM, uncertainty analysis remains an issue and is seldom applied in flood-related studies. In addition, participation of multiple stakeholders has been generally fragmented, focusing on particular stages of the decision-making process, especially on the definition of criteria weights. Based on the survey, some suggestions for further investigation are provided.

  9. The cytologic criteria of malignancy.

    Science.gov (United States)

    Fischer, Andrew H; Zhao, Chengquan; Li, Qing Kay; Gustafson, Karen S; Eltoum, Isam-Eldin; Tambouret, Rosemary; Benstein, Barbara; Savaloja, Lynnette C; Kulesza, Peter

    2010-07-01

    Cytology and cell biology are two separate fields that share a focus on cancer. Cancer is still diagnosed based on morphology, and surprisingly little is known about the molecular basis of the defining structural features. Cytology uses the smallest possible biopsy for diagnosis by reducing morphologic "criteria of malignancy" to the smallest scale. To begin to develop common ground, members of the American Society of Cytopathology Cell Biology Liaison Working Group classify some of the "criteria of malignancy" and review their relation to current cell biology concepts. The criteria of malignancy are extremely varied, apparently reflecting many different pathophysiologies in specific microenvironments. Criteria in Group 1 comprise tissue-level alterations that appear to relate to resistance to anoikis, alterations in cell adhesion molecules, and loss of apical-basal polarity. Criteria in Group 2 reflect genetic instability, including chromosomal and possibly epigenetic instability. Criteria in Groups 3 are subcellular structural changes involving cytoplasmic components, nuclear lamina, chromatin and nucleoli that cannot be accounted for by genetic instability. Some distinct criteria in Group 3 are known to be induced by cancer genes, but their precise structural basis remains obscure. The criteria of malignancy are not closely related to the histogenetic classification of cancers, and they appear to provide an alternative, biologically relevant framework for establishing common ground between cytologists and cell biologists. To understand the criteria of malignancy at a molecular level would improve diagnosis, and likely point to novel cell physiologies that are not encompassed by current cell biology concepts.

  10. GNS-12 Packaging design criteria

    Energy Technology Data Exchange (ETDEWEB)

    Clements, E.P., Westinghouse Hanford

    1996-07-24

    The purpose of this Packaging Design Criteria (PDC) is to provide criteria for the Safety Analysis Report for Packaging (SARP)(Onsite). The SARP provides the evaluation to demonstrate that the onsite transportation safety criteria are met for the transport and storage of the 324 Building vitrified encapsulated material in the GNS-12 cask. In this application, the approved PDC provides a formal set of standards for the payload requirements, and guidance for the current cask transport configuration and a revised storage seal and primary lid modification design.

  11. Recommendations and Justifications for Modifications for Use Restrictions Established under the U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office Federal Facility Agreement and Consent Order with ROTC 1, Revision No. 0

    Energy Technology Data Exchange (ETDEWEB)

    Lynn Kidman

    2008-02-01

    Many Federal Facility Agreement and Consent Order (FFACO) Use Restrictions (URs) have been established at various corrective action sites (CASs) as part of FFACO corrective actions (FFACO, 1996; as amended January 2007). Since the signing of the FFACO in 1996, practices and procedures relating to the implementation of risk-based corrective action (RBCA) have evolved. This document is part of an effort to re-evaluate all FFACO URs against the current RBCA criteria (referred to in this document as the Industrial Sites [IS] RBCA process) as defined in the Industrial Sites Project Establishment of Final Action Levels (NNSA/NSO, 2006c). Based on this evaluation, the URs were sorted into the following categories: 1. Where sufficient information exists to determine that the current UR is consistent with the RCBA criteria 2. Where sufficient information exists to determine that the current UR may be removed or downgraded based on RCBA criteria. 3. Where sufficient information does not exist to evaluate the current UR against the RCBA criteria. After reviewing all the existing FFACO URs, the 49 URs addressed in this document have sufficient information to determine that these current URs may be removed or downgraded based on RCBA criteria. This document presents recommendations on modifications to existing URs that will be consistent with the RCBA criteria.

  12. Diagnostic criteria for autoimmune chronic pancreatitis revisited

    Institute of Scientific and Technical Information of China (English)

    Kyu-Pyo Kim; Myung-Hwan Kim; Jong Cheol Kim; Sang Soo Lee; Dong Wan Seo; Sung Koo Lee

    2006-01-01

    Autoimmune chronic pancreatitis (AIP) is increasingly being recognized worldwidely, as knowledge of this entity builds up. Above all, AIP is a very attractive disease to clinicians in terms of its dramatic response to the oral steroid therapy in contrast to ordinary chronic pancreatitis. Although many characteristic findings of AIP have been described, definite diagnostic criteria have not been fully established. In the year 2002, the Japan Pancreas Society published the diagnostic criteria of AIP and many clinicians around the world use these criteria for the diagnosis of AIP. The diagnostic criteria proposed by the Japan Pancreas Society, however, are not completely satisfactory and some groups use their own criteria in reporting AIP. This review discusses several potential limitations of current diagnostic criteria for this increasingly recognized condition. The manuscript is organized to emphasize the need for convening a consensus to develop improved diagnostic criteria.

  13. MDS clinical diagnostic criteria for Parkinson's disease.

    Science.gov (United States)

    Postuma, Ronald B; Berg, Daniela; Stern, Matthew; Poewe, Werner; Olanow, C Warren; Oertel, Wolfgang; Obeso, José; Marek, Kenneth; Litvan, Irene; Lang, Anthony E; Halliday, Glenda; Goetz, Christopher G; Gasser, Thomas; Dubois, Bruno; Chan, Piu; Bloem, Bastiaan R; Adler, Charles H; Deuschl, Günther

    2015-10-01

    This document presents the Movement Disorder Society Clinical Diagnostic Criteria for Parkinson's disease (PD). The Movement Disorder Society PD Criteria are intended for use in clinical research but also may be used to guide clinical diagnosis. The benchmark for these criteria is expert clinical diagnosis; the criteria aim to systematize the diagnostic process, to make it reproducible across centers and applicable by clinicians with less expertise in PD diagnosis. Although motor abnormalities remain central, increasing recognition has been given to nonmotor manifestations; these are incorporated into both the current criteria and particularly into separate criteria for prodromal PD. Similar to previous criteria, the Movement Disorder Society PD Criteria retain motor parkinsonism as the core feature of the disease, defined as bradykinesia plus rest tremor or rigidity. Explicit instructions for defining these cardinal features are included. After documentation of parkinsonism, determination of PD as the cause of parkinsonism relies on three categories of diagnostic features: absolute exclusion criteria (which rule out PD), red flags (which must be counterbalanced by additional supportive criteria to allow diagnosis of PD), and supportive criteria (positive features that increase confidence of the PD diagnosis). Two levels of certainty are delineated: clinically established PD (maximizing specificity at the expense of reduced sensitivity) and probable PD (which balances sensitivity and specificity). The Movement Disorder Society criteria retain elements proven valuable in previous criteria and omit aspects that are no longer justified, thereby encapsulating diagnosis according to current knowledge. As understanding of PD expands, the Movement Disorder Society criteria will need continuous revision to accommodate these advances. © 2015 International Parkinson and Movement Disorder Society.

  14. [Diagnostic criteria for neuromyelitisoptica spectrum disorders].

    Science.gov (United States)

    Belova, A N; Boiko, A N; Belova, E M

    2016-01-01

    The review is devoted to revised international diagnostic criteria for neuromyelitisoptica spectrum disorders (NMOSD).Current diagnostic criteria allow NMOSD diagnosis not only for serum aquaporin-4 immunoglobulin G antibodies (AQP4-IgG)-seropositive patients but for AQP4-IgG-seronegative patients as well. New criteria are expected to make NMOSD diagnosis earlier and more accurate as well as to facilitate the differentiation with multiple sclerosis. Furthermore, unify international criteria should help to perform comparable epidemiologic studies and clinical trials of new drugs for NMOSD.

  15. Criteria for Environmentally Associated Autoimmune Diseases

    Science.gov (United States)

    Pollard, K. Michael; Parks, Christine G.; Germolec, Dori R.; Leung, Patrick S.C.; Selmi, Carlo; Humble, Michael C.; Rose, Noel R.

    2012-01-01

    Increasing evidence supports a role for the environment in the development of autoimmune diseases, as reviewed in the accompanying three papers from the National Institute of Environmental Health Sciences Expert Panel Workshop. An important unresolved issue, however, is the development of criteria for identifying autoimmune disease phenotypes for which the environment plays a causative role, herein referred to as environmentally associated autoimmune diseases. There are several different areas in which such criteria need to be developed, including: 1) identifying the necessary and sufficient data to define environmental risk factors for autoimmune diseases meeting current classification criteria; 2) establishing the existence of and criteria for new environmentally associated autoimmune disorders that do not meet current disease classification criteria; and 3) identifying in clinical practice specific environmental agents that induce autoimmune disease in individual patients. Here we discuss approaches that could be useful for developing criteria in these three areas, as well as factors that should be considered in evaluating the evidence for criteria that can distinguish individuals with such disorders from individuals without such disorders with high sensitivity and specificity. Current studies suggest that multiple lines of complementary evidence will be important and that in many cases there will be clinical, serologic, genetic, epigenetic, and/or other laboratory features that could be incorporated as criteria for environmentally associated autoimmune diseases to improve diagnosis and treatment and possibly allow for preventative strategies in the future. PMID:22771005

  16. Green Supplier Selection Criteria

    DEFF Research Database (Denmark)

    Nielsen, Izabela Ewa; Banaeian, Narges; Mobli, Hossein

    2014-01-01

    Green supplier selection (GSS) criteria arise from an organization inclination to respond to any existing trends in environmental issues related to business management and processes, so GSS is integrating environmental thinking into conventional supplier selection. This research is designed...... to determine prevalent general and environmental supplier selection criteria and develop a framework which can help decision makers to determine and prioritize suitable green supplier selection criteria (general and environmental). In this research we considered several parameters (evaluation objectives......) to establish suitable criteria for GSS such as their production type, requirements, policy and objectives instead of applying common criteria. At first a comprehensive and deep review on prevalent and green supplier selection literatures performed. Then several evaluation objectives defined to assess the green...

  17. Plutonium storage criteria

    Energy Technology Data Exchange (ETDEWEB)

    Chung, D. [Scientech, Inc., Germantown, MD (United States); Ascanio, X. [Dept. of Energy, Germantown, MD (United States)

    1996-05-01

    The Department of Energy has issued a technical standard for long-term (>50 years) storage and will soon issue a criteria document for interim (<20 years) storage of plutonium materials. The long-term technical standard, {open_quotes}Criteria for Safe Storage of Plutonium Metals and Oxides,{close_quotes} addresses the requirements for storing metals and oxides with greater than 50 wt % plutonium. It calls for a standardized package that meets both off-site transportation requirements, as well as remote handling requirements from future storage facilities. The interim criteria document, {open_quotes}Criteria for Interim Safe Storage of Plutonium-Bearing Solid Materials{close_quotes}, addresses requirements for storing materials with less than 50 wt% plutonium. The interim criteria document assumes the materials will be stored on existing sites, and existing facilities and equipment will be used for repackaging to improve the margin of safety.

  18. Fire protection design criteria

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    This Standard provides supplemental fire protection guidance applicable to the design and construction of DOE facilities and site features (such as water distribution systems) that are also provided for fire protection. It is intended to be used in conjunction with the applicable building code, national Fire Protection Association Codes and Standards, and any other applicable DOE construction criteria. This Standard, along with other delineated criteria, constitutes the basic criteria for satisfying DOE fire and life safety objectives for the design and construction or renovation of DOE facilities.

  19. Aquatic Life Criteria - Atrazine

    Science.gov (United States)

    Documents pertaining to Acute and Chronic Ambient Water Quality Aquatic Life Criteria for Atrazine (Freshwater and Salt Water). This document contains the safe levels of Atrazine in water that should protect to the majority of species.

  20. Decision criteria of potential solar IPH adapters

    Science.gov (United States)

    Perwin, E.; Levine, A.; Mikasa, G.; Noun, R. J.; Schaller, D.

    1981-12-01

    If national programs are to be effective in the research and development of viable renewable resource technologies for the industrial sector, understanding industry's decision criteria will be important. The results of a preliminary investigation of the decision criteria of potential and actual users of solar industrial process heat systems are presented. Detailed interviews were completed with decision-makers from ten manufacturing firms. Based on economic theory, it was assumed that corporate decision-makers assess the expected cost, revenue, and uncertainty of competing investment opportunities. These decision criteria are composed of factors that are financial, technical, and institutional. Clearly, the firms interviewed were more concerned with costs than any other category of decision criteria. Most of the firms also believed that there was less uncertainty with competing investments than with current solar technology. Based on this preliminary investigation, a more extensive survey of industrial firms is suggested to determine a more comprehensive list of significant decision criteria.

  1. Ready or Not? Criteria for Marriage Readiness among Emerging Adults

    Science.gov (United States)

    Carroll, Jason S.; Badger, Sarah; Willoughby, Brian J.; Nelson, Larry J.; Madsen, Stephanie D.; Barry, Carolyn McNamara

    2009-01-01

    This study examined emerging adults' criteria for marriage readiness and explored how these criteria are associated with their current attitudes and behaviors. This article establishes the psychometric value of the Criteria for Marriage Readiness Questionnaire and reports on a study of 788 emerging adults recruited from five college sites across…

  2. Panel Discussion on Inducer Design Criteria

    Directory of Open Access Journals (Sweden)

    Marc Wegner

    2003-01-01

    Full Text Available This article reports a panel discussion titled Inducer Design Criteria presented at the 9th International Symposium on Transport Phenomena and Dynamics of Rotating Machinery (ISROMAC-9. The presentations of the panelists and the subsequent discussions are summarized. It is shown that cavitation instabilities are major problems in modern turbopumps and that design criteria to eliminate them are needed. Available design methods for inducers and marine propellers are reviewed, and new criteria to enhance stability are proposed. The current status of CFD is reviewed and an example of successful application is shown. Discussions of several specific topics are reported and future research needs are noted.

  3. Dual Criteria Decisions

    DEFF Research Database (Denmark)

    Andersen, Steffen; Harrison, Glenn W.; Lau, Morten Igel;

    2014-01-01

    The most popular models of decision making use a single criterion to evaluate projects or lotteries. However, decision makers may actually consider multiple criteria when evaluating projects. We consider a dual criteria model from psychology. This model integrates the familiar tradeoffs between...... risk and utility that economists traditionally assume, allowance for rank-dependent decision weights, and consideration of income thresholds. We examine the issues involved in full maximum likelihood estimation of the model using observed choice data. We propose a general method for integrating...... the multiple criteria, using the logic of mixture models, which we believe is attractive from a decision-theoretic and statistical perspective. The model is applied to observed choices from a major natural experiment involving intrinsically dynamic choices over highly skewed outcomes. The evidence points...

  4. Meteor Stream Membership Criteria

    CERN Document Server

    Klacka, J

    2000-01-01

    Criteria for the membership of individual meteors in meteor streams are discussed from the point of view of their mathematical and also physical properties. Discussion is also devoted to the motivation. It is shown that standardly used criteria (mainly D-criterion of Southworth and Hawkins, 1963) have unusual mathematical properties in the sense of a term ``distance'', between points in a phase space, and, physical motivation and realization for the purpose of obtaining their final form is not natural and correct, and, moreover, they lead also to at least surprising astrophysical results. General properties of possible criteria are discussed. A new criterion for the membership in meteor streams is suggested. It is based on probability theory. Finally, a problem of meteor orbit determination for known parent body is discussed.

  5. Supplemental Investigation Plan for FFACO Use Restrictions, Nevada Test Site, Nevada, Revision 0

    Energy Technology Data Exchange (ETDEWEB)

    Lynn Kidman

    2008-02-01

    This document is part of an effort to re-evaluate all FFACO URs against the current RBCA criteria (referred to in this document as the Industrial Sites [IS] RBCA process) as defined in the Industrial Sites Project Establishment of Final Action Levels (NNSA/NSO, 2006a). After reviewing all of the existing FFACO URs, the 12 URs addressed in this Supplemental Investigation Plan (SIP) could not be evaluated against the current RBCA criteria as sufficient information about the contamination at each site was not available. This document presents the plan for conducting field investigations to obtain the needed information. This SIP includes URs from Corrective Action Units (CAUs) 326, 339, 358, 452, 454, 464, and 1010, located in Areas 2, 6, 12, 19, 25, and 29 of the Nevada Test Site, which is approximately 65 miles northwest of Las Vegas, Nevada; and CAU 403, located in Area 3 of the Tonopah Test Range, which is approximately 165 miles north of Las Vegas, Nevada.

  6. History and Evolution of the Johnson Criteria.

    Energy Technology Data Exchange (ETDEWEB)

    Sjaardema, Tracy A. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Smith, Collin S. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Birch, Gabriel Carisle [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States)

    2015-07-01

    The Johnson Criteria metric calculates probability of detection of an object imaged by an optical system, and was created in 1958 by John Johnson. As understanding of target detection has improved, detection models have evolved to better model additional factors such as weather, scene content, and object placement. The initial Johnson Criteria, while sufficient for technology and understanding at the time, does not accurately reflect current research into target acquisition and technology. Even though current research shows a dependence on human factors, there appears to be a lack of testing and modeling of human variability.

  7. Human Systems Design Criteria

    DEFF Research Database (Denmark)

    Rasmussen, Jens

    1982-01-01

    the necessary functional qualities but also the needed human qualities. The author's main argument is, that the design process should be a dialectical synthesis of the two points of view: Man as a System Component, and System as Man's Environment. Based on a man's presentation of the state of the art a set...... of design criteria is suggested and their relevance discussed. The point is to focus on the operator rather than on the computer. The crucial question is not to program the computer to work on its own conditions, but to “program” the operator to function on human conditions.......This paper deals with the problem of designing more humanised computer systems. This problem can be formally described as the need for defining human design criteria, which — if used in the design process - will secure that the systems designed get the relevant qualities. That is not only...

  8. Robustness - acceptance criteria

    DEFF Research Database (Denmark)

    Rizzuto, Enrico; Sørensen, John Dalsgaard; Kroon, Inger B.

    2010-01-01

    This factsheet describes the general framework on the bases of which acceptance criteria for requirements on the robustness of structures can be set. Such framework is based on the more general concept of risk-based assessment of engineering systems. The present factsheet is to be seen in conjunc......This factsheet describes the general framework on the bases of which acceptance criteria for requirements on the robustness of structures can be set. Such framework is based on the more general concept of risk-based assessment of engineering systems. The present factsheet is to be seen...... in conjunction with the one on the theoretical framework for robustness (Sørensen et al. 2009). In the present factsheet, the focus is on normative implications....

  9. New classification criteria for gout: a framework for progress

    Science.gov (United States)

    Dalbeth, Nicola; Fransen, Jaap; Jansen, Tim L.; Neogi, Tuhina; Schumacher, H. Ralph; Taylor, William J.

    2013-01-01

    The definitive classification or diagnosis of gout normally relies upon the identification of MSU crystals in SF or from tophi. Where microscopic examination of SF is not available or is impractical, the best approach may differ depending upon the context. For many types of research, clinical classification criteria are necessary. The increasing prevalence of gout, advances in therapeutics and the development of international research collaborations to understand the impact, mechanisms and optimal treatment of this condition emphasize the need for accurate and uniform classification criteria for gout. Five clinical classification criteria for gout currently exist. However, none of the currently available criteria has been adequately validated. An international project is currently under way to develop new validated gout classification criteria. These criteria will be an essential step forward to advance the research agenda in the modern era of gout management. PMID:23611919

  10. On materials destruction criteria

    OpenAIRE

    Kremnev, L. S.

    2015-01-01

    In terms of nonlinear material fracture mechanics, the real (discrete)-structure material fracture model has been developed. The model rests on the demonstration of the fact that crack resistance $K_{1c}=2\\sigma \\sqrt l$ and fracture toughness are $G_{1c}=J_{1c}=2\\sigma l$ obtained on the basis of energy conservation law and derived without linear material fracture mechanics assumptions can be respectively taken as force and energy criteria for non-linear fracture mechanics. It is shown that ...

  11. Web site Evaluation Criteria

    Directory of Open Access Journals (Sweden)

    Mojdgan binesh

    2008-07-01

    Full Text Available The ever-increasing evolution of the Internet and the growing number of the resources accessible through this medium, has turned the issue of resource evaluation of the internet-based information into a controversial and cogent issue. By nature, the internet milieu is uncontrollable. It concomitantly contains both verifiable and unverifiable information. Thus it behooves the internet users to develop resource evaluation and critical thinking skills in order to discern appropriate quality resources. Through review and comparison of the available checklists, the present paper endeavors to offer criteria for website evaluation

  12. PERFORMANCE CRITERIA SLITTING-PROCESS

    Directory of Open Access Journals (Sweden)

    N. V. Starkov

    2016-01-01

    Full Text Available Criteria of efficiency the slitting process. For example double-line rolling of rebar No. 20 identified such criteria separation efficiency in non-dividing device as the size of the crossbar.

  13. National Recommended Water Quality Criteria

    Data.gov (United States)

    U.S. Environmental Protection Agency — The National Recommended Water Quality Criteria is a compilation of national recommended water quality criteria for the protection of aquatic life and human health...

  14. Criteria for Assessing Naturalistic Inquiries as Reports.

    Science.gov (United States)

    Lincoln, Yvonna S.; Guba, Egon G.

    Research on the assessment of naturalistic inquiries is reviewed, and criteria for assessment are outlined. Criteria reviewed include early foundational and non-foundational criteria, trustworthiness criteria, axiomatic criteria, rhetorical criteria, action criteria, and application/transferability criteria. Case studies that are reports of…

  15. The Web Application Test Based on Page Coverage Criteria

    Institute of Scientific and Technical Information of China (English)

    CAI Li-zhi; TONG Wei-qin; YANG Gen-xing

    2008-01-01

    Software testing coverage criteria play an important role in the whole testing process. The current coverage criteria for web applications are based on program or URL. They are not suitable for black-box test or intuitional to use. This paper defines a kind of test criteria based on page coverage sequences only navigated by web application, including Page_Single, Page_Post, Page_Pre,Page_Seq2, Page_SeqK. The test criteria based on page coverage sequences made by interactions between web application and browser are being under consideration after that. In order to avoid ambiguity of natural language, these coverage criteria are depicted using Z formal language. The empirical result shows that the criteria complement traditional coverage and fault detection capability criteria.

  16. Criteria for Restructuring Postsecondary Education.

    Science.gov (United States)

    Slaughter, Sheila

    1995-01-01

    Criteria most often used by higher education administrators in restructuring higher education in the 1980s and 1990s are outlined. A distinction is made between retrenchment and restructuring. Criteria recommended in the literature are compared with criteria actually used, and the results. Some alternatives are suggested. (MSE)

  17. Diagnostic Criteria for Pediatric MS

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap

    2013-06-01

    Full Text Available Investigators at Northwestern University Feinberg School of Medicine and Ann & Robert H. Lurie Children’s Hospital of Chicago review the diagnostic criteria for pediatric multiple sclerosis, the differential diagnosis, the 2010 McDonald criteria, and Callen criteria.

  18. Laser Safety Inspection Criteria

    Energy Technology Data Exchange (ETDEWEB)

    Barat, K

    2005-06-13

    A responsibility of the Laser Safety Officer (LSO) is to perform laser audits. The American National Standard Z136.1 Safe Use of Lasers references this requirement through several sections. One such reference is Section 1.3.2.8, Safety Features Audits, ''The LSO shall ensure that the safety features of the laser installation facilities and laser equipment are audited periodically to assure proper operation''. The composition, frequency and rigor of that inspection/audit rests in the hands of the LSO. A common practice for institutions is to develop laser audit checklists or survey forms It is common for audit findings from one inspector or inspection to the next to vary even when reviewing the same material. How often has one heard a comment, ''well this area has been inspected several times over the years and no one ever said this or that was a problem before''. A great number of audit items, and therefore findings, are subjective because they are based on the experience and interest of the auditor to particular items on the checklist. Beam block usage, to one set of eyes might be completely adequate, while to another, inadequate. In order to provide consistency, the Laser Safety Office of the National Ignition Facility Directorate has established criteria for a number of items found on the typical laser safety audit form. The criteria are distributed to laser users. It serves two broad purposes; first, it gives the user an expectation of what will be reviewed by an auditor. Second, it is an opportunity to explain audit items to the laser user and thus the reasons for some of these items, such as labelling of beam blocks.

  19. Plugging criteria for WWER SG tubes

    Energy Technology Data Exchange (ETDEWEB)

    Papp, L.; Wilam, M. [Vitkovice NPP Services (Switzerland); Herman, M. [Vuje, Trnava (Slovakia)

    1997-12-31

    At operated Czech and Slovak nuclear power plants the 80 % criteria for crack or other bulk defect depth is used for steam generator heat exchanging tubes plugging. This criteria was accepted as the recommendation of designer of WWER steam generators. Verification of this criteria was the objective of experimental program performed by Vitkovice, J.S.C., UJV Rez, J.S.C. and Vuje Trnava, J.S.C .. Within this program the following factors were studied: (1) Influence of secondary water chemistry on defects initiation and propagation, (2) Statistical evaluation of corrosion defects progression at operated SG, and (3) Determination of critical pressure for tube rupture as a function of eddy current indications. In this presentation items (2) and (3) are considered.

  20. Decision criteria in PSA applications

    Energy Technology Data Exchange (ETDEWEB)

    Holmberg, J.E.; Pulkkinen, U.; Rosqvist, T.; Simola, K. [VTT Automation (Finland)

    2001-11-01

    Along with the adoption of risk informed decision making principles, the need for formal probabilistic decision rule or criteria has been risen. However, there are many practical and theoretical problems in the application of probabilistic criteria. One has to think what is the proper way to apply probabilistic rules together with deterministic ones and how the criteria are weighted with respect to each other. In this report, we approach the above questions from the decision theoretic point of view. We give a short review of the most well known probabilistic criteria, and discuss examples of their use. We present a decision analytic framework for evaluating the criteria, and we analyse how the different criteria behave under incompleteness or uncertainty of the PSA model. As the conclusion of our analysis we give recommendations on the application of the criteria in different decision situations. (au)

  1. User perspectives on relevance criteria

    DEFF Research Database (Denmark)

    Maglaughlin, Kelly L.; Sonnenwald, Diane H.

    2002-01-01

    matter, thought catalyst), full text (e.g., audience, novelty, type, possible content, utility), journal/publisher (e.g., novelty, main focus, perceived quality), and personal (e.g., competition, time requirements). Results further indicate that multiple criteria are used when making relevant, partially...... relevant, and not-relevant judgments, and that most criteria can have either a positive or negative contribution to the relevance of a document. The criteria most frequently mentioned by study participants were content, followed by criteria characterizing the full text document. These findings may have...... implications for relevance feedback in information retrieval systems, suggesting that systems accept and utilize multiple positive and negative relevance criteria from users. Systems designers may want to focus on supporting content criteria followed by full text criteria as these may provide the greatest cost...

  2. The Criteria for Determining the Business Failure

    Directory of Open Access Journals (Sweden)

    Luminiţa TULEAŞCĂ

    2012-03-01

    Full Text Available The business failure represents a current problem in any economic and social context and, for this reason, the legislator has been concerned with the regulation of the criteria based on which to accurately determine the failure of a business man when the case. The liquidity test and the balance sheet test, or the insolvency and insolvability are the criteria for determining the business failure usually materialized by undergoing the bankruptcy procedure. The legislator’s option for one or another of these criteria represents a structural option depending on the legal culture of each state however, considering the economic causes and effects of the insolvability and insolvency, that tends to remove the unilateral, exclusivist options. This paper illustrates significant option differences between the criteria for determining the business failure in the member states of the European Union which is the most used criterion and, if these criteria can be equally used in the banking and insurance sector. Last but not least, the paper illustrates the meanings of insolvency and insolvability in different matters and different laws and the need to eliminate the reserve that the Romanian doctrine manifests towards the insolvability concept as a cause for bankruptcy.

  3. DOE Standard: Fire protection design criteria

    Energy Technology Data Exchange (ETDEWEB)

    1999-07-01

    The development of this Standard reflects the fact that national consensus standards and other design criteria do not comprehensively or, in some cases, adequately address fire protection issues at DOE facilities. This Standard provides supplemental fire protection guidance applicable to the design and construction of DOE facilities and site features (such as water distribution systems) that are also provided for fire protection. It is intended to be used in conjunction with the applicable building code, National Fire Protection Association (NFPA) Codes and Standards, and any other applicable DOE construction criteria. This Standard replaces certain mandatory fire protection requirements that were formerly in DOE 5480.7A, ``Fire Protection``, and DOE 6430.1A, ``General Design Criteria``. It also contains the fire protection guidelines from two (now canceled) draft standards: ``Glove Box Fire Protection`` and ``Filter Plenum Fire Protection``. (Note: This Standard does not supersede the requirements of DOE 5480.7A and DOE 6430.1A where these DOE Orders are currently applicable under existing contracts.) This Standard, along with the criteria delineated in Section 3, constitutes the basic criteria for satisfying DOE fire and life safety objectives for the design and construction or renovation of DOE facilities.

  4. Classification criteria for systemic lupus erythematosus: a review.

    Science.gov (United States)

    Petri, M; Magder, L

    2004-01-01

    The Systemic Lupus International Collaborating Clinics, in preparation for revising the ACR classification criteria for systemic lupus erythematosus, reviewed the current classification criteria. These critical reviews, discussed at the Lund, Sweden, meeting in 2003, will be useful to the clinician and to the researcher. This paper reviews and critiques previous classification attempts.

  5. FHR Generic Design Criteria

    Energy Technology Data Exchange (ETDEWEB)

    Flanagan, G.F.; Holcomb, D.E.; Cetiner, S.M.

    2012-06-15

    The purpose of this document is to provide an initial, focused reference to the safety characteristics of and a licensing approach for Fluoride-Salt-Cooled High-Temperature Reactors (FHRs). The document does not contain details of particular reactor designs nor does it attempt to identify or classify either design basis or beyond design basis accidents. Further, this document is an initial attempt by a small set of subject matter experts to document the safety and licensing characteristics of FHRs for a larger audience. The document is intended to help in setting the safety and licensing research, development, and demonstration path forward. Input from a wider audience, further technical developments, and additional study will be required to develop a consensus position on the safety and licensing characteristics of FHRs. This document begins with a brief overview of the attributes of FHRs and then a general description of their anticipated safety performance. Following this, an overview of the US nuclear power plant approval process is provided that includes both test and power reactors, as well as the role of safety standards in the approval process. The document next describes a General Design Criteria (GDC)–based approach to licensing an FHR and provides an initial draft set of FHR GDCs. The document concludes with a description of a path forward toward developing an FHR safety standard that can support both a test and power reactor licensing process.

  6. FHR Generic Design Criteria

    Energy Technology Data Exchange (ETDEWEB)

    Flanagan, George F [ORNL; Holcomb, David Eugene [ORNL; Cetiner, Sacit M [ORNL

    2012-06-01

    The purpose of this document is to provide an initial, focused reference to the safety characteristics of and a licensing approach for Fluoride-Salt-Cooled High-Temperature Reactors (FHRs). The document does not contain details of particular reactor designs nor does it attempt to identify or classify either design basis or beyond design basis accidents. Further, this document is an initial attempt by a small set of subject matter experts to document the safety and licensing characteristics of FHRs for a larger audience. The document is intended to help in setting the safety and licensing research, development, and demonstration path forward. Input from a wider audience, further technical developments, and additional study will be required to develop a consensus position on the safety and licensing characteristics of FHRs. This document begins with a brief overview of the attributes of FHRs and then a general description of their anticipated safety performance. Following this, an overview of the US nuclear power plant approval process is provided that includes both test and power reactors, as well as the role of safety standards in the approval process. The document next describes a General Design Criteria (GDC) - based approach to licensing an FHR and provides an initial draft set of FHR GDCs. The document concludes with a description of a path forward toward developing an FHR safety standard that can support both a test and power reactor licensing process.

  7. Criteria for performance evaluation

    Directory of Open Access Journals (Sweden)

    David J. Weiss

    2009-03-01

    Full Text Available Using a cognitive task (mental calculation and a perceptual-motor task (stylized golf putting, we examined differential proficiency using the CWS index and several other quantitative measures of performance. The CWS index (Weiss and Shanteau, 2003 is a coherence criterion that looks only at internal properties of the data without incorporating an external standard. In Experiment 1, college students (n = 20 carried out 2- and 3-digit addition and multiplication problems under time pressure. In Experiment 2, experienced golfers (n = 12, also college students, putted toward a target from nine different locations. Within each experiment, we analyzed the same responses using different methods. For the arithmetic tasks, accuracy information (mean absolute deviation from the correct answer, MAD using a coherence criterion was available; for golf, accuracy information using a correspondence criterion (mean deviation from the target, also MAD was available. We ranked the performances of the participants according to each measure, then compared the orders using Spearman's rextsubscript{s}. For mental calculation, the CWS order correlated moderately (rextsubscript{s} =.46 with that of MAD. However, a different coherence criterion, degree of model fit, did not correlate with either CWS or accuracy. For putting, the ranking generated by CWS correlated .68 with that generated by MAD. Consensual answers were also available for both experiments, and the rankings they generated correlated highly with those of MAD. The coherence vs. correspondence distinction did not map well onto criteria for performance evaluation.

  8. [BMW diagnostic criteria for IBS].

    Science.gov (United States)

    Matsueda, Kei

    2006-08-01

    Rome I diagnostic criteria for IBS was published in 1992 and it became a global diagnostic criteria. However, the criteria was not practical and somewhat complicated. Moreover, its symptomatic duration was too long (defined as more than 3 months) to be introduced in clinical practice. Therefore, Japanese member of BMW(Bowel Motility Workshop) tried to develop a new diagnostic criteria for IBS and it was established in 1995 by way of the Delphi method. The criteria was named as BMW diagnostic criteria and it was shown below: BMW diagnostic criteria for IBS (1995) At least one month or more of repetitive symptoms of the following 1) and 2) and no evidence of organic disease that likely to explain the symptoms. 1) Existence of abdominal pain, abdominal discomfort or abdominal distension 2) Existence of abnormal bowel movement (diarrhea, constipation) Abnormal bowel movement includes at least one of the below; (1) Abnormal stool frequency (2) Abnormal stool form (lumpy/hard or loose/wartery stool) Moreover, the following test should be performed as a rule to exclude organic diseases. (1) Urinalysis, fecal occult blood testing, CBC, chemistry (2) Barium enema or colonofiberscopic examination The other diagnostic criteria for IBS was also reviewed and their characteristics were compared with BMW diagnostic criteria.

  9. South African medical schools: Current state of selection criteria and ...

    African Journals Online (AJOL)

    uncertainty as to whether the widely accepted view that academic success at high ... Administration, PhD; A St Clair Gibson,1 MB ChB, PhD, MD; M Viljoen,1 BComm, MBA; J E Iputo,2 MB ChB, PhD; M Mammen,2 MSc, ... cognitive ability by testing language, mathematical and reasoning ability. ... Students' financial need,[8].

  10. ACR Appropriateness Criteria Crohn Disease.

    Science.gov (United States)

    Kim, David H; Carucci, Laura R; Baker, Mark E; Cash, Brooks D; Dillman, Jonathan R; Feig, Barry W; Fowler, Kathryn J; Gage, Kenneth L; Noto, Richard B; Smith, Martin P; Yaghmai, Vahid; Yee, Judy; Lalani, Tasneem

    2015-10-01

    Crohn disease is a chronic inflammatory disorder involving the gastrointestinal tract, characterized by episodic flares and times of remission. Underlying structural damage occurs progressively, with recurrent bouts of inflammation. The diagnosis and management of this disease process is dependent on several clinical, laboratory, imaging, endoscopic, and histologic factors. In recent years, with the maturation of CT enterography, and MR enterography, imaging has played an increasingly important role in relation to Crohn Disease. In addition to these specialized examination modalities, ultrasound and routine CT have potential uses. Fluoroscopy, radiography, and nuclear medicine may be less beneficial depending on the clinical scenario. The imaging modality best suited to evaluating this disease may change, depending on the target population, severity of presentation, and specific clinical situation. This document presents seven clinical scenarios (variants) in both the adult and pediatric populations and rates the appropriateness of the available imaging options. They are summarized in a consolidated table, and the underlying rationale and supporting literature are presented in the accompanying narrative. The ACR Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed every three years by a multidisciplinary expert panel. The guideline development and review include an extensive analysis of current medical literature from peer-reviewed journals and the application of a well established consensus methodology (modified Delphi) to rate the appropriateness of imaging and treatment procedures by the panel. In those instances in which evidence is lacking or not definitive, expert opinion may be used to recommend imaging or treatment.

  11. Critical appraisal of the 1977 diagnostic criteria for Minamata disease.

    Science.gov (United States)

    Yorifuji, Takashi; Tsuda, Toshihide; Inoue, Sachiko; Takao, Soshi; Harada, Masazumi; Kawachi, Ichiro

    2013-01-01

    Large-scale food poisoning caused by methylmercury was identified in Minamata, Japan, in the 1950s (Minamata disease). Although the diagnostic criteria for the disease remain current, few studies have been carried out to assess the diagnostic accuracy of the criteria. From a 1971 population-based investigation, data from 2 villages were selected: Minamata (high-exposure area; n = 779) and Ariake (low-exposure area; n = 755). The authors examined the prevalence of neurologic signs characteristic of methylmercury poisoning and the validity of the criteria. A substantial number of residents in the exposed area exhibited neurologic signs even after excluding officially certified patients. Using paresthesia of the extremities as the gold standard of diagnosis, the criteria had a sensitivity of 66%. The current diagnostic criteria as well as the official certification system substantially underestimate the incidence of Minamata disease.

  12. Developing 2 C-compatible investment criteria

    Energy Technology Data Exchange (ETDEWEB)

    Roeser, Frauke [NewClimate - Institute for Climate Policy and Global Sustainability gGmbH, Bonn (Germany); Weischer, Lutz [Germanwatch e.V., Koeln (Germany); Thomae, Jakob [2degrees Investing Initiative, New York, NY (United States); Hoehne, Niklas; Hagemann, Markus; El Alaoui, Alexander; Bals, Christoph; Eckstein, David; Kreft, Soenke; Rosse, Morten

    2015-11-30

    This report studies the development of criteria for assessing the compatibility of financial investments with the international goal to limit global temperature increase to below 2 C above pre-industrial levels. The findings are intended as a starting point and a key input for a longer term process to develop consensus-based 2 C investing criteria. The focus here is placed on investments in projects and physical assets, in particular of development and climate finance organisations. In order to limit global temperature increase to 2 C, global greenhouse gas (GHG) emissions will have to be reduced significantly, eventually to zero, during the course of this century. This requires shifting capital from high to low carbon investments as well as significant capital mobilisation for investments in 2 C-compatible infrastructure. Given the long lifetime of physical assets, and the urgency of decarbonisation over the coming decades, this needs to begin today. Public financial institutions can play a prominent role in contributing to aligning investment flows with the 2 C limit, as well as in closing the current infrastructure investment gap, responding to their explicit or implicit climate mandates and leadership role in the finance sector. The majority of international financial institutions integrate climate considerations into their finance decisions to some degree, and are familiar with different types of criteria, including positive and negative lists, qualitative and quantitative benchmarks, and the use of shadow carbon pricing. However, current approaches do not link to the 2 C limit. 2 C investment criteria are therefore needed to guide investors in this regard. Such criteria may also support other purposes, including an understanding of climate risks and improved reporting and accountability.

  13. New criteria to identify spectrum

    DEFF Research Database (Denmark)

    Jensen, Arne; Krishna, M.

    2005-01-01

    In this paper we give some new criteria for identifying the components of a probability measure, in its Lebesgue decomposition. This enables us to give new criteria to identify spectral types of self-adjoint operators on Hilbert spaces, especially those of interest....

  14. Performance of Complicated Grief Criteria

    NARCIS (Netherlands)

    Smid, Geert E; Boelen, Paul A

    2016-01-01

    To the Editor: We read with interest the article by Cozza et al. on the accuracy of DSM-5 persistent complex bereavement disorder criteria (1). The study suggests that complicated grief criteria are more sensitive in detecting cases with grief-related symptoms than persistent complex bereavement dis

  15. Markovianity criteria for quantum evolution

    Science.gov (United States)

    Chruściński, Dariusz; Kossakowski, Andrzej

    2012-08-01

    We characterize a class of Markovian dynamics using the concept of a divisible dynamical map. Moreover, we provide a family of criteria which can distinguish Markovian and non-Markovian dynamics. These Markovianity criteria are based on a simple observation that Markovian dynamics implies monotonic behaviour of several well-known quantities such as distinguishability of states, fidelity, relative entropy and genuine entanglement measures.

  16. Markovianity criteria for quantum evolution

    CERN Document Server

    Chruściński, Dariusz

    2012-01-01

    We characterize a class of Markovian dynamics using the concept of divisible dynamical map. Moreover we provide a family of criteria which can distinguish Markovian and non-Markovian dynamics. These Markovianity criteria are based on a simple observation that Markovian dynamics implies monotonic behavior of several well known quantities like distinguishability of states, fidelity, relative entropy and genuine entanglement measures.

  17. New Criteria to Identify Spectrum

    Indian Academy of Sciences (India)

    A Jensen; M Krishna

    2005-05-01

    In this paper we give some new criteria for identifying the components of a probability measure, in its Lebesgue decomposition. This enables us to give new criteria to identify spectral types of self-adjoint operators on Hilbert spaces, especially those of interest.

  18. Principles and Criteria for Design

    DEFF Research Database (Denmark)

    Beghin, D.; Cervetto, D.; Hansen, Peter Friis

    1997-01-01

    The mandate of ISSC Committee IV.1 on principles and Criteria for Design is to report on the following:The ongoing concern for quantification of general economic and safety criteria for marine structures and for the development of appropriate principles for rational life cycle design using...

  19. Peer Assessment without Assessment Criteria

    Science.gov (United States)

    Jones, Ian; Alcock, Lara

    2014-01-01

    Peer assessment typically requires students to judge peers' work against assessment criteria. We tested an alternative approach in which students judged pairs of scripts against one another in the absence of assessment criteria. First year mathematics undergraduates (N?=?194) sat a written test on conceptual understanding of multivariable…

  20. MHD-ETF design criteria

    Energy Technology Data Exchange (ETDEWEB)

    Retallick, F.D.

    1978-04-01

    This document establishes criteria to be utilized for the design of a pilot-scale (150 to 300 MW thermal) open cycle, coal-fired MHD/steam plant. Criteria for this Engineering Test Facility (ETF) are presented relative to plant siting, plant engineering and operations, MHD-ETF testing, costing and scheduling.

  1. Mathematics Teachers' Criteria of Dimension

    Science.gov (United States)

    Ural, Alattin

    2014-01-01

    The aim of the study is to determine mathematics teachers' decisions about dimensions of the geometric figures, criteria of dimension and consistency of decision-criteria. The research is a qualitative research and the model applied in the study is descriptive method on the basis of general scanning model. 15 mathematics teachers attended the…

  2. Principles and Criteria for Design

    DEFF Research Database (Denmark)

    Beghin, D.; Cervetto, D.; Hansen, Peter Friis

    1997-01-01

    The mandate of ISSC Committee IV.1 on principles and Criteria for Design is to report on the following:The ongoing concern for quantification of general economic and safety criteria for marine structures and for the development of appropriate principles for rational life cycle design using...

  3. Failure Criteria for Reinforced Materials

    DEFF Research Database (Denmark)

    Rathkjen, Arne

    Failure of materials is often characterized as ductile yielding, brittle fracture, creep rupture, etc., and different criteria given in terms of different parameters have been used to describe different types of failure. Only criteria expressing failure in terms of stress are considered in what...... place until the matrix, the continuous component of the composite, fails. When an isotropic matrix is reinforced as described above, the result is an anisotropic composite material. Even if the material is anisotropic, it usually exhibits a rather high degree of symmetry and such symmetries place...... certain restrictions on the form of the failure criteria for anisotropic materials. In section 2, some failure criteria for homogenous materials are reviewed. Both isotropic and anisotropic materials are described, and in particular the constraints imposed on the criteria from the symmetries orthotropy...

  4. Study for Updated Gout Classification Criteria

    DEFF Research Database (Denmark)

    Taylor, William J; Fransen, Jaap; Jansen, Tim L

    2015-01-01

    OBJECTIVE: To determine which clinical, laboratory, and imaging features most accurately distinguished gout from non-gout. METHODS: We performed a cross-sectional study of consecutive rheumatology clinic patients with ≥1 swollen joint or subcutaneous tophus. Gout was defined by synovial fluid or ...... (MTP1) joint ever involved (multivariate OR 2.30), location of currently tender joints in other foot/ankle (multivariate OR 2.28) or MTP1 joint (multivariate OR 2.82), serum urate level >6 mg/dl (0.36 mmoles/liter; multivariate OR 3.35), ultrasound double contour sign (multivariate OR 7...... been identified for further evaluation for new gout classification criteria. Ultrasound findings and degree of uricemia add discriminating value, and will significantly contribute to more accurate classification criteria....

  5. Prioritizing Project Performance Criteria within Client Perspective

    Directory of Open Access Journals (Sweden)

    Arazi Idrus

    2011-10-01

    Full Text Available Successful performance in a construction project helps to deliver good products to the client. At present, there is no standard approach used by clients to evaluate project performance as project success carries different definitions to different people. Some used the traditional project performance measures of cost, quality and time while others used additional non-traditional measures such as the environment, health and safety, level of technology and contractor planning. The purpose of this study is to identify and rank the actual criteria used by local clients in current practice to measure the performance of a construction project during construction as well as upon completion. The ranking is based on the relative importance of the criteria as perceived by project performance decision makers working for clients’ organizations within the Malaysian construction industry using their accumulated experience and judgment. The objective of this study was investigated through a postal questionnaire which covered a selected sample of the study. Data were analyzed using mean, variance, frequency and severity index analyses. The results of this paper show that Quality of finished project, Construction cost and Construction time were the three most important criteria considered crucial by the respondents for evaluating project performance from current practice in Malaysia. The paper provides supportive practical solution for project performance decision makers working for clients’ organizations within the Malaysian construction industry to enhance and improve their practices in measuring their clients’ project performance so that their clients would enjoy higher satisfaction levels from their projects. More so, the paper would serve as a guide to contractors by helping them to understand that Quality of finished project, Construction cost and Construction time are the criteria given high priority by clients in measuring the performance of a

  6. Floorball game skills (evaluation criteria)

    OpenAIRE

    Chlumský, Marek

    2013-01-01

    Title: Playing skills in floorball (evaluation criteria). Target: To create a list of playing skills which an ideal player should demonstrate. Find and verify the evaluation criteria of these skills and inspire trainers to develop these skills in the best way. Methods: Informal interviews, individually structured interviews, analysis and verification of data, pilot testing. Results: Defined playing skills in floorball, developed scale of values of floorball playing skills, creation of exercis...

  7. Reliability criteria for voltage stability

    Energy Technology Data Exchange (ETDEWEB)

    Taylor, Carson W.; Silverstein, Brian L. [Bonneville Power Administration, Portland, OR (United States)

    1994-12-31

    In face of costs pressures, there is need to allocate scare resources more effectively in order to achieve voltage stability. This naturally leads to development of probabilistic criteria and notions of rick management. In this paper it is presented a discussion about criteria for long term voltage stability limited to the case in which the time frames are topically several minutes. (author) 14 refs., 1 fig.

  8. Determination of criteria weights in solving multi-criteria problems

    Science.gov (United States)

    Kasim, Maznah Mat

    2014-12-01

    A multi-criteria (MC) problem comprises of units to be analyzed under a set of evaluation criteria. Solving a MC problem is basically the process of finding the overall performance or overall quality of the units of analysis by using certain aggregation method. Based on these overall measures of each unit, a decision can be made whether to sort them, to select the best or to group them according to certain ranges. Prior to solving the MC problems, the weights of the related criteria have to be determined with the assumption that the weights represent the degree of importance or the degree of contribution towards the overall performance of the units. This paper presents two main approaches which are called as subjective and objective approaches, where the first one involves evaluator(s) while the latter approach depends on the intrinsic information contained in each criterion. The subjective and objective weights are defined if the criteria are assumed to be independent with each other, but if they are dependent, there is another type of weight, which is called as monotone measure weight or compound weights which represent degree of interaction among the criteria. The measure of individual weights or compound weights must be addressed in solving multi-criteria problems so that the solutions are more reliable since in the real world, evaluation criteria always come with different degree of importance or are dependent with each other. As the real MC problems have their own uniqueness, it is up to the decision maker(s) to decide which type of weights and which method are the most applicable ones for the problem under study.

  9. A PROPOSED METHODOLOGY FOR STRAIN BASED FAILURE CRITERIA

    Energy Technology Data Exchange (ETDEWEB)

    Wu, T

    2008-05-01

    This paper proposes an alternative methodology to determine the failure criteria for use in dynamic simulations of radioactive material shipping packages in the events of hypothetical accident conditions. The current stress failure criteria defined in the Nuclear Regulatory Guide 7.6 [1] and the ASME Code, Section III, Appendix F [2] for Level D Service Loads are based on the ultimate strength of uniaxial tensile test specimen rather than on the material fracture in the state of multi-axial stresses. On the other hand, the proposed strain-based failure criteria are directly related to the material failure mechanisms in multi-axial stresses. In addition, unlike the stress-based criteria, the strain-based failure criteria are applicable to the evaluation of cumulative damages caused by the sequential loads in the hypothetical accident events as required by the Nuclear Regulatory Guide 7.8 [4].

  10. Design and performance criteria for medical electron accelerators

    Science.gov (United States)

    Nunan, Craig S.

