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Sample records for current knowledge related

  1. Cancer Treatment-Related Cardiotoxicity: Understanding the Current State of Knowledge and Developing Future Research Priorities

    Science.gov (United States)

    Cancer Treatment-Related Cardiotoxicity: Understanding the Current State of Knowledge and Developing Future Research Priorities, a 2013 workshop sponsored by the Epidemiology and Genomics Research Program.

  2. [Cancer-related Cognitive Impairment: Current Knowledge and Future Challenges].

    Science.gov (United States)

    Tanimukai, Hitoshi

    2015-01-01

    Cancer patients often suffer from various distresses, including cognitive impairment. Cognitive impairment during and after cancer diagnosis and treatment are collectively called "Cancer-related cognitive impairment (CRCI)". The number of publications about cognitive impairment due to cancer therapy, especially chemotherapy, hormonal therapy, and radiotherapy, has been growing. Patients often worry not only about their disease condition and therapies, but also experience concerns regarding their memory, attention, and ability to concentrate. Even subtle CRCI can have a significant impact on social relationships, the ability to work, undergo treatment, accomplish meaningful goals, and the quality of life. Longitudinal studies of cancer patients indicated that up to 75% experience CRCI during treatment. Furthermore, CRCI may persist for many years following treatment. However, it is not well understood by most physicians and medical staff. CRCI can be mediated through increased inflammatory cytokines and hormonal changes. In addition, the biology of the cancer, stress, and attentional fatigue can also contribute to CRCI. Genetic factors and co-occurring symptoms may explain some of the inter-individual variability in CRCI. Researchers and patients are actively trying to identify effective interventional methods and useful coping strategies. Many patients are willing to discuss their disease condition and future treatment with medical staff and/or their families. Some patients also hope to discuss their end-of-life care. However, it is difficult to express their will after developing cognitive impairment. Advance care planning (ACP) can help in such situations. This process involves discussion between a patient, their family, and clinicians to clarify and reflect on values, treatment preferences, and goals to develop a shared understanding of how end-of-life care should proceed. The number of cancer patients with cognitive impairment has been increasing owing to the

  3. The enigmatic role of RUNX1 in female-related cancers - current knowledge & future perspectives.

    Science.gov (United States)

    Riggio, Alessandra I; Blyth, Karen

    2017-08-01

    Historically associated with the aetiology of human leukaemia, the runt-related transcription factor 1 (RUNX1) gene has in recent years reared its head in an assortment of epithelial cancers. This review discusses the state-of-the-art knowledge of the enigmatic role played by RUNX1 in female-related cancers of the breast, the uterus and the ovary. The weight of evidence accumulated so far is indicative of a very context-dependent role, as either an oncogene or a tumour suppressor. This is corroborated by high-throughput sequencing endeavours which report different genetic alterations affecting the gene, including amplification, deep deletion and mutations. Herein, we attempt to dissect that contextual role by firstly giving an overview of what is currently known about RUNX1 function in these specific tumour types, and secondly by delving into connections between this transcription factor and the physiology of these female tissues. In doing so, RUNX1 emerges not only as a gene involved in female sex development but also as a crucial mediator of female hormone signalling. In view of RUNX1 now being listed as a driver gene, we believe that greater knowledge of the mechanisms underlying its functional dualism in epithelial cancers is worthy of further investigation. © 2017 Federation of European Biochemical Societies.

  4. Summary of knowledge gaps related to quality and efficacy of current influenza vaccines.

    Science.gov (United States)

    Pfleiderer, Michael; Trouvin, Jean-Hugues; Brasseur, Daniel; Gränstrom, Marta; Shivji, Ragini; Mura, Manuela; Cavaleri, Marco

    2014-07-31

    Influenza viruses are a public health threat, as they are pathogenic, highly transmissible and prone to genetic changes. For decades vaccination strategies have been based on trivalent inactivated vaccines, which are regulated by specific guidelines. The progress in scientific knowledge and the lessons learned from the A(H1N1)2009 pandemic have highlighted further the need to improve current guidelines, including the immunogenicity criteria set by the CHMP in 1997, and to promote the discussion on the shortcomings encountered, e.g. the evaluation of vaccine efficacy in the paediatric and elderly populations, the measurement of the naivety of a population, the impact of prior immunity on subsequent vaccinations, and the technical issues with the serological assays for detection of immunity and immunogenicity. The authors attempted to summarise and tackle key gaps in the existing evidence concerning quality and efficacy of influenza vaccines, aiming at favouring a common understanding and a coordinated approach across stakeholders.

  5. Current Knowledge of Leishmania Vectors in Mexico: How Geographic Distributions of Species Relate to Transmission Areas

    Science.gov (United States)

    González, Camila; Rebollar-Téllez, Eduardo A.; Ibáñez-Bernal, Sergio; Becker-Fauser, Ingeborg; Martínez-Meyer, Enrique; Peterson, A. Townsend; Sánchez-Cordero, Víctor

    2011-01-01

    Leishmaniases are a group of vector-borne diseases with different clinical manifestations caused by parasites transmitted by sand fly vectors. In Mexico, the sand fly Lutzomyia olmeca olmeca is the only vector proven to transmit the parasite Leishmania mexicana to humans, which causes leishmaniasis. Other vector species with potential medical importance have been obtained, but their geographic distributions and relation to transmission areas have never been assessed. We modeled the ecological niches of nine sand fly species and projected niches to estimate potential distributions by using known occurrences, environmental coverages, and the algorithms GARP and Maxent. All vector species were distributed in areas with known recurrent transmission, except for Lu. diabolica, which appeared to be related only to areas of occasional transmission in northern Mexico. The distribution of Lu. o. olmeca does not overlap with all reported cutaneous leishmaniasis cases, suggesting that Lu. cruciata and Lu. shannoni are likely also involved as primary vectors in those areas. Our study provides useful information of potential risk areas of leishmaniasis transmission in Mexico. PMID:22049037

  6. Current knowledge on esophageal atresia

    Institute of Scientific and Technical Information of China (English)

    Paulo Fernando Martins Pinheiro; Ana Cristina Sim(o)es e Silva; Regina Maria Pereira

    2012-01-01

    Esophageal atresia (EA) with or without tracheoesophageal fistula (TEF) is the most common congenital anomaly of the esophagus.The improvement of survival observed over the previous two decades is multifactorial and largely attributable to advances in neonatal intensive care,neonatal anesthesia,ventilatory and nutritional support,antibiotics,early surgical intervention,surgical materials and techniques.Indeed,mortality is currently limited to those cases with coexisting severe life-threatening anomalies.The diagnosis of EA is most commonly made during the first 24 h of life but may occur either antenatally or may be delayed.The primary surgical correction for EA and TEF is the best option in the absence of severe malformations.There is no ideal replacement for the esophagus and the optimal surgical treatment for patients with long-gap EA is still controversial.The primary complications during the postoperative period are leak and stenosis of the anastomosis,gastro-esophageal reflux,esophageal dysmotility,fistula recurrence,respiratory disorders and deformities of the thoracic wall.Data regarding long-term outcomes and follow-ups are limited for patients following EA/TEF repair.The determination of the risk factors for the complicated evolution following EA/TEF repair may positively impact long-term prognoses.Much remains to be studied regarding this condition.This manuscript provides a literature review of the current knowledge regarding EA.

  7. Dietary Magnesium and Genetic Interactions in Diabetes and Related Risk Factors: A Brief Overview of Current Knowledge

    Directory of Open Access Journals (Sweden)

    Adela Hruby

    2013-12-01

    Full Text Available Nutritional genomics has exploded in the last decade, yielding insights—both nutrigenomic and nutrigenetic—into the physiology of dietary interactions and our genes. Among these are insights into the regulation of magnesium transport and homeostasis and mechanisms underlying magnesium’s role in insulin and glucose handling. Recent observational evidence has attempted to examine some promising research avenues on interaction between genetics and dietary magnesium in relation to diabetes and diabetes risk factors. This brief review summarizes the recent evidence on dietary magnesium’s role in diabetes and related traits in the presence of underlying genetic risk, and discusses future potential research directions.

  8. Current Knowledge on Hepatitis E.

    Science.gov (United States)

    Pérez-Gracia, María Teresa; García, Mario; Suay, Beatriz; Mateos-Lindemann, María Luisa

    2015-06-28

    Although only a single serotype of hepatitis E virus (HEV), the causative agent of hepatitis E, has been identified, there is great genetic variation among the different HEV isolates reported. There are at least four major recognized genotypes of HEV: genotypes 1 and 2 are mainly restricted to humans and linked to epidemic outbreaks in nonindustrialized countries, whereas genotypes 3 and 4 are zoonotic in both developing and industrialized countries. Besides human strains, genotype 3 and 4 strains of HEV have been genetically characterized from swine, sika deer, mongooses, sheep, and rabbits. Currently, there are approximately 11,000 human and animal sequences of HEV available at the International Nucleotide Sequence Database Collaboration. HEV is the major cause of waterborne outbreaks of hepatitis in areas of poor sanitation. Additionally, it is responsible for sporadic cases of viral hepatitis in not only endemic but industrialized countries as well. Transmission of HEV occurs predominantly by the fecal-oral route, although parenteral and perinatal routes have been reported. HEV infection develops in most individuals as a self-limiting, acute, icteric hepatitis; with mortality rates around 1%. However, some affected individuals will develop fulminant hepatic failure, a serious condition that is frequently fatal without a liver transplant. This complication is particularly common when the infection occurs in pregnant women, where mortality rates rise dramatically to up to 25%. Among the preventive measures available to avoid HEV infection, two separate subunit vaccines containing recombinant truncated capsid proteins of HEV have been shown to be highly effective in the prevention of disease. One of them, HEV 239, was approved in China, and its commercialization by Innovax began in November 2012 under the name Hecolin(®).

  9. Knowledge Repository for Fmea Related Knowledge

    Science.gov (United States)

    Cândea, Gabriela Simona; Kifor, Claudiu Vasile; Cândea, Ciprian

    2014-11-01

    This paper presents innovative usage of knowledge system into Failure Mode and Effects Analysis (FMEA) process using the ontology to represent the knowledge. Knowledge system is built to serve multi-projects work that nowadays are in place in any manufacturing or services provider, and knowledge must be retained and reused at the company level and not only at project level. The system is following the FMEA methodology and the validation of the concept is compliant with the automotive industry standards published by Automotive Industry Action Group, and not only. Collaboration is assured trough web-based GUI that supports multiple users access at any time

  10. Loyalty Programmes : Current Knowledge and Research Directions

    NARCIS (Netherlands)

    Dorotic, Matilda; Bijmolt, Tammo H. A.; Verhoef, Peter C.

    2012-01-01

    Loyalty programmes (LPs) have increased in number and popularity, but their effects on customer behaviour remain equivocal, due to a lack of understanding of the drivers of LP effectiveness and insufficient generalizable conclusions across prior studies. This paper synthesizes current knowledge pert

  11. Loyalty Programmes : Current Knowledge and Research Directions

    NARCIS (Netherlands)

    Dorotic, Matilda; Bijmolt, Tammo H. A.; Verhoef, Peter C.

    Loyalty programmes (LPs) have increased in number and popularity, but their effects on customer behaviour remain equivocal, due to a lack of understanding of the drivers of LP effectiveness and insufficient generalizable conclusions across prior studies. This paper synthesizes current knowledge

  12. Loyalty Programmes : Current Knowledge and Research Directions

    NARCIS (Netherlands)

    Dorotic, Matilda; Bijmolt, Tammo H. A.; Verhoef, Peter C.

    2012-01-01

    Loyalty programmes (LPs) have increased in number and popularity, but their effects on customer behaviour remain equivocal, due to a lack of understanding of the drivers of LP effectiveness and insufficient generalizable conclusions across prior studies. This paper synthesizes current knowledge pert

  13. Human bocavirus: Current knowledge and future challenges

    Science.gov (United States)

    Guido, Marcello; Tumolo, Maria Rosaria; Verri, Tiziano; Romano, Alessandro; Serio, Francesca; De Giorgi, Mattia; De Donno, Antonella; Bagordo, Francesco; Zizza, Antonella

    2016-01-01

    Human bocavirus (HBoV) is a parvovirus isolated about a decade ago and found worldwide in both respiratory samples, mainly from early life and children of 6-24 mo of age with acute respiratory infection, and in stool samples, from patients with gastroenteritis. Since then, other viruses related to the first HBoV isolate (HBoV1), namely HBoV2, HBoV3 and HBoV4, have been detected principally in human faeces. HBoVs are small non-enveloped single-stranded DNA viruses of about 5300 nucleotides, consisting of three open reading frames encoding the first two the non-structural protein 1 (NS1) and nuclear phosphoprotein (NP1) and the third the viral capsid proteins 1 and 2 (VP1 and VP2). HBoV pathogenicity remains to be fully clarified mainly due to the lack of animal models for the difficulties in replicating the virus in in vitro cell cultures, and the fact that HBoV infection is frequently accompanied by at least another viral and/or bacterial respiratory and/or gastroenteric pathogen infection. Current diagnostic methods to support HBoV detection include polymerase chain reaction, real-time PCR, enzyme-linked immunosorbent assay and enzyme immunoassay using recombinant VP2 or virus-like particle capsid proteins, although sequence-independent amplification techniques combined with next-generation sequencing platforms promise rapid and simultaneous detection of the pathogens in the future. This review presents the current knowledge on HBoV genotypes with emphasis on taxonomy, phylogenetic relationship and genomic analysis, biology, epidemiology, pathogenesis and diagnostic methods. The emerging discussion on HBoVs as true pathogen or innocent bystander is also emphasized.

  14. Changing Clinical Presentation, Current Knowledge-Attitude-Practice, and Current Vision Related Quality of Life in Self-Reported Type 2 Diabetes Patients with Retinopathy in Eastern India: The LVPEI Eye and Diabetes Study.

    Science.gov (United States)

    Das, Taraprasad; Wallang, Batriti; Semwal, Preeti; Basu, Soumyava; Padhi, Tapas R; Ali, Mohd Hasnat

    2016-01-01

    Purpose. To document the changing clinical presentation of diabetic retinopathy (DR) over a decade, the current knowledge-attitude-practice (KAP) of known type 2 diabetes mellitus (DM) patients, and the current vision related quality of life (VR-QOL) of patients with DR in a tertiary eye care center in Eastern India. Methods. Two hundred and forty patients with known type-2 DM were evaluated. The evaluation included status of DR (n = 240), KAP (n = 232), and VR-QOL (n = 75). International classification of DR was used in the study. The DR status was compared with another cohort (n = 472) examined a decade earlier, in year 2001. The KAP-25 questions were designed after literature review. The National Eye Institute Visual Function Questionnaire (NEI-VFQ; including optional items) was validated by Rasch analysis. Both KAP and VR-QOL were analyzed according to degree of DR, duration of known DM, and educational qualification. Results. Average age of the current cohort (n = 240) was 57.16 ± 9.03 years; there were 205 (85.4%) male patients and 143 (59.6%) patients had received less than graduate qualification. The mean duration of DM since diagnosis was 10 ± 7.8 months (range 8 months to 30 years); 118 (49.16%) patients had DR. In a decade time, 2001 to 2011, there was a change of retinopathy status at presentation (more often nonproliferative diabetic retinopathy, NPDR). One-third of NPDR patients had poor vision and half of them were hypertensive. KAP was better in patients with higher education and those having DR. VFQ score was higher in better seeing patients. Conclusion. Patients currently presenting at earlier stage of retinopathy are probably related to poor vision. Early detection and treatment of DR is likely to preserve and/or improve vision.

  15. Changing Clinical Presentation, Current Knowledge-Attitude-Practice, and Current Vision Related Quality of Life in Self-Reported Type 2 Diabetes Patients with Retinopathy in Eastern India: The LVPEI Eye and Diabetes Study

    Directory of Open Access Journals (Sweden)

    Taraprasad Das

    2016-01-01

    Full Text Available Purpose. To document the changing clinical presentation of diabetic retinopathy (DR over a decade, the current knowledge-attitude-practice (KAP of known type 2 diabetes mellitus (DM patients, and the current vision related quality of life (VR-QOL of patients with DR in a tertiary eye care center in Eastern India. Methods. Two hundred and forty patients with known type-2 DM were evaluated. The evaluation included status of DR (n=240, KAP (n=232, and VR-QOL (n=75. International classification of DR was used in the study. The DR status was compared with another cohort (n=472 examined a decade earlier, in year 2001. The KAP-25 questions were designed after literature review. The National Eye Institute Visual Function Questionnaire (NEI-VFQ; including optional items was validated by Rasch analysis. Both KAP and VR-QOL were analyzed according to degree of DR, duration of known DM, and educational qualification. Results. Average age of the current cohort (n=240 was 57.16 ± 9.03 years; there were 205 (85.4% male patients and 143 (59.6% patients had received less than graduate qualification. The mean duration of DM since diagnosis was 10 ± 7.8 months (range 8 months to 30 years; 118 (49.16% patients had DR. In a decade time, 2001 to 2011, there was a change of retinopathy status at presentation (more often nonproliferative diabetic retinopathy, NPDR. One-third of NPDR patients had poor vision and half of them were hypertensive. KAP was better in patients with higher education and those having DR. VFQ score was higher in better seeing patients. Conclusion. Patients currently presenting at earlier stage of retinopathy are probably related to poor vision. Early detection and treatment of DR is likely to preserve and/or improve vision.

  16. Current Levels of Salt Knowledge: A Review of the Literature

    Directory of Open Access Journals (Sweden)

    Rani Sarmugam

    2014-12-01

    Full Text Available High salt intake increases the risk of hypertension and cardiovascular diseases. Given the role of knowledge as a determinant of food intake, this paper aims to review the current levels of salt knowledge and the association between salt knowledge and dietary salt intake and salt-related dietary practices in the general population. Twenty two studies were included in the review. In general, the studies showed consumers were able to identify the health risks associated with high salt intake. However, knowledge of recommended daily intakes, understanding of the relationships between salt and sodium and foods that contribute most salt to the diet were poor. Four of the five studies which examined the relationships between salt knowledge and salt-related dietary practices reported significant associations. Two important gaps in the current literature were identified. First, there is a need for a robustly validated tool to examine salt knowledge and its impact on salt intake. Second, a comprehensive salt knowledge assessment should include assessment of procedural, as well as declarative, knowledge.

  17. Methicillin-resistant food-related Staphylococcus aureus: a review of current knowledge and biofilm formation for future studies and applications.

    Science.gov (United States)

    Doulgeraki, Agapi I; Di Ciccio, Pierluigi; Ianieri, Adriana; Nychas, George-John E

    2017-01-01

    There is increasing concern about the public health impact of methicillin-resistant Staphylococcus aureus. Food and animal are vectors of transmission, but the contribution of a contaminated environment is not well characterized. With regard to this, staphylococcal biofilms serve as a virulence factor, allowing MRSA strains to adhere to surfaces and other materials used in the food industry. Methicillin resistance and biofilm-forming capacity may contribute to the success of S. aureus as a human pathogen in both health care and community settings and the food production chain. This review summarizes current knowledge about the significance of food- and animal-derived MRSA strains and provides data on attachment and biofilm formation of MRSA. In addition, the impact of quorum sensing on MRSA gene expression and biofilm formation is examined.

  18. [Hypnosis and pain: current and perspective knowledge].

    Science.gov (United States)

    Bioy, Antoine

    2012-06-27

    After further controversies, the definition of hypnosis is to be at the same time a modified state of consciousness and a particular intersubjective relation between a practitioner and his patient. In a synthetic way, we can say that mechanisms of hypnosis on acute pain are now well known, and its efficiency is particularly proved in the pain provoked by the care. On the other hand, the knowledge concerning the action of the hypnosis on chronic pain is much more complex to understand. If the hypnosis allows connoting differently pain and to decrease its implication in patient's life, otherWise the long-term reorganizations of hypnosis on chronic pain are still for the study. In practice, the field which his particularly in development is the analogical processes of the speech, because they are particularly present in pain medicine, and easy to use in hypnotic method.

  19. Current trends on knowledge-based systems

    CERN Document Server

    Valencia-García, Rafael

    2017-01-01

    This book presents innovative and high-quality research on the implementation of conceptual frameworks, strategies, techniques, methodologies, informatics platforms and models for developing advanced knowledge-based systems and their application in different fields, including Agriculture, Education, Automotive, Electrical Industry, Business Services, Food Manufacturing, Energy Services, Medicine and others. Knowledge-based technologies employ artificial intelligence methods to heuristically address problems that cannot be solved by means of formal techniques. These technologies draw on standard and novel approaches from various disciplines within Computer Science, including Knowledge Engineering, Natural Language Processing, Decision Support Systems, Artificial Intelligence, Databases, Software Engineering, etc. As a combination of different fields of Artificial Intelligence, the area of Knowledge-Based Systems applies knowledge representation, case-based reasoning, neural networks, Semantic Web and TICs used...

  20. The Influence of Relational Knowledge and Executive Function on Preschoolers' Repeating Pattern Knowledge

    Science.gov (United States)

    Miller, Michael R.; Rittle-Johnson, Bethany; Loehr, Abbey M.; Fyfe, Emily R.

    2016-01-01

    Children's knowledge of repeating patterns (e.g., ABBABB) is a central component of early mathematics, but the developmental mechanisms underlying this knowledge are currently unknown. We sought clarity on the importance of relational knowledge and executive function (EF) to preschoolers' understanding of repeating patterns. One hundred…

  1. Students' Wisdom Related Knowledge as Expertise

    Science.gov (United States)

    Plavšic, Marlena; Ambrosi-Randic, Neala

    2016-01-01

    Wisdom, as a form of cognitive functioning, includes different types of knowledge and values, and it seems that increasing the knowledge about the world and different experiences may facilitate their development. School system usually pays more attention to accumulation of knowledge, but little related to wisdom. In this study wisdom…

  2. Knowledge work and work-related stress

    OpenAIRE

    Ipsen, Christine

    2006-01-01

    Work-related stress is an increasing problem in Europe. Earlier studies have stated that knowledge-work comprises working conditions which reflect a good psychosocial environment. Recent Danish studies, however, point at stress being an increasing problem in knowledge-intensive companies. These companies employ highly educated and com-petent people who apply their personal knowledge to generate new knowledge in close relationship with both custom-ers and colleagues. The employees are self-man...

  3. Elder Abuse: The Status of Current Knowledge.

    Science.gov (United States)

    Pedrick-Cornell, Claire; Gelles, Richard J.

    1982-01-01

    Discusses problems of definition of elderly abuse. Examines data and research on the rates of elderly abuse and factors found related to elderly abuse. Critiques theories developed to explain the abuse of the elderly. Presents recommendations for research and practice. (RC)

  4. Sleep bruxism: Current knowledge and contemporary management.

    Science.gov (United States)

    Yap, Adrian U; Chua, Ai Ping

    2016-01-01

    Bruxism is defined as the repetitive jaw muscle activity characterized by the clenching or grinding of teeth. It can be categorized into awake and sleep bruxism (SB). Frequent SB occurs in about 13% of adults. The exact etiology of SB is still unknown and probably multifactorial in nature. Current literature suggests that SB is regulated centrally (pathophysiological and psychosocial factors) and not peripherally (morphological factors). Cited consequences of SB include temporomandibular disorders, headaches, tooth wear/fracture, implant, and other restoration failure. Chairside recognition of SB involves the use of subjective reports, clinical examinations, and trial oral splints. Definitive diagnosis of SB can only be achieved using electrophysiological tools. Pharmacological, psychological, and dental strategies had been employed to manage SB. There is at present, no effective treatment that "cures" or "stops" SB permanently. Management is usually directed toward tooth/restoration protection, reduction of bruxism activity, and pain relief.

  5. Sleep bruxism: Current knowledge and contemporary management

    Directory of Open Access Journals (Sweden)

    Adrian U.J. Yap

    2016-01-01

    Full Text Available Bruxism is defined as the repetitive jaw muscle activity characterized by the clenching or grinding of teeth. It can be categorized into awake and sleep bruxism (SB. Frequent SB occurs in about 13% of adults. The exact etiology of SB is still unknown and probably multifactorial in nature. Current literature suggests that SB is regulated centrally (pathophysiological and psychosocial factors and not peripherally (morphological factors. Cited consequences of SB include temporomandibular disorders, headaches, tooth wear/fracture, implant, and other restoration failure. Chairside recognition of SB involves the use of subjective reports, clinical examinations, and trial oral splints. Definitive diagnosis of SB can only be achieved using electrophysiological tools. Pharmacological, psychological, and dental strategies had been employed to manage SB. There is at present, no effective treatment that “cures” or “stops” SB permanently. Management is usually directed toward tooth/restoration protection, reduction of bruxism activity, and pain relief.

  6. Sleep bruxism: Current knowledge and contemporary management

    Science.gov (United States)

    Yap, Adrian U.; Chua, Ai Ping

    2016-01-01

    Bruxism is defined as the repetitive jaw muscle activity characterized by the clenching or grinding of teeth. It can be categorized into awake and sleep bruxism (SB). Frequent SB occurs in about 13% of adults. The exact etiology of SB is still unknown and probably multifactorial in nature. Current literature suggests that SB is regulated centrally (pathophysiological and psychosocial factors) and not peripherally (morphological factors). Cited consequences of SB include temporomandibular disorders, headaches, tooth wear/fracture, implant, and other restoration failure. Chairside recognition of SB involves the use of subjective reports, clinical examinations, and trial oral splints. Definitive diagnosis of SB can only be achieved using electrophysiological tools. Pharmacological, psychological, and dental strategies had been employed to manage SB. There is at present, no effective treatment that “cures” or “stops” SB permanently. Management is usually directed toward tooth/restoration protection, reduction of bruxism activity, and pain relief. PMID:27656052

  7. Class IIa Bacteriocins: Current Knowledge and Perspectives

    Science.gov (United States)

    Belguesmia, Yanath; Naghmouchi, Karim; Chihib, Nour-Eddine; Drider, Djamel

    Lactic acid bacteria (LAB) are known to produce antibacterial peptides and small proteins called bacteriocins, which enable them to compete against other bacteria in the environment. Bacteriocins fall structurally and chemically into three different classes, I, II, and III. Bacteriocins are ribosomally synthesized peptides with antagonism against closely related bacteria. This late observation has evolved because bacteriocins active against Gram-negative bacteria have recently been reported. Members of class IIa bacteriocins, referred to as pediocin-like bacteriocins, are among the most studied bacteriocins. This chapter is aimed at providing an updated review on the biology of class IIa bacteriocins.

  8. [Schizophrenic disorders: current etiologic and clinical knowledge].

    Science.gov (United States)

    Olié, Jean-Pierre; Krebs, Marie-Odile; Lôo, Henri

    2005-05-01

    Brain anomalies associated with schizophrenic disorders may be of a cognitive, neurophysiological or neurological nature [the latter being relatively minor and nonspecific]. Brain imaging has revealed early anomalies such as cortical-subcortical atrophy and abnormal gyration. These anomalies can also be present in relatives free of schizophrenic symptoms. This raises the question of what determines the transition from vulnerability to clinical onset. There is now evidence that schizophrenic disorders are true brain diseases. This is based on neuropathological studies, brain imaging and clinical findings such as "soft" neurological signs (pyramidal and extrapyramidal symptoms, coordination difficulties, etc.). Cognitive dysfunctions such as attention and memory disorders and abnormal verbal fluency have also been described. Oculomotor pursuit and auditive evoked potentials have identified specific neurophysiological disorders such as N300 and P50 wave modifications. Schizophrenic disorders can also be associated with neuronal abnormalities, notably affecting factors involved in synaptic transmission and plasticity. For example, BDNF protein deficit is linked to certain late-onset forms of schizophrenia. Genetic studies are no longer focusing on a possible disease genotype but rather on phenotypic characteristics determined by simpler genotypes (P50 wave modulation, COMT and BDNF genes). The ultimate objective is to identify high-risk subjects, in order to shorten the treatment delay and thereby improve long-term outcome. The benefit of primary prophylaxis remains to be determined, however.

  9. Cetacean Morbillivirus: Current Knowledge and Future Directions

    Directory of Open Access Journals (Sweden)

    Marie-Françoise Van Bressem

    2014-12-01

    Full Text Available We review the molecular and epidemiological characteristics of cetacean morbillivirus (CeMV and the diagnosis and pathogenesis of associated disease, with six different strains detected in cetaceans worldwide. CeMV has caused epidemics with high mortality in odontocetes in Europe, the USA and Australia. It represents a distinct species within the Morbillivirus genus. Although most CeMV strains are phylogenetically closely related, recent data indicate that morbilliviruses recovered from Indo-Pacific bottlenose dolphins (Tursiops aduncus, from Western Australia, and a Guiana dolphin (Sotalia guianensis, from Brazil, are divergent. The signaling lymphocyte activation molecule (SLAM cell receptor for CeMV has been characterized in cetaceans. It shares higher amino acid identity with the ruminant SLAM than with the receptors of carnivores or humans, reflecting the evolutionary history of these mammalian taxa. In Delphinidae, three amino acid substitutions may result in a higher affinity for the virus. Infection is diagnosed by histology, immunohistochemistry, virus isolation, RT-PCR, and serology. Classical CeMV-associated lesions include bronchointerstitial pneumonia, encephalitis, syncytia, and lymphoid depletion associated with immunosuppression. Cetaceans that survive the acute disease may develop fatal secondary infections and chronic encephalitis. Endemically infected, gregarious odontocetes probably serve as reservoirs and vectors. Transmission likely occurs through the inhalation of aerosolized virus but mother to fetus transmission was also reported.

  10. Cetacean morbillivirus: current knowledge and future directions.

    Science.gov (United States)

    Van Bressem, Marie-Françoise; Duignan, Pádraig J; Banyard, Ashley; Barbieri, Michelle; Colegrove, Kathleen M; De Guise, Sylvain; Di Guardo, Giovanni; Dobson, Andrew; Domingo, Mariano; Fauquier, Deborah; Fernandez, Antonio; Goldstein, Tracey; Grenfell, Bryan; Groch, Kátia R; Gulland, Frances; Jensen, Brenda A; Jepson, Paul D; Hall, Ailsa; Kuiken, Thijs; Mazzariol, Sandro; Morris, Sinead E; Nielsen, Ole; Raga, Juan A; Rowles, Teresa K; Saliki, Jeremy; Sierra, Eva; Stephens, Nahiid; Stone, Brett; Tomo, Ikuko; Wang, Jianning; Waltzek, Thomas; Wellehan, James F X

    2014-12-22

    We review the molecular and epidemiological characteristics of cetacean morbillivirus (CeMV) and the diagnosis and pathogenesis of associated disease, with six different strains detected in cetaceans worldwide. CeMV has caused epidemics with high mortality in odontocetes in Europe, the USA and Australia. It represents a distinct species within the Morbillivirus genus. Although most CeMV strains are phylogenetically closely related, recent data indicate that morbilliviruses recovered from Indo-Pacific bottlenose dolphins (Tursiops aduncus), from Western Australia, and a Guiana dolphin (Sotalia guianensis), from Brazil, are divergent. The signaling lymphocyte activation molecule (SLAM) cell receptor for CeMV has been characterized in cetaceans. It shares higher amino acid identity with the ruminant SLAM than with the receptors of carnivores or humans, reflecting the evolutionary history of these mammalian taxa. In Delphinidae, three amino acid substitutions may result in a higher affinity for the virus. Infection is diagnosed by histology, immunohistochemistry, virus isolation, RT-PCR, and serology. Classical CeMV-associated lesions include bronchointerstitial pneumonia, encephalitis, syncytia, and lymphoid depletion associated with immunosuppression. Cetaceans that survive the acute disease may develop fatal secondary infections and chronic encephalitis. Endemically infected, gregarious odontocetes probably serve as reservoirs and vectors. Transmission likely occurs through the inhalation of aerosolized virus but mother to fetus transmission was also reported.

  11. Cetacean Morbillivirus: Current Knowledge and Future Directions

    Science.gov (United States)

    Van Bressem, Marie-Françoise; Duignan, Pádraig J.; Banyard, Ashley; Barbieri, Michelle; Colegrove, Kathleen M; De Guise, Sylvain; Di Guardo, Giovanni; Dobson, Andrew; Domingo, Mariano; Fauquier, Deborah; Fernandez, Antonio; Goldstein, Tracey; Grenfell, Bryan; Groch, Kátia R.; Gulland, Frances; Jensen, Brenda A; Jepson, Paul D; Hall, Ailsa; Kuiken, Thijs; Mazzariol, Sandro; Morris, Sinead E; Nielsen, Ole; Raga, Juan A; Rowles, Teresa K; Saliki, Jeremy; Sierra, Eva; Stephens, Nahiid; Stone, Brett; Tomo, Ikuko; Wang, Jianning; Waltzek, Thomas; Wellehan, James FX

    2014-01-01

    We review the molecular and epidemiological characteristics of cetacean morbillivirus (CeMV) and the diagnosis and pathogenesis of associated disease, with six different strains detected in cetaceans worldwide. CeMV has caused epidemics with high mortality in odontocetes in Europe, the USA and Australia. It represents a distinct species within the Morbillivirus genus. Although most CeMV strains are phylogenetically closely related, recent data indicate that morbilliviruses recovered from Indo-Pacific bottlenose dolphins (Tursiops aduncus), from Western Australia, and a Guiana dolphin (Sotalia guianensis), from Brazil, are divergent. The signaling lymphocyte activation molecule (SLAM) cell receptor for CeMV has been characterized in cetaceans. It shares higher amino acid identity with the ruminant SLAM than with the receptors of carnivores or humans, reflecting the evolutionary history of these mammalian taxa. In Delphinidae, three amino acid substitutions may result in a higher affinity for the virus. Infection is diagnosed by histology, immunohistochemistry, virus isolation, RT-PCR, and serology. Classical CeMV-associated lesions include bronchointerstitial pneumonia, encephalitis, syncytia, and lymphoid depletion associated with immunosuppression. Cetaceans that survive the acute disease may develop fatal secondary infections and chronic encephalitis. Endemically infected, gregarious odontocetes probably serve as reservoirs and vectors. Transmission likely occurs through the inhalation of aerosolized virus but mother to fetus transmission was also reported. PMID:25533660

  12. Relations among conceptual knowledge, procedural knowledge, and procedural flexibility in two samples differing in prior knowledge.

    Science.gov (United States)

    Schneider, Michael; Rittle-Johnson, Bethany; Star, Jon R

    2011-11-01

    Competence in many domains rests on children developing conceptual and procedural knowledge, as well as procedural flexibility. However, research on the developmental relations between these different types of knowledge has yielded unclear results, in part because little attention has been paid to the validity of the measures or to the effects of prior knowledge on the relations. To overcome these problems, we modeled the three constructs in the domain of equation solving as latent factors and tested (a) whether the predictive relations between conceptual and procedural knowledge were bidirectional, (b) whether these interrelations were moderated by prior knowledge, and (c) how both constructs contributed to procedural flexibility. We analyzed data from 2 measurement points each from two samples (Ns = 228 and 304) of middle school students who differed in prior knowledge. Conceptual and procedural knowledge had stable bidirectional relations that were not moderated by prior knowledge. Both kinds of knowledge contributed independently to procedural flexibility. The results demonstrate how changes in complex knowledge structures contribute to competence development.

  13. Knowledge work and work-related stress

    DEFF Research Database (Denmark)

    Ipsen, Christine

    2006-01-01

    Work-related stress is an increasing problem in Europe. Earlier studies have stated that knowledge-work comprises working conditions which reflect a good psychosocial environment. Recent Danish studies, however, point at stress being an increasing problem in knowledge-intensive companies...... as good and stimulating, but has on the other hand sides to it which can cause frustration and stress. The implication of organisational characteristics of the knowledge-intensive companies studied is a transfer of the responsibility for ones own working-life. Consequently, issues are dealt...... with informally, individu-ally and incidentally. It is only when problems exist that enhanced support is offered in order to help an employee to cope or recover. As most workplace initiatives work at this tertiary level, the sources of work-related and organiza-tional stress are not reduced or eliminated...

  14. Marine aerosol production: a review of the current knowledge

    NARCIS (Netherlands)

    O'Dowd, C.D.; Leeuw, G. de

    2007-01-01

    The current knowledge in primary and secondary marine aerosol formation is reviewed. For primary marine aerosol source functions, recent source functions have demonstrated a significant flux of submicrometre particles down to radii of 20 nm. Moreover, the source functions derived from different tech

  15. Diuretics in pediatrics: Current knowledge and future prospects

    NARCIS (Netherlands)

    M.M.J. van der Vorst (Maria); M. Kist (Manfred); A.J. van der Heijden (Bert); J. Burggraaf (Jacobus)

    2006-01-01

    textabstractThis review summarizes current knowledge on the pharmacology, pharmacokinetics, pharmacodynamics, and clinical application of the most commonly used diuretics in children. Diuretics are frequently prescribed drugs in children. Their main indication is to reduce fluid overload in acute an

  16. Current knowledge and attitudes: Russian olive biology, ecology and management

    Science.gov (United States)

    Sharlene E. Sing; Kevin J. Delaney

    2016-01-01

    The primary goals of a two-day Russian olive symposium held in February 2014 were to disseminate current knowledge and identify data gaps regarding Russian olive biology and ecology, distributions, integrated management, and to ascertain the feasibility and acceptance of a proposed program for classical biological control of Russian olive. The symposium was...

  17. Phocine Distemper Virus: Current Knowledge and Future Directions

    Directory of Open Access Journals (Sweden)

    Pádraig J. Duignan

    2014-12-01

    Full Text Available Phocine distemper virus (PDV was first recognized in 1988 following a massive epidemic in harbor and grey seals in north-western Europe. Since then, the epidemiology of infection in North Atlantic and Arctic pinnipeds has been investigated. In the western North Atlantic endemic infection in harp and grey seals predates the European epidemic, with relatively small, localized mortality events occurring primarily in harbor seals. By contrast, PDV seems not to have become established in European harbor seals following the 1988 epidemic and a second event of similar magnitude and extent occurred in 2002. PDV is a distinct species within the Morbillivirus genus with minor sequence variation between outbreaks over time. There is now mounting evidence of PDV-like viruses in the North Pacific/Western Arctic with serological and molecular evidence of infection in pinnipeds and sea otters. However, despite the absence of associated mortality in the region, there is concern that the virus may infect the large Pacific harbor seal and northern elephant seal populations or the endangered Hawaiian monk seals. Here, we review the current state of knowledge on PDV with particular focus on developments in diagnostics, pathogenesis, immune response, vaccine development, phylogenetics and modeling over the past 20 years.

  18. Phocine distemper virus: current knowledge and future directions.

    Science.gov (United States)

    Duignan, Pádraig J; Van Bressem, Marie-Françoise; Baker, Jason D; Barbieri, Michelle; Colegrove, Kathleen M; De Guise, Sylvain; de Swart, Rik L; Di Guardo, Giovanni; Dobson, Andrew; Duprex, W Paul; Early, Greg; Fauquier, Deborah; Goldstein, Tracey; Goodman, Simon J; Grenfell, Bryan; Groch, Kátia R; Gulland, Frances; Hall, Ailsa; Jensen, Brenda A; Lamy, Karina; Matassa, Keith; Mazzariol, Sandro; Morris, Sinead E; Nielsen, Ole; Rotstein, David; Rowles, Teresa K; Saliki, Jeremy T; Siebert, Ursula; Waltzek, Thomas; Wellehan, James F X

    2014-12-22

    Phocine distemper virus (PDV) was first recognized in 1988 following a massive epidemic in harbor and grey seals in north-western Europe. Since then, the epidemiology of infection in North Atlantic and Arctic pinnipeds has been investigated. In the western North Atlantic endemic infection in harp and grey seals predates the European epidemic, with relatively small, localized mortality events occurring primarily in harbor seals. By contrast, PDV seems not to have become established in European harbor seals following the 1988 epidemic and a second event of similar magnitude and extent occurred in 2002. PDV is a distinct species within the Morbillivirus genus with minor sequence variation between outbreaks over time. There is now mounting evidence of PDV-like viruses in the North Pacific/Western Arctic with serological and molecular evidence of infection in pinnipeds and sea otters. However, despite the absence of associated mortality in the region, there is concern that the virus may infect the large Pacific harbor seal and northern elephant seal populations or the endangered Hawaiian monk seals. Here, we review the current state of knowledge on PDV with particular focus on developments in diagnostics, pathogenesis, immune response, vaccine development, phylogenetics and modeling over the past 20 years.

  19. Phocine Distemper Virus: Current Knowledge and Future Directions

    Science.gov (United States)

    Duignan, Pádraig J.; Van Bressem, Marie-Françoise; Baker, Jason D.; Barbieri, Michelle; Colegrove, Kathleen M.; De Guise, Sylvain; de Swart, Rik L.; Di Guardo, Giovanni; Dobson, Andrew; Duprex, W. Paul; Early, Greg; Fauquier, Deborah; Goldstein, Tracey; Goodman, Simon J.; Grenfell, Bryan; Groch, Kátia R.; Gulland, Frances; Hall, Ailsa; Jensen, Brenda A.; Lamy, Karina; Matassa, Keith; Mazzariol, Sandro; Morris, Sinead E.; Nielsen, Ole; Rotstein, David; Rowles, Teresa K.; Saliki, Jeremy T.; Siebert, Ursula; Waltzek, Thomas; Wellehan, James F.X.

    2014-01-01

    Phocine distemper virus (PDV) was first recognized in 1988 following a massive epidemic in harbor and grey seals in north-western Europe. Since then, the epidemiology of infection in North Atlantic and Arctic pinnipeds has been investigated. In the western North Atlantic endemic infection in harp and grey seals predates the European epidemic, with relatively small, localized mortality events occurring primarily in harbor seals. By contrast, PDV seems not to have become established in European harbor seals following the 1988 epidemic and a second event of similar magnitude and extent occurred in 2002. PDV is a distinct species within the Morbillivirus genus with minor sequence variation between outbreaks over time. There is now mounting evidence of PDV-like viruses in the North Pacific/Western Arctic with serological and molecular evidence of infection in pinnipeds and sea otters. However, despite the absence of associated mortality in the region, there is concern that the virus may infect the large Pacific harbor seal and northern elephant seal populations or the endangered Hawaiian monk seals. Here, we review the current state of knowledge on PDV with particular focus on developments in diagnostics, pathogenesis, immune response, vaccine development, phylogenetics and modeling over the past 20 years. PMID:25533658

  20. Conceptual knowledge representation: A cross-section of current research.

    Science.gov (United States)

    Rogers, Timothy T; Wolmetz, Michael

    2016-01-01

    How is conceptual knowledge encoded in the brain? This special issue of Cognitive Neuropsychology takes stock of current efforts to answer this question through a variety of methods and perspectives. Across this work, three questions recur, each fundamental to knowledge representation in the mind and brain. First, what are the elements of conceptual representation? Second, to what extent are conceptual representations embodied in sensory and motor systems? Third, how are conceptual representations shaped by context, especially linguistic context? In this introductory article we provide relevant background on these themes and introduce how they are addressed by our contributing authors.

  1. Detecting misinformation and knowledge conflicts in relational data

    Science.gov (United States)

    Levchuk, Georgiy; Jackobsen, Matthew; Riordan, Brian

    2014-06-01

    Information fusion is required for many mission-critical intelligence analysis tasks. Using knowledge extracted from various sources, including entities, relations, and events, intelligence analysts respond to commander's information requests, integrate facts into summaries about current situations, augment existing knowledge with inferred information, make predictions about the future, and develop action plans. However, information fusion solutions often fail because of conflicting and redundant knowledge contained in multiple sources. Most knowledge conflicts in the past were due to translation errors and reporter bias, and thus could be managed. Current and future intelligence analysis, especially in denied areas, must deal with open source data processing, where there is much greater presence of intentional misinformation. In this paper, we describe a model for detecting conflicts in multi-source textual knowledge. Our model is based on constructing semantic graphs representing patterns of multi-source knowledge conflicts and anomalies, and detecting these conflicts by matching pattern graphs against the data graph constructed using soft co-reference between entities and events in multiple sources. The conflict detection process maintains the uncertainty throughout all phases, providing full traceability and enabling incremental updates of the detection results as new knowledge or modification to previously analyzed information are obtained. Detected conflicts are presented to analysts for further investigation. In the experimental study with SYNCOIN dataset, our algorithms achieved perfect conflict detection in ideal situation (no missing data) while producing 82% recall and 90% precision in realistic noise situation (15% of missing attributes).

  2. Investigation and analysis of the current cognition status of anesthesia-related knowledge for surgical nurses%外科护士对麻醉相关知识认知现状调查与分析

    Institute of Scientific and Technical Information of China (English)

    彭琳; 沈祎蕾; 韩文军

    2016-01-01

    目的 调查并分析某三级甲等医院外科病房护士对麻醉相关知识的掌握情况及其影响因素,为围麻醉期护理管理提供参考. 方法 采用问卷调查法,对上海市某三级甲等综合性医院12个手术科室的护士进行麻醉相关知识调查.调查问卷在文献回顾基础上结合围麻醉期护理常规自行设计,经专家评议和预调查内容效度系数为0.90,信度系数为0.81~0.92.采用整群抽样法,调查所有符合纳入标准的330名护士. 结果 问卷的回收与有效率均为98.18%.324名外科护士对麻醉相关知识的平均得分,折合百分制后为(32±14)分;各维度得分由高至低依次为:麻醉前准备(54±29)分、麻醉后护理要点(31±18)分和基本概念(18±30)分.单因素方差分析显示:学历、职称、年龄、工作年限、科室、是否接受过麻醉课程培训均影响到护士的麻醉相关知识得分且差异有统计学意义(P<0.05);而进一步多元回归分析显示,仅年龄、科室以及是否参加过培训进入回归方程,可解释其总变异的35.6%. 结论 建议依据外科护士所在的科室、年资、培训经历等,有的放矢地实施围麻醉期的理论与技能培训,通过多途径系统化培训提高其对麻醉相关知识的认知水平和参与围麻醉期患者管理的能力,从而确保其能够为围麻醉期患者提供更为安全、专业的预见性护理.%Objective To investigate and analysis of the current cognition status of surgical nurses' anesthesia-related knowledge in a certain hospital at the level of grade Ⅲ class A in Shanghai,and to provide a scientific basis for perianesthesia nursing management.Methods Using questionnaires,330 nurses from 12 surgical departments were investigated with their informed consent.Questionnaire was self-designed based on the literature review combined with the perianesthesia care and the validity is 0.90,reliability is 0.81-0.92.Results Both the questionnaire

  3. Azelaic acid in dermatological treatment – current state of knowledge

    Directory of Open Access Journals (Sweden)

    Radomir Reszke

    2016-09-01

    Full Text Available Azelaic acid (AZA is a naturally occurring substance produced by Malassezia furfur which exerts various effects on the skin. Azelaic acid has antibacterial, anti-inflammatory, keratolytic, comedolytic, sebostatic and tyrosinase-inhibiting properties. Topical application of AZA as 20% cream or 15% gel is a well-established therapeutic method in various common dermatoses, mainly acne vulgaris, rosacea and disorders associated with hyperpigmentation. Azelaic acid is used as a component of chemical peels as well. The paper summarizes the most relevant issues concerning AZA application in dermatological treatment based on current knowledge.

  4. Nausea: current knowledge of mechanisms, measurement and clinical impact.

    Science.gov (United States)

    Kenward, Hannah; Pelligand, Ludovic; Savary-Bataille, Karine; Elliott, Jonathan

    2015-01-01

    Nausea is a subjective sensation, which often acts as a signal that emesis is imminent. It is a widespread problem that occurs as a clinical sign of disease or as an adverse effect of a drug therapy or surgical procedure. The mechanisms of nausea are complex and the neural pathways are currently poorly understood. This review summarises the current knowledge of nausea mechanisms, the available animal models for nausea research and the anti-nausea properties of commercially available anti-emetic drugs. The review also presents subjective assessment and scoring of nausea. A better understanding of the underlying mechanisms of nausea might reveal potential clinically useful biomarkers for objective measurement of nausea in species of veterinary interest.

  5. [In the light of current knowledge right ventricle].

    Science.gov (United States)

    Taçoy, Gülten; Cengel, Atiye

    2014-09-01

    There are important differences between left and right ventricle. Due to anatomical location and structural features, in daily clinical practice the right ventricle cannot be assessed easily as the left ventricle. Therefore, the right ventricle has remained in the background of the left ventricle. Recent clinical studies and advanced imaging modalities have demonstrated that right ventricle is decisive for survival particularly in patients with congenital heart disease, pulmonary hypertension and heart failure. Therefore, the detailed evaluation of the right ventricle has become necessary in current clinical practice. For this reason, in our review we aimed to examine the embryological development, anatomical structure, physiological, metabolic characteristics, responses to different pathological conditions, effects on arrhythmias, causes of failure and imaging modalities of the right ventricle in light of the current knowledge's.

  6. Current knowledge, gaps and challenges in the Southern European Seas

    Science.gov (United States)

    Papathanassiou, Evangelos

    2015-04-01

    New knowledge advances our current understanding on the selection and application of the appropriate tools for assessing the state of the marine environment in the Southern European Seas (SES). Diminishing the lack of knowledge is a prerequisite for sound policy decisions. Although gaps and knowledge are fewer today, the health of marine and coastal ecosystems in the SES is under pressure and shows, in places, some signs of deterioration and declining quality. Overall, there is a lack of data accessibility and long time series in the SES, while in many cases poorly constrained processes cannot really support knowledge-based policy making (e.g. ecosystem functioning, climate change, fisheries management, etc.). New knowledge has to be produced and excellence must be promoted to support sustainable economic growth. At the same time, existing and new capacities have to be upgraded and increased in order to support sustainable convergence between SES countries. There are several gaps that have been identified and processes that have been poorly understood in the SES, mainly from research projects that have been working at basin level. The main research priorities that have been identified from the SeasERA Project for both, the Mediterranean and the Black Sea include: the climate change and its impacts, the hydrological cycle, the ventilation and the inter-basin coupling, the marine biodiversity and the provision of goods and services, the marine protected areas, the deep sea ecosystems, the biological invasions, the marine pollution and the ocean and human health, the renewable energy, the maritime transport, the fisheries and aquaculture activities and the biotechnology and the exploitation of marine resources for industrial application. More important, however, is the fact that the economic, the social and the scientific and the environmental challenges must be collectively tackled. They should have prioritisation and clear objectives as well as data sharing for

  7. Knowledge related activities in open innovation

    DEFF Research Database (Denmark)

    Pedrosa, Alex; Välling, Margus; Boyd, Britta

    2013-01-01

    Theory and practice both have recognised the importance of external knowledge to enhance organisations’ innovation performance. Due to organisations’ growing interest in effectively collaborating with external knowledge sources, research has investigated the importance of firm-external stakeholder...... interaction in open innovation. Despite valuable insights into the importance of the variety of external knowledge sources to enhance (open) innovation, research has overlooked so far that managers’ characteristics and practices are relevant for the absorption of external knowledge in open innovation. Thus...... organisations. Our findings show that the exploration, transformation, and exploitation of external knowledge are associated with a distinct set of managers’ characteristics and practices that capture the dominant pattern of processing external knowledge in open innovation....

  8. Cyanobactins from Cyanobacteria: Current Genetic and Chemical State of Knowledge

    Directory of Open Access Journals (Sweden)

    Joana Martins

    2015-11-01

    Full Text Available Cyanobacteria are considered to be one of the most promising sources of new, natural products. Apart from non-ribosomal peptides and polyketides, ribosomally synthesized and post-translationally modified peptides (RiPPs are one of the leading groups of bioactive compounds produced by cyanobacteria. Among these, cyanobactins have sparked attention due to their interesting bioactivities and for their potential to be prospective candidates in the development of drugs. It is assumed that the primary source of cyanobactins is cyanobacteria, although these compounds have also been isolated from marine animals such as ascidians, sponges and mollusks. The aim of this review is to update the current knowledge of cyanobactins, recognized as being produced by cyanobacteria, and to emphasize their genetic clusters and chemical structures as well as their bioactivities, ecological roles and biotechnological potential.

  9. Cyanobactins from Cyanobacteria: Current Genetic and Chemical State of Knowledge.

    Science.gov (United States)

    Martins, Joana; Vasconcelos, Vitor

    2015-11-13

    Cyanobacteria are considered to be one of the most promising sources of new, natural products. Apart from non-ribosomal peptides and polyketides, ribosomally synthesized and post-translationally modified peptides (RiPPs) are one of the leading groups of bioactive compounds produced by cyanobacteria. Among these, cyanobactins have sparked attention due to their interesting bioactivities and for their potential to be prospective candidates in the development of drugs. It is assumed that the primary source of cyanobactins is cyanobacteria, although these compounds have also been isolated from marine animals such as ascidians, sponges and mollusks. The aim of this review is to update the current knowledge of cyanobactins, recognized as being produced by cyanobacteria, and to emphasize their genetic clusters and chemical structures as well as their bioactivities, ecological roles and biotechnological potential.

  10. The physiological ecology of vascular epiphytes: current knowledge, open questions.

    Science.gov (United States)

    Zotz, G; Hietz, P

    2001-11-01

    The current knowledge of the physiological ecology of vascular epiphytes is reviewed here with an emphasis on the most recent literature. It is argued that by far the most relevant abiotic constraint for growth and vegetative function of vascular epiphytes is water shortage, while other factors such as nutrient availability or irradiation, are generally of inferior importance. However, it is shown that the present understanding of epiphyte biology is still highly biased, both taxonomically and ecologically, and it is concluded that any generalizations are still preliminary. Future studies should include a much wider range of taxa and growing sites within the canopy to reach a better understanding how abiotic factors are limiting epiphyte growth and survival which, in turn, should affect epiphyte community composition. Finally, a more integrative approach to epiphyte biology is encouraged: physiological investigations should be balanced by studies of other possible constraints, for example, substrate instability, dispersal limitation, competition or herbivory.

  11. Relational knowledge leadership and local economic development

    NARCIS (Netherlands)

    Horlings, Lummina; Collinge, Chris; Gibney, John

    2017-01-01

    This paper concerns the role of spatial leadership in the development of the knowledge-based economy. It is argued within academic and practitioner circles that leadership of knowledge networks requires a particular non-hierarchical style that is required to establish an ambience conducive to

  12. Relational knowledge leadership and local economic development

    NARCIS (Netherlands)

    Horlings, Lummina; Collinge, Chris; Gibney, John

    2017-01-01

    This paper concerns the role of spatial leadership in the development of the knowledge-based economy. It is argued within academic and practitioner circles that leadership of knowledge networks requires a particular non-hierarchical style that is required to establish an ambience conducive to networ

  13. A VIEWPOINT ON THE CURRENT STATE OF KNOWLEDGE MANAGEMENT INSTRUMENTS

    OpenAIRE

    ANDREEA PAULA DUMITRU

    2011-01-01

    Knowledge management is seeking solutions to harmonize the objectives of organizations of the human group, which need to rationalize, to provide policy makers and to implement. This article aims to provide readers with an introduction to knowledge management basic definitions, theories and concepts such as types of knowledge, the differences between data, information and knowledge, etc, are given. But, why we need a knowledge management ? This article justified the need for companies to focus...

  14. Brown carbon in the cryosphere: Current knowledge and perspective

    Directory of Open Access Journals (Sweden)

    Guang-Ming Wu

    2016-03-01

    Full Text Available Recently, the light-absorbing organic carbon, i.e., brown carbon (BrC, has received an increasing attention, because they could significantly absorb the solar radiation in the range of short wavelengths rather than the purely scattering effect. BrC is ubiquitous in the troposphere. It could undergo long range transport within the atmospheric circulation. After the deposition on the surface of snow or ice in the cryospheric region, as the major light absorbing impurities with black carbon and dust, BrC could reduce the snow albedo and accelerate the glacier melting. In this context, this paper summarized the current knowledge of BrC (in aerosols and snow in the cryospheric regions including the Arctic, Antarctic, and Alpines. Although some works have been conducted in those region, the current dataset on the optical properties of BrC like Absorption Ångström Exponent (AAE and Mass Absorption Efficiency (MAE is still limited, which hampers stimulating an accurate evaluation of its climate effects. Especially in the Himalayas and Tibetan Plateau, where very limited information concerning BrC is available. Considering biomass burning as a dominant source of BrC, a large amount of emissions from biomass burning in South Asia could reach the Himalayas and Tibetan Plateau, where the climate effect of BrC merits more investigation in the future.

  15. HIV and AIDS-related knowledge among women in Iraq

    Directory of Open Access Journals (Sweden)

    Rudatsikira Emmanuel

    2008-12-01

    Full Text Available Abstract Background Individuals who are aware of the risk of infection and perceive themselves to be at risk of infection are more likely to take action to prevent HIV infection. The aim of this study was to assess the knowledge of HIV/AIDS among Iraqi women. Methods A secondary analysis of the 2000 Multiple Cluster Indicator Survey (MICS for Iraq was carried out to assess the extent of HIV/AIDS-related knowledge among Iraqi women. Results The majority of the 22,997 respondents were age 15–24 years (44.3%, currently married (51.4%, and resided in urban areas (71.7%. About 1 in 4 (26.0% of the study participants had no formal education. Only 49.9% had heard of HIV/AIDS. Overall, 60.5% did not know that HIV can be transmitted through blood transfusion. Meanwhile, 98.5% of the respondents did not know that HIV can be transmitted from mother to child through breast milk. Only 0.7% of the respondents reported that HIV cannot be transmitted through mosquito bites. The proportion of the respondents who had adequate knowledge on HIV/AIDS was 9.8%. Adequate knowledge of HIV/AIDS was negatively associated with being married, poor, having low education, and residing in rural areas. Conclusion Findings from this study indicate that adequate knowledge of HIV/AIDS among Iraqi is very limited and associated with marital status, education, wealth, and place of residence. This information may be of use in the design, targeting, monitoring and evaluation of programs aimed at improving HIV and AIDS related knowledge in Iraq.

  16. A VIEWPOINT ON THE CURRENT STATE OF KNOWLEDGE MANAGEMENT INSTRUMENTS

    Directory of Open Access Journals (Sweden)

    ANDREEA PAULA DUMITRU

    2011-04-01

    Full Text Available Knowledge management is seeking solutions to harmonize the objectives of organizations of the human group, which need to rationalize, to provide policy makers and to implement. This article aims to provide readers with an introduction to knowledge management basic definitions, theories and concepts such as types of knowledge, the differences between data, information and knowledge, etc, are given. But, why we need a knowledge management ? This article justified the need for companies to focus management efforts on their intangible elements and provides the five enabling conditions for knowledge creation.

  17. Cardiovascular pharmacogenomics; state of current knowledge and implementation in practice.

    Science.gov (United States)

    Shahabi, Payman; Dubé, Marie-Pierre

    2015-04-01

    Pharmacogenomics (PGx) is the science that examines how an individual's genetic make-up affects the safety and efficacy of therapeutic drugs. PGx of response to cardiovascular (CV) medications is of the most successfully translated branches of PGx into the clinical workout. However, the clinical implementation of PGx of CV drugs is yet far beyond the growth of our understanding of the role of genetics in drug therapy. A considerable amount of efforts have been devoted by the regulatory agents like the food and drug administration (FDA) as well as the expert-based networks such as the Clinical Pharmacogenetics Implementation Consortium (CPIC) to overcome the existing barriers. This has been done, at least in part, for some of the most widely prescribed CV drugs, including clopidogrel, warfarin and simvastatin for which the PGx knowledge have been satisfactorily robust to provoke the CPIC to issue the guidelines for these drugs and the FDA to update the drugs' labeling, both strongly recommended the use of genotype-guided dosing for these medications, provided that the genetic data are available. For other drugs, however, studies have produced contradictory results and further large and well-designed clinical trials are required to expand and confirm the clinical utility of their PGx data. This review paper presents the current state of knowledge in the field of PGx of CV medications and describes the facilities assisting to the translation of PGx data into the clinical practice. Afterward, the existing body of PGx literature of the most-commonly used CV medications is comprehensively discussed.

  18. Current Usage of Relative Pronouns in Spanish.

    Science.gov (United States)

    Ozete, Oscar

    1981-01-01

    Examines variations in current usage that pose problems in teaching Spanish relative pronouns. Discusses their treatment in first-year college textbooks, in the professional literature and in newspapers and magazines prose. Attempts to provide a description of the use of these pronouns applicable to classroom presentation. (MES)

  19. Climate change and respiratory health: current evidence and knowledge gaps.

    Science.gov (United States)

    Takaro, Tim K; Knowlton, Kim; Balmes, John R

    2013-08-01

    Climate change is a key driver of the accelerating environmental change affecting populations around the world. Many of these changes and our response to them can affect respiratory health. This is an expert opinion review of recent peer-reviewed literature, focused on more recent medical journals and climate-health relevant modeling results from non-biomedical journals pertaining to climate interactions with air pollution. Global health impacts in low resource countries and migration precipitated by environmental change are addressed. The major findings are of respiratory health effects related to heat, air pollution, shifts in infectious diseases and allergens, flooding, water, food security and migration. The review concludes with knowledge gaps and research need that will support the evidence-base required to address the challenges ahead.

  20. Current expertise location by exploiting the dynamics of knowledge

    Directory of Open Access Journals (Sweden)

    Josef Nozicka

    2012-10-01

    Full Text Available Systems for expertise location are either very expensive in terms of the costs of maintenance or they tend to become obsolete or incomplete during the time. This article presents a new approach to knowledge mapping/expertise location allowing reducing the costs of knowledge mapping by maintaining the accuracy of the knowledge map. The efficiency of the knowledge map is achieved by introducing the knowledge estimation measures analysing the dynamics of knowledge of company employees and their textual results of work. Finding an expert with most up-to date knowledge is supported by focusing publishing history analysis. The efficiency of proposed measures within various timeframes of publishing history is evaluated by evaluation method introduced within the article. The evaluation took place in the environment of a middle-sized software company allowing seeing directly a practical usability of the expertise location technique. The results form various implications deployment of knowledge map within the company.

  1. Understanding the Climate-knowledge Sharing Relation

    DEFF Research Database (Denmark)

    Llopis, Oscar; Foss, Nicolai Juul

    2016-01-01

    motivation and job autonomy as moderators of this relationship. We find that the social climate for cooperation better predicts knowledge sharing when employees show low levels of intrinsic motivation and have high levels of job autonomy. This suggests that a cooperative climate and intrinsic motivation......A cooperative organizational climate is often argued to promote knowledge-sharing behaviors among employees. However, research indicates that managerial interventions aimed at shaping the organizational climate can be difficult to execute. We develop and test a contingency model of intrinsic...

  2. School Management Related Knowledge Levels of Primary School Teachers

    Science.gov (United States)

    Ugurlu, Celal Teyyar

    2013-01-01

    The knowledge levels of the teachers affect the qualifications of operations and transactions in schools. School management related knowledge of the teachers is an essential tool to reach the targets of the school. The objective of this study was to determine the school management related knowledge levels of the teachers. Qualitative and…

  3. Animal Related Activities as Determinants of Species Knowledge

    Science.gov (United States)

    Randler, Christoph

    2010-01-01

    Previous work has established a relationship between knowledge and environmental concern. Different factors may contribute to this knowledge and animal-related leisure activities may also contribute to this knowledge. 390 participants in Leipzig, Germany were interviewed to assess their animal-related leisure activities, their demographic status…

  4. Microorganisms in Fermented Apple Beverages: Current Knowledge and Future Directions.

    Science.gov (United States)

    Cousin, Fabien J; Le Guellec, Rozenn; Schlusselhuber, Margot; Dalmasso, Marion; Laplace, Jean-Marie; Cretenet, Marina

    2017-07-25

    Production of fermented apple beverages is spread all around the world with specificities in each country. 'French ciders' refer to fermented apple juice mainly produced in the northwest of France and often associated with short periods of consumption. Research articles on this kind of product are scarce compared to wine, especially on phenomena associated with microbial activities. The wine fermentation microbiome and its dynamics, organoleptic improvement for healthy and pleasant products and development of starters are now widely studied. Even if both beverages seem close in terms of microbiome and process (with both alcoholic and malolactic fermentations), the inherent properties of the raw materials and different production and environmental parameters make research on the specificities of apple fermentation beverages worthwhile. This review summarizes current knowledge on the cider microbial ecosystem, associated activities and the influence of process parameters. In addition, available data on cider quality and safety is reviewed. Finally, we focus on the future role of lactic acid bacteria and yeasts in the development of even better or new beverages made from apples.

  5. Current status of knowledge on public-speaking anxiety.

    Science.gov (United States)

    Pull, Charles B

    2012-01-01

    This review examines the current knowledge on public-speaking anxiety, that is, the fear of speaking in front of others. This article summarizes the findings from previous review articles and describes new research findings on basic science aspects, prevalence rates, classification, and treatment that have been published between August 2008 and August 2011. Recent findings highlight the major aspects of psychological and physiological reactivity to public speaking in individuals who are afraid to speak in front of others, confirm high prevalence rates of the disorder, contribute to identifying the disorder as a possibly distinct subtype of social anxiety disorder (SAD), and give support to the efficacy of treatment programs using virtual reality exposure and Internet-based self-help. Public-speaking anxiety is a highly prevalent disorder, leading to excessive psychological and physiological reactivity. It is present in a majority of individuals with SAD and there is substantial evidence that it may be a distinct subtype of SAD. It is amenable to treatment including, in particular, new technologies such as exposure to virtual environments and the use of cognitive-behavioral self-help programs delivered on the Internet.