    1985-05-01

    A brief comparison is made of the design and performance of early and modern isocentric microwave linear accelerators for radiotherapy. Generally accepted criteria for the design of current machines are presented, along with a rationale for their selection. The current development of international standards for safety and performance of medical electron accelerators is reviewed.

  11. Understanding seismic design criteria for Japanese Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Park, Y.J.; Hofmayer, C.H. [Brookhaven National Lab., Upton, NY (United States); Costello, J.F. [Nuclear Regulatory Commission, Washington, DC (United States)

    1995-04-01

    This paper summarizes the results of recent survey studies on the seismic design practice for nuclear power plants in Japan. The seismic design codes and standards for both nuclear as well as non-nuclear structures have been reviewed and summarized. Some key documents for understanding Japanese seismic design criteria are also listed with brief descriptions. The paper highlights the design criteria to determine the seismic demand and component capacity in comparison with U.S. criteria, the background studies which have led to the current Japanese design criteria, and a survey of current research activities. More detailed technical descriptions are presented on the development of Japanese shear wall equations, design requirements for containment structures, and ductility requirements.

  12. Social Advertising Quality: Assessment Criteria

    Directory of Open Access Journals (Sweden)

    S. B. Kalmykov

    2017-01-01

    Full Text Available Purpose: the The purpose of the publication is development of existing criterial assessment in social advertising sphere. The next objectives are provided for its achievement: to establish research methodology, to develop the author’s version of necessary notional apparatus and conceptual generalization, to determine the elements of social advertising quality, to establish the factors of its quality, to conduct the systematization of existing criteria and measuring instruments of quality assessment, to form new criteria of social advertising quality, to apply received results for development of criterial assessment to determine the further research perspectives. Methods: the methodology of research of management of social advertising interaction with target audience, which has dynamic procedural character with use of sociological knowledge multivariate paradigmatic status, has been proposed. Results: the primary received results: the multivariate paradigmatic research basis with use of works of famous domestic and foreign scientists in sociology, qualimetry and management spheres; the definitions of social advertising, its quality, sociological quality provision system, target audience behavior model during social advertising interaction are offered; the quality factors with three groups by level of effect on consumer are established; the systematization of existing quality and its measure instruments assessment criteria by detected social advertising quality elements are conducted; the two new criteria and its management quality assessment measuring instruments in social advertising sphere are developed; the one of the common groups of production quality criteria – adaptability with considering of new management quality criteria and conducted systematization of existing social advertising creative quality assessment criteria development; the perspective of further perfection of quality criterial assessment based on social advertising

  13. Optimum Currency Area Criteria in the Greece

    Directory of Open Access Journals (Sweden)

    Milovan Rankov

    2013-08-01

    Full Text Available Creation of a monetary union in any region, regardless of the structure and level of development among countries, carries along certain costs and benefits. This paper explains Mundell’s concept of Optimum Currency Area and criteria that are needed to achieve it. Viewed through the prism of these criteria the EMU is currently far from achieving the OCA confirming the current crisis in Greece and other PIIGS countries. The example of Greece and shortcomings that contributed to its current crisis represents the biggest cost and a break-even point for the future of the monetary union. However, it is encouraging that Greece is not alone in its problems, since various funds for help have been established in a relatively short period of time. The reason for this is certainly a huge cost if any country should leave the union and the spillover effect that it would cause. Certainly serious transformations can be expected and the result should be a stronger union with better control from supra-national level.

  14. Ferrocyanide Safety Program: Safety criteria for ferrocyanide watch list tanks

    Energy Technology Data Exchange (ETDEWEB)

    Postma, A.K.; Meacham, J.E.; Barney, G.S. [and others

    1994-01-01

    This report provides a technical basis for closing the ferrocyanide Unreviewed Safety Question (USQ) at the Hanford Site. Three work efforts were performed in developing this technical basis. The efforts described herein are: 1. The formulation of criteria for ranking the relative safety of waste in each ferrocyanide tank. 2. The current classification of tanks into safety categories by comparing available information on tank contents with the safety criteria; 3. The identification of additional information required to resolve the ferrocyanide safety issue.

  15. Diagnostic criteria for vascular cognitive disorders: a VASCOG statement

    Science.gov (United States)

    Sachdev, Perminder; Kalaria, Raj; O’Brien, John; Skoog, Ingmar; Alladi, Suvarna; Black, Sandra E; Blacker, Deborah; Blazer, Dan; Chen, Christopher; Chui, Helena; Ganguli, Mary; Jellinger, Kurt; Jeste, Dilip V.; Pasquier, Florence; Paulsen, Jane; Prins, Niels; Rockwood, Kenneth; Roman, Gustavo; Scheltens, Philip

    2014-01-01

    Background Several sets of diagnostic criteria have been published for vascular dementia (VaD) since the 1960s. The continuing ambiguity in VaD definition warrants a critical re-examination. Methods Participants at a special symposium of the International Society for Vascular Behavioral and Cognitive Disorders (VASCOG) in 2009 critiqued the current criteria. They drafted a proposal for a new set of criteria, later reviewed through multiple drafts by the group, including additional experts and the members of the Neurocognitive Disorders Work Group of the DSM-5 Task Force. Results Cognitive disorders of vascular etiology are a heterogeneous group of disorders with diverse pathologies and clinical manifestations, discussed broadly under the rubric of vascular cognitive disorders (VCD). The continuum of vascular cognitive impairment is recognized by the categories of Mild Vascular Cognitive Disorder, and Vascular Dementia or Major Vascular Cognitive Disorder. Diagnostic thresholds are defined. Clinical and neuroimaging criteria are proposed for establishing vascular etiology. Subtypes of VCD are described, and the frequent co-occurrence of Alzheimer’s disease pathology emphasized. Conclusions The proposed criteria for VCD provide a coherent approach to the diagnosis of this diverse group of disorders, with a view to stimulating clinical and pathological validation studies. These criteria can be harmonized with the DSM-5 criteria such that an international consensus on the criteria for VCD may be achieved. PMID:24632990

  16. ASAS classification criteria for axial spondyloarthritis: time to modify.

    Science.gov (United States)

    Akkoc, Nurullah; Khan, Muhammad A

    2016-06-01

    The relationship between ankylosing spondylitis and the recently proposed entity called axial spondyloarthritis with its radiographic and non-radiographic forms that have been defined by the Assessment of Spondyloarthritis International Society (ASAS) criteria for axial spondyloarthritis (axSpA), is currently being debated. The Food and Drug Agency (FDA) had criticized the ASAS criteria and the studies which used these criteria to enroll patients in a clinical trial of certolizumab and adalimumab for the treatment of non-radiographic axial spondyloarthritis. The primary aim of classification criteria is to create homogenous patient populations for basic and clinical research. But the multi-arm construct of the ASAS criteria is a potential source of heterogeneity reducing their utility. Criteria sets should be regarded as dynamic concepts open to modifications or updates as our knowledge advances. We provide evidence to conclude that it is time to modify the ASAS Criteria for axSpA, and we propose some of the steps that can be taken to start moving forward in improving the validity of these criteria.

  17. Evolving diagnostic criteria for multiple myeloma.

    Science.gov (United States)

    Rajkumar, S Vincent

    2015-01-01

    Multiple myeloma (MM) is a plasma cell malignancy historically defined by the presence of end-organ damage, specifically, hypercalcemia, renal failure, anemia, and bone lesions (CRAB features) that can be attributed to the neoplastic process. In 2014, the International Myeloma Working Group (IMWG) updated the diagnostic criteria for MM to add specific biomarkers that can be used to make the diagnosis of the disease in patients who did not have CRAB features. In addition, the update allows modern imaging methods including computed tomography (CT) and positron emission tomography-CT to diagnose MM bone disease. These changes enable early diagnosis, and allow the initiation of effective therapy to prevent the development of end-organ damage in patients who are at the highest risk. This article reviews these and several other clarifications and revisions that were made to the diagnostic criteria for MM and related disorders. The updated disease definition for MM also automatically resulted in a revision to the diagnostic criteria for the asymptomatic phase of the disease termed smoldering MM (SMM). Thus the current diagnosis and risk-stratification of SMM is also reviewed in this article. Using specific prognostic factors, it is possible to identify a subset of patients with SMM who have a risk of progression to MM of 25% per year (high-risk SMM). An approach to the management of patients with low- and high-risk SMM is discussed.

  18. Acceptance criteria for urban dispersion model evaluation

    Science.gov (United States)

    Hanna, Steven; Chang, Joseph

    2012-05-01

    The authors suggested acceptance criteria for rural dispersion models' performance measures in this journal in 2004. The current paper suggests modified values of acceptance criteria for urban applications and tests them with tracer data from four urban field experiments. For the arc-maximum concentrations, the fractional bias should have a magnitude 0.3. For all data paired in space, for which a threshold concentration must always be defined, the normalized absolute difference should be SCIPUFF dispersion model with the urban canopy option and the urban dispersion model (UDM) option. In each set of evaluations, three or four likely options are tested for meteorological inputs (e.g., a local building top wind speed, the closest National Weather Service airport observations, or outputs from numerical weather prediction models). It is found that, due to large natural variability in the urban data, there is not a large difference between the performance measures for the two model options and the three or four meteorological input options. The more detailed UDM and the state-of-the-art numerical weather models do provide a slight improvement over the other options. The proposed urban dispersion model acceptance criteria are satisfied at over half of the field experiments.

  19. Diagnostic criteria for autoimmune pancreatitis in Japan

    Institute of Scientific and Technical Information of China (English)

    Terumi Kamisawa; Kazuichi Okazaki; Shigeyuki Kawa

    2008-01-01

    Autoimmune pancreatitis (AIP) is a particular type of pancreatitis of presumed autoimmune etiology.Currently, AIP should be diagnosed based on combination of clinical, serological, morphological,and hisLopathological features. When diagnosing AlP,it is most Jmportant to differentiate it from pancreatic cancer. DJagnostic criteria for AIP, proposed by the Japan Pancreas Society in 2002 first in the world,were revised in 2006. The criteria are based on the minimum consensus of AIP and aim to avoid misdiagnosing pancreatic cancer as far as possible,but not for screening AIP. The criteria consist of the following radiological, serological, and histopathological items: (1) radiological imaging showing narrowing of the main pancreatic duct and enlargement of the pancreas, which are characteristic of the disease; (2)laboratory data showing abnormally elevated levels of serum γ-globulin, IgG or IgG4, or the presence of autoantibodies; (3) histopathological examJnation of the pancreas demonstrating marked fibrosis and prominent infiltration of lymphocytes and plasma cells, which is called lymphoplasmacytic sclerosing pancreatitis (LPSP). For a diagnosis of AIP, criterion 1 must be present, together with criterion 2 and/or criterion 3. However, it is necessary to exclude malignant diseases such as pancreatic or biliary cancer.

  20. Developing consensus criteria for sarcopenia: an update.

    Science.gov (United States)

    McLean, Robert R; Kiel, Douglas P

    2015-04-01

    Sarcopenia, the age-related loss of muscle mass and strength, is a major cause of impaired physical function, which contributes to mobility disability, falls and hospitalizations in older adults. Lower muscle mass and strength are also associated with lower bone mineral density and greater risk for osteoporotic fractures. Thus, identification of sarcopenia could be important for fracture prevention as it may help improve fracture risk assessment, and muscle mass and strength can be improved with exercise, even among the frailest older adults. Unfortunately, there are no consensus diagnostic criteria for sarcopenia. Consequently there is no guidance to help clinicians identify older adults with clinically meaningful low muscle mass or weakness. Further, development of novel sarcopenia therapies is hindered not only due to the difficulty in identifying participants for clinical trials, and but also because there are no validated, clinically appropriate endpoints for assessment of treatment efficacy. There is currently a major push to establish a consensus definition of sarcopenia, and recent work holds promise that this goal may be within reach. This article discusses the evolution of the definition of sarcopenia, and focuses on the latest recommended diagnostic criteria proposed by the Foundation for the National Institutes of Health (FNIH) Sarcopenia Project. While these empirically-based cut-points for clinically important low muscle mass and weakness are a significant step forward for the sarcopenia field, important questions remain to be answered before consensus diagnostic criteria can be definitively established. Ongoing work to refine sarcopenia criteria will further advance the field and bring this important contributor to falls, fractures and disability into the mainstream of clinical care and ultimately lead to better quality of life with aging. © 2015 American Society for Bone and Mineral Research.

  1. Radiation design criteria handbook. [design criteria for electronic parts applications

    Science.gov (United States)

    Stanley, A. G.; Martin, K. E.; Douglas, S.

    1976-01-01

    Radiation design criteria for electronic parts applications in space environments are provided. The data were compiled from the Mariner/Jupiter Saturn 1977 electronic parts radiation test program. Radiation sensitive device types were exposed to radiation environments compatible with the MJS'77 requirements under suitable bias conditions. A total of 189 integrated circuits, transistors, and other semiconductor device types were tested.

  2. Toward new criteria for systemic lupus erythematosus-a standpoint.

    Science.gov (United States)

    Aringer, M; Dörner, T; Leuchten, N; Johnson, S R

    2016-07-01

    While clearly different in their aims and means, classification and diagnosis both try to accurately label the disease patients are suffering from. For systemic lupus erythematosus (SLE), this is complicated by the multi-organ nature of the disease and by our incomplete understanding of its pathophysiology. Hallmarks of SLE are the presence of antinuclear antibodies (ANA), and multiple immune-mediated organ symptoms that are largely independent. In an attempt to overcome limitations of the current sets of SLE classification criteria, a new four-phase approach is being developed, which is jointly supported by the European League Against Rheumatism (EULAR) and the American College of Rheumatology (ACR). This review attempts to delineate the performance of the current sets of criteria, the reasons for the decision for classification, and not diagnostic, criteria, and to provide a background of the current approach taken.

  3. Technical guidance for siting criteria development

    Energy Technology Data Exchange (ETDEWEB)

    Aldrich, D.C.; Sprung, J.L.; Alpert, D.J.; Diegert, K.; Ostmeyer, R.M.; Ritchie, L.T.; Strip, D.R.; Johnson, J.D.; Hansen, K.; Robinson, J.

    1982-12-01

    Technical guidance to support the formulation and comparison of possible siting criteria for nuclear power plants has been developed in four areas: (1) consequences of hypothetical severe nuclear-power-plant accidents, (2) characteristics of population distributions about current reactor sites, (3) site availability within the continental United States, and (4) socioeconomic impacts of reactor siting. The impact on consequences of source-term magnitude, meteorology, population distribution, and emergency response have been analyzed. Population distributions about current sites were analyzed to identify statistical characteristics, time trends, and regional differences. A site-availability data bank was constructed for the continential United States. The data bank contains information about population densities, seismicity, topography, water availability, and land-use restrictions. Finally, the socioeconomic impacts of rural-industrialization projects, energy boomtowns, and nuclear power plants were examined to determine their nature, magnitude, and dependence on site demography and remoteness.

  4. Profiles, Criteria and the GCSE.

    Science.gov (United States)

    Fairbrother, R. W.

    1985-01-01

    Several changes in assessment of students in Great Britain are being considered, including establishing a common system of examining at 16-plus and moving toward specifying criteria for the award of grades. Issues related to these trends (including the demise of the General Certificate of Secondary Education--GCSE) are examined. (JN)

  5. Aquatic Plant Water Quality Criteria

    Science.gov (United States)

    The USEPA, as stated in the Clean Water Act, is tasked with developing numerical Aquatic Life Critiera for various pollutants found in the waters of the United States. These criteria serve as guidance for States and Tribes to use in developing their water quality standards. The G...

  6. Aversive Stimulation -- Criteria for Application.

    Science.gov (United States)

    O'Donnell, Patrick A.; Ohlson, Glenn A.

    Criteria for applying aversive stimulation with severely handicapped children are examined, and practical and ethical issues are considered. Factors seen to influence punishment outcomes include timing, intensity, and schedule of reinforcement. Suggested is the need for further research on the comparative effectiveness of positive and negative…

  7. Platinum-induced ototoxicity: a review of prevailing ototoxicity criteria.

    Science.gov (United States)

    Waissbluth, Sofia; Peleva, Emilia; Daniel, Sam J

    2017-03-01

    The antineoplastic agent's cisplatin and carboplatin are widely used as they are highly effective. Unfortunately, ototoxicity is a frequently encountered side effect of platinum-based chemotherapy. Clinically, patients generally develop a progressive, bilateral, and irreversible sensorineural hearing loss. With rising cancer survival rates, a greater proportion of patients are living with the side effects of their chemotherapy treatments. Consequently, the quality of life of cancer survivors has now become a major concern for clinicians. Various classification systems are currently available to grade side effects and provide a guideline for subsequent treatments. An extensive review of the literature revealed that a variety of criteria are used worldwide for grading platinum-induced hearing loss in children and adults, including the National Cancer Institute criteria, Brock's grading system, the American Speech-Hearing-Language Association criteria, the World Health Organization criteria, the Pediatric Oncology Group criteria, and the Muenster classification. Less commonly used criteria include the Chang classification, the Functional Hearing Loss scale, the HIT system (German Hirntumor study grading system), and most recently, the International Society of Pediatric Oncology Boston ototoxicity grading scale. The objective of this review is to evaluate the commonly used ototoxicity criteria and discuss their benefits and limitations.

  8. Science and pseudoscience in communication disorders: criteria and applications.

    Science.gov (United States)

    Finn, Patrick; Bothe, Anne K; Bramlett, Robin E

    2005-08-01

    The purpose of this tutorial is to describe 10 criteria that may help clinicians distinguish between scientific and pseudoscientific treatment claims. The criteria are illustrated, first for considering whether to use a newly developed treatment and second for attempting to understand arguments about controversial treatments. Pseudoscience refers to claims that appear to be based on the scientific method but are not. Ten criteria for distinguishing between scientific and pseudoscientific treatment claims are described. These criteria are illustrated by using them to assess a current treatment for stuttering, the SpeechEasy device. The authors read the available literature about the device and developed a consensus set of decisions about the 10 criteria. To minimize any bias, a second set of independent judges evaluated a sample of the same literature. The criteria are also illustrated by using them to assess controversies surrounding 2 treatment approaches: Fast ForWord and facilitated communication. Clinicians are increasingly being held responsible for the evidence base that supports their practice. The power of these 10 criteria lies in their ability to help clinicians focus their attention on the credibility of that base and to guide their decisions for recommending or using a treatment.

  9. A Comparison of the Green Building’s Criteria

    Directory of Open Access Journals (Sweden)

    Bahaudin A.Y.

    2014-01-01

    Full Text Available Designers and clients alike are now emphasising on how to make their buildings green. Currently a lot of green councils worldwide are dealing with innovative ways to implement energy efficient new buildings. They have adopted various criteria and rating systems in an endeavour to classify buildings that contribute to environment sustainability, efficiency and users health. The aim of the paper is to present an overview of the criteria adopted by selected green building councils. This paper discusses five of the rating systems available in terms of their similarities and differences and proposes a new framework based on the project life cycle for the development of the green building criteria. Criteria during the construction phase of the building is certainly lacking such as pollution control in terms of CO2 emission, dust, and other pollutants.

  10. Normality Criteria of Meromorphic Functions

    Institute of Scientific and Technical Information of China (English)

    Wang Qiong; Yuan Wen-jun; Chen Wei; Tian Hong-gen

    2016-01-01

    In this paper, we consider normality criteria for a family of meromorphic functions concerning shared values. Let F be a family of meromorphic functions defined in a domain D, m, n, k and d be four positive integers satisfying m≥n+2 and d≥ k+1m−n−1 , and a(̸=0), b be two finite constants. Suppose that every f ∈F has all its zeros and poles of multiplicity at least k and d, respectively. If (fn)(k)−afm and (gn)(k)−agm share the value b for every pair of functions (f, g) of F, then F is normal in D. Our results improve the related theorems of Schwick (Schwick W. Normality criteria for families of meromorphic function. J. Anal. Math., 1989, 52:241–289), Li and Gu (Li Y T, Gu Y X. On normal families of meromorphic functions. J. Math. Anal. Appl., 2009, 354: 421–425).

  11. Sustainability Criteria for Contingency Bases

    Science.gov (United States)

    2014-09-01

    Figure 29. Recreation facilities, gym , PX, and social gathering spots co-located. ERDC/CERL TR-14-20 38 Improve site accessibility, safety, and...hydrology, vegetation, human health and well-being and materials selection in order to improve and regenerate the ecosystem. SITES has useful...support areas as close as possible to common use areas (DFAC, gym , ballfields ). Read criteria and apply if possible. IMPROVE SITE ACCESSIBILITY

  12. Repository operational criteria comparative analysis

    Energy Technology Data Exchange (ETDEWEB)

    Hageman, J.P.; Chowdhury, A.H. [Southwest Research Inst., San Antonio, TX (United States). Center for Nuclear Waste Regulatory Analyses

    1994-06-01

    The objective of the ``Repository Operational Criteria (ROC) Feasibility Studies`` (or ROC task) was to conduct comprehensive and integrated analyses of repository design, construction, and operations criteria in 10 CFR Part 60 regulations considering the interfaces among the components of the regulations and impacts of any potential changes to those regulations. The ROC task addresses regulatory criteria and uncertainties related to the preclosure aspects of the geologic repository. Those parts of 10 CFR Part 60 that require routine guidance or minor changes to the rule were addressed in Hageman and Chowdhury, 1992. The ROC task shows a possible need for further regulatory clarity, by major changes to the rule, related to the design bases and siting of a geologic repository operations area and radiological emergency planning in order to assure defense-in-depth. The analyses, presented in this report, resulted in the development and refinement of regulatory concepts and their supporting rationale for recommendations for potential major changes to 10 CFR Pan 0 regulations.

  13. How Turkey Meets MPOWER Criteria?

    Directory of Open Access Journals (Sweden)

    Nazmi Bilir

    2013-02-01

    Full Text Available In 2003 World Health Assembly adopted an international treaty on tobacco control; FCTC, Framework Convention on Tobacco Control. Five year later World Health Organization (WHO declared the six effective approach for tobacco control, under the name of MPOWER. In the following years, WHO evaluated the level of implementation of MPOWER criteria in the countries. In this article, how Turkey implemented these six criteria will be discussed. Monitor tobacco use and prevention policies: Monitoring of tobacco use prevalence has been successfully monitored in Turkey through Global Adult Tobacco Survey, Global Youth Tobacco Survey and Health Professionals Tobacco Use Survey. Nevertheless, monitoring of tobacco industry activities was not successfully implemented. Protect people from tobacco smoke: Smoking was banned in most of the indoor public places in Turkey since 1996, and Turkey became a complete smoke-free country by the exposion of smoke-free places including the hospitality workplaces in 2008. Offer help to quit tobacco use: Although smoking cessation services has been a bit late in Turkey, availability of smoking cessation drugs and the establishment of free quitline services made Turkey successful in this regard. Warn about the dangers of tobacco: Since 1996, all TV channels have a duty of broadcasting programs on harms of tobacco use, not less than 90 minutes in a month and it has been implemented successfully. Additionally written messages indicating harms of tobacco has been printed on the packs since 1988 and pictures was added in 2010. But since the average surface area covered by the messages in less than 50% of the total surface of the pack, Turkey was not regarded as to meet the requirement. Enforce bans on tobacco advertising, promotion and sponsorship: All kinds of tobacco advertisement and promotion was banned by the Law in 1996. But the tobacco products was not in closed boxes at the sales points. Turkey was not found as successful

  14. Expanding the taxonomy of the diagnostic criteria for temporomandibular disorders

    NARCIS (Netherlands)

    Peck, C.C.; Goulet, J-P; Lobbezoo, F.; Schiffman, E.L.; Alstergren, P.; Anderson, G.C.; De Leeuw, R.; Jensen, R.; Michelotti, A.; Ohrbach, R.; Petersson, A.; List, T.

    2014-01-01

    There is a need to expand the current temporomandibular disorders' (TMDs) classification to include less common but clinically important disorders. The immediate aim was to develop a consensus-based classification system and associated diagnostic criteria that have clinical and research utility for

  15. 22 CFR 61.3 - Certification and authentication criteria.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Certification and authentication criteria. 61.3 Section 61.3 Foreign Relations DEPARTMENT OF STATE PUBLIC DIPLOMACY AND EXCHANGES WORLD-WIDE FREE FLOW OF... timely current events (newsreels, newscasts, or other forms of “spot” news). (6) Stimulates the use of a...

  16. 78 FR 69324 - Revised Medical Criteria for Evaluating Hematological Disorders

    Science.gov (United States)

    2013-11-19

    ... the functional criteria in 7.18? 7.00H How do we consider your symptoms, including your pain, severe... term ``major visceral episodes'' in current section 7.00C. We also specify that the hospitalizations do.... Proposed section 7.00H--How do we consider your symptoms, including your pain severe fatigue, and malaise...

  17. DISPOSABLE CANISTER WASTE ACCEPTANCE CRITERIA

    Energy Technology Data Exchange (ETDEWEB)

    R.J. Garrett

    2001-07-30

    The purpose of this calculation is to provide the bases for defining the preclosure limits on radioactive material releases from radioactive waste forms to be received in disposable canisters at the Monitored Geologic Repository (MGR) at Yucca Mountain. Specifically, this calculation will provide the basis for criteria to be included in a forthcoming revision of the Waste Acceptance System Requirements Document (WASRD) that limits releases in terms of non-isotope-specific canister release dose-equivalent source terms. These criteria will be developed for the Department of Energy spent nuclear fuel (DSNF) standard canister, the Multicanister Overpack (MCO), the naval spent fuel canister, the High-Level Waste (HLW) canister, the plutonium can-in-canister, and the large Multipurpose Canister (MPC). The shippers of such canisters will be required to demonstrate that they meet these criteria before the canisters are accepted at the MGR. The Quality Assurance program is applicable to this calculation. The work reported in this document is part of the analysis of DSNF and is performed using procedure AP-3.124, Calculations. The work done for this analysis was evaluated according to procedure QAP-2-0, Control of Activities, which has been superseded by AP-2.21Q, Quality Determinations and Planning for Scientific, Engineering, and Regulatory Compliance Activities. This evaluation determined that such activities are subject to the requirements of DOE/RW/0333P, Quality Assurance Requirements and Description (DOE 2000). This work is also prepared in accordance with the development plan titled Design Basis Event Analyses on DOE SNF and Plutonium Can-In-Canister Waste Forms (CRWMS M&O 1999a) and Technical Work Plan For: Department of Energy Spent Nuclear Fuel Work Packages (CRWMS M&O 2000d). This calculation contains no electronic data applicable to any electronic data management system.

  18. Review of constitutive models and failure criteria for concrete

    Energy Technology Data Exchange (ETDEWEB)

    Seo, Jeong Moon; Choun, Young Sun [Korea Atomic Energy Research Institute, Taejeon (Korea)

    2000-03-01

    The general behavior, constitutive models, and failure criteria of concrete are reviewed. The current constitutive models for concrete cannot satisfy all of mechanical behavior of concrete. Among several constitutive models, damage models are recommended to describe properly the structural behavior of concrete containment buildings, because failure modes and post-failure behavior are important in containment buildings. A constitutive model which can describe the concrete behavior in tension is required because the containment buildings will reach failure state due to ultimate internal pressure. Therefore, a thorough study on the behavior and models under tension stress state in concrete and reinforced concrete has to be performed. There are two types of failure criteria in containment buildings: structural failure criteria and leakage failure criteria. For reinforced or prestressed concrete containment buildings, concrete cracking does not mean the structural failure of containment building because the reinforcement or post-tensioning system is able to resist tensile stress up to yield stress. Therefore leakage failure criteria will be prior to structural failure criteria, and a strain failure criterion for concrete has to be established. 120 refs., 59 figs., 1 tabs. (Author)

  19. Expanding the taxonomy of the diagnostic criteria for temporomandibular disorders.

    Science.gov (United States)

    Peck, C C; Goulet, J-P; Lobbezoo, F; Schiffman, E L; Alstergren, P; Anderson, G C; de Leeuw, R; Jensen, R; Michelotti, A; Ohrbach, R; Petersson, A; List, T

    2014-01-01

    There is a need to expand the current temporomandibular disorders' (TMDs) classification to include less common but clinically important disorders. The immediate aim was to develop a consensus-based classification system and associated diagnostic criteria that have clinical and research utility for less common TMDs. The long-term aim was to establish a foundation, vis-à-vis this classification system, that will stimulate data collection, validity testing and further criteria refinement. A working group [members of the International RDC/TMD Consortium Network of the International Association for Dental Research (IADR), members of the Orofacial Pain Special Interest Group (SIG) of the International Association for the Study of Pain (IASP), and members from other professional societies] reviewed disorders for inclusion based on clinical significance, the availability of plausible diagnostic criteria and the ability to operationalise and study the criteria. The disorders were derived from the literature when possible and based on expert opinion as necessary. The expanded TMDs taxonomy was presented for feedback at international meetings. Of 56 disorders considered, 37 were included in the expanded taxonomy and were placed into the following four categories: temporomandibular joint disorders, masticatory muscle disorders, headache disorders and disorders affecting associated structures. Those excluded were extremely uncommon, lacking operationalised diagnostic criteria, not clearly related to TMDs, or not sufficiently distinct from disorders already included within the taxonomy. The expanded TMDs taxonomy offers an integrated approach to clinical diagnosis and provides a framework for further research to operationalise and test the proposed taxonomy and diagnostic criteria.

  20. RANKING OF MANUFACTURING SYSTEM CRITERIA

    Directory of Open Access Journals (Sweden)

    SHARFUDDIN AHMED KHAN

    2012-06-01

    Full Text Available A high-quality manufacturing system should be capable to meet the company goals. Moreover, it is essential for any organization that its manufacturing system should be aligned with company’s strategy. There is always a potential for improvement in components of manufacturing systems but it is also essential to identify theparticular areas of the components that need improvement. In this paper, we have discussed the most appropriate criterion for good manufacturing systems with the help of a survey that indentified the importance of seven different criteria according to the experts experience and we ranked them accordingly.

  1. Separability criteria for genuine multiparticle entanglement

    NARCIS (Netherlands)

    Guehne, O.; Seevinck, M.P.

    2010-01-01

    We present a method to derive separability criteria for different classes of multiparticle entanglement, especially genuine multiparticle entanglement. The resulting criteria are necessary and sufficient for certain families of states. This, for example, completely solves the problem of classifying

  2. Diagnostic criteria in proliferative verrucous leukoplakia: Evaluation

    Science.gov (United States)

    García-Chías, Begoña; Casado-De La Cruz, Laura; Esparza-Gómez, Germán C.

    2014-01-01

    Objectives: to evaluate the ability of the diagnostic criteria proposed by Cerero et al in 2010 to perform an early diagnose in patients with proliferative verrucous leukoplakia. Study Design: retrospective study with patients diagnosed with leukoplakia at Oral Medicine Service at Oral Medicine and Surgery Department at Dentistry Faculty at Universidad Complutense of Madrid. Results: the criteria were applied in 116 patients, turning positive in 40 cases. Out of these, 24 (60%) had been previously diagnosed with PVL. Most frequent criteria were major criteria A and E, concerning lesion’s site and histopathology, and minor criteria b and c, concerning sex and smoking habit. Conclusions: diagnostic criteria developed by Cerero et al can be a useful tool for an early diagnose of PVL, as in 60% of the cases, the criteria would have allowed to make an early diagnose of the disease. Key words:Proliferative verrucous leukoplakia, criteria, diagnose, early. PMID:24608210

  3. Criteria for onsite transfers of radioactive material

    Energy Technology Data Exchange (ETDEWEB)

    Opperman, E.K.; Jackson, E.J.; Eggers, A.G.

    1992-12-31

    A general description of the requirements for making onsite transfers of radioactive material is provided in Chapter 2, along with the required sequencey of activities. Various criteria for package use are identified in Chapters 3-13. These criteria provide protection against undue radiation exposure. Package shielding, containment, and surface contamination requirements are established. Criteria for providing criticality safety are enumerated in Chapter 6. Criteria for providing hazards information are established in Chapter 13. A glossary is provided.

  4. Developing criteria for pediatric/adolescent bariatric surgery programs.

    Science.gov (United States)

    Michalsky, Marc; Kramer, Robert E; Fullmer, Michelle A; Polfuss, Michele; Porter, Renee; Ward-Begnoche, Wendy; Getzoff, Elizabeth A; Dreyer, Meredith; Stolzman, Stacy; Reichard, Kirk W

    2011-09-01

    The prevalence of morbid obesity in adolescents is rising at an alarming rate. Comorbidities known to predispose to cardiovascular disease are increasingly being diagnosed in these children. Bariatric surgery has become an acceptable treatment alternative for morbidly obese adults, and criteria have been developed to establish center-of-excellence designation for adult bariatric surgery programs. Evidence suggests that bariatric surgical procedures are being performed with increasing numbers in adolescents. We have examined and compiled the current expert recommendations for guidelines and criteria that are needed to deliver safe and effective bariatric surgical care to adolescents.

  5. Detection methods and performance criteria for genetically modified organisms.

    Science.gov (United States)

    Bertheau, Yves; Diolez, Annick; Kobilinsky, André; Magin, Kimberly

    2002-01-01

    Detection methods for genetically modified organisms (GMOs) are necessary for many applications, from seed purity assessment to compliance of food labeling in several countries. Numerous analytical methods are currently used or under development to support these needs. The currently used methods are bioassays and protein- and DNA-based detection protocols. To avoid discrepancy of results between such largely different methods and, for instance, the potential resulting legal actions, compatibility of the methods is urgently needed. Performance criteria of methods allow evaluation against a common standard. The more-common performance criteria for detection methods are precision, accuracy, sensitivity, and specificity, which together specifically address other terms used to describe the performance of a method, such as applicability, selectivity, calibration, trueness, precision, recovery, operating range, limit of quantitation, limit of detection, and ruggedness. Performance criteria should provide objective tools to accept or reject specific methods, to validate them, to ensure compatibility between validated methods, and be used on a routine basis to reject data outside an acceptable range of variability. When selecting a method of detection, it is also important to consider its applicability, its field of applications, and its limitations, by including factors such as its ability to detect the target analyte in a given matrix, the duration of the analyses, its cost effectiveness, and the necessary sample sizes for testing. Thus, the current GMO detection methods should be evaluated against a common set of performance criteria.

  6. MDS clinical diagnostic criteria for Parkinson's disease

    NARCIS (Netherlands)

    Postuma, R.B.; Berg, D; Stern, M.; Poewe, W.; Olanow, C.W.; Oertel, W.; Obeso, J.; Marek, K.; Litvan, I.; Lang, A.E.; Halliday, G.; Goetz, C.G.; Gasser, T.; Dubois, B.; Chan, P.; Bloem, B.R.; Adler, C.H.; Deuschl, G.

    2015-01-01

    This document presents the Movement Disorder Society Clinical Diagnostic Criteria for Parkinson's disease (PD). The Movement Disorder Society PD Criteria are intended for use in clinical research but also may be used to guide clinical diagnosis. The benchmark for these criteria is expert clinical di

  7. 10 CFR 905.36 - Marketing criteria.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Marketing criteria. 905.36 Section 905.36 Energy DEPARTMENT OF ENERGY ENERGY PLANNING AND MANAGEMENT PROGRAM Power Marketing Initiative § 905.36 Marketing criteria. Western shall retain applicable provisions of existing marketing criteria for projects...

  8. 7 CFR 1570.20 - Criteria.

    Science.gov (United States)

    2010-01-01

    ... AGRICULTURE EXPORT BONUS PROGRAMS Sunflowerseed Oil Assistance Program and Cottonseed Oil Assistance Program Criteria § 1570.20 Criteria. The criteria considered by FAS in reviewing proposals for SOAP and COAP..., expanding, or maintaining markets for U.S. sunflowerseed and/or cottonseed oil; (b) The subsidy...

  9. 7 CFR 1494.1101 - Criteria.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Criteria. 1494.1101 Section 1494.1101 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS EXPORT BONUS PROGRAMS Dairy Export Incentive Program Criteria § 1494.1101 Criteria. The...

  10. Criteria for obtaining and interpreting breast thermagrams.

    Science.gov (United States)

    Lapayowker, M S; Barash, I; Byrne, R; Change, J; Dodd, G; Farrell, C; Haberman, J D; Isard, H J; Threatt, B

    1976-11-01

    The thermal and graphic criteria which should be used to evaluate breast thermograms are outlined. Thermograms are then categorized as normal, suspicious, or abnormal on the basis of the criteria outlined. It is hoped that these criteria can be used widely to standardize breast thermographic evaluation.

  11. Evaluation of safety criteria on LOCA and RIA for high burnup nuclear fuel

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Sun Ki; Bang, Je Geon; Kim, Dae Ho; Yang, Yong Sik; Song, Keun Woo

    2007-12-15

    Comprehensive researches in many countries and some international research programs to investigate the applicability to high burnup nuclear fuels have been performing as the existing safety criteria of DBA such as LOCA and RIA was established several decades ago. In this report, main research programs for the safety criteria of DBA such as LOCA and RIA are introduced, and also the current status on the modification of the safety criteria are also introduced.

  12. All Roads Lead to Rome: Update on Rome III Criteria and New Treatment Options

    OpenAIRE

    Shih, David Q.; Kwan, Lola Y.

    2007-01-01

    The recently published Rome III criteria reflect current understanding of functional gastrointestinal disorders. These criteria include definitions of these conditions and their pathophysiologic subtypes and offer guidelines for their management. At the 2006 Annual Scientific Meeting of the American College of Gastroenterology, a panel of experts discussed these criteria as they pertain to irritable bowel syndrome, functional dyspepsia, and chronic constipation. This article reviews the panel...

  13. AMBIENT AQUATIC LIFE WATER QUALITY CRITERIA FOR ...

    Science.gov (United States)

    Nonylphenol is a toxic breakdown product of nonylphenol ethoxylate (NPE) surfactants. NPE surfactants are used in industrial cleaning applications and pesticide formulations. EPA published a draft ambient water quality criteria document for nonylphenol in January 2004. This document contains ambient water quality criteria for the protection of aquatic organisms and their uses. Acute and chronic criteria recommendations have been developed for the protection of aquatic life in both freshwater and saltwater. These criteria are published pursuant to Section 304 (a) of the Clean Water Act (CWA) and serve as technical information for States for establishing criteria within their State Water Quality Standards.

  14. Diagnostic criteria in proliferative verrucous leukoplakia: evaluation.

    Science.gov (United States)

    García-Chías, Begoña; Casado-De La Cruz, Laura; Esparza-Gómez, Germán-Carlos; Cerero-Lapiedra, Rocío

    2014-07-01

    to evaluate the ability of the diagnostic criteria proposed by Cerero et al in 2010 to perform an early diagnose in patients with proliferative verrucous leukoplakia. retrospective study with patients diagnosed with leukoplakia at Oral Medicine Service at Oral Medicine and Surgery Department at Dentistry Faculty at Universidad Complutense of Madrid. the criteria were applied in 116 patients, turning positive in 40 cases. Out of these, 24 (60%) had been previously diagnosed with PVL. Most frequent criteria were major criteria A and E, concerning lesion's site and histopathology, and minor criteria b and c, concerning sex and smoking habit. diagnostic criteria developed by Cerero et al can be a useful tool for an early diagnose of PVL, as in 60% of the cases, the criteria would have allowed to make an early diagnose of the disease.

  15. Do PICU patients meet technical criteria for performing indirect calorimetry?

    Science.gov (United States)

    Beggs, Megan R; Garcia Guerra, Gonzalo; Larsen, Bodil M K

    2016-10-01

    Indirect calorimetry (IC) is considered gold standard for assessing energy needs of critically ill children as predictive equations and clinical status indicators are often unreliable. Accurate assessment of energy requirements in this vulnerable population is essential given the high risk of over or underfeeding and the consequences thereof. The proportion of patients and patient days in pediatric intensive care (PICU) for which energy expenditure (EE) can be measured using IC is currently unknown. In the current study, we aimed to quantify the daily proportion of consecutive PICU patients who met technical criteria to perform indirect calorimetry and describe the technical contraindications when criteria were not met. Prospective, observational, single-centre study conducted in a cardiac and general PICU. All consecutive patients admitted for at least 96 h were included in the study. Variables collected for each patient included age at admission, admission diagnosis, and if technical criteria for indirect calorimetry were met. Technical criteria variables were collected within the same 2 h each morning and include: provision of supplemental oxygen, ventilator settings, endotracheal tube (ETT) leak, diagnosis of chest tube air leak, provision of external gas support (i.e. nitric oxide), and provision of extracorporeal membrane oxygenation (ECMO). 288 patients were included for a total of 3590 patient days between June 2014 and February 2015. The main reasons for admission were: surgery (cardiac and non-cardiac), respiratory distress, trauma, oncology and medicine/other. The median (interquartile range) patient age was 0.7 (0.3-4.6) years. The median length of PICU stay was 7 (5-14) days. Only 34% (95% CI, 32.4-35.5%) of patient days met technical criteria for IC. For patients less than 6 months of age, technical criteria were met on significantly fewer patient days (29%, p technical criteria for IC on any day during their PICU stay. Most frequent reasons for

  16. Criteria procedure development for tender in construction design

    Directory of Open Access Journals (Sweden)

    Malykha Galina Gennad’evna

    order". The article describes in detail the above evaluation criteria (sub-criteria and presents a new procedure of evaluation of competitive bids, which will allow combining its new components with those existing under the law and giving the actual result of their interaction with each other in determination of a winner, i.e. a more well-deserved candidate (a tenderer. Thus the requirements given above are met, the participants in order placement will be able to declare themselves as organizations that are highly skilled, fair and able to perform the high-quality design works, know how to perform work in due time and in strict compliance with the current regulations of the Russian Federation and are able not only to show a creative approach to solving the objectives, but also to create a project characterized by both architectural and artistic aesthetics and its high technological effectiveness.

  17. Spin current

    CERN Document Server

    Valenzuela, Sergio O; Saitoh, Eiji; Kimura, Takashi

    2012-01-01

    In a new branch of physics and technology called spin-electronics or spintronics, the flow of electrical charge (usual current) as well as the flow of electron spin, the so-called 'spin current', are manipulated and controlled together. This book provides an introduction and guide to the new physics and application of spin current.

  18. State-of-Science Approaches to Determine Sensitive Taxa for Water Quality Criteria Derivation

    Science.gov (United States)

    Current Ambient Water Quality Criteria (AWQC) guidelines specify pre-defined taxa diversity requirements, which has limited chemical-specific criteria development in the U.S. to less than 100 chemicals. A priori knowledge of sensitive taxa to toxicologically similar groups of che...

  19. 20 CFR 641.430 - What are the eligibility criteria that each applicant must meet?

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false What are the eligibility criteria that each..., Eligibility, and Award Requirements § 641.430 What are the eligibility criteria that each applicant must meet... disruption for current participants if there is a change in project sponsor and/or location, and its plan...

  20. Brain death criteria formulated for transplantation purposes: fact or myth?

    Science.gov (United States)

    Pabisiak, Krzysztof

    2016-01-01

    Medical progress has moved the boundaries of life that were set many centuries ago. The development of medical techniques has allowed us to witness cases that were unknown prior to the introduction of reanimation procedures and mechanical ventilation. Towards the end of the 1950s, the term "irreversible coma" was coined, and has evolved into what is currently known as the "brain death" concept. This latter concept, proposed in 1968, is very often referred to as the new definition of death, even in medical circles. What, up until this time, used to be the classic definition of death, namely cessation of circulation and respiration, should now be recognized as the classic criteria for death. Indeed, the new criteria for recognizing death has not resulted in changing the current criteria, but in complementing them. The first part of this paper presents brief descriptions of death in the humanities over the centuries and the impact of progress in medicine on changes in how death is defined today. The second part brings to light the complexity of creating the foundations of the neurological criteria for death. The integration of concepts from two complementary medical fields - neurology and transplantology - is described. Although for some period of time they have been linked together, they may grow independently in the future. The jargon phrase "brain death" is nowadays recognized as synonym of death, but in fact should be considered tantamount to declaring pronouncing a person's death.

  1. Identifying Luminous AGN in Deep Surveys: Revised IRAC Selection Criteria

    CERN Document Server

    Donley, J L; Brusa, M; Capak, P; Cardamone, C N; Civano, F; Ilbert, O; Impey, C D; Kartaltepe, J S; Miyaji, T; Salvato, M; Sanders, D B; Trump, J R; Zamorani, G

    2012-01-01

    Spitzer IRAC selection is a powerful tool for identifying luminous AGN. For deep IRAC data, however, the AGN selection wedges currently in use are heavily contaminated by star-forming galaxies, especially at high redshift. Using the large samples of luminous AGN and high-redshift star-forming galaxies in COSMOS, we redefine the AGN selection criteria for use in deep IRAC surveys. The new IRAC criteria are designed to be both highly complete and reliable, and incorporate the best aspects of the current AGN selection wedges and of infrared power-law selection while excluding high redshift star-forming galaxies selected via the BzK, DRG, LBG, and SMG criteria. At QSO-luminosities of log L(2-10 keV) (ergs/s) > 44, the new IRAC criteria recover 75% of the hard X-ray and IRAC-detected XMM-COSMOS sample, yet only 38% of the IRAC AGN candidates have X-ray counterparts, a fraction that rises to 52% in regions with Chandra exposures of 50-160 ks. X-ray stacking of the individually X-ray non-detected AGN candidates lead...

  2. Admission Criteria for MBA Programs

    Directory of Open Access Journals (Sweden)

    Silvana Dakduk

    2016-11-01

    Full Text Available This paper reports a review of studies on admission criteria for MBA programs. The method consisted in a literary review based on a systematic search in international databases (Emerald, ABI/INFORM Global, ProQuest Education Journals, ProQuest European Business, ProQuest Science Journal, ProQuest Research Library, ProQuest Psychology Journals, ProQuest Social Science Journals and Business Source Complete of studies published from January 1990 to December 2013, which explore the academic performance of students or graduates of MBA programs. A quantitative review was performed. Results show that most researchers studied relations between GMAT (Graduate Management Admission Test and UGPA (Undergraduate Grade Point Average as predictors of GGPA (Graduate Grade Point Average. On the other hand, work experience and personal traits (such as personality, motivation, learning strategies, self-efficacy beliefs and achievement expectations and their relation with GGPA had been less studied, and results are not consistent enough to consider them valid predictors of student performance at this time.

  3. Bioethics and conflicting ethical criteria.

    Science.gov (United States)

    George, Michael

    2002-01-01

    Some of the major problematic issues in contemporary ethical discourse are highlighted in the field of bioethics. The need to incorporate new understandings and foundational shifts in essential criteria because of technological advances in the areas of medicine and human sciences increasingly challenges traditional and accepted notions of ethics. As the possibilities of technical progress increase, more and more pressure is put on traditional understandings of the human person, identity, and value. In the face of ethical relativism and emotivism, which are already widespread in social and political discourse, the immediacy of bioethics as a response to technology and its impact on human lives reinforces the need for ethics to become interdisciplinary, while attempting to provide some coherence to both the questions and the responses that contemporary life generates. In this paper, the author intends to sketch the outlines of some of these problems, and suggest one approach which might allow a certain methodical intelligibility to emerge which takes into account shifts in consciousness and the dependence on historically grounded perspective.

  4. Selection criteria for dental radiography

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-07-01

    The Faculty of General Dental Practitioners (UK) has a declared commitment to 'improving the standards of patient care'. By the provision of standards and guidelines it aims to help the profession to achieve this goal. Standards and guidelines are simply tools a dentist may use to improve treatment planning and care outcomes. The Self-Assessment Manual and Standards, SAMS, first published in 1991, is now well known to the profession and has become a frequently quoted source in clinical audit and quality assurance initiatives. Since its publication the scientific methodology of systematic reviews of the literature has progressed dramatically and this book is based on these developments. Evidence-based care is well established in medicine and dentistry and these selection criteria and guidelines follow these established protocols by basing advice on the available scientific evidence wherever possible. This book's purpose is a practical one, it is not intended to be limiting or restrictive but to be useful in the decision-making process. This is the first in a series of standards documents from the FGDP(UK) which are based on reviews of the scientific literature and employ the Scottish Intercollegiate Guideline Network (SIGN) methodology for guideline production. They are not constraints but an aid to effective treatment planning and patient care.

  5. Investigation of Sustainable Housing Criteria

    Directory of Open Access Journals (Sweden)

    roshanfekr Somayeh

    2016-01-01

    Full Text Available Recently, much attention has been paid to sustainable development in cities. The quality of human life is directly related to environmental quality. Because many people live in cities as a place of social, economic and cultural relationships, certain issues such as environmental crises, energy, air and noise pollution and traffic jams are some of the factors that can alter the quality of human life. Therefore, in order to improve the quality of human life, attention to sustainable development (or sustainability in cities is proposed. Sustainable building has a comprehensive significance that begins with the conception of negative and positive impacts on the environment. Several descriptions of sustainable or green buildings have been created; however, they all pursue one goal, which is to create sustainable urban developments and protection of the environment. The quality of indoor environments, materials, and energy consumption, water usage, the impact of building construction processes and building maintenance are some of the factors that affect the environment and sustainability. Sustainable building is an attempt to relieve the minus impacts on the environment that occur during a building’s lifetime. This research investigates the important factors that have relevance to green buildings and introduces several criteria of sustainable housing.

  6. DOES THE MAASTRICHT CONVERGENCE CRITERIA WORK?

    Directory of Open Access Journals (Sweden)

    Karsai Zoltán-Krisztián

    2012-12-01

    Full Text Available During its 13 year history, the euro area experienced the most severe economic downturn in the late 2000s as a result of the 2007 financial-economic crisis stemming from the US banking sector. The crisis in the monetary union, besides posting a significant economic and social cost, revealed several weaknesses not just of the currency block as a whole, but also of its constituting members, which were masked by the prosperous economic environment characteristic for the 2000s. These conditions have put to the test the solidarity among the euro zone members, or in other words the existence of the currency block. One important problem of the currency block is the lack of harmony between the fiscal and economic policies of the member states, creating several and occasionally very divergent parts of the currency block. The aim of this research is to enhance the Maastricht convergence criteria’s and the Stability and Growth Pact’s role as a monitoring mechanism, allowing them to become more informative tools for the policy makers. For this, based on the relevant literature, we propose new potential explanatory variables which could enhance the role of the Maastricht convergence criteria and the Stability and Growth Pact. Some of the studied variables, like indebtedness of the private sector, capital flow compared to the size of the economy, government revenue compared to total public debt and current account balance help in enforcing the nominal convergence, while others (real labour productivity contribute to the real convergence. The explanatory power of the proposed variables are investigated in the case of France, Germany, Greece, Ireland, Italy, Portugal and Spain for the period comprised between 2000Q1-2011Q4. Results of the research show that with the exception of government revenue compared to total public debt, all proposed variables have significant explanatory power regarding the evolution of the state of the economy in all

  7. NWTS program criteria for mined geologic disposal of nuclear wasite: site performance criteria

    Energy Technology Data Exchange (ETDEWEB)

    None

    1981-02-01

    This report states ten criteria governing the suitability of sites for mined geologic disposal of high-level radioactive waste. The Department of Energy will use these criteria in its search for sites and will reevaluate their use when the Nuclear Regulatory Commission issues radioactive waste repository rules. These criteria encompass site geometry, geohydrology, geochemistry, geologic characteristics, tectonic environment, human intrusion, surface characteristics, environment, and potential socioeconomic impacts. The contents of this document include background discussion, site performance criteria, and appendices. The background section describes the waste disposal system, the application of the site criteria, and applicable criteria from NWTS-33(1) - Program Objectives, Functional Requirements and System Performance Criteria. Appendix A, entitled Comparison with Other Siting Criteria compares the NWTS criteria with those recommended by other agencies. Appendix B contains DOE responses to public comments received on the January 1980 draft of this document. Appendix C is a glossary.

  8. [Primary childhood vasculitis new classification criteria

    DEFF Research Database (Denmark)

    Herlin, T.; Nielsen, Susan

    2008-01-01

    Primary vasculitis is seen in both adults and children, but some of the diseases like Kawasaki disease occur primarily in children. The Chapel Hill Classification Criteria for primary vasculitis refers to the size of vessels but has not been validated in children. Recently, new criteria for the c......Primary vasculitis is seen in both adults and children, but some of the diseases like Kawasaki disease occur primarily in children. The Chapel Hill Classification Criteria for primary vasculitis refers to the size of vessels but has not been validated in children. Recently, new criteria...

  9. 2012 Provisional classification criteria for polymyalgia rheumatica

    DEFF Research Database (Denmark)

    Dasgupta, Bhaskar; Cimmino, Marco A; Kremers, Hilal Maradit

    2012-01-01

    The objective of this study was to develop European League Against Rheumatism/American College of Rheumatology classification criteria for polymyalgia rheumatica (PMR). Candidate criteria were evaluated in a 6-month prospective cohort study of 125 patients with new-onset PMR and 169 non-PMR compa......The objective of this study was to develop European League Against Rheumatism/American College of Rheumatology classification criteria for polymyalgia rheumatica (PMR). Candidate criteria were evaluated in a 6-month prospective cohort study of 125 patients with new-onset PMR and 169 non...

  10. Integrated criteria for covert channel auditing

    Institute of Scientific and Technical Information of China (English)

    Chang-da WANG; Shi-guang JU

    2008-01-01

    A new concept, the security level difference of a covert channel, is presented, which means the security level span from the sender to the receiver of the covert channel. Based on this, the integrated criteria for covert channel auditing are given. Whereas TCSEC (Trusted Computer System Evaluation Criteria) or CC (Common Criteria for Information Technology Security Evaluation) only use the bandwidth to evaluate the threat of covert channels, our new criteria integrate the security level difference, the bandwidth sensitive parameter, bandwidth, duration and instantaneous time of covert channels, so as to give a comprehensive evaluation of the threat of covert channels in a multilevel security system.

  11. Metamodel defined multidimensional embedded sequential sampling criteria.

    Energy Technology Data Exchange (ETDEWEB)

    Turner, C. J. (Cameron J.); Campbell, M. I. (Matthew I.); Crawford, R. H. (Richard H.)

    2004-01-01

    Collecting data to characterize an unknown space presents a series of challenges. Where in the space should data be collected? What regions are more valuable than others to sample? When have sufficient samples been acquired to characterize the space with some level of confidence? Sequential sampling techniques offer an approach to answering these questions by intelligently sampling an unknown space. Sampling decisions are made with criteria intended to preferentially search the space for desirable features. However, N-dimensional applications need efficient and effective criteria. This paper discusses the evolution of several such criteria based on an understanding of the behaviors of existing criteria, and desired criteria properties. The resulting criteria are evaluated with a variety of planar functions, and preliminary results for higher dimensional applications are also presented. In addition, a set of convergence criteria, intended to evaluate the effectiveness of further sampling are implemented. Using these sampling criteria, an effective metamodel representation of the unknown space can be generated at reasonable sampling costs. Furthermore, the use of convergence criteria allows conclusions to be drawn about the level of confidence in the metamodel, and forms the basis for evaluating the adequacy of the original sampling budget.

  12. Diagnostic criteria for sarcopenia relate differently to insulin resistance

    OpenAIRE

    Bijlsma, A. Y.; Meskers, C. G. M.; van Heemst, D.; Westendorp, R. G. J.; de Craen, A. J. M.; Maier, A. B.

    2013-01-01

    Skeletal muscle is important in insulin-stimulated glucose uptake. Sarcopenia is, therefore, a possible risk factor for insulin resistance. Currently, different diagnostic criteria for sarcopenia include low muscle mass, muscle strength, and walking speed. We assessed these muscle characteristics in relation to insulin resistance in nondiabetics. This cross-sectional study included 301 nondiabetics, mean age 65.9 years. Area under curve (AUC) calculations of insulin and glucose from a 2-h ora...

  13. IDENTIFICATION OF QUESTIONABLE EXCLUSION CRITERIA IN MENTAL DISORDER CLINICAL TRIALS USING A MEDICAL ENCYCLOPEDIA.

    Science.gov (United States)

    Ma, Handong; Weng, Chunhua

    2016-01-01

    Precision medicine requires precise evidence-based practice and precise definition of the patients included in clinical studies for evidence generalization. Clinical research exclusion criteria define confounder patient characteristics for exclusion from a study. However, unnecessary exclusion criteria can weaken patient representativeness of study designs and generalizability of study results. This paper presents a method for identifying questionable exclusion criteria for 38 mental disorders. We extracted common eligibility features (CEFs) from all trials on these disorders from ClinicalTrials.gov. Network Analysis showed scale-free property of the CEF network, indicating uneven usage frequencies among CEFs. By comparing these CEFs' term frequencies in clinical trials' exclusion criteria and in the PubMed Medical Encyclopedia for matching conditions, we identified unjustified potential overuse of exclusion CEFs in mental disorder trials. Then we discussed the limitations in current exclusion criteria designs and made recommendations for achieving more patient-centered exclusion criteria definitions.

  14. The value of the current diagnostic criteria of pulmonary invasive fungal infection after allogeneic hematopoietic stem cell transplantation%异基因造血干细胞移植后肺部侵袭性真菌感染现行诊断标准的应用价值

    Institute of Scientific and Technical Information of China (English)

    沈建良; 宫立众; 刘代红; 黄晓军

    2013-01-01

    Objective To analyze the practicality of current diagnostic criteria of invasive fungal infection (IFI) in patients with hematologic diseases/malignant tumors,so as to enhance the recognition of characteristics of pulmonary IFI after allogeneic hematopoietic stem cell transplantation (allo-HSCT).Methods The clinical features of 51 cases with IFI after allo-HSCT were analyzed retrospectively.Results Pulmonary IFI accounted for 42.1% (51/121) of the whole infectious pneumonia diagnosed among the patients admitted during the study.One (2.0%) case was proven diagnosis ; 24 (47.1%) were probable diagnosis and 26(51.0%) were possible diagnosis.The using of immuno-suppressors and corticosteroids,and the presence of graft-versus-host disease (GVHD) were the main host factors.The patients with two or more host factors simultaneously accounted for 66.7% (34/51) of all pulmonary IFI patients.Totally 94.1% (48/51) of the patients with pulmonary IFI presented nodules and/or patches as the main features in high resolution computed tomography (HRCT) scanning.The positive rates of fungal antigen detection were 58.6% for G test and 33.3% for GM test,which were relatively high.Twenty patients (39.2%) showed decrease of arterial partial pressure of oxygen and hypoxia in blood-gas analysis.Conclusions For the diagnosis of pulmonary IFI post allo-HSCT,the administration of immuno-suppressors and corticosteroids,and the presence of GVHD were the main host factors.Nodules and/or patches were the main features in HRCT image.Fungus antigen detection is the main tool to support clinical diagnosis.%目的 分析我国现行血液病/恶性肿瘤患者侵袭性真菌感染诊断标准的可操作性,提高对异基因造血干细胞移植(allo-HSCT)后肺部侵袭性真菌感染特点的认识.方法 回顾性分析连续收治的51例allo-HSCT后肺部侵袭性真菌感染病例的临床特点.结果 肺部侵袭性真菌感染共占同期收

  15. Correlation of admission criteria with dental school performance and attrition.

    Science.gov (United States)

    Sandow, Pamela L; Jones, Anne C; Peek, Chuck W; Courts, Frank J; Watson, Ronald E

    2002-03-01

    This study was conducted to provide current information on the relationship between admission criteria and dental school performance, including the association of admission criteria and dental school outcomes such as remediation and attrition. Standard tests of bivariate association and multivariate regression models appropriate for continuous and discrete dependent variables were used to examine the relationship between multiple indicators of admission criteria and dental school performance for six recent classes at the University of Florida College of Dentistry (UFCD). The admission criteria included the undergraduate science grade point average (GPA), undergraduate non-science GPA, Dental Admissions Test (DAT) academic score, Perceptual Motor Aptitude Test (PMAT) score, and admission interview score. Measures of dental school performance were the National Dental Board Examination Part I and Part II (NB-I, NB-II) scores, yearly and final dental school GPA, and academic progress through the UFCD program. In general, most admission criteria were good bivariate indicators of dental school performance. Multivariate analyses indicated that students with higher undergraduate science GPAs and DAT academic scores were more likely to achieve higher NB-I and NB-II scores. The undergraduate science GPA and admission interview score were the most consistent determinants of dental school GPA. Students with lower undergraduate science GPAs, DAT academic scores, and PMAT scores were more likely to remediate, to repeat an academic year, or to be dismissed. Although bivariate differences were observed in several admission criteria of students who remediated one or more courses, repeated an academic year, or were dismissed only the undergraduate science GPA and the PMAT score were indicators of programmatic progress in the multivariate analysis.

  16. Rotorcraft handling-qualities design criteria development

    Science.gov (United States)

    Aiken, Edwin W.; Lebacqz, J. Victor; Chen, Robert T. N.; Key, David L.

    1988-01-01

    Joint NASA/Army efforts at the Ames Research Center to develop rotorcraft handling-qualities design criteria began in earnest in 1975. Notable results were the UH-1H VSTOLAND variable stability helicopter, the VFA-2 camera-and-terrain-board simulator visual system, and the generic helicopter real-time mathematical model, ARMCOP. An initial series of handling-qualities studies was conducted to assess the effects of rotor design parameters, interaxis coupling, and various levels of stability and control augmentation. The ability to conduct in-flight handling-qualities research was enhanced by the development of the NASA/Army CH-47 variable-stability helicopter. Research programs conducted using this vehicle include vertical-response investigations, hover augmentation systems, and the effects of control-force characteristics. The handling-qualities data base was judged to be sufficient to allow an update of the military helicopter handling-qualities specification, MIL-H-8501. These efforts, including not only the in-house experimental work but also contracted research and collaborative programs performed under the auspices of various international agreements. The report concludes by reviewing the topics that are currently most in need of work, and the plans for addressing these topics.

  17. Prioritisation criteria for the selection of new diagnostic technologies for evaluation

    Directory of Open Access Journals (Sweden)

    Linden-Phillips Luan

    2010-05-01

    Full Text Available Abstract Background Currently there is no framework for those involved in the identification, evaluation and prioritisation of new diagnostic technologies. Therefore we aimed to develop prioritisation criteria for the assessment of new diagnostic technologies, by gaining international consensus on not only which criteria should be used, but also their relative importance. Methods A two-round Delphi process was used to generate consensus amongst an international panel of twenty-six experts on priority criteria for diagnostic health technology assessment. Participants represented a range of health care and related professions, including government, industry, health services and academia. Results Based on the responses to the first questionnaire 18 criteria were placed into three categories: high, intermediate and moderate priority. For 16 of the 18 criteria, agreement with the categorisation of the criteria into the high, intermediate and moderate categories was high at ≥ 70% (10 had agreement ≥ 80%. A further questionnaire and panel discussion reduced the criteria to 16 and two categories; seven were classified as high priority and nine intermediate. Conclusions This study proposes an objective structure of prioritisation criteria to use when assessing new diagnostic technologies, based on an expert consensus process. The value of these criteria is that no one single component should be used as the decisive driver for prioritisation of new diagnostic technologies for adoption in healthcare settings. Future studies should be directed at establishing the value of these prioritisation criteria across a range of healthcare settings.

  18. Diagnostic criteria of autoimmune hepatitis.

    Science.gov (United States)

    Liberal, Rodrigo; Grant, Charlotte R; Longhi, Maria Serena; Mieli-Vergani, Giorgina; Vergani, Diego

    2014-01-01

    Autoimmune hepatitis (AIH) is a chronic immune-mediated liver disorder characterised by female preponderance, elevated transaminase and immunoglobulin G levels, seropositivity for autoantibodies and interface hepatitis. Presentation is highly variable, therefore AIH should be considered during the diagnostic workup of any increase in liver enzyme levels. A set of inclusion and exclusion criteria for the diagnosis of AIH have been established by the International Autoimmune Hepatitis Group (IAIHG). There are two main types of AIH: type 1, positive for anti-nuclear (ANA) and/or anti-smooth muscle antibodies (SMAs) and type 2, defined by the presence of anti-liver kidney microsomal antibody type 1 (LKM-1) and/or anti-liver cytosol type 1 (LC-1) autoantibodies. The central role of autoantibodies in the diagnosis of AIH has led the IAIHG to produce a consensus statement detailing appropriate and effective methods for their detection. Autoantibodies should be tested by indirect immunofluorescence at an initial dilution of 1/40 in adults and 1/10 in children on a freshly prepared rodent substrate that includes kidney, liver and stomach sections to allow for the simultaneous detection of all reactivities relevant to AIH. Anti-LKM-1 is often confused with anti-mitochondrial antibody (AMA) if rodent kidney is used as the sole immunofluorescence substrate. The identification of the molecular targets of anti-LKM-1 and AMA has led to the establishment of immuno-assays based on the use of the recombinant or purified autoantigens. Perinuclear anti-nuclear neutrophil antibody (p-ANNA) is an additional marker of AIH-1; anti soluble liver antigen (SLA) antibodies are specific for autoimmune liver disease, can be present in AIH-1 and AIH-2 and are associated with a more severe clinical course. Anti-SLA are detectable by ELISA or radio-immuno-assays, but not by immunofluorescence. AIH is exquisitely responsive to immunosuppressive treatment, which should be instituted promptly to

  19. Criteria equivalent to the Riemann Hypothesis

    Science.gov (United States)

    Cisło, J.; Wolf, M.

    2008-11-01

    We give a brief overview of a few criteria equivalent to the Riemann Hypothesis. Next we concentrate on the Riesz and Báez-Duarte criteria. We prove that they are equivalent and we provide some computer data to support them.

  20. 16 CFR 1031.15 - Communication criteria.

    Science.gov (United States)

    2010-01-01

    ... nature and a report of each oral communication of a substantive nature between a Commission official or... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Communication criteria. 1031.15 Section 1031... Communication criteria. (a) Commission officials and employees, who are not in the positions listed in §...

  1. Diagnostic criteria for DCD : Past and future

    NARCIS (Netherlands)

    Smits-Engelsman, Bouwien; Schoemaker, Marina; Delabastita, Tijs; Hoskens, Jasmine; Geuze, Reint

    The aim of this review was to gather information on how well authors comply to DSM criteria in their description and selection of children with DCD. We investigated which selection criteria were used in experimental and intervention studies published in the last 5 years (2010-2014). Results on 176

  2. Revised response criteria for malignant lymphoma

    DEFF Research Database (Denmark)

    Cheson, Bruce D; Pfistner, Beate; Juweid, Malik E

    2007-01-01

    Standardized response criteria are needed to interpret and compare clinical trials and for approval of new therapeutic agents by regulatory agencies.......Standardized response criteria are needed to interpret and compare clinical trials and for approval of new therapeutic agents by regulatory agencies....

  3. 45 CFR 9.4 - Criteria.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Criteria. 9.4 Section 9.4 Public Welfare... SCIENTISTS, ENGINEERS, AND STUDENTS § 9.4 Criteria. (a) The official permitting use of Department facilities must determine that it would be consistent with the programs of his activity to participate....

  4. 2012 provisional classification criteria for polymyalgia rheumatica

    DEFF Research Database (Denmark)

    Dasgupta, Bhaskar; Cimmino, Marco A; Maradit-Kremers, Hilal

    2012-01-01

    The objective of this study was to develop EULAR/ACR classification criteria for polymyalgia rheumatica (PMR). Candidate criteria were evaluated in a 6-month prospective cohort study of 125 patients with new onset PMR and 169 non-PMR comparison subjects with conditions mimicking PMR. A scoring al...

  5. [Criteria of scientific validity in research].

    Science.gov (United States)

    Pelletier, Céline; Pagé, Ginette

    2002-03-01

    The purpose of this article is to present the evaluative criteria of qualitative and quantitative research. Philosophical foundations of positivism, postpositivism and constructivism are explored. Triangulation and crystallization expose the controversies about them. Finally, Lincoln and Guba criteria are retained for the evaluation of qualitative and quantitative research.

  6. Education Criteria for Performance Excellence, 2002.

    Science.gov (United States)

    National Inst. of Standards and Technology, Gaithersburg, MD.

    The education criteria presented in this guide are designed to help organizations use an integrated approach to organizational performance management that results in delivery of ever-improving value to students and stakeholders. Implementation of the criteria will contribute to improvement of education quality, improvement of overall…

  7. Aspirational Model Teaching Criteria for Psychology

    Science.gov (United States)

    Richmond, Aaron S.; Boysen, Guy A.; Gurung, Regan A. R.; Tazeau, Yvette N.; Meyers, Steven A.; Sciutto, Mark J.

    2014-01-01

    In 2011, the Society for the Teaching of Psychology commissioned a presidential task force to document teaching criteria for model psychology teachers in undergraduate education. The resulting list of criteria reflects activities related to face-to-face course interaction and online teaching, training, and education; course design; implementation…

  8. On approximating multi-criteria TSP

    NARCIS (Netherlands)

    Manthey, Bodo; Albers, S.; Marion, J.-Y.

    2009-01-01

    We present approximation algorithms for almost all variants of the multi-criteria traveling salesman problem (TSP), whose performances are independent of the number $k$ of criteria and come close to the approximation ratios obtained for TSP with a single objective function. We present randomized app

  9. Screening criteria for design basis events

    Energy Technology Data Exchange (ETDEWEB)

    Paddleford, D.F.; Wooten, L.A.

    1992-01-01

    A risk based screening criteria was developed to assist in determining whether issues raised during K-reactor restart safety analyses needed to be part of the design basis, and if so, to guide the degree of conservatism in the analysis. This paper describes the development of this criterias existing precedents, and its implementation guidelines and restrictions.

  10. Screening criteria for design basis events

    Energy Technology Data Exchange (ETDEWEB)

    Paddleford, D.F.; Wooten, L.A.

    1992-12-31

    A risk based screening criteria was developed to assist in determining whether issues raised during K-reactor restart safety analyses needed to be part of the design basis, and if so, to guide the degree of conservatism in the analysis. This paper describes the development of this criterias existing precedents, and its implementation guidelines and restrictions.

  11. Proposed diagnostic criteria for internet addiction.

    Science.gov (United States)

    Tao, Ran; Huang, Xiuqin; Wang, Jinan; Zhang, Huimin; Zhang, Ying; Li, Mengchen

    2010-03-01

    The objective of this study was to develop diagnostic criteria for internet addiction disorder (IAD) and to evaluate the validity of our proposed diagnostic criteria for discriminating non-dependent from dependent internet use in the general population. This study was conducted in three stages: the developmental stage (110 subjects in the survey group; 408 subjects in the training group), where items of the proposed diagnostic criteria were developed and tested; the validation stage (n = 405), where the proposed criteria were evaluated for criterion-related validity; and the clinical stage (n = 150), where the criteria and the global clinical impression of IAD were evaluated by more than one psychiatrist to determine inter-rater reliability. The proposed internet addiction diagnostic criteria consisted of symptom criterion (seven clinical symptoms of IAD), clinically significant impairment criterion (functional and psychosocial impairments), course criterion (duration of addiction lasting at least 3 months, with at least 6 hours of non-essential internet usage per day) and exclusion criterion (exclusion of dependency attributed to psychotic disorders). A diagnostic score of 2 + 1, where the first two symptoms (preoccupation and withdrawal symptoms) and at least one of the five other symptoms (tolerance, lack of control, continued excessive use despite knowledge of negative effects/affects, loss of interests excluding internet, and use of the internet to escape or relieve a dysphoric mood) was established. Inter-rater reliability was 98%. Our findings suggest that the proposed diagnostic criteria may be useful for the standardization of diagnostic criteria for IAD.

  12. 22 CFR 146.505 - Employment criteria.

    Science.gov (United States)

    2010-04-01

    ... Employment in Education Programs or Activities Prohibited § 146.505 Employment criteria. A recipient shall... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Employment criteria. 146.505 Section 146.505 Foreign Relations DEPARTMENT OF STATE CIVIL RIGHTS NONDISCRIMINATION ON THE BASIS OF SEX IN...

  13. 22 CFR 229.505 - Employment criteria.

    Science.gov (United States)

    2010-04-01

    ... Employment in Education Programs or Activities Prohibited § 229.505 Employment criteria. A recipient shall... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Employment criteria. 229.505 Section 229.505 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT NONDISCRIMINATION ON THE BASIS OF SEX IN...

  14. 34 CFR 104.13 - Employment criteria.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Employment criteria. 104.13 Section 104.13 Education Regulations of the Offices of the Department of Education OFFICE FOR CIVIL RIGHTS, DEPARTMENT OF EDUCATION... Employment Practices § 104.13 Employment criteria. (a) A recipient may not make use of any employment test...

  15. 28 CFR 54.505 - Employment criteria.

    Science.gov (United States)

    2010-07-01

    ... EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Employment in Education Programs or Activities Prohibited § 54.505 Employment criteria. A... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Employment criteria. 54.505 Section...

  16. Diagnostic criteria for DCD : Past and future

    NARCIS (Netherlands)

    Smits-Engelsman, Bouwien; Schoemaker, Marina; Delabastita, Tijs; Hoskens, Jasmine; Geuze, Reint

    2015-01-01

    The aim of this review was to gather information on how well authors comply to DSM criteria in their description and selection of children with DCD. We investigated which selection criteria were used in experimental and intervention studies published in the last 5 years (2010-2014). Results on 176 p

  17. 7 CFR 658.5 - Criteria.

    Science.gov (United States)

    2010-01-01

    ..., fruit trees and vines, field terraces, drainage, irrigation, waterways, or other soil and water... agricultural use of surrounding farmland—0 points (c) Corridor-type Site Assessment Criteria. The following criteria are to be used for projects that have a linear or corridor-type site configuration connecting...

  18. Criteria for Producing CLIL Learning Material

    Science.gov (United States)

    Mehisto, Peeter

    2012-01-01

    This article first describes some general criteria that can be applied to the development of any type of learning materials. Second, the article lists criteria for creating CLIL (content and language integrated learning)-specific learning materials, and provides examples of how to apply each proposed criterion whilst also providing a corresponding…

  19. Hybrid multiple criteria decision-making methods

    DEFF Research Database (Denmark)

    Zavadskas, Edmundas Kazimieras; Govindan, K.; Antucheviciene, Jurgita

    2016-01-01

    Formal decision-making methods can be used to help improve the overall sustainability of industries and organisations. Recently, there has been a great proliferation of works aggregating sustainability criteria by using diverse multiple criteria decision-making (MCDM) techniques. A number of revi...

  20. 46 CFR 349.3 - Certification criteria.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Certification criteria. 349.3 Section 349.3 Shipping... RIGHTS OF CERTAIN MERCHANT SEAMEN § 349.3 Certification criteria. The Administrator shall apply the... ordered to active duty. It shall be the responsibility of each applicant for certification to...

  1. Current limiters

    Energy Technology Data Exchange (ETDEWEB)

    Loescher, D.H. [Sandia National Labs., Albuquerque, NM (United States). Systems Surety Assessment Dept.; Noren, K. [Univ. of Idaho, Moscow, ID (United States). Dept. of Electrical Engineering

    1996-09-01

    The current that flows between the electrical test equipment and the nuclear explosive must be limited to safe levels during electrical tests conducted on nuclear explosives at the DOE Pantex facility. The safest way to limit the current is to use batteries that can provide only acceptably low current into a short circuit; unfortunately this is not always possible. When it is not possible, current limiters, along with other design features, are used to limit the current. Three types of current limiters, the fuse blower, the resistor limiter, and the MOSFET-pass-transistor limiters, are used extensively in Pantex test equipment. Detailed failure mode and effects analyses were conducted on these limiters. Two other types of limiters were also analyzed. It was found that there is no best type of limiter that should be used in all applications. The fuse blower has advantages when many circuits must be monitored, a low insertion voltage drop is important, and size and weight must be kept low. However, this limiter has many failure modes that can lead to the loss of over current protection. The resistor limiter is simple and inexpensive, but is normally usable only on circuits for which the nominal current is less than a few tens of milliamperes. The MOSFET limiter can be used on high current circuits, but it has a number of single point failure modes that can lead to a loss of protective action. Because bad component placement or poor wire routing can defeat any limiter, placement and routing must be designed carefully and documented thoroughly.

  2. An objective approach to determining criteria weights

    Directory of Open Access Journals (Sweden)

    Milić R. Milićević

    2012-01-01

    Full Text Available This paper presents an objective approach to determining criteria weights that can be successfully used in multiple criteria models. The methods of entropy, CRITIC and FANMA are presented in this paper as well as a possible combination of the methods of objective and subjective approaches. Although based on different theoretical settings, and therefore with different algorithms of realization, all methods have a decision matrix as a starting point. An objective approach to determining the weight of criteria eliminates the negative impacts of a decision maker on criteria weights as well as on the final solution of multicriteria problems. The main aim of this paper is to systematize description procedures as a kind of help when encountering a problem of determining the criteria weights for solving multicriteria tasks. A possibility of the method application is shown in a numerical example.

  3. Diagnostic criteria for DCD: Past and future.

    Science.gov (United States)

    Smits-Engelsman, Bouwien; Schoemaker, Marina; Delabastita, Tijs; Hoskens, Jasmine; Geuze, Reint

    2015-08-01

    The aim of this review was to gather information on how well authors comply to DSM criteria in their description and selection of children with DCD. We investigated which selection criteria were used in experimental and intervention studies published in the last 5 years (2010-2014). Results on 176 papers are summarized. Compliance to the DSM criteria has improved over this time period. In general, detailed information was provided on motor performance using standardized test scores and cut-off values are reported. Method sections were far less detailed about other DSM criteria (i.e., whether motor coordination problems interfered with activities of daily living and how IQ, other medical conditions or co-occurring disorders were checked). Views on how the new DSM-5 criteria could be specified for clinical and research use are discussed.

  4. Evolving treatment plan quality criteria from institution-specific experience.

    Science.gov (United States)

    Ruan, D; Shao, W; Demarco, J; Tenn, S; King, C; Low, D; Kupelian, P; Steinberg, M

    2012-05-01

    consistency, by evolving the plan quality criteria from institution-specific experience, complementary to national standards. The validity of the proposed method was demonstrated with a prototype system on prostate stereotactic body radiotherapy (SBRT) cases. The current study uses direct and indirect DVH endpoints for plan quality evaluation, but the infrastructure proposed here applies to general outcome data as well. The authors expect forward evaluation together with intelligent update based on evidence-based learning, which will evolve the clinical practice for improved efficiency, consistency, and ultimately better treatment outcome.

  5. Interpretation criteria in Western blot diagnosis of Lyme borreliosis.

    Science.gov (United States)

    Mavin, S; McDonagh, S; Evans, R; Milner, R M; Chatterton, J M W; Ho-Yen, D O

    2011-01-01

    This study reviews the Lyme borreliosis Western blot interpretation process, including what bands are classed as specific, the number of bands needed for a positive result, the role of band intensity and the use of clinical information. In 2008, 3688 patients (4223 serum samples) were tested by enzyme immunoassay (EIA), with 832 patients tested by confirmatory in-house IgG Western blot: 272 patients were Western blot-positive, 170 were weak positive, 156 were equivocal and 234 were negative. These results were assessed, and a review of interpretation criteria from both the USA and Europe was carried out. New interpretation criteria and a testing algorithm were developed. The revised criteria changed the results in 109/3688 (3%) patients and produced significantly more Western blot-positive and weak-positive patients than with the current criteria (485 vs. 442, P blot interpretation and improved the sensitivity and robustness of their Western blot method. Using a protocol tailored to patients that incorporates clinical characteristics means that the entire process will be easier and will aid the management of patients.

  6. CASTOR GSF packaging design criteria

    Energy Technology Data Exchange (ETDEWEB)

    Burnside, M.E.

    1996-08-06

    Encapsulated vitrified materials (Isotopic Heat Sources) are currently stored in the Pacific Northwest National Laboratories (PNNL) 324 Building located in the 300 Area. As part of the 324 Building transition program, the vitrified material, encapsulated in stainless steel canisters, must be removed. These canisters were originally intended to be used by the German government, but are no longer desired. As part of an agreement with the German government, the Germans are providing the U.S. Department of Energy (DOE) with six (6) CASTOR GSF and four (4) GNS-12 casks.The canisters will be transported onsite in CASTOR GSF and GNS-12 casks for interim storage until final disposition of the material is determined.

  7. 78 FR 38091 - Airworthiness Criteria: Proposed Airship Design Criteria for Lockheed Martin Aeronautics Model...

    Science.gov (United States)

    2013-06-25

    ...] Airworthiness Criteria: Proposed Airship Design Criteria for Lockheed Martin Aeronautics Model LMZ1M Airship... on the proposed design criteria for the Lockheed Martin Aeronautics model LMZ1M airship. On March 12.... The LMZ1M is a manned cargo lifting hybrid airship incorporating a number of advanced features. The...

  8. IMPORTANCE OF MULTIPLE CRITERIA FOR PRIORITY SETTING OF HIV/AIDS INTERVENTIONS.

    Science.gov (United States)

    Tromp, Noor; Prawiranegara, Rozar; Siregar, Adiatma; Sunjaya, Deni; Baltussen, Rob

    2015-01-01

    This study describes the views of various stakeholders on the importance of different criteria for priority setting of HIV/AIDS interventions in Indonesia. Based on a general list of criteria and a focus group discussion with stakeholders (n = 6), a list was developed of thirty-two criteria that play a role in priority setting in HIV/AIDS control in West-Java province. Criteria were categorized according to the World Health Organization's health system goals and building block frameworks. People living with HIV/AIDS (n = 49), healthcare workers (HCW) (n = 41), the general population (n = 43), and policy makers (n = 22) rated the importance of thirty-two criteria on a 5-point Likert-scale. Thereafter, respondents ranked the highest rated criteria to express more detailed preferences. Stakeholders valued the following criteria as most important for the priority setting of HIV/AIDS interventions: an intervention's impact on the HIV/AIDS epidemic, reduction of stigma, quality of care, effectiveness on individual level, and feasibility in terms of current capacity of the health system (i.e., HCW, product, information, and service requirements), financial sustainability, and acceptance by donors. Overall, stakeholders' preferences for the importance of criteria are similar. Our study design outlines an approach for other settings to identify which criteria are important for priority setting of health interventions. For Indonesia, these study results may be used in priority setting processes for HIV/AIDS control and may contribute to more transparent and systematic allocation of resources.

  9. Flying qualities criteria and flight control design

    Science.gov (United States)

    Berry, D. T.

    1981-01-01

    Despite the application of sophisticated design methodology, newly introduced aircraft continue to suffer from basic flying qualities deficiencies. Two recent meetings, the DOD/NASA Workshop on Highly Augmented Aircraft Criteria and the NASA Dryden Flight Research Center/Air Force Flight Test Center/AIAA Pilot Induced Oscillation Workshop, addressed this problem. An overview of these meetings is provided from the point of view of the relationship between flying qualities criteria and flight control system design. Among the items discussed are flying qualities criteria development, the role of simulation, and communication between flying qualities specialists and control system designers.

  10. Constructed criteria: redefining merit to justify discrimination.

    Science.gov (United States)

    Uhlmann, Ericluis; Cohen, Geoffrey L

    2005-06-01

    This article presents an account of job discrimination according to which people redefine merit in a manner congenial to the idiosyncratic credentials of individual applicants from desired groups. In three studies, participants assigned male and female applicants to gender-stereotypical jobs. However, they did not view male and female applicants as having different strengths and weaknesses. Instead, they redefined the criteria for success at the job as requiring the specific credentials that a candidate of the desired gender happened to have. Commitment to hiring criteria prior to disclosure of the applicant's gender eliminated discrimination, suggesting that bias in the construction of hiring criteria plays a causal role in discrimination.

  11. Discard criteria for mine winder ropes.

    CSIR Research Space (South Africa)

    Van Zyl, M

    2000-09-01

    Full Text Available to be able to establish and propose proper discard criteria for broken wires in non-spin ropes. The discard criteria for broken wires in SABS0293 were based on a 10% reduction in strength of a rope. An expectation was therefore created that by complying... with these discard criteria, a rope would not fail as long as the rope loads did not exceed 90% of the new rope breaking strength. However, it is shown in this report that rope strands with "allowable" broken wires could fail at loads considerably lower than 90...

  12. Advanced Neutron Source radiological design criteria

    Energy Technology Data Exchange (ETDEWEB)

    Westbrook, J.L.

    1995-08-01

    The operation of the proposed Advanced Neutron Source (ANS) facility will present a variety of radiological protection problems. Because it is desired to design and operate the ANS according to the applicable licensing standards of the Nuclear Regulatory Commission (NRC), it must be demonstrated that the ANS radiological design basis is consistent not only with state and Department of Energy (DOE) and other usual federal regulations, but also, so far as is practicable, with NRC regulations and with recommendations of such organizations as the Institute of Nuclear Power Operations (INPO) and the Electric Power Research Institute (EPRI). Also, the ANS radiological design basis is in general to be consistent with the recommendations of authoritative professional and scientific organizations, specifically the National Council on Radiation Protection and Measurements (NCRP) and the International Commission on Radiological Protection (ICRP). As regards radiological protection, the principal goals of DOE regulations and guidance are to keep occupational doses ALARA [as low as (is) reasonably achievable], given the current state of technology, costs, and operations requirements; to control and monitor contained and released radioactivity during normal operation to keep public doses and releases to the environment ALARA; and to limit doses to workers and the public during accident conditions. Meeting these general design objectives requires that principles of dose reduction and of radioactivity control by employed in the design, operation, modification, and decommissioning of the ANS. The purpose of this document is to provide basic radiological criteria for incorporating these principles into the design of the ANS. Operations, modification, and decommissioning will be covered only as they are affected by design.

  13. Associations between criteria air pollutants and asthma

    Energy Technology Data Exchange (ETDEWEB)

    Koren, H.S. [Environmental Protection Agency, Chapel Hill, NC (United States)

    1995-09-01

    The evidence that asthma is increasing in prevalence is becoming increasingly compelling. This trend has been demonstrated in the United States, the United Kingdom, New Zealand, Australia, and several other Western countries. In the US, the increase is largest in the group under 18 years of age. There is mounting evidence that certain environmental air pollutants are involved in exacerbating asthma. This is based primarily on epidemiologic studies and more recent clinical studies. The U.S. Clean Air Act of 1970 provides special consideration to the class of outdoor air pollutants referred to as criteria pollutants, including O{sub 3}, sulfur dioxide (SO{sub 2}), particulate matter (PM), NO{sub x}, CO, and Pb. Standards for these pollutants are set by the US EPA with particular concern for populations at risk. Current evidence suggests that asthmatics are more sensitive to the effects of O{sub 3}, SO{sub 2} PM, and NO{sub 2}, and are therefore at risk. High SO{sub 2} and particulate concentrations have been associated with short-term increases in morbidity and mortality in the general population during dramatic air pollution episodes in the past. Controlled exposure studies have clearly shown that asthmatics are sensitive to low levels of SO{sub 2}. Exercising asthmatics exposed to SO{sub 2} develop bronchoconstriction within minutes, even at levels of 0.25 ppm. Responses are modified by air temperature, humidity, and exercise level. Recent epidemiologic studies have suggested that exposure to Pm is strongly associated with morbidity and mortality in the general population and that hospital admissions for bronchitis and asthma were associated with PM{sub 10} levels. In controlled clinical studies, asthmatics appear to be no more reactive to aerosols than healthy subjects. Consequently, it is difficult to attribute the increased mortality observed in epidemiologic studies to specific effects demonstrated in controlled human studies. 106 refs., 1 fig., 1 tab.

  14. MIGRAINE IN IRANIAN CHILDREN; WHICH CRITERIA ARE THE BEST DIAGNOSTIC CRITERIA?

    Directory of Open Access Journals (Sweden)

    A. Chitsaz

    2007-11-01

    Full Text Available ObjectiveThe aim of this study was to identify the best criteria for diagnosis of migraine in our pediatric population. Materials and MethodsA total of 85 children aged below 15 years who had been referred to the Neurology Clinic of Al-Zahra Hospital with headache as their chief complaint, were enrolled. Validated questionnaires were completed by them. The patients were evaluated using five sets of diagnostic criteria including the Vahlquist, the Prensky, the International Headache Society (IHS, the IHS-Revised (IHS-R, and the Maytal criteria; the sensitivity of each set of criteria was assessed. ResultsOf the 85 children, clinically diagnosed as having migraine, 61 (72%, 73 (86%, 75 (88%, 76 (89.5%, and 76 (89.5% met the criteria of IHS, Vahlquist, Prensky, IHS-R, and Maytal, respectively. Both the IHS-R and Maytal criteria had the highest, while the IHS criteria had the lowest sensitivity. Fifty-four children (63.5% were positive for all five sets of criteria. The application of IHS criteria for diagnosing pediatric migraine led to a smaller percentage of children with migraine being identified.ConclusionAssessment of the sensitivity of the five sets of criteria for the diagnosis of migraine revealed the inadequacies and limitations of the IHS criteria in the diagnosis of pediatric migraine.

  15. MIGRAINE IN IRANIAN CHILDREN; WHICH CRITERIA ARE THE BEST DIAGNOSTIC CRITERIA?

    Directory of Open Access Journals (Sweden)

    A. Chitsaz

    2008-11-01

    Full Text Available ObjectiveThe aim of this study was to identify the best criteria for diagnosis of migraine in our pediatric population.Materials and MethodsA total of 85 children aged below 15 years who had been referred to the Neurology Clinic of Al-Zahra Hospital with headache as their chief complaint, were enrolled. Validated questionnaires were completed by them. The patients were evaluated using five sets of diagnostic criteria including the Vahlquist, the Prensky, the International Headache Society (IHS, the IHS-Revised (IHS-R, and the Maytal criteria; the sensitivity of each set of criteria was assessed.ResultsOf the 85 children, clinically diagnosed as having migraine, 61 (72%, 73 (86%, 75 (88%, 76 (89.5%, and 76 (89.5% met the criteria of IHS, Vahlquist, Prensky, IHS-R, and Maytal, respectively. Both the IHS-R and Maytal criteria had the highest, while the IHS criteria had the lowest sensitivity. Fifty-four children (63.5% were positive for all five sets of criteria. The application of IHS criteria for diagnosing pediatric migraine led to a smaller percentage of children with migraine being identified.ConclusionAssessment of the sensitivity of the five sets of criteria for the diagnosis of migraine revealed the inadequacies and limitations of the IHS criteria in the diagnosis of pediatric migraine.Key words:Migraine, Child, Diagnosis, Headache

  16. Comparison of the EORTC criteria and PERCIST in solid tumors: a pooled analysis and review.

    Science.gov (United States)

    Kim, Jung Han

    2016-09-06

    Two sets of response criteria using PET are currently available to monitor metabolic changes in solid tumors: the criteria developed by the European Organization for Research and Treatment of Cancer (EORTC criteria) and the PET Response Criteria in Solid Tumors (PERCIST). We conducted this pooled study to investigate the strength of agreement between the EORTC criteria and PERCIST in the assessment of tumor response. We surveyed MEDLINE, EMBASE and PUBMED for articles with terms of the EORTC criteria and PERCIST between 2009 and January 2016. We searched for all the references of relevant articles and reviews using the 'related articles' feature in the PUBMED. There were six articles with the data on the comparison of the EORTC criteria and PERCIST. A total of 348 patients were collected; 190 (54.6%) with breast cancer, 81 with colorectal cancer, 45 with lung cancer, 14 with basal cell carcinoma in the skin, 12 with stomach cancer, and 6 with head and neck cancer. The agreement of tumor response between the EORTC criteria and PERCIST was excellent (k = 0.946). Of 348 patients, only 12 (3.4%) showed disagreement between the two criteria in the assessment of tumor response. The shift of tumor response between the EORTC criteria and PERCIST occurred mostly in patients with PMR and SMD. The estimated overall response rates were not significantly different between the two criteria (72.7% by EORTC vs. 73.6% by PERCIST). In conclusion, this pooled analysis demonstrates that the EORTC criteria and PERCIST showed almost perfect agreement in the assessment of tumor response.

  17. Comparison of the EORTC criteria and PERCIST in solid tumors: a pooled analysis and review

    Science.gov (United States)

    Kim, Jung Han

    2016-01-01

    Two sets of response criteria using PET are currently available to monitor metabolic changes in solid tumors: the criteria developed by the European Organization for Research and Treatment of Cancer (EORTC criteria) and the PET Response Criteria in Solid Tumors (PERCIST). We conducted this pooled study to investigate the strength of agreement between the EORTC criteria and PERCIST in the assessment of tumor response. We surveyed MEDLINE, EMBASE and PUBMED for articles with terms of the EORTC criteria and PERCIST between 2009 and January 2016. We searched for all the references of relevant articles and reviews using the ‘related articles’ feature in the PUBMED. There were six articles with the data on the comparison of the EORTC criteria and PERCIST. A total of 348 patients were collected; 190 (54.6%) with breast cancer, 81 with colorectal cancer, 45 with lung cancer, 14 with basal cell carcinoma in the skin, 12 with stomach cancer, and 6 with head and neck cancer. The agreement of tumor response between the EORTC criteria and PERCIST was excellent (k = 0.946). Of 348 patients, only 12 (3.4%) showed disagreement between the two criteria in the assessment of tumor response. The shift of tumor response between the EORTC criteria and PERCIST occurred mostly in patients with PMR and SMD. The estimated overall response rates were not significantly different between the two criteria (72.7% by EORTC vs. 73.6% by PERCIST). In conclusion, this pooled analysis demonstrates that the EORTC criteria and PERCIST showed almost perfect agreement in the assessment of tumor response. PMID:27517621

  18. Comparison of performance of the 2016 ACR-EULAR classification criteria for primary Sjögren's syndrome with other sets of criteria in Japanese patients.

    Science.gov (United States)

    Tsuboi, Hiroto; Hagiwara, Shinya; Asashima, Hiromitsu; Takahashi, Hiroyuki; Hirota, Tomoya; Noma, Hisashi; Umehara, Hisanori; Kawakami, Atsushi; Nakamura, Hideki; Sano, Hajime; Tsubota, Kazuo; Ogawa, Yoko; Takamura, Etsuko; Saito, Ichiro; Inoue, Hiroko; Nakamura, Seiji; Moriyama, Masafumi; Takeuchi, Tsutomu; Tanaka, Yoshiya; Hirata, Shintaro; Mimori, Tsuneyo; Matsumoto, Isao; Sumida, Takayuki

    2017-03-22

    To compare the performance of the new 2016 American College of Rheumatology (ACR)-European League Against Rheumatism (EULAR) classification criteria for primary Sjögren's syndrome (SS) with 1999 revised Japanese Ministry of Health criteria for diagnosis of SS (JPN), 2002 American-European Consensus Group classification criteria for SS (AECG) and 2012 ACR classification criteria for SS (ACR) in Japanese patients. The study subjects were 499 patients with primary SS (pSS) or suspected pSS who were followed up in June 2012 at 10 hospitals in Japan. All patients had been assessed for all four criteria of JPN (pathology, oral, ocular, anti-SS-A/SS-B antibodies). The clinical diagnosis by the physician in charge was set as the 'gold standard'. pSS was diagnosed in 302 patients and ruled out in 197 patients by the physician in charge. The sensitivity of the ACR-EULAR criteria in the diagnosis of pSS (95.4%) was higher than those of the JPN, AECG and ACR (82.1%, 89.4% and 79.1%, respectively), while the specificity of the ACR-EULAR (72.1%) was lower than those of the three sets (90.9%, 84.3% and 84.8%, respectively). The differences of sensitivities and specificities between the ACR-EULAR and other three sets of criteria were statistically significant (pEULAR criteria, compared with none of the other three sets. The ACR-EULAR criteria had significantly higher sensitivity and lower specificity in diagnosis of pSS, compared with the currently available three sets of criteria. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  19. Biological Aging - Criteria for Modeling and a New Mechanistic Model

    Science.gov (United States)

    Pletcher, Scott D.; Neuhauser, Claudia

    To stimulate interaction and collaboration across scientific fields, we introduce a minimum set of biological criteria that theoretical models of aging should satisfy. We review results of several recent experiments that examined changes in age-specific mortality rates caused by genetic and environmental manipulation. The empirical data from these experiments is then used to test mathematical models of aging from several different disciplines, including molecular biology, reliability theory, physics, and evolutionary biology/population genetics. We find that none of the current models are consistent with all of the published experimental findings. To provide an example of how our criteria might be applied in practice, we develop a new conceptual model of aging that is consistent with our observations.

  20. ACR appropriateness criteria radiologic management of infected fluid collections.

    Science.gov (United States)

    Lorenz, Jonathan M; Al-Refaie, Waddah B; Cash, Brooks D; Gaba, Ron C; Gervais, Debra A; Gipson, Matthew G; Kolbeck, Kenneth J; Kouri, Brian E; Marshalleck, Francis E; Nair, Ajit V; Ray, Charles E; Hohenwalter, Eric J

    2015-08-01

    The best management of infected fluid collections depends on a careful assessment of clinical and anatomic factors as well as an up-to-date review of the published literature, to be able to select from a host of multidisciplinary treatment options. This article reviews conservative, radiologic, endoscopic, and surgical options and their best application to infected fluid collections as determined by the ACR Appropriateness Criteria Expert Panel on Interventional Radiology. The ACR Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed every three years by a multidisciplinary expert panel. The guideline development and review include an extensive analysis of current medical literature from peer-reviewed journals, and the application, by the panel, of a well-established consensus methodology (modified Delphi) to rate the appropriateness of imaging and treatment procedures. In those instances in which evidence is lacking or not definitive, expert opinion may be used to recommend imaging or treatment.

  1. MCO combustible gas management leak test acceptance criteria

    Energy Technology Data Exchange (ETDEWEB)

    SHERRELL, D.L.

    1999-05-11

    Existing leak test acceptance criteria for mechanically sealed and weld sealed multi-canister overpacks (MCO) were evaluated to ensure that MCOs can be handled and stored in stagnant air without compromising the Spent Nuclear Fuel Project's overall strategy to prevent accumulation of combustible gas mixtures within MCO's or within their surroundings. The document concludes that the integrated leak test acceptance criteria for mechanically sealed and weld sealed MCOs (1 x 10{sup -5} std cc/sec and 1 x 10{sup -7} std cc/sec, respectively) are adequate to meet all current and foreseeable needs of the project, including capability to demonstrate compliance with the NFPA 60 Paragraph 3-3 requirement to maintain hydrogen concentrations [within the air atmosphere CSB tubes] t or below 1 vol% (i.e., at or below 25% of the LFL).

  2. Establishment of noise acceptance criteria for wind turbines

    Science.gov (United States)

    Stephens, D. G.; Shepherd, K. P.; Grosveld, F.

    1981-01-01

    A program is being conducted to develop noise criteria for wind turbines which minimize annoyance and which can be used in design specifications for future machines. The approach consists of presenting wind turbine noise stimuli to test subjects in a laboratory listening chamber. The responses of the subjects are recorded for a range of stimuli which encompass the designs, operating conditions, and ambient noise levels of current and future installations. Results to date have established the threshold of detectability for a range of impulsive stimuli of the type associated with blade/tower-wake interactions. The status of the ongoing psychoacoustic tests, the subjective data, and the approach to the development of noise acceptance criteria are described.