  6. Current Approaches Regarding the Knowledge Management Impact on SMEs Performance

    Directory of Open Access Journals (Sweden)

    Ionela Carmen RIZEA (PIRNEA

    2011-12-01

    Full Text Available Managing knowledge is a critical capability for small to medium-sized enterprises (SMEs to master because it helps them leverage their most critical resource. Organizational knowledge is the most salient resource at the disposal of SMEs in terms of availability, access, and depth. Successful SMEs are those who can leverage their knowledge in an effective and efficient manner, so as to make up for deficiencies in traditional resources, like land, labor, and capital. The purpose of this article is to identify the knowledge management impact on SMEs performance and to compare knowledge management in SMEs with knowledge management in large companies. The research discovered that SMEs do not manage knowledge the same way as larger organizations.

  7. Relational capital, new knowledge and innovative ideas

    NARCIS (Netherlands)

    T.J.M. Mom (Tom)

    2016-01-01

    markdownabstractOrganisational learning occurs when people engage in exploration activities – activities aimed at acquiring and using new knowledge, ideas and insights. Exploration, explains Tom Mom, associate professor of strategic entrepreneurship at RSM, ‘is about people and organisations promoti

  8. Logical knowledge representation of regulatory relations in biomedical pathways

    DEFF Research Database (Denmark)

    Zambach, Sine; Hansen, Jens Ulrik

    2010-01-01

    Knowledge on regulatory relations, in for example regulatory pathways in biology, is used widely in experiment design by biomedical researchers and in systems biology. The knowledge has typically either been represented through simple graphs or through very expressive differential equation...

  9. Logical knowledge representation of regulatory relations in biomedical pathways

    DEFF Research Database (Denmark)

    Zambach, Sine; Hansen, Jens Ulrik

    2010-01-01

    Knowledge on regulatory relations, in for example regulatory pathways in biology, is used widely in experiment design by biomedical researchers and in systems biology. The knowledge has typically either been represented through simple graphs or through very expressive differential equation...

  10. Oxytocin and Socioemotional Aging─Current Knowledge and Future Trends

    Directory of Open Access Journals (Sweden)

    Natalie C. Ebner

    2013-08-01

    Full Text Available The oxytocin (OT system is involved in various aspects of social cognition and prosocial behavior. Specifically, OT has been examined in the context of social memory, emotion recognition, cooperation, trust, empathy, and bonding, and─though evidence is somewhat mixed─intranasal OT appears to benefit aspects of socioemotional functioning. However, most of the extant data on aging and OT is from animal research and human OT research has focused largely on young adults. As such, though we know that various socioemotional capacities change with age, we know little about whether age-related changes in the OT system may underlie age-related differences in socioemotional functioning. In this review, we take a genetic-neuro-behavioral approach and evaluate current evidence on age-related changes in the OT system as well as the putative effects of these alterations on age-related socioemotional functioning. Looking forward, we identify informational gaps and propose an Age-Related Genetic, Neurobiological, Sociobehavioral Model of Oxytocin (AGeNeS-OT model which may structure and inform investigations into aging-related genetic, neural, and sociocognitive processes related to OT. As an exemplar of the use of the model, we report exploratory data suggesting differences in socioemotional processing associated with genetic variation in the oxytocin receptor gene (OXTR in samples of young and older adults. Information gained from this arena has translational potential in depression, social stress, and anxiety─all of which have high relevance in aging─and may contribute to reducing social isolation and improving well-being of individuals across the lifespan.

  11. 46 CFR 11.713 - Requirements for maintaining current knowledge of waters to be navigated.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Requirements for maintaining current knowledge of waters... § 11.713 Requirements for maintaining current knowledge of waters to be navigated. (a) If a first class... current knowledge of the route. Persons using this method of re-familiarization shall certify,...

  12. Prophylaxis and therapeutic potential of ozone in buiatrics: Current knowledge.

    Science.gov (United States)

    Đuričić, Dražen; Valpotić, Hrvoje; Samardžija, Marko

    2015-08-01

    Ozone therapy has been in use since 1896 in the USA. As a highly reactive molecule, ozone may inactivate bacteria, viruses, fungi, yeasts and protozoans, stimulate the oxygen metabolism of tissue, treat diseases, activate the immune system, and exhibit strong analgesic activity. More recently, ozone has been used in veterinary medicine, particularly in buiatrics, but still insufficiently. Medical ozone therapy has shown effectiveness as an alternative to the use of antibiotics, which are restricted to clinical use and have been withdrawn from non-clinical use as in-feed growth promoters in animal production. This review is an overview of current knowledge regarding the preventive and therapeutic effects of ozone in ruminants for the treatment of puerperal diseases and improvement in their fertility. In particular, ozone preparations have been tested in the treatment of reproductive tract lesions, urovagina and pneumomovagina, metritis, endometritis, fetal membrane retention and mastitis, as well as in the functional restoration of endometrium in dairy cows and goats. In addition, the preventive use of the intrauterine application of ozone has been assessed in order to evaluate its effectiveness in improving reproductive efficiency in dairy cows. No adverse effects were observed in cows and goats treated with ozone preparations. Moreover, there is a lot of evidence indicating the advantages of ozone preparation therapy in comparison to the application of antibiotics. However, there are certain limitations on ozone use in veterinary medicine and buiatrics, such as inactivity against intracellular microbes and selective activity against the same bacterial species, as well as the induction of tissue inflammation through inappropriate application of the preparation.

  13. Current problems in Russian-Latvian relations

    Directory of Open Access Journals (Sweden)

    Mezhevich Nikolay

    2013-09-01

    Full Text Available Current relations between Russia and Latvia are still influenced by a series of mutual claims that appeared after the demise of the USSR. Latvia — as well as Estonia and Lithuania — is both an EU and NATO member state. However, unlike the above mentioned countries, its relations with Russia are developing at a more pragmatic level. Numerous political differences often result in economic losses both for Latvia and Russia. Despite the fact that Latvia has been an independent state for more than 20 years, there are still some unresolved issues in its relations with Russia. Today, relations between the two countries are often viewed through the prism of EU — Russia relations. Nonetheless, they often do not fit this context. Settling differences between Latvia and Russia will contribute to trade relations, which are increasingly important for both parties. In order to prevent and localise emerging conflicts, diplomats, politicians, and experts should interpret Russian-Latvian relations in view of the national features without referring to theoretical models based on the mythological “unity” of the three Baltic States.

  14. Current state of knowledge about nutritional care of pregnant women

    Directory of Open Access Journals (Sweden)

    Luciana Barretto

    2014-12-01

    Full Text Available Pregnancy involves a significant anabolic activity that leads to increased nutritional needs relative to the preconception period. This paper aims to review the current understanding of the energy needs of macro and micronutrients during pregnancy as well as guidelines to address common gastrointestinal disorders during pregnancy, the issue of pica and anthropometric assessment to ensure an optimum weight gain. With the exception of iron, most of the nutrients needed by the pregnancy can be provided by a complete and balanced diet. Currently the scientific evidence shows that routine supplementation with iron and folic acid during pregnancy is a practice that prevents iron deficiency anemia, neural tube disorders and preterm births. Intermittent iron supplementation can also be an appropriated intervention. If the diet does not guarantee and adequate support, iodine, vitamin B12 and vitamin D supplements should also be necessaries. The anthropometric assessment by the pattern of weight gain should be present at each prenatal care visit to prevent maternal and fetal complications. In situations where the mother’s weight cannot be assessed, arm muscle circumference is possible to make an overall assessment as it correlates with maternal weight gain alternative. Measurements of biceps, triceps and subscapular skinfolds are another alternative that is useful to evaluate the fatty deposits and their location, in a complementary way to gain weight.

  15. STR allele sequence variation: Current knowledge and future issues.

    Science.gov (United States)

    Gettings, Katherine Butler; Aponte, Rachel A; Vallone, Peter M; Butler, John M

    2015-09-01

    This article reviews what is currently known about short tandem repeat (STR) allelic sequence variation in and around the twenty-four loci most commonly used throughout the world to perform forensic DNA investigations. These STR loci include D1S1656, TPOX, D2S441, D2S1338, D3S1358, FGA, CSF1PO, D5S818, SE33, D6S1043, D7S820, D8S1179, D10S1248, TH01, vWA, D12S391, D13S317, Penta E, D16S539, D18S51, D19S433, D21S11, Penta D, and D22S1045. All known reported variant alleles are compiled along with genomic information available from GenBank, dbSNP, and the 1000 Genomes Project. Supplementary files are included which provide annotated reference sequences for each STR locus, characterize genomic variation around the STR repeat region, and compare alleles present in currently available STR kit allelic ladders. Looking to the future, STR allele nomenclature options are discussed as they relate to next generation sequencing efforts underway.

  16. Tracing Error-Related Knowledge in Interview Data: Negative Knowledge in Elder Care Nursing

    Science.gov (United States)

    Gartmeier, Martin; Gruber, Hans; Heid, Helmut

    2010-01-01

    This paper empirically investigates elder care nurses' negative knowledge. This form of experiential knowledge is defined as the outcome of error-related learning processes, focused on how something is not, on what not to do in certain situations or on deficits in one's knowledge or skills. Besides this definition, we presume the existence of…

  17. Integrating Relational Reasoning and Knowledge Revision during Reading

    Science.gov (United States)

    Kendeou, Panayiota; Butterfuss, Reese; Van Boekel, Martin; O'Brien, Edward J.

    2017-01-01

    Our goal in this theoretical contribution is to connect research on knowledge revision and relational reasoning. To achieve this goal, first, we review the "knowledge revision components framework" (KReC) that provides an account of knowledge revision processes, specifically as they unfold during reading of texts. Second, we review a…

  18. Background Knowledge in Learning-Based Relation Extraction

    Science.gov (United States)

    Do, Quang Xuan

    2012-01-01

    In this thesis, we study the importance of background knowledge in relation extraction systems. We not only demonstrate the benefits of leveraging background knowledge to improve the systems' performance but also propose a principled framework that allows one to effectively incorporate knowledge into statistical machine learning models for…

  19. Background Knowledge in Learning-Based Relation Extraction

    Science.gov (United States)

    Do, Quang Xuan

    2012-01-01

    In this thesis, we study the importance of background knowledge in relation extraction systems. We not only demonstrate the benefits of leveraging background knowledge to improve the systems' performance but also propose a principled framework that allows one to effectively incorporate knowledge into statistical machine learning models for…

  20. Knowledge and barriers relating to fish consumption in older Australians.

    Science.gov (United States)

    Grieger, Jessica A; Miller, Michelle; Cobiac, Lynne

    2012-10-01

    Among 854 Australians ≥ 51 years of age, this cross-sectional survey explored knowledge regarding finfish consumption, sources of information on fish and omega 3 fatty acids, what barriers limit finfish consumption and what factors predict its consumption. The survey consisted of a validated quantitative fish frequency questionnaire with additional questions on barriers and knowledge relating to finfish. Twelve percent of respondents consumed oily fish ≥ 2 times per week. Cost was the most frequently (37%) reported barrier for fresh finfish consumption. In multiple regression analysis, respondents' exposure to multiple sources of information (odds ratio (95% confidence interval): 1.135 (1.01, 1.28), who correctly identified the current recommendations for fish consumption; 1.87 (1.13, 3.07), agreed that fish improves general health; 3.57 (1.13, 11.30), and reported fewer barriers towards canned fish consumption; 0.59 (0.41, 0.84) were more likely to consume ≥ 2 servings of fresh finfish per week. Education and health programs need to be readily available highlighting current recommendations for fish consumption and how targets can be achieved. Meal plans with various finfish/seafood and amounts of omega 3 fatty acids required to achieve recommendations, and within a suitable budget, is likely to be an important strategy to target older consumers to increase consumption.

  1. The functional neuroanatomy of thematic role and locative relational knowledge.

    Science.gov (United States)

    Wu, Denise H; Waller, Sara; Chatterjee, Anjan

    2007-09-01

    Lexical-semantic investigations in cognitive neuroscience have focused on conceptual knowledge of concrete objects. By contrast, relational concepts have been largely ignored. We examined thematic role and locative knowledge in 14 left-hemisphere-damage patients. Relational concepts shift cognitive focus away from the object to the relationship between objects, calling into question the relevance of traditional sensory-functional accounts of semantics. If extraction of a relational structure is the critical cognitive process common to both thematic and locative knowledge, then damage to neural structures involved in such an extraction would impair both kinds of knowledge. If the nature of the relationship itself is critical, then functional neuroanatomical dissociations should occur. Using a new lesion analysis method, we found that damage to the lateral temporal cortex produced deficits in thematic role knowledge and damage to inferior fronto-parietal regions produced deficits in locative knowledge. In addition, we found that conceptual knowledge of thematic roles dissociates from its mapping onto language. These relational knowledge deficits were not accounted for by deficits in processing nouns or verbs or by a general deficit in making inferences. Our results are consistent with the hypothesis that manners of visual motion serve as a point of entry for thematic role knowledge and networks dedicated to eye gaze, whereas reaching and grasping serve as a point of entry for locative knowledge. Intermediary convergence zones that are topographically guided by these sensory-motor points of entry play a critical role in the semantics of relational concepts.

  2. Febrile Seizures and Febrile Seizure Syndromes: An Updated Overview of Old and Current Knowledge.

    Science.gov (United States)

    Khair, Abdulhafeez M; Elmagrabi, Dalal

    2015-01-01

    Febrile seizures are the most common paroxysmal episode during childhood, affecting up to one in 10 children. They are a major cause of emergency facility visits and a source of family distress and anxiety. Their etiology and pathophysiological pathways are being understood better over time; however, there is still more to learn. Genetic predisposition is thought to be a major contributor. Febrile seizures have been historically classified as benign; however, many emerging febrile seizure syndromes behave differently. The way in which human knowledge has evolved over the years in regard to febrile seizures has not been dealt with in depth in the current literature, up to our current knowledge. This review serves as a documentary of how scientists have explored febrile seizures, elaborating on the journey of knowledge as far as etiology, clinical features, approach, and treatment strategies are concerned. Although this review cannot cover all clinical aspects related to febrile seizures at the textbook level, we believe it can function as a quick summary of the past and current sources of knowledge for all varieties of febrile seizure types and syndromes.

  3. Pain in Neurodegenerative Disease: Current Knowledge and Future Perspectives

    Directory of Open Access Journals (Sweden)

    Marina de Tommaso

    2016-01-01

    Full Text Available Neurodegenerative diseases are going to increase as the life expectancy is getting longer. The management of neurodegenerative diseases such as Alzheimer’s disease (AD and other dementias, Parkinson’s disease (PD and PD related disorders, motor neuron diseases (MND, Huntington’s disease (HD, spinocerebellar ataxia (SCA, and spinal muscular atrophy (SMA, is mainly addressed to motor and cognitive impairment, with special care to vital functions as breathing and feeding. Many of these patients complain of painful symptoms though their origin is variable, and their presence is frequently not considered in the treatment guidelines, leaving their management to the decision of the clinicians alone. However, studies focusing on pain frequency in such disorders suggest a high prevalence of pain in selected populations from 38 to 75% in AD, 40% to 86% in PD, and 19 to 85% in MND. The methods of pain assessment vary between studies so the type of pain has been rarely reported. However, a prevalent nonneuropathic origin of pain emerged for MND and PD. In AD, no data on pain features are available. No controlled therapeutic trials and guidelines are currently available. Given the relevance of pain in neurodegenerative disorders, the comprehensive understanding of mechanisms and predisposing factors, the application and validation of specific scales, and new specific therapeutic trials are needed.

  4. [Work related stress: from knowledge to practice].

    Science.gov (United States)

    Costa, G

    2009-01-01

    Work-related stress is a well documented condition, resulting from a distorted interaction between working conditions and individual coping resources, that may have a negative impact on workers' health and well-being, as well as nd on performance efficiency and productivity: hence high costs for workers companies and society. It is a complex multifaceted and multidimensional phenomenon, whose assessment needs a multidisciplinary approach (work management, psychology, physiology, ergonomics, sociology, medicine). That is why risk assessment and management require a careful analysis of work organization (i.e. working time, work load, autonomy, environment, human relations) and individual aspects (i.e. demography, personality, attitudes, motivation, coping strategies). The consequent actions, targeted to the individuals, groups and organizations, should be aimed at preventing or reducing work-related stress, on the one hand, and supporting and protecting the worker, on the other, considering cost/effectiveness and risk/benefit ratios. This can be achieveds to be done with the participation and close collaboration of all the social actors involved (employers, employees, technicians, work organization and occupational health experts), according to the European Framework Agreement on Work-related Stress, signed on October 2004 and included into the Italian Law Decree 81/2008.

  5. Knowledge visualization currents from text to art to culture

    CERN Document Server

    Marchese, Francis T

    2012-01-01

    Presents the state of the art in visualization research and development Highlights research developing at key intersections with other disciplines and its applicability to addressing complex real-world problems Discusses how visualization researchers are addressing complex issues of representation in knowledge, art, and culture

  6. Modelling Knowledge Systems using Relation Nets and Hypernets

    OpenAIRE

    Rooyen, Hendrik O. van; Geldenhuys, Aletta E.; Stetter, Franz

    2004-01-01

    In the book "Knowledge Representation and Relation Nets" we introduced a structural model called a Relation Net and a special relation net called a Concept Relationship Knowledge Structure (CRKS). In this work we broaden the notion of a relation net to produce a new but associated structural model, a Hypernet. We show that the general theory of hypernets has applications in the acquisition/learning, representation, retrieval, accommodation and assimilation, management and communication/teachi...

  7. YBCO SQUIDs with unconventional current phase relation

    Energy Technology Data Exchange (ETDEWEB)

    Bauch, T. [Quantum Device Physics Laboratory, Department of Microtechnology and Nanoscience, MC2, Chalmers University of Technology, SE-41296 Goeteborg (Sweden)], E-mail: Thilo.bauch@mc2.chalmers.se; Johansson, J.; Cedergren, K. [Quantum Device Physics Laboratory, Department of Microtechnology and Nanoscience, MC2, Chalmers University of Technology, SE-41296 Goeteborg (Sweden); Lindstroem, T. [National Physical Laboratory, Teddington, Middlesex TW11 0LW (United Kingdom); Lombardi, F. [Quantum Device Physics Laboratory, Department of Microtechnology and Nanoscience, MC2, Chalmers University of Technology, SE-41296 Goeteborg (Sweden)

    2007-10-01

    We have studied the dynamics of YBa{sub 2}Cu{sub 3}O{sub 7-{delta}} (YBCO) dc sperconducting quantum interference devices (SQUIDs) characterized by an unconventional Josephson current phase relation (CPR). We have focused on SQUID configurations with Josephson junctions where the lobe of the order parameter in one electrode is facing a node in the other electrode. This order parameter arrangement should enhance the appearance of a sin(2{phi}) term in the CPR. The response of the critical current of the dc SQUID, under the effect of an external magnetic field, has been measured in temperature, down to 20 mK. Our experimental data have been compared with numerical simulations of the SQUIDs dynamics by considering a CPR of a single junction of the form I({phi}) = I{sup I} sin({phi}) - I{sup II} sin(2{phi}) where I{sup I} and I{sup II} are, respectively, the first and second harmonic component. In our devices the values of the sin(2{phi}) term are such that the fundamental state of the SQUID is naturally double degenerate. This is of great relevance for applications of d-wave SQUIDs in quantum information processing.

  8. (Dysfunctional relations between knowledge quality and education system

    Directory of Open Access Journals (Sweden)

    Avramović Zoran

    2011-01-01

    Full Text Available Functional analysis of the relation between knowledge and education system from the viewpoint of quality is used in the paper. It is proved that it is not necessarily true that there is a correspondence between knowledge quality and construction of the education system, i.e. that the former quality is not an inevitable condition of the latter. In the first part of the paper, we distinguish the concept of quality from non-quality knowledge. Out of 19 indicators, five knowledge qualities are normative (exceptional sense, and the others descriptive (specific sense characteristics. In the second part, the conceptual approach to education system focuses on its (dysfunctional and non-functional connections. The tradition of national knowledge, the character of social relations established between the actors within the system and the influence of implicit knowledge on teacher and student actions in education system are discussed. All these factors can influence positively and negatively the direction and content of knowledge quality in education system. Knowledge quality in school curricula and textbooks may be ensured and then (not realized due to the influence of traditional, social and implicit factors on educational interaction. The concept of constellation is used to explain the favorable and unfavorable relation between knowledge quality and education system. In the concluding part, the author argues that education system cannot ensure complete realization of knowledge quality since it is, to a considerable extent, conditioned by school and non-school factors.

  9. Birds of Pernambuco: Current state of ornithological knowledge

    Directory of Open Access Journals (Sweden)

    Gilmar Beserra de Farias

    2009-09-01

    Full Text Available An analysis of the present state of ornithological knowledge is required for the guidance of researchers in their future investigations. This work provides a survey of literature describing the development of ornithological research in the state. Between 1880 and 2008, many lists were organized, which contributed towards the systematization of the knowledge about Pernambuco’s birds. Out if the 535 species recorded, 49 are found in marine environments or wetlands, 450 occur in the Atlantic Rainforest, and 270 reside in the semi-arid Caatinga. We suggest that studies on the birds of the Caatinga are most important and should be prioritized at present, in addition to effective actions for the conservation of endemic species and of species under risk of extinction.

  10. Current and future trends in metagenomics : Development of knowledge bases

    Science.gov (United States)

    Mori, Hiroshi; Yamada, Takuji; Kurokawa, Ken

    Microbes are essential for every part of life on Earth. Numerous microbes inhabit the biosphere, many of which are uncharacterized or uncultivable. They form a complex microbial community that deeply affects against surrounding environments. Metagenome analysis provides a radically new way of examining such complex microbial community without isolation or cultivation of individual bacterial community members. In this article, we present a brief discussion about a metagenomics and the development of knowledge bases, and also discuss about the future trends in metagenomics.

  11. THE KNOWLEDGE SOCIETY AND THE INFORMATION SOCIETY. THE CURRENT SITUATION IN ROMANIA

    OpenAIRE

    STELIAC Nela; POP Ciprian-Viorel; Diana-Aderina MOISUC

    2012-01-01

    Currently, human societies are experiencing a new type of economy: the knowledge economy which is founded on a knowledge society. The main driver of social and economic growth is knowledge itself. The new economy requires a rethinking of the production theory in that traditional factors change into secondary factors, while knowledge becomes the main, essential, production factor. An information society is a prerequisite stage towards a knowledge society; hence it needs to be implemented first...

  12. A Systematic Review of Athletes’ and Coaches’ Nutrition Knowledge and Reflections on the Quality of Current Nutrition Knowledge Measures

    Science.gov (United States)

    Trakman, Gina L.; Forsyth, Adrienne; Devlin, Brooke L.; Belski, Regina

    2016-01-01

    Context: Nutrition knowledge can influence dietary choices and impact on athletic performance. Valid and reliable measures are needed to assess the nutrition knowledge of athletes and coaches. Objectives: (1) To systematically review the published literature on nutrition knowledge of adult athletes and coaches and (2) to assess the quality of measures used to assess nutrition knowledge. Data Sources: MEDLINE, CINAHL, SPORTDiscuss, Web of Science, and SCOPUS. Study Selection: 36 studies that provided a quantitative measure of nutrition knowledge and described the measurement tool that was used were included. Data extraction: Participant description, questionnaire description, results (mean correct and responses to individual items), study quality, and questionnaire quality. Data synthesis: All studies were of neutral quality. Tools used to measure knowledge did not consider health literacy, were outdated with regards to consensus recommendations, and lacked appropriate and adequate validation. The current status of nutrition knowledge in athletes and coaches is difficult to ascertain. Gaps in knowledge also remain unclear, but it is likely that energy density, the need for supplementation, and the role of protein are frequently misunderstood. Conclusions: Previous reports of nutrition knowledge need to be interpreted with caution. A new, universal, up-to-date, validated measure of general and sports nutrition knowledge is required to allow for assessment of nutrition knowledge. PMID:27649242

  13. A Systematic Review of Athletes’ and Coaches’ Nutrition Knowledge and Reflections on the Quality of Current Nutrition Knowledge Measures

    Directory of Open Access Journals (Sweden)

    Gina L. Trakman

    2016-09-01

    Full Text Available Context: Nutrition knowledge can influence dietary choices and impact on athletic performance. Valid and reliable measures are needed to assess the nutrition knowledge of athletes and coaches. Objectives: (1 To systematically review the published literature on nutrition knowledge of adult athletes and coaches and (2 to assess the quality of measures used to assess nutrition knowledge. Data Sources: MEDLINE, CINAHL, SPORTDiscuss, Web of Science, and SCOPUS. Study Selection: 36 studies that provided a quantitative measure of nutrition knowledge and described the measurement tool that was used were included. Data extraction: Participant description, questionnaire description, results (mean correct and responses to individual items, study quality, and questionnaire quality. Data synthesis: All studies were of neutral quality. Tools used to measure knowledge did not consider health literacy, were outdated with regards to consensus recommendations, and lacked appropriate and adequate validation. The current status of nutrition knowledge in athletes and coaches is difficult to ascertain. Gaps in knowledge also remain unclear, but it is likely that energy density, the need for supplementation, and the role of protein are frequently misunderstood. Conclusions: Previous reports of nutrition knowledge need to be interpreted with caution. A new, universal, up-to-date, validated measure of general and sports nutrition knowledge is required to allow for assessment of nutrition knowledge.

  14. Diagnosis and management of chronic pancreatitis: current knowledge.

    Science.gov (United States)

    Ammann, Rudolf W

    2006-03-18

    This paper reviews the current literature on chronic pancreatitis (CP). Despite marked progress in diagnostic tools, predominately imaging methods, no consensus has been reached on the nomenclature of CP, ie diagnosis, classification, staging, pathomechanisms of pain and its optimal treatment. A major problem is that no single reliable diagnostic test exists for early-stage CP except histopathology (rarely available). This stage is characterised typically by recurrent acute pancreatitis +/- necrosis (eg pseudocysts). Acute pancreatitis is a well-defined condition caused in 80% of cases by gallstones or alcohol abuse. Alcoholic pancreatitis, in contrast to biliary pancreatitis, progresses to CP in the majority of patients. However, a definite CP-diagnosis is often delayed because progressive dysfunction and/or calcification, the clinical markers of CP, develop on average 5 years from disease onset. The progression rate is variable and depends on several factors eg aetiology, smoking, continued alcohol abuse. Repeated function testing eg by the faecal elastase test, is the best alternative for histology to monitor progression (or non-progression) of suspected (probable) to definite CP. The pathomechanism of pain in CP is multifactorial and data from different series are hardly comparable mainly because insufficient data of the various variables ie diagnosis, classification, staging of CP, pain pattern and presumptive pain cause, are provided. Pain in CP is rarely intractable except in the presence of cancer, opiate addiction or extra-pancreatic pain causes. Local complications like pseudocysts or obstructive cholestasis are the most common causes of severe persistent pain which can be relieved promptly by an appropriate drainage procedure. Notably, partial to complete pain relief is a common feature in 50-80% of patients with late-stage CP irrespective of surgery and about 50% of CP-patients never need surgery (or endoscopic intervention). The spontaneous "burn

  15. Assessment of knowledge and awareness among radiology personnel regarding current computed tomography technology and radiation dose

    Science.gov (United States)

    Karim, M. K. A.; Hashim, S.; Bradley, D. A.; Bahruddin, N. A.; Ang, W. C.; Salehhon, N.

    2016-03-01

    In this paper, we evaluate the level of knowledge and awareness among 120 radiology personnel working in 7 public hospitals in Johor, Malaysia, concerning Computed Tomography (CT) technology and radiation doses based on a set of questionnaires. Subjects were divided into two groups (Medical profession (Med, n=32) and Allied health profession (AH, n=88). The questionnaires are addressed: (1) demographic data (2) relative radiation dose and (3) knowledge of current CT technology. One-third of respondents from both groups were able to estimate relative radiation dose for routine CT examinations. 68% of the allied health profession personnel knew of the Malaysia regulations entitled ‘Basic Safety Standard (BSS) 2010’, although notably 80% of them had previously attended a radiation protection course. No significant difference (p < 0.05) in mean scores of CT technology knowledge detected between the two groups, with the medical professions producing a mean score of (26.7 ± 2.7) and the allied health professions a mean score of (25.2 ± 4.3). This study points to considerable variation among the respondents concerning their understanding of knowledge and awareness of risks of radiation and CT optimization techniques.

  16. Immunotherapies Targeting Fish Mucosal Immunity - Current Knowledge and Future Perspectives.

    Science.gov (United States)

    Koshio, Shunsuke

    2015-01-01

    In recent years, studies on the mucosal immunity in fish species have shown much progress. Although there are some organs such as skin, gills, and gut are directly associated with the mucosal immunity of fish species, this mini review emphasizes the general knowledge on the role and production figures of skin mucus and factors affecting the secretion of skin mucus of fish species. As the skin mucus of fish species is the first defense line for protection against invading microorganisms such as pathogens (bacteria, virus), parasites, etc., the information for understanding the roles of the skin mucus is very important. Furthermore, the information in the review will shed light on the development of high quality aquafeeds for the sustainable aquaculture field as well.

  17. CURRENT SCENARIO: KNOWLEDGE OF BASIC LIFE SUPPORT IN MEDICAL COLLEGE

    Directory of Open Access Journals (Sweden)

    Asmita Chaudhary

    2011-04-01

    Full Text Available A workshop has been conducted on basic skill of Cardio-Pulmonary Resuscitation (CPR among doctors and nursing staff in medical college. Theoretical aspect was explained through power point presentation whereas practical aspect was demonstrated through skill station. The results were analyzed by using an answer key prepared from BLS manual of American Heart Association (AHA. Out of 117 participants only three participants secured 80-90% marks in pretest whereas rest of secured less than 50% marks .Post workshop assessment was done with same question papers showed 70% candidates securing more than 80%. Hence BLS workshop is essential to improve knowledge and skill of CPR. [National J of Med Res 2011; 1(2.000: 80-82

  18. oral health related behaviour, knowledge, attitudes and beliefs ...

    African Journals Online (AJOL)

    OBJECTIVES. To determine oral health related behavior, knowledge, attitudes and beliefs among secondary school ... necessary interventions that can be undertaken .... (t = -2.244, p value =0.025) .... Oral Hygiene Practices, Smoking Habits,.

  19. Sport-related concussions: knowledge translation among minor hockey coaches.

    Science.gov (United States)

    Mrazik, Martin; Bawani, Farzad; Krol, Andrea L

    2011-07-01

    The objective of this study was to investigate minor hockey coaches' knowledge base of sport-related concussions. Cross-sectional survey. Subjects independently completed the written survey at preseason organizational meetings. One hundred seventy-eight active coaches spanning 5 age levels (ages 5-15 years). Coaches reported 2.62 ± 3.73 years of coaching experience. Resources where coaches obtained information about concussions, perceptions of variables associated with concussions, knowledge level of issues associated with concussions, and decision-making practices. Newspapers and magazines were the most frequent source of information regarding concussions, yet were rated as not very helpful. Family physicians were less frequently sought but were rated as most helpful. A majority of coaches reported limited knowledge about concussions but rated this knowledge as being important. There was a significant relationship between head coaching experience and concussion knowledge [R = 0.09, F3,156 = 4.41, P = 0.005]. Most coaches demonstrated a good knowledge base of common issues associated with concussions, and a majority of individuals correctly identified return-to-play practices. A majority of minor hockey coaches correctly recognized and understood issues related to sport-related concussions. Results suggested that knowledge translation through various formal and informal sources has had a positive effect. However, a majority of coaches reported having limited knowledge about concussions yet consider it an important topic.

  20. Arrhythmogenic KCNE gene variants: current knowledge and future challenges

    Directory of Open Access Journals (Sweden)

    Shawn M Crump

    2014-01-01

    Full Text Available There are twenty-five known inherited cardiac arrhythmia susceptibility genes, all of which encode either ion channel pore-forming subunits or proteins that regulate aspects of ion channel biology such as function, trafficking and localization. The human KCNE gene family comprises five potassium channel regulatory subunits, sequence variants in each of which are associated with cardiac arrhythmias. KCNE gene products exhibit promiscuous partnering and in some cases ubiquitous expression, hampering efforts to unequivocally correlate each gene to specific native potassium currents. Likewise, deducing the molecular etiology of cardiac arrhythmias in individuals harboring rare KCNE gene variants, or more common KCNE polymorphisms, can be challenging. In this review we provide an update on putative arrhythmia-causing KCNE gene variants, and discuss current thinking and future challenges in the study of molecular mechanisms of KCNE-associated cardiac rhythm disturbances.

  1. Current knowledge on diabetic retinopathy from humandonor tissues

    Institute of Scientific and Technical Information of China (English)

    Jessica H Eisma; Jennifer E Dulle; Patrice E Fort

    2015-01-01

    According to the American Diabetes Association, diabetes was the seventh leading cause of death, and diabetic retinopathy the leading cause of blindness in working age adults in the United States in 2010. Diabetes is characterized by hyperglycemia associated with either hypoinsulinemia or insulin resistance, and over time, this chronic metabolic condition may lead to various complications including kidney failure, heart attacks,and retinal degeneration. In order to better understandthe molecular basis of this disease and its complications,animal models have been the primary approach usedto investigate the effects of diabetes on various tissuesor cell types of the body, including the retina. However,inherent to these animal models are critical limitationsthat make the insight gained from these modelschallenging to apply to the human pathology. Thesedifficulties in translating the knowledge obtained fromanimal studies have led a growing number of researchgroups to explore the diabetes complications, especiallydiabetic retinopathy, on tissues from human donors.This review summarizes the data collected from diabeticpatients at various stages of diabetic retinopathy andclassifies the data based upon their relevance to themain aspects of diabetic retinopathy: retinal vasculaturedysfunction, inflammation, and neurodegeneration. Thisreview discusses the importance of those studies todiscriminate and establish the relevance of the findingsobtained from animal models but also the limitations ofsuch approaches.

  2. Vitamin K metabolism: current knowledge and future research.

    Science.gov (United States)

    Card, David J; Gorska, Renata; Cutler, Jacky; Harrington, Dominic J

    2014-08-01

    Vitamin K is an essential fat-soluble micronutrient that is required for the post-translational γ-carboxylation of specific glutamic acid residues in hepatic and extra-hepatic proteins involved in blood coagulation and preventing cartilage and vasculature calcification. In humans, sources of vitamin K are derived from plants as phylloquinone and bacteria as the menaquinones. Menadione is a synthetic product used as a pharmaceutical but also represents an intermediate in the tissue-specific conversion of vitamin K to menaquinone-4, which preferentially resides in tissues such as brain. Research into vitamin K metabolism is essential for the understanding of vitamin K biology in health and disease. Progress in this area, driven by knowledge of vitamin K and the availability of markers of vitamin K status, has already proved beneficial in many areas of medicine and further opportunities present themselves. Areas of interest discussed in this review include prophylactic administration of vitamin K1 in term and preterm neonates, interactions between vitamins K and E, the industrial conversion of vitamin K to dihydro-vitamin K in foods, tissue-specific conversion of vitamin K to menaquinone-4, the biological activity of the five and seven carbon metabolites of vitamin K and circadian variations.

  3. The Effect of the "Weekly Reader" on Children's Knowledge of Current Events.

    Science.gov (United States)

    Hofstetter, Carolyn Huie; Hofstetter, C. Richard; Lapp, Diane; Flood, James

    2000-01-01

    Studied the effects of reading the "Weekly Reader" on children's knowledge of current events. Results from 2,331 urban and suburban elementary school students, aged 8 to 12, show increased knowledge of current events among younger children who used the "Weekly Reader," but the effect was less in grades 4 through 6. (SLD)

  4. Prediction of severe acute pancreatitis: Current knowledge and novel insights

    Institute of Scientific and Technical Information of China (English)

    Georgios I Papachristou

    2008-01-01

    Acute pancreatitis (AP) is a common and potentially lethal acute inflammatory process with a highly variable clinical course. It is still unclear why some patients progress to organ failure and others do not. Physicians, ability to predict which patients will develop severe disease is limited. Routine clinical and laboratory data and multi-factorial clinical scores measured on admission and during the first 48 h of hospitalization are currently the standards of care used to estimate the magnitude of the inflammatory response to injury. Current literature highlights several common environmental, metabolic and genetic factors that increase the risk of AP development and subsequent adverse sequelae. Several cytokines have been found to play a critical role in the pathogenesis of AP by driving the subsequent inflammatory response, to include tumor necrosis factor-α (TNF-α), Interleukin-1 (IL-1), IL-6 and monocyte chemotactic protein-1 (HCP-1). Large, prospective studies are still needed to address these questions by identifying AP risk factors and serum biomarkers of severe disease.

  5. Current knowledge of the aetiology of human tubal ectopic pregnancy

    Science.gov (United States)

    Shaw, J.L.V.; Dey, S.K.; Critchley, H.O.D.; Horne, A.W.

    2010-01-01

    BACKGROUND An ectopic pregnancy is a pregnancy which occurs outside of the uterine cavity, and over 98% implant in the Fallopian tube. Tubal ectopic pregnancy remains the most common cause of maternal mortality in the first trimester of pregnancy. The epidemiological risk factors for tubal ectopic pregnancy are well established and include: tubal damage as a result of surgery or infection (particularly Chlamydia trachomatis), smoking and in vitro fertilization. This review appraises the data to date researching the aetiology of tubal ectopic pregnancy. METHODS Scientific literature was searched for studies investigating the underlying aetiology of tubal ectopic pregnancy. RESULTS Existing data addressing the underlying cause of tubal ectopic pregnancy are mostly descriptive. There are currently few good animal models of tubal ectopic pregnancy. There are limited data explaining the link between risk factors and tubal implantation. CONCLUSIONS Current evidence supports the hypothesis that tubal ectopic pregnancy is caused by a combination of retention of the embryo within the Fallopian tube due to impaired embryo-tubal transport and alterations in the tubal environment allowing early implantation to occur. Future studies are needed that address the functional consequences of infection and smoking on Fallopian tube physiology. A greater understanding of the aetiology of tubal ectopic pregnancy is critical for the development of improved preventative measures, the advancement of diagnostic screening methods and the development of novel treatments. PMID:20071358

  6. How does relativity affect magnetically induced currents?

    Science.gov (United States)

    Berger, R J F; Repisky, M; Komorovsky, S

    2015-09-21

    Magnetically induced probability currents in molecules are studied in relativistic theory. Spin-orbit coupling (SOC) enhances the curvature and gives rise to a previously unobserved current cusp in AuH or small bulge-like distortions in HgH2 at the proton positions. The origin of this curvature is magnetically induced spin-density arising from SOC in the relativistic description.

  7. Anterior point of reference: Current knowledge and perspectives in prosthodontics

    Directory of Open Access Journals (Sweden)

    Prince Kumar

    2012-01-01

    Full Text Available The opening and closing mandibular axis is not a purely theoretical postulation, but an absolutely demonstrable biomechanical entity. It is very crucial to accurately record and transfer to articulators for the purpose of maxillofacial rehabilitation. Following the Face bow record and transfer of the mandibular axis to an anatomic articulator, we can then mount the casts so that they open and close on the articulator in the same fashion as the patient′s jaws. For this reason one of the fixed factors presented by the patient is taken into the consideration, which if properly considered, can be of inestimable value in all phases of dental treatment. This paper has sought to review the current concepts and practical implications regarding anterior point of reference in prosthodontics.

  8. Police peer support programs: current knowledge and practice.

    Science.gov (United States)

    Grauwiler, Peggy; Barocas, Briana; Mills, Linda G

    2008-01-01

    This review examines the current empirical research and literature on peer assistance programs, peer support, and peer-facilitated interventions for police officers. A literature search was conducted to identify studies on police, peer support, and peer assistance programs. Studies were examined in terms of the following criteria: description of data collection methods, findings, study limitations, implications for police, workplace assistance, and peer support. Articles on peer support in the aftermath of the September 11, 2001, World Trade Center rescue and recovery efforts were also reviewed. The research studies reviewed in this article do not evaluate peer program effectiveness from the perspective of those officers receiving peer services. To better serve this invaluable population, efforts must be made to incorporate their views. Information is also needed on the effectiveness of peer assistance programs and peer-driven crisis intervention models. Finally, research is needed that specifically examines the effectiveness of programs that utilize trained peers in partnership with professional mental health practitioners.

  9. Cyberbullying Prevention and Intervention Efforts: Current Knowledge and Future Directions.

    Science.gov (United States)

    Espelage, Dorothy L; Hong, Jun Sung

    2017-06-01

    Bullying is a serious public health concern that is associated with significant negative mental, social, and physical outcomes. Technological advances have increased adolescents' use of social media, and online communication platforms have exposed adolescents to another mode of bullying- cyberbullying. Prevention and intervention materials, from websites and tip sheets to classroom curriculum, have been developed to help youth, parents, and teachers address cyberbullying. While youth and parents are willing to disclose their experiences with bullying to their health care providers, these disclosures need to be taken seriously and handled in a caring manner. Health care providers need to include questions about bullying on intake forms to encourage these disclosures. The aim of this article is to examine the current status of cyberbullying prevention and intervention. Research support for several school-based intervention programs is summarised. Recommendations for future research are provided.

  10. Patient Participation: Current Knowledge and Applicability to Patient Safety

    OpenAIRE

    Longtin, Yves; Sax, Hugo; Leape, Lucian L; Sheridan, Susan E.; Donaldson, Liam; Pittet, Didier

    2010-01-01

    Patient participation is increasingly recognized as a key component in the redesign of health care processes and is advocated as a means to improve patient safety. The concept has been successfully applied to various areas of patient care, such as decision making and the management of chronic diseases. We review the origins of patient participation, discuss the published evidence on its efficacy, and summarize the factors influencing its implementation. Patient-related factors, such as accept...

  11. Power relations and reciprocity: dialectics of knowledge construction.

    Science.gov (United States)

    Ben-Ari, Adital; Enosh, Guy

    2013-03-01

    In this article we suggest a theoretical framework of knowledge construction by employing the concept of dialectics to power relationships between researcher and participants. Power distribution in research is perceived as dichotomous and asymmetrical in favor of the researcher, creating unequal power relations that make exploitation possible. Acknowledging such exploitation has led to a critical stance and attempts to bridge gaps through egalitarianism and empowerment of participants. Some scholars have focused on shifting expert knowledge differentials between researcher and participants throughout the research project. Others have evaluated such gaps as a source of knowledge construction. In the present work we applied a dialectical approach to understanding research relationships, suggesting reciprocity as their defining attribute, regardless of symmetry or asymmetry and as a source of knowledge construction. In this article we recommend avoiding a taken-for-granted attitude, because we see it as a direct obstacle to the construction of knowledge.

  12. Are iron oxide nanoparticles safe? Current knowledge and future perspectives.

    Science.gov (United States)

    Valdiglesias, Vanessa; Fernández-Bertólez, Natalia; Kiliç, Gözde; Costa, Carla; Costa, Solange; Fraga, Sonia; Bessa, Maria Joao; Pásaro, Eduardo; Teixeira, João Paulo; Laffon, Blanca

    2016-12-01

    Due to their unique physicochemical properties, including superparamagnetism, iron oxide nanoparticles (ION) have a number of interesting applications, especially in the biomedical field, that make them one of the most fascinating nanomaterials. They are used as contrast agents for magnetic resonance imaging, in targeted drug delivery, and for induced hyperthermia cancer treatments. Together with these valuable uses, concerns regarding the onset of unexpected adverse health effects following exposure have been also raised. Nevertheless, despite the numerous ION purposes being explored, currently available information on their potential toxicity is still scarce and controversial data have been reported. Although ION have traditionally been considered as biocompatible - mainly on the basis of viability tests results - influence of nanoparticle surface coating, size, or dose, and of other experimental factors such as treatment time or cell type, has been demonstrated to be important for ION in vitro toxicity manifestation. In vivo studies have shown distribution of ION to different tissues and organs, including brain after passing the blood-brain barrier; nevertheless results from acute toxicity, genotoxicity, immunotoxicity, neurotoxicity and reproductive toxicity investigations in different animal models do not provide a clear overview on ION safety yet, and epidemiological studies are almost inexistent. Much work has still to be done to fully understand how these nanomaterials interact with cellular systems and what, if any, potential adverse health consequences can derive from ION exposure.

  13. Exercise proteinuria and hematuria: current knowledge and future directions.

    Science.gov (United States)

    Shephard, Roy J

    2016-09-01

    Transient proteinuria and hematuria are apparently benign sequelae of intensive physical activity. However, there is a need to establish underlying causes and reasons for progression to chronic renal damage, as well as effects of training in healthy individuals and in those with microalbuminuria. The Ovid/Health Star database was searched from 1994 to November 2014. Terms for the kidneys (adverse effects, blood supply, epidemiology, injuries, pathology, physiology and secretion) and proteinuria (classification, complications, epidemiology, etiology, mortality, physiopathology, prevention and control) with terms related to physical activity (physical activity/motor activity, exercise/exercise therapy, fitness/physical fitness, physical education/physical education and training, and rehabilitation). Review of 519 abstracts yielded 194 relevant hits, supplemented by 70 items from other sources. This material related to both healthy adults (125 items) and renal disease (139 items). The prevalence (18-100%) and duration (1-6 days) of exercise proteinuria varied widely, with risks affected by exercise intensity, posture, age, heat load, altitude and disease. Moderate training reduced exercise proteinuria in healthy individuals and in chronic renal disease. Factors contributing to exercise proteinuria may include vascular changes, hypoxia, lactate accumulation, oxidant stress, hormonal changes and sepsis. Exercise hematuria is frequent; some potential causes are similar to those for proteinuria, but foot-strike and bladder trauma are probably more important. Progression to permanent renal damage is rare. Exercise proteinuria and hematuria are generally transient. However, there remains a need to clarify causation and factors leading to permanent renal damage.

  14. Awareness, Knowledge, and Concern about Age-Related Macular Degeneration

    Science.gov (United States)

    Cimarolli, Verena R.; Laban-Baker, Allie; Hamilton, Wanda S.; Stuen, Cynthia

    2012-01-01

    Age-related macular degeneration (AMD)--a common eye disease causing vision loss--can be detected early through regular eye-health examinations, and measures can be taken to prevent visual decline. Getting eye examinations requires certain levels of awareness, knowledge, and concern related to AMD. However, little is known about AMD-related…

  15. Subglacial Lake Whillans microbial biogeochemistry: a synthesis of current knowledge.

    Science.gov (United States)

    Mikucki, J A; Lee, P A; Ghosh, D; Purcell, A M; Mitchell, A C; Mankoff, K D; Fisher, A T; Tulaczyk, S; Carter, S; Siegfried, M R; Fricker, H A; Hodson, T; Coenen, J; Powell, R; Scherer, R; Vick-Majors, T; Achberger, A A; Christner, B C; Tranter, M

    2016-01-28

    Liquid water occurs below glaciers and ice sheets globally, enabling the existence of an array of aquatic microbial ecosystems. In Antarctica, large subglacial lakes are present beneath hundreds to thousands of metres of ice, and scientific interest in exploring these environments has escalated over the past decade. After years of planning, the first team of scientists and engineers cleanly accessed and retrieved pristine samples from a West Antarctic subglacial lake ecosystem in January 2013. This paper reviews the findings to date on Subglacial Lake Whillans and presents new supporting data on the carbon and energy metabolism of resident microbes. The analysis of water and sediments from the lake revealed a diverse microbial community composed of bacteria and archaea that are close relatives of species known to use reduced N, S or Fe and CH4 as energy sources. The water chemistry of Subglacial Lake Whillans was dominated by weathering products from silicate minerals with a minor influence from seawater. Contributions to water chemistry from microbial sulfide oxidation and carbonation reactions were supported by genomic data. Collectively, these results provide unequivocal evidence that subglacial environments in this region of West Antarctica host active microbial ecosystems that participate in subglacial biogeochemical cycling.

  16. Impact of nanoparticles on DNA repair processes: current knowledge and working hypotheses.

    Science.gov (United States)

    Carriere, Marie; Sauvaigo, Sylvie; Douki, Thierry; Ravanat, Jean-Luc

    2017-01-01

    The potential health effects of exposure to nanomaterials (NMs) is currently heavily studied. Among the most often reported impact is DNA damage, also termed genotoxicity. While several reviews relate the DNA damage induced by NMs and the techniques that can be used to prove such effects, the question of impact of NMs on DNA repair processes has never been specifically reviewed. The present review article proposes to fill this gap of knowledge by critically describing the DNA repair processes that could be affected by nanoparticle (NP) exposure, then by reporting the current state of the art on effects of NPs on DNA repair, at the level of protein function, gene induction and post-transcriptional modifications, and taking into account the advantages and limitations of the different experimental approaches. Since little is known about this impact, working hypothesis for the future are then proposed.

  17. CURRENT KNOWLEDGE ON HIV-ASSOCIATED PLASMABLASTIC LYMPHOMA

    Directory of Open Access Journals (Sweden)

    Michele Bibas

    2014-10-01

    Full Text Available HIV-associated PBL is an AIDS-defining cancer, classified by WHO as distinct entity of aggressive DLBCL. To date less than 250 cases have been published, of them17 are pediatric. The pathogenesis of this rare disease is related to immunodefiency, chronic immune stimulation and EBV. Clinically is a rapid growing destructive disease mainly of oral cavity, but frequently involves extraoral and extranodal sites. The diagnosis requires tissue mass or lymph node biopsy, but  core needle or fine needle biopsy is acceptable for difficult access sites. Immunophenotype is CD45, CD20, CD79a negative and CD38, CD138, MUM1 positive, EBER and KI67 is >80%. Frequently is diagnosed in patients with low CD4+ and high viral load, however is reported also in patients on effective cART and high CD4. Treatment administered is usually CHOP or CHOP-like regimens, more intensive regimens as CODOX-M/IVAC or DA-EPOCH are possible options. Intensification with ABMT in CR1 may be  considered for fit patients. Rituximab is not useful for this CD20- disease. Bortezomib and new drugs were used at case report level, with transient response. CNS prophylaxis is mandatory. Use of cART is recommended during chemotherapy, keeping in mind the possible overlapping toxicities. For refractory/relapsed patients, therapy is usually considered  palliative, however in chemosensitive disease intensification + ABMT or new drugs may be considered. Factors affecting outcome are achieving complete remission, PS, clinical stage, MYC , IPI. Reported median PFS ranges between  6-7 months and median OS ranges between 11-13 months. Long term survivor are reported but mostly in pediatric patients.  Due to the scarcity of data on this subtype of NHL we suggest that the diagnosis and the management of HIV-positive PBL patients should be performed in specialized centers.

  18. [Global spread of Zika virus epidemic: current knowledges and uncertainties].

    Science.gov (United States)

    Şahiner, Fatih

    2016-04-01

    Zika virus (ZIKV) is an enveloped RNA virus that belongs to the Flaviviridae family. Although more than 60 years have passed since the discovery and first reported human cases of the virus, only a small number (Zika virus was known as a virus which caused sporadic infections and was confined to Africa and Asia along a narrow equatorial line. In 2007, however, the first major outbreak of ZIKV occurred in Yap Island (Micronesia), and so it was reported for the first time outside of Africa and Asia. Between the years of 2007 and 2014, ZIKV spreaded to island groups located in Southeast Asia and the Pacific Ocean, and in 2015-2016, it has spread to South and Central America and the Caribbean. Today, travel-related imported cases is still been reported in Europe, North America, and other countries in the Far East. According to the data from the World Health Organization and the Centers for Disease Control and Prevention, as of March 2016, ZIKV infections have already spread locally in more than 30 countries, and travel alerts have been issued for the countries where the virus is present. Zika virus infections are generally asymptomatic or may present with a moderate clinical picture (e.g. acute onset of fever, maculopapular rash, arthralgia, and nonpurulent conjunctivitis). Although no deaths were attributed to ZIKV infection over the past 60 years, as of November 2015, it has been suggested that three deaths in Brazil, including the death of a newborn with microcephaly, may be attributed to ZIKV infection. In addition, concurrent with outbreaks in 2013 in French Polynesia and in 2015 in Brazil, there have been significant rises reported in the incidence of some autoimmune and neurodevelopmental disorders, including Guillain-Barre syndrome and microcephaly; these reports have caused considerable international concern. There are many points that are still unclear about ZIKV, including: (1) intrauterine transmission risk, frequency, and effects of the infection on fetal

  19. Science and cycling: current knowledge and future directions for research.

    Science.gov (United States)

    Atkinson, Greg; Davison, Richard; Jeukendrup, Asker; Passfield, Louis

    2003-09-01

    In this holistic review of cycling science, the objectives are: (1) to identify the various human and environmental factors that influence cycling power output and velocity; (2) to discuss, with the aid of a schematic model, the often complex interrelationships between these factors; and (3) to suggest future directions for research to help clarify how cycling performance can be optimized, given different race disciplines, environments and riders. Most successful cyclists, irrespective of the race discipline, have a high maximal aerobic power output measured from an incremental test, and an ability to work at relatively high power outputs for long periods. The relationship between these characteristics and inherent physiological factors such as muscle capilliarization and muscle fibre type is complicated by inter-individual differences in selecting cadence for different race conditions. More research is needed on high-class professional riders, since they probably represent the pinnacle of natural selection for, and physiological adaptation to, endurance exercise. Recent advances in mathematical modelling and bicycle-mounted strain gauges, which can measure power directly in races, are starting to help unravel the interrelationships between the various resistive forces on the bicycle (e.g. air and rolling resistance, gravity). Interventions on rider position to optimize aerodynamics should also consider the impact on power output of the rider. All-terrain bicycle (ATB) racing is a neglected discipline in terms of the characterization of power outputs in race conditions and the modelling of the effects of the different design of bicycle frame and components on the magnitude of resistive forces. A direct application of mathematical models of cycling velocity has been in identifying optimal pacing strategies for different race conditions. Such data should, nevertheless, be considered alongside physiological optimization of power output in a race. An even distribution

  20. Nonadherence is Associated with Lack of HIV-Related Knowledge

    DEFF Research Database (Denmark)

    Dyrehave, Charlotte; Rasmussen, Dlama Nggida; Hønge, Bo Langhoff

    2016-01-01

    -sectional study included 494 HIV-infected individuals from the Bissau HIV Cohort in Guinea-Bissau. They completed a questionnaire designed for assessment of adherence and HIV-related knowledge. RESULTS: A majority were female, 41% were illiterate, 25% did not take the medicine during the last 4 days, and 23......BACKGROUND: Poor treatment adherence is a main barrier for effective antiretroviral therapy (ART) globally. HIV-related knowledge may affect understanding and utilization of HIV medical information, hence limited health literacy is a known barrier to treatment adherence. DESIGN AND METHODS: A cross......% skipped their medicine during weekends. The most frequent reasons for not taking medicine were simply forgetting, side effects, lack of food, and being too ill to attend the clinic. Nonadherent patients had a lower level of HIV-related knowledge. CONCLUSION: Main barriers for nonadherence were side...

  1. Hepatitis B Virus Infection in Iran: Current Knowledge, Future Plans

    Directory of Open Access Journals (Sweden)

    Hossein Khedmat

    2009-09-01

    Full Text Available Dear Editor,.We greatly enjoyed reading the excellent review article by Alavian, et al., (1 on the epidemiology of hepatitis B virus (HBV infection in Iranian general population. Reviewing over 250 related articles in this paper as well as inclusion of non-published reports from libraries of different universities of all parts of the country, has made the paper so perfect that one may find any data derived from different studies on the epidemiology of HBV infection in Iran within this article. Iran is located in a region with intermediate endemicity for HBV infection (2. Although, considering the findings presented in this article, it becomes clear that there is no homogeneity in the epidemiology of HBV infection in different parts of our country, no explanation why such disparities exist were presented. According to the article, Golestan province is one of the most infected provinces. This province is near Central Asia which is a known area for high HBV infection rates (2; on the other hand, we have no data on the three Khorasan provinces where are also in the neighborhood of the Central Asia and host many tourists annually. If this is the major cause, one may presume that the prevalence of HBV infection in the Khorasan should also be high. So, as it was also recommended in the article, one of the most urgent things we must do is to understand the risk factors for transmission of the virus in different parts of the country. .In that article, it was also mentioned that although more than 100 articles overlapping the same issue are available for some provinces, we had no data on the issue for 23 (77% of the provinces of our country. This fact emphasizes on considering new studies to be conducted to evaluate the issue in all parts of our country whose data is of utmost importance for future health planning. On the other hand, several studies were also excluded from the analysis because of their flawed methodology. This issue is also one of the

  2. Error-Related Negativities During Spelling Judgments Expose Orthographic Knowledge

    Science.gov (United States)

    Harris, Lindsay N.; Perfetti, Charles A.; Rickles, Benjamin

    2014-01-01

    In two experiments, we demonstrate that error-related negativities (ERNs) recorded during spelling decisions can expose individual differences in lexical knowledge. The first experiment found that the ERN was elicited during spelling decisions and that its magnitude was correlated with independent measures of subjects’ spelling knowledge. In the second experiment, we manipulated the phonology of misspelled stimuli and observed that ERN magnitudes were larger when misspelled words altered the phonology of their correctly spelled counterparts than when they preserved it. Thus, when an error is made in a decision about spelling, the brain processes indexed by the ERN reflect both phonological and orthographic input to the decision process. In both experiments, ERN effect sizes were correlated with assessments of lexical knowledge and reading, including offline spelling ability and spelling-mediated vocabulary knowledge. These results affirm the interdependent nature of orthographic, semantic, and phonological knowledge components while showing that spelling knowledge uniquely influences the ERN during spelling decisions. Finally, the study demonstrates the value of ERNs in exposing individual differences in lexical knowledge. PMID:24389506

  3. Error-related negativities during spelling judgments expose orthographic knowledge.

    Science.gov (United States)

    Harris, Lindsay N; Perfetti, Charles A; Rickles, Benjamin

    2014-02-01

    In two experiments, we demonstrate that error-related negativities (ERNs) recorded during spelling decisions can expose individual differences in lexical knowledge. The first experiment found that the ERN was elicited during spelling decisions and that its magnitude was correlated with independent measures of subjects' spelling knowledge. In the second experiment, we manipulated the phonology of misspelled stimuli and observed that ERN magnitudes were larger when misspelled words altered the phonology of their correctly spelled counterparts than when they preserved it. Thus, when an error is made in a decision about spelling, the brain processes indexed by the ERN reflect both phonological and orthographic input to the decision process. In both experiments, ERN effect sizes were correlated with assessments of lexical knowledge and reading, including offline spelling ability and spelling-mediated vocabulary knowledge. These results affirm the interdependent nature of orthographic, semantic, and phonological knowledge components while showing that spelling knowledge uniquely influences the ERN during spelling decisions. Finally, the study demonstrates the value of ERNs in exposing individual differences in lexical knowledge. Copyright © 2013 Elsevier Ltd. All rights reserved.

  4. Teachers' Literacy-Related Knowledge and Self-Perceptions in Relation to Preparation and Experience

    Science.gov (United States)

    Spear-Swerling, Louise; Brucker, Pamela Owen; Alfano, Michael P.

    2005-01-01

    After rating their own literacy-related knowledge in three areas (knowledge about reading/reading development, phonemic awareness/phonics, and morpheme awareness/structural analysis), graduate teacher-education students completed five tasks intended to measure their actual disciplinary knowledge in these areas. Teachers with high levels of prior…

  5. Current NRC activities related to MQA

    Energy Technology Data Exchange (ETDEWEB)

    Trottier, C.A.; Nellis, D.O. [Nuclear Regulatory Commission, Washington, DC (United States)

    1993-12-31

    The U.S. Nuclear Regulatory Commission`s (NRC`s) interest in measurement quality assurance (MQA) goes back to before 1963, when the Atomic Energy Commission (AEC) published a notice in the Federal Register concerning the need for establishing a Film Dosimetry Calibration Laboratory, and also provided a set of minimum performance criteria to be used by the laboratory in evaluating film dosimetry services used by licensees. The proposed laboratory was not established, but in 1967 the AEC contracted with Battelle`s Pacific Northwest Laboratory (PNL) to evaluate film dosimeter performance criteria and provide a basis for establishing a Film Dosimetry Calibration Laboratory if the study showed that it was needed. Then, in 1973, the Conference of Radiation Control Program Directors (CRCPD), concerned with the state of dosimetry processing and the lack of adequate standards, recommended that the National Bureau of Standards (NBS) direct a performance testing program for personnel dosimetry processing services. Later, in 1976, NRC asked PNL to conduct a study to evaluate the four existing performance standards for personnel dosimetry processing. One result of this study was that the HPSSC standard, which later became ANSI N13.11, was recommended as the standard for use in a national dosimetry processing program. The rest is common knowledge. With the support of numerous other federal agencies and the CRCPD, NRC published a regulation, effective in 1988, that required all processors of personnel dosimeters be accredited under the National Voluntary Laboratory Accreditation Program (NVLAP), operated by the NBS, which is now called the National Institute of Standards and Technology (NIST). At present, there are 75 dosimetry processing laboratories accredited under NVLAP. NRC has also been involved in extremity dosimeters, health physics survey instruments, bioassay measurements, electronic personnel dosimeters, and environmental monitoring around nuclear power plants.

  6. Relation Between Organizational Climate and its Dimensions and Knowledge-sharing Behavior among Knowledge Workers

    Directory of Open Access Journals (Sweden)

    Milena Margarita Villamizar Reyes

    2016-06-01

    Full Text Available This study aimed at identifying the relation of organizational climate and its dimensions from the PMCO measuring test for organizational climate (Cardenas & Villamizar, 2008, as cited in Cardenas, Arciniegas y Barrera, 2009 - in knowledge-sharing behavior, which was measured from the psychosocial variables and organizational conditions of knowledge-sharing behavior test (Castañeda y Fernandez, 2007. 100 participants from two types of organizations participated on this study: one of private nature and one public. A correlation of 0.578 between organizational climate and knowledge-sharing behavior was found. When carrying out an analysis of each organization, it was evident that the level of correlation between climate and knowledge-sharing behavior was highly significant in the public organization: There was a reliability level higher to 99%. There was no correlation found between the two variables studied in the private organization -with an r of 0.093 to 95%. As for the dimensions of climate and knowledge-sharing behavior, the results showed that in all public universities (including level of work, which got the lowest relation these are statistically significant to 99.9%. In the private university only a relation to the personal growth dimension of 95% was found.

  7. Lexical knowledge sources for cartography and GIS - development, current status and outlook

    Science.gov (United States)

    Koch, Wolf Günther

    2016-12-01

    Lexical knowledge sources are indispensable for research, education and general information. The transition of the reference works to the digital world has been a gradual one. This paper discusses the basic principles and structure of knowledge presentation, as well as user access and knowledge acquisition with specific consideration of contributions in German. The ideal reference works of the future should be interactive, optimally adapted to the user, reliable, current and quotable.

  8. Relational dynamics in the multi-helices knowledge production system

    DEFF Research Database (Denmark)

    Thai, Thi Minh; Hjortsø, Carsten Nico Portefée

    in an emerging economy. Findings highlight the emergence of a fifth-helices knowledge production system includes the state, science and education, industry, international actors, and society. The system comprises two major segments, one associated with the traditional command economy and characterized......-level dynamics are characterized by political ambidexterity that enables the state to maintain control by privileging traditional science and education constituencies, and at the same time support the transition of the knowledge production system towards international methodology and quality standards through......Drawing on the triple helix framework and organizational institutionalism, this article applies a qualitative research approach to analyze structures, institutional logics, power relations that shape inter-organizational relations and the structuration of a knowledge production system...

  9. Breast-feeding: Current knowledge, attitudes and practices of paediatricians and obstetricians

    Directory of Open Access Journals (Sweden)

    A. Videlefsky

    1996-05-01

    Full Text Available Doctors, as part of the healthcare team, can have a significant impact on the successful initiation and maintenance of breastfeeding. There is a need for ongoing education and intervention programmes to update current knowledge on breastfeeding management.

  10. Preschool Teachers' Beliefs, Knowledge, and Practices Related to Classroom Management

    Science.gov (United States)

    Drang, Debra Michal

    2011-01-01

    This study examined preschool teachers' beliefs, knowledge, and practices related to classroom management. The rationale for researching this topic is based on the role of teachers in the special education referral process, the poor success rate for inclusion for children with disabilities who demonstrate problematic classroom behaviors, and the…

  11. Children's Use of Knowledge of Place in Understanding Social Relations

    Science.gov (United States)

    Harju, Anne

    2013-01-01

    The article explores how children use different types of knowledge of place to make sense of their relations to other children. The participants are children aged 11-12 in a small town in southern Sweden. The methodology used is place mapping with group interviews. A significant outcome is that the children connect emplaced and spatial knowledge…

  12. Knowledge, attitudes and behaviours of adolescents in relation to ...

    African Journals Online (AJOL)

    2009-04-23

    Apr 23, 2009 ... high incidence of teenage pregnancy, alcohol and drug abuse, is of grave concern, ... a Mona K, MBChB student a Mbonisweni AM, MBChB student a Mbulawa N, ... To determine the levels of STI-related knowledge and.

  13. an assessment of knowledge of farming-related hazards and ...

    African Journals Online (AJOL)

    Tersor

    and long distance trekking to farm (mean=1114.08) were the top known hazards among farmers in the ... knowledge and practices of farm related occupational hazards in the study area. ... is also very important in this process since it plays.

  14. Bridging dynamic global sourcing relations with knowledge governance

    DEFF Research Database (Denmark)

    Jørgensen, Claus; Friis, Ole Uhrskov

    2016-01-01

    The purpose of the paper is to explore how knowledge governance can be used for bridging global sourcing relations in the struggle to avoid the erosion of firm capabilities. The paper is based on longitudinal case studies of two Danish enterprises competing in the highly globalized textile industry....