  3. MANOVA, LDA, and FA criteria in clusters parameter estimation

    Directory of Open Access Journals (Sweden)

    Stan Lipovetsky

    2015-12-01

    Full Text Available Multivariate analysis of variance (MANOVA and linear discriminant analysis (LDA apply such well-known criteria as the Wilks’ lambda, Lawley–Hotelling trace, and Pillai’s trace test for checking quality of the solutions. The current paper suggests using these criteria for building objectives for finding clusters parameters because optimizing such objectives corresponds to the best distinguishing between the clusters. Relation to Joreskog’s classification for factor analysis (FA techniques is also considered. The problem can be reduced to the multinomial parameterization, and solution can be found in a nonlinear optimization procedure which yields the estimates for the cluster centers and sizes. This approach for clustering works with data compressed into covariance matrix so can be especially useful for big data.

  4. Current Titles

    Energy Technology Data Exchange (ETDEWEB)

    Various

    2006-06-01

    This booklet is published for those interested in current research being conducted at the National Center for Electron Microscopy. The NCEM is a DOE-designated national user facility and is available at no charge to qualified researchers. Access is controlled by an external steering committee. Interested researchers may contact Jane Cavlina, Administrator, at 510/486-6036.

  5. Diagnostic criteria of familial Mediterranean fever.

    Science.gov (United States)

    Berkun, Yackov; Eisenstein, Eli M

    2014-01-01

    Familial Mediterranean fever (FMF) is the most prevalent monogenic autoinflammatory disease, mainly affecting ethnic groups living at Mediterranean basin. FMF is characterized by recurrent, self-limited episodes of fever and serositis. The diagnosis is difficult in the presence of atypical signs, which may result in significant delay in initiating treatment. As autoinflammatory diseases may have overlapping symptoms, strict diagnostic criteria are essential. Since the discovery that mutations in the gene MEFV underlie FMF, molecular genetic testing has been used as a diagnostic adjunct, especially in atypical cases. However, despite progress in the understanding of FMF disease mechanisms during the past 15 years; the diagnosis is still based on clinical criteria. Several sets of diagnostic criteria have been proposed and used. Existing diagnostic criteria should be modified to include genetic data, and need to be more widely validated. Copyright © 2014 Elsevier B.V. All rights reserved.

  6. APPLICATION OF DECISION THEORY BASED CRITERIA FOR ...

    African Journals Online (AJOL)

    2012-11-03

    Nov 3, 2012 ... STRUCTURAL APPRAISAL OF A BUILDING DURING ... probabilistic model, decision theory based criteria, target value, uncommon accidents, collapse. 1. Introduction ... about some aspect of the design or construction, in-.

  7. Generalized Lawson Criteria for Inertial Confinement Fusion

    Energy Technology Data Exchange (ETDEWEB)

    Tipton, Robert E. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2015-08-27

    The Lawson Criterion was proposed by John D. Lawson in 1955 as a general measure of the conditions necessary for a magnetic fusion device to reach thermonuclear ignition. Over the years, similar ignition criteria have been proposed which would be suitable for Inertial Confinement Fusion (ICF) designs. This paper will compare and contrast several ICF ignition criteria based on Lawson’s original ideas. Both analytical and numerical results will be presented which will demonstrate that although the various criteria differ in some details, they are closely related and perform similarly as ignition criteria. A simple approximation will also be presented which allows the inference of each ignition parameter directly from the measured data taken on most shots fired at the National Ignition Facility (NIF) with a minimum reliance on computer simulations. Evidence will be presented which indicates that the experimentally inferred ignition parameters on the best NIF shots are very close to the ignition threshold.

  8. Work Criteria Function of Irreversible Heat Engines

    Directory of Open Access Journals (Sweden)

    Mahmoud Huleihil

    2014-01-01

    Full Text Available The irreversible heat engine is reconsidered with a general heat transfer law. Three criteria known in the literature—power, power density, and efficient power—are redefined in terms of the work criteria function (WCF, a concept introduced in this study. The formulation enabled the suggestion and analysis of a unique criterion—the efficient power density (which accounts for the efficiency and power density. Practically speaking, the efficient power and the efficient power density could be defined on any order based on the WCF. The applicability of the WCF is illustrated for the Newtonian heat transfer law (n=1 and for the radiative law (n=4. The importance of WCF is twofold: it gives an explicit design and educational tool to analyze and to display graphically the different criteria side by side and thus helps in design process. Finally, the criteria were compared and some conclusions were drawn.

  9. Multi-Criteria Optimization for Image Guidance

    CERN Document Server

    Winey, Brian

    2011-01-01

    Purpose: To develop a multi-criteria optimization framework for image guided radiotherapy. Methods: An algorithm is proposed for a multi-criteria framework for the purpose of patient setup verification decision processes. Optimal patient setup shifts and rotations are not always straightforward, particularly for deformable or moving targets of the spine, abdomen, thorax, breast, head and neck and limbs. The algorithm relies upon dosimetric constraints and objectives to aid in the patient setup such that the patient is setup to maximize tumor dose coverage and minimize dose to organs at risk while allowing for daily clinical changes. A simple 1D model and a lung lesion are presented. Results: The algorithm delivers a multi-criteria optimization framework allowing for clinical decisions to accommodate patient target variation make setup decisions less straightforward. With dosimetric considerations, optimal patient positions can be derived. Conclusions: A multi-criteria framework is demonstrated to aid in the p...

  10. Ebook Evaluation Criteria: A Proposed Checklist

    Directory of Open Access Journals (Sweden)

    Amir Ghaebi

    2010-09-01

    Full Text Available E-books embody diverse features, each of which could contribute towards increasing their user-agreeability and attracting more users. In order to select an Ebook best suited to their needs, both users and librarians consider a set of criteria. The present study aims at providing the evaluation criteria from the standpoint of both the users and librarys by employing two approaches, i.e. through considering the characteristics of the electronic environment, and also maintaining the desired features of the printed media in E-books. By reviewing the resources published in the field of E-books, 15 criteria along with 101 components have been collectively discussed for evaluation of the suitable E-book for users and libraries. Four criteria with 24 components have been solely devised for libraries and librarians.

  11. Relaxation Criteria for Iterated Traffic Simulations

    Science.gov (United States)

    Kelly, Terence; Nagel, Kai

    Iterative transportation microsimulations adjust traveler route plans by iterating between a microsimulation and a route planner. At each iteration, the route planner adjusts individuals' route choices based on the preceding microsimulations. Empirically, this process yields good results, but it is usually unclear when to stop the iterative process when modeling real-world traffic. This paper investigates several criteria to judge relaxation of the iterative process, emphasizing criteria related to traveler decision-making.

  12. Criteria for universality of quantum gates

    Science.gov (United States)

    Sawicki, Adam; Karnas, Katarzyna

    2017-06-01

    We consider the problem of deciding if a set of quantum one-qudit gates S ={U1,...,Un} is universal. We provide the compact-form criteria leading to a simple algorithm that allows deciding the universality of any given set of gates in a finite number of steps. Moreover, for a nonuniversal S our criteria indicate what types of gates can be added to S to turn it into a universal set.

  13. Natural phenomena hazards site characterization criteria

    Energy Technology Data Exchange (ETDEWEB)

    1994-03-01

    The criteria and recommendations in this standard shall apply to site characterization for the purpose of mitigating Natural Phenomena Hazards (wind, floods, landslide, earthquake, volcano, etc.) in all DOE facilities covered by DOE Order 5480.28. Criteria for site characterization not related to NPH are not included unless necessary for clarification. General and detailed site characterization requirements are provided in areas of meteorology, hydrology, geology, seismology, and geotechnical studies.

  14. Full Spectrum Crashworthiness Criteria for Rotorcraft

    Science.gov (United States)

    2011-12-01

    C0-C1). The maximum Nij Full Spectrum Crashworthiness Criteria October 2011 Page 97 as measured at the cervical vertebrae (C7-T1) is 1.5 (Table...regions including the head, neck, cervical spine, upper extremities, thorax, abdomen, thoracic lumbar spine, lower extremities, and general. The body...injury mechanisms, such as fractured vertebra , ruptured spleen, or lower leg fracture are not included. Full Spectrum Crashworthiness Criteria

  15. AAPT Diagnostic Criteria for Central Neuropathic Pain.

    Science.gov (United States)

    Widerström-Noga, Eva; Loeser, John D; Jensen, Troels Staehelin; Finnerup, Nanna Brix

    2017-06-27

    Central neuropathic pain, which is pain caused by a lesion or disease of the central somatosensory nervous system, is a serious consequence of spinal cord injury, stroke, multiple sclerosis, and other conditions affecting the central nervous system. A collaborative effort between the Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks public-private partnership and the American Pain Society, the Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks-American Pain Society Pain Taxonomy (AAPT) initiative, invited a working group to develop diagnostic criteria for central neuropathic pain. The criteria for central neuropathic pain that were developed expand upon existing criteria for neuropathic pain and the International Classification of Diseases 11th Revision draft criteria to ensure consistency. This article focuses on central neuropathic pain associated with spinal cord injury, stroke, and multiple sclerosis, but the AAPT framework can be extended to central pain due to other causes such as traumatic brain injury. The classification of central neuropathic pain is organized according to the AAPT multidimensional framework, specifically: 1) core diagnostic criteria, 2) common features, 3) common medical and psychiatric comorbidities, 4) neurobiological, psychosocial, and functional consequences, and 5) putative neurobiological and psychosocial mechanisms, risk factors, and protective factors. The AAPT chronic central neuropathic pain taxonomy provides a classification for central pain associated with spinal cord injury, stroke, and multiple sclerosis. The diagnostic criteria are organized according to the AAPT multidimensional framework, specifically: 1) core diagnostic criteria, 2) common features, 3) common medical and psychiatric comorbidities, 4) neurobiological, psychosocial, and functional consequences, and 5) putative neurobiological and psychosocial

  16. Current titles

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-07-01

    This booklet is published for those interested in current research being conducted at the National Center for Electron Microscopy. The NCEM is a DOE-designated national user facility and is available at no charge to qualified researchers. Access is controlled by an external steering committee. Interested researchers may contact Gretchen Hermes at (510) 486-5006 or address below for a User`s Guide. Copies of available papers can be ordered from: Theda Crawford National Center for Electron Microscopy, Lawrence Berkeley Laboratory, One Cyclotron Rd., MS72, Berkeley, California, USA 94720.

  17. Photovoltaic system criteria documents. Volume 3: Environmental issues and evaluation criteria for photovoltaic applications

    Science.gov (United States)

    Koenig, John C.; Billitti, Joseph W.; Tallon, John M.

    1979-01-01

    The environmental issues and evaluation criteria relating to the suitability of sites proposed for photovoltaic (PV) system deployment are identified. The important issues are defined, briefly discussed and then developed into evaluation criteria. System designers are provided with information on the environmental sensitivity of PV systems in realistic applications, background material which indicates the applicability of the siting issues identified, and evaluation criteria are defined to facilitate the selection of sites that maximize PV system operation.

  18. Beyond the security paradox: Ten criteria for a socially informed security policy.

    Science.gov (United States)

    Pavone, Vincenzo; Ball, Kirstie; Degli Esposti, Sara; Dibb, Sally; Santiago-Gómez, Elvira

    2017-04-01

    This article investigates the normative and procedural criteria adopted by European citizens to assess the acceptability of surveillance-oriented security technologies. It draws on qualitative data gathered at 12 citizen summits in nine European countries. The analysis identifies 10 criteria, generated by citizens themselves, for a socially informed security policy. These criteria not only reveal the conditions, purposes and operation rules that would make current European security policies and technologies more consistent with citizens' priorities. They also cast light on an interesting paradox: although people feel safe in their daily lives, they believe security could, and should, be improved.

  19. Conceptual design criteria for facilities for geologic disposal of radioactive wastes in salt formations

    Energy Technology Data Exchange (ETDEWEB)

    1977-01-01

    The facility design requirements and criteria discussed are: general codes, standards, specifications, and regulations; site criteria; land improvements criteria, low-level waste facility criteria; canistered waste facility criteria; support facilities criteria; and utilities and services criteria. (LK)

  20. EULAR points to consider in the development of classification and diagnostic criteria in systemic vasculitis

    DEFF Research Database (Denmark)

    Basu, Neil; Watts, Richard; Bajema, Ingeborg;

    2010-01-01

    The systemic vasculitides are multiorgan diseases where early diagnosis and treatment can significantly improve outcomes. Robust nomenclature reduces diagnostic delay. However, key aspects of current nomenclature are widely perceived to be out of date, these include disease definitions, classific......, classification and diagnostic criteria. Therefore, the aim of the present work was to identify deficiencies and provide contemporary points to consider for the development of future definitions and criteria in systemic vasculitis....

  1. How reliable are the Rome III criteria for the assessment of functional gastrointestinal disorders in children?

    Science.gov (United States)

    Chogle, Ashish; Dhroove, Gati; Sztainberg, Marcelo; Di Lorenzo, Carlo; Saps, Miguel

    2010-12-01

    Functional gastrointestinal disorders (FGIDs) are common in children. Diagnosis of these conditions is based on the pediatric Rome criteria. In the past, we have shown that there was low inter-rater reliability (IRR) among pediatric gastroenterologists using the Rome II criteria. Since then, a new version of the criteria has been issued. The reliability of the Rome III criteria has not been established. A total of 10 pediatric gastroenterologist specialists and 10 pediatric gastroenterology fellows were provided with 20 clinical vignettes and a list of 17 possible diagnoses (all pediatric categories of the Rome criteria plus "none of the above" or "not enough information") and instructed to select one or more diagnosis for each vignette. The average percentage of agreement among the raters was 50% for the pediatric gastroenterologists and 45% for the pediatric gastroenterology fellows. The inter-rater percentage of agreement per clinical case was >50% in only 7 out of 20 (35%) vignettes for the gastroenterologists and only 6 out of 20 (30%) cases for the fellows. The inter-rater percentage of agreement was Rome III criteria. Only slight to fair agreement between raters existed for important subcategories of pain and constipation. The results from our current study are almost similar to that of the IRR study done for the Rome II criteria. This indicates the need for further refinement of the Rome criteria to make them more encompassing and user friendly.

  2. Appropriate criteria set for personnel promotion across organizational levels using analytic hierarchy process (AHP

    Directory of Open Access Journals (Sweden)

    Charles Noven Castillo

    2017-01-01

    Full Text Available Currently, there has been limited established specific set of criteria for personnel promotion to each level of the organization. This study is conducted in order to develop a personnel promotion strategy by identifying specific sets of criteria for each level of the organization. The complexity of identifying the criteria set along with the subjectivity of these criteria require the use of multi-criteria decision-making approach particularly the analytic hierarchy process (AHP. Results show different sets of criteria for each management level which are consistent with several frameworks in literature. These criteria sets would help avoid mismatch of employee skills and competencies and their job, and at the same time eliminate the issues in personnel promotion such as favouritism, glass ceiling, and gender and physical attractiveness preference. This work also shows that personality and traits, job satisfaction and experience and skills are more critical rather than social capital across different organizational levels. The contribution of this work is in identifying relevant criteria in developing a personnel promotion strategy across organizational levels.

  3. The potential impact of new diagnostic criteria on the frequency of gestational diabetes mellitus in Sweden.

    Science.gov (United States)

    Claesson, Rickard; Ekelund, Magnus; Berntorp, Kerstin

    2013-10-01

    The International Association of Diabetes and Pregnancy Study Groups (IADPSG) has suggested new diagnostic criteria for gestational diabetes mellitus. Many centers in Europe still use the World Health Organization (WHO) criteria. In southern Sweden we use the 2-h threshold of the European Association for the Study of Diabetes criteria based on universal screening with a 75-g oral glucose tolerance test. We have retrospectively scrutinized oral glucose tolerance tests in a subset of 174 women included in a previous study, diagnosed with gestational diabetes mellitus 1996-1999. A complete repeat oral glucose tolerance test was performed directly after diagnosis in 120 women. When applying the current Swedish criteria, and the IADPSG and the WHO criteria to the material, gestational diabetes mellitus was confirmed in 67% (80/120), 84% (101/120), and 80% (96/120), respectively. Hence, 26% (101/80) more women were identified by the IADPSG criteria and 20% (96/80) more women by the WHO criteria, compared with the criteria presently in use.

  4. Current ornithology

    CERN Document Server

    1983-01-01

    The appearance of the first volume of a projected series is the occasion for comment on scope, aims, and genesis of the work. The scope of Current Ornithology is all of the biology of birds. Ornithology, as a whole-organism science, is concerned with birds at every level of bi­ ological organization, from the molecular to the community, at least from the Jurassic to the present time, and over every scholarly discipline in which bird biology is done; to say this is merely to expand a dic­ tionary definition of "ornithology. " The aim of the work, to be realized over several volumes, is to present reviews or position statements con­ cerning the active fields of ornithological research. The reviews will be relatively short, and often will be done from the viewpoint of a readily­ identified group or school. Such a work could have come into being at any time within the past fifty years, but that Current Ornithology appears now is a result of events that are only seven to eight years old. One important event wa...

  5. Research progress on criteria for discontinuation of EGFR inhibitor therapy

    Directory of Open Access Journals (Sweden)

    Zhuang HQ

    2012-10-01

    Full Text Available Hong-qing Zhuang, Zhi-yong Yuan, Jun Wang, Ping Wang, Lu-jun Zhao, Bai-lin ZhangDepartment of Radiotherapy, Tianjin Medical University Cancer Institute and Hospital, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin Lung Cancer Center, Tianjin, People's Republic of ChinaAbstract: The clinical success of the epidermal growth factor receptor (EGFR tyrosine kinase inhibitors (TKI as therapeutic agents has prompted great interest in their further development and clinical testing for a wide variety of malignancies. However, most studies have focused on the efficacy of TKI, and few studies have been done on the criteria for their discontinuation. The current standard for drug discontinuation is “until progression”, based on change in tumor size. However, tumor size is not related to the gene expression which determines the efficacy of TKI in the final analysis, and it is also difficult to make a thorough and correct prediction based on tumor size when the TKI is discontinued. Nevertheless, clinical evaluation of the criteria for TKI discontinuation is still in its early days. Some promising findings have started to emerge. With the improving knowledge of EGFR and its inhibitors, it is expected that the criteria for discontinuation of EGFR inhibitor therapy will become clearer.Keywords: epidermal growth factor receptor, drug discontinuation, acquired drug-resistance

  6. Recommended Diagnostic Criteria for Occupational Chronic Lead Poisoning

    Institute of Scientific and Technical Information of China (English)

    SUNJIN-BAI; WANGJIN-PING

    1995-01-01

    The present study aims to recommend the normal upper limit,the acceptable upper limit,the subclinical lead absorption and intoxication diagnostic criteria in an effort to re-evaluate the current national diagnostic criteria for the occupational chronic lead poisoning.The study was conducted on 330 lead exposed workers and 100 non-exposed controls based on the determination of blood and urinary lead,porphyrin metabolism indices,as well as other indices under a nationwide quality control program.The data were subsequently treated by the curve fitting,multi-step transformation to Gauss distribution,and discriminant analysis with the aid of a SAS software package.The relationships between the air lead and blood lead level with certain biological parameters indicative of excessive lead exposure and poisoning were well established.The sensitivity,specificity,accuracy,false positive and false negative results of these critical values were also fully evaluated.This study would be useful for the amendment of the new edition of the national diagnostic criteria for the occupational chronic lead poisoning in China and would provide new approaches for similar investigations.

  7. Empirical testing of criteria for dissociative schizophrenia.

    Science.gov (United States)

    Laferrière-Simard, Marie-Christine; Lecomte, Tania; Ahoundova, Lola

    2014-01-01

    This study examined the validity of dissociative schizophrenia diagnostic criteria. In the first phase, 50 participants with a psychotic disorder were administered the Dissociative Experiences Scale and the Childhood Trauma Questionnaire to identify those with dissociative characteristics. In the second phase, we selected those who had a score of 15 or above on the Dissociative Experiences Scale. Fifteen of these participants were evaluated thoroughly with the Structured Clinical Interview for DSM-IV Axis I, Structured Clinical Interview for DSM-IV Axis II, and Structured Clinical Interview for DSM-IV Dissociative Disorders to determine whether they met the criteria for dissociative schizophrenia and to generate a clinical description. Our results indicated that 24% of the individuals we tested met these criteria. We propose making mandatory 1 of the 3 dissociative symptoms of the criteria to eliminate people with only nonspecific symptoms (e.g., extensive comorbidity). According to this modified criterion, 14% of our sample would receive a diagnosis of dissociative schizophrenia. However, a more comprehensive look at the clinical picture begs the question of whether dissociative schizophrenia is truly present in every person meeting the criteria. We discuss the relevance of creating a new schizophrenia subtype and offer recommendations for clinicians.

  8. ACR Appropriateness Criteria Review ACR Appropriateness Criteria® Occupational Lung Diseases.

    Science.gov (United States)

    Bacchus, Leon; Shah, Rakesh D; Chung, Jonathan H; Crabtree, Traves P; Heitkamp, Darel E; Iannettoni, Mark D; Johnson, Geoffrey B; Jokerst, Clinton; McComb, Barbara L; Saleh, Anthony G; Steiner, Robert M; Mohammed, Tan-Lucien H; Ravenel, James G

    2016-01-01

    Occupational lung disease is a category of disease entities characterized by a reaction of the lung parenchyma to inhaled aerosolized particles found in the environment. This document summarizes the imaging appropriateness data for silicosis, coal worker pneumoconiosis, and asbestosis. The main points of the document are that computed tomography is more sensitive than radiography, computed tomography without contrast generally suffices for evaluation, and fluorodeoxyglucose-positron emission tomography may have utility in patients with mesothelioma. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed every 3 years by a multidisciplinary expert panel. The guideline development and review includes an extensive analysis of current medical literature from peer-reviewed journals and the application of a well-established consensus methodology (modified Delphi) to rate the appropriateness of imaging and treatment procedures by the panel. In those instances in which evidence is lacking or not definitive, expert opinion may be used to recommend imaging or treatment.

  9. DFIG Harmonic Current Controlling with the Grid Low Harmonic Voltage

    Directory of Open Access Journals (Sweden)

    Huan Wang

    2014-01-01

    Full Text Available This study presents a vector control strategy based on stator harmonic current closed-loop, it adds individually the control loop about of each stator harmonic current to restrain the stator harmonic current, in order to meet the THD criteria. The control strategy of restraining the harmonic current presents the design of the stator harmonic current restrains the current controller. It influences the rotor voltage of the stator harmonic current restraining strategies.

  10. CisLunar Habitat Internal Architecture Design Criteria

    Science.gov (United States)

    Jones, R.; Kennedy, K.; Howard, R.; Whitmore, M.; Martin, C.; Garate, J.

    2017-01-01

    BACKGROUND: In preparation for human exploration to Mars, there is a need to define the development and test program that will validate deep space operations and systems. In that context, a Proving Grounds CisLunar habitat spacecraft is being defined as the next step towards this goal. This spacecraft will operate differently from the ISS or other spacecraft in human history. The performance envelope of this spacecraft (mass, volume, power, specifications, etc.) is being defined by the Future Capabilities Study Team. This team has recognized the need for a human-centered approach for the internal architecture of this spacecraft and has commissioned a CisLunar Phase-1 Habitat Internal Architecture Study Team to develop a NASA reference configuration, providing the Agency with a "smart buyer" approach for future acquisition. THE CISLUNAR HABITAT INTERNAL ARCHITECTURE STUDY: Overall, the CisLunar Habitat Internal Architecture study will address the most significant questions and risks in the current CisLunar architecture, habitation, and operations concept development. This effort is achieved through definition of design criteria, evaluation criteria and process, design of the CisLunar Habitat Phase-1 internal architecture, and the development and fabrication of internal architecture concepts combined with rigorous and methodical Human-in-the-Loop (HITL) evaluations and testing of the conceptual innovations in a controlled test environment. The vision of the CisLunar Habitat Internal Architecture Study is to design, build, and test a CisLunar Phase-1 Habitat Internal Architecture that will be used for habitation (e.g. habitability and human factors) evaluations. The evaluations will mature CisLunar habitat evaluation tools, guidelines, and standards, and will interface with other projects such as the Advanced Exploration Systems (AES) Program integrated Power, Avionics, Software (iPAS), and Logistics for integrated human-in-the-loop testing. The mission of the Cis

  11. Development of structural design criteria for ITER.

    Energy Technology Data Exchange (ETDEWEB)

    Majumdar, S.

    1998-06-22

    The irradiation environment experienced by the in-vessel components of fusion reactors such as HER presents structural design challenges not envisioned in the development of existing structural design criteria such as the ASME Code or RCC-MR. From the standpoint of design criteria, the most significant issues stem from the irradiation-induced changes in material properties, specifically the reduction of ductility, strain hardening capability, and fracture toughness with neutron irradiation. Recently, Draft 7 of the interim ITER structural design criteria (ISDC), which provide new rules for guarding against such problems, was released for trial use by the ITER designers. The new rules, which were derived from a simple model based on the concept of elastic follow up factor, provide primary and secondary stress limits as functions of uniform elongation and ductility. The implication of these rules on the allowable surface heat flux on typical first walls made of type 316 stainless steel and vanadium alloys are discussed.

  12. Developing Criteria to Establish Trusted Digital Repositories

    Directory of Open Access Journals (Sweden)

    John Faundeen

    2017-04-01

    Full Text Available This paper details the drivers, methods, and outcomes of the U.S. Geological Survey’s quest to establish criteria by which to judge its own digital preservation resources as Trusted Digital Repositories. Drivers included recent U.S. legislation focused on data and asset management conducted by federal agencies spending $100M USD or more annually on research activities. The methods entailed seeking existing evaluation criteria from national and international organizations such as International Standards Organization (ISO, U.S. Library of Congress, and Data Seal of Approval upon which to model USGS repository evaluations. Certification, complexity, cost, and usability of existing evaluation models were key considerations. The selected evaluation method was derived to allow the repository evaluation process to be transparent, understandable, and defensible; factors that are critical for judging competing, internal units. Implementing the chosen evaluation criteria involved establishing a cross-agency, multi-disciplinary team that interfaced across the organization.

  13. Statistical criteria for characterizing irradiance time series.

    Energy Technology Data Exchange (ETDEWEB)

    Stein, Joshua S.; Ellis, Abraham; Hansen, Clifford W.

    2010-10-01

    We propose and examine several statistical criteria for characterizing time series of solar irradiance. Time series of irradiance are used in analyses that seek to quantify the performance of photovoltaic (PV) power systems over time. Time series of irradiance are either measured or are simulated using models. Simulations of irradiance are often calibrated to or generated from statistics for observed irradiance and simulations are validated by comparing the simulation output to the observed irradiance. Criteria used in this comparison should derive from the context of the analyses in which the simulated irradiance is to be used. We examine three statistics that characterize time series and their use as criteria for comparing time series. We demonstrate these statistics using observed irradiance data recorded in August 2007 in Las Vegas, Nevada, and in June 2009 in Albuquerque, New Mexico.

  14. Developing criteria to establish Trusted Digital Repositories

    Science.gov (United States)

    Faundeen, John L.

    2017-01-01

    This paper details the drivers, methods, and outcomes of the U.S. Geological Survey’s quest to establish criteria by which to judge its own digital preservation resources as Trusted Digital Repositories. Drivers included recent U.S. legislation focused on data and asset management conducted by federal agencies spending $100M USD or more annually on research activities. The methods entailed seeking existing evaluation criteria from national and international organizations such as International Standards Organization (ISO), U.S. Library of Congress, and Data Seal of Approval upon which to model USGS repository evaluations. Certification, complexity, cost, and usability of existing evaluation models were key considerations. The selected evaluation method was derived to allow the repository evaluation process to be transparent, understandable, and defensible; factors that are critical for judging competing, internal units. Implementing the chosen evaluation criteria involved establishing a cross-agency, multi-disciplinary team that interfaced across the organization. 

  15. ACR appropriateness criteria: Permanent source brachytherapy for prostate cancer.

    Science.gov (United States)

    Davis, Brian J; Taira, Al V; Nguyen, Paul L; Assimos, Dean G; D'Amico, Anthony V; Gottschalk, Alexander R; Gustafson, Gary S; Keole, Sameer R; Liauw, Stanley L; Lloyd, Shane; McLaughlin, Patrick W; Movsas, Benjamin; Prestidge, Bradley R; Showalter, Timothy N; Vapiwala, Neha

    To provide updated American College of Radiology (ACR) appropriateness criteria for transrectal ultrasound-guided transperineal interstitial permanent source brachytherapy. The ACR appropriateness criteria are evidence-based guidelines for specific clinical conditions that are reviewed every 3 years by a multidisciplinary expert panel. The guideline development and review include an extensive analysis of current medical literature from peer reviewed journals and the application of a well-established consensus methodology (modified Delphi) to rate the appropriateness of imaging and treatment procedures by the panel. In those instances where evidence is lacking or not definitive, expert opinion may be used to recommend imaging or treatment. Permanent prostate brachytherapy (PPB) is a treatment option for appropriately selected patients with localized prostate cancer with low to very high risk disease. PPB monotherapy remains an appropriate and effective curative treatment for low-risk prostate cancer patients demonstrating excellent long-term cancer control and acceptable morbidity. PPB monotherapy can be considered for select intermediate-risk patients with multiparametric MRI useful in evaluation of such patients. High-risk patients treated with PPB should receive supplemental external beam radiotherapy (EBRT) along with androgen deprivation. Similarly, patients with involved pelvic lymph nodes may also be considered for such combined treatment but reported long-term outcomes are limited. Computed tomography-based postimplant dosimetry completed within 60 days of PPB is essential for quality assurance. PPB may be considered for treatment of local recurrence after EBRT but is associated with an increased risk of toxicity. Updated appropriateness criteria for patient evaluation, selection, treatment, and postimplant dosimetry are given. These criteria are intended to be advisory only with the final responsibility for patient care residing with the treating

  16. Establishing endangered species recovery criteria using predictive simulation modeling

    Science.gov (United States)

    McGowan, Conor P.; Catlin, Daniel H.; Shaffer, Terry L.; Gratto-Trevor, Cheri L.; Aron, Carol

    2014-01-01

    Listing a species under the Endangered Species Act (ESA) and developing a recovery plan requires U.S. Fish and Wildlife Service to establish specific and measurable criteria for delisting. Generally, species are listed because they face (or are perceived to face) elevated risk of extinction due to issues such as habitat loss, invasive species, or other factors. Recovery plans identify recovery criteria that reduce extinction risk to an acceptable level. It logically follows that the recovery criteria, the defined conditions for removing a species from ESA protections, need to be closely related to extinction risk. Extinction probability is a population parameter estimated with a model that uses current demographic information to project the population into the future over a number of replicates, calculating the proportion of replicated populations that go extinct. We simulated extinction probabilities of piping plovers in the Great Plains and estimated the relationship between extinction probability and various demographic parameters. We tested the fit of regression models linking initial abundance, productivity, or population growth rate to extinction risk, and then, using the regression parameter estimates, determined the conditions required to reduce extinction probability to some pre-defined acceptable threshold. Binomial regression models with mean population growth rate and the natural log of initial abundance were the best predictors of extinction probability 50 years into the future. For example, based on our regression models, an initial abundance of approximately 2400 females with an expected mean population growth rate of 1.0 will limit extinction risk for piping plovers in the Great Plains to less than 0.048. Our method provides a straightforward way of developing specific and measurable recovery criteria linked directly to the core issue of extinction risk. Published by Elsevier Ltd.

  17. Clinical Criteria for Physician Aid in Dying.

    Science.gov (United States)

    Orentlicher, David; Pope, Thaddeus Mason; Rich, Ben A

    2016-03-01

    More than 20 years ago, even before voters in Oregon had enacted the first aid in dying (AID) statute in the United States, Timothy Quill and colleagues proposed clinical criteria AID. Their proposal was carefully considered and temperate, but there were little data on the practice of AID at the time. (With AID, a physician writes a prescription for life-ending medication for a terminally ill, mentally capacitated adult.) With the passage of time, a substantial body of data on AID has developed from the states of Oregon and Washington. For more than 17 years, physicians in Oregon have been authorized to provide a prescription for AID. Accordingly, we have updated the clinical criteria of Quill, et al., based on the many years of experience with AID. With more jurisdictions authorizing AID, it is critical that physicians can turn to reliable clinical criteria. As with any medical practice, AID must be provided in a safe and effective manner. Physicians need to know (1) how to respond to a patient's inquiry about AID, (2) how to assess patient decision making capacity, and (3) how to address a range of other issues that may arise. To ensure that physicians have the guidance they need, Compassion & Choices convened the Physician Aid-in-Dying Clinical Criteria Committee, in July 2012, to create clinical criteria for physicians who are willing to provide AID to patients who request it. The committee includes experts in medicine, law, bioethics, hospice, nursing, social work, and pharmacy. Using an iterative consensus process, the Committee drafted the criteria over a one-year period.

  18. PCOS according to the Rotterdam consensus criteria : change in prevalence among WHO-II anovulation and association with metabolic factors

    NARCIS (Netherlands)

    Broekmans, F. J.; Knauff, E. A. H.; Valkenburg, O.; Laven, J. S.; Eijkemans, M. J.; Fauser, B. C. J. M.

    2006-01-01

    Objective The current report aims to compare the prevalence of polycystic ovary syndrome (PCOS) diagnosed according to the new Rotterdam criteria (Rott-PCOS) versus the previous criteria as formulated by the National Institutes of Health (NIH) (NIH-PCOS) in women with normogonadotropic (WHO-II) anov

  19. Nevada Test Site Waste Acceptance Criteria

    Energy Technology Data Exchange (ETDEWEB)

    U. S. Department of Energy, National Nuclear Security Administration Nevada Site Office

    2005-10-01

    This document establishes the U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Site Office (NNSA/NSO) waste acceptance criteria (WAC). The WAC provides the requirements, terms, and conditions under which the Nevada Test Site (NTS) will accept low-level radioactive (LLW) and mixed waste (MW) for disposal. It includes requirements for the generator waste certification program, characterization, traceability, waste form, packaging, and transfer. The criteria apply to radioactive waste received at the NTS Area 3 and Area 5 Radioactive Waste Management Complex (RWMC) for storage or disposal.

  20. NEVADA TEST SITE WASTE ACCEPTANCE CRITERIA

    Energy Technology Data Exchange (ETDEWEB)

    U.S. DEPARTMENT OF ENERGY, NATIONAL NUCLEAR SECURITY ADMINISTRATION, NEVADA SITE OFFICE

    2005-07-01

    This document establishes the U. S. Department of Energy, National Nuclear Security Administration Nevada Site Office (NNSA/NSO) waste acceptance criteria (WAC). The WAC provides the requirements, terms, and conditions under which the Nevada Test Site will accept low-level radioactive and mixed waste for disposal. Mixed waste generated within the State of Nevada by NNSA/NSO activities is accepted for disposal. It includes requirements for the generator waste certification program, characterization, traceability, waste form, packaging, and transfer. The criteria apply to radioactive waste received at the Nevada Test Site Area 3 and Area 5 Radioactive Waste Management Site for storage or disposal.

  1. On the origin of Hill's causal criteria.

    Science.gov (United States)

    Morabia, A

    1991-09-01

    The rules to assess causation formulated by the eighteenth century Scottish philosopher David Hume are compared to Sir Austin Bradford Hill's causal criteria. The strength of the analogy between Hume's rules and Hill's causal criteria suggests that, irrespective of whether Hume's work was known to Hill or Hill's predecessors, Hume's thinking expresses a point of view still widely shared by contemporary epidemiologists. The lack of systematic experimental proof to causal inferences in epidemiology may explain the analogy of Hume's and Hill's, as opposed to Popper's, logic.

  2. NEVADA TEST SITE WASTE ACCEPTANCE CRITERIA

    Energy Technology Data Exchange (ETDEWEB)

    U.S. DEPARTMENT OF ENERGY, NATIONAL NUCLEAR SECURITY ADMINISTRATION, NEVADA SITE OFFICE

    2005-07-01

    This document establishes the U. S. Department of Energy, National Nuclear Security Administration Nevada Site Office (NNSA/NSO) waste acceptance criteria (WAC). The WAC provides the requirements, terms, and conditions under which the Nevada Test Site will accept low-level radioactive and mixed waste for disposal. Mixed waste generated within the State of Nevada by NNSA/NSO activities is accepted for disposal. It includes requirements for the generator waste certification program, characterization, traceability, waste form, packaging, and transfer. The criteria apply to radioactive waste received at the Nevada Test Site Area 3 and Area 5 Radioactive Waste Management Site for storage or disposal.

  3. Nevada Test Site Waste Acceptance Criteria

    Energy Technology Data Exchange (ETDEWEB)

    U. S. Department of Energy, National Nuclear Security Administration Nevada Site Office

    2005-10-01

    This document establishes the U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Site Office (NNSA/NSO) waste acceptance criteria (WAC). The WAC provides the requirements, terms, and conditions under which the Nevada Test Site (NTS) will accept low-level radioactive (LLW) and mixed waste (MW) for disposal. It includes requirements for the generator waste certification program, characterization, traceability, waste form, packaging, and transfer. The criteria apply to radioactive waste received at the NTS Area 3 and Area 5 Radioactive Waste Management Complex (RWMC) for storage or disposal.

  4. Hanford Site Solid Waste Acceptance Criteria

    Energy Technology Data Exchange (ETDEWEB)

    1993-11-17

    This manual defines the Hanford Site radioactive, hazardous, and sanitary solid waste acceptance criteria. Criteria in the manual represent a guide for meeting state and federal regulations; DOE Orders; Hanford Site requirements; and other rules, regulations, guidelines, and standards as they apply to acceptance of radioactive and hazardous solid waste at the Hanford Site. It is not the intent of this manual to be all inclusive of the regulations; rather, it is intended that the manual provide the waste generator with only the requirements that waste must meet in order to be accepted at Hanford Site TSD facilities.

  5. A Study on Criteria for Barrel Lifetime

    Institute of Scientific and Technical Information of China (English)

    马吉胜; 郑坚; 邓辉咏

    2012-01-01

    Several criteria for barrel lifetime were summarized and discussed. Based on large amount of test data, the ad- vantages and disadvantages of the criteria were analyzed and the requirements for the easy and practical criterion were put forward. Then, a new criterion based on the radical wear at the start points of the barrel lands was proposed. The close in- terrelationship between the radical wear and interior ballistic characteristics was illuminated theoretically and experimental- ly. The research results show the great value of this criterion to solve the problem of barrel lifetime.

  6. Packaging design criteria for the MCO cask

    Energy Technology Data Exchange (ETDEWEB)

    Edwards, W.S.

    1997-01-30

    Approximately 2,100 metric tons of unprocessed, irradiated nuclear fuel elements are presently stored in the K Basins. To permit cleanup of the K Basins and fuel conditioning, the fuel will be transported from the K Basins to a Canister Storage Building in the 200 East Area. The purpose of this packaging design criteria is to provide criteria for the design, fabrication, and use of a packaging system to transport the large quantities of irradiated nuclear fuel elements positioned within Multiple Canister Overpacks.

  7. Packaging design criteria for the MCO cask

    Energy Technology Data Exchange (ETDEWEB)

    Clements, M.D.

    1996-01-01

    Approximately 2,100 metric tons of unprocessed, irradiated nuclear fuel elements are presently stored in the K Basins. To permit cleanup of the K Basins and fuel conditioning, the fuel will be transported from the K Basins to a Canister Storage Building in the 200 East Area. The purpose of this packaging design criteria is to provide criteria for the design, fabrication, and use of a packaging system to transport the large quantities of irradiated nuclear fuel elements positioned within Multiple Canister Overpacks.

  8. Packaging design criteria for the MCO cask

    Energy Technology Data Exchange (ETDEWEB)

    Edwards, W.S.

    1996-09-11

    Approximately 2,100 metric tons of unprocessed, irradiated nuclear fuel elements are presently stored in the K Basins. To permit cleanup of the K Basins and fuel conditioning, the fuel will be transported from the K Basins to a Canister Storage Building in the 200 East Area. The purpose of this packaging design criteria is to provide criteria for the design,fabrication, and use of a packaging system to transport the large quantities of irradiated nuclear fuel elements positioned within Multiple Canister Overpacks.

  9. Hanford Site Solid Waste Acceptance Criteria

    Energy Technology Data Exchange (ETDEWEB)

    1993-11-17

    This manual defines the Hanford Site radioactive, hazardous, and sanitary solid waste acceptance criteria. Criteria in the manual represent a guide for meeting state and federal regulations; DOE Orders; Hanford Site requirements; and other rules, regulations, guidelines, and standards as they apply to acceptance of radioactive and hazardous solid waste at the Hanford Site. It is not the intent of this manual to be all inclusive of the regulations; rather, it is intended that the manual provide the waste generator with only the requirements that waste must meet in order to be accepted at Hanford Site TSD facilities.

  10. DCD lung donation : donor criteria, procedural criteria, pulmonary graft function validation, and preservation

    NARCIS (Netherlands)

    Erasmus, Michiel E.; van Raemdonck, Dirk; Akhtar, Mohammed Zeeshan; Neyrinck, Arne; de Antonio, David Gomez; Varela, Andreas; Dark, John

    2016-01-01

    In an era where there is a shortage of lungs for transplantation is increased utilization of lungs from donation after circulatory death (DCD) donors. We review the reports of 11 controlled and 1 uncontrolled DCD programs focusing on donor criteria, procedural criteria, graft assessment, and preserv

  11. Defining criteria related to wastes for use in multi-criteria decision tool for nuclear accidents

    Energy Technology Data Exchange (ETDEWEB)

    Silva, Diogo N.G.; Guimaraes, Jean R.D., E-mail: dneves@biof.ufrj.br, E-mail: jeanrdg@biof.ufrj.br [Universidade Federal do Rio de Janeiro (UFRJ), RJ (Brazil). Instituto de Biofisica Carlos Chagas Filho; Rochedo, Elaine R.R.; De Luca, Christiano, E-mail: elainerochedo@gmail.com, E-mail: christiano_luca@hotmail.com [Instituto Militar de Engenharia (IME), Rio de Janeiro, RJ (Brazil). Programa de Engenharia Nuclear; Rochedo, Pedro R.R., E-mail: rochedopedro@gmail.com [Universidade Federal do Rio de Janeiro (UFRJ), RJ (Brazil). Instituto Alberto Luiz Coimbra de Pos-Graduacao e Pesquisa de Engenharia

    2013-07-01

    The selection of protective measures and strategies for remediation of contaminated areas after a nuclear accident must be based on previously established criteria in order to prevent stress of the population and the unnecessary exposure of workers. After a nuclear accident resulting in environmental contamination, decisions on remediation of areas is complex due to the large numbers of factors involved in decontamination processes. This work is part of a project which aims to develop a multi-criteria tool to support a decision-making process in cases of a radiological or a nuclear accident in Brazil. First, a database of remediation strategies for contaminated areas was created. In this process, the most relevant aspects for the implementation of these strategies were considered, including technical criteria regarding aspects related to the generation of wastes in a reference urban area, which are discussed in this paper. The specific objective of this study is to define criteria for the aspects of radioactive wastes, resulted by the implementation of some urban measures, in order to be incorporated in a multi-criteria decision tool. Main aspects considered were the type, the amount and the type of treatment necessary for each procedure. The decontamination procedures are then classified according to the selected criteria in order to feed the multi-criteria decision tool. This paper describes the steps for the establishment of these criteria and evaluates the potential for future applications in order to improve predictions and to support the decisions to be made. (author)

  12. The Rotterdam criteria for polycystic ovary syndrome: evidence-based criteria?

    Science.gov (United States)

    Wang, Rui; Mol, Ben Willem J

    2017-02-01

    The Rotterdam criteria for polycystic ovary syndrome (PCOS) are used by a wide range of medical professionals and researchers. However, the development of these criteria was based on expert meetings and not on evidence-based treatment guidance. Over the last decade, the Rotterdam criteria have been useful in guiding research, and a number of clinical studies on PCOS have been published consequently. We plead to revisit the Rotterdam criteria based on the available evidence in prognostic studies and randomized controlled trials. In this opinion paper, we provide arguments of the strengths and limitations of the Rotterdam criteria in guiding treatment selections and predicting prognoses in women with infertility. While the Rotterdam criteria have shown their advantages in predicting reproductive prognosis, the next step is to evaluate whether they can guide treatment choices in infertility as well as other health aspects of the syndrome. Based on available data in clinical studies, we should be able to determine whether the Rotterdam criteria are evidence-based criteria.

  13. Arrhythmogenic right ventricular dysplasia/cardiomyopathy diagnostic task force criteria: impact of new task force criteria

    NARCIS (Netherlands)

    M.G.P.J. Cox; J.J. van der Smagt; M. Noorman; A.C. Wiesfeld; P.G.A. Volders; I.M. van Langen; D.E. Atsma; D. Dooijes; A.C. Houweling; P. Loh; L. Jordaens; Y. Arens; M.J. Cramer; P.A. Doevendans; J.P. van Tintelen; A.A.M. Wilde; R.N.W. Hauer

    2010-01-01

    BACKGROUND: Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy (ARVD/C) Diagnostic Task Force Criteria (TFC) proposed in 1994 are highly specific but lack sensitivity. A new international task force modified criteria to improve diagnostic yield. A comparison of diagnosis by 1994 TFC versus ne

  14. Derivation and Validation of Systemic Lupus International Collaborating Clinics Classification Criteria for Systemic Lupus Erythematosus

    Science.gov (United States)

    Petri, Michelle; Orbai, Ana-Maria; Alarcón, Graciela S.; Gordon, Caroline; Merrill, Joan T.; Fortin, Paul R.; Bruce, Ian N.; Isenberg, David; Wallace, Daniel J.; Nived, Ola; Sturfelt, Gunnar; Ramsey-Goldman, Rosalind; Bae, Sang-Cheol; Hanly, John G.; Sanchez-Guerrero, Jorge; Clarke, Ann; Aranow, Cynthia; Manzi, Susan; Urowitz, Murray; Gladman, Dafna; Kalunian, Kenneth; Costner, Melissa; Werth, Victoria P.; Zoma, Asad; Bernatsky, Sasha; Ruiz-Irastorza, Guillermo; Khamashta, Munther A.; Jacobsen, Soren; Buyon, Jill P.; Maddison, Peter; Dooley, Mary Anne; van Vollenhoven, Ronald F.; Ginzler, Ellen; Stoll, Thomas; Peschken, Christine; Jorizzo, Joseph L.; Callen, Jeffrey P.; Lim, S. Sam; Fessler, Barri J.; Inanc, Murat; Kamen, Diane L.; Rahman, Anisur; Steinsson, Kristjan; Franks, Andrew G.; Sigler, Lisa; Hameed, Suhail; Fang, Hong; Pham, Ngoc; Brey, Robin; Weisman, Michael H.; McGwin, Gerald; Magder, Laurence S.

    2012-01-01

    Objective The Systemic Lupus Collaborating Clinics (SLICC) revised and validated the American College of Rheumatology (ACR) SLE classification criteria in order to improve clinical relevance, meet stringent methodology requirements and incorporate new knowledge in SLE immunology. Methods The classification criteria were derived from a set of 702 expert-rated patient scenarios. Recursive partitioning was used to derive an initial rule that was simplified and refined based on SLICC physician consensus. SLICC validated the classification criteria in a new validation sample of 690 SLE patients and controls. Results Seventeen criteria were identified. The SLICC criteria for SLE classification requires: 1) Fulfillment of at least four criteria, with at least one clinical criterion AND one immunologic criterion OR 2) Lupus nephritis as the sole clinical criterion in the presence of ANA or anti-dsDNA antibodies. In the derivation set, the SLICC classification criteria resulted in fewer misclassifications than the current ACR classification criteria (49 versus 70, p=0.0082), had greater sensitivity (94% versus 86%, p<0.0001) and equal specificity (92% versus 93%, p=0.39). In the validation set, the SLICC Classification criteria resulted in fewer misclassifications (62 versus 74, p=0.24), had greater sensitivity (97% versus 83%, p<0.0001) but less specificity (84% versus 96%, p<0.0001). Conclusions The new SLICC classification criteria performed well on a large set of patient scenarios rated by experts. They require that at least one clinical criterion and one immunologic criterion be present for a classification of SLE. Biopsy confirmed nephritis compatible with lupus (in the presence of SLE autoantibodies) is sufficient for classification. PMID:22553077

  15. Analysis and performance of various classification criteria sets in a Colombian cohort of patients with spondyloarthritis.

    Science.gov (United States)

    Bautista-Molano, Wilson; Landewé, Robert B M; Londoño, John; Romero-Sanchez, Consuelo; Valle-Oñate, Rafael; van der Heijde, Désirée

    2016-07-01

    The objective of this study was to investigate the performance of classification criteria sets (Assessment of SpondyloArthritis international Society (ASAS), European Spondylarthropathy Study Group (ESSG), and Amor) for spondyloarthritis (SpA) in a clinical practice cohort in Colombia and provide insight into how rheumatologists follow the diagnostic path in patients suspected of SpA. Patients with a rheumatologist's diagnosis of SpA were retrospectively classified according to three criteria sets. Classification rate was defined as the proportion of patients fulfilling a particular criterion. Characteristics of patients fulfilling and not fulfilling each criterion were compared. The ASAS criteria classified 81 % of all patients (n = 581) as having either axial SpA (44 %) or peripheral SpA (37 %), whereas a lower proportion met ESSG criteria (74 %) and Amor criteria (53 %). There was a high degree of overlap among the different criteria, and 42 % of the patients met all three criteria. Patients fulfilling all three criteria sets were older (36 vs. 30 years), had more SpA features (3 vs. 1 features), and more frequently had a current or past history of back pain (77 vs. 43 %), inflammatory back pain (47 vs. 13 %), enthesitis (67 vs. 26 %), and buttock pain (37 vs. 13 %) vs. those not fulfilling any criteria. HLA-B27, radiographs, and MRI-SI were performed in 77, 59, and 24 % of the patients, respectively. The ASAS criteria classified more patients as having SpA in this Colombian cohort when the rheumatologist's diagnosis is used as an external standard. Although physicians do not perform HLA-B27 or imaging in all patients, they do require these tests if the clinical symptoms fall short of confirming SpA and suspicion remains.

  16. Task Force on Catastrophic Antiphospholipid Syndrome (APS) and Non-criteria APS Manifestations (II): thrombocytopenia and skin manifestations.

    Science.gov (United States)

    Cervera, R; Tektonidou, M G; Espinosa, G; Cabral, A R; González, E B; Erkan, D; Vadya, S; Adrogué, H E; Solomon, M; Zandman-Goddard, G; Shoenfeld, Y

    2011-02-01

    The objectives of the 'Task Force on Catastrophic Antiphospholipid Syndrome (APS) and Non-criteria APS Manifestations' were to assess the clinical utility of the international consensus statement on classification criteria and treatment guidelines for the catastrophic APS, to identify and grade the studies that analyze the relationship between the antiphospholipid antibodies and the non-criteria APS manifestations, and to present the current evidence regarding the accuracy of these non-criteria APS manifestations for the detection of patients with APS. This article summarizes the studies analyzed on thrombocytopenia and skin manifestations, and presents the recommendations elaborated by the Task Force after this analysis.

  17. Optimum control criteria for an electric driver for dynamic systems

    Directory of Open Access Journals (Sweden)

    Cecilia E. Sandoval Ruiz

    2010-04-01

    Full Text Available This work was aimed at optimising control parameters for variable speed control and post-tensioning torque by con-trolling the current of DC motors forming part of a dynamic system (in a paper-making production line by designing controllers based on absolute value and optimal symmetry criteria. A mathematical model representing an electric drive system for controlling DC motor speed and torque in a paper-rolling system was defined, a control algorithm adjusting the parameters was designed and an electric drive system simulated. The methodology consisted of a lite-rature search and a field study for defining the model and establishing the parameters to be simulated, thereby pre-senting an analytical and descriptive project. The results led to observing the efficiency of the controllers so designed and the overall drive system for which speed and current (power continue being the reference signal, leading to the conclusion that the criteria selected for control design were suitable and representing an input in developing applica-tions for monitoring dynamic electric drive systems.

  18. 24 CFR 214.103 - Approval criteria.

    Science.gov (United States)

    2010-04-01

    ... counseling staff must possess a working knowledge of HUD's housing and single-family mortgage insurance... COUNSELING PROGRAM Approval and Disapproval of Housing Counseling Agencies § 214.103 Approval criteria. The... counseling agencies, branches, and affiliates that are included in one application: (a) Nonprofit and...

  19. MDS research criteria for prodromal Parkinson's disease

    NARCIS (Netherlands)

    Berg, D; Postuma, R.B.; Adler, C.H.; Bloem, B.R.; Chan, P.; Dubois, B.; Gasser, T.; Goetz, C.G.; Halliday, G.; Joseph, L.; Lang, A.E.; Liepelt-Scarfone, I.; Litvan, I.; Marek, K.; Obeso, J.; Oertel, W.; Olanow, C.W.; Poewe, W.; Stern, M.; Deuschl, G.

    2015-01-01

    This article describes research criteria and probability methodology for the diagnosis of prodromal PD. Prodromal disease refers to the stage wherein early symptoms or signs of PD neurodegeneration are present, but classic clinical diagnosis based on fully evolved motor parkinsonism is not yet

  20. MDS research criteria for prodromal Parkinson's disease.

    Science.gov (United States)

    Berg, Daniela; Postuma, Ronald B; Adler, Charles H; Bloem, Bastiaan R; Chan, Piu; Dubois, Bruno; Gasser, Thomas; Goetz, Christopher G; Halliday, Glenda; Joseph, Lawrence; Lang, Anthony E; Liepelt-Scarfone, Inga; Litvan, Irene; Marek, Kenneth; Obeso, José; Oertel, Wolfgang; Olanow, C Warren; Poewe, Werner; Stern, Matthew; Deuschl, Günther

    2015-10-01

    This article describes research criteria and probability methodology for the diagnosis of prodromal PD. Prodromal disease refers to the stage wherein early symptoms or signs of PD neurodegeneration are present, but classic clinical diagnosis based on fully evolved motor parkinsonism is not yet possible. Given the lack of clear neuroprotective/disease-modifying therapy for prodromal PD, these criteria were developed for research purposes only. The criteria are based upon the likelihood of prodromal disease being present with probable prodromal PD defined as ≥80% certainty. Certainty estimates rely upon calculation of an individual's risk of having prodromal PD, using a Bayesian naïve classifier. In this methodology, a previous probability of prodromal disease is delineated based upon age. Then, the probability of prodromal PD is calculated by adding diagnostic information, expressed as likelihood ratios. This diagnostic information combines estimates of background risk (from environmental risk factors and genetic findings) and results of diagnostic marker testing. In order to be included, diagnostic markers had to have prospective evidence documenting ability to predict clinical PD. They include motor and nonmotor clinical symptoms, clinical signs, and ancillary diagnostic tests. These criteria represent a first step in the formal delineation of early stages of PD and will require constant updating as more information becomes available. © 2015 International Parkinson and Movement Disorder Society.

  1. Harmonized diagnostic criteria for Alzheimer's disease

    DEFF Research Database (Denmark)

    Morris, J C; Blennow, K; Froelich, L

    2014-01-01

    BACKGROUND: Two major sets of criteria for the clinical diagnosis of Alzheimer's disease (AD) recently have been published, one from an International Working Group (IWG) and the other from working groups convened by the National Institute on Aging (NIA) and the Alzheimer's Association (AA...

  2. Recent developemts in multiple criteria decision making

    Directory of Open Access Journals (Sweden)

    Z. Zionts

    2003-12-01

    Full Text Available Problems involving more than one criterion abound. To help in the solution of such problems, a field of management science and operations research known as multiple criteria decision making (MCDM has emerged to help solve such problems. In this paper we discuss some recent developments in this important field.

  3. CORAL REEF BIOLOGICAL CRITERIA: USING THE CLEAN ...

    Science.gov (United States)

    Coral reefs are declining at unprecedented rates worldwide due to multiple interactive stressors including climate change and land-based sources of pollution. The Clean Water Act (CWA) can be a powerful legal instrument for protecting water resources, including the biological inhabitants of coral reefs. The objective of the CWA is to restore and maintain the chemical, physical and biological integrity of water resources. Coral reef protection and restoration under the Clean Water Act begins with water quality standards - provisions of state or Federal law that consist of a designated use(s) for the waters of the United States and water quality criteria sufficient to protect the uses. Aquatic life use is the designated use that is measured by biological criteria (biocriteria). Biocriteria are expectations set by a jurisdiction for the quality and quantity of living aquatic resources in a defined waterbody. Biocriteria are an important addition to existing management tools for coral reef ecosystems. The Technical Support Document “Coral Reef Biological Criteria: Using the Clean Water Act to Protect a National Treasure” will provide a framework to aid States and Territories in their development, adoption, and implementation of coral reef biocriteria in their respective water quality standards. The Technical Support Document “Coral Reef Biological Criteria: Using the Clean Water Act to Protect a National Treasure” will provide a framework for coral re

  4. Nevada Test Site Waste Acceptance Criteria (NTSWAC)

    Energy Technology Data Exchange (ETDEWEB)

    NNSA/NSO Waste Management Project

    2008-06-01

    This document establishes the U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office, Nevada Test Site Waste Acceptance Criteria (NTSWAC). The NTSWAC provides the requirements, terms, and conditions under which the Nevada Test Site will accept low-level radioactive (LLW) and LLW Mixed Waste (MW) for disposal.

  5. MDS research criteria for prodromal Parkinson's disease

    NARCIS (Netherlands)

    Berg, D; Postuma, R.B.; Adler, C.H.; Bloem, B.R.; Chan, P.; Dubois, B.; Gasser, T.; Goetz, C.G.; Halliday, G.; Joseph, L.; Lang, A.E.; Liepelt-Scarfone, I.; Litvan, I.; Marek, K.; Obeso, J.; Oertel, W.; Olanow, C.W.; Poewe, W.; Stern, M.; Deuschl, G.

    2015-01-01

    This article describes research criteria and probability methodology for the diagnosis of prodromal PD. Prodromal disease refers to the stage wherein early symptoms or signs of PD neurodegeneration are present, but classic clinical diagnosis based on fully evolved motor parkinsonism is not yet possi

  6. [Primary childhood vasculitis new classification criteria

    DEFF Research Database (Denmark)

    Herlin, T.; Nielsen, Susan

    2008-01-01

    for the classification of childhood vasculitides have been proposed by a working group of the Pediatric Rheumatology European Society and the EULAR Standing Committee on Paediatric Rheumatology. This review describes primary vasculitides from a pediatric perspective referring to the new consensus criteria Udgivelsesdato...

  7. Product Variables as Criteria of Teacher Effectiveness.

    Science.gov (United States)

    Schofield, Hilary L.; Start, K. B.

    1979-01-01

    Explanations are offered for observed discrepant and null findings in the area of predictive information about teacher effectiveness. It is argued that if tautologies are to be avoided, only product variables are appropriate criteria of success. Some recommendations regarding future research are offered. (Author/GSK)

  8. Quantum teleportation criteria for continuous variables

    CERN Document Server

    Grangier, P; Grangier, Philippe; Grosshans, Frederic

    2000-01-01

    We discuss the criteria presently used for evaluating the efficiency of quantum teleportation schemes for continuous variables. It is argued that the fidelity criterion used so far has some severe drawbacks, and that a fidelity value larger than 2/3 is actually required for successful quantum teleportation. This value has never been reached experimentally so far.

  9. Criteria for the replacement of restorations

    DEFF Research Database (Denmark)

    Wilson, Nairn; Lynch, Christopher; Brunton, Paul Brunton

    2016-01-01

    The replacement of a restoration is one of the most common procedures in dentistry. However, the criteria for such intervention, excluding catastrophic failure and persistent discomfort and pain, continue to be the subject of considerable debate. The decision-making process remains subjective...

  10. 15 CFR 8b.13 - Employment criteria.

    Science.gov (United States)

    2010-01-01

    ... sensory, manual, or speaking skills, the test results accurately to reflect the applicant's or employee's....13 Commerce and Foreign Trade Office of the Secretary of Commerce PROHIBITION OF DISCRIMINATION... Practices § 8b.13 Employment criteria. (a) A recipient may not make use of any employment test or...

  11. 45 CFR 1151.33 - Employment criteria.

    Science.gov (United States)

    2010-10-01

    ... sensory, manual, or speaking skills, the test results accurately reflect the applicant's or employee's job... HUMANITIES NATIONAL ENDOWMENT FOR THE ARTS NONDISCRIMINATION ON THE BASIS OF HANDICAP Discrimination Prohibited Employment § 1151.33 Employment criteria. (a) A recipient may not make use of any employment...

  12. Criteria for the selection of ERP software

    Directory of Open Access Journals (Sweden)

    2007-01-01

    Full Text Available The implementation of an ERP software package is an important investment for an organization, which is characterized also by a high degree of risk. Selecting the most appropriate software is a necessary condition for a successful implementation. This paper is describing the major aspects of software selection in general and the relevant criteria in the case of ERP software.

  13. Sharper criteria for the wave collapse

    DEFF Research Database (Denmark)

    Kuznetsov, E.A.; Juul Rasmussen, J.; Rypdal, K.

    1995-01-01

    Sharper criteria for three-dimensional wave collapse described by the Nonlinear Schrodinger Equation (NLSE) are derived. The collapse threshold corresponds to the ground state soliton which is known to be unstable. Thus, for nonprefocusing distributions this represents the separatrix between...

  14. Eigenvalues of the -Laplacian and disconjugacy criteria

    Directory of Open Access Journals (Sweden)

    Pinasco Juan P

    2006-01-01

    Full Text Available We derive oscillation and nonoscillation criteria for the one-dimensional -Laplacian in terms of an eigenvalue inequality for a mixed problem. We generalize the results obtained in the linear case by Nehari and Willett, and the proof is based on a Picone-type identity.

  15. Performance Funding Criteria, Levels, and Methods.

    Science.gov (United States)

    Serban, Andreea M.

    1998-01-01

    Although selecting goals and indicators is the most challenging task of performance funding, implementation requires development of other critical elements: success criteria to measure institutional performance; indicator weights for percent of funding allocated to each indicator; an allocation method for setting the relationship between…

  16. European Analytical Criteria: Past, Present and Future

    NARCIS (Netherlands)

    Vanhaecke, L.; Gowik, P.; Bizec, Le B.; Ginkel, van L.A.; Bichon, E.; Blokland, M.H.; Brabander, de H.F.

    2011-01-01

    In this paper, the past, present, and (possible) future of the European analytical criteria for residues are described. The elaboration of the revision of Commission Decision 93/256/EC was a long process starting in 1996 and ending with the formation of a European Commission (EC) working group in 19

  17. Manpower Planning Criteria Manual, Construction Grants Section.

    Science.gov (United States)

    Texas State Dept. of Water Resources, Austin.

    This document presents the material developed in conjunction with a project directed to test a methodology that a state water pollution control agency can use in determining its manpower and training needs. Included is a compilation of the manpower planning criteria used to relate numbers and types of personnel with deferred workloads. It also…

  18. Manpower Planning Criteria Manual, Construction Grants Section.

    Science.gov (United States)

    Texas State Dept. of Water Resources, Austin.

    This document presents the material developed in conjunction with a project directed to test a methodology that a state water pollution control agency can use in determining its manpower and training needs. Included is a compilation of the manpower planning criteria used to relate numbers and types of personnel with deferred workloads. It also…

  19. Criteria and suspension levels in diagnostic radiology.

    Science.gov (United States)

    Malone, J; Baldelli, P; Balter, S; Bischof, N; Bosmans, H; Dowling, A; Edyvean, S; Gallagher, A; Faulkner, K; Horner, K; Malone, L; Mclean, I D; O'Connor, U; Schreiner, A; Vassileva, J; Vano, E; Zoetelief, J

    2013-02-01

    The EC (European Council) Directive on radiation protection of patients requires that criteria for acceptability of equipment in diagnostic radiology, nuclear medicine and radiotherapy be established throughout the member states. This study reviews the background to this requirement and to its implementation in practice. It notes and considers parallel requirements in the EC medical devices directive and International Electrotechnical Commission standards that it is also important to consider and that both sets of requirements should ideally be harmonised due to the global nature of the equipment industry. The study further reviews the types of criteria that can be well applied for the above purposes, and defines qualitative criteria and suspension levels suitable for application. Both are defined and relationships with other acceptance processes are considered (including acceptance testing at the time of purchase, commissioning and the issue of second-hand equipment). Suspension levels are divided into four types, A, B, C and D, depending on the quality of evidence and consensus they are based on. Exceptional situations involving, for example, new or rapidly evolving technology are also considered. The publication and paper focuses on the role of the holder of the equipment and related staff, particularly the medical physics expert and the practitioner. Advice on how the criteria should be created and implemented is provided for these groups and how this might be coordinated with the supplier. Additional advice on the role of the regulator is provided.

  20. 13 CFR 113.505 - Employment criteria.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Employment criteria. 113.505 Section 113.505 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION NONDISCRIMINATION IN...) Use of such test or other criterion is shown to predict validly successful performance in the...

  1. 14 CFR 1253.505 - Employment criteria.

    Science.gov (United States)

    2010-01-01

    ... OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Employment in Education Programs or Activities Prohibited § 1253.505 Employment... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Employment criteria. 1253.505 Section...

  2. 7 CFR 15a.52 - Employment criteria.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Employment criteria. 15a.52 Section 15a.52 Agriculture Office of the Secretary of Agriculture EDUCATION PROGRAMS OR ACTIVITIES RECEIVING OR BENEFITTING FROM FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Employment in Education Programs...

  3. 40 CFR 5.505 - Employment criteria.

    Science.gov (United States)

    2010-07-01

    ... OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Employment in Education Programs or Activities Prohibited § 5.505 Employment... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Employment criteria. 5.505 Section...

  4. European Analytical Criteria: Past, Present and Future

    NARCIS (Netherlands)

    Vanhaecke, L.; Gowik, P.; Bizec, Le B.; Ginkel, van L.A.; Bichon, E.; Blokland, M.H.; Brabander, de H.F.

    2011-01-01

    In this paper, the past, present, and (possible) future of the European analytical criteria for residues are described. The elaboration of the revision of Commission Decision 93/256/EC was a long process starting in 1996 and ending with the formation of a European Commission (EC) working group in

  5. Regularized multiple criteria linear programs for classification

    Institute of Scientific and Technical Information of China (English)

    SHI Yong; TIAN YingJie; CHEN XiaoJun; ZHANG Peng

    2009-01-01

    Although multiple criteria mathematical program (MCMP), as an alternative method of classification, has been used in various real-life data mining problems, its mathematical structure of solvability is still challengeable. This paper proposes a regularized multiple criteria linear program (RMCLP) for two classes of classification problems. It first adds some regularization terms in the objective function of the known multiple criteria linear program (MCLP) model for possible existence of solution. Then the paper describes the mathematical framework of the solvability. Finally, a series of experimental tests are conducted to illustrate the performance of the proposed RMCLP with the existing methods: MCLP, multiple criteria quadratic program (MCQP), and support vector machine (SVM). The results of four publicly available datasets and a real-life credit dataset all show that RMCLP is a competitive method in classification. Furthermore, this paper explores an ordinal RMCLP (ORMCLP) model for ordinal multi-group problems. Comparing ORMCLP with traditional methods such as One-Against-One, One-Against-The rest on large-scale credit card dataset, experimental results show that both ORMCLP and RMCLP perform well.

  6. Efficient Diversification According to Stochastic Dominance Criteria

    NARCIS (Netherlands)

    Kuosmanen, T.K.

    2004-01-01

    This paper develops the first operational tests of portfolio efficiency based on the general stochastic dominance (SD) criteria that account for an infinite set of diversification strategies. The main insight is to preserve the cross-sectional dependence of asset returns when forming portfolios by

  7. Nevada Test Site Waste Acceptance Criteria (NTSWAC)

    Energy Technology Data Exchange (ETDEWEB)

    NNSA/NSO Waste Management Project

    2008-06-01

    This document establishes the U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office, Nevada Test Site Waste Acceptance Criteria (NTSWAC). The NTSWAC provides the requirements, terms, and conditions under which the Nevada Test Site will accept low-level radioactive (LLW) and LLW Mixed Waste (MW) for disposal.

  8. Brain Death,Concept and Criteria

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    The concept of brain death originated in France. In 1959, the French scholars P. Mollaret and M. Goulon proposed the concept of "coma de- passe" or "brain death" for the first time and reported 23 cases with such symptoms. The first guidelines (the Harvard criteria) for diagnosing brain death was established in 1968, defining brain death

  9. Performance of Information Criteria for Spatial Models.

    Science.gov (United States)

    Lee, Hyeyoung; Ghosh, Sujit K

    2009-01-01

    Model choice is one of the most crucial aspect in any statistical data analysis. It is well known that most models are just an approximation to the true data generating process but among such model approximations it is our goal to select the "best" one. Researchers typically consider a finite number of plausible models in statistical applications and the related statistical inference depends on the chosen model. Hence model comparison is required to identify the "best" model among several such candidate models. This article considers the problem of model selection for spatial data. The issue of model selection for spatial models has been addressed in the literature by the use of traditional information criteria based methods, even though such criteria have been developed based on the assumption of independent observations. We evaluate the performance of some of the popular model selection critera via Monte Carlo simulation experiments using small to moderate samples. In particular, we compare the performance of some of the most popular information criteria such as Akaike Information Criterion (AIC), Bayesian Information Criterion (BIC), and Corrected AIC (AICc) in selecting the true model. The ability of these criteria to select the correct model is evaluated under several scenarios. This comparison is made using various spatial covariance models ranging from stationary isotropic to nonstationary models.

  10. 45 CFR 605.13 - Employment criteria.

    Science.gov (United States)

    2010-10-01

    ... speaking skills, the test results accurately reflect the applicant's or employee's job skills, aptitude, or... job-related for the position in question, and (2) alternative job-related tests or criteria that do... impaired sensory, manual, or speaking skills (except where those skills are the factors that the...

  11. 43 CFR 17.212 - Employment criteria.

    Science.gov (United States)

    2010-10-01

    ..., manual, or speaking skills the test results accurately reflect the applicant's or employee's job skills... shown to be job-related for the position in question, and (2) alternative job-related tests or criteria... employee's impaired sensory, manual, or speaking skills (except where those skills are the factors that...

  12. Construction of plateaued functions satisfying multiple criteria

    Institute of Scientific and Technical Information of China (English)

    Zhang Weiguo

    2005-01-01

    A class of plateaued functions has been got by using the Maiorana-McFarland construction. A variety of desirable criteria for functions with cryptographic application could be satisfied: balancedness, high nonlinearity, correlation immunity of reasonably high order, strict avalanche criterion, non-existence of non-zero linear structures, good global avalanche characteristics, etc.

  13. Identifying transudates misclassified by Light's criteria.

    Science.gov (United States)

    Porcel, José M

    2013-07-01

    Light's criteria combine three dichotomous tests into a decision rule that is considered positive if any one of the tests is positive. This strategy clearly maximizes sensitivity, although at the expense of specificity. Although Light's criteria identify 98% of pleural exudates, they misclassify about 25% of transudates as exudates. The way to overcome this limitation is discussed in this review. Traditionally, measurement of the protein gradient between the serum and pleural fluid has been recommended to decrease the misclassification rate of Light's criteria. A recent study demonstrated that a gradient between the albumin levels in the serum and the pleural fluid more than 1.2 g/dl performs significantly better than a protein gradient more than 3.1 g/dl to correctly categorize mislabeled cardiac effusions (83 vs. 55%). On the other hand, the accuracy of a pleural fluid to serum albumin ratio less than 0.6 excelled when compared with albumin and protein gradients in patients with miscategorized hepatic hydrothoraces (77 vs. 62 vs. 61%). The simplest strategy to reveal the true transudative nature of heart failure-related effusions, labeled as exudates by Light's criteria, is to calculate the serum to pleural fluid albumin gradient. Conversely, for misclassified hepatic hydrothoraces, measurement of the pleural to serum albumin ratio is recommended. The serum to pleural fluid protein gradient should no longer be considered the preferred test for this purpose.

  14. 24 CFR 8.12 - Employment criteria.

    Science.gov (United States)

    2010-04-01

    ... applicant's or employee's job skills, aptitude, or whatever other factor the test purports to measure... URBAN DEVELOPMENT Employment § 8.12 Employment criteria. (a) A recipient may not use any employment test... any class of individuals with handicaps unless: (1) The recipient demonstrates that the test score...

  15. 45 CFR 84.13 - Employment criteria.

    Science.gov (United States)

    2010-10-01

    ..., the test results accurately reflect the applicant's or employee's job skills, aptitude, or whatever... Employment criteria. (a) A recipient may not make use of any employment test or other selection criterion...: (1) The test score or other selection criterion, as used by the recipient, is shown to be...

  16. 22 CFR 217.13 - Employment criteria.

    Science.gov (United States)

    2010-04-01

    ..., the test results accurately reflect the applicant's or employee's job skills, aptitude, or whatever... criteria. (a) A recipient may not make use of any employment test or other selection criterion that screens... test score or other selection criterion, as used by the recipient, is shown to be job-related for...

  17. 22 CFR 142.13 - Employment criteria.

    Science.gov (United States)

    2010-04-01

    ... results accurately reflect the applicant's or employee's job skills, aptitude, or whatever factor the test... criteria. (a) A recipient may not make use of any employment test or other selection criterion that screens... test score or other selection criterion, as used by the recipient, is shown to be job-related for...

  18. 10 CFR 1040.68 - Employment criteria.

    Science.gov (United States)

    2010-01-01

    ..., the test results accurately reflect the applicant's or employee's job skills, aptitude or other... Practices § 1040.68 Employment criteria. (a) A recipient may not use any employment test or other selection criterion that screens out or tends to screen out handicapped persons unless the test score or...

  19. 38 CFR 18.413 - Employment criteria.

    Science.gov (United States)

    2010-07-01

    ... accurately reflect the applicant's or employee's job skills, aptitude, or whatever other factor the test... Employment criteria. (a) A recipient may not use any employment test or other selection criterion that... test score or other selection criterion, as used by the recipient, is shown to be job-related for...

  20. Evidence on changes in aid allocation criteria

    NARCIS (Netherlands)

    Claessens, S.; Cassimon, D.; Van Campenhout, B.

    2009-01-01

    Have donors changed their aid-allocation criteria over the past three decades toward greater selectivity, a frequently stated goal of the international development community? Using data on how 22 donors allocated their bilateral aid among 147 countries over 1970-2004, the article finds that after th

  1. Borders and Legal Criteria for Acquiring Nationality

    Directory of Open Access Journals (Sweden)

    María Elósegui Itxaso

    2008-09-01

    Full Text Available Legal criteria for acquiring nationality are crucial in the integration of persons into society, since they provide access to the right to vote. Until now, the criteria most frequently used are those of ius soli (birth and ius sanguinis (nationality is inherited from the parents, which comply with previous anthropological approaches and which jurists accept without reflection, or consider to be unshakeable traditions.The author’s proposal in this article is to accept that some of these legal criteria should be reformed, though not in an anarchic manner. On one hand, some of the ethnic criteria may be respected, but on the other, the processes of acquiring nationality should be streamlined by accepting the desire of persons wanting to change their nationality on moving to a new country of residence. Meanwhile, we must establish channels of demand for accepting the democratic values and legal system of the welcoming country, as a result of which it would be fair to call for a prior learning period before the rights to nationality and suffrage are granted. The author also adds – and accepts as being a fundamental element – some of Habermas’ inclusion theses, though she stresses that this discourse should be organised into two specific, feasible legal solutions or rather, in a realistic manner.

  2. 16 CFR 1031.14 - Observation criteria.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Observation criteria. 1031.14 Section 1031... COMMISSION EMPLOYEE INVOLVEMENT IN VOLUNTARY STANDARDS ACTIVITIES Employee Involvement § 1031.14 Observation... sole purpose of observation, with the advance approval of his or her supervisor and any other person...

  3. Education Criteria for Performance Excellence, 2003.

    Science.gov (United States)

    American Society for Quality, Milwaukee, WI.

    The criteria described in this document are the basis for organizational self-assessments, for making awards, and for giving feedback to applicants. They are built upon the following values and concepts: visionary leadership; learning-centered education; organizational and personal learning; valuing faculty, staff, and partners; agility; focus on…

  4. Modified PIOPED criteria used in clinical practice.

    Science.gov (United States)

    Freitas, J E; Sarosi, M G; Nagle, C C; Yeomans, M E; Freitas, A E; Juni, J E

    1995-09-01

    To assess the use of modified PIOPED scintigraphic criteria for lung scan (V/Q) interpretation to detect pulmonary embolism (PE), we prospectively applied these criteria in suspected PE patients referred for V/Q from 9/1/92 to 2/7/94. PIOPED criteria were modified by placing a moderate segmental perfusion mismatch in the intermediate instead of low probability of PE category and using the "stripe sign." Patients were studied by six-view V/Q imaging using 74 MBq (2 mCi) 99mTc-MAA followed by 148-370 MBq (4-10 mCi) 99mTc-DTPA aerosol, contrast pulmonary selective angiography and Doppler sonography with leg compression as needed. Patients underwent follow-up (mean 13.9 mo) to detect subsequent thromboembolic events. In this study group, 1000 patients were studied by V/Q followed by angiography in 133 patients. The distribution of V/Q-assigned PE probabilities was: high probability 5.7%, intermediate 17.4%, low 41.4% and normal 35.5%. Group A patients (133) underwent angiography, which resulted in the determination of a 27.1% PE prevalence. Group B patients (867) did not have angiograms; the clinical prevalence of PE was 7.5%. In the total study population, the positive predictive value of a high probability V/Q study for PE (10.1% prevalence) was 98.2%, intermediate probability V/Q study for PE was 24.1% and a low probability study for PE was only 0.5%. Modified PIOPED V/Q interpretation criteria afford better angioproven PE discrimination between intermediate (31.8% PE prevalence) and low (5.5% PE prevalence) probability V/Q results than reported for PIOPED intermediate (32.6% PE prevalence) and low (16.3% PE prevalence) probability V/Q interpretation criteria.

  5. Dermatology position paper on the revision of the 1982 ACR criteria for systemic lupus erythematosus.

    Science.gov (United States)

    Albrecht, J; Berlin, J A; Braverman, I M; Callen, J P; Connolly, M K; Costner, M I; Dutz, J; Fivenson, D; Franks, A G; Jorizzo, J L; Lee, L A; McCauliffe, D P; Sontheimer, R D; Werth, V P

    2004-01-01

    The 1982 ACR classification criteria have become de facto diagnostic criteria for systemic lupus erythematosus (SLE), but a review of the criteria is necessary to include recent diagnostic tests. The criteria were not developed with the help of dermatologists, and assign too much weight to the skin as one expression of a multiorgan disease. Consequently, patients with skin diseases are classified as SLE based mostly on skin symptoms. We discuss specific problems with each dermatologic criterion, but changes must await a new study. We suggest the following guidelines for such a study, aimed at revision of the criteria. 1) The SLE patient group should be recruited in part by dermatologists. 2) The study should evaluate an appropriate international ethnic/racial mix, including late onset SLE as well as pediatric patients. 3) All patients should have current laboratory and clinical evaluations, as suggested in the paper, to assure the criteria can be up-to-date. This includes anti-SS-A and anti-SS-B antibodies and skin biopsies for suspected cutaneous lupus erythematosus except for nonscarring alopecia and oral ulcers. 4) The study should be based on a series of transparent power calculations. 5) The control groups should represent relevant differential diagnoses in numbers large enough to assess diagnostic problems that might be specific to these differential diagnoses. In order to demonstrate specificity of the criteria with a 95% confidence interval between 90 and 100%, each control group of the above should have at least 73 patients.

  6. Development and validation of sustainability criteria of administrative green schools in Iran.

    Science.gov (United States)

    Meiboudi, Hossein; Lahijanian, Akramolmolok; Shobeiri, Seyed Mohammad; Jozi, Seyed Ali; Azizinezhad, Reza

    2017-07-15

    Environmental responsibility in school has led to the emergence of a variety of criteria to administer green schools' contributions to sustainability. Sustainability criteria of administrative green schools need validity, reliability and norms. The aim of the current study was to develop and validate assessment criteria for green schools in Iran based on the role of academia. A national survey was conducted to obtain data on sustainability criteria initiatives for green schools and the Iranian profile was defined. An initial pool of 71 items was generated and after its first edition, 63 items were selected to comprise the sustainability criteria. Engineering-architectural and behavioral aspects of this sustainability criteria were evaluated through a sample of 1218 graduate students with environmental degrees from Iran's universities. Exploratory factor analysis using principal components and promax rotation method showed that these 9 criteria have simple structures and are consistent with the theoretical framework. The reliability coefficients of subscales ranged between 0.62 (participation) and 0.84 (building location and position). The study's survey of correlation coefficients between items and subscales illustrated that those coefficients varied between 0.24 and 0.68. Copyright © 2017 Elsevier Ltd. All rights reserved.

  7. The clinical features of mania and their representation in modern diagnostic criteria.

    Science.gov (United States)

    Kendler, K S

    2017-04-01

    This review seeks to determine the degree to which modern operationalized diagnostic criteria for mania reflect the clinical features of mania described historically by expert textbook authors. Clinical descriptions of mania appearing in 18 textbooks published between 1899 and 1956 were reviewed and compared to the criteria for mania from six modern operationalized diagnostic systems. Twenty-two prominent symptoms and signs were reported by five or more authors. Two symptoms (elevated mood and grandiosity) and four signs (hyperactivity, pressured speech, irritability, and new activities with painful consequences) were reported by every author. A strong relationship was seen between the frequency with which the clinical features were reported and the likelihood of their inclusion in modern diagnostic systems. However, many symptoms and signs including impulsivity, hypersexuality, mood lability, altered moral standards, increased humor, hypergraphia, and a vigorous physical appearance were not included in any modern criteria. Indeed, DSM-5 contains only eight of the historically noted clinical features. We conclude that modern operationalized criteria for mania well reflect symptoms and signs frequently reported by historical experts. This suggests that the clinical construct of mania has been relatively stable in western Psychiatry since the turn of the 20th century. However, many useful clinical features of mania described in these textbooks are missing from these criteria thereby illustrating the limitations of clinical evaluations restricted to the assessment of only current diagnostic criteria. The disorders we study and treat are considerably richer clinically than is reflected in the DSM criteria which we use to diagnose them.

  8. The leak before break criteria, requirements and implications; El criterio de fuga antes de ruptura, requerimientos e implicaciones

    Energy Technology Data Exchange (ETDEWEB)

    Martinez M, E

    1992-05-15

    Inside this work a general balance is made on the Leak before break approach (LBB), like they are the history and licensing, those limitations, the acceptance criteria of the LBB, the current state of the regulatory development and the current state of it application in countries like E.U.A, Germany, Canada, Italy and France. Everything it with the purpose of evaluating the opportunities that offers the LBB criteria for it possible application in Mexico. (Author)

  9. Intermittent explosive disorder: development of integrated research criteria for Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition.

    Science.gov (United States)

    Coccaro, Emil F

    2011-01-01

    This study was designed to develop a revised diagnostic criteria set for intermittent explosive disorder (IED) for consideration for inclusion in Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-V). This revised criteria set was developed by integrating previous research criteria with elements from the current DSM-IV set of diagnostic criteria. Evidence supporting the reliability and validity of IED-IR ("IED Integrated Criteria") in a new and well-characterized group of subjects with personality disorder is presented. Clinical, phenomenologic, and diagnostic data from 201 individuals with personality disorder were reviewed. All IED diagnoses were assigned using a best-estimate process (eg, kappa for IED-IR >0.85). In addition, subjects meeting IED-IR criteria had higher scores on dimensional measures of aggression and had lower global functioning scores than non-IED-IR subjects, even when related variables were controlled. The IED-IR criteria were more sensitive than the DSM-IV criteria only in identifying subjects with significant impulsive-aggressive behavior by a factor of 16. We conclude that the IED-IR criteria can be reliably applied and have sufficient validity to warrant consideration as DSM-V criteria for IED.

  10. Recognizing systemic sclerosis: comparative analysis of various sets of classification criteria.

    Science.gov (United States)

    Romanowska-Próchnicka, Katarzyna; Walczyk, Marcela; Olesińska, Marzena

    2016-01-01

    Systemic sclerosis is a complex disease characterized by autoimmunity, vasculopathy and tissue fibrosis. Although most patients present with some degree of skin sclerosis, which is a distinguishing hallmark, the clinical presentation vary greatly complicating the diagnosis. In this regard, new classification criteria were jointly published in 2013 by American College of Rheumatology (ACR) and European League Against Rheumatism (EULAR). A recent major development in the classification criteria is improved sensitivity, particularly for detecting early disease. The new criteria allow more cases to be classified as having systemic sclerosis (SSc), which leads to earlier treatment. Moreover it is clinically beneficial in preventing the disease progression with its irreversible fibrosis and organ damage. The aim of this review is to give insight into new classification criteria and current trends in the diagnosis of systemic sclerosis.

  11. Meeting the political and the legislative Copenhagen Criteria, the case of Kosovo

    Directory of Open Access Journals (Sweden)

    LL.M. Rinor Hoxha

    2013-12-01

    Full Text Available The next enlargement of the European Union is predicted to be in the Balkans. Kosovo, a small country of the Balkan Peninsula, which has been declared as an independent state in 2008, aims the membership in EU. Kosovo is currently at the stage of negotiating the Stabilization and Association Agreement with EU. For the membership in EU, candidate countries are required to achieve certain criteria: political, legislative, economic and administrative. The first three are known as the Copenhagen Criteria, whereas the last one as the Madrid Criteria. This paper looks to briefly asses the difficulties of Kosovo in meeting the two Copenhagen Criteria: the political and the legislative one. Although, Kosovo has achieved certain progress related to this matter, this paper presents only the dimensions where Kosovo is lacking in achieving the aforementioned requirements.

  12. The political economy of death and the history of its criteria.

    Science.gov (United States)

    Epstein, Miran

    2009-01-01

    This paper argues for a constitutive link between ecologies of social interests and the social receptivity, if not also the formation, of some recent criteria of death. It maintains that these criteria have been embraced by ecologies that have been dominated by certain economic interests in pronouncing some patients dead. Moreover, the very same ecologies have also embraced philosophical representations of those criteria, but only such that were able to conceal these interests and thereby legitimize and reaffirm their hegemony. Based on this observation, the paper concludes that the current criteria of death and their philosophical representations are ideological constructs in the strict Marxian sense. They may or may not be 'really' true, but they are 'necessarily false' in one respect: they owe their social status to the fact that their self-professed role-pronouncing dead those who are dead-is not in accord with their objective, i.e., social, role-pronouncing dead those who should be dead.

  13. Critical Review of the Material Criteria of Building Sustainability Assessment Tools

    Directory of Open Access Journals (Sweden)

    Jiyoung Park

    2017-01-01

    Full Text Available Comparative analysis of the material criteria embedded in building sustainability assessment tools was performed. The material-related issues were identified, classified, and summarized. A framework, the triple bottom line of sustainability (environment, economy, and society, was used to examine the material assessment criteria, evaluation parameters, and descriptions. The material criteria were evaluated to identify the current features and weaknesses as balanced material assessments for sustainable development. The criteria showed significant differences in their scopes in covering the social and economic aspects beyond the environmental aspect. For comprehensive sustainability assessment purposes, it is essential that adequate attention be paid to all three dimensions. Finally, this paper proposes the indicators of the sustainable material assessment from an analysis of all the material-related items.

  14. The impact of endorsing Spitzer's proposed criteria for PTSD in the forthcoming DSM-V on male and female Veterans.

    Science.gov (United States)

    Miller, Lyndsey N; Chard, Kathleen M; Schumm, Jeremiah A; O'Brien, Carol

    2011-06-01

    This study explored differences between Spitzer's proposed model of posttraumatic stress disorder (PTSD) and the current DSM-IV diagnostic classification scheme in 353 Veterans. The majority of Veterans (89%) diagnosed with PTSD as specified in the DSM-IV also met Spitzer's proposed criteria. Veterans who met both DSM-IV and Spitzer's proposed criteria had significantly higher Clinician Administered PTSD Scale severity scores than Veterans only meeting DSM-IV criteria. Logistic regression indicated that being African American and having no comorbid diagnosis of major depressive disorder or history of a substance use disorder were found to predict those Veterans who met current, but not proposed criteria. These findings have important implications regarding proposed changes to the diagnostic classification criteria for PTSD in the forthcoming DSM-V.

  15. 47 CFR 22.537 - Technical channel assignment criteria.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Technical channel assignment criteria. 22.537... assignment criteria. The rules in this section establish technical assignment criteria for the channels listed in § 22.531. These criteria permit channel assignments to be made in a manner such that reception...

  16. 24 CFR 594.17 - General criteria for competitive selection.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 3 2010-04-01 2010-04-01 false General criteria for competitive... Allocation and Criteria § 594.17 General criteria for competitive selection. (a) Criteria. HUD will use the... (5) The quality of the strategy to increase the capacity of the organization and the...

  17. 40 CFR 227.31 - Applicable marine water quality criteria.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Applicable marine water quality... § 227.31 Applicable marine water quality criteria. Applicable marine water quality criteria means the criteria given for marine waters in the EPA publication “Quality Criteria for Water” as published in 1976...

  18. Student-Focused Assessment Criteria: Thinking through Best Practice

    Science.gov (United States)

    Worth, Nancy

    2014-01-01

    Using results from a survey and focus groups with staff and students, I evaluate best practice for student-focused assessment criteria, including the value of specific assessment criteria, where and when students engage with criteria, the use of exemplars, how assessment criteria connect to feedback and the importance of bringing students more…

  19. Comparison of ICD-10 and Gillberg's Criteria for Asperger Syndrome.

    Science.gov (United States)

    Leekam, Susan; Libby, Sarah; Wing, Lorna; Gould, Judith; Gillberg, Christopher

    2000-01-01

    This study compared the ICD-10 criteria for Asperger syndrome with those suggested by Gillberg with 200 children and adults who met ICD-10 criteria for autism. Comparison indicated only three subjects met ICD-10 criteria for Asperger syndrome whereas 91 met Gillberg's criteria. The discrepancy appeared due to the specific "normal development"…

  20. Potential Impact of DSM-5 Criteria on Autism Spectrum Disorder Prevalence Estimates

    Science.gov (United States)

    Maenner, Matthew J.; Rice, Catherine E.; Arneson, Carrie L.; Cunniff, Christopher; Schieve, Laura A.; Carpenter, Laura A.; Van Naarden Braun, Kim; Kirby, Russell S.; Bakian, Amanda V.; Durkin, Maureen S.

    2014-01-01

    IMPORTANCE The DSM-5 contains revised diagnostic criteria for autism spectrum disorder (ASD) from the DSM-IV-TR. Potential impacts of the new criteria on ASD prevalence are unclear. OBJECTIVE To assess potential effects of the DSM-5 ASD criteria on ASD prevalence estimation by retrospectively applying the new criteria to population-based surveillance data collected for previous ASD prevalence estimation. DESIGN, SETTING, AND PARTICIPANTS Cross-sectional, population-based ASD surveillance based on clinician review of coded behaviors documented in children’s medical and educational evaluations from 14 geographically defined areas in the United States participating in the Autism and Developmental Disabilities Monitoring (ADDM) Network in 2006 and 2008. This study included 8-year-old children living in ADDM Network study areas in 2006 or 2008, including 644 883 children under surveillance, of whom 6577 met surveillance ASD case status based on the DSM-IV-TR. MAIN OUTCOMES AND MEASURES Proportion of children meeting ADDM Network ASD criteria based on the DSM-IV-TR who also met DSM-5 criteria; overall prevalence of ASD using DSM-5 criteria. RESULTS Among the 6577 children classified by the ADDM Network as having ASD based on the DSM-IV-TR, 5339 (81.2%) met DSM-5 ASD criteria. This percentage was similar for boys and girls but higher for those with than without intellectual disability (86.6% and 72.5%, respectively; P DSM-5 ASD criteria but not current ADDM Network ASD case status. Based on these findings, ASD prevalence per 1000 for 2008 would have been 10.0 (95% CI, 9.6–10.3) using DSM-5 criteria compared with the reported prevalence based on DSM-IV-TR criteria of 11.3 (95% CI, 11.0–11.7). CONCLUSIONS AND RELEVANCE Autism spectrum disorder prevalence estimates will likely be lower under DSM-5 than under DSM-IV-TR diagnostic criteria, although this effect could be tempered by future adaptation of diagnostic practices and documentation of behaviors to fit the new

  1. Criteria for measures of quantum correlations

    CERN Document Server

    Brodutch, Aharon

    2011-01-01

    Entanglement does not describe all quantum correlations and several authors have shown the need to go beyond entanglement when dealing with mixed states. Several different measures have sprung up in the literature, for a variety of reasons, To describe quantum correlations; some are known under the collective name quantum discord. Yet, in the same sprit as the criteria for entanglement measures, there is no general mechanism that determines whether a measure of quantum and classical correlations is a proper measure of correlations. This is partially due to the fact that the answer is a bit muddy. In this article we attempt tackle this muddy topic by writing down several criteria for a "good" measure of correlations. We breakup our list into necessary, reasonable, and debatable conditions. We then proceed to prove several of these conditions for generalized measures of quantum correlations. However, not all conditions are met by all measures; we show this via several examples. The reasonable conditions are rel...

  2. Nevada National Security Site Waste Acceptance Criteria

    Energy Technology Data Exchange (ETDEWEB)

    NSTec Environmental Management

    2010-09-03

    This document establishes the U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office (NNSA/NSO) Nevada National Security Site Waste Acceptance Criteria (NNSSWAC). The NNSSWAC provides the requirements, terms, and conditions under which the Nevada National Security Site (NNSS) will accept low-level radioactive waste and mixed low-level waste for disposal. The NNSSWAC includes requirements for the generator waste certification program, characterization, traceability, waste form, packaging, and transfer. The criteria apply to radioactive waste received at the NNSS Area 3 and Area 5 Radioactive Waste Management Complex for disposal. The NNSA/NSO and support contractors are available to assist you in understanding or interpreting this document. For assistance, please call the NNSA/NSO Waste Management Project at (702) 295-7063 or fax to (702) 295-1153.

  3. Nevada National Security Site Waste Acceptance Criteria

    Energy Technology Data Exchange (ETDEWEB)

    NSTec Environmental Management

    2011-01-01

    This document establishes the U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office (NNSA/NSO) Nevada National Security Site Waste Acceptance Criteria (NNSSWAC). The NNSSWAC provides the requirements, terms, and conditions under which the Nevada National Security Site (NNSS) will accept low-level radioactive waste and mixed low-level waste for disposal. The NNSSWAC includes requirements for the generator waste certification program, characterization, traceability, waste form, packaging, and transfer. The criteria apply to radioactive waste received at the NNSS Area 3 and Area 5 Radioactive Waste Management Complex for disposal. The NNSA/NSO and support contractors are available to assist you in understanding or interpreting this document. For assistance, please call the NNSA/NSO Waste Management Project at (702) 295-7063 or fax to (702) 295-1153.

  4. Revised response criteria for malignant lymphoma

    DEFF Research Database (Denmark)

    Cheson, Bruce D; Pfistner, Beate; Juweid, Malik E

    2007-01-01

    PURPOSE: Standardized response criteria are needed to interpret and compare clinical trials and for approval of new therapeutic agents by regulatory agencies. METHODS: The International Working Group response criteria (Cheson et al, J Clin Oncol 17:1244, 1999) were widely adopted, but required...... reassessment because of identified limitations and the increased use of [18F]fluorodeoxyglucose-positron emission tomography (PET), immunohistochemistry (IHC), and flow cytometry. The International Harmonization Project was convened to provide updated recommendations. RESULTS: New guidelines are presented...... incorporating PET, IHC, and flow cytometry for definitions of response in non-Hodgkin's and Hodgkin's lymphoma. Standardized definitions of end points are provided. CONCLUSION: We hope that these guidelines will be adopted widely by study groups, pharmaceutical and biotechnology companies, and regulatory...

  5. Shale Gas Play Screening and Evaluation Criteria

    Institute of Scientific and Technical Information of China (English)

    Michael D. Burnaman; Wenwu Xia; John Shelton

    2009-01-01

    The uniqueness of shale gas plays is contrasted with conventional oil and gas exploration. Based on our ten year history in shale gas exploration, a practical 17 point list of criteria to use for screening shale gas projects and ranking that encompasses geoscience, geochemistry, reservoir engineering, drilling, completions and production operations is developed and explained. Other considerations that will impact shale gas development are identified and discussed. Some key methodologies to incorporate in the evaluation process are also proposed. The outcome of this proposed screening process, if rigorously applied,should quickly identify the projects that have the most likely chance for success for recommendation to management. Examples from active shale gas plays in the United States are used to support these criteria and references to relevant recent publications and presentations are provided.

  6. Report on Criteria for Endocrine Disrupters

    DEFF Research Database (Denmark)

    Holbech, Henrik

    2011-01-01

    This report has been prepared by the Danish Centre on Endocrine Disrupters as a project contracted by the Danish Environmental Protection Agency. The Danish Centre on Endocrine Disrupters is an interdisciplinary scientific network without walls. The main purpose of the Centre is to build and gather...... new knowledge on endocrine disrupters with the focus on providing information requested for the preventive work of the regulatory authorities. The Centre is financed by the Ministry of the Environment and the scientific work programme is followed by an international scientific advisory board....... The overall aim of this project is to provide a science based proposal for criteria for endocrine disrupters. The terms of reference for the project specify elements to be included and/or addressed when developing the criteria (Annex 1). Also, several international reports and papers dealing with assessment...

  7. Index and Indexing Assessment: Criteria and Standards

    Directory of Open Access Journals (Sweden)

    Hassan Ashrafi

    2007-10-01

    Full Text Available Indexing is one of the most important methods of content representation where by assigning descriptors to the documents, their subject content are made known. Since index and indexing are remarkably significant in information retrieval, its quality and evaluation and provision of criteria and standards had always been the mainstay of researchers in this field. Given the fact that Indexing is a complex process, offering definitions, principles and methods could be step towards optimal use of the information. The present study, while offering a capsule definition of index, will investigate the indexing evaluation criteria and would follow it up with a definition of indexing. Finally a number of standards in the field of indexing are presented and would make its conclusions.

  8. AAPT Diagnostic Criteria for Central Neuropathic Pain

    DEFF Research Database (Denmark)

    Widerstrom-Noga, Eva; Loeser, John D.; Jensen, Troels Staehelin

    2017-01-01

    framework can be extended to central pain due to other causes such as traumatic brain injury. The classification of central neuropathic pain is organized according to the AAPT multidimensional framework, specifically (1) core diagnostic criteria; (2) common features; (3) common medical and psychiatric......Central neuropathic pain, which is pain caused by a lesion or disease of the central somatosensory nervous system, is a serious consequence of spinal cord injury, stroke, multiple sclerosis and other conditions affecting the central nervous system. A collaborative effort between the Analgesic......, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks (ACTTION) public-private partnership and the American Pain Society (APS), the ACTTION-APS Pain Taxonomy (AAPT) initiative, invited a working group to develop diagnostic criteria for central neuropathic pain...

  9. Packaging Design Criteria for the MCO Cask

    Energy Technology Data Exchange (ETDEWEB)

    FLANAGAN, B.D.