  15. Reading Thematically Related Texts to Develop Knowledge and Comprehension

    Science.gov (United States)

    Gelzheiser, Lynn; Hallgren-Flynn, Laura; Connors, Margaret; Scanlon, Donna

    2014-01-01

    When literacy instruction uses books selected on the basis of thematic content, it can foster the attainment of literacy goals while developing readers' knowledge. This paper provides a rationale for the use of thematically-related texts in literacy instruction and describes some thematic units that have been a part of literacy intervention…

  16. Framework for product knowledge and product related knowledge which supports product modelling for mass customization

    DEFF Research Database (Denmark)

    Riis, Jesper; Hansen, Benjamin Loer; Hvam, Lars

    2003-01-01

    The article presents a framework for product knowledge and product related knowledge which can be used to support the product modelling process which is needed for developing IT systems. These IT systems are important tools for many companies when they aim at achieving mass customization and pers......The article presents a framework for product knowledge and product related knowledge which can be used to support the product modelling process which is needed for developing IT systems. These IT systems are important tools for many companies when they aim at achieving mass customization...... on experience from product modelling projects in several companies. Among them for example companies manufacturing electronic switchboards, spray dryer systems and air conditioning equipment. The framework is divided into three views: the product knowledge view, the life phase system view and the transformation...... process view (“the meeting”). The persons (rolls) involved in the product modelling process are for example: domain experts, change managers, model managers, project leaders, technical facilitators, process managers and software programmers. They need a framework during the product modelling process...

  17. Disease Related Knowledge Summarization Based on Deep Graph Search

    Directory of Open Access Journals (Sweden)

    Xiaofang Wu

    2015-01-01

    Full Text Available The volume of published biomedical literature on disease related knowledge is expanding rapidly. Traditional information retrieval (IR techniques, when applied to large databases such as PubMed, often return large, unmanageable lists of citations that do not fulfill the searcher’s information needs. In this paper, we present an approach to automatically construct disease related knowledge summarization from biomedical literature. In this approach, firstly Kullback-Leibler Divergence combined with mutual information metric is used to extract disease salient information. Then deep search based on depth first search (DFS is applied to find hidden (indirect relations between biomedical entities. Finally random walk algorithm is exploited to filter out the weak relations. The experimental results show that our approach achieves a precision of 60% and a recall of 61% on salient information extraction for Carcinoma of bladder and outperforms the method of Combo.

  18. Current knowledge on the genetics of autism and propositions for future research.

    Science.gov (United States)

    Bourgeron, Thomas

    2016-01-01

    Autism spectrum disorders (ASD) are a heterogeneous group of neuropsychiatric disorders characterized by problems in social communication, as well as by the presence of restricted interests, stereotyped and repetitive behaviours. In the last 40years, genetic studies have provided crucial information on the causes of ASD and its diversity. In this article, I will first review the current knowledge on the genetics of ASD and then suggest three propositions to foster research in this field. Twin and familial studies estimated the heritability of ASD to be 50%. While most of the inherited part of ASD is captured by common variants, our current knowledge on the genetics of ASD comes almost exclusively from the identification of highly penetrant de novo mutations through candidate gene or whole exome/genome sequencing studies. Approximately 10% of patients with ASD, especially those with intellectual disability, are carriers of de novo copy-number (CNV) or single nucleotide variants (SNV) affecting clinically relevant genes for ASD. Given the function of these genes, it was hypothesized that abnormal synaptic plasticity and failure of neuronal/synaptic homeostasis could increase the risk of ASD. In addition to these discoveries, three propositions coming from institutions, researchers and/or communities of patients and families can be made to foster research on ASD: (i) to use more dimensional and quantitative data than diagnostic categories; (ii) to increase data sharing and research on genetic and brain diversity in human populations; (iii) to involve patients and relatives as participants for research. Hopefully, this knowledge will lead to a better diagnosis, care and integration of individuals with ASD.

  19. On the Relationships between (Relatively) Advanced Mathematical Knowledge and (Relatively) Advanced Problem-Solving Behaviours

    Science.gov (United States)

    Koichu, Boris

    2010-01-01

    This article discusses an issue of inserting mathematical knowledge within the problem-solving processes. Relatively advanced mathematical knowledge is defined in terms of "three mathematical worlds"; relatively advanced problem-solving behaviours are defined in terms of taxonomies of "proof schemes" and "heuristic behaviours". The relationships…

  20. On the Relationships between (Relatively) Advanced Mathematical Knowledge and (Relatively) Advanced Problem-Solving Behaviours

    Science.gov (United States)

    Koichu, Boris

    2010-01-01

    This article discusses an issue of inserting mathematical knowledge within the problem-solving processes. Relatively advanced mathematical knowledge is defined in terms of "three mathematical worlds"; relatively advanced problem-solving behaviours are defined in terms of taxonomies of "proof schemes" and "heuristic behaviours". The relationships…

  1. Crucial knowledge gaps in current understanding of climate change impacts on coral reef fishes

    KAUST Repository

    Wilson, S. K.

    2010-02-26

    Expert opinion was canvassed to identify crucial knowledge gaps in current understanding of climate change impacts on coral reef fishes. Scientists that had published three or more papers on the effects of climate and environmental factors on reef fishes were invited to submit five questions that, if addressed, would improve our understanding of climate change effects on coral reef fishes. Thirty-three scientists provided 155 questions, and 32 scientists scored these questions in terms of: (i) identifying a knowledge gap, (ii) achievability, (iii) applicability to a broad spectrum of species and reef habitats, and (iv) priority. Forty-two per cent of the questions related to habitat associations and community dynamics of fish, reflecting the established effects and immediate concern relating to climate-induced coral loss and habitat degradation. However, there were also questions on fish demographics, physiology, behaviour and management, all of which could be potentially affected by climate change. Irrespective of their individual expertise and background, scientists scored questions from different topics similarly, suggesting limited bias and recognition of a need for greater interdisciplinary and collaborative research. Presented here are the 53 highest-scoring unique questions. These questions should act as a guide for future research, providing a basis for better assessment and management of climate change impacts on coral reefs and associated fish communities.

  2. Crucial knowledge gaps in current understanding of climate change impacts on coral reef fishes.

    Science.gov (United States)

    Wilson, S K; Adjeroud, M; Bellwood, D R; Berumen, M L; Booth, D; Bozec, Y-Marie; Chabanet, P; Cheal, A; Cinner, J; Depczynski, M; Feary, D A; Gagliano, M; Graham, N A J; Halford, A R; Halpern, B S; Harborne, A R; Hoey, A S; Holbrook, S J; Jones, G P; Kulbiki, M; Letourneur, Y; De Loma, T L; McClanahan, T; McCormick, M I; Meekan, M G; Mumby, P J; Munday, P L; Ohman, M C; Pratchett, M S; Riegl, B; Sano, M; Schmitt, R J; Syms, C

    2010-03-15

    Expert opinion was canvassed to identify crucial knowledge gaps in current understanding of climate change impacts on coral reef fishes. Scientists that had published three or more papers on the effects of climate and environmental factors on reef fishes were invited to submit five questions that, if addressed, would improve our understanding of climate change effects on coral reef fishes. Thirty-three scientists provided 155 questions, and 32 scientists scored these questions in terms of: (i) identifying a knowledge gap, (ii) achievability, (iii) applicability to a broad spectrum of species and reef habitats, and (iv) priority. Forty-two per cent of the questions related to habitat associations and community dynamics of fish, reflecting the established effects and immediate concern relating to climate-induced coral loss and habitat degradation. However, there were also questions on fish demographics, physiology, behaviour and management, all of which could be potentially affected by climate change. Irrespective of their individual expertise and background, scientists scored questions from different topics similarly, suggesting limited bias and recognition of a need for greater interdisciplinary and collaborative research. Presented here are the 53 highest-scoring unique questions. These questions should act as a guide for future research, providing a basis for better assessment and management of climate change impacts on coral reefs and associated fish communities.

  3. HIV-related neuropathy: current perspectives

    Directory of Open Access Journals (Sweden)

    Schütz SG

    2013-09-01

    Full Text Available Sonja G Schütz, Jessica Robinson-Papp Department of Neurology, Mount Sinai School of Medicine, New York, NY, USA Abstract: Distal symmetric polyneuropathy (DSP related to human immunodeficiency virus (HIV is one of the most common neurologic complications of HIV, possibly affecting as many as 50% of all individuals infected with HIV. Two potentially neurotoxic mechanisms have been proposed to play a crucial role in the pathogenesis of HIV DSP: neurotoxicity resulting from the virus and its products; as well as adverse neurotoxic effects of medications used in the treatment of HIV. Clinically, HIV DSP is characterized by a combination of signs and symptoms that include decreased deep tendon reflexes at the ankles and decreased sensation in the distal extremities as well as paresthesias, dysesthesias, and pain in a symmetric stocking–glove distribution. These symptoms are generally static or slowly progressive over time, and depending on the severity, may interfere significantly with the patient's daily activities. In addition to the clinical picture, nerve conduction studies and skin biopsies are often pursued to support the diagnosis of HIV DSP. Anticonvulsants, antidepressants, topical agents, and nonspecific analgesics may help relieve neuropathic pain. Specifically, gabapentin, lamotrigine, pregabalin, amitriptyline, duloxetine, and high-dose topical capsaicin patches have been used in research and clinical practice. Further research is needed to elucidate the pathogenesis of HIV DSP, thus facilitating the development of novel treatment strategies. This review discusses the epidemiology, pathophysiology, clinical findings, diagnosis, and management of DSP in the setting of HIV. Keywords: neuropathy, human immunodeficiency virus, acquired immunodeficiency syndrome, AIDS, distal symmetric polyneuropathy, DSP, pain

  4. A relational data-knowledge base system and its potential in developing a distributed data-knowledge system

    Science.gov (United States)

    Rahimian, Eric N.; Graves, Sara J.

    1988-01-01

    A new approach used in constructing a rational data knowledge base system is described. The relational database is well suited for distribution due to its property of allowing data fragmentation and fragmentation transparency. An example is formulated of a simple relational data knowledge base which may be generalized for use in developing a relational distributed data knowledge base system. The efficiency and ease of application of such a data knowledge base management system is briefly discussed. Also discussed are the potentials of the developed model for sharing the data knowledge base as well as the possible areas of difficulty in implementing the relational data knowledge base management system.

  5. Advanced Knowledge Work and Stress-related Symptoms : Epidemiology and Clinical Intervention Studies

    OpenAIRE

    Wiholm, Clairy

    2006-01-01

    Well educated knowledge workers are a growing group of the work force. Little research has been conducted on this group regarding possible work-related health symptoms, as well as interventions in order to reduce work-related stress. This thesis describes the current work-related symptoms and potential risk and salutogenic, i.e. protective factors, associated with these symptoms among software and system designers in a high tech company in Sweden. A stress management intervention program was...

  6. 医院管理层和相关临床科室营养知识现状调查%Investigation on the current situation of mastery of knowledge of nutrition of hospital management staff and medical personnel of related clinical departments

    Institute of Scientific and Technical Information of China (English)

    陈立勇; 张洁; 孟妍

    2011-01-01

    目的:调查医院管理层和相关临床科室营养科普知识、营养专业知识、临床营养知识的现状.方法:选择山东省30所医院为研究对象,设计调查表,请各所医院的医院管理层和相关临床科室医护人员进行营养学知识问卷调查.调查内容包括一般情况,营养科普知识、营养专业知识、临床营养知识和知识来源及应用.结果:医院管理层和相关临床科室医护人员的临床营养学知识普遍不足,营养科普知识掌握好于营养专业知识和临床营养知识(P<0.01);不同类别医院之间知识掌握情况有显著性差异(P<0.01).不同专业之间知识,掌握有差异,内外科明显优于其他科室(P<0.05).不同职称的医生之间营养学知识答题得分差异无显著性.不同学历之间营养知识的掌握有差异,博士与硕士高于本科及以下学历(P<0.01).结论:我省三级医院管理群体及普通医护人员基础营养、临床营养知识不足,建议医学院校适当增加营养学课程学时,适当增加培训以提高医护人员营养学知识水平及整体医疗素质.%Objective: To investigate the current situation of mastery of popular knowledge of nutrition, professional and clinical knowledge of nutrition of hospital management staff and medical personnel of the related clinical departments. Methods:30 hospitals in Shandong province were selected as the research objects, and hospital management staff and medical personnel of the related clinical departments were investigated by the designed questionnaire which included general information, the channel to gain the popular knowledge of nutrition, professional and clinical knowledge of nutrition and its application. Results: The mastery of clinical knowledge of nutrition of hospital management staff and medical personnel is inadequate. The command of popular knowledge of nutrition was better than that of professional and clinical knowledge of nutrition (P <0. 01 ); the

  7. What's Past Is Prologue: Relations between Early Mathematics Knowledge and High School Achievement

    Science.gov (United States)

    Watts, Tyler W.; Duncan, Greg J.; Siegler, Robert S.; Davis-Kean, Pamela E.

    2014-01-01

    Although previous research has established the association between early-grade mathematics knowledge and later mathematics achievement, few studies have measured mathematical skills prior to school entry, and few have investigated the predictive power of early gains in mathematics ability. The current paper relates mathematical skills measured at…

  8. Parenting Practices and Adolescent Drug-Related Knowledge, Attitudes, Norms and Behavior

    Science.gov (United States)

    Macaulay, Araxi P.; Griffin, Kenneth W.; Gronewold, Elizabeth; Williams, Christopher; Botvin, Gilbert J.

    2005-01-01

    The current study explored the relationships between parenting practices and adolescent drug use. Suburban middle school students (N = 2129) completed surveys that included measures of perceived parental monitoring, discipline and setting an anti-drug message as well as measures of drug-related knowledge, attitudes and peer norms. Results…

  9. Invasive Carassius Carp in Georgia: Current state of knowledge and future perspectives

    Directory of Open Access Journals (Sweden)

    Bella JAPOSHVILI, Levan MUMLADZE, Fahrettin KÜÇÜK

    2013-12-01

    Full Text Available In Georgia, crucian carp Carassius carassius (Linnaeus, 1758 was known from only one locality after Kesslers record (1877–1878 with no new findings until 1985. Since then C. carassius rapidly and simultaneously invaded almost all water bodies of Georgia. In 2004, it was for the first time noted that this invasive Carassius sp. could not be a C. Carassius, but was a form of Carassius gibelio (Bloch, 1792. However no further data is available about this invasive species in Georgia. The aim of the present study was to investigate taxonomic status of Carassius sp. in Georgia using mtDNA phylogenetic analyses and morphometric study of truss network system. Genetic analysis revealed that invasive Carassius sp. is closely related to the C. gibelio from Turkey and other countries. In contrast, morphometrically Carassius sp. from Georgia can be easily differentiated from those of Turkey indicating high intraspecific variability. This is the first time discussion on the current knowledge of the present distribution of invasive carp in Georgia with identifying current problems and future research directions needed [Current Zoology 59 (6: 732–739, 2013].

  10. The relationship between chiropractor required and current level of business knowledge.

    Science.gov (United States)

    Ciolfi, Michael Anthony; Kasen, Patsy Anne

    2017-01-01

    Chiropractors frequently practice within health care systems requiring the business acumen of an entrepreneur. However, some chiropractors do not know the relationship between the level of business knowledge required for practice success and their current level of business knowledge. The purpose of this quantitative study was to examine the relationship between chiropractors' perceived level of business knowledge required and their perceived level of current business knowledge. Two hundred and seventy-four participants completed an online survey (Health Care Training and Education Needs Survey) which included eight key business items. Participants rated the level of perceived business knowledge required (Part I) and their current perceived level of knowledge (Part II) for the same eight items. Data was collected from November 27, 2013 to December 18, 2013. Data were analyzed using Spearman's ranked correlation to determine the statistically significant relationships for the perceived level of knowledge required and the perceived current level of knowledge for each of the paired eight items from Parts I and II of the survey. Wilcoxon Signed Ranks Tests were performed to determine the statistical difference between the paired items. The results of Spearman's correlation testing indicated a statistically significant (p ethical, (e) managerial decisions, and (f) operations. Wilcoxon Signed Ranks testing indicated a significant difference for three paired items: strategic management; marketing and; legal and ethical. The results suggest that relationships exist for the majority of business items (6 of 8) however a statistically difference was demonstrated in only three of the paired business items. The implications of this study for social change include the potential to improve chiropractors' business knowledge and skills, enable practice success, enhance health services delivery and positively influence the profession as a viable career.

  11. HPV-Related Knowledge Among Dentists and Dental Hygienists.

    Science.gov (United States)

    Daley, Ellen M; Thompson, Erika L; Vamos, Cheryl A; Griner, Stacey B; Vazquez-Otero, Coralia; Best, Alicia L; Kline, Nolan S; Merrell, Laura K

    2016-12-30

    Dental providers, such as dentists and dental hygienists, play an important role in HPV-related oropharyngeal cancer prevention. Dental professional organizations recommend dental providers educate patients about HPV and oral cancers. The objective of this study was to assess HPV knowledge among dental providers. Dentists (n = 36) and dental hygienists (n = 146) attending a professional conference completed a continuing education post-test survey, which included socio-demographics, an HPV knowledge scale, and measure of HPV discussion with patients ("no," "yes," and "yes, but only with some patients"). Chi-square tests, t tests, and ANOVA tests were used for this analysis. Although dental hygienists (35.4%) reported less discussion with patients about HPV than dentists (52.8%), these differences were not significant. The mean knowledge score was 24.7 (SD = 3.8) with no significant differences by profession. Among dentists, knowledge did not significantly differ by discussion category (p = 0.28). In contrast, dental hygienists who did not discuss HPV with patients had significantly lower mean knowledge scores (mean = 23.4) than those who discussed with patients (mean = 26.5, p HPV, HPV in men, and curability. Specifically, participants incorrectly answered that HPV can affect a women's ability to get pregnant (81.9%), that one can never get rid of HPV once they have it (69.2%), and that HPV can cause herpes (43.4%). This study identified HPV knowledge deficits among dental providers. Given the recommendation for dental providers to discuss HPV prevention with their patients, additional education and training on this emerging topic may benefit these professionals.

  12. Survival in extreme environments – on the current knowledge of adaptations in tardigrades

    DEFF Research Database (Denmark)

    Møbjerg, Nadja; Halberg, Kenneth Agerlin; Jørgensen, Aslak

    2011-01-01

    of the tardigrades and highlight species that are currently used as models for physiological and molecular investigations. Tardigrades are uniquely adapted to a range of environmental extremes. Cryptobiosis, currently referred to as a reversible ametabolic state induced by e.g. desiccation, is common especially...... to below )20 C, presumably relying on efficient DNA repair mechanisms and osmoregulation. This review summarizes the current knowledge on adaptations found among tardigrades, and presents new data on tardigrade cell numbers and osmoregulation....

  13. Malaria related knowledge, practices and behaviour of people in Nepal

    Directory of Open Access Journals (Sweden)

    A.B. Joshi

    2008-02-01

    Full Text Available Background & objectives: The information on malaria related knowledge, practices and behaviour of the people of Nepal living in malaria endemic areas are essential to develop behavioural change communication messages and for producing policy to prevent and control malaria in the country. The objective of this study was to assess knowledge, practices and behaviour of the people living in malaria endemic districts and relate with malaria control policy in Nepal. Methods: The paper utilizes data from a cross-sectional study of 1330 households conducted during December 2004 to April 2005 in rural areas of Jhapa, Kailali and Kanchanpur districts. The method used includes structured questionnaire and focus group discussions. Results: The results revealed that 40% respondents were illiterates. Eighty-six percent respondents have heard about malaria but only 50% responded fever with chills as the sign and symptom of malaria. Seventy-three percent responded that mosquito bite causes malaria transmission and 74% respondents considered that malaria is the fatal disease but very few have knowledge that the treatment of malaria in time can save life. More than 50% did not have information on availability of free treatment of malaria in Nepal. Still 16% were found consulting traditional healers for the treatment. The outside sleeping habit was found in almost one fourth of the population mainly in summer season indicating no knowledge about prevention of malaria. Although bednet use practice was higher, only 4% had knowledge on insecticide impregnated bednets and 23% of them practicing it. Issues regarding the proper and regular use of bednets, the quality of the bednet and use of free treatment provided by the government, since these districts are reporting high incidence of malaria.Interpretation & conclusion: Health education must be taken into account for communities in malaria endemic areas to produce desired outcomes in malaria control.

  14. Tiger Beetles' (Coleoptera: Carabidae, Cicindelinae) pupal stage: current state of knowledge and future perspectives.

    Science.gov (United States)

    Roza, André S; Mermudes, José R M

    2017-01-26

    The tiger beetles (Carabidae: Cicindelinae) include about 2,822 species and 120 genera around the world. They are one of the most widely studied families of Coleoptera. However, the knowledge about their immature stages is incipient and usually restricted to the larval stages. Pupal characteristics have been among the most ignored aspects of tiger beetle biology. Here we compile and update the current knowledge of tiger beetle pupae.

  15. Analysis on Current Status of Influenza A(H1N1)Knowledge and Related Determinants Among 2,311 Residents in Hunan%湖南省2311名居民甲型H1N1流感知识现状及其影响因素分析

    Institute of Scientific and Technical Information of China (English)

    曹仲辉; 徐小生; 王五红; 凌建军; 张艳; 罗家有

    2011-01-01

    目的 了解湖南省居民甲型H1N1流感知识现状及其影响因素,为开展社区居民甲型H1N1流感知识健康教育提供科学依据.方法 采用问卷调查的方式,对2311名社区居民进行调查,采用Logistic回归分析方法 筛选甲型H1N1流感知识现况的影响因素.结果 被调查对象中,获取甲型H1N1流感知识的主要途径为电视86.6%、报纸53.3%和网络51.9%;公众对于甲型H1N1流感知识的总知晓率为36.4%,其中"是否知道甲型H1N1流感"的知晓率为93.3%;甲型H1N1流感的主要临床表现、潜伏期和传播途径,分别为52.9%、43.5%和38.5%;而甲型H1N1流感的治疗方式、预防主要措施、传染期和抗病毒药物分别为21.9%、20.8%、17.1%和3.6%;多因素Logistic回归分析结果 显示:性别、职业和文化程度与甲型H1N1流感知识得分有关.结论 居民甲型H1N1流感知识水平有待提高,应采取针对性健康教育干预,以提高社区居民应对甲型H1N1流感的能力.%Objective To investigate the current situation of influenza A (H1N1) knowledge end the related determinants among the residents in Hunan Province, and to provide the evidence for developing the health education about influenza A (H1N1). Methods Totally 2,311 randomly selected residents were surveyed by a standard questionnaire. Logistic regression models were used to screen the determinants on influenza A (H1N1) knowledge. Results The main channels of acquiring knowledge about influenza A (H1N1) were television (86.6%), newspapers (53.3%) and intemet (51.9%). The total awareness rate of knowledge about influenza A (H1N1) was 36.4%, of which the awareness rate of cognition about influenzaA (H1N1) was 93.3%. The clinical symptoms, latent period and transmission routes of influenza A (H1N1) were 52.9%, 43.5% and 38.5%, respectively. The therapy, preventive measures, infective period and antiviral drug were 21.9%, 20.8%, 17.1% and 3.6%, respectively. Data from

  16. Relational dynamics in the multi-helices knowledge production system

    DEFF Research Database (Denmark)

    Thai, Thi Minh; Hjortsø, Carsten Nico Portefée

    in an emerging economy. Findings highlight the emergence of a fifth-helices knowledge production system includes the state, science and education, industry, international actors, and society. The system comprises two major segments, one associated with the traditional command economy and characterized...... by institutional control that reproduces an ill-adopted and less transparent system based on systemic power. At the border of this system, a marketand quality-oriented segment emerges through marked-oriented evolution and collaborative co-evolution processes driven by institutional agency. The system...... relational mechanisms such as cooperation, harmonization, and partnership. Our research shows that the proposed framework offers a valuable basis for deriving realistic policy and program recommendations to guide national and international actors in designing interventions and collaboration within knowledge...

  17. Creating healthy work in small enterprises - from understanding to action:Summary of current knowledge

    OpenAIRE

    Stephen, legg; Ian S., laird; Olsen, Kirsten Bendix; Hasle, Peter

    2014-01-01

    Although much is known about small and medium enterprises (SMEs), our current knowledge and understanding of occupational health and safety (OHS) and the work environment in SMEs is limited. Far less is known about how SMEs put our knowledge of OSH into action. In short, how do we create healthy work and healthy lives as well as ‘healthy business' in SMEs? The present paper, which also acts as an editorial for this special issue, addresses these questions by providing a summary of current kno...

  18. Poverty and health disparities for American Indian and Alaska Native children: current knowledge and future prospects.

    Science.gov (United States)

    Sarche, Michelle; Spicer, Paul

    2008-01-01

    This report explores the current state of knowledge regarding inequalities and their effect on American Indian and Alaska Native children, underscoring gaps in our current knowledge and the opportunities for early intervention to begin to address persistent challenges in young American Indian and Alaska Native children's development. This overview documents demographic, social, health, and health care disparities as they affect American Indian and Alaska Native children, the persistent cultural strengths that must form the basis for any conscientious intervention effort, and the exciting possibilities for early childhood interventions.

  19. AIDS-related Knowledge, Condom Usage Among Medical Postgraduates

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Objective To investigate the knowledge about safety/unsafty of sexual acts relating to HIV transmission, levels of embarrassment related to condom and condom usage among medical postgraduates. Methods From August to December, 1998, a self-administered anonymous questionnaire was given to 271 new medical postgraduates from two medical colleges of Beijing and Hebei Province. Results There was a hazy understanding of the protective function of condom from AIDS among medical postgraduates. Only 14.4% medical postgraduates persisted in using condom, and 27.94% had never or almost never used it. The levels of embarrassment about condom were high. The median score was 3.55+0.98. Whether to use condom was related with the attitudes to condom, but not to AIDS. Conclusion There was some misunderstanding about condom and inconsistent condom usage in medical postgraduates. So it is essential to strengthen the sexual health education among them.

  20. Taking stock of current societal, political and academic stakeholders in the Canadian healthcare knowledge translation agenda

    Directory of Open Access Journals (Sweden)

    Scott-Findlay Shannon

    2007-10-01

    Full Text Available Abstract Background In the past 15 years, knowledge translation in healthcare has emerged as a multifaceted and complex agenda. Theoretical and polemical discussions, the development of a science to study and measure the effects of translating research evidence into healthcare, and the role of key stakeholders including academe, healthcare decision-makers, the public, and government funding bodies have brought scholarly, organizational, social, and political dimensions to the agenda. Objective This paper discusses the current knowledge translation agenda in Canadian healthcare and how elements in this agenda shape the discovery and translation of health knowledge. Discussion The current knowledge translation agenda in Canadian healthcare involves the influence of values, priorities, and people; stakes which greatly shape the discovery of research knowledge and how it is or is not instituted in healthcare delivery. As this agenda continues to take shape and direction, ensuring that it is accountable for its influences is essential and should be at the forefront of concern to the Canadian public and healthcare community. This transparency will allow for scrutiny, debate, and improvements in health knowledge discovery and health services delivery.

  1. Exploring knowledge, attitudes, and practices related to alcohol in Mongolia

    DEFF Research Database (Denmark)

    Demaio, Alessandro R; Dugee, Otgontuya; de Courten, Maximilian;

    2013-01-01

    The leading cause of mortality in Mongolia is Non-Communicable Disease. Alcohol is recognised by the World Health Organization as one of the four major disease drivers and so, in order to better understand and triangulate recent national burden-of-disease surveys and to inform policy responses to...... to alcohol consumption in Mongolia, a national Knowledge, Attitudes and Practices survey was conducted. Focusing on Non-Communicable Diseases and their risk factors, this publication explores the alcohol-related findings of this national survey....

  2. Stroke prevention awareness and treatment knowledge among patients' relatives

    Institute of Scientific and Technical Information of China (English)

    Kai Li; Dongcai Yuan

    2008-01-01

    BACKGROUND: Recent research indicates that if a stroke can be effectively treated within three hours, prognosis is improved. Therefore, it is necessary to properly educate stroke patients' relatives about prevention and treatment. OBJECTIVE: To survey and analyze the present awareness of stroke prevention and treatment knowledge among patients' relatives. DESIGN: Cross-sectional study. SETTING: Beijing Hospital and Medical College of Shandong University and Harrison International Peace Hospital, the Affiliated Hospital of Hebei Medical University.PARTICIPANTS: From May 2005 to November 2006, a "stroke awareness" questionnaire survey was performed in four hospitals, including Harrison International Peace Hospital in Hengshui City (third class, first grade), Fucheng County People's Hospital (second class, first grade), Zaoqiang County Jiahui Countryside Hospital (first class, first grade) and Hengshui City Electricity Industry Bureau Infirmary. The participants provided confirmed consent.METHODS: The "stroke awareness" questionnaire included 10 questions: 1–8 were related to the understanding of stroke, 9 and 10 were related to behavior and attitude towards medical treatment. Demographic information was also collected on each participant, including age, education level, and occupation. Each positive answer accounted for one point. A score of 8 or higher was categorized as "good stroke awareness".MAIN OUTCOME MEASURES: Scores of stroke awareness. RESULTS: A total of 4 000 "stroke awareness" questionnaires were printed and distributed. 3 597 copies were completed and 3 468 were included in the study. ① Relative factors of stroke awareness: The survey demonstrated that the participant's age, educational level, occupation, grade of hospital, and the relationship with the patient had a significant effect on their stroke awareness (P < 0.05–0.01). ② Stroke knowledge: With regard to stroke awareness, 72% subjects did not know the signs indicating the onset of

  3. Encouraging Civic Knowledge and Engagement: Exploring Current Events through a Psychological Lens

    Science.gov (United States)

    Van Camp, Debbie; Baugh, Stacey-Ann

    2016-01-01

    Engagement with political, social, and civil issues is a fundamental component of an educated population, but civic knowledge and engagement are decreasing among adolescents and young adults. A Psychology in Current Events class sought to increase this engagement and key skills such as critical thinking. A one-group pretest-posttest…

  4. Current state of knowledge on aetiology, diagnosis, management, and therapy of myocarditis

    DEFF Research Database (Denmark)

    Caforio, Alida L P; Pankuweit, Sabine; Arbustini, Eloisa

    2013-01-01

    In this position statement of the ESC Working Group on Myocardial and Pericardial Diseases an expert consensus group reviews the current knowledge on clinical presentation, diagnosis and treatment of myocarditis, and proposes new diagnostic criteria for clinically suspected myocarditis and its di...

  5. Content-Related Knowledge of Biology Teachers from Secondary Schools: Structure and Learning Opportunities

    Science.gov (United States)

    Großschedl, Jörg; Mahler, Daniela; Kleickmann, Thilo; Harms, Ute

    2014-01-01

    Teachers' content-related knowledge is a key factor influencing the learning progress of students. Different models of content-related knowledge have been proposed by educational researchers; most of them take into account three categories: content knowledge, pedagogical content knowledge, and curricular knowledge. As there is no consensus about…

  6. Men's knowledge, attitudes and behaviours relating to fertility.

    Science.gov (United States)

    Hammarberg, Karin; Collins, Veronica; Holden, Carol; Young, Kate; McLachlan, Robert

    2017-07-01

    The increasingly common practice in high-income countries to delay childbearing to the fourth and fifth decades of life increases the risk of involuntary childlessness or having fewer children than desired. Older age also increases the risk of age-related infertility, the need for ART to conceive, and obstetric and neonatal complications. Existing research relating to childbearing focusses almost exclusively on women, and in public discourse declining fertility rates are often assumed to be the result of women delaying childbearing to pursue other life goals such as a career and travel. However, evidence suggests that the lack of a partner or a partner willing to commit to parenthood is the main reason for later childbearing. To better understand men's contributions to childbearing decisions and outcomes, the literature pertaining to men's fertility-related knowledge, attitudes and behaviours was reviewed. The electronic databases of Medline, Embase and PsycINFO were searched to identify investigations of men's knowledge, attitudes and behaviours relating to fertility, infertility, reproductive health or childbearing using relevant fertility keyword search terms. Studies were included if they had investigated factors associated with men's fertility-related knowledge, attitudes and behaviours, had been conducted in a high-income country and were published in an English language peer-reviewed journal between January 2005 and August 2016. The search yielded 1349 citations. Of these, 47 papers representing 43 unique studies were included in the review. Where response rate was reported, it ranged between 13 and 94%. Studies varied in terms of research design; inclusion and exclusion criteria; recruitment strategies; adequacy of sample size; recruitment and retention rates and data collection tools. However, findings were consistent and indicate that men almost universally value parenthood, want and expect to become fathers, and aspire to have at least two children. Yet

  7. Cancer-related false knowledge in relatives of cancer patients and the general public.

    Science.gov (United States)

    Turhal, N S; Dane, F; Ulus, C; Sari, S; Senturk, N; Bingol, D

    2010-01-01

    Although there are many myths about cancer in Turkey, there is no study evaluating Turkish public's knowledge about cancer. The goals of our research were to: 1) measure the extent of knowledge of cancer among the Turkish public; 2) determine the differences in extent of cancer-related knowledge between participants who have relatives with cancer and those who do not; and 3) determine the sources of knowledge possessed. Data were obtained from a total of 415 participants (244 female, 171 male), all of them sitting at the Marmara University Faculty of Medicine Hospital (MUFMH) outpatient clinic waiting area for non-cancer-related reasons. Each participant completed a 3-part questionnaire. Appropriate statistical tests were used for comparison. The mean age was 41 years. Of 415 participants, 65.3% stated that they had one or more cancer patient in their immediate family; 70.1% of the participants had a high-school education or greater. The questionnaire showed that, depending on the question, anywhere from 1.7% to 88.5% of the general public possesses some false information; furthermore, the difference in accuracy between relatives of cancer patients and non-relatives was marginal. Only 3 specific questions, related to the following ideas, rendered answers that were statistically significantly different between these 2 groups: breast cancer is only seen in females (p cancer (p cancer is always very painful (p knowledge about cancer was unacceptably high in our cohort. Broader efforts should be made to inform the Turkish public about cancer.

  8. Teachers' literacy-related knowledge and self-perceptions in relation to preparation and experience.

    Science.gov (United States)

    Spear-Swerling, Louise; Brucker, Pamela Owen; Alfano, Michael P

    2005-12-01

    After rating their own literacy-related knowledge in three areas (knowledge about reading/reading development, phonemic awareness/phonics, and morpheme awareness/structural analysis), graduate teacher-education students completed five tasks intended to measure their actual disciplinary knowledge in these areas. Teachers with high levels of prior background (i.e., course preparation and experience) rated themselves as significantly more knowledgeable than did low-background teachers in all areas; high-background participants also significantly outperformed low-background participants on all tasks. However, even high-background teachers scored well below ceiling on the tasks. Regression analyses indicated that teachers' self-perceptions and knowledge were positively influenced by both level of preparation and teaching experience, although the influences on teachers' knowledge differed by task. Teachers had some accurate perceptions of their own knowledge, especially in the area of phonics. Results suggest that differentiating levels of preparation may be useful in studying teacher knowledge, and also support the notion of a substantial gap between research on reading and teacher preparation in reading.

  9. Sea urchin overgrazing of seagrasses: A review of current knowledge on causes, consequences, and management

    Science.gov (United States)

    Eklöf, J. S.; de la Torre-Castro, M.; Gullström, M.; Uku, J.; Muthiga, N.; Lyimo, T.; Bandeira, S. O.

    2008-09-01

    Sea urchins are one of the most common seagrass macro-grazers in contemporary seagrass systems. Occasionally their grazing rates exceed seagrass growth rates, a phenomenon sometimes referred to as overgrazing. Because of a reported increasing frequency of overgrazing events, concomitant with loss of seagrass-associated ecosystem services, it has been suggested that overgrazing is one of the key threats to tropical and subtropical seagrasses. In light of this, we review the current knowledge on causes, consequences, and management of sea urchin overgrazing of seagrasses. Initially we argue that the definition of overgrazing must include scale and impairment of ecosystem services, since this is the de facto definition used in the literature, and will highlight the potential societal costs of seagrass overgrazing. A review of 16 identified cases suggests that urchin overgrazing is a global phenomenon, ranging from temperate to tropical coastal waters and involving at least 11 seagrass and 7 urchin species. Even though most overgrazing events seem to affect areas of enrichment), top-down (reduced predation control due to e.g. overfishing), "side-in" mechanisms (e.g. changes in water temperature) and natural population fluctuations. Based on recent studies, there seems to be fairly strong support for the top-down and bottom-up hypotheses. However, many potential drivers often co-occur and interact, especially in areas with high anthropogenic pressure, suggesting that multiple disturbances—by simultaneously reducing predation control, increasing urchin recruitment and reducing the resistance of seagrasses—could pave the way for overgrazing. In management, the most common response to overgrazing has been to remove urchins, but limited knowledge of direct and indirect effects makes it difficult to assess the applicability and sustainability of this method. Based on the wide knowledge gaps, which severely limits management, we suggest that future research should focus

  10. Developing genomic knowledge bases and databases to support clinical management: current perspectives.

    Science.gov (United States)

    Huser, Vojtech; Sincan, Murat; Cimino, James J

    2014-01-01

    Personalized medicine, the ability to tailor diagnostic and treatment decisions for individual patients, is seen as the evolution of modern medicine. We characterize here the informatics resources available today or envisioned in the near future that can support clinical interpretation of genomic test results. We assume a clinical sequencing scenario (germline whole-exome sequencing) in which a clinical specialist, such as an endocrinologist, needs to tailor patient management decisions within his or her specialty (targeted findings) but relies on a genetic counselor to interpret off-target incidental findings. We characterize the genomic input data and list various types of knowledge bases that provide genomic knowledge for generating clinical decision support. We highlight the need for patient-level databases with detailed lifelong phenotype content in addition to genotype data and provide a list of recommendations for personalized medicine knowledge bases and databases. We conclude that no single knowledge base can currently support all aspects of personalized recommendations and that consolidation of several current resources into larger, more dynamic and collaborative knowledge bases may offer a future path forward.

  11. Toxicological evaluation of microcystins in aquatic fish species: current knowledge and future directions.

    Science.gov (United States)

    Pavagadhi, Shruti; Balasubramanian, Rajasekhar

    2013-10-15

    Microcystins (MCs) are algal toxins produced intracellularly within the algal cells, and are subsequently released into the aquatic systems. An increase in the frequency and intensity of occurrence of harmful algal blooms has directed the global attention towards the presence of MCs in aquatic systems. The effects of MCs on fish have been verified in a number of studies including histological, biochemical and behavioral effects. The toxicological effects of MCs on different organs of fish are related to the exposure route (intraperitoneal injection, feeding or immersion), the mode of uptake (passive or active transport) as well as biotransformation and bioaccumulation capabilities by different organs. This paper reviews the rapidly expanding literature on the toxicological evaluation of MCs in fish from both field studies and controlled laboratory experimental investigations, integrates the current knowledge available about the mechanisms involved in MC-induced effects on fish, and points out future research directions from a cross-disciplinary perspective. In addition, the need to carry out systematic fish toxicity studies to account for possible interactions between MCs and other environmental pollutants in aquatic systems is discussed. Copyright © 2013 Elsevier B.V. All rights reserved.

  12. The Emergence of Knowledge and How it Supports the Memory for Novel Related Information.

    Science.gov (United States)

    Sommer, Tobias

    2017-03-01

    Current theories suggest that memories for novel information and events, over time and with repeated retrieval, lose the association to their initial learning context. They are consolidated into a more stable form and transformed into semantic knowledge, that is, semanticized. Novel, related information can then be rapidly integrated into such knowledge, leading to superior memory. We tested these hypotheses in a longitudinal, 302-day, human functional magnetic resonance imaging study in which participants first overlearned and consolidated associative structures. This phase was associated with a shift from hippocampal- to ventrolateral prefrontal cortex (vlPFC)-mediated retrieval, consistent with semanticization. Next, participants encoded novel, related information whose encoding into the already acquired knowledge was orchestrated by the ventromedial prefrontal cortex. Novel related information exhibited reduced forgetting compared with novel control information, which corresponded to a faster shift from hippocampal- to vlPFC-mediated retrieval. In sum, the current results suggest that memory for novel information can be enhanced by anchoring it to prior knowledge via acceleration of the processes observed during semanticization. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  13. Galictis cuja (Mammalia: an update of current knowledge and geographic distribution

    Directory of Open Access Journals (Sweden)

    Daniela A. Poo-Muñoz

    2014-09-01

    Full Text Available The lesser grison (Galictis cuja is one of the least-known mustelids in the Neotropics, despite its broad range across South America. This study aimed to explore current knowledge of the distribution of the species to identify gaps in knowledge and anticipate its full geographic distribution. Eighty-nine articles have mentioned G. cuja since 1969, but only 13 focused on the species. We generated a detailed model of the species' potential distribution that validated previous maps, but with improved detail, supporting previous southernmost records, and providing a means of identifying priority sites for conservation and management of the species.

  14. Relating Agulhas leakage to the Agulhas Current retroflection location

    NARCIS (Netherlands)

    van Sebille, E.|info:eu-repo/dai/nl/304831921; Barron, N.; Biastoch, A.; van Leeuwen, P.J.|info:eu-repo/dai/nl/102655758; Vossepoel, F.; de Ruijter, W.P.M.|info:eu-repo/dai/nl/068476760

    2009-01-01

    The relation between the Agulhas Current retroflection location and the magnitude of Agulhas leakage, the transport of water from the Indian to the Atlantic Ocean, is investigated in a high-resolution numerical ocean model. Sudden eastward retreats of the Agulhas Current retroflection loop are

  15. The current-phase relation in HTS Josephson junctions

    Science.gov (United States)

    Il'ichev, E.; Zakosarenko, V.; Ijsselsteijn, R. P. J.; Schultze, V.; Meyer, H.-G.; Hoenig, H. E.

    The current-phase relation of YBa2Cu3O7-x step-edge as well as 24° and 45° grain boundary Josephson junctions has been investigated experimentally. The junctions were incorporated into a washer-shaped superconducting ring with inductance L≈80-300 pH. The ring was inductively coupled to a tank circuit with a resonance frequency 9…40 MHz. The current-phase relation was obtained from the measurement of the impedance of the phase-biased junction. It is shown, that experimentally observed deviations from harmonic behavior of the apparent current-phase relation for step-edge and 24° grain boundary junctions can be explained by the influence of thermal noise. The current-phase relation of 45° grain boundary junctions was found to be extremely non-harmonic. The reasons of this unusual behavior are discussed.

  16. 上海市杨浦区社区居民灾难医学知识现状及需求分析%Current situation and training needs of disaster medicine-related knowledge in community-based populations in Yangpu district of Shanghai

    Institute of Scientific and Technical Information of China (English)

    韩雪; 张蓉; 曹广文; 蒲蕊; 丁一波; 石韶俊; 杜琰; 李自雄; 刘文斌; 张宏伟; 谢梦

    2015-01-01

    Objective] To explore disaster response capability and the vulnerability as well as the current level and training needs of disaster medicine knowledge in urban populations . [ Methods] Five communities in Yangpu District of Shanghai were randomly enrolled in this study .The study populations were then stratified by age groups .A total of 1700 residents were recruited , 1643 of which completed a structured questionnaire designed by the investigators . [ Results] Eight-nine percent of the residents be-lieved the importance of understanding disaster medicine -related knowledge .The correct answer rates of “pro-tective measures of nuclear leakage issues” and “self-rescue measures in a high building fire” reached over 80%;however , the overall correct answer rate of “cardiorespiratory resuscitation operation” was less than 40%.The main channels of community residents accessing disaster medicine knowledge were mainly news -papers, magazines, and internet (52.1%);whereas only 5.3%of them obtained the knowledge from school education .Community residents most liked to obtain “first aid skills”and“basic theory of disaster medicine”through formal lectures (72.4%). [Conclusion] School education lacks disaster-related knowledge , pos-sibly resulting in the fact that community residents have a limited ability to save both oneself and others in disaster .There are significant differences between residents with different education levels .Community resi-dents have limited knowledge of disaster occurrence and development , and lack capabilities of self-rescue and mutual aid .Colleges should increase the contents of disaster medicine education in their curriculum .Disaster education should be enforced in school education .Continued education and simulation of disaster-related knowledge should be regularly offered to community residents to greatly reduce their vulnerability to disasters .%[目的]探索城市居民应对灾难的能力和脆弱性,明确城

  17. Whole dairy matrix or single nutrients in assessment of health effects: current evidence and knowledge gaps.

    Science.gov (United States)

    Thorning, Tanja Kongerslev; Bertram, Hanne Christine; Bonjour, Jean-Philippe; de Groot, Lisette; Dupont, Didier; Feeney, Emma; Ipsen, Richard; Lecerf, Jean Michel; Mackie, Alan; McKinley, Michelle C; Michalski, Marie-Caroline; Rémond, Didier; Risérus, Ulf; Soedamah-Muthu, Sabita S; Tholstrup, Tine; Weaver, Connie; Astrup, Arne; Givens, Ian

    2017-04-12

    Foods consist of a large number of different nutrients that are contained in a complex structure. The nature of the food structure and the nutrients therein (i.e., the food matrix) will determine the nutrient digestion and absorption, thereby altering the overall nutritional properties of the food. Thus, the food matrix may exhibit a different relation with health indicators compared to single nutrients studied in isolation. The evidence for a dairy matrix effect was presented and discussed by an expert panel at a closed workshop, and the following consensus was reached: 1) Current evidence does not support a positive association between intake of dairy products and risk of cardiovascular disease (i.e., stroke and coronary heart disease) and type 2 diabetes. In contrast, fermented dairy products, such as cheese and yogurt, generally show inverse associations. 2) Intervention studies have indicated that the metabolic effects of whole dairy may be different than those of single dairy constituents when considering the effects on body weight, cardiometabolic disease risk, and bone health. 3) Different dairy products seem to be distinctly linked to health effects and disease risk markers. 4) Different dairy structures and common processing methods may enhance interactions between nutrients in the dairy matrix, which may modify the metabolic effects of dairy consumption. 5) In conclusion, the nutritional values of dairy products should not be considered equivalent to their nutrient contents but, rather, be considered on the basis of the biofunctionality of the nutrients within dairy food structures. 6) Further research on the health effects of whole dairy foods is warranted alongside the more traditional approach of studying the health effects of single nutrients. Future diet assessments and recommendations should carefully consider the evidence of the effects of whole foods alongside the evidence of the effects of individual nutrients. Current knowledge gaps and

  18. Consumer attitudes, knowledge, and behavior related to salt consumption in sentinel countries of the Americas

    OpenAIRE

    CLARO, Rafael Moreira; Linders, Hubert; Ricardo,Camila Zancheta; Legetic, Branka; Campbell, Norm R. C.

    2012-01-01

    Objective. To describe individual attitudes, knowledge, and behavior regarding salt intake, its dietary sources, and current food-labeling practices related to salt and sodium in five sentinel countries of the Americas. Methods. A convenience sample of 1 992 adults (>= 18 years old) from Argentina, Canada, Chile, Costa Rica, and Ecuador (approximately 400 from each country) was obtained between September 2010 and February 2011. Data collection was conducted in shopping malls or major comme...

  19. Analysis of the relation between knowledge engineering and knowledge management based on the Nonaka and Takeuchi models

    Directory of Open Access Journals (Sweden)

    Christian Reyes

    2007-07-01

    Full Text Available The use of the Knowledge Management is fundamental in the creation of value within the companies, being at the present time a new form to obtain competitive advantages in specific market. Also, for the process of value creation is necessary to use specifics Information Technologies that they allow to reach the objectives drawn up when implementing a Knowledge Management project. In this sense, one of the more complete and efficient Information Technologies is the Knowledge Based System that as well comprises of the Knowledge Engineering. This article tries to analyze the existing relation between Knowledge Management, a specific model of knowledge creation, the Knowledge Based System and how this Information Technologies play a very important role in the creation, codification and transference of knowledge.

  20. Knowledges

    DEFF Research Database (Denmark)

    Berling, Trine Villumsen

    2012-01-01

    and reflectivism. Bourdieu, on the contrary, lets the challenge to the theory/reality distinction spill over into a challenge to the theory/practice distinction by thrusting the scientist in the foreground as not just a factor (discourse/genre) but as an actor. In this way, studies of IR need to include a focus......Scientific knowledge in international relations has generally focused on an epistemological distinction between rationalism and reflectivism over the last 25 years. This chapter argues that this distinction has created a double distinction between theory/reality and theory/practice, which works...... as a ghost distinction structuring IR research. While reflectivist studies have emphasised the impossibility of detached, objective knowledge production through a dissolution of the theory/reality distinction, the theory/practice distinction has been left largely untouched by both rationalism...

  1. Key tasks in healthcare marketing: assessing importance and current level of knowledge.

    Science.gov (United States)

    Kennett, Pamela A; Henson, Steve W; Crow, Stephen M; Hartman, Sandra J

    2005-01-01

    When examining the healthcare industry, the need for continuing education in internal functions (i.e., HR management) has been documented. However, equally important to success in the healthcare industry are external functions such as marketing. In an expansion of research on internally focused functions, we report findings from an exploratory study designed to examine the perceptions of executives about managerial skill needs in the externally focused area of marketing. Specifically, we examine eight key tasks in marketing and ask executives to rate the level of knowledge required for each and then to assess current, or actual, levels of knowledge in the field. Findings suggest that pricing strategy, product strategy, and segmentation and targeting were the tasks that require the most knowledge for healthcare marketers, and that they do, in fact, perceive various gaps in all of the areas examined. Implications and suggestions for future research are provided.

  2. University and Business Relations: Connecting the Knowledge Economy

    Science.gov (United States)

    Metcalfe, J. Stanley

    2010-01-01

    It is commonplace to say that the modern economy is knowledge based but a moment's reflection points to the vacuity of this notion. For all economies are knowledge based and could not be otherwise. The question is rather how is one kind of knowledge based economy to be distinguished from another? This essay proposes that the answer may lie in…

  3. Transitivity performance, relational hierarchy knowledge and awareness: results of an instructional framing manipulation.

    Science.gov (United States)

    Kumaran, Dharshan; Ludwig, Hans

    2013-12-01

    The transitive inference (TI) paradigm has been widely used to examine the role of the hippocampus in generalization. Here we consider a surprising feature of experimental findings in this task: the relatively poor transitivity performance and levels of hierarchy knowledge achieved by adult human subjects. We focused on the influence of the task instructions on participants' subsequent performance--a single-word framing manipulation which either specified the relation between items as transitive (i.e., OLD-FRAME: choose which item is "older") or left it ambiguous (i.e., NO-FRAME: choose which item is "correct"). We show a marked but highly specific effect of manipulating prior knowledge through instruction: transitivity performance and levels of relational hierarchy knowledge were enhanced, but premise performance unchanged. Further, we show that hierarchy recall accuracy, but not conventional awareness scores, was a significant predictor of inferential performance across the entire group of participants. The current study has four main implications: first, our findings establish the importance of the task instructions, and prior knowledge, in the TI paradigm--suggesting that they influence the size of the overall hypothesis space (e.g., to favor a linear hierarchical structure over other possibilities in the OLD-FRAME). Second, the dissociable effects of the instructional frame on premise and inference performance provide evidence for the operation of distinct underlying mechanisms (i.e., an associative mechanism vs. relational hierarchy knowledge). Third, our findings suggest that a detailed measurement of hierarchy recall accuracy may be a more sensitive index of relational hierarchy knowledge, than conventional awareness score--and should be used in future studies investigating links between awareness and inferential performance. Finally, our study motivates an experimental setting that ensures robust hierarchy learning across participants

  4. Current-Voltage Relations for Electrochemical Thin Films

    CERN Document Server

    Bazant, M Z; Bayly, B J; Bazant, Martin Z.; Chu, Kevin T.

    2004-01-01

    The dc response of an electrochemical thin film, such as the separator in a micro-battery, is analyzed by solving the Poisson-Nernst-Planck equations, subject to boundary conditions appropriate for an electrolytic/galvanic cell. The model system consists of a binary electrolyte between parallel-plate electrodes, each possessing a compact Stern layer, which mediates Faradaic reactions with nonlinear Butler-Volmer kinetics. Analytical results are obtained by matched asymptotic expansions in the limit of thin double layers and compared with full numerical solutions. The analysis shows that (i) decreasing the system size relative to the Debye screening length decreases the voltage of the cell and allows currents higher than the classical diffusion-limited current; (ii) finite reaction rates lead to the important possibility of a reaction-limited current; (iii) the Stern-layer capacitance is critical for allowing the cell to achieve currents above the reaction-limited current; and (iv) all polarographic (current-v...

  5. Current knowledge on helicobacter pylori infection in end stage renal disease patients

    Directory of Open Access Journals (Sweden)

    Khedmat Hossein

    2009-01-01

    Full Text Available Gastric infection with Helicobacter Pylori in end-stage renal disease patients is of rele-vance because of its potential impact on the quality of life as well as morbidity and mortality of patients. Existed data on the issue are controversial, and we attempt in this article to evaluate the available data to approach extended perception of the current knowledge on the epidemiology, relevance, and optimum therapeutic strategies.

  6. Feed Efficiency: An Assessment of Current Knowledge from a Voluntary Subsample of the Swine Industry

    Science.gov (United States)

    Flohr, Josh R.; Tokach, Mike D.; DeRouchey, Joel M.; Goodband, Robert D.; Dritz, Steve S.; Nelssen, Jim L.; Patience, John F.

    2014-01-01

    A voluntary sample of pork producers and advisers to the swine industry were surveyed about feed efficiency. The questionnaire was designed to accomplish three objectives: (a) determine the level of knowledge related to feed efficiency topics, (b) identify production practices used that influence feed efficiency, and (c) identify information gaps…

  7. Triathlon related musculoskeletal injuries: the status of injury prevention knowledge.

    Science.gov (United States)

    Gosling, Cameron McR; Gabbe, Belinda J; Forbes, Andrew B

    2008-07-01

    Triathlon is a popular participation sport that combines swimming, cycling and running into a single event. A number of studies have investigated the incidence of injury, profile of injuries sustained and factors contributing to triathlon injury. This paper summarises the published literature in the context of the evidence base for the prevention of triathlon related injuries. Relevant articles on triathlon injuries were sourced from peer-reviewed English language journals and assessed using the Translating Research into Injury Prevention Practice (TRIPP) framework. This review highlights the significant knowledge gap that exists in the published literature describing the incidence of injury, the profile of injuries sustained and evidence for the prevention of injury in triathlon. Despite the number of studies undertaken to address TRIPP Stages 1 and 2 (injury surveillance, aetiology and mechanism of injury), most triathlon studies have been limited by retrospective designs with substantial, and unvalidated, recall periods, inconsistency in the definitions used for a reportable injury and exposure to injury, or a failure to capture exposure data at all. Overall, the paucity of quality, prospective studies investigating the incidence of injury in triathlon and factors contributing to their occurrence has led to an inability to adequately inform the development of injury prevention strategies (TRIPP Stages 3-6) for this sport, a situation that must be rectified if gains are to be made in reducing the burden of triathlon related injury.

  8. On the relationships between (relatively) advanced mathematical knowledge and (relatively) advanced problem-solving behaviours

    Science.gov (United States)

    Koichu, Boris

    2010-03-01

    This article discusses an issue of inserting mathematical knowledge within the problem-solving processes. Relatively advanced mathematical knowledge is defined in terms of three mathematical worlds; relatively advanced problem-solving behaviours are defined in terms of taxonomies of proof schemes and heuristic behaviours. The relationships between mathematical knowledge and problem-solving behaviours are analysed in the contexts of solving an insight geometry problem, posing algebraic problems and calculus exploration. A particularly knowledgeable and skilled university student was involved in all the episodes. The presented examples substantiate the claim that advanced mathematical knowledge and advanced problem-solving behaviours do not always support each other. More advanced behaviours were observed when the student worked within her conceptual-embodied mathematical world, and less advanced ones when she worked within her symbolic and formal-axiomatic worlds. Alternative explanations of the findings are discussed. It seems that the most comprehensive explanation is in terms of the Principle of Intellectual Parsimony. Implications for further research are drawn.

  9. Pharmaceutical residues in environmental waters and wastewater: current state of knowledge and future research.

    Science.gov (United States)

    Fatta-Kassinos, Despo; Meric, Sureyya; Nikolaou, Anastasia

    2011-01-01

    Pollution from pharmaceuticals in the aquatic environment is now recognized as an environmental concern in many countries. This has led to the creation of an extensive area of research, including among others: their chemical identification and quantification; elucidation of transformation pathways when present in wastewater-treatment plants or in environmental matrices; assessment of their potential biological effects; and development and application of advanced treatment processes for their removal and/or mineralization. Pharmaceuticals are a unique category of pollutants, because of their special characteristics, and their behavior and fate cannot be simulated with other chemical organic contaminants. Over the last decade the scientific community has embraced research in this specific field and the outcome has been immense. This was facilitated by advances in chromatographic techniques and relevant biological assays. Despite this, a number of unanswered questions exist and still there is much room for development and work towards a more solid understanding of the actual consequences of the release of pharmaceuticals in the environment. This review tries to present part of the knowledge that is currently available with regard to the occurrence of pharmaceutical residues in aquatic matrices, the progress made during the last several years on identification of such compounds down to trace levels, and of new, previously unidentified, pharmaceuticals such as illicit drugs, metabolites, and photo-products. It also tries to discuss the main recent findings in respect of the capacity of various treatment technologies to remove these contaminants and to highlight some of the adverse effects that may be related to their ubiquitous existence. Finally, socioeconomic measures that may be able to hinder the introduction of such compounds into the environment are briefly discussed.

  10. Current phase relation in nanowire based Josephson junctions

    Science.gov (United States)

    Szombati, Daniel; Nadj-Perge, Stevan; Geresdi, Attila; Mourik, Vincent; Zuo, Kun; Woerkom, David; Car, Diana; Bakkers, Erik; Kouwenhoven, Leo

    2015-03-01

    Junctions based on small band-gap nanowires are convenient platform for studying Josephson effect in the presence of strong spin-orbit coupling. As predicted by theory, due to the interplay between strong Zeeman interaction and large spin orbing coupling in these nanowires, the critical current and in particular current phase relation exhibits rich set of features in the presence of external magnetic field and electrostatic gating. We study supercurrent transport through Indium Antimonide nanowires contacted using Niobium-Titanium-Nitride leads using both current and phase bias measurements. Our results provide useful insights into superconductor/semiconductor hybrid systems capable of hosting Majorana fermions, potential building blocks for topological quantum computing.

  11. Survey on Current Status of Smoking and Smoking-related Knowledge Among Medical Staff Members of a Hospital in Hunan%湖南省某医院医务人员吸烟现状及相关知识调查

    Institute of Scientific and Technical Information of China (English)

    彭进平; 陈梅英; 卜平元

    2011-01-01

    Objective To explore the prevalence of smoking behavior and the smoking- related knowledge and attitude in medical professionals. Methods We designed a smoking - related questionnaire according to the smoking- related materials. Cluster sampling method was applied to conduct a survey of smoking on 578 medical professionals of a hospital in Hunan in October, 2010. Results The current smoking rate of medical professionals was 19.38 %, and the rate of smoking was 33.64 % in males and 1.56 % in females. There were statistically significant differences in the smoking rates of medical staff members with different gender, age, educational backgrounds and professional titles (P<0.05). As for the smokingrelated knowledge and attitude, medical professionals knew the common hazards, such as pulmonary diseases easily resulted from smoking and passive smoking; but there were still 22.49% medical professionals knew little about the harmful effects of smoking and passive smoking on other organs. Most of the medical professionals thought that smoking was de rigueur and it could relieve the stress. Conclusions Smoking behavior is a serious problem among male medical workers, especially smoking behavior of staff members of medical institutions, which brings negative effects on the surrouling people. It is necessary to enhance the tobacco control in medical institutions and create tobacco-free environment in hospitals so as to be a role model and play a support role in the tobacco control work.%目的 探讨医务人员吸烟行为流行情况以及对吸烟的知识与态度.方法 参照有关资料自行设计调查问卷,采用整群抽样法,于2010年11月对湖南省某医院578名医务人员进行调查.结果 医务人员现在吸烟率为19.38%,其中男性吸烟率为33.64%,女性为1.56%;不同性别、年龄、文化程度与职称的医务人员吸烟率差异均有统计学意义(P<0.05).在对吸烟相关知识与态度方面,医务人员知道吸烟与

  12. Managing player load in professional rugby union: a review of current knowledge and practices.

    Science.gov (United States)

    Quarrie, Kenneth L; Raftery, Martin; Blackie, Josh; Cook, Christian J; Fuller, Colin W; Gabbett, Tim J; Gray, Andrew J; Gill, Nicholas; Hennessy, Liam; Kemp, Simon; Lambert, Mike; Nichol, Rob; Mellalieu, Stephen D; Piscione, Julien; Stadelmann, Jörg; Tucker, Ross

    2017-03-01

    The loads to which professional rugby players are subjected has been identified as a concern by coaches, players and administrators. In November 2014, World Rugby commissioned an expert group to identify the physical demands and non-physical load issues associated with participation in professional rugby. To describe the current state of knowledge about the loads encountered by professional rugby players and the implications for their physical and mental health. The group defined 'load' as it relates to professional rugby players as the total stressors and demands applied to the players. In the 2013-2014 seasons, 40% of professional players appeared in 20 matches or more, and 5% of players appeared in 30 matches or more. Matches account for ∼5-11% of exposure to rugby-related activities (matches, team and individual training sessions) during professional competitions. The match injury rate is about 27 times higher than that in training. The working group surmised that players entering a new level of play, players with unresolved previous injuries, players who are relatively older and players who are subjected to rapid increases in load are probably at increased risk of injury. A mix of 'objective' and 'subjective' measures in conjunction with effective communication among team staff and between staff and players was held to be the best approach to monitoring and managing player loads. While comprehensive monitoring holds promise for individually addressing player loads, it brings with it ethical and legal responsibilities that rugby organisations need to address to ensure that players' personal information is adequately protected. Administrators, broadcasters, team owners, team staff and the players themselves have important roles in balancing the desire to have the 'best players' on the field with the ongoing health of players. In contrast, the coaching, fitness and medical staff exert significant control over the activities, duration and intensity of training

  13. Sensory perception in cetaceans: Part I – Current knowledge about dolphin senses as a representative species

    Directory of Open Access Journals (Sweden)

    Dorothee eKremers

    2016-05-01

    Full Text Available A large part of the literature on sensory perception and behavior in dolphins is devoted to its well-developed vocal and echolocation abilities. In this review, we aim to augment current knowledge by examining the literature on dolphins’ entire Merkwelt (which refers to everything a subject perceives, creating a crucial part of the subject’s Umwelt. We will show that despite extensive knowledge on audition, aspects such as context relatedness, the social function of vocalizations or socio-sexual recognition, remain poorly understood. Therefore, we propose areas for further lines of investigation. Recent studies have shown that the sensory world of dolphins might well be much more diverse than initially thought. Indeed, although underwater and aerial visual systems differ in dolphins, they have both been shown to be important. Much debated electro- and magnetoreception appear to be functional senses according to recent studies. Finally, another neglected area is chemoreception. We will summarize neuroanatomical and physiological data on olfaction and taste, as well as corresponding behavioral evidence. Taken together, we will identify a number of technical and conceptual reasons for why chemosensory data appear contradictory, which is much debated in the literature. In summary, this article aims to provide both an overview of the current knowledge on dolphin perception, but also offer a basis for further discussion and potential new lines of research.

  14. The Role of Special Language in Relation to Knowledge Organization.

    Science.gov (United States)

    Thellefsen, Martin

    2003-01-01

    Suggests that knowledge organization must encompass theories that focus on the more fundamental and less technical view and raises the questions of epistemology and general linguistic theory. Focuses on the meaning aspect of language and the terminological aspect of knowledge organization. Considers theories of terminology, language and meaning,…

  15. Introduction: The Growing Importance of Traditional Forest-Related Knowledge

    Science.gov (United States)

    Ronald L. Trosper; John A. Parrotta

    2012-01-01

    The knowledge, innovations, and practices of local and indigenous communities have supported their forest-based livelihoods for countless generations. The role of traditional knowledge—and the bio-cultural diversity it sustains—is increasingly recognized as important by decision makers, conservation and development organizations, and the scientifi c community. However...

  16. KNOWLEDGE AND ATTITUDES RELATED TO HIV/AIDS AMONG MEDICAL AND ALLIED HEALTH SCIENCES STUDENTS

    Directory of Open Access Journals (Sweden)

    Abhimanyu Singh Chauhan

    2011-12-01

    Full Text Available Background: India estimates third highest number of HIV infections in the world, with about 2.4 million people currently living with HIV/AIDS. Adequately trained and sensitized healthcare professionals can play a vital role in combating this epidemic. Limited studies have explored knowledge and attitudes of medical students relating to HIV/AIDS, particularly in the eastern part of India. Methods: The present cross sectional study explored knowledge and attitudes of first year MBBS, BDS & BPT students of Kalinga Institute of Medical Sciences (KIMS, Bhubaneswar, Odisha on HIV/AIDS using a self-administered questionnaire. Data thus collected were analyzedand relevant statistics were calculated. Knowledge and attitude scores were determined and analysis of variance (ANOVA test was used to examine the equality between the groups. Results: All students scored low on the overall knowledge scale (<10/15. Specifically, knowledgewas low on modes of transmission and treatment. Attitudinal scores in the areas of precautions and need for training on HIV was low for all the three streams.The willingness to treat HIV/AIDS patient was found to be high amongst study participants. Conclusion: There is a need and scope to provide correct and detailed information on HIV/AIDS for new entrants in medical and allied health sciences to help them acquire adequate knowledge and develop appropriate attitudes towards HIV/AIDS.