    2000-08-01

    Approximately 2,100 metric tons of unprocessed, irradiated, nuclear fuel elements are presently stored in the K Basins (including approximately 700 additional elements from the Plutonium-Uranium Extraction Plant, N Reactor, and 327 Laboratory). To permit cleanup of the K Basins and fuel conditioning, the fuel will be transported from the 100 K Area to a Canister Storage Building (CSB) in the 200 East Area. The purpose of this packaging design criteria is to provide criteria for the design, fabrication, and use of a packaging system to transport the large quantities of irradiated nuclear fuel elements positioned within Multi-canister Overpacks. Concurrent with the K Basin cleanup, 72 Shippingport Pressurized Water Reactor Core 2 fuel assemblies will be transported from T Plant to the CSB to provide space at T Plant for K Basin sludge canisters.

  10. Packaging design criteria for the MCO cask

    Energy Technology Data Exchange (ETDEWEB)

    Edwards, W.S.

    1996-04-29

    Approximately 2,100 metric tons of unprocessed, irradiated nuclear fuel elements are presently stored in the K Basins (including possibly 700 additional elements from PUREX, N Reactor, and 327 Laboratory). The basin water, particularly in the K East Basin, contains significant quantities of dissolved nuclear isotopes and radioactive fuel corrosion particles. To permit cleanup of the K Basins and fuel conditioning, the fuel will be transported from the 100 K Area to a Canister Storage Building (CSB) in the 200 East area. In order to initiate K Basin cleanup on schedule, the two-year fuel-shipping campaign must begin by December 1997. The purpose of this packaging design criteria is to provide criteria for the design, fabrication, and use of a packaging system to transport the large quantities of irradiated nuclear fuel elements positioned within Multiple Canister Overpacks.

  11. The Success Criteria of Scientific Pedagogic Activities

    Directory of Open Access Journals (Sweden)

    M. V. Ovchinnikov

    2013-01-01

    Full Text Available The paper considers the problem of scientific pedagogic activity assessment of the higher school academic staff. The existing options of quality estimation are listed along with their deficiencies; the most acceptable in the authors’ opinion being the systematic approach. The latter allows considering almost every aspect of scientific-pedagogic activity. On that ground, the authors recommend the following success estimation criteria: gnostic, projecting, communicative, informational, and organizational. The criteria of work satisfaction and its results are taken into consideration as additional ones. The indicators of each criterion are given demonstrating that the as- sessment can be both internal (subjective and external (objective, denoted in the normative acts. The problem of complex and just quality assessment of scientific- pedagogic activity is quite relevant as it affects the academic staff motivation. The authors believe that the research findings can improve the objectivity of teachers’ work assessment and give way to differentiated approaches to their motivation and stimulation. 

  12. Canine atopic dermatitis diagnostic criteria: evaluation of four sets of published criteria among veterinary students.

    Science.gov (United States)

    Le Roy, Lucile; Le Poder, Sophie; Desquilbet, Loïc; Perrot, Sebastien; Cavana, Paola; Marignac, Geneviève

    2015-01-01

    Canine atopic dermatitis (cAD) is a major teaching point as its diagnosis and treatment are difficult. During 11 weeks, 140 dogs and students (third, fourth, and fifth years) were recruited and paired. One of the four lists of diagnostic criteria was randomly attributed to each student. Concordance results, calculated with Cohen's kappa, ranged from slight (κ=0.07) to moderate (κ=0.53). Favrot's diagnostic criteria received the best results. It has been observed that results are improved with clinical experience. We observed that students often forgot that Favrot's criteria apply only to pruritic dogs and that the fulfillment of the criteria allows only a suspicion, not a diagnosis, of cAD. Primary pruritus and corticosteroid-responsive pruritus were often misunderstood.

  13. Optimum Criteria for Developing Defined Structures

    Directory of Open Access Journals (Sweden)

    Ion IVAN

    2008-01-01

    Full Text Available Basic aspects concerning distributed applications are presented: definition, particularities and importance. For distributed applications linear, arborescent, graph structures are defined with different versions and aggregation methods. Distributed applications have associated structures which through their characteristics influence the costs of the stages in the development cycle and the exploitation costs transferred to each user. The complexity of the defined structures is analyzed. The minimum and maximum criteria are enumerated for optimizing distributed application structures.

  14. Criteria of the Nonsingular H-Matrices

    Institute of Scientific and Technical Information of China (English)

    GAO jian; LIU Futi; HUANG Tingzhu

    2004-01-01

    The nonsingular H-matrices play an important role in the study of the matrix theory and the iterative method of systems of linear equations,etc.It has always been searched how to verify nonsingular H-matrices.In this paper,nonsingular H-matrices is studies by applying diagonally dominant matrices,irreducible diagonally dominant matrices and comparison matrices and several practical criteria for identifying nonsingular H-matrices are obtained.

  15. Quality criteria for electronic publications in medicine.

    Science.gov (United States)

    Schulz, S; Auhuber, T; Schrader, U; Klar, R

    1998-01-01

    This paper defines "electronic publications in medicine (EPM)" as computer based training programs, databases, knowledge-based systems, multimedia applications and electronic books running on standard platforms and available by usual distribution channels. A detailed catalogue of quality criteria as a basis for development and evaluation of EPMs is presented. The necessity to raise the quality level of electronic publications is stressed considering aspects of domain knowledge, software engineering, media development, interface design and didactics.

  16. Empirical Criteria of Superconductivity for Some Oxides

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    The properties of superconductivity of some oxides were investigated by structural parametricdiagrams or pattern recognition with structural chemical parameters. The essential criteria ofsuperconductivity for some oxides have been obtained by using 109 oxides as the training setand seven parameters as features; the results illustrated that the electronegativity difference isthe most important factor among seven parameters. Moreover, the regularity of superconductivetransition temperature Tc for complex oxides is discussed by partial least squares (PL5) method.

  17. Preliminary classification criteria for the cryoglobulinaemic vasculitis

    Science.gov (United States)

    De Vita, S; Soldano, F; Isola, M; Monti, G; Gabrielli, A; Tzioufas, A; Ferri, C; Ferraccioli, G F; Quartuccio, L; Corazza, L; De Marchi, G; Casals, M Ramos; Voulgarelis, M; Lenzi, M; Saccardo, F; Fraticelli, P; Mascia, M T; Sansonno, D; Cacoub, P; Tomsic, M; Tavoni, A; Pietrogrande, M; Zignego, A L; Scarpato, S; Mazzaro, C; Pioltelli, P; Steinfeld, S; Lamprecht, P; Bombardieri, S; Galli, M

    2011-01-01

    Background To develop preliminary classification criteria for the cryoglobulinaemic syndrome or cryoglobulinaemic vasculitis (CV). Methods Study part I developed a questionnaire for CV to be included in the formal, second part (study part II). Positivity of serum cryoglobulins was defined by experts as an essential condition for CV classification. In study part II, a core set of classification items (questionnaire, clinical and laboratory items, as agreed) was tested in three groups of patients and controls—that is, group A (new patients with the CV), group B (controls with serum cryoglobulins but lacking CV) and group C (controls without serum cryoglobulins but with features which can be observed in CV). Results In study part I (188 cases, 284 controls), a positive response to at least two of three selected questions showed a sensitivity of 81.9% and a specificity of 83.5% for CV. This questionnaire was employed and validated in study part II, which included 272 patients in group A and 228 controls in group B. The final classification criteria for CV, by pooling data from group A and group B, required the positivity of questionnaire plus clinical, questionnaire plus laboratory, or clinical plus laboratory items, or all the three, providing a sensitivity of 88.5% and a specificity of 93.6% for CV. By comparing data in group A versus group C (425 controls), the same classification criteria showed a sensitivity 88.5% and a specificity 97.0% for CV. Conclusion Classification criteria for CV were developed, and now need validation. PMID:21571735

  18. Criteria: waste tank isolation and stabilization

    Energy Technology Data Exchange (ETDEWEB)

    Metz, W.P.; Ogren, W.E.

    1976-09-01

    The crystallized Hanford high-level wastes stored in single-shell underground tanks consist of sludges and salt cakes covered with supernatural liquor. Purpose of stabilization and isolation is to reduce the releases and losses as a result of a loss of tank integrity. The tanks will be modified so that no inadvertent liquid additions can be made. Criteria for the isolation and stabilization are given and discussed briefly. (DLC)

  19. Methods for Developing Habitability Design Criteria.

    Science.gov (United States)

    1980-07-01

    Another problem concerned special information , case studies, or informa- tion which is not readily generalized or translated into criteria. Both basic...information (which is already in a prescriptive* format) and various kinds of special information (in a descriptive format) were handled with the same...priority in early activities of the process. This created difficulty because the special information required more careful study to determine if -- and

  20. New criteria for diagnosing Alzheimer's disease

    Directory of Open Access Journals (Sweden)

    Andrei Yuryevich Emelin

    2011-01-01

    Full Text Available Department of Nervous Diseases, S.M. Kirov Military Medical Academy, Saint Petersburg The paper gives an analysis of new diagnostic criteria for different stages of Alzheimer Х s disease (AD, which is proposed by the U.S. National Institute on Aging. It considers possibilities for the early diagnosis of AD, including its preclinical diagnosis using the laboratory and neuroimaging markers beta-amyloid, neuronal damage.

  1. What is in a name? Comparing diagnostic criteria for chronic fatigue syndrome with or without fibromyalgia.

    Science.gov (United States)

    Meeus, Mira; Ickmans, Kelly; Struyf, Filip; Kos, Daphne; Lambrecht, Luc; Willekens, Barbara; Cras, Patrick; Nijs, Jo

    2016-01-01

    The current study had two objectives. (1) to compare objective and self-report measures in patients with chronic fatigue syndrome (CFS) according to the 1994 Center for Disease Control (CDC) criteria, patients with multiple sclerosis (MS), and healthy controls, and (2) to contrast CFS patients who only fulfill CDC criteria to those who also fulfill the criteria for myalgic encephalomyelitis (ME), the 2003 Canadian criteria for ME/CFS, or the comorbid diagnosis of fibromyalgia (FM). One hundred six participants (48 CFS patients diagnosed following the 1994 CDC criteria, 19 MS patients, and 39 healthy controls) completed questionnaires assessing symptom severity, quality of life, daily functioning, and psychological factors. Objective measures consisted of activity monitoring, evaluation of maximal voluntary contraction and muscle recovery, and cognitive performance. CFS patients were screened whether they also fulfilled ME criteria, the Canadian criteria, and the diagnosis of FM. CFS patients scored higher on symptom severity, lower on quality of life, and higher on depression and kinesiophobia and worse on MVC, muscle recovery, and cognitive performance compared to the MS patients and the healthy subjects. Daily activity levels were also lower compared to healthy subjects. Only one difference was found between those fulfilling the ME criteria and those who did not regarding the degree of kinesiophobia (lower in ME), while comorbidity for FM significantly increased the symptom burden. CFS patients report more severe symptoms and are more disabled compared to MS patients and healthy controls. Based on the present study, fulfillment of the ME or Canadian criteria did not seem to give a clinically different picture, whereas a diagnosis of comorbid FM selected symptomatically worse and more disabled patients.

  2. Review of classification criteria for systemic lupus erythematosus.

    Science.gov (United States)

    Petri, Michelle

    2005-05-01

    The American College of Rheumatology classification criteria were devised in 1982. In 1997, the immunologic disorder criterion was revised by a committee (without validation). All 11 criteria in the American College of Rheumatology criteria set have limitations. One of the most important laboratory tests, hypocomplementemia, was excluded entirely. Other classification criteria, emphasizing weighting or recursive partitioning, exist, but they are more cumbersome. Revised criteria are needed, not just for systemic lupus erythematosus, but also for chronic cutaneous lupus.

  3. Comparing new diagnostic criteria of 2010 ACR/EULAR with 1987 ACR criteria in rheumatoid arthritis

    Directory of Open Access Journals (Sweden)

    Fatemeh Shirani

    2017-01-01

    Full Text Available Background: Rheumatoid Arthritis (RA is a chronic inflammatory disease presenting with inflammation, tenderness and destruction of the synovial joints, resulting in severe disability and early death due to complication of disease. Previous diagnostic criteria are not useful for identifying patients who need early treatment. Thus, new diagnostic criteria for faster diagnosis of disease are introduced in 2010. The aim of this study was to compared 1987 ACR (American College of Rheumatology criteria and 2010 ACR/EULAR (European League Against Rheumatism classification criteria for diagnosis of rheumatoid arthritis. Methods: In this Cohort prospective study, patients with early arthritis were evaluated   according to the old and new diagnostic criteria and followed-up every two monthly for one year (2012-2013 in Hazrat-e Rasool University Hospital, Tehran. Inclusion criteria of this study were age more than 18 year and indefinite diagnosis of arthritis. For all of patients physical examination by expert rheumatologist was done and lab data include erythrocyte sedimentation rate (ESR, C-reactive protein (CRP, anti-cyclic citrullinated peptide (Anti-CCP and rheumatoid factor was requested. The sensitivity, specificity, positive and negative predictive values were then determined for each diagnostic criteria. Results: In this study 104 patients including 28 males (26.9% and 76 females (73.1% with the mean age of 44.2±13.7 years were included. At the end of one year follow-up, 82 were diagnosed to have RA while other 22 patients were not categorized as RA. Sensitivity for ESR, CRP, Anti-CCP and rheumatoid factor in 2010 ACR/EULAR criteria was 52%, 19%, 48%, 28% and specificity for them was 45%, 71%, 27%, 79% respectively. Number of small and large joint arthritis were more in patients with Rheumatoid Arthritis (RA rather than other arthritis (P=0.0001. Sensitivity and specificity for small joints involvement was 87% and 54% and for large joints

  4. Acceptance Criteria Framework for Autonomous Biological Detectors

    Energy Technology Data Exchange (ETDEWEB)

    Dzenitis, J M

    2006-12-12

    The purpose of this study was to examine a set of user acceptance criteria for autonomous biological detection systems for application in high-traffic, public facilities. The test case for the acceptance criteria was the Autonomous Pathogen Detection System (APDS) operating in high-traffic facilities in New York City (NYC). However, the acceptance criteria were designed to be generally applicable to other biological detection systems in other locations. For such detection systems, ''users'' will include local authorities (e.g., facility operators, public health officials, and law enforcement personnel) and national authorities [including personnel from the Department of Homeland Security (DHS), the BioWatch Program, the Centers for Disease Control and Prevention (CDC), and the Federal Bureau of Investigation (FBI)]. The panel members brought expertise from a broad range of backgrounds to complete this picture. The goals of this document are: (1) To serve as informal guidance for users in considering the benefits and costs of these systems. (2) To serve as informal guidance for developers in understanding the needs of users. In follow-up work, this framework will be used to systematically document the APDS for appropriateness and readiness for use in NYC.

  5. Autoimmune Hepatitis: Clinical Manifestations and Diagnostic Criteria

    Directory of Open Access Journals (Sweden)

    Ian G Mcfarlane

    2001-01-01

    Full Text Available In 1998, the International Autoimmune Hepatitis Group - a panel of 40 hepatologists and hepatopathologists from 17 countries who have a particular interest in autoimmune hepatitis (AIH - undertook a review, in light of subsequent experience, of the descriptive criteria and diagnostic scoring system that it had proposed in 1993 for the diagnosis of AIH. This review (published in 1999 noted that the original descriptive criteria appeared to be quite robust and required only relatively minor modifications to bring them up to date with developments and experience in diagnostic modalities for liver disease in general. Analysis of published data on the application of the original criteria in nearly 1000 patients revealed that the diagnostic scoring system had an overall diagnostic accuracy of 89.8%, with a sensitivity of 98.0%. Specificity for excluding definite AIH in patients with chronic viral hepatitis and circulating autoantibodies or patients with overlapping cholestatic syndromes was 98% to 100%, but specificity for excluding probable AIH in these disorders ranged from only 60% to 80%. Modifications, including adjustments to the weightings against biochemical and histological cholestatic features, have been made to the scoring system to improve its specificity.

  6. Criteria Assessment Model for Sustainable Product Development

    Science.gov (United States)

    Mohd Turan, Faiz; Johan, Kartina; Hisyamudin Muhd Nor, Nik

    2016-11-01

    The instability in today's market and the ever increasing and emerging demands for mass customized and hybrid products by customers, are driving companies and decision makers to seek for cost effective and time efficient improvements in their product development process. Design concept evaluation which is the end of conceptual design is one of the most critical decision points in product development. It relates to the final success of product development, because poor criteria assessment in design concept evaluation can rarely compensated at the later stages. This has led to real pressure for the adaptation of new developmental architecture and operational parameters to remain competitive in the market. In this paper, a new integrated design concept evaluation based on fuzzy-technique for order preference by similarity to ideal solution (Fuzzy-TOPSIS) is presented, and it also attempts to incorporate sustainability practices in assessing the criteria. Prior to Fuzzy-TOPSIS, a new scale of “Weighting criteria” for survey process is developed to quantify the evaluation criteria. This method will help engineers to improve the effectiveness and objectivity of the sustainable product development. Case example from industry is presented to demonstrate the efficacy of the proposed methodology. The result of the example shows that the new integrated method provides an alternative to existing methods of design concept evaluation.

  7. Inappropriate prescribing: criteria, detection and prevention.

    LENUS (Irish Health Repository)

    O'Connor, Marie N

    2012-06-01

    Inappropriate prescribing is highly prevalent in older people and is a major healthcare concern because of its association with negative healthcare outcomes including adverse drug events, related morbidity and hospitalization. With changing population demographics resulting in increasing proportions of older people worldwide, improving the quality and safety of prescribing in older people poses a global challenge. To date a number of different strategies have been used to identify potentially inappropriate prescribing in older people. Over the last two decades, a number of criteria have been published to assist prescribers in detecting inappropriate prescribing, the majority of which have been explicit sets of criteria, though some are implicit. The majority of these prescribing indicators pertain to overprescribing and misprescribing, with only a minority focussing on the underprescribing of indicated medicines. Additional interventions to optimize prescribing in older people include comprehensive geriatric assessment, clinical pharmacist review, and education of prescribers as well as computerized prescribing with clinical decision support systems. In this review, we describe the inappropriate prescribing detection tools or criteria most frequently cited in the literature and examine their role in preventing inappropriate prescribing and other related healthcare outcomes. We also discuss other measures commonly used in the detection and prevention of inappropriate prescribing in older people and the evidence supporting their use and their application in everyday clinical practice.

  8. [Designation criteria for Leber's hereditary optic neuropathy].

    Science.gov (United States)

    Nakamura, Makoto; Mimura, Osamu; Wakakura, Masato; Inatani, Masaru; Nakazawa, Toru; Shiraga, Fumio

    2015-05-01

    Designation criteria for Leber's hereditary optic neuropathy (LHON) have been established by a working group for retino-choroidal and optic atrophy funded by the Ministry of Health, Labor, and Welfare (MHLW) of Japan in collaboration with the Japanese Neuro-ophthalmology Society. The criteria are composed of three major symptoms and three ancillary test findings. According to the number and the combination of these symptoms and findings, subjects are classified into definite, probable, and possible LHON cases and asymptomatic carriers. The major symptoms include bilateral involvement with a time-lag, a papillomacular bundle atrophy, both characteristic optic disc findings at the acute phase. In the ancillary testings, mitochondrial DNA mutations specific for LHON are detailed with a table listing the mutation loci being attached. To enhance readers' understanding of description of the major symptoms and ancillary test findings, explanatory remarks on 11 parameters are supplemented. The establishment of the criteria facilitates epidemiological survey of LHON by MHLW and contributes to improvement of welfare for patients with LHON in Japan.

  9. Selection criteria for internships in clinical neuropsychology.

    Science.gov (United States)

    Ritchie, David; Odland, Anthony P; Ritchie, Abigail S; Mittenberg, Wiley

    2012-01-01

    Criteria used in the evaluation and selection of applicants for clinical neuropsychology internships were identified by a survey of programs that met guidelines for specialty training. The number of internships that offer training with specialization in clinical neuropsychology has more than doubled during the past 10 years. Supervising neuropsychologists from 75 programs replied to the survey, yielding a 72.8% response rate. Clinical experience in neuropsychological assessment, specialization in clinical neuropsychology during graduate education, personal interview, and letters of recommendation were reported to be the most salient selection criteria. Practica that provide experience with flexible or functional systems assessment approaches at university-affiliated or VA (U.S. Department of Veterans Affairs) medical centers and doctoral curricula that follow International Neuropsychological Society/Division 40 course guidelines, with teaching and supervision provided by neuropsychologists, were preferred prerequisites to internship. These results are consistent with selection criteria reported over a decade ago and indicate continued endorsement of the vertically integrated model of education and training outlined by the Houston Conference on Specialty Education and Training in Clinical Neuropsychology.

  10. Continuity between DSM-5 Categorical Criteria and Traits Criteria for Borderline Personality Disorder.

    Science.gov (United States)

    Bach, Bo; Sellbom, Martin

    2016-08-01

    Borderline personality disorder (BPD) includes a heterogeneous constellation of symptoms operationalized with 9 categorical criteria. As the field of personality disorder (PD) research moves to emphasize dimensional traits in its operationalization, it is important to delineate continuity between the 9 DSM-IV/Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) categorical criteria for BPD and the trait dimensions in DSM-5 Section III. To date, no study has attempted such validation. We examined the associations between the 9 categorical DSM-IV/DSM-5 criteria for BPD and the trait dimensions of the alternative DSM-5 model for PDs in consecutively recruited psychiatric outpatients (N = 142; 68% female; age: mean 29.02, SD 8.38). This was investigated by means of bivariate correlations, followed by multiple logistic regression analysis. The categorical BPD criteria were associated with conceptually related DSM-5 Section III traits (P > 0.001), except for the criterion of chronic feelings of emptiness. Consistent with the proposed traits criteria for BPD in DSM-5 Section III, we found Emotional lability, Anxiousness, Separation insecurity, Depressivity, Impulsivity, Risk taking, and Hostility to capture conceptually coherent BPD categorical criteria, while Suspiciousness was also strongly associated with BPD criteria. At the domain level, this applied to Negative affectivity, Disinhibition, and Psychoticism. Notably, Emotional lability, Impulsivity, and Suspiciousness emerged as unique predictors of BPD (P > 0.05). In addition to the proposed BPD traits criteria, Suspiciousness and features of Psychoticism also augment BPD features. Provided that these findings are replicated in forthcoming research, a modified traits operationalization of BPD is warranted. © The Author(s) 2016.

  11. A practical method for transforming free-text eligibility criteria into computable criteria.

    Science.gov (United States)

    Tu, Samson W; Peleg, Mor; Carini, Simona; Bobak, Michael; Ross, Jessica; Rubin, Daniel; Sim, Ida

    2011-04-01

    Formalizing eligibility criteria in a computer-interpretable language would facilitate eligibility determination for study subjects and the identification of studies on similar patient populations. Because such formalization is extremely labor intensive, we transform the problem from one of fully capturing the semantics of criteria directly in a formal expression language to one of annotating free-text criteria in a format called ERGO annotation. The annotation can be done manually, or it can be partially automated using natural-language processing techniques. We evaluated our approach in three ways. First, we assessed the extent to which ERGO annotations capture the semantics of 1000 eligibility criteria randomly drawn from ClinicalTrials.gov. Second, we demonstrated the practicality of the annotation process in a feasibility study. Finally, we demonstrate the computability of ERGO annotation by using it to (1) structure a library of eligibility criteria, (2) search for studies enrolling specified study populations, and (3) screen patients for potential eligibility for a study. We therefore demonstrate a new and practical method for incrementally capturing the semantics of free-text eligibility criteria into computable form.

  12. Accuracy of ASGE criteria for the prediction of choledocholithiasis

    Directory of Open Access Journals (Sweden)

    Rodrigo M. Narváez-Rivera

    Full Text Available Background/aims: Few studies have validated the performance of guidelines for the prediction of choledocholithiasis (CL. Our objective was to prospectively assess the accuracy of the American Society for Gastrointestinal Endoscopy (ASGE guidelines for the identification of CL. Methods: A two-year prospective evaluation of patients with suspected CL was performed. We evaluated the ASGE guidelines and its component variables in predicting CL. Results: A total of 256 patients with suspected CL were analyzed. Of the 208 patients with high-probability criteria for CL, 124 (59.6% were found to have a stone/sludge at endoscopic retrograde cholangiopancreatography (ERCP. Among 48 patients with intermediate-probability criteria, 21 (43.8% had a stone/sludge. The performance of ASGE high- and intermediate-probability criteria in our population had an accuracy of 59.0% (85.5% sensitivity, 24.3% specificity and 41.0% (14.4% sensitivity, 75.6% specificity, respectively. The mean ERCP delay time was 6.1 days in the CL group and 6.4 days in the group without CL, p = 0.638. The presence of a common bile duct (CBD > 6 mm (OR 2.21; 95% CI, 1.20-4.10, ascending cholangitis (OR 2.37; 95% CI, 1.01-5.55 and a CBD stone visualized on transabdominal US (OR 3.33; 95% CI, 1.48-7.52 were stronger predictors of CL. The occurrence of biliary pancreatitis was a strong protective factor for the presence of a retained CBD stone (OR 0.30; 95% CI, 0.17-0.55. Conclusions: Irrespective of a patient's ASGE probability for CL, the application of current guidelines in our population led to unnecessary performance of ERCPs in nearly half of cases.

  13. DSM disorders and their criteria: how should they inter-relate?

    Science.gov (United States)

    Kendler, K S

    2017-04-04

    conceptual error. It assumes a definitiveness and a literalism about the nature of our criteria that is far beyond our current knowledge. The indexical position with its tentativeness and modesty accurately reflects the current state of our field.

  14. The Montreal Criteria for the Ethical Feasibility of Uterine Transplantation.

    Science.gov (United States)

    Lefkowitz, Ariel; Edwards, Marcel; Balayla, Jacques

    2012-04-01

    Absolute uterine factor infertility (UFI) refers to the refractory causes of female infertility stemming from the anatomical or physiological inability of a uterus to sustain gestation. Today, uterine factor infertility affects 3-5% of the population. Traditionally, although surrogacy and adoption have been the only viable options for females affected by this condition, the uterine transplant is currently under investigation as a potential medical alternative for women who desire to go through the experience of pregnancy. Although animal models have shown promising results, human transplantation cases have only been described in case reports and a successful transplant leading to gestation is yet to occur in humans. Notwithstanding the intricate medical and scientific complexities that a uterine transplant places on the medical minds of our time, ethical questions on this matter pose a similar, if not greater, challenge. In light of these facts, this article attempts to present the ethical issues in the context of experimentation and standard practice which surround this controversial and potentially paradigm-altering procedure; and given these, introduces "The Montreal Criteria for the Ethical Feasibility of Uterine Transplantation", a set of proposed criteria required for a woman to be ethically considered a candidate for uterine transplantation.

  15. Misophonia: current perspectives

    Directory of Open Access Journals (Sweden)

    Cavanna AE

    2015-08-01

    Full Text Available Andrea E Cavanna,1–3 Stefano Seri3,4 1Department of Neuropsychiatry, Birmingham and Solihull Mental Health NHS Foundation Trust and University of Birmingham, Birmingham, 2Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, London, 3School of Life and Health Sciences, Aston Brain Centre, Wellcome Trust Laboratory for MEG Studies, Aston University, 4Children’s Epilepsy Surgery Programme, The Birmingham Children’s Hospital NHS Foundation Trust, Birmingham, UK Abstract: Misophonia is characterized by a negative reaction to a sound with a specific pattern and meaning to a given individual. In this paper, we review the clinical features of this relatively common yet underinvestigated condition, with focus on co-occurring neurodevelopmental disorders. Currently available data on the putative pathophysiology of the condition can inform our understanding and guide the diagnostic process and treatment approach. Tinnitus retraining therapy and cognitive behavior therapy have been proposed as the most effective treatment strategies for reducing symptoms; however, current treatment algorithms should be validated in large population studies. At the present stage, competing paradigms see misophonia as a physiological state potentially inducible in any subject, an idiopathic condition (which can present with comorbid psychiatric disorders, or a symptomatic manifestation of an underlying psychiatric disorder. Agreement on the use of standardized diagnostic criteria would be an important step forward in terms of both clinical practice and scientific inquiry. Areas for future research include phenomenology, epidemiology, modulating factors, neurophysiological underpinnings, and treatment trials. Keywords: misophonia, selective sound sensitivity syndrome, hyperacusis, neurodevelopmental disorders, Tourette syndrome, obsessive-compulsive spectrum

  16. Ocular tuberculosis: current perspectives

    Directory of Open Access Journals (Sweden)

    Shakarchi FI

    2015-11-01

    Full Text Available Faiz I Shakarchi1,21Ibn Al-Haetham Teaching Eye Hospital, 2Department of Opthalmology, Medical College, Al-Mustansiriya University, Baghdad, IraqAbstract: The World Health Organization currently estimates that nearly two billion people, or one-third of the world’s population, are infected by tuberculosis, and that roughly 10% of the infected people are symptomatic. Tuberculosis affects the lungs in 80% of patients, while in the remaining 20% the disease may affect other organs, including the eye. Uveitis can be seen concurrently with tuberculosis, but a direct association is difficult to prove. Ocular tuberculosis is usually not associated with clinical evidence of pulmonary tuberculosis, as up to 60% of extrapulmonary tuberculosis patients may not have pulmonary disease. The diagnosis of tuberculous uveitis is often problematic and in nearly all reported cases, the diagnosis was only presumptive. Tuberculous uveitis is a great mimicker of various uveitis entities and it can be considered in the differential diagnosis of any type of intraocular inflammation. It is still unknown if ocular manifestations result from a direct mycobacterium infection or hypersensitivity reaction and this is reflected on the management of tuberculous uveitis. Prevalence of tuberculosis as an etiology of uveitis may reach up to 10% in endemic areas. Tuberculous uveitis is a vision-threatening disease that inevitably leads to blindness if not properly diagnosed and treated. The aim of this review is to illustrate the various clinical features and management of presumed tuberculous uveitis. The current review focuses on the diagnostic criteria, significance of tuberculin skin test, and use of systemic corticosteroids in the management of tuberculous uveitis as recommended in recent publications.Keywords: tuberculosis, uveitis, choroiditis, tuberculin skin test

  17. 21 CFR 226.1 - Current good manufacturing practice.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Current good manufacturing practice. 226.1 Section...) DRUGS: GENERAL CURRENT GOOD MANUFACTURING PRACTICE FOR TYPE A MEDICATED ARTICLES General Provisions § 226.1 Current good manufacturing practice. (a) The criteria in §§ 226.10 through 226.115,...

  18. 21 CFR 110.5 - Current good manufacturing practice.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Current good manufacturing practice. 110.5 Section...) FOOD FOR HUMAN CONSUMPTION CURRENT GOOD MANUFACTURING PRACTICE IN MANUFACTURING, PACKING, OR HOLDING HUMAN FOOD General Provisions § 110.5 Current good manufacturing practice. (a) The criteria...

  19. Aquatic life water quality criteria derived via the UC Davis method: I. Organophosphate insecticides.

    Science.gov (United States)

    Palumbo, Amanda J; Tenbrook, Patti L; Fojut, Tessa L; Faria, Isabel R; Tjeerdema, Ronald S

    2012-01-01

    robust distribution, and the incorporation of new advances in risk assessment and ecotoxicology. According to the USEPA (1985) method, the data set gathered for malathion would not be sufficient to calculate criteria because it did not contain data for a benthic crustacean. Benthic crustacean data is also required to use a distributional calculation method by the UCDM, but when data is lacking the UCDM provides an alternate calculation method." The resulting criteria are associated with higher, unquantifiable uncertainty, but they are likely more accurate than values generated using static safety factors, which are currently common in risk assessment.

  20. Development of screening guidelines and clinical criteria for predementia Alzheimer's disease : the DESCRIPA study

    NARCIS (Netherlands)

    Visser, P.J.; Verhey, F.R.J.; Boada, M.; Bullock, R.; Deyn, P.P. de; Frisoni, G.B.; Frolich, L.; Hampel, H.; Jolles, J.; Jones, R.; Minthon, L.; Nobili, F.; Olde Rikkert, M.G.M.; Ousset, P.J.; Rigaud, A.S.; Scheltens, P.; Soininen, H.; Spiru, L.; Touchon, J.; Tsolaki, M.; Vellas, B.; Wahlund, L.O.; Wilcock, G.; Winblad, B.

    2008-01-01

    BACKGROUND: There is an urgent need to identify subjects with Alzheimer's disease (AD) in the predementia phase, but validated diagnostic approaches are currently lacking. In this paper, we present the background, design and methods of a study, which aims to develop clinical criteria for predementia

  1. Wittgenstein's Contextualist Approach to Judging "Sound" Teaching: Escaping Enthrallment in Criteria-Based Assessments

    Science.gov (United States)

    Stickney, Jeff Alan

    2009-01-01

    Comparing the early, analytic attempt to define "sound" teaching with the current use of criteria-based rating schemes, Jeff Stickney turns to Wittgenstein's holistic, contextualist approach to judging teaching against its complex "background" within our "form of life." To exemplify this approach, Stickney presents cases of classroom practice…

  2. International Processes on Criteria and Indicators for Sustainable Forest Management and their Influences on China

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Currently more attention has been paid to sustainable forest management (SFM) all over the world. The paper gives the presentation of criteria and indicators (C & I) for SFM at international, national, regional and management unit levels. Under the international framework, the paper summarizes the developing situation of C & I for SFM in China and gives the suggestion on how to promote its development.

  3. Standards and standardization in mastocytosis: Consensus statements on diagnostics, treatment recommendations and response criteria

    NARCIS (Netherlands)

    Valent, P.; Akin, C.; Escribano, L.; Fodinger, M.; Hartmann, K.; Brockow, K.; Castells, M.; Sperr, W.R.; Kluin-Nelemans, Hanneke; Hamdy, N.A.T.; Lortholary, O.; Robyn, J.; van Doormaal, J.; Sotlar, K.; Hauswirth, A.W.; Arock, M.; Hermine, O.; Hellmann, A.; Triggiani, M.; Niedoszytko, M.; Schwartz, L.B.; Orfao, A.; Horny, H.P.; Metcalfe, D.D.

    2007-01-01

    Although a classification for mastocytosis and diagnostic criteria are available, there remains a need to define standards for the application of diagnostic tests, clinical evaluations, and treatment responses. To address these demands, leading experts discussed current issues and standards in masto

  4. Coeliac disease diagnosis: espghan 1990 Criteria or need for a change? Results of a questionnaire

    DEFF Research Database (Denmark)

    Ribes-Koninckx, C; Mearin, Ml; Korponay-Szabó, Ir;

    2012-01-01

    of current criteria for CD diagnosis. METHODS:: Questionnaires were distributed to experienced PG (ESPGHAN members) via internet. RESULTS:: Overall, 95 valid questionnaires were available for analysis, pertaining to 28 different countries, with the majority of responders treating CD patients for more than 15...

  5. Update on US EPA’s Revision to the 1985 Guidelines for Deriving Aquatic Life Criteria

    Science.gov (United States)

    National Water Quality Criteria for the Protection of Aquatic Organisms and Their Uses (Stephan et al. 1985), to reflect the current state-of-the-science for aquatic effects assessments. Following a 2015 public meeting soliciting early input from the scientific community, EPA dec...

  6. Standards and standardization in mastocytosis : Consensus statements on diagnostics, treatment recommendations and response criteria

    NARCIS (Netherlands)

    Valent, P.; Akin, C.; Escribano, L.; Foedinger, M.; Hartmann, K.; Brockow, K.; Castells, M.; Sperr, W. R.; Kluin-Nelemans, H. C.; Hamdy, N. A. T.; Lortholary, O.; Robyn, J.; van Doormaal, J.; Sotlar, K.; Hauswirth, A. W.; Arock, M.; Hermine, O.; Hellmann, A.; Triggiani, M.; Niedoszytko, M.; Schwartz, L. B.; Orfao, A.; Horny, H.-P.; Metcalfe, D. D.

    2007-01-01

    Although a classification for mastocytosis and diagnostic criteria are available, there remains a need to define standards for the application of diagnostic tests, clinical evaluations, and treatment responses. To address these demands, leading experts discussed current issues and standards in masto

  7. Wittgenstein's Contextualist Approach to Judging "Sound" Teaching: Escaping Enthrallment in Criteria-Based Assessments

    Science.gov (United States)

    Stickney, Jeff Alan

    2009-01-01

    Comparing the early, analytic attempt to define "sound" teaching with the current use of criteria-based rating schemes, Jeff Stickney turns to Wittgenstein's holistic, contextualist approach to judging teaching against its complex "background" within our "form of life." To exemplify this approach, Stickney presents cases of classroom practice…

  8. The Value of Fidelity of Implementation Criteria to Evaluate School-Based Science Curriculum Innovations

    Science.gov (United States)

    Lee, Yew-Jin; Chue, Shien

    2013-01-01

    School-based curriculum innovations, including those in science education, are usually not adequately evaluated, if at all. Furthermore, current procedures and instruments for programme evaluations are often unable to support evidence-based decision-making. We suggest that adopting fidelity of implementation (FOI) criteria from healthcare research…

  9. Functional Design Criteria plutonium stabilization and handling (PUSH) project W-460

    Energy Technology Data Exchange (ETDEWEB)

    NELSON, D.W.

    1999-09-02

    This Functional Design Criteria (FDC) contains information to guide the design of the Stabilization and Packaging Equipment necessary to oxidize and package the remaining plutonium-bearing Special Nuclear Materials (SNM) currently in the Plutonium Finishing Plant (PFP) inventory. The FDC also guides the design of vault modifications to allow storage of 3013 packages of stabilized SNM for up to 50 years.

  10. Equilibrium selection in cheap talk games: ACDC rocks when other criteria remain silent

    NARCIS (Netherlands)

    de Groot Ruiz, A.; Offerman, T.; Onderstal, S.

    2010-01-01

    Currently no refinement exists that successfully selects equilibria across a wider range of Cheap Talk games. We propose a generalization of criteria based on credible deviations, such as neologism proofness and announcement proofness. According to our Average Credible Deviation Criterion (ACDC), th

  11. Characteristics of binge eating disorder in relation to diagnostic criteria

    Directory of Open Access Journals (Sweden)

    Wilfley DE

    2016-08-01

    Full Text Available Denise E Wilfley,1 Leslie Citrome,2 Barry K Herman3 1Department of Psychiatry, Washington University School of Medicine, St Louis, MO, 2Department of Psychiatry & Behavioral Sciences, New York Medical College, Valhalla, NY, 3Global Medical Affairs, Shire, Lexington, MA, USA Abstract: The objective of this review was to examine the evidentiary basis for binge eating disorder (BED with reference to the Diagnostic and Statistical Manual of Mental Disorders – Fifth Edition (DSM-5 diagnostic criteria for BED. A PubMed search restricted to titles and abstracts of English-language reviews, meta-analyses, clinical trials, randomized controlled trials, journal articles, and letters using human participants was conducted on August 7, 2015, using keywords that included “binge eating disorder,” DSM-5, DSM-IV, guilt, shame, embarrassment, quantity, psychological, behavior, and “shape and weight concerns.” Of the 257 retrieved publications, 60 publications were considered relevant to discussions related to DSM-5 diagnostic criteria and were included in the current review, and 20 additional references were also included on the basis of the authors’ knowledge and/or on a review of the reference lists from relevant articles obtained through the literature search. Evidence supports the duration/frequency criterion for BED and the primary importance of loss of control and marked distress in identifying individuals with BED. Although overvaluation of shape/weight is not a diagnostic criterion, its relationship to the severity of BED psychopathology may identify a unique subset of individuals with BED. Additionally, individuals with BED often exhibit a clinical profile consisting of psychiatric (eg, mood, obsessive–compulsive, and impulsive disorders and medical (eg, gastrointestinal symptoms, metabolic syndrome, and type 2 diabetes comorbidities and behavioral profiles (eg, overconsumption of calories outside of a binge eating episode and emotional

  12. PWR-2 Blanket Fuel Assembly Removal Safety Basis Criteria Document

    Energy Technology Data Exchange (ETDEWEB)

    BUSHORE, R.P.

    2001-01-22

    This criteria document describes the proposed format, content, and schedule for the preparation of an amendment to the Interim Safety Basis for Solid Waste Facilities (T Plant) (ISB), (HNF-SD-WM-ISB-006), and to the T Plant Interim Operational Safety Requirements (IOSR) (''F-SD-WM-TSR-003). The amendments to these documents are intended to authorize removal of spent nuclear fuel (SNF) assemblies from the spent fuel pool in the Solid Waste Treatment Facility 221-T canyon for interim storage in the Canister Storage Building (CSB). The amendments will include a stand-alone safety assessment as well as revisions to these safety documents as needed to reflect the changes in work scope not currently authorized to accomplish the expected end-state of the Fuel Removal Project for the 221-T Facility.

  13. INTEGRAL CRITERIA FOR EVALUATION OF SCIENTIFIC AND TECHNICAL RESEARCH

    Directory of Open Access Journals (Sweden)

    Stanislav Nazarevich

    2015-09-01

    Full Text Available In the paper, we develop approaches to the estimation of production enterprises based on the criteria of classification of products, goods and services to innovative products. Developed their qualitative scale for interpreting the results of the evaluation, blind spots, which were not included in the intervals, are compensated by the use of fuzzy sets. In the presented method uses integral criterion based on fuzzy accessory products specific form. The obtained numerical values of the integral criterion reflect the adequacy of the technical characteristics to determine the form of new products, as well as identifying the characteristics of the gap to peers and benchmarks. The technique is applicable to the assessment processes of innovation and competitiveness of new and current products, as well as in dealing with the definition of the innovative features of the new products.

  14. Post-load hyperglycaemia and diagnostic criteria for diabetes

    Institute of Scientific and Technical Information of China (English)

    Qing Qiao

    2008-01-01

    The evolution of 2 h post-load glucose tolerance test for diagnosis of diabetes and its clinical implication was reviewed and discussed.Post-load hyperglycemia is a risk factor for both micro-and macro-vascular diseases.According to its relationship with retinopathy,the current cut-off values for diabetes was defined since 1979.Recently,strong evidence has shown that post-load hyperglycemia is also an important risk factor for cardiovascular disease(CVD),the relation is linear and no a threshold was found.There are large discrepancies between fasting and 2 h glucose criteria in the classification of diabetes and impaired glucose tolerance(IGT)/impaired fasting glucose(IFG).For early diagnosis and intervention administrating a 2 h OGTT to suspect individuals is necessary.

  15. The NIMH Research Domain Criteria Initiative: Background, Issues, and Pragmatics.

    Science.gov (United States)

    Kozak, Michael J; Cuthbert, Bruce N

    2016-03-01

    This article describes the National Institute of Mental Health's Research Domain Criteria (RDoC) initiative. The description includes background, rationale, goals, and the way the initiative has been developed and organized. The central RDoC concepts are summarized and the current matrix of constructs that have been vetted by workshops of extramural scientists is depicted. A number of theoretical and methodological issues that can arise in connection with the nature of RDoC constructs are highlighted: subjectivism and heterophenomenology, desynchrony and theoretical neutrality among units of analysis, theoretical reductionism, endophenotypes, biomarkers, neural circuits, construct "grain size," and analytic challenges. The importance of linking RDoC constructs to psychiatric clinical problems is discussed. Some pragmatics of incorporating RDoC concepts into applications for NIMH research funding are considered, including sampling design.

  16. Criteria evaluation for cleanliness testing phase 0

    Energy Technology Data Exchange (ETDEWEB)

    Meltzer, Michael [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Koester, Carolyn [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Stefanni, Chris [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    1999-02-04

    The Boeing Company (Boeing) contracted with Lawrence Livermore National Laboratory (LLNL) to develop criteria for evaluating the efficacy of its parts cleaning processes. In particular, LLNL and Boeing are attempting to identify levels of contamination that lead to parts failures. Sufficient contamination to cause impairment of anodizing, alodining, painting, or welding operations is considered a "part failure." In the "Phase 0" part of the project that was recently completed, preliminary analyses of aluminum substrates were performed as a first step in determining suitable cleanliness criteria for actual Boeing parts made from this material. A wide spread of contamination levels was specified for the Phase 0 test coupons, in the hopes of finding a range in which an appropriate cleanliness specification might lie. It was planned that, based on the results of the Phase 0 testing, further more detailed analyses ("Phase 1 testing") would be performed in order to more accurately identify the most appropriate criteria. For the Phase 0 testing, Boeing supplied LLNL with 3" x 6" and 3" x 10" aluminum test panels which LLNL contaminated with measured amounts of typical hydrocarbon substances encountered in Boeing' s fabrication operations. The panels were then subjected by Boeing to normal cleaning procedures, after which they went through one of the following sets of operations: l anodizing and primer painting . alodining (chromating) and primer painting l welding The coatings or welds were then examined by both Boeing and LLNL to determine whether any of the operations were impaired, and whether there was a correlation between contamination level and damage to the parts. The experimental approach and results are described in detail.

  17. Diagnostic criteria of acute rheumatic fever.

    Science.gov (United States)

    Burke, Rebecca J; Chang, Christopher

    2014-01-01

    Acute rheumatic fever is an inflammatory sequela of Group A Streptococcal pharyngitis that affects multiple organ systems. The incidence of acute rheumatic fever has been declining even before the use of antibiotics became widespread, however the disease remains a significant cause of morbidity and mortality in children, particularly in developing countries and has been estimated to affect 19 per 100,000 children worldwide. Acute rheumatic fever is a clinical diagnosis, and therefore subject to the judgment of the clinician. Because of the variable presentation, the Jones criteria were first developed in 1944 to aid clinicians in the diagnosis of acute rheumatic fever. The Jones criteria have been modified throughout the years, most recently in 1992 to aid clinicians in the diagnosis of initial attacks of acute rheumatic fever and to minimize overdiagnosis of the disease. Diagnosis of acute rheumatic fever is based on the presence of documented preceding Group A Streptococcal infection, in addition to the presence of two major manifestations or one major and two minor manifestations of the Jones criteria. Without documentation of antecedent Group A Streptococcal infection, the diagnosis is much less likely except in a few rare scenarios. Carditis, polyarthritis and Sydenham's chorea are the most common major manifestations of acute rheumatic fever. However, despite the predominance of these major manifestations of acute rheumatic fever, there can be significant overlap with other disorders such as Lyme disease, serum sickness, drug reactions, and post-Streptococcal reactive arthritis. This overlap between disease processes has led to continued investigation of the pathophysiology as well as development of new biomarkers and laboratory studies to aid in the diagnosis of acute rheumatic fever and distinction from other disease processes.

  18. Explicit criteria for prioritization of cataract surgery

    Directory of Open Access Journals (Sweden)

    Escobar Antonio

    2006-03-01

    Full Text Available Abstract Background Consensus techniques have been used previously to create explicit criteria to prioritize cataract extraction; however, the appropriateness of the intervention was not included explicitly in previous studies. We developed a prioritization tool for cataract extraction according to the RAND method. Methods Criteria were developed using a modified Delphi panel judgment process. A panel of 11 ophthalmologists was assembled. Ratings were analyzed regarding the level of agreement among panelists. We studied the effect of all variables on the final panel score using general linear and logistic regression models. Priority scoring systems were developed by means of optimal scaling and general linear models. The explicit criteria developed were summarized by means of regression tree analysis. Results Eight variables were considered to create the indications. Of the 310 indications that the panel evaluated, 22.6% were considered high priority, 52.3% intermediate priority, and 25.2% low priority. Agreement was reached for 31.9% of the indications and disagreement for 0.3%. Logistic regression and general linear models showed that the preoperative visual acuity of the cataractous eye, visual function, and anticipated visual acuity postoperatively were the most influential variables. Alternative and simple scoring systems were obtained by optimal scaling and general linear models where the previous variables were also the most important. The decision tree also shows the importance of the previous variables and the appropriateness of the intervention. Conclusion Our results showed acceptable validity as an evaluation and management tool for prioritizing cataract extraction. It also provides easy algorithms for use in clinical practice.

  19. Multi-criteria model to support decision-making for the remediation of urban areas

    Energy Technology Data Exchange (ETDEWEB)

    De Luca, Christiano; Lopes, Ricardo T., E-mail: christiano_luca@hotmail.com, E-mail: ricardo@lin.ufrj.br [Coordenacao dos Programas de Pos-Graduacao em Engenharia (COPPE/UFRJ), Rio de Janeiro, RJ (Brazil). Programa de Engenharia Nuclear; Rochedo, Elaine R.R., E-mail: elainerochedo@gmail.com [Instituto de Radioprotecao e Dosimetria (IRD/CNEN-RJ), Rio de Janeiro, RJ (Brazil); Silva, Diogo N.G.; Guimaraes, Jean R.D., E-mail: diogons@gmail.com, E-mail: jeanrdg@biof.ufrj.br [Universidade Federal do Rio de Janeiro (UFRJ), RJ (Brazil). Instituto de Biofisica Carlos Chagas Filho; Rochedo, Pedro R.R., E-mail: rochedopedro@gmail.com [Coordenacao dos Programas de Pos-Graduacao em Engenharia (COPPE/UFRJ), Rio de Janeiro, RJ (Brazil). Programa de de Planejamento Energetico; Wasserman, Maria Angelica V., E-mail: mwasserman@ien.gov.br [Instituto de Engenharia Nuclear (IEN/CNEN-RJ), Rio de Janeiro, RJ (Brazil)

    2015-07-01

    Under the environmental modeling Project of radioecology research area of IRD (CNEN), several tools have been developed to support post-emergency activities. Currently, a multi-criteria model is in development with the aim of supporting decision-making processes under the radiological protection point of view. At this stage, we are focusing on the decontamination of urban areas. The model includes five calculation modules: (1) averted doses to the public due to remediation procedures; (2) occupational exposure of remediation workers; (3) properties of the wastes generated by a remediation procedure; (4) classification of each procedure for a specific urban scenario based on previously calculated quantities; and, (5) multi-criteria rank calculation. The classification of procedures is based on two types of criteria previously defined, both also included as input data of the model. The first type, called Subjective Criteria, is based on experts' opinions collected through questionnaires. The second type, called Technical Criteria, is calculated according to the outputs of the three first modules of the program. The output of the model is a rank order list indicating the priority of procedures to use for each different type of urban environment. The use of results based on criteria and methods developed previously to the occurrence of a contamination event intends not only to provide an input to decision-making processes but also to improve public confidence on authorities responsible for the remediation decisions. (author)

  20. Developing Sound Exposure Criteria for Fishes.

    Science.gov (United States)

    Hawkins, Anthony D; Popper, Arthur N

    2016-01-01

    In assessing the impact of aquatic developments, it is important to evaluate whether accompanying underwater sounds might have adverse effects on fishes. Risk assessment can then be used to evaluate new and existing technologies for effective prevention, control, or mitigation of impacts. It is necessary to know the levels of sound that may cause potential harm to different species from different sources as well as those levels that are likely to be of no consequence. The development and use of impact criteria are still at an early stage for fishes.