  17. A linear auroral current-voltage relation in fluid theory

    Directory of Open Access Journals (Sweden)

    J. Vedin

    2004-04-01

    Full Text Available Progress in our understanding of auroral currents and auroral electron acceleration has for decades been hampered by an apparent incompatibility between kinetic and fluid models of the physics involved. A well established kinetic model predicts that steady upward field-aligned currents should be linearly related to the potential drop along the field line, but collisionless fluid models that reproduce this linear current-voltage relation have not been found. Using temperatures calculated from the kinetic model in the presence of an upward auroral current, we construct here approximants for the parallel and perpendicular temperatures. Although our model is rather simplified, we find that the fluid equations predict a realistic large-scale parallel electric field and a linear current-voltage relation when these approximants are employed as nonlocal equations of state. This suggests that the concepts we introduce can be applied to the development of accurate equations of state for fluid simulations of auroral flux tubes.

    Key words. Magnetospheric physics (auroral phenomena; magnetosphere-ionosphere interactions – Space plasma physics (kinetic and MHD theory

  18. Ecology of Urban Bees: A Review of Current Knowledge and Directions for Future Study

    Directory of Open Access Journals (Sweden)

    Gordon W. Frankie

    2009-01-01

    Full Text Available Urban bee ecology is an emerging field that holds promise for advancing knowledge of bee community dynamics and promoting bee conservation. Published studies of bee communities in urban and suburban habitats are fewer than those documenting bees in agricultural and wildland settings. As land lost to urbanization is predicted to increase in coming years the necessity of studying urban bee populations is growing. We reviewed 59 publications on urban bee ecology with the following goals, to assess current knowledge, to highlight areas in need of further research, and to suggest applications of study findings to bee conservation. Identified trends in urban areas included the following, negative correlation between bee species richness and urban development, increase in abundance of cavity-nesters in urban habitats, and scarcity of floral specialists. Future directions for studying urban bee ecology include incorporation of landscape-scale assessments, conducting manipulative experiments and actively designing urban bee habitats.

  19. Increasing Parental Knowledge Related to the Human Papillomavirus (HPV) Vaccine.

    Science.gov (United States)

    Cipriano, Joseph J; Scoloveno, Robert; Kelly, Angela

    2017-08-16

    The purposes of this study were to evaluate parental attitudes toward general vaccination protocols and increase parental knowledge of the human papilloma virus (HPV) vaccine. A nonprobability convenience sample (N = 75) using a pre-/postintervention study design was conducted in a pediatric office in southern New Jersey. The Parental Attitudes Module measured the general disposition toward having children receive any type of vaccine. The HPV Knowledge Survey was a second tool used to specifically measures knowledge of the HPV vaccine. A self-directed computer-based learning was part of the educational intervention. A paired t test showed that HPV Knowledge Survey postintervention scores were significantly higher than HPV Knowledge Survey preintervention scores (t = -10.585, p < .001). The Parental Attitudes Module and the HPV Knowledge Survey pretest showed a positive moderate relationship (rs = .552, p < .001). In the 10 years since the HPV vaccine has been on the market, there is a continued need to increase parental knowledge about the HPV vaccine to close the gap on vaccine nonadherence. A self-directed, computer-based learning tablet appears to be an effective tool to educate parents or legal guardians about the purpose, efficacy, and safety of the HPV vaccine. Copyright © 2017 National Association of Pediatric Nurse Practitioners. Published by Elsevier Inc. All rights reserved.

  20. The current-phase relation in Josephson junctions

    NARCIS (Netherlands)

    Golubov, A.A.; Kupriyanov, M. Yu.; Il'ichev, E.

    2004-01-01

    This review provides a theoretical basis for understanding the current-phase relation (CPhiR) for the stationary (dc) Josephson effect in various types of superconducting junctions. The authors summarize recent theoretical developments with an emphasis on the fundamental physical mechanisms of the d

  1. Relation between the ring current and the tail current during magnetic storms

    Directory of Open Access Journals (Sweden)

    V. V. Kalegaev

    2005-02-01

    Full Text Available We study the dynamics of the magnetospheric large-scale current systems during storms by using three different magnetospheric magnetic field models: the paraboloid, event-oriented, and Tsyganenko T01 models. We have modelled two storm events, one moderate storm on 25-26 June 1998, when Dst reached -120nT and one intense storm on 21-23 October 1999, when Dst dropped to -250nT. We compare the observed magnetic field from GOES 8, GOES 9, and GOES 10, Polar and Geotail satellites with the magnetic field given by the three models to estimate their reliability. All models demonstrated quite good agreement with observations. Since it is difficult to measure exactly the relative contributions from different current systems to the Dst index, we compute the contributions from ring, tail and magnetopause currents given by the three magnetic field models. We discuss the dependence of the obtained contributions to the Dst index in relation to the methods used in constructing the models. All models show a significant tail current contribution to the Dst index, comparable to the ring current contribution during moderate storms. The ring current becomes the major Dst source during intense storms.

  2. Survey on AIDS related knowledge and attitude among married people of childbearing age in China

    Institute of Scientific and Technical Information of China (English)

    Li Ying; Cheng Yi-min; Huang Na; Guo Xin; Wu Jun-qing; Ru Xiao-mei

    2005-01-01

    Objective: To learn about the current circumstances surrounding AIDS related knowledge, attitudes and relevant influential factors, and to provide recommendations for HIV/AIDS prevention and control.Methods: A cross sectional study was designed by the cluster sampling method, and a self-administered, closed, and anonymous questionnaire was administered. There were a total of 4,800 married people of childbearing age, from six counties, during the period November through December, 2003.Results: There were 4,693 valid questionnaires and the validity rate was 97.78%. The general correct rate of AIDS knowledge of the respondents was 63.60%. Factors such as sex, age, place of registered permanent residence and different areas had influence on the level of AIDS knowledge. Respondents knew more about AIDS transmission related knowledge than non-transmission related knowledge. Only 30.6% of respondents had heard about volunteer counseling and testing(VCT)of AIDS, and just 8.5% of them thought that they had the possibility of being infected with HIV/AIDS, 64.5% of participants were afraid of AIDS, 66.5% of them thought that HIV positive people should be quarantined, 74.1% of them held that HIV positive people should be forbidden to go to public places, and they would not like to have dinner (68.8%), shake hands (67.8%), or work (63.4%)with HIV positive people. Respondents of different sex, registered permanent residence, education and living places had different attitudes towards HIV/AIDS.Conclusion: The AIDS knowledge level of respondents is below the goal of 75% up to 2005 brought forward by National AIDS Office of China. It is very important to strengthen the Information, Education, Communication (IEC) on AIDS non-transmission related knowledge among married people of childbearing age, especially those who are younger, lower educated and female. Furthermore, the knowledge about VCT should be publicized. More than half of the respondents have negative attitudes towards

  3. Knowledge Cities and Transport Sustainability: The Link between the Travel Behavior of Knowledge Workers and Car-Related Job Perks

    DEFF Research Database (Denmark)

    Frenkel, Amnon; Bendit, Edward; Kaplan, Sigal

    2014-01-01

    from a survey among knowledge workers in Tel-Aviv. Results show that car-related job perks are associated with (1) high annual kilometrage, (2) increased commute by car, (3) long commute travel times, (4) high trip chaining frequency, and (5) many long-distance leisure trips. Results suggest......This study analyzes the linkage between the travel behavior of knowledge workers and car-related job perks. The importance of this issue derives from the tendency of knowledge economy to concentrate in highly populated metropolitan regions. The analyzed data comprise 750 observations, retrieved...

  4. Atmospheric transport and deposition of pesticides: An assessment of current knowledge

    DEFF Research Database (Denmark)

    Pul, W.A.J. van; Bidleman, T.F.; Brorström-Lunden, E.

    1999-01-01

    there is a shortage of measurement data to evaluate the deposition and reemission processes. It was concluded that the mechanisms of transport and dispersion of pesticides can be described similarly to those for other air pollution components and these mechanisms are rather well-known. Large uncertainties are present......The current knowledge on atmospheric transport and deposition of pesticides is reviewed and discussed by a working group of experts during the Workshop on Fate of pesticides in the atmosphere; implications for risk assessment, held in Driebergen, the Netherlands, 22-24 April, 1998. In general...

  5. Comparative ecophysiology of active zoobenthic filter feeding, essence of current knowledge

    Science.gov (United States)

    Riisgård, H. U.; Larsen, P. S.

    2000-12-01

    The present contribution gives an overview of current knowledge of a comprehensive and steadily growing research field. The first section deals with water pumping and particle retention mechanisms in ciliary and muscular filter feeders. The second section examines the biological filter pumps in order to assess adaptation to the environment. Filter-feeding benthic invertebrates have evolved filter pumps to solve common basic problems. This has led to a large degree of similarity between otherwise distant standing species, which makes comparative studies interesting and important. The present review of zoobenthic filter feeding aims at accentuating such recognition.

  6. Leber hereditary optic neuropathy - historical report in comparison with the current knowledge.

    Science.gov (United States)

    Piotrowska, Agnieszka; Korwin, Magdalena; Bartnik, Ewa; Tońska, Katarzyna

    2015-01-15

    Leber hereditary optic neuropathy (LHON) is a genetic, maternally inherited disease caused by point mutations in the mitochondrial genome. LHON patients present with sudden, painless and usually bilateral loss of vision caused by optic nerve atrophy. The first clinical description of the disease was made by Theodor Leber, a German ophthalmologist, in 1871. Here we present his thorough notes about members of four families and their pedigrees. We also provide insights into the current knowledge about LHON pathology, genetics and treatment in comparison with Leber's findings.

  7. Global forces and local currents in Argentina's science policy crossroads: restricted access or open knowledge

    Directory of Open Access Journals (Sweden)

    Horacio Javier Etchichury

    2014-11-01

    Full Text Available The article describes the tensions between two competing approaches to scientific policy in Argentina. The traditional vision favors autonomous research. The neoliberal conception fosters the link between science and markets. In the past few years, a neodevelopmentalist current also tries to stress relevance of scientific research. Finally, the article describes how the Open Access movement has entered the debate. The World Bank intervention and the human rights dimension of the question are discussed in depth. The article introduces the notion of open knowledge as a guiding criterion to design a human-rights based scientific policy.

  8. Investigation on public knowledge, attitude and practices related to ...

    African Journals Online (AJOL)

    Despite this there is limited information about public knowledge on pet husbandry ... proper pet management and zoonotic diseases prevention practices for pet-owning households, with concerted efforts by veterinary, human and public health ...

  9. Age-related macular degeneration: current treatment and future options.

    Science.gov (United States)

    Moutray, Tanya; Chakravarthy, Usha

    2011-09-01

    Age-related macular degeneration is the leading cause of visual impairment among older adults in the developed world. Epidemiological studies have revealed a number of genetic, ocular and environmental risk factors for this condition, which can be addressed by disease reduction strategies. We discuss the various treatment options for dry and exudative age-related macular degeneration available and explain how the recommended treatment depends on the exact type, location and extent of the degeneration. Currently, vascular endothelial growth factor (VEGF) inhibition therapy is the best available treatment for exudative age-related macular degeneration but is limited by the need for repeated intravitreal injections. The current treatment regime is being refined through research on optimal treatment frequency and duration and type of anti-VEGF drug. Different modes of drug delivery are being developed and in the future other methods of VEGF inhibition may be used.

  10. Preservice Teachers' Professional Knowledge and Its Relation to Academic Self-Concept

    Science.gov (United States)

    Paulick, Isabell; Großschedl, Jörg; Harms, Ute; Möller, Jens

    2016-01-01

    We investigated the factorial structure of preservice teachers' academic self-concept with regard to three domains of professional knowledge (content knowledge [CK], pedagogical content knowledge [PCK], and pedagogical/psychological knowledge [PPK]). We also analyzed the relation between preservice teachers' academic self-concept and their…

  11. Gender relations and health research: a review of current practices

    Directory of Open Access Journals (Sweden)

    Bottorff Joan L

    2011-12-01

    Full Text Available Abstract Introduction The importance of gender in understanding health practices and illness experiences is increasingly recognized, and key to this work is a better understanding of the application of gender relations. The influence of masculinities and femininities, and the interplay within and between them manifests within relations and interactions among couples, family members and peers to influence health behaviours and outcomes. Methods To explore how conceptualizations of gender relations have been integrated in health research a scoping review of the existing literature was conducted. The key terms gender relations, gender interactions, relations gender, partner communication, femininities and masculinities were used to search online databases. Results Through analysis of this literature we identified two main ways gender relations were integrated in health research: a as emergent findings; and b as a basis for research design. In the latter, gender relations are included in conceptual frameworks, guide data collection and are used to direct data analysis. Conclusions Current uses of gender relations are typically positioned within intimate heterosexual couples whereby single narratives (i.e., either men or women are used to explore the influence and/or impact of intimate partner gender relations on health and illness issues. Recommendations for advancing gender relations and health research are discussed. This research has the potential to reduce gender inequities in health.

  12. Adequacy of Physicians Knowledge Level of Cardiopulmonary Resuscitation to Current Guidelines

    Directory of Open Access Journals (Sweden)

    Ümmu Kocalar

    2016-01-01

    Full Text Available Aim: The purpose of this study is to test the level of information on CPR and suitability to current application of the phsicians practicing in hospital ANEAH. Material and Method: The form of a test of 20 questions fort his purpose has been prepared in accordance with the 2010 AHA-ERC CPR guidelines. This form distributed to volunteer physicians to fill in. A total of 173 physicians agreed to participate in he study. The results were analyzed statistically and tried to determine the factors affecting the level of information. Results:According to the results of the study physicians gender, age and the total duration of physicians and medical asistance doesn%u2019t affect the level of information. The number of CPR within 1 month positively affect the level of knowledge. The number of theoretical and practical training in medical school, have taken the positive impact the level of knowledge of physicians. The training period after graduation, significantly increased the level of physicians information. The order of these training sessions with the asistant courses, congress, seminars and lessions on the sempozims are effective. Discussion: CPR trainig programs for physicians should be standardized, updated and expanded. Recurent in-service trainig should be provided to increase phsicians knowledge on skills.

  13. The Immunology of Neuromyelitis Optica—Current Knowledge, Clinical Implications, Controversies and Future Perspectives

    Science.gov (United States)

    Jasiak-Zatonska, Michalina; Kalinowska-Lyszczarz, Alicja; Michalak, Slawomir; Kozubski, Wojciech

    2016-01-01

    Neuromyelitis optica (NMO) is an autoimmune, demyelinating disorder of the central nervous system (CNS) with typical clinical manifestations of optic neuritis and acute transverse myelitis attacks. Previously believed to be a variant of multiple sclerosis (MS), it is now considered an independent disorder which needs to be differentiated from MS. The discovery of autoantibodies against aquaporin-4 (AQP4-IgGs) changed our understanding of NMO immunopathogenesis and revolutionized the diagnostic process. AQP4-IgG is currently regarded as a specific biomarker of NMO and NMO spectrum disorders (NMOsd) and a key factor in its pathogenesis. Nevertheless, AQP4-IgG seronegativity in 10%–25% of NMO patients suggests that there are several other factors involved in NMO immunopathogenesis, i.e., autoantibodies against aquaporin-1 (AQP1-Abs) and antibodies against myelin oligodendrocyte glycoprotein (MOG-IgGs). This manuscript reviews current knowledge about NMO immunopathogenesis, pointing out the controversial issues and showing potential directions for future research. Further efforts should be made to broaden our knowledge of NMO immunology which could have important implications for clinical practice, including the use of potential novel biomarkers to facilitate an early and accurate diagnosis, and modern treatment strategies improving long-term outcome of NMO patients. PMID:26950113

  14. The Immunology of Neuromyelitis Optica-Current Knowledge, Clinical Implications, Controversies and Future Perspectives.

    Science.gov (United States)

    Jasiak-Zatonska, Michalina; Kalinowska-Lyszczarz, Alicja; Michalak, Slawomir; Kozubski, Wojciech

    2016-03-02

    Neuromyelitis optica (NMO) is an autoimmune, demyelinating disorder of the central nervous system (CNS) with typical clinical manifestations of optic neuritis and acute transverse myelitis attacks. Previously believed to be a variant of multiple sclerosis (MS), it is now considered an independent disorder which needs to be differentiated from MS. The discovery of autoantibodies against aquaporin-4 (AQP4-IgGs) changed our understanding of NMO immunopathogenesis and revolutionized the diagnostic process. AQP4-IgG is currently regarded as a specific biomarker of NMO and NMO spectrum disorders (NMOsd) and a key factor in its pathogenesis. Nevertheless, AQP4-IgG seronegativity in 10%-25% of NMO patients suggests that there are several other factors involved in NMO immunopathogenesis, i.e., autoantibodies against aquaporin-1 (AQP1-Abs) and antibodies against myelin oligodendrocyte glycoprotein (MOG-IgGs). This manuscript reviews current knowledge about NMO immunopathogenesis, pointing out the controversial issues and showing potential directions for future research. Further efforts should be made to broaden our knowledge of NMO immunology which could have important implications for clinical practice, including the use of potential novel biomarkers to facilitate an early and accurate diagnosis, and modern treatment strategies improving long-term outcome of NMO patients.

  15. The Immunology of Neuromyelitis Optica—Current Knowledge, Clinical Implications, Controversies and Future Perspectives

    Directory of Open Access Journals (Sweden)

    Michalina Jasiak-Zatonska

    2016-03-01

    Full Text Available Neuromyelitis optica (NMO is an autoimmune, demyelinating disorder of the central nervous system (CNS with typical clinical manifestations of optic neuritis and acute transverse myelitis attacks. Previously believed to be a variant of multiple sclerosis (MS, it is now considered an independent disorder which needs to be differentiated from MS. The discovery of autoantibodies against aquaporin-4 (AQP4-IgGs changed our understanding of NMO immunopathogenesis and revolutionized the diagnostic process. AQP4-IgG is currently regarded as a specific biomarker of NMO and NMO spectrum disorders (NMOsd and a key factor in its pathogenesis. Nevertheless, AQP4-IgG seronegativity in 10%–25% of NMO patients suggests that there are several other factors involved in NMO immunopathogenesis, i.e., autoantibodies against aquaporin-1 (AQP1-Abs and antibodies against myelin oligodendrocyte glycoprotein (MOG-IgGs. This manuscript reviews current knowledge about NMO immunopathogenesis, pointing out the controversial issues and showing potential directions for future research. Further efforts should be made to broaden our knowledge of NMO immunology which could have important implications for clinical practice, including the use of potential novel biomarkers to facilitate an early and accurate diagnosis, and modern treatment strategies improving long-term outcome of NMO patients.

  16. Stem cells for liver tissue repair:Current knowledge and perspectives

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Stem cells from extra- or intrahepatic sources have been recently characterized and their usefulness for the generation of hepatocyte-like lineages has been demonstrated.Therefore,they are being increasingly considered for future applications in liver cell therapy.In that field,liver cell transplantation is currently regarded as a possible alternative to whole organ transplantation,while stem cells possess theoretical advantages on hepatocytes as they display higher in vitro culture performances and could be used in autologous transplant procedures.However,the current research on the hepatic fate of stem cells is still facing difficulties to demonstrate the acquisition of a full mature hepatocyte phenotype,both in vitro and in vivo.Furthermore,the lack of obvious demonstration of in vivo hepatocyte-like cell functionality remains associated to low repopulation rates obtained after current transplantation procedures.The present review focuses on the current knowledge of the stern cell potential for liver therapy.We discuss the characteristics of the principal cell candidates and the methods to demonstrate their hepatic potential in vitro and in vivo.We finally address the question of the future clinical applications of stem cells for liver tissue repair and the technical aspects that remain to be investigated.

  17. 49 CFR 1544.235 - Training and knowledge for individuals with security-related duties.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Training and knowledge for individuals with... and knowledge for individuals with security-related duties. (a) No aircraft operator may use any... ensure that individuals performing security-related duties for the aircraft operator have knowledge...

  18. Knowledge in Action: Fitness Lesson Segments That Teach Health-Related Fitness in Elementary Physical Education

    Science.gov (United States)

    Hodges, Michael G.; Kulinna, Pamela Hodges; van der Mars, Hans; Lee, Chong

    2016-01-01

    The purpose of this study was to determine students' health-related fitness knowledge (HRFK) and physical activity levels after the implementation of a series of fitness lessons segments called Knowledge in Action (KIA). KIA aims to teach health-related fitness knowledge (HRFK) during short episodes of the physical education lesson. Teacher…

  19. Early detection of age related macular degeneration: current status

    OpenAIRE

    Schwartz, Roy; Loewenstein, Anat

    2015-01-01

    Early diagnosis and treatment of choroidal neovascularization (CNV), a main cause of severe vision loss in age related macular degeneration (AMD), is crucial in order to preserve vision and the quality of life of patients. This review summarizes current literature on the subject of early detection of CNV, both in the clinic setting and mainly in the patient’s home. New technologies are evolving to allow for earlier detection and thus vision preservation in AMD patients.

  20. Early detection of age related macular degeneration: current status.

    Science.gov (United States)

    Schwartz, Roy; Loewenstein, Anat

    2015-01-01

    Early diagnosis and treatment of choroidal neovascularization (CNV), a main cause of severe vision loss in age related macular degeneration (AMD), is crucial in order to preserve vision and the quality of life of patients. This review summarizes current literature on the subject of early detection of CNV, both in the clinic setting and mainly in the patient's home. New technologies are evolving to allow for earlier detection and thus vision preservation in AMD patients.

  1. Relating Knowledge about Reading to Teaching Practice: An Exploratory Validity Study of a Teacher Knowledge Assessment

    Science.gov (United States)

    Phelps, Geoffrey; Johnson, David; Carlisle, Joanne

    2009-01-01

    The research reported in this paper is focused directly on assessing the validity of the "Teaching Knowledge about Reading and Reading Practices" (TKRRP) assessment. Following the recommendations of the Standards for Educational and Psychological Testing (APA/AERA, 1999), the authors see validation as a process of constructing an…

  2. Children's Metacognition: Exploring Relations among Knowledge, Process, and Motivational Variables

    Science.gov (United States)

    Kurtz, Beth E.; Borkowski, John G.

    1984-01-01

    A total of 60 first- and third-grade children were divided into three treatment groups receiving task-specific strategy instructions and/or metacognitive training. Results were discussed in terms of the interactive nature of knowledge, process, and motivational variables as determinants of strategy transfer. (Author/CI)

  3. Survey of HIV/AIDS-related Knowledge, Attitude and Determinants in Urban Residents

    Institute of Scientific and Technical Information of China (English)

    何群; 杨放; 林鹏; 王晔; 刘勇鹰; 付笑冰; 赵茜茜

    2003-01-01

    Objectives: To provide references for HIV/AIDS-re-lated health education strategies through survey on HIV/AIDS-related knowledge, attitude and determi-nants of HIV/AIDS awareness.Methods: The study subjects were selected by ran-dom interception in a downtown street of Guangzhou city on World AIDS Day-December 1,2002. The uni-form questionnaires were finished by means of self-administration.Results: Two hundred questionnaires were distrib-uted and 147 qualified questionnaires were collected.The results showed, the awareness rate of HIV/AIDS-related knowledge was 63.3%, and awareness rate of transmission routes was 76.2 %, whilst non-transmis-sion route was 60.5 %; the awareness rate of trans-mission was 59.2%; the awareness rate of prevention was 47.0%; the positive attitude to people living with HIV/AIDS was 65.6%. Multiple variable Logistic re-gression analysis showed the determinants of HIV/AIDS-related knowledge were education level, age,marital status and gender, of which people with high level of education, young age and the group of male and married had better awareness of HIV/AIDS.Conclusion: Current HIV/AIDS-related knowledge of urban residents is relativly low, especially for the non-transmission route, hence further HIV/AIDS-re-lated education should be strengthened, especially fo-cusing on non-transmission route to eliminate dis-crimination over people living with HIV/AIDS.Further, education efforts also should be put on fe-male population, unmarried population and poorly edu-cated population.

  4. Survival in extreme environments - on the current knowledge of adaptations in tardigrades.

    Science.gov (United States)

    Møbjerg, N; Halberg, K A; Jørgensen, A; Persson, D; Bjørn, M; Ramløv, H; Kristensen, R M

    2011-07-01

    Tardigrades are microscopic animals found worldwide in aquatic as well as terrestrial ecosystems. They belong to the invertebrate superclade Ecdysozoa, as do the two major invertebrate model organisms: Caenorhabditis elegans and Drosophila melanogaster. We present a brief description of the tardigrades and highlight species that are currently used as models for physiological and molecular investigations. Tardigrades are uniquely adapted to a range of environmental extremes. Cryptobiosis, currently referred to as a reversible ametabolic state induced by e.g. desiccation, is common especially among limno-terrestrial species. It has been shown that the entry and exit of cryptobiosis may involve synthesis of bioprotectants in the form of selective carbohydrates and proteins as well as high levels of antioxidant enzymes and other free radical scavengers. However, at present a general scheme of mechanisms explaining this phenomenon is lacking. Importantly, recent research has shown that tardigrades even in their active states may be extremely tolerant to environmental stress, handling extreme levels of ionizing radiation, large fluctuation in external salinity and avoiding freezing by supercooling to below -20 °C, presumably relying on efficient DNA repair mechanisms and osmoregulation. This review summarizes the current knowledge on adaptations found among tardigrades, and presents new data on tardigrade cell numbers and osmoregulation.

  5. ['I'm worthless' and other forms of self-criticism: Current knowledge and therapeutic interventions].

    Science.gov (United States)

    Maillard, Pauline; Kramer, Ueli

    2015-01-01

    Self-criticism is considered as a harsh or punitive evaluation of the self. It is omnipresent in culture, in daily life as well as in psychotherapy. Self-criticism can lead to question oneself but can also open new perspectives and guide us. However, it can become excessive, rigid, and might turn out to be deleterious. This present article focuses on the concept of self-criticism in clinical psychology and psychotherapy and aims to review current knowledge about this topic. First, its definition and the reasons for its development in individuals will be presented. Second, a description of the links between self-criticism and psychopathology will be made, in particular regarding depression. Finally, the third part of this article will be dedicated to the therapeutic interventions that can reduce self-criticism.

  6. Chemical and molecular factors in irritable bowel syndrome: current knowledge, challenges, and unanswered questions.

    Science.gov (United States)

    Camilleri, Michael; Oduyebo, Ibironke; Halawi, Houssam

    2016-11-01

    Several chemical and molecular factors in the intestine are reported to be altered and to have a potentially significant role in irritable bowel syndrome (IBS), particularly in IBS with diarrhea. These include bile acids; short-chain fatty acids; mucosal barrier proteins; mast cell products such as histamine, proteases, and tryptase; enteroendocrine cell products; and mucosal mRNAs, proteins, and microRNAs. This article reviews the current knowledge and unanswered questions in the pathobiology of the chemical and molecular factors in IBS. Evidence continues to point to significant roles in pathogenesis of these chemical and molecular mechanisms, which may therefore constitute potential targets for future research and therapy. However, it is still necessary to address the interaction between these factors in the gut and to appraise how they may influence hypervigilance in the central nervous system in patients with IBS. Copyright © 2016 the American Physiological Society.

  7. Physiological Reactivity to Psychological Stress in Human Pregnancy: Current Knowledge and Future Directions

    Science.gov (United States)

    Christian, Lisa M.

    2012-01-01

    Cardiovascular and neuroendocrine reactivity to acute stress are important predictors of health outcomes in non-pregnant populations. Greater magnitude and duration of physiological responses have been associated with increased risk of hypertensive disorders and diabetes, greater susceptibility to infectious illnesses, suppression of cell-mediated immunity as well as risk for depression and anxiety disorders. Stress reactivity during pregnancy has unique implications for maternal health, birth outcomes, and fetal development. However, as compared to the larger literature, our understanding of the predictors and consequences of exaggerated stress reactivity in pregnancy is limited. This paper reviews the current state of this literature with an emphasis on gaps in knowledge and future directions. PMID:22800930

  8. Knowledge, Beliefs and Behaviours Related to STD Risk, Prevention, and Screening among a Sample of African American Men and Women

    Science.gov (United States)

    Uhrig, Jennifer D.; Friedman, Allison; Poehlman, Jon; Scales, Monica; Forsythe, Ann

    2014-01-01

    Objective: Current data on sexually transmitted disease (STD) among African Americans show significant racial/ethnic disparities. The purpose of this study was to explore knowledge, attitudes, beliefs, and behaviours related to STD risk, prevention, and testing among African American adults to help inform the development of a health communication…

  9. Sexual and reproductive health status and related knowledge among female migrant workers in Guangzhou, China: a cross-sectional survey

    NARCIS (Netherlands)

    Lu, C.; Xu, L.; Wu, J.; Wang, Z.; Decat, P.; Zhang, W.-H.; Cheng, Y.; Moyer, E.; Wu, S.; Minkauskiene, M.; van Braeckel, D.; Temmerman, M.

    2012-01-01

    The objective of this study was to investigate the current sexual and reproductive health (SRH) status including SRH-related knowledge and associated factors, self-reported symptoms of reproductive tract infection (RTI), medical assistance seeking behavior, sexual experience and contraceptive use, r

  10. Sexual and reproductive health status and related knowledge among female migrant workers in Guangzhou, China: a cross-sectional survey

    NARCIS (Netherlands)

    Lu, C.; Xu, L.; Wu, J.; Wang, Z.; Decat, P.; Zhang, W.-H.; Cheng, Y.; Moyer, E.; Wu, S.; Minkauskiene, M.; van Braeckel, D.; Temmerman, M.

    2012-01-01

    The objective of this study was to investigate the current sexual and reproductive health (SRH) status including SRH-related knowledge and associated factors, self-reported symptoms of reproductive tract infection (RTI), medical assistance seeking behavior, sexual experience and contraceptive use,

  11. Current knowledge on the photoneuroendocrine regulation of reproduction in temperate fish species.

    Science.gov (United States)

    Migaud, H; Davie, A; Taylor, J F

    2010-01-01

    Seasonality is an important adaptive trait in temperate fish species as it entrains or regulates most physiological events such as reproductive cycle, growth profile, locomotor activity and key life-stage transitions. Photoperiod is undoubtedly one of the most predictable environmental signals that can be used by most living organisms including fishes in temperate areas. This said, however, understanding of how such a simple signal can dictate the time of gonadal recruitment and spawning, for example, is a complex task. Over the past few decades, many scientists attempted to unravel the roots of photoperiodic signalling in teleosts by investigating the role of melatonin in reproduction, but without great success. In fact, the hormone melatonin is recognized as the biological time-keeping hormone in fishes mainly due to the fact that it reflects the seasonal variation in daylength across the whole animal kingdom rather than the existence of direct evidences of its role in the entrainment of reproduction in fishes. Recently, however, some new studies clearly suggested that melatonin interacts with the reproductive cascade at a number of key steps such as through the dopaminergic system in the brain or the synchronization of the final oocyte maturation in the gonad. Interestingly, in the past few years, additional pathways have become apparent in the search for a fish photoneuroendocrine system including the clock-gene network and kisspeptin signalling and although research on these topics are still in their infancy, it is moving at great pace. This review thus aims to bring together the current knowledge on the photic control of reproduction mainly focusing on seasonal temperate fish species and shape the current working hypotheses supported by recent findings obtained in teleosts or based on knowledge gathered in mammalian and avian species. Four of the main potential regulatory systems (light perception, melatonin, clock genes and kisspeptin) in fish reproduction

  12. What Is the Current Level of Asthma Knowledge in Elementary, Middle, and High School Teachers?

    Science.gov (United States)

    Carey, Stephen

    2013-01-01

    This study examined teacher asthma knowledge based on three areas including (a) the level of teacher asthma knowledge in the Maury County Public School System, (b) the level of teacher asthma knowledge based on five demographic factors, and (c) the level of teacher asthma knowledge in the Maury County Public School System compared with teacher…

  13. The Baltic policy of Germany and current international relations

    Directory of Open Access Journals (Sweden)

    Salikov Aleksey

    2016-03-01

    Full Text Available This article analyses the Baltic policy of united Germany from the 1990s until today. The authors set out to identify the significance of German-Baltic relations and the role of the Eastern policy in Russian-German relations. The method of dynamic comparison between the political and economic narrative in intergovernmental relations makes it possible to identify distinctive features of Germany’s Baltic policy in the context of current international relations. In particular, it is noted that Germany was most active in the Baltic region in the 1990s, when the country was establishing political, economic, and cultural ties with the new independent states. In the second half of the 1990s, Germany’s foreign policy became less intense. After the accession of Lithuania, Latvia, and Estonia to the EU and NATO in 2004, certain disagreements started to arise between Germany and the Baltics. It explains the lukewarm relations between them. The Ukraine events brought about a change in Germany’s regional policy. Despite Russia remaining one of the key economic and political counteractors, Germany, being a partner of the Baltics in the EU and NATO, cannot adopt a neutral position in the conflict of interests between the Baltics and Russia.

  14. Capacitively coupled nano conductors. Ratchet currents and exchange fluctuation relations

    Energy Technology Data Exchange (ETDEWEB)

    Hussein, Robert; Kohler, Sigmund [Instituto de Ciencia de Materiales de Madrid, CSIC, 28049 Madrid (Spain)

    2015-10-15

    We investigate electron transport in two quantum circuits with mutual Coulomb interaction. The first circuit is a double quantum dot connected to two electron reservoirs, while the second one is a quantum point contact in the weak tunneling limit. The coupling is such that an electron in the first circuit enhances the barrier of the point contact and, thus, reduces its conductivity. While such setups are frequently used as charge monitors, we focus on two different aspects. First, we derive transport coefficients which have recently been employed for testing generalized equilibrium conditions known as exchange fluctuation relations. These formally exact relations allow us to test the consistency of our master equation approach. Second, a biased point contact entails noise on the DQD and induces non-equilibrium phenomena such as a ratchet current. (copyright 2015 by WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  15. Student Teachers' Knowledge about Children with ADHD and Depression and Its Relations to Emotions

    Science.gov (United States)

    Kikas, Eve; Timoštšuk, Inge

    2016-01-01

    Student teachers' knowledge about children with attention deficit hyperactivity disorder (ADHD) and depression and its relations to reporting experiencing emotions during teaching practice were studied. The participants were 186 teacher education students in Estonia. Student teachers' general knowledge and confidence in knowledge varied a lot.…

  16. The order Corallinales sensu lato (Rhodophyta in the Iberian Atlantic: current state of knowledge

    Directory of Open Access Journals (Sweden)

    Juan Lugilde

    2016-09-01

    Full Text Available A review of the order Corallinales sensu lato in the Atlantic Iberian Peninsula is presented with the aim of assessing its current state of knowledge in comparison with adjacent areas (British Isles-Atlantic France, Macaronesia and Iberian Mediterranean. According to the information compiled from more than 250 publications, herbarium data and manuscripts, we concluded that Atlantic Iberian coralline algae have been poorly studied, which resulted in only 49 species reported. By contrast, Macaronesia is the most species-rich region (91, followed by Spanish Mediterranean (67 and the British Isles-Atlantic France (61. In the Atlantic Iberian Peninsula, 17 species occurred commonly (present in more than 50% of the coastline, particularly those corresponding to the genera Amphiroa, Jania, Lithophyllum, Mesophyllum, and Phymatolithon. Instead, the genera Harveylithon, Hydrolithon, Leptophytum, Lithothamnion, Neogoniolithon and Pneophyllum have been occasionally reported. In the Atlantic Iberian Peninsula and adjacent regions, the epilithic growth-form was dominant, followed by the epiphytic, epizoic and the unattached (maerl/rodoliths; besides, sciaphilous taxa were more abundant than photophilous species. The low intertidal and shallow subtidal harbour a high diversity of coralline algae, as well as semi-exposed coasts or areas affected by currents. The present study confirms that studies on the Atlantic Iberian coralline algae are scarce, and that further research on this group is required.

  17. B-group vitamin production by lactic acid bacteria--current knowledge and potential applications.

    Science.gov (United States)

    LeBlanc, J G; Laiño, J E; del Valle, M Juarez; Vannini, V; van Sinderen, D; Taranto, M P; de Valdez, G Font; de Giori, G Savoy; Sesma, F

    2011-12-01

    Although most vitamins are present in a variety of foods, human vitamin deficiencies still occur in many countries, mainly because of malnutrition not only as a result of insufficient food intake but also because of unbalanced diets. Even though most lactic acid bacteria (LAB) are auxotrophic for several vitamins, it is now known that certain strains have the capability to synthesize water-soluble vitamins such as those included in the B-group (folates, riboflavin and vitamin B(12) amongst others). This review article will show the current knowledge of vitamin biosynthesis by LAB and show how the proper selection of starter cultures and probiotic strains could be useful in preventing clinical and subclinical vitamin deficiencies. Here, several examples will be presented where vitamin-producing LAB led to the elaboration of novel fermented foods with increased and bioavailable vitamins. In addition, the use of genetic engineering strategies to increase vitamin production or to create novel vitamin-producing strains will also be discussed. This review will show that the use of vitamin-producing LAB could be a cost-effective alternative to current vitamin fortification programmes and be useful in the elaboration of novel vitamin-enriched products. © 2011 The Authors. Journal of Applied Microbiology © 2011 The Society for Applied Microbiology.

  18. How Do Clinicians Learn About Knowledge Translation? An Investigation of Current Web-Based Learning Opportunities.

    Science.gov (United States)

    Damarell, Raechel A; Tieman, Jennifer J

    2017-07-13

    Clinicians are important stakeholders in the translation of well-designed research evidence into clinical practice for optimal patient care. However, the application of knowledge translation (KT) theories and processes may present conceptual and practical challenges for clinicians. Online learning platforms are an effective means of delivering KT education, providing an interactive, time-efficient, and affordable alternative to face-to-face education programs. This study investigates the availability and accessibility of online KT learning opportunities for health professionals. It also provides an analysis of the types of resources and associated disciplines retrieved by a range of KT synonyms. We searched a range of bibliographic databases and the Internet (Google advanced option) using 9 KT terms to identify online KT learning resources. To be eligible, resources had to be free, aimed at clinicians, educational in intent, and interactive in design. Each term was searched using two different search engines. The details of the first 100 websites captured per browser (ie, n=200 results per term) were entered into EndNote. Each site was subsequently visited to determine its status as a learning resource. Eligible websites were appraised for quality using the AACODS (Authority, Accuracy, Coverage, Objectivity, Date, Significance) tool. We identified 971 unique websites via our multiple search strategies. Of these, 43 were health-related and educational in intent. Once these sites were evaluated for interactivity, a single website matched our inclusion criteria (Dementia Knowledge Translation Learning Centre). KT is an important but complex system of processes. These processes overlap with knowledge, practice, and improvement processes that go by a range of different names. For clinicians to be informed and competent in KT, they require better access to free learning opportunities. These resources should be designed from the viewpoint of the clinician, presenting KT

  19. Background Knowledge in Learning-Based Relation Extraction

    Science.gov (United States)

    2012-01-01

    chapter in Section 3.7. 17 Examples Label Relation Term x Term y x← y x is an ancestor of y actor Mel Gibson food rice wine Champagne x→ y x is a descendant...a sibling relation to infer that a statement about Taiwan 14 (without additional information) is not likely to entail a hypothesis about Japan since...struck Japan . Naturally, these taxonomic relations can be read off from manually generated resources such as Wordnet that explicitly represent these

  20. Comparison of knowledge of and attitudes toward dementia between health-related and non-health-related university students

    OpenAIRE

    Yong, Mi-hyun; Yoo, Chan-uk; Yang, Yeong-ae

    2015-01-01

    [Purpose] This study compared the knowledge of and attitudes toward dementia between health-related and non-health-related students. [Subjects] The subjects consisted of a total of 416 people, 213 health-related students and 203 non-health-related students, at K University, which is located in Gyeongsangbuk-do, Republic of Korea, between May 1 and 14, 2014. [Methods] The subjects answered a self-administered questionnaire about their knowledge of and attitudes toward dementia. [Results] There...

  1. Reviewing current knowledge in snatch performance and technique: the need for future directions in applied research.

    Science.gov (United States)

    Ho, Lester K W; Lorenzen, Christian; Wilson, Cameron J; Saunders, John E; Williams, Morgan D

    2014-02-01

    This is a review of current research trends in weightlifting literature relating to the understanding of technique and its role in successful snatch performance. Reference to the world records in the snatch from the 1960s onwards indicates little progress across all weight categories. With such mediocre advances in performance at the International level, there is a need to better understand how snatch technique can improve performance even if only by a small margin. Methods of data acquisition for technical analysis of the snatch have involved mostly 2-dimensional barbell and joint kinematics. Although key variables which play a role in the successful outcome of a snatch lift have been heavily investigated, few studies have combined variables relating both the barbell and the weightlifter in their analyses. This suggests the need for a more detailed approach integrating both barbell-related and weightlifter-related data to enhance understanding of the mechanics of a successful lift. Currently, with the aid of technical advances in motion analysis, data acquisition, and methods of analysis, a more accurate representation of the movement can be provided. Better ways of understanding the key characteristics of technique in the snatch could provide the opportunity for more effective individualized feedback from the coach to the athlete, which should in turn lead to improved performance in competition.

  2. General practitioners knowledge, practice and training requirements in relation to doping in sport.

    Science.gov (United States)

    Woods, C B; Moynihan, A

    2009-01-01

    This study examined General Practitioner's (GP) knowledge, practice and training requirements in relation to doping in sport in Ireland. All 2083 GPs on the Irish College of General Practitioners (ICGP) register received a postal questionnaire, yielding a 37% response rate (N=771, 63% male, average age 46.2 +/- 9SD, range 28-74 years). Results revealed that 14% (112) deemed their knowledge of doping agents to be good or very good, 12% (94) had completed specific training modules in doping or sport, and 24% (183) were connected with a specific sport as a team doctor/advisor. Over one in four (28%: 217) had been consulted for advice on doping in Sport, 33% (256) possessed the current list of prohibited substances, and 25% (190) knew of the Irish Sports Council's drug-testing procedures. The current initiatives to discourage doping in sport were felt to be ineffective, and although 92% (716) indicated that GPs had a role to play in the prevention of doping in sport, only 9% (66) felt adequately trained for such a role. There was overwhelming support for further training among GPs, although the most appropriate method of providing training is complex and requires strategic planning.

  3. Relation between magnetic fields and electric currents in plasmas

    Directory of Open Access Journals (Sweden)

    V. M. Vasyliunas

    2005-10-01

    Full Text Available Maxwell's equations allow the magnetic field B to be calculated if the electric current density J is assumed to be completely known as a function of space and time. The charged particles that constitute the current, however, are subject to Newton's laws as well, and J can be changed by forces acting on charged particles. Particularly in plasmas, where the concentration of charged particles is high, the effect of the electromagnetic field calculated from a given J on J itself cannot be ignored. Whereas in ordinary laboratory physics one is accustomed to take J as primary and B as derived from J, it is often asserted that in plasmas B should be viewed as primary and J as derived from B simply as (c/4π∇×B. Here I investigate the relation between ∇×B and J in the same terms and by the same method as previously applied to the MHD relation between the electric field and the plasma bulk flow vmv2001: assume that one but not the other is present initially, and calculate what happens. The result is that, for configurations with spatial scales much larger than the electron inertial length λe, a given ∇×B produces the corresponding J, while a given J does not produce any ∇×B but disappears instead. The reason for this can be understood by noting that ∇×B≠4π/cJ implies a time-varying electric field (displacement current which acts to change both terms (in order to bring them toward equality; the changes in the two terms, however, proceed on different time scales, light travel time for B and electron plasma period for J, and clearly the term changing much more slowly is the one that survives. (By definition, the two time scales are equal at λe. On larger scales, the evolution of B (and hence also of ∇×B is governed by

  4. Global Assessment of Functioning (GAF: properties and frontier of current knowledge

    Directory of Open Access Journals (Sweden)

    Aas IH Monrad

    2010-05-01

    Full Text Available Abstract Background Global Assessment of Functioning (GAF is well known internationally and widely used for scoring the severity of illness in psychiatry. Problems with GAF show a need for its further development (for example validity and reliability problems. The aim of the present study was to identify gaps in current knowledge about properties of GAF that are of interest for further development. Properties of GAF are defined as characteristic traits or attributes that serve to define GAF (or may have a role to define a future updated GAF. Methods A thorough literature search was conducted. Results A number of gaps in knowledge about the properties of GAF were identified: for example, the current GAF has a continuous scale, but is a continuous or categorical scale better? Scoring is not performed by setting a mark directly on a visual scale, but could this improve scoring? Would new anchor points, including key words and examples, improve GAF (anchor points for symptoms, functioning, positive mental health, prognosis, improvement of generic properties, exclusion criteria for scoring in 10-point intervals, and anchor points at the endpoints of the scale? Is a change in the number of anchor points and their distribution over the total scale important? Could better instructions for scoring within 10-point intervals improve scoring? Internationally, both single and dual scales for GAF are used, but what is the advantage of having separate symptom and functioning scales? Symptom (GAF-S and functioning (GAF-F scales should score different dimensions and still be correlated, but what is the best combination of definitions for GAF-S and GAF-F? For GAF with more than two scales there is limited empirical testing, but what is gained or lost by using more than two scales? Conclusions In the history of GAF, its basic properties have undergone limited changes. Problems with GAF may, in part, be due to lack of a research programme testing the effects of

  5. Knowledge, opinions and practices of healthcare workers related to infant feeding in the context of HIV

    Directory of Open Access Journals (Sweden)

    Liska Janse van Rensburg

    2016-12-01

    Conclusion: Healthcare workers' knowledge did not conform favourably with the current WHO guidelines. These healthcare workers were actively involved in the care of patients in the maternity wards where HIV-infected mothers regularly seek counselling on infant feeding matters.

  6. Organizational options for preventing work-related stress in knowledge work

    DEFF Research Database (Denmark)

    Ipsen, Christine; Jensen, Per Langaa

    2012-01-01

    Recent studies point to work-related stress as an increasing problem for knowledge workers. However, the working life in knowledge-intensive companies is often described as good and stimulating. The aim of this study is to explore the organizational options for preventing work-related problems...... in knowledge work. This calls for a study of the characteristics of knowledge work, stress management interventions and an in-depth analysis of the organizational factors causing frustrations and work-related problems in relation to knowledge work. In a qualitative study, 27 respondents were interviewed...... productivity. Relevance to industry: The paper identifies organizational options on which managers, employees and ergonomists can focus when initiating new stress management practices and preventive changes aimed at redesigning knowledge work. (C) 2012 Elsevier B.V. All rights reserved....

  7. Minimally Invasive Transforaminal Lumbar Interbody Fusion: A Perspective on Current Evidence and Clinical Knowledge

    Directory of Open Access Journals (Sweden)

    Ali Habib

    2012-01-01

    Full Text Available This paper reviews the current published data regarding open transforaminal lumbar interbody fusion (TLIF in relation to minimally invasive transforaminal lumbar interbody fusion (MI-TLIF. Introduction. MI-TLIF, a modern method for lumbar interbody arthrodesis, has allowed for a minimally invasive method to treat degenerative spinal pathologies. Currently, there is limited literature that compares TLIF directly to MI-TLIF. Thus, we seek to discuss the current literature on these techniques. Methods. Using a PubMed search, we reviewed recent publications of open and MI-TLIF, dating from 2002 to 2012. We discussed these studies and their findings in this paper, focusing on patient-reported outcomes as well as complications. Results. Data found in 14 articles of the literature was analyzed. Using these reports, we found mean follow-up was 20 months. The mean patient study size was 52. Seven of the articles directly compared outcomes of open TLIF with MI-TLIF, such as mean duration of surgery, length of post-operative stay, blood loss, and complications. Conclusion. Although high-class data comparing these two techniques is lacking, the current evidence supports MI-TLIF with outcomes comparable to that of the traditional, open technique. Further prospective, randomized studies will help to further our understanding of this minimally invasive technique.

  8. [Breastfeeding in relation to knowledge and social support].

    Science.gov (United States)

    Kvist, B; Katajavuori, G; Viemero, V

    1988-01-01

    It has been suggested that every country undergoes 3 stages of development in its attitude toward breast feeding. The 1st or traditional stage is characterized by mothers breast feeding their children for a long time. The 2nd stage is a strong downswing in the popularity of breast feeding. The 3rd stage is a period during which breast feeding undergoes a renaissance. By 1979 about half of the mothers in Finland nursed their children for at least 6 months. In a study of 100 primiparae the 17-36 year olds (mean 24.7/) completed 4 questionnaires in the period from delivery up to the termination of breast feeding. In no case did this period exceed 5 months, at which time 60% of the women were still lactating. Age correlated significantly with the desire to nurse longer as did support received from the child's father, although support from health services sources was more significant. Mothers with higher work status had significantly more knowledge of breast feeding before nursing began and nursed significantly longer than women with lower work status. Women who nursed at least 5 months had significantly better expulsion reflex during delivery, did not need additives to mother's milk, and had a more positive experience with nursing after 3 weeks than women who nursed for a shorter time. Women who nursed for a longer period also had significant difference in the experience of nursing as an expression of contact and as an expression of sexuality.

  9. Process based inventory of isoprenoid emissions from European forests: model comparisons, current knowledge and uncertainties

    Directory of Open Access Journals (Sweden)

    T. Keenan

    2009-03-01

    Full Text Available Large uncertainties exist in our knowledge of regional emissions of non-methane biogenic volatile organic compounds (BVOC. We address these uncertainties through a two-pronged approach by compiling a state of the art database of the emissions potentials for 80 European forest species, and by a model assessment and inter-comparison, both at the local and regional scale, under present and projected future climatic conditions. We coupled three contrasting isoprenoid models with the ecophysiological forest model GOTILWA+ to explore the interactive effects of climate, vegetation distribution, and productivity, on leaf and ecosystem isoprenoid emissions, and to consider model behaviour in present climate and under projected future climate change conditions. Hourly, daily and annual isoprene emissions as simulated by the models were evaluated against flux measurements. The validation highlighted a general model capacity to capture gross fluxes but inefficiencies in capturing short term variability. A regional inventory of isoprenoid emissions for European forests was created using each of the three modelling approaches. The models agreed on an average European emissions budget of 1.03 TgC a−1 for isoprene and 0.97 TgC a−1 for monoterpenes for the period 1960–1990, which was dominated by a few species with largest aerial coverage. Species contribution to total emissions depended both on species emission potential and geographical distribution. For projected future climate conditions, however, emissions budgets proved highly model dependent, illustrating the current uncertainty associated with isoprenoid emissions responses to potential future conditions. These results suggest that current model estimates of isoprenoid emissions concur well, but future estimates are highly uncertain. We conclude that development of reliable models is highly urgent, but for the time being, future BVOC emission scenario estimates should consider

  10. Local Knowledge(s): Notes on Race Relations, Panethnicity and History in Hawai'i.

    Science.gov (United States)

    Chang, Jeff

    1996-01-01

    Examines the emergence and fragmentation of the panethnic Local in Hawaiian interracial relations. It explores, within the fractious debate over affirmative action in the 1970s and 1980s, the underrepresented island minorities' challenging of the privileged Local elite that intensified inter-Asian-Pacific tensions and fragmented the panethnic…

  11. Constructing Domain-Specific Knowledge in Kindergarten: Relations among Knowledge, Intelligence, and Strategic Performance

    Science.gov (United States)

    Alexander, Joyce M.; Johnson, Kathy E.; Leibham, Mary E.; DeBauge, Christiane

    2005-01-01

    Thirty kindergarten children from two classrooms participated in a 3-week curricular unit on dinosaurs designed to teach taxonomic relations and distinguishing features aligned with 15 dinosaur species. Both domain-specific learning and strategic performance on a Twenty Questions game were assessed twice throughout the curriculum, as well as…

  12. Related General-Vocabulary Knowledge Transfers to Learning Technical Terms

    Science.gov (United States)

    Balch, William R.

    2015-01-01

    In a classroom experiment during the first week of an introductory psychology course, randomly assigned students received a pretest and then a brief training on the definitions of general-vocabulary words either related (e.g., "facilitation") or unrelated (e.g., "rendition") to 16 technical terms (e.g., "social…

  13. Patient knowledge, perceptions, and acceptance of generic medicines: a comprehensive review of the current literature

    Directory of Open Access Journals (Sweden)

    Alrasheedy AA

    2014-04-01

    Full Text Available Alian A Alrasheedy,1 Mohamed Azmi Hassali,1 Kay Stewart,2 David CM Kong,2 Hisham Aljadhey,3 Mohamed Izham Mohamed Ibrahim,4 Saleh Karamah Al-Tamimi1 1Discipline of Social and Administrative Pharmacy, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, Malaysia; 2Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Melbourne, VIC, Australia; 3Medication Safety Research Chair, Clinical Pharmacy Department, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia; 4College of Pharmacy, Qatar University, Doha, Qatar Background: Generic medicines have the same quality, safety, and efficacy as their counterpart original brand medicines. Generic medicines provide the same therapeutic outcomes but at a much cheaper cost, so are promoted in many countries to contain pharmaceutical expenditure and sustain the health care system. Thus, the perspective of patients and medicine consumers as end users of these medicines is an important factor to enhance the use and utilization of generic medicines. The objective of this paper is to review patients’ and consumers’ knowledge, perceptions, acceptance, and views of generic medicines in the current literature. Methods: An extensive literature search was performed in several databases, namely Scopus, PubMed, ISI Web of Knowledge, Proquest, and the Wiley online library, to identify relevant studies published in the English literature for the period 1990–2013. Results: A total of 53 studies were included in the review, comprising 24 studies from Europe, ten from North America, six from Asia, five from Australia and New Zealand, five from the Middle East, one from Africa, one from Latin America, and one from the Caribbean region. A large body of literature has reported misconceptions and negative perceptions about generic medicines on the part of patients and medicine consumers. Moreover, although it is reported in almost all countries, the percentage of consumers who had

  14. The iron-sulfur cluster assembly machineries in plants: current knowledge and open questions

    Directory of Open Access Journals (Sweden)

    Jérémy eCouturier

    2013-07-01

    Full Text Available Many metabolic pathways and cellular processes occurring in most sub-cellular compartments depend on the functioning of iron-sulfur (Fe-S proteins, whose cofactors are assembled through dedicated protein machineries. Recent advances have been made in the knowledge of the functions of individual components through a combination of genetic, biochemical and structural approaches, primarily in prokaryotes and non-plant eukaryotes. Whereas most of the components of these machineries are conserved between kingdoms, their complexity is likely increased in plants owing to the presence of additional assembly proteins and to the existence of expanded families for several assembly proteins. This review focuses on the new actors discovered in the past few years, such as glutaredoxin, BOLA and NEET proteins as well as MIP18, MMS19, TAH18, DRE2 for the cytosolic machinery, which are integrated into a model for the plant Fe-S cluster biogenesis systems. It also discusses a few issues currently subjected to an intense debate such as the role of the mitochondrial frataxin and of glutaredoxins, the functional separation between scaffold, carrier and iron-delivery proteins and the crosstalk existing between different organelles.

  15. Epidemiology of leishmaniasis in Ecuador: current status of knowledge -- a review.

    Science.gov (United States)

    Calvopina, Manuel; Armijos, Rodrigo X; Hashiguchi, Yoshihisa

    2004-11-01

    Although leishmaniasis is regarded as a significant health problem in Ecuador by the Ministry of Health, and the incidence has increased over the last years, an official map on the geographic distribution of disease and sand fly vectors or a control strategy do not exist yet. This article reviews the current situation based on published information to improve our knowledge and understand the epidemiological situation of leishmaniasis in Ecuador in order to help future research and to develop a national control strategy. The disease is endemic in most provinces throughout Pacific coastal region, Amazonian lowlands, and some inter-Andean valleys with a total 21,805 cases reported during 1990-2003. Whereas cutaneous leishmaniasis (CL) is found throughout Ecuador, mucocutaneous leishmaniasis (MCL) appears to be restricted to the Amazon region; one, parasitologically unconfirmed case of visceral form was reported in 1949. Most human infections are caused by Leishmania (Viannia) spp., which is distributed in the subtropical and tropical lowlands; infections due to L. (Leishmania) spp. are found in the Andean highlands and in the Pacific lowlands as well. The proven vectors are Lutzomyia trapidoi and Lu. ayacuchensis. Canis familiaris, Sciurus vulgaris, Potos flavus, and Tamandua tetradactyla have been found infected with Leishmania spp. It is estimated that around 3000-4500 people may be infected every year, and that 3.1 to 4.5 millions people are estimated to be at risk of contracting leishmaniasis.

  16. The trigemino-cardiac reflex: an update of the current knowledge.

    Science.gov (United States)

    Schaller, Bernhard; Cornelius, Jan F; Prabhakar, Hemanshu; Koerbel, Andrei; Gnanalingham, Kanna; Sandu, Nora; Ottaviani, Giulia; Filis, Andreas; Buchfelder, Michael

    2009-07-01

    The trigemino-cardiac reflex (TCR) is clinically defined as the sudden onset of parasympathetic activity, sympathetic hypotension, apnea, or gastric hypermotility during central or peripheral stimulation of any of the sensory branches of the trigeminal nerve. Clinically, the TCR has been reported to occur during craniofacial surgery, manipulation of the trigeminal nerve/ganglion and during surgery for lesion in the cerebellopontine angle, cavernous sinus, and the pituitary fossa. Apart from the few clinical reports, the physiologic function of this brainstem reflex has not yet been fully explored. The manifestation of the TCR can vary from bradycardia and hypotension to asystole. From the experimental findings, the TCR represents an expression of a central reflex leading to rapid cerebrovascular vasodilatation generated from excitation of oxygen-sensitive neurons in the rostral ventro-lateral medulla oblongata. By this physiologic response, the systemic and cerebral circulations may be adjusted in a way that augments cerebral perfusion. This review summarizes the current state of knowledge about TCR.

  17. A REVIEW OF CURRENT KNOWLEDGE CONCERNING SIZE-DEPENDENT AEROSOL REMOVAL

    Institute of Scientific and Technical Information of China (English)

    Leiming Zhang; Robert Vet

    2006-01-01

    The status of current knowledge on size-dependent aerosol removal by dry and wet processes, including dry deposition and impaction and nucleation scavenging, is reviewed. The largest discrepancies between theoretical estimations and measurement data on dry deposition and below-cloud scavenging are for submicron particles. Early dry deposition models, which developed based on chamber and wind tunnel measurements, tended to underestimate dry deposition velocity (Vd) for submicron particles by around one order of magnitude compared to recent field measurements. Recently developed models are able to predict reasonable Vd values for submicron particles but shift unrealistically the predicted minimum Vd to larger particle sizes. Theoretical studies of impaction scavenging of aerosol particles by falling liquid drops also substantially underestimate the scavenging coefficients for submicron particles. Empirical formulas based on field measurements can serve as an alternative to the theoretical scavenging models. Future development of size-resolved impaction scavenging models needs to include more precipitation properties (e.g., droplet surface area) and to be evaluated by detailed cloud microphysical models and available measurements. Several recently developed nucleation scavenging parameterizations for in-cloud removal of interstitial aerosol give comparable results when evaluated against parcel models; however, they need to be verified once suitable field measurements are available.More theoretical and field studies are also needed in order to better understand the role of organic aerosols in the nucleation scavenging process.

  18. Humpback Dolphins of Western Australia: A Review of Current Knowledge and Recommendations for Future Management.

    Science.gov (United States)

    Hanf, Daniella M; Hunt, Tim; Parra, Guido J

    2016-01-01

    Among the many cetacean species that occupy Australian coastal waters, Australian humpback dolphins, Sousa sahulensis, are one of the most vulnerable to extirpation due to human activities. This review summarises the existing knowledge, presently occurring and planned research projects, and current conservation measures for humpback dolphins in Western Australia (WA). Rapid and wide-scale coastal development along the northern WA coastline has occurred despite a lack of baseline data for inshore dolphins and, therefore, without a precautionary approach to their conservation. The distribution, abundance, habitat use, and population structure of humpback dolphins remain poorly understood. Less than 1% of their inferred distribution has so far been studied to understand local population demography. The sparse data available suggest that WA humpback dolphins occur as localised populations in low numbers within a range of inshore habitats, including both clear and turbid coastal waters. Marine protected areas cover a third of their inferred distribution in WA, but the efficacy of these reserves in protecting local cetacean populations is unknown. There is a pressing need for coordination and collaboration among scientists, government agencies, industry bodies, Traditional Owners, and local community groups to fill in the gaps of information on humpback dolphins in WA. The recently developed strategies and sampling guidelines developed by state and federal governments should serve as a best practise standard for collection of data aimed at assessing the conservation status of humpback dolphins in WA and Australia.

  19. Adult-onset autoimmune diabetes: current knowledge and implications for management.

    Science.gov (United States)

    Buzzetti, Raffaella; Zampetti, Simona; Maddaloni, Ernesto

    2017-09-08

    Adult-onset autoimmune diabetes is a heterogeneous disease that is characterized by a reduced genetic load, a less intensive autoimmune process and a mild metabolic decompensation at onset compared with young-onset type 1 diabetes mellitus (T1DM). The majority of patients with adult-onset autoimmune diabetes do not require insulin treatment for at least 6 months after diagnosis. Such patients are defined as having latent autoimmune diabetes in adults (LADA), which is distinct from classic adult-onset T1DM. The extensive heterogeneity of adult-onset autoimmune diabetes is apparent beyond the distinction between classic adult-onset T1DM and LADA. LADA is characterized by genetic, phenotypic and humoral heterogeneity, encompassing different degrees of insulin resistance and autoimmunity; this heterogeneity is probably a result of different pathological mechanisms, which have implications for treatment. The existence of heterogeneous phenotypes in LADA makes it difficult to establish an a priori treatment algorithm, and therefore, a personalized medicine approach is required. In this Review, we discuss the current understanding and gaps in knowledge regarding the pathophysiology and clinical features of adult-onset autoimmune diabetes and highlight the similarities and differences with classic T1DM and type 2 diabetes mellitus.

  20. Sugar transporters in efficient utilization of mixed sugar substrates: current knowledge and outlook.

    Science.gov (United States)

    Jojima, Toru; Omumasaba, Crispinus A; Inui, Masayuki; Yukawa, Hideaki

    2010-01-01

    There is increasing interest in production of transportation fuels and commodity chemicals from lignocellulosic biomass, most desirably through biological fermentation. Considerable effort has been expended to develop efficient biocatalysts that convert sugars derived from lignocellulose directly to value-added products. Glucose, the building block of cellulose, is the most suitable fermentation substrate for industrial microorganisms such as Escherichia coli, Corynebacterium glutamicum, and Saccharomyces cerevisiae. Other sugars including xylose, arabinose, mannose, and galactose that comprise hemicellulose are generally less efficient substrates in terms of productivity and yield. Although metabolic engineering including introduction of functional pentose-metabolizing pathways into pentose-incompetent microorganisms has provided steady progress in pentose utilization, further improvements in sugar mixture utilization by microorganisms is necessary. Among a variety of issues on utilization of sugar mixtures by the microorganisms, recent studies have started to reveal the importance of sugar transporters in microbial fermentation performance. In this article, we review current knowledge on diversity and functions of sugar transporters, especially those associated with pentose uptake in microorganisms. Subsequently, we review and discuss recent studies on engineering of sugar transport as a driving force for efficient bioconversion of sugar mixtures derived from lignocellulose.

  1. Role of Arbuscular Mycorrhizal Fungi in the Nitrogen Uptake of Plants: Current Knowledge and Research Gaps

    Directory of Open Access Journals (Sweden)

    Heike Bücking

    2015-12-01

    Full Text Available Arbuscular mycorrhizal (AM fungi play an essential role for the nutrient uptake of the majority of land plants, including many important crop species. The extraradical mycelium of the fungus takes up nutrients from the soil, transfers these nutrients to the intraradical mycelium within the host root, and exchanges the nutrients against carbon from the host across a specialized plant-fungal interface. The contribution of the AM symbiosis to the phosphate nutrition has long been known, but whether AM fungi contribute similarly to the nitrogen nutrition of their host is still controversially discussed. However, there is a growing body of evidence that demonstrates that AM fungi can actively transfer nitrogen to their host, and that the host plant with its carbon supply stimulates this transport, and that the periarbuscular membrane of the host is able to facilitate the active uptake of nitrogen from the mycorrhizal interface. In this review, our current knowledge about nitrogen transport through the fungal hyphae and across the mycorrhizal interface is summarized, and we discuss the regulation of these pathways and major research gaps.

  2. Influence of Electric, Magnetic, and Electromagnetic Fields on the Circadian System: Current Stage of Knowledge

    Directory of Open Access Journals (Sweden)

    Bogdan Lewczuk

    2014-01-01

    Full Text Available One of the side effects of each electrical device work is the electromagnetic field generated near its workplace. All organisms, including humans, are exposed daily to the influence of different types of this field, characterized by various physical parameters. Therefore, it is important to accurately determine the effects of an electromagnetic field on the physiological and pathological processes occurring in cells, tissues, and organs. Numerous epidemiological and experimental data suggest that the extremely low frequency magnetic field generated by electrical transmission lines and electrically powered devices and the high frequencies electromagnetic radiation emitted by electronic devices have a potentially negative impact on the circadian system. On the other hand, several studies have found no influence of these fields on chronobiological parameters. According to the current state of knowledge, some previously proposed hypotheses, including one concerning the key role of melatonin secretion disruption in pathogenesis of electromagnetic field induced diseases, need to be revised. This paper reviews the data on the effect of electric, magnetic, and electromagnetic fields on melatonin and cortisol rhythms—two major markers of the circadian system as well as on sleep. It also provides the basic information about the nature, classification, parameters, and sources of these fields.

  3. Transmission routes of African swine fever virus to domestic pigs: current knowledge and future research directions.

    Science.gov (United States)

    Guinat, Claire; Gogin, Andrey; Blome, Sandra; Keil, Guenther; Pollin, Reiko; Pfeiffer, Dirk U; Dixon, Linda

    2016-03-12

    African swine fever (ASF) is a major threat to the pig industry in Europe. Since 2007, ASF outbreaks have been ongoing in the Caucasus, Eastern Europe and the Baltic countries, causing severe economic losses for many pig farmers and pork producers. In addition, the number of ASF cases in wild boar populations has dramatically increased over the past few years. Evidence supports direct contact with infectious domestic pigs and wild boars, and consumption of contaminated feed, as the main transmission routes of ASF virus (ASFV) to domestic pigs. However, significant knowledge gaps highlight the urgent need for research to investigate the dynamics of indirect transmission via the environment, the minimal infective doses for contaminated feed ingestion, the probability of effective contacts between infectious wild boars and domestic pigs, the potential for recovered animals to become carriers and a reservoir for transmission, the potential virus persistence within wild boar populations and the influence of human behaviour for the spread of ASFV. This will provide an improved scientific basis to optimise current interventions and develop new tools and strategies to reduce the risk of ASFV transmission to domestic pigs.

  4. The rings of Saturn: State of current knowledge and some suggestions for future studies

    Science.gov (United States)

    Cuzzi, J. N.

    1978-01-01

    The state of our current knowledge of the properties of the ring system as a whole, and of the particles individually, is assessed. Attention is primarily devoted to recent results and possibilities for exploration of the ring system by a Saturn orbiter. In particular, the infrared and microwave properties of the ring system are discussed. The behavior of the ring brightness is not well understood in the critical transition spectral region from approximately 100 micrometers to approximately 1 cm. Also, the dynamical behavior of the ring system is discussed. Recent theoretical studies show that ongoing dynamical effects continually affect the ring structure in azimuth (possibly producing the A ring brightness asymmetry) and in the vertical direction. Orbital spacecraft-based studies of the rings will offer several unique advantages and impact important cosmogonical questions. Bistatic radar studies and millimeter-wavelength spectrometer/radiometry will give particle sizes and composition limits needed to resolve the question of the density of the rings, and provide important boundary conditions on the state of Saturn's protoplanetary nebula near the time of planetary formation.

  5. Tropical forest responses to increasing [CO2]: current knowledge and opportunities for future research

    Energy Technology Data Exchange (ETDEWEB)

    Cernusak, Lucas [Australian National University, Canberra, Australia; Winter, Klaus [Smithsonian Tropical Research Institute; Dalling, James [University of Illinois, Urbana-Champaign; Holtum, Joseph [James Cook University; Jaramillo, Carlos [Smithsonian Tropical Research Institute; Korner, Christian [University of Basel; Leakey, Andrew D.B. [University of Illinois; Norby, Richard J [ORNL; Poulter, Benjamin [Laboratoire des Sciences du Climat et de l' Environement, France; Turner, Benjamin [Smithsonian Tropical Research Institute; Wright, S. Joseph [Smithsonian Tropical Research Institute

    2013-01-01

    Elevated atmospheric [CO2] (ca) will undoubtedly affect the metabolism of tropical forests worldwide; however, critical aspects of how tropical forests will respond remain largely unknown. Here we review the current state of knowledge about physiological and ecological responses, with the aim of providing a framework that can help to guide future experimental research. Modelling studies have indicated that elevated ca can potentially stimulate photosynthesis more in the tropics than at higher latitudes, because suppression of photorespiration by elevated ca increases with temperature. However, canopy leaves in tropical forests could also potentially reach a high temperature threshold under elevated ca that will moderate the rise in photosynthesis. Belowground responses, including fine root production, nutrient foraging, and soil organic matter processing, will be especially important to the integrated ecosystem response to elevated CO2. Water-use efficiency will increase as ca rises, potentially impacting upon soil moisture status and nutrient availability. Recruitment may be differentially altered for some functional groups, potentially decreasing ecosystem carbon storage. Whole-forest CO2 enrichment experiments are urgently needed to test predictions of tropical forest functioning under elevated ca. Smaller scale experiments in the understory and in gaps would also be informative, and could provide stepping stones toward stand-scale manipulations.

  6. Role of lung surfactant in respiratory disease: current knowledge in large animal medicine.

    Science.gov (United States)

    Christmann, U; Buechner-Maxwell, V A; Witonsky, S G; Hite, R D

    2009-01-01

    Lung surfactant is produced by type II alveolar cells as a mixture of phospholipids, surfactant proteins, and neutral lipids. Surfactant lowers alveolar surface tension and is crucial for the prevention of alveolar collapse. In addition, surfactant contributes to smaller airway patency and improves mucociliary clearance. Surfactant-specific proteins are part of the innate immune defense mechanisms of the lung. Lung surfactant alterations have been described in a number of respiratory diseases. Surfactant deficiency (quantitative deficit of surfactant) in premature animals causes neonatal respiratory distress syndrome. Surfactant dysfunction (qualitative changes in surfactant) has been implicated in the pathophysiology of acute respiratory distress syndrome and asthma. Analysis of surfactant from amniotic fluid allows assessment of fetal lung maturity (FLM) in the human fetus and exogenous surfactant replacement therapy is part of the standard care in premature human infants. In contrast to human medicine, use and success of FLM testing or surfactant replacement therapy remain limited in veterinary medicine. Lung surfactant has been studied in large animal models of human disease. However, only a few reports exist on lung surfactant alterations in naturally occurring respiratory disease in large animals. This article gives a general review on the role of lung surfactant in respiratory disease followed by an overview of our current knowledge on surfactant in large animal veterinary medicine.

  7. Horizontal gene transfer among microorganisms in food: current knowledge and future perspectives.

    Science.gov (United States)

    Rossi, Franca; Rizzotti, Lucia; Felis, Giovanna E; Torriani, Sandra

    2014-09-01

    The possibility of horizontal gene transfer (HGT) among microorganisms in food matrices has been specifically targeted in a few investigations, though most current knowledge has been obtained indirectly or derived from genome sequence analyses. In this review, we have assembled reported examples of the HGT events that probably occurred in food matrices since the bacterial partners involved are commonly found in association in a food matrix or are specifically adapted to it. Exchanged genes include those encoding for substrate utilization, bacteriocin, exopolysaccharide and biogenic amine (BA) production, immunity to bacteriophages and antibiotic resistance (AR). While the acquisition of new traits involved in substrate utilization led to the natural genetic improvement of the microbial cultures for food production, the acquisition of hazardous traits, e.g., AR, virulence or BA production genes, can give rise to health concerns in otherwise innocuous species. Available evidence suggests that it would be opportune to determine what conditions favour HGT among bacteria in food ecosystems in order to naturally obtain improved starter or adjunct cultures, and also to prevent the propagation of hazardous traits.

  8. Epidemiology of leishmaniasis in Ecuador: current status of knowledge - A review

    Directory of Open Access Journals (Sweden)

    Manuel Calvopina

    2004-11-01

    Full Text Available Although leishmaniasis is regarded as a significant health problem in Ecuador by the Ministry of Health, and the incidence has increased over the last years, an official map on the geographic distribution of disease and sand fly vectors or a control strategy do not exist yet. This article reviews the current situation based on published information to improve our knowledge and understand the epidemiological situation of leishmaniasis in Ecuador in order to help future research and to develop a national control strategy. The disease is endemic in most provinces throughout Pacific coastal region, Amazonian lowlands, and some inter-Andean valleys with a total 21,805 cases reported during 1990-2003. Whereas cutaneous leishmaniasis (CL is found throughout Ecuador, mucocutaneous leishmaniasis (MCL appears to be restricted to the Amazon region; one, parasitologically unconfirmed case of visceral form was reported in 1949. Most human infections are caused by Leishmania (Viannia spp., which is distributed in the subtropical and tropical lowlands; infections due to L. (Leishmania spp. are found in the Andean highlands and in the Pacific lowlands as well. The proven vectors are Lutzomyia trapidoi and Lu. ayacuchensis. Canis familiaris, Sciurus vulgaris, Potos flavus, and Tamandua tetradactyla have been found infected with Leishmania spp. It is estimated that around 3000-4500 people may be infected every year, and that 3.1 to 4.5 millions people are estimated to be at risk of contracting leishmaniasis.

  9. Health-Related Fitness Knowledge and Physical Activity of High School Students

    Science.gov (United States)

    Thompson, Angela; Hannon, James C.

    2012-01-01

    The purpose of this study was to determine if health-related fitness (HRF) knowledge is related to self-reported physical activity (PA) of high school students. Students (N=165) enrolled in physical education from two schools in the Southwestern U.S participated. A 100-point HRF knowledge test was assembled, focusing on the HRF concepts of…

  10. Mindfulness and integrative self-knowledge: relationships with health-related variables.

    Science.gov (United States)

    Ghasemipour, Yadollah; Robinson, Julie Ann; Ghorbani, Nima

    2013-01-01

    This study examined how mindfulness and integrative self-knowledge were related to health-related issues. Men in general population (n = 103) and coronary heart disease samples (n = 101) completed the Mindful Attention Awareness Scale, the Integrative Self-knowledge Scale, the Type 2 subscale of the Interpersonal Reactions Inventory, the Perceived Stress Scale, and the Anxiety and Depression Scales. In both samples, there was a moderate positive correlation between mindfulness and integrative self-knowledge and they were negatively correlated with all health-related variables. However, only integrative self-knowledge explained independent variance in health-related variables. Specifically, in both samples, the relationship between mindfulness and health-related variables was mediated by integrative self-knowledge. Mindfulness and integrative self-knowledge are related domains of self-awareness that are associated with a range of health-related variables. These relationships are robust across samples drawn from general population and patients with coronary heart disease. The finding that integrative self-knowledge explained additional variance in the health-related variables after the contribution of mindfulness had been accounted for suggests that reflective self-awareness in integrative self-knowledge may make a unique contribution to the explanation of individual differences in health variables.

  11. Early life determinants of physical activity and sedentary time: Current knowledge and future research

    Directory of Open Access Journals (Sweden)

    Guro Pauck Øglund

    2014-12-01

    Full Text Available Previous findings of the association between low birth weight and subsequent health outcomes have led to the “developmental origins of health and disease hypothesis”. Furthermore, modifiable and partly modifiable early life factors may also influence behaviors such as physical activity and sedentary behavior. The aim of the present review was to summarize the existing knowledge on early life determinants (birth weight, rapid infant weight gain, motor development and infant temperament of childhood physical activity and sedentary time, and suggest opportunities for future research based on the Mother and Child Cohort Study (MoBa. Inconsistent results have been observed when relating birth weight to later physical activity, likely explained by differences in methodology when assessing physical activity between studies. There is limited data on whether rapid weight gain in early life predicts later physical activity and few studies have examined the association between birth weight and infant weight gain with subsequent sedentary time. Motor development may be a predictor for childhood physical activity, however methodological limitations preclude firm conclusions. The association between motor development and sedentary time has rarely been examined. Conflicting results have been reported for the association between infant temperament and subsequent physical activity and sedentary time in toddlers. Finally, it is unknown whether physical activity modifies the association between birth weight, postnatal weight gain, and later health outcomes in youth. Additional research in well-characterized birth cohorts can be used to generate new knowledge on possible early life determinants of children’s and youth’s physical activity and sedentary time which may inform evidence-based public health interventions.

  12. Assessment of nutrition knowledge and related aspects among first-year Kuwait University students.

    Science.gov (United States)

    El-Sabban, Farouk; Badr, Hanan E

    2011-01-01

    Assessing nutrition knowledge of populations assists in drawing strategies for education programs. Nutrition-related problems are common in Kuwait, thus data on nutrition knowledge are needed. This study involved administration of a questionnaire to 1,037 first-year Kuwait University students. The overall nutrition knowledge score was rated as fair, with deficiency in specific areas of knowledge. Students' dietary habits, attitudes, and interest in nutrition information were assessed as fair. Our findings will aid in building a nutrition knowledge database in Kuwait. A simplified course on aspects of healthy nutrition and lifestyle to all Kuwait University students is highly recommended.

  13. Estado de conocimiento del orden Ephemeroptera en la Patagonia Current knowledge of Patagonian Ephemeroptera

    Directory of Open Access Journals (Sweden)

    Pablo Pessacq

    2009-06-01

    Full Text Available El conocimiento actual del orden Ephemeroptera en la Patagonia se debe en gran parte a la labor original y compilatoria de M.L. Pescador, W.L. Peters y E. Domínguez, llevada a cabo en la década del 80 del siglo pasado. Se suman a ésta, importantes contribuciones que han conducido a un adecuado conocimiento del grupo en la cordillera norte y centro de la Patagonia, aunque menor en la zona austral de esta región (Santa Cruz y Tierra del Fuego y las áreas de estepa. Merced al trabajo de campo realizado en 80 sitios de muestreo relevados en el marco del "Darwin Initiative Project" en el Parque Nacional Nahuel Huapi, se incluyen aquí nuevos registros para la Argentina (Hapsiphlebia anastomosis Demoulin, la región Andina (Apobaetis Day y la provincia de Río Negro (Chaquihua bullocki (Navás, Andesiops ardua (Lugo-Ortíz & McCafferty, Murphyella needhami Lestage y Dactylophlebia carnulenta Pescador & Peters. Con estos registros, la riqueza de Ephemeroptera de la Patagonia alcanza 43 especies y 24 géneros, de las cuales 33 (en 20 géneros se conocen para la Argentina.The current knowledge of the Patagonian Ephemeroptera is due to the original and compiling work by M.L. Pescador, W.L. Peters and E. Domínguez during last Century's 80´s . Besides, other previous publications exist that contributed to achieve a reasonable knowledge of its taxonomy for the norhtern and central Patagonian Andes, though poor for the southernmost mountain areas (Santa Cruz and Tierra del Fuego provinces and the steppe. From the field work carried in 80 collecting sites during the development of the "Darwin Initiative Project" in the Nahuel Huapi Nacional Park, some species are recorded for the first time in Argentina (Hapsiphlebia anastomosis Demoulin, the Andean region (Apobaetis Day and the province of Río Negro (Chaquihua bullock (Navás, Andesiops ardua (Lugo-Ortíz & McCafferty, Murphyella needhami Lestage, Dactylophlebia carnulenta Pescador & Peters. With

  14. THE EFFECT OF KNOWLEDGE ECONOMY ON THE MANAGEMENT AND LABOR RELATIONS

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    With the emergence of Knowledge Economy and its penetration intoevery aspect of society,many industrial functions have been changing,including management and labor relations.In this paper,the author first presents a system view of management and labor relations under Knowledge Economy,and then based on it,elaborates on effect of Knowledge Economy on them,using the case of HP as demonstration.In the end,conclusion is made that new dynamic equilibration will develop,depending upon the dynamic power contrast of the above two subjects under dynamic changing circumstances of Knowledge Economy.

  15. Community Knowledge about Water: Who Has Better Knowledge and Is This Associated with Water-Related Behaviors and Support for Water-Related Policies?

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    Angela J Dean

    Full Text Available Sustainable approaches to water management require broad community acceptance of changes in policy, practice and technology, which in turn, requires an engaged community. A critical first step in building an engaged community is to identify community knowledge about water management, an issue rarely examined in research. To address this, we surveyed a representative sample of Australian adults (n = 5172. Knowledge was assessed using 15 questions about impact of household activities on waterways, the urban water cycle, and water management. This survey also examined demographics, psychosocial characteristics, exposure to water-related information, and water-related behaviors and policy support. Participants correctly answered a mean of 8.0 questions (Range 0-15. Most respondents knew that household actions can reduce water use and influence waterway health, whereas less than one third correctly identified that domestic wastewater is treated prior to entering waterways, urban stormwater is not treated, and that these are carried via different pipes. Higher water knowledge was associated with older age, higher education and living in non-urban areas. Poorer water knowledge was associated with speaking a language other than English in the home. Garden size, experience of water restrictions, satisfaction, waterway use for swimming, and certain information sources were also associated with knowledge. Greater water knowledge was associated with adoption of water-saving and pollution-reduction behaviors, and support for both alternative water sources and raingardens. These findings confirm the importance of community knowledge, and identify potential subgroups who may require additional targeting to build knowledge and support for water management initiatives.

  16. Examine the Gaps between Current and Ideal State of Knowledge Management in the Department of Physical Education

    Directory of Open Access Journals (Sweden)

    Kaveh Hasani

    2013-02-01

    Full Text Available In today's competitive world, knowledge has become the strategic resource in many organizations. Nonaka believes that in today's volatile situation, the only viable source of sustainable competitive advantage is knowledge. Thus, the knowledge management has become a major task for organizations that are looking to take advantage of this valuable asset. In this case the goal of this study is to examine the gaps between current and ideal state of knowledge management in the Department of Physical Education in Iran. Research's method was descriptive-menstruation. Study sample consisted of all employees of the Department of Physical Education of Kurdistan that were 320 members and it was selected by using Morgan table that were 175 members. The reliability of the questionnaire was measured and verified based on Cronbach's Alpha for the knowledge management dimension equals 0/89. Also a questionnaire to be standardized and be normalized in internal research, ensure validity of test. Used statistical methods in current study is use SPSS software and descriptive statistics to describe sex, age, education level and staff's job precedence variables and Kolmogorov – Smirnov test (K-S to verify data to be normal and to verify or reject hypothesis, Paired t-test is been used. Research results showed, there are meaningful differences among knowledge management Dimensions, including Technology infrastructure, organizational culture and organizational structure from the perspective of the Kurdistan's physical education staff in current situation with the ideal situation.

  17. Sports-related concussions: diagnosis, complications, and current management strategies.

    Science.gov (United States)

    Hobbs, Jonathan G; Young, Jacob S; Bailes, Julian E

    2016-04-01

    Sports-related concussions (SRCs) are traumatic events that affect up to 3.8 million athletes per year. The initial diagnosis and management is often instituted on the field of play by coaches, athletic trainers, and team physicians. SRCs are usually transient episodes of neurological dysfunction following a traumatic impact, with most symptoms resolving in 7-10 days; however, a small percentage of patients will suffer protracted symptoms for years after the event and may develop chronic neurodegenerative disease. Rarely, SRCs are associated with complications, such as skull fractures, epidural or subdural hematomas, and edema requiring neurosurgical evaluation. Current standards of care are based on a paradigm of rest and gradual return to play, with decisions driven by subjective and objective information gleaned from a detailed history and physical examination. Advanced imaging techniques such as functional MRI, and detailed understanding of the complex pathophysiological process underlying SRCs and how they affect the athletes acutely and long-term, may change the way physicians treat athletes who suffer a concussion. It is hoped that these advances will allow a more accurate assessment of when an athlete is truly safe to return to play, decreasing the risk of secondary impact injuries, and provide avenues for therapeutic strategies targeting the complex biochemical cascade that results from a traumatic injury to the brain.

  18. Treatment of neovascular age-related macular degeneration: Current therapies

    Directory of Open Access Journals (Sweden)

    Albert J Augustin

    2009-01-01

    Full Text Available Albert J Augustin, Stefan Scholl, Janna KirchhofDepartment of Ophthalmology, Klinikum Karlsruhe, GermanyAbstract: Choroidal neovascularization (CNV secondary to age-related macular degeneration (AMD is now the leading cause of blindness and severe vision loss among people over the age of 40 in the Western world. Its prevalence is certain to increase substantially as the population ages. Treatments currently available for the disease include laser photocoagulation, verteporfin photodynamic therapy, and intravitreal injections of corticosteroids and anti-angiogenic agents. Many studies have reported the benefits of each of these treatments, although none is without its risks. No intervention actually cures AMD, nor the neovascularization associated with it. However, its symptoms are treated with varying degrees of success. Some treatments stabilize or arrest the progress of the disease. Others have been shown to reverse some of the damage that has already been done. These treatments can even lead to visual improvement. This paper will review the major classes of drugs and therapies designed to treat this condition.Keywords: wet AMD, neovascularization, PDT, steroids, anti-angiogenesis

  19. Synthesis of current knowledge on post-fire seeding for soil stabilization and invasive species control

    Science.gov (United States)

    Beyers, Jan L.; Pyke, David A.; Wirth, Troy

    2015-01-01

    The General Accounting Office has identified a need for better information on the effectiveness of post-fire emergency stabilization and rehabilitation methods used by the U.S. Forest Service and Department of Interior (DOI) agencies. Since reviews were published on treatment effectiveness in the early 2000s, treatment choices have changed and increased monitoring has been done. Greater use of native species has added substantially to burned area emergency response (BAER) treatment costs, for example, but quantitative data on this treatment were scarce in earlier reviews. We synthesized current information on the effectiveness of post-fire seeding for both soil stabilization and for prevention of the spread of invasive species in rangelands. We reviewed published literature (peer-reviewed and “gray”) and agency monitoring reports, as well as compiled and analyzed quantitative data in agency files. Products of this review include a web-accessible database of monitoring reports and published information, a scientific journal paper summarizing findings of scientific studies, an annotated bibliography of peer-reviewed papers, a summary report published as a General Technical Report that will be available online (in progress), and presentations to scientific meetings and BAER/ESR team training sessions and workshops. By combining results from studies done by Forest Service and DOI agency personnel with research studies published since the initial reviews, we presented a comprehensive synthesis of seeding effectiveness knowledge that complements the review of other hillslope treatments published by other researchers. This information will help federal land managers make more cost-effective decisions on post-fire stabilization and rehabilitation treatments.

  20. Current knowledge of tooth development: patterning and mineralization of the murine dentition.

    Science.gov (United States)

    Catón, Javier; Tucker, Abigail S

    2009-04-01

    The integument forms a number of different types of mineralized element, including dermal denticles, scutes, ganoid scales, elasmoid scales, fin rays and osteoderms found in certain fish, reptiles, amphibians and xenarthran mammals. To this list can be added teeth, which are far more widely represented and studied than any of the other mineralized elements mentioned above, and as such can be thought of as a model mineralized system. In recent years the focus for studies on tooth development has been the mouse, with a wealth of genetic information accrued and the availability of cutting edge techniques. It is the mouse dentition that this review will concentrate on. The development of the tooth will be followed, looking at what controls the shape of the tooth and how signals from the mesenchyme and epithelium interact to lead to formation of a molar or incisor. The number of teeth generated will then be investigated, looking at how tooth germ number can be reduced or increased by apoptosis, fusion of tooth germs, creation of new tooth germs, and the generation of additional teeth from existing tooth germs. The development of mineralized tissue will then be detailed, looking at how the asymmetrical deposition of enamel is controlled in the mouse incisor. The continued importance of epithelial-mesenchymal interactions at these later stages of tooth development will also be discussed. Tooth anomalies and human disorders have been well covered by recent reviews, therefore in this paper we wish to present a classical review of current knowledge of tooth development, fitting together data from a large number of recent research papers to draw general conclusions about tooth development.

  1. Genetic considerations for mollusc production in aquaculture: current state of knowledge.

    Directory of Open Access Journals (Sweden)

    Marcela eAstorga

    2014-12-01

    Full Text Available IIn 2012, world mollusk production in aquaculture reached a volume of 15,171,000 tons, representing 23% of total aquaculture production and positioning mollusks as the second most important category of aquaculture products (fishes are the first. Clams and oysters are the mollusk species with the highest production levels, followed in descending order by mussels, scallops and abalones. In view of the increasing importance attached to genetic information on aquaculture, which can help with good maintenance and thus the sustainability of production, the present work offers a review of the state of knowledge on genetic and genomic information about mollusks produced in aquaculture. The analysis was applied to mollusks which are of importance for aquaculture, with emphasis on the 5 species with the highest production levels. According to FAO, these are: Japanese clam Ruditapes philippinarum; Pacific oyster Crassostrea gigas; Chilean mussel Mytilus chilensis; Blood clam Anadara granosa and Chinese clam Sinonovacula constricta. To date, the genomes of 5 species of mollusks have been sequenced, only one of which, Crassostrea gigas, coincides with the species with the greatest production in aquaculture. Another important species whose genome has been sequenced is Mytilus galloprovincialis, which is the second most important mussel in aquaculture production, after M. chilensis. Few genetic improvement programs have been reported in comparison with the number reported in fish species. The most commonly investigated species are oysters, with at least 5 genetic improvement programs reported, followed by abalones with 2 programs and mussels with one. The results of this work will establish the current situation with respect to the genetics of mollusks which are of importance for aquaculture production, in order to assist future decisions to ensure the sustainability of these resources.

  2. Age-related variations of visuo-motor adaptation beyond explicit knowledge

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    Herbert eHeuer

    2014-07-01

    Full Text Available Visuo-motor adaptation suffers at older working age. The age-related decline of behavioural adjustments is accompanied by reduced explicit knowledge of the visuo-motor transformation. It disappears when explicit knowledge is kept constant across the age range, except for particularly high levels of explicit knowledge. According to these findings, at older adult age both the acquisition of explicit knowledge and its application for strategic corrections become poorer. Recently it has been posited that visuo-motor adaptation can involve model-free reinforcement mechanisms of learning in addition to model-based mechanisms. We tested whether age-related declines of reinforcement learning can also contribute to the age-related changes of visuo-motor adaptation. Therefore we enhanced the contribution of reinforcement learning to visuo-motor adaptation by way of introducing salient markers of success and failure during practice. With such modified practice conditions, there were residual age-related variations of behavioural adjustments at all levels of explicit knowledge, even when explicit knowledge was absent. The residual age-related variations were observed for practiced target directions only, but not for new target directions. These findings are consistent with an age-related decline of model-free reinforcement learning as a third factor in the age-related decline of visuo-motor adaptation. Under practice conditions, which spur model-free reward-based learning, this factor adds to the decrements of the acquisition of explicit knowledge and its use for strategic corrections.

  3. Short Round Sub-Linear Zero-Knowledge Argument for Linear Algebraic Relations

    Science.gov (United States)

    Seo, Jae Hong

    Zero-knowledge arguments allows one party to prove that a statement is true, without leaking any other information than the truth of the statement. In many applications such as verifiable shuffle (as a practical application) and circuit satisfiability (as a theoretical application), zero-knowledge arguments for mathematical statements related to linear algebra are essentially used. Groth proposed (at CRYPTO 2009) an elegant methodology for zero-knowledge arguments for linear algebraic relations over finite fields. He obtained zero-knowledge arguments of the sub-linear size for linear algebra using reductions from linear algebraic relations to equations of the form z = x *' y, where x, y ∈ Fnp are committed vectors, z ∈ Fp is a committed element, and *' : Fnp × Fnp → Fp is a bilinear map. These reductions impose additional rounds on zero-knowledge arguments of the sub-linear size. The round complexity of interactive zero-knowledge arguments is an important measure along with communication and computational complexities. We focus on minimizing the round complexity of sub-linear zero-knowledge arguments for linear algebra. To reduce round complexity, we propose a general transformation from a t-round zero-knowledge argument, satisfying mild conditions, to a (t - 2)-round zero-knowledge argument; this transformation is of independent interest.

  4. [Essential procedure and key methods for survey of traditional knowledge related to Chinese materia medica resources].

    Science.gov (United States)

    Cheng, Gong; Huang, Lu-qi; Xue, Da-yuan; Zhang, Xiao-bo

    2014-12-01

    The survey of traditional knowledge related to Chinese materia medica resources is the important component and one of the innovative aspects of the fourth national survey of the Chinese materia medica resources. China has rich traditional knowledge of traditional Chinese medicine (TCM) and the comprehensive investigation of TCM traditional knowledge aims to promote conservation and sustainable use of Chinese materia medica resources. Building upon the field work of pilot investigations, this paper introduces the essential procedures and key methods for conducting the survey of traditional knowledge related to Chinese materia medica resources. The essential procedures are as follows. First is the preparation phrase. It is important to review all relevant literature and provide training to the survey teams so that they have clear understanding of the concept of traditional knowledge and master key survey methods. Second is the field investigation phrase. When conducting field investigations, survey teams should identify the traditional knowledge holders by using the 'snowball method', record the traditional knowledge after obtaining prior informed concerned from the traditional knowledge holders. Researchers should fill out the survey forms provided by the Technical Specification of the Fourth National Survey of Chinese Materia Medica Resources. Researchers should pay particular attention to the scope of traditional knowledge and the method of inheriting the knowledge, which are the key information for traditional knowledge holders and potential users to reach mutual agreed terms to achieve benefit sharing. Third is the data compilation and analysis phrase. Researchers should try to compile and edit the TCM traditional knowledge in accordance with intellectual property rights requirements so that the information collected through the national survey can serve as the basic data for the TCM traditional knowledge database. The key methods of the survey include regional

  5. Current Research on the Relative Effectiveness of Selected Media Characteristics.

    Science.gov (United States)

    Gulliford, Nancy L.

    The literature of research and theory on media, the psychology of learning, and the technology of instruction is reviewed. The focus is on discovering what is currently known about the intersection of these fields. Current thoughts and discoveries about brain structure and processing are discussed. The management of learning as a system is another…

  6. HIV-Related Knowledge, Attitudes and Behaviours among College Students in China

    Science.gov (United States)

    Tung, Wei-Chen; Hu, Jie; Efird, Jimmy Thomas; Yu, Liping; Su, Wei

    2012-01-01

    Objectives: To assess the knowledge, attitudes, sources of HIV information and behaviours related to HIV, and to explore the difference in the HIV knowledge and attitudes between genders and school years among college students in China. Design: Descriptive, cross-sectional. Setting: 475 college students from two universities in China. Method: Data…

  7. Stroke-Related Knowledge, Lifestyle Behaviours and Health Beliefs in Singaporean Chinese: Implications for Health Education

    Science.gov (United States)

    Wong, Wai Pong; Yeung, Meredith; Loh, Susan; Lee, Mina; Ghazali, F.; Chan, C. J.; Feng, S.; Liew, Y. V.; Seah, P. F.; Wee, J.; Wang, J.; Huang, X.; Dean, Elizabeth

    2013-01-01

    Objective: The objective of the present study was to describe stroke-related knowledge (risk factors, warning signs and emergency response), lifestyle behaviours and health beliefs among Singaporean Chinese, and to identify any factors associated with such knowledge, behaviours and beliefs. Design: This was a cross-sectional study design employing…

  8. HIV-Related Knowledge, Attitudes and Behaviours among College Students in China

    Science.gov (United States)

    Tung, Wei-Chen; Hu, Jie; Efird, Jimmy Thomas; Yu, Liping; Su, Wei

    2012-01-01

    Objectives: To assess the knowledge, attitudes, sources of HIV information and behaviours related to HIV, and to explore the difference in the HIV knowledge and attitudes between genders and school years among college students in China. Design: Descriptive, cross-sectional. Setting: 475 college students from two universities in China. Method: Data…

  9. Secondary Teachers’ Mathematics-related Beliefs and Knowledge about Mathematical Problem-solving

    Science.gov (United States)

    E Siswono, T. Y.; Kohar, A. W.; Hartono, S.

    2017-02-01

    This study investigates secondary teachers’ belief about the three mathematics-related beliefs, i.e. nature of mathematics, teaching mathematics, learning mathematics, and knowledge about mathematical problem solving. Data were gathered through a set of task-based semi-structured interviews of three selected teachers with different philosophical views of teaching mathematics, i.e. instrumental, platonist, and problem solving. Those teachers were selected from an interview using a belief-related task from purposively selected teachers in Surabaya and Sidoarjo. While the interviews about knowledge examine teachers’ problem solving content and pedagogical knowledge, the interviews about beliefs examine their views on several cases extracted from each of such mathematics-related beliefs. Analysis included the categorization and comparison on each of beliefs and knowledge as well as their interaction. Results indicate that all the teachers did not show a high consistency in responding views of their mathematics-related beliefs, while they showed weaknesses primarily on problem solving content knowledge. Findings also point out that teachers’ beliefs have a strong relationship with teachers’ knowledge about problem solving. In particular, the instrumental teacher’s beliefs were consistent with his insufficient knowledge about problem-solving, while both platonist and problem-solving teacher’s beliefs were consistent with their sufficient knowledge of either content or pedagogical problem solving.

  10. Effect of Dairy Beef Quality Assurance Training on Dairy Worker Knowledge and Welfare-Related Practices

    Science.gov (United States)

    Adams, Ashley E.; Ahola, Jason K.; Chahine, Mireille; Roman-Muniz, I. Noa

    2016-01-01

    A study was conducted to determine whether on-farm dairy beef quality assurance (BQA) training affected dairy worker knowledge of BQA and welfare-related practices. Dairy personnel who participated in the BQA training were administered an exam before and after the training to gauge the amount of knowledge gained. The average exam score was 21.0…

  11. Developmental Relations between Vocabulary Knowledge and Reading Comprehension: A Latent Change Score Modeling Study

    Science.gov (United States)

    Quinn, Jamie M.; Wagner, Richard K.; Petscher, Yaacov; Lopez, Danielle

    2015-01-01

    The present study followed a sample of first-grade (N = 316, M[subscript age] = 7.05 at first test) through fourth-grade students to evaluate dynamic developmental relations between vocabulary knowledge and reading comprehension. Using latent change score modeling, competing models were fit to the repeated measurements of vocabulary knowledge and…

  12. An Analysis of the Candidate Teachers' Beliefs Related to Knowledge, Learning and Teaching

    Science.gov (United States)

    Bay, Erdal; Vural, Ömer Faruk; Demir, Servet; Bagceci, Birsen

    2015-01-01

    Candidate teachers have several beliefs related to their knowledge, learning and teaching. The purpose of this study is to analyze the beliefs of candidate teachers about knowledge, learning and teaching. Candidate teachers were assigned a scale and from the answers "belief points" were obtained based on their attitudes about these three…

  13. Developmental Relations between Vocabulary Knowledge and Reading Comprehension: A Latent Change Score Modeling Study

    Science.gov (United States)

    Quinn, Jamie M.; Wagner, Richard K.; Petscher, Yaacov; Lopez, Danielle

    2015-01-01

    The present study followed a sample of first-grade (N = 316, M[subscript age] = 7.05 at first test) through fourth-grade students to evaluate dynamic developmental relations between vocabulary knowledge and reading comprehension. Using latent change score modeling, competing models were fit to the repeated measurements of vocabulary knowledge and…

  14. Stroke-Related Knowledge, Lifestyle Behaviours and Health Beliefs in Singaporean Chinese: Implications for Health Education

    Science.gov (United States)

    Wong, Wai Pong; Yeung, Meredith; Loh, Susan; Lee, Mina; Ghazali, F.; Chan, C. J.; Feng, S.; Liew, Y. V.; Seah, P. F.; Wee, J.; Wang, J.; Huang, X.; Dean, Elizabeth

    2013-01-01

    Objective: The objective of the present study was to describe stroke-related knowledge (risk factors, warning signs and emergency response), lifestyle behaviours and health beliefs among Singaporean Chinese, and to identify any factors associated with such knowledge, behaviours and beliefs. Design: This was a cross-sectional study design employing…

  15. Relation of the auroral substorm to the substorm current wedge

    Science.gov (United States)

    McPherron, Robert L.; Chu, Xiangning

    2016-12-01

    The auroral substorm is an organized sequence of events seen in the aurora near midnight. It is a manifestation of the magnetospheric substorm which is a disturbance of the magnetosphere brought about by the solar wind transfer of magnetic flux from the dayside to the tail lobes and its return through the plasma sheet to the dayside. The most dramatic feature of the auroral substorm is the sudden brightening and poleward expansion of the aurora. Intimately associated with this expansion is a westward electrical current flowing across the bulge of expanding aurora. This current is fed by a downward field-aligned current (FAC) at its eastern edge and an upward current at its western edge. This current system is called the substorm current wedge (SCW). The SCW forms within a minute of auroral expansion. FAC are created by pressure gradients and field line bending from shears in plasma flow. Both of these are the result of pileup and diversion of plasma flows in the near-earth plasma sheet. The origins of these flows are reconnection sites further back in the tail. The auroral expansion can be explained by a combination of a change in field line mapping caused by the substorm current wedge and a tailward growth of the outer edge of the pileup region. We illustrate this scenario with a complex substorm and discuss some of the problems associated with this interpretation.

  16. Skin Wound Healing: An Update on the Current Knowledge and Concepts.

    Science.gov (United States)

    Sorg, Heiko; Tilkorn, Daniel J; Hager, Stephan; Hauser, Jörg; Mirastschijski, Ursula

    2017-01-01

    repair have been delineated in part, many underlying pathophysiological processes are still unknown. The purpose of the following update on skin wound healing is to focus on the different phases and to brief the reader on the current knowledge and new insights. Skin wound healing is a complex process, which is dependent on many cell types and mediators interacting in a highly sophisticated temporal sequence. Although some interactions during the healing process are crucial, redundancy is high and other cells or mediators can adopt functions or signaling without major complications. © 2016 S. Karger AG, Basel.

  17. Current state of knowledge in microbial degradation of polycyclic aromatic hydrocarbons (PAHs: a review

    Directory of Open Access Journals (Sweden)

    Debajyoti Ghosal

    2016-08-01

    PAHs. The main purpose of this review is to provide an overview of current knowledge of bacteria, halophilic archaea, fungi and algae mediated degradation/transformation of PAHs. In addition, factors affecting PAHs degradation in the environment, recent advancement in genetic, genomic, proteomic and metabolomic techniques are also highlighted with an aim to facilitate the development of a new insight into the bioremediation of PAH in the environment.

  18. Current State of Knowledge in Microbial Degradation of Polycyclic Aromatic Hydrocarbons (PAHs): A Review

    Science.gov (United States)

    Ghosal, Debajyoti; Ghosh, Shreya; Dutta, Tapan K.; Ahn, Youngho

    2016-01-01

    purpose of this review is to provide an overview of current knowledge of bacteria, halophilic archaea, fungi and algae mediated degradation/transformation of PAHs. In addition, factors affecting PAHs degradation in the environment, recent advancement in genetic, genomic, proteomic and metabolomic techniques are also highlighted with an aim to facilitate the development of a new insight into the bioremediation of PAH in the environment. PMID:27630626

  19. Current State of Knowledge in Microbial Degradation of Polycyclic Aromatic Hydrocarbons (PAHs): A Review.

    Science.gov (United States)

    Ghosal, Debajyoti; Ghosh, Shreya; Dutta, Tapan K; Ahn, Youngho

    2016-01-01

    purpose of this review is to provide an overview of current knowledge of bacteria, halophilic archaea, fungi and algae mediated degradation/transformation of PAHs. In addition, factors affecting PAHs degradation in the environment, recent advancement in genetic, genomic, proteomic and metabolomic techniques are also highlighted with an aim to facilitate the development of a new insight into the bioremediation of PAH in the environment.

  20. Obesity risk knowledge, weight misperception and diet and health-related attitudes among women intending to become pregnant

    Science.gov (United States)

    BERENSON, Abbey B.; POHLMEIER, Ali M.; LAZ, Tabassum H.; RAHMAN, Mahbubur; SAADE, George

    2015-01-01

    Objective To evaluate obesity risk knowledge, weight misperception and diet and health-related attitudes among women intending to become pregnant compared to those not intending to become pregnant. Study Design Cross-sectional survey of health behaviors including obesity risk knowledge, weight misperception, and diet and health-related attitudes among women (16-40 years) attending reproductive health clinics in southeast Texas. Data were collected through self-administered questionnaires and chart review. Multivariable logistic regression analyses were performed to examine the association between pregnancy intention and obesity risk knowledge, weight misperception and health-related attitudes after adjusting for age, race, income and gravidity. Results Overall, 1,726 women completed the survey of which 1,420 responded to a question on pregnancy intention. Of these, 126 stated they were intending to become pregnant. Obesity risk knowledge (adjusted odds ratio [aOR] 1.14, 95% confidence interval [CI] 0.74-1.77) and weight misperception (aOR 1.17, 95% CI 0.75-1.83) did not differ between women intending and not intending to become pregnant. Additionally, diet and health-related attitudes did not differ between these two groups (P>0.05 for all). Among women intending to become pregnant, 51% had low obesity risk knowledge and 31% misperceived their body weight. Further, 76% of these women felt confused about what constitutes a healthy diet, although 47% believed that their current diet was healthy and saw no reason to change their current eating patterns. While weight misperception did not differ significantly between the two groups, overweight women intending to become pregnant were more likely to misperceive their weight than obese women intending to become pregnant (71% vs 10%, Ppregnant, regarding the risks associated with being overweight or obese, misperception of body weight, and negative diet and health-related attitudes. PMID:26099687

  1. A review on current knowledge and future prospects of organohalogen contaminants (OHCs) in Asian birds.

    Science.gov (United States)

    Abbasi, Naeem Akhtar; Malik, Riffat Naseem; Frantz, Adrien; Jaspers, Veerle Leontina Bernard

    2016-01-15

    The release of harmful chemicals in the Asian environment has recently increased dramatically due to rising industrial and agricultural activities. About 60% of the global human population is currently living on the Asian continent and may thus be exposed to a large range of different chemicals. Different classes of organohalogen chemicals have indeed been reported in various environmental compartments from Asia including humans and wildlife, but this issue has received less attention in birds. In this article, we reviewed the available literature on levels of legacy persistent organic pollutants (POPs) and various flame retardants (FRs) in Asian avifauna to analyze the existing pool of knowledge as well as to identify the gaps that should be addressed in future research. Furthermore, we discussed the variation in levels of organohalogens based on differences in regions, trophic level, dietary sources and migratory behaviors of species including distribution patterns in different tissues of birds. Although the mass of published literature is very low and even absent in many important regions of Asia, we deduced from the reported studies that levels of almost all classes of organohalogens (OHCs) including FRs were highest in East Asian countries such as Japan, China and South Korea, except for HCHs that were found at maximum levels in birds of South India. Concentrations (ng/g LW) of different OHCs in Asian birds ranged between

  2. Greek Primary School Teachers' Understanding of Current Environmental Issues: An Exploration of Their Environmental Knowledge and Images of Nature

    Science.gov (United States)

    Michail, Sirmo; Stamou, Anastasia G.; Stamou, George P.

    2007-01-01

    In this article, the Greek primary school teachers' understanding of three current environmental issues (acid rain, the ozone layer depletion, and the greenhouse effect) as well as the emerging images of nature were examined. The study revealed that teachers held several environmental knowledge gaps and misconceptions about the three phenomena.…

  3. Investigating Relationships among Pre-Service Science Teachers' Conceptual Knowledge of Electric Current, Motivational Beliefs and Self-Regulation

    Science.gov (United States)

    Inaltun, Hüseyin; Ates, Salih

    2015-01-01

    The purpose of this study is to examine relationships among pre-service science teachers' conceptual knowledge of electric current, motivational beliefs, and self-regulation. One hundred and twenty-seven students (female = 107, male = 20) enrolled in the science education program of a public university in Ankara participated the study. A concept…

  4. Greek Primary School Teachers' Understanding of Current Environmental Issues: An Exploration of Their Environmental Knowledge and Images of Nature

    Science.gov (United States)

    Michail, Sirmo; Stamou, Anastasia G.; Stamou, George P.

    2007-01-01

    In this article, the Greek primary school teachers' understanding of three current environmental issues (acid rain, the ozone layer depletion, and the greenhouse effect) as well as the emerging images of nature were examined. The study revealed that teachers held several environmental knowledge gaps and misconceptions about the three phenomena.…

  5. Investigating Relationships among Pre-Service Science Teachers' Conceptual Knowledge of Electric Current, Motivational Beliefs and Self-Regulation

    Science.gov (United States)

    Inaltun, Hüseyin; Ates, Salih

    2015-01-01

    The purpose of this study is to examine relationships among pre-service science teachers' conceptual knowledge of electric current, motivational beliefs, and self-regulation. One hundred and twenty-seven students (female = 107, male = 20) enrolled in the science education program of a public university in Ankara participated the study. A concept…

  6. Current and prospective pharmacological targets in relation to antimigraine action

    NARCIS (Netherlands)

    S. Mehrotra (Suneet); S. Gupta (Sanjay); K.Y. Chan (Kayi); C.M. Villalón (Carlos); D. Centurion (David); P.R. Saxena (Pramod Ranjan); A. Maassen van den Brink (Antoinette)

    2008-01-01

    textabstractMigraine is a recurrent incapacitating neurovascular disorder characterized by unilateral and throbbing headaches associated with photophobia, phonophobia, nausea, and vomiting. Current specific drugs used in the acute treatment of migraine interact with vascular receptors, a fact that h

  7. Relating Knowledge and Perceptions of Sustainable Water Management to Preferences for Smart Irrigation Technology

    National Research Council Canada - National Science Library

    Dong Hee Suh; Hayk Khachatryan; Alicia Rihn; Michael Dukes

    2017-01-01

    .... However, relatively little attention has been given toward understanding how homeowners’ perceptions and knowledge of smart irrigation technologies affect their preferences or stated purchase likelihood of such irrigation equipment...

  8. Mapping fire effects on ash and soil properties. Current knowledge and future perspectives.

    Science.gov (United States)

    Pereira, Paulo; Cerda, Artemi; Strielko, Irina

    2014-05-01

    floor consumption (Lewis et al., 2011), ash cover (Robichaud et al., 2007) and other aspects related with soil as the vegetation factors that affect post-fire erosion risk (Fox et al., 2008). Field studies had also indented to estimate and map the impacts of fire in soil properties. Contrary to remote sensing studies, the mapping of fire effects on ash and soil properties in the field is specially carried out at small scale (e.g. slope or plot). The small scale resolution studies are important because identify small patterns that are normally ignored by remote sensing studies, but fundamental to understand the post-fire evolution of the burned areas. One of the important aspects of the small scale studies of fire effect on ash and soil properties is the great spatial variability, showing that the impact of fire is extremely heterogeneous in space and time (Outeiro et al., 2008; Pereira et al. in press). The small scale mapping of fire effects on soil properties normally is carried out using Geostatistical methods or using deterministic interpolation methods (Robichaud and Miller, 1999; Pereira et al., 2013). Several reports were published on the spatial distribution and mapping of ash and duff thickness (Robichaud and Miller, 1999; Pereira et al., 2013; Pereira et al. in press), fire severity (Pereira et al., 2014), ash chemical characteristics as total nitrogen (Pereira et al., 2010a), and ash extractable elements (Pereira et al., 2010b). Also, previous works mapped fire effects on soil temperature (Gimeno-Garcia et al., 2004), soil hydrophobicity (Woods et al., 2007), total nitrogen (Hirobe et al., 2003), phosphorous (Rodriguez et al., 2009) and major cations (Outeiro et al., 2008). It is important to integrate remote sensing and field based works of fire effects on ash and soil properties in order to have a better validation of the models predicted. The aim of this work is present the current knowledge about mapping fire effects in ash and soil properties at diverse

  9. [Undesired awareness phenomena during general anesthesia: Evidence-based state of knowledge, current discussions and strategies for prevention and management].

    Science.gov (United States)

    Bischoff, P; Rundshagen, I; Schneider, G

    2015-10-01

    Patient awareness during general anesthesia and the later recall of what happened during surgery can be experienced by patients as horrifying events that leave lasting mental trauma in the form of posttraumatic stress syndrome (PTSS). Awareness is related to a temporary insufficient depth of anesthesia. This phenomenon has been discussed for more than 20 years. According to randomized controlled studies, in the absence of risk factors awareness phenomena occur in 1-2 per 1000 operations involving general anesthesia (0.1-0.2%) and are classified as occasionally occurring critical events. An astonishing twist occurred elicited by the recent data from the 5th National Audit Project from Great Britain (NAP5) published in the British Journal of Anaesthesia and in Anaesthesia. The NAP5 evaluated patient reports of accidental awareness during general anesthesia (AAGA) in a multicenter manner in more than 2.7 million cases and indicated incidences of awareness of only 1:19,600, a frequency 20 times less than previously reported. These results gave rise to some controversy. It seems likely that, due to the absence of structured interviews, the NAP5 data only demonstrated the tip of the iceberg and may have vastly underestimated the real incidence of intraoperative awareness. The present overview summarizes the current knowledge about awareness. Furthermore, it addresses the question whether the awareness problem has been overestimated by evidence-based criteria or underestimated by the results of the NAP5. The responsibility for sufficient anesthesia in the clinical routine requires knowledge of awareness risks and potential sequelae. A formal recommendation from the German Society of Anesthesia and Intensive Care Medicine (DGAI) concerning awareness is not yet available; however, the recognition of evidence-based strategies in the management of anesthesia may minimize the occurrence of awareness and its sequelae.

  10. E-resource knowledge bases and link resolvers: an assessment of the current products and emerging trends

    Directory of Open Access Journals (Sweden)

    Marshall Breeding

    2012-07-01

    Full Text Available This article summarizes the findings of a study on e-resource knowledge bases and OpenURL-based link resolvers sponsored by the National Library of Sweden. The project involved soliciting detailed information from each of the providers of the major products in this genre, reviewing product information available on the web and in published articles, and conducting a survey addressed to libraries using these products. The report identified and presented comparative information on a top tier of products that includes KnowledgeWorks and 360 Link from Serials Solutions; SFX Global KnowledgeBase and the SFX link resolver from Ex Libris; LinkSource and the EBSCO Integrated Knowledge Base from EBSCO and the WorldCat knowledge base from OCLC. A second tier included TOUResolver from TDNet, Gold Rush from the Colorado Alliance of Research Libraries and GODOT from Simon Fraser University. Innovative Interfaces, Inc offers the WebBridge link resolver but does not produce a knowledge base. The library survey revealed relatively narrow differences in the statistical results. Serial Solutions emerged as more favorable in most categories except for end-user functionality where Ex Libris received higher ratings. The Global Open Knowledgebase project (GOKb is noteworthy as a nascent community-based effort to produce a knowledge base. Key trends noted include less emphasis on knowledge bases and link resolvers as stand-alone products as they become integral components of comprehensive discovery and automation products.

  11. Content knowledge development in a chemistry teacher preparation program: A current potentials and challenges

    Science.gov (United States)

    Widhiyanti, Tuszie; Treagust, David F.; Mocerino, Mauro; Vishnumolakala, Venkat

    2017-08-01

    One of the essential facets in teacher education program is the development of the teachers' content knowledge and it has been suggested by many scholars that the study to analyse the process of content knowledge development in teacher education program is necessary. Regarding this, the aim of this research is to evaluate the existing program of developing pre-service chemistry teachers' content knowledge, especially in the topic about the particulate nature of matter. The curriculum of content knowledge development was analysed using the forms of the curriculum evaluation (Akker, 1998; Goodlad, Klein, and Tye (1979); Treagust, 1987). Within this framework, the curriculum was evaluated in several aspects including the vision and intention of the curriculum as mentioned in the curriculum documents (intended curriculum), the users' interpretation and perception about the curriculum (perceived curriculum), the actual process of curriculum implementation (implemented curriculum), and the outcomes of the curriculum (achieved curriculum). According to the framework used for this study, the research combined qualitative and quantitative methods of data collection and the interpretation including document analysis, classroom observation, interviews, and two-tier diagnostic test. Through this research we examined the coherence among those aspects. The results reveal that although the content knowledge development is explicitly intended in a curriculum, its implementation and lecturers' perceptions give influence in the results as appear in pre-service teachers' achievements. In general, this research provides basic information about the effectiveness of the program including the challenges and the potentials for a reconsideration of the program in the future.

  12. Pathways to fraction learning: Numerical abilities mediate the relation between early cognitive competencies and later fraction knowledge.

    Science.gov (United States)

    Ye, Ai; Resnick, Ilyse; Hansen, Nicole; Rodrigues, Jessica; Rinne, Luke; Jordan, Nancy C

    2016-12-01

    The current study investigated the mediating role of number-related skills in the developmental relationship between early cognitive competencies and later fraction knowledge using structural equation modeling. Fifth-grade numerical skills (i.e., whole number line estimation, non-symbolic proportional reasoning, multiplication, and long division skills) mapped onto two distinct factors: magnitude reasoning and calculation. Controlling for participants' (N=536) demographic characteristics, these two factors fully mediated relationships between third-grade general cognitive competencies (attentive behavior, verbal and nonverbal intellectual abilities, and working memory) and sixth-grade fraction knowledge (concepts and procedures combined). However, specific developmental pathways differed by type of fraction knowledge. Magnitude reasoning ability fully mediated paths from all four cognitive competencies to knowledge of fraction concepts, whereas calculation ability fully mediated paths from attentive behavior and verbal ability to knowledge of fraction procedures (all with medium to large effect sizes). These findings suggest that there are partly overlapping, yet distinct, developmental pathways from cognitive competencies to general fraction knowledge, fraction concepts, and fraction procedures.

  13. Mirizzi syndrome: History, current knowledge and proposal of a simplified classification

    Institute of Scientific and Technical Information of China (English)

    Marcelo A Beltrán

    2012-01-01

    Chronic complications of symptomatic gallstone disease,such as Mirizzi syndrome,are rare in Western developed countries with an incidence of less than 1% a year.The importance and implications of this condition are related to their associated and potentially serious surgical complications such as bile duct injury,and to its modern management when encountered during laparoscopic cholecystectomy.The pathophysiological process leading to the subtypes of Mirizzi syndrome has been explained by means of a pressure ulcer caused by an impacted gallstone at the gallbladder infundibulum,leading to an inflammatory response causing first external obstruction of the bile duct,and eventually eroding into the bile duct and evolving to a cholecystocholedochal or cholecystohepatic fistula.This article reviews the life of Pablo Luis Mirizzi,describes the earlier and later descriptions of Mirizzi syndrome,discusses the pathophysiological process leading to the development of these uncommon fistulas,reviews the current diagnostic modalities and surgical approaches and finally proposes a simplified classification for Mirizzi syndrome intended to standardize the reports on this condition and to eventually develop a consensual surgical approach to this unexpected and seriously dangerous condition.

  14. Anti-Tumor Necrosis Factor Alpha for Retinal Diseases: Current Knowledge and Future Concepts

    Directory of Open Access Journals (Sweden)

    Alireza Mirshahi

    2012-01-01

    Full Text Available Tumor necrosis factor alpha (TNF-α is a pro-inflammatory cytokine produced by macrophages and T-cells. It plays an important role both in inflammation and apoptosis. In the eye, TNF-α appears to have a role in the pathogenesis of inflammatory, edematous, neovascular and neurodegenerative disorders. Several TNF-blocking drugs have been developed and approved, and are in clinical use for inflammatory diseases such as rheumatoid arthritis, psoriasis and ankylosing spondylitis. TNF-α blockers are widely used in ophthalmology as an off-label alternative to "traditional" immunosuppressive and immune-modulatory treatments in noninfectious uveitis. Preliminary studies suggest a positive effect of intravenously administered TNF-α blockers, mainly infliximab, for treating refractory diabetic macular edema and neovascular age-related macular degeneration. Unfortunately, much of the current data raises considerable safety concerns for intravitreal use of TNF-α inhibitors, in particular, intraocular inflammatory responses have been reported after intravitreal injection of infliximab. Results of dose-finding studies and humanized antibody or antibody fragments (e.g. adalimumab are anticipated in the coming years; these will shed light on potential benefits and risks of local and systemic TNF-α blockers used for treatment of diseases of the retina and choroid.

  15. Anti-tumor necrosis factor alpha for retinal diseases: current knowledge and future concepts.

    Science.gov (United States)

    Mirshahi, Alireza; Hoehn, René; Lorenz, Katrin; Kramann, Christina; Baatz, Holger

    2012-01-01

    Tumor necrosis factor alpha (TNF-α) is a pro-inflammatory cytokine produced by macrophages and T-cells. It plays an important role both in inflammation and apoptosis. In the eye, TNF-α appears to have a role in the pathogenesis of inflammatory, edematous, neovascular and neurodegenerative disorders. Several TNF-blocking drugs have been developed and approved, and are in clinical use for inflammatory diseases such as rheumatoid arthritis, psoriasis and ankylosing spondylitis. TNF-α blockers are widely used in ophthalmology as an off-label alternative to "traditional" immunosuppressive and immune-modulatory treatments in noninfectious uveitis. Preliminary studies suggest a positive effect of intravenously administered TNF-α blockers, mainly infliximab, for treating refractory diabetic macular edema and neovascular age-related macular degeneration. Unfortunately, much of the current data raises considerable safety concerns for intravitreal use of TNF-α inhibitors, in particular, intraocular inflammatory responses have been reported after intravitreal injection of infliximab. Results of dose-finding studies and humanized antibody or antibody fragments (e.g. adalimumab) are anticipated in the coming years; these will shed light on potential benefits and risks of local and systemic TNF-α blockers used for treatment of diseases of the retina and choroid.

  16. Building Common Knowledge at the Boundaries between Professional Practices: Relational Agency and Relational Expertise in Systems of Distributed Expertise

    Science.gov (United States)

    Edwards, Anne

    2011-01-01

    The article develops an earlier account of relational agency ("IJER" 2005). Its starting point is a view of practices as knowledge-laden and emotionally freighted sites of purposeful and expert activity. Arguments therefore draw on cultural historical analyses of activities, practices and the institutions that shape them. Relational agency in…

  17. Knowledge Mobilization in Canadian Educational Research: Identifying Current Developments and Future Directions

    Directory of Open Access Journals (Sweden)

    Snezana Ratkovic

    2016-06-01

    Full Text Available In this special issue of Brock Education: Journal for Educational Research and Practice, we build on the knowledge mobilization (KMb discourses initiated by the Ontario Ministry of Education (MOE, Social Sciences and Humanities Research Council of Canada (SSHRC, Knowledge Network for Applied Education Research (KNAER, Canadian Society for the Study of Education (CSSE, and School District-University Research Exchange (SURE network. We feature five journal articles and a book review addressing the three main KMb questions: How to assess KMb efforts across educational systems?  To what extent do educators use research to inform their praxis? How to make KMb work?

  18. Developmental relations between vocabulary knowledge and reading comprehension: a latent change score modeling study.

    Science.gov (United States)

    Quinn, Jamie M; Wagner, Richard K; Petscher, Yaacov; Lopez, Danielle

    2015-01-01

    The present study followed a sample of first-grade (N = 316, Mage = 7.05 at first test) through fourth-grade students to evaluate dynamic developmental relations between vocabulary knowledge and reading comprehension. Using latent change score modeling, competing models were fit to the repeated measurements of vocabulary knowledge and reading comprehension to test for the presence of leading and lagging influences. Univariate models indicated growth in vocabulary knowledge, and reading comprehension was determined by two parts: constant yearly change and change proportional to the previous level of the variable. Bivariate models indicated previous levels of vocabulary knowledge acted as leading indicators of reading comprehension growth, but the reverse relation was not found. Implications for theories of developmental relations between vocabulary and reading comprehension are discussed.

  19. Employee Relations And Organizational Knowledge Sharing: An Application In Banking Sector

    Directory of Open Access Journals (Sweden)

    Gülşah KARAVARDAR

    2012-06-01

    Full Text Available In this study, employee relations and knowledge sharing relation’s analysing is aimed. According to this aim, a private bank’s branches’, which are located in Istanbul/ Anatolia side, employees are applied surveys. For determining employee relations a survey which was developed by S.Liao and study friends is used. For determining the knowledge sharing, the survey which was developed by R. K. Yeo and M. A. Youssef is used. The independent variable is employee relations which consists of working environment, conditions of respect, conditions of support, justice perception, relationship with superiors, self-satisfaction and self-learning. The dependent variable is knowledge sharing. Regression Analysis is used. According to regression analysis results, conditions of respect, conditions of support, justice perception and relationships with superiors have an effect on knowledge sharing.

  20. Knowledge of bisphosphonate-related osteonecrosis of the Jaws among Mexican dentists

    Science.gov (United States)

    Ibáñez-Mancera, Norma-Guadalupe; Aguilar-Rojas, Ana-Martha; Álvarez-Jardón, Ana-Pilar

    2017-01-01

    Background Bisphosphonate-related osteonecrosis is an infrequent but potentially serious complication. Its treatment remains complex, and in some cases can be mutilating. Prevention, a correct diagnosis and opportune management are crucial. Material and Methods A cross-sectional study was made, interviewing 410 dentists with the aim of assessing their knowledge of the subject. Results Practically all of the dental professionals (99.7%) were found to lack sufficient knowledge of the prevention, diagnosis and management of bisphosphonate-related osteonecrosis. Conclusions Actions including increased diffusion in the professional media and inclusion of the subject in training programs are needed in order to enhance the knowledge of bisphosphonate-related osteonecrosis among dentists and thus prevent complications in this group of patients. Key words:Knowledge, mexico, osteonecrosis, bisphosphonates. PMID:27918741

  1. Event-related potentials in response to violations of content and temporal event knowledge.

    Science.gov (United States)

    Drummer, Janna; van der Meer, Elke; Schaadt, Gesa

    2016-01-01

    Scripts that store knowledge of everyday events are fundamentally important for managing daily routines. Content event knowledge (i.e., knowledge about which events belong to a script) and temporal event knowledge (i.e., knowledge about the chronological order of events in a script) constitute qualitatively different forms of knowledge. However, there is limited information about each distinct process and the time course involved in accessing content and temporal event knowledge. Therefore, we analyzed event-related potentials (ERPs) in response to either correctly presented event sequences or event sequences that contained a content or temporal error. We found an N400, which was followed by a posteriorly distributed P600 in response to content errors in event sequences. By contrast, we did not find an N400 but an anteriorly distributed P600 in response to temporal errors in event sequences. Thus, the N400 seems to be elicited as a response to a general mismatch between an event and the established event model. We assume that the expectancy violation of content event knowledge, as indicated by the N400, induces the collapse of the established event model, a process indicated by the posterior P600. The expectancy violation of temporal event knowledge is assumed to induce an attempt to reorganize the event model in working memory, a process indicated by the frontal P600.

  2. Malassezia: Estado del conocimiento y perspectivas en su estudio Malassezia: Current knowledge and study perspectives

    Directory of Open Access Journals (Sweden)

    Gustavo E. Giusiano

    2006-03-01

    knowledge of the ecology and epidemiology of this genus. Noteworthy antifungal susceptibility variations have been observed in some species, although there is not a standard method for these yeasts. There are few data about their biochemical characteristics, and the enzymes they produce might be important virulence factors, favouring host tissue invasion. Malassezia has been recognised as a member of the normal human and animal skin. Its implication in pathologic processes, including skin diseases to systemic infections, is the main issue in current investigations in order to determine the real pathogenic role of these yeasts.

  3. Innate and adaptive immunity in the development of depression: An update on current knowledge and technological advances.

    Science.gov (United States)

    Haapakoski, Rita; Ebmeier, Klaus P; Alenius, Harri; Kivimäki, Mika

    2016-04-01

    The inflammation theory of depression, proposed over 20years ago, was influenced by early studies on T cell responses and since then has been a stimulus for numerous research projects aimed at understanding the relationship between immune function and depression. Observational studies have shown that indicators of immunity, especially C reactive protein and proinflammatory cytokines, such as interleukin 6, are associated with an increased risk of depressive disorders, although the evidence from randomized trials remains limited and only few studies have assessed the interplay between innate and adaptive immunity in depression. In this paper, we review current knowledge on the interactions between central and peripheral innate and adaptive immune molecules and the potential role of immune-related activation of microglia, inflammasomes and indoleamine-2,3-dioxygenase in the development of depressive symptoms. We highlight how combining basic immune methods with more advanced 'omics' technologies would help us to make progress in unravelling the complex associations between altered immune function and depressive disorders, in the identification of depression-specific biomarkers and in developing immunotherapeutic treatment strategies that take individual variability into account.

  4. Colloid-Facilitated Radionuclide Transport: Current State of Knowledge from a Nuclear Waste Repository Risk Assessment Perspective

    Energy Technology Data Exchange (ETDEWEB)

    Reimus, Paul William [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Zavarin, Mavrik [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Wang, Yifeng [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-01-25

    This report provides an overview of the current state of knowledge of colloid-facilitated radionuclide transport from a nuclear waste repository risk assessment perspective. It draws on work that has been conducted over the past 3 decades, although there is considerable emphasis given to work that has been performed over the past 3-5 years as part of the DOE Used Fuel Disposition Campaign. The timing of this report coincides with the completion of a 3-year DOE membership in the Colloids Formation and Migration (CFM) partnership, an international collaboration of scientists studying colloid-facilitated transport of radionuclides at both the laboratory and field-scales in a fractured crystalline granodiorite at the Grimsel Test Site in Switzerland. This Underground Research Laboratory has hosted the most extensive and carefully-controlled set of colloid-facilitated solute transport experiments that have ever been conducted in an in-situ setting, and a summary of the results to date from these efforts, as they relate to transport over long time and distance scales, is provided in Chapter 3 of this report.

  5. The status of tobacco use and knowledge, and attitudes relating to smoking among female students in a Bengbu medical school

    Institute of Scientific and Technical Information of China (English)

    Yulong Qi; Cuizhu Mei

    2009-01-01

    Objective: To learn the status of tobacco use, and the knowledge, attitudes, and behaviors among female students in Bengbu Medical College. Methods: In a cross-sectional survey, questionnaires were completed by 634 female students in the medical college in 2007,including the prevalence of current smoking, their knowledge of the effects of tobacco use on health, and attitudes towards the smoking behaviors of young women. Results: Only 6.9% of female medical students were former smokers, and 4.9% of them were current smokers. There was no significant difference in the current smoking rate among the students from each department surveyed. Female students from urban areas were more likely to be current or attempted smokers than those from rural areas. The proportion of the students who were aware of the health risks of smoking was less than 45%. The students from the Department of Nursing had more knowledge regarding the harmful health effects of smoking than those from the other departments. There was no significant difference in attitudes towards the smoking behaviors of young women among the students from each department. Compared with female students from rural areas, the female students from urban areas were significantly more likely to think that a young woman who smoked was cool, mature and charming. Conclusion: The smoking prevalence of the female students in Bengbu Medical College is high. They are not aware of the smoking related risks and have erroneous beliefs and perceptions about female smoking behaviors.