  1. Exponential Stability Criteria for Nonautonomous Difference Systems

    Directory of Open Access Journals (Sweden)

    Rigoberto Medina

    2014-01-01

    Full Text Available The aim of this paper is to characterize the exponential stability of linear systems of difference equations with slowly varying coefficients. Our approach is based on the generalization of the freezing method for difference equations combined with new estimates for the norm of bounded linear operators. The main novelty of this work is that we use estimates for the absolute values of entries of a matrix-valued function, instead of bounds on its eigenvalues. By this method, new explicit stability criteria for linear nonautonomous systems are derived.

  2. [Ultrasound criteria of a meniscus lesion].

    Science.gov (United States)

    Sohn, C; Casser, H R; Swobodnik, W

    1990-04-01

    The tear in the meniscus interrupts the outline at which the sound-wave energy is reflected. This means that the sonogram shows an echo-rich, light reflection pattern. Degeneration also shows up as an echo-rich area, reflecting greater density of the tissue in the meniscus. This has been confirmed by experimental examination of knees of corpses, and also by clinical experience based on more than 2000 sonograms of the meniscus. A quota of more than 90% correct diagnoses can be obtained if the proper criteria are observed in case of a lesion of the meniscus, and if the technical equipment is adequate and the examiner has acquired sufficient skill.

  3. Qualitative vs. quantitative atopic dermatitis criteria

    DEFF Research Database (Denmark)

    Andersen, R M; Thyssen, J P; Maibach, H I

    2016-01-01

    on the importance of atopic features - subjective, objective, and those derived from laboratory tests - the new partly promising AD biomarkers. 'Atopy', introduced in 1923, denoted 'the sense of a strange disease without a precise place in the body'. A decade later, Sulzberger and Hill, first defined 'atopic...... to well embrace various atopic phenotypes. Pruritus, xerosis, typical morphology/distribution of dermatitis and tendency to a relapsing/chronic course are common basic features in AD criteria, whereas skin sensitivity, heredity and various ill-defined atopic stigmata also seem to comprise the atopic...

  4. Comparison of Prediction-Error-Modelling Criteria

    DEFF Research Database (Denmark)

    Jørgensen, John Bagterp; Jørgensen, Sten Bay

    2007-01-01

    is a realization of a continuous-discrete multivariate stochastic transfer function model. The proposed prediction error-methods are demonstrated for a SISO system parameterized by the transfer functions with time delays of a continuous-discrete-time linear stochastic system. The simulations for this case suggest......Single and multi-step prediction-error-methods based on the maximum likelihood and least squares criteria are compared. The prediction-error methods studied are based on predictions using the Kalman filter and Kalman predictors for a linear discrete-time stochastic state space model, which...... computational resources. The identification method is suitable for predictive control....

  5. Gout Classification Criteria: Update and Implications

    Science.gov (United States)

    Vargas-Santos, Ana Beatriz; Taylor, William J.

    2016-01-01

    Gout is the most common inflammatory arthritis, with a rising prevalence and incidence worldwide. There has been a resurgence in gout research, fueled, in part, by a number of advances in pharmacologic therapy for gout. The conduct of clinical trials and other observational research in gout requires a standardized and validated means of assembling well-defined groups of patients with gout for such research purposes. Recently, an international collaborative effort that involved a data-driven process with state-of-the art methodology supported by the American College of Rheumatology and the European League Against Rheumatism led to publication of new gout classification criteria. PMID:27342957

  6. Organic farming and multi-criteria decisions

    DEFF Research Database (Denmark)

    Christensen, Tove; Olsen, Søren Bøye; Dubgaard, Alex;

    Organic food production is a sphere where decision making is multi-facetted and complex. This applies to producers, political decision makers and consumers alike. This paper provides an overview of the economic methods that can aid such multi criteria decision making. We first provide an outline...... studies on organic farming. Based on this review we provide directional markers for future research where MCA may possibly be applied and adapted in order to provide useful knowledge and support for decision makers in the context of organic farming....

  7. The challenge of sustainable building renovation: assessment of current criteria and future outlook

    OpenAIRE

    Pombo Rodilla, Olatz; Rivela Carballal, Beatriz; Neila Gonzalez, Francisco Javier

    2015-01-01

    Artículo publicado en un número especial dedicado a la sostenibilidad. Se realiza un análisis crítico de las evaluación de la sostenibilidad en la rehabilitación y se plantea la perspectiva futura en este ámbito.

  8. [Contemporary criteria of the diagnosis and current recommendations for nutritional therapy in anorexia nervosa].

    Science.gov (United States)

    Skrypnik, Damian; Bogdański, Paweł; Musialik, Katarzyna; Skrypnik, Katarzyna

    2014-05-01

    The basic criterion for the diagnosis of anorexia (AN - anorexia nervosa) by ICD-10 (International Classification of Diseases, version 10) is the body weight less than 15% of the expected normal body weight. According to DSM-IV (Diagnostic and Statistical Manual for Mental Disorders, version IV) the basic feature of AN is a refusal to maintain body weight equal or greater than the minimal normal weight. The prevalence of anorexia nervosa is 0.3-0.5% or even 1.3-3.7% if include pre-anorexic states (eg. the phenomenon of pro-ana). The main feature of anorexia is a reduction of caloric intake. According to the recommendations of the American Psychiatric Association (APA) for nutritional treatment of patients with AN the main goals in therapy of AN are: restoration of body weight, normalization of eating patterns, achievement a normal feeling of hunger and satiety and correction of the consequences of improper nutrition. APA suggests that achievable weight gain is about 0.9-1.4 kg per week in the case of hospitalized patients and approximately 0.23-0.45 kg per week in the case of outpatients. During the nutritional treatment of AN numerous side effects including anxiety, phobia, occurrence of obsessive thoughts and compulsive behavior, suicidal thoughts and intentions may occur. According to National Institute for Clinical Excellence (NICE) the most important goal of AN therapy is weight gain in the range of 0.5-1 kg per week in hospitalized patients and 0.5 kg per week for outpatients. A person suffering from anorexia in the initial period of nutritional treatment spends twice more energy to maintain elevated body temperature, which significantly increases during the night rest. This phenomenon is called nocturnal hyperthermia and has a negative effect on the healing process. "Refeeding syndrome" is an adverse effect of nutritional treatment in anorexia. It is caused by too rapid nutrition in a patient suffering from chronic starvation. It can endanger the patient's life.

  9. Habitat-based PCB environmental quality criteria for the protection of endangered killer whales (Orcinus orca).

    Science.gov (United States)

    Alava, Juan José; Ross, Peter S; Lachmuth, Cara; Ford, John K B; Hickie, Brendan E; Gobas, Frank A P C

    2012-11-20

    The development of an area-based polychlorinated biphenyl (PCB) food-web bioaccumulation model enabled a critical evaluation of the efficacy of sediment quality criteria and prey tissue residue guidelines in protecting fish-eating resident killer whales of British Columbia and adjacent waters. Model-predicted and observed PCB concentrations in resident killer whales and Chinook salmon were in good agreement, supporting the model's application for risk assessment and criteria development. Model application shows that PCB concentrations in the sediments from the resident killer whale's Critical Habitats and entire foraging range leads to PCB concentrations in most killer whales that exceed PCB toxicity threshold concentrations reported for marine mammals. Results further indicate that current PCB sediment quality and prey tissue residue criteria for fish-eating wildlife are not protective of killer whales and are not appropriate for assessing risks of PCB-contaminated sediments to high trophic level biota. We present a novel methodology for deriving sediment quality criteria and tissue residue guidelines that protect biota of high trophic levels under various PCB management scenarios. PCB concentrations in sediments and in prey that are deemed protective of resident killer whale health are much lower than current criteria values, underscoring the extreme vulnerability of high trophic level marine mammals to persistent and bioaccumulative contaminants.

  10. A critical review of “Internet addiction” criteria with suggestions for the future

    Science.gov (United States)

    VAN ROOIJ, ANTONIUS J.; PRAUSE, NICOLE

    2014-01-01

    Aims: In the last 5 years a deluge of articles on the topic of Internet addiction (IA) has proposed many candidate symptoms as evidence of this proposed disease. We critically reviewed the current approach to the measurement and identification of this new excessive behavior syndrome. Methods: Three popular models of IA were discussed: Griffith’s components model; Young’s Internet Addiction Test (IAT); and the criteria by Tao et al. (2010). We selected these models because they are widely cited and propose specific criteria for IA disorder. Our approach is not meant to provide an exhaustive review, but to discuss and critique the most salient trends in the field. Results: The models of Internet addiction share some criteria, including feeling a loss of control over Internet use; ensuing psychological, social, or professional conflict or problems; and preoccupation when not using the Internet. Other criteria inconsistently mentioned include: mood management, tolerance, withdrawal, and craving/anticipation. The models studied here share the assumption that the Internet can produce a qualitative shift to a diseased state in humans. Conclusions: We critically discussed the above criteria and concluded that the evidence base is currently not strong enough to provide support for an Internet addiction disorder. Future research areas are suggested: (1) Focusing on common impaired dimensions, (2) exploring neuroimaging as a model building tool, and (3) identifying shifts in the rewarding aspects of Internet use. Given the lack of consensus on the subject of Internet addiction, a focus on problem behaviors appears warranted. PMID:25592305

  11. A critical review of "Internet addiction" criteria with suggestions for the future.

    Science.gov (United States)

    Van Rooij, Antonius J; Prause, Nicole

    2014-12-01

    In the last 5 years a deluge of articles on the topic of Internet addiction (IA) has proposed many candidate symptoms as evidence of this proposed disease. We critically reviewed the current approach to the measurement and identification of this new excessive behavior syndrome. Three popular models of IA were discussed: Griffith’s components model; Young’s Internet Addiction Test (IAT); and the criteria by Tao et al. (2010). We selected these models because they are widely cited and propose specific criteria for IA disorder. Our approach is not meant to provide an exhaustive review, but to discuss and critique the most salient trends in the field. The models of Internet addiction share some criteria, including feeling a loss of control over Internet use; ensuing psychological, social, or professional conflict or problems; and preoccupation when not using the Internet. Other criteria inconsistently mentioned include: mood management, tolerance, withdrawal, and craving/anticipation. The models studied here share the assumption that the Internet can produce a qualitative shift to a diseased state in humans. We critically discussed the above criteria and concluded that the evidence base is currently not strong enough to provide support for an Internet addiction disorder. Future research areas are suggested: (1) Focusing on common impaired dimensions, (2) exploring neuroimaging as a model building tool, and (3) identifying shifts in the rewarding aspects of Internet use. Given the lack of consensus on the subject of Internet addiction, a focus on problem behaviors appears warranted.

  12. Validity of proposed DSM-5 diagnostic criteria for nicotine use disorder: results from 734 Israeli lifetime smokers

    Science.gov (United States)

    Shmulewitz, D.; Wall, M.M.; Aharonovich, E.; Spivak, B.; Weizman, A.; Frisch, A.; Grant, B. F.; Hasin, D.

    2013-01-01

    Background The fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) proposes aligning nicotine use disorder (NUD) criteria with those for other substances, by including the current DSM fourth edition (DSM-IV) nicotine dependence (ND) criteria, three abuse criteria (neglect roles, hazardous use, interpersonal problems) and craving. Although NUD criteria indicate one latent trait, evidence is lacking on: (1) validity of each criterion; (2) validity of the criteria as a set; (3) comparative validity between DSM-5 NUD and DSM-IV ND criterion sets; and (4) NUD prevalence. Method Nicotine criteria (DSM-IV ND, abuse and craving) and external validators (e.g. smoking soon after awakening, number of cigarettes per day) were assessed with a structured interview in 734 lifetime smokers from an Israeli household sample. Regression analysis evaluated the association between validators and each criterion. Receiver operating characteristic analysis assessed the association of the validators with the DSM-5 NUD set (number of criteria endorsed) and tested whether DSM-5 or DSM-IV provided the most discriminating criterion set. Changes in prevalence were examined. Results Each DSM-5 NUD criterion was significantly associated with the validators, with strength of associations similar across the criteria. As a set, DSM-5 criteria were significantly associated with the validators, were significantly more discriminating than DSM-IV ND criteria, and led to increased prevalence of binary NUD (two or more criteria) over ND. Conclusions All findings address previous concerns about the DSM-IV nicotine diagnosis and its criteria and support the proposed changes for DSM-5 NUD, which should result in improved diagnosis of nicotine disorders. PMID:23312475

  13. Poor mobilizer: a retrospective study on proven and predicted incidence according to GITMO criteria.

    Science.gov (United States)

    Piccirillo, Nicola; Vacca, Michele; Lanti, Alessandro; Ipsevich, Francesco; Maresca, Maddalena; Fiorelli, Elena; Bianchi, Maria; Adorno, Gaspare; Pierelli, Luca; Majolino, Ignazio; Leone, Giuseppe; Zini, Gina

    2012-10-01

    The Italian Group for Bone Marrow Transplantation (Gruppo Italiano Trapianto di Midollo Osseo, GITMO) recently formalized criteria for a shared definition of poor mobilizer in order to facilitate randomized clinical trials and study comparison focusing on the efficacy of current mobilizing regimens. The availability of a standardized tool for poor mobilizer definition suggested us to retrospectively test GITMO criteria feasibility and applicability. Therefore we analyzed medical and laboratory records of adult patients affected by myeloma (MM) or lymphoma undergoing mobilization for autologous peripheral blood HSC collection from January 2010 to June 2011, at Servizio di Emotrasfusione, Istituto di Ematologia, Università Cattolica Del Sacro Cuore, Roma, UOC SIMT AO S. Camillo Forlanini Roma and SIMT Fondazione Policlinico Tor Vergata Roma. We collected data about 227 patients (134 male, 93 female) affected by MM (31.3%) NHL (58.6%) e HD (10.1%). Thirty-nine patients, 21 male and 18 female met proven poor mobilizer criteria definition resulting in a incidence of 17.2% (12.7% in MM, 21.8% in NHL and 4.3% in HD). Eleven patients, seven affected by lymphoma and four affected by myeloma, were defined predicted PM according to major criteria. Eight patients, seven affected by lymphoma and one affected by myeloma, were define predicted PM according to minor criteria. Sixteen out of 39 patients defined as poor mobilizer either according to major or minor criteria underwent collection procedures and eight (20.5%) achieved a cell dose ⩾2×10(6)/kg CD34(+) cells. GITMO criteria application was easy and resulted in poor mobilizer incidence comparable to current literature. Definitions of proven poor mobilizer and predicted poor mobilizer according to major criteria were very effective while minor criteria were less predictive. These results came from a retrospective analysis and therefore should be validated in future prospective trial. On the other hand these data could be

  14. Two criteria for evaluating risk prediction models.

    Science.gov (United States)

    Pfeiffer, R M; Gail, M H

    2011-09-01

    We propose and study two criteria to assess the usefulness of models that predict risk of disease incidence for screening and prevention, or the usefulness of prognostic models for management following disease diagnosis. The first criterion, the proportion of cases followed PCF (q), is the proportion of individuals who will develop disease who are included in the proportion q of individuals in the population at highest risk. The second criterion is the proportion needed to follow-up, PNF (p), namely the proportion of the general population at highest risk that one needs to follow in order that a proportion p of those destined to become cases will be followed. PCF (q) assesses the effectiveness of a program that follows 100q% of the population at highest risk. PNF (p) assess the feasibility of covering 100p% of cases by indicating how much of the population at highest risk must be followed. We show the relationship of those two criteria to the Lorenz curve and its inverse, and present distribution theory for estimates of PCF and PNF. We develop new methods, based on influence functions, for inference for a single risk model, and also for comparing the PCFs and PNFs of two risk models, both of which were evaluated in the same validation data.

  15. Nevada National Security Site Waste Acceptance Criteria

    Energy Technology Data Exchange (ETDEWEB)

    NSTec Environmental Management

    2012-02-28

    This document establishes the U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Site Office (NNSA/NSO), Nevada National Security Site Waste Acceptance Criteria (NNSSWAC). The NNSSWAC provides the requirements, terms, and conditions under which the Nevada National Security Site (NNSS) will accept DOE non-radioactive classified waste, DOE non-radioactive hazardous classified waste, DOE low-level radioactive waste (LLW), DOE mixed low-level waste (MLLW), and U.S. Department of Defense (DOD) classified waste for permanent disposal. Classified waste is the only waste accepted for disposal that may be non-radioactive and will be required to meet the waste acceptance criteria for radioactive waste as specified in this document. The NNSA/NSO and support contractors are available to assist you in understanding or interpreting this document. For assistance, please call the NNSA/NSO Waste Management Project (WMP) at (702) 295-7063, and your call will be directed to the appropriate contact.

  16. Nevada National Security Site Waste Acceptance Criteria

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2013-06-01

    This document establishes the U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Field Office (NNSA/NFO), Nevada National Security Site Waste Acceptance Criteria (NNSSWAC). The NNSSWAC provides the requirements, terms, and conditions under which the Nevada National Security Site (NNSS) will accept the following: • DOE hazardous and non-hazardous non-radioactive classified waste • DOE low-level radioactive waste (LLW) • DOE mixed low-level waste (MLLW) • U.S. Department of Defense (DOD) classified waste The LLW and MLLW listed above may also be classified waste. Classified waste is the only waste accepted for disposal that may be non-radioactive and shall be required to meet the waste acceptance criteria for radioactive waste as specified in this document. Classified waste may be sent to the NNSS as classified matter. Section 3.1.18 provides the requirements that must be met for permanent burial of classified matter. The NNSA/NFO and support contractors are available to assist the generator in understanding or interpreting this document. For assistance, please call the NNSA/NFO Environmental Management Operations (EMO) at (702) 295-7063, and the call will be directed to the appropriate contact.

  17. Spatial Development Potential Considering Conservation Planning Criteria

    Directory of Open Access Journals (Sweden)

    Dora Tomić

    2011-06-01

    Full Text Available The paper focuses on the issues of possible differences in the decision considering spatial allocation of land use and its potential and optimized allocation that derives from suitability modeling. The researched area was Žumberak- Samoborsko gorje Nature Park, one of the youngest Croatian nature parks. As such, it should have a physical plan of the special features areas, in order to know its potential and limitations. There is no such plan yet, so protection measures and development is relinquished to cities and municipalities, within whose territory the Park is situated. One of the municipalities is Ozalj, and it is used in the paper as an example for the analysis of physical planning approach for Žumberak- Samoborsko gorje Nature Park. By the survey of Physical plan of Ozalj municipality, a random selection was used to choose one activity that was planned in the area and for that activity dual spatial analysis was created. It included spatial attractiveness and vulnerability analysis. The results of the analysis have shown whether, in addition to spatial attractiveness criteria, spatial vulnerability criteria was taken into consideration when deciding on the location for the winter sports center. The analysis has also shown whether the Physical plan was in favor of the municipality development or was the fact that it is a Nature Park, designed as the protected area of natural and cultural values, also considered relevant.

  18. Steam generator tube integrity flaw acceptance criteria

    Energy Technology Data Exchange (ETDEWEB)

    Cochet, B. [FRAMATOME, Paris la Defense (France)

    1997-02-01

    The author discusses the establishment of a flaw acceptance criteria with respect to flaws in steam generator tubing. The problem is complicated because different countries take different approaches to the problem. The objectives in general are grouped in three broad areas: to avoid the unscheduled shutdown of the reactor during normal operation; to avoid tube bursts; to avoid excessive leak rates in the event of an accidental overpressure event. For each degradation mechanism in the tubes it is necessary to know answers to an array of questions, including: how well does NDT testing perform against this problem; how rapidly does such degradation develop; how well is this degradation mechanism understood. Based on the above information it is then possible to come up with a policy to look at flaw acceptance. Part of this criteria is a schedule for the frequency of in-service inspection and also a policy for when to plug flawed tubes. The author goes into a broad discussion of each of these points in his paper.

  19. Criteria Considerations for Establishment of Hems Operations

    Directory of Open Access Journals (Sweden)

    Borivoj Galović

    2007-05-01

    Full Text Available The importance of the "golden hour"; for optimal efficiencyof helicopter operations in emergency medical service (HEMSto meet the "golden hour" requirement the unconditional requirementis to establish a net of operational units to cover theentire area of the Republic of Croatia, capable to operate withinwide integrated area (international services. It is additionalback-up, not a competition to road and sea EMS vehicles. Therequired standards; HEMS operation, following complementarytraffic policy, i. e. complementary policy in line of trafficsystem integration within wider region, with reference to standards,must entirely comply with globally accepted standards.Republic of Croatia 's obvious objectives are traffic integrationinto EU (European Union traffic system. Cost analyses; It isstressed that coherent traffic policy can by certain instrumentsreduce traffic assigned external cost in national budget. Significanttraffic external cost includes cost of traffic accidents, environmentimpacts and traffic jams, and could be reduced byestablishmentof multi-purpose helicopter operations. SWOTanalyses should be made as for any other strategy or project.Technical-technological criteria and other considerations;Considering technical-technological criteria for relief of criticalsituations in traffic, it is obvious that one helicopter type cannotcomply to all multi-purpose requirements that traffic sets beforeus - EMS on open roads, sea, mountains and urban trafficcongested area, and search and rescue operations. However,common factor for all types is compliance to global standardsand regulations. In the paper, some examples of HEMS operationsin the EU States are mentioned.

  20. [Clinical and immunological criteria of burn sepsis].

    Science.gov (United States)

    Shlyk, I V; Pivovarova, L P; Krylov, K M; Filippova, O V; Il'ina, V A; Krylov, P K

    2005-01-01

    A hundred and twenty-nine victims aged 16 to 60 years who had skin burns in the area of 15 to 60% of the body surface without severe concomitant somatic disease (SAPS less than 9 scores). The clinical symptoms of a systemic inflammatory response (SIR) and the signs of wound infection were recorded in all the examinees. The victims underwent a comprehensive clinical and laboratory examination, 55 of them were immunologically studied over time (on admission, on days 3 and 10). To reveal the predictive clinical and immunological criteria for sepsis, the examinees were divided into 3 groups. Group 1 comprised 33 burnt persons who were observed to have the symptoms of SIR and the signs of burn wound infections without impaired function of organs and systems. Group 2 included 46 victims with severe sepsis and a good outcome of burn disease. Group 3 consisted of 50 patients who had died from severe sepsis. Analysis of the results of the study has indicated that the count of formed blood elements by calculating the leukocytic intoxication index, the estimation of the level of lysosomal cation proteins in the neutrophilic granulocytes, the detection of populations of T helper cells, cytotoxic lymphocytes, as well as histomorphological and bacteriological findings are early and valid criteria for the development of infectious complications. Their use for the diagnosis and prediction of sepsis permits initiation of its treatment at early stages, without awaiting the appearance of the signs of a septic process.

  1. Microbiological criteria for good manufacturing practice (GMP)

    Energy Technology Data Exchange (ETDEWEB)

    Farkas, J. (Inst. of Preservation and Livestock Products Technology, Univ. of Horticulture and Food Industry, Budapest (Hungary)); Zukal, E. (Inst. of Preservation and Livestock Products Technology, Univ. of Horticulture and Food Industry, Budapest (Hungary))

    1992-01-01

    Good manufacturing practice (GMP) consist of an effective manufacturing operation and an effective application of food control. GMP is best supported by the Hazard Analysis Critical Control Point system (HACCP) of the preventive quality assurance, which requires that food irradiation as any food processing technology should be used only with foods of an acceptable quality and adequate handling and storage procedures should precede and follow the processing. The paper concentrates on the first element of the HACCP system for an irradiation plant: the incoming product control, i.e. whether GMP of foods to be irradiated can be assessed by establishing microbiological criteria for their previous good manufacturing practice. In this regard, it summarizes considerations and findings of a ''Consultation on Microbiological Criteria for Foods to be Further Processed Including by Irradiation'' held in 1989 by the International Consultative Group on Food irradiation at the Headquarters of the World Health Organization, Geneva. Difficulties in establishing reference values and defining good manufacturing practices will be pointed out. (orig.)

  2. Neuropsychiatric lupus: classification criteria in neuroimaging studies.

    Science.gov (United States)

    Netto, Tania M; Zimmermann, Nicolle; Rueda-Lopes, Fernanda; Bizzo, Bernardo C; Fonseca, Rochele P; Gasparetto, Emerson L

    2013-05-01

    This systematic review described the criteria and main evaluations methods procedures used to classify neuropsychiatric systemic lupus erythematosus (NPSLE) patients. Also, within the evaluations methods, this review aimed to identify the main contributions of neuropsychological measurements in neuroimaging studies. A search was conducted in PubMed, EMBASE and SCOPUS databases with the terms related to neuropsychiatric syndromes, systemic lupus erythematosus, and neuroimaging techniques. Sixty-six abstracts were found; only 20 were completely analyzed and included. Results indicated that the 1999 American College of Rheumatology (ACR) criteria is the most used to classify NPSLE samples together with laboratorial, cognitive, neurological and psychiatric assessment procedures. However, the recommended ACR assessment procedures to classify NPSLE patients are being used incompletely, especially the neuropsychological batteries. Neuropsychological instruments and neuroimaging techniques have been used mostly to characterize NPSLE samples, instead of contributing to their classifications. The most described syndromes in neuroimaging studies have been seizure/cerebrovascular disease followed by cognitive dysfunctions as well as headache disorder.

  3. The DSM-5: Classification and criteria changes.

    Science.gov (United States)

    Regier, Darrel A; Kuhl, Emily A; Kupfer, David J

    2013-06-01

    The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) marks the first significant revision of the publication since the DSM-IV in 1994. Changes to the DSM were largely informed by advancements in neuroscience, clinical and public health need, and identified problems with the classification system and criteria put forth in the DSM-IV. Much of the decision-making was also driven by a desire to ensure better alignment with the International Classification of Diseases and its upcoming 11th edition (ICD-11). In this paper, we describe select revisions in the DSM-5, with an emphasis on changes projected to have the greatest clinical impact and those that demonstrate efforts to enhance international compatibility, including integration of cultural context with diagnostic criteria and changes that facilitate DSM-ICD harmonization. It is anticipated that this collaborative spirit between the American Psychiatric Association (APA) and the World Health Organization (WHO) will continue as the DSM-5 is updated further, bringing the field of psychiatry even closer to a singular, cohesive nosology.

  4. University Ranking Systems; Criteria and Critiques

    Directory of Open Access Journals (Sweden)

    Yavuz SAKA

    2011-01-01

    Full Text Available The purpose of this paper is to explore international university ranking systems. As a compilation study this paper provides specific criteria that each ranking system uses and main critiques regarding these ranking systems. Since there are many ranking systems in this area of research, this study focused on only most cited and referred ranking systems. As there is no consensus in terms of the criteria that these systems use, this paper has no intention of identifying the best ranking system based on a comparative analysis. Rather, this paper may inform relevant interest groups in higher education about the ranking systems and their decisive factors as universities attempt to place their names on the most known ranking systems. This study may provide brief but extensive information to Turkish Higher Education researchers and universities as they participate in Erasmus and Mevlana to open their doors to international higher education world. To become one of the top universities, this paper suggests that universities should know and understand the realities of international competitiveness in higher education and based on such understanding they can mold their physical, structural and academic futures toward achieving their visions and foundational missions.

  5. The DSM-5: Classification and criteria changes

    Science.gov (United States)

    Regier, Darrel A; Kuhl, Emily A; Kupfer, David J

    2013-01-01

    The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) marks the first significant revision of the publication since the DSM-IV in 1994. Changes to the DSM were largely informed by advancements in neuroscience, clinical and public health need, and identified problems with the classification system and criteria put forth in the DSM-IV. Much of the decision-making was also driven by a desire to ensure better alignment with the International Classification of Diseases and its upcoming 11th edition (ICD-11). In this paper, we describe select revisions in the DSM-5, with an emphasis on changes projected to have the greatest clinical impact and those that demonstrate efforts to enhance international compatibility, including integration of cultural context with diagnostic criteria and changes that facilitate DSM-ICD harmonization. It is anticipated that this collaborative spirit between the American Psychiatric Association (APA) and the World Health Organization (WHO) will continue as the DSM-5 is updated further, bringing the field of psychiatry even closer to a singular, cohesive nosology. PMID:23737408

  6. Construct Validity of the Pediatric Rome III Criteria

    National Research Council Canada - National Science Library

    Saps, Miguel; Nichols-Vinueza, Diana X; Mintjens, Stijn; Pusatcioglu, Cenk K; Velasco-Benítez, Carlos A

    2014-01-01

    .... There is little evidence of validity for the pediatric Rome III criteria. The construct validity of the criteria, an overarching term that incorporates other forms of validity, has never been assessed...

  7. Crew Transportation Technical Standards and Design Evaluation Criteria

    Science.gov (United States)

    Lueders, Kathryn L.; Thomas, Rayelle E. (Compiler)

    2015-01-01

    Crew Transportation Technical Standards and Design Evaluation Criteria contains descriptions of technical, safety, and crew health medical processes and specifications, and the criteria which will be used to evaluate the acceptability of the Commercial Providers' proposed processes and specifications.

  8. Criteria for sustainable livestock production: a proposal for implementation

    NARCIS (Netherlands)

    Wit, de J.; Oldenbroek, J.K.; Keulen, van H.; Zwart, D.

    1995-01-01

    After discussing some general problems in measuring sustainability, an identification of measurable criteria for the major agroecological problems is proposed, derived from explicit issues of unsustainability. The proposed criteria are briefly discussed. Factors which might influence the effect of i

  9. Computer programs: Mechanical and structural design criteria: A compilation

    Science.gov (United States)

    1973-01-01

    Computerized design criteria for turbomachinery and the constraints imposed by very high rotational fields are presented along with a variety of computerized design criteria of interest to structural designers.

  10. Information Theoretic Criteria for Observation-to-Observation Association

    Science.gov (United States)

    2014-09-01

    orbit determination (IOD) method as well as criteria from information theory . The two main criteria we use in this paper are mutual information and...problem by using an appropriate initial orbit determination (IOD) method as well as criteria from information theory . The two main criteria we use in...approaches as they more accurately capture degree of dependence between variables. This paper barely touches the tip of the iceberg , and its most

  11. Development of Clinical Rating Criteria for Tests of Lumbopelvic Stability

    Directory of Open Access Journals (Sweden)

    Margaret A. Perrott

    2012-01-01

    Objective. To develop rating criteria for three clinical tests of LPS. Design. Qualitative research: focus group. Method. A focus group of five expert physiotherapists used qualitative methods to develop rating criteria for the three clinical tests. Results. Detailed rating criteria were established for the three tests. Each key factor considered important for LPS had characteristics described that represented both good and poor LPS. Conclusion. This study established rating criteria that may be used to clinically assess LPS.

  12. Convergence in the EU related to the Maastricht criteria

    OpenAIRE

    Magdaléna DRASTICHOVÁ

    2013-01-01

    Regarding the entry into the euro area, the convergence of the EU economies can be monitored in several dimensions. One of them is the convergence represented by the Maastricht criteria, which are the only official conditions of joining the euro area for the EU countries. The aim of this paper is to detect the development of convergence related to these criteria in the EU and to draw mutual relations between the convergence criteria and the impact of compliance with these criteria...

  13. The diagnostic criteria of pityriasis rosea and Gianotti-Crosti syndrome - a protocol to establish diagnostic criteria of skin diseases.

    Science.gov (United States)

    Chuh, A; Zawar, V; Sciallis, G F; Lee, A

    2015-01-01

    We established and validated diagnostic criteria for pityriasis rosea and Gianotti-Crosti syndrome. In this paper, we compare and contrast both diagnostic criteria to formulate a protocol in establishing diagnostic criteria for other dermatological diseases. The diagnostic criteria are similar in employing clear dividing lines and conjunctions ('and/or') to assure high reliability. Both sets of criteria should be applicable for all ethnic groups. Spontaneous remission is not included, so diagnosis is not delayed while waiting for disease remission. Laboratory investigations are not enlisted, so that the criteria can be used in medical care systems in different parts of the world. The diagnostic criteria are different in that pathognomonic clinical manifestations exist for pityriasis rosea, such as the herald patch and the orientation of lesions along the lines of skin cleavages. These features, however, score low for sensitivity. These specific manifestations are not seen in Gianotti-Crosti syndrome. Such differences led to different categorisation of clinical features. Atypical variants are more common for pityriasis rosea. The diagnostic criteria for pityriasis rosea therefore do not include a list of differential diagnoses, while diagnostic criteria for Gianotti-Crosti syndrome do. Using this comparison, we constructed a protocol to establish diagnostic criteria for other skin diseases. We advocate the need to justify the establishment of diagnostic criteria, that multiple diagnostic criteria for the same disease should be avoided, that diagnostic criteria should be compatible with the disease classification if applicable, and that the scope should be well-delineated with regard to clinical variants. We outline the need for validation studies to assess the criteria-related validity, test-retest intra-clinician reliability, and inter-clinician reliability. We emphasise that the establishment of diagnostic criteria should not be a generic process. We also

  14. Comparison of outburst danger criteria of coal seams for acoustic spectral and instrumental forecast methods

    Science.gov (United States)

    Shadrin, A. V.; Bireva, Yu A.

    2016-10-01

    Outburst danger criteria for the two methods of current coal seam outburst forecast are considered: instrumental - by the initial outgassing rate and chippings outlet during test boreholes drilling, and geo-physical - by relation of high frequency and low frequency components of noise caused by cutting tool of operating equipment probing the face area taking into consideration the outburst criteria correction based on methane concentration at the face area and the coal strength. The conclusion is made on “adjustment” possibility of acoustic spectral forecast method criterion amended by control of methane concentration at the coal face and the coal strength taken from the instrumental method forecast results.

  15. 75 FR 41577 - VBA/VHA Musculoskeletal Forum: Improving VA's Disability Evaluation Criteria

    Science.gov (United States)

    2010-07-16

    ...The Department of Veterans Affairs (VA) will hold the Veterans Benefits Administration (VBA)/Veterans Health Administration (VHA) Musculoskeletal Forum: Improving VA's Disability Criteria to capture public comment and current medical science information from presentations made by subject matter experts. VA plans to use this information to update the sections of VA's Schedule for Rating Disabilities (VASRD) that pertain to diseases and injuries of the musculoskeletal system. See 38 CFR 4.40-4.73. Specifically, diagnostic code descriptors and evaluation criteria will be discussed. Contingent upon available capacity and time, individuals wishing to make oral statements will be accommodated on a first-come, first-served basis.

  16. Incorporating User Performance Criteria into Building Sustainability Rating Tools (BSRTs for Buildings in Operation

    Directory of Open Access Journals (Sweden)

    George Baird

    2009-11-01

    Full Text Available Current Building Sustainability Rating Tools (BSRTs are concerned mainly with the technical features of new designs. The author argues for the inclusion of user performance criteria in BSRTs for buildings in operation. The case is based on insights gained from surveys of users of sustainable buildings worldwide, and a review of the pioneering NABERS protocol. The paper advocates the establishment of a set of user performance criteria for existing buildings, as a key ingredient in making progress towards a truly sustainable building stock as buildings that perform poorly from the users‘ point of view are unlikely to ever be sustainable.

  17. Agreement between the 2009 STOPP Criteria and the 2003 Beers Criteria at the time of hospital admission

    Directory of Open Access Journals (Sweden)

    María Muñoz García

    2016-12-01

    Full Text Available Potentially inappropriate prescription in elderly patients can be evaluated by different methods. The STOPP Criteria and Beers Criteria stand out among the explicit criteria most widely used. Objective: The main objective of this study is to identify the agreement in the detection of potentially inappropriate prescribing between the STOPP criteria and the Beers Criteria, in elderly patients assessed at the time of hospital admission. Method: An observational retrospective study was designed in order to estimate the prevalence of potentially inappropriate prescription in the habitual treatment before admission, and to compare the agreement in detection capability between the 2003 Beers Criteria and the 2009 STOPP Criteria, in >70-yearold patients with an emergency hospital admission. There was also a specific analysis of the prescription of first-generation antihistamines, tricyclic antidepressants, benzodiazepines, and selective serotonin reuptake inhibitors, which are considered drugs with irregular management and potential toxicity. Results: The total prevalence of patients with a potentially inappropriate prescription was 23.8% using the Beers Criteria and 33.3% using the STOPP Criteria. There was a low level of agreement between both questionnaires. First-generation antihistamines (Beers and pharmacological duplication (STOPP J were the criteria most frequently found. There were differences in the prevalence of potentially inappropriate prescription in the four pharmacological groups selected; and in all cases, detection by Beers Criteria was superior. Conclusion: There is no agreement between the STOPP Criteria and the Beers Criteria regarding the detection of patients with potentially inappropriate prescribing at the time of hospital admission.

  18. 47 CFR 22.567 - Technical channel assignment criteria.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Technical channel assignment criteria. 22.567... Technical channel assignment criteria. The rules in this section establish technical assignment criteria for... channel assignments to be made in a manner such that reception by public mobile receivers of signals from...

  19. MRI criteria for MS in patients with clinically isolated syndromes

    DEFF Research Database (Denmark)

    Montalban, X.; Tintore, M.; Swanton, J.;

    2010-01-01

    In recent years, criteria for the diagnosis of multiple sclerosis (MS) have changed, mainly due to the incorporation of new MRI criteria. While the new criteria are a logical step forward, they are complex and-not surprisingly-a good working knowledge of them is not always evident among neurologi...

  20. Refining the classification criteria for primary Sjogren syndrome

    NARCIS (Netherlands)

    Vissink, Arjan; Bootsma, Hendrika

    2017-01-01

    The 2016 ACR-EULAR classification criteria for primary Sjogren syndrome, which are intended to facilitate uniform classification of patients for enrolment in clinical studies, combine features of previous criteria sets. These new criteria are a step in the right direction, but further refinement wou

  1. 49 CFR 37.131 - Service criteria for complementary paratransit.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Service criteria for complementary paratransit. 37... FOR INDIVIDUALS WITH DISABILITIES (ADA) Paratransit as a Complement to Fixed Route Service § 37.131 Service criteria for complementary paratransit. The following service criteria apply to...

  2. Exploring the Proposed DSM-5 Criteria in a Clinical Sample

    Science.gov (United States)

    Taheri, Azin; Perry, Adrienne

    2012-01-01

    The proposed DSM-5 criteria for Autism Spectrum Disorder (ASD) depart substantially from the previous DSM-IV criteria. In this file review study of 131 children aged 2-12, previously diagnosed with either Autistic Disorder or Pervasive Developmental Disorder-Not Otherwise Specified (PDD-NOS), 63% met the new DSM-5 ASD criteria, including 81%…

  3. User-Centric Multi-Criteria Information Retrieval

    Science.gov (United States)

    Wolfe, Shawn R.; Zhang, Yi

    2009-01-01

    Information retrieval models usually represent content only, and not other considerations, such as authority, cost, and recency. How could multiple criteria be utilized in information retrieval, and how would it affect the results? In our experiments, using multiple user-centric criteria always produced better results than a single criteria.

  4. Evaluation Criteria for the Educational Web-Information System

    Science.gov (United States)

    Seok, Soonhwa; Meyen, Edward; Poggio, John C.; Semon, Sarah; Tillberg-Webb, Heather

    2008-01-01

    This article addresses how evaluation criteria improve educational Web-information system design, and the tangible and intangible benefits of using evaluation criteria, when implemented in an educational Web-information system design. The evaluation criteria were developed by the authors through a content validation study applicable to…

  5. Analysis criteria market veterinary preparations which touch commodity segmentation

    OpenAIRE

    OLENICH I.; KHARIV I.; GYTUJ B.

    2012-01-01

    It is well-proven that the criteria of market of veterinary preparations segmentation must represent the features of this market. At researches, in every case, depending on the put purpose, market segmentation can be conducted by system of the most complete scope of criteria, or after one or by a few criteria.

  6. Evaluation Criteria for the Educational Web-Information System

    Science.gov (United States)

    Seok, Soonhwa; Meyen, Edward; Poggio, John C.; Semon, Sarah; Tillberg-Webb, Heather

    2008-01-01

    This article addresses how evaluation criteria improve educational Web-information system design, and the tangible and intangible benefits of using evaluation criteria, when implemented in an educational Web-information system design. The evaluation criteria were developed by the authors through a content validation study applicable to…

  7. 40 CFR 132.3 - Adoption of criteria.

    Science.gov (United States)

    2010-07-01

    ... with: (a) The acute water quality criteria for protection of aquatic life in Table 1 of this part, or a... chronic water quality criteria for protection of aquatic life in Table 2 of this part, or a site-specific... Tribes shall adopt numeric water quality criteria for the purposes of section 303(c) of the Clean Water...

  8. 77 FR 71191 - 2012 Recreational Water Quality Criteria

    Science.gov (United States)

    2012-11-29

    ... authorized Tribes are to adopt water quality criteria to protect designated uses (e.g., aquatic life... AGENCY 2012 Recreational Water Quality Criteria AGENCY: Environmental Protection Agency (EPA). ACTION: Notice of availability of the 2012 Recreational Water Quality Criteria. SUMMARY: Pursuant to section 304...

  9. Structural acceptance criteria Remote Handling Building Tritium Extraction Facility

    Energy Technology Data Exchange (ETDEWEB)

    Mertz, G.

    1999-12-16

    This structural acceptance criteria contains the requirements for the structural analysis and design of the Remote Handling Building (RHB) in the Tritium Extraction Facility (TEF). The purpose of this acceptance criteria is to identify the specific criteria and methods that will ensure a structurally robust building that will safely perform its intended function and comply with the applicable Department of Energy (DOE) structural requirements.

  10. 19 CFR 143.43 - RLF eligibility criteria.

    Science.gov (United States)

    2010-04-01

    ... TREASURY (CONTINUED) SPECIAL ENTRY PROCEDURES Remote Location Filing § 143.43 RLF eligibility criteria. (a) Automation criteria. To be eligible for RLF, a licensed customs broker or importer of record must be: (1... 19 Customs Duties 2 2010-04-01 2010-04-01 false RLF eligibility criteria. 143.43 Section...

  11. Mahalanobis Taguchi system based criteria selection tool for agriculture crops

    Indian Academy of Sciences (India)

    N DEEPA; K GANESAN

    2016-12-01

    Agriculture crop selection cannot be formulated from one criterion but from multiple criteria. A list of criteria for crop selection was identified through literature survey and agricultural experts. The identified criteria were grouped into seven main criteria namely, soil, water, season, input, support, facilities and threats. In this paper, Mahalanobis Taguchi system based tool was developed for identification of useful set of criteriawhich is a subset of the original criteria, for taking decision on crop selection in a given agriculture land. The combination of Mahalanobis distance and Taguchi method is used for identification of important criteria. Matlab software was used to develop the tool. After entering the values for each main criteria in the tool, it will process the value and identify the useful sub-criteria under each main criteria for selecting the suitable crop in a givenagriculture land. Instead of considering all criteria, one can use these useful set of criteria under each main criteria for taking decision on crop selection in agriculture.

  12. Exploring the Proposed DSM-5 Criteria in a Clinical Sample

    Science.gov (United States)

    Taheri, Azin; Perry, Adrienne

    2012-01-01

    The proposed DSM-5 criteria for Autism Spectrum Disorder (ASD) depart substantially from the previous DSM-IV criteria. In this file review study of 131 children aged 2-12, previously diagnosed with either Autistic Disorder or Pervasive Developmental Disorder-Not Otherwise Specified (PDD-NOS), 63% met the new DSM-5 ASD criteria, including 81%…

  13. Validation of the 2010 ACR/EULAR classification criteria for rheumatoid arthritis: slight improvement over the 1987 ACR criteria.

    NARCIS (Netherlands)

    Britsemmer, K.; Ursum, J.; Gerritsen, M.; Tuyl, L. van; Schaardenburg, D. van

    2011-01-01

    Abstract: Background Recently, an American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) collaboration developed new classification criteria for rheumatoid arthritis (RA). Objective:To evaluate the diagnostic and discriminative ability of these new criteria compared with

  14. Validation of the 2010 ACR/EULAR classification criteria for rheumatoid arthritis: slight improvement over the 1987 ACR criteria.

    NARCIS (Netherlands)

    Britsemmer, K.; Ursum, J.; Gerritsen, M.; Tuyl, L. van; Schaardenburg, D. van

    2011-01-01

    Abstract: Background Recently, an American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) collaboration developed new classification criteria for rheumatoid arthritis (RA). Objective:To evaluate the diagnostic and discriminative ability of these new criteria compared with t

  15. GIS modelling for new landfill sites: critical review of employed criteria and methods of selection criteria

    Science.gov (United States)

    Abujayyab, Sohaib K. M.; Ahamad, Mohd Sanusi S.; Shukri Yahya, Ahmad; Bashir, Mohammed J. K.; Aziz, Hamidi Abdul

    2016-06-01

    Policy makers and the public are increasingly concerned with the determination of landfill-siting input criteria (DLSIC) in landfill modelling procedures as an area of research. Thus, its procedures are complicated and decision makers are increasingly pressured. These procedures can be considerably develop in order to reduce the negative effect of landfill locations on the environment, economy, and society. In this review article, literature related to the developments of 64 models and their procedures in the past 18 years (from 1997 to 2014) were comprehensively survey. DLSIC are determined through a conventional method. The frequency of criterion usage reflects the limitation of Conventional method for DLSIC. Moreover, some of these studies utilize unrelated criteria that are time-consuming, costly, arduous, and fruitless. Potential improvement in Geographic information systems GIS modelling parameter for landfill sites via utilizing multivariate analysis (MVA) instead of Conventional method (CM) through for DLSIC (e.g., Input variables, Accuracy, objectivity, reliability of criteria, time consumption, cost and comprehensiveness) were emphasize. It can be conclude that expenses can be reduce by implementing MVA in DLSIC for landfill modelling using geographic information systems (GIS) based on the corresponding significant level. Moreover, the determined criteria can be accurate, satisfying, sufficient, and free of bias from experts and human error.

  16. Stability Criteria of 3D Inviscid Shears

    CERN Document Server

    Li, Y Charles

    2009-01-01

    The classical plane Couette flow, plane Poiseuille flow, and pipe Poiseuille flow share some universal 3D steady coherent structure in the form of "streak-roll-critical layer". As the Reynolds number approaches infinity, the steady coherent structure approaches a 3D limiting shear of the form ($U(y,z), 0, 0$) in velocity variables. All such 3D shears are steady states of the 3D Euler equations. This raises the importance of investigating the stability of such inviscid 3D shears in contrast to the classical Rayleigh theory of inviscid 2D shears. Several general criteria of stability for such inviscid 3D shears are derived. In the Appendix, an argument is given to show that a 2D limiting shear can only be the classical laminar shear.

  17. COMBINED DAMAGE FRACTURE CRITERIA FOR PIEZOELECTRIC CERAMICS

    Institute of Scientific and Technical Information of China (English)

    Yang Xinhua; Chen Chuanyao; Hu Yuantai; Wang Cheng

    2005-01-01

    Mechanical and electrical damages are introduced to study the fracture mechanics of piezoelectric ceramics in this paper. Two kinds of piezoelectric fracture criteria are established using the method of least squares combined with a damage analysis of the well-known piezoelectric fracture experiments of Park and Sun's. One is based on a linear combination of the mechanical and electrical damages and the other on their nonlinear combination. When the combined damage D is up to its critical value Dc, piezoelectric fracture occurs. It is found from the qualitative comparison of the numerical results with the experimental data that the nonlinearly combined damage fracture criterion can give a better prediction of piezoelectric fracture. And it is concluded from the nonlinearly combined damage fracture criterion that a negative electric field impedes fracture whereas the effect of a positive electric field on fracture depends on its magnitude.

  18. EU Enlargement between Economic and Political Criteria

    Directory of Open Access Journals (Sweden)

    Romeo-Victor Ionescu

    2013-05-01

    Full Text Available The paper answers at two important questions: Is the EU able to support new adhering processes? and Is the Euro area able to enlarge in 2014? The comparative analysis in the paper covers four economic competitors: EU, USA, China and Japan, and is based on GDP growth rate, unemployment and inflation rates. The second part of the paper deals with an economic forecast during 2015-2016, focused on EU27, Euro area, Croatia and Latvia, in order to discuss the effects of the adhering to EU and Euro area. The results of the two-level analysis are supported by pertinent diagrams and annexes. The analysis uses a neutral statistical database – Eurostat – and dedicated forecast software. The main conclusion of the paper is that the adhering processes from 2013 and 2014 are based on economic and political criteria.