  6. A Case Analysis to Increase Awareness of Current USMC Knowledge Management (KM) Practices

    Science.gov (United States)

    2013-09-01

    communities” (p. 63; Virtanen, 2013, p. 119)  Capeda- Carrion (2006) states KM to be “the formalized, integrated approach of managing an enterprise’s...management and intellectual capital research,” Knowledge and Process Management,15(4): 235–246. doi:10.1002/kpm.314 Capeda- Carrion , G. (2006). Competitive

  7. Current Situation and Analysis of Geography Teachers' Active Learning Knowledge and Usage in Turkey

    Science.gov (United States)

    Tuna, Fikret

    2012-01-01

    In parallel to the developments in the approach to education, the secondary education geography curriculum in Turkey was renewed in 2005. This new programme encourages the use of active learning methods and techniques in the classroom by adopting the idea that students should construct and interpret knowledge by actively participating in the…

  8. Civic Education and Charter Schools: Current Knowledge and Future Research Issues

    Science.gov (United States)

    Chudowsky, Naomi; Chudowsky, Victor

    2012-01-01

    In recent years, as schools have shifted more attention to English language arts and mathematics, several groups have made a plea for renewed attention to civic education for all students. One such group is the Spencer Foundation, which promotes research to improve students' civics knowledge and skills and their dispositions for responsible…

  9. Current Knowledge and Training Needs of Certified Rehabilitation Counselors to Work Effectively with Veterans with Disabilities

    Science.gov (United States)

    Frain, Michael; Bishop, Malachy; Tansey, Timothy; Sanchez, Jennifer; Wijngaarde, Frank

    2013-01-01

    Veterans with disabilities have gained national attention in recent years because of the wars in Iraq and Afghanistan. This study examined certified rehabilitation counselors' (CRCs) knowledge and preparation for working with veterans with disabilities on their rehabilitation. Results indicate that CRCs report low levels of preparation in…

  10. Racial/ethnic differences in electronic cigarette knowledge, social norms, and risk perceptions among current and former smokers.

    Science.gov (United States)

    Webb Hooper, Monica; Kolar, Stephanie K

    2017-04-01

    Psychosocial factors that may affect electronic cigarette (e-cigarette) initiation or maintenance among racial/ethnic minorities are not well-understood. This study examined racial/ethnic differences in e-cigarette knowledge, risk perceptions, and social norms among current and former smokers. Individuals with a tobacco smoking history and an awareness of e-cigarettes (N=285) were recruited from the community from June to August 2014. Telephone-administered surveys assessed demographics, smoking status, and e-cigarette knowledge, risk perceptions, and normative beliefs. Analyses of covariance and multinomial logistic regression tested associations by race/ethnicity. Controlling for sociodemographics and smoking status, White participants scored significantly higher on e-cigarette knowledge, compared to both Hispanics and African Americans/Blacks. Knowledge was lower among African Americans/Blacks compared to Hispanics. Compared to both Whites and Hispanics, African American/Black participants held lower perceptions regarding e-cigarette health risks and were less likely to view e-cigarettes as addictive. Normative beliefs did not differ by race/ethnicity. In conclusion, e-cigarette knowledge, health risk perceptions, and perceived addictiveness differed by race/ethnicity. The variation in e-cigarette knowledge and beliefs among smokers and former smokers has implications for use, and potentially, dual use. Understanding these relationships in unrepresented populations can inform future research and practice. Copyright © 2017 Elsevier Ltd. All rights reserved.

  11. Public Relations in Contemporary India: Current Demands and Strategy.

    Science.gov (United States)

    Singh, Raveena

    2000-01-01

    Discusses India's new direction and the persistent and insistent demand for public relations. Explains the strategic plan of the professional body in running the gauntlet in this new milieu and the pertinaciousness and urgency of the challenges ahead for public relations. (SC)

  12. A review on current knowledge and future prospects of organohalogen contaminants (OHCs) in Asian birds

    Energy Technology Data Exchange (ETDEWEB)

    Abbasi, Naeem Akhtar [Environmental Biology and Ecotoxicology Laboratory, Department of Environmental Sciences, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad 45320 (Pakistan); Malik, Riffat Naseem, E-mail: r_n_malik2000@yahoo.co.uk [Environmental Biology and Ecotoxicology Laboratory, Department of Environmental Sciences, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad 45320 (Pakistan); Frantz, Adrien [Sorbonne Universités, UPMC Univ Paris 06, UPEC, Paris 7, CNRS, INRA, IRD, Institut d' Ecologie et des Sciences de l' Environnement de Paris, F-75005, Paris (France); Jaspers, Veerle Leontina Bernard [Environmental Toxicology, Department of Biology, Norwegian University of Science and Technology (NTNU), Trondheim (Norway)

    2016-01-15

    The release of harmful chemicals in the Asian environment has recently increased dramatically due to rising industrial and agricultural activities. About 60% of the global human population is currently living on the Asian continent and may thus be exposed to a large range of different chemicals. Different classes of organohalogen chemicals have indeed been reported in various environmental compartments from Asia including humans and wildlife, but this issue has received less attention in birds. In this article, we reviewed the available literature on levels of legacy persistent organic pollutants (POPs) and various flame retardants (FRs) in Asian avifauna to analyze the existing pool of knowledge as well as to identify the gaps that should be addressed in future research. Furthermore, we discussed the variation in levels of organohalogens based on differences in regions, trophic level, dietary sources and migratory behaviors of species including distribution patterns in different tissues of birds. Although the mass of published literature is very low and even absent in many important regions of Asia, we deduced from the reported studies that levels of almost all classes of organohalogens (OHCs) including FRs were highest in East Asian countries such as Japan, China and South Korea, except for HCHs that were found at maximum levels in birds of South India. Concentrations (ng/g LW) of different OHCs in Asian birds ranged between < LOD (limit of detection) to 14,000,000 for polychlorinated biphenyls (PCBs), < LOD to 790,000 for dichlorodiphenyltrichloroethane (DDTs), < LOD to 12,000 for hexachlorobenzene (HCB), < LOD to 29,000 for hexachlorocyclohexanes (HCHs), < LOD to 47,000 for chlordanes (CHLs) and < LOD to 4600 for total cyclodienes. Further, ranges (ng/g LW) of 1.1 to 150,000 for Co-PCBs; < LOD to 27 for polychlorinated dibenzo-p-dioxins (PCDDs); < LOD to 45 for polychlorinated dibenzofurans (PCDFs) and 0.02 to 73 for PCDD/DFs have been reported in Asian aves

  13. Current Sino-Latin American Relations and the Corresponding Policies

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    @@ Ⅰ. History of the Relationship and Its Current Situation. The Sino-Latin American relationship has a long-standing history that starts from the trade exchanges in the middle of the 16th century.From the 18th century to the early 19th century,hundreds and thousands of Chinese laborers were seized and sold by the western colonists to Latin America as "coolies" who made contribution to the local economic development there.

  14. HONGOS ENDÓFITOS TROPICALES: CONOCIMIENTO ACTUAL Y PERSPECTIVAS Tropical Endophytic Fungi: Current Knowledge and Perspectives

    Directory of Open Access Journals (Sweden)

    MIGUEL A GAMBOAGAITÁN

    Full Text Available Los organismos endófitos, particularmente los hongos, han recibido una creciente atención en los años recientes. Este grupo de microrganismos vive asintomáticamente dentro de tejidos vegetales sanos, y ha mostrado poseer un gran potencial económico en áreas como la agronomía y la medicina. También se han usado como grupo modelo para estudiar aspectos teóricos de la ecología de comunidades y de la interacción planta microorganismo. En la presente revisión se ha recopilado la literatura existente acerca de los hongos endófitos tropicales, y se analiza comparativamente con algunos trabajos de zonas templadas. Se discuten algunos de los aspectos más relevantes y promisorios en este sistema simbiótico y se hacen recomendaciones acerca de tópicos particulares hacia los que debe dirigirse la investigación en este campo.Endophytic microorganisms are symptomless inhabitants of plant tissues. This group is receiving a growing attention due to its potential in fields as varied as agronomy and medicine. Some more basic aspects of science, such as ecology of communities and plantmicrobe interactions have also been studied in this group. This review emphasizes on current literature about tropical endophytes and work in this theme is compared with those developed in temperate zones when appropriate. The most important ecological aspects of this system are discussed, and recommendations about the future directions of research in this field are done, especially those related to the use of endophytes as a model group in modern biology.

  15. Echinococcus granulosus sensu lato genotypes infecting humans--review of current knowledge.

    Science.gov (United States)

    Alvarez Rojas, Cristian A; Romig, Thomas; Lightowlers, Marshall W

    2014-01-01

    Genetic variability in the species group Echinococcus granulosus sensu lato is well recognised as affecting intermediate host susceptibility and other biological features of the parasites. Molecular methods have allowed discrimination of different genotypes (G1-10 and the 'lion strain'), some of which are now considered separate species. An accumulation of genotypic analyses undertaken on parasite isolates from human cases of cystic echinococcosis provides the basis upon which an assessment is made here of the relative contribution of the different genotypes to human disease. The allocation of samples to G-numbers becomes increasingly difficult, because much more variability than previously recognised exists in the genotypic clusters G1-3 (=E. granulosus sensu stricto) and G6-10 (Echinococcus canadensis). To accommodate the heterogeneous criteria used for genotyping in the literature, we restrict ourselves to differentiate between E. granulosus sensu stricto (G1-3), Echinococcus equinus (G4), Echinococcus ortleppi (G5) and E. canadensis (G6-7, G8, G10). The genotype G1 is responsible for the great majority of human cystic echinococcosis worldwide (88.44%), has the most cosmopolitan distribution and is often associated with transmission via sheep as intermediate hosts. The closely related genotypes G6 and G7 cause a significant number of human infections (11.07%). The genotype G6 was found to be responsible for 7.34% of infections worldwide. This strain is known from Africa and Asia, where it is transmitted mainly by camels (and goats), and South America, where it appears to be mainly transmitted by goats. The G7 genotype has been responsible for 3.73% of human cases of cystic echinococcosis in eastern European countries, where the parasite is transmitted by pigs. Some of the samples (11) could not be identified with a single specific genotype belonging to E. canadensis (G6/10). Rare cases of human cystic echinococcosis have been identified as having been caused by

  16. Marine biodiversity in South Africa: an evaluation of current states of knowledge.

    Directory of Open Access Journals (Sweden)

    Charles L Griffiths

    Full Text Available Continental South Africa has a coastline of some 3,650 km and an Exclusive Economic Zone (EEZ of just over 1 million km(2. Waters in the EEZ extend to a depth of 5,700 m, with more than 65% deeper than 2,000 m. Despite its status as a developing nation, South Africa has a relatively strong history of marine taxonomic research and maintains comprehensive and well-curated museum collections totaling over 291,000 records. Over 3 million locality records from more than 23,000 species have been lodged in the regional AfrOBIS (African Ocean Biogeographic Information System data center (which stores data from a wider African region. A large number of regional guides to the marine fauna and flora are also available and are listed. The currently recorded marine biota of South Africa numbers at least 12,914 species, although many taxa, particularly those of small body size, remain poorly documented. The coastal zone is relatively well sampled with some 2,500 samples of benthic invertebrate communities have been taken by grab, dredge, or trawl. Almost none of these samples, however, were collected after 1980, and over 99% of existing samples are from depths shallower than 1,000 m--indeed 83% are from less than 100 m. The abyssal zone thus remains almost completely unexplored. South Africa has a fairly large industrial fishing industry, of which the largest fisheries are the pelagic (pilchard and anchovy and demersal (hake sectors, both focused on the west and south coasts. The east coast has fewer, smaller commercial fisheries, but a high coastal population density, resulting in intense exploitation of inshore resources by recreational and subsistence fishers, and this has resulted in the overexploitation of many coastal fish and invertebrate stocks. South Africa has a small aquaculture industry rearing mussels, oysters, prawns, and abalone-the latter two in land-based facilities. Compared with many other developing countries, South Africa has a well

  17. Assessment of parental knowledge and attitudes toward pediatric sports-related concussions.

    Science.gov (United States)

    Lin, Ann C; Salzman, Garrett A; Bachman, Shelby L; Burke, Rita V; Zaslow, Tracy; Piasek, Carolina Z; Edison, Bianca R; Hamilton, Anita; Upperman, Jeffrey S

    2015-03-01

    Parents of young athletes play a major role in the identification and management of sports-related concussions. However, they are often unaware of the consequences of concussions and recommended management techniques. This study quantitatively assessed parental understanding of concussions to identify specific populations in need of additional education. We predicted that parents with increased education and prior sports- and concussion-related experience would have more knowledge and safer attitudes toward concussions. Cross-sectional survey. Level 5. Participants were parents of children brought to a pediatric hospital and 4 satellite clinics for evaluation of orthopaedic injuries. Participants completed a validated questionnaire that assessed knowledge of concussion symptoms, attitudes regarding diagnosis and return-to-play guidelines, and previous sports- and concussion-related experience. Over 8 months, 214 parents completed surveys. Participants scored an average of 18.4 (possible, 0-25) on the Concussion Knowledge Index and 63.1 (possible, 15-75) on the Concussion Attitude Index. Attitudes were safest among white women, and knowledge increased with income and education levels. Previous sports experience did not affect knowledge or attitudes, but parents who reported experiencing an undiagnosed concussion had significantly better concussion knowledge than those who did not. Parents with low income and education levels may benefit from additional concussion-related education. There exist many opportunities for improvement in parental knowledge and attitudes about pediatric sports-related concussions. Ongoing efforts to understand parental knowledge of concussions will inform the development of a strategic and tailored approach to the prevention and management of pediatric concussions.

  18. Etiology and epidemiology of Pythium root rot in hydroponic crops: current knowledge and perspectives

    Directory of Open Access Journals (Sweden)

    John Clifford Sutton

    2006-09-01

    knowledge and understanding of the etiology and epidemiology of root rot, and its effects on the physiology of the whole plant, are discussed in relation to new research directions and development of better practices to manage the disease in hydroponic crops. Focus is on methods and technologies for tracking Pythium and root rot, and on developing, integrating, and optimizing treatments to suppress the pathogen in the root zone and progress of root rot.A etiologia e a epidemiologia da podridão radicular causada por Pythium spp. em cultivo hidropônico são revisadas com ênfase em conhecimentos e conceitos considerados importantes para o manejo de doenças em estufas comerciais. A podridão radicular causada por Pythium continuamente ameaça a produtividade de diversas culturas em sistemas hidropônicos, incluindo pepino, tomate, pimentão, espinafre, alface, capuchinha, rúcula, rosa, e crisântemo. Os principais agentes causais incluem Pythium aphanidermatum, Pythium dissotocum, espécies de Pythium do grupo F e Pythium ultimum var. ultimum. São apresentadas e discutidas as principais fontes do inóculo primário de Pythium spp. em sistemas hidropônicos, os processos de infecção e colonização de raízes pelos patógenos, o desenvolvimento de sintomas, a produção de inóculo em raízes, e a dispersão do inóculo na solução nutritiva. Descobertas recentes da existência de um elicitor produzido especificamente por P. aphanidermatum que pode provocar a necrose (descoloração das raízes infectadas e a transição da infecção da fase biotrofica para necrotrofica são consideradas. Efeitos de fatores ligados ao hospedeiro (susceptibilidade à doença, estádio fenológico, exsudatos radiculares, compostos fenólicos, ao ambiente radicular (meio de enraizamento, concentrações de oxigênio dissolvido e compostos fenólicos na solução nutritiva, comunidades microbianas e temperatura e as interferências humanas (práticas de cultivo e medidas de controle sobre

  19. Geothermal projects funded under the NER 300 programme - current state of development and knowledge gained

    Science.gov (United States)

    Uihlein, Andreas; Salto Saura, Lourdes; Sigfusson, Bergur; Lichtenvort, Kerstin; Gagliardi, Filippo

    2015-04-01

    Introduction The NER 300 programme, managed by the European Commission is one of the largest funding programmes for innovative low-carbon energy demonstration projects. NER 300 is so called because it is funded from the sale of 300 million emission allowances from the new entrants' reserve (NER) set up for the third phase of the EU emissions trading system (ETS). The programme aims to successfully demonstrate environmentally safe carbon capture and storage (CCS) and innovative renewable energy (RES) technologies on a commercial scale with a view to scaling up production of low-carbon technologies in the EU. Consequently, it supports a wide range of CCS and RES technologies (bioenergy, concentrated solar power, photovoltaics, geothermal, wind, ocean, hydropower, and smart grids). Funded projects and the role of geothermal projects for the programme In total, about EUR 2.1 billion have been awarded to 39 projects through the programme's 2 calls for proposals (the first awarded in December 2012, the second in July 2014). The programme has awarded around 70 mEUR funding to 3 geothermal projects in Hungary, Croatia and France (see Annex). The Hungarian geothermal project awarded funding under the first call will enter into operation at the end of 2015 and the rest are expected to start in 2016 (HR) and in 2018 (FR), respectively. Knowledge Sharing Knowledge sharing requirements are built into the legal basis of the programme as a critical tool to lower risks in bridging the transition to large-scale production of innovative renewable energy and CCS deployment. Projects have to submit annually to the European Commission relevant knowledge gained during that year in the implementation of their project. The relevant knowledge is aggregated and disseminated by the European Commission to industry, research, government, NGO and other interest groups and associations in order to provide a better understanding of the practical challenges that arise in the important step of

  20. Geothermal projects funded under the NER 300 programme - current state of development and knowledge gained

    Science.gov (United States)

    Shortall, Ruth; Uihlein, Andreas

    2017-04-01

    Introduction The NER 300 programme, managed by the European Commission is one of the largest funding programmes for innovative low-carbon energy demonstration projects. NER 300 is so called because it is funded from the sale of 300 million emission allowances from the new entrants' reserve (NER) set up for the third phase of the EU emissions trading system (ETS). The programme aims to successfully demonstrate environmentally safe carbon capture and storage (CCS) and innovative renewable energy (RES) technologies on a commercial scale with a view to scaling up production of low-carbon technologies in the EU. Consequently, it supports a wide range of CCS and RES technologies (bioenergy, concentrated solar power, photovoltaics, geothermal, wind, ocean, hydropower, and smart grids). Funded projects and the role of geothermal projects for the programme In total, about EUR 2.1 billion have been awarded through the programme's 2 calls for proposals (the first awarded in December 2012, the second in July 2014). The programme has awarded around EUR 70 million funding to 3 geothermal projects in Hungary, Croatia and France. The Croatian geothermal project will enter into operation during 2017 the Hungarian in 2018, and the French in 2020. Knowledge Sharing Knowledge sharing requirements are built into the legal basis of the programme as a critical tool to lower risks in bridging the transition to large-scale production of innovative renewable energy and CCS deployment. Projects have to submit annually to the European Commission relevant knowledge gained during that year in the implementation of their project. The relevant knowledge is aggregated and disseminated by the European Commission to industry, research, government, NGO and other interest groups and associations in order to provide a better understanding of the practical challenges that arise in the important step of scaling up technologies and operating them at commercial scale. The knowledge sharing of the NER 300

  1. [Epidemiologic knowledge and current situation of Chagas disease in the state of Jalisco, Mexico].

    Science.gov (United States)

    Lozano-Kasten, Felipe; Magallón-Gastélum, Ezequiel; Soto-Gutiérrez, Margarita; Kasten-Monges, Marina; Bosseno, Marie-France; Brenière, Simone Frédérique

    2008-01-01

    Chagas disease in the state of Jalisco, Mexico was described for the first time in 1967; however, knowledge on the disease remains in a slow process. Between 1967 and 2006, the disease was described in its acute and chronic forms. The vector species have been identified, and the parasite Trypanosoma cruzi has been isolated and genetically characterized. Also, the magnitude of the infection in humans has been determined through serological studies of different populations as well as of blood donors. The up-to-dateness of knowledge of the disease in the state of Jalisco, unveils a necessity of increased research on the epidemiology of Chagas disease as well as on clinical studies to assess the health of individuals and the populations.

  2. Preface: conservation of european ponds-current knowledge and future needs

    OpenAIRE

    Miracle, Rosa; Oertli, Beat; Céréghino, Régis; Hull, Andrew P.

    2010-01-01

    Ponds are common elements of the landscape with an important role in the global processes of biosphere and biodiversity preservation. Recent research indicates that ecological characteristics of ponds are different from other inland water systems, but scientific knowledge is still insufficient and poor compared to lakes and rivers. Therefore, whilst indicators and conservation tools have been developed for most aquatic systems, there is also a gap between existing basic information on pond ec...

  3. Mycobacterium bovis infection in the lion (Panthera leo): Current knowledge, conundrums and research challenges.

    Science.gov (United States)

    Viljoen, Ignatius M; van Helden, Paul D; Millar, Robert P

    2015-06-12

    Mycobacterium bovis has global public-health and socio-economic significance and can infect a wide range of species including the lion (Panthera leo) resulting in tuberculosis. Lions are classified as vulnerable under the IUCN Red List of Threatened Species and have experienced a 30% population decline in the past two decades. However, no attempt has been made to collate and critically evaluate the available knowledge of M. bovis infections in lions and potential effects on population. In this review we set out to redress this. Arguments suggesting that ingestion of infected prey animals are the main route of infection for lions have not been scientifically proven and research is needed into other possible sources and routes of infection. The paucity of knowledge on host susceptibility, transmission directions and therefore host status, manifestation of pathology, and epidemiology of the disease in lions also needs to be addressed. Advances have been made in diagnosing the presence of M. bovis in lions. However, these diagnostic tests are unable to differentiate between exposure, presence of infection, or stage of disease. Furthermore, there are contradictory reports on the effects of M. bovis on lion populations with more data needed on disease dynamics versus the lion population's reproductive dynamics. Knowledge on disease effects on the lion reproduction and how additional stressors such as drought or co-morbidities may interact with tuberculosis is also lacking. Filling these knowledge gaps will contribute to the understanding of mycobacterial infections and disease in captive and wild lions and assist in lion conservation endeavours. Copyright © 2015 Elsevier B.V. All rights reserved.

  4. A survey of current knowledge on sexually transmitted diseases and sexual behaviour in Italian adolescents

    OpenAIRE

    Francesco Drago; Giulia Ciccarese; Francesca Zangrillo; Giulia Gasparini; Ludovica Cogorno; Silvia Riva; Sanja Javor; Emanuele Cozzani; Francesco Broccolo; Susanna Esposito; Aurora Parodi

    2016-01-01

    Worldwide, 500 million people a year acquire a sexually transmitted disease (STD). Adolescents, accounting for 25% of the sexually active population, are the most affected. To analyze sexual behavior among Italian adolescents and their knowledge of STDs, with the goal of preventing their transmission, a questionnaire was administered to 2867 secondary school students (1271 males and 1596 females) aged 14–21 years. For the study, 1492 students were interviewed in Genoa (Northern Italy) and 137...

  5. How Do Clinicians Learn About Knowledge Translation? An Investigation of Current Web-Based Learning Opportunities

    OpenAIRE

    Damarell, Raechel A; Tieman, Jennifer J

    2017-01-01

    Background Clinicians are important stakeholders in the translation of well-designed research evidence into clinical practice for optimal patient care. However, the application of knowledge translation (KT) theories and processes may present conceptual and practical challenges for clinicians. Online learning platforms are an effective means of delivering KT education, providing an interactive, time-efficient, and affordable alternative to face-to-face education programs. Objective This study ...

  6. The current status of knowledge of herbal medicine and medicinal plants in Fiche, Ethiopia

    OpenAIRE

    d’Avigdor, Elizabeth; Wohlmuth, Hans; Asfaw, Zemede; Awas, Tesfaye

    2014-01-01

    Background A majority of Ethiopians rely on traditional medicine as their primary form of health care, yet they are in danger of losing both their knowledge and the plants they have used as medicines for millennia. This study, conducted in the rural town of Fiche in Ethiopia, was undertaken with the support of Southern Cross University (SCU) Australia, Addis Ababa University (AAU) Ethiopia, and the Ethiopian Institute of Biodiversity (EIB), Ethiopia. The aim of this study, which included an e...

  7. Fascia--Current knowledge and future directions in physiatry: narrative review.

    Science.gov (United States)

    Kwong, Evan H; Findley, Thomas W

    2014-01-01

    Fascia can be considered part of the connective tissues that permeates the human body. However, in medical training its definition is not clear, and even among specialists its role is not completely understood. Physiatrists have a unique opportunity to add to the growing scientific and clinical knowledge about fascia, particularly about how this connective tissue network may apply clinically to musculoskeletal disorders. In this narrative review, the structure and function of fascia is discussed from the perspective of physiatry.

  8. Current status of research and related activities in NAA application

    Energy Technology Data Exchange (ETDEWEB)

    Ab. Khalik bin Haji Wood [Malaysia Institute for Nuclear Technology Research, Bangi, Selangor (Malaysia)

    1999-10-01

    Current activities of Analytical Chemistry Group of MINT (Malaysia Institute for Nuclear Technology Research) laboratory for elemental analysis of trace amounts in environmental samples such as air particulate matter (on air filter), soils/sediments, water, flora/fauna, oil sludge/waste sludge, and tailing/blasting slag and others, utilizing particularly NAA (Neutron Activation Analysis) method are reviewed. The laboratory participates in the IAEA-organized Interlaboratory Comparison Studies to ensure the analytical system. Other activities include analytical chemistry services with ICP-mass spectrometry and GC/GCMS to compliment the NAA and, moreover, air and marine pollution studies with participation in the UNDP/RCA/IAEA project. (S. Ohno)

  9. A study of masturbatory knowledge and attitudes and related factors among Taiwan adolescents.

    Science.gov (United States)

    Wang, Rung-Jy; Huang, Yu; Lin, Yen-Chin

    2007-09-01

    The main purpose of this study was to investigate the relationship between masturbatory knowledge and masturbatory attitudes among Taiwan adolescents. This study was based on a structured questionnaire survey that used the Adolescent Masturbatory Knowledge Inventory (AMKI) and the Adolescent Negative Attitude toward Masturbation Inventory (ANAMI). Subjects were recruited from the third grade of high school and vocational school students aged 17-18 living in Kaohsiung (southern Taiwan) using stratified and cluster sampling approaches. Seven hundred and eighty questionnaires were sent out, with a 96.8% response rate. A total of 95.3% of male subjects and 30.3% of female subjects reported having masturbation experience. Masturbatory knowledge was significantly related to the variables "school system", "frequency of viewing pornographic media", "status of being sexually active", and "conversation about sex with friends". Masturbatory attitudes were significantly associated with the same variables as well as with gender and masturbatory behavior. Masturbatory attitudes were positively correlated with masturbatory knowledge. The school system explained 15.4% of masturbatory knowledge variance. Masturbatory knowledge, masturbatory behavior, frequency of viewing pornographic media and status of being sexually active explained 39.5% of masturbatory attitude variance. In conclusion, adolescents in Taiwan hold positive attitudes toward masturbation and reported having insufficient knowledge regarding masturbation. Results can assist school staffs and parents to gain a deeper understanding of adolescents' knowledge about and attitudes toward masturbation.

  10. Current Challenges for the Knowledge Society. Toward Digital Inclusion in Latin America

    Directory of Open Access Journals (Sweden)

    Migdalia Pineda

    2009-08-01

    Full Text Available This work makes reference to the subject of the present challenges of the society of the knowledge as far as the profit of the digital inclusion, mainly in Latin America, for which one stops in analyzing the incidence of the technologies of the information and the communication in the construction of the knowledge in the contemporary societies. Also, one approaches the problem of the social innovation in the production of popular contents and knowledge, and of the social inclusion like condition indispensable for an inclusion sustained in the social appropriation of the TIC. Methodologically, the investigation when being cradle in an ampler theoretical study, at the moment in course, titleholder: “Society of the Information, post modernity and culture of masses”, is of documentary and bibliographical character, so that it makes a conceptual analysis of the subjects boarded. Finally some actions and recommendations for the digital inclusion set out, by means of the creation of social networks, the sectors and worked against communities more in the zone.

  11. Causes of work-related stress and individual strategies in knowledge work

    DEFF Research Database (Denmark)

    Ipsen, Christine; Jensen, Per Langaa

    – it can be both exciting and stressful. With regard to causes, it is evident that the strains of knowledge work are often caused by the organization and management of the knowledge worker. Autonomy and individualized responsibility causes both a formal and informal transfer of responsibility...... to the individual for his or her working life. Self-managed knowledge workers thus experience that they stand alone when it comes to work-related problems and stress. The stress intervention applied is characteristically short-term and focused on the individual. The individual perspective consequently affects...

  12. Organ preconditioning: the past, current status, and related lung studies

    Institute of Scientific and Technical Information of China (English)

    LUH Shi-ping; YANG Pan-chyr

    2006-01-01

    Preconditioning (PC) has emerged as a powerful method for experimentally and clinically attenuating various types of organ injuries. In this paper related clinical and basic research issues on organ preconditioning issues were systemically reviewed.Since lung injuries, including ischemia-reperfusion and others, play important roles in many clinical results, including thromboembolism, trauma, thermal injury, hypovolemic and endotoxin shock, reimplantation response after organ transplantation, and many respiratory diseases in critical care. It is of interest to uncover methods, including the PCs, to protect the lung from the above injuries. However, related studies on pulmonary PC are relatively rare and still being developed, so we will review previous literature on experimental and clinical studies on pulmonary PC in the following paragraphs.

  13. Translation of overlay models of student knowledge for relative domains based on domain ontology mapping

    DEFF Research Database (Denmark)

    Sosnovsky, Sergey; Dolog, Peter; Henze, Nicola;

    2007-01-01

    argue that the implementation of underlying knowledge models in a sharable format, as domain ontologies - along with application of automatic ontology mapping techniques for model alignment - can help to overcome the "new-user" problem and will greatly widen opportunities for student model translation....... Moreover, it then becomes possible for systems from relevant domains to rely on knowledge transfer and reuse those portions of the student models that are related to overlapping concepts....

  14. Parents' attitudes, knowledge and behaviours relating to safe child occupant travel.

    Science.gov (United States)

    Koppel, Sjaan; Muir, Carlyn; Budd, Laurie; Devlin, Anna; Oxley, Jennie; Charlton, Judith L; Newstead, Stuart

    2013-03-01

    This study investigated parents' attitudes, knowledge and behaviours relating to safe child occupant travel following new Australian legislation regarding child restraint system (CRS) and motor vehicle restraint use for children aged 7 years and under. A questionnaire exploring attitudes, knowledge and behaviours regarding general road safety, as well as safe child occupant travel, was completed by 272 participants with at least one child aged between 3 and 10 years residing in the Australian state of Victoria. Responses to the questionnaire revealed that participants' attitudes, knowledge and behaviours towards road safety in general were fairly positive, with most participants reporting that they restrict their alcohol consumption or do not drink at all while driving (87%), drive at or below the speed limit (85%) and 'always' wear their seatbelts (98%). However, more than half of the participants reported engaging in distracting behaviours 'sometimes' or 'often' (54%) and a small proportion of participants indicated that they 'sometimes' engaged in aggressive driving (14%). Regarding their attitudes, knowledge and behaviours relating to safe child occupant travel, most participants reported that they 'always' restrain their children (99%). However, there was a surprisingly high proportion of participants who did not know the appropriate age thresholds' to transition their child from a booster seat to an adult seatbelt (53%) or the age for which it is appropriate for their child to sit in the front passenger seat of the vehicle (20%). Logistic regression analyses revealed that parents' knowledge regarding safe child occupant travel was significantly related to their attitudes, knowledge and behaviours towards road safety in general, such as drinking habits while driving and CRS safety knowledge. Based on the findings of this study, a number of recommendations are made for strategies to enhance parents' attitudes, knowledge and behaviours relating to safe child

  15. Knowledge and Attitude Regarding Organ Donation among Relatives of Patients Referred to the Emergency Department

    Directory of Open Access Journals (Sweden)

    Mahboob Pouraghaei

    2015-01-01

    Full Text Available Introduction: Organ donation is one of the surviving procedures which can increase the life expectancy of end-stage patients. Inappropriate beliefs and attitude of individuals to organ donation, their poor knowledge, and the socio-economic level are one of the most important barriers for organ donation. Therefore, here knowledge and attitude levels among relatives of trauma patients regarding organ donation were evaluated. Methods: This cross-sectional study was done on relatives of trauma patients referred to the emergency department of Sina Hospital, Tabriz, Iran, through 2013 to 2014. The questionnaire included parts of demographic data and socio-economic situations as well as status of knowledge and attitude regarding organ donation. A score between 0-7 was belonged to each person based on his/her level of knowledge. Attitude level had a score between 0-12. Chi- square, Fisher, and Mann–Whitney U test were performed to assess the relation between demographic variables and the level of knowledge and attitude. P<0.05 was considered as a significant level. Results: 79 persons (57.1% male with the mean age of 31.3±11.3 years were evaluated. 57 (73.1% of subjects agreed with organ transplant. The main causes of disagreement among relatives regarding organ donation were dissatisfaction of the donor's relatives (25% and religious issues (15%. 49 (62.02% studied people had inappropriate attitude and 27 (34.2% ones had good knowledge. male gender (OR=5.87; 95%CI: 3.32-8.42; p=0.001 and self-employed job (OR=7.78; 95%CI: 4.64-10.92; p=0.001 are independent factors associated with poor knowledge about organ donation. Self-employed job (OR=3.86; 95%CI: 1.41-6.11; p=0.009 and poor knowledge (OR=15.3; 95%CI: 9.03-21.57; p<0.001 were related to inappropriate attitude toward organ donation. Conclusion: The present study showed that 73.1% of participants agreed with organ donation. The major causes of disagreements were dissatisfaction of other relatives

  16. Sport Physiology Research and Governing Gender in Sport--A Power-Knowledge Relation?

    Science.gov (United States)

    Larsson, Hakan

    2013-01-01

    This article sets out to show how physiological knowledge about sex/gender relates to power issues within sport. The sport physiology research at the Swedish School of Sport and Health Sciences (Swedish acronym: GIH) during the twentieth century is analysed in relation to the political rationality concerning gender at GIH and within the Swedish…

  17. Elementary Physical Education Teachers' Content Knowledge of Physical Activity and Health-Related Fitness

    Science.gov (United States)

    Santiago, Jose A.; Disch, James G.; Morales, Julio

    2012-01-01

    The purpose of this study was to examine elementary physical education teachers' content knowledge of physical activity and health-related fitness. Sixty-four female and 24 male teachers completed the Appropriate Physical Activity and Health-Related Fitness test. Descriptive statistics results indicated that the mean percentage score for the test…

  18. Belief, Knowledge and Understanding: How to Deal with the Relations between Different Cultural Perspectives in Classrooms

    Science.gov (United States)

    Moreira-dos-Santos, Frederik; El-Hani, Charbel N.

    2017-01-01

    This article discusses how to deal with the relations between different cultural perspectives in classrooms, based on a proposal for considering understanding and knowledge as goals of science education, inspired by Dewey's naturalistic humanism. It thus combines educational and philosophical interests. In educational terms, our concerns relate to…

  19. Examining Relations between Mathematics Teachers' Instructional Vision and Knowledge and Change in Practice

    Science.gov (United States)

    Munter, Charles; Correnti, Richard

    2017-01-01

    This article provides a longitudinal examination of how changes in more than 200 middle-grades mathematics teachers' instructional practices related to their (a) mathematical knowledge for teaching (MKT) and (b) instructional vision. Results of this multilevel regression analysis suggest that MKT and instructional vision are related to instruction…

  20. Sport Physiology Research and Governing Gender in Sport--A Power-Knowledge Relation?

    Science.gov (United States)

    Larsson, Hakan

    2013-01-01

    This article sets out to show how physiological knowledge about sex/gender relates to power issues within sport. The sport physiology research at the Swedish School of Sport and Health Sciences (Swedish acronym: GIH) during the twentieth century is analysed in relation to the political rationality concerning gender at GIH and within the Swedish…

  1. Elementary Physical Education Teachers' Content Knowledge of Physical Activity and Health-Related Fitness

    Science.gov (United States)

    Santiago, Jose A.; Disch, James G.; Morales, Julio

    2012-01-01

    The purpose of this study was to examine elementary physical education teachers' content knowledge of physical activity and health-related fitness. Sixty-four female and 24 male teachers completed the Appropriate Physical Activity and Health-Related Fitness test. Descriptive statistics results indicated that the mean percentage score for the test…

  2. International Inventory of Current Mexico-Related Research. Volume 4.

    Science.gov (United States)

    Montoya, Ricardo Anzaldua, Ed.; And Others

    The fourth annual research inventory describes 728 Mexican-related research projects being conducted in 1984 or to begin in 1985 in 14 countries. Data come from questionnaires sent during 1984 to more than 1,800 individual researchers and 650 institutions around the world. Each project description provides names and addresses of principal and…

  3. A Review on Current Status of Stability and Knowledge on Liquid Electrolyte-Based Dye-Sensitized Solar Cells

    Directory of Open Access Journals (Sweden)

    Frédéric Sauvage

    2014-01-01

    Full Text Available The purpose of this review is to gather the current background in materials development and provide the reader with an accurate image of today’s knowledge regarding the stability of dye-sensitized solar cells. This contribution highlights the literature from the 1970s to the present day on nanostructured TiO2, dye, Pt counter electrode, and liquid electrolyte for which this review is focused on.

  4. Systematic review of the current status of programs and general knowledge of diagnosis and management of retinoblastoma

    Directory of Open Access Journals (Sweden)

    Marco A. Ramírez-Ortiz

    2017-01-01

    Conclusions: There is an immediate need in Mexico to expand primary care providers’ knowledge of Rb and to expand and upgrade current Rb programs to meet the needs of the population adequately. Diagnosis and care of Rb patients in Mexico can also be improved by the establishment of a national Rb registry and a national early detection program, and by increased use of the national treatment protocol.

  5. Asthma-related emergency department use: current perspectives.

    Science.gov (United States)

    Johnson, Laurie H; Chambers, Patricia; Dexheimer, Judith W

    2016-01-01

    Asthma is one of the most common chronic pediatric diseases. Patients with asthma often present to the emergency department for treatment for acute exacerbations. These patients may not have a primary care physician or primary care home, and thus are seeking care in the emergency department. Asthma care in the emergency department is multifaceted to treat asthma patients appropriately and provide quality care. National and international guidelines exist to help drive clinical care. Electronic and paper-based tools exist for both physicians and patients to help improve emergency, home, and preventive care. Treatment of patients with asthma should include the acute exacerbation, long-term management of controller medications, and controlling triggers in the home environment. We will address the current state of asthma research in emergency medicine in the US, and discuss some of the resources being used to help provide a medical home and improve care for patients who suffer from acute asthma exacerbations.

  6. Knowledge and Attitude Regarding Organ Donation among Relatives of Patients Referred to the Emergency Department.

    Science.gov (United States)

    Pouraghaei, Mahboob; Tagizadieh, Mohammad; Tagizadieh, Ali; Moharamzadeh, Payman; Esfahanian, Samaneh; Shahsavari Nia, Kavous

    2015-01-01

    Organ donation is one of the surviving procedures, which can increase the life expectancy of end-stage patients. Inappropriate beliefs and attitude of individuals to organ donation, their poor knowledge, and the socio-economic level are one of the most important barriers for organ donation. Therefore, here knowledge and attitude levels among relatives of trauma patients regarding organ donation were evaluated. This cross-sectional study was done on relatives of trauma patients referred to the emergency department of Sina Hospital, Tabriz, Iran, through 2013 to 2014. The questionnaire included parts of demographic data and socio-economic situations as well as status of knowledge and attitude regarding organ donation. A score between 0-7 was belonged to each person based on his/her level of knowledge. Attitude level had a score between 0-12. Chi- square, Fisher, and Mann-Whitney U test were performed to assess the relation between demographic variables and the level of knowledge and attitude. Porgan transplant. The main causes of disagreement among relatives regarding organ donation were dissatisfaction of the donor's relatives (25%) and religious issues (15%). 49 (62.02%) studied people had inappropriate attitude and 27 (34.2%) ones had good knowledge. male gender (OR=5.87; 95%CI: 3.32-8.42; p=0.001) and self-employed job (OR=7.78; 95%CI: 4.64-10.92; p=0.001) are independent factors associated with poor knowledge about organ donation. Self-employed job (OR=3.86; 95%CI: 1.41-6.11; p=0.009) and poor knowledge (OR=15.3; 95%CI: 9.03-21.57; porgan donation. The present study showed that 73.1% of participants agreed with organ donation. The major causes of disagreements were dissatisfaction of other relatives and religious beliefs. 62.0% of the studied people had positive view regarding organ donation and 34.2% of them well informed about. The most important causative factors for poor knowledge in this context were male gender and self-employed occupation. In addition

  7. Current Overview of Allergens of Plant Pathogenesis Related Protein Families

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    Mau Sinha

    2014-01-01

    Full Text Available Pathogenesis related (PR proteins are one of the major sources of plant derived allergens. These proteins are induced by the plants as a defense response system in stress conditions like microbial and insect infections, wounding, exposure to harsh chemicals, and atmospheric conditions. However, some plant tissues that are more exposed to environmental conditions like UV irradiation and insect or fungal attacks express these proteins constitutively. These proteins are mostly resistant to proteases and most of them show considerable stability at low pH. Many of these plant pathogenesis related proteins are found to act as food allergens, latex allergens, and pollen allergens. Proteins having similar amino acid sequences among the members of PR proteins may be responsible for cross-reactivity among allergens from diverse plants. This review analyzes the different pathogenesis related protein families that have been reported as allergens. Proteins of these families have been characterized in regard to their biological functions, amino acid sequence, and cross-reactivity. The three-dimensional structures of some of these allergens have also been evaluated to elucidate the antigenic determinants of these molecules and to explain the cross-reactivity among the various allergens.

  8. Current Overview of Allergens of Plant Pathogenesis Related Protein Families

    Science.gov (United States)

    Sinha, Mau; Singh, Rashmi Prabha; Kushwaha, Gajraj Singh; Iqbal, Naseer; Singh, Avinash; Kaushik, Sanket; Sharma, Sujata; Singh, Tej P.

    2014-01-01

    Pathogenesis related (PR) proteins are one of the major sources of plant derived allergens. These proteins are induced by the plants as a defense response system in stress conditions like microbial and insect infections, wounding, exposure to harsh chemicals, and atmospheric conditions. However, some plant tissues that are more exposed to environmental conditions like UV irradiation and insect or fungal attacks express these proteins constitutively. These proteins are mostly resistant to proteases and most of them show considerable stability at low pH. Many of these plant pathogenesis related proteins are found to act as food allergens, latex allergens, and pollen allergens. Proteins having similar amino acid sequences among the members of PR proteins may be responsible for cross-reactivity among allergens from diverse plants. This review analyzes the different pathogenesis related protein families that have been reported as allergens. Proteins of these families have been characterized in regard to their biological functions, amino acid sequence, and cross-reactivity. The three-dimensional structures of some of these allergens have also been evaluated to elucidate the antigenic determinants of these molecules and to explain the cross-reactivity among the various allergens. PMID:24696647

  9. The Place of Culture in the Current International Relations

    Directory of Open Access Journals (Sweden)

    Constantin Frosin

    2011-05-01

    Full Text Available Culture and international relations easily appear to be mutually contradictory terms. To speak of "culture" is to invoke the creative capacities of human beings, to point, for example, to the constitutive role of values and visions, to the power of language and aesthetic expression, to communities great and small engaged in reconstructing normative aspirations and reshaping the possibilities for a decent way of life. To speak of "international relations," by contrast, is to draw upon an altogether bleaker account of the human condition, to refer to missiles and bombs, trade figures and debts, statesmanship and diplomacy, intrigue and force. It is to echo assertions about naked power and the sacrifice of cultural creativity and normative aspiration to the supposedly more enduring determinations of survival or supremacy. From the dark depths of international relations, the term culture takes on an aura of frivolity. It appears to refer to the idealistic and utopian, to the veneer of civilized decency that is always stripped away by the harsh realities of power politics and international conflict. This work aims at showing the contrary.

  10. HISTORICAL CRITICAL PEDAGOGY AND OBJECTIVE KNOWLEDGE VERSUS THE MULTICULTURALISM AND RELATIVISM CURRENT ACADEMIC DEBATE

    Directory of Open Access Journals (Sweden)

    Julia Malanchen

    2015-06-01

    Full Text Available The article discusses the existing antagonistic understanding among the authors who discuss curriculum from the multiculturalist perspective and the authors of the Historical-Critical Pedagogy. The aim is to explain the postmodern relativists bases and multiculturalism, which opposes the defense of objective knowledge as central to the organization of a curriculum. Finally we point out what content should integrate an academic, with the objective, human development, human emancipation and social transformation, which allow the human being aim to provide social and consciously so increasingly free and universal.

  11. Strategies to translate knowledge related to common musculoskeletal conditions into physiotherapy practice: a systematic review.

    Science.gov (United States)

    Bérubé, Marie-Ève; Poitras, Stéphane; Bastien, Marc; Laliberté, Lydie-Anne; Lacharité, Anyck; Gross, Douglas P

    2017-05-26

    Many physiotherapists underuse evidence-based practice guidelines or recommendations when treating patients with musculoskeletal disorders, yet synthesis of knowledge translation interventions used within the field of physiotherapy fails to offer clear conclusions to guide the implementation of clinical practice guidelines. To evaluate the effectiveness of various knowledge translation interventions used to implement changes in the practice of current physiotherapists treating common musculoskeletal issues. A computerized literature search of MEDLINE, CINHAL and ProQuest of systematic reviews (from inception until May 2016) and primary research studies (from January 2010 until June 2016). Eligibility criteria specified articles evaluating interventions for translating knowledge into physiotherapy practice. Two reviewers independently screened the titles and abstracts, reviewed full-text articles, performed data extraction, and performed quality assessment. Of a total of 13014 articles located and titles and abstracts screened, 34 studies met the inclusion criteria, including three overlapping publications, resulting in 31 individual studies. Knowledge translation interventions appear to have resulted in a positive change in physiotherapist beliefs, attitudes, skills and guideline awareness. However, no consistent improvement in clinical practice, patient and economic outcomes were observed. The studies included had small sample sizes and low methodological quality. The heterogeneity of the studies was not conducive to pooling the data. The intensity and type of knowledge translation intervention seem to have an effect on practice change. More research targeting financial, organizational and regulatory knowledge translation interventions is needed. Copyright © 2017 Chartered Society of Physiotherapy. Published by Elsevier Ltd. All rights reserved.

  12. Bidirectional relations between phonological awareness and letter knowledge in preschool revisited: A growth curve analysis of the relation between two code-related skills.

    Science.gov (United States)

    Lerner, Matthew D; Lonigan, Christopher J

    2016-04-01

    Despite the importance of phonological awareness for the development of reading in alphabetic languages, little attention has been paid to its developmental origins. In this study, dual-process, latent growth models were used to examine patterns of bidirectional relations between letter knowledge and phonological awareness during preschool. The sample comprised 358 children (mean age=48.60 months, SD=7.26). Growth models were used to quantify the unique longitudinal relations between the initial level of each skill and growth in the other skill during the preschool year, after controlling for initial level of the same skill, vocabulary, age, and growth in the code-related skill being used as a predictor. Letter-name knowledge and phonological awareness were bidirectionally related; the initial level of each uniquely predicted growth in the other. Initial letter-sound knowledge and phonological awareness growth were not uniquely related, and vocabulary was not related to growth in phonological awareness. These findings extend the evidence of the relation between letter knowledge and phonological awareness to supra-phonemic tasks, indicating that this bidirectional relation begins at an earlier point in the development of phonological awareness than previously reported. In addition, these findings help to rule out general growth in letter knowledge and phonological awareness as an alternative explanation for the bidirectional relation between these two code-related skills. Copyright © 2015 Elsevier Inc. All rights reserved.

  13. Asthma-related emergency department use: current perspectives

    Directory of Open Access Journals (Sweden)

    Johnson LH

    2016-07-01

    Full Text Available Laurie H Johnson,1 Patricia Chambers,1 Judith W Dexheimer1,2 1Division of Emergency Medicine, 2Division of Biomedical Informatics, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA Abstract: Asthma is one of the most common chronic pediatric diseases. Patients with asthma often present to the emergency department for treatment for acute exacerbations. These patients may not have a primary care physician or primary care home, and thus are seeking care in the emergency department. Asthma care in the emergency department is multifaceted to treat asthma patients appropriately and provide quality care. National and international guidelines exist to help drive clinical care. Electronic and paper-based tools exist for both physicians and patients to help improve emergency, home, and preventive care. Treatment of patients with asthma should include the acute exacerbation, long-term management of controller medications, and controlling triggers in the home environment. We will address the current state of asthma research in emergency medicine in the US, and discuss some of the resources being used to help provide a medical home and improve care for patients who suffer from acute asthma exacerbations. Keywords: asthma, pediatric, emergency department

  14. The ecotoxicity of graphene family materials: current status, knowledge gaps and future needs

    Science.gov (United States)

    Jastrzębska, Agnieszka Maria; Olszyna, Andrzej Roman

    2015-01-01

    Recently, graphene family materials (GFMs) have been introduced among all fields of science and still get numerous attention. Also, the applicability of these materials in many areas makes them very attractive. GFMs have attracted both academic and industrial interest as they can produce a dramatic improvement in materials properties at very low filler content. The aim of this review is to identify, summarize, and present the first available information on the influence of GFMs on soil and water environment as well as identify the knowledge gaps and indicate the directions for the next generation of the original scientific investigations. The paper also presents our first preliminary impact assessment and potential pathways of GFMs distribution in the environment. We used as an example the reduced graphene oxide/Al2O3 nanocomposite (RGO/Al2O3) that has been previously designed and synthesized by us. Authors believe that further work should focus on improvement of characterization methodology applicable for ecotoxicity analyses and possible interactions between GFMs and different living ecosystems. Consequently, the potential impact of graphene and its derivatives on environmental health is a matter of academic interest. However, potential hazards sufficient for risk assessment and concerned with GFMs usage in consumer products first need to be investigated and identified. Further research should focus on gathering knowledge on GFMs properties for life cycle analyses, which still poses a great challenge for scientists.

  15. Diabetes related knowledge among residents and nurses: a multicenter study in Karachi, Pakistan

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    Ahmed Asma

    2012-09-01

    Full Text Available Abstract Background Assessment of knowledge among resident trainees and nurses is very important since majority of patients admitted in hospital have underlying diabetes which could lead to adverse clinical outcomes if not managed efficiently. Therefore, the purpose of this study was to evaluate and compare the knowledge related to the management of diabetes among registered nurses (RN and trainee residents of internal medicine (IMR, family medicine (FMR and surgery (SR at tertiary care hospitals of Karachi, Pakistan. Methods A validated questionnaire consisting of 21 open ended questions related to diabetes awareness was acquired through a study done at Thomas Jefferson University Hospital, Philadelphia with the permission of primary author. Results 169 IMR, 27 FMR, 86 SR and 99 RN completed a questionnaire that assessed the knowledge related to different aspects of management of diabetes. The results were further stratified by participant's specialty and level of training. The percentage of knowledge based questions answered correctly was found to be low. The overall mean correct percentage among all the participants was 50% +/- 21. There was no statistical difference in terms of knowledge between IMR & FMR residents (64% +/- 14 vs. 60% +/- 16, p = 0.47 respectively. The total scores of SR and RN were quite low (40% +/- 16 & 31% +/- 15 respectively.SR and RN were found to have profound deficit in both inpatient and outpatient knowledge of diabetes. We did not observe any improvement in level of knowledge of FMR & SR with increase in duration of their training (p = 0.47 & 0.80 respectively. In contrast, improvement in the level of knowledge of IMR was observed from first to second year of their training (p = 0.03 with no further improvement thereafter. RN's didn't respond correctly on most of the items related to in-patient management of diabetes (Mean score 40% +/- 20. Conclusion As there are no prior studies in our setting

  16. The influence of event-related knowledge on verb-argument processing in aphasia.

    Science.gov (United States)

    Dickey, Michael Walsh; Warren, Tessa

    2015-01-01

    Event-related conceptual knowledge outside the language system rapidly affects verb-argument processing in unimpaired adults (McRae and Matsuki, 2009). Some have argued that verb-argument processing is in fact reducible to the activation of such event-related knowledge. However, data favoring this conclusion have come primarily from college-aged healthy adults, for whom both linguistic and conceptual semantic processing is fast and automatic. This study examined the influence of event-related knowledge on verb-argument processing among adults with aphasia (n = 8) and older unimpaired controls (n = 60), in two self-paced reading studies. Participants read sentences containing a plausible verb-argument combination (Mary used a knife to chop the large carrots before dinner), a combination that violated event-related world knowledge (Mary used some bleach to clean the large carrots before dinner), or a combination that violated the verb's selectional restrictions (Mary used a pump to inflate the large carrots before dinner). The participants with aphasia naturally split into two groups: Group 1 (n = 4) had conceptual-semantic impairments (evidenced by poor performance on tasks like Pyramids & Palm Trees) but reasonably intact language processing (higher Western Aphasia Battery Aphasia Quotients), while Group 2 (n = 4) had intact conceptual semantics but poorer language processing. Older unimpaired controls and aphasic Group 1 showed rapid on-line disruption for sentences with selectional-restriction violations (SRVs) and event-related knowledge violations, and also showed SRV-specific penalties in sentence-final acceptability judgments (Experiment 1) and comprehension questions (Experiment 2). In contrast, Group 2 showed very few reliable differences across conditions in either on-line or off-line measures. This difference between aphasic groups suggests that verb-related information and event-related knowledge may be dissociated in aphasia. Furthermore, it suggests

  17. Relative Importance and Knowledge Distribution of Medicinal Plants in a Kichwa Community in the Ecuadorian Amazon

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    Brian Joseph Doyle

    2017-01-01

    Full Text Available Traditional knowledge, such as knowledge of the use of plants as medicine, influences how indigenous people manage forest resources. Gender and age-associated differences in traditional knowledge may impact forest resource management because of the traditional division of labor. We interviewed 18 men and 18 women between 9 and 74 years old in San José de Payamino, an indigenous community of the Kichwa ethnicity in the Ecuadorian Amazon, to determine if there are gender or age-associated differences in medicinal plant knowledge among the Payamino people and to identify the most important species from a sample of medicinal plants. Individuals were interviewed using a tablet that displayed images of 34 plants, which had been cited by traditional healers in the community. Quantitative analysis provided insight into the relative importance of plants in the sample as well as the distribution of medicinal plant knowledge among members of the community. The most important plants were Tradescantia zanonia and Monolena primuliflora. These plants should be considered candidates for further investigation. There was a positive correlation between age and knowledge of medicinal plants, but no significant difference between genders. Our results suggest that an interview method that relies on digital images can reveal differences in the importance of medicinal plants as well as provide insight into the distribution of traditional medical knowledge. While men and women are likely to manage forest resources similarly, younger members of the community may not have the same regard for forest resources as their elder counterparts.

  18. Diabetes Mellitus-Related Knowledge among University Students in Ajman, United Arab Emirates.

    Science.gov (United States)

    Khan, Nelofer; Gomathi, Kadayam G; Shehnaz, Syed Ilyas; Muttappallymyalil, Jayakumary

    2012-08-01

    The aim of this study was to assess diabetes mellitus (DM)-related knowledge and practices among university students enrolled in non-health care related professional courses in the United Arab Emirates. A pre-tested questionnaire assessing the knowledge of DM was administered to the above-mentioned students. Data collected were transferred to PASW Statistics (Chicago, IL, USA, Version 18) and analysed. Data on 168 university students (47 males and 121 females) were included in the analysis. Of the participants, 25% were overweight or obese and only 27% exercised regularly. Regarding their knowledge of DM, 70% knew that it is characterised by high blood sugar levels and identified family history as a major risk factor. Surprisingly, only just over half could link obesity and physical inactivity as risk factors for developing DM, or could identify an excessive feeling of thirst, frequent urination, and weight loss as symptoms. Knowledge of the complications of diabetes, including gangrene, loss of sensation in limbs, oral and dental complications, recurrent infections, and risk for cardiovascular disease got a moderate response. Knowledge of diabetes was found to be higher in females compared to males. No significant differences were observed in the health behaviour of participants with or without a family history of DM. Our study revealed that in spite of exposure to various sources of information, the participants' level of DM-related knowledge was not adequate. We recommend the engagement of health professionals in educational settings in order to enhance health-related knowledge and inculcate healthy lifestyle practices in students.

  19. Microbiology of Wind-eroded Sediments: Current Knowledge and Future Research Directions

    Science.gov (United States)

    Wind erosion is a threat to the sustainability and productivity of soils that takes place at local, regional, and global scales. Current estimates of cost of wind erosion have not included the costs associated with the loss of soil biodiversity and reduced ecosystem functions. Microorganisms carrie...

  20. Does self-consciousness mediate the relation between self-talk and self-knowledge?

    Science.gov (United States)

    Schneider, Johann F; Pospeschill, Markus; Ranger, Jochen

    2005-04-01

    Building on Morin's understanding of the relations among self-talk, self-consciousness, and self-knowledge, this study examined the hypothesis that functional and dysfunctional self-consciousness mediate between self-talk and self-knowledge. A self-report questionnaire including 10 scales assessing different aspects of Self-talk, Self-consciousness, and Self-knowledge was administered to 200 German undergraduate university students (95 women, 105 men). Mediation analysis showed that the observed negative relationship between Self-talk and Self-knowledge was mediated by Dysfunctional Self-consciousness, while Functional Self-consciousness acted like a supressor variable. The discussion focuses on limitations of the present measures of Self-talk.

  1. The Importance of Knowledge Management and Trust in Relation to Disaster Response

    Directory of Open Access Journals (Sweden)

    Nicole Tanner

    2010-11-01

    Full Text Available

     

    This article investigates the importance of Knowledge Management (KM and trust in disaster response. In KM, a lack of trust and non-reciprocity of information can hinder the process of knowledge transfer. Similarly, a lack of KM coinciding with a disaster can lead to public distrust of those in positions of authority. In the Exxon Valdez oil spill disaster, many people were impacted by issues of trust related to the transfer of knowledge and improper KM. However, mistrust due to poor KM is not unique to the Exxon Valdez spill. This article also discusses other disaster scenarios, such as the aftermath of Hurricane Katrina and the Central Natural Gas Corporation?s business disaster, which were both exacerbated by poor KM and breaks in the knowledge transfer process.

  2. The linkage between car-related fringe benefits and the travel behavior of knowledge workers

    DEFF Research Database (Denmark)

    Bendit, Eduard; Frenkel, Amnon; Kaplan, Sigal

    2011-01-01

    This study focuses on the linkage between car-related fringe benefits and the travel behavior of knowledge workers in commute and leisure trips. Specifically, this study compares the commuting and leisure travel behavior of knowledge workers who receive either a company-car or car allowance...... and travel times and non-sustainable transport modes, and (iii) high frequency of long-distance leisure trips. Policy implications include (i) directing policies towards reducing car ownership induced by car-related fringe benefits, (ii) encouraging company-car holders to ‘pay their way’, and (iii......) encouraging workers to use sustainable transport modes for commuting and leisure travel....

  3. Chilean jagged lobster, Projasus bahamondei, in the southeastern Pacific Ocean: current state of knowledge

    Directory of Open Access Journals (Sweden)

    Patricio M Arana

    2014-03-01

    Full Text Available The Chilean jagged lobster (Projasus bahamondei is a deep-water crustacean (175-550 m occurring in certain areas of the southeastern Pacific Ocean, including the Nazca Ridge, Desventuradas Islands, the Juan Fernandez archipelago and ridge, and the continental slope off the central coast of Chile. This review describes the taxonomic status, geographical and bathymetric distribution, some biological aspects and habitat characteristics of this species. Additionally, both artisanal and industrial exploitation attempts made within the region are detailed, as well as fishing operation results, chemical composition, different elaboration procedures and the destination of the catch. The main objectives of this review are to contribute to the knowledge of P. bahamondei as a component of the deep-sea ecosystem and to highlight its importance as a potential fishery resource.

  4. Hydrogeology and management of freshwater lenses on atoll islands: Review of current knowledge and research needs

    Science.gov (United States)

    Werner, Adrian D.; Sharp, Hannah K.; Galvis, Sandra C.; Post, Vincent E. A.; Sinclair, Peter

    2017-08-01

    On atoll islands, fresh groundwater occurs as a buoyant lens-shaped body surrounded by saltwater derived from the sea, forming the main freshwater source for many island communities. A review of the state of knowledge of atoll island groundwater is overdue given their susceptibility to adverse impacts, and the task to address water access and sanitation issues within the United Nations' Sustainable Development Goals framework before the year 2030. In this article, we review available literature to summarise the key processes, investigation techniques and management approaches of atoll island groundwater systems. Over fifty years of investigation has led to important advancements in the understanding of atoll hydrogeology, but a paucity of hydrogeological data persists on all but a small number of atoll islands. We find that the combined effects of buoyancy forces, complex geology, tides, episodic ocean events, strong climatic variability and human impacts create highly dynamic fresh groundwater lenses. Methods used to quantify freshwater availability range from simple empirical relationships to three-dimensional density-dependent models. Generic atoll island numerical models have proven popular in trying to unravel the individual factors controlling fresh groundwater lens behaviour. Major challenges face the inhabitants and custodians of atoll island aquifers, with rising anthropogenic stresses compounded by the threats of climate variability and change, sea-level rise, and some atolls already extracting freshwater at or above sustainability limits. We find that the study of atoll groundwater systems remains a critical area for further research effort to address persistent knowledge gaps, which lead to high uncertainties in water security issues for both island residents and surrounding environs.

  5. Current concepts on gingival fibromatosis-related syndromes.

    Science.gov (United States)

    Poulopoulos, Athanasios; Kittas, Dimitrios; Sarigelou, Asimina

    2011-08-01

    Gingival fibromatosis is a rare, benign, slowly-growing fibrous overgrowth of the gingiva, with great genetic and clinical heterogeneity. Gingival fibromatosis/overgrowth can be inherited as an isolated trait (hereditary gingival fibromatosis) and/or as a component of a syndrome, or it can be drug induced. As a clinical manifestation of a syndrome, gingival fibromatosis is usually associated with generalized hypertrichosis, mental retardation, or epilepsy. Gingival fibromatosis and its related syndromes are mainly inherited in an autosomal-dominant manner, but autosomal-recessive inheritance has also been reported. Clinical syndromic presentation includes Zimmermann-Laband syndrome, Ramon syndrome, Rutherford syndrome, Cowden syndrome, Cross syndrome, Göhlich-Ratmann syndrome, Avani syndrome, and I-cell disease. However, a phenotypic overlap has been suggested, as many combinations of their systemic manifestations have been reported. Treatment of choice is usually gingivectomy with gingivoplasty. Before any therapy, clinical practitioners must take into consideration the clinical course of a particular syndrome and every possible functional and esthetic disorder.

  6. A protein relational database and protein family knowledge bases to facilitate structure-based design analyses.

    Science.gov (United States)

    Mobilio, Dominick; Walker, Gary; Brooijmans, Natasja; Nilakantan, Ramaswamy; Denny, R Aldrin; Dejoannis, Jason; Feyfant, Eric; Kowticwar, Rupesh K; Mankala, Jyoti; Palli, Satish; Punyamantula, Sairam; Tatipally, Maneesh; John, Reji K; Humblet, Christine

    2010-08-01

    The Protein Data Bank is the most comprehensive source of experimental macromolecular structures. It can, however, be difficult at times to locate relevant structures with the Protein Data Bank search interface. This is particularly true when searching for complexes containing specific interactions between protein and ligand atoms. Moreover, searching within a family of proteins can be tedious. For example, one cannot search for some conserved residue as residue numbers vary across structures. We describe herein three databases, Protein Relational Database, Kinase Knowledge Base, and Matrix Metalloproteinase Knowledge Base, containing protein structures from the Protein Data Bank. In Protein Relational Database, atom-atom distances between protein and ligand have been precalculated allowing for millisecond retrieval based on atom identity and distance constraints. Ring centroids, centroid-centroid and centroid-atom distances and angles have also been included permitting queries for pi-stacking interactions and other structural motifs involving rings. Other geometric features can be searched through the inclusion of residue pair and triplet distances. In Kinase Knowledge Base and Matrix Metalloproteinase Knowledge Base, the catalytic domains have been aligned into common residue numbering schemes. Thus, by searching across Protein Relational Database and Kinase Knowledge Base, one can easily retrieve structures wherein, for example, a ligand of interest is making contact with the gatekeeper residue.

  7. Current knowledge about and recommendations for ocular methicillin-resistant Staphylococcus aureus.

    Science.gov (United States)

    Mah, Francis S; Davidson, Richard; Holland, Edward J; Hovanesian, John; John, Thomas; Kanellopoulos, John; Shamie, Neda; Starr, Christopher; Vroman, David; Kim, Terry

    2014-11-01

    Staphylococcus aureus is the most important and common pathogen that infects patients following cataract surgery, laser in situ keratomileusis, and photorefractive keratectomy. It is reported to be the second most common pathogen causing bacterial keratitis around the world. Of special concern are increasing reports of postoperative methicillin-resistant S aureus (MRSA) infection. For example, MRSA wound infections have been reported with clear corneal phacoemulsification wounds, penetrating keratoplasty, lamellar keratoplasty, and following ex vivo epithelial transplantation associated with amniotic membrane grafts. These and other data suggest that MRSA has become increasingly prevalent worldwide. In this article, we review the current medical literature and describe the current challenge of ocular MRSA infections. Recommendations are made based on an evidence-based review to identify, treat, and possibly reduce the overall problem of this organism. No author has a financial or proprietary interest in any material or method mentioned. Copyright © 2014 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

  8. Chronic diseases knowledge and related factors among the elderly in Jinan, China.

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    Yapei Song

    Full Text Available BACKGROUND: It has been reported that the prevalence of chronic diseases is high among old people and they have poor chronic diseases knowledge. This study was therefore designed to evaluate the awareness rate of chronic diseases knowledge among people aged over 60 years, to explore its related factors and to provide evidence for future health education. METHODS: A cross-sectional study was conducted from April to August in 2011. People aged 60 years and above from 3 communities in Jinan were selected by cluster sampling. Nine hundred and twenty five participants were interviewed face-to-face using a structured questionnaire. RESULTS: The awareness rates of chronic diseases knowledge varied from 29.5% to 90.2%. Four healthy lifestyles including quitting smoking and less drinking, keeping broad-minded, maintaining balanced diet and moderate physical activity were best known (from 86.3% to 90.2%. The least known knowledge were 2 complications of hypertension: nephropathy (29.5% and retinopathy (37.2%. Participants with the following characteristics or behaviors were more likely to have higher chronic diseases knowledge: younger age, female, Han Chinese, higher level of education, having health insurance, participating in societies, having family history of chronic diseases, frequently gathering with friends/relatives, usually going to provincial hospitals/hospitals affiliated with medical universities, usually going to municipal hospitals and usually going to community health center/station. CONCLUSIONS: Old people in Jinan had incomplete chronic diseases knowledge and the overall awareness rate was not high. The older people's chronic diseases knowledge should be improved and health education programs should target males, older people with lower educational level, having no health insurance, having no family history of chronic diseases, participating in no societies, and less frequently gathering with friends/relatives. Also, lower level medical

  9. Current knowledge on evidence-based shockwave treatments for shoulder pathology.

    Science.gov (United States)

    Moya, Daniel; Ramón, Silvia; Guiloff, Leonardo; Gerdesmeyer, Ludger

    2015-12-01

    Shoulder pain is one of the most common musculoskeletal pathologies. Treatment by ESWT (extracorporeal shockwave therapy) has emerged as an alternative when conservative treatment fails in rotator cuff calcific tendinopathy, prior to invasive procedures. The clinical efficacy of ESWT in non-calcific tendinopathy remains controversial. The good results in the treatment of rotator cuff calcifications, have led to indications of ESWT being expanded to other shoulder pathologies. We review the current state of indications and evidence based practice.

  10. Family planning knowledge and current use of contraception among the Mru indigenous women in Bangladesh: a multivariate analysis

    Directory of Open Access Journals (Sweden)

    Islam MR

    2012-02-01

    Full Text Available M Rakibul Islam1, Gunnar Thorvaldsen21Bangladesh Agricultural University, Bangladesh; 2Norwegian Historical Data Centre, University of Tromsø, NorwayBackground: This article aims to understand the family planning (FP knowledge and current use of contraception and its predictors among women of the Mru people – the most underprivileged indigenous community in Bangladesh.Methods: In this study, 374 currently married Mru women were interviewed and selected purposively from three upazilas (administrative subdistricts of the Bandarban area, where most of the Mru people live. The association between the variables was assessed in bivariate analysis using the Chi-square test and binary logistic regression models were employed to explore the predictors of FP knowledge and current use of contraception among the Mru women.Results: Only about 40% of respondents had ever heard FP messages or about FP methods – two-fifths of the national figure (99.9%. The current use of contraception was much lower (25.1% among the Mru people than at the national level (55.8%. Among both modern and traditional methods, the contraceptive pill ranked first. About two-thirds (66.0% of married women used this method – more than two times than the national figure (28.5%. On the other hand, the prevalence of male methods was comparatively lower than at the national level. Logistic regression models revealed that place of residence, religion, age, school attendance, husband's school attendance, service provided in the community, distance to the service center, and exposure to mass media had significant effects on knowledge of FP and on use of contraception.Conclusion: Education for mothers and vernacular language-based doorstep FP programs with special emphasis on awareness are suggested for the community.Keywords: family planning, contraceptive use, the Mru, logistic regression, Bangladesh

  11. Health-related beliefs and consumer knowledge as determinants of fish consumption

    DEFF Research Database (Denmark)

    Pieniak, Zuzanna; Verbeke, Wim; Scholderer, Joachim

    2010-01-01

    consumption: consumers' knowledge and health-related beliefs, as well as the relationship between those variables, socio-demographics and fish consumption frequency, using data from five European countries. Methods: A cross-sectional consumer survey was carried out in 2004 with representative household......Background: Despite scientific evidence on the positive effects of seafood consumption on human health, the consumption of fish remains below the recommended intake levels for the majority of Europeans. The present study aimed to explore cultural differences in potential determinants of fish...... that eating fish is healthy, their interest in healthy eating and objective fish-related nutrition knowledge, positively, but only weakly, influenced fish consumption frequency. Subjective knowledge was found to be a stronger predictor of fish consumption than the previously noted factors. Age and education...

  12. HORSE SPECIES SYMPOSIUM: The microbiome of the horse hindgut: History and current knowledge.

    Science.gov (United States)

    Julliand, V; Grimm, P

    2016-06-01

    In the early 1990s, the equine hindgut microbial ecosystem looked like a "black box." Its vital role in hydrolyzing and fermenting fiber, thus providing energy to the host, was recognized. Although there was a critical lack of information on the hindgut microbes, their role in preventing intestinal diseases was suggested. Traditionally, the microbes of the horse hindgut were studied using culture-dependent techniques. More recently, culture-independent methods have been used and provided further insight. This review presents the history and updated knowledge regarding the microbes that live inside the different intestinal ecosystems and which collective genomes compose the hindgut microbiome. In the first section, the quantification and diversity are described for each microbial community as well as the implication of plant fiber degradation and their crucial role for an herbivore host. The microbial communities are presented in chronological order of discovery: due to their large size, protozoa were brought to light as early as 1843 in the horse cecum; in 1897, bacteria were described in the horse intestine; as early as 1910, monoflagellated eukaryotic organisms resembling protozoa were observed in the horse cecum; since then, they have been identified to be zoospores of anaerobic fungi; in 1970, bacteriophage-like particles were recognized in the cecum and colon of pony and horse; and finally, in 1996, archaea were identified in the horse cecum. The second section discusses the variations that can occur between digestive segments or between individuals. The representativeness of the fecal microbiota to the hindgut one is debated, especially as the majority of recent studies conducted on the horse hindgut are in fact focused on the feces, rather than the cecum or colon. Also, the representation of microbiota between individuals is questioned. It has long been suggested in the literature that some ponies or horses that were more susceptible to intestinal diseases

  13. Longitudinal relations between adolescent and parental behaviors, parental knowledge, and internalizing behaviors among urban adolescents.

    Science.gov (United States)

    Garthe, Rachel C; Sullivan, Terri; Kliewer, Wendy

    2015-04-01

    High prevalence rates of depression and anxiety among adolescents underscore the importance of identifying parental and adolescent behaviors that may lessen the risk for these outcomes. Previous research has shown that parental acceptance, parental knowledge, and child disclosure are negatively associated with internalizing behaviors. It is also important to explore the impact of internalizing behaviors on these parental and child constructs. The current study examined longitudinal relationships between parental acceptance, parental knowledge, child disclosure, and internalizing symptoms across a one-year time period. Participants were 358 adolescents (54 % female) and their primary caregivers, who were primarily African American (92 %). Parents and adolescents provided data through face-to-face interviews. Results showed that parental knowledge and parental acceptance predicted child disclosure, and child disclosure predicted parental knowledge one year later. Higher levels of parental acceptance predicted lower levels of adolescent-reported depressive symptoms, while higher levels of parental report of adolescents' internalizing symptoms predicted lower levels of parental knowledge. No differences in the strength of these relationships were found across grade or gender. These findings highlight the role of the adolescent's perceived acceptance by parents in promoting children's disclosure, and the benefits of parental acceptance in decreasing depressive symptoms over time. Overall, these results show the impact that both adolescent and parental behaviors and internalizing behaviors have on each other across time.

  14. Current knowledge of prenatal diagnosis of mosaic autosomal trisomy in amniocytes: karyotype/phenotype correlations.

    Science.gov (United States)

    Wallerstein, Robert; Misra, Sonya; Dugar, R Bryce; Alem, Monika; Mazzoni, Ronit; Garabedian, Matthew J

    2015-09-01

    Genetic counseling for prenatal diagnosis of autosomal trisomy is complex because of the uncertainty of outcome, which is important for management decisions. Compilation of cases of prenatally diagnosed autosomal trisomies in amniocytes has been done previously in an attempt to elucidate the clinical phenotype of these pregnancies. It has been greater than a decade since these studies were completed. To update this work, we reviewed cases reported in the literature since that time. These cases are correlated with the prior reports to increase knowledge about outcomes and to hopefully improve the data available for genetic counseling. The risk of abnormal outcome can be summarized as: very high risk (>60%) for 47,+2/46; 47,+9/46; 47,+16/46; 47,+20/46; and 47,+22/46; high risk (40-59%) for 47,+5/46; 47,+14/46; and 47,+15/46; moderately high risk (20-39%) for 47,+7/46 47,+12/46; and 47,+17/46; moderate risk (up to 19%) for 47,+6/46 and 47,+8/46, and none were low risk. 47,+6/46 was originally indeterminate, 47,+7/46 was originally moderate risk, 47,+9/46 was originally high risk, and 47,+17/46 was originally low risk. © 2015 John Wiley & Sons, Ltd.

  15. Historical first descriptions of Cajal-Retzius cells: from pioneer studies to current knowledge

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    Vanessa eGil

    2014-05-01

    Full Text Available Santiago Ramón y Cajal developed a great body of scientific research during the last decade of 19th century, mainly between 1888 and 1892, when he published more than 30 manuscripts. The neuronal theory, the structure of dendrites and spines, and fine microscopic descriptions of numerous neural circuits are among these studies. In addition, numerous cell types (neuronal and glial were described by Ramón y Cajal during this time using this ‘reazione nera’ or Golgi method. Among these neurons were the special cells of the molecular layer of the neocortex. These cells were also termed Cajal cells or Retzius cells by other colleagues. Today these cells are known as Cajal-Retzius cells. From the earliest description, several biological aspects of these fascinating cells have been analyzed (e.g., cell morphology, physiological properties, origin and cellular fate, putative function during cortical development, etc. In this review we will summarize in a temporal basis the emerging knowledge concerning this cell population with specific attention the pioneer studies of Santiago Ramón y Cajal.

  16. A review of current knowledge of the complement system and the therapeutic opportunities in inflammatory arthritis.

    Science.gov (United States)

    Mizuno, M

    2006-01-01

    The complement activation system, a key component of the innate immune system, protects the host from microorganisms such as bacteria, and other foreign threats including abnormal cells. However, it is also double-edged in that it can have negative effects in the host; excessive complement activation damages the host and can even kill in anaphylactic shock and septic shock. Regulation of the complement system is a useful strategy to control inflammatory diseases, including inflammatory arthritis. Rheumatoid arthritis is a common inflammatory disease worldwide. Many medicines are developed to control inflammation, including recently developed biological response modifiers such as anti-TNF and IL-6 agents. Nevertheless, in some patients disease remains difficult to control because of complications, side effects and tolerance of medicines. In inflammatory arthritis, including rheumatoid arthritis, there is abundant evidence implicating complement activation in humans and animal models. Therefore, anti-complement agents might be beneficial as part of clinical treatment. However, at present, there are still no applicable agents for therapeutic regulation of excessive complement activation in chronic disease. Novel agents in development might be useful as a strategy to control complement activation. Here I describe recent knowledge of the complement system in inflammatory arthritis, the recent developments in anti-complement agents and their considerable potential for the future.

  17. Current knowledge of environmental exposure in children during the sensitive developmental periods.

    Science.gov (United States)

    Perlroth, Norma Helena; Castelo Branco, Christina Wyss

    This study aims to identify the scientific evidence on the risks and effects of exposure to environmental contaminants in children during sensitive developmental periods. The search was performed in the Bireme database, using the terms: children's health, environmental exposure, health vulnerability, toxicity pathways and developmental disabilities in the LILACS, MEDLINE and SciELO systems. Children differ from adults in their unique physiological and behavioral characteristics and the potential exposure to risks caused by several threats in the environment. Exposure to toxic agents is analyzed through toxicokinetic processes in the several systems and organs during the sensitive phases of child development. The caused effects are reflected in the increased prevalence of congenital malformations, diarrhea, asthma, cancer, endocrine and neurological disorders, among others, with negative impacts throughout adult life. To identify the causes and understand the mechanisms involved in the genesis of these diseases is a challenge for science, as there is still a lack of knowledge on children's susceptibility to many environmental contaminants. Prevention policies and more research on child environmental health, improving the recording and surveillance of environmental risks to children's health, should be an ongoing priority in the public health field. Copyright © 2016 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda. All rights reserved.

  18. Q Fever: current state of knowledge and perspectives of research of a neglected zoonosis.

    Science.gov (United States)

    Porter, Sarah Rebecca; Czaplicki, Guy; Mainil, Jacques; Guattéo, Raphaël; Saegerman, Claude

    2011-01-01

    Q fever is an ubiquitous zoonosis caused by an resistant intracellular bacterium, Coxiella burnetii. In certain areas, Q fever can be a severe public health problem, and awareness of the disease must be promoted worldwide. Nevertheless, knowledge of Coxiella burnetii remains limited to this day. Its resistant (intracellular and environmental) and infectious properties have been poorly investigated. Further understanding of the interactions between the infected host and the bacteria is necessary. Domestic ruminants are considered as the main reservoir of bacteria. Infected animals shed highly infectious organisms in milk, feces, urine, vaginal mucus, and, very importantly, birth products. Inhalation is the main route of infection. Frequently asymptomatic in humans and animals, Q fever can cause acute or chronic infections. Financial consequences of infection can be dramatic at herd level. Vaccination with inactive whole-cell bacteria has been performed and proved effective in humans and animals. However, inactive whole-cell vaccines present several defects. Recombinant vaccines have been developed in experimental conditions and have great potential for the future. Q fever is a challenging disease for scientists as significant further investigations are necessary. Great research opportunities are available to reach a better understanding and thus a better prevention and control of the infection.

  19. Q Fever: Current State of Knowledge and Perspectives of Research of a Neglected Zoonosis

    Directory of Open Access Journals (Sweden)

    Sarah Rebecca Porter

    2011-01-01

    Full Text Available Q fever is an ubiquitous zoonosis caused by an resistant intracellular bacterium, Coxiella burnetii. In certain areas, Q fever can be a severe public health problem, and awareness of the disease must be promoted worldwide. Nevertheless, knowledge of Coxiella burnetii remains limited to this day. Its resistant (intracellular and environmental and infectious properties have been poorly investigated. Further understanding of the interactions between the infected host and the bacteria is necessary. Domestic ruminants are considered as the main reservoir of bacteria. Infected animals shed highly infectious organisms in milk, feces, urine, vaginal mucus, and, very importantly, birth products. Inhalation is the main route of infection. Frequently asymptomatic in humans and animals, Q fever can cause acute or chronic infections. Financial consequences of infection can be dramatic at herd level. Vaccination with inactive whole-cell bacteria has been performed and proved effective in humans and animals. However, inactive whole-cell vaccines present several defects. Recombinant vaccines have been developed in experimental conditions and have great potential for the future. Q fever is a challenging disease for scientists as significant further investigations are necessary. Great research opportunities are available to reach a better understanding and thus a better prevention and control of the infection.

  20. Expanding current knowledge on the chemical composition and antioxidant activity of the genus Lactarius.

    Science.gov (United States)

    Vieira, Vanessa; Barros, Lillian; Martins, Anabela; Ferreira, Isabel C F R

    2014-12-10

    Despite the presence of toxic compounds in inedible mushrooms, the question whether the chemical nutrients and non-nutrients compositions in edible and inedible Lactarius species are similar remains unanswered. To answer this question, Lactarius citriolens Pouzar and Lactarius turpis (Weinm.) Fr., two inedible species, were studied in order to obtain information about their chemical composition and bioactivity. Free sugars, fatty acids, tocopherols, organic and phenolic acids were analysed by chromatographic techniques coupled to different detectors. L. citriolens and L. turpis methanolic extracts were tested regarding antioxidant potential (reducing power, radical scavenging activity and lipid peroxidation inhibition). The composition of macronutrients varied among the two species, but the profiles were similar between them and among other Lactarius species; L. citriolens gave the highest energy contribution, saturated fatty acids and organic acids, while the L. turpis sample was richer in free sugars, mono- and polyunsaturated fatty acids, tocopherols and phenolic compounds. L. turpis methanolic extract showed the highest antioxidant activity. The absence of hepatoxicity of the methanolic extracts was confirmed in porcine liver primary cells (in vitro conditions). The present study provided new information about wild L. citriolens and L. turpis, comparing their chemical composition and antioxidant properties with other Lactarius species, and expanding the knowledge about this genus.

  1. A Survey of Current Knowledge on Sexually Transmitted Diseases and Sexual Behaviour in Italian Adolescents

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    Francesco Drago

    2016-04-01

    Full Text Available Worldwide, 500 million people a year acquire a sexually transmitted disease (STD. Adolescents, accounting for 25% of the sexually active population, are the most affected. To analyze sexual behavior among Italian adolescents and their knowledge of STDs, with the goal of preventing their transmission, a questionnaire was administered to 2867 secondary school students (1271 males and 1596 females aged 14–21 years. For the study, 1492 students were interviewed in Genoa (Northern Italy and 1375 in Lecce (Southern Italy. For 37% of the respondents, parents and teachers were the main source of information on sex, and 95% believed that school should play the primary role in sex education. However, only 9% considered the sex education they received in school good. Noteworthy, only 0.5% of the teenagers recognized the sexually transmitted diseases from a list of diseases, and 54% of them did not know what a Pap test was. Confusion about the meaning of contraception and prevention was evident; only 22% knew that condoms and abstinence are the only methods for preventing STDs. Finally, a consistent number of students are exposed to risk factors for STDs transmission; e.g., alcohol and recreational drug use, promiscuity and improper condom use. On the basis of our study, there is an urgent need for the introduction of sex education as a proper subject in Italian schools.

  2. A Survey of Current Knowledge on Sexually Transmitted Diseases and Sexual Behaviour in Italian Adolescents.

    Science.gov (United States)

    Drago, Francesco; Ciccarese, Giulia; Zangrillo, Francesca; Gasparini, Giulia; Cogorno, Ludovica; Riva, Silvia; Javor, Sanja; Cozzani, Emanuele; Broccolo, Francesco; Esposito, Susanna; Parodi, Aurora

    2016-04-13

    Worldwide, 500 million people a year acquire a sexually transmitted disease (STD). Adolescents, accounting for 25% of the sexually active population, are the most affected. To analyze sexual behavior among Italian adolescents and their knowledge of STDs, with the goal of preventing their transmission, a questionnaire was administered to 2867 secondary school students (1271 males and 1596 females) aged 14-21 years. For the study, 1492 students were interviewed in Genoa (Northern Italy) and 1375 in Lecce (Southern Italy). For 37% of the respondents, parents and teachers were the main source of information on sex, and 95% believed that school should play the primary role in sex education. However, only 9% considered the sex education they received in school good. Noteworthy, only 0.5% of the teenagers recognized the sexually transmitted diseases from a list of diseases, and 54% of them did not know what a Pap test was. Confusion about the meaning of contraception and prevention was evident; only 22% knew that condoms and abstinence are the only methods for preventing STDs. Finally, a consistent number of students are exposed to risk factors for STDs transmission; e.g., alcohol and recreational drug use, promiscuity and improper condom use. On the basis of our study, there is an urgent need for the introduction of sex education as a proper subject in Italian schools.

  3. Self-knowledge in childhood: relations with children's imaginary companions and understanding of mind.

    Science.gov (United States)

    Davis, Paige E; Meins, Elizabeth; Fernyhough, Charles

    2011-09-01

    Relations between interior self-knowledge and (a) imaginary companion (IC) status and (b) theory of mind (ToM) abilities were investigated in a sample (N= 80) of 4- to 7-year-olds. Interior self-knowledge was assessed in terms of the extent to which children acknowledged that they (rather than an adult) were the authority on unobservable aspects of themselves (e.g., dreaming, thinking, hunger). Compared with children without an IC, those who possessed a parentally corroborated IC ascribed less interior self-knowledge to an adult, with a trend for them to assign more interior self-knowledge to themselves. Children's interior self-knowledge judgments were not associated with their ToM performance. IC status was also unrelated to ToM performance. We consider how having an IC may provide children with opportunities to distinguish between knowledge that is inaccessible to an external observer and that which an external observer may glean without being told. ©2011 The British Psychological Society.

  4. [Dengue-related knowledge, attitudes, and practices in primary schools in Tapachula, Chiapas, Mexico].

    Science.gov (United States)

    Torres, José Luis; Ordóñez, José Genaro; Vázquez-Martínez, M Guadalupe

    2014-03-01

    To identify dengue-related knowledge, attitudes, and practices among primary school students in Tapachula, Chiapas, Mexico, before and after an educational intervention. The study was carried out at 19 randomly selected public primary schools. Surveys of knowledge, attitudes, and practices were conducted before and after educational sessions with fifthand sixth-grade elementary school students. The educational strategy "Escuelas sin mosquitos" ("Schools without Mosquitoes") emphasized the importance of students' participation in taking care of their schools and homes in order to prevent dengue through vector control. Before and after the educational sessions, a total of 3 124 surveys were conducted on the knowledge, attitudes, and practices of 1 562 fifth and sixth-grade students (772 and 790 students, respectively) between 10 and 12 years of age. The students' level of knowledge was significantly higher after the implementation of the educational strategy. In comparison with the fifth-graders, the sixth-grade students both already had and also acquired significantly more knowledge of several aspects of the disease and the vector. In all the schools, there were containers with water identified as potential breeding sites, and in 68% of the schools, these containers tested positive for Aedes aegypti larvae. It was demonstrated that by implementing an educational strategy, children's knowledge, attitudes, and practices were improved in terms of taking care of their schools and promoting a change of attitude to this disease at home.

  5. Critical assessment of the current understanding/ knowledge of the framework of the Ecosystem Approach to Fisheries in the Mediterranean and Black Seas

    Directory of Open Access Journals (Sweden)

    Paolo Sartor

    2014-03-01

    Full Text Available A critical review was carried out involving experts from 17 countries, to identify, summarize and evaluate the current understanding related to the Ecosystem Approach to Fisheries management (EAF in the Mediterranean and Black Seas. The existing information available at country level, coming from research and monitoring projects and other types of activities, was explored. The evaluation was done following a standardized protocol and using simple semi-quantitative methods. The results highlighted an overall low-medium degree of fulfilment of the requirements of the EAF, with some differences related to the different issues considered. The highest scores were reported for the knowledge related to fleet structure/ behaviour and species/habitat distribution, whereas the lowest scores were reported for modelling, and socio-economic and management issues. Although only semi-quantitative, these results provided an initial picture at a broad regional level on the state of knowledge with a view to a proper implementation of the EAF in the Mediterranean and Black Seas, and identified gaps in scientific knowledge that should be covered.

  6. Integrating Multiple On-line Knowledge Bases for Disease-Lab Test Relation Extraction

    Science.gov (United States)

    Zhang, Yaoyun; Soysal, Ergin; Moon, Sungrim; Wang, Jingqi; Tao, Cui; Xu, Hua

    2015-01-01

    A computable knowledge base containing relations between diseases and lab tests would be a great resource for many biomedical informatics applications. This paper describes our initial step towards establishing a comprehensive knowledge base of disease and lab tests relations utilizing three public on-line resources. LabTestsOnline, MedlinePlus and Wikipedia are integrated to create a freely available, computable disease-lab test knowledgebase. Disease and lab test concepts are identified using MetaMap and relations between diseases and lab tests are determined based on source-specific rules. Experimental results demonstrate a high precision for relation extraction, with Wikipedia achieving the highest precision of 87%. Combining the three sources reached a recall of 51.40%, when compared with a subset of disease-lab test relations extracted from a reference book. Moreover, we found additional disease-lab test relations from on-line resources, indicating they are complementary to existing reference books for building a comprehensive disease and lab test relation knowledge base. PMID:26306271

  7. Moblogging Type and Its Relation with Usability and Development of Knowledge Management Skills for Blind Students

    Science.gov (United States)

    Mostafa, Akram Fathy

    2015-01-01

    The aim of the research is to explore the relation of mobile Blogging (Moblogging -MB) on the usability and development of Knowledge Management skills for Blind Students. The research followed a pretest and posttest quasi experimental design. Participants were 17 blind students from the third semester of the academic year 2015 in the course of…

  8. Reading Minds: The Relation between Children's Mental State Knowledge and Their Metaknowledge about Reading

    Science.gov (United States)

    Lecce, Serena; Zocchi, Silvia; Pagnin, Adriano; Palladino, Paola; Taumoepeau, Mele

    2010-01-01

    The relation between children's mental state knowledge and metaknowledge about reading was examined in 2 studies. In Study 1, 196 children (mean age = 9 years) were tested for verbal ability (VA), metaknowledge about reading, and mental state words in a story task. In Study 2, the results of Study 1 were extended by using a cross-lagged design and…

  9. "Approaching the Sacred": Directionality in the Relation between Curriculum and Knowledge Structure

    Science.gov (United States)

    Gamble, Jeanne

    2014-01-01

    Increasing pressure on all levels of educational provision, whether academic or overtly vocational, to be to "relevant" and "useful" prompts consideration of the relation between curriculum and pedagogy in terms of the internal structure of knowledge forms. Following Durkheim's distinction between "sacred" and…

  10. Risk perception: The social construction of spatial knowledge around climate change-related scenarios in Lima

    NARCIS (Netherlands)

    Miranda Sara, L.; Jameson, S.; Pfeffer, K.; Baud, I.

    2016-01-01

    Lima's environmental sustainability is threatened by increasing water scarcity, heavy rain events and limited attention for water vulnerability and climate change scenarios. In this paper we examine how knowledge construction and risk perception on water-related disaster risks and vulnerabilities

  11. Importance of Health-Related Fitness Knowledge to Increasing Physical Activity and Physical Fitness

    Science.gov (United States)

    Ferkel, Rick C.; Judge, Lawrence W.; Stodden, David F.; Griffin, Kent

    2014-01-01

    Physical inactivity is expanding across all ages in the United States. Research has documented a deficiency in health-related fitness knowledge (HRFK) among elementary- through college-aged students. The need for a credible and reliable resource that provides research-based information regarding the importance of HRFK is significant. The purpose…

  12. Microteaching Lesson Study: Mentor Interaction Structure and Its Relation to Elementary Preservice Mathematics Teacher Knowledge Development

    Science.gov (United States)

    Molina, Roxanne V.

    2012-01-01

    This study investigated Microteaching Lesson Study (MLS) and three possible MLS mentor interaction structures during the debriefing sessions in relation to elementary preservice teacher development of knowledge for teaching. One hundred three elementary preservice teachers enrolled in five different sections of a mathematics methods course at a…

  13. Risk perception: The social construction of spatial knowledge around climate change-related scenarios in Lima

    NARCIS (Netherlands)

    Miranda Sara, L.; Jameson, S.; Pfeffer, K.; Baud, I.

    2016-01-01

    Lima's environmental sustainability is threatened by increasing water scarcity, heavy rain events and limited attention for water vulnerability and climate change scenarios. In this paper we examine how knowledge construction and risk perception on water-related disaster risks and vulnerabilities af

  14. Religion-Related Caselaw Knowledge and Practices of Student Personnel Administrators in Higher Education.

    Science.gov (United States)

    Seyfried, Roma-Mary G.; Zirkel, Perry A.

    1992-01-01

    To ascertain the knowledge level and congruent practices among public college and university student-personnel administrators relating to reported court decisions based on the First Amendment religious clauses, questionnaires were sent to a sample of 250 administrators. Responses from 169 (68%) of the administrators are analyzed. (MLF)

  15. Moblogging Type and Its Relation with Usability and Development of Knowledge Management Skills for Blind Students

    Science.gov (United States)

    Mostafa, Akram Fathy

    2015-01-01

    The aim of the research is to explore the relation of mobile Blogging (Moblogging -MB) on the usability and development of Knowledge Management skills for Blind Students. The research followed a pretest and posttest quasi experimental design. Participants were 17 blind students from the third semester of the academic year 2015 in the course of…

  16. "Approaching the Sacred": Directionality in the Relation between Curriculum and Knowledge Structure

    Science.gov (United States)

    Gamble, Jeanne

    2014-01-01

    Increasing pressure on all levels of educational provision, whether academic or overtly vocational, to be to "relevant" and "useful" prompts consideration of the relation between curriculum and pedagogy in terms of the internal structure of knowledge forms. Following Durkheim's distinction between "sacred" and…

  17. Child Abuse and Aids-Related Knowledge, Attitudes and Behavior among Adolescents in Zambia

    Science.gov (United States)

    Slonim-Nevo, Vered; Mukuka, Lawrence

    2007-01-01

    Objective: To research the correlation between physical and sexual abuse by family members and AIDS-related knowledge, attitudes, self-efficacy and behavior among urban and rural adolescents in Zambia. Sample: The sample comprises 3,360 adolescents, aged 10-19, from urban and rural Zambia; 2,160 of them attended school, while 1,200 of them did…

  18. The Relative Influence on Diagnostic Decisions of Four Areas of Examiner Knowledge.

    Science.gov (United States)

    Carpenter, Linda J.

    1990-01-01

    Three vignettes about Hispanic boys referred for speech and language assessment were presented to 284 speech-language specialists. Decisions about the existence of a communication disorder, probable cause, and appropriate treatment were related to clinician specialty; experience; and knowledge of Spanish language, Hispanic culture, and…

  19. Importance of Health-Related Fitness Knowledge to Increasing Physical Activity and Physical Fitness

    Science.gov (United States)

    Ferkel, Rick C.; Judge, Lawrence W.; Stodden, David F.; Griffin, Kent

    2014-01-01

    Physical inactivity is expanding across all ages in the United States. Research has documented a deficiency in health-related fitness knowledge (HRFK) among elementary- through college-aged students. The need for a credible and reliable resource that provides research-based information regarding the importance of HRFK is significant. The purpose…

  20. Improving medical students' knowledge of genetic disease: a review of current and emerging pedagogical practices

    Directory of Open Access Journals (Sweden)

    Wolyniak MJ

    2015-10-01

    Full Text Available Michael J Wolyniak,1 Lynne T Bemis,2 Amy J Prunuske2 1Department of Biology, Hampden-Sydney College, Hampden-Sydney, VA, 2Department of Biomedical Sciences, University of Minnesota Medical School, Duluth, MN, USA Abstract: Genetics is an essential subject to be mastered by health professional students of all types. However, technological advances in genomics and recent pedagogical research have changed the way in which many medical training programs teach genetics to their students. These advances favor a more experience-based education focused primarily on developing student's critical thinking skills. In this review, we examine the current state of genetics education at both the preclinical and clinical levels and the ways in which medical and pedagogical research have guided reforms to current and emerging teaching practices in genetics. We discover exciting trends taking place in which genetics is integrated with other scientific disciplines both horizontally and vertically across medical curricula to emphasize training in scientific critical thinking skills among students via the evaluation of clinical evidence and consultation of online databases. These trends will produce future health professionals with the skills and confidence necessary to embrace the new tools of medical practice that have emerged from scientific advances in genetics, genomics, and bioinformatics. Keywords: genetics education, medical genetics, pedagogical practice, active learning, problem-based learning

  1. Mycoplasma pneumoniae: Current knowledge on nucleic acid amplification techniques and serological diagnostics

    Directory of Open Access Journals (Sweden)

    Katherine eLoens

    2016-03-01

    Full Text Available Mycoplasma pneumoniae (M. pneumoniae belongs to the class Mollicutes and has been recognized as a common cause of respiratory tract infections (RTIs, including community-acquired pneumonia (CAP, that occur worldwide and in all age groups. In addition, M. pneumoniae can simultaneously or sequentially lead to damage in the nervous system and has been associated with a wide variety of other acute and chronic diseases. During the past 10 years, the proportion of LRTI in children and adults, associated with M. pneumoniae infection has ranged from 0% to more than 50%. This variation is due to the age and the geographic location of the population examined but also due to the diagnostic methods used. The true role of M. pneumoniae in RTIs remains a challenge given the many limitations and lack of standardization of the applied diagnostic tool in most cases, with resultant wide variations in data from different studies.Correct and rapid diagnosis and/or management of M. pneumoniae infections is, however, critical to initiate appropriate antibiotic treatment and is nowadays usually done by PCR and/or serology. Several recent reviews have summarized current methods for the detection and identification of M. pneumoniae. This review will therefore provide a look at the general principles, advantages, diagnostic value, and limitations of the most currently used detection techniques for the etiological diagnosis of a M. pneumoniae infection as they evolve from research to daily practice.

  2. Social disparities, communication inequalities, and HIV/AIDS-related knowledge and attitudes in India.

    Science.gov (United States)

    Ackerson, Leland K; Ramanadhan, Shoba; Arya, Monisha; Viswanath, Kasisomayajula

    2012-10-01

    Promoting awareness, increasing knowledge, and eliminating stigma is important for stopping the spread of HIV/AIDS. The relation of social determinants and communication inequalities with HIV/AIDS-related cognitive processes has not been studied previously in India. Gender-stratified Poisson regression models of 123,459 women and 73,908 men in the 2005-2006 National Family Health Survey were used to calculate relative risk estimates and 95% confidence intervals for these associations. Results indicated that there are significant inequalities in mass media use among different social classes. Education and wealth are strongly and positively associated with awareness of HIV/AIDS and knowledge about prevention and transmission of AIDS and negatively associated with HIV/AIDS-related stigma. These associations attenuated when use of various mass media types were added to the models with television showing the strongest effect. Mass media may be helpful in reducing social disparities in HIV/AIDS outcomes.

  3. Heat waves and morbidity: current knowledge and further direction-a comprehensive literature review.

    Science.gov (United States)

    Li, Mengmeng; Gu, Shaohua; Bi, Peng; Yang, Jun; Liu, Qiyong

    2015-05-18

    In the past few decades, several devastating heat wave events have significantly challenged public health. As these events are projected to increase in both severity and frequency in the future, it is important to assess the relationship between heat waves and the health indicators that can be used in the early warning systems to guide the public health response. Yet there is a knowledge gap in the impact of heat waves on morbidity. In this study, a comprehensive review was conducted to assess the relationship between heat waves and different morbidity indicators, and to identify the vulnerable populations. The PubMed and ScienceDirect database were used to retrieve published literature in English from 1985 to 2014 on the relationship between heat waves and morbidity, and the following MeSH terms and keywords were used: heat wave, heat wave, morbidity, hospital admission, hospitalization, emergency call, emergency medical services, and outpatient visit. Thirty-three studies were included in the final analysis. Most studies found a short-term negative health impact of heat waves on morbidity. The elderly, children, and males were more vulnerable during heat waves, and the medical care demand increased for those with existing chronic diseases. Some social factors, such as lower socioeconomic status, can contribute to heat-susceptibility. In terms of study methods and heat wave definitions, there remain inconsistencies and uncertainties. Relevant policies and guidelines need to be developed to protect vulnerable populations. Morbidity indicators should be adopted in heat wave early warning systems in order to guide the effective implementation of public health actions.

  4. How can countries achieve sustainable food supply in 2050: current knowledge and way forward

    Science.gov (United States)

    Kummu, M.; Fader, M.; Gerten, D.; Guillaume, J. H. A.; Jalava, M.; Jägermeyr, J.; Pfister, S.; Porkka, M.; Siebert, S.; Varis, O.

    2016-12-01

    urgent need to integrate these, and other potential measures, together and deepen the knowledge of their combined impact on future sustainable food supply.

  5. Current knowledge and future research perspectives on cassava (Manihot esculenta Crantz) chemical defenses: An agroecological view.

    Science.gov (United States)

    Pinto-Zevallos, Delia M; Pareja, Martín; Ambrogi, Bianca G

    2016-10-01

    Cassava (Manihot esculenta Crantz) is one of the most important staple crops worldwide. It constitutes the major source of carbohydrates for millions of low-income people living in rural areas, as well as a cash crop for smallholders in tropical and sub-tropical regions. The Food and Agriculture Organization of the United Nations predicts that cassava plantations will increase and production systems will intensify in the future, highlighting the need for developing strategies that improve the sustainability of production. Plant chemical defenses hold the potential for developing pest management strategies, as these plant traits can influence the behavior and performance of both pests and beneficial arthropods. Cassava plants are well-defended and produce a number of compounds involved in direct defense, such as cyanogenic glycosides, flavonoid glycosides, and hydroxycoumarins. In addition, volatile organic compounds induced upon herbivory and the secretion of extrafloral nectar act as indirect defense against herbivores by recruiting natural enemies. Here, cassava chemical defenses against pest arthropods are reviewed, with the aim of identifying gaps in our knowledge and areas of research that deserve further investigation for developing sound pest control strategies to improve sustainable production of this crop, and how these defenses can be used to benefit other crops. Cyanogenic content in cassava is also highly toxic to humans, and can cause irreversible health problems even at sub-lethal doses when consumed over prolonged periods. Therefore, the promotion of chemical defense in this crop should not aggravate these problems, and must be accompanied with the education on processing methods that reduce human exposure to cyanide.

  6. Breast Cancer Screening in Women with Learning Disabilities: Current Knowledge and Considerations

    Science.gov (United States)

    Willis, Diane S.; Kennedy, Catriona M.; Kilbride, Lynn

    2008-01-01

    As people with learning disabilities now live longer, they will experience the same age-related illnesses as the general population and cancer is a prime example of this. In women, cancer screening is used to detect early on-set of cancer of the breast and abnormalities of the cervix which might, if left untreated, develop into cancer.…

  7. Breast Cancer Screening in Women with Learning Disabilities: Current Knowledge and Considerations

    Science.gov (United States)

    Willis, Diane S.; Kennedy, Catriona M.; Kilbride, Lynn

    2008-01-01

    As people with learning disabilities now live longer, they will experience the same age-related illnesses as the general population and cancer is a prime example of this. In women, cancer screening is used to detect early on-set of cancer of the breast and abnormalities of the cervix which might, if left untreated, develop into cancer.…

  8. Exploiting prior knowledge in Intelligent Assistants - Combining relational models with hierarchies

    OpenAIRE

    Natarajan, Sriraam; Tadepalli, Prasad; Fern, Alan

    2008-01-01

    Statitsical relational models have been successfully used to model static probabilistic relationships between the entities of the domain. In this talk, we illustrate their use in a dynamic decison-theoretic setting where the task is to assist a user by inferring his intentional structure and taking appropriate assistive actions. We show that the statistical relational models can be used to succintly express the system's prior knowledge about the user's goal-subgoal structure...

  9. College biology students' conceptions related to the nature of biological knowledge: Implications for conceptual change

    Science.gov (United States)

    Ameny, Gloria Millie Apio

    Adequate understanding of the nature of science is a major goal of science education. Understanding of the evolutionary nature of biological knowledge is a means of reinforcing biology students' understanding of the nature of science. It provides students with the philosophical basis, explanatory ideals, and subject matter-specific views of what counts as a scientifically-acceptable biological explanation. This study examined 121 college introductory biology and advanced zoology students for their conceptions related to the nature of biological knowledge. A 60-item Likert-scale questionnaire called the Nature of Biological Knowledge Scale and student interviews were used as complementary research instruments. Firstly, the study showed that 80--100% of college biology students have an adequate understanding of scientific methods, and that a similar percentage of students had learned the theory of evolution by natural selection in their biology courses. Secondly, the study showed that at least 60--80% of the students do not understand the importance of evolution in biological knowledge. Yet the study revealed that a statistically significant positive correlation exist among students' understanding of natural selection, divergent, and convergent evolutionary models. Thirdly, the study showed that about 20--58% of college students hold prescientific conceptions which, in part, are responsible for students' lack of understanding of the nature of biological knowledge. A statistically significant negative correlation was found among students' prescientific conceptions about basis of biological knowledge and nature of change in biological processes, and their understanding of natural selection and evolutionary models. However, the study showed that students' characteristics such as gender, age, major, or years in college have no statistically significant influence on students' conceptions related to the nature of biological knowledge. Only students' depth of biological

  10. Current knowledge and pending challenges in zoonosis caused by Mycobacterium bovis: a review.

    Science.gov (United States)

    Pérez-Lago, Laura; Navarro, Yurena; García-de-Viedma, Darío

    2014-10-01

    Mycobacterium bovis is both the causative agent of bovine tuberculosis (TB) and a zoonotic pathogen. In humans, considerably fewer cases of TB are caused by M. bovis than M. tuberculosis; nevertheless, diagnostic limitations mean that currently available data on prevalence grossly underestimate the true dimension of the problem. The routes of transmission from animals to humans are well known and include direct exposure to infected animals or consumption of contaminated animal products. Application of fingerprinting tools facilitates analysis of the molecular epidemiology of M. bovis in animal-to-human and human-to-human transmission. Apart from cattle and M. bovis, other animal species and members within the M. tuberculosis complex can contribute to the zoonosis. Improvements in diagnostic techniques, application of more advanced discriminatory genotyping tools, and collaboration between veterinary and human health care researchers are key to our understanding of this zoonosis.

  11. An analysis of risk markers in husband to wife violence: the current state of knowledge.

    Science.gov (United States)

    Hotaling, G T; Sugarman, D B

    1986-01-01

    The present review involves the evaluation of 97 potential risk markers of husband to wife violence. Using 52 case-comparison studies as the source of data, markers were divided into four categories: consistent risk, inconsistent risk, consistent nonrisk, and risk markers with insufficient data. Based on this classification, it appears that a number of widely held hypotheses about husband to wife violence have little empirical support. Only witnessing violence in the wife's family of origin was consistently associated with being victimized by violence. Furthermore, it seems that characteristics associated with either the husband-offender or the couple have greater utility for assessing the risk of husband to wife violence than characteristics of the wife-victim. Findings are discussed in terms of the methodological and theoretical implications of current research on this form of adult domestic violence.

  12. [Pathological buying. A review of the current knowledge regarding this condition of behavioral excess].

    Science.gov (United States)

    Müller, A; de Zwaan, M

    2010-04-01

    Compulsive buying is characterized by frequent excessive purchasing of items that are primarily not needed or used. The compulsive buying behavior results in mental, social, financial and often legal problems. Although compulsive buying affects a significant percentage of the general population and has received increasing attention in research, it has largely been ignored in clinical practice. Compulsive buying disorder is currently conceptualized as an"impulse control disorder not otherwise specified". However, the appropriate classification continues to be debated. Compulsive buying is associated with significant psychiatric co-morbidity, especially with depressive, anxiety, obsessive-compulsive, substance use, personality, and other impulse control disorders. Small controlled trials failed to confirm the efficacy of antidepressants in the treatment of compulsive buying disorder, whereas early evidence suggests that cognitive behavioral therapy is helpful in alleviating compulsive buying symptoms. Further research is needed to establish a better understanding of etiology, classification, and treatment strategies.

  13. Chemical pollution in the Arctic and Sub-Arctic marine ecosystems: an overview of current knowledge

    Energy Technology Data Exchange (ETDEWEB)

    Savinova, T.N.; Gabrielsen, G.W.; Falk-Petersen, S.

    1995-02-01

    This report is part of a research project in the framework of the Norwegian-Russian Environmental Cooperation, which was initiated in 1991 to elucidate the present status of environmental contaminants in the highly sensitive Arctic aquatic ecosystem, with special focus on sea birds. Although these ecosystems are the least polluted areas in the world, they are contaminated. The main pathways of contamination into Arctic and sub-Arctic marine ecosystems are atmospheric transport, ocean currents and rivers and in some areas, dumping and ship accidents. A literature survey reveals: (1) there is a lack of data from several trophic levels, (2) previous data are difficult to compare with recent data because of increased quality requirement, (3) not much has been done to investigate the effects of contaminants on the cellular level, at individual or population levels. 389 refs., 7 figs., 32 tabs.

  14. Knowledge of Emergency Medicine Residents in Relation to Prevention of Tetanus

    Directory of Open Access Journals (Sweden)

    Hojjat Derakhshanfar

    2014-03-01

    Full Text Available Introduction: Knowledge of emergency medicine residents about the management of patients suspected of having tetanus favoring wounds is very important due to their responsibility for the treatment of such patients. The aim of the present study was to evaluate this knowledge and making sure of the adequacy of instructions they have received in relation to prevention of tetanus.  Methods: A reliable and reproducible questionnaire was used to evaluate knowledge of all the emergency medicine residents in Imam Hussein Hospital in Tehran, Iran, about conditions favoring tetanus (9 questions and proper interventions in such conditions (12 questions. The questionnaires were completed and scored as poor and good. The Mann-Whitney U test was used to analyze data. Statistical significance was set at P<0.05. Results: In the present study, 73 emergency medicine residents were evaluated (45.2% male. Knowledge of 31 (42.5% residents in relation to conditions favoring tetanus and 41 (56.2% residents in correct therapeutic interventions was in good level. The most frequent incorrect answer was related to diabetic ulcers and wounds in patients with sepsis. There was an increase in scores of conditions favoring tetanus (P<0.001 and correct therapeutic interventions (P=0.001 with an increase in educational years. However, age (P=0.64, gender (P=0.31, job experience (P=0.38 and participation in educational courses (P=0.67 had no effect on the knowledge level of emergency medicine residents. Conclusion: According to the findings of the present study, the knowledge of emergency medicine residents about correct management of patients suspected of tetanus was low, which emphasizes the necessity of providing further instructions on prevention of tetanus in wound management. 

  15. Text mining of cancer-related information: review of current status and future directions.

    Science.gov (United States)

    Spasić, Irena; Livsey, Jacqueline; Keane, John A; Nenadić, Goran

    2014-09-01

    This paper reviews the research literature on text mining (TM) with the aim to find out (1) which cancer domains have been the subject of TM efforts, (2) which knowledge resources can support TM of cancer-related information and (3) to what extent systems that rely on knowledge and computational methods can convert text data into useful clinical information. These questions were used to determine the current state of the art in this particular strand of TM and suggest future directions in TM development to support cancer research. A review of the research on TM of cancer-related information was carried out. A literature search was conducted on the Medline database as well as IEEE Xplore and ACM digital libraries to address the interdisciplinary nature of such research. The search results were supplemented with the literature identified through Google Scholar. A range of studies have proven the feasibility of TM for extracting structured information from clinical narratives such as those found in pathology or radiology reports. In this article, we provide a critical overview of the current state of the art for TM related to cancer. The review highlighted a strong bias towards symbolic methods, e.g. named entity recognition (NER) based on dictionary lookup and information extraction (IE) relying on pattern matching. The F-measure of NER ranges between 80% and 90%, while that of IE for simple tasks is in the high 90s. To further improve the performance, TM approaches need to deal effectively with idiosyncrasies of the clinical sublanguage such as non-standard abbreviations as well as a high degree of spelling and grammatical errors. This requires a shift from rule-based methods to machine learning following the success of similar trends in biological applications of TM. Machine learning approaches require large training datasets, but clinical narratives are not readily available for TM research due to privacy and confidentiality concerns. This issue remains the main

  16. Discovering the meaning of monoclonal gammopathy of undetermined significance: current knowledge, future challenges.

    Science.gov (United States)

    Palladino, C; Bruno, B; Boccadoro, M

    2014-01-01

    Monoclonal gammopathy of undetermined significance (MGUS) is a non malignant plasma cell disorder with a relatively low risk of progression to Multiple Myeloma (MM) and to related Plasma cells disordes (lymphoplasmacellular neoplasms, Waldenstrom Macroglobulinemia or light chain amyloidosis). It is a quite common finding, especially in the population above the age of 50 and it can also present in association with many non malignant conditions. Differential diagnosis of symptomatic and asymptomatic forms is the determinant for starting therapy. Over the last few years many advances in the understanding of the biology of MGUS, together with large epidemiological studies, allowed to define risk models to estimate the risk of progression to MM according to MGUS isotype and, more recently, to peculiar flow cytometry findings. The goal of many recent studies aims at evaluating individual patients and their overall risk of progression, the detection of early signs of progression and the development of timely treatment strategies.

  17. A synthesis of current knowledge on forests and carbon storage in the United States.

    Science.gov (United States)

    McKinley, Duncan C; Ryan, Michael G; Birdsey, Richard A; Giardina, Christian P; Harmon, Mark E; Heath, Linda S; Houghton, Richard A; Jackson, Robert B; Morrison, James F; Murray, Brian C; Patakl, Diane E; Skog, Kenneth E

    2011-09-01

    Using forests to mitigate climate change has gained much interest in science and policy discussions. We examine the evidence for carbon benefits, environmental and monetary costs, risks and trade-offs for a variety of activities in three general strategies: (1) land use change to increase forest area (afforestation) and avoid deforestation; (2) carbon management in existing forests; and (3) the use of wood as biomass energy, in place of other building materials, or in wood products for carbon storage. We found that many strategies can increase forest sector carbon mitigation above the current 162-256 Tg C/yr, and that many strategies have co-benefits such as biodiversity, water, and economic opportunities. Each strategy also has trade-offs, risks, and uncertainties including possible leakage, permanence, disturbances, and climate change effects. Because approximately 60% of the carbon lost through deforestation and harvesting from 1700 to 1935 has not yet been recovered and because some strategies store carbon in forest products or use biomass energy, the biological potential for forest sector carbon mitigation is large. Several studies suggest that using these strategies could offset as much as 10-20% of current U.S. fossil fuel emissions. To obtain such large offsets in the United States would require a combination of afforesting up to one-third of cropland or pastureland, using the equivalent of about one-half of the gross annual forest growth for biomass energy, or implementing more intensive management to increase forest growth on one-third of forestland. Such large offsets would require substantial trade-offs, such as lower agricultural production and non-carbon ecosystem services from forests. The effectiveness of activities could be diluted by negative leakage effects and increasing disturbance regimes. Because forest carbon loss contributes to increasing climate risk and because climate change may impede regeneration following disturbance, avoiding

  18. Air travel and radiation risks - review of current knowledge; Flugreisen und Strahlenrisiken - eine aktuelle Uebersicht

    Energy Technology Data Exchange (ETDEWEB)

    Zeeb, H. [Bielefeld Univ. (Germany). Fakultaet fuer Gesundheitswissenschaften; Blettner, M. [Mainz Univ. (Germany). Inst. fuer Medizinische Biometrie, Epidemiologie und Informatik

    2004-07-01

    Aircrew and passengers are exposed to cosmic radiation, in particular when travelling routes close to the poles and in high altitudes. The paper reviews current radiation measurement and estimation approaches as well as the actual level of cosmic radiation that personnel and travellers receive and summarizes the available epidemiological evidence on health effects of cosmic radiation. On average, German aircrew is exposed to les than 5 mSv per annum, and even frequent travellers only rarely reach values above 1 mSv/year. Cohort studies among aircrew have found very little evidence for an increased incidence or mortality of radiation-associated cancers. Only malignant melanoma rates have consistently found to be increased among male aircrew. Socioeconomic and reproductive aspects are likely to contribute to the slightly elevated breast cancer risk of female aircrew. Cytogenetic studies have not yielded consistent results. Based on these data overall risk increases for cancer among occupationally exposed aircrew appear unlikely. This also applies to air travellers who are usually exposed to much lower radiation levels. Occasional air travel during pregnancy does not pose a significant radiation risk, but further considerations apply in this situation. The currently available studies are limited with regard to methodological issues and case numbers so that a continuation of cohort studies in several European countries is being planned. (orig.) [German] Sowohl Flugpersonal wie Flugreisende sind kosmischer Strahlung ausgesetzt, insbesondere wenn sie auf polnahen Routen und in grossen Flughoehen reisen. Die vorliegende Arbeit gibt einen aktuellen Ueberblick ueber Mess- und Schaetzverfahren sowie das Ausmass der kosmischen Strahlenexposition und fasst die derzeit bekannte epidemiologische Evidenz zu gesundheitlichen Aspekten der kosmischen Strahlenexposition zusammen. Die durchschnittliche jaehrliche Strahlenexposition beruflich exponierten Flugpersonals liegt in

  19. Microbiome and nutrition in autism spectrum disorder: current knowledge and research needs.

    Science.gov (United States)

    Berding, Kirsten; Donovan, Sharon M

    2016-12-01

    Autism spectrum disorder (ASD) is the fastest growing neurodevelopmental disorder in the United States. Besides genetic risks, environmental factors have been suggested to contribute to the increase in ASD diagnosis over the past decade. Several studies have reported abnormalities in microbiota composition and differences in microbial metabolites in children with ASD. Gastrointestinal discomfort is commonly reported in children with ASD. Additionally, food selectivity and picky eating patterns are commonly reported. A number of mechanisms underlying the interaction between nutrition, the gut microbiota, and ASD symptoms via the microbiota-gut-brain axis have been proposed, including immune, hormonal, or neuronal pathways. Here, the current evidence base regarding the gut environment and nutritional status of children with ASD is reviewed. Potential underlying mechanisms of the microbiota-gut-brain axis in ASD and the interplay between nutrition, microbiota, and ASD symptoms are also reviewed. Future studies investigating the microbiota in the context of dietary intake are needed to increase understanding of the interplay between diet and the gut microbiota in ASD and to identify potential dietary, probiotic, or prebiotic intervention strategies.

  20. Bacterial Diseases of Bananas and Enset: Current State of Knowledge and Integrated Approaches Toward Sustainable Management

    Directory of Open Access Journals (Sweden)

    Guy Blomme

    2017-07-01

    Full Text Available Bacterial diseases of bananas and enset have not received, until recently, an equal amount of attention compared to other major threats to banana production such as the fungal diseases black leaf streak (Mycosphaerella fijiensis and Fusarium wilt (Fusarium oxysporum f. sp. cubense. However, bacteria cause significant impacts on bananas globally and management practices are not always well known or adopted by farmers. Bacterial diseases in bananas and enset can be divided into three groups: (1 Ralstonia-associated diseases (Moko/Bugtok disease caused by Ralstonia solanacearum and banana blood disease caused by R. syzygii subsp. celebesensis; (2 Xanthomonas wilt of banana and enset, caused by Xanthomonas campestris pv. musacearum and (3 Erwinia-associated diseases (bacterial head rot or tip-over disease Erwinia carotovora ssp. carotovora and E. chrysanthemi, bacterial rhizome and pseudostem wet rot (Dickeya paradisiaca formerly E. chrysanthemi pv. paradisiaca. Other bacterial diseases of less widespread importance include: bacterial wilt of abaca, Javanese vascular wilt and bacterial fingertip rot (probably caused by Ralstonia spp., unconfirmed. This review describes global distribution, symptoms, pathogenic diversity, epidemiology and the state of the art for sustainable disease management of the major bacterial wilts currently affecting banana and enset.

  1. Biotherapy in Inflammatory Diseases of the CNS: Current Knowledge and Applications.

    Science.gov (United States)

    Collongues, Nicolas; Michel, Laure; de Seze, Jérôme

    2017-05-01

    Biotherapy represents an innovative therapeutic approach that includes immunotherapy (vaccines, apheresis, and antibodies); gene therapy; and stem cell transplants. Their development helps to cross the bridge from bench to bedside and brings new hope of a cure for severe diseases in different fields of medicine. In neurology, a growing range of applications is being developed for these medications. Valuable results are now available in the field of autoimmunity, neuro-oncology, paraneoplastic manifestations, and neurodegenerative disorders. In this review, we examine the current and future applications of biotherapy in the field of inflammation of the central nervous system. We demonstrate its contribution in clinical practice, where it has enabled a significant level of effectiveness to be achieved. Indeed, the efficacy of these new biodrugs provides a solution for patients refractory to standard therapies, such as intravenous immunoglobulins in limbic encephalitis, plasma exchanges in neuromyelitis optica and anti-CD20 monoclonal antibodies in multiple sclerosis. They also mark the first steps towards individualized medicine.

  2. Current knowledge on tumour induction by computed tomography should be carefully used

    Energy Technology Data Exchange (ETDEWEB)

    Candela-Juan, Cristian [La Fe University and Polytechnic Hospital, Radioprotection Department, Valencia (Spain); Montoro, Alegria; Villaescusa, Juan Ignacio [La Fe University and Polytechnic Hospital, Radioprotection Department, Valencia (Spain); IIS La Fe, Biomedical Imaging Research Group GIBI230, Valencia (Spain); Ruiz-Martinez, Enrique; Marti-Bonmati, Luis [IIS La Fe, Biomedical Imaging Research Group GIBI230, Valencia (Spain); La Fe University and Polytechnic Hospital, Department of Radiology, Valencia (Spain)

    2014-03-15

    Risks associated to ionising radiation from medical imaging techniques have focused the attention of the medical society and general population. This risk is aimed to determine the probability that a tumour is induced as a result of a computed tomography (CT) examination since it makes nowadays the biggest contribution to the collective dose. Several models of cancer induction have been reported in the literature, with diametrically different implications. This article reviews those models, focusing on the ones used by the scientific community to estimate CT detriments. Current estimates of the probability that a CT examination induces cancer are reported, highlighting its low magnitude (near the background level) and large sources of uncertainty. From this objective review, it is concluded that epidemiological data with more accurate dosimetric estimates are needed. Prediction of the number of tumours that will be induced in population exposed to ionising radiation should be avoided or, if given, it should be accompanied by a realistic evaluation of its uncertainty and of the advantages of CTs. Otherwise they may have a negative impact in both the medical community and the patients. Reducing doses even more is not justified if that compromises clinical image quality in a necessary investigation. (orig.)

  3. Social stress as a cause of diseases in farm animals: Current knowledge and future directions.

    Science.gov (United States)

    Proudfoot, Kathryn; Habing, Gregory

    2015-10-01

    Over the past 50 years, biomedical research has established a strong linkage between psychosocial stress and disease risk in humans, which has transformed the understanding of stress and the role it plays in human lives. This research has led to personalized medicine where a reduction in daily life stress is a main goal for many people with debilitating illnesses. This review describes the supporting evidence that social stress also plays a critical role in farm animal disease prevention, and may be a mediator by which common management practices can increase disease risk. There is evidence that social factors, including deprivation of social contact ('social isolation'), reducing space allowance ('crowding') and disturbing social order ('social instability') trigger physiological and behavioral indicators of stress in livestock. Less research exists, however, linking management practices that trigger social stress with higher disease risk. Suggestions are offered for future research opportunities, and practical, evidence-based recommendations are made for reducing the negative effects of social isolation, instability and crowding. The current evidence that social factors contribute to disease risk in farm animals is not as convincing as the human literature, but remains a promising and important area for future research. Copyright © 2015 Elsevier Ltd. All rights reserved.

  4. Adjuvants and immunostimulants in fish vaccines: current knowledge and future perspectives.

    Science.gov (United States)

    Tafalla, Carolina; Bøgwald, Jarl; Dalmo, Roy A

    2013-12-01

    Vaccination is the most adequate method to control infectious diseases that threaten the aquaculture industry worldwide. Unfortunately, vaccines are usually not able to confer protection on their own; especially those vaccines based on recombinant antigens or inactivated pathogens. Therefore, the use of adjuvants or immunostimulants is often necessary to increase the vaccine efficacy. Traditional adjuvants such as mineral oils are routinely used in different commercial bacterial vaccines available for fish; however, important side effects may occur with this type of adjuvants. A search for alternative molecules or certain combinations of them as adjuvants is desirable in order to increase animal welfare without reducing protection levels. Especially, combinations that may target specific cell responses and thus a specific pathogen, with no or minor side effects, should be explored. Despite this, the oil adjuvants currently used are quite friendlier with respect to side effects compared with the oil adjuvants previously used. The great lack of fish antiviral vaccines also evidences the importance of identifying optimal combinations of a vaccination strategy with the use of a targeting adjuvant, especially for the promising fish antiviral DNA vaccines. In this review, we summarise previous studies performed with both traditional adjuvants as well as the most promising new generation adjuvants such as ligands for Toll receptors or different cytokines, focussing mostly on their protective efficacies, and also on what is known concerning their effects on the fish immune system when delivered in vivo.

  5. The current state of knowledge about shatter cones: Introduction to the special issue

    Science.gov (United States)

    Baratoux, David; Reimold, Wolf Uwe

    2016-08-01

    Shatter cones are a fracture phenomenon that is exclusively associated with shock metamorphism and has also been produced in the laboratory in several shock experiments. The occurrence of shatter cones is the only accepted meso- to macroscopic recognition criterion for impact structures. Shatter cones exhibit a number of geometric characteristics (orientation, apical angles, striation angles, sizes) that can be best described as varied, from case to case. Possible links between geometric properties with impact or crater parameters have remained controversial and the lack of understanding of the mechanism of formation of shatter cones does not offer a physical framework to discuss or understand them. A database of shatter cone occurrences has been produced for this introduction paper to the special issue of Meteoritics and Planetary Science on shatter cones. Distribution of shatter cones with respect to crater size and lithology suggests that shatter cones do not occur in impact craters less than a few kilometers in diameter, with a few, currently questionable exceptions. All pertinent hypotheses of formation are presented and discussed. Several may be discarded in light of the most recent observations. The branching fracture mechanism and the interference models proposed, respectively, by Sagy et al. (2002) and Baratoux and Melosh (2003) require further evaluation. New observations, experiments, or theoretical considerations presented in this special issue promise an important step forward, based on a renewed effort to resolve the enigmatic origin of these important features.

  6. IGF-I abuse in sport: current knowledge and future prospects for detection.

    Science.gov (United States)

    Guha, Nishan; Sönksen, Peter H; Holt, Richard I G

    2009-08-01

    As the tests for detecting growth hormone (GH) abuse develop further, it is likely that athletes will turn to doping with insulin-like growth factor-I (IGF-I). IGF-I mediates many of the anabolic actions of growth hormone. It stimulates muscle protein synthesis, promotes glycogen storage and enhances lipolysis, all of which make IGF-I attractive as a potential performance-enhancing agent. Pharmaceutical companies have developed commercial preparations of recombinant human IGF-I (rhIGF-I) for use in disorders of growth. The increased availability of rhIGF-I increases the opportunity for athletes to acquire supplies of the drug on the black market. The long-term effects of IGF-I administration are currently unknown but it is likely that these will be similar to the adverse effects of chronic GH abuse. The detection of IGF-I abuse is a challenge for anti-doping organisations. Research has commenced into the development of a test for IGF-I abuse based on the measurement of markers of GH action. Simultaneously, the effects of rhIGF-I on physical fitness, body composition and substrate utilisation in healthy volunteers are being investigated.

  7. Current state of knowledge on the traditional uses, phytochemistry, and pharmacology of the genus Hymenaea.

    Science.gov (United States)

    Boniface, Pone Kamdem; Baptista Ferreira, Sabrina; Roland Kaiser, Carlos

    2017-07-12

    Plants of the genus Hymenaea (Fabaceae) are used in South American and Asian traditional medicines to treat a multitude of disorders, like cough, diarrhea, dysentery, intestinal colic, pulmonary weakness, asthma, anemia, sore throat, and for the treatment of kidney problems, viral related disorders, chronic cystitis, bronchitis, and bladder infections. Some Hymenaea species are also used as vermifuge, and for the treatment of arthritis, and inflammation conditions. This review deals with updated information on the traditional uses, phytochemistry and pharmacology of ethnomedicinally important Hymenaea species in order to provide an input for the future research prospects. Literature available in various recognized databases including Google Scholar, PubMed, SciFinder, Scopus, Springer, Wiley, ACS, Scielo and Web of Science, as well as from theses, dissertations, books, reports, and other relevant websites (www.theplantlist.org), are surveyed, analysed, and included in this review. Herein, the literature related to chemical constituents and pharmacological activities were searched in November 2016. The literature provided information on ethnopharmacological uses of the South American and African species of the genus Hymenaea (e.g., H. courbaril, H. stigonocarpa, H. onblogifolia, H. martiana, H. parvifolia (South America) and H. verrucosa (African species)) for the treatment of multi-factorial diseases. From these plant species, more than 130 compounds, including fatty acids, flavonoids, terpenoids and steroids, phthalides, phenolic acids, procyanidins and coumarins were identified. Experimental evidences confirmed that the Hymenaea spp. could be used in treating inflammatory disorders, asthma, diarrhea, and some microbial infections. However, reports on the toxicity of Hymenaea species remain scarce. Plants of this genus have offered bioactive samples, both from crude extracts and pure compounds, thus substantiating their effectiveness in traditional medicine

  8. Knowledge and attitudes of nurses towards alcohol and related problems: the impact of an educational intervention

    Directory of Open Access Journals (Sweden)

    Janaina Soares

    2013-10-01

    Full Text Available An exploratory study of quasi-experimental approach that aimed to verify the impact of an educational intervention on attitudes and knowledge of nurses towards alcohol use and associated problems. The sample included 185 nurses, divided into two groups: 84 submitted to a training course and formed the experimental group. Data were collected through a knowledge survey and an attitude scale. The attitudes of the participants of both groups were positive. There were no significant differences between groups in relation to knowledge. The strongest predictors of positive attitudes were possessed preparation to act with chemical dependents (OR = 2.18, "have received increased workload during graduation on the theme, 'alcohol and other drugs'" (OR = 1.70, and "completed graduate school" (OR = 2.59. The educational intervention had a positive impact on the attitudes of nurses towards alcoholics, work and interpersonal relationships with such clientele.

  9. Association of blood pressure with sodium-related knowledge and behaviors in adults with hypertension.

    Science.gov (United States)

    Westrick, Salisa C; Garza, Kimberly B; Stevenson, T Lynn; Oliver, Wesley D

    2014-01-01

    OBJECTIVES To describe sodium-related knowledge and self-reported behaviors in adults with hypertension and assess the association between knowledge and behaviors and blood pressure levels in this population. METHODS Using convenience sampling of patients with hypertension, an oral cross-sectional survey was administered by student pharmacists in 45 community pharmacies in Alabama and Florida in May to July 2012. After survey questions were administered, patients' blood pressures were measured. Data were tested for significance at alpha high blood pressure (91.1%) and stroke (78.0%). A small percentage of patients reported that they always look for sodium content on food products (15.0%) and always buy low-sodium products (10.6%). Patients with lower knowledge scores (B = -0.01, P food and did not always look for sodium content on nutritional labels. Pharmacists should address dietary salt when interacting with patients with hypertension.