  19. ECODESIGN CRITERIA FOR COMPOSITE MATERIALS AND PRODUCTS

    Directory of Open Access Journals (Sweden)

    B. Attaf

    2015-07-01

    Full Text Available According to sustainable development principles, the design of a composite product must be in compliance with the new regulations and standards in terms of Health protection (H and Environmental preservation (E besides Quality assurance (Q. With this argument as an objective, our contribution aims to innovate and develop new methodologies providing sustainable design of new generation of composite products through the consideration of the three balanced key aspects: H, E and Q. To achieve these requirements, we have defined and developed new criteria in the form of eco-coefficients, which can later on be implemented into mechanical characterization tests, in advanced composite formulations and associated constitutive equations. They can also be integrated into future finite-element computer programs to assess and improve the performance of the H-E-Q interrelated function.

  20. ECODESIGN CRITERIA FOR COMPOSITE MATERIALS AND PRODUCTS

    Directory of Open Access Journals (Sweden)

    B. Attaf

    2013-06-01

    Full Text Available According to sustainable development principles, the design of a composite product must be in compliance with the new regulations and standards in terms of Health protection (H and Environmental preservation (E besides Quality assurance (Q. With this argument as an objective, our contribution aims to innovate and develop new methodologies providing sustainable design of new generation of composite products through the consideration of the three balanced key aspects: H, E and Q. To achieve these requirements, we have defined and developed new criteria in the form of eco-coefficients, which can later on be implemented into mechanical characterization tests, in advanced composite formulations and associated constitutive equations. They can also be integrated into future finite-element computer programs to assess and improve the performance of the H-E-Q interrelated function.

  1. Information criteria for astrophysical model selection

    CERN Document Server

    Liddle, A R

    2007-01-01

    Model selection is the problem of distinguishing competing models, perhaps featuring different numbers of parameters. The statistics literature contains two distinct sets of tools, those based on information theory such as the Akaike Information Criterion (AIC), and those on Bayesian inference such as the Bayesian evidence and Bayesian Information Criterion (BIC). The Deviance Information Criterion combines ideas from both heritages; it is readily computed from Monte Carlo posterior samples and, unlike the AIC and BIC, allows for parameter degeneracy. I describe the properties of the information criteria, and as an example compute them from WMAP3 data for several cosmological models. I find that at present the information theory and Bayesian approaches give significantly different conclusions from that data.

  2. A review of macroscopic ductile failure criteria.

    Energy Technology Data Exchange (ETDEWEB)

    Corona, Edmundo; Reedlunn, Benjamin

    2013-09-01

    The objective of this work was to describe several of the ductile failure criteria com- monly used to solve practical problems. The following failure models were considered: equivalent plastic strain, equivalent plastic strain in tension, maximum shear, Mohr- Coulomb, Wellman's tearing parameter, Johnson-Cook and BCJ MEM. The document presents the main characteristics of each failure model as well as sample failure predic- tions for simple proportional loading stress histories in three dimensions and in plane stress. Plasticity calculations prior to failure were conducted with a simple, linear hardening, J2 plasticity model. The resulting failure envelopes were plotted in prin- cipal stress space and plastic strain space, where the dependence on stress triaxiality and Lode angle are clearly visible. This information may help analysts select a ductile fracture model for a practical problem and help interpret analysis results.

  3. Location selection criteria for supplementary motorway facilities

    Directory of Open Access Journals (Sweden)

    Malobabić Radomir

    2002-01-01

    Full Text Available Supplementary contents along motorways are rather important facilities for a safe and secure functioning of a substantial part of the road transport system. In the paper, it has been stressed that our practice has not dealt with this problem satisfactorily throughout the motorways design process and especially in the realization phase. Therefore, the solving of this major issue ought to be approached systematically and planning oriented so as to achieve an optimal effect of supplementary contents in the motorways’ exploitation. The role of these facilities is multifold. Some relate to a safer road functioning and some enable a more comfortable and secure traveling. To make them work as a system it is indispensable to set up location selection criteria and rules for the complementary facilities Respecting the adequate rhythm and function dominance is exceptionally important as well as establishing the traffic safety and applying high ecological standards.

  4. Termination Criteria for Computerized Classification Testing

    Directory of Open Access Journals (Sweden)

    Nathan A. Thompson

    2011-02-01

    Full Text Available Computerized classification testing (CCT is an approach to designing tests with intelligent algorithms, similar to adaptive testing, but specifically designed for the purpose of classifying examinees into categories such as - pass- and - fail.- Like adaptive testing for point estimation of ability, the key component is the termination criterion, namely the algorithm that decides whether to classify the examinee and end the test or to continue and administer another item. This paper applies a newly suggested termination criterion, the generalized likelihood ratio (GLR, to CCT. It also explores the role of the indifference region in the specification of likelihood-ratio based termination criteria, comparing the GLR to the sequential probability ratio test. Results from simulation studies suggest that the GLR is always at least as efficient as existing methods.

  5. Selection criteria in organic cattle breeding

    Directory of Open Access Journals (Sweden)

    Savić Mila

    2014-01-01

    Full Text Available The central issue in process of organizing organic cattle breeding is the knowledge about specificities of this kind of production, good knowledge of breed characteristics (body composition, immune tolerance, expressed predisposition towards some diseases, production properties. Research centres, in collaboration with producers, have defined the essential features on which the selection programmes in organic cattle breeding are based on. Of the greatest importance for veterinary service is the fact that selection programmes in organic cattle breeding are in the first place based on giving priority to healthy animals, with strong immune system, good reproductive characteristics, which can be in production system for a long period. Additional important selective criteria is specific body resistance and adaptability of autochtonous breeds to environmental conditions. [Projekat Ministarstva nauke Republike Srbije, br. TP 31085

  6. Optimal design criteria - prediction vs. parameter estimation

    Science.gov (United States)

    Waldl, Helmut

    2014-05-01

    G-optimality is a popular design criterion for optimal prediction, it tries to minimize the kriging variance over the whole design region. A G-optimal design minimizes the maximum variance of all predicted values. If we use kriging methods for prediction it is self-evident to use the kriging variance as a measure of uncertainty for the estimates. Though the computation of the kriging variance and even more the computation of the empirical kriging variance is computationally very costly and finding the maximum kriging variance in high-dimensional regions can be time demanding such that we cannot really find the G-optimal design with nowadays available computer equipment in practice. We cannot always avoid this problem by using space-filling designs because small designs that minimize the empirical kriging variance are often non-space-filling. D-optimality is the design criterion related to parameter estimation. A D-optimal design maximizes the determinant of the information matrix of the estimates. D-optimality in terms of trend parameter estimation and D-optimality in terms of covariance parameter estimation yield basically different designs. The Pareto frontier of these two competing determinant criteria corresponds with designs that perform well under both criteria. Under certain conditions searching the G-optimal design on the above Pareto frontier yields almost as good results as searching the G-optimal design in the whole design region. In doing so the maximum of the empirical kriging variance has to be computed only a few times though. The method is demonstrated by means of a computer simulation experiment based on data provided by the Belgian institute Management Unit of the North Sea Mathematical Models (MUMM) that describe the evolution of inorganic and organic carbon and nutrients, phytoplankton, bacteria and zooplankton in the Southern Bight of the North Sea.

  7. Biochemical evidence supporting the Cortina criteria.

    Science.gov (United States)

    von Werder, K

    2005-01-01

    Whether acromegaly is inactive or active, respectively cured or not cured depends on the GH suppressibility and the basal IGF-I level. According to the Cortina criteria, GH suppression after oral ingestion of 75 g glucose to acromegaly. According to more recent publications, mortality, which is increased in active acromegaly, is normalized when GH and IGF-I levels have become normal as defined above. Morbidity, i.e. typical features of acromegaly like cardiac problems, carpal tunnel syndrome, carbohydrate intolerance, and excessive sweating may also improve though painful arthropathy, and coarse facial features usually remain unaltered even if the biochemistry has been completely normalized. Using more sensitive GH assays, a group of acromegalic patients was shown to have normal IGF-I levels after surgery, with post-glucose levels of GH 0.14 microg/l, which is the upper level of normal subjects and of a second group of successfully operated acromegalic patients. The latter group also had slightly lower IGF-I levels, though such levels were normal in both groups. Whether this may indicate that these patients who have higher GH levels after oral glucose measured with the more sensitive immunoradiometric assay (IRMA) will more likely develop recurrences remains to be demonstrated in a larger cohort. According to the criteria put forward in Cortina d'Ampezzo in February 1999, all patients who have post-glucose GH levels <1 microg/l and normal age-matched IGF-I levels have to be regarded as well controlled, i.e. sufficiently treated. Because of lack of evidence, there is at present no reason to change the consensus reached there.

  8. Criteria of enterprise marketing service base forming

    Directory of Open Access Journals (Sweden)

    O.A. Bilovodska

    2014-06-01

    Full Text Available The aim of the article. The aim of this article is to characterize basic personnel analysis methods, to propose own criteria which help to perform complex personnel evaluation by different departments. The results of the analysis. This article is based on the investigation of specialized literature regarding different personnel evaluation methods. Implementation of marketing concept in business requires corresponding service that examines marketing environment, analyzing market situation. It provides advice for successful existence in the market. Such functions must be performed by marketing department. Marketing department with other divisions forms an integrated process which aims to meet the market demand. Managers and leading specialists of marketing must satisfy the general requirements (competence, the ability to manage themselves, skills to solve problems, ability to train employees, etc.. Besides, they must satisfy a number of specific requirements that are specific. These requirements include: systematic knowledge, erudition, high analytical quality, communication, and diplomacy, ability to predict the situation and to make an effective decisions, ability to resolve conflicts. Personnel evaluation methods are divided into objective and subjective. Narrative techniques are dominated among objective. These methods can be used in various forms: as appliances of arbitrary description, structured descriptions, self-evaluation, and evaluation of defined objectives and in critical cases. Subjective methods usually cover comparative techniques that give relative knowledge: ranking, paired comparison and theoretical distribution. Complex methods combine several techniques that can’t be attributed only to the objective or only to the subjective methods. For example, sheet valuation, “model 360°”, personal portfolio. Authors suggested the following criteria of personnel evaluation: evaluation of marketing services; evaluation of individual

  9. Regulatory criteria: Legal or ecological thresholds?

    Energy Technology Data Exchange (ETDEWEB)

    Cook, J.M.; Skorupa, J.P.; Schwarzbach, S.E. [Fish and Wildlife Service, Sacramento, CA (United States)

    1994-12-31

    Selenium-laden irrigation drainwater has been identified as a significant threat to breeding waterfowl and shorebirds in terminal sink environments throughout the western United States. Due to historic wetland habitat losses, irrigation drainwater disposal ponds represent virtually all the available breeding habitat for waterbirds in the southern San Joaquin Valley of California. Egg selenium residues from birds breeding at these ponds have been monitored by the US Fish and Wildlife Service since 1987, and physiological risk thresholds for individual and population-level hatchability and teratogenesis have been determined from these studies. For Blacknecked stilt populations, egg selenium below 3 ppm may be considered a safe level, hatchability is significantly depressed at mean egg selenium concentrations above 8 ppm, and induction of teratogenesis is virtually certain at egg selenium levels above 18 ppm (p < 0.05). Egg samples collected in 1993 from these ponds showed concentrations as high as 160 ppm. Despite the high degree of statistical confidence in these effects thresholds, and the incidence of selenium-induced bird death and deformity at these ponds, regulation of evaporation ponds has been problematic. Existing civil statutes regarding water quality are dependent on risk-based criteria, but irrigation drainwater is exempted from these regulations. The only applicable law is the Migratory Bird Treaty Act, a criminal statute with no risk-based guidelines, and consequently no wildlife safety factors. The authors present data from the San Joaquin Valley in the context of these regulatory and legal limitations. Evaluation of acute and chronic models for ambient water quality indicate that this approach may not provide adequate protection for breeding birds. Based on the inadequacy of these models, the authors consider the development of regulatory criteria for egg selenium, a standard which is ecologically relevant.

  10. Conversion to dementia in mild cognitive impairment diagnosed with DSM-5 criteria and with Petersen's criteria.

    Science.gov (United States)

    Marcos, G; Santabárbara, J; Lopez-Anton, R; De-la-Cámara, C; Gracia-García, P; Lobo, E; Pírez, G; Menchón, J M; Palomo, T; Stephan, B C M; Brayne, C; Lobo, A

    2016-05-01

    In a background of revision of criteria for states of increased risk for progression to dementia, we compare the conversion rate to dementia and Alzheimer's disease (AD) of mild cognitive impairment (MCI) as diagnosed using DSM-5 (DSM-5-MCI) and Petersen's (P-MCI) criteria. A population representative cohort of 4057 dementia-free individuals 55+ years of age was followed up at 2.5 and 4.5 years in Zaragoza, Spain (ZARADEMP). Using the Geriatric Mental State- AGECAT for assessment, research psychiatrists diagnosed DSM-5-MCI and P-MCI following operationalized criteria. 'Conversion rate' (CR), 'annual conversion rate' (ACR), and incidence rate (IR) were calculated along with incidence rate ratio (IRR) to compare the performance of the intermediate cognitive definitions. At 4.5-year follow-up, in individuals aged 65+ years, ACRs for non-cases, P-MCI, and DSM-5-MCI were 0.8, 1.9 and 3.4, respectively, for global dementia. The IRRs were 2.9 and 5.3 for P-MCI and DSM5-MCI, respectively, being the non-cases the reference category. The corresponding values were slightly lower for AD. Conversion rate to dementia and AD was higher using DSM-5-MCI criteria than using Petersen's criteria. However, prediction of the construct still has some way to go, as most MCI individuals did not convert at 4.5-year follow-up. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  11. [Criteria of ineffectiveness of treatment with first-line therapy: how to use MRI results in decision making?].

    Science.gov (United States)

    Khachanova, N V; Davydovskaia, M V

    2015-01-01

    The importance of MRI stuides in the control over treatment efficacy in multiple sclerosis and appropriate recommendations on drug substitution during treatment are discussed. We suggest low, middle or high risk in respect to the efficacy of current treatment. Accordingly, drug substitution can be related with the low level of fears for all three criteria or the moderate level for any two criteria or the high level for any one criterion. Since MRI criteria are important, this model appears to be the most rational because the physician can make a decision about treatment escalation if the patient has ≥3 new T2-lesions or ≥3 contrast-enhanced T1-lesions.

  12. A search for new MRI criteria for dissemination in space in subjects with a clinically isolated syndrome

    DEFF Research Database (Denmark)

    Korteweg, T; Tintore, M; Uitdehaag, B M J;

    2009-01-01

    The International Panel on the Diagnosis of Multiple Sclerosis (MS) incorporated the Barkhof/Tintoré (B/T) magnetic resonance criteria into their diagnostic scheme to provide evidence of dissemination in space of central nervous system lesions, a prerequisite for diagnosing MS in patients who...... in a search for simpler and more sensitive criteria, while maintaining current specificity. The resulting models, all based on the presence of periventricular and deep white matter lesions, performed roughly in agreement with the B/T criteria, but were unable to provide higher diagnostic accuracy based...

  13. Diagnosis of spondyloarthritis: should we need new criteria?

    Directory of Open Access Journals (Sweden)

    I. Z. Gaidukova

    2015-01-01

    Full Text Available A large number of classification criteria for spondyloarthritis (SpA are simultaneously used in modern rheumatology in the almost complete absence of diagnostic criteria. This poses a number of problems, among which there are two most important ones: 1 the frequent use of classification criteria to make a diagnosis in real clinical practice; 2 the possibility of stating different nosological entities of SpA in one patient in the presence of the same clinical picture.Objective: to investigate the specific features of the diagnosis of SpA and the use of its classification criteria in clinical practice.Subjects and methods. The investigation enrolled 119 patients with the established diagnosis of ankylosing spondylitis (AS, psoriatic arthritis (PsA, undifferentiated axial or peripheral SpA. Whether their clinical picture complied with the modified New York criteria, the European Spondyloarthropathy Study Group (ESSG criteria, the Amor criteria, and the Assessment of Spondyloarthritis International Society (ASAS classification criteria for axial and peripheral SpA and whether the Russian version of the modified New York criteria complied with the Classification criteria of Psoriatic ARthritis (CASPAR were determined in the patients.Results. Sixty-three patients diagnosed with AS (M45, 44 with PsA (M07.0-07.3, 8 with undifferentiated SpA (M46.9, and 4 with nonradiographic axial SpA (M46.8 were followed up by attending physicians. The latter diagnosed AS in 10 patients who met the ASAS criteria for axial PsA but not the modified New York criteria. Twenty-one patients diagnosed as having PsA simultaneously met both the CASPAR criteria and the modified New York criteria, which could establish the diagnosis of AS in these cases. Eighty-one (68.0% out of the 119 patients met the Amor criteria; 98 (82.3% patients, the ESSG criteria; 91 (76.5%, the ASAS criteria for axial SpA; 18 (15.1%, the ASAS criteria for peripheral SpA; 76 (63.8%, the modified New York

  14. Flying qualities design criteria applicable to supersonic cruise aircraft

    Science.gov (United States)

    Chalk, C. R.

    1980-01-01

    A comprehensive set of flying qualities design criteria was prepared for use in the supersonic cruise research program. The framework for stating the design criteria is established and design criteria are included which address specific failures, approach to dangerous flight conditions, flight at high angle of attack, longitudinal and lateral directional stability and control, the primary flight control system, and secondary flight controls. Examples are given of lateral directional design criteria limiting lateral accelerations at the cockpit, time to roll through 30 deg of bank, and time delay in the pilot's command path. Flight test data from the Concorde certification program are used to substantiate a number of the proposed design criteria.

  15. Design Criteria for Achieving Acceptable Indoor Radon Concentration

    DEFF Research Database (Denmark)

    Rasmussen, Torben Valdbjørn

    2016-01-01

    Design criteria for achieving an acceptable indoor radon concentration are presented in this paper. The paper suggests three design criteria. These criteria have to be considered at the early stage of the building design phase to meet the latest recommendations from the World Health Organization...... from the ground, and the third criteria can dilute the indoor air. By combining these three criteria, the indoor radon concentration can be lowered achieving an acceptable level. In addition, a cheap and reliable method for measuring the radon concentration in the indoor air is described. The provision...

  16. New criteria of serviceability of aerodrome lighting equipment

    Directory of Open Access Journals (Sweden)

    С. Г. Ванецян

    2000-09-01

    Full Text Available Analyzed are the criteria of lighting equipment serviceability of various categories of aerodromes according to the materials of normative technical documentation of Ukrainian and Russian civil aviation and recommendations of ICAO. Proposed are new substantiated criteria of lighting equipment serviceability of various categories, under different atmospheric conditions which are based on recommendations and standards ICAO adapted to the conditions of new criteria in Ukraine. The advantages and correctness of new criteria are proved by calculation of reliability of imported modem lighting equipment by means of the worked out criteria

  17. The ethics of creating and responding to doubts about death criteria.

    Science.gov (United States)

    Dubois, James M

    2010-06-01

    Expressing doubts about death criteria can serve healthy purposes, but can also cause a number of harms, including decreased organ donation rates and distress for donor families and health care staff. This paper explores the various causes of doubts about death criteria-including religious beliefs, misinformation, mistrust, and intellectual questions-and recommends responses to each of these. Some recommended responses are relatively simple and noncontroversial, such as providing accurate information. However, other responses would require significant changes to the way we currently do business. Policymakers should establish minimum national standards for determining death to foster a trustworthy system; academics and publishers have a duty to publish only materials that substantially engage and advance the debate to minimize the harm caused by divided expert opinion; and opposition to the dead donor rule should be conceptually separated from doubts about death criteria.

  18. Diagnostic criteria for the characterization of quasireversible electron transfer reactions by cyclic square wave voltammetry.

    Science.gov (United States)

    Mann, Megan A; Helfrick, John C; Bottomley, Lawrence A

    2014-08-19

    Theory for cyclic square wave voltammetry of quasireversible electron transfer reactions is presented and experimentally verified. The impact of empirical parameters on the shape of the current-voltage curve is examined. From the trends, diagnostic criteria enabling the use of this waveform as a tool for mechanistic analysis of electrode reaction processes are presented. These criteria were experimentally confirmed using Eu(3+)/Eu(2+), a well-established quasireversible analyte. Using cyclic square wave voltammetry, both the electron transfer coefficient and rate were calculated for this analyte and found to be in excellent agreement with literature. When properly applied, these criteria will enable nonexperts in voltammetry to assign the electrode reaction mechanism and accurately measure electrode reaction kinetics.

  19. A mathematical analysis of the ABCD criteria for diagnosing malignant melanoma

    Science.gov (United States)

    Lee, Hyunju; Kwon, Kiwoon

    2017-03-01

    The medical community currently employs the ABCD (asymmetry, border irregularity, color variegation, and diameter of the lesion) criteria in the early diagnosis of a malignant melanoma. Although many image segmentation and classification methods are used to analyze the ABCD criteria, it is rare to see a study containing mathematical justification of the parameters that are used to quantify the ABCD criteria. In this paper, we suggest new parameters to assess asymmetry, border irregularity, and color variegation, and explain the mathematical meaning of the parameters. The suggested parameters are then tested with 24 skin samples. The parameters suggested for the 24 skin samples are displayed in three-dimensional coordinates and are compared to those presented in other studies (Ercal et al 1994 IEEE Trans. Biomed. Eng. 41 837-45, Cheerla and Frazier 2014 Int. J. Innovative Res. Sci., Eng. Technol. 3 9164-83) in terms of Pearson correlation coefficient and classification accuracy in determining the malignancy of the lesions.

  20. Multi-criteria decision making approaches for quality control of genome-wide association studies.

    Science.gov (United States)

    Malovini, Alberto; Rognoni, Carla; Puca, Annibale; Bellazzi, Riccardo

    2009-03-01

    Experimental errors in the genotyping phases of a Genome-Wide Association Study (GWAS) can lead to false positive findings and to spurious associations. An appropriate quality control phase could minimize the effects of this kind of errors. Several filtering criteria can be used to perform quality control. Currently, no formal methods have been proposed for taking into account at the same time these criteria and the experimenter's preferences. In this paper we propose two strategies for setting appropriate genotyping rate thresholds for GWAS quality control. These two approaches are based on the Multi-Criteria Decision Making theory. We have applied our method on a real dataset composed by 734 individuals affected by Arterial Hypertension (AH) and 486 nonagenarians without history of AH. The proposed strategies appear to deal with GWAS quality control in a sound way, as they lead to rationalize and make explicit the experimenter's choices thus providing more reproducible results.

  1. Module energy rating candidate reference days: Criteria and selection process

    Science.gov (United States)

    Myers, Daryl R.

    1999-03-01

    Presently the performance of flat-plate photovoltaic (PV) modules is based upon module power, open circuit voltage, short-circuit current, or peak power voltage and current with respect to fixed environmental conditions such as Standard Reporting Conditions, (SRC) or nominal operating cell temperature. These reporting conditions represent ideal conditions under which PV module performance (e.g., between manufacturers or technologies) may be compared. They result in overly optimistic expectations of performance by PV industry customers. A recommended practice for PV module energy-rating methodologies to relate PV module performance to real world conditions is under development. The methodologies will provide system designers and PV customers with an energy rating representative of real world conditions. The rating methodology reports energy production under 5 selected types of days representative of possible operational environments. The development and application of qualitative and quantitative criteria for identifying and selecting these representative days from the 30-year U.S. National Solar Radiation Data Base is described.

  2. Concepts and criteria for evaluating topsoil substitutes: The Texas experience

    Energy Technology Data Exchange (ETDEWEB)

    Askenasy, P.; Senkayi, A.L. [Railroad Commission of Texas, Austin, TX (United States); Joseph, W.L. [Office of Surface Mining, Alton, IL (United States)

    1997-12-31

    Presented in this paper are: (1) historical background, (2) Federal and State regulatory basis and authority, and (3) justification for selected criteria and parameters which are currently used to evaluate the quality of topsoil-substitute materials and postmine soils in Texas. The specific parameters and concepts discussed include (1) acid- and toxic-forming materials (AFM and TFM), (2) quantification procedures for AFM and TFM, (3) procedures used to identify topsoil substitutes that are {open_quotes}equal to or more suitable than{close_quotes} existing premine native soils, and (4) current interpretations of what is meant by {open_quotes}the best available material to support revegetation{close_quotes} of surface-mined areas. To support these interpretations, reference is made throughout the paper to relevant sections of the (1) Texas Coal Mining Regulations (TCMR), (2) Surface Mining Control and Reclamation Act (SMCRA), and (3) Federal regulations promulgated by the Office of Surface Mining (OSM) to implement SMCRA. The success of the Texas reclamation program, as indicated by the quality of the reclaimed soils is also discussed. This success is partly attributed to the rigorous application of the quantification concepts and parameters discussed in this paper.

  3. Diagnostic criteria and laboratory tests for disseminated intravascular coagulation.

    Science.gov (United States)

    Wada, Hideo; Matsumoto, Takeshi; Hatada, Tuyoshi

    2012-12-01

    Three diagnostic criteria for disseminated intravascular coagulation (DIC) have been established by the Japanese Ministry of Health, Labor and Welfare, the International Society on Thrombosis and Hemostasis (ISTH) and the Japanese Association for Acute Medicine. The diagnostic criteria involving global coagulation tests, such as the Japanese Ministry of Health, Labor and Welfare criteria and the ISTH overt diagnostic criteria, are first-generation DIC diagnostic criteria, those involving global coagulation tests and changes in these tests such as the Japanese Association for Acute Medicine criteria, are second-generation DIC diagnostic criteria, and those including non-overt DIC diagnostic criteria involving global coagulation tests, changes in these tests and hemostatic molecular markers will be the future (third-generation) DIC diagnostic criteria. There are no significant differences in the three diagnostic criteria with respect to predicting poor outcomes. Therefore, the third generation of diagnostic criteria including hemostatic molecular markers is expected to be established. Standardization and the determination of adequate cutoff values should be required for each laboratory test.

  4. Alternate tube plugging criteria for steam generator tubes

    Energy Technology Data Exchange (ETDEWEB)

    Cueto-Felgueroso, C.; Aparicio, C.B. [Tecnatom, S.A., Madrid (Spain)

    1997-02-01

    The tubing of the Steam Generators constitutes more than half of the reactor coolant pressure boundary. Specific requirements governing the maintenance of steam generator tubes integrity are set in Plant Technical Specifications and in Section XI of the ASME Boiler and Pressure Vessel Code. The operating experience of Steam Generator tubes of PWR plants has shown the existence of some types of degradatory processes. Every one of these has an specific cause and affects one or more zones of the tubes. In the case of Spanish Power Plants, and depending on the particular Plant considered, they should be mentioned the Primary Water Stress Corrosion Cracking (PWSCC) at the roll transition zone (RTZ), the Outside Diameter Stress Corrosion Cracking (ODSCC) at the Tube Support Plate (TSP) intersections and the fretting with the Anti-Vibration Bars (AVBs) or with the Support Plates in the preheater zone. The In-Service Inspections by Eddy Currents constitutes the standard method for assuring the SG tubes integrity and they permit the monitoring of the defects during the service life of the plant. When the degradation reaches a determined limit, called the plugging limit, the SG tube must be either repaired or retired from service by plugging. Customarily, the plugging limit is related to the depth of the defect. Such depth is typically 40% of the wall thickness of the tube and is applicable to any type of defect in the tube. In its origin, that limit was established for tubes thinned by wastage, which was the predominant degradation in the seventies. The application of this criterion for axial crack-like defects, as, for instance, those due to PWSCC in the roll transition zone, has lead to an excessive and unnecessary number of tubes being plugged. This has lead to the development of defect specific plugging criteria. Examples of the application of such criteria are discussed in the article.

  5. Semantics of Distinguishing Criteria: from Subjective to Intersubjective

    Directory of Open Access Journals (Sweden)

    Martin Takac, Jan Sefranek

    2012-10-01

    Full Text Available In this article we are aiming to build cognitive semantics over a first person perspective. Our goal is to specify meanings connected to cognitive agents, rooted in their experience and separable from language, covering a wide spectrum of cognitions ranging from living organisms (animals, pre-verbal children and adult humans to artificial agents and that the cognitive semantics covers a broad, continuous, spectrum of meanings.As regards the used method, the first person perspective enables a kind of grounding of meanings in cognitions. An ability of cognitive agents to distinguish is a starting point of our approach, distinguishing criteria and schemata are the basic semantic constructs.The resulting construction is based on a projection of the environment into a cluster of current percepts and a similarity function on percepts. Situation schemata, more sophisticated similarity functions, event schemata and distinguishing criteria are built over that basis. Inference rules and action rules are components of our semantics.An interesting property of the proposed semantics is that it makes possible coexistence of subjective and intersubjective meanings. Subjective (first person perspective meanings are primary, and we have shown the way from them to collectively accepted (third person perspective meanings via observable behaviour and feedback about success/failure of actions. An abductive reasoning is an important tool on that way. A construct of an instrument, which represents a measure for using intersubjective meanings, is introduced. The instrument serves as a tool for an inclusion of sophisticated meanings, e.g. of scientific constructs, into our framework.

  6. Estimating urban flood risk - uncertainty in design criteria

    Science.gov (United States)

    Newby, M.; Franks, S. W.; White, C. J.

    2015-06-01

    The design of urban stormwater infrastructure is generally performed assuming that climate is static. For engineering practitioners, stormwater infrastructure is designed using a peak flow method, such as the Rational Method as outlined in the Australian Rainfall and Runoff (AR&R) guidelines and estimates of design rainfall intensities. Changes to Australian rainfall intensity design criteria have been made through updated releases of the AR&R77, AR&R87 and the recent 2013 AR&R Intensity Frequency Distributions (IFDs). The primary focus of this study is to compare the three IFD sets from 51 locations Australia wide. Since the release of the AR&R77 IFDs, the duration and number of locations for rainfall data has increased and techniques for data analysis have changed. Updated terminology coinciding with the 2013 IFD release has also resulted in a practical change to the design rainfall. For example, infrastructure that is designed for a 1 : 5 year ARI correlates with an 18.13% AEP, however for practical purposes, hydraulic guidelines have been updated with the more intuitive 20% AEP. The evaluation of design rainfall variation across Australia has indicated that the changes are dependent upon location, recurrence interval and rainfall duration. The changes to design rainfall IFDs are due to the application of differing data analysis techniques, the length and number of data sets and the change in terminology from ARI to AEP. Such changes mean that developed infrastructure has been designed to a range of different design criteria indicating the likely inadequacy of earlier developments to the current estimates of flood risk. In many cases, the under-design of infrastructure is greater than the expected impact of increased rainfall intensity under climate change scenarios.

  7. Criteria for implementing interventions to reduce health inequalities in primary care settings in European regions.

    Science.gov (United States)

    Daponte, Antonio; Bernal, Mariola; Bolívar, Julia; Mateo, Inmaculada; Salmi, Louis-Rachid; Barsanti, Sara; Berghmans, Luc; Piznal, Ewelina; Bourgueil, Yann; Marquez, Soledad; González, Ingrid; Carriazo, Ana; Maros-Szabo, Zsuzsanna; Ménival, Solange

    2014-12-01

    The current social and political context is generating socio-economic inequalities between and within countries, causing and widening health inequalities. The development and implementation of interventions in primary health care (PHC) settings seem unavoidable. Attempts have been made to draw up adequate criteria to guide and evaluate interventions but none for the specific case of PHC. This methodological article aims to contribute to this field by developing and testing a set of criteria for guiding and evaluating real-life interventions to reduce health inequalities in PHC settings in European regions. A literature review, nominal group technique, survey and evaluation template were used to design and test a set of criteria. The questionnaire was answered by professionals in charge of 46 interventions carried out in 12 European countries, and collected detailed information about each intervention. Third-party experts scored the interventions using the set of evaluation criteria proposed. Nine criteria to guide and evaluate interventions were proposed: relevance, appropriateness, applicability, innovation, quality assurance, adequacy of resources, effectiveness in the process, effectiveness in results and mainstreaming. A working definition was drawn up for each one. These criteria were then used to evaluate the interventions identified. The set of criteria drawn up to guide the design, implementation and evaluation of interventions to reduce health inequalities in PHC will be a useful instrument to be applied to interventions under development for culturally, politically and socio-economically diverse PHC contexts throughout Europe. © The Author 2014. Published by Oxford University Press on behalf of the European Public Health Association. All rights reserved.

  8. Enhancing reuse of structured eligibility criteria and supporting their relaxation.

    Science.gov (United States)

    Milian, Krystyna; Hoekstra, Rinke; Bucur, Anca; Ten Teije, Annette; van Harmelen, Frank; Paulissen, John

    2015-08-01

    Patient recruitment is one of the most important barriers to successful completion of clinical trials and thus to obtaining evidence about new methods for prevention, diagnostics and treatment. The reason is that recruitment is effort consuming. It requires the identification of candidate patients for the trial (the population under study), and verifying for each patient whether the eligibility criteria are met. The work we describe in this paper aims to support the comparison of population under study in different trials, and the design of eligibility criteria for new trials. We do this by introducing structured eligibility criteria, that enhance reuse of criteria across trials. We developed a method that allows for automated structuring of criteria from text. Additionally, structured eligibility criteria allow us to propose suggestions for relaxation of criteria to remove potentially unnecessarily restrictive conditions. We thereby increase the recruitment potential and generalizability of a trial. Our method for automated structuring of criteria enables us to identify related conditions and to compare their restrictiveness. The comparison is based on the general meaning of criteria, comprised of commonly occurring contextual patterns, medical concepts and constraining values. These are automatically identified using our pattern detection algorithm, state of the art ontology annotators and semantic taggers. The comparison uses predefined relations between the patterns, concept equivalences defined in medical ontologies, and threshold values. The result is a library of structured eligibility criteria which can be browsed using fine grained queries. Furthermore, we developed visualizations for the library that enable intuitive navigation of relations between trials, criteria and concepts. These visualizations expose interesting co-occurrences and correlations, potentially enhancing meta-research. The method for criteria structuring processes only certain types of

  9. Serum IL-7 as diagnostic biomarker for rheumatoid arthritis, validation with EULAR 2010 classification criteria.

    Science.gov (United States)

    Burska, Agata N; Neilan, Jessica; Chisman, Ruth E; Pitaksalee, Rujiraporn; Hodgett, Richard; Marzo-Ortega, Helena; Conaghan, Philip G; West, Robert; Emery, Paul; Ponchel, Frederique

    2017-09-15

    Despite the well-established value of currently used classification criteria for the early diagnosis of rheumatoid arthritis (RA) there is a constant demand for novel biomarkers notably in autoantibody-negative patients. Interleukin 7 (IL-7) has been reported as a candidate diagnostic biomarker based on ACR-1987 criteria. However, clinical practice has moved to using the EULAR 2010 classification criteria. Therefore, to advance the use of IL-7 alongside the RA biomarker pipeline, we repeated the original study in a new cohort. 255 patients were recruited. IL-7 was quantified by ELISA. Univariate and regression analyses were used to model RA diagnosis. 123 patients were diagnosed with RA (EULAR 2010) while 132 were classified as non-RA. In univariate analysis, RA was associated with autoantibodies and SE-positivity, higher joint counts, DAS28 (all pEULAR 2010 criteria although the predictive power associated with IL-7 is lower than in the study using ACR 1987 criteria (both French/UK cohorts). IL-7 remains a potential biomarker for ACPA-negative RA although further validation with larger numbers of ACPA-negative patients is still needed notably to translate these results into clinical applicability.

  10. Evaluating educators using a novel toolbox: applying rigorous criteria flexibly across institutions.

    Science.gov (United States)

    Gusic, Maryellen E; Baldwin, Constance D; Chandran, Latha; Rose, Suzanne; Simpson, Deborah; Strobel, Henry W; Timm, Craig; Fincher, Ruth Marie E

    2014-07-01

    Valuing faculty as educators is essential for medical schools to fulfill their unique mission of educating physicians. The 2006 Consensus Conference on Educational Scholarship, sponsored by the Association of American Medical Colleges (AAMC) Group on Educational Affairs, provided educators seeking academic promotion with a portfolio-based format for documenting activities in five domains, using evidence of quantity, quality, a scholarly approach, and educational scholarship. Yet, the lack of a rigorous, widely accepted system to assess educator portfolio submissions during the promotion and tenure process continues to impede the ability to fully value educators and educational scholars.The AAMC Task Force on Educator Evaluation was formed in 2010 to establish consensus guidelines for use by those responsible for the rigorous evaluation of the educational contributions of faculty. The task force delineated the educational contributions currently valued by institutions and then fulfilled its charge by creating the Toolbox for Evaluating Educators, a resource which contains explicit evidence-based criteria to evaluate faculty in each of the five domains of educator activity. Adoption of such criteria is now the rate-limiting step in using a fair process to recognize educators through academic promotion. To inform institutional review and implementation of these criteria, this article describes the iterative, evidence- and stakeholder-based process to establish the criteria. The authors advocate institutional adoption of these criteria so that faculty seeking academic promotion as educators, like their researcher colleagues, can be judged and valued using established standards for the assessment of their work.

  11. Update on Rome IV Criteria for Colorectal Disorders: Implications for Clinical Practice.

    Science.gov (United States)

    Simren, Magnus; Palsson, Olafur S; Whitehead, William E

    2017-04-01

    The purpose of the review was to provide an update of the Rome IV criteria for colorectal disorders with implications for clinical practice. The Rome diagnostic criteria are expert consensus criteria for diagnosing functional gastrointestinal disorders (FGIDs). The current version, Rome IV, was released in May of 2016 after Rome III had been in effect for a decade. It is the collective product of committees that included more than 100 leading functional GI experts. For functional bowel and anorectal disorders, the majority of changes relative to Rome III are relatively minor and will have little impact on clinical practice. However, notable changes with potential impact on clinical practice and research include the changes in the diagnostic criteria for IBS, the modified approach for subtyping of IBS, the view on functional bowel disorders as a spectrum of disorders, and the new definition of fecal incontinence. New features in the Rome IV diagnostic criteria for functional bowel and anorectal disorders will likely have modest influence on clinical practice, with a few exceptions.

  12. Design criteria development for the structural stability of nuclear waste repository

    Energy Technology Data Exchange (ETDEWEB)

    Yun, C. H. [Korea Institute of Nuclear Safety, Taejon (Korea, Republic of); Yu, T. S. [Daewoo Engineering Company, Sungnam (Korea, Republic of); Ko, H. M. [Seoul National Univ., Seoul (Korea, Republic of)] (and others)

    1990-11-15

    The objective of the present project is to develop design criteria for the structural stability of rock cavity for the underground repository are defined, according to which detailed descriptions for design methodologies, design stages and stability analysis of the cavity are made. The proposed criteria can be used as a guide for the preparation of design codes which are to be established as the site condition and technical emplacement procedure are fixed. The present report first reviews basic safety requirements and criteria of the underground disposal of nuclear wastes for the establishment of design concepts and stability analysis of the rock cavity. Important factors for the design are also described by considering characteristics of the wastes and underground facilities. The present project has investigated technical aspects on the design of underground structures based on the currently established underground construction technologies, and presented a proposal for design criteria for the structural stability of the nuclear waste repository. The proposed criteria consist of general provisions, geological exploration, rock classification, design process and methods, supporting system, analyses and instrumentation.

  13. Core and peripheral criteria of video game addiction in the game addiction scale for adolescents.

    Science.gov (United States)

    Brunborg, Geir Scott; Hanss, Daniel; Mentzoni, Rune Aune; Pallesen, Ståle

    2015-05-01

    Assessment of video game addiction often involves measurement of peripheral criteria that indicate high engagement with games, and core criteria that indicate problematic use of games. A survey of the Norwegian population aged 16-74 years (N=10,081, response rate 43.6%) was carried out in 2013, which included the Gaming Addiction Scale for Adolescents (GAS). Confirmatory factor analysis showed that a two-factor structure, which separated peripheral criteria from core criteria, fitted the data better (CFI=0.963; RMSEA=0.058) compared to the original one-factor solution where all items are determined to load only on one factor (CFI=0.905, RMSEA=0.089). This was also found when we analyzed men aged ≤33 years, men aged >33 years, women aged ≤33 years, and women aged >33 years separately. This indicates that the GAS measures both engagement and problems related to video games. Multi-group measurement invariance testing showed that the factor structure was valid in all four groups (configural invariance) for the two-factor structure but not for the one-factor structure. A novel approach to categorization of problem gamers and addicted gamers where only the core criteria items are used (the CORE 4 approach) was compared to the approach where all items are included (the GAS 7 approach). The current results suggest that the CORE 4 approach might be more appropriate for classification of problem gamers and addicted gamers compared to the GAS 7 approach.

  14. Objectives for New Error Criteria for Mobile Broadcasting of Streaming Audiovisual Services

    Science.gov (United States)

    Himmanen, Heidi; Hannuksela, Miska M.; Kurki, Teppo; Isoaho, Jouni

    2008-12-01

    This paper demonstrates the need of and objectives for new error criteria for mobile broadcasting and the problems related to defining numerical error criteria for video services. The current error criterion used in digital video broadcasting to handheld (DVB-H), namely, multiprotocol encapsulation forward error correction (MPE-FEC) frame error ratio (MFER) 5%, was defined to enable instantaneous measurements but is not accurate enough for detailed simulations or postprocessing of measured data. To enable accurate transmission system design, parameter optimization, and performance evaluation, it is necessary to define new practical criteria for measuring the impact of transmission errors. The ambiguity of the MFER criterion is studied, and results for other conventional error criteria are derived from transmission system simulations and objective video quality measurements. The outcomes are compared to results from studies on subjective audiovisual quality. Guidelines are given on the next steps of developing new objective criteria for wireless and mobile video. It is suggested that subjective tests are performed based on the average length and average amount of errors derived from verified mobile radio channel models.

  15. On Model Selection Criteria in Multimodel Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Ye, Ming; Meyer, Philip D.; Neuman, Shlomo P.

    2008-03-21

    Hydrologic systems are open and complex, rendering them prone to multiple conceptualizations and mathematical descriptions. There has been a growing tendency to postulate several alternative hydrologic models for a site and use model selection criteria to (a) rank these models, (b) eliminate some of them and/or (c) weigh and average predictions and statistics generated by multiple models. This has led to some debate among hydrogeologists about the merits and demerits of common model selection (also known as model discrimination or information) criteria such as AIC [Akaike, 1974], AICc [Hurvich and Tsai, 1989], BIC [Schwartz, 1978] and KIC [Kashyap, 1982] and some lack of clarity about the proper interpretation and mathematical representation of each criterion. In particular, whereas we [Neuman, 2003; Ye et al., 2004, 2005; Meyer et al., 2007] have based our approach to multimodel hydrologic ranking and inference on the Bayesian criterion KIC (which reduces asymptotically to BIC), Poeter and Anderson [2005] and Poeter and Hill [2007] have voiced a preference for the information-theoretic criterion AICc (which reduces asymptotically to AIC). Their preference stems in part from a perception that KIC and BIC require a "true" or "quasi-true" model to be in the set of alternatives while AIC and AICc are free of such an unreasonable requirement. We examine the model selection literature to find that (a) all published rigorous derivations of AIC and AICc require that the (true) model having generated the observational data be in the set of candidate models; (b) though BIC and KIC were originally derived by assuming that such a model is in the set, BIC has been rederived by Cavanaugh and Neath [1999] without the need for such an assumption; (c) KIC reduces to BIC as the number of observations becomes large relative to the number of adjustable model parameters, implying that it likewise does not require the existence of a true model in the set of alternatives; (d) if a true

  16. The wave criteria for coastal zoning

    Science.gov (United States)

    Monnot, J. V.; Diez Gonzalez, J. J.; del Saz Cordero, S.

    2012-04-01

    THE WAVE CRITERIA FOR THE COASTAL ZONE DEFINITION Coastal nations define along their shores a strip of intense administrative intervention entailing strong restrictions to landowners domainial powers. The exact determination of the spatial extent of this zone is always blurred by coastal dynamics which cast some degree of legal uncertainty on the adjacent real rights. Criterion adopted for this determination shall seek to be practical enough to be effectively implemented, and at the same time robust enough in order to remain reliable at least in the mid term. In short, the aim of this paper is to integrate technical tools taken from coastal engineering and coastal law in order to better understand the relationship between human societies and the coastal substratum. The first step of our document aims to highlight those reasons that lead human societies to set back from the coast, and for this purpose we will proceed to a systematical scanning through the "Legal Findings" sections of several coastal laws. As a second step, we will make a review of the most common coastal features that constitute the final object of the administrative protection. Those coastal features, present in almost all coastal laws, are cliffs, dunes, wetlands and beaches, all of them closely related to waves. In this second point, the review will point out the reasons for the protection of those geomorphological elements and their role and utility for coastal human societies. The last part of this document will take advantage of the elements resulting from the first two steps in order to draw some conclusions. As a first achievement, and at the light of the fundamentals for coastal administrative protection identified in the first part, we will sort out a classification of coastal setbacks, according to the leading idea by which they are based. Finally will we will put into practice the concepts obtained from both the first and second steps - fundamentals for coastal administrative

  17. Swiftness movement evaluation criteria in women's rowing

    Directory of Open Access Journals (Sweden)

    Volodymyr Bogush

    2017-08-01

    Full Text Available Purpose: to develop criteria for assessing the speed capabilities of the pace of movement, time and speed of one movement, the frequency of movements that ensure the performance of motor actions in certain conditions of a specific period of time. Material & Methods: the girls, students of the Higher School of Physical Culture and university students, specializing in rowing, various age groups and sports qualification were surveyed, all 73 athletes. According to the method of measuring the effect of the training action developed by us, we studied the speed capabilities that characterize the manifestation of the quality of swiftness. On a special stand athletes made hand movements from the target to target. In the first period of the test, with a duration of 15 seconds, the athletes were to gain maximum speed; In the second period, with a duration of 60 s, it was necessary to maintain the achieved speed – distance velocity was investigated; in the third period – 15 seconds, speed endurance was determined – the athletes were supposed to perform the motor task with the maximum speed. The pace, time and speed of single movement, the frequency of movements were determined, and sensorimotor responses to sound and light stimuli were studied in modeling the conditions of training and competitive activity. Result: formation and improvement of motor abilities in specific age ranges is caused by high rates of development of morphological and functional indicators in sensitive periods. Obtained results characterize the individual psycho-physiological characteristics of the athlete's body in the context of modeling sports activities, show a different reaction in the observed age groups, a different level of sports qualification, which makes it possible to make adjustments in improving the speed abilities and effectively manage the training process. Conclusion: based on a comparative analysis of the studies that carried out, criteria were developed for

  18. Validation of the 2010 ACR/EULAR classification criteria for rheumatoid arthritis: slight improvement over the 1987 ACR criteria.

    Science.gov (United States)

    Britsemmer, Karin; Ursum, Jennie; Gerritsen, Martijn; van Tuyl, L H; van Tuyl, Lilian; van Schaardenburg, Dirkjan

    2011-08-01

    Recently, an American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) collaboration developed new classification criteria for rheumatoid arthritis (RA). To evaluate the diagnostic and discriminative ability of these new criteria compared with the 1987 ACR criteria and the Visser decision rule. 455 patients with early arthritis were studied. The diagnostic performance of the criteria was evaluated using methotrexate treatment within 1 year, expert opinion RA and erosive disease as 'gold standards'. Erosive disease was defined as a 0-3 year change in radiographic score of ≥5. The discriminative ability of the three criteria sets (2010 ACR/EULAR, 1987 ACR criteria and Visser algorithm) was similar with areas under the curve of 0.71-0.78 ('gold standard' methotrexate), 0.74-0.80 (gold standard expert opinion RA) and 0.63-0.67 (gold standard erosive disease after 3 years). The sensitivity of the 2010 ACR/EULAR criteria was highest with 0.85 (gold standard methotrexate). 86% of patients with RA and 51% of 'non-RA' patients according to the new criteria used methotrexate. The 2010 ACR/EULAR criteria were slightly more sensitive, but otherwise performed similarly to the older criteria. A high percentage of 'non-RA' patients used methotrexate, the gold standard for RA. The ability of the new criteria to identify patients with erosive disease was low, possibly owing to the effect of intensive treatment.

  19. Developmental trauma disorder: pros and cons of including formal criteria in the psychiatric diagnostic systems

    Directory of Open Access Journals (Sweden)

    Schmid Marc

    2013-01-01

    Full Text Available Abstract Background This article reviews the current debate on developmental trauma disorder (DTD with respect to formalizing its diagnostic criteria. Victims of abuse, neglect, and maltreatment in childhood often develop a wide range of age-dependent psychopathologies with various mental comorbidities. The supporters of a formal DTD diagnosis argue that post-traumatic stress disorder (PTSD does not cover all consequences of severe and complex traumatization in childhood. Discussion Traumatized individuals are difficult to treat, but clinical experience has shown that they tend to benefit from specific trauma therapy. A main argument against inclusion of formal DTD criteria into existing diagnostic systems is that emphasis on the etiology of the disorder might force current diagnostic systems to deviate from their purely descriptive nature. Furthermore, comorbidities and biological aspects of the disorder may be underdiagnosed using the DTD criteria. Summary Here, we discuss arguments for and against the proposal of DTD criteria and address implications and consequences for the clinical practice.

  20. Yield criteria for quasibrittle and frictional materials

    CERN Document Server

    Bigoni, Davide

    2010-01-01

    A new yield/damage function is proposed for modelling the inelastic behaviour of a broad class of pressure-sensitive, frictional, ductile and brittle-cohesive materials. The yield function allows the possibility of describing a transition between the shape of a yield surface typical of a class of materials to that typical of another class of materals. This is a fundamental key to model the behaviour of materials which become cohesive during hardening (so that the shape of the yield surface evolves from that typical of a granular material to that typical of a dense material), or which decrease cohesion due to damage accumulation. The proposed yield function is shown to agree with a variety of experimental data relative to soil, concrete, rock, metallic and composite powders, metallic foams, porous metals, and polymers. The yield function represents a single, convex and smooth surface in stress space approaching as limit situations well-known criteria and the extreme limits of convexity in the deviatoric plane....