  10. Adherence, knowledge, and difficulties related to pharmacological treatment for people with schizophrenia

    Directory of Open Access Journals (Sweden)

    Adriana Inocenti Miasso

    2015-06-01

    Full Text Available This study aimed to verify the adherence and knowledge of people with schizophrenia as regards their prescribed pharmacotherapy, and to identify the difficulties related to the monitoring of drug therapy. It was a retrospective, cross-sectional, and descriptive study conducted in an outpatient psychiatry clinic, with 21 patients with schizophrenia, through chart review and a semi-structured interview. The data were analyzed using descriptive statistics and content analysis showing that, although 76.2% of patients adhere to treatment, most were unaware of the treatment regimen. Limitations in the administration of drugs, troublesome due to side effects and conflicts regarding the need for the drugs, were the difficulties pointed out by the study participants. The contradiction between high adherence and lack of knowledge about prescriptions reveal that promoting treatment adherence and patient safety requires interventions that address the skills and knowledge of the individual, as well as the support available for the administration of prescription drugs.

  11. DIFFERENCES IN GENERAL POPULATION ON KNOWLEDGE, ATTITUDES AND BEHAVIOUR RELATED TO MENTAL HEALTH STIGMA

    Directory of Open Access Journals (Sweden)

    Ana María Moreno Herrero

    2014-05-01

    Full Text Available Stigma in mental health is studied in a sample of 152 subjects of Almería city population with the aim of designing specific anti-stigma campaigns. For this, Stigma is operatized in three constructs: Knowledge, Attitudes and Behaviour, using MAKS, CAMI and RIBS scales for these. Results show that the younger group, under thirty-five years old are less knowledgeable about mental health related to stigma, showing a significant difference (p< .05. Moreover, we found significant differences in gender regarding the intention of stigmatizing behaviour (p=.049 as well as attitudes (p= .006 where men have more stigmatizing behaviour and attitudes than women. These results together with those that show a significant correlation between knowledge and behaviour, as well as between attitudes and behaviour will be used as a guide to design interventions aimed to reduce stigma in mental health.

  12. 基于Concept-Relation模型的知识联通%Based-Concept-Relation-Model Knowledge Interconnection

    Institute of Scientific and Technical Information of China (English)

    雷玉霞; 眭跃飞

    2002-01-01

    It is necessary for computer to have a large knowledge base, while a lot of practice has proved that computer more needs broad knowledge interconnection in order to really realize intelligence. MindNet has dealt with the semantic path, which is kind of word-interconnection. In National Knowledge Infrastructure (NKI), we regard a closed-semantic statement as a whole knowledge unit, and discuss the interconnectivity between two statements.Knowledge interconnection is necessary in the view of knowledge engineering, and is feasible in the view of cognition and semantics. In this paper, we firstly introduce concept-relation-model, which is a suitable knowledge representation model for knowledge interconnection, and then we discuss knowledge interconnection based on the properties of relations in CR-model.

  13. [Relationships between diabetes mellitus and periodontal disease: current knowledges and therapeutic prospects].

    Science.gov (United States)

    Garofalo, G S

    2008-01-01

    Diabetes mellitus is a disorder of the endocrine system. An important pathology of dental interest to which the diabetic patient can go encounter, especially if not controlled from the metabolic point of view, is the periodontal disease. The aim of this review is to illustrate the relation between diabetes mellitus and periodontal disease estimating the several therapeutic options on hand in the clinical daily practice. Many studies show an important association between diabetes and the pathogenesis of periodontal disease. Vascular changes caused by hyper-glycemia are associated to the development of periodontal pathogens species. Moreover, diabetics show an exacerbate host response with hyperproduction of inflammatory mediators and polymorphonuclear dysfunction. Diabetics with good metabolic control and patients with good oral hygiene show a reduced risk of periodontitis. In conclusion, diabetes mellitus (of type 1 and type 2) is an important risk factor for periodontitis. Diabetes mellitus determines changes in bacterial population and production of inflammatory mediators, and reduces the efficacy of the host response. Good controlled diabetes do not cause a major risk of periodontitis and improve the results of the periodontal initial therapy and of the eventual surgical therapy. Moreover, periodontal therapy may reduce the request of insulin in diabetics. It is reasonable a reciprocal relation between diabetes and periodontal disease.

  14. [Epidemiological investigation of macrosomia-related knowledge awareness among pregnant women in Zhejiang province].

    Science.gov (United States)

    Yu, Sha; Guo, Changman; Xi, Haiyang; Zhu, Lihua; Ma, Shanshan; Yang, Xinjun

    2015-07-01

    To understand the awareness rate of macrosomia related knowledge and influencing factors among pregnant women in Zhejiang province and provide evidence for the improvement of pre-gestational and prenatal care. A face to face questionnaire survey was conducted among 1 512 pregnant women selected through multistage cluster random sampling from 20 counties (district) in Zhejiang. Macrosomia-related awareness and related factors were analyzed. A total of 1 494 valid questionnaires were analyzed, the awareness rate was 40.7% for macrosomia diagnostic criteria (95% CI: 38.2%-43.2%), 55.0% for the cause of macrosomia (95% CI: 52.4%-57.6%) and 62.4% for prevention related knowledge (95% CI: 59.9%-64.9%) and the awareness rate of both the cause and the prevention related knowledge was 49.0% (95% CI: 46.4%-51.6%). Multivariate logistic regression analysis showed that the third trimester of pregnancy (OR = 1.906, 95% CI: 1.128-3.221), urban residence (OR = 1.335, 95% CI: 1.014-1.756), educational level of junior college (OR = 2.474, 95% CI: 1.635-3.744) and educational level of regular college or above (OR = 2.072, 95% CI: 1.338-3.209), receiving health education about health pregnancy (OR = 1.936, 95% CI: 1.509-2.484) and self-learning about the knowledge of health pregnancy (OR = 2.065, 95%CI: 1.338-3.189) were the influencing factors to the awareness rate of macrosomia diagnostic criteria and prevention related knowledge of macrosomia among pregnant women. The awareness rate of the cause and prevention related knowledge of macrosomia was higher in older age group (OR = 2.103, 95% CI: 1.330-3.323). Among the pregnant women in Zhejiang, the awareness rate of macrosomia diagnostic criteria was less than 50%. Therefore, it was necessary to strengthen the health education during pre-gestational and gestational periods among reproductive women, especially the education about pregnancy health in rural area.

  15. Metacognitive Knowledge in Relation to Inquiry Skills and Knowledge Acquisition Within a Computer-Supported Inquiry Learning Environment

    Directory of Open Access Journals (Sweden)

    Zrinka Ristić Dedić

    2014-04-01

    Full Text Available The study examines two components of metacognitive knowledge in the context of inquiry learning: metatask and metastrategic. Existing work on the topic has shown that adolescents often lacked metacognitive understanding necessary for optimal inquiry learning (Keselman & Kuhn, 2002; Kuhn, 2002a; Kuhn, Black, Keselman, & Kaplan, 2000, but demonstrated that engagement with inquiry tasks may improve it (Keselman, 2003; Kuhn & Pearsall, 1998.The aim of the study is to investigate the gains in metacognitive knowledge that occur as a result of repeated engagement with an inquiry learning task, and to examine the relationship between metacognitive knowledge and performance on the task.The participants were 34 eighth grade pupils, who participated in a self-directed experimentation task using the FILE programme (Hulshof, Wilhelm, Beishuizen, & van Rijn, 2005. The task required pupils to design and conduct experiments and to make inferences regarding the causal structure of a multivariable system. Pupils participated in four learning sessions over the course of one month. Metacognitive knowledge was assessed by the questionnaire before and after working in FILE.The results indicate that pupils improved in metacognitive knowledge following engagement with the task. However, many pupils showed insufficient metacognitive knowledge in the post-test and failed to apply newly achieved knowledge to the transfer task. Pupils who attained a higher level of metacognitive knowledge were more successful on the task than pupils who did not improve on metacognitive knowledge. A particular level of metacognitive understanding is a necessary, but not sufficient condition for successful performance on the task.

  16. Current knowledge and importance of dGEMRIC techniques in diagnosis of hip joint diseases

    Energy Technology Data Exchange (ETDEWEB)

    Zilkens, Christoph; Krauspe, Ruediger; Bittersohl, Bernd [University of Duesseldorf, Medical Faculty, Department of Orthopedic Surgery, Duesseldorf (Germany); Tiderius, Carl Johann [Lund University Hospital, Department of Orthopedic Surgery, Lund (Sweden)

    2015-08-15

    Accurate assessment of early hip joint cartilage alterations may help optimize patient selection and follow-up of hip joint preservation surgery. Delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) is sensitive to the glycosaminoglycan content in cartilage that is lost early in the development of osteoarthritis (OA). Hence, the dGEMRIC technique holds promise for the development of new diagnostic and therapeutic procedures. However, because of the location of the hip joint deep within the body and due to the fairly thin cartilage layers that require high spatial resolution, the diagnosis of early hip joint cartilage alterations may be problematic. The purpose of this review is to outline the current status of dGEMRIC in the assessment of hip joint cartilage. A literature search was performed with PubMed, using the terms ''cartilage, osteoarthritis, hip joint, MRI, and dGEMRIC'', considering all levels of studies. This review revealed that dGEMRIC can be reliably used in the evaluation of early stage cartilage pathology in various hip joint disorders. Modifications in the technique, such as the operation of three-dimensional imaging and dGEMRIC after intra-articular contrast medium administration, have expanded the range of application. Notably, the studies differ considerably in patient selection and technical prerequisites. Furthermore, there is a need for multicenter prospective studies with the required technical conditions in place to establish outcome based dGEMRIC data to obtain, in conjunction with clinical data, reliable threshold values for normal and abnormal cartilage, and for hips that may benefit from conservative or surgical treatment. (orig.)

  17. Legal rights to safe abortion: knowledge and attitude of women in North-West Ethiopia toward the current Ethiopian abortion law.

    Science.gov (United States)

    Muzeyen, R; Ayichiluhm, M; Manyazewal, T

    2017-07-01

    To assess women's knowledge and attitude toward Ethiopian current abortion law. A quantitative, community-based cross-sectional survey. Women of reproductive age in three selected lower districts in Bahir Dar, North-West Ethiopia, were included. Multi-stage simple random sampling and simple random sampling were used to select the districts and respondents, respectively. Data were collected using a structured questionnaire comprising questions related to knowledge and attitude toward legal status of abortion and cases where abortion is currently allowed by law in Ethiopia. Descriptive statistics were used to summarize the data and multivariable logistic regression computed to assess the magnitude and significance of associations. Of 845 eligible women selected, 774 (92%) consented to participate and completed the interview. A total of 512 (66%) women were aware of the legal status of the Ethiopian abortion law and their primary sources of information were electronic media such as television and radio (43%) followed by healthcare providers (38.7%). Among women with awareness of the law, 293 (57.2%) were poor in knowledge, 188 (36.7%) fairly knowledgeable, and 31 (6.1%) good in knowledge about the cases where abortion is allowed by law. Of the total 774 women included, 438 (56.5%) hold liberal and 336 (43.5%) conservative attitude toward legalization of abortion. In the multivariable logistic regression, age had a significant association with knowledge, whereas occupation had a significant association with attitude toward the law. Women who had poor knowledge toward the law were more likely to have conservative attitude toward the law (adjusted odds ratio, 0.40; 95% confidence interval, 0.23-0.61). Though the Ethiopian criminal code legalized abortion under certain circumstances since 2005, a significant number of women knew little about the law and several protested legalization of abortion. Countries such as Ethiopia with high maternal mortality records need to lift

  18. Thiomersal-containing vaccines - a review of the current state of knowledge.

    Science.gov (United States)

    Gołoś, Aleksandra; Lutyńska, Anna

    2015-01-01

    Thiomersal is an organomercury compound known for its antiseptic and antifungal properties and used as an antibacterial agent in pharmaceutical products, including vaccines and other injectable biological products. In recent years, concerns about the possible link between immunization with thiomersal-containing vaccines and autism development have grown. Many case-control and cohort studies have been conducted on a number of populations, and none of them have confirmed the hypothetical relation between thiomersal and increased risk of autism spectrum disorders (ASDs) development. It is also confirmed by the fact, that since 1999, number of thiomersal-containing vaccines used worldwide is decreasing year by year, while the prevalence of ASDs cases is rising. There are no contraindications to the use of vaccines with thiomersal in infants, children and non-pregnant women. The risk of serious complications associated with the development of diseases in unvaccinated individuals far outweighs the potential risk of adverse consequences associated with immunization with thiomersal-containing vaccines.

  19. Protection of Renal Tubular Cells by Antioxidants: Current Knowledge and New Trends

    Directory of Open Access Journals (Sweden)

    Azar Baradaran

    2015-01-01

    Full Text Available Acute renal damage mainly develops following toxic or ischemic insults and is defined as acute. These damages have largely been attributed to oxidative stress. Recently much attention has been directed toward decreased renal tubular cell regeneration during tubular cell injury. Antioxidants have recently been the focus of researchers and scientists for prevention and treatment of various oxidative stress-related conditions, including renal toxicities. Although free radicals are known to contribute in kidney injury and abundant researches, particularly laboratory trials, have shown the beneficial effects of antioxidants against these complications, long term clinical trials do not uniformly confirm this matter,especially for single antioxidant consumption such as vitamin C. The aim of this paper is to discuss the possible explanation of this matter.

  20. Ecological economics of soil erosion: a review of the current state of knowledge.

    Science.gov (United States)

    Adhikari, Bhim; Nadella, Karthik

    2011-02-01

    The economics of land degradation has received relatively little attention until recent years. Although a number of studies have undertaken valuation of ecosystem services ranging from the global to the micro level, and quite a few studies have attempted to quantify the costs of soil erosion, studies that address the full costs of land degradation are still scarce. In this review, we attempt to analyze different land resource modeling and valuation techniques applied in earlier research and the type of data used in these analyses, and to assess their utility for different forms of land resource and management appraisal. We also report on the strengths and weaknesses of different valuation techniques used in studies on the economics of soil erosion, and the relevance of these valuation techniques. We make a case for the need for more appropriate models that can make the analysis more robust in estimating the economic costs of land degradation while recognizing the spatial heterogeneity in biophysical and economic conditions.

  1. Stress and breast cancer: a systematic update on the current knowledge

    DEFF Research Database (Denmark)

    Nielsen, Naja Rod; Grønbaek, Morten

    2006-01-01

    A vast body of research has been carried out to examine the relationship between psychological stress and the risk of breast cancer. Previous reviews on this issue have mainly focused on stressful life events and have included both prospective and retrospective studies. The results from...... these reviews have revealed conflicting data. We evaluate whether stressful life events, work-related stress, or perceived global stress are differentially associated with breast cancer incidence and breast cancer relapse in prospective studies. Systematic and explicit methods were used to identify, select......, and critically appraise relevant studies. The substantial variability in the manner in which stress was conceptualized and measured did not allow for the calculation of a quantitative summary estimate for the association between stress and breast cancer. Despite the heterogeneity in the results obtained...

  2. The neuroendocrine regulation of food intake in fish: a review of current knowledge

    Directory of Open Access Journals (Sweden)

    Helene Volkoff

    2016-11-01

    Full Text Available Fish are the most diversified group of vertebrates and, although progress has been made in the past years, only relatively few fish species have been examined to date, with regards to the endocrine regulation of feeding in fish. In fish, as in mammals, feeding behavior is ultimately regulated by central effectors within feeding centers of the brain, which receive and process information from endocrine signals from both brain and peripheral tissues. Although basic endocrine mechanisms regulating feeding appear to be conserved among vertebrates, major physiological differences between fish and mammals and the diversity of fish, in particular in regard to feeding habits, digestive tract anatomy and physiology, suggest the existence of fish- and species-specific regulating mechanisms. This review provides an overview of hormones known to regulate food intake in fish, emphasizing on major hormones and the main fish groups studied to date.

  3. The Neuroendocrine Regulation of Food Intake in Fish: A Review of Current Knowledge.

    Science.gov (United States)

    Volkoff, Helene

    2016-01-01

    Fish are the most diversified group of vertebrates and, although progress has been made in the past years, only relatively few fish species have been examined to date, with regards to the endocrine regulation of feeding in fish. In fish, as in mammals, feeding behavior is ultimately regulated by central effectors within feeding centers of the brain, which receive and process information from endocrine signals from both brain and peripheral tissues. Although basic endocrine mechanisms regulating feeding appear to be conserved among vertebrates, major physiological differences between fish and mammals and the diversity of fish, in particular in regard to feeding habits, digestive tract anatomy and physiology, suggest the existence of fish- and species-specific regulating mechanisms. This review provides an overview of hormones known to regulate food intake in fish, emphasizing on major hormones and the main fish groups studied to date.

  4. Current Public Knowledge Pertaining to Traumatic Brain Injury: Influence of Demographic Factors, Social Trends, and Sport Concussion Experience on the Understanding of Traumatic Brain Injury Sequelae.

    Science.gov (United States)

    Merz, Zachary C; Van Patten, Ryan; Lace, John

    2017-03-01

    The current study aimed to assess current broad traumatic brain injury (TBI)-related knowledge in the general public, as well as understanding regarding specific TBI-related conditions including post-concussive syndrome (PCS) and chronic traumatic encephalopathy (CTE). Data were collected from 307 domestic and 73 international individuals via online researcher-developed survey instrumentation utilizing the Amazon Mechanical Turk marketplace, a recently developed website that allows for a streamlined process of survey-based participant recruitment and data collection. Participants completed background demographics questions, a 31-item true/false questionnaire pertaining to TBI-related knowledge, and an inquiry related to willingness to allow (future) child(ren) to participate in several popular U.S. sports. The overall accuracy rate of our U.S. sample was 61%. No accuracy differences were present for gender or geographic region (p's > .05). Participants who self-reported a prior concussion diagnosis, who reported receiving formal concussion training, and who endorsed participation in collegiate, semi-professional, or professional athletic competition, all exhibited lower accuracy rates than the respective comparison groups (p's < .001). Finally, individual item analysis revealed the presence of significant misconceptions pertaining to PCS and CTE. Misconceptions regarding TBI remain highly prevalent within the general public and may be explained, to some extent, by inefficiencies in current TBI-education practices. Moreover, misconceptions regarding PCS and CTE are also prevalent and likely reflect inconsistencies in the scientific literature, coupled with misleading media reports. To combat these trends, greater emphasis must be placed on construct definition within the field and streamlined, efficient communication with the general public.

  5. Current Knowledge and Future Research on Infant Feeding in the Context of HIV: Basic, Clinical, Behavioral, and Programmatic Perspectives12

    Science.gov (United States)

    Young, Sera L.; Mbuya, Mduduzi N. N.; Chantry, Caroline J.; Geubbels, Eveline P.; Israel-Ballard, Kiersten; Cohan, Deborah; Vosti, Stephen A.; Latham, Michael C.

    2011-01-01

    In 2008, between 129,000 and 194,000 of the 430,000 pediatric HIV infections worldwide were attributable to breastfeeding. Yet in many settings, the health, economic, and social consequences of not breastfeeding would have dire consequences for many more children. In the first part of this review we provide an overview of current knowledge about infant feeding in the context of HIV. Namely, we describe the benefits and risks of breastmilk, the evolution of recommended infant feeding modalities in high-income and low-income countries in the last two decades, and contextualize the recently revised guidelines for infant feeding in the context of HIV current knowledge. In the second section, we suggest areas for future research on the postnatal prevention of mother-to-child transmission of HIV (PMTCT) in developing and industrialized countries. We suggest two shifts in perspective. The first is to evaluate PMTCT interventions more holistically, to include the psychosocial and economic consequences as well as the biomedical ones. The second shift in perspective should be one that contextualizes postnatal PMTCT efforts in the cascade of maternal health services. We conclude by discussing basic, clinical, behavioral, and programmatic research questions pertaining to a number of PMTCT efforts, including extended postnatal ARV prophylaxis, exclusive breastfeeding promotion, counseling, breast milk pasteurization, breast milk banking, novel techniques for making breast milk safer, and optimal breastfeeding practices. We believe the research efforts outlined here will maximize the number of healthy, thriving, HIV-free children around the world. PMID:22332055

  6. Ecology of zoonotic infectious diseases in bats: current knowledge and future directions.

    Science.gov (United States)

    Hayman, D T S; Bowen, R A; Cryan, P M; McCracken, G F; O'Shea, T J; Peel, A J; Gilbert, A; Webb, C T; Wood, J L N

    2013-02-01

    Bats are hosts to a range of zoonotic and potentially zoonotic pathogens. Human activities that increase exposure to bats will likely increase the opportunity for infections to spill over in the future. Ecological drivers of pathogen spillover and emergence in novel hosts, including humans, involve a complex mixture of processes, and understanding these complexities may aid in predicting spillover. In particular, only once the pathogen and host ecologies are known can the impacts of anthropogenic changes be fully appreciated. Cross-disciplinary approaches are required to understand how host and pathogen ecology interact. Bats differ from other sylvatic disease reservoirs because of their unique and diverse lifestyles, including their ability to fly, often highly gregarious social structures, long lifespans and low fecundity rates. We highlight how these traits may affect infection dynamics and how both host and pathogen traits may interact to affect infection dynamics. We identify key questions relating to the ecology of infectious diseases in bats and propose that a combination of field and laboratory studies are needed to create data-driven mechanistic models to elucidate those aspects of bat ecology that are most critical to the dynamics of emerging bat viruses. If commonalities can be found, then predicting the dynamics of newly emerging diseases may be possible. This modelling approach will be particularly important in scenarios when population surveillance data are unavailable and when it is unclear which aspects of host ecology are driving infection dynamics. © 2012 Blackwell Verlag GmbH.

  7. Ecology of zoonotic infectious diseases in bats: current knowledge and future directions

    Science.gov (United States)

    Hayman, D.T.; Bowen, R.A.; Cryan, P.M.; McCracken, G.F.; O'Shea, T.J.; Peel, A.J.; Gilbert, A.; Webb, C.T.; Wood, J.L.

    2013-01-01

    Bats are hosts to a range of zoonotic and potentially zoonotic pathogens. Human activities that increase exposure to bats will likely increase the opportunity for infections to spill over in the future. Ecological drivers of pathogen spillover and emergence in novel hosts, including humans, involve a complex mixture of processes, and understanding these complexities may aid in predicting spillover. In particular, only once the pathogen and host ecologies are known can the impacts of anthropogenic changes be fully appreciated. Cross-disciplinary approaches are required to understand how host and pathogen ecology interact. Bats differ from other sylvatic disease reservoirs because of their unique and diverse lifestyles, including their ability to fly, often highly gregarious social structures, long lifespans and low fecundity rates. We highlight how these traits may affect infection dynamics and how both host and pathogen traits may interact to affect infection dynamics. We identify key questions relating to the ecology of infectious diseases in bats and propose that a combination of field and laboratory studies are needed to create data-driven mechanistic models to elucidate those aspects of bat ecology that are most critical to the dynamics of emerging bat viruses. If commonalities can be found, then predicting the dynamics of newly emerging diseases may be possible. This modelling approach will be particularly important in scenarios when population surveillance data are unavailable and when it is unclear which aspects of host ecology are driving infection dynamics.

  8. Poly(aspartic acid) (PAA) hydrolases and PAA biodegradation: current knowledge and impact on applications.

    Science.gov (United States)

    Hiraishi, Tomohiro

    2016-02-01

    Thermally synthesized poly(aspartic acid) (tPAA) is a bio-based, biocompatible, biodegradable, and water-soluble polymer that has a high proportion of β-Asp units and equivalent moles of D- and L-Asp units. Poly(aspartic acid) (PAA) hydrolase-1 and hydrolase-2 are tPAA biodegradation enzymes purified from Gram-negative bacteria. PAA hydrolase-1 selectively cleaves amide bonds between β-Asp units via an endo-type process, whereas PAA hydrolase-2 catalyzes the exo-type hydrolysis of the products of tPAA hydrolysis by PAA hydrolase-1. The novel reactivity of PAA hydrolase-1 makes it a good candidate for a biocatalyst in β-peptide synthesis. This mini-review gives an overview of PAA hydrolases with emphasis on their biochemical and functional properties, in particular, PAA hydrolase-1. Functionally related enzymes, such as poly(R-3-hydroxybutyrate) depolymerases and β-aminopeptidases, are compared to PAA hydrolases. This mini-review also provides findings that offer an insight into the catalytic mechanisms of PAA hydrolase-1 from Pedobacter sp. KP-2.

  9. Cell-based therapy in Alzheimer’s disease:Current knowledge and perspective

    Institute of Scientific and Technical Information of China (English)

    Liyan Qiao; Hongyun Huang; Lin Chen

    2016-01-01

    Alzheimer’s disease (AD) is the most prevalent type of dementia, and its neuropathology is characterized by the deposition of insolubleβ‐amyloid (Aβ) peptides, intracellular neurofibrillary tangles, amyloid angiopathy, age‐related brain atrophy, synaptic pathology, white matter rarefaction, granulovacuolar degeneration, neuron loss, and neuroinflammation. Although much is known about the neurobiology of AD, very few conventional therapies are available to arrest or slow the disease. There is an urgent need for novel therapeutic approaches for AD. AD subjects have significantly fewer viable precursor cells in the hippocampus compared with age‐matched healthy control subjects. However, the viable precursor cells that remain in AD and age‐matched healthy control brain specimens can be induced to differentiate. To facilitate or mimic the natural compensatory effect in AD, cell therapy, including endogenous and exogenous stem cells, has been considered in AD. In this review, we focus on the history and development of cell therapy in AD, and consider the role of cell therapy as a potential treatment for AD.

  10. Surgical templates for dental implant positioning; current knowledge and clinical perspectives

    Directory of Open Access Journals (Sweden)

    Mohammed Zaheer Kola

    2015-01-01

    Full Text Available Dental implants have been used in a variety of different forms for many years. Since the mid-20 th century, there has been an increase in interest in the implant process for the replacement of missing teeth. Branemark was one of the initial pioneers who applied scientifically based research techniques to develop an endosseous implant that forms an immobile connection with bone. The need for a dental implant to completely address multiple physical and biological factors imposes tremendous constraints on the surgical and handling protocol. Metallic dental implants have been successfully used for decades, but they have serious shortcomings related to their bony union and the fact that their mechanical properties do not match those of bone. However, anatomic limitation and restorative demands encourage the surgeon to gain precision in planning and surgical positioning of dental implants. Ideal placement of the implant facilitates the establishment of favorable forces on the implants and the prosthetic component as well as ensures an aesthetic outcome. Therefore, it is advisable to establish a logical continuity between the planned restoration and the surgical phases, it is essential to use a transfer device that for sure increases the predictability of success. The surgical guide template is fabricated by a dental technician after the presurgical restorative appointments that primarily include determination of occlusal scheme and implant angulations. Here, authors genuinely attempted to review the evolution and clinical applicability of surgical templates used in the placement of dental implants.

  11. Review of the effects of protection in marine protected areas: current knowledge and gaps

    Directory of Open Access Journals (Sweden)

    Ojeda–Martínez, C.

    2011-06-01

    Full Text Available The effectiveness of marine protected areas (MPAs and the conservation of marine environments must be based on reliable information on the quality of the marine environment that can be obtained in a reasonable timeframe. We reviewed studies that evaluated all aspects related to the effectiveness of MPAs in order to describe how the studies were conducted and to detect fields in which research is lacking. Existing parameters used to evaluate the effectiveness of MPAs are summarised. Two-hundred and twenty-two publications were reviewed. We identified the most commonly used study subjects and methodological approaches. Most of the studies concentrated on biological parameters. Peer reviewed studies were based on control vs. impact design. BACI and mBACI designs were used in very few studies. Through this review, we have identified gaps in the objectives assigned to MPAs and the way in which they have been evaluated. We suggest some guidelines aimedat improving the assessment of the effects of protection in MPAs.

  12. IgG4-related disease: current challenges and future prospects

    Directory of Open Access Journals (Sweden)

    Lang D

    2016-02-01

    Full Text Available David Lang,1 Jochen Zwerina,2 Herwig Pieringer1,3 1Second Department of Internal Medicine, Kepler University Clinic, Linz, 2First Department of Internal Medicine, Ludwig Boltzmann-Institute of Osteology, Hanusch Hospital, Vienna, 3Paracelsus Private Medical University, Salzburg, Austria Abstract: Immunoglobulin G4-related disease (IgG4-RD represents an immune-mediated fibroinflammatory condition with a characteristic histopathological appearance that can affect various organs. Although numerous single-organ manifestations have been described more than a century ago, its systemic nature and unique features were only discovered in the last 2 decades, when IgG4-RD emerged as a new entity of disease. IgG4-RD is usually considered a rare disease, but its true epidemiology has not yet been fully clarified. Also, despite recent advances in the identification of the underlying immunological processes, its pathophysiology is only incompletely understood till now. The diagnostic workup of IgG4-RD is complex and usually requires a combination of clinical examination, imaging, histological, and serological analyses. However, no finding alone is specific for IgG4-RD. Therefore, its diagnosis requires careful interpretation of examination results in context with the patient’s clinical appearance as well as the exclusion of a broad variety of differential diagnoses. The past years brought rapid advances concerning this novel disease entity: diagnostic criteria, further insights into the underlying immunological processes, new biomarkers, and novel therapeutic approaches were proposed and widened the knowledge in the field of IgG4-RD. Still, a greater number of questions remain unanswered, and many recent developments require further discussion and proof from clinical trials. This review should give an overview on current knowledge and future perspectives in epidemiology, pathophysiology, diagnosis, and therapy of IgG4-RD. Keywords: PET/CT, autoimmune

  13. Black (pyrogenic) carbon: a synthesis of current knowledge and uncertainties with special consideration of boreal regions

    Science.gov (United States)

    Preston, C. M.; Schmidt, M. W. I.

    2006-09-01

    The carbon (C) cycle in boreal regions is strongly influenced by fire, which converts biomass and detrital C mainly to gaseous forms (CO2 and smaller proportions of CO and CH4), and some 1-3% of mass to pyrogenic C (PyC). PyC is mainly produced as solid charred residues, including visually-defined charcoal, and a black carbon (BC) fraction chemically defined by its resistance to laboratory oxidation, plus much lower proportions of volatile soot and polycyclic aromatic hydrocarbons (PAHs). All PyC is characterized by fused aromatic rings, but varying in cluster sizes, and presence of other elements (N, O) and functional groups. The range of PyC structures is often described as a continuum from partially charred plant materials, to charcoal, soot and ultimately graphite which is formed by the combination of heat and pressure. There are several reasons for current interest in defining more precisely the role of PyC in the C cycle of boreal regions. First, PyC is largely resistant to decomposition, and therefore contributes to very stable C pools in soils and sediments. Second, it influences soil processes, mainly through its sorption properties and cation exchange capacity, and third, soot aerosols absorb solar radiation and may contribute to global warming. However, there are large gaps in the basic information needed to address these topics. While charcoal is commonly defined by visual criteria, analytical methods for BC are mainly based on various measures of oxidation resistance, or on yield of benzenepolycarboxylic acids. These methods are still being developed, and capture different fractions of the PyC structural continuum. There are few quantitative reports of PyC production and stocks in boreal forests (essentially none for boreal peatlands), and results are difficult to compare due to varying experimental goals and methods, as well as inconsistent terminology. There are almost no direct field measurements of BC aerosol production from boreal wildfires, and

  14. Black (pyrogenic carbon: a synthesis of current knowledge and uncertainties with special consideration of boreal regions

    Directory of Open Access Journals (Sweden)

    C. M. Preston

    2006-01-01

    Full Text Available The carbon (C cycle in boreal regions is strongly influenced by fire, which converts biomass and detrital C mainly to gaseous forms (CO2 and smaller proportions of CO and CH4, and some 1–3% of mass to pyrogenic C (PyC. PyC is mainly produced as solid charred residues, including visually-defined charcoal, and a black carbon (BC fraction chemically defined by its resistance to laboratory oxidation, plus much lower proportions of volatile soot and polycyclic aromatic hydrocarbons (PAHs. All PyC is characterized by fused aromatic rings, but varying in cluster sizes, and presence of other elements (N, O and functional groups. The range of PyC structures is often described as a continuum from partially charred plant materials, to charcoal, soot and ultimately graphite which is formed by the combination of heat and pressure. There are several reasons for current interest in defining more precisely the role of PyC in the C cycle of boreal regions. First, PyC is largely resistant to decomposition, and therefore contributes to very stable C pools in soils and sediments. Second, it influences soil processes, mainly through its sorption properties and cation exchange capacity, and third, soot aerosols absorb solar radiation and may contribute to global warming. However, there are large gaps in the basic information needed to address these topics. While charcoal is commonly defined by visual criteria, analytical methods for BC are mainly based on various measures of oxidation resistance, or on yield of benzenepolycarboxylic acids. These methods are still being developed, and capture different fractions of the PyC structural continuum. There are few quantitative reports of PyC production and stocks in boreal forests (essentially none for boreal peatlands, and results are difficult to compare due to varying experimental goals and methods, as well as inconsistent terminology. There are almost no direct field measurements of BC aerosol production from boreal

  15. Black (pyrogenic carbon in boreal forests: a synthesis of current knowledge and uncertainties

    Directory of Open Access Journals (Sweden)

    C. M. Preston

    2006-02-01

    Full Text Available The carbon (C cycle in boreal regions is strongly influenced by fire, which converts biomass and detrital C mainly to gaseous forms (CO2 and smaller proportions of CO and CH4, and some 1–7% of mass to pyrogenic C (PyC. PyC is mainly produced as solid charred residues, including visually-defined charcoal, and a black carbon (BC fraction chemically defined by its resistance to laboratory oxidation, plus much lower proportions of volatile soot and polycyclic aromatic hydrocarbons (PAHs. All PyC is characterized by fused aromatic rings, but varying in cluster sizes, and presence of other elements (N, O and functional groups. There are several reasons for current interest in defining more precisely the role of PyC in the C cycle of boreal regions. First, PyC is resistant to decomposition, and therefore contributes to very stable C pools in soils and sediments. Second, it influences soil processes, mainly through its sorption properties and cation exchange capacity, and third, soot aerosols absorb solar radiation and may contribute to global warming. However, there are large gaps in the basic information needed to address these topics. While charcoal is commonly defined by visual criteria, analytical methods for BC are mainly based on various measures of oxidation resistance, or on yield of benzenepolycarboxylic acids. These methods are still being developed, and capture different fractions of the PyC "continuum". There are few quantitative reports of PyC production and stocks in boreal forests (essentially none for boreal peatlands, and results are difficult to compare due to varying experimental goals and methods, as well as inconsistent terminology. There are almost no direct field measurements of BC aerosol production from boreal wildfires, and little direct information on rates and mechanisms for PyC loss. Structural characterization of charred biomass and forest floor from wildfires generally indicates a low level of

  16. A Social-Learning Approach to Hazard-Related Knowledge Exchange: Boundary Workers at the Geoscience-Humanitarian Interface

    Science.gov (United States)

    Quinn, Keira; Hope, Max; McCloskey, John

    2014-05-01

    A Social-Learning Approach to Hazard-Related Knowledge Exchange: Boundary Workers at the Geoscience-Humanitarian Interface Keira Quinn (1), Dr Max Hope (1), Professor John McCloskey (1). (1)University of Ulster Peer-reviewed science has the potential to guide policy-makers and practitioners in developing robust responses to social problems and issues. Despite advances in hazard-related science, it can often be a challenge to translate findings into useful social applications. With natural hazards affecting 2.9 billion people between 2000 and 2012 the need for hazard science to be effectively communicated is undeniable. This is particularly so in humanitarian contexts as non-governmental organisations (NGOs) play a key role in the poorer nations most affected by natural disasters. Past methods of 'knowledge transfer' have tended to lead to misinterpretations and misrepresentations of science to the extent that it is often used incorrectly or not at all. 'Knowledge exchange' is currently heralded as a more effective means of bringing about successful communication and understanding, and is characterised by the presence of shared learning. Central to a knowledge exchange approach is an understanding of the social and organisational contexts within which learning takes place. Here we use Etienne Wenger's social-learning approach to analyse selected aspects of the social context influencing knowledge exchange across the geoscience-humanitarian interface. For Wenger (2000) Communities of Practice (CoP) are bounded organisational and social groups united by their own distinct values, goals and ways of working. The boundaries surrounding CoPs can act as barriers to knowledge exchange but can also create opportunities for new shared learning by challenging existing perspectives and practice. Drawing on the findings of ongoing qualitative research into communication and learning between earthquake scientists and humanitarian NGOs in UK/Ireland, this paper outlines a number

  17. Inflammatory reactions in onchocerciasis: a report on current knowledge and recommendations for further study*

    Science.gov (United States)

    Henson, P. M.; Mackenzie, C. D.; Spector, W. G.

    1979-01-01

    This report concerns the host's reactions to the presence of the parasite both in the course of the natural disease and during drug treatment. The various stages of Onchocerca volvulus are discussed in terms of the type of tissue reaction seen. The discussion then turns to basic hypotheses concerning the etiology of these reactions, emphasis being placed on the fact that while pathological changes are considerable in some locations there is a remarkable lack of reaction in others. Some of the mechanisms possibly involved in this apparent absence of host response are discussed, including anti-complement factors, poor antigenicity, acquisition of host antigen, immune tolerance, and blocking antibodies. In any study of the inflammatory response it is recommended that critical evaluations be made of histological material, haematological studies, the definition of the antigenic nature of O. volvulus, characterization of immunological reactivity of patients, and the definition of the migratory pathways of the parasite. The marked host reactions seen following chemotherapy, especially those related to the interaction of the drug diethylcarbamazine with microfilariae, are discussed at some length. The etiology of these reactions is considered and recommendations are made for the experimental elucidation of the mechanisms involved. Emphasis is placed on the necessity for detailed sequential histopathological and immunopathological studies in the definition of the tissue lesions found in onchocerciasis. Characterization of these lesions will assist greatly the approach to control of the adverse reactions seen during treatment. The use of anti-inflammatory agents in clinical trials is discussed and comments are made concerning the most suitable clinical situations for testing drugs and the types of drug that should be tested. PMID:396050

  18. Inflammatory reactions in onchocerciasis: a report on current knowledge and recommendations for further study.

    Science.gov (United States)

    Henson, P M; Mackenzie, C D; Spector, W G

    1979-01-01

    This report concerns the host's reactions to the presence of the parasite both in the course of the natural disease and during drug treatment. The various stages of Onchocerca volvulus are discussed in terms of the type of tissue reaction seen. The discussion then turns to basic hypotheses concerning the etiology of these reactions, emphasis being placed on the fact that while pathological changes are considerable in some locations there is a remarkable lack of reaction in others. Some of the mechanisms possibly involved in this apparent absence of host response are discussed, including anti-complement factors, poor antigenicity, acquisition of host antigen, immune tolerance, and blocking antibodies. In any study of the inflammatory response it is recommended that critical evaluations be made of histological material, haematological studies, the definition of the antigenic nature of O. volvulus, characterization of immunological reactivity of patients, and the definition of the migratory pathways of the parasite.The marked host reactions seen following chemotherapy, especially those related to the interaction of the drug diethylcarbamazine with microfilariae, are discussed at some length. The etiology of these reactions is considered and recommendations are made for the experimental elucidation of the mechanisms involved. Emphasis is placed on the necessity for detailed sequential histopathological and immunopathological studies in the definition of the tissue lesions found in onchocerciasis. Characterization of these lesions will assist greatly the approach to control of the adverse reactions seen during treatment.The use of anti-inflammatory agents in clinical trials is discussed and comments are made concerning the most suitable clinical situations for testing drugs and the types of drug that should be tested.

  19. Novel strategies to mine alcoholism-related haplotypes and genes by combining existing knowledge framework.

    Science.gov (United States)

    Zhang, RuiJie; Li, Xia; Jiang, YongShuai; Liu, GuiYou; Li, ChuanXing; Zhang, Fan; Xiao, Yun; Gong, BinSheng

    2009-02-01

    High-throughout single nucleotide polymorphism detection technology and the existing knowledge provide strong support for mining the disease-related haplotypes and genes. In this study, first, we apply four kinds of haplotype identification methods (Confidence Intervals, Four Gamete Tests, Solid Spine of LD and fusing method of haplotype block) into high-throughout SNP genotype data to identify blocks, then use cluster analysis to verify the effectiveness of the four methods, and select the alcoholism-related SNP haplotypes through risk analysis. Second, we establish a mapping from haplotypes to alcoholism-related genes. Third, we inquire NCBI SNP and gene databases to locate the blocks and identify the candidate genes. In the end, we make gene function annotation by KEGG, Biocarta, and GO database. We find 159 haplotype blocks, which relate to the alcoholism most possibly on chromosome 1 approximately 22, including 227 haplotypes, of which 102 SNP haplotypes may increase the risk of alcoholism. We get 121 alcoholism-related genes and verify their reliability by the functional annotation of biology. In a word, we not only can handle the SNP data easily, but also can locate the disease-related genes precisely by combining our novel strategies of mining alcoholism-related haplotypes and genes with existing knowledge framework.

  20. Novel strategies to mine alcoholism-related haplotypes and genes by combining existing knowledge framework

    Institute of Scientific and Technical Information of China (English)

    ZHANG RuiJie; LI Xia; JIANG YongShuai; LIU GuiYou; LI ChuanXing; ZHANG Fan; XIAO Yun; GONG BinSheng

    2009-01-01

    High-throughout single nucleotide polymorphism detection technology and the existing knowledge provide strong support for mining the disease-related haplotypes and genes. In this study, first, we apply four kinds of haplotype identification methods (Confidence Intervals, Four Gamete Testa, Solid Spine of LD and fusing method of haplotype block) into high-throughout SNP genotype data to identify blocks, then use cluster analysis to verify the effectiveness of the four methods, and select the alcoholism-related SNP haplotypes through risk analysis. Second, we establish a mapping from haplotypes to alcoholism-related genes. Third, we inquire NCBI SNP and gene databases to locate the blocks and identify the candidate genes. In the end, we make gene function annotation by KEGG, Biocarta, and GO database. We find 159 haplotype blocks, which relate to the alcoholism most possibly on chromosome 1-22, including 227 haplotypes, of which 102 SNP haplotypes may increase the risk of alcoholism. We get 121 alcoholism-related genes and verify their reliability by the functional annotation of biology. In a word, we not only can handle the SNP data easily, but also can locate the disease-related genes precisely by combining our novel strategies of mining alcoholism-related haplotypes and genes with existing knowledge framework.

  1. Novel strategies to mine alcoholism-related haplotypes and genes by combining existing knowledge framework

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    High-throughout single nucleotide polymorphism detection technology and the existing knowledge provide strong support for mining the disease-related haplotypes and genes. In this study, first, we apply four kinds of haplotype identification methods (Confidence Intervals, Four Gamete Tests, Solid Spine of LD and fusing method of haplotype block) into high-throughout SNP genotype data to identify blocks, then use cluster analysis to verify the effectiveness of the four methods, and select the alco- holism-related SNP haplotypes through risk analysis. Second, we establish a mapping from haplotypes to alcoholism-related genes. Third, we inquire NCBI SNP and gene databases to locate the blocks and identify the candidate genes. In the end, we make gene function annotation by KEGG, Biocarta, and GO database. We find 159 haplotype blocks, which relate to the alcoholism most possibly on chromosome 1~22, including 227 haplotypes, of which 102 SNP haplotypes may increase the risk of alcoholism. We get 121 alcoholism-related genes and verify their reliability by the functional annotation of biology. In a word, we not only can handle the SNP data easily, but also can locate the disease-related genes pre- cisely by combining our novel strategies of mining alcoholism-related haplotypes and genes with ex- isting knowledge framework.

  2. Current Knowledge of Mesozoic Coleoptera from Daohugou and Liaoning (Northeast China)

    Institute of Scientific and Technical Information of China (English)

    Alexander G.KIREJTSHUK; Alexander G.PONOMARENKO; Alexander A.PROKIN; CHANG Huali; Georgy V.NIKOLAJEV; REN Dang

    2010-01-01

    The present paper is devoted to an overview on fossil Coleoptera studied from Inner Mongolia,Daohugou (Middle Jurassic,Jiulongshan Formation) and Liaoning (Upper Jurassic-Lower Cretaceous,Yixian Formation) deposited in Chinese collections.As a result,species of the tribe Sperchopsini and Hydrophilini from Hydrophilidae,families and subfamilies Silphidae,Syndesinae from Lucanidae,Pleocomidae,Trogidae,Trogissitidae,Pyrochroidae,Diaperinae from Tenebrionidae,and Cerambycidae were first registered in the Mesozoic and some families were defined as new.It was shown that many superfamilies represented in the Recent Fauna were formed within the Middle Jurassic and Lower Cretaceous.The materials examined confirm the hypothesis that Cucujiformian beetles are a younger group than other infraordera of Polyphaga (Staphyliniformia and Elateriformia) and,therefore,they appeared in the fossil record only in the late Mesozoic.It was shown and confirmed that most superfamilies appeared in the fossil records before Cucujoidea.The synonymy of Notocupes Ponomarenko,1964;Sinocupes Lin,1976,syn.nov.;Amblomma Tan,Ren et Liu 2005,syn.nov.;Euryomma Tan,Ren et Shih,2006,syn.nov.,non Stein,1899 and Ovatocupes Tan et Ren,2006,syn.nov.;synonymy of Tetraphalerus Waterhouse,1901 and Odontomma Tan,Ren et Ge 2006,syn.nov.;and synonymy of Priacmopsis Ponomarenko,1966 and Latocupes Tan et Ren,2006,syn.nov.are proposed.Sinorhombocoleus papposus Tan et Ren,2009 is transferred from the family Rhombocoleidae to Schizophoridae.Cervicatinius complanus Tan,Ren et Shih,2007 and Forticatinius elegans Tan,Ren et Shih,2007 are transferred from the family Catiniidae (suborder Archostemata) to superfamily Cleroidea (suborder Polyphaga:first among the family Peltidae and second as a closely related group to the latter family).The family Parandrexidae is transferred from the superfamily Cucujoidea to Cieroidea.The ecological circumstances of the past ecosystems and hypotheses of historical development of the order

  3. Current and future threats and opportunities facing European crop wild relatives and landrace diversity

    NARCIS (Netherlands)

    Maxted, N.; Akparov, Z.I.; Aronsson, M.; Kik, C.

    2012-01-01

    The approach of this priority crop wild relatives (CWR) and landraces (LR) conservation exercise was to use the skills and knowledge of 52 ECPGR in situ and on-farm conservation network members and other conference delegates, representing a broad European range of PGR-related academic, research and

  4. The Link between Knowledge, Attitudes and Practices in Relation to Atmospheric Haze Pollution in Peninsular Malaysia

    OpenAIRE

    Laura De Pretto; Stephen Acreman; Matthew J Ashfold; Mohankumar, Suresh K.; Ahimsa Campos-Arceiz

    2015-01-01

    Transboundary haze episodes caused by seasonal forest fires have become a recurrent phenomenon in Southeast Asia, with serious environmental, economic, and public health implications. Here we present a cross-sectional survey conducted among people in Kuala Lumpur and surrounds to assess the links between knowledge, attitudes, and practices in relation to the transboundary haze episodes. Of 305 respondents, 125 were amateur athletes participating in a duathlon event and the remainder were surv...

  5. Health-related knowledge of primary prevention of cancer in Portugal.

    Science.gov (United States)

    Costa, Ana Rute; Silva, Susana; Moura-Ferreira, Pedro; Villaverde-Cabral, Manuel; Santos, Osvaldo; do Carmo, Isabel; Barros, Henrique; Lunet, Nuno

    2016-01-01

    The increasing number of new cases of cancer highlights the relevance of primary prevention for cancer control, which is influenced, among other factors, by the population's health-related knowledge. Therefore, we aimed to describe cancer-related knowledge in Portugal, including perception of risk, awareness of cancer causes and preventive behaviours. We evaluated 1624 Portuguese-speaking dwellers, aged between 16 and 79 years, through face-to-face interviews conducted using a structured questionnaire. We computed adjusted (sex, age, education) regression coefficients and prevalence ratios, using linear and Poisson regression, respectively, to quantify associations with cancer-specific knowledge. The proportions of nonresponse ranged from 13.4 to 63.5% for the most frequent cancer in Portugal and the leading cause of cancer, respectively. The mean of the estimated lifetime risk of cancer in the Portuguese population was 37.0%. A total of 47.5% of the respondents identified breast cancer as the most frequent in Portugal, 72.0% named lifestyles as the leading cause of cancer and 40.2% selected not smoking as the most important preventive behaviour. Lower levels of education were associated with higher proportions of nonresponse, but not consistently with inaccurate knowledge. Men provided lower estimates of the lifetime risk of cancer, indicated breast cancer less frequently and more often lung cancer as the most frequent, and were more likely to select not smoking as the most important preventive behaviour. The present study provides relevant data on knowledge of cancer prevention, which may be used for the planning and evaluation of awareness-raising and primary prevention interventions in Portugal.

  6. Portuguese Coaches' Perceptions of and Preferences for Knowledge Sources Related to their Professional Background.

    Science.gov (United States)

    Mesquita, Isabel; Isidro, Sofia; Rosado, António

    2010-01-01

    The purpose of this study was to analyse Portuguese coaches' perceptions of, and preferences for, knowledge sources as related to professional background; namely academic education level, coach education level and coaching experience. The study's participants comprised 336 Portuguese coaches from twenty-two sports. A questionnaire was used to identify coaches' demographic characteristics and representations about their preferred sources of coaching knowledge. MANOVA using Tukey's HSD test was used to compare groups. The results highlighted that coaches perceived that coaching knowledge is built from a broad range of sources from personal coaching and playing experiences to more explicit formal, informal and non-formal learning situations. Results indicated that the coaches ascribed more importance to experiential sources such as working with experts, learning by doing, interacting with peer coaches and attending informal seminars and clinics, than to the formal learning situations provided by the national coaching certification programs. Differences, however, were found in that coaches who had a greater background within higher education (physical) and sport valued informal and non-formal learning sources more than did coaches who were defined as not coming from an academic background. The findings point to the importance of developing new learning, experientially-based, opportunities within the Portuguese context, where curricula content continues to be delivered via didactic means. Key pointsCoaches recognized that learning is obtained from a broad range of sources of coaching knowledge and each source has a particular role in the development of a coach.Experiential guided sources reached more importance to coaches as working with experts, learning by doing, attending seminars/clinics outside of the formal system and interaction with peers were the most acknowledged.The only source that is related to formal learning, national certification programs, was

  7. Transformational leadership and safety performance among nurses: the mediating role of knowledge-related job characteristics.

    Science.gov (United States)

    Lievens, Ilse; Vlerick, Peter

    2014-03-01

    To report the impact of transformational leadership on two dimensions of nurses' safety performance (i.e. safety compliance and safety participation) and to study the mediating role of knowledge-related job characteristics in this relationship. Safety performance refers to the behaviours that employees exhibit to adhere to safety guidelines and to promote health and safety at their workplace. Nurses' safety performance is a major challenge for healthcare settings, urging the need to identify the key determinants and psychological mechanisms that influence it. A cross-sectional survey study. The study was carried out in September 2010 in a large Belgian hospital. We used self-administered questionnaires; 152 nurses participated. The hypotheses were tested using hierarchical regression analyses. In line with our first hypothesis, the results show that transformational leadership exerted a significant positive impact on both dimensions of nurses' safety performance. This positive relation was mediated by knowledge-related job characteristics, supporting our second hypothesis. Head nurses' transformational leadership can enhance nurses' compliance with and participation in safety. Furthermore, transformational head nurses are able to influence the perception that their nurses have about the kind and amount of knowledge in their job, which can also lead to increases in both dimensions of nurses' safety performance. This study therefore demonstrates the key impact that transformational head nurses have, both directly and indirectly, on the safety performance of their nurses. © 2013 John Wiley & Sons Ltd.

  8. Belief, Knowledge and Understanding. How to Deal with the Relations Between Different Cultural Perspectives in Classrooms

    Science.gov (United States)

    Moreira-dos-Santos, Frederik; El-Hani, Charbel N.

    2017-05-01

    This article discusses how to deal with the relations between different cultural perspectives in classrooms, based on a proposal for considering understanding and knowledge as goals of science education, inspired by Dewey's naturalistic humanism. It thus combines educational and philosophical interests. In educational terms, our concerns relate to how science teachers position themselves in multicultural classrooms. In philosophical terms, we are interested in discussing the relations between belief, understanding, and knowledge under the light of Dewey's philosophy. We present a synthesis of Dewey's theory of inquiry through his naturalistic humanism and discuss its implications for the concepts of belief, understanding, and knowledge, as well as for the goals of science teaching. In particular, we highlight problems arising in the context of possible conflicts between scientific and religious claims in the school environment that result from totalitarian positions. We characterize an individual's position as totalitarian if he or she takes some way of thinking as the only one capable of expressing the truth about all that exists in the world, lacks open-mindedness to understand different interpretative perspectives, and attempts to impose her or his interpretation about the facts to others by violent means or not. From this stance, any other perspective is taken to be false a priori and, accordingly, as a putative target to be suppressed or adapted to the privileged way of thinking. We argue, instead, for a more fallibilist evaluation of our own beliefs and a more respectful appraisal of the diversity of students' beliefs by both students and teachers.

  9. Health-Related Fitness Knowledge and Its Relation to Student Physical Activity Patterns at a Large U.S. Southern State University

    Science.gov (United States)

    Keating, Xiaofen D.; Castro-Pinero, Jose; Centeio, Erin; Harrison, Louis, Jr.; Ramirez, Tere; Chen, Li

    2010-01-01

    This study examined student health-related fitness (HRF) knowledge and its relationship to physical activity (PA). The participants were undergraduate students from a large U.S. state university. HRF knowledge was assessed using a test consisting of 150 multiple choice items. Differences in HRF knowledge scores by sex, ethnicity, and years in…

  10. Current Developments in Public Relations and a Review of their Implications on Public Relations Curriculum in Canada.

    Science.gov (United States)

    Wills, Sandra Judith Abiola

    Intended to review the recent professional developments in public relations as they are documented in the literature and to explore the implications of these developments for public relations education in Canada at the university level, this thesis is in six chapters, as follows: (1) Introduction; (2) Defining Public Relations; (3) Current Public…

  11. The relation between Staphylococcus aureus and Wegener's granulomatosis : Current knowledge and future directions

    NARCIS (Netherlands)

    Popa, ER; Tervaert, JWC

    2003-01-01

    To date, in the investigation of the role of S. aureus in WG, we face a paradoxical situation. On the one hand, clinical results obtained from treatment of WG patients with co-trimoxazole and studies assessing the impact of S. aureus on disease relapses strongly suggest that this bacterium contribut

  12. Mining-Related Selenium Contamination in Alaska, and the State of Current Knowledge

    Directory of Open Access Journals (Sweden)

    Aibyek Khamkhash

    2017-03-01

    Full Text Available Selenium pollution has been a topic of extensive research dating back further than the last decade and has attracted significant attention from several environmental and regulatory agencies in order to monitor and control its discharge from myriad industrial sources. The mining industry is a prime contributor of hazardous selenium release in the aquatic systems and is responsible for both acute and chronic impacts on living organisms. Herein we provide an overview of selenium contamination issues, with a specific focus on selenium release from mining industries, including a discussion of various technologies commonly employed to treat selenium-impacted waters from mining discharge. Different cases pertaining to selenium release from Alaskan mines (during years 2000–2015 are also presented, along with measures taken to mitigate high concentration releases. For continued resource exploration and economic development activities, as well as environmental preservation, it is important to fundamentally understand such emerging and pressing issues as selenium contamination and investigate efficient technological approaches to counter these challenges.

  13. An investigation of Saudi Arabian MR radiographers' knowledge and confidence in relation to MR image-quality-related errors.

    Science.gov (United States)

    Alsharif, W; Davis, M; McGee, A; Rainford, L

    2017-05-01

    To investigate MR radiographers' current knowledge base and confidence level in relation to quality-related errors within MR images. Thirty-five MR radiographers within 16 MRI departments in the Kingdom of Saudi Arabia (KSA) independently reviewed a prepared set of 25 MR images, naming the error, specifying the error-correction strategy, scoring how confident they were in recognising this error and suggesting a correction strategy by using a scale of 1-100. The datasets were obtained from MRI departments in the KSA to represent the range of images which depicted excellent, acceptable and poor image quality. The findings demonstrated a low level of radiographer knowledge in identifying the type of quality errors and when suggesting an appropriate strategy to rectify those errors. The findings show that only (n = 7) 20% of the radiographers could correctly name what the quality errors were in 70% of the dataset, and none of the radiographers correctly specified the error-correction strategy in more than 68% of the MR datasets. The confidence level of radiography participants in their ability to state the type of image quality errors was significantly different (p types. The findings of this study suggest there is a need to establish a national association for MR radiographers to monitor training and the development of postgraduate MRI education in Saudi Arabia to improve the current status of the MR radiographers' knowledge and direct high quality service delivery. Copyright © 2016 The College of Radiographers. Published by Elsevier Ltd. All rights reserved.

  14. Toxoplasmosis seroprevalence in relation to knowledge and practice among pregnant women in Dhahran, Saudi Arabia.

    Science.gov (United States)

    Elsafi, Salah H; Al-Mutairi, Wasaef F; Al-Jubran, Khalid M; Abu Hassan, Mohamed M; Al Zahrani, Eidan M

    2015-01-01

    The epidemiological importance of the different routes of Toxoplasma gondii transmission is not known and depends largely on population behaviour and knowledge. This study was conducted to assess toxoplasmosis seropositivity and the related knowledge and preventive practices that are necessary for the prevention of the disease among pregnant women. All pregnant women attending antenatal clinic were tested for T. gondii immunoglobulins followed by a survey questionnaire that tested their knowledge and preventive practice. Statistical comparisons were made between the seropositive and negative ones. We determined a low to moderate seroprevalence of toxoplasmosis among pregnant women in Dhahran, Saudi Arabia as compared to many other parts of the world. The overall positivity rates of IgG and IgM against T. gondii among 400 pregnant women were 28.5 and 3%, respectively. 75.5% of the participants had never heard about toxoplasmosis and the associated risk factors. Lack of knowledge was associated with the higher risk of infection (OR = 4.04, p toxoplasmosis by pregnant women was poor. It is therefore vital to provide a formal education about toxoplasmosis risk factors to women of childbearing age.

  15. The Link between Knowledge, Attitudes and Practices in Relation to Atmospheric Haze Pollution in Peninsular Malaysia.

    Science.gov (United States)

    De Pretto, Laura; Acreman, Stephen; Ashfold, Matthew J; Mohankumar, Suresh K; Campos-Arceiz, Ahimsa

    2015-01-01

    Transboundary haze episodes caused by seasonal forest fires have become a recurrent phenomenon in Southeast Asia, with serious environmental, economic, and public health implications. Here we present a cross-sectional survey conducted among people in Kuala Lumpur and surrounds to assess the links between knowledge, attitudes, and practices in relation to the transboundary haze episodes. Of 305 respondents, 125 were amateur athletes participating in a duathlon event and the remainder were surveyed in an inner-city shopping mall. Across the whole sample, people who possessed more factual information about the haze phenomenon showed significantly higher levels of concern. Duathletes were more knowledgeable than non-duathletes and also more concerned about the negative effects of haze, especially on health. For all people who regularly practice outdoor sports (including people interviewed at the shopping mall), higher levels of knowledge and concerned attitudes translated into a greater likelihood of engaging in protective practices, such as cancelling their outdoor training sessions, while those with greater knowledge were more likely to check the relevant air pollution index on a daily basis. Our results indicate that the provision of accurate and timely information about air quality to residents will translate into beneficial practices, at least among particularly exposed individuals, such as amateur athletes who regularly practice outdoor sports.

  16. HIV-related knowledge, attitudes and practice among health care workers in Montenegro.

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    Gledović, Zorana; Rakočević, Božidarka; Mugoša, Boban; Grgurević, Anita

    2015-03-01

    The objective of the present study was to assess HIV-related knowledge, attitudes, and practice of health care workers (HCWs) in Montenegro. A cross-sectional study was conducted in the University Clinical Centre of Montenegro in Podgorica. A self-administered anonymous questionnaire was used for data collecting. Out of 526 HCWs, 422 were included in the survey and response rate was 80%. An insufficient level of knowledge on HIV transmission and the risk after exposure was observed generally, although the knowledge was better in physicians compared to other HCWs categories. A rather high proportion of HCWs showed inappropriate attitude regarding the need of HIV testing of all hospitalized patients (64.7%) and obligation of HIV+ patient to report his/her HIV status (88.9%) in order to practice universal precaution. Additionally, 6.2% HCWs would refuse to treat an HIV+ patient. More than a half (55.7%) of study participants were educated in HIV/AIDS and 15.9% of them were HIV tested. Majority of HCWs (67.5%) always applied universal precautions during their daily work with patients. In spite of applying protective devices, number of accidents was great. A continuous education is necessary to increase the level of knowledge of HCWs about the risk of infection at the workplace. This would potentially influence the modification of their attitudes regarding HIV patients and improve prevention at the workplace. Continuous research regarding the professional risk would provide better health and safety among medical staff.

  17. The Link between Knowledge, Attitudes and Practices in Relation to Atmospheric Haze Pollution in Peninsular Malaysia.

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    Laura De Pretto

    Full Text Available Transboundary haze episodes caused by seasonal forest fires have become a recurrent phenomenon in Southeast Asia, with serious environmental, economic, and public health implications. Here we present a cross-sectional survey conducted among people in Kuala Lumpur and surrounds to assess the links between knowledge, attitudes, and practices in relation to the transboundary haze episodes. Of 305 respondents, 125 were amateur athletes participating in a duathlon event and the remainder were surveyed in an inner-city shopping mall. Across the whole sample, people who possessed more factual information about the haze phenomenon showed significantly higher levels of concern. Duathletes were more knowledgeable than non-duathletes and also more concerned about the negative effects of haze, especially on health. For all people who regularly practice outdoor sports (including people interviewed at the shopping mall, higher levels of knowledge and concerned attitudes translated into a greater likelihood of engaging in protective practices, such as cancelling their outdoor training sessions, while those with greater knowledge were more likely to check the relevant air pollution index on a daily basis. Our results indicate that the provision of accurate and timely information about air quality to residents will translate into beneficial practices, at least among particularly exposed individuals, such as amateur athletes who regularly practice outdoor sports.

  18. AIDS-related knowledge, stigma and customary beliefs of South African construction workers.

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    Govender, Rajen; Bowen, Paul; Edwards, Peter; Cattell, Keith

    2017-06-01

    Customary beliefs about the cause/s of AIDS are significantly related to whether or not individuals will undergo HIV testing. This study examined the cultural beliefs of construction workers in terms of their demographic and lifestyle behavioural characteristics, and their AIDS-related knowledge and stigma attitudes, to help inform improved work-based AIDS-education interventions by construction firms. A total of 512 workers drawn from 6 firms operating on 18 construction sites in the Western Cape province participated in the study. Thirty-seven per cent of participants either endorsed customary beliefs/explanations about the cause of AIDS, or were unsure. AIDS-related knowledge proved a significant differentiator of participants endorsing customary beliefs (aOR = 0.8, 95% CI, 0.6-1.0), or being unsure (aOR = 0.5, 95% CI, 0.4-0.6), compared to participants not endorsing such beliefs. Stigma (aOR = 1.3, 95% CI, 1.1-1.7) proved a significant differentiator of participants with more polarized beliefs, namely, those endorsing customary beliefs compared to those not endorsing such beliefs, but was not significant in differentiating these categories from that of being unsure. The challenges to testing behaviour from incorrect AIDS knowledge may be amplified by adherence to customary beliefs that discount scientific explanations about the cause of AIDS. Interventions are required to specifically address misinformation or incorrect knowledge about AIDS derived from traditional beliefs, and should explicitly target persons who either endorse such beliefs or are somewhat equivocal about them. The role of peer educators is highlighted. Traditional healers, given their credibility and status within many traditional cultures, may also have an important role to play in this regard.

  19. Determinants of drug abuse in high school students and their related knowledge and attitude.

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    Geramian, Nahid; Akhavan, Shohreh; Gharaat, Leila; Tehrani, Afsaneh Malekpour; Farajzadegan, Ziba

    2012-03-01

    The aim of the current study is to evaluate the knowledge and attitude of high school students toward addicting drugs. Thus, the interventions, which are more appropriate for this age group can be designed and applied. This cross-sectional study was carried out in 2009 in Isfahan province. The study population was high school students, who were randomly selected by multi-stage cluster sampling. The evaluation tool was an author-devised questionnaire, which was filled out by the students. The data obtained was analyzed using SPSS software, version 16. Among 6998 students who filled out the questionnaire, 50.1% were female. The mean knowledge scores were 58.7 +/- 10.3 and 57.9 +/- 10.2 for girls and boys, respectively, which were significantly different (p = 0.002). Considering the scores students obtained in attitude toward inclination to drug abuse, the most important factors in this regard were parents' divorce, familial conflicts, seeking pleasure, adolescents' curiosity, availability of the drugs, peer pressure, low levels of self-confidence, psychological disorders, and strict parents. With respect to the results obtained, promoting the knowledge and modifying the attitude of students, and increasing their self-confidence particularly in schools can play an important role in decreasing drug abuse in this age group. Moreover, policymakers should consider the strategies, which can support the family structure and reduce the harms in unstable families.

  20. Virtualization and New Geographies of Knowledge in Higher Education: Possibilities for the Transformation of Knowledge, Pedagogic Relations and Learner Identities

    Science.gov (United States)

    Taylor, Carol A.; Dunne, Mairead

    2011-01-01

    This article considers some of the ways in which the transformative power of Web 2.0 digital technology is reconfiguring learning, knowledge and academic identities in the contemporary university. Through a focus on five specific examples, we consider the impact of virtualization processes on spatiality, materiality and embodiment, and pedagogic…